# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Hemerythrin PF01814.23 AAAP01000003.1_1 - 0.011 16.3 0.1 0.014 16.1 0.1 1.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain MCPsignal PF00015.21 AAAP01000004.1_1 - 1e-13 51.5 1.1 1.6e-13 50.8 1.1 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TSKS PF15358.6 AAAP01000004.1_1 - 0.0012 17.3 0.7 0.0015 17.0 0.7 1.1 1 0 0 1 1 1 1 Testis-specific serine kinase substrate Baculo_PEP_C PF04513.12 AAAP01000004.1_1 - 0.067 13.2 0.6 2.6 8.1 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 AAAP01000004.1_1 - 0.091 13.2 0.0 0.53 10.8 0.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 AAAP01000004.1_1 - 0.097 12.7 0.4 1.3 9.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01000004.1_1 - 0.13 12.5 0.8 6 7.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Nup88 PF10168.9 AAAP01000004.1_1 - 0.17 9.7 0.0 0.22 9.3 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore component Hist_deacetyl PF00850.19 AAAP01000005.1_1 - 1.3e-52 179.3 2.3 1.6e-52 178.9 2.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Malectin PF11721.8 AAAP01000006.1_1 - 3.1e-05 24.1 0.0 5.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Malectin domain AAA PF00004.29 AAAP01000007.1_1 - 7.5e-48 162.3 0.0 1.1e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AAAP01000007.1_1 - 1.2e-08 34.6 0.0 2.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AAAP01000007.1_1 - 4.6e-08 33.1 0.0 3e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAAP01000007.1_1 - 3.2e-06 26.6 0.0 6.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 AAAP01000007.1_1 - 8e-06 26.3 0.2 0.0007 20.0 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 AAAP01000007.1_1 - 8.8e-05 22.3 0.0 0.00039 20.2 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAAP01000007.1_1 - 0.00021 21.6 0.1 0.028 14.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 AAAP01000007.1_1 - 0.0024 18.0 0.0 0.0062 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 AAAP01000007.1_1 - 0.0042 17.3 0.0 0.0066 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01000007.1_1 - 0.0062 16.0 0.3 0.017 14.5 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AAAP01000007.1_1 - 0.0067 16.0 0.1 0.047 13.2 0.1 2.2 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAAP01000007.1_1 - 0.0068 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 AAAP01000007.1_1 - 0.018 14.7 0.0 0.15 11.8 0.0 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 AAAP01000007.1_1 - 0.028 15.0 0.0 0.046 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAAP01000007.1_1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 AAAP01000007.1_1 - 0.048 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 AAAP01000007.1_1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AAAP01000007.1_1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01000007.1_1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAAP01000007.1_1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 AAAP01000007.1_1 - 0.094 11.9 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 AAAP01000007.1_1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 AAAP01000007.1_1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_PrkA PF08298.11 AAAP01000007.1_1 - 0.12 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Zeta_toxin PF06414.12 AAAP01000007.1_1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 AAAP01000007.1_1 - 0.13 11.9 0.2 0.26 11.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AAAP01000007.1_1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 AAAP01000007.1_1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Phage_TAC_7 PF10109.9 AAAP01000009.1_1 - 3.4e-05 23.9 0.6 8.4 6.6 0.0 5.2 1 1 3 5 5 5 2 Phage tail assembly chaperone proteins, E, or 41 or 14 HTH_26 PF13443.6 AAAP01000009.1_1 - 0.013 15.9 15.5 9.7 6.7 0.3 6.0 1 1 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain Arc_PepC PF06819.11 AAAP01000009.1_1 - 0.093 12.9 0.9 18 5.5 0.0 3.6 1 1 2 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain DUF3275 PF11679.8 AAAP01000009.1_1 - 0.45 10.5 3.3 9.3 6.2 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) PKS_DE PF18369.1 AAAP01000009.1_1 - 2.6 8.7 4.0 14 6.3 0.3 3.4 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain Kringle PF00051.18 AAAP01000012.1_1 - 0.045 14.1 0.0 0.049 14.0 0.0 1.0 1 0 0 1 1 1 0 Kringle domain AAA PF00004.29 AAAP01000014.1_1 - 5.3e-47 159.6 0.0 7.2e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AAAP01000014.1_1 - 8.1e-12 44.7 0.3 1.5e-11 43.9 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 AAAP01000014.1_1 - 7.8e-06 25.7 0.0 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAAP01000014.1_1 - 1e-05 26.0 1.2 7.2e-05 23.2 1.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAAP01000014.1_1 - 1.1e-05 25.5 0.2 0.00011 22.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAAP01000014.1_1 - 5.3e-05 22.6 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 AAAP01000014.1_1 - 8e-05 22.9 0.1 0.016 15.4 0.1 2.3 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAAP01000014.1_1 - 0.0032 17.2 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 AAAP01000014.1_1 - 0.0033 17.2 0.1 0.017 14.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01000014.1_1 - 0.0045 17.2 0.0 0.0065 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01000014.1_1 - 0.0048 16.3 0.1 0.0093 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AAAP01000014.1_1 - 0.0058 16.6 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 AAAP01000014.1_1 - 0.0072 16.5 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 AAAP01000014.1_1 - 0.011 15.4 0.0 0.077 12.7 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 AAAP01000014.1_1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01000014.1_1 - 0.034 14.7 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAAP01000014.1_1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01000014.1_1 - 0.063 12.8 0.4 0.27 10.8 0.1 2.0 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAAP01000014.1_1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 AAAP01000014.1_1 - 0.093 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 AAAP01000014.1_1 - 0.1 12.5 0.0 0.54 10.1 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 AAAP01000014.1_1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 AAAP01000014.1_1 - 0.11 11.9 0.4 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 AAAP01000014.1_1 - 0.14 12.1 0.1 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 AAAP01000014.1_1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AAAP01000014.1_1 - 0.17 11.2 0.0 0.5 9.7 0.1 1.6 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 AAAP01000014.1_1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Radical_SAM PF04055.21 AAAP01000015.1_1 - 1.3e-10 41.9 0.0 1.5e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily fn3 PF00041.21 AAAP01000016.1_1 - 2.3e-13 50.3 1.2 9e-13 48.4 1.2 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Cadherin_5 PF17892.1 AAAP01000016.1_1 - 0.016 15.2 0.9 0.072 13.1 0.1 2.2 2 0 0 2 2 2 0 Cadherin-like domain Big_9 PF17963.1 AAAP01000016.1_1 - 0.036 14.8 0.5 0.036 14.8 0.5 2.9 3 0 0 3 3 3 0 Bacterial Ig domain Tissue_fac PF01108.17 AAAP01000016.1_1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Tissue factor DDE_Tnp_1_6 PF13751.6 AAAP01000019.1_1 - 7e-10 39.2 0.4 7.5e-10 39.1 0.4 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01000019.1_1 - 3.3e-09 36.7 0.1 3.6e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain TetR_C_16 PF17920.1 AAAP01000019.1_1 - 0.023 15.0 0.8 0.025 14.8 0.8 1.2 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GATase_7 PF13537.6 AAAP01000020.1_1 - 1e-35 122.3 0.0 1.2e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01000020.1_1 - 6.9e-29 100.8 0.0 8.4e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AAAP01000020.1_1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein Big_9 PF17963.1 AAAP01000021.1_1 - 2.1e-08 34.8 15.3 5.9e-07 30.1 6.6 3.1 3 0 0 3 3 3 2 Bacterial Ig domain fn3 PF00041.21 AAAP01000021.1_1 - 3e-06 27.5 0.1 1e-05 25.8 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III domain Cadherin_5 PF17892.1 AAAP01000021.1_1 - 0.00019 21.4 4.9 0.001 19.0 0.2 2.9 2 1 1 3 3 3 1 Cadherin-like domain Tissue_fac PF01108.17 AAAP01000021.1_1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Tissue factor Cadherin_4 PF17803.1 AAAP01000021.1_1 - 8.5 7.1 17.3 1.5 9.5 10.1 3.0 2 1 1 3 3 3 0 Bacterial cadherin-like domain Sugarporin_N PF11471.8 AAAP01000022.1_1 - 0.013 15.4 0.3 0.019 14.9 0.3 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension MobB PF03205.14 AAAP01000023.1_1 - 1.4e-07 31.5 0.0 1.7e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 AAAP01000023.1_1 - 0.0082 16.2 0.2 0.01 15.9 0.2 1.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 AAAP01000023.1_1 - 0.013 14.5 0.0 0.014 14.4 0.0 1.0 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AAAP01000023.1_1 - 0.035 13.7 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AAAP01000023.1_1 - 0.041 13.8 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AAAP01000023.1_1 - 0.053 13.7 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAAP01000023.1_1 - 0.054 13.2 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 AAAP01000023.1_1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 AAAP01000023.1_1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 AAAP01000023.1_1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 AAAP01000023.1_1 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AAAP01000023.1_1 - 0.31 8.5 0.0 0.38 8.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliM PF02154.15 AAAP01000024.1_2 - 0.016 15.1 0.0 0.021 14.7 0.0 1.0 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Ribosomal_S2 PF00318.20 AAAP01000026.1_1 - 1.4e-51 174.8 0.0 1.8e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Glycos_transf_2 PF00535.26 AAAP01000027.1_1 - 0.019 14.8 0.0 0.02 14.7 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 HPP PF04982.13 AAAP01000027.1_2 - 4.4e-14 52.7 6.2 4.8e-14 52.6 2.9 2.1 2 0 0 2 2 2 1 HPP family DUF4191 PF13829.6 AAAP01000027.1_2 - 0.02 14.2 2.7 0.053 12.8 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4118 PF13493.6 AAAP01000027.1_2 - 2.4 8.0 7.3 0.34 10.7 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) Peptidase_S24 PF00717.23 AAAP01000028.1_1 - 1.5e-08 34.5 0.0 2.2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Cupin_2 PF07883.11 AAAP01000029.1_2 - 5.4e-07 29.2 0.0 6.1e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Cupin domain DDE_Tnp_Tn3 PF01526.17 AAAP01000030.1_1 - 3.8e-07 29.2 0.1 3.8e-07 29.2 0.1 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain FANC_SAP PF18081.1 AAAP01000030.1_1 - 0.089 13.0 0.5 0.11 12.6 0.5 1.2 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain ADH_zinc_N PF00107.26 AAAP01000035.1_1 - 7.9e-25 87.3 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01000035.1_1 - 3.9e-10 39.6 0.0 7.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 AAAP01000035.1_1 - 0.2 11.1 0.2 0.28 10.6 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Flagellin_N PF00669.20 AAAP01000036.1_1 - 5.4e-05 23.3 4.7 5.4e-05 23.3 4.7 2.0 1 1 1 2 2 2 1 Bacterial flagellin N-terminal helical region RHH_6 PF16762.5 AAAP01000036.1_1 - 0.029 15.0 0.1 0.086 13.5 0.1 1.9 1 1 0 1 1 1 0 Ribbon-helix-helix domain Alanine_zipper PF11839.8 AAAP01000036.1_1 - 1.5 9.2 6.4 0.62 10.5 0.5 2.2 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein HA2 PF04408.23 AAAP01000040.1_1 - 0.00018 21.7 0.1 0.00019 21.7 0.1 1.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) ResB PF05140.14 AAAP01000043.1_1 - 7.5e-09 34.8 0.0 9.1e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 ResB-like family Cytochrom_C_asm PF01578.20 AAAP01000043.1_2 - 2.8e-08 33.8 4.3 2.8e-08 33.8 4.3 2.5 2 1 1 3 3 3 1 Cytochrome C assembly protein Ala_racemase_N PF01168.20 AAAP01000045.1_1 - 1.5e-18 67.3 0.1 1.6e-18 67.2 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PseudoU_synth_2 PF00849.22 AAAP01000045.1_2 - 2.6e-06 27.6 0.0 3.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase GntR PF00392.21 AAAP01000047.1_1 - 1.8e-10 40.3 0.9 4e-10 39.2 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 AAAP01000047.1_1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_Crp_2 PF13545.6 AAAP01000047.1_1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_50 PF18024.1 AAAP01000047.1_1 - 0.054 13.1 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01000047.1_1 - 0.07 12.7 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AMP-binding PF00501.28 AAAP01000048.1_1 - 1.4e-06 27.2 0.6 1.6e-06 27.0 0.6 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 AAAP01000048.1_2 - 1.2e-10 40.6 0.0 1.3e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF192 PF02643.15 AAAP01000049.1_1 - 1.9e-17 63.2 0.0 2.1e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Molydop_binding PF01568.21 AAAP01000049.1_1 - 0.0037 17.3 0.0 0.0053 16.8 0.0 1.3 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain DUF1905 PF08922.11 AAAP01000049.1_1 - 0.014 15.5 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) MCM PF00493.23 AAAP01000049.1_2 - 0.0096 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain DUF218 PF02698.17 AAAP01000051.1_2 - 8.9e-13 48.4 0.0 9.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain TrkA_C PF02080.21 AAAP01000052.1_1 - 9.4e-08 31.8 0.0 1.1e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 TrkA-C domain CCG PF02754.16 AAAP01000053.1_1 - 0.0072 16.5 0.1 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 Cysteine-rich domain PAS_3 PF08447.12 AAAP01000054.1_1 - 6.6e-11 42.3 0.0 1.7e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01000054.1_1 - 1.2e-05 25.5 0.8 0.00014 22.0 0.1 2.5 2 1 1 3 3 3 1 PAS fold KinB_sensor PF16767.5 AAAP01000054.1_1 - 0.04 14.4 0.5 0.079 13.4 0.5 1.4 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB CM_1 PF07736.11 AAAP01000055.1_1 - 1.1e-17 64.5 0.0 1.2e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate mutase type I Cytidylate_kin PF02224.18 AAAP01000055.1_2 - 1.2e-42 146.0 0.2 1.9e-42 145.4 0.2 1.3 1 1 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AAAP01000055.1_2 - 5.9e-06 26.5 1.2 4.4e-05 23.7 1.2 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AAAP01000055.1_2 - 0.00022 21.8 0.0 0.0034 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01000055.1_2 - 0.00043 20.4 3.2 0.0059 16.8 3.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAAP01000055.1_2 - 0.0025 18.2 0.1 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 AAAP01000055.1_2 - 0.017 15.2 0.1 0.044 13.9 0.1 1.7 2 0 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.27 AAAP01000055.1_2 - 0.1 13.1 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter ADK PF00406.22 AAAP01000055.1_2 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase B5 PF03484.15 AAAP01000056.1_1 - 6.5e-15 55.2 0.5 1.9e-14 53.7 0.3 1.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA_synthFbeta PF17759.1 AAAP01000056.1_1 - 0.0001 21.8 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain VapB_antitoxin PF09957.9 AAAP01000056.1_1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Big_2 PF02368.18 AAAP01000058.1_1 - 0.0099 15.8 0.3 0.01 15.7 0.3 1.1 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 2) OprB PF04966.12 AAAP01000059.1_1 - 9.2e-35 120.8 0.0 1.2e-34 120.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Cons_hypoth698 PF03601.14 AAAP01000060.1_1 - 9.5e-38 129.8 18.3 1.1e-37 129.5 18.3 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 698 HlyIII PF03006.20 AAAP01000060.1_1 - 1.3 8.7 8.4 0.98 9.1 1.2 2.4 2 1 1 3 3 3 0 Haemolysin-III related AA_permease_2 PF13520.6 AAAP01000061.1_2 - 7.7e-08 31.6 6.3 1.3e-07 30.8 6.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF5326 PF17260.2 AAAP01000061.1_2 - 1.4 9.1 9.8 12 6.1 6.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DUF4191 PF13829.6 AAAP01000061.1_2 - 1.4 8.2 5.1 0.92 8.8 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3487 PF11990.8 AAAP01000061.1_2 - 5 7.0 7.6 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) FTR PF01913.18 AAAP01000062.1_1 - 1.9e-39 134.8 0.0 2.1e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase L71 PF02448.15 AAAP01000063.1_1 - 0.11 12.9 0.3 0.19 12.1 0.3 1.5 1 1 0 1 1 1 0 L71 family Lipase_GDSL_2 PF13472.6 AAAP01000063.1_2 - 4e-06 27.3 0.1 6.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 AAAP01000063.1_2 - 0.00065 19.9 0.0 0.00093 19.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family EAL PF00563.20 AAAP01000064.1_1 - 9.7e-16 58.0 0.0 1.1e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain Dus PF01207.17 AAAP01000064.1_2 - 6.1e-24 84.7 0.0 7.5e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAAP01000064.1_2 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein ACR_tran PF00873.19 AAAP01000067.1_1 - 1.8e-31 108.7 0.1 2.2e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family PTS_EIIA_2 PF00359.22 AAAP01000067.1_2 - 6e-08 32.7 0.1 1.8e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Nif11 PF07862.11 AAAP01000067.1_2 - 0.026 14.8 0.1 0.059 13.7 0.1 1.6 1 0 0 1 1 1 0 Nif11 domain Abhydrolase_4 PF08386.10 AAAP01000069.1_1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Abhydrolase_1 PF00561.20 AAAP01000069.1_1 - 0.02 14.6 0.0 2.2 7.8 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAAP01000069.1_1 - 0.023 14.2 0.5 0.058 12.9 0.2 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 AAAP01000069.1_1 - 0.069 12.7 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 AAAP01000069.1_1 - 0.088 12.6 0.2 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 AAAP01000069.1_1 - 0.26 11.1 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family MeaB PF03308.16 AAAP01000070.1_1 - 3.4e-107 357.4 1.1 3.9e-107 357.2 1.1 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AAAP01000070.1_1 - 9.4e-06 25.3 1.0 0.00011 21.8 1.0 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AAAP01000070.1_1 - 3.9e-05 23.5 0.4 9.7e-05 22.2 0.4 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01000070.1_1 - 0.00019 21.5 0.0 0.0004 20.4 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 AAAP01000070.1_1 - 0.00023 20.9 0.4 0.00063 19.4 0.4 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 AAAP01000070.1_1 - 0.00042 20.0 0.6 0.0026 17.4 0.6 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 AAAP01000070.1_1 - 0.0012 19.4 0.2 0.0041 17.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 AAAP01000070.1_1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase ATP_bind_1 PF03029.17 AAAP01000070.1_1 - 0.0015 18.4 0.2 0.0024 17.7 0.2 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 AAAP01000070.1_1 - 0.0025 17.8 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01000070.1_1 - 0.0031 17.6 0.2 0.013 15.5 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 AAAP01000070.1_1 - 0.0034 17.3 0.3 0.0064 16.4 0.3 1.5 1 0 0 1 1 1 1 NTPase Fer4_NifH PF00142.18 AAAP01000070.1_1 - 0.0054 16.2 0.1 0.008 15.6 0.1 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 AAAP01000070.1_1 - 0.006 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01000070.1_1 - 0.0098 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 AAAP01000070.1_1 - 0.011 15.3 0.0 2.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ArsA_ATPase PF02374.15 AAAP01000070.1_1 - 0.011 14.9 1.7 0.02 14.1 1.7 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_28 PF13521.6 AAAP01000070.1_1 - 0.024 14.9 0.3 0.42 10.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain ParA PF10609.9 AAAP01000070.1_1 - 0.034 13.6 2.1 0.079 12.4 0.6 2.0 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase KTI12 PF08433.10 AAAP01000070.1_1 - 0.045 13.2 0.1 0.091 12.2 0.0 1.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 AAAP01000070.1_1 - 0.05 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AAAP01000070.1_1 - 0.093 13.2 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 ABC transporter CTP_synth_N PF06418.14 AAAP01000070.1_1 - 0.15 11.3 0.3 0.25 10.6 0.3 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus ACR_tran PF00873.19 AAAP01000071.1_1 - 2.9e-55 187.5 0.0 3.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family TonB_dep_Rec PF00593.24 AAAP01000072.1_1 - 5.6e-08 33.1 1.3 5.6e-08 33.1 1.3 1.0 1 0 0 1 1 1 1 TonB dependent receptor CENP-F_leu_zip PF10473.9 AAAP01000073.1_1 - 0.028 14.5 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 AAAP01000073.1_1 - 0.16 10.2 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 AAAP01000073.1_1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 AAAP01000073.1_1 - 0.83 9.7 9.8 0.057 13.5 2.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 AAAP01000073.1_1 - 2 8.2 10.0 0.14 11.9 4.4 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SBP_bac_3 PF00497.20 AAAP01000073.1_1 - 6.9 6.0 11.3 0.26 10.7 3.1 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 DUF3584 PF12128.8 AAAP01000073.1_1 - 8.7 3.7 13.1 14 3.0 13.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Cys_Met_Meta_PP PF01053.20 AAAP01000073.1_2 - 1.9e-06 26.7 0.0 2e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DNA_pol3_alpha PF07733.12 AAAP01000074.1_1 - 1.5e-16 60.8 0.0 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAAP01000074.1_1 - 9.2e-08 31.6 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain Transp_cyt_pur PF02133.15 AAAP01000075.1_1 - 5e-25 88.2 14.5 5.7e-25 88.0 14.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 AAAP01000075.1_2 - 8.7e-11 41.2 1.2 9.9e-11 41.1 1.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NADHdh PF00146.21 AAAP01000076.1_1 - 2.2e-54 184.8 6.2 2.6e-54 184.6 6.2 1.0 1 0 0 1 1 1 1 NADH dehydrogenase DUF3464 PF11947.8 AAAP01000076.1_1 - 0.06 13.1 3.4 0.094 12.5 3.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RimM PF01782.18 AAAP01000077.1_1 - 1.8e-17 63.3 0.0 2.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RimM N-terminal domain HlyD_3 PF13437.6 AAAP01000078.1_1 - 2.7e-12 47.3 3.2 2.8e-07 31.2 0.0 3.3 3 1 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01000078.1_1 - 2.5e-08 33.4 1.8 4.9e-06 25.9 0.0 3.2 1 1 2 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion MerR-DNA-bind PF09278.11 AAAP01000078.1_1 - 0.013 16.1 1.8 0.013 16.1 1.8 3.2 4 0 0 4 4 4 0 MerR, DNA binding Atg14 PF10186.9 AAAP01000078.1_1 - 0.08 12.0 7.4 0.022 13.8 4.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 AAAP01000078.1_1 - 0.95 9.0 8.5 2.8 7.4 8.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 AAAP01000078.1_1 - 3.2 6.5 9.4 0.16 10.8 3.0 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein LysR_substrate PF03466.20 AAAP01000080.1_1 - 2.6e-20 72.7 0.4 3.9e-20 72.1 0.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01000080.1_1 - 8.7e-18 64.0 0.4 1.8e-17 63.0 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAAP01000080.1_1 - 0.052 13.6 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 AAAP01000080.1_1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Epimerase PF01370.21 AAAP01000081.1_2 - 9.4e-33 113.7 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01000081.1_2 - 3.9e-21 75.8 0.0 1.6e-19 70.5 0.0 2.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01000081.1_2 - 0.0002 20.6 0.0 0.00098 18.3 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAAP01000081.1_2 - 0.0061 16.5 3.2 0.16 11.8 2.8 2.3 1 1 1 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AAAP01000081.1_2 - 0.012 14.7 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AAAP01000081.1_2 - 0.044 13.2 1.0 0.093 12.2 0.2 1.9 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 AAAP01000081.1_2 - 0.047 13.2 0.4 0.067 12.7 0.4 1.2 1 0 0 1 1 1 0 NmrA-like family TAT_signal PF10518.9 AAAP01000081.1_2 - 0.11 12.4 0.2 0.11 12.4 0.2 2.9 4 0 0 4 4 4 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AAAP01000081.1_2 - 2.9 7.3 8.6 0.12 11.7 0.7 2.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CN_hydrolase PF00795.22 AAAP01000083.1_1 - 9.3e-30 103.8 0.0 1.1e-29 103.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF5130 PF17174.4 AAAP01000083.1_2 - 0.026 14.7 0.0 0.029 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) GerE PF00196.19 AAAP01000084.1_1 - 3.6e-16 58.5 0.4 6.1e-16 57.7 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01000084.1_1 - 6.4e-06 25.7 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Response_reg PF00072.24 AAAP01000084.1_1 - 0.00016 21.8 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain DUF5441 PF17513.2 AAAP01000084.1_1 - 0.04 13.6 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5441) LexA_DNA_bind PF01726.16 AAAP01000084.1_1 - 0.057 13.2 0.3 1 9.2 0.1 2.6 2 1 0 2 2 2 0 LexA DNA binding domain HTH_38 PF13936.6 AAAP01000084.1_1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01000084.1_1 - 0.12 11.9 0.3 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAAP01000084.1_1 - 0.16 11.5 1.5 0.22 11.1 0.2 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 GSDH PF07995.11 AAAP01000085.1_1 - 1.8e-13 50.5 0.2 1.4e-11 44.3 0.3 2.9 2 2 0 2 2 2 2 Glucose / Sorbosone dehydrogenase NUDIX PF00293.28 AAAP01000086.1_1 - 6.6e-06 26.2 0.2 8.2e-06 25.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain FabA PF07977.13 AAAP01000087.1_2 - 4.3e-18 65.3 0.0 5.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain AfsA PF03756.13 AAAP01000087.1_2 - 5.5e-05 23.2 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 A-factor biosynthesis hotdog domain PP-binding PF00550.25 AAAP01000087.1_3 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphopantetheine attachment site Gly_kinase PF02595.15 AAAP01000089.1_1 - 0.013 14.5 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Glycerate kinase family MarR_2 PF12802.7 AAAP01000089.1_2 - 7.3e-14 51.4 3.0 9.6e-14 51.0 0.2 2.2 2 1 0 2 2 2 1 MarR family MarR PF01047.22 AAAP01000089.1_2 - 3e-10 39.9 0.0 6.1e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAAP01000089.1_2 - 4.3e-10 39.9 0.1 2.4e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AAAP01000089.1_2 - 0.0036 17.1 2.0 0.0036 17.1 0.1 2.0 3 0 0 3 3 3 1 IclR helix-turn-helix domain HxlR PF01638.17 AAAP01000089.1_2 - 0.004 17.0 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 AAAP01000089.1_2 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 AAAP01000089.1_2 - 0.057 13.6 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_1 PF00126.27 AAAP01000089.1_2 - 0.097 12.6 1.0 0.36 10.8 1.0 2.0 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 AAAP01000089.1_2 - 0.18 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain PTE PF02126.18 AAAP01000090.1_1 - 1.5e-25 90.3 0.0 1.9e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family PAS_4 PF08448.10 AAAP01000091.1_1 - 2.3e-11 43.9 0.1 2.8e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01000091.1_1 - 0.18 12.1 0.0 0.23 11.7 0.0 1.1 1 0 0 1 1 1 0 PAS domain CHAP PF05257.16 AAAP01000093.1_2 - 6.5e-06 26.6 0.6 1.2e-05 25.8 0.6 1.4 1 0 0 1 1 1 1 CHAP domain NLPC_P60 PF00877.19 AAAP01000093.1_2 - 0.0014 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family UvrD_C PF13361.6 AAAP01000094.1_1 - 8.2e-24 84.6 0.0 8.1e-15 55.0 0.0 2.0 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AAAP01000094.1_1 - 9.5e-06 25.3 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 AAAP01000094.1_1 - 0.003 17.4 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain CN_hydrolase PF00795.22 AAAP01000095.1_1 - 1.9e-38 132.3 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pantoate_ligase PF02569.15 AAAP01000097.1_1 - 1.7e-07 30.7 0.0 1.7e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase SPASM PF13186.6 AAAP01000099.1_1 - 0.00061 20.2 0.5 0.0011 19.4 0.5 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain DUF3716 PF12511.8 AAAP01000099.1_1 - 0.074 13.1 1.3 0.074 13.1 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Caa3_CtaG PF09678.10 AAAP01000101.1_1 - 4.8e-08 32.8 2.0 5.5e-08 32.5 2.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF3459 PF11941.8 AAAP01000104.1_1 - 2.6e-05 24.4 0.1 2.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) SBP_bac_1 PF01547.25 AAAP01000104.1_2 - 2e-06 28.0 0.4 2.5e-06 27.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Radical_SAM PF04055.21 AAAP01000105.1_1 - 3.7e-15 56.7 0.0 7.6e-15 55.7 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01000105.1_1 - 6.8e-10 39.0 0.3 7.2e-08 32.5 0.1 2.4 2 1 0 2 2 2 2 B12 binding domain Fer4_12 PF13353.6 AAAP01000105.1_1 - 0.2 11.9 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain FGase PF05013.12 AAAP01000106.1_1 - 1.8e-44 152.5 0.2 2.1e-44 152.3 0.2 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase TPR_16 PF13432.6 AAAP01000107.1_1 - 7.9e-07 29.6 1.1 1.2e-06 29.0 1.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01000107.1_1 - 1.1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01000107.1_1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01000107.1_1 - 0.0059 17.1 1.8 0.0059 17.1 1.8 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01000107.1_1 - 0.0094 16.7 2.6 0.092 13.6 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01000107.1_1 - 0.045 13.9 0.0 8.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Aconitase PF00330.20 AAAP01000108.1_1 - 1.1e-26 93.9 0.2 1.2e-26 93.8 0.2 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) NAD_binding_2 PF03446.15 AAAP01000109.1_2 - 2e-22 80.0 0.1 3.5e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01000109.1_2 - 1.6e-11 44.7 0.1 3.2e-11 43.7 0.1 1.6 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AAAP01000109.1_2 - 1.6e-06 28.3 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01000109.1_2 - 2.4e-05 23.8 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AAAP01000109.1_2 - 3.7e-05 23.4 0.1 0.00013 21.7 0.1 1.9 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 AAAP01000109.1_2 - 0.00013 22.2 0.0 0.0005 20.3 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AAAP01000109.1_2 - 0.0016 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 AAAP01000109.1_2 - 0.0059 16.5 0.5 0.014 15.3 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAAP01000109.1_2 - 0.0073 16.3 0.8 0.069 13.1 0.0 2.5 2 1 1 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YAcAr PF10686.9 AAAP01000109.1_2 - 0.012 15.6 1.9 0.017 15.0 0.2 2.1 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family NAD_binding_7 PF13241.6 AAAP01000109.1_2 - 0.019 15.4 0.1 0.042 14.3 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 AAAP01000109.1_2 - 0.054 14.0 0.2 0.13 12.7 0.2 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain GerE PF00196.19 AAAP01000110.1_2 - 5.9e-06 25.7 0.0 7.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01000110.1_2 - 0.0027 17.4 0.0 0.0086 15.7 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AAAP01000110.1_2 - 0.005 16.2 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AAAP01000110.1_2 - 0.0079 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AAAP01000110.1_2 - 0.017 14.6 0.2 0.061 12.9 0.1 2.0 2 1 0 2 2 2 0 Sigma-70, region 4 tRNA_synt_2f PF02092.17 AAAP01000111.1_1 - 3.1e-77 260.7 0.0 3.6e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit POLO_box PF00659.18 AAAP01000112.1_1 - 0.17 12.1 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 POLO box duplicated region rve_3 PF13683.6 AAAP01000112.1_2 - 1.5e-16 59.9 0.0 2.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01000112.1_2 - 0.033 14.4 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain CBP_GIL PF10995.8 AAAP01000112.1_2 - 0.047 12.4 0.0 0.054 12.2 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis GIL ATP-synt_B PF00430.18 AAAP01000113.1_2 - 1.2e-14 54.5 6.9 1.6e-14 54.1 6.9 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 AAAP01000113.1_2 - 9.9e-07 28.5 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DivIVA PF05103.13 AAAP01000113.1_2 - 0.019 15.0 6.8 0.029 14.5 6.8 1.3 1 1 0 1 1 1 0 DivIVA protein DUF2894 PF11445.8 AAAP01000113.1_2 - 0.084 13.3 3.7 0.1 13.1 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) UXS1_N PF11803.8 AAAP01000113.1_2 - 0.089 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal Trypan_glycop PF00913.19 AAAP01000113.1_2 - 0.79 8.9 4.3 1 8.6 4.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) HemY_N PF07219.13 AAAP01000113.1_2 - 1.3 9.3 8.2 2.5 8.3 8.2 1.6 1 1 0 1 1 1 0 HemY protein N-terminus SBP_bac_5 PF00496.22 AAAP01000114.1_1 - 7.2e-35 120.6 0.0 8.5e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_5 PF00496.22 AAAP01000114.1_2 - 2.1e-05 23.6 0.3 2.1e-05 23.6 0.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle GSDH PF07995.11 AAAP01000116.1_1 - 5.7e-07 29.2 0.0 7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF4179 PF13786.6 AAAP01000116.1_1 - 0.039 14.4 0.0 0.045 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Pro_dh PF01619.18 AAAP01000117.1_1 - 2e-17 63.7 0.0 2.2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 AAAP01000117.1_1 - 0.00067 19.2 0.1 0.00091 18.7 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Catalase PF00199.19 AAAP01000119.1_1 - 5.7e-18 65.2 0.3 5.7e-18 65.2 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase PF00199.19 AAAP01000119.1_2 - 3e-77 260.3 0.1 3.3e-77 260.2 0.1 1.0 1 0 0 1 1 1 1 Catalase B12-binding PF02310.19 AAAP01000120.1_1 - 7.1e-19 68.0 0.4 1.2e-18 67.3 0.4 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AAAP01000120.1_1 - 0.0018 18.7 0.5 0.0041 17.5 0.1 1.9 2 0 0 2 2 2 1 B12 binding domain Met_synt_B12 PF02965.17 AAAP01000120.1_1 - 0.12 11.8 0.1 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain YjbR PF04237.13 AAAP01000121.1_2 - 1.9e-08 34.8 0.0 2.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 YjbR Aldo_ket_red PF00248.21 AAAP01000121.1_3 - 0.00011 21.5 0.0 0.00014 21.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tail_VII PF17091.5 AAAP01000121.1_3 - 0.087 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Inovirus G7P protein GTP_EFTU PF00009.27 AAAP01000122.1_1 - 4.5e-48 163.4 0.0 5.4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAAP01000122.1_1 - 3.1e-06 27.2 0.0 7.4e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 AAAP01000122.1_1 - 0.028 13.9 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.10 AAAP01000122.1_1 - 0.1 12.0 0.0 0.61 9.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AAAP01000122.1_1 - 0.12 12.6 0.0 0.76 10.0 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AAAP01000122.1_1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Ras family TonB_dep_Rec PF00593.24 AAAP01000123.1_1 - 3.8e-13 50.1 1.1 4.1e-13 50.0 1.1 1.0 1 0 0 1 1 1 1 TonB dependent receptor HGTP_anticodon PF03129.20 AAAP01000124.1_1 - 1.6e-22 79.5 0.0 3.2e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AAAP01000124.1_1 - 1.7e-08 34.6 0.0 4.1e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ENT PF03735.14 AAAP01000124.1_1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 ENT domain Peptidase_M3 PF01432.20 AAAP01000125.1_1 - 4.3e-70 237.3 0.0 4.7e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 AAAP01000125.1_1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like FTHFS PF01268.19 AAAP01000125.1_2 - 1.7e-31 109.1 0.0 1.9e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Inhibitor_I78 PF11720.8 AAAP01000125.1_2 - 0.076 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I78 family UvrD_C_2 PF13538.6 AAAP01000126.1_2 - 1.4e-07 31.2 0.5 1.4e-07 31.2 0.5 1.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain SNF2_N PF00176.23 AAAP01000127.1_1 - 7.4e-11 41.4 0.0 9.1e-11 41.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 AAAP01000127.1_1 - 3.1e-06 27.3 0.0 9.2e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AAAP01000127.1_1 - 2.2e-05 24.3 0.0 3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 AAAP01000127.1_1 - 0.041 14.3 0.0 10 6.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hexapep PF00132.24 AAAP01000128.1_1 - 1.3e-14 53.3 7.9 3.9e-11 42.2 2.9 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01000128.1_1 - 2.8e-14 52.5 5.1 1.5e-09 37.5 2.0 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Peptidase_M50 PF02163.22 AAAP01000129.1_1 - 2e-05 24.0 1.1 2.5e-05 23.7 1.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 Acyl_transf_3 PF01757.22 AAAP01000129.1_1 - 0.0042 16.2 3.5 0.0045 16.1 3.5 1.1 1 0 0 1 1 1 1 Acyltransferase family Colicin_V PF02674.16 AAAP01000129.1_1 - 0.0061 16.5 3.7 0.0071 16.3 3.7 1.1 1 0 0 1 1 1 1 Colicin V production protein Peptidase_M50B PF13398.6 AAAP01000129.1_1 - 0.085 12.5 5.9 0.13 11.8 5.2 1.7 1 1 1 2 2 2 0 Peptidase M50B-like DUF4344 PF14247.6 AAAP01000129.1_1 - 0.18 11.4 0.2 0.25 11.0 0.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase Tad PF13400.6 AAAP01000129.1_1 - 3.6 8.0 8.5 0.17 12.2 1.6 2.0 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like HAD_2 PF13419.6 AAAP01000129.1_2 - 7.7e-30 104.3 0.0 8.9e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01000129.1_2 - 5.7e-20 72.5 0.1 2.4e-19 70.4 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01000129.1_2 - 5.2e-10 40.0 0.1 1e-09 39.1 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01000129.1_2 - 3.2e-07 30.3 0.0 8.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAAP01000129.1_2 - 0.052 13.7 0.0 2 8.6 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Peripla_BP_6 PF13458.6 AAAP01000129.1_2 - 0.062 12.9 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Glyoxalase_2 PF12681.7 AAAP01000130.1_2 - 3.8e-07 30.0 0.0 4.6e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 AAAP01000130.1_2 - 9.5e-07 29.1 0.0 1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01000130.1_2 - 3.5e-05 24.6 0.1 4.4e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Ribosomal_L12 PF00542.19 AAAP01000131.1_1 - 1.1e-30 105.8 10.3 1.1e-30 105.8 10.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AAAP01000131.1_1 - 6.8e-19 67.3 15.7 1e-17 63.5 12.7 2.6 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain HWE_HK PF07536.14 AAAP01000132.1_1 - 2.6e-10 40.9 0.1 2.6e-10 40.8 0.1 1.0 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 AAAP01000132.1_2 - 9.7e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold HWE_HK PF07536.14 AAAP01000132.1_2 - 1.9e-09 38.1 0.3 4.6e-09 36.9 0.3 1.6 1 0 0 1 1 1 1 HWE histidine kinase PAS_4 PF08448.10 AAAP01000132.1_2 - 2.1e-05 24.7 0.5 3.6e-05 24.0 0.4 1.5 1 1 0 1 1 1 1 PAS fold HisKA_2 PF07568.12 AAAP01000132.1_2 - 0.0002 21.4 0.6 0.00037 20.5 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase DUF2267 PF10025.9 AAAP01000132.1_2 - 0.26 11.6 2.7 0.34 11.2 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Helicase_C PF00271.31 AAAP01000133.1_1 - 3.4e-16 59.6 0.0 6.9e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 AAAP01000133.1_1 - 1.3e-15 57.9 4.6 3.8e-15 56.4 4.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 AAAP01000133.1_1 - 8.6e-14 51.3 0.0 1.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RQC domain LYRIC PF15686.5 AAAP01000133.1_1 - 0.31 10.6 8.2 0.45 10.0 8.2 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family MaoC_dehydratas PF01575.19 AAAP01000134.1_1 - 7.7e-13 48.1 0.1 8.2e-06 25.4 0.1 2.4 2 0 0 2 2 2 2 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01000134.1_1 - 2.8e-05 24.3 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase GrpE PF01025.19 AAAP01000135.1_1 - 4.6e-34 117.5 0.0 6.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 GrpE GerE PF00196.19 AAAP01000136.1_1 - 2.1e-10 40.0 0.0 2.5e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01000136.1_1 - 0.034 13.8 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 SurE PF01975.17 AAAP01000137.1_1 - 4.5e-09 36.4 0.0 5.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE PCMT PF01135.19 AAAP01000137.1_2 - 1.5e-08 34.7 0.0 1.7e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3530 PF12048.8 AAAP01000138.1_1 - 0.0023 17.4 0.2 0.0026 17.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Peptidase_S9 PF00326.21 AAAP01000138.1_2 - 0.0024 17.4 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Xan_ur_permease PF00860.20 AAAP01000139.1_1 - 2.4e-17 62.7 19.3 2.4e-17 62.7 19.3 1.4 1 1 1 2 2 2 1 Permease family ACR_tran PF00873.19 AAAP01000140.1_1 - 1.3e-44 152.2 0.4 1.4e-44 152.1 0.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family OMP_b-brl PF13505.6 AAAP01000141.1_2 - 7.5e-19 68.5 0.5 1e-18 68.1 0.5 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 AAAP01000141.1_2 - 9.9e-06 25.7 0.4 3.2e-05 24.0 0.3 2.0 1 1 0 1 1 1 1 Opacity family porin protein Surface_Ag_2 PF01617.17 AAAP01000141.1_2 - 0.013 15.0 1.6 0.52 9.7 0.9 2.7 2 1 0 2 2 2 0 Surface antigen DUF2490 PF10677.9 AAAP01000141.1_2 - 0.17 11.8 0.1 3.1 7.7 0.0 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2490) CSD PF00313.22 AAAP01000142.1_2 - 7.8e-24 83.3 0.2 8.5e-24 83.2 0.2 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01000142.1_2 - 2.5e-05 23.9 0.2 3.3e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 AAAP01000142.1_2 - 0.0033 17.3 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain Abhydrolase_6 PF12697.7 AAAP01000143.1_1 - 9.4e-11 42.7 6.0 1.1e-10 42.6 6.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01000143.1_1 - 6.2e-07 29.3 0.1 8.1e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01000143.1_1 - 5.1e-06 25.9 0.0 5.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 AAAP01000143.1_1 - 0.0032 17.1 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 AAAP01000143.1_1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 AAAP01000143.1_1 - 0.18 11.5 0.0 0.65 9.7 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein AA_kinase PF00696.28 AAAP01000143.1_2 - 6.6e-16 58.6 0.2 8.1e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family tRNA-synt_2b PF00587.25 AAAP01000144.1_1 - 4.2e-19 69.2 0.0 6.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AAAP01000144.1_1 - 4.5e-16 59.0 0.4 7e-16 58.4 0.4 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF349 PF03993.12 AAAP01000144.1_1 - 0.13 12.6 6.8 0.26 11.6 6.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) LPP PF04728.13 AAAP01000144.1_1 - 4.7 7.7 6.3 4.9 7.6 2.5 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper NAD_binding_8 PF13450.6 AAAP01000145.1_2 - 7.2e-06 26.2 0.1 8.9e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAAP01000145.1_2 - 5.8e-05 22.5 0.1 6.5e-05 22.3 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01000145.1_2 - 0.00022 20.5 0.0 0.00023 20.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01000145.1_2 - 0.00033 19.9 0.1 0.00035 19.8 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAAP01000145.1_2 - 0.00044 19.6 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAAP01000145.1_2 - 0.002 17.4 0.0 0.0021 17.3 0.0 1.0 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AAAP01000145.1_2 - 0.0021 18.6 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01000145.1_2 - 0.0026 16.5 0.0 0.0027 16.5 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 AAAP01000145.1_2 - 0.0036 17.0 0.1 0.0038 16.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 AAAP01000145.1_2 - 0.0062 15.7 0.1 0.0066 15.6 0.1 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 AAAP01000145.1_2 - 0.017 14.6 0.0 0.017 14.6 0.0 1.0 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 AAAP01000145.1_2 - 0.029 14.8 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AAAP01000145.1_2 - 0.13 11.6 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAAP01000145.1_2 - 0.16 11.5 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Col_cuticle_N PF01484.17 AAAP01000147.1_2 - 0.021 14.9 0.3 0.03 14.4 0.3 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain MFS_1 PF07690.16 AAAP01000149.1_1 - 1.3e-09 37.5 24.9 1.8e-09 37.0 24.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.21 AAAP01000149.1_1 - 0.0012 18.6 5.2 0.0019 18.0 5.2 1.2 1 0 0 1 1 1 1 Cation efflux family Peripla_BP_2 PF01497.18 AAAP01000150.1_1 - 1.4e-07 31.3 0.9 2.3e-07 30.6 0.9 1.3 1 0 0 1 1 1 1 Periplasmic binding protein LPAM_2 PF13627.6 AAAP01000150.1_1 - 0.29 11.1 5.2 0.52 10.2 5.2 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Pyridoxal_deC PF00282.19 AAAP01000151.1_1 - 7e-20 71.1 0.0 5.2e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 AAAP01000151.1_1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HigB-like_toxin PF05015.13 AAAP01000152.1_1 - 7.1e-17 61.6 0.0 8.2e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB DUF1134 PF06577.12 AAAP01000154.1_1 - 2.3e-16 60.0 0.4 2.7e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1134) LapA_dom PF06305.11 AAAP01000154.1_2 - 0.15 11.9 0.8 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PALP PF00291.25 AAAP01000155.1_1 - 4.7e-37 128.0 0.0 5.4e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PilZ PF07238.14 AAAP01000155.1_2 - 9.3e-05 22.7 0.2 0.00025 21.3 0.2 1.7 1 1 0 1 1 1 1 PilZ domain LSM PF01423.22 AAAP01000155.1_2 - 0.069 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 LSM domain YdjC PF04794.12 AAAP01000156.1_1 - 0.00064 19.8 0.0 0.00067 19.7 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein MMPL PF03176.15 AAAP01000156.1_2 - 0.019 13.9 12.8 0.033 13.1 12.8 1.5 1 1 0 1 1 1 0 MMPL family Folate_carrier PF01770.18 AAAP01000156.1_2 - 0.04 12.7 0.5 0.047 12.4 0.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier UPF0640 PF15114.6 AAAP01000156.1_2 - 0.35 10.7 1.3 2.4 8.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 CcmF_C PF16327.5 AAAP01000156.1_2 - 0.99 8.6 6.4 1.1 8.5 6.4 1.0 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF3464 PF11947.8 AAAP01000156.1_2 - 1.7 8.4 4.4 2.1 8.1 4.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CPP1-like PF11833.8 AAAP01000156.1_2 - 2.2 7.9 7.3 2.4 7.8 7.3 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HTH_1 PF00126.27 AAAP01000157.1_1 - 0.0074 16.2 0.2 3.5 7.6 0.0 2.6 1 1 1 2 2 2 2 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAAP01000157.1_1 - 0.067 13.3 1.8 10 6.4 0.1 3.0 2 1 1 3 3 3 0 Helix-turn-helix domain PGI PF00342.19 AAAP01000158.1_1 - 8.6e-92 308.2 0.0 1.1e-91 307.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase ZnuA PF01297.17 AAAP01000159.1_1 - 3.4e-23 82.4 0.0 3.9e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic ABC_tran PF00005.27 AAAP01000159.1_2 - 4.2e-11 43.5 0.0 7.1e-11 42.8 0.0 1.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 AAAP01000159.1_2 - 0.00025 20.7 0.3 0.00042 20.0 0.3 1.5 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01000159.1_2 - 0.003 17.4 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 AAAP01000159.1_2 - 0.0036 16.5 0.3 0.0042 16.3 0.3 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 AAAP01000159.1_2 - 0.0046 17.5 0.2 0.0052 17.3 0.2 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01000159.1_2 - 0.0071 15.8 0.0 0.0075 15.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain MeaB PF03308.16 AAAP01000159.1_2 - 0.019 14.0 0.5 0.022 13.8 0.5 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 AAAP01000159.1_2 - 0.02 14.6 0.3 0.024 14.4 0.3 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01000159.1_2 - 0.021 14.9 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAAP01000159.1_2 - 0.029 14.5 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01000159.1_2 - 0.042 14.2 0.1 0.046 14.1 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 AAAP01000159.1_2 - 0.14 11.9 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MukB PF04310.12 AAAP01000159.1_2 - 0.2 11.4 0.1 0.25 11.1 0.1 1.1 1 0 0 1 1 1 0 MukB N-terminal TonB_dep_Rec PF00593.24 AAAP01000160.1_1 - 6e-22 79.2 5.7 7.4e-22 78.9 5.7 1.0 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AAAP01000160.1_1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.4 1 1 0 1 1 1 0 Outer membrane protein beta-barrel family AIRS_C PF02769.22 AAAP01000161.1_1 - 0.067 13.3 0.1 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 AIR synthase related protein, C-terminal domain SMC_N PF02463.19 AAAP01000162.1_1 - 0.0026 17.2 0.0 0.0032 16.9 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAAP01000162.1_1 - 0.0077 16.1 0.2 0.0087 15.9 0.2 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAAP01000162.1_1 - 0.057 13.9 0.2 0.083 13.4 0.2 1.3 1 0 0 1 1 1 0 ABC transporter M20_dimer PF07687.14 AAAP01000162.1_2 - 3.1e-08 33.5 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 AAAP01000162.1_2 - 5e-05 23.1 0.1 0.00012 21.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DAO PF01266.24 AAAP01000164.1_1 - 2.1e-05 24.3 0.2 0.0094 15.6 0.1 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAAP01000164.1_1 - 0.00048 19.5 0.3 0.21 10.8 0.3 2.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01000164.1_1 - 0.00063 19.1 0.0 0.004 16.4 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAAP01000164.1_1 - 0.001 18.2 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 AAAP01000164.1_1 - 0.0043 15.8 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 AAAP01000164.1_1 - 0.0052 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAAP01000164.1_1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 AAAP01000164.1_1 - 0.025 13.9 0.1 0.051 12.8 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 AAAP01000164.1_1 - 0.041 13.1 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01000164.1_1 - 0.11 11.6 0.1 4.4 6.3 0.0 2.1 1 1 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 AAAP01000164.1_1 - 0.15 12.7 0.0 6.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Response_reg PF00072.24 AAAP01000165.1_2 - 2.1e-15 56.9 0.0 7.4e-14 51.9 0.0 2.0 2 0 0 2 2 2 2 Response regulator receiver domain UCR_Fe-S_N PF10399.9 AAAP01000166.1_1 - 1.1 8.6 6.1 5.3 6.5 3.9 2.0 1 1 1 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ASRT PF07100.11 AAAP01000167.1_1 - 2.6e-10 40.4 0.3 2.8e-10 40.3 0.3 1.0 1 0 0 1 1 1 1 Anabaena sensory rhodopsin transducer Sugar_tr PF00083.24 AAAP01000167.1_2 - 2.2e-37 129.0 13.0 3.1e-37 128.5 13.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAAP01000167.1_2 - 3.1e-21 75.7 26.5 3.8e-21 75.4 26.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01000167.1_2 - 0.00027 19.9 4.4 0.00065 18.7 4.4 1.6 1 1 0 1 1 1 1 MFS_1 like family TRI12 PF06609.13 AAAP01000167.1_2 - 0.0062 15.0 7.8 0.0085 14.6 7.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 AAAP01000167.1_2 - 0.037 12.4 15.4 0.075 11.4 15.4 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector Claudin_2 PF13903.6 AAAP01000167.1_2 - 5.3 6.7 9.3 0.81 9.4 3.6 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Thioredoxin_5 PF13743.6 AAAP01000168.1_1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Thioredoxin SNase PF00565.17 AAAP01000169.1_1 - 0.032 14.7 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal nuclease homologue ROK PF00480.20 AAAP01000170.1_1 - 1.8e-18 67.0 1.0 7.8e-12 45.3 0.1 2.8 1 1 1 2 2 2 2 ROK family Cad PF03596.13 AAAP01000171.1_1 - 1.3e-16 61.1 1.3 1.5e-16 60.8 1.3 1.1 1 0 0 1 1 1 1 Cadmium resistance transporter PASTA PF03793.19 AAAP01000171.1_1 - 0.1 12.5 0.0 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 PASTA domain MerC PF03203.14 AAAP01000171.1_1 - 0.88 10.0 6.8 7.1 7.1 6.9 2.2 1 1 0 1 1 1 0 MerC mercury resistance protein HTH_5 PF01022.20 AAAP01000171.1_2 - 2.3e-13 49.7 0.1 3.8e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01000171.1_2 - 5.3e-08 32.8 0.7 5.3e-08 32.8 0.7 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01000171.1_2 - 3.7e-05 23.5 0.6 6.3e-05 22.8 0.6 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAAP01000171.1_2 - 0.00027 20.7 0.2 0.00027 20.7 0.2 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain TrmB PF01978.19 AAAP01000171.1_2 - 0.00072 19.4 0.0 0.00099 19.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 AAAP01000171.1_2 - 0.0016 18.6 0.1 0.0032 17.6 0.1 1.5 1 1 0 1 1 1 1 PaaX-like protein HTH_28 PF13518.6 AAAP01000171.1_2 - 0.0078 16.3 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain RP-C PF03428.13 AAAP01000171.1_2 - 0.013 15.1 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain CENP-B_N PF04218.13 AAAP01000171.1_2 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_27 PF13463.6 AAAP01000171.1_2 - 0.03 14.8 0.1 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.6 AAAP01000171.1_2 - 0.057 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HxlR PF01638.17 AAAP01000171.1_2 - 0.17 11.7 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Penicillinase_R PF03965.16 AAAP01000171.1_2 - 0.21 12.0 0.0 0.25 11.7 0.0 1.1 1 0 0 1 1 1 0 Penicillinase repressor HTH_5 PF01022.20 AAAP01000171.1_3 - 9.6e-11 41.4 0.0 1e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01000171.1_3 - 3.6e-09 36.6 0.2 3.7e-09 36.5 0.2 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01000171.1_3 - 7.2e-06 25.8 0.1 7.4e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAAP01000171.1_3 - 0.0019 17.7 0.1 0.0046 16.5 0.1 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAAP01000171.1_3 - 0.0041 17.1 0.0 0.0043 17.0 0.0 1.3 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain DprA_WH PF17782.1 AAAP01000171.1_3 - 0.011 15.9 0.1 0.012 15.7 0.1 1.0 1 0 0 1 1 1 0 DprA winged helix domain KORA PF16509.5 AAAP01000171.1_3 - 0.012 15.8 0.0 0.013 15.7 0.0 1.0 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_AsnC-type PF13404.6 AAAP01000171.1_3 - 0.022 14.6 0.3 0.039 13.8 0.3 1.6 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_10 PF04967.12 AAAP01000171.1_3 - 0.025 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain HTH_11 PF08279.12 AAAP01000171.1_3 - 0.029 14.3 0.0 0.034 14.1 0.0 1.3 1 1 0 1 1 1 0 HTH domain MarR PF01047.22 AAAP01000171.1_3 - 0.039 13.9 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 MarR family Crp PF00325.20 AAAP01000171.1_3 - 0.092 12.4 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family YdaS_antitoxin PF15943.5 AAAP01000171.1_3 - 0.095 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT KorB PF08535.10 AAAP01000171.1_3 - 0.14 12.2 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 KorB domain GerE PF00196.19 AAAP01000171.1_3 - 0.14 11.7 0.0 0.16 11.5 0.0 1.3 1 1 0 1 1 1 0 Bacterial regulatory proteins, luxR family Glyco_trans_1_4 PF13692.6 AAAP01000172.1_1 - 0.012 16.0 0.1 0.032 14.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 SPW PF03779.14 AAAP01000174.1_1 - 7.7e-16 57.4 31.0 9.3e-11 41.1 6.6 2.3 2 0 0 2 2 2 2 SPW repeat PRD1_DD PF11087.8 AAAP01000174.1_2 - 0.072 12.8 1.1 0.1 12.3 1.1 1.2 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery Asp4 PF16996.5 AAAP01000174.1_2 - 0.42 10.4 2.3 0.71 9.7 2.3 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 ACR_tran PF00873.19 AAAP01000175.1_1 - 9.3e-75 252.0 14.8 1e-74 251.9 14.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ACR_tran PF00873.19 AAAP01000175.1_2 - 0.014 13.1 0.0 0.016 12.9 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Sel_put PF04328.13 AAAP01000176.1_3 - 6.6e-16 58.1 1.2 7.1e-16 58.0 1.2 1.0 1 0 0 1 1 1 1 Selenoprotein, putative PsbX PF06596.11 AAAP01000177.1_1 - 0.12 12.4 1.2 0.27 11.3 1.2 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) FlaF PF07309.11 AAAP01000177.1_2 - 4.6e-06 26.6 0.0 4.8e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FlaF 3HCDH_RFF PF18321.1 AAAP01000177.1_2 - 0.086 13.3 0.9 0.11 12.9 0.9 1.1 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Peptidase_S9 PF00326.21 AAAP01000178.1_2 - 3.3e-63 213.0 0.0 3.7e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 AAAP01000178.1_2 - 5.4e-05 22.0 0.0 9.4e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 AAAP01000178.1_2 - 0.0014 18.5 0.2 0.0024 17.8 0.2 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 AAAP01000178.1_2 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase PHP PF02811.19 AAAP01000179.1_1 - 4.1e-10 40.2 0.0 4.8e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 PHP domain GYR PF02756.14 AAAP01000180.1_2 - 0.069 12.9 0.8 0.096 12.4 0.8 1.2 1 0 0 1 1 1 0 GYR motif GFO_IDH_MocA PF01408.22 AAAP01000181.1_1 - 1.8e-15 57.8 0.3 3e-15 57.1 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 AAAP01000181.1_1 - 0.00028 21.5 2.3 0.0018 18.9 2.6 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DEDD_Tnp_IS110 PF01548.17 AAAP01000181.1_1 - 0.11 12.4 0.1 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 Transposase NAD_binding_9 PF13454.6 AAAP01000183.1_1 - 4.5e-11 43.0 0.0 7.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding MIP PF00230.20 AAAP01000184.1_1 - 4.3e-46 157.5 18.1 5.1e-46 157.2 18.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2384 PF09722.10 AAAP01000185.1_1 - 1.7e-05 24.8 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Multi_ubiq PF14452.6 AAAP01000185.1_2 - 2e-13 50.4 0.1 3e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Multiubiquitin ABC_membrane PF00664.23 AAAP01000186.1_1 - 0.06 13.0 1.2 0.083 12.5 1.2 1.3 1 1 0 1 1 1 0 ABC transporter transmembrane region Fil_haemagg PF05594.14 AAAP01000187.1_1 - 5.7 7.6 14.1 1.3 9.6 2.2 3.4 2 1 0 2 2 2 0 Haemagluttinin repeat PGAP1 PF07819.13 AAAP01000188.1_2 - 3.8e-05 23.5 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 AAAP01000188.1_2 - 0.014 14.6 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glycos_transf_N PF04413.16 AAAP01000188.1_2 - 0.04 13.6 0.2 0.093 12.4 0.1 1.5 1 1 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) LCAT PF02450.15 AAAP01000188.1_2 - 0.33 10.1 0.0 0.4 9.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Urease_alpha PF00449.20 AAAP01000189.1_1 - 7e-55 184.5 0.7 8.3e-55 184.3 0.7 1.1 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AAAP01000189.1_1 - 0.0037 16.8 0.1 0.0079 15.7 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Urease_beta PF00699.20 AAAP01000189.1_2 - 7.9e-23 80.3 0.0 8.7e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit Beta_helix PF13229.6 AAAP01000191.1_1 - 2.7e-05 24.1 0.0 3.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 AAAP01000191.1_1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) VanZ PF04892.12 AAAP01000192.1_1 - 1.4e-18 67.8 0.9 2.2e-18 67.1 0.5 1.5 1 1 0 1 1 1 1 VanZ like family DUF2809 PF10990.8 AAAP01000192.1_1 - 0.0044 17.6 1.4 0.0044 17.6 1.4 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2809) LMWPc PF01451.21 AAAP01000192.1_2 - 2.6e-33 115.4 0.0 3.6e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Kdo_hydroxy PF11004.8 AAAP01000193.1_1 - 6e-09 35.6 0.0 6.9e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase SasG_E PF17041.5 AAAP01000193.1_1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 E domain Sigma70_r4_2 PF08281.12 AAAP01000193.1_2 - 0.005 16.5 0.6 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AAAP01000193.1_2 - 0.043 13.2 0.3 0.11 12.0 0.2 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 IMS_C PF11799.8 AAAP01000193.1_2 - 0.048 14.4 0.7 0.054 14.2 0.7 1.1 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain HpcH_HpaI PF03328.14 AAAP01000194.1_1 - 2.8e-08 33.2 0.0 4.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01000194.1_1 - 8.3e-06 25.2 0.0 9.1e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold ATP-grasp PF02222.22 AAAP01000195.1_1 - 4.5e-05 23.1 0.0 5.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAAP01000195.1_1 - 0.0019 17.7 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF3182 PF11379.8 AAAP01000195.1_1 - 0.0097 14.9 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) Aminotran_1_2 PF00155.21 AAAP01000196.1_1 - 1.1e-21 77.4 0.0 1.2e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RNase_E_G PF10150.9 AAAP01000197.1_1 - 2.6e-17 63.1 0.0 3.7e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family YL1 PF05764.13 AAAP01000197.1_1 - 0.00032 20.9 14.4 0.00037 20.7 14.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 AAAP01000197.1_1 - 0.00043 18.7 13.7 0.00058 18.3 13.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 AAAP01000197.1_1 - 0.00064 18.1 18.6 0.00073 17.9 18.6 1.1 1 0 0 1 1 1 1 Nop14-like family Zip PF02535.22 AAAP01000197.1_1 - 0.0026 17.0 2.0 0.0028 16.9 2.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SDA1 PF05285.12 AAAP01000197.1_1 - 0.003 17.1 19.5 0.0036 16.8 19.5 1.2 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 AAAP01000197.1_1 - 0.0065 15.0 17.9 0.0079 14.7 17.9 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 AAAP01000197.1_1 - 0.015 14.7 19.1 0.017 14.5 19.1 1.1 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 AAAP01000197.1_1 - 0.021 14.7 6.6 0.025 14.4 6.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Vfa1 PF08432.10 AAAP01000197.1_1 - 0.033 14.5 7.1 0.042 14.2 7.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.8 AAAP01000197.1_1 - 0.14 10.9 8.0 0.18 10.6 8.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop53 PF07767.11 AAAP01000197.1_1 - 0.16 11.4 16.9 0.2 11.0 16.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SpoIIP PF07454.11 AAAP01000197.1_1 - 0.16 11.4 6.2 0.19 11.2 6.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SURF2 PF05477.11 AAAP01000197.1_1 - 0.45 10.2 8.9 0.59 9.8 8.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 AAAP01000197.1_1 - 0.48 8.5 36.4 0.62 8.1 36.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 AAAP01000197.1_1 - 0.63 8.8 7.4 0.72 8.6 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 AAAP01000197.1_1 - 0.65 8.7 6.1 0.76 8.5 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.6 AAAP01000197.1_1 - 0.69 8.6 5.6 0.83 8.3 5.6 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 AAAP01000197.1_1 - 1.3 7.7 6.7 1.4 7.6 6.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 AAAP01000197.1_1 - 1.3 7.5 4.0 1.5 7.3 4.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator RR_TM4-6 PF06459.12 AAAP01000197.1_1 - 1.3 8.7 11.6 2.1 8.1 11.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 AAAP01000197.1_1 - 1.6 8.0 16.3 2.8 7.2 16.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Drc1-Sld2 PF11719.8 AAAP01000197.1_1 - 1.7 8.1 15.2 2.2 7.8 15.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein XRCC4 PF06632.12 AAAP01000197.1_1 - 1.8 7.4 12.2 2.3 7.0 12.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Sporozoite_P67 PF05642.11 AAAP01000197.1_1 - 2.3 6.2 16.4 3.5 5.6 16.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.7 AAAP01000197.1_1 - 2.5 6.1 5.4 2.7 6.0 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XAP5 PF04921.14 AAAP01000197.1_1 - 2.6 7.8 11.5 3.6 7.4 11.5 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF4746 PF15928.5 AAAP01000197.1_1 - 3.6 6.9 15.6 4.8 6.5 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) eIF-3c_N PF05470.12 AAAP01000197.1_1 - 3.6 5.8 10.6 4.6 5.4 10.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PTPRCAP PF15713.5 AAAP01000197.1_1 - 4.2 7.7 22.5 7.8 6.8 22.5 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 AAAP01000197.1_1 - 4.5 7.4 9.1 6.8 6.8 9.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FRQ PF09421.10 AAAP01000197.1_1 - 5.7 4.8 12.9 7.1 4.5 12.9 1.0 1 0 0 1 1 1 0 Frequency clock protein CobT PF06213.12 AAAP01000197.1_1 - 5.8 6.2 29.2 9.3 5.6 29.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Connexin PF00029.19 AAAP01000197.1_1 - 5.9 6.6 4.4 7.4 6.3 4.4 1.2 1 0 0 1 1 1 0 Connexin Inhibitor_I71 PF12628.7 AAAP01000197.1_1 - 6.6 6.5 6.1 6.5 6.6 2.1 2.4 2 1 1 3 3 3 0 Falstatin, cysteine peptidase inhibitor MRNIP PF15749.5 AAAP01000197.1_1 - 7.7 7.3 6.8 14 6.5 6.8 1.4 1 0 0 1 1 1 0 MRN-interacting protein RNA_pol_Rpc4 PF05132.14 AAAP01000197.1_1 - 8 6.9 10.1 14 6.1 10.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4820 PF16091.5 AAAP01000197.1_1 - 8.9 5.6 12.3 13 5.0 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_Ag35 PF03286.14 AAAP01000197.1_1 - 9.7 5.9 18.1 19 5.0 18.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PEPcase PF00311.17 AAAP01000198.1_1 - 1.1e-18 66.8 0.0 1.3e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase SBP_bac_11 PF13531.6 AAAP01000199.1_1 - 4e-54 183.8 2.0 5e-54 183.5 2.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAAP01000199.1_1 - 1.5e-05 24.2 0.0 2.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 AAAP01000199.1_1 - 8.4e-05 22.7 0.0 0.0045 17.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAAP01000199.1_1 - 0.0082 15.6 0.0 0.02 14.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DrsE PF02635.15 AAAP01000199.1_2 - 0.00011 22.6 0.0 0.00011 22.5 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DUF4096 PF13340.6 AAAP01000200.1_1 - 3.6e-22 78.4 3.4 5.4e-22 77.8 3.4 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DUF3040 PF11239.8 AAAP01000201.1_1 - 0.00065 19.9 5.2 0.00089 19.5 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) DUF4175 PF13779.6 AAAP01000201.1_1 - 0.096 10.6 1.7 0.1 10.5 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UbiA PF01040.18 AAAP01000201.1_1 - 0.12 11.7 4.6 0.21 10.8 4.6 1.4 1 1 0 1 1 1 0 UbiA prenyltransferase family AAA_3 PF07726.11 AAAP01000201.1_2 - 9.9e-34 116.0 0.0 1.8e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAAP01000201.1_2 - 1.1e-21 76.4 2.9 1.9e-21 75.7 2.9 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAAP01000201.1_2 - 4.9e-06 26.6 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAAP01000201.1_2 - 0.009 15.1 0.0 0.025 13.7 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 AAAP01000201.1_2 - 0.03 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NAPRTase_N PF17767.1 AAAP01000202.1_1 - 8.5e-05 22.9 0.0 0.0001 22.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain PT PF04886.12 AAAP01000202.1_1 - 0.0055 16.2 7.7 0.0089 15.6 7.7 1.3 1 0 0 1 1 1 1 PT repeat UvrA_DNA-bind PF17755.1 AAAP01000205.1_1 - 0.0048 17.2 0.0 0.0095 16.3 0.0 1.5 1 0 0 1 1 1 1 UvrA DNA-binding domain DUF2752 PF10825.8 AAAP01000205.1_1 - 0.074 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Peptidase_M24 PF00557.24 AAAP01000206.1_1 - 4.4e-41 140.9 0.5 5e-41 140.7 0.5 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Pheromone PF08015.11 AAAP01000206.1_2 - 0.1 13.6 0.1 0.1 13.6 0.1 1.1 1 0 0 1 1 1 0 Fungal mating-type pheromone Ald_Xan_dh_C PF01315.22 AAAP01000208.1_1 - 0.097 13.0 0.0 0.097 13.0 0.0 1.1 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_4 PF01565.23 AAAP01000210.1_1 - 1.4e-37 128.5 2.4 1.8e-37 128.2 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain HisKA PF00512.25 AAAP01000211.1_1 - 1.8e-08 34.3 1.6 1.9e-08 34.2 0.2 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HPTransfase PF10090.9 AAAP01000211.1_1 - 0.00096 19.0 0.1 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain Nup54 PF13874.6 AAAP01000211.1_1 - 0.17 12.0 4.0 0.61 10.2 0.2 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 oligo_HPY PF08352.12 AAAP01000212.1_1 - 1.1e-07 32.3 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region DUF4148 PF13663.6 AAAP01000212.1_1 - 0.14 12.4 1.1 0.18 12.0 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) RNB PF00773.19 AAAP01000212.1_2 - 2.7e-28 99.2 0.0 3.2e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 RNB domain MinC_C PF03775.16 AAAP01000214.1_1 - 6e-23 80.8 0.8 6.6e-23 80.6 0.8 1.0 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 AAAP01000214.1_1 - 0.1 11.2 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Bac_luciferase PF00296.20 AAAP01000215.1_2 - 1.7e-05 24.4 0.7 1.8e-05 24.4 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Redoxin PF08534.10 AAAP01000216.1_1 - 3.7e-08 33.2 0.0 4e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01000216.1_1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.0 1 0 0 1 1 1 0 AhpC/TSA family DUF179 PF02622.15 AAAP01000216.1_2 - 1.2e-25 90.3 0.0 1.4e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 HTH_3 PF01381.22 AAAP01000217.1_1 - 4.5e-12 45.8 0.0 6.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix Cupin_2 PF07883.11 AAAP01000217.1_1 - 1.8e-11 43.6 0.3 3.1e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 AAAP01000217.1_1 - 2.1e-11 44.0 3.0 4.4e-11 43.0 3.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01000217.1_1 - 1.8e-07 31.5 0.0 3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 AAAP01000217.1_1 - 6.2e-06 26.1 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 AAAP01000217.1_1 - 0.00013 21.9 0.2 0.00023 21.1 0.2 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_25 PF13413.6 AAAP01000217.1_1 - 0.00035 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01000217.1_1 - 0.0013 18.4 0.7 0.0032 17.2 0.5 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_37 PF13744.6 AAAP01000217.1_1 - 0.0032 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01000217.1_1 - 0.014 15.2 0.2 0.045 13.5 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01000217.1_1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Ribosomal_L9_C PF03948.14 AAAP01000218.1_2 - 3.9e-28 97.7 0.6 4.7e-28 97.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Alk_phosphatase PF00245.20 AAAP01000218.1_2 - 0.034 13.1 0.8 0.035 13.1 0.8 1.1 1 0 0 1 1 1 0 Alkaline phosphatase PGK PF00162.19 AAAP01000219.1_1 - 2e-24 86.2 0.0 2.3e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3280 PF11684.8 AAAP01000220.1_1 - 6.8e-12 46.0 0.0 7.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) ACPS PF01648.20 AAAP01000221.1_2 - 4.6e-13 49.3 0.0 5.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 5_nucleotid_C PF02872.18 AAAP01000222.1_1 - 2.6e-17 63.5 0.0 3.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain DUF756 PF05506.12 AAAP01000222.1_1 - 1.4 9.9 4.5 0.91 10.5 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF756) Pribosyl_synth PF14572.6 AAAP01000223.1_1 - 1.5e-16 60.9 0.1 1.7e-16 60.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AAAP01000223.1_1 - 4.2e-07 29.6 0.1 5e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GreA_GreB PF01272.19 AAAP01000223.1_2 - 2.1e-20 72.4 0.0 2.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term tRNA-synt_1 PF00133.22 AAAP01000225.1_1 - 1e-19 70.3 0.0 4e-13 48.5 0.0 2.8 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 AAAP01000225.1_1 - 2.7e-16 59.6 0.0 4.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.13 AAAP01000225.1_1 - 2.2e-08 34.2 0.0 3.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AAAP01000225.1_1 - 8.8e-05 21.4 0.0 0.0025 16.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AAAP01000225.1_1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zf-ISL3 PF14690.6 AAAP01000225.1_1 - 0.13 12.9 1.4 15 6.4 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 AAAP01000225.1_1 - 0.2 11.8 2.6 2.1 8.5 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 AAAP01000225.1_1 - 0.26 10.8 4.3 6.2 6.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AAAP01000225.1_1 - 4.5 7.3 5.5 37 4.4 0.6 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Aminotran_1_2 PF00155.21 AAAP01000226.1_1 - 7.8e-12 45.0 0.0 9.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Orn_DAP_Arg_deC PF00278.22 AAAP01000227.1_1 - 3.8e-28 97.6 0.0 4.5e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 AAAP01000227.1_1 - 3.9e-26 91.9 0.0 4.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ala_racemase_N PF01168.20 AAAP01000227.1_1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Glyco_transf_21 PF13506.6 AAAP01000228.1_1 - 0.00012 21.6 0.1 0.00031 20.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AAAP01000228.1_1 - 0.00023 21.1 0.1 0.00031 20.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 AAAP01000228.1_1 - 0.00087 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 AAAP01000228.1_1 - 0.0033 17.3 1.1 0.015 15.2 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01000228.1_1 - 0.025 14.0 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MerC PF03203.14 AAAP01000228.1_1 - 0.054 14.0 0.3 0.081 13.4 0.3 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3040 PF11239.8 AAAP01000228.1_1 - 0.85 9.9 6.7 0.77 10.1 2.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF5353 PF17304.2 AAAP01000228.1_1 - 2.6 7.9 7.2 0.91 9.3 1.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5353) HWE_HK PF07536.14 AAAP01000229.1_1 - 6.3e-26 90.9 0.7 1.8e-25 89.4 0.7 1.8 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 AAAP01000229.1_1 - 8.2e-16 58.1 0.0 6.6e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01000229.1_1 - 1.6e-11 44.4 1.7 9e-09 35.6 0.3 2.8 3 1 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01000229.1_1 - 6.7e-07 29.5 0.0 0.0019 18.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain HisKA_2 PF07568.12 AAAP01000229.1_1 - 4.4e-06 26.7 0.5 1.1e-05 25.4 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase HATPase_c_2 PF13581.6 AAAP01000229.1_1 - 0.0033 17.4 0.2 0.0086 16.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Cluap1 PF10234.9 AAAP01000229.1_1 - 0.012 15.0 4.6 0.067 12.6 0.4 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 PAS PF00989.25 AAAP01000229.1_1 - 0.022 14.8 0.0 6.8 6.7 0.0 2.5 2 0 0 2 2 2 0 PAS fold DUF4140 PF13600.6 AAAP01000229.1_1 - 0.043 14.3 1.8 3.9 8.0 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4201 PF13870.6 AAAP01000229.1_1 - 0.86 9.3 4.6 1.7 8.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Aldolase PF01081.19 AAAP01000230.1_1 - 4e-44 150.4 5.2 4.7e-44 150.2 5.2 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase IMPDH PF00478.25 AAAP01000230.1_1 - 0.028 13.4 1.8 0.07 12.1 1.3 1.8 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain HTH_IclR PF09339.10 AAAP01000230.1_2 - 6.7e-12 45.0 1.3 6.7e-12 45.0 1.3 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAAP01000230.1_2 - 1.8e-05 24.6 0.5 3.7e-05 23.5 0.5 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAAP01000230.1_2 - 0.00067 19.7 1.4 0.017 15.1 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 AAAP01000230.1_2 - 0.04 14.3 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TetR_N PF00440.23 AAAP01000230.1_2 - 0.045 13.6 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Crp_2 PF13545.6 AAAP01000230.1_2 - 0.085 12.8 0.0 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain B-block_TFIIIC PF04182.12 AAAP01000230.1_2 - 0.12 12.5 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MIB_HERC2 PF06701.13 AAAP01000231.1_1 - 0.064 13.5 0.1 0.075 13.3 0.1 1.0 1 0 0 1 1 1 0 Mib_herc2 Malate_DH PF12434.8 AAAP01000232.1_1 - 0.023 14.7 0.6 0.026 14.5 0.6 1.1 1 0 0 1 1 1 0 Malate dehydrogenase enzyme PLDc_N PF13396.6 AAAP01000233.1_1 - 9.3e-05 22.3 5.2 0.00014 21.7 5.2 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal OAR PF03826.17 AAAP01000233.1_2 - 0.069 13.0 2.7 0.12 12.2 2.7 1.4 1 0 0 1 1 1 0 OAR domain Arginosuc_synth PF00764.19 AAAP01000234.1_1 - 1.4e-77 261.7 0.0 1.5e-77 261.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase PAS_3 PF08447.12 AAAP01000238.1_1 - 5.8e-09 36.1 0.0 3.3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 AAAP01000238.1_1 - 8.1e-07 29.7 0.3 4.4e-06 27.4 0.0 2.0 2 1 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AAAP01000238.1_1 - 2.6e-06 27.8 1.5 3.2e-05 24.3 0.1 2.3 2 1 0 2 2 2 1 GAF domain PAS_8 PF13188.7 AAAP01000238.1_1 - 5.1e-06 26.4 0.2 1.1e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAAP01000238.1_1 - 2.9e-05 24.3 1.3 0.00016 21.9 0.0 2.1 1 1 1 2 2 2 1 PAS fold PAS PF00989.25 AAAP01000238.1_1 - 0.0042 17.1 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01000238.1_1 - 0.0065 16.7 0.0 0.015 15.6 0.0 1.6 2 0 0 2 2 2 1 PAS domain FMN_bind PF04205.14 AAAP01000240.1_1 - 5.3e-06 26.9 0.0 8.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 FMN-binding domain TTc_toxin_rep PF18807.1 AAAP01000240.1_1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Tripartite Tc toxins repeat ATG16 PF08614.11 AAAP01000241.1_1 - 0.00058 20.2 8.9 0.00099 19.4 8.7 1.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 AAAP01000241.1_1 - 0.0013 18.1 3.7 0.0017 17.7 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 AAAP01000241.1_1 - 0.0065 16.3 0.7 0.011 15.6 0.7 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 UPF0242 PF06785.11 AAAP01000241.1_1 - 0.011 15.8 0.5 0.015 15.4 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 AAAP01000241.1_1 - 0.049 13.7 1.6 0.08 13.0 1.6 1.3 1 0 0 1 1 1 0 Laminin Domain II APG6_N PF17675.1 AAAP01000241.1_1 - 0.075 13.6 6.7 0.12 12.8 6.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF16 PF01519.16 AAAP01000241.1_1 - 0.21 12.1 0.3 0.62 10.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.6 AAAP01000241.1_1 - 0.32 10.5 4.1 0.43 10.1 4.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 AAAP01000241.1_1 - 0.37 11.1 7.1 0.46 10.8 4.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain HemX PF04375.14 AAAP01000241.1_1 - 0.37 10.0 8.3 0.71 9.1 8.3 1.5 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4164 PF13747.6 AAAP01000241.1_1 - 0.46 10.8 14.6 3 8.2 13.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) FliT PF05400.13 AAAP01000241.1_1 - 0.94 10.3 16.2 0.16 12.8 9.5 2.5 1 1 1 2 2 2 0 Flagellar protein FliT DUF3584 PF12128.8 AAAP01000241.1_1 - 1.1 6.7 7.5 1.3 6.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.12 AAAP01000241.1_1 - 1.9 9.2 8.3 0.33 11.6 1.6 2.6 1 1 1 2 2 2 0 SlyX SPOUT_MTase PF02590.17 AAAP01000241.1_2 - 1.1e-09 38.5 0.1 1.2e-09 38.3 0.1 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase MISS PF15822.5 AAAP01000241.1_2 - 0.0094 15.8 1.1 0.0094 15.8 1.1 1.0 1 0 0 1 1 1 1 MAPK-interacting and spindle-stabilising protein-like Aconitase PF00330.20 AAAP01000242.1_1 - 1e-56 192.9 0.0 1.2e-56 192.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Acyl_transf_2 PF02273.15 AAAP01000242.1_1 - 0.062 12.5 0.0 0.22 10.7 0.0 1.7 1 1 1 2 2 2 0 Acyl transferase Extensin-like_C PF06904.12 AAAP01000243.1_1 - 8.2e-17 61.8 0.0 8.3e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Extensin-like protein C-terminus PG_binding_1 PF01471.18 AAAP01000243.1_2 - 0.00015 21.9 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain TMEM247 PF15444.6 AAAP01000243.1_2 - 0.076 13.1 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DUF2147 PF09917.9 AAAP01000244.1_1 - 9e-29 100.4 0.1 1.4e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2147) CinA PF02464.17 AAAP01000245.1_2 - 6.3e-47 159.0 3.5 7.7e-47 158.7 3.5 1.0 1 0 0 1 1 1 1 Competence-damaged protein UPF0254 PF06787.11 AAAP01000245.1_2 - 0.0049 16.7 0.0 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0254) RTC_insert PF05189.13 AAAP01000245.1_2 - 0.013 16.0 0.3 0.038 14.5 0.1 1.9 1 1 1 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4051 PF13260.6 AAAP01000245.1_3 - 0.21 11.3 1.5 0.27 11.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) SBP_bac_8 PF13416.6 AAAP01000246.1_1 - 5.6e-05 23.1 0.0 7.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SpoIID PF08486.10 AAAP01000247.1_1 - 5.4e-24 84.6 0.1 8e-24 84.0 0.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein DegT_DnrJ_EryC1 PF01041.17 AAAP01000247.1_2 - 3.7e-07 29.8 0.0 4.3e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_S24 PF00717.23 AAAP01000248.1_1 - 6.2e-16 58.1 0.0 1.1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like LexA_DNA_bind PF01726.16 AAAP01000248.1_1 - 0.0037 17.0 0.4 0.015 15.1 0.1 2.0 2 0 0 2 2 2 1 LexA DNA binding domain TonB_dep_Rec PF00593.24 AAAP01000250.1_1 - 7.6e-32 111.8 7.7 9e-32 111.6 7.7 1.0 1 0 0 1 1 1 1 TonB dependent receptor dTDP_sugar_isom PF00908.17 AAAP01000251.1_1 - 4.5e-59 198.9 0.0 5e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase E3_binding PF02817.17 AAAP01000251.1_1 - 0.087 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain RmlD_sub_bind PF04321.17 AAAP01000251.1_2 - 0.0073 15.4 0.1 0.0076 15.4 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAAP01000251.1_2 - 0.012 15.1 0.1 0.012 15.1 0.1 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAAP01000251.1_2 - 0.015 14.8 0.2 0.015 14.8 0.2 1.0 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 AAAP01000251.1_2 - 0.2 10.6 0.0 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ABC_tran PF00005.27 AAAP01000252.1_1 - 0.017 15.7 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter HCV_env PF01539.17 AAAP01000252.1_2 - 0.058 13.1 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 RskA PF10099.9 AAAP01000252.1_2 - 0.12 12.6 7.5 0.19 12.0 7.5 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Syndecan PF01034.20 AAAP01000252.1_2 - 2.3 8.2 3.6 6.1 6.8 2.7 1.9 2 0 0 2 2 2 0 Syndecan domain Aminotran_1_2 PF00155.21 AAAP01000254.1_1 - 5.3e-09 35.7 0.0 6.3e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Exo_endo_phos PF03372.23 AAAP01000254.1_2 - 1e-07 31.7 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Amidohydro_3 PF07969.11 AAAP01000255.1_1 - 1.4e-24 87.4 3.7 1.6e-24 87.2 3.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AAAP01000255.1_1 - 5.4e-07 29.2 0.0 6.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family KH_4 PF13083.6 AAAP01000256.1_1 - 1.4e-19 69.7 0.1 1.5e-19 69.6 0.1 1.0 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 AAAP01000256.1_1 - 3.9e-05 23.4 0.0 4.4e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 KH domain KH_1 PF00013.29 AAAP01000256.1_1 - 0.0038 17.0 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 KH domain RimM PF01782.18 AAAP01000256.1_2 - 2.7e-10 40.3 0.1 7.7e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 RimM N-terminal domain FtsK_SpoIIIE PF01580.18 AAAP01000257.1_1 - 4.8e-56 189.8 0.5 3.1e-41 141.4 0.0 2.0 1 1 1 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.7 AAAP01000257.1_1 - 6.7e-05 22.0 0.0 9.4e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 AAAP01000257.1_1 - 7.6e-05 22.9 0.1 0.00014 22.0 0.1 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AAAP01000257.1_1 - 0.00076 18.5 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 AAAP01000257.1_1 - 0.0015 17.8 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) T2SSE PF00437.20 AAAP01000257.1_1 - 0.0028 16.8 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TniB PF05621.11 AAAP01000257.1_1 - 0.0029 17.0 0.1 0.25 10.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein Adeno_IVa2 PF02456.15 AAAP01000257.1_1 - 0.003 16.4 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 AAAP01000257.1_1 - 0.0039 17.2 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01000257.1_1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 AAAP01000257.1_1 - 0.01 14.9 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 AAAP01000257.1_1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 AAAP01000257.1_1 - 0.012 15.2 3.1 0.82 9.2 3.1 2.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AAAP01000257.1_1 - 0.012 15.6 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_19 PF13245.6 AAAP01000257.1_1 - 0.013 15.8 0.1 0.051 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 AAAP01000257.1_1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 AAAP01000257.1_1 - 0.015 15.7 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01000257.1_1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 AAAP01000257.1_1 - 0.031 13.6 0.0 0.083 12.2 0.0 1.7 2 0 0 2 2 2 0 AIG1 family Zeta_toxin PF06414.12 AAAP01000257.1_1 - 0.042 13.1 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 AAAP01000257.1_1 - 0.047 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 AAAP01000257.1_1 - 0.067 12.2 0.4 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 AAAP01000257.1_1 - 0.069 12.9 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 AAAP01000257.1_1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 AAAP01000257.1_1 - 0.12 12.2 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 AAAP01000257.1_1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 AAAP01000257.1_1 - 0.21 11.6 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CSD PF00313.22 AAAP01000259.1_1 - 8e-33 112.1 0.0 8.6e-33 112.0 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01000259.1_1 - 0.0028 17.3 0.1 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain MMPL PF03176.15 AAAP01000260.1_1 - 1.8e-34 119.1 12.3 2.6e-34 118.7 12.3 1.2 1 0 0 1 1 1 1 MMPL family AFG1_ATPase PF03969.16 AAAP01000261.1_1 - 5.4e-40 137.4 0.0 6.4e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase Pur_DNA_glyco PF02245.16 AAAP01000261.1_2 - 1.5e-37 128.8 0.0 1.7e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Peptidase_M22 PF00814.25 AAAP01000262.1_1 - 2e-56 191.7 0.0 2.3e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AAAP01000262.1_1 - 0.041 13.5 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MCPsignal PF00015.21 AAAP01000263.1_1 - 1.6e-18 67.1 3.8 2.6e-18 66.4 3.8 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAAP01000263.1_1 - 3.9e-07 30.1 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cache domain Hexapep PF00132.24 AAAP01000265.1_1 - 0.0056 16.4 4.2 0.11 12.3 0.1 3.6 4 1 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) N6_N4_Mtase PF01555.18 AAAP01000266.1_2 - 1.9e-16 60.5 0.0 2.4e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 AAAP01000266.1_2 - 0.074 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 YafQ_toxin PF15738.5 AAAP01000267.1_2 - 3.2e-31 107.5 0.1 3.8e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 AAAP01000267.1_2 - 2.8e-06 27.9 0.3 3.1e-06 27.7 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF4096 PF13340.6 AAAP01000267.1_3 - 3.3e-16 59.3 0.2 3.8e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DciA PF05258.12 AAAP01000269.1_1 - 2.8e-22 78.9 0.0 3.9e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA HemY_N PF07219.13 AAAP01000270.1_1 - 3.8e-27 94.6 1.0 3.8e-27 94.6 1.0 4.0 2 1 2 4 4 4 1 HemY protein N-terminus TPR_16 PF13432.6 AAAP01000270.1_1 - 0.96 10.1 13.0 0.19 12.4 2.4 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2953 PF11167.8 AAAP01000270.1_1 - 10 6.3 6.1 2.4 8.3 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) HEM4 PF02602.15 AAAP01000271.1_1 - 2.2e-16 59.9 0.3 2.9e-16 59.5 0.3 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PALP PF00291.25 AAAP01000273.1_1 - 3.9e-09 36.4 0.2 4.1e-09 36.3 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3767 PF12597.8 AAAP01000273.1_1 - 0.11 12.3 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) NLPC_P60 PF00877.19 AAAP01000274.1_1 - 3.9e-17 62.2 0.0 4.8e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 NlpC/P60 family CHAP PF05257.16 AAAP01000274.1_1 - 0.0023 18.5 0.0 0.0031 18.0 0.0 1.2 1 0 0 1 1 1 1 CHAP domain Amidase_6 PF12671.7 AAAP01000274.1_1 - 0.016 15.4 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Putative amidase domain NMT1_2 PF13379.6 AAAP01000275.1_1 - 4.5e-35 121.5 0.1 6.6e-35 121.0 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01000275.1_1 - 3.5e-09 36.9 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AAAP01000275.1_1 - 0.0015 18.0 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Glyco_trans_1_2 PF13524.6 AAAP01000276.1_1 - 2.2e-20 72.9 0.1 3.5e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Na_H_Exchanger PF00999.21 AAAP01000277.1_1 - 6.8e-26 90.9 19.2 9e-26 90.5 19.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Rhomboid PF01694.22 AAAP01000277.1_1 - 5.2 7.1 13.9 64 3.5 13.9 2.1 1 1 0 1 1 1 0 Rhomboid family DEAD PF00270.29 AAAP01000279.1_1 - 4.2e-09 36.4 0.1 5.6e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase NUDIX PF00293.28 AAAP01000280.1_1 - 1.4e-08 34.8 0.0 2.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Glyco_trans_2_3 PF13632.6 AAAP01000281.1_1 - 1e-13 51.6 0.9 4.8e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAAP01000281.1_1 - 1.2e-11 44.4 0.0 2.5e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 AAAP01000281.1_1 - 1.2e-08 34.9 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Rtt106 PF08512.12 AAAP01000281.1_1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Histone chaperone Rttp106-like GGDEF PF00990.21 AAAP01000282.1_1 - 5e-23 81.6 0.0 8.2e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAAP01000282.1_1 - 8.4e-07 29.1 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain DUF1320 PF07030.12 AAAP01000283.1_1 - 9.9e-13 48.3 0.2 1.1e-12 48.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1320) DHDPS PF00701.22 AAAP01000284.1_1 - 1.2e-10 40.6 0.0 1.3e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF4096 PF13340.6 AAAP01000284.1_2 - 3.4e-14 52.8 1.8 3.6e-14 52.7 1.8 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DUF1236 PF06823.12 AAAP01000285.1_1 - 1e-08 34.9 1.2 1.1e-08 34.8 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1236) Romo1 PF10247.9 AAAP01000285.1_2 - 0.019 15.3 0.7 0.032 14.6 0.7 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Bacteriocin_IIc PF10439.9 AAAP01000285.1_2 - 0.13 12.4 14.4 0.2 11.8 14.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.13 AAAP01000285.1_2 - 0.41 10.9 5.4 0.5 10.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4148 PF13663.6 AAAP01000285.1_2 - 4.5 7.5 8.0 6.1 7.1 8.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) PepSY_TM PF03929.16 AAAP01000286.1_1 - 3e-06 27.1 0.0 3.2e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY_TM PF03929.16 AAAP01000286.1_2 - 3.4e-09 36.8 0.6 4.1e-09 36.5 0.6 1.0 1 0 0 1 1 1 1 PepSY-associated TM region DUF3652 PF12372.8 AAAP01000287.1_1 - 0.043 13.7 0.5 0.7 9.8 0.1 2.7 3 0 0 3 3 3 0 Huntingtin protein region MarC PF01914.17 AAAP01000288.1_1 - 7.5e-33 113.6 1.9 8.3e-33 113.5 1.9 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein Trp_oprn_chp PF09534.10 AAAP01000288.1_1 - 0.15 11.9 16.6 0.098 12.4 11.6 2.5 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) His_biosynth PF00977.21 AAAP01000289.1_1 - 1.2e-08 34.7 0.3 4.4e-08 32.9 0.3 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein Fae PF08714.11 AAAP01000289.1_2 - 2.6e-26 92.5 0.2 3.1e-26 92.2 0.2 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Phenol_MetA_deg PF13557.6 AAAP01000290.1_1 - 0.0004 20.4 1.7 0.0005 20.1 1.6 1.3 1 1 0 1 1 1 1 Putative MetA-pathway of phenol degradation Thioredoxin_4 PF13462.6 AAAP01000291.1_1 - 1.8e-12 47.8 0.0 1.8e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AAAP01000291.1_1 - 6.1e-06 26.2 0.0 6.5e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 AAAP01000291.1_1 - 0.00015 21.7 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DeoC PF01791.9 AAAP01000291.1_1 - 0.041 13.5 0.0 0.045 13.4 0.0 1.0 1 0 0 1 1 1 0 DeoC/LacD family aldolase ATPase_gene1 PF09527.10 AAAP01000291.1_2 - 6e-16 58.4 6.6 7.4e-16 58.1 6.6 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter FUSC_2 PF13515.6 AAAP01000291.1_2 - 0.0046 17.1 1.7 0.0053 16.9 1.7 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF3040 PF11239.8 AAAP01000291.1_2 - 0.057 13.7 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TraT PF05818.12 AAAP01000291.1_2 - 0.16 11.7 0.1 0.19 11.4 0.1 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein ATP-synt_A PF00119.20 AAAP01000291.1_3 - 6.5e-23 81.8 8.1 7.7e-23 81.5 8.1 1.0 1 0 0 1 1 1 1 ATP synthase A chain ArAE_1 PF06081.11 AAAP01000291.1_3 - 0.91 9.7 11.7 10 6.3 11.7 2.1 1 1 0 1 1 1 0 Aromatic acid exporter family member 1 DUF4389 PF14333.6 AAAP01000291.1_3 - 3.3 7.7 12.5 8.6 6.4 5.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4389) SSF PF00474.17 AAAP01000292.1_1 - 3e-48 164.7 18.8 3.6e-48 164.4 18.8 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Nramp PF01566.18 AAAP01000292.1_1 - 0.00081 18.5 10.2 0.0011 18.0 10.2 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein MipA PF06629.12 AAAP01000293.1_2 - 9.5e-05 22.7 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 MltA-interacting protein MipA MCPsignal PF00015.21 AAAP01000294.1_1 - 3.9e-19 69.1 22.6 8.3e-19 68.0 4.7 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAAP01000294.1_1 - 7.8e-13 48.4 2.3 5e-12 45.7 0.0 2.5 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01000294.1_1 - 4.7e-05 23.7 0.2 4.7e-05 23.7 0.2 3.9 4 1 0 4 4 4 1 HAMP domain FIT1_2 PF17357.2 AAAP01000294.1_1 - 3.3 7.9 8.2 0.35 11.0 2.9 2.0 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 ParA PF10609.9 AAAP01000295.1_1 - 1.6e-71 240.6 0.4 2e-71 240.3 0.4 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AAAP01000295.1_1 - 3.3e-12 46.4 0.3 7.9e-12 45.2 0.1 1.8 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AAAP01000295.1_1 - 3.9e-12 46.3 0.0 7.6e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01000295.1_1 - 1.5e-08 34.8 0.1 6.6e-08 32.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 AAAP01000295.1_1 - 2.1e-07 30.5 0.0 4e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAAP01000295.1_1 - 3.6e-06 26.4 1.0 6.6e-05 22.2 0.8 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 AAAP01000295.1_1 - 6.9e-05 22.5 0.7 0.00018 21.1 0.7 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 AAAP01000295.1_1 - 0.00019 21.0 0.3 0.00064 19.3 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 AAAP01000295.1_1 - 0.0049 16.2 0.1 0.0074 15.6 0.1 1.2 1 0 0 1 1 1 1 VirC1 protein APS_kinase PF01583.20 AAAP01000295.1_1 - 0.05 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MeaB PF03308.16 AAAP01000295.1_1 - 0.05 12.6 0.9 0.074 12.0 0.3 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AAAP01000295.1_1 - 0.072 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 AAAP01000295.1_1 - 0.25 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TPR_12 PF13424.6 AAAP01000297.1_1 - 0.055 13.8 0.4 0.1 12.9 0.4 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat NOA36 PF06524.12 AAAP01000297.1_1 - 1.9 7.7 12.0 2.1 7.6 12.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 AAAP01000297.1_1 - 2.9 6.9 14.7 3.1 6.8 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 AAAP01000297.1_1 - 4.3 5.8 4.9 3.6 6.0 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 AAAP01000297.1_1 - 7.8 4.5 11.8 7.5 4.5 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SPDY PF03771.16 AAAP01000297.1_2 - 0.4 10.7 4.8 0.19 11.7 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF317) ParBc PF02195.18 AAAP01000300.1_1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain Hydantoinase_B PF02538.14 AAAP01000300.1_1 - 0.00051 18.6 0.2 0.00069 18.1 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase VanY PF02557.17 AAAP01000301.1_1 - 8.8e-12 45.0 0.7 5.2e-11 42.5 0.7 2.0 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PASTA PF03793.19 AAAP01000301.1_1 - 2.7e-11 43.1 4.7 5.8e-11 42.1 3.9 2.0 2 0 0 2 2 2 1 PASTA domain Peptidase_M15_4 PF13539.6 AAAP01000301.1_1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SufE PF02657.15 AAAP01000302.1_1 - 3.1e-30 104.5 0.0 3.7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Fe-S metabolism associated domain VKOR PF07884.14 AAAP01000303.1_1 - 1.8e-23 83.1 11.6 1.8e-23 83.1 11.6 1.7 2 0 0 2 2 2 1 Vitamin K epoxide reductase family Strabismus PF06638.11 AAAP01000303.1_1 - 0.11 11.2 2.7 0.13 10.9 2.7 1.1 1 0 0 1 1 1 0 Strabismus protein PPC PF04151.15 AAAP01000303.1_2 - 0.0048 18.0 0.3 0.0067 17.5 0.3 1.2 1 0 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain CBM65_1 PF18259.1 AAAP01000303.1_2 - 0.069 13.3 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding module 65 domain 1 OpuAC PF04069.12 AAAP01000303.1_2 - 0.1 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Prenyltransf PF01255.19 AAAP01000304.1_1 - 1.5e-35 122.7 0.0 1.7e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1707 PF08044.11 AAAP01000304.1_1 - 0.047 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) CTP_transf_1 PF01148.20 AAAP01000304.1_2 - 1.3e-22 80.8 3.2 1.6e-22 80.5 3.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family TetR_N PF00440.23 AAAP01000305.1_2 - 1e-15 57.2 3.2 1.2e-15 57.0 0.6 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAAP01000305.1_2 - 6.9e-07 29.5 0.3 2.2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 AAAP01000305.1_2 - 0.02 14.9 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 AAAP01000306.1_2 - 0.014 16.2 0.1 0.021 15.7 0.1 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ISK_Channel PF02060.15 AAAP01000306.1_2 - 0.16 11.7 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Slow voltage-gated potassium channel B3_4 PF03483.17 AAAP01000309.1_1 - 5.2e-65 218.4 0.0 5.9e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 B3/4 domain SNARE_assoc PF09335.11 AAAP01000310.1_1 - 2.3e-13 50.7 6.1 4e-13 49.9 6.1 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF3084 PF11283.8 AAAP01000310.1_1 - 0.038 14.0 0.2 0.099 12.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) ThrE_2 PF12821.7 AAAP01000311.1_2 - 4e-22 78.7 17.7 4.4e-22 78.6 17.7 1.0 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE ThrE PF06738.12 AAAP01000311.1_2 - 8.1e-08 31.9 20.5 8.8e-08 31.8 20.5 1.0 1 0 0 1 1 1 1 Putative threonine/serine exporter TM_helix PF05552.12 AAAP01000311.1_2 - 0.13 12.3 7.7 2.8 8.0 0.6 2.5 2 0 0 2 2 2 0 Conserved TM helix TMEM100 PF16311.5 AAAP01000311.1_2 - 0.44 10.1 2.1 0.54 9.8 2.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 PEMT PF04191.13 AAAP01000311.1_2 - 8.9 6.8 8.9 0.4 11.1 1.2 2.4 2 1 0 3 3 3 0 Phospholipid methyltransferase GMC_oxred_C PF05199.13 AAAP01000312.1_1 - 1.1e-17 64.8 0.6 1.8e-17 64.2 0.6 1.5 1 1 0 1 1 1 1 GMC oxidoreductase OEP PF02321.18 AAAP01000313.1_1 - 2.6e-20 73.0 15.2 3.3e-20 72.7 15.2 1.1 1 0 0 1 1 1 1 Outer membrane efflux protein DUF3168 PF11367.8 AAAP01000313.1_1 - 1.7 8.8 9.8 0.067 13.4 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3168) DUF3459 PF11941.8 AAAP01000314.1_1 - 8e-15 54.9 0.5 2.2e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Alpha-amylase PF00128.24 AAAP01000314.1_1 - 3.7e-14 53.0 0.0 5e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 AAAP01000314.1_1 - 0.005 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 AAAP01000314.1_1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAAP01000315.1_2 - 0.0092 16.6 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain OmpA PF00691.20 AAAP01000316.1_1 - 0.0015 18.9 0.0 0.0034 17.7 0.0 1.8 1 1 0 1 1 1 1 OmpA family DUF3646 PF12362.8 AAAP01000316.1_1 - 3.9 7.8 8.8 3.4 8.0 0.0 3.4 3 1 0 3 3 3 0 DNA polymerase III gamma and tau subunits C terminal PEGA PF08308.11 AAAP01000317.1_1 - 0.054 13.4 0.1 0.064 13.2 0.1 1.2 1 0 0 1 1 1 0 PEGA domain SIR2_2 PF13289.6 AAAP01000318.1_2 - 0.00036 20.7 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 SIR2-like domain Aldo_ket_red PF00248.21 AAAP01000320.1_1 - 2.8e-53 181.0 0.0 3.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1266 PF06889.11 AAAP01000320.1_1 - 0.051 13.6 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF418 PF04235.12 AAAP01000320.1_2 - 3.3e-07 30.4 7.2 4.6e-07 29.9 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF418) PALP PF00291.25 AAAP01000321.1_1 - 9.5e-24 84.3 1.1 1.7e-23 83.5 1.1 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GGDEF PF00990.21 AAAP01000322.1_1 - 3.2e-35 121.3 0.0 5.2e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain EAL PF00563.20 AAAP01000322.1_1 - 1.9e-18 66.9 0.0 4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 EAL domain Peptidase_M16_C PF05193.21 AAAP01000323.1_1 - 1.6e-31 109.8 0.0 2.2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain BBE PF08031.12 AAAP01000324.1_2 - 3.5e-07 30.2 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like AAA_5 PF07728.14 AAAP01000325.1_1 - 7.6e-21 74.6 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AAAP01000325.1_1 - 0.035 14.0 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA-synt_His PF13393.6 AAAP01000326.1_1 - 1e-25 90.7 0.0 1.3e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase PsbQ PF05757.11 AAAP01000328.1_1 - 0.094 12.4 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) UbiA PF01040.18 AAAP01000329.1_1 - 2e-53 181.3 17.7 2.5e-53 180.9 17.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family SURF4 PF02077.15 AAAP01000329.1_1 - 1.3 8.5 7.2 1.5 8.4 0.6 2.1 2 0 0 2 2 2 0 SURF4 family TamB PF04357.13 AAAP01000330.1_1 - 1.5e-08 34.3 1.1 0.00055 19.3 0.0 2.1 2 0 0 2 2 2 2 TamB, inner membrane protein subunit of TAM complex T2SSN PF01203.19 AAAP01000330.1_1 - 3.1e-05 24.3 3.3 4.4e-05 23.8 3.3 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein N DUF748 PF05359.11 AAAP01000330.1_1 - 0.039 14.1 0.7 2.5 8.2 0.0 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF748) Urease_beta PF00699.20 AAAP01000331.1_1 - 1.2e-42 143.9 0.0 1.6e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 AAAP01000331.1_1 - 1.7e-23 82.8 0.3 1.7e-22 79.6 0.2 2.1 2 0 0 2 2 2 1 Urease, gamma subunit Peptidase_S64 PF08192.11 AAAP01000331.1_1 - 0.19 10.2 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Cytidylate_kin2 PF13189.6 AAAP01000331.1_2 - 0.022 14.9 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family ALIX_LYPXL_bnd PF13949.6 AAAP01000331.1_2 - 0.051 12.9 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Peptidase_S9 PF00326.21 AAAP01000332.1_1 - 2.9e-06 26.9 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AAAP01000332.1_1 - 4.9e-05 24.0 13.1 4.9e-05 24.0 13.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAAP01000332.1_1 - 0.0045 16.6 0.3 0.019 14.6 0.2 1.9 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 AAAP01000332.1_1 - 0.015 14.0 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RP-C_C PF11800.8 AAAP01000332.1_1 - 0.093 12.8 1.6 0.15 12.1 1.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region AICARFT_IMPCHas PF01808.18 AAAP01000333.1_1 - 7.3e-82 275.1 0.0 8.1e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme ABC_tran PF00005.27 AAAP01000335.1_1 - 1.4e-08 35.4 0.0 2.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01000335.1_1 - 2.3e-07 31.0 0.2 3e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01000335.1_1 - 1.9e-06 27.5 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain CbiQ PF02361.16 AAAP01000335.1_2 - 1.9e-05 24.4 0.1 2e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Cobalt transport protein Oxidored_FMN PF00724.20 AAAP01000337.1_2 - 7.1e-08 32.1 0.0 8.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AAAP01000337.1_2 - 0.00071 18.8 0.0 0.00089 18.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 AAAP01000337.1_2 - 0.00097 18.6 0.1 0.0016 17.9 0.1 1.3 1 1 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator Transglut_core PF01841.19 AAAP01000338.1_1 - 2e-14 54.0 0.3 3e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAAP01000338.1_1 - 0.0064 16.0 0.2 0.39 10.2 0.2 2.0 1 1 1 2 2 2 2 Transglutaminase-like domain Peripla_BP_2 PF01497.18 AAAP01000339.1_1 - 3.3e-05 23.6 0.1 4.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein YdjC PF04794.12 AAAP01000341.1_1 - 2.5e-36 125.8 0.4 2.9e-36 125.6 0.4 1.0 1 0 0 1 1 1 1 YdjC-like protein ACP PF06857.11 AAAP01000341.1_1 - 0.053 13.8 0.2 1.5 9.1 0.3 2.3 2 1 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) ACR_tran PF00873.19 AAAP01000342.1_1 - 2.1e-06 25.8 4.7 2.5e-06 25.5 4.7 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Rax2 PF12768.7 AAAP01000342.1_1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Peripla_BP_3 PF13377.6 AAAP01000342.1_2 - 7.9e-31 107.6 0.5 8.7e-31 107.5 0.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAAP01000342.1_2 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family DSBA PF01323.20 AAAP01000344.1_1 - 9e-09 35.4 0.1 9.7e-09 35.3 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAAP01000344.1_1 - 6.7e-05 23.1 0.0 7e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAAP01000344.1_1 - 0.0051 17.2 0.0 0.0052 17.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 AAAP01000344.1_2 - 1.1e-12 48.4 0.1 3e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin ScsC_N PF18312.1 AAAP01000344.1_2 - 1.2e-12 47.4 4.9 1.2e-12 47.4 4.9 1.8 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain DSBA PF01323.20 AAAP01000344.1_2 - 1.2e-09 38.2 0.0 3.2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AAAP01000344.1_2 - 0.0037 17.7 0.0 0.0077 16.7 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AAAP01000344.1_2 - 0.11 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like zf-Di19 PF05605.12 AAAP01000344.1_2 - 0.12 12.6 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding p450 PF00067.22 AAAP01000345.1_2 - 0.00094 18.0 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 rve PF00665.26 AAAP01000346.1_1 - 9.5e-10 38.7 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AAAP01000346.1_1 - 1.8e-06 27.8 0.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Mu transposase, C-terminal rve_3 PF13683.6 AAAP01000346.1_1 - 0.0022 17.7 0.0 0.29 10.9 0.0 2.2 1 1 1 2 2 2 2 Integrase core domain Acetyltransf_1 PF00583.25 AAAP01000347.1_1 - 2.1e-08 34.4 0.0 2.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAAP01000347.1_1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 AAAP01000347.1_1 - 0.00057 20.3 0.0 0.0008 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01000347.1_1 - 0.0015 18.5 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01000347.1_1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAAP01000347.1_1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 AAAP01000350.1_1 - 1.1e-33 116.4 0.3 1.3e-33 116.1 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01000350.1_1 - 3e-26 92.4 0.2 3.9e-26 92.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01000350.1_1 - 6.3e-12 45.8 0.3 7.7e-12 45.5 0.3 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 AAAP01000350.1_1 - 0.00083 19.3 0.8 0.034 14.1 0.3 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 AAAP01000350.1_1 - 0.05 13.5 0.2 0.067 13.1 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AAAP01000350.1_1 - 0.052 14.1 0.3 0.12 13.0 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SdiA-regulated PF06977.11 AAAP01000351.1_2 - 1e-62 211.6 0.0 1.1e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 SdiA-regulated Phytase-like PF13449.6 AAAP01000351.1_2 - 1.6e-08 34.8 0.0 0.00076 19.5 0.0 2.1 2 0 0 2 2 2 2 Esterase-like activity of phytase Sulf_transp PF04143.14 AAAP01000352.1_1 - 0.00065 19.3 3.0 0.00065 19.3 3.0 2.1 1 1 0 2 2 2 1 Sulphur transport DUF3382 PF11862.8 AAAP01000352.1_1 - 2.6 8.4 9.2 3.4 8.0 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF4229 PF14012.6 AAAP01000352.1_1 - 4.6 7.4 12.5 0.063 13.4 4.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) TM_helix PF05552.12 AAAP01000352.1_1 - 8 6.5 8.1 11 6.1 0.4 3.1 3 0 0 3 3 3 0 Conserved TM helix Sulf_transp PF04143.14 AAAP01000352.1_2 - 1e-06 28.6 8.9 1.3e-06 28.3 8.9 1.2 1 0 0 1 1 1 1 Sulphur transport Gram_pos_anchor PF00746.21 AAAP01000352.1_2 - 5 7.2 8.2 6 6.9 0.5 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CDPS PF16715.5 AAAP01000353.1_1 - 0.11 12.1 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase GTP_EFTU PF00009.27 AAAP01000353.1_2 - 1.1e-53 181.7 0.1 1.3e-53 181.5 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAAP01000353.1_2 - 5.1e-07 29.8 0.0 8.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 AAAP01000353.1_2 - 4.3e-05 23.2 0.0 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 AAAP01000353.1_2 - 0.00017 21.6 0.0 0.00039 20.4 0.0 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain Septin PF00735.18 AAAP01000353.1_2 - 0.00025 20.4 0.1 0.087 12.1 0.0 2.1 2 0 0 2 2 2 2 Septin SRPRB PF09439.10 AAAP01000353.1_2 - 0.0022 17.4 0.1 0.011 15.2 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 AAAP01000353.1_2 - 0.0029 17.8 0.0 0.016 15.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 AAAP01000353.1_2 - 0.0033 17.0 0.6 0.024 14.2 0.4 2.3 1 1 0 2 2 2 1 Ferrous iron transport protein B DAO PF01266.24 AAAP01000354.1_1 - 3.8e-17 62.9 0.1 4.4e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01000354.1_1 - 2.1e-08 34.2 0.5 5.4e-08 32.9 0.5 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAAP01000354.1_1 - 1.9e-05 24.1 0.6 2.5e-05 23.7 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01000354.1_1 - 2.8e-05 23.5 0.0 3.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01000354.1_1 - 3.7e-05 23.0 1.5 5e-05 22.6 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AAAP01000354.1_1 - 0.00017 21.3 0.5 0.00023 20.8 0.5 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 AAAP01000354.1_1 - 0.00035 20.6 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AAAP01000354.1_1 - 0.00055 19.6 0.4 0.0007 19.2 0.4 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 AAAP01000354.1_1 - 0.00066 19.2 0.0 0.00092 18.8 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 AAAP01000354.1_1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 AAAP01000354.1_1 - 0.0015 19.1 1.6 0.0021 18.6 1.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01000354.1_1 - 0.0018 17.6 0.2 0.0023 17.3 0.2 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAAP01000354.1_1 - 0.0023 17.2 0.9 0.003 16.9 0.9 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 AAAP01000354.1_1 - 0.0023 18.3 0.1 0.0023 18.3 0.1 1.2 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 AAAP01000354.1_1 - 0.0028 17.0 0.1 0.0037 16.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAAP01000354.1_1 - 0.011 15.7 1.2 0.014 15.3 1.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 AAAP01000354.1_1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase IlvN PF07991.12 AAAP01000354.1_1 - 0.02 14.5 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 AAAP01000354.1_1 - 0.025 13.3 0.8 0.031 13.0 0.8 1.1 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 AAAP01000354.1_1 - 0.03 14.8 0.1 0.036 14.6 0.1 1.4 1 1 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 AAAP01000354.1_1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 AAAP01000354.1_1 - 0.038 13.4 0.2 0.05 13.1 0.2 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 AAAP01000354.1_1 - 0.11 12.8 0.4 0.17 12.2 0.4 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 AAAP01000354.1_1 - 0.11 12.6 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 AAAP01000354.1_1 - 0.12 12.7 0.6 0.18 12.1 0.6 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 AAAP01000354.1_1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) GIDA PF01134.22 AAAP01000354.1_1 - 0.15 11.1 2.2 0.18 10.8 2.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.25 AAAP01000354.1_1 - 0.24 10.8 0.4 0.33 10.4 0.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DUF3729 PF12526.8 AAAP01000355.1_2 - 0.024 16.2 0.2 0.03 15.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) CcmB PF03379.13 AAAP01000355.1_3 - 2.3e-07 30.6 2.8 2.4e-07 30.5 2.8 1.0 1 0 0 1 1 1 1 CcmB protein DUF4342 PF14242.6 AAAP01000355.1_3 - 6.9 6.7 7.0 9.4 6.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) SBBP PF06739.11 AAAP01000357.1_1 - 1.9e-06 27.8 1.3 0.00016 21.6 0.5 2.5 2 0 0 2 2 2 2 Beta-propeller repeat PTS-HPr PF00381.19 AAAP01000358.1_1 - 7.9e-20 70.9 0.6 1.4e-19 70.1 0.6 1.4 1 0 0 1 1 1 1 PTS HPr component phosphorylation site EIIA-man PF03610.16 AAAP01000358.1_1 - 3.7e-16 59.4 0.2 7e-16 58.5 0.2 1.4 1 0 0 1 1 1 1 PTS system fructose IIA component TetR_N PF00440.23 AAAP01000358.1_2 - 1.8e-11 43.6 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_29 PF13551.6 AAAP01000358.1_2 - 0.003 17.6 0.1 0.041 13.9 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01000358.1_2 - 0.02 14.7 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AraC PF00165.23 AAAP01000358.1_2 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_C_14 PF17754.1 AAAP01000358.1_2 - 0.18 11.7 7.5 0.24 11.3 6.5 1.7 1 1 0 1 1 1 0 MftR C-terminal domain AAA_lid_2 PF17863.1 AAAP01000358.1_2 - 2.1 8.3 9.9 8.2 6.4 0.7 3.5 2 2 1 3 3 3 0 AAA lid domain Na_sulph_symp PF00939.19 AAAP01000359.1_1 - 3.9e-08 32.8 0.9 4.4e-08 32.6 0.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region ATP-synt_I PF03899.15 AAAP01000359.1_1 - 0.15 12.5 5.9 0.76 10.2 0.4 2.1 1 1 1 2 2 2 0 ATP synthase I chain HPPK PF01288.20 AAAP01000360.1_1 - 0.005 17.3 0.0 0.005 17.3 0.0 1.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SMC_N PF02463.19 AAAP01000362.1_1 - 2.3e-39 135.1 0.0 2.8e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01000362.1_1 - 3.9e-16 60.2 0.0 4.8e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01000362.1_1 - 1.5e-09 38.0 0.0 1.7e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01000362.1_1 - 1.4e-07 31.7 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01000362.1_1 - 8.7e-07 28.6 0.1 1.7e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AAAP01000362.1_1 - 0.00041 20.0 0.1 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AAAP01000362.1_1 - 0.012 16.1 0.1 0.02 15.4 0.1 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AAAP01000362.1_1 - 0.02 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAAP01000362.1_1 - 0.066 12.9 0.5 0.11 12.1 0.1 1.5 2 0 0 2 2 2 0 AAA domain DUF2813 PF11398.8 AAAP01000362.1_1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) NDK PF00334.19 AAAP01000362.1_2 - 5.9e-33 113.7 0.0 7.2e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase S4 PF01479.25 AAAP01000363.1_2 - 1e-07 31.6 0.3 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 2 S4 domain GTP_EFTU PF00009.27 AAAP01000363.1_3 - 2.6e-16 59.7 0.5 2.8e-16 59.6 0.5 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAAP01000363.1_3 - 0.066 13.3 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_S14 PF00253.21 AAAP01000365.1_1 - 1.2e-23 82.6 0.5 1.8e-23 82.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e RecG_N PF17190.4 AAAP01000365.1_1 - 0.11 13.3 1.7 0.13 13.0 1.7 1.1 1 0 0 1 1 1 0 RecG N-terminal helical domain Ribosomal_L5_C PF00673.21 AAAP01000365.1_2 - 1.5e-40 137.3 0.0 1.7e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 ribosomal L5P family C-terminus NIR_SIR PF01077.22 AAAP01000366.1_1 - 4.3e-33 114.1 0.1 7.9e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01000366.1_1 - 8.4e-15 54.4 0.0 1.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain adh_short PF00106.25 AAAP01000367.1_1 - 2.7e-57 193.4 3.6 3.5e-57 193.0 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01000367.1_1 - 9.9e-57 192.2 11.4 1.4e-56 191.7 11.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01000367.1_1 - 1.5e-12 47.8 4.8 2.3e-12 47.2 4.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01000367.1_1 - 2.4e-09 37.0 0.7 3e-09 36.7 0.7 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01000367.1_1 - 2.9e-07 30.5 9.4 5.6e-07 29.6 9.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 AAAP01000367.1_1 - 0.00016 21.9 1.3 0.00061 20.0 0.5 2.2 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 AAAP01000367.1_1 - 0.00066 19.4 1.1 0.0014 18.3 0.2 2.0 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAAP01000367.1_1 - 0.001 19.3 0.1 0.0031 17.7 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATPgrasp_N PF18130.1 AAAP01000367.1_1 - 0.0013 19.2 0.3 0.0039 17.7 0.3 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain THF_DHG_CYH_C PF02882.19 AAAP01000367.1_1 - 0.0017 17.7 0.9 0.003 16.9 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 AAAP01000367.1_1 - 0.074 12.9 2.6 0.12 12.2 1.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 AAAP01000367.1_1 - 0.63 9.5 3.1 12 5.4 2.1 2.2 2 0 0 2 2 2 0 NmrA-like family FliX PF10768.9 AAAP01000368.1_1 - 8e-39 133.3 1.2 9.3e-39 133.1 1.2 1.0 1 0 0 1 1 1 1 Class II flagellar assembly regulator HAD PF12710.7 AAAP01000369.1_2 - 1.2e-10 42.1 0.0 1.8e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Vsr PF03852.15 AAAP01000369.1_2 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Amidohydro_3 PF07969.11 AAAP01000370.1_2 - 7.1e-49 167.5 0.0 2e-48 166.1 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family PALP PF00291.25 AAAP01000371.1_1 - 5.7e-05 22.7 0.0 7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.6 AAAP01000371.1_1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Oxidored_FMN PF00724.20 AAAP01000372.1_1 - 1.6e-31 109.9 0.0 1.9e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldedh PF00171.22 AAAP01000372.1_2 - 6.4e-39 133.7 0.0 7.2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Resolvase PF00239.21 AAAP01000373.1_1 - 0.0004 20.5 1.0 0.00053 20.1 0.6 1.4 2 0 0 2 2 2 1 Resolvase, N terminal domain Phage_Nu1 PF07471.12 AAAP01000373.1_1 - 0.03 14.1 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Adeno_E1A PF02703.14 AAAP01000374.1_1 - 0.15 11.6 2.9 0.24 11.0 2.9 1.2 1 0 0 1 1 1 0 Early E1A protein Polyketide_cyc2 PF10604.9 AAAP01000374.1_2 - 0.0079 16.5 0.7 0.0085 16.4 0.7 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HTH_Tnp_1 PF01527.20 AAAP01000374.1_2 - 0.034 14.5 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 Transposase GidB PF02527.15 AAAP01000375.1_1 - 1.4e-30 106.0 0.0 1.8e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 AAAP01000375.1_1 - 0.0057 16.2 0.0 0.01 15.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 AAAP01000375.1_1 - 0.029 13.9 0.0 0.062 12.8 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 AAAP01000375.1_1 - 0.098 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DDE_Tnp_IS66 PF03050.14 AAAP01000376.1_1 - 4.8e-54 183.7 0.0 5.8e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 AAAP01000376.1_1 - 0.015 15.6 0.1 0.16 12.2 0.1 2.4 1 1 0 1 1 1 0 IS66 C-terminal element Phage_holin_3_6 PF07332.11 AAAP01000377.1_1 - 0.085 12.9 5.3 0.087 12.9 5.3 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SgrT PF15894.5 AAAP01000378.1_2 - 0.052 13.5 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Methyltransf_23 PF13489.6 AAAP01000380.1_1 - 0.0029 17.4 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01000380.1_1 - 0.0041 17.7 0.0 0.0062 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01000380.1_1 - 0.076 13.8 0.0 0.13 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Band_7 PF01145.25 AAAP01000381.1_1 - 7.2e-22 78.2 0.1 7.9e-22 78.1 0.1 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family CsrA PF02599.16 AAAP01000381.1_1 - 0.0073 16.2 0.4 0.014 15.3 0.4 1.4 1 0 0 1 1 1 1 Global regulator protein family DUF1416 PF07210.12 AAAP01000381.1_1 - 0.019 14.8 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) RST PF12174.8 AAAP01000381.1_1 - 0.054 13.4 0.2 0.089 12.7 0.2 1.3 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Band_7_1 PF13421.6 AAAP01000381.1_1 - 0.078 12.7 0.1 0.11 12.2 0.1 1.3 1 1 0 1 1 1 0 SPFH domain-Band 7 family VanZ PF04892.12 AAAP01000382.1_1 - 3.9e-17 63.1 2.4 5.9e-17 62.5 0.7 2.0 2 0 0 2 2 2 1 VanZ like family RDD PF06271.12 AAAP01000382.1_1 - 9.8 6.4 18.0 0.11 12.7 8.9 2.1 2 1 0 2 2 2 0 RDD family Glyco_trans_2_3 PF13632.6 AAAP01000383.1_1 - 5.6e-23 81.9 3.6 8.1e-23 81.4 3.6 1.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 AAAP01000383.1_1 - 2.8e-14 53.6 0.1 3.6e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AAAP01000383.1_1 - 4.4e-05 23.0 0.1 6.4e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 HATPase_c PF02518.26 AAAP01000384.1_1 - 2.6e-16 60.1 0.0 3.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01000384.1_1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01000385.1_2 - 2.6e-11 44.0 0.0 2.8e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Flavodoxin_2 PF02525.17 AAAP01000386.1_1 - 2.3e-22 79.7 0.0 2.5e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAAP01000386.1_1 - 7.9e-11 41.9 0.0 8.8e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 AAAP01000386.1_1 - 0.17 11.6 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin SLT_2 PF13406.6 AAAP01000386.1_2 - 1.7e-20 73.4 0.0 2.4e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 AAAP01000386.1_2 - 2.3e-13 50.1 0.2 4.1e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 AAAP01000386.1_2 - 0.0018 18.6 0.0 0.0079 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 AAAP01000386.1_2 - 0.0089 16.3 0.2 0.021 15.1 0.2 1.6 1 0 0 1 1 1 1 Predicted Peptidoglycan domain AFG1_ATPase PF03969.16 AAAP01000388.1_1 - 2.8e-07 29.8 0.0 3.2e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase Xan_ur_permease PF00860.20 AAAP01000389.1_1 - 2.1e-52 178.1 22.8 2.6e-52 177.9 22.8 1.0 1 0 0 1 1 1 1 Permease family DUF1120 PF06551.12 AAAP01000389.1_1 - 0.087 13.0 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Glyoxalase_6 PF18029.1 AAAP01000390.1_1 - 5.5e-14 52.9 0.4 7.2e-14 52.5 0.4 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain KIAA1430 PF13879.6 AAAP01000391.1_2 - 0.072 13.9 0.2 0.11 13.3 0.2 1.3 1 0 0 1 1 1 0 KIAA1430 homologue APG6_N PF17675.1 AAAP01000391.1_2 - 4.1 7.9 7.5 33 5.0 7.4 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Rhomboid PF01694.22 AAAP01000392.1_1 - 1.3e-13 51.2 0.9 1.3e-13 51.2 0.9 1.0 1 0 0 1 1 1 1 Rhomboid family Hydrolase_2 PF07486.12 AAAP01000393.1_2 - 3.8e-05 24.5 0.0 7.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Cell Wall Hydrolase GATase PF00117.28 AAAP01000395.1_1 - 3.3e-19 69.4 0.0 4.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01000395.1_1 - 1.9e-06 27.8 0.2 6e-06 26.2 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AAAP01000395.1_1 - 0.00034 20.5 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 AAAP01000395.1_1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AAAP01000395.1_1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family His_biosynth PF00977.21 AAAP01000395.1_2 - 8.1e-09 35.3 0.0 9.3e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldo_ket_red PF00248.21 AAAP01000396.1_1 - 8.5e-46 156.5 0.0 9.9e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family APS_kinase PF01583.20 AAAP01000398.1_1 - 3.4e-18 66.0 0.0 3.6e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase APS_kinase PF01583.20 AAAP01000398.1_2 - 0.00028 20.8 0.1 0.00028 20.8 0.1 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase Peripla_BP_3 PF13377.6 AAAP01000399.1_1 - 1.6e-34 119.7 0.8 2.2e-33 115.9 0.1 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAAP01000399.1_1 - 6.5e-20 71.7 0.0 8.1e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AAAP01000399.1_1 - 5.2e-06 26.2 0.0 6.3e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein domain PP-binding PF00550.25 AAAP01000400.1_1 - 1.2e-12 48.0 0.1 7.4e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 AAAP01000400.1_1 - 4.4e-10 40.4 0.1 2.9e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 AAAP01000400.1_1 - 0.0031 17.1 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Hydrolase PF00702.26 AAAP01000402.1_1 - 1.1e-45 156.5 6.2 1.6e-45 156.0 6.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01000402.1_1 - 2.6e-07 30.6 1.5 6.4e-05 22.8 0.6 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01000402.1_1 - 1.5e-06 28.8 0.6 3.3e-06 27.6 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PAXNEB PF05625.11 AAAP01000402.1_1 - 0.31 10.1 0.0 0.47 9.5 0.0 1.1 1 0 0 1 1 1 0 PAXNEB protein LuxC PF05893.14 AAAP01000403.1_1 - 1.4e-22 80.3 0.0 1.7e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) AMP-binding PF00501.28 AAAP01000403.1_1 - 0.0016 17.1 0.0 0.034 12.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Thioredoxin PF00085.20 AAAP01000404.1_1 - 8.6e-08 32.1 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Transcrip_reg PF01709.20 AAAP01000406.1_1 - 8.5e-20 71.2 0.2 9.5e-20 71.0 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator Transcrip_reg PF01709.20 AAAP01000406.1_2 - 1.1e-31 110.1 0.1 1.2e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Oxidored_q3 PF00499.20 AAAP01000407.1_1 - 6.1e-20 71.4 2.8 7.7e-20 71.1 2.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ABC_membrane PF00664.23 AAAP01000408.1_1 - 4.4e-05 23.3 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01000408.1_2 - 3e-09 37.5 0.0 3.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01000408.1_2 - 0.00063 19.4 0.1 0.00086 19.0 0.1 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01000408.1_2 - 0.00089 19.1 0.1 0.00096 19.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 AAAP01000408.1_2 - 0.0025 17.9 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AAAP01000408.1_2 - 0.005 17.3 0.2 0.0053 17.2 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01000408.1_2 - 0.015 15.2 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 AAAP01000408.1_2 - 0.02 15.0 0.4 0.026 14.6 0.4 1.2 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 AAAP01000408.1_2 - 0.046 13.1 0.1 0.051 12.9 0.1 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.13 AAAP01000408.1_2 - 0.047 12.8 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 AAAP01000408.1_2 - 0.067 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 AAAP01000408.1_2 - 0.097 12.8 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAAP01000408.1_2 - 0.11 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IIGP PF05049.13 AAAP01000408.1_2 - 0.11 11.5 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PRK PF00485.18 AAAP01000408.1_2 - 0.17 11.6 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 AAAP01000408.1_2 - 0.18 11.7 0.3 0.27 11.1 0.3 1.2 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAAP01000408.1_2 - 0.23 11.8 0.3 0.36 11.1 0.3 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AAAP01000408.1_2 - 0.25 11.1 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 AAAP01000408.1_2 - 0.3 11.6 0.0 0.32 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAAP01000408.1_2 - 0.7 9.9 1.5 0.96 9.5 1.5 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Polysacc_synt_C PF14667.6 AAAP01000409.1_1 - 0.0024 17.9 5.8 0.0027 17.8 5.8 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain Phage_holin_3_6 PF07332.11 AAAP01000409.1_1 - 0.67 10.0 15.5 0.72 9.9 15.5 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EAL PF00563.20 AAAP01000410.1_1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 EAL domain SlyX PF04102.12 AAAP01000410.1_1 - 0.001 19.6 0.3 0.0068 17.0 0.3 2.2 2 0 0 2 2 2 1 SlyX GcrA PF07750.11 AAAP01000410.1_1 - 0.064 13.7 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator Fib_alpha PF08702.10 AAAP01000410.1_1 - 0.25 11.5 0.0 0.36 11.0 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Response_reg PF00072.24 AAAP01000411.1_1 - 2.9e-26 91.8 0.0 4.1e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01000411.1_1 - 3.1e-10 39.4 0.0 6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01000411.1_1 - 0.00048 19.8 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 NTP_transf_3 PF12804.7 AAAP01000411.1_1 - 0.011 16.1 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain SDH_alpha PF03313.15 AAAP01000412.1_1 - 6.2e-91 304.7 4.2 6.7e-91 304.6 4.2 1.0 1 0 0 1 1 1 1 Serine dehydratase alpha chain Phage_holin_2_4 PF16082.5 AAAP01000412.1_1 - 1.7 8.5 7.4 4.4 7.1 7.4 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like CP_ATPgrasp_2 PF14403.6 AAAP01000413.1_1 - 1.5e-72 244.6 0.0 1.7e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAAP01000413.1_1 - 8.8e-54 182.8 0.0 1e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 A circularly permuted ATPgrasp HTH_5 PF01022.20 AAAP01000414.1_3 - 0.027 14.3 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAAP01000414.1_3 - 0.047 13.6 0.4 1.6 8.7 0.0 2.8 2 1 1 3 3 3 0 MarR family PHY PF00360.20 AAAP01000415.1_1 - 7.8e-21 74.2 0.0 1.2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 AAAP01000415.1_1 - 4.1e-06 27.4 0.0 8.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain FtsX PF02687.21 AAAP01000417.1_1 - 0.0003 21.2 14.1 0.17 12.4 14.1 2.4 1 1 0 1 1 1 1 FtsX-like permease family TMEM239 PF15841.5 AAAP01000417.1_1 - 0.039 13.9 1.2 0.039 13.9 1.2 1.8 1 1 1 2 2 2 0 Transmembrane protein 239 family ABC_tran PF00005.27 AAAP01000417.1_2 - 8.1e-09 36.1 0.1 9.2e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01000417.1_2 - 1.7e-05 24.5 0.4 2.2e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01000417.1_2 - 0.00075 19.4 0.2 0.00079 19.4 0.2 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01000417.1_2 - 0.0055 17.1 0.2 0.0058 17.0 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01000417.1_2 - 0.01 15.6 0.9 0.012 15.3 0.9 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01000417.1_2 - 0.012 15.2 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 AAAP01000417.1_2 - 0.029 14.2 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 AAAP01000417.1_2 - 0.089 12.5 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 AAAP01000417.1_2 - 0.11 12.9 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01000417.1_2 - 0.17 12.0 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hist_deacetyl PF00850.19 AAAP01000419.1_2 - 9.4e-25 87.7 0.0 1e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Hist_deacetyl PF00850.19 AAAP01000419.1_3 - 2.4e-49 168.5 1.1 3.3e-49 168.0 1.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Lactamase_B PF00753.27 AAAP01000420.1_1 - 1.3e-12 48.1 0.2 1.5e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01000420.1_1 - 6.3e-05 22.6 0.0 7.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 AAAP01000421.1_1 - 5.1e-21 75.0 30.7 7.8e-21 74.4 30.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01000421.1_1 - 1.4e-08 34.1 4.4 1.4e-08 34.1 4.4 1.8 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 AAAP01000421.1_1 - 0.00039 19.4 9.2 0.0013 17.7 6.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3325 PF11804.8 AAAP01000421.1_1 - 0.025 14.7 3.0 0.025 14.7 3.0 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3325) MFS_3 PF05977.13 AAAP01000421.1_1 - 0.42 8.9 20.1 0.21 9.9 6.7 2.3 3 0 0 3 3 3 0 Transmembrane secretion effector GST_N_3 PF13417.6 AAAP01000422.1_1 - 5.5e-10 39.5 0.0 6.5e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01000422.1_1 - 9.2e-10 38.7 0.0 1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01000422.1_1 - 2.3e-09 37.5 0.0 2.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HMG_box_2 PF09011.10 AAAP01000422.1_2 - 0.0041 17.7 1.1 0.0041 17.7 1.1 1.6 2 1 0 2 2 2 1 HMG-box domain ResB PF05140.14 AAAP01000423.1_1 - 3.2e-09 36.1 0.2 4.2e-09 35.7 0.2 1.2 1 0 0 1 1 1 1 ResB-like family RAMPs PF03787.15 AAAP01000423.1_1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 RAMP superfamily DsbD PF02683.15 AAAP01000423.1_2 - 1.4e-23 83.9 5.2 1.6e-23 83.7 5.2 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AAAP01000423.1_2 - 0.0006 19.8 12.5 0.0013 18.7 12.5 1.5 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region SAICAR_synt PF01259.18 AAAP01000424.1_1 - 5.8e-07 29.4 0.1 5.8e-07 29.4 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase HTH_DeoR PF08220.12 AAAP01000425.1_1 - 1.4e-18 66.4 0.7 2.8e-18 65.4 0.7 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain DeoRC PF00455.22 AAAP01000425.1_1 - 2.6e-17 63.2 0.1 3.7e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_11 PF08279.12 AAAP01000425.1_1 - 2e-06 27.7 0.2 4e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AAAP01000425.1_1 - 1.5e-05 24.7 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family GntR PF00392.21 AAAP01000425.1_1 - 1.9e-05 24.2 0.7 4.7e-05 22.9 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAAP01000425.1_1 - 8.5e-05 22.0 1.5 0.00033 20.2 0.1 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAAP01000425.1_1 - 0.00017 21.4 2.4 0.00042 20.2 0.2 2.3 2 0 0 2 2 2 1 MarR family HTH_12 PF08461.10 AAAP01000425.1_1 - 0.00023 21.1 0.6 0.00052 19.9 0.5 1.7 1 1 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_20 PF12840.7 AAAP01000425.1_1 - 0.00044 20.3 4.0 0.001 19.1 0.4 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_36 PF13730.6 AAAP01000425.1_1 - 0.00051 19.9 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01000425.1_1 - 0.0018 18.0 2.2 0.0028 17.4 1.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain FaeA PF04703.12 AAAP01000425.1_1 - 0.0032 17.8 0.0 0.0065 16.8 0.0 1.5 1 0 0 1 1 1 1 FaeA-like protein Rrf2 PF02082.20 AAAP01000425.1_1 - 0.0061 16.9 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01000425.1_1 - 0.0077 16.1 0.5 0.0077 16.1 0.5 2.5 3 1 1 4 4 4 1 MarR family TrmB PF01978.19 AAAP01000425.1_1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AAAP01000425.1_1 - 0.013 15.4 1.6 0.029 14.3 0.3 2.1 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01000425.1_1 - 0.02 14.3 0.1 0.053 12.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Put_DNA-bind_N PF06971.13 AAAP01000425.1_1 - 0.029 14.4 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus HTH_28 PF13518.6 AAAP01000425.1_1 - 0.029 14.5 0.2 0.088 13.0 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RepL PF05732.11 AAAP01000425.1_1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Fe_dep_repress PF01325.19 AAAP01000425.1_1 - 0.12 12.6 0.1 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain DUF2250 PF10007.9 AAAP01000425.1_1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_6 PF01418.17 AAAP01000425.1_1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Amidase PF01425.21 AAAP01000425.1_2 - 0.00027 20.0 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Amidase NTP_transf_9 PF04248.12 AAAP01000428.1_1 - 1.4e-19 69.7 0.0 1.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) SGL PF08450.12 AAAP01000429.1_1 - 1.1e-32 113.6 0.0 1.2e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Actino_peptide PF14408.6 AAAP01000429.1_1 - 0.0089 16.1 0.3 15 5.8 0.0 3.3 3 0 0 3 3 3 2 Ribosomally synthesised peptide in actinomycetes Str_synth PF03088.16 AAAP01000429.1_1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Strictosidine synthase NIR_SIR_ferr PF03460.17 AAAP01000430.1_1 - 0.00033 20.4 0.0 0.00039 20.2 0.0 1.1 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain CobN-Mg_chel PF02514.16 AAAP01000430.1_2 - 1.4e-33 115.8 0.0 1.7e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase HTH_32 PF13565.6 AAAP01000430.1_2 - 9.4 6.9 10.3 0.45 11.2 0.6 2.7 3 0 0 3 3 3 0 Homeodomain-like domain PepSY_TM PF03929.16 AAAP01000432.1_1 - 0.00035 20.3 0.2 0.00035 20.3 0.2 1.1 1 0 0 1 1 1 1 PepSY-associated TM region OEP PF02321.18 AAAP01000432.1_2 - 6e-08 32.7 8.3 0.0012 18.7 2.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein MltA PF03562.17 AAAP01000433.1_1 - 1.4e-20 74.0 0.0 1.7e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 MltA specific insert domain 3D PF06725.11 AAAP01000433.1_1 - 1.3e-16 60.5 0.1 2.6e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 3D domain DUF4880 PF16220.5 AAAP01000433.1_1 - 0.034 14.0 1.3 0.07 13.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Ald_Xan_dh_C2 PF02738.18 AAAP01000434.1_1 - 2e-24 86.0 0.0 2.5e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01000434.1_1 - 0.024 15.0 0.2 1.6 9.1 0.3 2.6 1 1 1 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Aminotran_5 PF00266.19 AAAP01000435.1_1 - 8.9e-08 31.5 0.0 9.5e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V tRNA_Me_trans PF03054.16 AAAP01000435.1_2 - 3.2e-27 95.3 0.0 3.4e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Sel1 PF08238.12 AAAP01000436.1_1 - 6.2e-28 96.6 25.8 1.9e-10 41.1 0.4 6.3 6 0 0 6 6 6 6 Sel1 repeat DUF2540 PF10802.8 AAAP01000436.1_1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) AA_permease_2 PF13520.6 AAAP01000436.1_2 - 0.14 11.0 5.0 0.15 10.9 5.0 1.0 1 0 0 1 1 1 0 Amino acid permease B277 PF17623.2 AAAP01000436.1_2 - 0.28 10.2 1.0 0.29 10.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function AA_permease PF00324.21 AAAP01000436.1_2 - 0.62 8.6 7.1 0.68 8.5 7.1 1.0 1 0 0 1 1 1 0 Amino acid permease LysR_substrate PF03466.20 AAAP01000437.1_2 - 3.6e-18 65.7 0.1 5.6e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01000437.1_2 - 2.3e-15 56.3 1.4 5.4e-15 55.1 1.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family adh_short_C2 PF13561.6 AAAP01000439.1_1 - 1.1e-08 35.0 0.6 1.7e-07 31.0 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HSP20 PF00011.21 AAAP01000442.1_1 - 8.7e-07 29.0 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 AAAP01000442.1_2 - 2.1e-23 82.4 0.8 2.7e-23 82.0 0.8 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01000442.1_2 - 2.1e-10 40.0 0.1 3.4e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 AAAP01000442.1_2 - 0.023 15.1 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain FKBP26_C PF18046.1 AAAP01000442.1_2 - 0.086 13.0 0.2 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal ETC_C1_NDUFA4 PF04800.12 AAAP01000442.1_3 - 4.5e-18 65.3 0.0 7.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region SNARE_assoc PF09335.11 AAAP01000442.1_3 - 0.07 13.6 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Glyco_hydro_25 PF01183.20 AAAP01000443.1_1 - 4.4e-48 163.8 0.0 5.2e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 MFS_1 PF07690.16 AAAP01000444.1_2 - 4.4e-10 39.0 35.8 8.8e-10 38.0 35.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Molybdopterin PF00384.22 AAAP01000445.1_1 - 5.8e-14 51.9 0.0 7.8e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase GST_C_2 PF13410.6 AAAP01000446.1_2 - 4.5e-13 49.0 0.1 6e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAAP01000446.1_2 - 3.8e-06 27.0 0.0 4.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAAP01000446.1_2 - 2.5e-05 24.4 0.0 3.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAAP01000446.1_2 - 0.00062 19.5 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Telomere_Sde2_2 PF13297.6 AAAP01000446.1_2 - 0.19 11.4 0.1 0.41 10.3 0.1 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal Sugar_tr PF00083.24 AAAP01000447.1_1 - 9.1e-08 31.4 0.6 1.1e-07 31.1 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAAP01000447.1_1 - 1.2e-06 27.7 15.4 1.5e-06 27.4 15.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 AAAP01000449.1_1 - 9.1e-08 32.3 0.0 2.5e-07 30.9 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 AAAP01000449.1_1 - 3.2e-06 27.2 0.0 6.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 AAAP01000449.1_1 - 0.00019 21.8 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01000449.1_1 - 0.00064 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAAP01000449.1_1 - 0.0021 18.1 0.1 0.0043 17.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01000449.1_1 - 0.095 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.7 AAAP01000449.1_1 - 0.13 12.4 4.1 0.34 11.1 0.0 2.7 3 1 1 4 4 4 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01000449.1_2 - 0.08 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DinB_2 PF12867.7 AAAP01000450.1_1 - 1.3e-06 28.9 12.0 5.3e-06 27.0 12.0 1.9 1 1 0 1 1 1 1 DinB superfamily IlvGEDA_leader PF08046.11 AAAP01000450.1_2 - 0.14 11.6 0.2 0.2 11.1 0.2 1.2 1 0 0 1 1 1 0 IlvGEDA operon leader peptide DUF2336 PF10098.9 AAAP01000451.1_1 - 6.3e-09 35.7 3.9 6.3e-09 35.7 3.9 2.8 3 1 1 4 4 4 1 Uncharacterised protein conserved in bacteria (DUF2336) DsbD PF02683.15 AAAP01000452.1_1 - 0.017 15.0 6.9 0.027 14.3 6.9 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Cyanate_lyase PF02560.14 AAAP01000453.1_1 - 9.8e-13 47.8 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain TamB PF04357.13 AAAP01000453.1_2 - 3.9e-28 98.8 0.0 4.4e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 TamB, inner membrane protein subunit of TAM complex YadA_anchor PF03895.15 AAAP01000453.1_2 - 0.00017 21.7 4.4 0.015 15.4 3.1 3.0 2 1 0 2 2 2 1 YadA-like membrane anchor domain Response_reg PF00072.24 AAAP01000455.1_1 - 1.8e-17 63.5 0.0 2.1e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DoxX PF07681.12 AAAP01000456.1_1 - 7e-07 29.7 4.9 7e-07 29.7 4.9 1.5 2 0 0 2 2 2 1 DoxX BtrH_N PF14399.6 AAAP01000456.1_1 - 0.098 12.9 0.1 0.098 12.9 0.1 1.2 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal TolA_bind_tri PF16331.5 AAAP01000457.1_2 - 0.16 12.1 3.4 2.9 8.0 0.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4096 PF13340.6 AAAP01000458.1_1 - 2.4e-23 82.1 1.8 3e-23 81.8 1.8 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) AsmA_2 PF13502.6 AAAP01000459.1_1 - 1.2e-07 31.5 0.3 2.1e-07 30.7 0.3 1.4 1 1 0 1 1 1 1 AsmA-like C-terminal region AsmA_1 PF13109.6 AAAP01000459.1_1 - 0.0054 16.2 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 AsmA-like C-terminal region Met_synt_B12 PF02965.17 AAAP01000460.1_1 - 9.7e-60 202.3 0.0 1.4e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain TspO_MBR PF03073.15 AAAP01000461.1_2 - 6.2e-37 126.7 19.1 7e-37 126.5 19.1 1.0 1 0 0 1 1 1 1 TspO/MBR family Sulfate_transp PF00916.20 AAAP01000462.1_1 - 4.8e-46 157.2 20.7 2.2e-26 92.5 4.1 2.0 1 1 1 2 2 2 2 Sulfate permease family MFS_MOT1 PF16983.5 AAAP01000462.1_1 - 9.7e-07 29.2 28.5 4.2e-05 23.9 6.7 3.3 2 1 1 3 3 3 3 Molybdate transporter of MFS superfamily HCO3_cotransp PF00955.21 AAAP01000462.1_1 - 0.18 10.6 8.2 0.74 8.6 2.2 2.2 2 0 0 2 2 2 0 HCO3- transporter family MacB_PCD PF12704.7 AAAP01000463.1_1 - 0.00063 20.2 3.1 0.0007 20.0 3.1 1.1 1 0 0 1 1 1 1 MacB-like periplasmic core domain iPGM_N PF06415.13 AAAP01000465.1_2 - 0.25 10.8 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) HisKA_3 PF07730.13 AAAP01000466.1_1 - 4.5e-08 33.5 1.9 4.5e-08 33.5 1.9 2.0 2 0 0 2 2 2 1 Histidine kinase HAMP PF00672.25 AAAP01000466.1_1 - 0.0061 16.9 0.4 0.03 14.7 0.0 2.4 3 0 0 3 3 3 1 HAMP domain TRCF PF03461.15 AAAP01000466.1_1 - 0.046 14.1 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 TRCF domain DUF3015 PF11220.8 AAAP01000466.1_1 - 0.076 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Exc PF07825.11 AAAP01000467.1_2 - 0.047 13.7 0.3 0.1 12.6 0.3 1.6 1 0 0 1 1 1 0 Excisionase-like protein adh_short_C2 PF13561.6 AAAP01000468.1_1 - 6.4e-11 42.3 0.0 6.6e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SLT PF01464.20 AAAP01000469.1_1 - 4.9e-17 61.6 0.2 6.3e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Cohesin_load PF10345.9 AAAP01000469.1_1 - 0.19 10.1 0.1 0.24 9.8 0.1 1.1 1 0 0 1 1 1 0 Cohesin loading factor Phenol_MetA_deg PF13557.6 AAAP01000470.1_1 - 6.3e-29 101.6 2.3 8.3e-29 101.2 2.3 1.1 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation Methyltransf_25 PF13649.6 AAAP01000471.1_1 - 3.6e-09 37.2 0.0 4.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01000471.1_1 - 5.2e-07 30.2 0.0 7.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01000471.1_1 - 7.6e-06 25.8 0.0 8.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01000471.1_1 - 1.5e-05 24.9 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01000471.1_1 - 6.5e-05 23.6 0.0 8.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAAP01000471.1_1 - 6.8e-05 22.4 0.0 8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01000471.1_1 - 0.00034 20.2 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 AAAP01000471.1_1 - 0.005 16.8 0.0 0.0057 16.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AAAP01000471.1_1 - 0.22 10.6 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 AAAP01000471.1_1 - 0.23 10.8 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 AAAP01000471.1_1 - 0.32 10.2 0.0 0.37 10.0 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NmrA PF05368.13 AAAP01000472.1_2 - 0.025 14.1 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Peptidase_M29 PF02073.15 AAAP01000474.1_1 - 7.3e-48 163.3 0.0 8.6e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) DUF2218 PF09981.9 AAAP01000474.1_2 - 6e-14 52.2 0.0 6.7e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2218) ATP-synt_ab PF00006.25 AAAP01000475.1_1 - 6.8e-44 150.1 0.0 9.3e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AAAP01000475.1_1 - 1.5e-43 148.1 0.7 2.2e-43 147.6 0.7 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Sigma70_r4_2 PF08281.12 AAAP01000476.1_1 - 2.5e-09 36.7 0.1 7.3e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01000476.1_1 - 0.0033 16.9 0.1 0.0073 15.8 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 ORF6N PF10543.9 AAAP01000476.1_1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 ORF6N domain PfkB PF00294.24 AAAP01000477.1_1 - 4.1e-11 42.7 0.0 5.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4238 PF14022.6 AAAP01000478.1_1 - 1.6e-10 41.0 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF952 PF06108.12 AAAP01000479.1_1 - 2.7e-32 110.6 0.0 4.3e-32 110.0 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF952) DHO_dh PF01180.21 AAAP01000479.1_2 - 7.2e-25 87.8 0.0 8.2e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase SURF1 PF02104.15 AAAP01000480.1_2 - 0.0021 18.3 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 SURF1 family HTH_Tnp_1 PF01527.20 AAAP01000483.1_2 - 0.032 14.5 0.1 0.04 14.2 0.1 1.2 1 0 0 1 1 1 0 Transposase DivIC PF04977.15 AAAP01000483.1_2 - 0.062 13.1 0.9 0.067 13.0 0.9 1.1 1 0 0 1 1 1 0 Septum formation initiator HTH_Tnp_1 PF01527.20 AAAP01000483.1_3 - 1.8e-12 47.4 0.1 1.9e-12 47.3 0.1 1.0 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01000483.1_3 - 3.8e-06 26.5 0.0 5.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01000483.1_3 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01000483.1_3 - 0.00016 21.6 0.1 0.00056 19.9 0.0 1.7 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 AAAP01000483.1_3 - 0.0012 18.2 0.0 0.0014 18.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 AAAP01000483.1_3 - 0.0063 16.8 0.0 0.0076 16.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAAP01000483.1_3 - 0.016 15.3 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF2802 PF10975.8 AAAP01000483.1_3 - 0.038 14.1 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) CENP-B_N PF04218.13 AAAP01000483.1_3 - 0.042 13.5 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Sigma70_r4_2 PF08281.12 AAAP01000483.1_3 - 0.053 13.2 0.0 0.08 12.6 0.0 1.4 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_26 PF13443.6 AAAP01000483.1_3 - 0.13 12.7 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CCG PF02754.16 AAAP01000485.1_2 - 5.6e-17 61.7 0.0 6.7e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 Cysteine-rich domain Lactamase_B PF00753.27 AAAP01000486.1_1 - 4.1e-05 23.7 1.3 5.7e-05 23.2 1.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01000486.1_1 - 0.00014 21.5 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Asp_Glu_race PF01177.22 AAAP01000486.1_2 - 2.5e-11 43.9 0.0 3.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Metal_resist PF13801.6 AAAP01000487.1_1 - 0.026 14.7 2.1 0.034 14.3 2.1 1.2 1 0 0 1 1 1 0 Heavy-metal resistance ZnuA PF01297.17 AAAP01000487.1_2 - 1.1e-24 87.3 0.0 1.2e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic PRC PF05239.16 AAAP01000488.1_1 - 2.6e-14 53.0 2.3 3.4e-14 52.7 2.3 1.2 1 0 0 1 1 1 1 PRC-barrel domain MdoG PF04349.12 AAAP01000488.1_2 - 7.8e-18 64.7 0.0 8.8e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG Glyco_hydro_114 PF03537.13 AAAP01000489.1_1 - 3e-36 124.9 0.0 3.8e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF3418 PF11898.8 AAAP01000489.1_2 - 4.6e-16 58.6 0.0 4.6e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) DUF3420 PF11900.8 AAAP01000489.1_2 - 0.037 14.2 0.0 0.042 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) PALP PF00291.25 AAAP01000490.1_1 - 1.3e-25 90.5 0.0 1.4e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3851 PF12962.7 AAAP01000490.1_2 - 0.14 12.4 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Exo_endo_phos PF03372.23 AAAP01000491.1_2 - 4.2e-09 36.3 0.0 5.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Succ_DH_flav_C PF02910.20 AAAP01000492.1_1 - 1e-41 141.9 0.1 1.6e-41 141.3 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Fer2_3 PF13085.6 AAAP01000492.1_2 - 1.1e-16 60.8 0.0 1.3e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TetR_N PF00440.23 AAAP01000493.1_1 - 3.5e-07 29.9 0.1 1.1e-06 28.4 0.1 1.9 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 AAAP01000493.1_1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GGDEF PF00990.21 AAAP01000494.1_1 - 1.1e-28 100.0 0.0 2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_7 PF12860.7 AAAP01000494.1_1 - 5.1e-17 62.1 0.0 1.7e-16 60.4 0.0 1.9 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAAP01000494.1_1 - 5.9e-09 36.2 1.0 3.9e-06 27.1 0.1 2.7 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01000494.1_1 - 2.3e-07 31.0 0.0 0.0034 17.6 0.0 2.5 2 1 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01000494.1_1 - 6.8e-05 22.8 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01000494.1_1 - 0.0023 17.9 0.0 0.0082 16.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AAAP01000494.1_1 - 0.13 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 PAS fold GDC-P PF02347.16 AAAP01000495.1_1 - 1.6e-110 369.9 1.2 1.9e-110 369.7 1.2 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Pyr_redox_2 PF07992.14 AAAP01000496.1_1 - 2.3e-11 43.5 1.6 6.1e-11 42.1 1.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAAP01000496.1_1 - 2.1e-07 30.6 3.0 2.2e-07 30.6 3.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAAP01000496.1_1 - 7e-07 29.7 2.3 2.8e-06 27.8 1.4 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01000496.1_1 - 0.00016 20.9 2.1 0.00016 20.9 2.1 1.2 1 1 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAAP01000496.1_1 - 0.0002 20.8 2.8 0.00024 20.5 2.8 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AAAP01000496.1_1 - 0.00044 20.4 1.7 0.0011 19.1 0.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AAAP01000496.1_1 - 0.00052 19.4 0.2 0.00071 18.9 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01000496.1_1 - 0.0006 19.2 2.5 0.00061 19.1 2.4 1.3 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 AAAP01000496.1_1 - 0.0013 17.9 3.3 0.0013 17.9 3.3 1.4 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 AAAP01000496.1_1 - 0.0028 16.6 1.1 0.0035 16.2 1.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 AAAP01000496.1_1 - 0.0045 15.7 1.2 0.007 15.1 1.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Usp PF00582.26 AAAP01000496.1_1 - 0.031 14.8 2.5 0.041 14.4 0.3 2.0 1 1 1 2 2 2 0 Universal stress protein family NAD_binding_7 PF13241.6 AAAP01000496.1_1 - 0.041 14.3 1.0 0.069 13.6 0.8 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 AAAP01000496.1_1 - 0.064 12.5 1.0 0.089 12.0 0.6 1.4 1 1 0 1 1 1 0 Thi4 family ATPgrasp_N PF18130.1 AAAP01000496.1_1 - 0.25 11.9 2.3 7.1 7.3 0.1 2.5 2 1 0 2 2 2 0 ATP-grasp N-terminal domain PNP_UDP_1 PF01048.20 AAAP01000496.1_2 - 0.005 16.1 2.5 0.005 16.1 2.5 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Glyoxalase PF00903.25 AAAP01000497.1_1 - 7e-15 55.4 0.0 9.5e-13 48.5 0.2 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ribosomal_L31 PF01197.18 AAAP01000497.1_2 - 7.3e-22 77.4 0.0 8.9e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 PAS PF00989.25 AAAP01000498.1_1 - 1e-13 51.3 0.0 7.9e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01000498.1_1 - 2e-10 40.8 0.0 1.5e-06 28.4 0.0 2.4 2 1 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AAAP01000498.1_1 - 7.3e-10 38.6 0.1 0.00022 21.2 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AAAP01000498.1_1 - 7.9e-10 39.0 2.0 9.6e-05 22.6 0.4 2.2 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAAP01000498.1_1 - 1.5e-05 25.2 0.0 0.16 12.3 0.0 2.7 2 1 0 2 2 2 2 PAS fold AAA_16 PF13191.6 AAAP01000499.1_1 - 3.8e-05 24.1 1.0 9.2e-05 22.9 0.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01000499.1_1 - 0.017 15.4 0.2 0.039 14.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01000499.1_1 - 0.022 14.4 0.4 0.032 13.9 0.4 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 AAAP01000499.1_1 - 0.025 15.0 0.1 0.12 12.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01000499.1_1 - 0.14 11.8 8.0 0.1 12.3 6.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 AAAP01000499.1_1 - 0.23 11.8 1.0 0.39 11.1 0.6 1.6 1 1 0 1 1 1 0 AAA domain TPP_enzyme_N PF02776.18 AAAP01000501.1_1 - 2.4e-28 98.9 4.8 3.3e-28 98.4 4.8 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Hydrolase PF00702.26 AAAP01000501.1_1 - 0.03 14.6 1.2 0.78 10.0 0.1 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Amidohydro_1 PF01979.20 AAAP01000502.1_1 - 5.6e-19 68.6 0.1 7.7e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01000502.1_1 - 3.4e-12 46.6 8.9 1.3e-11 44.6 8.9 1.8 1 1 0 1 1 1 1 Amidohydrolase family Anticodon_1 PF08264.13 AAAP01000503.1_2 - 5.8e-20 71.8 0.0 7.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1385 PF07136.11 AAAP01000505.1_1 - 1.7e-69 233.6 1.3 1.9e-69 233.4 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) PRC PF05239.16 AAAP01000506.1_1 - 2.5e-13 49.9 0.4 3.5e-13 49.4 0.4 1.2 1 0 0 1 1 1 1 PRC-barrel domain MFS_1 PF07690.16 AAAP01000506.1_2 - 0.00045 19.3 3.8 0.0006 18.8 3.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01000506.1_2 - 0.0038 16.1 0.1 0.0049 15.8 0.1 1.0 1 0 0 1 1 1 1 MFS_1 like family Peptidase_M20 PF01546.28 AAAP01000509.1_1 - 5.2e-12 45.9 0.0 5.6e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAAP01000509.1_1 - 2.4e-10 40.3 0.0 5.7e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Glycos_transf_2 PF00535.26 AAAP01000510.1_1 - 0.0007 19.5 0.0 0.00095 19.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 PGM_PMM_I PF02878.16 AAAP01000510.1_1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF853 PF05872.12 AAAP01000514.1_1 - 1.5e-110 370.2 0.0 2e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 AAAP01000514.1_1 - 8e-08 32.6 0.0 1e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AAAP01000514.1_1 - 0.00024 20.5 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 AAAP01000514.1_1 - 0.0081 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AAAP01000514.1_1 - 0.012 15.3 0.2 0.022 14.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AAAP01000514.1_1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AAAP01000514.1_1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAAP01000514.1_1 - 0.039 13.0 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 AAAP01000514.1_1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01000514.1_1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M20 PF01546.28 AAAP01000515.1_1 - 2.4e-09 37.2 0.2 3e-09 36.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1158 PF06643.11 AAAP01000516.1_1 - 0.0026 18.3 0.1 0.0034 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1158) BPD_transp_1 PF00528.22 AAAP01000516.1_1 - 0.0046 16.7 4.7 0.0052 16.5 4.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component PspC PF04024.12 AAAP01000516.1_1 - 0.39 10.6 2.5 0.99 9.3 0.3 2.1 2 0 0 2 2 2 0 PspC domain Ferric_reduct PF01794.19 AAAP01000517.1_1 - 2.2e-15 56.9 10.2 4e-15 56.0 10.2 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 AAAP01000517.1_1 - 5.4e-05 23.8 0.0 0.001 19.7 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AAAP01000517.1_1 - 0.0046 17.1 0.0 4.2 7.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain ABC_membrane PF00664.23 AAAP01000520.1_1 - 0.0006 19.5 0.0 0.0007 19.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region LapA_dom PF06305.11 AAAP01000520.1_1 - 3.2 7.6 6.9 0.64 9.9 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CPSase_sm_chain PF00988.22 AAAP01000522.1_1 - 5.5e-09 35.9 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OapA PF04225.12 AAAP01000523.1_1 - 4e-13 49.3 0.0 4.2e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Opacity-associated protein A LysM-like domain CTP_synth_N PF06418.14 AAAP01000524.1_1 - 4.4e-79 265.5 0.0 4.8e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus CbiA PF01656.23 AAAP01000524.1_1 - 0.0017 18.4 0.0 0.0019 18.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain TrbC PF04956.13 AAAP01000525.1_1 - 0.07 13.3 0.6 0.073 13.3 0.6 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family UvrD_C PF13361.6 AAAP01000526.1_1 - 5.9e-13 48.9 0.0 1.8e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AAAP01000526.1_1 - 9.6e-09 35.2 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Transgly PF00912.22 AAAP01000527.1_1 - 4.6e-59 198.9 0.0 5.9e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase tRNA-synt_1b PF00579.25 AAAP01000528.1_1 - 1.5e-40 139.3 0.0 1.7e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Glyco_transf_20 PF00982.21 AAAP01000529.1_1 - 6.7e-52 176.7 0.0 7.8e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Acetyltransf_3 PF13302.7 AAAP01000530.1_2 - 7.6e-28 97.9 0.3 9.5e-28 97.6 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01000530.1_2 - 8.8e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAAP01000530.1_2 - 1.7e-09 37.5 1.2 2.4e-09 37.0 1.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01000530.1_2 - 0.0015 18.9 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01000530.1_2 - 0.0028 17.6 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein sCache_3_3 PF17202.4 AAAP01000531.1_1 - 4.4e-27 94.6 0.0 6.1e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Single cache domain 3 Cache_3-Cache_2 PF17201.4 AAAP01000531.1_1 - 1.2e-13 51.1 0.0 1.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain sCache_3_2 PF17203.4 AAAP01000531.1_1 - 1.5e-06 28.3 0.2 2.9e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Single cache domain 3 dCache_3 PF14827.6 AAAP01000531.1_1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Double sensory domain of two-component sensor kinase CTP_transf_like PF01467.26 AAAP01000532.1_1 - 7.6e-08 32.7 0.0 9.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Inhibitor_I42 PF09394.10 AAAP01000533.1_2 - 0.0078 16.6 0.3 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 Chagasin family peptidase inhibitor I42 Trans_reg_C PF00486.28 AAAP01000534.1_1 - 6.9e-16 58.1 0.0 7.6e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_11 PF08279.12 AAAP01000534.1_1 - 0.13 12.2 0.2 5.1 7.1 0.0 2.2 2 1 0 2 2 2 0 HTH domain 2CSK_N PF08521.10 AAAP01000534.1_2 - 0.0023 18.0 0.1 0.0033 17.5 0.1 1.2 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal MTES_1575 PF18741.1 AAAP01000536.1_1 - 0.00081 19.5 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 PTSIIB_sorb PF03830.15 AAAP01000537.1_1 - 2e-22 80.0 0.8 2.2e-22 79.9 0.8 1.0 1 0 0 1 1 1 1 PTS system sorbose subfamily IIB component adh_short_C2 PF13561.6 AAAP01000538.1_1 - 5.4e-65 219.2 0.0 6.4e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01000538.1_1 - 5.6e-16 58.6 0.0 7.3e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01000538.1_1 - 0.025 14.5 0.0 0.049 13.5 0.0 1.5 2 0 0 2 2 2 0 KR domain OrfB_Zn_ribbon PF07282.11 AAAP01000539.1_1 - 5.1e-05 23.1 0.5 9.5e-05 22.2 0.5 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DZR PF12773.7 AAAP01000539.1_1 - 0.0021 18.0 4.0 0.0034 17.4 4.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 AAAP01000539.1_1 - 0.016 15.3 1.1 0.78 9.9 0.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 AAAP01000539.1_1 - 0.051 13.4 2.3 0.09 12.7 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 AAAP01000539.1_1 - 0.083 12.9 1.8 0.14 12.1 1.8 1.3 1 0 0 1 1 1 0 zinc-ribbons C1_2 PF03107.16 AAAP01000539.1_1 - 0.095 13.0 2.3 0.16 12.3 2.3 1.3 1 0 0 1 1 1 0 C1 domain OrfB_IS605 PF01385.19 AAAP01000539.1_1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Probable transposase zf_C2H2_13 PF18508.1 AAAP01000539.1_1 - 0.16 11.6 3.7 0.87 9.2 0.2 2.6 1 1 0 2 2 2 0 Zinc finger domain A2L_zn_ribbon PF08792.10 AAAP01000539.1_1 - 1.1 9.1 3.8 12 5.8 3.8 2.3 1 1 1 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS91 PF14319.6 AAAP01000539.1_1 - 1.5 8.9 7.4 12 6.1 0.6 2.9 2 1 1 3 3 3 0 Transposase zinc-binding domain Radical_SAM PF04055.21 AAAP01000540.1_1 - 1.5e-19 71.0 0.0 3.3e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAAP01000540.1_1 - 0.0091 16.1 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain MarR_2 PF12802.7 AAAP01000541.1_1 - 3.3e-13 49.3 3.7 3.3e-13 49.3 3.7 2.1 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 AAAP01000541.1_1 - 1.5e-10 41.4 0.5 3.2e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AAAP01000541.1_1 - 2.1e-07 30.7 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAAP01000541.1_1 - 1.9e-05 24.4 0.4 1.9e-05 24.4 0.4 2.2 3 0 0 3 3 3 1 IclR helix-turn-helix domain TrmB PF01978.19 AAAP01000541.1_1 - 0.0001 22.1 0.3 0.00018 21.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAAP01000541.1_1 - 0.00092 18.7 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAAP01000541.1_1 - 0.0023 17.9 0.5 0.0023 17.9 0.5 2.7 2 1 1 3 3 3 1 Helix-turn-helix domain HxlR PF01638.17 AAAP01000541.1_1 - 0.0042 16.9 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Replic_Relax PF13814.6 AAAP01000541.1_1 - 0.012 15.7 0.3 0.017 15.2 0.3 1.3 1 0 0 1 1 1 0 Replication-relaxation DUF2250 PF10007.9 AAAP01000541.1_1 - 0.055 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PadR PF03551.14 AAAP01000541.1_1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AAAP01000541.1_1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain CLP_protease PF00574.23 AAAP01000542.1_1 - 2e-72 242.9 0.0 2.4e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF3473 PF11959.8 AAAP01000542.1_1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) HMGL-like PF00682.19 AAAP01000543.1_1 - 0.00023 20.8 0.1 0.00024 20.7 0.1 1.1 1 0 0 1 1 1 1 HMGL-like DUF1471 PF07338.13 AAAP01000543.1_1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) MM_CoA_mutase PF01642.22 AAAP01000544.1_1 - 2.4e-17 62.7 0.0 2.5e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Autotransporter PF03797.19 AAAP01000546.1_1 - 4.6e-52 177.2 15.9 6.3e-52 176.8 15.9 1.2 1 0 0 1 1 1 1 Autotransporter beta-domain OMP_b-brl PF13505.6 AAAP01000546.1_1 - 0.00011 22.3 6.8 0.0002 21.6 1.1 2.2 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain Not3 PF04065.15 AAAP01000548.1_1 - 0.079 12.4 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component TPR_MLP1_2 PF07926.12 AAAP01000548.1_1 - 2.2 8.4 5.1 26 4.9 5.3 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein QueF PF14489.6 AAAP01000549.1_1 - 2.9e-29 101.0 0.0 3.8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein QueF_N PF14819.6 AAAP01000549.1_1 - 0.0017 18.7 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DIM PF08194.12 AAAP01000550.1_1 - 0.86 9.9 3.4 1.3 9.3 3.4 1.3 1 0 0 1 1 1 0 DIM protein Endonuclease_NS PF01223.23 AAAP01000551.1_3 - 1.3e-39 136.3 0.0 1.5e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 AAAP01000551.1_3 - 4.6e-05 23.5 0.0 8.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF839 PF05787.13 AAAP01000552.1_1 - 3.2e-61 208.1 0.0 3.7e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) Aminotran_5 PF00266.19 AAAP01000553.1_1 - 4.4e-33 114.8 0.0 5.1e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01000553.1_1 - 2e-08 33.9 0.0 2.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase STAS_2 PF13466.6 AAAP01000553.1_1 - 0.027 14.8 2.5 0.027 14.8 2.5 2.1 2 0 0 2 2 2 0 STAS domain SBP_bac_3 PF00497.20 AAAP01000555.1_1 - 9.4e-09 35.0 0.0 1.1e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_3 PF00497.20 AAAP01000555.1_2 - 5.5e-07 29.2 0.0 5.9e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Dioxygenase_C PF00775.21 AAAP01000557.1_1 - 0.14 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Dioxygenase FAD_binding_4 PF01565.23 AAAP01000558.1_1 - 1.4e-29 102.6 4.1 1.9e-29 102.2 4.1 1.1 1 0 0 1 1 1 1 FAD binding domain PrsW-protease PF13367.6 AAAP01000559.1_1 - 1.2e-36 126.0 11.3 2.1e-36 125.3 11.3 1.3 1 0 0 1 1 1 1 PrsW family intramembrane metalloprotease CcmD PF04995.14 AAAP01000559.1_1 - 0.0022 18.0 2.8 0.0022 18.0 2.8 4.4 4 0 0 4 4 4 1 Heme exporter protein D (CcmD) CPBP PF02517.16 AAAP01000559.1_1 - 0.16 12.4 9.7 0.065 13.6 5.7 2.4 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease SIR2_2 PF13289.6 AAAP01000560.1_1 - 6.1e-06 26.4 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 SIR2-like domain CbtB PF09489.10 AAAP01000561.1_1 - 0.12 12.5 0.3 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Transketolase_C PF02780.20 AAAP01000562.1_1 - 0.0076 16.1 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 AAAP01000563.1_1 - 1.3e-09 38.3 0.0 4e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAAP01000563.1_1 - 0.04 14.5 0.0 0.06 14.0 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Attacin_N PF03768.15 AAAP01000563.1_1 - 0.046 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Attacin, N-terminal region polyprenyl_synt PF00348.17 AAAP01000565.1_1 - 3.2e-30 105.0 0.0 4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Trans_reg_C PF00486.28 AAAP01000566.1_2 - 4.2e-21 74.8 0.4 2.3e-20 72.5 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01000566.1_2 - 1.3e-06 28.6 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain DUF3341 PF11821.8 AAAP01000567.1_1 - 5.4e-08 32.7 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) Rho_RNA_bind PF07497.12 AAAP01000568.1_1 - 4.2e-31 106.6 0.0 6.5e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain Rho_N PF07498.12 AAAP01000568.1_1 - 1.5e-09 37.7 0.1 2.3e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain ATP-synt_ab PF00006.25 AAAP01000568.1_1 - 6.6e-06 25.9 0.0 8.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain OB_RNB PF08206.11 AAAP01000568.1_1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_25 PF13481.6 AAAP01000568.1_1 - 0.0099 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TssC PF17541.2 AAAP01000568.1_1 - 0.099 11.5 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Trp_syntA PF00290.20 AAAP01000570.1_1 - 1.1e-23 83.4 1.0 1.3e-23 83.2 1.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 AAAP01000570.1_1 - 6.3e-05 22.5 0.1 7.1e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 AAAP01000570.1_1 - 0.0049 16.2 1.6 0.0059 15.9 1.6 1.1 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PcrB PF01884.17 AAAP01000570.1_1 - 0.006 16.1 0.2 0.0075 15.7 0.2 1.2 1 0 0 1 1 1 1 PcrB family Transketolase_C PF02780.20 AAAP01000571.1_1 - 0.22 11.4 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Transketolase, C-terminal domain Glyoxalase PF00903.25 AAAP01000571.1_2 - 3.2e-18 66.2 0.0 4.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAAP01000571.1_2 - 2.3e-11 43.9 0.0 1e-10 41.8 0.0 1.8 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01000571.1_2 - 1e-05 26.3 0.0 1.3e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AAAP01000571.1_2 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AAAP01000571.1_2 - 0.0099 16.0 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain SoxZ PF08770.11 AAAP01000572.1_1 - 3.2e-07 30.0 0.1 3.5e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ SoxY PF13501.6 AAAP01000572.1_2 - 1.4e-37 128.4 0.4 1.7e-37 128.0 0.4 1.1 1 0 0 1 1 1 1 Sulfur oxidation protein SoxY Desulfoferrodox PF01880.18 AAAP01000572.1_2 - 0.013 16.1 0.0 0.024 15.3 0.0 1.4 1 1 0 1 1 1 0 Desulfoferrodoxin PHY PF00360.20 AAAP01000573.1_1 - 1.6e-23 82.9 0.1 3.1e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 AAAP01000573.1_1 - 1.6e-18 67.2 0.0 2.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01000573.1_1 - 1.2e-14 54.1 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01000573.1_1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Exostosin PF03016.15 AAAP01000574.1_2 - 0.011 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Exostosin family Glyco_trans_1_2 PF13524.6 AAAP01000574.1_2 - 0.074 13.4 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Radical_SAM PF04055.21 AAAP01000575.1_1 - 0.00027 21.3 0.0 0.00033 21.1 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily Cyt_bd_oxida_II PF02322.15 AAAP01000576.1_2 - 8.6e-60 202.6 14.7 1e-59 202.4 14.7 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF4037 PF13228.6 AAAP01000578.1_1 - 2.1e-28 99.1 0.0 3.1e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) Acyl-CoA_dh_N PF02771.16 AAAP01000579.1_1 - 0.011 16.4 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01000579.1_1 - 0.039 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAAP01000579.1_2 - 4.4e-07 30.2 0.9 6.8e-07 29.6 0.6 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01000579.1_2 - 6.9e-05 23.1 2.9 0.00014 22.2 2.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1863 PF08937.11 AAAP01000580.1_1 - 1.1e-29 103.4 0.1 1.4e-29 103.0 0.1 1.1 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Peptidase_C39 PF03412.15 AAAP01000581.1_1 - 2.9e-35 121.0 0.0 3.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family ABC_membrane PF00664.23 AAAP01000581.1_1 - 6.1e-13 49.0 2.5 8.9e-13 48.5 2.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C70 PF12385.8 AAAP01000581.1_1 - 0.00058 19.9 0.0 0.0033 17.4 0.0 2.0 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 AAAP01000581.1_1 - 0.0075 16.8 0.0 0.055 14.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase_C39 like family Guanylate_cyc_2 PF09778.9 AAAP01000581.1_1 - 0.008 15.6 0.0 0.095 12.1 0.0 2.1 2 0 0 2 2 2 1 Guanylylate cyclase Porin_2 PF02530.14 AAAP01000582.1_1 - 3.7e-18 66.0 0.5 4.3e-18 65.8 0.5 1.1 1 0 0 1 1 1 1 Porin subfamily Exo_endo_phos PF03372.23 AAAP01000583.1_1 - 0.021 14.4 0.2 0.024 14.2 0.2 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 AAAP01000583.1_2 - 1.5e-09 37.7 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1697 PF08002.11 AAAP01000584.1_1 - 1.3e-18 67.8 0.0 1.4e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Amidase PF01425.21 AAAP01000584.1_2 - 8.1e-13 48.1 0.1 9.4e-13 47.9 0.1 1.0 1 0 0 1 1 1 1 Amidase GARS_A PF01071.19 AAAP01000585.1_1 - 8.3e-62 208.4 0.0 1e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 AAAP01000585.1_1 - 0.00027 21.0 0.0 0.00056 20.0 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Phage_tail_2 PF06199.11 AAAP01000586.1_1 - 1.9e-35 121.9 0.0 2.1e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein DUF3168 PF11367.8 AAAP01000586.1_2 - 0.00099 19.3 1.6 0.0011 19.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3168) Response_reg PF00072.24 AAAP01000588.1_1 - 6e-10 39.3 0.0 6.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAAP01000588.1_2 - 3.1e-05 23.9 0.0 7.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AAAP01000588.1_2 - 6.8e-05 23.3 0.0 0.00031 21.2 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 AAAP01000588.1_2 - 0.0011 19.4 5.7 0.0048 17.4 5.7 2.2 1 1 0 1 1 1 1 Histidine kinase DoxX_3 PF13781.6 AAAP01000588.1_2 - 0.22 12.2 5.9 0.41 11.3 5.9 1.4 1 0 0 1 1 1 0 DoxX-like family MarC PF01914.17 AAAP01000588.1_2 - 0.33 10.3 2.8 4.1 6.7 2.8 2.0 1 1 1 2 2 2 0 MarC family integral membrane protein TctB PF07331.11 AAAP01000588.1_2 - 1.7 8.9 6.5 2.7 8.3 6.5 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Glycos_transf_2 PF00535.26 AAAP01000589.1_1 - 5.5e-10 39.3 0.0 5.5e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01000589.1_1 - 2.3e-05 24.4 2.1 2.5e-05 24.3 2.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01000589.1_1 - 0.0015 19.0 0.0 0.0016 18.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 HAD PF12710.7 AAAP01000589.1_1 - 0.022 15.2 0.1 0.023 15.1 0.1 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01000589.1_1 - 0.029 14.4 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1449 PF07290.11 AAAP01000589.1_1 - 0.095 12.3 1.1 0.1 12.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF416 PF04222.12 AAAP01000589.1_1 - 0.18 11.2 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DUF456 PF04306.13 AAAP01000589.1_2 - 0.0032 17.8 1.9 0.0034 17.7 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF456) CwsA PF10814.8 AAAP01000589.1_3 - 0.017 15.3 0.7 0.023 14.9 0.7 1.1 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Alk_phosphatase PF00245.20 AAAP01000590.1_1 - 1.1e-43 149.8 0.2 1.4e-43 149.4 0.2 1.1 1 0 0 1 1 1 1 Alkaline phosphatase RF-1 PF00472.20 AAAP01000591.1_1 - 5.2e-25 87.6 0.1 6.7e-25 87.3 0.1 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 AAAP01000591.1_1 - 0.0051 17.2 0.0 0.0063 16.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein BolA PF01722.18 AAAP01000591.1_2 - 1.3e-26 92.7 0.1 1.4e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 BolA-like protein DUF1482 PF07358.11 AAAP01000592.1_1 - 0.099 12.6 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) Aminotran_3 PF00202.21 AAAP01000592.1_2 - 4.2e-83 279.3 0.0 5e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AAAP01000592.1_2 - 0.0002 20.7 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAAP01000592.1_2 - 0.024 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II CoA_transf_3 PF02515.17 AAAP01000593.1_1 - 6.2e-28 98.0 0.0 7.3e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III FhuF PF06276.12 AAAP01000594.1_1 - 2.1e-09 38.0 0.4 2.9e-09 37.5 0.4 1.1 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter TspO_MBR PF03073.15 AAAP01000595.1_1 - 6.2e-41 139.6 26.5 7e-41 139.4 26.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Cyt_bd_oxida_II PF02322.15 AAAP01000595.1_1 - 0.0032 16.9 17.7 0.004 16.6 17.7 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II zf-CHC2 PF01807.20 AAAP01000596.1_1 - 2e-30 104.5 0.0 2.5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_N PF08275.11 AAAP01000596.1_1 - 5.9e-05 23.1 0.0 9.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain Ketoacyl-synt_C PF02801.22 AAAP01000597.1_1 - 1.4e-29 102.5 0.1 1.9e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 AAAP01000597.1_1 - 0.0032 17.9 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension TetR_C_33 PF13305.6 AAAP01000598.1_1 - 6e-07 30.2 1.8 7.3e-07 29.9 1.8 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAAP01000598.1_1 - 0.02 15.1 6.9 0.056 13.7 5.7 1.9 1 1 1 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF4328 PF14219.6 AAAP01000598.1_2 - 4.1e-19 68.8 26.7 4.6e-19 68.6 26.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) CP_ATPgrasp_1 PF04174.13 AAAP01000599.1_1 - 5.3e-28 98.0 0.0 6.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 A circularly permuted ATPgrasp CP_ATPgrasp_2 PF14403.6 AAAP01000599.1_1 - 1.4e-26 93.4 0.0 1.6e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 AMP-binding_C PF13193.6 AAAP01000600.1_1 - 5.4e-10 40.1 9.3 5.4e-10 40.1 9.3 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AAAP01000600.1_1 - 0.0046 15.6 0.8 0.0084 14.7 0.3 1.6 2 0 0 2 2 2 1 AMP-binding enzyme UbiA PF01040.18 AAAP01000600.1_2 - 0.002 17.5 0.7 0.0023 17.3 0.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RskA PF10099.9 AAAP01000601.1_1 - 6.5e-28 98.2 28.1 2.8e-27 96.2 28.1 1.9 1 1 0 1 1 1 1 Anti-sigma-K factor rskA zf-HC2 PF13490.6 AAAP01000601.1_1 - 0.055 13.7 0.9 0.2 12.0 0.9 2.0 1 0 0 1 1 1 0 Putative zinc-finger RibD_C PF01872.17 AAAP01000601.1_2 - 0.0019 18.1 0.0 0.0021 17.9 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain CT_C_D PF02682.16 AAAP01000602.1_1 - 9.1e-44 149.6 0.6 1.2e-43 149.2 0.6 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D ADH_zinc_N PF00107.26 AAAP01000604.1_1 - 2e-18 66.6 0.0 2.7e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01000604.1_1 - 1.4e-17 65.0 0.1 1.7e-17 64.7 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase H_PPase PF03030.16 AAAP01000605.1_1 - 3.5e-70 237.4 0.0 5.8e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF1129 PF06570.11 AAAP01000605.1_1 - 0.32 10.4 1.7 0.65 9.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4231 PF14015.6 AAAP01000605.1_1 - 5.3 7.6 6.0 6.4 7.3 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ABC-3 PF00950.17 AAAP01000605.1_1 - 7.6 5.9 10.4 2.5 7.5 3.3 2.1 2 0 0 2 2 2 0 ABC 3 transport family HpcH_HpaI PF03328.14 AAAP01000606.1_1 - 5e-33 114.1 1.1 5.5e-33 114.0 1.1 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01000606.1_1 - 0.00037 19.8 0.0 0.00041 19.6 0.0 1.1 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold DUF2079 PF09852.9 AAAP01000606.1_1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Methyltr_RsmB-F PF01189.17 AAAP01000607.1_1 - 2.3e-41 141.6 0.0 3e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 AAAP01000607.1_1 - 7.6e-07 29.7 0.1 0.00014 22.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAAP01000607.1_1 - 1.8e-05 24.4 0.0 0.0077 15.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AAAP01000607.1_1 - 2.3e-05 24.2 0.0 4.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01000607.1_1 - 7.9e-05 22.1 0.0 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 AAAP01000607.1_1 - 0.0005 21.1 0.1 0.0057 17.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01000607.1_1 - 0.00088 19.9 0.0 0.0097 16.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAAP01000607.1_1 - 0.002 18.2 0.0 0.005 17.0 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N PF00107.26 AAAP01000607.1_1 - 0.011 15.7 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_15 PF09445.10 AAAP01000607.1_1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_5 PF01795.19 AAAP01000607.1_1 - 0.024 14.2 0.0 0.062 12.8 0.0 1.6 2 0 0 2 2 2 0 MraW methylase family Methyltransf_12 PF08242.12 AAAP01000607.1_1 - 0.037 14.8 0.1 12 6.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 AAAP01000607.1_1 - 0.049 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF5593 PF18007.1 AAAP01000607.1_1 - 0.11 13.2 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5593) Cons_hypoth95 PF03602.15 AAAP01000607.1_1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Response_reg PF00072.24 AAAP01000610.1_1 - 1.7e-14 53.9 0.0 2.3e-14 53.5 0.0 1.2 1 1 0 1 1 1 1 Response regulator receiver domain COX1 PF00115.20 AAAP01000611.1_1 - 2.6e-83 280.3 38.4 3.3e-83 279.9 38.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I UDG PF03167.19 AAAP01000612.1_2 - 9.5e-07 28.9 0.0 1e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Alkyl_sulf_dimr PF14863.6 AAAP01000613.1_1 - 0.058 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Bac_luciferase PF00296.20 AAAP01000616.1_1 - 1.2e-20 74.2 0.2 1.3e-20 74.1 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase YceD PF02620.17 AAAP01000618.1_1 - 0.00011 22.3 0.2 0.00019 21.5 0.2 1.3 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Ubiq_cyt_C_chap PF03981.12 AAAP01000618.1_2 - 2.2e-20 73.2 0.4 2.5e-20 73.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone NIR_SIR PF01077.22 AAAP01000619.1_1 - 4.5e-22 78.3 0.3 2.8e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01000619.1_1 - 7.6e-19 67.3 0.0 1.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain ABC_tran PF00005.27 AAAP01000621.1_1 - 2.2e-07 31.5 0.0 2.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01000621.1_1 - 0.00038 20.1 0.3 0.00065 19.4 0.1 1.5 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01000621.1_1 - 0.0045 17.3 0.1 0.0062 16.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01000621.1_1 - 0.0086 16.5 0.2 0.011 16.2 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01000621.1_1 - 0.019 14.8 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 AAAP01000621.1_1 - 0.025 14.2 0.5 0.049 13.2 0.1 1.6 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01000621.1_1 - 0.026 14.4 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AAAP01000621.1_1 - 0.028 14.6 0.2 0.038 14.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01000621.1_1 - 0.044 13.5 0.1 0.056 13.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01000621.1_1 - 0.072 13.6 0.0 0.074 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01000621.1_1 - 0.073 13.0 0.1 0.085 12.8 0.1 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 AAAP01000621.1_1 - 0.087 12.0 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 AAAP01000621.1_1 - 0.094 13.0 0.2 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01000621.1_1 - 0.096 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 AAAP01000621.1_1 - 0.15 11.0 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NACHT PF05729.12 AAAP01000621.1_1 - 0.2 11.6 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 AAAP01000621.1_1 - 0.23 12.0 0.2 0.36 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain HemolysinCabind PF00353.19 AAAP01000622.1_1 - 3.3e-05 23.8 23.1 1.7 8.7 0.3 6.4 6 0 0 6 6 6 6 RTX calcium-binding nonapeptide repeat (4 copies) AFP_2 PF18815.1 AAAP01000622.1_1 - 0.12 12.7 8.3 4.4 7.6 0.1 4.8 5 0 0 5 5 5 0 Bacterial antifreeze protein repeat ClpB_D2-small PF10431.9 AAAP01000623.1_1 - 0.00029 20.8 0.1 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.14 AAAP01000623.1_2 - 2.1e-10 41.0 0.0 2.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AMP-binding PF00501.28 AAAP01000625.1_1 - 1e-42 146.2 0.0 1.2e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1266 PF06889.11 AAAP01000626.1_1 - 3.5e-14 53.3 0.1 4.8e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1266) Glyco_hydro_39 PF01229.17 AAAP01000628.1_1 - 0.0023 16.6 0.3 0.0028 16.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Aminotran_5 PF00266.19 AAAP01000629.1_1 - 1.1e-89 301.0 0.1 1.4e-89 300.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAAP01000629.1_1 - 1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAAP01000629.1_1 - 1.2e-06 28.1 0.4 1.7e-06 27.6 0.4 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAAP01000629.1_1 - 3.1e-05 23.4 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AAAP01000629.1_1 - 7.6e-05 21.4 0.0 0.00011 20.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 AAAP01000629.1_1 - 0.054 12.2 0.1 0.16 10.6 0.1 1.7 1 1 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SelA PF03841.13 AAAP01000629.1_1 - 0.058 12.4 0.0 0.13 11.2 0.0 1.6 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase CobN-Mg_chel PF02514.16 AAAP01000630.1_1 - 5.7e-15 54.2 0.0 6.6e-15 54.0 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Fer4_NifH PF00142.18 AAAP01000630.1_2 - 5e-49 167.2 0.4 6.4e-49 166.8 0.4 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 AAAP01000630.1_2 - 3.7e-10 40.0 0.0 5.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01000630.1_2 - 3.2e-09 36.9 0.0 3.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAAP01000630.1_2 - 1.1e-08 34.7 0.0 1.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 AAAP01000630.1_2 - 1.8e-05 24.3 0.2 2.6e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 AAAP01000630.1_2 - 0.00029 20.6 0.0 0.00044 20.0 0.0 1.5 1 1 1 2 2 2 1 AAA domain MipZ PF09140.11 AAAP01000630.1_2 - 0.00094 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 AAAP01000630.1_2 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AAAP01000630.1_2 - 0.017 15.5 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 AAAP01000630.1_2 - 0.03 13.2 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.6 AAAP01000630.1_2 - 0.037 13.6 1.2 0.054 13.1 0.1 1.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 AAAP01000630.1_2 - 0.049 13.3 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 AAAP01000630.1_2 - 0.053 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 AAAP01000630.1_2 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 AAAP01000630.1_2 - 0.2 12.1 0.1 0.35 11.3 0.1 1.6 1 1 0 1 1 1 0 RNA helicase ParE_toxin PF05016.15 AAAP01000631.1_1 - 0.18 12.4 1.0 1.6 9.4 0.1 2.3 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE GAF PF01590.26 AAAP01000633.1_1 - 6.9e-13 49.4 0.2 9.2e-13 49.0 0.2 1.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAAP01000633.1_1 - 2.2e-10 41.0 0.4 3e-10 40.5 0.4 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAAP01000633.1_1 - 0.0041 17.5 0.0 0.0056 17.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain Sigma70_r2 PF04542.14 AAAP01000633.1_2 - 8.1e-10 38.3 5.2 1.4e-09 37.6 5.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 FTZ PF03867.14 AAAP01000633.1_2 - 0.11 12.0 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Na_H_Exchanger PF00999.21 AAAP01000634.1_1 - 1.1e-25 90.3 11.9 1.2e-25 90.1 11.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4271 PF14093.6 AAAP01000634.1_1 - 0.18 11.7 3.9 0.52 10.2 3.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Cyt_bd_oxida_II PF02322.15 AAAP01000634.1_1 - 1.1 8.5 16.9 1.8 7.9 15.5 1.8 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Lysine_decarbox PF03641.14 AAAP01000635.1_1 - 1.6e-22 80.0 0.1 2.6e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAAP01000635.1_1 - 2.9e-19 69.2 0.0 3.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AAAP01000635.1_1 - 0.0028 16.9 0.1 0.0043 16.3 0.1 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A ERG2_Sigma1R PF04622.12 AAAP01000635.1_1 - 0.0067 15.8 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein STALD PF18185.1 AAAP01000635.1_1 - 0.094 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family PHO4 PF01384.20 AAAP01000637.1_1 - 9e-29 100.6 6.1 1.1e-28 100.3 6.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Methyltransf_21 PF05050.12 AAAP01000638.1_1 - 2.6e-09 37.4 0.0 3.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain SfsA PF03749.13 AAAP01000638.1_2 - 1.1e-34 119.4 0.0 1.2e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain DUF21 PF01595.20 AAAP01000640.1_1 - 0.14 11.8 3.6 0.19 11.4 3.6 1.1 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain SLATT_3 PF18184.1 AAAP01000640.1_1 - 0.53 10.4 7.7 0.14 12.3 4.2 1.7 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 GspL_C PF12693.7 AAAP01000640.1_1 - 0.64 9.8 5.2 0.24 11.2 2.3 1.7 1 1 1 2 2 2 0 GspL periplasmic domain FtsX PF02687.21 AAAP01000640.1_1 - 2.1 8.9 12.1 1.5e+02 2.9 12.1 2.9 1 1 0 1 1 1 0 FtsX-like permease family ABC_export PF16962.5 AAAP01000640.1_1 - 4 5.8 7.1 4.6 5.6 7.1 1.0 1 0 0 1 1 1 0 Putative ABC exporter TPR_7 PF13176.6 AAAP01000640.1_2 - 0.0054 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01000640.1_2 - 0.012 16.4 5.6 0.024 15.5 4.5 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat PALP PF00291.25 AAAP01000641.1_1 - 2.5e-40 138.7 0.2 2.8e-40 138.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Resolvase PF00239.21 AAAP01000642.1_1 - 2.2e-12 47.3 0.1 3.2e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 Resolvase, N terminal domain MipZ PF09140.11 AAAP01000643.1_1 - 9.2e-13 48.1 0.1 1.3e-08 34.5 0.0 2.0 1 1 1 2 2 2 2 ATPase MipZ AAA_31 PF13614.6 AAAP01000643.1_1 - 4.1e-12 46.4 1.2 1.1e-09 38.5 0.1 2.0 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 AAAP01000643.1_1 - 3.4e-09 36.8 0.0 3.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAAP01000643.1_1 - 7.5e-07 28.6 0.7 6.7e-06 25.5 0.1 1.9 1 1 1 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AAAP01000643.1_1 - 1.5e-06 27.7 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 VirC1 protein ParA PF10609.9 AAAP01000643.1_1 - 4.2e-06 26.4 0.4 1.3e-05 24.8 0.1 1.7 1 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase ATP_bind_1 PF03029.17 AAAP01000643.1_1 - 2e-05 24.5 0.0 0.00065 19.6 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Methyltransf_24 PF13578.6 AAAP01000643.1_1 - 0.00047 21.1 0.1 0.00061 20.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain SRP54 PF00448.22 AAAP01000643.1_1 - 0.00067 19.3 0.1 0.0015 18.2 0.1 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 AAAP01000643.1_1 - 0.00094 19.5 0.0 0.0012 19.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 AAAP01000643.1_1 - 0.0024 17.4 0.1 0.028 13.9 0.1 1.9 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 AAAP01000643.1_1 - 0.0038 16.3 0.1 0.026 13.5 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 AAAP01000643.1_1 - 0.0056 16.2 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CLP1_P PF16575.5 AAAP01000643.1_1 - 0.0074 16.1 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 AAAP01000643.1_1 - 0.023 14.8 0.0 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 AAAP01000643.1_1 - 0.055 13.2 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 AAAP01000643.1_1 - 0.074 12.6 1.6 0.16 11.5 1.6 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 AAAP01000643.1_1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 AAAP01000643.1_1 - 0.12 12.0 0.1 0.46 10.1 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Fer4_NifH PF00142.18 AAAP01000643.1_1 - 0.12 11.8 0.3 0.3 10.5 0.1 1.6 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TonB_dep_Rec PF00593.24 AAAP01000645.1_1 - 6.6e-37 128.5 7.7 8.2e-37 128.2 7.7 1.0 1 0 0 1 1 1 1 TonB dependent receptor GAS PF13851.6 AAAP01000646.1_1 - 0.014 14.8 0.0 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 AAAP01000646.1_1 - 0.062 14.4 0.1 0.069 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein SOGA HisKA PF00512.25 AAAP01000646.1_1 - 0.07 13.2 0.3 0.081 13.0 0.3 1.1 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HOOK PF05622.12 AAAP01000646.1_1 - 0.082 11.0 0.0 0.082 11.0 0.0 1.0 1 0 0 1 1 1 0 HOOK protein GCD14 PF08704.10 AAAP01000646.1_2 - 6.2e-05 22.8 0.0 0.0047 16.6 0.0 2.1 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit DctM PF06808.12 AAAP01000646.1_2 - 0.079 11.8 0.0 0.098 11.5 0.0 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component FAD_binding_4 PF01565.23 AAAP01000647.1_1 - 8.7e-27 93.6 4.1 1.1e-26 93.2 4.1 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 AAAP01000647.1_1 - 3.4e-09 36.9 0.0 4.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase TraD PF06412.11 AAAP01000647.1_1 - 0.18 11.6 2.3 2.1 8.2 0.3 2.6 2 1 0 2 2 2 0 Conjugal transfer protein TraD Glyco_hydro_15 PF00723.21 AAAP01000648.1_1 - 0.0012 17.8 0.0 0.0012 17.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 PreAtp-grasp PF18604.1 AAAP01000649.1_1 - 0.058 13.0 0.4 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Pre ATP-grasp domain Lactamase_B PF00753.27 AAAP01000650.1_1 - 5.3e-11 42.9 0.2 6.5e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01000650.1_1 - 0.00012 21.6 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AAAP01000650.1_1 - 0.19 11.1 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain MFS_1 PF07690.16 AAAP01000651.1_1 - 5.4e-06 25.6 19.8 6.1e-06 25.4 19.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily NIR_SIR_ferr PF03460.17 AAAP01000652.1_1 - 0.041 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF4235 PF14019.6 AAAP01000653.1_1 - 6.4e-17 61.4 10.2 7.2e-17 61.2 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) SfLAP PF11139.8 AAAP01000653.1_1 - 0.038 13.4 3.3 0.042 13.3 3.3 1.0 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF3918 PF13056.6 AAAP01000653.1_1 - 0.096 12.3 2.3 1.5 8.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) FtsX PF02687.21 AAAP01000653.1_2 - 9.2e-14 51.7 11.5 1.9e-13 50.7 5.0 2.1 2 0 0 2 2 2 2 FtsX-like permease family LptF_LptG PF03739.14 AAAP01000653.1_2 - 0.78 8.5 5.6 1.2 8.0 5.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HTH_1 PF00126.27 AAAP01000654.1_2 - 1.6e-17 63.2 1.0 3.4e-17 62.1 1.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HlyD_D23 PF16576.5 AAAP01000655.1_1 - 2.5e-05 23.6 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion T2SSE_N PF05157.15 AAAP01000656.1_1 - 0.15 12.3 0.4 0.24 11.7 0.1 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain Oberon_cc PF16312.5 AAAP01000657.1_2 - 0.012 15.5 0.1 0.014 15.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of Oberon malic PF00390.19 AAAP01000658.1_1 - 1.6e-14 54.1 0.5 1.2e-13 51.3 0.1 2.3 2 1 0 2 2 2 1 Malic enzyme, N-terminal domain ACT_4 PF13291.6 AAAP01000658.1_1 - 3e-05 24.5 0.1 0.00012 22.5 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 AAAP01000658.1_1 - 0.0022 17.7 0.4 0.0041 16.8 0.4 1.5 1 0 0 1 1 1 1 ACT domain FeS_assembly_P PF01883.19 AAAP01000658.1_1 - 0.044 14.0 0.7 0.095 12.9 0.7 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein DUF779 PF05610.11 AAAP01000659.1_1 - 6.6e-08 32.7 0.0 9.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF779) BPD_transp_1 PF00528.22 AAAP01000660.1_1 - 1.9e-14 53.8 19.0 1.9e-14 53.8 19.0 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DEC-1_N PF04625.13 AAAP01000661.1_1 - 0.35 9.8 7.1 0.52 9.3 7.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ILVD_EDD PF00920.21 AAAP01000661.1_2 - 4e-21 75.2 0.2 4.5e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family DUF11 PF01345.18 AAAP01000662.1_1 - 1.3e-08 35.0 8.4 7e-06 26.3 0.6 3.6 3 0 0 3 3 3 2 Domain of unknown function DUF11 NPCBM_assoc PF10633.9 AAAP01000662.1_1 - 1.2e-05 25.5 14.4 0.0039 17.4 2.4 5.0 3 2 1 4 4 4 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF756 PF05506.12 AAAP01000662.1_1 - 0.06 14.3 3.8 3.5 8.6 0.5 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF756) CARDB PF07705.11 AAAP01000662.1_1 - 0.069 13.4 0.1 1.8 8.9 0.0 2.8 2 1 0 2 2 2 0 CARDB Radical_SAM PF04055.21 AAAP01000663.1_1 - 0.052 13.9 1.1 0.055 13.8 1.1 1.1 1 0 0 1 1 1 0 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01000663.1_1 - 0.14 12.5 0.4 0.15 12.4 0.4 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain CBM_48 PF02922.18 AAAP01000664.1_1 - 1.5e-18 66.9 0.0 2.7e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 AAAP01000664.1_1 - 5e-07 29.6 0.0 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Response_reg PF00072.24 AAAP01000666.1_2 - 3.8e-24 85.0 0.0 5.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01000666.1_2 - 9.2e-16 57.1 0.0 1.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01000666.1_2 - 9.9e-08 31.6 0.7 1.8e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01000666.1_2 - 0.002 17.6 0.1 0.0046 16.5 0.1 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AAAP01000666.1_2 - 0.0099 15.4 0.0 0.032 13.8 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AAAP01000666.1_2 - 0.013 15.4 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 ECF sigma factor HTH_23 PF13384.6 AAAP01000666.1_2 - 0.085 12.7 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAAP01000666.1_2 - 0.19 11.6 0.1 0.19 11.6 0.1 3.0 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain HTH_42 PF06224.12 AAAP01000667.1_1 - 4.1e-30 105.4 7.5 5.6e-30 105.0 7.5 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain PAS_7 PF12860.7 AAAP01000669.1_1 - 1.8e-14 53.8 0.0 2.3e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01000669.1_1 - 2.4e-05 24.6 1.0 0.00016 21.9 0.1 2.1 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAAP01000669.1_1 - 0.029 14.4 0.9 0.084 12.9 0.0 2.2 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01000669.1_1 - 0.035 14.1 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF21 PF01595.20 AAAP01000670.1_1 - 5.4e-30 104.4 7.3 6.8e-30 104.1 7.3 1.0 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain SLATT_5 PF18160.1 AAAP01000670.1_1 - 0.21 10.9 0.1 0.21 10.9 0.1 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MFS_1 PF07690.16 AAAP01000670.1_1 - 0.5 9.2 12.8 1.1 8.1 12.8 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF1345 PF07077.11 AAAP01000672.1_1 - 0.036 13.8 0.4 0.045 13.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) LPG_synthase_TM PF03706.13 AAAP01000673.1_1 - 5.8e-23 81.9 26.0 7.3e-23 81.5 26.0 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF3339 PF11820.8 AAAP01000673.1_1 - 0.047 13.9 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3339) SseC PF04888.12 AAAP01000673.1_1 - 0.63 9.6 6.5 1.1 8.8 6.5 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DHquinase_II PF01220.19 AAAP01000675.1_1 - 0.00015 21.4 0.3 0.00017 21.3 0.3 1.1 1 0 0 1 1 1 1 Dehydroquinase class II PQQ PF01011.21 AAAP01000675.1_1 - 0.061 13.3 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 PQQ enzyme repeat TPR_21 PF09976.9 AAAP01000676.1_1 - 0.00013 21.7 4.3 0.00026 20.8 4.3 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 AAAP01000676.1_1 - 0.00016 21.6 0.0 9.6 6.7 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01000676.1_1 - 0.00048 20.0 8.7 0.23 11.7 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01000676.1_1 - 0.0026 18.2 37.3 0.14 12.8 5.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01000676.1_1 - 0.008 16.7 9.3 2.5 8.7 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01000676.1_1 - 0.014 15.2 0.2 0.49 10.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01000676.1_1 - 0.016 15.2 6.4 1.7 8.8 0.0 4.2 4 2 1 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 AAAP01000676.1_1 - 0.094 13.4 2.0 20 6.0 0.2 3.0 3 0 0 3 3 2 0 Sel1 repeat Cytidylate_kin PF02224.18 AAAP01000676.1_1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.7 1 1 1 2 2 2 0 Cytidylate kinase TPR_14 PF13428.6 AAAP01000676.1_1 - 0.51 11.3 20.3 9.6 7.3 1.9 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01000676.1_1 - 4.8 7.2 11.3 40 4.2 0.9 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat GDP_Man_Dehyd PF16363.5 AAAP01000677.1_1 - 2.8e-07 30.3 0.0 2.3e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase CP_ATPgrasp_1 PF04174.13 AAAP01000677.1_1 - 0.036 13.1 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Med13_N PF11597.8 AAAP01000677.1_1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Peripla_BP_1 PF00532.21 AAAP01000679.1_1 - 4e-12 46.1 0.2 6.9e-12 45.4 0.2 1.3 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAAP01000679.1_1 - 1.3e-10 41.9 0.2 1.7e-09 38.2 0.0 2.2 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AAAP01000679.1_1 - 1.9e-09 37.5 0.0 2.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Pro_isomerase PF00160.21 AAAP01000679.1_1 - 0.2 11.9 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trans_reg_C PF00486.28 AAAP01000680.1_1 - 6.6e-16 58.2 0.0 1.8e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01000680.1_1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain PspA_IM30 PF04012.12 AAAP01000681.1_1 - 0.016 14.8 1.7 0.018 14.6 1.7 1.1 1 0 0 1 1 1 0 PspA/IM30 family URO-D PF01208.17 AAAP01000682.1_1 - 8.4e-59 199.5 0.0 9.8e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3253 PF11625.8 AAAP01000682.1_1 - 0.23 11.7 1.0 7.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) DegV PF02645.16 AAAP01000683.1_1 - 0.013 14.9 0.6 0.013 14.8 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 Epimerase PF01370.21 AAAP01000684.1_1 - 4.5e-14 52.5 0.0 4.8e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01000684.1_1 - 4.8e-09 35.7 0.0 6.2e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01000684.1_1 - 2.1e-08 33.5 0.0 2.3e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AAAP01000684.1_1 - 2.8e-08 33.5 0.0 3.1e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAAP01000684.1_1 - 5.7e-05 22.4 0.0 9.2e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 AAAP01000684.1_1 - 0.00031 20.7 0.0 0.00081 19.3 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01000684.1_1 - 0.00051 20.0 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AAAP01000684.1_1 - 0.022 15.0 0.0 0.034 14.4 0.0 1.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 AAAP01000684.1_1 - 0.037 14.1 0.2 0.046 13.8 0.2 1.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 AAAP01000684.1_1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase OCD_Mu_crystall PF02423.15 AAAP01000685.1_1 - 1e-09 37.8 0.0 1.4e-09 37.3 0.0 1.2 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PGI PF00342.19 AAAP01000687.1_1 - 6e-28 97.7 0.1 7.3e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DLH PF01738.18 AAAP01000687.1_2 - 6.6e-07 29.1 0.0 2.4e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Acetyltransf_1 PF00583.25 AAAP01000688.1_2 - 1e-09 38.6 0.1 1.2e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01000688.1_2 - 6.2e-06 26.5 0.0 7.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01000688.1_2 - 9.5e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AAAP01000688.1_2 - 7.3e-05 22.7 0.0 8.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01000688.1_2 - 0.00024 21.2 0.1 0.00036 20.6 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AAAP01000688.1_2 - 0.00066 19.9 0.0 0.00072 19.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01000688.1_2 - 0.0011 19.6 0.1 0.0015 19.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_34 PF13872.6 AAAP01000688.1_2 - 0.019 13.9 0.0 0.02 13.8 0.0 1.0 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Acetyltransf_8 PF13523.6 AAAP01000688.1_2 - 0.058 13.1 0.1 0.082 12.6 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PGM_PMM_I PF02878.16 AAAP01000688.1_2 - 0.15 11.8 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Pyridox_ox_2 PF12900.7 AAAP01000688.1_3 - 9.7e-26 90.4 1.3 1.2e-25 90.2 1.3 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Phage_integrase PF00589.22 AAAP01000689.1_1 - 1.2e-10 41.5 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 AAAP01000689.1_1 - 0.00025 21.4 0.2 0.00065 20.0 0.2 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 AAAP01000689.1_1 - 0.01 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 AAAP01000689.1_1 - 0.13 12.6 0.5 0.25 11.6 0.5 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PDT PF00800.18 AAAP01000690.1_2 - 1.6e-34 119.4 0.0 1.9e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Aminotran_1_2 PF00155.21 AAAP01000692.1_1 - 4.2e-27 95.3 0.1 4.7e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_18 PF12833.7 AAAP01000693.1_1 - 2.9e-14 53.1 1.4 3.9e-14 52.7 1.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01000693.1_1 - 8.9e-09 35.2 0.0 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_7 PF02796.15 AAAP01000693.1_1 - 0.0033 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase TetR_N PF00440.23 AAAP01000693.1_1 - 0.0035 17.1 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 AAAP01000693.1_1 - 0.009 15.8 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 AAAP01000693.1_1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_22 PF13309.6 AAAP01000693.1_1 - 0.019 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_Tnp_1_2 PF13022.6 AAAP01000693.1_1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_6 PF01418.17 AAAP01000693.1_1 - 0.092 12.7 0.1 0.77 9.8 0.0 2.3 2 1 1 3 3 3 0 Helix-turn-helix domain, rpiR family HTH_Tnp_1 PF01527.20 AAAP01000693.1_1 - 0.1 12.9 0.3 0.36 11.2 0.0 2.0 2 1 0 2 2 2 0 Transposase Catalase PF00199.19 AAAP01000694.1_1 - 1.1e-64 219.0 0.0 1.3e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AAAP01000694.1_1 - 3.2e-19 68.9 0.1 1e-18 67.3 0.1 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Arginase PF00491.21 AAAP01000695.1_1 - 6.6e-36 124.3 0.4 1.8e-35 122.8 0.4 1.6 1 1 0 1 1 1 1 Arginase family NBD_C PF17042.5 AAAP01000695.1_1 - 0.021 15.4 0.2 0.052 14.0 0.2 1.6 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain GDPD PF03009.17 AAAP01000696.1_1 - 6.8e-24 85.0 0.0 1e-23 84.4 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DHquinase_II PF01220.19 AAAP01000696.1_2 - 5.9e-18 64.9 0.0 6.9e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Dehydroquinase class II DUF4996 PF16387.5 AAAP01000696.1_2 - 0.05 14.1 0.0 0.067 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function TEX13 PF15186.6 AAAP01000696.1_2 - 0.095 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DNA_gyraseB PF00204.25 AAAP01000697.1_1 - 1.5e-37 128.7 0.0 2.3e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 AAAP01000697.1_1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OTCace_N PF02729.21 AAAP01000699.1_1 - 0.0047 16.9 0.0 0.0049 16.9 0.0 1.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Pribosyltran PF00156.27 AAAP01000699.1_2 - 6.2e-20 71.3 0.3 8.4e-20 70.9 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AAAP01000699.1_2 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 AAAP01000699.1_2 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TPP_enzyme_C PF02775.21 AAAP01000700.1_1 - 9.7e-25 87.1 0.1 1.5e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain tRNA_synt_1c_R1 PF04558.15 AAAP01000700.1_1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 TerB_C PF15615.6 AAAP01000701.1_1 - 3.7e-11 43.5 0.0 8.2e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 TerB-C domain TerB PF05099.13 AAAP01000701.1_1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TerB PEP-utilizers_C PF02896.18 AAAP01000702.1_1 - 3.2e-55 187.3 0.0 3.6e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain HlyIII PF03006.20 AAAP01000703.1_1 - 1.1e-10 41.6 2.0 1.2e-10 41.5 2.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related LssY_C PF14067.6 AAAP01000703.1_1 - 0.044 13.3 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 LssY C-terminus UCR_Fe-S_N PF10399.9 AAAP01000703.1_1 - 0.071 12.5 0.5 0.071 12.5 0.5 3.2 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF92 PF01940.16 AAAP01000703.1_1 - 0.86 9.0 5.9 0.94 8.8 5.9 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF92 DUF5337 PF17272.2 AAAP01000703.1_1 - 1.4 8.8 5.9 0.28 11.1 2.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Reductase_C PF14759.6 AAAP01000704.1_2 - 5.6e-12 46.1 0.0 1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Reductase C-terminal HD_assoc PF13286.6 AAAP01000705.1_1 - 9.1e-10 38.9 1.3 1.6e-08 35.0 1.1 2.6 1 1 1 2 2 2 1 Phosphohydrolase-associated domain DUF898 PF05987.13 AAAP01000706.1_1 - 6.8e-48 163.5 16.2 7.7e-48 163.3 16.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF4234 PF14018.6 AAAP01000706.1_1 - 0.34 11.1 8.6 1.9 8.6 8.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Ketoacyl-synt_C PF02801.22 AAAP01000708.1_1 - 1.2e-28 99.5 0.2 1.8e-28 99.0 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01000708.1_1 - 1.3e-09 38.1 0.2 5e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain CMD PF02627.20 AAAP01000708.1_1 - 0.2 11.7 2.0 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family BTAD PF03704.17 AAAP01000709.1_1 - 5.1e-34 117.8 17.9 5.1e-34 117.8 17.9 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 AAAP01000709.1_1 - 3.2e-07 30.3 0.0 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal ANAPC3 PF12895.7 AAAP01000709.1_1 - 0.0053 17.0 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AAAP01000709.1_1 - 0.0059 17.1 2.3 0.0059 17.1 2.3 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01000709.1_1 - 0.085 13.0 2.5 0.41 10.9 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_2 PF07724.14 AAAP01000710.1_1 - 8.4e-34 117.1 0.1 2.1e-33 115.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 AAAP01000710.1_1 - 8.2e-18 64.3 0.6 1.4e-17 63.5 0.6 1.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AAAP01000710.1_1 - 0.0003 21.2 0.0 0.0008 19.8 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NAPRTase_N PF17767.1 AAAP01000711.1_1 - 7.3e-12 45.8 0.0 1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Acetyltransf_10 PF13673.7 AAAP01000712.1_1 - 9.7e-07 28.8 0.0 1.2e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01000712.1_1 - 4.8e-06 26.8 0.0 5.5e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AAAP01000712.1_1 - 0.00011 22.3 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01000712.1_1 - 0.0085 16.5 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01000712.1_1 - 0.051 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Pribosyltran PF00156.27 AAAP01000712.1_2 - 3.8e-07 29.8 0.0 6.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EamA PF00892.20 AAAP01000714.1_1 - 2.4e-21 76.3 15.8 2.7e-21 76.2 15.8 1.0 1 0 0 1 1 1 1 EamA-like transporter family SLC35F PF06027.12 AAAP01000714.1_1 - 0.12 11.8 1.5 2.1 7.8 0.2 2.1 1 1 0 2 2 2 0 Solute carrier family 35 DUF1614 PF07758.11 AAAP01000714.1_1 - 0.58 10.1 6.5 0.13 12.3 2.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) HemolysinCabind PF00353.19 AAAP01000715.1_1 - 1e-09 38.2 28.4 5.4e-05 23.1 11.9 3.3 3 0 0 3 3 3 2 RTX calcium-binding nonapeptide repeat (4 copies) FAD_binding_4 PF01565.23 AAAP01000716.1_1 - 2.7e-13 49.8 0.4 1.1e-12 47.9 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain MFS_1 PF07690.16 AAAP01000717.1_1 - 3.8e-12 45.8 6.0 3.9e-12 45.8 6.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 AAAP01000717.1_1 - 0.00059 19.0 0.4 0.00063 18.9 0.4 1.1 1 0 0 1 1 1 1 PUCC protein Glyoxalase PF00903.25 AAAP01000718.1_1 - 7.7e-15 55.2 0.0 1.3e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01000718.1_1 - 0.02 15.7 0.0 0.057 14.2 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain DUF4810 PF16068.5 AAAP01000719.1_1 - 0.12 13.0 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) MFS_1 PF07690.16 AAAP01000719.1_2 - 1.7e-12 47.0 12.5 2.1e-12 46.7 12.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAAP01000719.1_2 - 0.0017 17.0 5.5 0.0021 16.7 5.5 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein LacY_symp PF01306.19 AAAP01000719.1_2 - 0.0025 16.6 0.2 0.0031 16.4 0.2 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 AAAP01000719.1_2 - 0.0025 16.3 9.0 0.003 16.0 9.0 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 AAAP01000719.1_2 - 0.17 10.7 4.9 0.21 10.4 4.9 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter DAP_epimerase PF01678.19 AAAP01000719.1_3 - 0.011 15.9 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase AP_endonuc_2 PF01261.24 AAAP01000720.1_2 - 4.1e-19 68.9 0.0 7.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UxuA PF03786.13 AAAP01000720.1_2 - 0.006 15.5 0.0 0.0084 15.0 0.0 1.1 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) PLDc PF00614.22 AAAP01000721.1_1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 AAAP01000721.1_1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain DNA_gyraseB PF00204.25 AAAP01000722.1_1 - 2.4e-56 189.9 0.3 2.9e-56 189.7 0.3 1.1 1 0 0 1 1 1 1 DNA gyrase B Methyltransf_24 PF13578.6 AAAP01000724.1_1 - 1.5e-06 29.1 0.1 5.8e-06 27.3 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain PSK_trans_fac PF07704.11 AAAP01000725.1_4 - 0.0051 17.5 0.6 0.0058 17.4 0.6 1.2 1 0 0 1 1 1 1 Rv0623-like transcription factor SepF PF04472.12 AAAP01000726.1_1 - 9.1e-26 89.9 0.0 1.3e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Cell division protein SepF MacB_PCD PF12704.7 AAAP01000727.1_1 - 5.1e-11 43.3 0.4 5.1e-11 43.3 0.4 2.1 1 1 1 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AAAP01000727.1_1 - 8.6e-08 32.6 2.9 8.6e-08 32.6 2.9 2.1 2 0 0 2 2 2 1 FtsX-like permease family SBP_bac_5 PF00496.22 AAAP01000728.1_1 - 6.8e-27 94.4 0.0 8.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Haem_degrading PF03928.14 AAAP01000728.1_2 - 1.9e-20 73.1 0.1 2.1e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 Haem-degrading Acyl_transf_1 PF00698.21 AAAP01000729.1_1 - 2.5e-19 69.9 0.1 7.4e-19 68.4 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 AAAP01000729.1_1 - 1.1e-17 64.5 0.0 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension CobN-Mg_chel PF02514.16 AAAP01000730.1_1 - 3.2e-105 353.1 0.0 6.4e-63 213.0 0.0 2.0 1 1 1 2 2 2 2 CobN/Magnesium Chelatase DUF5133 PF17196.4 AAAP01000730.1_1 - 0.03 14.5 0.3 0.55 10.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) Epimerase PF01370.21 AAAP01000731.1_2 - 7e-21 74.8 0.0 8.6e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01000731.1_2 - 3.1e-15 56.4 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF2997 PF11211.8 AAAP01000731.1_2 - 0.0064 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) UPF0253 PF06786.12 AAAP01000731.1_2 - 0.16 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) Gln-synt_C PF00120.24 AAAP01000732.1_2 - 2.3e-07 30.1 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Acyl-CoA_dh_N PF02771.16 AAAP01000733.1_1 - 0.003 18.2 0.0 0.0038 17.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FCD PF07729.12 AAAP01000734.1_2 - 5.6e-23 81.7 12.6 5.6e-23 81.7 12.6 1.6 2 0 0 2 2 2 1 FCD domain Alpha-amylase PF00128.24 AAAP01000735.1_1 - 1.4e-08 34.7 0.2 0.0037 16.9 0.0 2.1 1 1 0 2 2 2 2 Alpha amylase, catalytic domain CbiM PF01891.16 AAAP01000736.1_1 - 2.5e-26 92.8 26.2 2.5e-26 92.8 26.2 2.7 2 1 0 2 2 2 1 Cobalt uptake substrate-specific transmembrane region PDGLE PF13190.6 AAAP01000736.1_1 - 3e-07 30.3 6.4 3e-07 30.3 6.4 3.3 3 2 0 3 3 3 1 PDGLE domain Beta_elim_lyase PF01212.21 AAAP01000738.1_2 - 1.1e-20 74.1 0.4 1.2e-20 74.0 0.4 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_31 PF13560.6 AAAP01000739.1_1 - 0.00055 20.2 0.1 0.00075 19.8 0.1 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01000739.1_1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_3 PF01381.22 AAAP01000739.1_1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix HTH_17 PF12728.7 AAAP01000739.1_1 - 0.051 13.8 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain cNMP_binding PF00027.29 AAAP01000740.1_1 - 3.3e-10 39.9 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HHH_3 PF12836.7 AAAP01000741.1_1 - 3.2e-27 94.6 0.0 6.3e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 AAAP01000741.1_1 - 2.5e-23 82.7 0.0 7.3e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 HHH domain Tex_YqgF PF16921.5 AAAP01000741.1_1 - 6e-18 65.5 0.7 1.9e-17 63.9 0.3 2.0 2 0 0 2 2 2 1 Tex protein YqgF-like domain HHH PF00633.23 AAAP01000741.1_1 - 2.8e-08 33.2 0.2 0.011 15.6 0.0 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_7 PF14635.6 AAAP01000741.1_1 - 9.8e-08 32.3 0.0 2.3e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_6 PF14579.6 AAAP01000741.1_1 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.8 1 1 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 AAAP01000741.1_1 - 0.00026 20.5 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_5 PF14520.6 AAAP01000741.1_1 - 0.00031 21.3 1.1 0.016 15.8 0.2 3.4 2 2 1 3 3 3 2 Helix-hairpin-helix domain YqgF PF14639.6 AAAP01000741.1_1 - 0.00057 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_8 PF14716.6 AAAP01000741.1_1 - 0.017 15.5 0.0 9.9 6.6 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain FHA PF00498.26 AAAP01000743.1_1 - 3.4e-09 36.9 0.0 4.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AAAP01000743.1_1 - 2.8e-05 24.3 0.0 4.3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF1905 PF08922.11 AAAP01000743.1_1 - 0.092 12.8 0.2 0.73 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) PP2C_2 PF13672.6 AAAP01000743.1_2 - 4.6e-09 36.2 0.4 6.4e-09 35.7 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AAAP01000743.1_2 - 0.0099 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C NUDIX_2 PF13869.6 AAAP01000743.1_2 - 0.017 14.7 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase H_PPase PF03030.16 AAAP01000744.1_1 - 1.2e-43 149.7 3.3 1.4e-43 149.6 3.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase ASFV_J13L PF05568.11 AAAP01000744.1_2 - 0.12 12.1 0.4 0.16 11.7 0.4 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein Bac_luciferase PF00296.20 AAAP01000745.1_2 - 1e-12 48.1 0.5 1.1e-12 48.0 0.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase VbhA PF18495.1 AAAP01000746.1_1 - 0.0026 17.6 0.1 0.0026 17.6 0.1 2.4 3 0 0 3 3 3 1 Antitoxin VbhA PfkB PF00294.24 AAAP01000747.1_1 - 1.5e-10 40.8 0.5 3e-10 39.9 0.5 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AAAP01000747.1_1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Lyase_1 PF00206.20 AAAP01000749.1_1 - 2.8e-26 92.7 0.0 3.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AAAP01000749.1_1 - 0.00069 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AAAP01000749.1_1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal SQHop_cyclase_C PF13243.6 AAAP01000750.1_1 - 2.1e-05 23.8 0.1 2.3e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_C PF13243.6 AAAP01000750.1_2 - 1.6e-28 99.7 0.0 2.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain DnaJ_CXXCXGXG PF00684.19 AAAP01000751.1_1 - 7.2e-27 93.5 74.4 4.3e-09 36.6 6.5 4.2 1 1 4 5 5 5 5 DnaJ central domain Anti-TRAP PF15777.5 AAAP01000751.1_1 - 1.6e-15 56.8 50.5 0.00069 19.5 2.3 6.3 5 1 1 6 6 6 6 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 AAAP01000751.1_1 - 0.0017 18.7 48.7 0.026 14.9 0.8 8.2 3 3 4 7 7 7 4 Restriction alleviation protein Lar CpXC PF14353.6 AAAP01000751.1_1 - 0.096 12.7 0.1 0.096 12.7 0.1 6.0 1 1 6 8 8 8 0 CpXC protein Peripla_BP_7 PF18610.1 AAAP01000751.1_1 - 0.22 11.7 0.0 41 4.4 0.0 2.9 3 0 0 3 3 3 0 Periplasmic binding protein domain C1_2 PF03107.16 AAAP01000751.1_1 - 0.35 11.2 0.3 0.35 11.2 0.3 5.4 5 2 1 6 6 6 0 C1 domain DZR PF12773.7 AAAP01000751.1_1 - 0.39 10.8 34.6 2.3 8.3 7.4 4.6 1 1 2 3 3 3 0 Double zinc ribbon Elf1 PF05129.13 AAAP01000751.1_1 - 0.54 10.3 0.0 0.54 10.3 0.0 5.2 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like DUF1356 PF07092.12 AAAP01000751.1_1 - 0.59 9.4 25.3 1.9 7.7 0.4 6.4 2 2 5 7 7 7 0 Protein of unknown function (DUF1356) Prim_Zn_Ribbon PF08273.12 AAAP01000751.1_1 - 2.8 8.3 83.0 1.4 9.3 0.7 11.2 9 2 2 11 11 11 0 Zinc-binding domain of primase-helicase ArfA PF03889.13 AAAP01000752.1_2 - 1.3e-10 40.6 0.4 1.6e-10 40.3 0.4 1.1 1 0 0 1 1 1 1 Alternative ribosome-rescue factor A SLT_2 PF13406.6 AAAP01000752.1_3 - 2.7e-09 36.7 0.1 3.3e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain ox_reductase_C PF08635.10 AAAP01000752.1_3 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain fn3 PF00041.21 AAAP01000754.1_1 - 1.7e-21 76.3 2.0 3.2e-09 37.0 0.0 4.1 3 1 0 3 3 3 3 Fibronectin type III domain Y_Y_Y PF07495.13 AAAP01000754.1_1 - 1.6e-07 31.2 0.2 0.00026 20.9 0.0 4.0 4 0 0 4 4 4 1 Y_Y_Y domain FlgD_ig PF13860.6 AAAP01000754.1_1 - 0.01 15.7 3.6 0.01 15.7 3.6 4.3 4 1 0 4 4 4 0 FlgD Ig-like domain PKD PF00801.20 AAAP01000754.1_1 - 0.02 14.7 8.4 4.4 7.2 0.1 4.0 3 1 0 3 3 3 0 PKD domain He_PIG PF05345.12 AAAP01000754.1_1 - 0.02 15.0 17.5 0.25 11.6 2.8 4.3 4 1 0 4 4 4 0 Putative Ig domain fn3_2 PF16893.5 AAAP01000754.1_1 - 0.031 14.4 0.1 0.085 13.0 0.0 1.7 2 0 0 2 2 2 0 Fibronectin type III domain SusE PF14292.6 AAAP01000754.1_1 - 0.035 14.3 9.2 7.1 6.9 0.2 3.2 2 1 1 3 3 3 0 SusE outer membrane protein Cadherin PF00028.17 AAAP01000754.1_1 - 0.069 13.6 0.3 30 5.2 0.0 3.0 4 0 0 4 4 4 0 Cadherin domain DUF4998 PF16389.5 AAAP01000754.1_1 - 0.1 12.2 0.0 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function ChitinaseA_N PF08329.10 AAAP01000754.1_1 - 0.15 11.7 0.6 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Invasin_D3 PF09134.10 AAAP01000754.1_1 - 0.19 12.0 17.8 0.043 14.1 4.6 3.3 2 1 0 3 3 3 0 Invasin, domain 3 CarboxypepD_reg PF13620.6 AAAP01000754.1_1 - 0.9 9.9 15.1 0.81 10.0 7.8 3.7 3 1 0 3 3 2 0 Carboxypeptidase regulatory-like domain SpaA PF17802.1 AAAP01000754.1_1 - 1.5 9.2 6.6 2.1 8.7 4.8 2.3 1 1 0 1 1 1 0 Prealbumin-like fold domain HTH_3 PF01381.22 AAAP01000756.1_1 - 2.7e-08 33.8 0.1 3.3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01000756.1_1 - 2.2e-07 31.1 0.3 2.4e-07 31.0 0.3 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01000756.1_1 - 0.0017 18.4 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01000756.1_1 - 0.026 14.5 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AAAP01000756.1_1 - 0.053 13.6 0.1 0.053 13.6 0.1 1.0 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Aminotran_5 PF00266.19 AAAP01000757.1_1 - 3.7e-32 111.7 0.0 4.5e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PHY PF00360.20 AAAP01000757.1_1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Phytochrome region HTH_31 PF13560.6 AAAP01000757.1_1 - 9 6.7 11.9 10 6.6 0.1 3.7 3 1 0 3 3 3 0 Helix-turn-helix domain DUF1080 PF06439.11 AAAP01000758.1_1 - 3.6e-06 27.2 1.5 0.015 15.4 0.3 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.24 AAAP01000758.1_1 - 0.00022 21.8 0.1 0.029 14.9 0.0 2.3 2 1 0 2 2 2 2 Laminin G domain DUF1508 PF07411.12 AAAP01000758.1_1 - 0.039 13.8 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Amidohydro_1 PF01979.20 AAAP01000760.1_2 - 8.6e-41 140.4 2.0 1.1e-40 140.0 2.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AAAP01000760.1_2 - 3e-27 95.4 0.0 4.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AAAP01000760.1_2 - 0.0021 17.6 2.6 0.0058 16.1 0.6 2.0 1 1 1 2 2 2 1 Amidohydrolase family Abhydrolase_6 PF12697.7 AAAP01000762.1_1 - 0.00026 21.6 3.1 0.00029 21.5 3.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01000762.1_1 - 0.065 12.9 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 AAAP01000763.1_1 - 1.3e-09 37.5 8.2 1.4e-09 37.3 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 AAAP01000763.1_1 - 0.15 10.3 0.9 0.18 10.1 0.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hydrolase_4 PF12146.8 AAAP01000763.1_2 - 3.4e-07 29.8 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01000763.1_2 - 1.7e-06 27.9 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01000763.1_2 - 7.7e-06 26.7 0.7 1.3e-05 25.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AAAP01000763.1_2 - 0.04 12.8 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme SIS PF01380.22 AAAP01000764.1_1 - 3.7e-33 114.1 0.9 1.1e-27 96.4 0.1 2.1 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 AAAP01000764.1_1 - 0.033 14.2 0.3 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 SIS domain MinC_C PF03775.16 AAAP01000764.1_1 - 0.14 12.2 1.3 0.46 10.5 0.3 2.0 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain MFS_1 PF07690.16 AAAP01000766.1_1 - 9.8e-24 83.9 39.3 1.2e-23 83.7 39.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01000766.1_1 - 8.4e-06 24.9 11.7 1.3e-05 24.3 11.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 AAAP01000766.1_1 - 0.66 8.2 5.5 0.38 9.0 0.0 2.5 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Gp_dh_N PF00044.24 AAAP01000767.1_1 - 8.3e-38 128.8 0.1 1.1e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAAP01000767.1_1 - 0.001 19.6 0.1 0.0018 18.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 AAAP01000767.1_1 - 0.0042 17.2 0.3 0.01 15.9 0.2 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 AAAP01000767.1_1 - 0.0085 16.7 0.3 0.023 15.4 0.3 1.6 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAAP01000767.1_1 - 0.063 14.1 0.3 0.2 12.5 0.3 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.21 AAAP01000767.1_1 - 0.071 12.4 0.1 0.075 12.4 0.1 1.1 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 AAAP01000767.1_1 - 0.1 12.8 0.2 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAAP01000767.1_1 - 0.12 11.8 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PhnG PF06754.12 AAAP01000768.1_1 - 0.0072 16.3 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG ABC_tran PF00005.27 AAAP01000768.1_2 - 5.4e-05 23.7 0.0 5.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Radical_SAM PF04055.21 AAAP01000769.1_1 - 7.1e-15 55.8 0.0 2e-14 54.3 0.0 1.6 1 1 1 2 2 2 1 Radical SAM superfamily DUF3357 PF11837.8 AAAP01000770.1_1 - 0.028 14.9 0.1 0.034 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) CtaG_Cox11 PF04442.14 AAAP01000770.1_2 - 4.6e-13 49.5 0.0 5.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Phostensin_N PF13916.6 AAAP01000771.1_1 - 0.18 12.1 5.8 1.1 9.7 3.2 2.2 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RNase_T PF00929.24 AAAP01000772.1_1 - 1.5e-08 35.4 0.0 3.1e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Exonuclease DSBA PF01323.20 AAAP01000772.1_1 - 0.18 11.5 1.0 5.6 6.7 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF2986 PF11661.8 AAAP01000772.1_1 - 0.2 12.2 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) DUF983 PF06170.12 AAAP01000773.1_1 - 5.9e-31 106.7 6.1 6.3e-31 106.6 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF983) Zn-ribbon_8 PF09723.10 AAAP01000773.1_1 - 0.0052 16.9 1.3 0.52 10.5 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain zf-RRN7 PF11781.8 AAAP01000773.1_1 - 0.017 14.8 2.5 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4229 PF14012.6 AAAP01000773.1_1 - 0.019 15.0 3.2 0.027 14.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF1272 PF06906.11 AAAP01000773.1_1 - 0.045 13.8 0.2 5.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C4_Topoisom PF01396.19 AAAP01000773.1_1 - 0.083 12.7 0.4 3.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_5 PF13719.6 AAAP01000773.1_1 - 0.1 12.4 1.7 8.9 6.2 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AAAP01000773.1_1 - 0.2 11.1 2.4 1.7 8.2 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 AAAP01000773.1_1 - 0.53 10.0 4.8 0.95 9.2 0.7 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain CrgA PF06781.12 AAAP01000773.1_1 - 1.1 9.4 3.2 2.1 8.4 3.2 1.5 1 1 0 1 1 1 0 Cell division protein CrgA SURF1 PF02104.15 AAAP01000773.1_2 - 3.6e-19 69.7 0.0 4.1e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 SURF1 family SelB-wing_2 PF09106.11 AAAP01000773.1_2 - 0.12 12.6 0.1 7.4 6.9 0.0 2.8 2 2 0 2 2 2 0 Elongation factor SelB, winged helix XdhC_C PF13478.6 AAAP01000774.1_1 - 4.6e-20 72.4 0.1 6e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 XdhC Rossmann domain TrkA_N PF02254.18 AAAP01000774.1_1 - 0.043 14.1 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sex_peptide PF08138.11 AAAP01000775.1_2 - 0.052 13.7 0.1 0.072 13.2 0.1 1.4 1 1 0 1 1 1 0 Sex peptide (SP) family Carbam_trans_N PF02543.15 AAAP01000776.1_1 - 1.8e-55 189.0 0.0 1.5e-53 182.7 0.0 2.1 1 1 0 1 1 1 1 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 AAAP01000776.1_1 - 0.035 13.8 0.0 5 6.7 0.0 2.7 2 1 0 2 2 2 0 Glycoprotease family ETF PF01012.21 AAAP01000777.1_1 - 0.021 14.7 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain AvrE_T3Es PF11725.8 AAAP01000777.1_1 - 0.28 8.3 0.0 0.32 8.2 0.0 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) RNase_T PF00929.24 AAAP01000778.1_1 - 1.3e-12 48.6 0.0 1.8e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 AAAP01000778.1_1 - 0.01 15.6 0.1 0.23 11.1 0.0 2.5 2 1 0 2 2 2 0 3'-5' exonuclease CHDCT2 PF08074.11 AAAP01000779.1_2 - 0.093 12.9 2.4 0.15 12.3 2.4 1.6 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain Bac_DnaA PF00308.18 AAAP01000781.1_1 - 1e-68 231.5 0.0 1.6e-68 230.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AAAP01000781.1_1 - 9.8e-17 60.8 0.3 2.9e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 AAAP01000781.1_1 - 1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 AAAP01000781.1_1 - 0.002 18.5 0.7 0.0046 17.3 0.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AFG1_ATPase PF03969.16 AAAP01000781.1_1 - 0.0036 16.2 0.1 0.0084 15.0 0.1 1.6 1 1 0 1 1 1 1 AFG1-like ATPase AAA PF00004.29 AAAP01000781.1_1 - 0.01 16.2 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAAP01000781.1_1 - 0.032 14.3 0.0 0.084 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAAP01000781.1_1 - 0.073 13.3 0.9 5.8 7.2 0.0 2.6 2 1 1 3 3 3 0 AAA domain YkuD PF03734.14 AAAP01000782.1_1 - 5e-11 43.2 0.0 6.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Abhydrolase_1 PF00561.20 AAAP01000783.1_1 - 5.5e-06 26.2 0.0 6.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1849 PF08904.11 AAAP01000785.1_1 - 1.6e-25 90.1 0.0 1.8e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1849) DUF4763 PF15960.5 AAAP01000786.1_1 - 0.0021 17.4 8.1 0.0028 17.0 8.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) ABC_tran_CTD PF16326.5 AAAP01000786.1_1 - 0.0024 18.1 5.2 0.0024 18.1 5.2 2.4 2 1 0 2 2 2 1 ABC transporter C-terminal domain DUF4559 PF15112.6 AAAP01000786.1_1 - 0.016 14.9 5.3 0.024 14.4 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DASH_Hsk3 PF08227.11 AAAP01000786.1_1 - 0.021 15.2 0.2 0.021 15.2 0.2 2.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like PhageMin_Tail PF10145.9 AAAP01000786.1_1 - 0.031 14.1 0.2 0.07 13.0 0.2 1.5 1 1 0 1 1 1 0 Phage-related minor tail protein Sec34 PF04136.15 AAAP01000786.1_1 - 0.1 12.5 8.1 1.8 8.4 1.3 2.2 2 0 0 2 2 2 0 Sec34-like family FlxA PF14282.6 AAAP01000786.1_1 - 0.13 12.3 12.8 0.029 14.3 8.5 2.0 2 0 0 2 2 2 0 FlxA-like protein ThiS PF02597.20 AAAP01000786.1_1 - 0.16 12.6 0.5 1.1 10.0 0.5 2.3 1 1 0 1 1 1 0 ThiS family FlaC_arch PF05377.11 AAAP01000786.1_1 - 0.21 12.0 3.2 0.81 10.1 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 AAAP01000786.1_1 - 0.22 11.1 8.7 0.7 9.4 1.1 2.3 1 1 1 2 2 2 0 fzo-like conserved region EMP24_GP25L PF01105.24 AAAP01000786.1_1 - 0.24 11.3 8.8 0.4 10.6 2.8 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 AAAP01000786.1_1 - 0.25 11.4 11.4 0.34 11.0 10.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 AAAP01000786.1_1 - 0.3 10.4 6.7 0.38 10.1 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein LXG PF04740.12 AAAP01000786.1_1 - 0.35 10.6 7.3 0.58 9.8 6.9 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF745 PF05335.13 AAAP01000786.1_1 - 0.36 10.5 15.3 0.43 10.3 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4407 PF14362.6 AAAP01000786.1_1 - 0.46 9.8 8.5 0.61 9.4 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 AAAP01000786.1_1 - 0.49 10.7 11.6 0.081 13.2 2.5 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3106 PF11304.8 AAAP01000786.1_1 - 0.74 10.3 10.0 0.32 11.5 4.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Neuropep_like PF15161.6 AAAP01000786.1_1 - 0.83 9.4 4.1 3.4 7.4 0.4 2.6 2 0 0 2 2 2 0 Neuropeptide-like DUF2730 PF10805.8 AAAP01000786.1_1 - 0.84 9.8 5.7 0.5 10.5 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Fungal_trans_2 PF11951.8 AAAP01000786.1_1 - 1.4 7.6 4.8 1.7 7.3 3.6 1.6 1 1 1 2 2 2 0 Fungal specific transcription factor domain DUF948 PF06103.11 AAAP01000786.1_1 - 2.2 8.6 4.6 3 8.2 0.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 AAAP01000786.1_1 - 2.6 8.1 15.0 0.18 11.8 8.0 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 AAAP01000786.1_1 - 3 7.7 13.0 0.91 9.3 4.1 2.8 1 1 0 2 2 2 0 Septum formation initiator ACCA PF03255.14 AAAP01000786.1_1 - 4.3 7.2 7.7 0.39 10.6 1.4 2.1 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FUSC PF04632.12 AAAP01000786.1_1 - 4.5 5.7 12.0 6.8 5.1 12.0 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.6 AAAP01000786.1_1 - 4.7 7.7 15.0 3.6 8.1 2.8 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2203 PF09969.9 AAAP01000786.1_1 - 4.9 7.9 10.1 1.4 9.7 1.6 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 AAAP01000786.1_1 - 6.1 6.3 11.6 9.2 5.7 11.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.8 AAAP01000786.1_1 - 9.4 6.6 14.0 2.1 8.7 4.2 2.2 1 1 1 2 2 2 0 YlqD protein Glyco_hydro_65m PF03632.15 AAAP01000787.1_1 - 4.7e-43 147.5 0.4 5.7e-43 147.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain LacAB_rpiB PF02502.18 AAAP01000792.1_1 - 9.5e-34 116.4 0.1 1.1e-33 116.2 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Peptidase_M13_N PF05649.13 AAAP01000792.1_2 - 3.4e-17 63.2 0.0 3.9e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 Toxin_trans PF07952.12 AAAP01000792.1_2 - 0.33 10.0 0.0 0.42 9.6 0.0 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Radical_SAM PF04055.21 AAAP01000793.1_1 - 0.00097 19.5 0.0 0.0012 19.3 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily DUF4070 PF13282.6 AAAP01000793.1_1 - 0.0013 18.8 0.1 0.0022 18.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) Biotin_lipoyl_2 PF13533.6 AAAP01000794.1_1 - 0.0001 22.1 0.2 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like GAF_2 PF13185.6 AAAP01000794.1_1 - 0.00054 20.3 0.7 0.0015 18.8 0.1 1.9 2 1 0 2 2 2 1 GAF domain GAF PF01590.26 AAAP01000794.1_1 - 0.0012 19.5 0.4 0.012 16.3 0.0 2.2 2 1 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAAP01000794.1_1 - 0.0063 16.9 0.2 0.015 15.7 0.1 1.7 2 0 0 2 2 2 1 GAF domain HlyD_D23 PF16576.5 AAAP01000794.1_1 - 0.017 14.3 0.3 0.029 13.6 0.3 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion E1-E2_ATPase PF00122.20 AAAP01000796.1_1 - 1.9e-52 177.4 0.1 3e-52 176.8 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01000796.1_1 - 5.5e-06 26.8 0.2 1.8e-05 25.1 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF881 PF05949.12 AAAP01000797.1_1 - 4.3e-23 81.8 0.0 4.9e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) Phage_integrase PF00589.22 AAAP01000798.1_1 - 2.4e-05 24.2 0.0 3.6e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family UvrD_C PF13361.6 AAAP01000799.1_1 - 2.1e-37 129.3 0.0 2.8e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AAAP01000799.1_1 - 4.1e-13 49.5 0.0 6.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAAP01000799.1_1 - 0.03 14.6 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bmp PF02608.14 AAAP01000800.1_1 - 2.5e-43 148.2 0.1 2.8e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Ribosomal_L35p PF01632.19 AAAP01000801.1_1 - 8.9e-12 45.3 1.0 1e-11 45.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 GSDH PF07995.11 AAAP01000802.1_1 - 9.3e-31 107.3 0.0 1.1e-30 107.1 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Epimerase PF01370.21 AAAP01000804.1_1 - 9.4e-16 58.0 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01000804.1_1 - 5e-14 52.4 0.0 6.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AAA_lid_2 PF17863.1 AAAP01000804.1_1 - 0.0031 17.3 0.7 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA lid domain Peptidase_C42 PF05533.12 AAAP01000804.1_1 - 0.012 15.6 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 NmrA PF05368.13 AAAP01000804.1_1 - 0.087 12.4 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 AAAP01000804.1_2 - 2.3e-11 43.7 0.0 2.6e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01000804.1_2 - 5.3e-11 42.4 0.3 6e-11 42.3 0.3 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAAP01000804.1_2 - 1.2e-08 34.3 0.0 1.3e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AAAP01000804.1_2 - 6.8e-08 32.2 0.0 8.2e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01000804.1_2 - 1e-06 28.8 0.0 1.2e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 AAAP01000804.1_2 - 1.6e-06 27.5 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_8 PF13450.6 AAAP01000804.1_2 - 0.00024 21.3 0.1 0.00034 20.8 0.1 1.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain adh_short_C2 PF13561.6 AAAP01000804.1_2 - 0.00055 19.6 0.1 0.00063 19.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 AAAP01000804.1_2 - 0.0018 18.5 0.1 0.002 18.4 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 AAAP01000804.1_2 - 0.0035 16.5 0.0 0.0042 16.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAAP01000804.1_2 - 0.0094 15.9 0.6 0.013 15.4 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding PIN_10 PF18478.1 AAAP01000804.1_2 - 0.012 15.8 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 PIN like domain NmrA PF05368.13 AAAP01000804.1_2 - 0.018 14.6 0.1 0.022 14.3 0.1 1.1 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 AAAP01000804.1_2 - 0.14 11.3 0.7 0.63 9.2 0.7 1.9 1 1 0 1 1 1 0 Male sterility protein DUF3043 PF11241.8 AAAP01000806.1_2 - 2.4e-60 203.5 7.0 2.9e-60 203.2 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) stn_TNFRSF12A PF12191.8 AAAP01000806.1_2 - 0.17 12.1 0.3 0.39 10.9 0.3 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Thioredox_DsbH PF03190.15 AAAP01000807.1_1 - 1.1e-63 214.0 0.0 1.3e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 AAAP01000807.1_1 - 6.9e-11 42.2 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Acyl-CoA_dh_N PF02771.16 AAAP01000808.1_1 - 1.4e-32 112.7 1.3 1.6e-32 112.5 1.3 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01000808.1_1 - 2.1e-05 24.6 0.1 6.4e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain A-2_8-polyST PF07388.11 AAAP01000809.1_1 - 0.24 9.9 0.0 0.27 9.8 0.0 1.0 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) CBM_4_9 PF02018.17 AAAP01000811.1_1 - 1.3e-11 44.9 0.1 1.6e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain ABC_membrane PF00664.23 AAAP01000813.1_1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region Pox_P21 PF05313.12 AAAP01000813.1_1 - 1.7 8.2 7.2 1.1 8.8 1.2 2.4 2 0 0 2 2 2 0 Poxvirus P21 membrane protein TonB_dep_Rec PF00593.24 AAAP01000814.1_1 - 1.7e-05 24.9 2.4 1.7e-05 24.9 2.4 1.1 1 0 0 1 1 1 1 TonB dependent receptor PTS_IIB PF02302.17 AAAP01000815.1_1 - 2.7e-19 69.7 0.7 3.3e-19 69.4 0.7 1.1 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit Bax1-I PF01027.20 AAAP01000816.1_1 - 0.016 15.0 9.8 0.02 14.7 9.8 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Peptidase_M20 PF01546.28 AAAP01000817.1_1 - 7.6e-13 48.6 0.7 1e-12 48.2 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAAP01000817.1_1 - 5.8e-05 23.0 0.0 0.00024 21.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAAP01000817.1_1 - 0.00016 21.4 0.1 0.00023 20.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 AAAP01000817.1_1 - 0.086 11.9 0.0 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Fer4_8 PF13183.6 AAAP01000818.1_1 - 8.6e-10 38.9 1.4 1.7e-09 38.0 1.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01000818.1_1 - 5.4e-09 36.5 1.4 9e-09 35.8 1.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01000818.1_1 - 2.6e-05 24.7 0.2 4.9e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01000818.1_1 - 0.00032 20.4 2.0 0.00067 19.4 2.0 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01000818.1_1 - 0.00097 19.2 0.7 0.0047 17.0 0.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01000818.1_1 - 0.0076 16.4 2.4 0.018 15.2 2.5 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01000818.1_1 - 0.016 15.3 2.8 0.038 14.1 2.8 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01000818.1_1 - 0.017 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01000818.1_1 - 0.019 15.4 3.7 0.05 14.1 3.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01000818.1_1 - 0.052 13.7 2.7 0.11 12.6 2.7 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain TPR_14 PF13428.6 AAAP01000818.1_1 - 0.12 13.3 1.6 1.8 9.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01000818.1_1 - 1.5 9.7 6.8 0.43 11.4 1.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Tex_N PF09371.10 AAAP01000819.1_1 - 1e-67 227.3 0.2 1.2e-67 227.1 0.2 1.0 1 0 0 1 1 1 1 Tex-like protein N-terminal domain FUSC PF04632.12 AAAP01000819.1_1 - 1.3 7.5 8.3 2.2 6.7 8.3 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Radical_SAM PF04055.21 AAAP01000821.1_1 - 8.8e-11 42.5 0.1 3e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily FA_synthesis PF02504.15 AAAP01000822.1_1 - 4.7e-60 203.3 1.2 5.3e-60 203.2 1.2 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein DctP PF03480.13 AAAP01000823.1_1 - 8.2e-40 136.9 0.0 9.1e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Glyco_hydro_15 PF00723.21 AAAP01000824.1_1 - 0.12 11.2 0.3 0.16 10.7 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 GATase PF00117.28 AAAP01000827.1_1 - 5.1e-26 91.6 0.0 6.3e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 AAAP01000827.1_1 - 1.7e-07 30.9 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GGDEF_2 PF17853.1 AAAP01000827.1_1 - 0.026 14.8 0.0 0.16 12.2 0.0 1.9 1 1 1 2 2 2 0 GGDEF-like domain Peptidase_C26 PF07722.13 AAAP01000827.1_1 - 0.074 12.8 0.1 0.2 11.4 0.0 1.7 1 1 1 2 2 2 0 Peptidase C26 Polbeta PF18765.1 AAAP01000829.1_1 - 3.8e-11 42.9 0.0 5.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AAAP01000829.1_1 - 6.1e-10 39.3 0.0 7.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_transf PF04439.12 AAAP01000829.1_1 - 0.00064 18.9 0.0 0.00066 18.9 0.0 1.1 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Glyco_hydro_42M PF08532.10 AAAP01000829.1_1 - 0.0052 16.3 0.0 0.006 16.1 0.0 1.0 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain DUF294 PF03445.13 AAAP01000829.1_1 - 0.014 15.2 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 HEPN PF05168.14 AAAP01000829.1_2 - 1.1e-07 32.0 0.3 1.3e-07 31.8 0.3 1.0 1 0 0 1 1 1 1 HEPN domain NPCBM PF08305.11 AAAP01000831.1_1 - 6.7e-30 104.1 0.5 1e-29 103.4 0.5 1.3 1 0 0 1 1 1 1 NPCBM/NEW2 domain Cohesin PF00963.18 AAAP01000831.1_1 - 3.7e-12 46.7 0.1 8.1e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Cohesin domain Bmp PF02608.14 AAAP01000832.1_1 - 0.00069 18.7 0.0 0.00077 18.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Glyco_trans_1_4 PF13692.6 AAAP01000833.1_1 - 5.9e-27 94.7 0.1 1.2e-26 93.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01000833.1_1 - 1.9e-20 73.1 0.0 2.6e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01000833.1_1 - 0.0073 16.3 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01000833.1_1 - 0.094 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Mor PF08765.11 AAAP01000833.1_1 - 0.25 11.4 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family GalP_UDP_transf PF01087.22 AAAP01000836.1_1 - 1e-32 114.0 0.0 1.4e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 AAAP01000836.1_1 - 9.9e-06 25.4 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4931 PF16285.5 AAAP01000836.1_1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) NAD_binding_8 PF13450.6 AAAP01000839.1_1 - 1.8e-07 31.2 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01000839.1_1 - 5.9e-07 28.9 0.2 6.5e-07 28.8 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01000839.1_1 - 1.1e-06 28.2 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01000839.1_1 - 1.8e-06 27.8 0.0 6.3e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAAP01000839.1_1 - 2.7e-05 23.6 1.9 3.5e-05 23.2 1.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01000839.1_1 - 3.3e-05 22.8 1.8 4.8e-05 22.2 1.8 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 AAAP01000839.1_1 - 6.9e-05 22.9 0.7 0.0001 22.3 0.7 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 AAAP01000839.1_1 - 7.2e-05 22.3 0.4 8.4e-05 22.1 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AAAP01000839.1_1 - 8.4e-05 21.8 1.0 0.00011 21.5 1.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 AAAP01000839.1_1 - 0.00015 21.1 0.7 0.0002 20.7 0.7 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AAAP01000839.1_1 - 0.00039 19.8 0.5 0.00049 19.5 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 AAAP01000839.1_1 - 0.0065 15.4 1.4 0.0083 15.0 1.4 1.1 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 AAAP01000839.1_1 - 0.013 14.6 1.0 0.016 14.3 1.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 AAAP01000839.1_1 - 0.02 14.0 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 AAAP01000839.1_1 - 0.066 13.8 0.6 0.5 11.0 1.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 AAAP01000839.1_1 - 0.075 12.3 0.5 0.14 11.4 0.3 1.5 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Chorismate_synt PF01264.21 AAAP01000840.1_1 - 9.6e-11 41.0 0.0 1.1e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase HATPase_c PF02518.26 AAAP01000841.1_1 - 4.2e-20 72.3 0.0 5.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01000841.1_1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Nairo_nucleo PF02477.15 AAAP01000841.1_1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein Acyl-ACP_TE PF01643.17 AAAP01000842.1_1 - 0.00041 19.7 0.1 0.0005 19.4 0.1 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 AAAP01000842.1_1 - 0.00044 20.7 0.1 0.00044 20.7 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MM_CoA_mutase PF01642.22 AAAP01000843.1_1 - 3.1e-50 171.2 0.0 3.4e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase ORF_12_N PF18042.1 AAAP01000843.1_1 - 0.055 13.9 0.0 5.7 7.4 0.0 2.2 2 0 0 2 2 2 0 ORF 12 gene product N-terminal PPDK_N PF01326.19 AAAP01000844.1_1 - 2.5e-25 89.5 0.0 1.3e-22 80.5 0.0 2.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain FlaF PF07309.11 AAAP01000845.1_1 - 9.7e-10 38.5 0.1 1e-09 38.4 0.1 1.0 1 0 0 1 1 1 1 Flagellar protein FlaF LKAAEAR PF15478.6 AAAP01000845.1_1 - 0.15 12.3 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif Flagellin_C PF00700.21 AAAP01000845.1_2 - 3.5e-25 88.2 3.3 4.6e-25 87.8 3.3 1.2 1 0 0 1 1 1 1 Bacterial flagellin C-terminal helical region Response_reg PF00072.24 AAAP01000846.1_1 - 2e-24 85.9 0.0 2.3e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Glyco_transf_4 PF13439.6 AAAP01000846.1_1 - 0.039 13.9 0.1 0.13 12.3 0.1 1.6 1 1 1 2 2 2 0 Glycosyltransferase Family 4 Phage_holin_3_6 PF07332.11 AAAP01000847.1_1 - 0.26 11.3 8.2 0.3 11.1 8.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4781 PF16013.5 AAAP01000847.1_1 - 0.51 9.1 7.3 0.52 9.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Fae PF08714.11 AAAP01000847.1_2 - 1.2e-33 116.3 0.1 1.4e-33 116.1 0.1 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Inositol_P PF00459.25 AAAP01000848.1_1 - 2e-36 125.9 0.4 2.2e-36 125.8 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Malt_amylase_C PF16657.5 AAAP01000849.1_1 - 7.9e-05 22.7 0.0 7.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 AAAP01000849.1_1 - 0.0046 17.2 0.1 0.0048 17.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) GATase_7 PF13537.6 AAAP01000850.1_1 - 1.3e-18 67.1 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01000850.1_1 - 1.2e-13 51.4 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 AAAP01000850.1_2 - 6.3e-26 91.9 0.3 7.4e-26 91.6 0.3 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AAAP01000850.1_2 - 0.033 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AAAP01000850.1_2 - 0.035 12.9 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.17 AAAP01000850.1_2 - 0.2 10.7 0.1 0.22 10.6 0.1 1.1 1 0 0 1 1 1 0 NAD synthase IspD PF01128.19 AAAP01000851.1_1 - 1.3e-25 90.4 0.3 1.5e-25 90.2 0.3 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01000851.1_1 - 2.4e-08 34.5 3.3 2.8e-08 34.3 3.3 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4072 PF13284.6 AAAP01000851.1_1 - 0.042 14.3 2.4 0.39 11.2 2.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4072) MS_channel PF00924.18 AAAP01000853.1_1 - 0.0028 17.2 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel CAP PF00188.26 AAAP01000853.1_2 - 1.9e-12 48.1 0.1 2.7e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ATP-cone PF03477.16 AAAP01000855.1_1 - 1.3e-13 51.3 0.2 1.6e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 ATP cone domain Phage_GPL PF05926.11 AAAP01000855.1_1 - 0.005 16.8 0.1 0.0059 16.6 0.1 1.3 1 0 0 1 1 1 1 Phage head completion protein (GPL) YwiC PF14256.6 AAAP01000855.1_2 - 1.9e-28 99.3 13.9 2.4e-28 99.0 13.9 1.1 1 0 0 1 1 1 1 YwiC-like protein Cyt_bd_oxida_II PF02322.15 AAAP01000855.1_2 - 0.053 12.9 8.8 0.066 12.6 8.8 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF2298 PF10060.9 AAAP01000855.1_2 - 0.12 11.1 8.6 0.14 10.8 8.6 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Acetyltransf_1 PF00583.25 AAAP01000858.1_1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAAP01000858.1_1 - 6.4e-08 32.4 0.1 1.2e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AAAP01000858.1_1 - 2.1e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01000858.1_1 - 1.3e-05 25.5 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01000858.1_1 - 0.032 14.9 0.0 0.046 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MarR_2 PF12802.7 AAAP01000859.1_1 - 2.6e-08 33.6 0.8 0.0012 18.7 0.1 2.5 2 0 0 2 2 2 2 MarR family HTH_IclR PF09339.10 AAAP01000859.1_1 - 1.2e-06 28.2 1.5 0.015 15.1 0.1 2.7 2 0 0 2 2 2 2 IclR helix-turn-helix domain MarR PF01047.22 AAAP01000859.1_1 - 2.9e-05 23.9 0.0 0.0087 16.0 0.0 2.3 2 0 0 2 2 2 1 MarR family GntR PF00392.21 AAAP01000859.1_1 - 0.00071 19.2 0.1 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family AbiEi_4 PF13338.6 AAAP01000859.1_1 - 0.00088 19.4 0.2 0.34 11.1 0.0 2.5 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin HTH_Crp_2 PF13545.6 AAAP01000859.1_1 - 0.0011 18.9 0.2 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 AAAP01000859.1_1 - 0.0013 18.7 0.1 0.017 15.1 0.0 2.7 2 1 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 AAAP01000859.1_1 - 0.0014 18.5 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAAP01000859.1_1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 AAAP01000859.1_1 - 0.0058 16.9 0.0 2.8 8.3 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator HTH_36 PF13730.6 AAAP01000859.1_1 - 0.0074 16.2 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Cdc6_C PF09079.11 AAAP01000859.1_1 - 0.023 14.7 0.0 6.1 6.9 0.0 2.4 2 1 0 2 2 2 0 CDC6, C terminal winged helix domain HTH_24 PF13412.6 AAAP01000859.1_1 - 0.028 14.0 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding LZ_Tnp_IS481 PF13011.6 AAAP01000859.1_1 - 0.032 14.8 0.1 0.088 13.4 0.1 1.8 1 1 0 1 1 1 0 leucine-zipper of insertion element IS481 PaaX PF07848.12 AAAP01000859.1_1 - 0.032 14.5 0.2 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein SgrR_N PF12793.7 AAAP01000859.1_1 - 0.037 14.2 0.1 0.11 12.8 0.0 1.7 1 1 1 2 2 2 0 Sugar transport-related sRNA regulator N-term RepL PF05732.11 AAAP01000859.1_1 - 0.043 13.3 0.0 7.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) RP-C PF03428.13 AAAP01000859.1_1 - 0.045 13.4 0.1 0.43 10.2 0.0 2.2 2 1 0 2 2 2 0 Replication protein C N-terminal domain DUF2250 PF10007.9 AAAP01000859.1_1 - 0.045 13.9 0.0 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_27 PF13463.6 AAAP01000859.1_1 - 0.046 14.2 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 AAAP01000859.1_1 - 0.097 12.8 0.0 6.4 7.0 0.0 2.2 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Tautomerase PF01361.21 AAAP01000859.1_1 - 0.13 12.2 0.6 1.1 9.3 0.0 2.4 3 0 0 3 3 2 0 Tautomerase enzyme HTH_9 PF08221.11 AAAP01000859.1_1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AAA_31 PF13614.6 AAAP01000859.1_2 - 1.2e-15 57.9 0.0 1.3e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01000859.1_2 - 3.3e-11 43.3 0.0 3.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAAP01000859.1_2 - 5.1e-06 25.9 0.0 5.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 AAAP01000859.1_2 - 2.1e-05 24.1 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAAP01000859.1_2 - 4.3e-05 22.9 0.1 5e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AAAP01000859.1_2 - 0.0005 19.6 0.0 0.00053 19.5 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AAAP01000859.1_2 - 0.093 12.2 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Glyco_trans_1_2 PF13524.6 AAAP01000860.1_1 - 0.13 12.7 1.8 0.47 10.9 0.3 1.9 1 1 1 2 2 2 0 Glycosyl transferases group 1 CopC PF04234.12 AAAP01000860.1_2 - 0.074 14.1 0.1 0.15 13.1 0.1 1.5 1 0 0 1 1 1 0 CopC domain PBP_like PF12727.7 AAAP01000862.1_1 - 5.9e-33 113.6 0.0 8.1e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain MoeA_C PF03454.15 AAAP01000862.1_1 - 7.2e-13 48.5 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Hydrolase_4 PF12146.8 AAAP01000863.1_1 - 6.1e-06 25.7 0.0 7.1e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01000863.1_1 - 0.0019 17.9 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 AAAP01000863.1_1 - 0.011 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 AAAP01000863.1_1 - 0.023 14.2 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 AAAP01000863.1_1 - 0.095 12.8 0.0 0.097 12.8 0.0 1.0 1 0 0 1 1 1 0 TAP-like protein QCR10 PF09796.9 AAAP01000864.1_1 - 2.4 8.3 8.1 0.38 10.9 2.0 2.7 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) GIY-YIG PF01541.24 AAAP01000865.1_3 - 4.4e-10 39.7 0.0 5.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-FPG_IleRS PF06827.14 AAAP01000867.1_1 - 0.011 15.5 0.8 0.017 15.0 0.8 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Carla_C4 PF01623.17 AAAP01000867.1_1 - 0.73 9.8 6.6 0.86 9.6 6.6 1.2 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein PseudoU_synth_1 PF01416.20 AAAP01000867.1_3 - 7.2e-23 81.1 0.0 1.1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase adh_short_C2 PF13561.6 AAAP01000868.1_2 - 1.5e-23 83.5 0.3 1.7e-23 83.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01000868.1_2 - 6.7e-07 29.0 0.0 9.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ceramidase_alk PF04734.13 AAAP01000869.1_1 - 0.26 9.9 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal ABC_tran PF00005.27 AAAP01000870.1_1 - 2.1e-26 93.1 0.0 2.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01000870.1_1 - 9.2e-11 42.1 0.0 3.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01000870.1_1 - 0.012 16.1 0.2 0.017 15.6 0.2 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAAP01000870.1_1 - 0.017 14.9 0.2 0.033 13.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 AAAP01000870.1_1 - 0.055 13.1 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01000870.1_1 - 0.1 12.3 0.4 0.18 11.5 0.4 1.6 1 1 0 1 1 1 0 AAA domain MukB PF04310.12 AAAP01000870.1_1 - 0.19 11.5 0.2 0.32 10.8 0.2 1.3 1 0 0 1 1 1 0 MukB N-terminal Trypsin_2 PF13365.6 AAAP01000871.1_1 - 4e-14 53.8 1.4 5e-14 53.5 1.4 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 AAAP01000871.1_1 - 0.00044 20.1 0.1 0.00056 19.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin PF00089.26 AAAP01000871.1_1 - 0.013 15.3 0.1 0.02 14.7 0.1 1.4 1 1 0 1 1 1 0 Trypsin Peptidase_S46 PF10459.9 AAAP01000871.1_1 - 0.02 13.5 0.2 0.044 12.4 0.0 1.6 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 AAAP01000871.1_1 - 0.035 13.6 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Cadherin_4 PF17803.1 AAAP01000871.1_1 - 0.041 14.5 1.6 0.062 13.9 1.6 1.3 1 0 0 1 1 1 0 Bacterial cadherin-like domain UPF0182 PF03699.13 AAAP01000873.1_1 - 4.8e-51 173.8 6.2 5.7e-51 173.6 6.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) MHYT PF03707.16 AAAP01000873.1_1 - 0.06 13.5 1.2 0.06 13.5 1.2 3.8 3 2 1 4 4 4 0 Bacterial signalling protein N terminal repeat DUF2070 PF09843.9 AAAP01000873.1_1 - 0.16 10.2 6.6 0.32 9.2 6.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 AAAP01000874.1_1 - 1e-06 28.0 4.6 1.2e-06 27.8 4.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FeoA PF04023.14 AAAP01000874.1_2 - 8.5e-13 48.4 0.3 1.4e-12 47.7 0.3 1.3 1 1 0 1 1 1 1 FeoA domain Peripla_BP_2 PF01497.18 AAAP01000875.1_1 - 1.5e-19 70.6 0.0 1.8e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein TonB_dep_Rec PF00593.24 AAAP01000875.1_2 - 1.4e-26 94.4 7.7 1.7e-26 94.2 7.7 1.0 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AAAP01000875.1_2 - 0.0023 17.0 0.3 0.0033 16.5 0.3 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family Band_7 PF01145.25 AAAP01000876.1_2 - 2e-14 54.0 0.0 2.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family p450 PF00067.22 AAAP01000877.1_1 - 7.7e-35 120.5 0.0 1.6e-34 119.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 AAAP01000877.1_1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Pentapeptide PF00805.22 AAAP01000878.1_1 - 6.6e-41 137.5 23.8 7.4e-14 51.1 1.4 5.4 1 1 2 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAAP01000878.1_1 - 8.1e-27 93.2 0.0 1.8e-11 44.0 0.0 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AAAP01000878.1_1 - 2.7e-24 85.1 14.1 4.4e-07 30.0 4.5 5.5 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Phage_TAC_6 PF09550.10 AAAP01000879.1_3 - 4e-17 62.4 9.0 4.3e-17 62.3 9.0 1.0 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC FrhB_FdhB_N PF04422.13 AAAP01000879.1_3 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Phage_TAC_11 PF11836.8 AAAP01000879.1_4 - 4.7e-23 81.2 6.7 5.1e-23 81.0 6.7 1.0 1 0 0 1 1 1 1 Phage tail tube protein, GTA-gp10 Phage_tail_2 PF06199.11 AAAP01000879.1_5 - 4.9e-07 29.9 0.0 5.5e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein MMPL PF03176.15 AAAP01000880.1_1 - 2.6e-46 158.1 22.1 3.5e-46 157.7 22.1 1.1 1 0 0 1 1 1 1 MMPL family ACR_tran PF00873.19 AAAP01000880.1_1 - 0.88 7.1 17.0 1.2 6.7 17.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Fumerase_C PF05683.12 AAAP01000881.1_1 - 4e-20 72.0 0.0 4.3e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Fumarase C-terminus oligo_HPY PF08352.12 AAAP01000882.1_1 - 3e-17 62.9 0.2 5.7e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region ABC_tran PF00005.27 AAAP01000882.1_1 - 1.3e-16 61.4 0.0 2.1e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAAP01000882.1_1 - 2.1e-06 27.8 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system zf-dskA_traR PF01258.17 AAAP01000883.1_1 - 2.7e-12 46.4 4.3 3.7e-12 46.0 4.3 1.2 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Sgf11 PF08209.11 AAAP01000883.1_1 - 0.0045 16.5 0.7 0.0076 15.8 0.0 1.7 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DZR PF12773.7 AAAP01000883.1_1 - 0.041 13.9 2.0 0.07 13.2 2.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon DUF3331 PF11811.8 AAAP01000883.1_1 - 0.046 13.6 1.0 0.043 13.7 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) adh_short_C2 PF13561.6 AAAP01000883.1_2 - 7.2e-52 176.3 0.0 8.5e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01000883.1_2 - 3e-42 144.3 0.0 3.6e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase APH PF01636.23 AAAP01000886.1_1 - 8.1e-24 84.9 2.2 1.1e-23 84.4 2.2 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAAP01000886.1_1 - 0.3 10.6 0.0 0.45 10.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SelR PF01641.18 AAAP01000887.1_1 - 6.2e-43 145.7 0.1 7e-43 145.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 AAAP01000887.1_1 - 0.0086 16.2 0.6 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 Yippee-Mis18 PF03226.14 AAAP01000887.1_1 - 0.012 15.8 0.0 0.72 10.1 0.0 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 AAAP01000887.1_1 - 0.047 12.5 0.1 4.1 6.2 0.1 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4239 PF14023.6 AAAP01000889.1_1 - 2.4e-09 37.3 0.3 3.9e-09 36.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) TctB PF07331.11 AAAP01000889.1_1 - 0.054 13.8 4.8 0.15 12.3 1.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2160 PF09928.9 AAAP01000889.1_1 - 0.2 12.0 4.0 1.2 9.5 0.3 2.5 2 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) DUF4131 PF13567.6 AAAP01000889.1_1 - 1.7 8.3 6.7 2.1 8.0 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TetR_N PF00440.23 AAAP01000890.1_1 - 3.8e-09 36.2 0.2 5.2e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family KfrA_N PF11740.8 AAAP01000890.1_1 - 0.07 13.8 0.2 0.092 13.4 0.2 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term FBP_C PF16571.5 AAAP01000890.1_2 - 2.6e-41 140.7 0.0 3e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 FBP C-terminal treble-clef zinc-finger CDPS PF16715.5 AAAP01000891.1_1 - 0.042 13.5 0.3 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase SpoVR PF04293.13 AAAP01000891.1_1 - 0.091 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein CytoC_RC PF02276.18 AAAP01000893.1_1 - 3.8e-96 322.1 0.4 4.6e-96 321.8 0.4 1.0 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit Cytochrome_C7 PF14522.6 AAAP01000893.1_1 - 2.5e-05 24.2 0.3 4.6e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Cytochrom_NNT PF03264.14 AAAP01000893.1_1 - 0.00026 20.8 0.3 0.00046 19.9 0.3 1.3 1 0 0 1 1 1 1 NapC/NirT cytochrome c family, N-terminal region DUF3757 PF12582.8 AAAP01000893.1_1 - 0.027 14.9 0.5 0.049 14.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3757) Paired_CXXCH_1 PF09699.10 AAAP01000893.1_1 - 0.056 13.2 3.9 0.86 9.4 3.9 2.2 1 1 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) TetR_N PF00440.23 AAAP01000893.1_1 - 0.19 11.6 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Cytochrom_c3_2 PF14537.6 AAAP01000893.1_1 - 0.35 11.4 4.0 0.98 9.9 4.0 1.6 1 1 0 1 1 1 0 Cytochrome c3 tRNA-synt_2e PF02091.15 AAAP01000894.1_1 - 3.7e-115 383.9 0.0 4.6e-115 383.7 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit N-glycanase_C PF09113.10 AAAP01000894.1_1 - 0.0014 18.4 0.3 0.0025 17.6 0.3 1.3 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal Glyco_transf_4 PF13439.6 AAAP01000895.1_1 - 2e-06 27.9 0.0 2.3e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01000895.1_1 - 0.0015 19.0 0.2 0.0016 18.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain TEX29 PF15839.5 AAAP01000895.1_1 - 0.17 12.5 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 29 protein Glycos_transf_1 PF00534.20 AAAP01000895.1_2 - 1.3e-25 89.9 0.0 1.7e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01000895.1_2 - 1.2e-21 77.5 0.0 1.8e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01000895.1_2 - 2.8e-09 37.2 0.0 6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01000895.1_2 - 0.00069 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01000895.1_2 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DrsE PF02635.15 AAAP01000897.1_2 - 0.0019 18.5 0.0 0.0035 17.7 0.0 1.4 2 0 0 2 2 2 1 DsrE/DsrF-like family Fanconi_A PF03511.14 AAAP01000897.1_2 - 0.09 12.7 0.0 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Fanconi anaemia group A protein Sacchrp_dh_NADP PF03435.18 AAAP01000898.1_1 - 1.5e-27 96.5 0.1 2.4e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 AAAP01000898.1_1 - 7.2e-12 46.0 0.0 1.1e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain FRD2 PF03197.13 AAAP01000898.1_1 - 0.065 13.5 0.1 0.46 10.8 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage FRD2 protein Epimerase PF01370.21 AAAP01000898.1_1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ParA PF10609.9 AAAP01000899.1_1 - 4.3e-101 337.5 0.2 5.3e-101 337.2 0.2 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AAAP01000899.1_1 - 1.1e-12 48.2 0.0 3.8e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01000899.1_1 - 2.3e-10 40.7 0.3 1e-08 35.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 AAAP01000899.1_1 - 2.5e-08 33.5 0.0 5.1e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AAAP01000899.1_1 - 3.4e-08 33.3 0.0 0.00026 20.5 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AAAP01000899.1_1 - 0.0011 18.3 3.8 0.0021 17.3 0.7 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.11 AAAP01000899.1_1 - 0.0047 16.3 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 VirC1 protein FeS_assembly_P PF01883.19 AAAP01000899.1_1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein AAA_25 PF13481.6 AAAP01000899.1_1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CBP_BcsQ PF06564.12 AAAP01000899.1_1 - 0.029 13.9 0.4 0.44 10.0 0.2 2.3 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 AAAP01000899.1_1 - 0.07 12.1 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AAAP01000899.1_1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 AAAP01000899.1_1 - 0.14 12.0 2.1 11 5.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.20 AAAP01000900.1_1 - 1.2e-20 74.3 0.3 5.7e-20 72.0 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01000900.1_1 - 1.7e-13 51.7 8.9 2.3e-13 51.3 8.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01000900.1_1 - 4.7e-05 22.8 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAAP01000900.1_1 - 0.0016 17.2 0.0 0.0021 16.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family ATP-grasp_2 PF08442.10 AAAP01000901.1_1 - 9.2e-20 71.1 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HD PF01966.22 AAAP01000902.1_1 - 4.1e-15 56.1 0.0 5.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 HD domain Malt_amylase_C PF16657.5 AAAP01000902.1_3 - 0.0034 17.5 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain LYTB PF02401.18 AAAP01000903.1_1 - 3.4e-86 288.8 0.0 3.9e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 LytB protein Polysacc_deac_2 PF04748.13 AAAP01000903.1_1 - 0.046 12.9 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Big_1 PF02369.16 AAAP01000904.1_1 - 0.00069 19.6 3.9 0.0038 17.2 3.1 2.2 1 1 1 2 2 2 1 Bacterial Ig-like domain (group 1) DNA_alkylation PF08713.11 AAAP01000905.1_1 - 2.8e-22 79.5 0.0 3.1e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme HEAT_2 PF13646.6 AAAP01000905.1_1 - 8.1e-05 22.9 1.8 0.00039 20.8 1.8 1.8 1 1 0 1 1 1 1 HEAT repeats PQQ_2 PF13360.6 AAAP01000905.1_2 - 1.5e-05 24.7 2.0 2.8e-05 23.8 2.0 1.5 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 AAAP01000905.1_2 - 0.0001 22.0 0.3 0.41 10.7 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat Amino_oxidase PF01593.24 AAAP01000906.1_1 - 1.5e-13 50.9 0.2 1.7e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAAP01000906.1_1 - 1.2e-12 47.9 0.3 1.8e-12 47.3 0.3 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01000906.1_1 - 5.6e-07 29.0 2.8 9.5e-07 28.2 2.8 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAAP01000906.1_1 - 6.8e-07 28.7 0.7 7.8e-07 28.5 0.7 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01000906.1_1 - 2.8e-05 23.7 0.4 2.8e-05 23.7 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01000906.1_1 - 7.5e-05 21.6 1.5 9e-05 21.3 1.5 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 AAAP01000906.1_1 - 9.1e-05 21.9 0.6 0.00013 21.4 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01000906.1_1 - 0.00013 21.4 0.2 0.00013 21.3 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01000906.1_1 - 0.00017 21.3 1.5 0.00024 20.8 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAAP01000906.1_1 - 0.00079 19.4 0.1 0.0009 19.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 AAAP01000906.1_1 - 0.0011 17.9 0.0 0.0013 17.7 0.0 1.0 1 0 0 1 1 1 1 MCRA family AlaDh_PNT_C PF01262.21 AAAP01000906.1_1 - 0.0015 17.9 0.3 0.0017 17.7 0.3 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAAP01000906.1_1 - 0.0037 16.5 1.0 0.0058 15.9 1.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AAAP01000906.1_1 - 0.0041 17.6 0.1 0.0054 17.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAAP01000906.1_1 - 0.0072 15.4 0.2 0.0084 15.2 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AAAP01000906.1_1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAAP01000906.1_1 - 0.23 11.1 0.6 0.31 10.7 0.6 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 AAAP01000906.1_1 - 0.28 10.8 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SQS_PSY PF00494.19 AAAP01000906.1_2 - 4e-25 88.8 2.2 4.2e-25 88.8 2.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase HMGL-like PF00682.19 AAAP01000907.1_1 - 4.3e-52 177.3 0.0 5.4e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.24 AAAP01000907.1_1 - 0.076 12.4 0.0 19 4.6 0.0 2.9 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel RepA_C PF04796.12 AAAP01000909.1_1 - 8.7e-09 35.6 0.0 1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Plasmid encoded RepA protein Acyltransferase PF01553.21 AAAP01000910.1_2 - 2e-13 50.1 0.0 3.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HTH_1 PF00126.27 AAAP01000911.1_1 - 3.7e-16 58.8 0.3 1.1e-15 57.2 0.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAAP01000911.1_1 - 2.9e-14 52.9 1.7 4.2e-14 52.4 1.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain SnoaL PF07366.12 AAAP01000911.1_2 - 8.1e-08 32.1 0.0 9.8e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 AAAP01000911.1_2 - 0.0003 21.4 0.1 0.00049 20.7 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain ACR_tran PF00873.19 AAAP01000912.1_1 - 7.1e-37 126.6 0.0 8.9e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DinI PF06183.13 AAAP01000912.1_1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 DinI-like family HHH_5 PF14520.6 AAAP01000912.1_1 - 0.1 13.2 0.9 0.52 11.0 0.2 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain HpcH_HpaI PF03328.14 AAAP01000913.1_1 - 4.3e-28 98.0 6.2 1e-27 96.7 6.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01000913.1_1 - 1.7e-09 37.3 0.0 3.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3493 PF11998.8 AAAP01000913.1_2 - 0.03 14.5 0.3 0.035 14.3 0.3 1.1 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 ABC_tran PF00005.27 AAAP01000914.1_1 - 6e-08 33.3 0.0 8.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01000914.1_1 - 0.0004 19.9 0.2 0.00048 19.6 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAAP01000914.1_1 - 0.094 13.0 0.2 0.53 10.5 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit EFG_C PF00679.24 AAAP01000914.1_2 - 9.7e-23 80.0 0.0 1.5e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 AAAP01000914.1_2 - 4.5e-16 58.7 0.0 6.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G, domain IV TerC PF03741.16 AAAP01000915.1_2 - 9.3e-52 175.3 10.8 1.1e-51 175.0 10.8 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family Chs7 PF12271.8 AAAP01000915.1_2 - 1.5 8.2 9.2 0.16 11.3 4.5 1.6 2 0 0 2 2 2 0 Chitin synthase export chaperone ACR_tran PF00873.19 AAAP01000916.1_1 - 4.2e-40 137.3 0.2 5.5e-40 136.9 0.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Inos-1-P_synth PF01658.17 AAAP01000917.1_1 - 4.4e-10 39.8 0.1 6.5e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 AAAP01000917.1_1 - 8.1e-09 35.3 0.0 9.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NnrU PF07298.11 AAAP01000918.1_2 - 4.4e-38 130.9 14.7 4.9e-38 130.8 14.7 1.0 1 0 0 1 1 1 1 NnrU protein 1-cysPrx_C PF10417.9 AAAP01000918.1_2 - 0.11 12.4 0.5 0.17 11.7 0.5 1.3 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin DUF3054 PF11255.8 AAAP01000918.1_2 - 0.11 13.0 8.8 0.053 14.0 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) TPR_21 PF09976.9 AAAP01000918.1_3 - 3e-05 23.8 0.1 3.9e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain COX6A PF02046.15 AAAP01000918.1_3 - 0.09 13.2 0.0 0.099 13.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF3693 PF12472.8 AAAP01000918.1_3 - 0.3 10.8 1.1 0.48 10.1 0.2 1.7 1 1 1 2 2 2 0 Phage related protein TonB_dep_Rec PF00593.24 AAAP01000919.1_1 - 4.3e-31 109.3 8.1 5.5e-31 109.0 8.1 1.0 1 0 0 1 1 1 1 TonB dependent receptor 4HBT PF03061.22 AAAP01000920.1_1 - 2.9e-10 40.4 0.1 7.8e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAAP01000920.1_1 - 1.7e-05 25.2 0.2 0.0015 18.9 0.0 2.0 1 1 1 2 2 2 2 Thioesterase-like superfamily CoA_binding_2 PF13380.6 AAAP01000920.1_2 - 2.5e-22 79.5 0.1 3.1e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain Glycos_transf_2 PF00535.26 AAAP01000921.1_1 - 7.7e-17 61.6 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01000921.1_1 - 4.3e-15 56.2 0.0 6.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01000921.1_1 - 5.8e-10 39.1 0.0 4.1e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01000921.1_1 - 9.4e-07 28.9 0.1 4.3e-06 26.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAAP01000921.1_1 - 3e-06 26.8 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 AAAP01000921.1_1 - 5.8e-05 22.9 0.0 0.00015 21.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family Glyco_transf_7C PF02709.14 AAAP01000921.1_1 - 0.0032 17.1 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase NTP_transf_3 PF12804.7 AAAP01000921.1_1 - 0.0094 16.3 0.2 0.013 15.8 0.1 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain Toprim PF01751.22 AAAP01000922.1_1 - 2e-10 40.8 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain GyrB_insert PF18053.1 AAAP01000922.1_1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain PspC PF04024.12 AAAP01000923.1_1 - 8.7e-08 31.9 7.2 8.7e-08 31.9 7.2 1.9 2 0 0 2 2 2 1 PspC domain Trp_oprn_chp PF09534.10 AAAP01000923.1_1 - 0.23 11.2 10.9 0.24 11.2 10.1 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) WcbI PF18588.1 AAAP01000924.1_1 - 6.7e-36 123.9 0.1 1.3e-35 122.9 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis enzyme WcbI HEM4 PF02602.15 AAAP01000924.1_1 - 0.047 13.0 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Acyl_transf_3 PF01757.22 AAAP01000925.1_1 - 1.3e-12 47.5 9.3 1.6e-12 47.2 9.3 1.1 1 0 0 1 1 1 1 Acyltransferase family NmrA PF05368.13 AAAP01000926.1_1 - 3.5e-06 26.7 0.2 3.9e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 AAAP01000926.1_1 - 2.5e-05 23.9 0.1 3.1e-05 23.6 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01000926.1_1 - 0.0003 20.7 0.2 0.00037 20.4 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AAAP01000926.1_1 - 0.0018 17.3 0.1 0.0021 17.1 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AAAP01000926.1_1 - 0.0031 17.0 0.0 0.0031 16.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AAAP01000926.1_1 - 0.0099 15.1 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Male sterility protein RELT PF12606.8 AAAP01000926.1_1 - 0.012 14.6 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 KR PF08659.10 AAAP01000926.1_1 - 0.041 13.8 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 AAAP01000926.1_1 - 0.055 12.9 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase PriA_3primeBD PF17764.1 AAAP01000926.1_2 - 2.5e-11 43.3 0.0 2.6e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) Kinase-PPPase PF03618.14 AAAP01000927.1_1 - 1.2e-10 41.6 0.1 1.4e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Kinase/pyrophosphorylase DUF563 PF04577.14 AAAP01000927.1_2 - 3.3e-34 118.9 0.0 4.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glycos_transf_2 PF00535.26 AAAP01000928.1_1 - 6.7e-10 39.0 0.0 9.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_49 PF13896.6 AAAP01000928.1_1 - 2.8e-05 23.6 0.0 3e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.9 AAAP01000928.1_1 - 0.00016 21.3 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Oxidored_nitro PF00148.19 AAAP01000929.1_1 - 3.5e-26 91.9 0.0 8.9e-25 87.2 0.0 2.1 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase PCP_red PF08369.10 AAAP01000929.1_1 - 1.1e-06 28.8 6.7 1.1e-06 28.8 6.7 1.8 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Peptidase_M41 PF01434.18 AAAP01000930.1_1 - 4.1e-12 46.3 0.6 5.3e-12 46.0 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M41 GTP_cyclohydroI PF01227.22 AAAP01000930.1_2 - 2.7e-71 238.7 0.1 3.4e-71 238.4 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I ACR_tran PF00873.19 AAAP01000931.1_1 - 1.2e-50 172.2 0.2 1.4e-50 172.0 0.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family AzlC PF03591.14 AAAP01000934.1_1 - 6.5e-13 49.3 1.0 6.5e-13 49.3 1.0 2.2 2 1 1 3 3 3 1 AzlC protein AzlD PF05437.12 AAAP01000934.1_2 - 1.6e-20 73.1 5.7 1.8e-20 72.9 5.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) PAS_4 PF08448.10 AAAP01000935.1_1 - 1.1e-15 57.8 0.1 1.7e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01000935.1_1 - 0.00062 19.7 0.0 0.0093 16.0 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01000935.1_1 - 0.025 14.9 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 AAAP01000935.1_1 - 0.1 12.6 0.1 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 PAS domain Met_synt_B12 PF02965.17 AAAP01000936.1_1 - 8.7e-18 64.8 0.0 1e-17 64.5 0.0 1.0 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain CBM_4_9 PF02018.17 AAAP01000937.1_1 - 3.3e-14 53.3 2.7 5.2e-14 52.7 2.7 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain MAM PF00629.23 AAAP01000937.1_1 - 0.0068 16.3 0.0 0.0098 15.8 0.0 1.2 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Gmad2 PF10648.9 AAAP01000937.1_1 - 0.031 14.5 0.2 0.078 13.2 0.2 1.7 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Secretin PF00263.21 AAAP01000937.1_1 - 0.16 11.6 0.1 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein LysR_substrate PF03466.20 AAAP01000938.1_1 - 1.7e-25 89.6 1.6 2.8e-25 88.9 1.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01000938.1_1 - 8.3e-19 67.3 4.1 1.7e-18 66.3 4.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAAP01000938.1_1 - 0.001 18.9 1.8 0.0015 18.4 0.1 2.1 2 0 0 2 2 2 1 MarR family HTH_Tnp_ISL3 PF13542.6 AAAP01000938.1_1 - 0.0088 15.4 0.1 0.05 13.0 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 AAAP01000938.1_1 - 0.014 15.2 0.6 0.032 14.1 0.6 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain GerE PF00196.19 AAAP01000938.1_1 - 0.03 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01000938.1_1 - 0.035 13.8 0.1 0.078 12.7 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 AAAP01000938.1_1 - 0.037 13.6 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAAP01000938.1_1 - 0.055 13.3 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 AAAP01000938.1_1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 AAAP01000938.1_1 - 0.075 13.3 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_AsnC-type PF13404.6 AAAP01000938.1_1 - 0.096 12.5 0.3 0.096 12.5 0.3 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain ATP-cone PF03477.16 AAAP01000939.1_1 - 5.4e-19 68.6 1.1 5.4e-19 68.6 1.1 1.4 2 0 0 2 2 2 1 ATP cone domain DUF4051 PF13260.6 AAAP01000939.1_1 - 0.04 13.6 3.4 0.09 12.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) ACR_tran PF00873.19 AAAP01000940.1_1 - 3.9e-20 71.2 0.1 4.2e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ACR_tran PF00873.19 AAAP01000941.1_1 - 1.1e-29 102.9 0.0 1.2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3379 PF11859.8 AAAP01000941.1_1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Peptidase_M23 PF01551.22 AAAP01000942.1_1 - 3.2e-05 24.1 0.0 7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M23 LysR_substrate PF03466.20 AAAP01000943.1_1 - 1.7e-25 89.6 0.5 1.9e-25 89.4 0.5 1.0 1 0 0 1 1 1 1 LysR substrate binding domain Toluene_X PF03349.16 AAAP01000945.1_1 - 1.7e-11 43.3 1.0 2.1e-11 43.0 1.0 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) DUF3416 PF11896.8 AAAP01000946.1_1 - 2.1e-46 158.5 1.6 3.1e-46 157.9 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Response_reg PF00072.24 AAAP01000947.1_1 - 2e-24 85.9 0.1 2.2e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain ApbA PF02558.16 AAAP01000947.1_1 - 0.095 12.3 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA COX7a PF02238.15 AAAP01000949.1_1 - 0.044 14.2 0.9 0.046 14.1 0.9 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII CBM_35 PF16990.5 AAAP01000950.1_1 - 1.9e-07 31.3 0.9 2.8e-07 30.8 0.9 1.2 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) CBM60 PF16841.5 AAAP01000950.1_1 - 0.012 16.1 0.9 0.09 13.2 0.2 2.2 1 1 1 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding CBM_6 PF03422.15 AAAP01000950.1_1 - 0.038 14.3 1.9 0.058 13.7 1.9 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) GSDH PF07995.11 AAAP01000951.1_1 - 8.5e-14 51.6 0.7 3.2e-13 49.7 0.7 1.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PQQ_3 PF13570.6 AAAP01000951.1_1 - 0.017 15.6 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain TetR_C_11 PF16859.5 AAAP01000952.1_1 - 7.6e-31 106.8 10.9 9.1e-31 106.5 10.9 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AAAP01000952.1_1 - 8.8e-08 32.2 0.3 1e-07 32.0 0.3 1.2 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_6 PF13977.6 AAAP01000952.1_1 - 8.1e-05 22.8 6.6 0.00015 22.0 6.6 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 AAAP01000952.1_1 - 0.013 15.7 10.6 0.018 15.2 10.6 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_16 PF17920.1 AAAP01000952.1_1 - 0.015 15.6 3.2 0.027 14.7 3.2 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NEL PF14496.6 AAAP01000953.1_1 - 6.3e-14 51.9 0.6 8.4e-14 51.5 0.6 1.2 1 0 0 1 1 1 1 C-terminal novel E3 ligase, LRR-interacting LRR_4 PF12799.7 AAAP01000953.1_1 - 5.7e-08 32.9 2.4 0.00016 22.0 0.2 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 AAAP01000953.1_1 - 4.1e-07 29.7 3.8 0.00024 20.8 0.2 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 AAAP01000953.1_1 - 3.3e-05 23.8 2.4 0.74 10.6 1.1 4.4 2 1 1 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 AAAP01000953.1_1 - 0.0018 18.2 5.7 0.85 9.8 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 AAAP01000953.1_1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeat adh_short_C2 PF13561.6 AAAP01000954.1_1 - 1.6e-32 113.0 0.3 2.4e-31 109.1 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01000954.1_1 - 1.3e-15 57.4 0.1 4.6e-15 55.6 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase SnoaL_2 PF12680.7 AAAP01000954.1_2 - 1.4e-11 44.9 0.3 1.5e-11 44.8 0.3 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAAP01000954.1_2 - 3.4e-05 24.2 0.0 3.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AAAP01000954.1_2 - 3.9e-05 23.9 0.0 4.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAAP01000954.1_2 - 0.00015 21.5 0.0 0.00017 21.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 AAAP01000954.1_2 - 0.00033 20.8 0.1 0.00037 20.6 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 AAAP01000954.1_2 - 0.017 15.7 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain OmpA PF00691.20 AAAP01000955.1_2 - 0.0044 17.4 0.0 0.0051 17.2 0.0 1.0 1 0 0 1 1 1 1 OmpA family ABC_tran_CTD PF16326.5 AAAP01000955.1_3 - 0.0044 17.2 2.3 0.0083 16.4 2.3 1.5 1 0 0 1 1 1 1 ABC transporter C-terminal domain PriC PF07445.12 AAAP01000955.1_3 - 0.014 15.3 1.1 0.019 14.9 1.1 1.2 1 0 0 1 1 1 0 Primosomal replication protein priC FlxA PF14282.6 AAAP01000955.1_3 - 0.018 15.0 2.6 0.028 14.4 2.6 1.3 1 0 0 1 1 1 0 FlxA-like protein PhnG PF06754.12 AAAP01000955.1_3 - 0.025 14.5 0.5 0.04 13.9 0.5 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG ADIP PF11559.8 AAAP01000955.1_3 - 0.029 14.4 1.4 0.04 14.0 1.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Vezatin PF12632.7 AAAP01000955.1_3 - 0.036 13.4 0.2 0.043 13.2 0.2 1.1 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes OmpA PF00691.20 AAAP01000955.1_3 - 0.071 13.5 0.0 0.31 11.4 0.0 2.0 2 1 0 2 2 2 0 OmpA family OmpH PF03938.14 AAAP01000955.1_3 - 0.076 13.4 2.8 0.093 13.1 2.0 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 AAAP01000955.1_3 - 0.19 10.2 4.3 0.22 10.0 4.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 AAAP01000955.1_3 - 0.26 11.9 4.7 0.25 12.0 1.7 2.1 1 1 1 2 2 2 0 SlyX Thioredoxin_7 PF13899.6 AAAP01000956.1_1 - 2.2e-17 63.0 0.0 3.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAAP01000956.1_1 - 0.061 13.8 0.0 0.095 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_3 PF00933.21 AAAP01000957.1_1 - 2e-14 53.7 0.0 2.3e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain AMP-binding PF00501.28 AAAP01000958.1_1 - 3.5e-30 104.9 0.2 4.4e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme SpoIIE PF07228.12 AAAP01000959.1_1 - 2.6e-30 105.8 0.1 3.2e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Gln-synt_C PF00120.24 AAAP01000960.1_1 - 1.9e-72 244.2 0.0 2.1e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain FGGY_N PF00370.21 AAAP01000961.1_1 - 1.2e-42 146.1 0.0 1.6e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ABC_tran PF00005.27 AAAP01000963.1_1 - 5.5e-11 43.1 0.0 8.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 AAAP01000963.1_1 - 0.013 15.7 0.2 0.51 10.6 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FLILHELTA PF10306.9 AAAP01000963.1_1 - 0.19 12.2 0.1 0.26 11.7 0.1 1.2 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA ABC-3 PF00950.17 AAAP01000963.1_2 - 2.2e-13 50.3 2.3 2.2e-13 50.3 1.6 1.3 1 1 0 1 1 1 1 ABC 3 transport family ATP-grasp_5 PF13549.6 AAAP01000964.1_1 - 2e-28 99.4 0.0 3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Response_reg PF00072.24 AAAP01000966.1_1 - 9.9e-10 38.6 0.0 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain ATP-grasp_5 PF13549.6 AAAP01000966.1_1 - 0.092 12.2 0.2 2.7 7.4 0.0 2.0 1 1 1 2 2 2 0 ATP-grasp domain HATPase_c PF02518.26 AAAP01000966.1_2 - 1.1e-14 54.9 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LPP PF04728.13 AAAP01000967.1_1 - 0.19 12.1 2.4 1.4 9.4 0.1 2.5 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF4744 PF15918.5 AAAP01000967.1_2 - 0.072 13.9 1.8 0.094 13.6 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) OprB PF04966.12 AAAP01000968.1_1 - 1.3e-10 41.2 0.0 1.4e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family YkuD PF03734.14 AAAP01000968.1_2 - 2.3e-21 76.8 0.1 2.8e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain SNARE_assoc PF09335.11 AAAP01000969.1_1 - 8e-09 36.0 5.4 8e-09 36.0 5.4 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein CbtB PF09489.10 AAAP01000969.1_1 - 7.3 6.8 6.4 16 5.7 1.2 2.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DsbB PF02600.16 AAAP01000969.1_2 - 1.3e-34 119.7 5.5 1.6e-34 119.4 5.5 1.1 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB DUF2231 PF09990.9 AAAP01000969.1_2 - 6.9 7.2 10.9 2.1 8.9 0.4 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) AA_permease_2 PF13520.6 AAAP01000971.1_1 - 2.4e-20 72.8 25.3 2.8e-20 72.5 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01000971.1_1 - 5.9e-17 61.4 26.9 7.6e-17 61.0 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease INO80_Ies4 PF08193.11 AAAP01000972.1_1 - 0.04 13.9 3.4 0.046 13.7 3.4 1.0 1 0 0 1 1 1 0 INO80 complex subunit Ies4 HTH_8 PF02954.19 AAAP01000972.1_2 - 6.9e-13 48.2 0.6 9.4e-13 47.7 0.6 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 AAAP01000972.1_2 - 0.00045 19.9 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AAAP01000972.1_2 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Phage_AlpA PF05930.12 AAAP01000972.1_2 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) HTH_28 PF13518.6 AAAP01000972.1_2 - 0.01 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01000972.1_2 - 0.017 14.9 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_22 PF13309.6 AAAP01000972.1_2 - 0.017 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_Tnp_1_2 PF13022.6 AAAP01000972.1_2 - 0.023 14.8 0.0 1.3 9.2 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase DnaGprimase_HBD PF16730.5 AAAP01000972.1_2 - 0.024 14.7 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain DUF2089 PF09862.9 AAAP01000972.1_2 - 0.026 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_17 PF12728.7 AAAP01000972.1_2 - 0.036 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AAAP01000972.1_2 - 0.044 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF134 PF02001.16 AAAP01000972.1_2 - 0.045 14.3 0.1 0.066 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 TetR_N PF00440.23 AAAP01000972.1_2 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_50 PF18024.1 AAAP01000972.1_2 - 0.089 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 AAAP01000972.1_2 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 RWP-RK domain CENP-B_N PF04218.13 AAAP01000972.1_2 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HSP20 PF00011.21 AAAP01000973.1_1 - 2.2e-20 72.7 0.0 2.6e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01000973.1_1 - 1e-09 37.8 0.0 1.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA ABC_tran PF00005.27 AAAP01000974.1_1 - 5.6e-14 52.8 0.0 1.5e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01000974.1_1 - 4.8e-06 26.6 0.0 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AAAP01000974.1_1 - 0.00014 21.8 0.1 0.00024 21.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01000974.1_1 - 0.27 11.6 3.3 0.24 11.7 0.8 2.2 2 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 AAAP01000974.1_1 - 0.57 10.5 2.2 3.3 8.0 1.4 2.5 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit PsiE PF06146.12 AAAP01000975.1_2 - 7e-14 51.9 6.1 8.1e-14 51.8 6.1 1.0 1 0 0 1 1 1 1 Phosphate-starvation-inducible E Pkr1 PF08636.10 AAAP01000975.1_2 - 0.11 12.6 1.4 0.5 10.5 1.3 1.9 2 0 0 2 2 2 0 ER protein Pkr1 GDC-P PF02347.16 AAAP01000976.1_1 - 1.9e-08 33.6 0.4 1.8e-07 30.4 0.2 1.9 2 0 0 2 2 2 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 AAAP01000976.1_1 - 0.00051 19.1 0.2 0.00069 18.7 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01000976.1_1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase LysR_substrate PF03466.20 AAAP01000977.1_2 - 1.6e-29 102.8 2.3 2e-29 102.5 2.3 1.0 1 0 0 1 1 1 1 LysR substrate binding domain PBP_like PF12727.7 AAAP01000977.1_2 - 0.00021 20.5 0.0 0.00021 20.4 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain MOSC PF03473.17 AAAP01000978.1_1 - 6.7e-23 81.1 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 AAAP01000978.1_1 - 6.2e-08 32.4 2.0 1.3e-07 31.3 2.0 1.5 1 0 0 1 1 1 1 3-alpha domain Sigma70_r2 PF04542.14 AAAP01000979.1_2 - 9.1e-17 60.6 0.1 2.3e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 DctM PF06808.12 AAAP01000980.1_1 - 1.6e-39 135.9 22.6 2e-39 135.6 22.6 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component DUF3094 PF11293.8 AAAP01000980.1_1 - 0.085 12.6 0.6 0.085 12.6 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) LapA_dom PF06305.11 AAAP01000980.1_1 - 0.45 10.4 0.0 0.45 10.4 0.0 4.5 4 1 1 5 5 5 0 Lipopolysaccharide assembly protein A domain Otopetrin PF03189.13 AAAP01000980.1_1 - 1.8 7.3 4.4 0.35 9.6 1.2 1.4 2 0 0 2 2 2 0 Otopetrin Hen1_L PF12623.7 AAAP01000982.1_1 - 8.3e-88 293.5 0.0 9.7e-88 293.3 0.0 1.0 1 0 0 1 1 1 1 RNA repair, ligase-Pnkp-associating, region of Hen1 OpuAC PF04069.12 AAAP01000982.1_1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system NUDIX PF00293.28 AAAP01000983.1_1 - 0.085 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain Pro_CA PF00484.19 AAAP01000983.1_2 - 1.2e-18 67.9 0.0 1.4e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase IstB_IS21 PF01695.17 AAAP01000984.1_2 - 2.7e-30 105.4 0.0 3.8e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AAAP01000984.1_2 - 1.5e-05 25.0 0.0 4e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_30 PF13604.6 AAAP01000984.1_2 - 1.9e-05 24.5 0.0 4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 AAAP01000984.1_2 - 1.9e-05 24.2 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AAAP01000984.1_2 - 0.00045 20.6 0.0 0.00079 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 AAAP01000984.1_2 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_28 PF13521.6 AAAP01000984.1_2 - 0.0013 19.0 0.5 0.0039 17.4 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAAP01000984.1_2 - 0.003 17.9 0.8 0.006 16.9 0.6 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01000984.1_2 - 0.0032 16.9 0.2 0.0078 15.6 0.2 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAAP01000984.1_2 - 0.0054 17.0 0.2 0.033 14.5 0.1 2.1 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.9 AAAP01000984.1_2 - 0.0098 15.2 0.2 0.013 14.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 AAAP01000984.1_2 - 0.01 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 AAAP01000984.1_2 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 AAAP01000984.1_2 - 0.028 13.7 0.1 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 AAAP01000984.1_2 - 0.029 13.7 0.1 0.046 13.1 0.0 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.10 AAAP01000984.1_2 - 0.033 13.6 0.0 0.085 12.3 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 ResIII PF04851.15 AAAP01000984.1_2 - 0.033 14.2 0.0 0.057 13.4 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AAAP01000984.1_2 - 0.036 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 AAAP01000984.1_2 - 0.047 12.8 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 AAAP01000984.1_2 - 0.051 13.7 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 AAAP01000984.1_2 - 0.054 13.5 0.7 0.19 11.7 0.4 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AAAP01000984.1_2 - 0.061 13.0 0.1 0.09 12.5 0.1 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 AAAP01000984.1_2 - 0.073 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AAAP01000984.1_2 - 0.074 12.9 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AAAP01000984.1_2 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.21 AAAP01000984.1_2 - 0.082 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 AAAP01000984.1_2 - 0.084 11.9 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.12 AAAP01000984.1_2 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 1 1 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.6 AAAP01000984.1_2 - 0.11 12.7 0.1 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01000984.1_2 - 0.11 12.0 0.7 0.32 10.5 0.1 1.9 1 1 2 3 3 3 0 AAA domain ATPase PF06745.13 AAAP01000984.1_2 - 0.13 11.6 0.1 0.22 10.9 0.0 1.4 2 0 0 2 2 1 0 KaiC UvrD-helicase PF00580.21 AAAP01000985.1_1 - 3.7e-25 89.1 0.0 4.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAAP01000985.1_1 - 2.9e-16 60.1 0.0 4.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AAAP01000985.1_1 - 1.6e-07 31.4 0.0 2.1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Peptidase_M78 PF06114.13 AAAP01000985.1_1 - 0.00041 20.3 0.1 0.0012 18.7 0.1 1.9 1 1 1 2 2 2 1 IrrE N-terminal-like domain AAA_30 PF13604.6 AAAP01000985.1_1 - 0.0005 19.8 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AAAP01000985.1_1 - 0.042 13.8 0.0 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 AAAP01000985.1_1 - 0.11 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.27 AAAP01000986.1_1 - 9.6e-30 103.9 0.0 1.6e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01000986.1_1 - 8.4e-08 31.9 0.0 8.6e-05 22.1 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AAAP01000986.1_1 - 0.0001 21.3 0.9 0.38 9.5 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 AAAP01000986.1_1 - 0.00031 21.0 0.0 0.0012 19.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01000986.1_1 - 0.0004 20.3 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 AAAP01000986.1_1 - 0.00044 19.9 0.7 0.0014 18.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAAP01000986.1_1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01000986.1_1 - 0.0014 18.5 0.1 0.0028 17.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAAP01000986.1_1 - 0.0015 18.3 1.3 0.0041 16.9 1.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01000986.1_1 - 0.0026 18.1 1.8 0.0031 17.9 0.3 1.9 2 1 0 2 2 2 1 AAA ATPase domain Nrap_D3 PF17404.2 AAAP01000986.1_1 - 0.0092 16.1 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 Nrap protein domain 3 AAA PF00004.29 AAAP01000986.1_1 - 0.018 15.4 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAAP01000986.1_1 - 0.024 14.7 0.0 0.054 13.6 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AAAP01000986.1_1 - 0.042 14.1 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAAP01000986.1_1 - 0.062 13.8 0.0 0.097 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01000986.1_1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01000986.1_1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01000986.1_1 - 0.096 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01000986.1_1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 AAAP01000986.1_1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 AAAP01000986.1_1 - 0.82 10.0 3.2 1.8 8.8 0.8 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit EPSP_synthase PF00275.20 AAAP01000987.1_1 - 5.3e-65 219.7 0.9 5.9e-65 219.6 0.9 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) RTC PF01137.21 AAAP01000987.1_1 - 0.065 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase S1 PF00575.23 AAAP01000988.1_1 - 3.9e-20 72.0 0.4 4.6e-20 71.7 0.4 1.1 1 0 0 1 1 1 1 S1 RNA binding domain PCB_OB PF17092.5 AAAP01000988.1_1 - 0.0087 16.8 0.3 0.014 16.1 0.3 1.4 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain Asparaginase_II PF06089.12 AAAP01000989.1_1 - 4.8e-50 170.4 1.9 5.4e-50 170.2 1.9 1.0 1 0 0 1 1 1 1 L-asparaginase II Tyr_Deacylase PF02580.16 AAAP01000989.1_2 - 3.7e-26 92.4 0.3 4.1e-26 92.2 0.3 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase ABC_tran PF00005.27 AAAP01000990.1_2 - 5.6e-27 94.9 0.0 7.1e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01000990.1_2 - 4.8e-05 23.8 0.0 6.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01000990.1_2 - 0.0016 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01000990.1_2 - 0.0022 18.3 0.0 0.0034 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01000990.1_2 - 0.0033 17.0 0.1 0.006 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01000990.1_2 - 0.0057 16.5 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01000990.1_2 - 0.0061 16.5 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 AAAP01000990.1_2 - 0.02 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 AAAP01000990.1_2 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01000990.1_2 - 0.067 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LytB_WW PF18342.1 AAAP01000990.1_2 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain NB-ARC PF00931.22 AAAP01000990.1_2 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 AAAP01000990.1_2 - 0.11 12.3 0.0 0.22 11.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01000990.1_2 - 0.13 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AAAP01000990.1_2 - 0.18 12.2 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 AAAP01000990.1_2 - 0.36 10.5 0.0 0.41 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Phage_lysozyme2 PF18013.1 AAAP01000991.1_1 - 2.4e-18 66.5 0.2 2.9e-18 66.3 0.2 1.1 1 0 0 1 1 1 1 Phage tail lysozyme SLT PF01464.20 AAAP01000991.1_1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Sulfatase PF00884.23 AAAP01000991.1_1 - 0.14 11.5 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Sulfatase Acyl-CoA_dh_1 PF00441.24 AAAP01000992.1_2 - 8.4e-15 55.3 0.9 1.9e-14 54.1 0.9 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01000992.1_2 - 0.047 14.0 0.5 0.047 14.0 0.5 2.2 1 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain SbcD_C PF12320.8 AAAP01000993.1_1 - 2.3e-10 40.6 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain AAA_23 PF13476.6 AAAP01000993.1_2 - 1.7e-14 54.8 0.0 1.7e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01000993.1_2 - 8.4e-08 31.8 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 AAAP01000993.1_2 - 0.00045 19.3 0.0 0.00046 19.3 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AAAP01000993.1_2 - 0.00049 20.6 0.0 0.00061 20.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01000993.1_2 - 0.0006 20.2 0.0 0.00064 20.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 AAAP01000993.1_2 - 0.0017 17.2 0.1 0.002 17.0 0.1 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 AAAP01000993.1_2 - 0.01 15.6 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01000993.1_2 - 0.014 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAAP01000993.1_2 - 0.014 14.5 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein SMC_N PF02463.19 AAAP01000993.1_2 - 0.015 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 AAAP01000993.1_2 - 0.015 14.7 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 AAAP01000993.1_2 - 0.022 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 AAAP01000993.1_2 - 0.022 14.8 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 AAAP01000993.1_2 - 0.029 13.9 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01000993.1_2 - 0.045 13.3 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01000993.1_2 - 0.061 13.2 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 AAAP01000993.1_2 - 0.062 13.2 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 AAAP01000993.1_2 - 0.086 12.6 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01000993.1_2 - 0.09 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 AAAP01000993.1_2 - 0.15 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 AAAP01000993.1_2 - 0.17 12.3 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 AAAP01000993.1_2 - 0.19 11.4 0.0 0.21 11.3 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 AAAP01000993.1_2 - 0.25 11.3 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 AAAP01000993.1_2 - 0.35 10.1 0.0 0.35 10.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HD PF01966.22 AAAP01000994.1_1 - 3.9e-10 40.0 0.4 1.7e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 HD domain HD_5 PF13487.6 AAAP01000994.1_1 - 3.9e-08 33.4 1.5 6.2e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 HD domain Response_reg PF00072.24 AAAP01000994.1_1 - 3.1e-06 27.3 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain PMT PF02366.18 AAAP01000996.1_1 - 1.5e-13 51.0 6.1 1.2e-09 38.1 1.8 2.9 2 1 1 3 3 3 3 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 AAAP01000996.1_1 - 5.1e-13 49.6 0.9 6.8e-13 49.1 0.9 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DAO PF01266.24 AAAP01000997.1_1 - 1e-16 61.5 0.2 1.3e-16 61.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase SBP_bac_5 PF00496.22 AAAP01000998.1_1 - 9.1e-12 44.6 0.3 1.2e-11 44.3 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Fn3-like PF14310.6 AAAP01000998.1_2 - 1.3e-21 76.4 0.6 3.1e-21 75.2 0.6 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4440 PF14534.6 AAAP01000998.1_2 - 0.1 13.0 1.0 0.21 12.0 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) Abhydrolase_3 PF07859.13 AAAP01001000.1_1 - 1e-08 35.3 0.0 1.2e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold FGGY_C PF02782.16 AAAP01001001.1_1 - 7.1e-21 74.8 1.1 9.5e-21 74.4 1.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Glyco_trans_4_4 PF13579.6 AAAP01001001.1_1 - 0.52 10.7 12.4 1.2 9.5 11.8 1.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Aldolase_II PF00596.21 AAAP01001001.1_2 - 2e-12 47.4 0.0 2.4e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain UDG PF03167.19 AAAP01001002.1_1 - 4.3e-07 30.0 0.0 5.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Acatn PF13000.7 AAAP01001003.1_1 - 1.1e-07 30.8 1.0 1.1e-07 30.7 1.0 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 ABC_tran PF00005.27 AAAP01001004.1_1 - 1.5e-27 96.7 0.0 3.2e-27 95.7 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAAP01001004.1_1 - 2.4e-14 53.9 0.0 3.5e-08 33.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01001004.1_1 - 0.0024 17.4 0.1 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01001004.1_1 - 0.011 16.2 0.6 0.025 15.0 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 AAAP01001004.1_1 - 0.016 15.5 0.8 0.85 9.9 0.1 3.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AAAP01001004.1_1 - 0.049 13.4 1.2 0.1 12.4 1.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01001004.1_1 - 0.05 14.1 0.3 0.073 13.6 0.3 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01001004.1_1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01001004.1_1 - 0.14 12.2 0.6 0.63 10.1 0.4 2.3 1 1 1 2 2 2 0 50S ribosome-binding GTPase DUF5010 PF16402.5 AAAP01001004.1_1 - 0.22 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) A_deaminase PF00962.22 AAAP01001005.1_1 - 8.8e-47 160.0 0.0 9.9e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase S1 PF00575.23 AAAP01001008.1_1 - 2.1e-38 130.5 8.7 2.1e-12 47.2 0.0 3.1 3 0 0 3 3 3 3 S1 RNA binding domain S1_2 PF13509.6 AAAP01001008.1_1 - 4.7e-05 23.4 1.5 0.95 9.6 0.7 3.3 3 0 0 3 3 3 2 S1 domain DUF2110 PF09883.9 AAAP01001008.1_1 - 0.002 17.8 3.0 3.1 7.3 0.1 3.1 2 1 0 3 3 3 3 Uncharacterized protein conserved in archaea (DUF2110) PCB_OB PF17092.5 AAAP01001008.1_1 - 0.02 15.6 1.3 2.7 8.8 0.0 3.0 2 1 1 3 3 3 0 Penicillin-binding protein OB-like domain RuvA_N PF01330.21 AAAP01001008.1_1 - 0.27 11.4 1.8 1.4 9.1 0.3 2.4 2 1 0 2 2 2 0 RuvA N terminal domain Peripla_BP_5 PF13433.6 AAAP01001010.1_1 - 7.7e-56 189.6 0.0 9.6e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAAP01001010.1_1 - 9.1e-31 107.8 0.1 1.2e-30 107.4 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01001010.1_1 - 3.9e-05 22.9 0.0 4.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region LPAM_2 PF13627.6 AAAP01001010.1_1 - 0.74 9.7 5.2 1.6 8.7 5.2 1.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site PNTB PF02233.16 AAAP01001011.1_1 - 7.4e-144 480.1 4.6 8.8e-144 479.8 4.6 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AAAP01001011.1_1 - 0.03 14.1 3.5 3.1 7.5 0.0 3.3 3 1 1 4 4 4 0 Thiamine pyrophosphate enzyme, central domain Phage_holin_2_4 PF16082.5 AAAP01001011.1_1 - 0.12 12.2 1.1 0.25 11.1 1.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like FGGY_N PF00370.21 AAAP01001012.1_1 - 5.3e-42 144.1 0.9 5.8e-42 143.9 0.9 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 AAAP01001012.1_2 - 8.8e-11 41.9 0.0 5.6e-05 22.9 0.0 2.0 2 0 0 2 2 2 2 Major intrinsic protein DUF11 PF01345.18 AAAP01001014.1_1 - 0.009 16.3 5.2 0.38 11.1 1.1 3.0 1 1 1 2 2 2 2 Domain of unknown function DUF11 GalBD_like PF17974.1 AAAP01001015.1_1 - 6.8e-27 94.9 0.0 1.1e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 Galactose-binding domain-like HisG_C PF08029.11 AAAP01001015.1_1 - 0.0071 16.5 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain Glyco_hydro_20 PF00728.22 AAAP01001016.1_1 - 1.3e-20 74.1 0.0 1.7e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 AAAP01001016.1_1 - 8.9e-13 49.1 0.0 2.9e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 AAAP01001016.1_1 - 0.00013 22.6 0.0 0.00035 21.2 0.0 1.6 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like polyprenyl_synt PF00348.17 AAAP01001018.1_3 - 1.8e-10 40.3 0.5 2e-10 40.1 0.5 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase polyprenyl_synt PF00348.17 AAAP01001018.1_4 - 0.00055 19.1 0.0 0.00055 19.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Cpn10 PF00166.21 AAAP01001019.1_1 - 2.4e-14 53.1 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cupin_6 PF12852.7 AAAP01001019.1_1 - 0.027 14.2 0.3 0.031 14.0 0.3 1.1 1 0 0 1 1 1 0 Cupin ADH_N PF08240.12 AAAP01001019.1_1 - 0.098 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AhpC-TSA PF00578.21 AAAP01001019.1_2 - 3.4e-11 43.1 0.0 4e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01001019.1_2 - 1.1e-10 41.3 0.1 1.3e-10 41.2 0.1 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 AAAP01001019.1_2 - 0.016 15.1 0.0 0.02 14.8 0.0 1.0 1 0 0 1 1 1 0 SCO1/SenC DDE_Tnp_1_2 PF13586.6 AAAP01001020.1_1 - 6.3e-17 61.7 1.4 7.1e-17 61.6 1.4 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAAP01001020.1_1 - 4.2e-05 23.6 0.2 7.3e-05 22.8 0.1 1.5 1 1 1 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01001020.1_1 - 7.5e-05 22.5 0.3 0.0081 15.8 0.3 2.0 1 1 0 1 1 1 1 Transposase DDE domain HTH_7 PF02796.15 AAAP01001020.1_2 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Resolvase PF00239.21 AAAP01001020.1_2 - 3.7e-06 27.1 1.1 5.7e-06 26.5 0.2 1.7 2 0 0 2 2 2 1 Resolvase, N terminal domain HTH_29 PF13551.6 AAAP01001020.1_2 - 0.00019 21.4 1.4 0.016 15.2 0.1 2.1 2 0 0 2 2 2 2 Winged helix-turn helix HTH_38 PF13936.6 AAAP01001020.1_2 - 0.00022 20.9 0.2 0.00042 20.0 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01001020.1_2 - 0.0021 18.2 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01001020.1_2 - 0.0034 16.8 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AAAP01001020.1_2 - 0.0097 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 AAAP01001020.1_2 - 0.033 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Tc3 transposase CENP-B_N PF04218.13 AAAP01001020.1_2 - 0.064 12.9 0.1 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_5 PF01022.20 AAAP01001021.1_1 - 4.4e-11 42.5 0.0 7.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01001021.1_1 - 4.4e-09 36.3 0.3 7.1e-09 35.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01001021.1_1 - 0.00011 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAAP01001021.1_1 - 0.00078 19.2 0.7 0.0031 17.3 0.4 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAAP01001021.1_1 - 0.0025 17.6 0.4 0.0045 16.8 0.4 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AAAP01001021.1_1 - 0.01 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator CitMHS PF03600.16 AAAP01001021.1_2 - 1.1e-13 51.1 12.5 1.4e-13 50.8 12.5 1.1 1 0 0 1 1 1 1 Citrate transporter GntP_permease PF02447.16 AAAP01001021.1_2 - 0.0031 16.3 5.1 0.0031 16.3 5.1 1.3 1 1 0 1 1 1 1 GntP family permease MatC_N PF07158.11 AAAP01001021.1_2 - 0.0043 17.1 9.8 0.0056 16.7 9.8 1.3 1 0 0 1 1 1 1 Dicarboxylate carrier protein MatC N-terminus ArsB PF02040.15 AAAP01001021.1_2 - 0.0061 15.9 6.5 0.007 15.7 6.5 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein Plug PF07715.15 AAAP01001022.1_1 - 3e-21 76.0 0.4 4.6e-21 75.4 0.4 1.3 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain HAD PF12710.7 AAAP01001023.1_1 - 7.4e-06 26.5 0.1 1.3e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01001023.1_1 - 0.00028 20.7 0.0 0.00034 20.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Iso_dh PF00180.20 AAAP01001024.1_1 - 1.7e-56 191.9 0.0 2e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BKACE PF05853.12 AAAP01001024.1_2 - 5e-22 78.5 1.5 5.6e-22 78.3 1.5 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme BKACE PF05853.12 AAAP01001024.1_3 - 6.6e-06 25.6 0.0 6.8e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme HNH_3 PF13392.6 AAAP01001025.1_1 - 6.6e-05 22.6 1.2 0.00012 21.8 1.2 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 AAAP01001025.1_1 - 0.00037 20.6 5.6 0.00037 20.6 5.6 2.7 3 0 0 3 3 3 1 HNH endonuclease Nudix_N_2 PF14803.6 AAAP01001025.1_1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.7 4 0 0 4 4 4 0 Nudix N-terminal zf_C2H2_13 PF18508.1 AAAP01001025.1_1 - 0.23 11.1 6.4 3.9 7.2 0.2 3.2 3 0 0 3 3 3 0 Zinc finger domain zf-ribbon_3 PF13248.6 AAAP01001025.1_1 - 0.24 10.9 7.0 3 7.4 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain YhfH PF14149.6 AAAP01001025.1_1 - 0.42 10.6 0.4 0.42 10.6 0.4 2.7 3 0 0 3 3 3 0 YhfH-like protein zf-ACC PF17848.1 AAAP01001025.1_1 - 1.3 9.2 0.1 1.3 9.2 0.1 2.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 AAAP01001025.1_1 - 1.8 8.7 11.6 2.6e+02 1.8 11.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon DUF2688 PF10892.8 AAAP01001025.1_1 - 4.2 6.9 9.9 5.9 6.5 1.5 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF2688) Zn-ribbon_8 PF09723.10 AAAP01001025.1_1 - 5 7.3 10.3 1.4 9.1 0.4 3.1 2 1 1 3 3 3 0 Zinc ribbon domain PAS_3 PF08447.12 AAAP01001026.1_1 - 3.2e-38 129.9 0.0 1.2e-20 73.5 0.3 3.2 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAAP01001026.1_1 - 5e-16 58.7 0.0 1.2e-06 28.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AAAP01001026.1_1 - 3.3e-07 30.5 9.0 0.0011 19.2 0.0 3.6 3 1 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AAAP01001026.1_1 - 8.4e-07 28.9 0.1 0.00081 19.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 AAAP01001026.1_1 - 3.7e-06 27.1 0.0 0.066 13.5 0.0 3.1 3 0 0 3 3 3 2 PAS domain Peptidase_M17 PF00883.21 AAAP01001028.1_1 - 1.1e-89 300.9 1.7 1.3e-89 300.6 1.7 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Methyltransf_3 PF01596.17 AAAP01001028.1_2 - 7.7e-16 57.9 0.0 9.1e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 AAAP01001028.1_2 - 0.00095 20.2 0.0 0.0015 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01001028.1_2 - 0.12 13.0 0.0 0.28 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain SBP_bac_6 PF13343.6 AAAP01001031.1_2 - 0.0055 16.2 0.0 0.0055 16.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAAP01001031.1_2 - 0.016 15.0 0.0 0.016 15.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAAP01001031.1_2 - 0.038 13.7 0.0 0.043 13.5 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cys_Met_Meta_PP PF01053.20 AAAP01001032.1_2 - 1.3e-96 323.5 0.0 1.7e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAAP01001032.1_2 - 1.2e-05 24.5 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAAP01001032.1_2 - 2.4e-05 23.8 0.5 4.4e-05 22.9 0.5 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 AAAP01001032.1_2 - 0.011 14.2 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase GDC-P PF02347.16 AAAP01001032.1_2 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein bMG3 PF11974.8 AAAP01001034.1_1 - 2.7e-25 88.4 0.1 2.3e-24 85.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-2-macroglobulin MG3 domain Glyco_hydro_3_C PF01915.22 AAAP01001035.1_1 - 1.4e-39 136.1 0.8 1.7e-39 135.9 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 AAAP01001035.1_1 - 9.1e-10 38.5 0.1 1.9e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4232 PF14016.6 AAAP01001035.1_1 - 0.0083 16.3 14.5 0.015 15.5 1.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF4232) NPCBM_assoc PF10633.9 AAAP01001035.1_1 - 0.17 12.1 4.1 3.4 8.0 0.1 3.2 3 1 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF1467 PF07330.12 AAAP01001036.1_2 - 0.41 10.6 5.1 2.2 8.3 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1467) SLT PF01464.20 AAAP01001037.1_1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Transglycosylase SLT domain F420_ligase PF01996.16 AAAP01001039.1_1 - 0.11 11.9 0.4 0.16 11.3 0.4 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase AA_permease PF00324.21 AAAP01001041.1_1 - 5.5e-14 51.6 10.5 6.3e-14 51.4 10.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAAP01001041.1_1 - 2.9e-09 36.3 9.2 3.8e-09 35.9 9.2 1.2 1 0 0 1 1 1 1 Amino acid permease RseC_MucC PF04246.12 AAAP01001041.1_1 - 1.6 8.7 8.0 6.5 6.7 0.9 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TMEM100 PF16311.5 AAAP01001041.1_2 - 0.0015 18.2 0.3 0.0015 18.2 0.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 100 PGF-CTERM PF18204.1 AAAP01001041.1_2 - 0.0095 15.9 4.4 0.014 15.4 4.4 1.3 1 0 0 1 1 1 1 PGF-CTERM motif PNTB_4TM PF12769.7 AAAP01001042.1_1 - 1.1e-32 112.4 7.0 1.1e-32 112.4 7.0 1.4 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch GH114_assoc PF14741.6 AAAP01001042.1_1 - 0.0011 19.2 0.0 0.0015 18.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal glycosyl-hydrolase-114-associated domain PNTB PF02233.16 AAAP01001042.1_2 - 2.2e-31 109.3 11.7 2.4e-31 109.2 11.7 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit 7TMR-DISM_7TM PF07695.11 AAAP01001042.1_2 - 0.0054 16.7 2.5 0.0073 16.2 2.5 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF456 PF04306.13 AAAP01001042.1_2 - 0.02 15.2 17.4 0.12 12.6 11.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF456) PIG-U PF06728.13 AAAP01001042.1_2 - 0.03 13.4 3.3 0.034 13.2 3.3 1.0 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U YfhO PF09586.10 AAAP01001042.1_2 - 0.071 11.3 2.2 0.086 11.1 2.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF981 PF06168.11 AAAP01001042.1_2 - 0.2 11.5 11.8 0.12 12.3 8.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF981) DUF4131 PF13567.6 AAAP01001042.1_2 - 0.21 11.2 9.6 6.1 6.5 9.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Bax1-I PF01027.20 AAAP01001042.1_2 - 0.65 9.8 13.1 0.65 9.8 9.4 1.9 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 MerC PF03203.14 AAAP01001042.1_2 - 0.81 10.2 10.8 1.3 9.5 10.5 1.4 1 1 1 2 2 2 0 MerC mercury resistance protein LptF_LptG PF03739.14 AAAP01001042.1_2 - 1.7 7.4 7.0 2.7 6.8 7.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF3995 PF13160.6 AAAP01001042.1_2 - 1.8 9.0 21.9 0.096 13.0 9.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF5134 PF17197.4 AAAP01001042.1_2 - 1.9 8.4 15.9 1.5 8.7 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) DUF2892 PF11127.8 AAAP01001042.1_2 - 6.6 6.8 17.6 3.7 7.6 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) DUF2157 PF09925.9 AAAP01001042.1_2 - 7.6 6.3 16.0 3.3 7.5 10.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Bac_luciferase PF00296.20 AAAP01001043.1_1 - 9.8e-42 143.5 5.2 1.2e-41 143.2 5.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 AAAP01001043.1_2 - 3.9e-07 29.8 2.7 6.9e-07 29.0 2.7 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Big_7 PF17957.1 AAAP01001045.1_1 - 1.1e-08 35.6 1.3 1.6e-08 35.2 0.4 1.6 2 0 0 2 2 2 1 Bacterial Ig domain BiPBP_C PF06832.12 AAAP01001045.1_1 - 0.00057 19.9 0.9 0.0013 18.7 0.9 1.9 1 1 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family RHS_repeat PF05593.14 AAAP01001045.1_1 - 0.0052 17.3 2.1 0.01 16.3 2.1 1.5 1 0 0 1 1 1 1 RHS Repeat CBM_6 PF03422.15 AAAP01001045.1_1 - 0.0067 16.7 0.2 0.0092 16.3 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) PKD PF00801.20 AAAP01001045.1_1 - 0.025 14.4 0.8 0.093 12.6 0.1 2.2 1 1 1 2 2 2 0 PKD domain Pollen_allerg_1 PF01357.21 AAAP01001045.1_1 - 0.062 13.3 0.5 0.13 12.3 0.3 1.6 1 1 1 2 2 2 0 Pollen allergen Haem_degrading PF03928.14 AAAP01001046.1_1 - 7.7e-34 116.3 0.0 9.2e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading ADP_ribosyl_GH PF03747.14 AAAP01001046.1_2 - 2.1e-09 37.5 0.2 2.4e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase OEP PF02321.18 AAAP01001049.1_1 - 5.3e-16 59.0 17.3 1.1e-10 41.7 15.0 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DUF1223 PF06764.11 AAAP01001049.1_1 - 0.0095 16.0 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) CdvA PF18822.1 AAAP01001049.1_1 - 0.1 12.4 1.1 2.6 7.9 0.9 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain CPBP PF02517.16 AAAP01001050.1_1 - 0.13 12.6 0.2 0.13 12.6 0.2 1.4 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease 2-Hacid_dh_C PF02826.19 AAAP01001051.1_1 - 1.1e-25 90.0 0.0 1.6e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01001051.1_1 - 2.1e-20 72.7 0.0 2.4e-20 72.6 0.0 1.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 AAAP01001051.1_1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LCIB_C_CA PF18599.1 AAAP01001051.1_1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CbtA PF09490.10 AAAP01001052.1_1 - 2.1e-13 50.6 1.3 2.1e-13 50.6 1.3 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) CbtB PF09489.10 AAAP01001052.1_3 - 1.7e-21 76.0 4.5 2e-21 75.8 4.5 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) Anophelin PF10731.9 AAAP01001052.1_3 - 0.11 12.4 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito adh_short_C2 PF13561.6 AAAP01001054.1_2 - 1.9e-32 112.7 0.2 2.4e-32 112.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001054.1_2 - 7.6e-22 77.7 0.0 1.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAAP01001054.1_2 - 0.00092 18.7 0.0 0.0062 16.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAAP01001054.1_2 - 0.0038 17.2 0.1 0.0054 16.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Lipase_GDSL_2 PF13472.6 AAAP01001055.1_1 - 2.7e-06 27.9 0.0 4.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3333 PF11812.8 AAAP01001055.1_1 - 0.043 14.0 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Glyco_hydro_19 PF00182.19 AAAP01001056.1_2 - 3.7e-13 49.9 0.1 4.2e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Chitinase class I Tim44 PF04280.15 AAAP01001057.1_1 - 2.7e-21 76.2 0.0 3.2e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Tim44-like domain Hepar_II_III PF07940.13 AAAP01001058.1_1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Heparinase II/III-like protein TonB_dep_Rec PF00593.24 AAAP01001059.1_1 - 0.026 14.4 4.2 0.032 14.1 4.2 1.2 1 0 0 1 1 1 0 TonB dependent receptor BBP2_2 PF10082.9 AAAP01001059.1_1 - 0.041 12.7 0.2 0.063 12.1 0.2 1.2 1 0 0 1 1 1 0 Putative beta-barrel porin 2 DUF3851 PF12962.7 AAAP01001060.1_1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Flg_bbr_C PF06429.13 AAAP01001060.1_2 - 1.5e-13 50.7 0.2 4.5e-13 49.1 0.2 1.8 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01001060.1_2 - 1.5e-07 31.2 1.2 3.6e-07 30.0 1.2 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein Lactamase_B PF00753.27 AAAP01001061.1_1 - 8.7e-12 45.5 3.3 1.7e-11 44.5 3.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01001061.1_1 - 1.4e-07 31.2 2.9 5.4e-07 29.3 2.5 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAAP01001061.1_1 - 0.0025 17.7 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_S24 PF00717.23 AAAP01001062.1_2 - 9.9e-20 70.3 0.0 5.1e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 AAAP01001062.1_2 - 5.6e-09 35.9 0.5 0.0016 18.2 0.1 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 IMS_C PF11799.8 AAAP01001063.1_1 - 5.1e-23 82.0 0.3 8.6e-23 81.3 0.2 1.3 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain Bro-N PF02498.17 AAAP01001064.1_1 - 1.5e-12 48.0 0.0 2.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 BRO family, N-terminal domain Epimerase PF01370.21 AAAP01001065.1_1 - 1.7e-15 57.1 0.0 2e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NMO PF03060.15 AAAP01001067.1_1 - 9.2e-43 146.9 1.2 1.1e-42 146.6 1.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 AAAP01001067.1_1 - 2.7e-06 26.6 0.7 3.7e-06 26.2 0.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AAAP01001067.1_1 - 4e-06 26.1 3.2 4.8e-06 25.8 3.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAAP01001067.1_1 - 5.5e-06 26.0 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF561 PF04481.12 AAAP01001067.1_1 - 0.00047 19.4 0.2 0.00061 19.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF561) DHO_dh PF01180.21 AAAP01001067.1_1 - 0.0023 17.2 0.5 0.003 16.8 0.5 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 AAAP01001067.1_1 - 0.0024 17.2 3.7 0.0061 15.9 3.4 1.8 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 AAAP01001067.1_1 - 0.032 13.4 0.2 0.052 12.7 0.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 AAAP01001067.1_1 - 0.033 13.6 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 AAAP01001067.1_1 - 0.035 13.2 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) NanE PF04131.14 AAAP01001067.1_1 - 0.04 13.1 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 AAAP01001067.1_1 - 0.14 11.5 0.8 0.2 11.0 0.8 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase SSF PF00474.17 AAAP01001068.1_1 - 1.8e-47 162.2 12.6 2.2e-47 161.8 12.6 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 AAAP01001068.1_1 - 0.069 13.7 0.2 0.069 13.7 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2818) adh_short PF00106.25 AAAP01001069.1_1 - 4.4e-19 68.7 3.4 4.9e-19 68.6 3.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01001069.1_1 - 1.9e-12 47.3 4.8 2.1e-12 47.1 4.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 AAAP01001069.1_1 - 4.6e-05 23.0 1.0 5e-05 22.9 1.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 AAAP01001069.1_1 - 0.00021 21.3 3.0 0.00026 21.0 3.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 AAAP01001069.1_1 - 0.00033 20.6 1.6 0.00038 20.4 1.6 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 AAAP01001069.1_1 - 0.009 15.1 0.5 0.0099 14.9 0.5 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AAAP01001069.1_1 - 0.021 14.3 0.1 0.024 14.0 0.1 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 AAAP01001069.1_1 - 0.024 14.0 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AAAP01001069.1_1 - 0.03 14.2 6.2 0.038 13.9 6.2 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 AAAP01001069.1_1 - 0.04 14.2 1.3 0.05 13.9 1.3 1.2 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 AAAP01001069.1_1 - 0.12 11.5 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HHH_5 PF14520.6 AAAP01001069.1_1 - 0.13 12.9 1.7 4.8 7.9 0.2 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain 3HCDH_N PF02737.18 AAAP01001069.1_1 - 0.32 10.9 2.4 0.37 10.6 2.4 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAAP01001069.1_1 - 0.8 9.8 4.9 1.5 8.9 4.0 1.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PfkB PF00294.24 AAAP01001070.1_1 - 4.9e-06 26.1 0.8 5.7e-06 25.9 0.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PadR PF03551.14 AAAP01001071.1_2 - 3e-17 62.3 0.0 4.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TrmB PF01978.19 AAAP01001071.1_2 - 0.031 14.2 0.1 0.28 11.1 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB AIG2_2 PF13772.6 AAAP01001072.1_1 - 1.8e-14 53.9 0.0 2.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 AAAP01001072.1_1 - 5.6e-10 39.9 0.0 6.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Form_Nir_trans PF01226.17 AAAP01001072.1_2 - 2.3e-10 40.2 3.2 2.6e-10 40.1 3.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter PepSY PF03413.19 AAAP01001075.1_1 - 7.6e-05 23.2 1.8 0.00015 22.3 1.8 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Phyto-Amp PF15438.6 AAAP01001075.1_1 - 0.0028 17.5 0.7 0.0035 17.2 0.7 1.2 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma PepSY_2 PF13670.6 AAAP01001075.1_1 - 2.4 8.2 9.7 4.4 7.4 3.5 2.5 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain MinE PF03776.14 AAAP01001075.1_2 - 2.2e-20 72.4 0.0 2.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE Hemocyanin_M PF00372.19 AAAP01001075.1_2 - 0.043 13.0 0.0 0.045 12.9 0.0 1.0 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Pectate_lyase_2 PF06917.12 AAAP01001076.1_1 - 1.1e-28 100.1 0.0 1.2e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Periplasmic pectate lyase HisKA PF00512.25 AAAP01001077.1_1 - 1.5e-26 92.2 4.8 8.6e-23 80.2 0.0 3.4 1 1 2 3 3 3 3 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01001077.1_1 - 1.5e-12 47.7 0.3 3.1e-12 46.7 0.3 1.6 1 0 0 1 1 1 1 HAMP domain Apolipoprotein PF01442.18 AAAP01001077.1_1 - 0.026 14.4 3.0 0.038 13.9 3.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 AAAP01001077.1_1 - 0.067 13.2 2.3 0.073 13.1 0.8 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 AAAP01001077.1_1 - 0.16 12.5 1.0 0.41 11.2 1.0 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal MukF_M PF17192.4 AAAP01001077.1_1 - 0.17 11.6 3.7 1.6 8.5 1.0 2.2 2 0 0 2 2 2 0 MukF middle domain TetR_C_16 PF17920.1 AAAP01001079.1_1 - 0.16 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Mad3_BUB1_II PF08171.11 AAAP01001080.1_1 - 0.14 12.4 0.0 0.7 10.1 0.0 1.9 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 OEP PF02321.18 AAAP01001080.1_2 - 1.9e-07 31.1 2.5 2.4e-07 30.8 2.5 1.1 1 0 0 1 1 1 1 Outer membrane efflux protein Vut_1 PF02592.15 AAAP01001082.1_1 - 1.5e-41 142.2 4.9 2.5e-41 141.5 4.9 1.2 1 0 0 1 1 1 1 Putative vitamin uptake transporter DoxX PF07681.12 AAAP01001083.1_1 - 2.2e-08 34.6 2.1 4.5e-08 33.6 2.1 1.5 1 0 0 1 1 1 1 DoxX DUF1275 PF06912.11 AAAP01001084.1_1 - 4.2e-22 79.0 15.1 4.7e-22 78.8 15.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) NB-ARC PF00931.22 AAAP01001087.1_1 - 6e-06 25.6 0.0 8.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Glyco_hydro_3 PF00933.21 AAAP01001090.1_1 - 7e-07 28.9 0.0 7.8e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain GATase_6 PF13522.6 AAAP01001090.1_1 - 0.093 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase domain Bac_luciferase PF00296.20 AAAP01001091.1_1 - 6.5e-14 52.1 1.7 7.5e-14 51.9 1.7 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CysA_C_terminal PF17850.1 AAAP01001091.1_1 - 0.013 16.1 0.1 0.037 14.6 0.0 1.9 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Aminotran_3 PF00202.21 AAAP01001093.1_2 - 1.6e-13 50.1 0.0 1.7e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PTR2 PF00854.21 AAAP01001095.1_1 - 3.4e-21 75.6 2.9 3.4e-21 75.6 2.9 1.4 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 AAAP01001095.1_1 - 5.5e-07 28.8 13.3 7.6e-07 28.4 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01001095.1_1 - 0.0022 16.9 7.1 0.0028 16.6 7.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter COX8 PF02285.15 AAAP01001095.1_1 - 0.024 14.5 6.7 0.76 9.7 0.1 3.6 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII NAD_kinase PF01513.21 AAAP01001096.1_1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase ABC_membrane PF00664.23 AAAP01001096.1_2 - 1.9e-05 24.4 0.0 2.2e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Formyl_trans_C PF02911.18 AAAP01001097.1_1 - 4.7e-17 62.1 0.0 6.1e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PGM1_C PF18105.1 AAAP01001097.1_1 - 0.0018 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 PGM1 C-terminal domain Abhydrolase_6 PF12697.7 AAAP01001098.1_1 - 5.4e-17 63.1 10.3 7.7e-17 62.6 10.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01001098.1_1 - 9.1e-08 31.7 0.5 1.4e-07 31.0 0.5 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01001098.1_1 - 1.2e-06 28.4 0.1 2e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AAAP01001098.1_1 - 0.0073 16.0 0.1 0.017 14.8 0.1 1.6 1 1 1 2 2 2 1 Putative esterase Glyco_hydro_35 PF01301.19 AAAP01001098.1_1 - 0.052 13.2 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Abhydrolase_2 PF02230.16 AAAP01001098.1_1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 AAAP01001098.1_1 - 0.25 11.3 0.0 0.31 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAS_4 PF08448.10 AAAP01001099.1_1 - 4.7e-14 52.6 0.3 7.3e-14 52.0 0.3 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01001099.1_1 - 0.00021 21.3 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01001099.1_1 - 0.074 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 PAS domain SBP_bac_5 PF00496.22 AAAP01001100.1_1 - 7e-30 104.2 1.5 1e-29 103.7 1.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle FmdA_AmdA PF03069.15 AAAP01001101.1_1 - 1.2e-17 63.9 0.0 1.4e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family AMP-binding PF00501.28 AAAP01001102.1_1 - 2.8e-37 128.3 0.2 3.8e-37 127.9 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BAT PF15915.5 AAAP01001102.1_1 - 0.0046 16.9 0.9 0.007 16.2 0.9 1.3 1 0 0 1 1 1 1 GAF and HTH_10 associated domain AMP-binding_C PF13193.6 AAAP01001102.1_1 - 0.017 16.1 0.2 0.027 15.4 0.2 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PQQ PF01011.21 AAAP01001103.1_1 - 6.4e-07 29.0 6.1 0.016 15.1 0.0 3.9 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 AAAP01001103.1_1 - 0.00044 19.9 2.0 1.7 8.1 0.6 3.3 3 1 0 3 3 3 2 PQQ-like domain Phage_Mu_F PF04233.14 AAAP01001104.1_1 - 0.00077 20.2 0.5 0.0011 19.6 0.5 1.3 1 0 0 1 1 1 1 Phage Mu protein F like protein TF_AP-2 PF03299.14 AAAP01001104.1_1 - 0.11 12.5 0.1 0.11 12.4 0.1 1.0 1 0 0 1 1 1 0 Transcription factor AP-2 FecCD PF01032.18 AAAP01001105.1_1 - 1.3e-47 162.4 23.2 1.7e-47 161.9 23.2 1.1 1 0 0 1 1 1 1 FecCD transport family Neisseria_PilC PF05567.11 AAAP01001106.1_1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain PhzC-PhzF PF02567.16 AAAP01001107.1_2 - 7.5e-14 51.9 0.1 8.8e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Na_H_Exchanger PF00999.21 AAAP01001108.1_1 - 4e-26 91.7 16.7 5.5e-26 91.3 16.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AAAP01001108.1_1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain MFS_1 PF07690.16 AAAP01001109.1_1 - 4.5e-12 45.6 23.4 1.8e-07 30.4 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01001109.1_1 - 1.8 7.3 9.0 2.3 7.0 9.0 1.0 1 0 0 1 1 1 0 MFS_1 like family OprB PF04966.12 AAAP01001110.1_1 - 2.3e-05 24.0 0.0 2.6e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family LysR_substrate PF03466.20 AAAP01001111.1_1 - 0.036 13.4 0.1 0.036 13.4 0.1 1.0 1 0 0 1 1 1 0 LysR substrate binding domain adh_short_C2 PF13561.6 AAAP01001111.1_2 - 2.1e-36 125.7 0.5 2.3e-36 125.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001111.1_2 - 4.4e-23 81.8 0.3 6.4e-23 81.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase MurJ PF03023.14 AAAP01001112.1_1 - 1.5e-22 79.8 4.4 2.3e-22 79.2 4.4 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ MatE PF01554.18 AAAP01001112.1_1 - 0.0031 17.2 9.8 0.005 16.5 9.3 1.8 1 1 0 1 1 1 1 MatE DUF983 PF06170.12 AAAP01001113.1_2 - 5.3e-14 52.4 4.4 6.2e-14 52.2 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF983) GARP PF16731.5 AAAP01001114.1_1 - 0.029 14.0 9.7 0.034 13.8 9.7 1.1 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF2524 PF10732.9 AAAP01001114.1_1 - 0.062 13.6 0.2 0.091 13.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DUF1816 PF08846.10 AAAP01001114.1_1 - 0.065 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) PAP2 PF01569.21 AAAP01001114.1_2 - 6.2e-05 22.8 0.5 0.0001 22.1 0.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily ACR_tran PF00873.19 AAAP01001115.1_1 - 1.4e-49 168.7 0.4 1.6e-49 168.5 0.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01001115.1_1 - 9.5e-13 47.8 5.2 1.2e-12 47.4 5.2 1.1 1 0 0 1 1 1 1 MMPL family SecD_SecF PF02355.16 AAAP01001115.1_1 - 0.00048 19.6 1.5 0.00057 19.3 1.5 1.1 1 0 0 1 1 1 1 Protein export membrane protein DUF983 PF06170.12 AAAP01001115.1_1 - 0.27 11.7 2.2 0.6 10.5 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Patched PF02460.18 AAAP01001115.1_1 - 1.1 7.3 3.9 2.2 6.2 3.9 1.5 1 1 0 1 1 1 0 Patched family ACR_tran PF00873.19 AAAP01001115.1_2 - 1.3e-16 59.6 0.1 1.4e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family K_channel_TID PF07941.11 AAAP01001116.1_1 - 0.098 13.1 0.5 0.098 13.1 0.5 1.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Glyoxalase PF00903.25 AAAP01001116.1_2 - 0.00032 20.9 0.0 0.00038 20.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F5_F8_type_C PF00754.25 AAAP01001117.1_2 - 2.4e-09 37.4 0.0 3.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Pox_A31 PF05771.11 AAAP01001119.1_1 - 0.087 12.8 0.3 0.1 12.6 0.3 1.1 1 0 0 1 1 1 0 Poxvirus A31 protein Bac_luciferase PF00296.20 AAAP01001120.1_1 - 2.8e-25 89.4 0.2 3.5e-25 89.1 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase GATase_6 PF13522.6 AAAP01001121.1_1 - 0.0017 18.5 0.3 0.0026 18.0 0.3 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAAP01001121.1_1 - 0.075 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Hexapep_2 PF14602.6 AAAP01001121.1_2 - 0.0063 16.2 0.4 0.0085 15.8 0.4 1.1 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AAAP01001121.1_2 - 0.017 14.8 0.3 0.022 14.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) MdoG PF04349.12 AAAP01001122.1_1 - 1.2e-36 126.8 0.0 1.3e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG MdoG PF04349.12 AAAP01001122.1_2 - 1.9e-67 228.2 0.0 2.3e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG Proton_antipo_M PF00361.20 AAAP01001123.1_2 - 3e-10 39.8 1.0 4.8e-10 39.1 1.0 1.3 1 0 0 1 1 1 1 Proton-conducting membrane transporter Phage_holin_3_6 PF07332.11 AAAP01001123.1_2 - 4.6 7.3 25.0 0.12 12.4 9.8 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III GntR PF00392.21 AAAP01001124.1_1 - 3.4e-18 65.0 0.3 2.5e-17 62.3 0.1 2.0 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAAP01001124.1_1 - 0.00011 22.0 0.5 0.00033 20.5 0.2 1.9 2 1 0 2 2 2 1 MarR family HTH_36 PF13730.6 AAAP01001124.1_1 - 0.00043 20.2 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 AAAP01001124.1_1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AAAP01001124.1_1 - 0.0055 17.0 0.0 0.0092 16.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 AAAP01001124.1_1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 HTH domain LexA_DNA_bind PF01726.16 AAAP01001124.1_1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 1 0 1 1 1 0 LexA DNA binding domain Fe_dep_repress PF01325.19 AAAP01001124.1_1 - 0.02 15.1 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_50 PF18024.1 AAAP01001124.1_1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_41 PF14502.6 AAAP01001124.1_1 - 0.037 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01001124.1_1 - 0.045 13.8 0.1 0.25 11.4 0.1 2.0 1 1 1 2 2 2 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 AAAP01001124.1_1 - 0.064 12.7 0.3 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 AAAP01001124.1_1 - 0.1 12.4 0.0 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 AAAP01001124.1_1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Acid_phosphat_B PF03767.14 AAAP01001125.1_1 - 0.11 12.1 0.6 0.12 11.9 0.6 1.0 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PHO4 PF01384.20 AAAP01001125.1_2 - 4.1e-31 108.3 12.4 5.2e-31 107.9 12.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family SBP_bac_3 PF00497.20 AAAP01001128.1_2 - 2.2e-22 79.6 0.1 2.3e-22 79.6 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAAP01001128.1_2 - 0.00096 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Aldo_ket_red PF00248.21 AAAP01001129.1_1 - 4.4e-14 52.4 0.0 5.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.25 AAAP01001129.1_2 - 5.6e-05 23.4 0.0 5.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01001129.1_2 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PfkB PF00294.24 AAAP01001130.1_1 - 5.7e-54 183.5 8.8 6.4e-54 183.3 8.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AAAP01001130.1_1 - 2.7e-05 23.7 0.2 3.8e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase tRNA_anti-codon PF01336.25 AAAP01001131.1_1 - 2.6e-15 56.1 0.0 5.5e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain GerE PF00196.19 AAAP01001132.1_1 - 4.2e-21 74.2 0.1 6.2e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAAP01001132.1_1 - 3.1e-18 66.0 0.0 5.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAAP01001132.1_1 - 1.7e-10 40.4 0.1 1.3e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01001132.1_1 - 2.7e-06 26.8 0.1 6.2e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AAAP01001132.1_1 - 0.00059 19.3 0.1 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AAAP01001132.1_1 - 0.012 15.5 0.1 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 ECF sigma factor QRPTase_C PF01729.19 AAAP01001132.1_1 - 0.079 12.7 0.3 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain HTH_40 PF14493.6 AAAP01001132.1_1 - 0.2 12.2 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 AAAP01001132.1_1 - 0.31 10.9 0.8 3.4 7.6 0.0 2.5 3 0 0 3 3 3 0 HTH DNA binding domain SHOCT PF09851.9 AAAP01001132.1_2 - 4.2e-08 32.7 0.0 6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Short C-terminal domain VbhA PF18495.1 AAAP01001132.1_2 - 0.00057 19.7 0.5 0.0022 17.8 0.1 2.0 2 0 0 2 2 2 1 Antitoxin VbhA DUF1707 PF08044.11 AAAP01001132.1_2 - 0.0086 16.1 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) CdvA PF18822.1 AAAP01001132.1_2 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Phytase-like PF13449.6 AAAP01001133.1_1 - 8.7e-37 127.6 0.3 1.2e-36 127.2 0.3 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase DciA PF05258.12 AAAP01001134.1_1 - 1.9e-24 85.9 0.2 3e-24 85.2 0.2 1.3 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA MFS_1 PF07690.16 AAAP01001137.1_1 - 1.3e-14 53.9 9.9 1.8e-14 53.4 9.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 AAAP01001137.1_1 - 1.1e-09 37.3 8.5 1.3e-09 37.0 8.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Fumarate_red_D PF02313.17 AAAP01001137.1_1 - 0.057 13.5 0.2 0.057 13.5 0.2 2.7 3 0 0 3 3 3 0 Fumarate reductase subunit D ABC_tran PF00005.27 AAAP01001138.1_1 - 7.1e-19 68.7 0.0 8e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01001138.1_1 - 0.0001 22.8 0.1 0.00012 22.5 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01001138.1_1 - 0.00068 19.5 0.0 0.00082 19.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01001138.1_1 - 0.002 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAAP01001138.1_1 - 0.012 16.2 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01001138.1_1 - 0.027 14.9 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAAP01001138.1_1 - 0.047 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01001138.1_1 - 0.053 13.8 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AAAP01001138.1_1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AAAP01001138.1_1 - 0.074 12.6 0.2 0.16 11.6 0.1 1.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAAP01001138.1_1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 AAAP01001138.1_1 - 0.11 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AAAP01001138.1_1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01001138.1_1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 AAAP01001138.1_1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 AAAP01001138.1_1 - 0.19 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3584 PF12128.8 AAAP01001138.1_1 - 0.2 9.1 0.3 0.24 8.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 AAAP01001138.1_1 - 0.37 9.4 0.0 0.39 9.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain DUF2141 PF09912.9 AAAP01001138.1_2 - 1.8e-16 60.1 0.0 1.9e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) MMPL PF03176.15 AAAP01001140.1_1 - 5.6e-08 32.1 10.3 1.1e-07 31.1 10.3 1.5 1 1 0 1 1 1 1 MMPL family MFS_2 PF13347.6 AAAP01001142.1_1 - 0.00057 18.6 5.7 0.00093 17.9 5.7 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein LRV PF01816.17 AAAP01001142.1_1 - 0.0093 16.3 0.2 0.035 14.5 0.2 2.1 1 0 0 1 1 1 1 Leucine rich repeat variant MFS_3 PF05977.13 AAAP01001142.1_1 - 0.7 8.2 14.3 3.2 6.0 14.3 1.9 1 1 0 1 1 1 0 Transmembrane secretion effector HlyD_3 PF13437.6 AAAP01001143.1_1 - 6.2e-06 26.9 0.3 1.6e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01001143.1_1 - 5.4e-05 22.5 1.2 8.1e-05 21.9 1.2 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Phage_holin_7_1 PF16081.5 AAAP01001143.1_1 - 0.023 14.9 3.4 0.038 14.2 3.4 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DRY_EERY PF09750.9 AAAP01001143.1_1 - 0.068 13.4 0.8 0.081 13.2 0.8 1.2 1 0 0 1 1 1 0 Alternative splicing regulator Biotin_lipoyl_2 PF13533.6 AAAP01001143.1_1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 Biotin-lipoyl like PilO PF04350.13 AAAP01001143.1_1 - 0.23 11.6 1.3 0.33 11.1 1.3 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF3584 PF12128.8 AAAP01001143.1_1 - 1.3 6.4 7.9 1.5 6.2 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OEP PF02321.18 AAAP01001143.1_1 - 1.4 8.7 12.5 8.1 6.2 7.0 2.0 1 1 1 2 2 2 0 Outer membrane efflux protein ParE_toxin PF05016.15 AAAP01001144.1_1 - 0.0077 16.8 0.1 0.0096 16.5 0.1 1.2 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE PhdYeFM_antitox PF02604.19 AAAP01001144.1_2 - 3.2e-20 71.7 0.1 3.5e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AAAP01001144.1_2 - 0.0056 16.7 0.0 0.0056 16.7 0.0 1.1 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Astro_capsid_N PF03115.14 AAAP01001144.1_2 - 0.12 11.0 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF5516 PF17637.2 AAAP01001145.1_1 - 0.052 13.3 0.7 0.062 13.1 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5516) ABC2_membrane_3 PF12698.7 AAAP01001146.1_1 - 0.001 18.3 6.4 0.0011 18.1 6.4 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAAP01001146.1_1 - 0.0016 17.9 0.8 0.0016 17.9 0.8 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AAAP01001146.1_1 - 0.0029 16.9 0.6 0.0035 16.7 0.6 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein HAD_2 PF13419.6 AAAP01001147.1_1 - 3.1e-06 27.4 0.0 3.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01001147.1_1 - 0.005 17.1 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01001147.1_1 - 0.11 12.9 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NT5C PF06941.12 AAAP01001147.1_1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Ribul_P_3_epim PF00834.19 AAAP01001147.1_2 - 2.8e-39 134.6 0.0 3.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family LRV PF01816.17 AAAP01001147.1_2 - 0.017 15.5 0.2 0.042 14.2 0.2 1.7 1 0 0 1 1 1 0 Leucine rich repeat variant DHO_dh PF01180.21 AAAP01001147.1_2 - 0.046 12.9 0.4 0.058 12.6 0.4 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PseudoU_synth_2 PF00849.22 AAAP01001148.1_1 - 9.1e-31 107.1 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAAP01001148.1_1 - 1.2e-07 31.3 0.6 2.6e-07 30.3 0.2 1.7 2 0 0 2 2 2 1 S4 domain NP1-WLL PF11733.8 AAAP01001148.1_1 - 0.23 11.2 1.1 0.34 10.6 1.1 1.2 1 0 0 1 1 1 0 Non-capsid protein NP1 BPD_transp_2 PF02653.16 AAAP01001149.1_2 - 5.8e-22 78.1 20.8 7.2e-22 77.8 20.8 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component MotA_ExbB PF01618.16 AAAP01001149.1_2 - 3.7 7.3 9.2 6.5 6.5 9.2 1.4 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Cellsynth_D PF03500.13 AAAP01001150.1_1 - 0.12 12.2 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Cellulose synthase subunit D 5_nucleotid_C PF02872.18 AAAP01001151.1_1 - 0.00024 21.3 0.0 0.00024 21.3 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Putative_PNPOx PF01243.20 AAAP01001152.1_1 - 9.6e-06 25.7 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PDGLE PF13190.6 AAAP01001153.1_1 - 0.031 14.2 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 PDGLE domain TPR_17 PF13431.6 AAAP01001153.1_2 - 0.00031 20.9 0.1 0.00065 19.9 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01001153.1_2 - 0.0038 17.9 0.4 0.0038 17.9 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01001153.1_2 - 0.0044 17.5 2.2 0.007 16.9 2.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01001153.1_2 - 0.0058 16.6 6.8 0.015 15.4 6.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01001153.1_2 - 0.016 15.4 0.7 0.042 14.1 0.8 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01001153.1_2 - 0.15 11.8 0.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 AAAP01001153.1_2 - 0.15 12.0 2.7 0.31 10.9 2.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01001153.1_2 - 0.58 10.9 7.5 0.24 12.1 4.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DapB_C PF05173.14 AAAP01001153.1_3 - 2.2e-11 43.9 0.0 2.4e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Potex_coat PF06184.11 AAAP01001153.1_3 - 0.024 14.2 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Potexvirus coat protein adh_short_C2 PF13561.6 AAAP01001154.1_1 - 5.9e-49 166.7 0.0 6.6e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001154.1_1 - 4.4e-31 107.9 0.0 5.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase GerE PF00196.19 AAAP01001154.1_2 - 3.5e-12 45.7 0.0 3.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AAAP01001154.1_2 - 0.0014 18.4 0.1 0.003 17.3 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_10 PF04967.12 AAAP01001154.1_2 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.5 1 1 0 1 1 1 1 HTH DNA binding domain HTH_28 PF13518.6 AAAP01001154.1_2 - 0.0019 18.3 0.1 0.0072 16.4 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01001154.1_2 - 0.003 17.3 0.2 0.0069 16.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01001154.1_2 - 0.0098 15.4 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 AAAP01001154.1_2 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 Sigma-70, region 4 DUF2089 PF09862.9 AAAP01001154.1_2 - 0.031 14.3 0.0 0.033 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_11 PF08279.12 AAAP01001154.1_2 - 0.083 12.8 0.0 0.22 11.5 0.0 1.7 1 1 1 2 2 2 0 HTH domain HTH_5 PF01022.20 AAAP01001154.1_2 - 0.13 12.2 0.0 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_40 PF14493.6 AAAP01001154.1_2 - 0.13 12.7 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L18p PF00861.22 AAAP01001155.1_1 - 6.2e-29 100.7 2.3 7.5e-29 100.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast MMR_HSR1 PF01926.23 AAAP01001156.1_1 - 1.2e-26 93.1 0.0 1.3e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01001156.1_1 - 1.3e-11 44.2 0.0 2.3e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AAAP01001156.1_1 - 3.7e-07 29.9 0.0 0.00073 19.1 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AAAP01001156.1_1 - 1.2e-06 28.7 0.0 0.0052 16.8 0.0 2.1 2 0 0 2 2 2 2 Dynamin family Roc PF08477.13 AAAP01001156.1_1 - 7.6e-05 22.9 0.0 0.00031 21.0 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 AAAP01001156.1_1 - 8.4e-05 22.2 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Ras family AIG1 PF04548.16 AAAP01001156.1_1 - 0.00027 20.3 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 AAAP01001156.1_1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 AAAP01001156.1_1 - 0.053 13.0 0.0 0.085 12.3 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 AAAP01001156.1_1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01001156.1_1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.12 AAAP01001156.1_1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_24 PF13479.6 AAAP01001156.1_1 - 0.16 11.6 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rdx PF10262.9 AAAP01001159.1_1 - 2.2e-27 95.0 0.0 2.5e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Rdx family tRNA_NucTran2_2 PF13735.6 AAAP01001160.1_1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF465 PF04325.13 AAAP01001160.1_1 - 0.076 13.1 1.0 0.15 12.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) MFS_1 PF07690.16 AAAP01001162.1_1 - 8.5e-18 64.4 46.5 4.1e-17 62.1 39.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 AAAP01001162.1_1 - 0.02 13.4 0.6 0.079 11.5 0.3 1.9 1 1 1 2 2 2 0 Acetyl-coenzyme A transporter 1 BT1 PF03092.16 AAAP01001162.1_1 - 0.046 12.0 10.6 0.079 11.2 1.7 2.2 2 0 0 2 2 2 0 BT1 family MFS_1_like PF12832.7 AAAP01001162.1_1 - 9.6 4.9 17.3 1.1 8.1 13.1 1.6 1 1 1 2 2 2 0 MFS_1 like family DUF2570 PF10828.8 AAAP01001163.1_1 - 0.0046 16.8 0.8 0.0059 16.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Tektin PF03148.14 AAAP01001163.1_1 - 0.021 13.6 0.2 0.023 13.5 0.2 1.0 1 0 0 1 1 1 0 Tektin family Topoisom_I PF01028.20 AAAP01001163.1_1 - 0.068 12.4 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core DUF1664 PF07889.12 AAAP01001163.1_1 - 0.1 12.6 0.3 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MNHE PF01899.16 AAAP01001164.1_1 - 7.1e-32 110.2 3.9 8e-32 110.0 3.9 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit MrpF_PhaF PF04066.13 AAAP01001164.1_2 - 0.0031 17.9 1.2 0.0031 17.9 1.2 2.1 2 0 0 2 2 2 2 Multiple resistance and pH regulation protein F (MrpF / PhaF) CBS PF00571.28 AAAP01001166.1_1 - 8.6e-07 29.3 0.2 0.0091 16.4 0.0 2.8 2 1 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 AAAP01001166.1_1 - 1.3e-06 27.9 5.7 1.8e-06 27.5 5.7 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel EGF_Tenascin PF18720.1 AAAP01001166.1_1 - 0.22 11.6 0.1 0.42 10.7 0.1 1.4 1 0 0 1 1 1 0 Tenascin EGF domain Autotransporter PF03797.19 AAAP01001168.1_1 - 8.4e-24 84.6 5.1 8.4e-24 84.6 5.1 2.2 2 0 0 2 2 2 2 Autotransporter beta-domain LON_substr_bdg PF02190.16 AAAP01001169.1_1 - 6.7e-13 49.0 0.0 5.8e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Trm112p PF03966.16 AAAP01001169.1_2 - 6e-09 36.3 0.1 1.3e-08 35.3 0.1 1.5 1 1 0 1 1 1 1 Trm112p-like protein PUA PF01472.20 AAAP01001170.1_1 - 1.3e-19 69.9 0.6 1.6e-19 69.6 0.6 1.1 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 AAAP01001170.1_1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 PUA-like domain DnaB_bind PF10410.9 AAAP01001170.1_2 - 0.0048 17.0 0.2 0.0048 17.0 0.2 2.9 2 1 1 3 3 3 1 DnaB-helicase binding domain of primase Cation_efflux PF01545.21 AAAP01001171.1_1 - 2.7e-12 46.8 0.1 3e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family HemolysinCabind PF00353.19 AAAP01001172.1_1 - 7.8e-07 29.0 19.1 1.2e-05 25.2 11.9 2.1 2 0 0 2 2 2 2 RTX calcium-binding nonapeptide repeat (4 copies) HemolysinCabind PF00353.19 AAAP01001172.1_2 - 2.1e-05 24.4 8.0 3.2e-05 23.8 7.2 1.8 1 1 0 1 1 1 1 RTX calcium-binding nonapeptide repeat (4 copies) Alpha-amylase PF00128.24 AAAP01001175.1_1 - 3.7e-27 95.8 0.0 1.1e-26 94.2 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Cytochrom_B_N_2 PF13631.6 AAAP01001176.1_1 - 6e-09 36.1 9.3 6.5e-09 36.0 9.3 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 AAAP01001176.1_1 - 1.2e-06 28.4 10.0 1.4e-06 28.3 10.0 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Aldose_epim PF01263.20 AAAP01001177.1_1 - 4.3e-41 141.2 0.0 4.7e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RsfS PF02410.15 AAAP01001177.1_2 - 1.5e-23 83.1 0.0 1.7e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CoA_binding_3 PF13727.6 AAAP01001178.1_2 - 0.014 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain DUF4330 PF14221.6 AAAP01001178.1_2 - 0.078 13.2 0.3 0.18 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Gram_pos_anchor PF00746.21 AAAP01001178.1_2 - 0.68 9.9 3.0 1.7 8.6 3.0 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Mur_ligase_C PF02875.21 AAAP01001179.1_2 - 0.0068 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain HhH-GPD PF00730.25 AAAP01001180.1_1 - 0.0073 16.8 0.0 0.008 16.6 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_pol3_chi PF04364.13 AAAP01001182.1_1 - 1.8e-08 34.6 0.1 1.9e-08 34.6 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC CoA_binding_2 PF13380.6 AAAP01001183.1_1 - 1.2e-07 32.3 0.0 1.3e-07 32.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Pribosyltran PF00156.27 AAAP01001184.1_1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AAAP01001184.1_1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Ribosomal_L1 PF00687.21 AAAP01001185.1_1 - 7.7e-34 117.2 0.0 9.7e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1e PF01406.19 AAAP01001187.1_1 - 1e-24 87.4 0.0 1.2e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain CoA_trans PF01144.23 AAAP01001188.1_1 - 8.5e-06 25.3 3.0 0.0004 19.9 0.0 3.2 3 1 0 3 3 3 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 AAAP01001188.1_1 - 0.18 10.1 5.0 0.071 11.4 0.7 2.0 1 1 1 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter MttA_Hcf106 PF02416.16 AAAP01001189.1_2 - 7.4e-16 57.2 0.0 7.9e-16 57.1 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family Mucin PF01456.17 AAAP01001189.1_2 - 0.0011 19.0 8.0 0.0013 18.7 8.0 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein LPG_synthase_TM PF03706.13 AAAP01001190.1_1 - 0.0025 17.4 14.1 0.0033 17.0 14.1 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region PQQ_2 PF13360.6 AAAP01001191.1_1 - 0.012 15.2 0.4 0.023 14.3 0.4 1.6 1 1 0 1 1 1 0 PQQ-like domain Peptidase_S9_N PF02897.15 AAAP01001191.1_2 - 1.3e-28 100.0 0.0 1.6e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Vir_act_alpha_C PF10400.9 AAAP01001191.1_2 - 0.059 14.1 0.2 0.082 13.6 0.2 1.2 1 0 0 1 1 1 0 Virulence activator alpha C-term TRCF PF03461.15 AAAP01001192.1_1 - 7.9e-16 58.2 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 TRCF domain Thiolase_N PF00108.23 AAAP01001193.1_2 - 2e-14 53.6 0.3 2.6e-14 53.2 0.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AAAP01001193.1_2 - 3.2e-14 52.5 0.2 9.4e-14 51.0 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 AAAP01001193.1_2 - 0.0043 16.4 0.0 0.0052 16.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_N PF00195.19 AAAP01001193.1_2 - 0.0092 15.4 0.8 0.024 14.0 0.4 1.7 1 1 1 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain FMN_red PF03358.15 AAAP01001193.1_2 - 0.029 14.1 1.5 0.1 12.3 1.3 2.0 1 1 0 1 1 1 0 NADPH-dependent FMN reductase NAD_binding_11 PF14833.6 AAAP01001193.1_2 - 0.23 11.7 3.5 1.8 8.8 0.3 2.8 2 1 1 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AAA_5 PF07728.14 AAAP01001194.1_1 - 2.1e-13 50.5 0.0 3.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01001194.1_1 - 6e-10 39.7 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01001194.1_1 - 8.4e-06 26.3 0.2 3.1e-05 24.4 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01001194.1_1 - 9.3e-05 22.7 0.1 0.0035 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01001194.1_1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAAP01001194.1_1 - 0.00029 20.8 0.2 0.0034 17.3 0.0 2.1 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 AAAP01001194.1_1 - 0.00068 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAAP01001194.1_1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 AAAP01001194.1_1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAAP01001194.1_1 - 0.0029 18.1 0.0 0.0049 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AAAP01001194.1_1 - 0.003 17.5 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_2 PF07724.14 AAAP01001194.1_1 - 0.0045 17.1 0.0 0.0098 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 AAAP01001194.1_1 - 0.0065 15.7 0.0 0.0093 15.2 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 AAAP01001194.1_1 - 0.0081 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AAAP01001194.1_1 - 0.01 16.2 0.1 0.038 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AAAP01001194.1_1 - 0.012 16.1 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAAP01001194.1_1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 AAAP01001194.1_1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 AAAP01001194.1_1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01001194.1_1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 AAAP01001194.1_1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 AAAP01001194.1_1 - 0.1 12.0 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 AAAP01001194.1_1 - 0.1 12.5 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AAAP01001194.1_1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AAAP01001194.1_1 - 0.17 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 AAAP01001194.1_1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 AAAP01001194.1_1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Resolvase PF00239.21 AAAP01001195.1_1 - 0.0004 20.5 0.0 0.00041 20.5 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain Resolvase PF00239.21 AAAP01001195.1_2 - 9.4e-07 29.0 0.1 2e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 AAAP01001195.1_2 - 0.0012 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Recombinase Band_3_cyto PF07565.13 AAAP01001195.1_3 - 0.0087 15.9 0.0 0.009 15.8 0.0 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DUF3606 PF12244.8 AAAP01001195.1_3 - 0.083 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Photo_RC PF00124.19 AAAP01001196.1_1 - 1.2e-67 227.9 16.7 2e-67 227.2 16.7 1.3 1 0 0 1 1 1 1 Photosynthetic reaction centre protein adh_short_C2 PF13561.6 AAAP01001198.1_2 - 3.8e-30 105.2 1.2 4.3e-30 105.0 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001198.1_2 - 1.1e-27 96.8 0.8 1.2e-27 96.6 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01001198.1_2 - 1.1e-09 38.5 0.2 1.4e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AAAP01001198.1_2 - 0.0089 15.9 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PUA PF01472.20 AAAP01001198.1_2 - 0.062 13.3 0.7 2.3 8.2 0.0 2.5 3 0 0 3 3 3 0 PUA domain ABC_tran PF00005.27 AAAP01001199.1_1 - 1.1e-28 100.5 0.0 1.4e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01001199.1_1 - 2e-08 34.4 0.0 5.7e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAAP01001199.1_1 - 1.7e-05 25.2 0.1 0.042 14.4 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 AAAP01001199.1_1 - 4e-05 24.1 0.3 8.3e-05 23.0 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAAP01001199.1_1 - 5.9e-05 22.6 0.1 0.00083 18.9 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAAP01001199.1_1 - 0.0016 18.7 0.4 0.037 14.3 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01001199.1_1 - 0.01 15.5 1.6 0.19 11.3 1.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAAP01001199.1_1 - 0.012 14.3 0.0 0.13 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAAP01001199.1_1 - 0.033 13.9 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GvpD PF07088.11 AAAP01001199.1_1 - 0.035 12.7 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_5 PF07728.14 AAAP01001199.1_1 - 0.041 13.9 0.1 0.86 9.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 AAAP01001199.1_1 - 0.078 12.9 0.2 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 AAAP01001199.1_1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 AAAP01001199.1_1 - 0.091 12.5 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 AAAP01001199.1_1 - 0.12 12.7 0.0 0.47 10.7 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ThiC_Rad_SAM PF01964.18 AAAP01001200.1_1 - 9.9e-70 235.4 0.1 1.2e-69 235.2 0.1 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family SLAC1 PF03595.17 AAAP01001201.1_1 - 2.1e-18 66.7 18.6 2.5e-18 66.4 18.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5579 PF17742.1 AAAP01001201.1_1 - 0.066 12.8 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5579) NHL PF01436.21 AAAP01001203.1_1 - 1.6e-11 43.6 1.7 5.2e-05 23.1 0.0 5.3 5 0 0 5 5 5 2 NHL repeat Lactonase PF10282.9 AAAP01001203.1_1 - 3.3e-10 39.8 0.0 4e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AAAP01001203.1_1 - 7.6e-09 34.6 0.0 7.9e-08 31.2 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain SGL PF08450.12 AAAP01001203.1_1 - 3.5e-05 23.5 0.0 0.012 15.3 0.0 3.1 1 1 3 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Frtz PF11768.8 AAAP01001203.1_1 - 0.0026 16.2 0.0 0.0031 15.9 0.0 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Cys_Met_Meta_PP PF01053.20 AAAP01001204.1_1 - 6.2e-78 262.0 0.0 6.9e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAAP01001204.1_1 - 1.6e-05 24.3 0.0 1.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAAP01001204.1_1 - 0.0033 16.5 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 AAAP01001204.1_1 - 0.05 12.1 0.0 0.26 9.7 0.0 1.9 1 1 0 1 1 1 0 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 AAAP01001204.1_1 - 0.063 12.6 0.0 0.074 12.3 0.0 1.3 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AP_endonuc_2 PF01261.24 AAAP01001205.1_1 - 4.4e-24 85.1 0.1 5e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SecB PF02556.14 AAAP01001206.1_1 - 0.088 12.7 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit SecB rve PF00665.26 AAAP01001207.1_1 - 5e-26 91.2 0.0 6.8e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01001207.1_1 - 6.2e-22 77.2 0.2 1.2e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01001207.1_1 - 0.00048 20.2 0.0 0.0021 18.2 0.0 2.0 1 1 1 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AAAP01001207.1_1 - 0.043 14.0 0.7 0.094 12.9 0.7 1.5 1 0 0 1 1 1 0 HTH-like domain CBM_6 PF03422.15 AAAP01001208.1_1 - 2.9e-20 72.8 6.0 6.2e-20 71.7 1.1 2.4 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) PKD PF00801.20 AAAP01001208.1_1 - 1.9e-07 30.8 11.8 4.6e-07 29.6 0.9 3.8 4 0 0 4 4 4 2 PKD domain DUF5010_C PF18099.1 AAAP01001208.1_1 - 7.6e-06 26.0 1.6 1.6e-05 25.0 0.4 2.0 2 0 0 2 2 2 1 DUF5010 C-terminal domain Big_7 PF17957.1 AAAP01001208.1_1 - 0.08 13.7 9.8 0.78 10.5 0.0 4.0 4 1 0 4 4 4 0 Bacterial Ig domain TetR_C_7 PF14246.6 AAAP01001209.1_1 - 1.3e-07 31.7 0.1 2.1e-07 31.0 0.1 1.4 1 1 1 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain Hydrolase_like PF13242.6 AAAP01001210.1_2 - 7.3e-08 32.4 0.0 8.1e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AAAP01001210.1_2 - 3.9e-06 27.1 0.0 4.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01001210.1_2 - 0.0016 18.8 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ala_racemase_N PF01168.20 AAAP01001211.1_1 - 3.5e-07 30.1 5.2 4.8e-07 29.7 5.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain YccF PF03733.13 AAAP01001211.1_2 - 3.8e-33 113.9 30.7 3.4e-20 72.5 15.4 2.1 2 0 0 2 2 2 2 Inner membrane component domain DUF2189 PF09955.9 AAAP01001211.1_2 - 0.39 11.0 8.9 2.2 8.5 1.5 2.3 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF2628 PF10947.8 AAAP01001211.1_2 - 1.8 9.0 18.2 3.6 8.0 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) Acetyltransf_4 PF13420.7 AAAP01001212.1_1 - 1e-10 42.0 0.0 1.2e-10 41.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01001212.1_1 - 3.2e-09 37.0 0.0 4.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAAP01001212.1_1 - 1.8e-05 25.4 0.0 2.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01001212.1_1 - 2.3e-05 24.3 0.0 3.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01001212.1_1 - 3.4e-05 23.7 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 AAAP01001212.1_1 - 5.6e-05 23.5 0.0 7.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAAP01001212.1_1 - 0.0039 16.9 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AAAP01001212.1_1 - 0.034 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_13 PF13880.6 AAAP01001212.1_1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase GntR PF00392.21 AAAP01001212.1_2 - 0.015 14.9 0.1 0.027 14.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 AAAP01001212.1_2 - 0.027 14.4 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 MarR family Dimerisation PF08100.11 AAAP01001212.1_2 - 0.054 13.5 0.5 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 Dimerisation domain HTH_29 PF13551.6 AAAP01001212.1_2 - 0.061 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HemN_C PF06969.16 AAAP01001212.1_2 - 0.09 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 HemN C-terminal domain NAD_kinase PF01513.21 AAAP01001213.1_1 - 0.0018 17.5 0.3 0.022 14.0 0.1 2.0 2 0 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 AAAP01001213.1_1 - 0.18 11.4 0.4 0.42 10.2 0.1 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain LZ_Tnp_IS66 PF13007.7 AAAP01001214.1_1 - 8e-16 58.6 6.3 1.2e-15 58.0 6.3 1.3 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain zf-IS66 PF13005.7 AAAP01001214.1_1 - 1.5e-12 47.7 1.5 2.9e-12 46.8 0.3 2.0 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 TnpB_IS66 PF05717.13 AAAP01001214.1_2 - 1.7e-17 63.1 0.0 2e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein Aminotran_1_2 PF00155.21 AAAP01001215.1_1 - 2.1e-17 63.3 0.0 2.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DEAD PF00270.29 AAAP01001216.1_1 - 9e-09 35.3 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01001216.1_1 - 0.01 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Metallophos_2 PF12850.7 AAAP01001218.1_1 - 0.00023 21.4 0.0 0.00024 21.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAAP01001218.1_1 - 0.0091 16.5 0.0 0.0097 16.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hydrolase_3 PF08282.12 AAAP01001219.1_1 - 9.8e-23 81.2 0.0 2e-22 80.2 0.0 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAAP01001219.1_1 - 3.9e-06 26.6 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AAAP01001219.1_1 - 0.00015 22.1 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01001219.1_1 - 0.03 14.7 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rib PF08428.10 AAAP01001219.1_1 - 0.069 13.2 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Rib/alpha-like repeat TetR_C_7 PF14246.6 AAAP01001220.1_1 - 1.1e-16 60.9 0.1 1.9e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AAAP01001220.1_1 - 4.9e-06 26.2 0.0 1.8e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DprA_WH PF17782.1 AAAP01001220.1_1 - 0.011 15.8 0.3 0.026 14.6 0.3 1.5 1 0 0 1 1 1 0 DprA winged helix domain Phage_NinH PF06322.11 AAAP01001220.1_1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage NinH protein HTH_31 PF13560.6 AAAP01001220.1_1 - 0.21 12.0 2.9 0.21 12.0 0.5 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAAP01001220.1_1 - 0.21 11.7 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase IlvN PF07991.12 AAAP01001220.1_2 - 1.5e-15 57.1 0.4 1.7e-15 57.0 0.4 1.0 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 AAAP01001220.1_2 - 0.00055 20.0 0.1 0.00061 19.9 0.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 AAAP01001220.1_2 - 0.00069 19.7 0.1 0.00074 19.6 0.1 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AAAP01001220.1_2 - 0.002 17.5 0.0 0.0023 17.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family F420_oxidored PF03807.17 AAAP01001220.1_2 - 0.0053 17.3 0.1 0.0058 17.2 0.1 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAAP01001220.1_2 - 0.011 15.1 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAAP01001220.1_2 - 0.027 14.9 0.2 0.033 14.6 0.2 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.19 AAAP01001220.1_2 - 0.055 12.2 0.0 0.055 12.2 0.0 1.0 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase FAD_binding_3 PF01494.19 AAAP01001220.1_2 - 0.069 12.4 0.1 0.074 12.3 0.1 1.0 1 0 0 1 1 1 0 FAD binding domain GARS_N PF02844.15 AAAP01001220.1_2 - 0.074 13.8 0.1 0.085 13.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain TPP_enzyme_M PF00205.22 AAAP01001221.1_1 - 3.3e-35 120.8 0.0 4.5e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 AAAP01001221.1_1 - 2.9e-22 79.1 0.1 5.3e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Bac_luciferase PF00296.20 AAAP01001223.1_1 - 1.7e-46 159.1 13.8 2.1e-46 158.8 13.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AA_permease_2 PF13520.6 AAAP01001223.1_2 - 1 8.1 9.3 1.1 8.0 9.3 1.0 1 0 0 1 1 1 0 Amino acid permease ABC_tran PF00005.27 AAAP01001224.1_1 - 7e-20 72.0 0.0 2.1e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_tran_Xtn PF12848.7 AAAP01001224.1_1 - 6.7e-16 58.1 6.5 1.1e-15 57.4 6.5 1.4 1 0 0 1 1 1 1 ABC transporter ATP-synt_E PF05680.12 AAAP01001224.1_1 - 0.057 13.8 2.7 0.099 13.0 2.7 1.4 1 0 0 1 1 1 0 ATP synthase E chain AAA_29 PF13555.6 AAAP01001224.1_1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01001224.1_1 - 0.61 9.8 1.8 24 4.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_21 PF13304.6 AAAP01001227.1_2 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAAP01001227.1_2 - 0.014 15.9 0.0 0.028 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SMC_N PF02463.19 AAAP01001227.1_2 - 0.18 11.2 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Glyco_trans_4_4 PF13579.6 AAAP01001228.1_1 - 4.7e-17 62.9 3.1 4.7e-17 62.9 3.1 1.8 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01001228.1_1 - 7.2e-15 55.4 0.2 1.1e-14 54.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01001228.1_1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01001228.1_1 - 1.3e-09 38.5 0.0 8e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AAAP01001228.1_1 - 0.0016 18.5 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like Sel1 PF08238.12 AAAP01001229.1_1 - 2.7e-25 88.2 6.3 3.5e-11 43.4 0.1 4.8 5 0 0 5 5 5 4 Sel1 repeat HemY_N PF07219.13 AAAP01001229.1_1 - 0.0049 17.1 1.8 0.0076 16.4 0.2 2.0 2 0 0 2 2 2 1 HemY protein N-terminus TPR_6 PF13174.6 AAAP01001229.1_1 - 0.14 12.9 4.7 32 5.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.6 AAAP01001230.1_2 - 5.9e-15 55.8 0.0 7.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01001230.1_2 - 3.2e-06 27.6 0.0 3.3e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01001230.1_2 - 9.8e-06 25.6 0.2 0.0025 17.9 0.0 2.3 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01001230.1_2 - 1.8e-05 25.2 0.0 2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01001230.1_2 - 0.021 14.6 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LysR_substrate PF03466.20 AAAP01001231.1_1 - 1.2e-21 77.0 2.9 1.4e-21 76.9 2.9 1.0 1 0 0 1 1 1 1 LysR substrate binding domain PP-binding PF00550.25 AAAP01001232.1_2 - 8.9e-05 22.8 0.3 0.00013 22.2 0.3 1.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site Nrap_D4 PF17405.2 AAAP01001232.1_2 - 0.13 11.7 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 adh_short PF00106.25 AAAP01001232.1_4 - 1.8e-10 40.6 0.0 2e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01001232.1_4 - 1.9e-09 37.7 0.0 2.2e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 AAAP01001232.1_4 - 0.016 14.8 0.0 0.018 14.6 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HTH_31 PF13560.6 AAAP01001233.1_1 - 1.2e-11 44.8 1.4 1.2e-11 44.8 1.4 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01001233.1_1 - 1.8e-11 43.9 0.5 4.6e-11 42.6 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix EPSP_synthase PF00275.20 AAAP01001233.1_1 - 5.5e-09 35.2 0.1 8.1e-09 34.7 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HTH_19 PF12844.7 AAAP01001233.1_1 - 1.5e-08 34.5 0.2 2.7e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01001233.1_1 - 3.4e-06 26.9 0.8 1.2e-05 25.1 0.3 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01001233.1_1 - 8.1e-05 22.1 0.4 0.00019 20.9 0.2 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 AAAP01001233.1_1 - 0.00012 22.4 0.1 0.00022 21.6 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_IclR PF09339.10 AAAP01001233.1_1 - 0.00014 21.5 1.7 0.00034 20.4 0.3 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AAAP01001233.1_1 - 0.00028 20.4 0.4 0.00062 19.2 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 AAAP01001233.1_1 - 0.0012 18.7 0.2 0.0029 17.5 0.2 1.6 1 0 0 1 1 1 1 MarR family HTH_25 PF13413.6 AAAP01001233.1_1 - 0.0016 18.3 0.3 0.0056 16.5 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAAP01001233.1_1 - 0.0037 17.1 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 AAAP01001233.1_1 - 0.014 15.1 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAAP01001233.1_1 - 0.016 15.0 0.6 0.087 12.7 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 AAAP01001233.1_1 - 0.024 14.4 0.7 0.31 10.8 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 AAAP01001233.1_1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 AAAP01001233.1_1 - 0.029 14.3 0.2 0.094 12.7 0.2 1.9 1 0 0 1 1 1 0 HTH domain HTH_Crp_2 PF13545.6 AAAP01001233.1_1 - 0.061 13.3 1.4 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_50 PF18024.1 AAAP01001233.1_1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SBP_bac_1 PF01547.25 AAAP01001234.1_2 - 6.8e-05 23.0 0.1 9e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAAP01001234.1_2 - 0.0094 15.8 0.3 0.012 15.4 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PASTA PF03793.19 AAAP01001235.1_2 - 5.6e-06 26.1 0.1 1.7e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 PASTA domain BRCT PF00533.26 AAAP01001235.1_3 - 0.0023 18.3 0.0 0.0024 18.2 0.0 1.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 AAAP01001235.1_3 - 0.016 15.1 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 twin BRCT domain YkuD PF03734.14 AAAP01001236.1_1 - 1.2e-18 67.9 0.0 2.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Polysacc_deac_2 PF04748.13 AAAP01001237.1_1 - 3.2e-32 111.4 0.0 3.6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase NUDIX PF00293.28 AAAP01001237.1_2 - 5.1e-06 26.6 0.1 6.4e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Toluene_X PF03349.16 AAAP01001238.1_2 - 3.4e-37 128.1 0.0 4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) Porin_4 PF13609.6 AAAP01001238.1_2 - 0.00052 19.9 0.1 0.0062 16.3 0.0 2.2 1 1 0 2 2 2 1 Gram-negative porin OMP_b-brl PF13505.6 AAAP01001238.1_2 - 0.0016 18.6 0.2 0.016 15.3 0.2 2.6 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain YadA_anchor PF03895.15 AAAP01001238.1_2 - 0.0065 16.5 1.6 26 5.0 0.1 4.5 3 2 2 5 5 5 0 YadA-like membrane anchor domain TonB_dep_Rec PF00593.24 AAAP01001238.1_2 - 0.0085 16.0 4.2 0.023 14.6 4.2 1.7 1 1 0 1 1 1 1 TonB dependent receptor DUF2490 PF10677.9 AAAP01001238.1_2 - 0.0099 15.8 0.1 3.6 7.5 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF2490) Autotransporter PF03797.19 AAAP01001238.1_2 - 0.038 13.6 0.1 0.092 12.4 0.1 1.6 1 1 0 1 1 1 0 Autotransporter beta-domain BBP2 PF07642.11 AAAP01001238.1_2 - 0.041 13.0 0.0 0.15 11.1 0.0 1.7 1 1 1 2 2 2 0 Putative beta-barrel porin-2, OmpL-like. bbp2 Porin_3 PF01459.22 AAAP01001238.1_2 - 0.056 12.9 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic porin MtrB_PioB PF11854.8 AAAP01001238.1_2 - 0.07 11.5 0.0 0.46 8.8 0.0 2.0 1 1 1 2 2 2 0 Putative outer membrane beta-barrel porin, MtrB/PioB DUF3187 PF11383.8 AAAP01001238.1_2 - 0.22 10.7 0.0 1.9 7.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3187) EFP PF01132.20 AAAP01001239.1_1 - 3.2e-24 84.7 0.0 8.3e-24 83.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Elong-fact-P_C PF09285.11 AAAP01001239.1_1 - 1.4e-20 72.8 0.8 3e-20 71.7 0.8 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 AAAP01001239.1_1 - 1.4e-15 57.0 0.3 2.9e-15 56.0 0.1 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain TetR_C_33 PF13305.6 AAAP01001240.1_2 - 0.026 15.3 0.9 0.39 11.5 0.1 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ADH_zinc_N PF00107.26 AAAP01001241.1_1 - 9.2e-05 22.4 0.0 9.4e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HTH_20 PF12840.7 AAAP01001241.1_2 - 1.9e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAAP01001241.1_2 - 0.00046 20.0 1.7 0.0038 17.0 0.1 2.5 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AAAP01001241.1_2 - 0.00089 19.0 0.5 0.0015 18.3 0.1 1.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain TrmB PF01978.19 AAAP01001241.1_2 - 0.046 13.6 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAAP01001241.1_2 - 0.058 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator LON_substr_bdg PF02190.16 AAAP01001241.1_2 - 0.063 13.1 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain HTH_24 PF13412.6 AAAP01001241.1_2 - 0.075 12.6 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAAP01001241.1_2 - 0.087 12.8 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain LacI PF00356.21 AAAP01001241.1_2 - 0.15 11.9 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Iso_dh PF00180.20 AAAP01001242.1_1 - 0.00023 20.4 0.0 0.00027 20.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fae PF08714.11 AAAP01001242.1_3 - 3.4e-21 75.8 0.2 4.1e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) AAA_lid_2 PF17863.1 AAAP01001243.1_1 - 3.1e-11 42.9 1.8 3.1e-11 42.9 1.8 2.8 3 0 0 3 3 3 2 AAA lid domain Peptidase_S11 PF00768.20 AAAP01001245.1_1 - 5.3e-32 111.2 0.0 6.9e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAAP01001245.1_1 - 0.092 12.3 0.1 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Beta-lactamase enzyme family dCache_1 PF02743.18 AAAP01001246.1_1 - 1.9e-13 50.8 0.0 2.3e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Cache domain MFS_1 PF07690.16 AAAP01001248.1_1 - 1e-06 28.0 18.0 1e-06 28.0 18.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CitMHS PF03600.16 AAAP01001248.1_1 - 0.38 9.9 15.2 0.62 9.2 15.2 1.3 1 0 0 1 1 1 0 Citrate transporter RDD PF06271.12 AAAP01001248.1_2 - 8.4e-17 61.7 4.4 1.3e-16 61.1 4.4 1.3 1 0 0 1 1 1 1 RDD family Transposase_20 PF02371.16 AAAP01001249.1_1 - 1.4e-18 67.0 0.2 2.7e-18 66.1 0.2 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family SbcCD_C PF13558.6 AAAP01001250.1_1 - 8.2e-13 48.4 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit F_bP_aldolase PF01116.20 AAAP01001251.1_1 - 1.1e-47 162.8 0.0 1.6e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF4797 PF16051.5 AAAP01001251.1_1 - 0.12 12.3 0.4 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) Peripla_BP_3 PF13377.6 AAAP01001251.1_2 - 1.1e-06 29.1 1.2 0.006 16.9 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein-like domain HpcH_HpaI PF03328.14 AAAP01001253.1_2 - 9.6e-35 119.7 0.1 1.2e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RNA_pol_Rpb2_2 PF04561.14 AAAP01001255.1_1 - 1e-13 51.4 0.0 4.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 DUF1491 PF07372.12 AAAP01001257.1_1 - 1e-31 109.4 0.2 1.2e-31 109.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1491) PG_binding_1 PF01471.18 AAAP01001257.1_2 - 4.7e-10 39.5 0.0 5.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 AAAP01001257.1_2 - 0.0046 17.2 0.1 0.0091 16.2 0.1 1.6 1 1 0 1 1 1 1 Predicted Peptidoglycan domain HemolysinCabind PF00353.19 AAAP01001258.1_1 - 5.7e-22 77.3 63.6 9.1e-07 28.8 10.7 5.8 4 3 1 5 5 5 5 RTX calcium-binding nonapeptide repeat (4 copies) Leader_Thr PF08254.11 AAAP01001258.1_1 - 3.6 7.4 8.6 5.6 6.8 1.0 2.9 2 0 0 2 2 2 0 Threonine leader peptide Big_1 PF02369.16 AAAP01001259.1_1 - 0.12 12.4 0.3 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF4124 PF13511.6 AAAP01001259.1_1 - 0.18 12.1 1.1 0.4 11.0 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4124) TMP_2 PF06791.13 AAAP01001259.1_4 - 0.055 13.1 9.4 0.068 12.8 9.4 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF5536 PF17688.1 AAAP01001259.1_4 - 0.33 10.8 4.5 0.37 10.7 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Laminin_G_3 PF13385.6 AAAP01001260.1_1 - 8.6e-07 29.2 0.3 2.2e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Sigma70_ner PF04546.13 AAAP01001261.1_1 - 3.7e-26 92.3 0.2 3.7e-26 92.3 0.2 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region Sigma70_r1_2 PF00140.20 AAAP01001261.1_1 - 2.3e-14 53.1 0.4 2.3e-14 53.1 0.4 1.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 YmdB PF13277.6 AAAP01001262.1_1 - 2.8e-79 266.1 0.0 3.1e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.10 AAAP01001262.1_1 - 0.1 12.0 1.2 7.4 5.9 0.0 2.3 2 1 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Methyltransf_33 PF10017.9 AAAP01001263.1_1 - 1.8e-68 231.0 0.0 2e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent ApbA_C PF08546.11 AAAP01001264.1_1 - 1.2e-29 103.1 0.0 1.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Nudix_N PF12535.8 AAAP01001264.1_1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal AMP-binding PF00501.28 AAAP01001264.1_2 - 7.5e-56 189.5 0.0 1e-55 189.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 AAAP01001264.1_2 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Acetyltransf_1 PF00583.25 AAAP01001265.1_2 - 4.7e-08 33.3 0.0 8.5e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01001265.1_2 - 2.3e-05 24.7 0.0 5.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01001265.1_2 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01001265.1_2 - 0.0048 16.8 0.2 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 AAAP01001265.1_2 - 0.18 11.9 0.2 0.44 10.7 0.2 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Abhydrolase_1 PF00561.20 AAAP01001266.1_2 - 4.8e-11 42.8 0.0 1.7e-09 37.7 0.0 2.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01001266.1_2 - 3.5e-10 40.9 0.1 4.1e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01001266.1_2 - 1.1e-08 34.6 0.0 4.3e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 AAAP01001266.1_2 - 0.029 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AI-2E_transport PF01594.16 AAAP01001267.1_1 - 8.7e-36 123.7 21.3 1e-35 123.5 21.3 1.0 1 0 0 1 1 1 1 AI-2E family transporter CPP1-like PF11833.8 AAAP01001267.1_1 - 0.0098 15.6 0.9 0.0098 15.6 0.9 2.5 3 0 0 3 3 3 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Vpu PF00558.19 AAAP01001267.1_1 - 0.84 9.4 0.0 0.84 9.4 0.0 2.6 2 1 0 2 2 2 0 Vpu protein Mntp PF02659.15 AAAP01001267.1_1 - 1.6 8.5 15.0 0.21 11.4 5.3 2.6 2 2 0 2 2 2 0 Putative manganese efflux pump Glyco_transf_21 PF13506.6 AAAP01001268.1_1 - 0.0026 17.3 0.7 0.0051 16.3 0.7 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 GGDEF PF00990.21 AAAP01001269.1_1 - 2.3e-34 118.5 0.0 2.6e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAAP01001269.1_1 - 0.00051 20.3 0.5 0.00068 19.9 0.5 1.2 1 0 0 1 1 1 1 GGDEF-like domain GA-like PF17573.2 AAAP01001269.1_2 - 0.21 11.5 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 GA-like domain CN_hydrolase PF00795.22 AAAP01001270.1_1 - 5.5e-22 78.3 0.0 7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Radical_SAM PF04055.21 AAAP01001270.1_2 - 4.4e-12 46.7 0.0 6.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily CMD PF02627.20 AAAP01001270.1_2 - 0.09 12.8 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family HEAT_2 PF13646.6 AAAP01001271.1_1 - 0.00091 19.6 5.2 0.0033 17.8 5.2 2.0 1 0 0 1 1 1 1 HEAT repeats FCD PF07729.12 AAAP01001271.1_1 - 0.044 14.2 0.7 0.044 14.2 0.7 2.6 3 2 0 3 3 3 0 FCD domain Peptidase_S9_N PF02897.15 AAAP01001272.1_1 - 1.3e-20 73.6 0.0 1.7e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1176 PF06674.11 AAAP01001272.1_1 - 0.19 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) KR PF08659.10 AAAP01001273.1_1 - 1.5e-54 184.7 1.4 6.3e-52 176.1 0.0 2.1 2 0 0 2 2 2 2 KR domain ADH_zinc_N PF00107.26 AAAP01001273.1_1 - 2.7e-24 85.6 0.4 6.1e-24 84.5 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01001273.1_1 - 6.9e-23 82.2 0.0 1.5e-22 81.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 AAAP01001273.1_1 - 4e-16 59.1 0.7 2.6e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01001273.1_1 - 4.4e-08 33.0 1.4 6.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 AAAP01001273.1_1 - 0.0024 17.8 0.6 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 AAAP01001273.1_1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAAP01001273.1_1 - 0.024 14.1 0.6 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 AAAP01001273.1_1 - 0.083 12.5 0.9 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 SLOG cluster4 family RmlD_sub_bind PF04321.17 AAAP01001273.1_1 - 0.27 10.3 0.5 6.9 5.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Flavodoxin_1 PF00258.25 AAAP01001274.1_1 - 4.9e-15 56.0 0.0 6.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin AsnC_trans_reg PF01037.21 AAAP01001274.1_2 - 2.8e-23 81.7 0.1 4.2e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AAAP01001274.1_2 - 4.4e-18 64.8 0.2 7.3e-18 64.1 0.2 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAAP01001274.1_2 - 1.5e-17 62.8 0.2 2.2e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAAP01001274.1_2 - 0.00015 21.6 0.1 0.00025 20.9 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 AAAP01001274.1_2 - 0.0073 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.27 AAAP01001274.1_2 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Crp_2 PF13545.6 AAAP01001274.1_2 - 0.045 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4286 PF14114.6 AAAP01001274.1_2 - 0.086 13.3 0.0 1.2 9.7 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4286) MarR PF01047.22 AAAP01001274.1_2 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 AAAP01001274.1_2 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 MarR family HxlR PF01638.17 AAAP01001274.1_2 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PAZ_siRNAbind PF12212.8 AAAP01001274.1_2 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 PAZ domain GerE PF00196.19 AAAP01001275.1_1 - 2.4e-19 68.6 0.9 3.4e-19 68.1 0.9 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01001275.1_1 - 0.0016 18.1 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01001275.1_1 - 0.083 12.4 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 AAAP01001275.1_1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Glycos_transf_2 PF00535.26 AAAP01001275.1_2 - 0.00075 19.3 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 IucA_IucC PF04183.12 AAAP01001276.1_1 - 3.2e-70 236.4 0.6 3.7e-70 236.2 0.6 1.0 1 0 0 1 1 1 1 IucA / IucC family NifU PF01106.17 AAAP01001277.1_1 - 1.3e-25 89.3 0.0 1.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 AAAP01001277.1_1 - 1.3e-23 82.9 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal SepF PF04472.12 AAAP01001277.1_1 - 0.18 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Cell division protein SepF ABC_tran PF00005.27 AAAP01001278.1_2 - 2.7e-15 57.1 0.0 3.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01001278.1_2 - 0.0015 18.0 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAAP01001278.1_2 - 0.18 12.1 0.2 3.7 7.8 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ILVD_EDD PF00920.21 AAAP01001280.1_2 - 0.0024 16.6 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family UPF0262 PF06793.12 AAAP01001281.1_1 - 4.7e-10 39.8 0.0 5.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) Histidinol_dh PF00815.20 AAAP01001281.1_2 - 1.9e-167 557.5 0.6 2.2e-167 557.2 0.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF1134 PF06577.12 AAAP01001282.1_1 - 4.1e-09 36.4 0.0 6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1134) Inositol_P PF00459.25 AAAP01001282.1_2 - 3.3e-37 128.5 0.0 4.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family MCM_lid PF17855.1 AAAP01001283.1_1 - 0.11 12.9 0.3 0.48 10.9 0.1 2.1 2 0 0 2 2 2 0 MCM AAA-lid domain Acetyltransf_3 PF13302.7 AAAP01001284.1_1 - 2.2e-13 51.1 0.1 2.4e-13 51.0 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01001284.1_1 - 1.9e-09 37.8 0.1 2.3e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01001284.1_1 - 3.8e-06 27.2 0.2 8e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01001284.1_1 - 4.2e-06 26.7 0.1 4.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAAP01001284.1_1 - 0.0058 16.3 0.1 0.0088 15.7 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAAP01001284.1_1 - 0.019 15.1 0.1 0.12 12.4 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AAAP01001284.1_1 - 0.11 12.1 0.1 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase B3_4 PF03483.17 AAAP01001285.1_1 - 2.4e-36 125.0 0.0 3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain Peripla_BP_6 PF13458.6 AAAP01001286.1_1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.0 1 0 0 1 1 1 0 Periplasmic binding protein sCache_3_2 PF17203.4 AAAP01001286.1_2 - 0.077 13.1 0.5 0.099 12.8 0.5 1.4 1 1 0 1 1 1 0 Single cache domain 3 YbgS PF13985.6 AAAP01001286.1_2 - 0.14 12.5 0.9 0.16 12.3 0.1 1.6 2 0 0 2 2 2 0 YbgS-like protein Glycos_transf_1 PF00534.20 AAAP01001286.1_3 - 1.2e-18 67.3 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01001286.1_3 - 8.6e-16 58.6 0.2 1.1e-15 58.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01001286.1_3 - 4.9e-08 33.3 0.0 5.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 YceI PF04264.13 AAAP01001287.1_1 - 1.4e-42 145.7 1.1 1.6e-42 145.5 1.1 1.0 1 0 0 1 1 1 1 YceI-like domain Ribonuc_red_lgC PF02867.15 AAAP01001288.1_1 - 3e-55 187.7 0.0 5.6e-55 186.9 0.0 1.4 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Transcrip_reg PF01709.20 AAAP01001288.1_1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator DUF1849 PF08904.11 AAAP01001288.1_1 - 0.048 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Ribonuc_red_lgC PF02867.15 AAAP01001288.1_2 - 0.02 13.4 0.1 0.02 13.4 0.1 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Lon_C PF05362.13 AAAP01001289.1_1 - 5.1e-83 277.6 1.3 6.2e-83 277.4 1.3 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 AAAP01001289.1_1 - 2.5e-10 40.3 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase GIDA PF01134.22 AAAP01001290.1_1 - 3.1e-103 345.9 0.0 3.5e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AAAP01001290.1_1 - 0.0078 16.2 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 AAAP01001290.1_1 - 0.056 12.5 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF3659 PF12396.8 AAAP01001290.1_1 - 0.16 11.9 0.1 0.71 9.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) DUF4020 PF13212.6 AAAP01001291.1_1 - 0.09 12.6 0.0 0.094 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) YbgS PF13985.6 AAAP01001291.1_2 - 0.33 11.2 3.9 0.52 10.6 3.0 1.8 1 1 1 2 2 2 0 YbgS-like protein LisH_2 PF16045.5 AAAP01001292.1_1 - 0.19 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 LisH Ppx-GppA PF02541.16 AAAP01001293.1_1 - 4.5e-39 134.6 0.0 5.5e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DALR_1 PF05746.15 AAAP01001295.1_1 - 0.0024 18.1 0.1 0.0025 18.0 0.1 1.1 1 0 0 1 1 1 1 DALR anticodon binding domain HAD_2 PF13419.6 AAAP01001297.1_1 - 2.2e-26 93.0 0.0 2.6e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01001297.1_1 - 3.1e-18 66.8 0.2 4.8e-17 63.0 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01001297.1_1 - 3.5e-05 23.8 0.3 6.2e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAAP01001297.1_1 - 4.2e-05 23.6 0.0 0.063 13.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01001297.1_1 - 0.056 13.8 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD-oxidase_C PF02913.19 AAAP01001299.1_1 - 2.4e-54 184.6 0.0 2.7e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ZT_dimer PF16916.5 AAAP01001300.1_1 - 6.4e-06 26.2 0.6 8.4e-06 25.8 0.6 1.1 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DNA_binding_1 PF01035.20 AAAP01001300.1_2 - 3.7e-32 110.3 0.8 3.7e-32 110.3 0.8 2.1 2 1 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 AAAP01001300.1_2 - 1.4e-28 98.7 4.9 3.4e-28 97.5 4.9 1.7 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 AAAP01001300.1_2 - 5.6e-19 68.2 2.1 1.4e-18 67.0 0.1 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01001300.1_2 - 1.3e-09 37.9 0.0 4.9e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family Methyltransf_1N PF02870.15 AAAP01001300.1_2 - 0.0014 19.4 0.0 0.0023 18.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Phage_integrase PF00589.22 AAAP01001301.1_1 - 5.7e-11 42.5 0.0 9.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family TadE PF07811.12 AAAP01001302.1_2 - 5.4e-06 26.6 7.6 5.4e-06 26.6 7.6 1.5 2 0 0 2 2 2 1 TadE-like protein Tad PF13400.6 AAAP01001302.1_2 - 2.3e-05 24.6 8.8 2.3e-05 24.6 8.8 1.7 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like Flp_Fap PF04964.14 AAAP01001302.1_2 - 0.0013 18.5 0.4 0.0027 17.5 0.4 1.6 1 1 0 1 1 1 1 Flp/Fap pilin component TadF PF16964.5 AAAP01001302.1_2 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF4244 PF14029.6 AAAP01001302.1_2 - 0.16 11.4 6.7 0.24 10.9 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4244) RNase_E_G PF10150.9 AAAP01001303.1_1 - 3e-23 82.6 0.0 4.6e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease E/G family PCB_OB PF17092.5 AAAP01001303.1_1 - 0.00025 21.7 0.1 0.049 14.4 0.1 2.3 1 1 1 2 2 2 2 Penicillin-binding protein OB-like domain S1 PF00575.23 AAAP01001303.1_1 - 0.0085 16.4 0.0 0.024 15.0 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain SMC_N PF02463.19 AAAP01001306.1_1 - 0.051 13.0 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Herpes_DNAp_acc PF04929.12 AAAP01001306.1_2 - 0.29 10.1 2.6 0.36 9.7 2.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ELFV_dehydrog PF00208.21 AAAP01001307.1_1 - 2.7e-83 279.4 1.7 3.3e-83 279.2 1.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AAAP01001307.1_1 - 3.7e-48 162.7 0.0 6.1e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AAAP01001307.1_1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAAP01001307.1_1 - 0.12 12.9 0.3 0.2 12.1 0.3 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ACR_tran PF00873.19 AAAP01001308.1_1 - 1e-23 83.1 0.5 1.3e-23 82.8 0.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAAP01001308.1_1 - 0.0042 16.5 0.1 0.0052 16.2 0.1 1.0 1 0 0 1 1 1 1 Protein export membrane protein TMEM215 PF15746.5 AAAP01001308.1_1 - 0.24 10.8 0.2 0.35 10.3 0.2 1.2 1 0 0 1 1 1 0 TMEM215 family ACR_tran PF00873.19 AAAP01001308.1_2 - 2.2e-38 131.6 0.0 2.4e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3040 PF11239.8 AAAP01001308.1_2 - 0.035 14.4 0.5 0.13 12.6 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) HlyD_D23 PF16576.5 AAAP01001309.1_2 - 2.3e-15 56.4 4.2 2.4e-14 53.1 4.3 2.0 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01001309.1_2 - 6.7e-13 49.3 0.2 2e-09 38.1 0.1 2.4 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01001309.1_2 - 4.4e-12 45.6 0.1 1.9e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01001309.1_2 - 0.003 17.3 0.1 0.039 13.8 0.0 2.4 2 1 0 2 2 2 1 Biotin-requiring enzyme VWA_3_C PF18571.1 AAAP01001309.1_2 - 0.0056 16.5 0.1 0.025 14.4 0.1 2.1 1 0 0 1 1 1 1 von Willebrand factor type A C-terminal domain Fil_haemagg PF05594.14 AAAP01001309.1_2 - 0.034 14.7 0.9 0.034 14.7 0.9 2.2 2 0 0 2 2 2 0 Haemagluttinin repeat Peptidase_M1_N PF17900.1 AAAP01001309.1_2 - 0.092 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain Troponin-I_N PF11636.8 AAAP01001309.1_2 - 7 6.7 14.6 0.36 10.8 7.8 2.4 2 1 0 2 2 2 0 Troponin I residues 1-32 DegT_DnrJ_EryC1 PF01041.17 AAAP01001310.1_2 - 1.6e-47 162.6 0.1 1.9e-47 162.3 0.1 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AAAP01001310.1_2 - 0.0011 18.3 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01001310.1_2 - 0.019 13.5 0.0 0.022 13.3 0.0 1.0 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAAP01001310.1_2 - 0.048 12.6 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01001310.1_2 - 0.069 12.4 0.0 0.2 10.9 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Sigma70_r4_2 PF08281.12 AAAP01001312.1_1 - 2.7e-16 59.0 0.0 3.2e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01001312.1_1 - 3.3e-07 29.7 0.0 4.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01001312.1_1 - 0.00026 20.7 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Mga PF08280.11 AAAP01001312.1_1 - 0.00081 19.4 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_ECF PF07638.11 AAAP01001312.1_1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.0 1 0 0 1 1 1 1 ECF sigma factor HTH_28 PF13518.6 AAAP01001312.1_1 - 0.004 17.2 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAAP01001312.1_1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain GerE PF00196.19 AAAP01001312.1_1 - 0.019 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 AAAP01001312.1_1 - 0.037 13.9 0.1 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_AsnC-type PF13404.6 AAAP01001312.1_1 - 0.062 13.1 0.1 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain AA_permease_2 PF13520.6 AAAP01001313.1_1 - 4.5e-31 108.1 20.1 5.2e-31 107.9 20.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01001313.1_1 - 4.6e-28 98.0 18.3 5.8e-28 97.7 18.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 AAAP01001313.1_1 - 0.0002 20.2 0.1 0.00059 18.6 0.0 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein HCV_NS4a PF01006.20 AAAP01001313.1_1 - 0.052 13.3 0.5 0.052 13.3 0.5 4.0 5 1 1 6 6 6 0 Hepatitis C virus non-structural protein NS4a DUF4164 PF13747.6 AAAP01001314.1_1 - 8.1e-14 51.7 1.9 8.6e-14 51.6 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) CLZ PF16526.5 AAAP01001314.1_1 - 0.011 16.1 0.1 0.011 16.0 0.1 1.0 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapA PF05164.13 AAAP01001314.1_2 - 6.9e-24 84.1 1.5 1.1e-23 83.5 1.6 1.3 1 1 0 1 1 1 1 Cell division protein ZapA Ribosomal_L23 PF00276.20 AAAP01001315.1_1 - 9e-33 112.5 3.1 1e-32 112.4 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L4 PF00573.22 AAAP01001315.1_2 - 2.2e-64 216.7 0.5 2.5e-64 216.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Se-cys_synth_N PF12390.8 AAAP01001316.1_1 - 0.79 10.0 7.6 1 9.6 0.4 3.5 4 0 0 4 4 4 0 Selenocysteine synthase N terminal Sigma70_r2 PF04542.14 AAAP01001316.1_2 - 1.6e-05 24.6 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Sigma-70 region 2 Pyrid_ox_like PF16242.5 AAAP01001317.1_1 - 1.3e-54 183.9 0.0 1.5e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 AAAP01001317.1_1 - 9.4e-14 51.4 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 AAAP01001317.1_1 - 5.7e-05 23.1 0.3 9.4e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 AAAP01001317.1_1 - 0.018 14.7 0.0 0.052 13.3 0.0 1.6 1 1 1 2 2 2 0 Putative FMN-binding domain Abhydrolase_1 PF00561.20 AAAP01001317.1_3 - 2.4e-07 30.7 0.1 2.4e-07 30.7 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01001317.1_3 - 0.0026 17.1 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AAAP01001317.1_3 - 0.033 13.7 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Plug PF07715.15 AAAP01001318.1_1 - 5.8e-12 46.1 0.2 6.7e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Hydrolase_4 PF12146.8 AAAP01001319.1_2 - 4.9e-23 81.6 0.3 6.1e-23 81.3 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAAP01001319.1_2 - 4.9e-10 40.4 0.1 6.4e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01001319.1_2 - 1.5e-08 34.6 0.0 1.9e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAAP01001319.1_2 - 0.022 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thiolase_C PF02803.18 AAAP01001320.1_1 - 3.6e-46 155.8 0.1 4.1e-46 155.6 0.1 1.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 AAAP01001320.1_1 - 0.00085 19.5 0.1 0.0016 18.6 0.1 1.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2795 PF11387.8 AAAP01001321.1_2 - 0.019 15.2 0.2 0.044 14.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) CPBP PF02517.16 AAAP01001322.1_1 - 0.00013 22.3 2.9 0.00013 22.3 2.9 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease MerC PF03203.14 AAAP01001322.1_1 - 0.94 10.0 8.8 79 3.8 8.8 2.7 1 1 0 1 1 1 0 MerC mercury resistance protein Pyr_redox_2 PF07992.14 AAAP01001323.1_1 - 3.9e-27 95.3 0.7 2.2e-18 66.5 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01001323.1_1 - 2.1e-09 37.1 0.1 0.0055 16.0 0.0 3.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01001323.1_1 - 2.8e-08 33.9 1.5 3.1e-08 33.7 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AAAP01001323.1_1 - 3.4e-07 29.9 0.7 3.4e-07 29.9 0.7 3.1 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 AAAP01001323.1_1 - 7.2e-07 28.9 0.1 7.2e-07 28.9 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAAP01001323.1_1 - 7e-06 26.4 0.1 0.061 13.8 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 AAAP01001323.1_1 - 7.5e-06 26.4 0.7 0.012 16.2 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01001323.1_1 - 2e-05 23.9 1.5 2e-05 23.9 1.5 2.3 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 AAAP01001323.1_1 - 3.5e-05 22.7 2.2 6.2e-05 21.9 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FMO-like PF00743.19 AAAP01001323.1_1 - 3.9e-05 22.3 0.0 0.062 11.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 AAAP01001323.1_1 - 6.3e-05 22.7 1.4 6.3e-05 22.7 1.4 3.0 2 1 2 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAAP01001323.1_1 - 0.00017 21.0 0.5 0.00017 21.0 0.5 2.2 3 0 0 3 3 2 1 FAD binding domain Thi4 PF01946.17 AAAP01001323.1_1 - 0.00021 20.6 0.5 0.00045 19.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 AAAP01001323.1_1 - 0.00025 20.3 1.8 0.0036 16.4 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A YjeF_N PF03853.15 AAAP01001323.1_1 - 0.00046 20.1 0.2 0.81 9.6 0.0 2.3 2 0 0 2 2 2 2 YjeF-related protein N-terminus DJ-1_PfpI PF01965.24 AAAP01001323.1_1 - 0.0018 18.1 1.9 0.022 14.5 0.0 2.9 1 1 1 3 3 3 1 DJ-1/PfpI family Lycopene_cycl PF05834.12 AAAP01001323.1_1 - 0.0045 16.1 0.5 0.063 12.3 0.2 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AAAP01001323.1_1 - 0.0047 16.2 2.4 0.094 12.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAAP01001323.1_1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAAP01001323.1_1 - 0.021 14.9 1.7 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K_oxygenase PF13434.6 AAAP01001323.1_1 - 0.023 13.9 0.3 0.83 8.7 0.1 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 AAAP01001323.1_1 - 0.032 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AAAP01001323.1_1 - 0.033 14.8 0.0 2.5 8.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 AAAP01001323.1_1 - 0.046 13.7 3.7 0.38 10.7 0.1 3.4 3 1 0 4 4 4 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 AAAP01001323.1_1 - 0.048 13.0 1.0 0.18 11.1 0.0 2.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAAP01001323.1_1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AAAP01001323.1_1 - 0.19 11.8 0.1 8.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PK PF00224.21 AAAP01001323.1_2 - 1.5e-38 132.6 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain IMPDH PF00478.25 AAAP01001323.1_2 - 0.0041 16.2 0.2 0.0051 15.9 0.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF3710 PF12502.8 AAAP01001323.1_2 - 0.045 13.4 0.1 0.094 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3710) Maf PF02545.14 AAAP01001324.1_1 - 4.1e-05 23.5 0.0 4.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Usp PF00582.26 AAAP01001325.1_1 - 3.6e-09 37.3 0.0 1.6e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 Universal stress protein family DUF3040 PF11239.8 AAAP01001326.1_2 - 7.9 6.8 9.8 43 4.5 9.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Autotransporter PF03797.19 AAAP01001327.1_1 - 9.9e-43 146.6 15.5 2e-42 145.6 15.5 1.5 1 0 0 1 1 1 1 Autotransporter beta-domain TetR_C_11 PF16859.5 AAAP01001327.1_1 - 0.044 14.1 3.4 0.23 11.8 3.9 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NAD_binding_1 PF00175.21 AAAP01001328.1_1 - 4.9e-08 33.6 0.0 6.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain LysR_substrate PF03466.20 AAAP01001328.1_2 - 2.2e-23 82.8 6.0 2.4e-23 82.6 6.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain Uso1_p115_C PF04871.13 AAAP01001329.1_1 - 0.15 12.4 0.4 0.26 11.7 0.1 1.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CBM_48 PF02922.18 AAAP01001330.1_1 - 1.3e-19 70.3 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 AAAP01001330.1_1 - 3.3e-09 36.8 0.0 5.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 AAAP01001330.1_1 - 0.21 10.6 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain MTS PF05175.14 AAAP01001331.1_1 - 0.00011 21.8 0.0 0.00011 21.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAAP01001331.1_1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 AAAP01001331.1_1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 AAAP01001331.1_1 - 0.036 14.8 0.1 0.054 14.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 AAAP01001331.1_1 - 0.049 12.9 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 AAAP01001331.1_1 - 0.087 12.6 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase YqcI_YcgG PF08892.11 AAAP01001331.1_2 - 0.0099 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 YqcI/YcgG family Cupin_7 PF12973.7 AAAP01001332.1_1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Cupin_2 PF07883.11 AAAP01001332.1_1 - 0.081 12.7 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Cupin domain CBAH PF02275.18 AAAP01001333.1_1 - 2.5e-64 218.0 0.0 2.7e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family pP_pnuc_2 PF18166.1 AAAP01001334.1_1 - 1e-14 54.6 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Predicted pPIWI-associating nuclease FRG PF08867.11 AAAP01001334.1_2 - 1.7e-14 54.5 0.1 2.3e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 FRG domain DUF5428 PF17493.2 AAAP01001335.1_2 - 0.077 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5428) TP_methylase PF00590.20 AAAP01001337.1_1 - 6.4e-17 62.2 0.0 7.6e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.20 AAAP01001337.1_2 - 1.2e-18 67.8 1.8 1.5e-18 67.5 1.8 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF900 PF05990.12 AAAP01001338.1_1 - 1.3e-10 41.2 0.1 1.8e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 AAAP01001339.1_1 - 1.1e-12 48.2 0.0 3.9e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01001339.1_1 - 4.6e-11 43.7 6.5 5.6e-11 43.5 6.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01001339.1_1 - 1.7e-07 30.8 0.1 5e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAAP01001339.1_1 - 1.7e-06 28.3 0.0 2.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 AAAP01001339.1_1 - 0.00023 21.2 0.0 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 AAAP01001339.1_1 - 0.0014 18.4 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 AAAP01001339.1_1 - 0.0041 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 AAAP01001339.1_1 - 0.021 14.7 0.3 0.095 12.5 0.3 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 AAAP01001339.1_1 - 0.034 13.7 0.0 0.13 11.8 0.0 1.7 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 AAAP01001339.1_1 - 0.062 12.8 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family GFA PF04828.14 AAAP01001340.1_1 - 0.0018 18.6 1.8 0.0018 18.6 1.8 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HCV_env PF01539.17 AAAP01001340.1_1 - 0.045 13.4 1.0 0.043 13.5 1.0 1.0 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 SDF PF00375.18 AAAP01001340.1_2 - 1e-05 24.8 0.1 1.1e-05 24.6 0.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family tRNA_edit PF04073.15 AAAP01001340.1_2 - 0.045 13.8 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain ABC_membrane PF00664.23 AAAP01001341.1_1 - 1.5e-07 31.4 1.7 1.9e-07 31.0 1.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4912 PF16258.5 AAAP01001341.1_1 - 0.015 15.5 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) SUKH-4 PF14435.6 AAAP01001341.1_2 - 0.035 14.2 0.3 0.074 13.1 0.2 1.6 1 1 0 1 1 1 0 SUKH-4 immunity protein AMP-binding_C PF13193.6 AAAP01001342.1_1 - 2.5e-23 82.8 0.3 4.6e-23 82.0 0.3 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AAAP01001342.1_1 - 4.1e-10 38.8 2.2 5.9e-10 38.3 2.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme CAP PF00188.26 AAAP01001342.1_2 - 0.021 15.7 0.0 0.024 15.5 0.0 1.1 1 0 0 1 1 1 0 Cysteine-rich secretory protein family PhoH PF02562.16 AAAP01001343.1_1 - 3.9e-41 140.8 0.0 4.7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AAAP01001343.1_1 - 8.1e-05 22.4 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 AAAP01001343.1_1 - 0.0015 18.1 0.1 0.002 17.7 0.1 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 AAAP01001343.1_1 - 0.0046 17.4 0.0 0.0061 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAAP01001343.1_1 - 0.0071 16.3 0.1 0.049 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AAAP01001343.1_1 - 0.0081 16.5 0.2 0.0083 16.5 0.2 1.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAAP01001343.1_1 - 0.0097 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 AAAP01001343.1_1 - 0.075 12.6 0.1 0.2 11.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 AAAP01001343.1_1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 AAAP01001343.1_1 - 0.092 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 AAAP01001343.1_1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 AAAP01001343.1_1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 AAAP01001343.1_1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAAP01001343.1_1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 AAAP01001343.1_1 - 0.24 10.5 0.0 1.4 8.0 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase IstB_IS21 PF01695.17 AAAP01001345.1_1 - 7.7e-18 64.8 0.0 8.9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein eIF-1a PF01176.19 AAAP01001346.1_1 - 1.1e-10 41.2 0.0 1.3e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 GvpO PF05800.11 AAAP01001346.1_1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Peripla_BP_6 PF13458.6 AAAP01001346.1_2 - 2e-05 24.4 0.0 2e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Virul_fac_BrkB PF03631.15 AAAP01001347.1_1 - 2.5e-21 76.5 0.5 3e-21 76.2 0.5 1.1 1 0 0 1 1 1 1 Virulence factor BrkB PTS_EIIB PF00367.20 AAAP01001348.1_1 - 1.6e-13 49.9 0.0 2.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 phosphotransferase system, EIIB MS_channel PF00924.18 AAAP01001348.1_2 - 8.3e-06 25.5 0.0 9.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel ERAP1_C PF11838.8 AAAP01001349.1_1 - 8.1e-21 74.9 1.4 9.8e-21 74.6 1.4 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain FGE-sulfatase PF03781.16 AAAP01001350.1_1 - 2.8e-73 246.7 1.4 3.3e-73 246.5 1.4 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Glyco_transf_4 PF13439.6 AAAP01001351.1_1 - 0.011 15.7 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01001351.1_1 - 0.014 15.9 0.1 0.016 15.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain AP_endonuc_2 PF01261.24 AAAP01001351.1_2 - 1.1e-25 90.3 0.2 1.6e-25 89.8 0.2 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SAF PF08666.12 AAAP01001351.1_2 - 0.035 14.7 0.2 2 9.1 0.0 2.8 3 0 0 3 3 3 0 SAF domain UvrD_C_2 PF13538.6 AAAP01001352.1_1 - 9.3e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 AAAP01001352.1_1 - 0.061 12.7 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3363 PF11843.8 AAAP01001354.1_1 - 2.7e-36 125.3 5.0 1.3e-33 116.5 0.1 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3363) MobL PF18555.1 AAAP01001354.1_1 - 0.00049 19.5 0.1 0.00068 19.0 0.1 1.3 1 0 0 1 1 1 1 MobL relaxases Relaxase PF03432.14 AAAP01001354.1_1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain HrpE PF06188.12 AAAP01001354.1_1 - 0.041 13.8 0.1 0.09 12.6 0.1 1.5 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DcrB PF08786.11 AAAP01001354.1_1 - 0.085 13.0 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 DcrB Polyoma_coat2 PF00761.20 AAAP01001354.1_1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein HTH_29 PF13551.6 AAAP01001356.1_1 - 3.6e-13 49.3 1.1 3.6e-13 49.3 0.2 1.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01001356.1_1 - 2e-11 43.4 0.2 3.7e-11 42.5 0.1 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01001356.1_1 - 1.3e-08 34.9 1.1 1.5e-08 34.6 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 AAAP01001356.1_1 - 3.9e-08 33.8 1.9 1.1e-06 29.2 0.1 2.4 1 1 1 2 2 2 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 AAAP01001356.1_1 - 2.7e-06 27.8 0.4 3.9e-06 27.3 0.4 1.4 1 1 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 AAAP01001356.1_1 - 1.9e-05 24.9 0.0 4.9e-05 23.5 0.0 1.6 1 1 1 2 2 2 1 Transposase GerE PF00196.19 AAAP01001356.1_1 - 0.00085 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01001356.1_1 - 0.002 17.8 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Terminase_5 PF06056.12 AAAP01001356.1_1 - 0.008 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) AAA_25 PF13481.6 AAAP01001358.1_1 - 2.9e-08 33.5 2.7 1.6e-07 31.1 1.4 2.6 2 2 0 2 2 2 1 AAA domain Isochorismatase PF00857.20 AAAP01001358.1_1 - 0.0059 16.8 0.0 0.009 16.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family ATPase PF06745.13 AAAP01001358.1_1 - 0.007 15.7 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 1 KaiC RTP1_C2 PF10304.9 AAAP01001358.1_1 - 0.0082 15.8 0.1 0.025 14.2 0.1 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 dCMP_cyt_deam_1 PF00383.23 AAAP01001359.1_1 - 3.8e-17 62.0 0.0 5.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAAP01001359.1_1 - 7.9e-16 58.1 0.0 9.8e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 AAAP01001359.1_1 - 0.0069 16.5 0.0 0.0092 16.1 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 DUF4388 PF14332.6 AAAP01001359.1_1 - 0.027 14.7 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) APOBEC3 PF18771.1 AAAP01001359.1_1 - 0.058 13.5 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 AAAP01001359.1_1 - 0.13 12.3 0.9 0.45 10.6 0.9 1.7 1 1 1 2 2 2 0 Bd3614-like deaminase APOBEC2 PF18772.1 AAAP01001359.1_1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 ETC_C1_NDUFA4 PF04800.12 AAAP01001359.1_2 - 3.4e-16 59.3 0.0 3.7e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region GST_N PF02798.20 AAAP01001359.1_3 - 1.9e-09 37.8 0.0 2.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01001359.1_3 - 3.9e-08 33.5 0.0 4.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAAP01001359.1_3 - 5.9e-08 33.0 0.0 7.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4352 PF11611.8 AAAP01001360.1_2 - 0.064 13.5 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) MFS_1 PF07690.16 AAAP01001361.1_1 - 4.3e-08 32.5 54.9 1.8e-05 23.9 19.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B_2 PF12706.7 AAAP01001363.1_1 - 8.7e-07 28.6 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4926 PF16277.5 AAAP01001363.1_2 - 0.056 12.8 0.2 0.074 12.4 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4926) Desulfoferrod_N PF06397.12 AAAP01001363.1_2 - 0.22 11.2 0.2 0.26 10.9 0.1 1.3 1 1 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain HMGL-like PF00682.19 AAAP01001364.1_1 - 4.1e-36 124.9 1.1 4.9e-36 124.6 1.1 1.0 1 0 0 1 1 1 1 HMGL-like DUF3376 PF11856.8 AAAP01001364.1_1 - 0.0051 15.9 0.3 0.0054 15.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) Gloverin PF10793.9 AAAP01001365.1_1 - 0.068 13.0 2.0 0.076 12.9 1.9 1.3 1 1 0 1 1 1 0 Gloverin-like protein Fer4 PF00037.27 AAAP01001366.1_1 - 1.4e-08 34.2 22.9 2.7e-07 30.1 6.1 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01001366.1_1 - 1.3e-07 31.7 25.1 2.3e-05 24.5 14.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01001366.1_1 - 2.9e-07 31.3 9.2 0.00012 22.9 0.7 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01001366.1_1 - 2.2e-06 28.2 15.6 5.9e-06 26.8 15.6 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01001366.1_1 - 4.3e-06 26.7 26.7 0.00066 19.7 15.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01001366.1_1 - 5.5e-06 26.2 19.4 0.00041 20.3 4.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01001366.1_1 - 8.9e-05 22.4 13.6 0.0083 16.2 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01001366.1_1 - 0.00023 21.5 8.2 0.0042 17.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01001366.1_1 - 0.00026 21.3 16.4 0.0013 19.1 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01001366.1_1 - 0.00074 20.0 12.2 0.013 16.0 2.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01001366.1_1 - 0.0018 18.3 17.5 0.0038 17.3 2.3 2.2 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01001366.1_1 - 1.7 9.8 20.6 0.85 10.7 7.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Mqo PF06039.15 AAAP01001367.1_1 - 6.4e-126 420.8 0.0 7.7e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) SH3_16 PF18348.1 AAAP01001368.1_1 - 7.2e-19 67.3 0.4 2.2e-18 65.8 0.4 1.9 1 0 0 1 1 1 1 Bacterial dipeptidyl-peptidase Sh3 domain NLPC_P60 PF00877.19 AAAP01001368.1_1 - 7.9e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.11 AAAP01001368.1_1 - 0.00039 20.6 0.0 0.0019 18.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain PMSR PF01625.21 AAAP01001369.1_1 - 4.2e-63 212.1 1.1 5e-63 211.9 1.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase adh_short_C2 PF13561.6 AAAP01001369.1_2 - 3.2e-11 43.3 0.0 3.2e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACR_tran PF00873.19 AAAP01001370.1_1 - 6.5e-70 236.0 0.4 7.2e-70 235.8 0.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ACR_tran PF00873.19 AAAP01001372.1_1 - 1.9e-30 105.4 0.0 2.1e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Laminin_G_3 PF13385.6 AAAP01001373.1_1 - 3.4e-19 69.5 1.5 3.4e-19 69.5 1.5 2.1 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_43 PF04616.14 AAAP01001373.1_1 - 5.1e-19 68.7 0.4 8.1e-19 68.0 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5018 PF16410.5 AAAP01001373.1_1 - 9.5e-07 27.8 0.1 1.4e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5018) MacB_PCD PF12704.7 AAAP01001374.1_1 - 6.5e-12 46.2 5.7 6.5e-12 46.2 5.7 1.7 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AAAP01001374.1_1 - 4.5e-07 30.2 1.7 4.5e-07 30.2 1.7 3.2 3 0 0 3 3 3 2 FtsX-like permease family NapE PF06796.11 AAAP01001374.1_1 - 0.061 12.9 0.6 0.16 11.5 0.6 1.7 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE MR_MLE_N PF02746.16 AAAP01001375.1_1 - 0.0017 18.6 0.1 0.0018 18.5 0.1 1.1 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1611 PF07755.11 AAAP01001375.1_2 - 1.3e-22 80.1 0.0 1.5e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1611_C) P-loop domain DUF1611 PF07755.11 AAAP01001375.1_3 - 6.3e-18 64.8 0.0 7.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1611_C) P-loop domain NMT1 PF09084.11 AAAP01001376.1_1 - 2.5e-10 40.7 0.0 3.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AAAP01001376.1_1 - 2.6e-08 33.6 0.0 3.1e-07 30.1 0.0 2.0 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 AAAP01001376.1_1 - 8.6e-08 32.2 0.6 1.3e-07 31.6 0.6 1.2 1 0 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 AAAP01001376.1_1 - 6.3e-07 29.2 0.2 7.9e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAAP01001376.1_1 - 2.7e-05 23.8 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01001376.1_1 - 0.00051 19.7 0.2 0.00065 19.4 0.2 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Peptidase_M17 PF00883.21 AAAP01001377.1_1 - 1.8e-39 135.9 0.0 2.7e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AAAP01001377.1_1 - 9.8e-19 67.5 1.5 2.2e-18 66.3 0.2 2.0 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain GATase PF00117.28 AAAP01001378.1_2 - 7.3e-49 166.1 1.6 1.1e-48 165.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01001378.1_2 - 1.5e-09 38.0 0.6 3.6e-09 36.7 0.6 1.6 1 0 0 1 1 1 1 Peptidase C26 CobU PF02283.16 AAAP01001378.1_2 - 6 6.4 10.1 37 3.8 8.8 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Extensin-like_C PF06904.12 AAAP01001379.1_2 - 4.3e-45 153.9 0.0 5.1e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Extensin-like protein C-terminus Peptidase_M15_4 PF13539.6 AAAP01001379.1_2 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF1887 PF09002.11 AAAP01001379.1_2 - 0.23 10.1 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Cys_Met_Meta_PP PF01053.20 AAAP01001380.1_1 - 1.5e-85 287.1 0.0 1.8e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01001380.1_1 - 2e-05 24.1 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAAP01001380.1_1 - 0.003 16.9 0.0 0.0068 15.7 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAAP01001380.1_1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DEDD_Tnp_IS110 PF01548.17 AAAP01001380.1_1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Transposase PUCC PF03209.15 AAAP01001381.1_1 - 2.7e-17 62.9 3.6 2.9e-17 62.8 3.6 1.0 1 0 0 1 1 1 1 PUCC protein FANC_SAP PF18081.1 AAAP01001381.1_1 - 0.03 14.5 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain PRCH PF03967.13 AAAP01001381.1_2 - 7e-52 175.1 0.0 1e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Photosynthetic reaction centre, H-chain N-terminal region PRC PF05239.16 AAAP01001381.1_2 - 4.6e-08 33.0 0.0 8.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 PRC-barrel domain CPSase_L_D2 PF02786.17 AAAP01001382.1_1 - 9.8e-68 227.8 0.5 2.4e-66 223.3 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 AAAP01001382.1_1 - 0.001 18.7 0.0 0.0033 17.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 AAAP01001382.1_1 - 0.037 13.8 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon AMP-binding_C PF13193.6 AAAP01001383.1_2 - 0.00053 20.9 0.0 0.0009 20.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AAAP01001383.1_2 - 0.0049 15.5 0.0 0.0058 15.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_5 PF07994.12 AAAP01001385.1_2 - 1.2e-26 93.8 1.0 2.2e-21 76.6 0.0 2.0 1 1 1 2 2 2 2 Myo-inositol-1-phosphate synthase Methyltransf_11 PF08241.12 AAAP01001386.1_1 - 2.9e-07 31.0 0.0 4.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01001386.1_1 - 8.6e-07 28.9 0.0 1.6e-06 28.1 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01001386.1_1 - 6.1e-06 26.9 0.0 8.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01001386.1_1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01001386.1_1 - 0.15 12.8 0.0 0.4 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain HlyD PF00529.20 AAAP01001387.1_1 - 0.0028 17.5 2.1 0.041 13.8 2.1 2.2 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_D23 PF16576.5 AAAP01001387.1_1 - 0.0068 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01001387.1_1 - 0.031 15.0 0.1 0.057 14.1 0.1 1.5 1 1 0 1 1 1 0 HlyD family secretion protein BatD PF13584.6 AAAP01001387.1_2 - 4.1e-12 45.7 0.1 8.7e-12 44.6 0.1 1.6 1 1 0 1 1 1 1 Oxygen tolerance DUF4381 PF14316.6 AAAP01001387.1_2 - 0.0057 16.9 3.8 0.012 15.8 3.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4381) Tad PF13400.6 AAAP01001387.1_2 - 0.65 10.4 7.5 1.3 9.3 4.0 2.7 2 1 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF4190 PF13828.6 AAAP01001389.1_1 - 1.3e-07 31.3 5.4 1.3e-07 31.3 5.4 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4190) Syndecan PF01034.20 AAAP01001389.1_1 - 0.28 11.1 1.6 0.39 10.7 1.6 1.2 1 0 0 1 1 1 0 Syndecan domain DUF2752 PF10825.8 AAAP01001389.1_2 - 1.6e-20 72.9 5.0 4.9e-20 71.3 5.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) DUF3487 PF11990.8 AAAP01001389.1_2 - 0.19 11.6 3.7 0.17 11.8 0.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3487) IGPS PF00218.21 AAAP01001389.1_3 - 2.6e-68 230.0 0.0 2.8e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 AAAP01001389.1_3 - 0.0013 17.9 0.4 0.025 13.7 0.2 2.4 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 AAAP01001389.1_3 - 0.039 13.4 0.1 2.9 7.3 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein PIN PF01850.21 AAAP01001390.1_2 - 1.9e-13 51.0 0.0 2.1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 PIN domain Fer4_20 PF14691.6 AAAP01001390.1_3 - 0.0012 18.6 0.1 0.0015 18.3 0.1 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster zf-C2HC5 PF06221.13 AAAP01001390.1_3 - 0.037 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF1045 PF06299.12 AAAP01001390.1_3 - 0.077 13.0 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Peptidase_M23 PF01551.22 AAAP01001391.1_1 - 4.5e-10 39.6 0.8 9.6e-10 38.5 0.8 1.5 1 0 0 1 1 1 1 Peptidase family M23 CoA_transf_3 PF02515.17 AAAP01001391.1_2 - 1.5e-05 24.3 0.1 2.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CoA-transferase family III ABC_tran PF00005.27 AAAP01001393.1_1 - 2.3e-30 105.9 0.0 3.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01001393.1_1 - 7.4e-05 23.2 0.1 0.0001 22.7 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAAP01001393.1_1 - 9.5e-05 21.9 0.0 0.42 10.0 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAAP01001393.1_1 - 0.00028 20.8 0.0 0.0091 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01001393.1_1 - 0.00031 21.0 0.0 0.0007 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01001393.1_1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01001393.1_1 - 0.0026 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 AAAP01001393.1_1 - 0.0052 16.4 0.1 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAAP01001393.1_1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 AAAP01001393.1_1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 AAAP01001393.1_1 - 0.016 14.6 0.0 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 AAAP01001393.1_1 - 0.024 14.8 0.0 0.067 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01001393.1_1 - 0.031 14.0 0.4 0.088 12.5 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 AAAP01001393.1_1 - 0.037 14.5 0.0 0.054 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAAP01001393.1_1 - 0.055 12.3 0.1 7.2 5.3 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 AAAP01001393.1_1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 AAAP01001393.1_1 - 0.13 12.5 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AAAP01001393.1_1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain DLIC PF05783.11 AAAP01001393.1_1 - 0.21 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) YCII PF03795.14 AAAP01001394.1_1 - 0.0028 18.0 0.5 0.0063 16.9 0.5 1.5 1 1 0 1 1 1 1 YCII-related domain zf-CDGSH PF09360.10 AAAP01001394.1_1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Iron-binding zinc finger CDGSH type UreE_N PF02814.15 AAAP01001395.1_1 - 3.3e-13 49.0 2.8 5.8e-13 48.2 2.8 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.12 AAAP01001395.1_1 - 4.3e-05 23.9 67.3 53 4.4 63.9 3.7 2 1 0 2 2 2 1 UreE urease accessory protein, C-terminal domain DUF3293 PF11697.8 AAAP01001395.1_2 - 0.094 13.2 0.0 0.099 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) Cytochrome_CBB3 PF13442.6 AAAP01001396.1_2 - 1.3e-15 57.4 0.0 1.9e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01001396.1_2 - 0.0014 19.8 0.3 0.021 16.0 0.3 2.2 1 1 0 1 1 1 1 Cytochrome c LGT PF01790.18 AAAP01001397.1_1 - 1.1e-24 87.1 0.4 1.3e-24 86.8 0.4 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Trp_syntA PF00290.20 AAAP01001397.1_2 - 6.3e-66 221.9 0.0 7.8e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain BtpA PF03437.15 AAAP01001397.1_2 - 0.003 17.0 0.1 0.0067 15.9 0.1 1.6 2 0 0 2 2 2 1 BtpA family PcrB PF01884.17 AAAP01001397.1_2 - 0.0065 15.9 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 PcrB family PGM_PMM_III PF02880.16 AAAP01001398.1_2 - 1.8e-32 111.9 0.0 4e-32 110.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AAAP01001398.1_2 - 4.1e-15 55.7 0.5 1e-14 54.5 0.5 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 AAAP01001398.1_2 - 7.6e-10 39.3 0.0 2.3e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Pyr_redox_2 PF07992.14 AAAP01001399.1_1 - 6.8e-58 196.2 5.8 8.2e-58 195.9 5.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01001399.1_1 - 7e-16 58.3 13.8 1.6e-13 50.6 2.8 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AAAP01001399.1_1 - 1.4e-14 54.1 0.1 1.7e-13 50.5 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01001399.1_1 - 2.8e-14 53.4 3.6 9.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAAP01001399.1_1 - 5.3e-08 32.6 11.1 4e-07 29.8 4.6 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AAAP01001399.1_1 - 5.7e-05 22.4 0.6 0.0074 15.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AAAP01001399.1_1 - 6.4e-05 21.8 1.9 6.4e-05 21.8 1.9 2.8 3 1 1 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.24 AAAP01001399.1_1 - 0.00024 20.3 18.3 0.019 14.1 16.6 3.5 1 1 1 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 AAAP01001399.1_1 - 0.00055 19.9 6.6 0.024 14.5 0.4 2.6 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAAP01001399.1_1 - 0.00062 20.2 1.4 0.34 11.4 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 AAAP01001399.1_1 - 0.0034 16.7 1.0 0.0034 16.7 1.0 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 AAAP01001399.1_1 - 0.0093 15.3 8.9 0.025 13.9 1.3 2.9 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain DFP PF04127.15 AAAP01001399.1_1 - 0.017 15.0 3.4 2.4 8.0 0.8 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein FAD_binding_3 PF01494.19 AAAP01001399.1_1 - 0.05 12.8 9.4 0.21 10.8 0.6 3.0 3 0 0 3 3 3 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01001399.1_1 - 0.093 12.3 4.9 0.25 10.9 0.3 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 AAAP01001399.1_1 - 0.14 11.2 7.1 0.17 10.9 0.5 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 AAAP01001399.1_1 - 0.15 11.7 17.6 0.69 9.4 6.6 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 AAAP01001399.1_1 - 0.24 11.4 3.1 13 5.7 0.9 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 AAAP01001399.1_1 - 0.88 10.1 3.7 1.1 9.7 0.1 2.5 2 2 0 2 2 2 0 XdhC Rossmann domain ApbA PF02558.16 AAAP01001399.1_1 - 1.6 8.4 7.8 2.4 7.8 0.5 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 AAAP01001399.1_1 - 2 8.7 13.4 0.092 13.0 3.0 2.8 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AAAP01001399.1_1 - 3.4 6.4 7.2 0.51 9.1 1.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.19 AAAP01001399.1_1 - 4.9 6.5 5.4 3.3 7.0 0.2 2.8 3 1 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF563 PF04577.14 AAAP01001400.1_1 - 1.1e-28 100.8 0.0 1.3e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Mac PF12464.8 AAAP01001400.1_1 - 0.16 12.3 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Maltose acetyltransferase Rubredoxin_2 PF18073.1 AAAP01001400.1_1 - 0.72 9.6 6.6 11 5.9 4.8 2.9 2 1 0 2 2 2 0 Rubredoxin metal binding domain tRNA_U5-meth_tr PF05958.11 AAAP01001400.1_2 - 0.14 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Oxidored_q6 PF01058.22 AAAP01001402.1_2 - 2e-23 82.7 0.1 2.7e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 AAAP01001402.1_2 - 0.16 11.8 3.1 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 Honey bee peptides TetR_N PF00440.23 AAAP01001403.1_1 - 1.3e-12 47.3 0.4 1.3e-12 47.3 0.4 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 AAAP01001403.1_1 - 4.9e-05 23.0 3.1 0.00011 22.0 0.0 2.8 3 1 0 3 3 3 1 IclR helix-turn-helix domain HTH_3 PF01381.22 AAAP01001403.1_1 - 0.0061 16.6 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_7 PF02796.15 AAAP01001403.1_1 - 0.018 15.1 0.0 0.083 13.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Phage_AlpA PF05930.12 AAAP01001403.1_1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_23 PF13384.6 AAAP01001403.1_1 - 0.091 12.6 2.0 0.22 11.4 0.1 2.5 3 0 0 3 3 3 0 Homeodomain-like domain REF PF05755.12 AAAP01001403.1_1 - 1.1 9.0 5.4 0.81 9.5 4.1 1.4 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) RecO_N PF11967.8 AAAP01001403.1_2 - 1.8e-29 101.5 0.0 2.8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Recombination protein O N terminal RecO_C PF02565.15 AAAP01001403.1_2 - 5.5e-22 78.2 0.6 6.9e-22 77.9 0.6 1.1 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N_2 PF13114.6 AAAP01001403.1_2 - 0.00033 20.3 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 RecO N terminal Zn_Tnp_IS1595 PF12760.7 AAAP01001403.1_2 - 0.36 10.8 2.0 0.86 9.6 2.0 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Peripla_BP_3 PF13377.6 AAAP01001406.1_1 - 7.9e-34 117.4 0.2 9.5e-33 113.9 0.2 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAAP01001406.1_1 - 1.1e-21 77.6 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 AAAP01001406.1_1 - 2.3e-15 56.1 0.1 5.2e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 AAAP01001406.1_1 - 7e-10 38.9 0.0 6.4e-08 32.5 0.0 2.6 2 1 0 2 2 2 1 Periplasmic binding protein domain HTH_31 PF13560.6 AAAP01001406.1_1 - 0.00036 20.8 0.4 0.0017 18.7 0.4 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01001406.1_1 - 0.019 14.7 0.1 1.2 9.0 0.0 3.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_3 PF01381.22 AAAP01001406.1_1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_10 PF04967.12 AAAP01001406.1_1 - 0.18 11.6 0.1 3.7 7.4 0.0 2.6 3 0 0 3 3 3 0 HTH DNA binding domain DUF4096 PF13340.6 AAAP01001407.1_2 - 8.3e-15 54.8 0.2 1e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) BaxI_1 PF12811.7 AAAP01001408.1_1 - 0.062 12.9 6.3 0.086 12.4 6.3 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF3995 PF13160.6 AAAP01001408.1_1 - 0.19 12.1 9.8 0.18 12.2 8.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) DUF4690 PF15756.5 AAAP01001408.1_1 - 0.59 10.8 0.0 0.59 10.8 0.0 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage TRP PF06011.12 AAAP01001408.1_1 - 0.74 8.5 8.8 0.33 9.6 7.0 1.3 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel ACR_tran PF00873.19 AAAP01001410.1_1 - 1.2e-81 274.8 0.1 1.5e-81 274.6 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF4539 PF15072.6 AAAP01001410.1_1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) AAA_5 PF07728.14 AAAP01001411.1_1 - 0.00039 20.4 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 AAAP01001411.1_1 - 0.051 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF885 PF05960.11 AAAP01001412.1_1 - 0.01 15.5 0.3 0.011 15.4 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ApoLp-III PF07464.11 AAAP01001412.1_1 - 0.065 13.3 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Amidohydro_1 PF01979.20 AAAP01001413.1_1 - 0.00083 18.8 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AAAP01001413.1_1 - 0.0022 18.3 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain GCV_T PF01571.21 AAAP01001413.1_2 - 4.4e-10 39.3 0.0 5e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain NIR_SIR PF01077.22 AAAP01001413.1_2 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain CBP_BcsQ PF06564.12 AAAP01001414.1_1 - 8.3e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AAAP01001414.1_1 - 0.00025 20.4 0.1 0.0003 20.2 0.1 1.1 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 AAAP01001414.1_1 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain GT87 PF09594.10 AAAP01001415.1_1 - 3.3e-05 23.7 39.0 3.3e-05 23.7 39.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 87 PMT PF02366.18 AAAP01001415.1_1 - 0.0015 18.2 4.5 0.0015 18.2 4.5 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Peripla_BP_2 PF01497.18 AAAP01001416.1_2 - 3.1e-18 66.2 0.1 3.6e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein IF-2B PF01008.17 AAAP01001417.1_1 - 1.4e-39 136.1 0.0 1.8e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family HAP2-GCS1 PF10699.9 AAAP01001417.1_1 - 0.0094 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Male gamete fusion factor HATPase_c PF02518.26 AAAP01001418.1_1 - 1e-17 64.7 0.1 1.5e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01001418.1_1 - 4.1e-12 45.9 0.2 4.1e-12 45.9 0.2 2.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain TPR_1 PF00515.28 AAAP01001419.1_1 - 1.6e-41 138.4 14.9 3.3e-08 33.0 0.1 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01001419.1_1 - 2.4e-40 133.4 18.3 1.4e-07 31.1 0.0 6.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01001419.1_1 - 1e-38 130.7 19.5 1.3e-09 37.5 0.3 6.3 2 2 4 6 6 6 6 TPR repeat TPR_8 PF13181.6 AAAP01001419.1_1 - 6.4e-31 104.0 9.2 5.4e-07 29.3 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01001419.1_1 - 3.5e-30 102.2 13.8 5.5e-05 23.3 0.2 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01001419.1_1 - 3.1e-24 84.9 11.2 3e-07 30.5 1.3 4.8 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01001419.1_1 - 1.8e-22 79.7 40.2 1.1e-07 32.4 1.0 3.9 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01001419.1_1 - 7e-21 73.1 16.5 0.00084 20.0 0.2 6.9 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01001419.1_1 - 1.2e-16 60.8 20.3 3.5e-07 30.4 0.8 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01001419.1_1 - 5.4e-15 55.7 17.6 2.1e-05 25.0 2.0 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01001419.1_1 - 1.3e-13 50.6 12.6 0.29 11.9 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01001419.1_1 - 1.9e-11 43.2 10.2 0.067 13.2 0.3 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01001419.1_1 - 2.9e-11 43.1 12.0 0.0053 16.0 1.7 4.6 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01001419.1_1 - 2.8e-08 33.4 27.9 0.0001 22.1 0.4 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 AAAP01001419.1_1 - 3.4e-06 27.6 7.6 0.0077 16.7 0.0 3.1 2 1 0 2 2 2 2 Bacterial transcriptional activator domain NARP1 PF12569.8 AAAP01001419.1_1 - 1.5e-05 24.1 1.9 0.021 13.8 0.0 3.3 1 1 3 4 4 4 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.9 AAAP01001419.1_1 - 5.5e-05 22.5 0.1 1.1 8.8 0.0 3.8 3 0 0 3 3 3 2 SHNi-TPR TPR_20 PF14561.6 AAAP01001419.1_1 - 0.00016 22.0 9.9 0.12 12.8 0.1 4.4 1 1 5 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01001419.1_1 - 0.0009 19.4 2.6 0.44 10.8 0.5 3.4 1 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 AAAP01001419.1_1 - 0.00093 19.3 4.9 1.3 9.1 0.5 3.9 2 2 0 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 AAAP01001419.1_1 - 0.0083 15.8 18.8 0.065 12.9 6.5 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat-like domain PPTA PF01239.22 AAAP01001419.1_1 - 0.0087 15.8 1.8 4.6 7.1 0.0 3.9 5 0 0 5 5 5 1 Protein prenyltransferase alpha subunit repeat TPR_MalT PF17874.1 AAAP01001419.1_1 - 0.059 12.7 6.4 28 3.9 0.4 3.3 1 1 0 2 2 2 0 MalT-like TPR region EST1_DNA_bind PF10373.9 AAAP01001419.1_1 - 0.28 10.6 4.2 3.7 6.9 0.2 2.6 3 0 0 3 3 3 0 Est1 DNA/RNA binding domain DUF5113 PF17140.4 AAAP01001419.1_1 - 0.6 9.9 5.1 21 4.9 0.2 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) MIT PF04212.18 AAAP01001419.1_1 - 0.82 9.8 8.0 15 5.7 1.6 3.9 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 AAAP01001419.1_1 - 3 8.7 25.2 4.1 8.3 0.4 5.9 6 1 1 7 7 6 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 AAAP01001420.1_1 - 1.9e-06 27.4 0.1 2.7e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAAP01001420.1_1 - 7.7e-05 22.4 7.6 0.0013 18.3 1.9 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01001420.1_1 - 0.0016 18.6 0.3 0.0029 17.8 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01001420.1_1 - 0.0018 17.6 0.4 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAAP01001420.1_1 - 0.0073 15.2 0.2 2.3 7.0 0.2 2.0 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 AAAP01001420.1_1 - 0.014 14.5 1.4 0.39 9.7 0.6 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAAP01001420.1_1 - 0.028 14.4 1.8 0.35 10.9 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 AAAP01001420.1_1 - 0.034 12.9 0.1 0.86 8.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NIR_SIR PF01077.22 AAAP01001421.1_1 - 1.1e-13 51.0 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01001421.1_1 - 4e-13 49.0 0.0 1.6e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Sel_put PF04328.13 AAAP01001423.1_1 - 4.4e-17 61.9 0.0 7.1e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Selenoprotein, putative CstA_5TM PF13722.6 AAAP01001423.1_2 - 1.4e-13 51.2 0.8 1.4e-13 51.2 0.8 1.7 2 0 0 2 2 2 1 5TM C-terminal transporter carbon starvation CstA DUF4870 PF09685.10 AAAP01001423.1_2 - 0.087 12.9 2.3 0.35 11.0 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4870) CYYR1 PF10873.8 AAAP01001423.1_2 - 0.28 11.6 1.2 12 6.3 0.1 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF4131 PF13567.6 AAAP01001423.1_2 - 0.73 9.5 2.5 0.97 9.1 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4142 PF13628.6 AAAP01001424.1_1 - 1.3e-11 44.9 0.3 2e-11 44.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) Acyl_transf_3 PF01757.22 AAAP01001424.1_2 - 0.0014 17.8 2.1 0.0016 17.6 2.1 1.0 1 0 0 1 1 1 1 Acyltransferase family Prim_Zn_Ribbon PF08273.12 AAAP01001425.1_2 - 1.3e-17 63.7 10.5 2.2e-17 63.0 10.5 1.3 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Toprim_3 PF13362.6 AAAP01001425.1_2 - 1.7e-06 28.3 0.0 4.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-RRN7 PF11781.8 AAAP01001425.1_2 - 0.00026 20.6 5.0 0.00084 19.0 5.0 1.8 1 1 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 AAAP01001425.1_2 - 0.00057 19.3 0.7 0.00096 18.6 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 AAAP01001425.1_2 - 0.00062 19.7 2.3 0.0014 18.6 2.0 1.7 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 AAAP01001425.1_2 - 0.0077 16.6 0.3 0.013 15.8 0.3 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar Cys_rich_KTR PF14205.6 AAAP01001425.1_2 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR Nudix_N_2 PF14803.6 AAAP01001425.1_2 - 0.13 12.2 2.3 0.36 10.8 2.3 1.8 1 0 0 1 1 1 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 AAAP01001425.1_2 - 0.15 12.0 0.9 0.28 11.1 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 AAAP01001425.1_2 - 0.61 10.2 3.5 9.6 6.4 1.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-FPG_IleRS PF06827.14 AAAP01001425.1_2 - 3.1 7.8 5.7 42 4.1 5.7 2.2 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS DDE_Tnp_1 PF01609.21 AAAP01001426.1_1 - 1.2e-06 28.3 0.1 1.7e-06 27.8 0.1 1.4 1 1 0 1 1 1 1 Transposase DDE domain DUF4164 PF13747.6 AAAP01001426.1_1 - 0.0017 18.6 4.1 0.024 14.9 3.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Ead_Ea22 PF13935.6 AAAP01001426.1_1 - 0.18 12.5 3.6 0.25 12.0 3.2 1.3 1 1 0 1 1 1 0 Ead/Ea22-like protein MerR-DNA-bind PF09278.11 AAAP01001426.1_1 - 0.79 10.3 10.2 3.1 8.4 4.8 2.5 1 1 1 2 2 2 0 MerR, DNA binding DUF772 PF05598.11 AAAP01001426.1_2 - 1.9e-08 34.2 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Transposase domain (DUF772) Aminotran_5 PF00266.19 AAAP01001428.1_1 - 1.1e-19 70.6 0.0 1.4e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V ABC_tran PF00005.27 AAAP01001429.1_1 - 2.7e-12 47.4 0.0 5.8e-12 46.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AAAP01001429.1_1 - 1.1e-05 25.0 0.5 5.5e-05 22.7 0.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAAP01001429.1_1 - 0.0019 18.0 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 AAAP01001429.1_1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF1416 PF07210.12 AAAP01001429.1_2 - 0.086 12.7 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) LigT_PEase PF02834.16 AAAP01001430.1_1 - 9.7e-23 80.2 0.4 1.2e-11 44.6 0.4 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AAAP01001430.1_1 - 3.8e-15 56.1 0.1 4.7e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 AAAP01001430.1_1 - 0.003 17.5 0.0 0.0035 17.3 0.0 1.3 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain CarD_CdnL_TRCF PF02559.16 AAAP01001432.1_1 - 1.9e-24 86.2 0.0 3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 CarD-like/TRCF domain DUF3357 PF11837.8 AAAP01001433.1_1 - 0.0097 16.4 0.1 0.0098 16.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DinI PF06183.13 AAAP01001434.1_1 - 0.14 12.5 0.0 0.5 10.7 0.0 1.8 1 1 1 2 2 2 0 DinI-like family DUF2336 PF10098.9 AAAP01001435.1_1 - 3.3e-32 112.0 14.1 5e-32 111.4 14.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) HisKA PF00512.25 AAAP01001436.1_1 - 7.2e-09 35.6 0.2 1.4e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAAP01001436.1_1 - 2.2e-06 28.2 0.0 3.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAAP01001436.1_1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain SPOB_a PF14689.6 AAAP01001436.1_1 - 0.011 15.4 0.2 0.029 14.1 0.2 1.7 1 1 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain IMS PF00817.20 AAAP01001438.1_1 - 7.9e-46 155.8 0.0 9.3e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family CbiJ PF02571.14 AAAP01001438.1_2 - 1.7e-08 34.3 0.2 1.8e-08 34.2 0.2 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK PELOTA_1 PF15608.6 AAAP01001438.1_2 - 0.081 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 PELOTA RNA binding domain ILVD_EDD PF00920.21 AAAP01001439.1_1 - 1e-58 199.2 0.0 1.2e-58 199.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Sel1 PF08238.12 AAAP01001439.1_2 - 1.3e-12 48.0 2.4 1.3e-05 25.7 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat HemY_N PF07219.13 AAAP01001439.1_2 - 0.0045 17.2 0.2 0.0075 16.5 0.2 1.3 1 0 0 1 1 1 1 HemY protein N-terminus TPR_6 PF13174.6 AAAP01001439.1_2 - 0.13 12.9 0.6 1.3e+02 3.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 AAAP01001440.1_1 - 2.4e-09 37.2 0.0 7e-06 25.9 0.1 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 AAAP01001440.1_1 - 8.9e-08 32.2 0.0 2.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 AAAP01001440.1_1 - 5.1e-06 25.9 0.7 0.0062 15.8 0.1 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 AAAP01001440.1_1 - 7.4e-06 26.0 0.0 2.5e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 TAP-like protein DLH PF01738.18 AAAP01001440.1_1 - 0.00015 21.4 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAAP01001440.1_1 - 0.00031 20.3 0.1 0.013 14.9 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 AAAP01001440.1_1 - 0.014 15.1 0.0 0.089 12.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) AAA_3 PF07726.11 AAAP01001441.1_1 - 1.7e-60 202.6 0.0 2.3e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01001441.1_1 - 1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01001441.1_1 - 5.4e-06 26.9 0.0 1.7e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 AAAP01001441.1_1 - 4.6e-05 22.6 0.0 6.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAAP01001441.1_1 - 0.00012 21.8 0.0 0.00092 19.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 AAAP01001441.1_1 - 0.00039 20.6 0.0 0.0027 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AAAP01001441.1_1 - 0.017 14.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAAP01001441.1_1 - 0.061 13.1 0.2 0.72 9.6 0.1 2.3 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 AAAP01001441.1_1 - 0.077 13.2 0.5 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAAP01001441.1_1 - 0.09 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AidB_N PF18158.1 AAAP01001442.1_1 - 2.3e-08 34.1 0.1 2.8e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain DUF1525 PF07511.11 AAAP01001443.1_1 - 0.047 13.8 0.1 0.056 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) YcgL PF05166.13 AAAP01001443.1_1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 YcgL domain Septin PF00735.18 AAAP01001443.1_1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Septin DUF423 PF04241.15 AAAP01001443.1_2 - 5.9e-12 45.6 8.6 1e-11 44.9 8.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2157 PF09925.9 AAAP01001443.1_2 - 0.83 9.4 12.5 1.4 8.7 12.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) SCFA_trans PF02667.14 AAAP01001443.1_3 - 3.1e-29 102.3 6.5 4.1e-29 101.9 6.5 1.0 1 0 0 1 1 1 1 Short chain fatty acid transporter DcuC PF03606.15 AAAP01001443.1_3 - 1.8e-05 23.4 2.8 2.3e-05 23.1 2.8 1.1 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier ROK PF00480.20 AAAP01001444.1_1 - 1.6e-10 41.0 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 AAAP01001444.1_1 - 1.3e-05 25.0 2.9 1.3e-05 25.0 2.9 2.4 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 AAAP01001444.1_1 - 0.00053 19.7 3.1 0.00062 19.5 1.2 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_27 PF13463.6 AAAP01001444.1_1 - 0.00083 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain DprA_WH PF17782.1 AAAP01001444.1_1 - 0.0034 17.5 1.5 0.0034 17.5 1.5 2.4 3 0 0 3 3 3 1 DprA winged helix domain HTH_20 PF12840.7 AAAP01001444.1_1 - 0.0089 16.1 3.2 0.029 14.4 0.3 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01001444.1_1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 AAAP01001444.1_1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAAP01001444.1_1 - 0.016 15.4 1.0 0.036 14.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 AAAP01001444.1_1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_15 PF12324.8 AAAP01001444.1_1 - 2.2 8.3 7.3 0.56 10.2 1.5 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Acyltransferase PF01553.21 AAAP01001444.1_2 - 0.0079 15.8 0.0 0.0092 15.6 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase DUF839 PF05787.13 AAAP01001445.1_1 - 2.9e-60 204.9 0.0 3.1e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) RNB PF00773.19 AAAP01001446.1_1 - 5.3e-54 183.7 0.0 5.9e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 RNB domain DUF2125 PF09898.9 AAAP01001447.1_2 - 1.6e-14 54.3 2.1 2.1e-14 53.9 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2125) PAS_9 PF13426.7 AAAP01001448.1_1 - 1.2e-11 44.7 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01001448.1_1 - 4e-06 27.1 0.1 9.6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AAAP01001448.1_1 - 9e-06 26.2 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01001448.1_1 - 0.00012 22.0 0.0 0.00082 19.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAAP01001448.1_1 - 0.00016 21.6 0.2 0.0004 20.4 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01001448.1_1 - 0.003 17.8 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold SPOB_a PF14689.6 AAAP01001448.1_1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain HATPase_c_3 PF13589.6 AAAP01001448.1_1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OMP_b-brl PF13505.6 AAAP01001449.1_1 - 1.3e-10 41.7 1.7 2.1e-10 41.0 1.7 1.4 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OprB PF04966.12 AAAP01001449.1_1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Opacity PF02462.15 AAAP01001449.1_1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Opacity family porin protein DUF4712 PF15830.5 AAAP01001450.1_2 - 0.049 13.3 0.1 0.053 13.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Mqo PF06039.15 AAAP01001451.1_1 - 1.1e-19 70.4 0.0 1.3e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) HTH_17 PF12728.7 AAAP01001452.1_1 - 1.2e-05 25.3 0.1 3e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain Exc PF07825.11 AAAP01001452.1_1 - 0.0073 16.3 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Excisionase-like protein Peptidase_M41 PF01434.18 AAAP01001452.1_3 - 1.8e-19 70.3 0.0 2.3e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M41 Phage_antitermQ PF06530.12 AAAP01001452.1_3 - 0.045 13.7 0.1 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Phage antitermination protein Q PHP PF02811.19 AAAP01001453.1_1 - 2.1e-37 129.0 0.0 2.6e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 PHP domain EAL PF00563.20 AAAP01001454.1_1 - 4.2e-28 98.5 0.0 4.9e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 EAL domain EAL PF00563.20 AAAP01001454.1_2 - 5.5e-23 81.7 0.0 6.2e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 EAL domain Response_reg PF00072.24 AAAP01001455.1_1 - 1.4e-08 34.9 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain OKR_DC_1_N PF03709.15 AAAP01001455.1_1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Peptidase_M20 PF01546.28 AAAP01001456.1_1 - 5.6e-23 81.7 0.0 7.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Aminotran_3 PF00202.21 AAAP01001456.1_1 - 0.18 10.4 0.6 0.31 9.6 0.1 1.6 2 0 0 2 2 2 0 Aminotransferase class-III ADH_N PF08240.12 AAAP01001457.1_2 - 8.7e-05 22.4 0.0 0.00058 19.7 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAAP01001457.1_2 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fer4_NifH PF00142.18 AAAP01001457.1_3 - 2.8e-08 33.5 0.0 3.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.23 AAAP01001457.1_3 - 0.0036 17.4 0.3 0.005 16.9 0.3 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01001457.1_3 - 0.0065 16.4 0.1 0.0083 16.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 AAAP01001457.1_3 - 0.0068 15.9 0.3 0.0085 15.6 0.3 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase NB-ARC PF00931.22 AAAP01001457.1_3 - 0.044 13.0 0.1 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 AAAP01001457.1_3 - 0.045 13.5 0.3 0.051 13.3 0.3 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01001457.1_3 - 0.071 13.4 0.2 0.092 13.0 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01001457.1_3 - 0.076 13.4 0.0 0.076 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ArsA_ATPase PF02374.15 AAAP01001457.1_3 - 0.12 11.5 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_25 PF13481.6 AAAP01001457.1_3 - 0.19 11.3 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01001457.1_3 - 0.2 12.2 0.1 0.24 11.9 0.1 1.1 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 AAAP01001457.1_3 - 0.23 11.1 0.1 0.55 9.8 0.1 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ILVD_EDD PF00920.21 AAAP01001458.1_1 - 8.5e-38 130.2 0.1 9.4e-38 130.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Aldolase PF01081.19 AAAP01001458.1_2 - 5e-27 94.6 2.7 5.5e-27 94.5 2.7 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase PhageMin_Tail PF10145.9 AAAP01001458.1_2 - 0.12 12.2 2.4 0.14 12.0 2.4 1.0 1 0 0 1 1 1 0 Phage-related minor tail protein Oxidored_nitro PF00148.19 AAAP01001459.1_2 - 4.6e-13 48.7 0.0 6.3e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF5540 PF17694.1 AAAP01001459.1_2 - 0.056 13.9 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5540) NMT1_3 PF16868.5 AAAP01001460.1_1 - 7.9e-11 41.9 0.1 1e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 NMT1-like family LPG_synthase_TM PF03706.13 AAAP01001460.1_1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.5 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Pro_dh PF01619.18 AAAP01001460.1_1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Proline dehydrogenase MannoseP_isomer PF01050.18 AAAP01001461.1_1 - 1.5e-31 109.4 0.0 1.7e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.11 AAAP01001461.1_1 - 2e-06 27.4 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAAP01001461.1_1 - 0.089 12.5 0.0 0.098 12.4 0.0 1.0 1 0 0 1 1 1 0 Cupin GerE PF00196.19 AAAP01001461.1_2 - 1.1e-11 44.1 0.3 1.6e-11 43.5 0.3 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAAP01001461.1_2 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HTH_23 PF13384.6 AAAP01001461.1_2 - 0.00078 19.2 1.8 0.0012 18.6 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AAAP01001461.1_2 - 0.0052 16.4 0.3 0.011 15.3 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 QueC PF06508.13 AAAP01001462.1_1 - 2.7e-09 36.8 0.0 3.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Cupin_2 PF07883.11 AAAP01001463.1_1 - 6.8e-20 70.6 0.0 1.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAAP01001463.1_1 - 1.4e-09 38.0 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 AAAP01001463.1_1 - 3.3e-09 36.5 0.0 1.1e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.12 AAAP01001463.1_1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 AAAP01001463.1_1 - 0.00015 21.5 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_7 PF12973.7 AAAP01001463.1_1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain ARD PF03079.14 AAAP01001463.1_1 - 0.0051 17.0 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 AAAP01001463.1_1 - 0.0086 15.8 0.0 0.016 14.9 0.0 1.3 1 1 0 1 1 1 1 Cupin DMSP_lyase PF16867.5 AAAP01001463.1_1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Phenol_MetA_deg PF13557.6 AAAP01001463.1_2 - 0.02 14.9 0.1 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative MetA-pathway of phenol degradation LPAM_2 PF13627.6 AAAP01001463.1_2 - 0.089 12.7 0.7 0.18 11.7 0.7 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF16 PF01519.16 AAAP01001464.1_1 - 0.022 15.2 0.5 0.028 14.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 MqsA_antitoxin PF15731.5 AAAP01001464.1_2 - 3.7e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF1870 PF08965.10 AAAP01001464.1_2 - 0.0062 16.6 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1870) Lar_restr_allev PF14354.6 AAAP01001464.1_2 - 0.019 15.4 0.2 0.043 14.2 0.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar RPEL PF02755.15 AAAP01001464.1_2 - 0.022 14.5 0.1 0.054 13.2 0.1 1.7 1 0 0 1 1 1 0 RPEL repeat zf-RRN7 PF11781.8 AAAP01001464.1_2 - 0.027 14.1 2.2 0.11 12.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nudix_N_2 PF14803.6 AAAP01001464.1_2 - 0.084 12.8 0.3 0.084 12.8 0.3 2.8 4 0 0 4 4 4 0 Nudix N-terminal HTH_31 PF13560.6 AAAP01001464.1_2 - 0.15 12.4 2.6 0.18 12.2 0.3 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain Lyase_aromatic PF00221.19 AAAP01001465.1_1 - 9.8e-80 268.5 0.1 1.3e-79 268.1 0.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase PRODH PF18327.1 AAAP01001465.1_1 - 0.022 15.0 1.3 0.055 13.7 0.3 2.3 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain Urocanase_N PF17391.2 AAAP01001465.1_2 - 2.1e-60 202.0 0.0 2.7e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Urocanase N-terminal domain Urocanase PF01175.18 AAAP01001465.1_2 - 8.8e-19 68.0 7.0 1.2e-18 67.6 7.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain ABM PF03992.16 AAAP01001466.1_2 - 5.9e-15 55.2 0.3 7.2e-15 54.9 0.3 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SOR PF07682.11 AAAP01001466.1_2 - 0.00019 20.4 0.2 0.054 12.4 0.0 2.1 1 1 1 2 2 2 2 Sulphur oxygenase reductase GST_N PF02798.20 AAAP01001466.1_3 - 5.1e-08 33.1 0.0 5.3e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01001466.1_3 - 0.00028 21.1 0.0 0.00029 21.1 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAAP01001466.1_3 - 0.0022 18.4 0.0 0.0022 18.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GATase PF00117.28 AAAP01001467.1_1 - 4.6e-39 134.2 0.0 5.9e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01001467.1_1 - 8.4e-10 38.8 0.2 5.3e-09 36.2 0.1 2.2 1 1 1 2 2 2 1 Peptidase C26 NAD_synthase PF02540.17 AAAP01001467.1_1 - 2.6e-07 30.0 0.1 4.3e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AAAP01001467.1_1 - 1.4e-05 24.1 0.1 2e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 AAAP01001467.1_1 - 0.0097 15.5 0.2 0.023 14.3 0.1 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 AAAP01001467.1_1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 AAAP01001467.1_1 - 0.12 12.1 0.1 0.3 10.7 0.1 1.6 2 0 0 2 2 2 0 Asparagine synthase QueC PF06508.13 AAAP01001467.1_1 - 0.2 11.2 0.0 0.51 9.8 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Adenylsucc_synt PF00709.21 AAAP01001468.1_1 - 8.7e-94 314.8 0.0 9.7e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase GGDEF PF00990.21 AAAP01001469.1_1 - 3.8e-46 156.8 0.0 5e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAAP01001469.1_1 - 0.0032 17.7 0.1 0.0063 16.8 0.1 1.5 1 0 0 1 1 1 1 GGDEF-like domain ABC_tran PF00005.27 AAAP01001470.1_1 - 3.2e-13 50.4 0.0 4.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01001470.1_1 - 2.9e-06 26.9 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AAAP01001470.1_1 - 0.0035 16.2 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class TrkA_N PF02254.18 AAAP01001470.1_1 - 0.027 14.7 0.2 0.6 10.4 0.2 2.2 1 1 0 1 1 1 0 TrkA-N domain Phage_int_SAM_1 PF02899.17 AAAP01001470.1_1 - 0.07 13.4 0.2 3.5 8.0 0.1 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain U71 PF17474.2 AAAP01001470.1_1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Tegument protein UL11 homolog SbcCD_C PF13558.6 AAAP01001470.1_1 - 0.21 11.8 1.2 2.4 8.4 1.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit UPF0051 PF01458.17 AAAP01001472.1_1 - 2.3e-49 168.1 0.0 2.6e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) NAD_Gly3P_dh_N PF01210.23 AAAP01001473.1_1 - 4.5e-44 150.2 0.2 6.1e-44 149.8 0.2 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AAAP01001473.1_1 - 1.6e-07 31.8 0.3 3.7e-07 30.6 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAAP01001473.1_1 - 1.4e-06 28.0 0.1 1.8e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AAAP01001473.1_1 - 2.9e-05 24.3 0.2 4.5e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_C PF07479.14 AAAP01001473.1_1 - 0.00057 20.2 0.1 0.0019 18.5 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 3HCDH_N PF02737.18 AAAP01001473.1_1 - 0.00082 19.3 1.0 0.0012 18.7 1.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAAP01001473.1_1 - 0.0072 16.6 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain DAO PF01266.24 AAAP01001473.1_1 - 0.017 14.8 3.1 0.018 14.6 2.3 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase PDH PF02153.17 AAAP01001473.1_1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.3 1 1 0 1 1 1 0 Prephenate dehydrogenase PALP PF00291.25 AAAP01001473.1_1 - 0.027 13.9 7.4 0.18 11.2 0.9 2.4 1 1 1 3 3 3 0 Pyridoxal-phosphate dependent enzyme NAD_binding_8 PF13450.6 AAAP01001473.1_1 - 0.05 13.8 0.7 0.11 12.7 0.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01001473.1_1 - 0.057 12.6 0.2 0.087 12.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01001473.1_1 - 0.064 12.3 2.7 0.092 11.8 2.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAAP01001473.1_1 - 0.08 12.2 1.1 0.098 11.9 1.1 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_11 PF14833.6 AAAP01001474.1_1 - 1.2e-19 70.7 0.1 1.7e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 AAAP01001474.1_1 - 2.2e-06 27.9 0.0 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gly-zipper_YMGG PF13441.6 AAAP01001475.1_2 - 0.00048 19.8 9.1 0.0025 17.5 3.7 2.1 2 0 0 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAAP01001475.1_2 - 0.0047 16.9 10.9 0.11 12.5 5.8 2.2 2 0 0 2 2 2 2 Glycine zipper DUF3169 PF11368.8 AAAP01001475.1_2 - 0.0075 15.8 0.6 0.48 9.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) SPC12 PF06645.13 AAAP01001475.1_2 - 0.044 13.9 0.4 11 6.2 0.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FtsX PF02687.21 AAAP01001475.1_2 - 0.065 13.7 3.5 0.25 11.8 0.5 2.0 2 0 0 2 2 2 0 FtsX-like permease family DUF1043 PF06295.12 AAAP01001475.1_2 - 0.13 12.2 0.8 2.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3552 PF12072.8 AAAP01001475.1_2 - 0.25 10.7 0.3 4.9 6.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) YtxH PF12732.7 AAAP01001475.1_2 - 0.74 10.4 8.6 0.55 10.8 1.0 2.2 2 0 0 2 2 2 0 YtxH-like protein ATPase_gene1 PF09527.10 AAAP01001475.1_2 - 1.6 9.0 10.3 3.5 7.9 3.0 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Bacteriocin_IIc PF10439.9 AAAP01001475.1_2 - 5.3 7.2 11.1 2.6 8.2 3.8 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.6 AAAP01001475.1_2 - 8.8 6.2 13.7 1.2 8.9 7.2 2.0 2 0 0 2 2 2 0 Glycine-zipper domain ATP-synt_DE_N PF02823.16 AAAP01001475.1_3 - 2.4e-27 94.6 0.1 3.3e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain tRNA_NucTran2_2 PF13735.6 AAAP01001475.1_4 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Alpha-E PF04168.12 AAAP01001476.1_1 - 3.9e-31 108.9 0.0 4.1e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Bact_transglu_N PF08379.10 AAAP01001476.1_2 - 1.5e-21 77.1 0.1 2.4e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAAP01001476.1_2 - 0.0073 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YkuD PF03734.14 AAAP01001477.1_1 - 6.9e-10 39.5 0.2 2.4e-09 37.7 0.2 1.8 1 1 0 1 1 1 1 L,D-transpeptidase catalytic domain Aminotran_1_2 PF00155.21 AAAP01001478.1_1 - 3.3e-34 118.6 0.0 4.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AntA PF08346.12 AAAP01001478.1_1 - 0.097 13.2 0.2 0.2 12.2 0.2 1.4 1 0 0 1 1 1 0 AntA/AntB antirepressor Glyco_hydro_77 PF02446.17 AAAP01001481.1_1 - 2.4e-91 306.9 0.0 3.1e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase CPT PF07931.12 AAAP01001481.1_1 - 0.044 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein VWA_2 PF13519.6 AAAP01001482.1_1 - 3.8e-06 27.5 0.0 8.5e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 AAAP01001482.1_1 - 0.00056 20.2 0.0 0.00078 19.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CbiG_N PF11760.8 AAAP01001482.1_1 - 0.77 9.8 4.1 0.86 9.7 0.1 2.4 2 1 0 2 2 2 0 Cobalamin synthesis G N-terminal VWA PF00092.28 AAAP01001482.1_2 - 4.1e-11 43.4 0.0 5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 AAAP01001482.1_2 - 0.065 13.2 0.0 0.2 11.6 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain ADH_zinc_N_2 PF13602.6 AAAP01001483.1_1 - 3.8e-20 73.3 1.0 6.3e-20 72.6 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAAP01001483.1_1 - 5.5e-17 62.0 0.8 9.1e-17 61.3 0.7 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01001483.1_1 - 0.034 13.4 1.3 0.054 12.8 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 AAAP01001483.1_1 - 0.092 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HTH_1 PF00126.27 AAAP01001484.1_1 - 1.4e-17 63.3 2.0 2.3e-17 62.7 2.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAAP01001484.1_1 - 1.2e-14 54.2 2.0 1.2e-14 54.2 2.0 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_20 PF12840.7 AAAP01001484.1_1 - 0.0014 18.7 0.3 0.0034 17.4 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01001484.1_1 - 0.0048 17.0 0.2 0.0086 16.2 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAAP01001484.1_1 - 0.015 15.1 0.3 0.72 9.7 0.0 2.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAAP01001484.1_1 - 0.023 14.6 0.5 0.058 13.3 0.2 1.9 1 1 0 1 1 1 0 MarR family HTH_23 PF13384.6 AAAP01001484.1_1 - 0.023 14.5 0.1 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_5 PF01022.20 AAAP01001484.1_1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family P22_Cro PF14549.6 AAAP01001484.1_1 - 0.12 12.2 1.2 0.25 11.2 0.6 1.8 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro G6PD_C PF02781.16 AAAP01001485.1_2 - 1.3e-68 231.4 0.0 1.4e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain MHYT PF03707.16 AAAP01001486.1_1 - 1.1e-40 137.6 30.3 4.6e-17 61.9 9.0 3.5 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat PAS_3 PF08447.12 AAAP01001486.1_1 - 3.9e-15 55.9 0.3 7.5e-15 55.0 0.3 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01001486.1_1 - 1.3e-10 41.5 4.1 1.4e-10 41.3 1.7 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAAP01001486.1_1 - 2.7e-07 30.6 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01001486.1_1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.6 1 1 0 1 1 1 1 PAS domain HisKA PF00512.25 AAAP01001486.1_1 - 0.00075 19.5 0.9 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE PF03924.13 AAAP01001486.1_1 - 0.081 12.9 2.0 0.088 12.7 0.3 2.0 2 1 0 2 2 2 0 CHASE domain GFA PF04828.14 AAAP01001487.1_2 - 6.5e-21 74.5 0.5 8.2e-21 74.1 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Amidohydro_1 PF01979.20 AAAP01001488.1_2 - 3.9e-43 148.1 0.1 4.6e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01001488.1_2 - 9.8e-15 55.0 0.7 1.3e-14 54.6 0.7 1.3 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.22 AAAP01001488.1_2 - 0.039 13.3 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Adenosine/AMP deaminase MCH PF02289.16 AAAP01001490.1_1 - 5.6e-111 370.8 0.6 6.3e-111 370.6 0.6 1.0 1 0 0 1 1 1 1 Cyclohydrolase (MCH) P5CR_dimer PF14748.6 AAAP01001491.1_1 - 0.088 13.1 1.7 0.098 12.9 1.7 1.0 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF4135 PF13575.6 AAAP01001491.1_1 - 0.18 11.1 0.0 0.19 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Amidase PF01425.21 AAAP01001492.1_1 - 7.5e-78 262.5 4.1 9.7e-78 262.1 4.1 1.1 1 0 0 1 1 1 1 Amidase PEP_hydrolase PF09370.10 AAAP01001492.1_1 - 0.009 15.3 0.1 1.6 7.8 0.0 2.2 1 1 1 2 2 2 2 Phosphoenolpyruvate hydrolase-like MerR_1 PF13411.6 AAAP01001493.1_1 - 1.1e-12 47.8 0.0 1.2e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01001493.1_1 - 3.6e-09 36.2 0.7 5.2e-09 35.7 0.7 1.2 1 0 0 1 1 1 1 MerR family regulatory protein HTH_Tnp_1 PF01527.20 AAAP01001493.1_1 - 9.8e-08 32.2 0.1 3.3e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAAP01001493.1_1 - 0.00013 22.0 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01001493.1_1 - 0.0013 18.1 0.7 0.0025 17.2 0.0 1.8 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 AAAP01001493.1_1 - 0.0024 18.0 0.1 0.0028 17.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01001493.1_1 - 0.005 16.6 0.1 0.01 15.6 0.1 1.6 1 1 1 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 AAAP01001493.1_1 - 0.0064 16.1 0.0 0.072 12.7 0.0 2.1 1 1 1 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 AAAP01001493.1_1 - 0.018 15.1 0.9 0.03 14.3 0.9 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.6 AAAP01001493.1_1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 AAAP01001493.1_1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 RWP-RK domain Aminotran_1_2 PF00155.21 AAAP01001494.1_1 - 1.8e-26 93.2 0.0 2.1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAAP01001494.1_1 - 0.0001 21.3 0.0 0.00016 20.6 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Flavin_Reduct PF01613.18 AAAP01001495.1_1 - 7e-15 55.4 0.0 8.7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain FAD_binding_2 PF00890.24 AAAP01001496.1_2 - 1.2e-21 77.3 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_28 PF03033.20 AAAP01001496.1_2 - 0.089 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF1684 PF07920.11 AAAP01001497.1_1 - 8.7e-35 120.0 0.1 1e-34 119.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1684) SBP_bac_10 PF07596.11 AAAP01001497.1_1 - 0.091 12.7 0.0 0.091 12.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1559) GLF PF03275.13 AAAP01001498.1_1 - 1.4e-82 276.4 3.6 1.9e-82 276.0 3.6 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 AAAP01001498.1_1 - 3.2e-15 56.1 0.1 6.4e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01001498.1_1 - 7.4e-07 29.1 0.0 5.4e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAAP01001498.1_1 - 2.8e-06 27.0 0.0 0.0016 17.9 0.0 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAAP01001498.1_1 - 0.0001 22.8 0.1 0.00035 21.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01001498.1_1 - 0.00011 22.2 0.0 0.00029 20.9 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAAP01001498.1_1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01001498.1_1 - 0.004 16.3 0.1 0.0065 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAAP01001498.1_1 - 0.0064 15.2 0.0 0.021 13.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 AAAP01001498.1_1 - 0.0071 15.6 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 AAAP01001498.1_1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.19 AAAP01001498.1_1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.12 AAAP01001498.1_1 - 0.025 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GDI PF00996.18 AAAP01001498.1_1 - 0.03 12.8 0.0 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.17 AAAP01001498.1_1 - 0.058 12.6 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 AAAP01001498.1_1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 AAAP01001498.1_1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AAAP01001498.1_1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAAP01001498.1_1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Transpeptidase PF00905.22 AAAP01001499.1_1 - 3.4e-11 42.9 0.0 1.5e-10 40.8 0.0 2.0 2 1 0 2 2 2 1 Penicillin binding protein transpeptidase domain HTH_3 PF01381.22 AAAP01001500.1_1 - 4.4e-13 49.1 0.0 5.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01001500.1_1 - 6.2e-10 38.9 0.0 7e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAAP01001500.1_1 - 9.8e-10 38.6 0.2 2.4e-09 37.4 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01001500.1_1 - 0.0052 16.7 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AAAP01001500.1_1 - 0.042 13.9 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_26 PF13443.6 AAAP01001500.1_1 - 0.05 14.0 0.1 0.053 14.0 0.1 1.1 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain BetR PF08667.10 AAAP01001500.1_1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.2 1 1 0 1 1 1 0 BetR domain Peptidase_S24 PF00717.23 AAAP01001500.1_2 - 4.3e-06 26.6 0.2 6e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like SWIM PF04434.17 AAAP01001501.1_1 - 7.6e-06 25.5 0.4 1.5e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger BPD_transp_1 PF00528.22 AAAP01001502.1_2 - 4.6e-21 75.4 15.3 4.6e-21 75.4 15.3 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PAS_4 PF08448.10 AAAP01001503.1_1 - 1.7e-07 31.5 0.1 2.3e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01001503.1_1 - 3.1e-06 27.1 0.7 2.3e-05 24.3 0.0 2.5 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain DnaB_bind PF10410.9 AAAP01001504.1_1 - 0.19 12.0 0.3 0.19 12.0 0.3 2.5 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Sigma70_r1_1 PF03979.14 AAAP01001504.1_2 - 3.3e-22 78.3 0.2 3.3e-22 78.3 0.2 1.5 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 MarR_2 PF12802.7 AAAP01001504.1_2 - 0.033 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family ACR_tran PF00873.19 AAAP01001505.1_1 - 1.9e-72 244.4 0.0 2.3e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Acetyltransf_1 PF00583.25 AAAP01001506.1_1 - 1.9e-06 28.1 0.0 3.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAAP01001506.1_1 - 4e-05 23.5 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01001506.1_1 - 0.00045 20.3 0.0 0.00087 19.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 AAAP01001506.1_1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TF_Zn_Ribbon PF08271.12 AAAP01001507.1_1 - 0.00021 20.7 0.1 0.00052 19.5 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-TFIIB PF13453.6 AAAP01001507.1_1 - 0.0028 16.9 0.8 0.049 13.0 0.0 2.3 2 0 0 2 2 2 1 Transcription factor zinc-finger Lar_restr_allev PF14354.6 AAAP01001507.1_1 - 0.03 14.7 0.4 0.064 13.6 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_S27e PF01667.17 AAAP01001507.1_1 - 0.043 13.5 1.1 0.091 12.5 1.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 CpXC PF14353.6 AAAP01001507.1_1 - 0.071 13.2 1.4 5.9 7.0 0.1 2.3 1 1 1 2 2 2 0 CpXC protein PPS_PS PF02006.16 AAAP01001507.1_1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Nudix_N_2 PF14803.6 AAAP01001507.1_1 - 0.13 12.2 0.4 0.31 11.0 0.4 1.6 1 1 0 1 1 1 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 AAAP01001507.1_1 - 0.14 12.1 3.0 0.46 10.4 3.0 1.9 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 AAAP01001507.1_1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Mss51 PF13824.6 AAAP01001507.1_1 - 0.18 11.9 1.6 0.34 11.0 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ACC PF17848.1 AAAP01001507.1_1 - 0.29 11.2 4.1 3.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 AAAP01001507.1_1 - 0.32 10.5 2.4 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAAP01001507.1_1 - 1.2 9.3 5.5 12 6.1 0.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain MM_CoA_mutase PF01642.22 AAAP01001509.1_1 - 2.1e-40 138.7 0.0 2.3e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase PhnI PF05861.12 AAAP01001509.1_1 - 0.0096 14.8 0.0 0.01 14.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) Arginosuc_synth PF00764.19 AAAP01001510.1_1 - 1.3e-52 179.5 0.0 1.4e-52 179.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AAAP01001510.1_1 - 0.0009 19.0 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AAAP01001510.1_1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AAAP01001510.1_1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD synthase ATP_bind_3 PF01171.20 AAAP01001510.1_1 - 0.14 11.9 0.1 1.8 8.3 0.0 2.0 1 1 1 2 2 2 0 PP-loop family DSBA PF01323.20 AAAP01001510.1_2 - 1.6e-11 44.3 0.0 1.9e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain TAT_signal PF10518.9 AAAP01001511.1_1 - 0.0096 15.7 0.4 0.021 14.7 0.4 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Arabinose_bd PF12625.7 AAAP01001512.1_2 - 1.2e-36 126.5 1.1 1.2e-36 126.5 1.1 1.9 2 0 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AAAP01001512.1_2 - 1.6e-15 57.1 1.4 1.4e-14 54.1 2.8 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01001512.1_2 - 5.6e-08 32.7 0.2 4.6e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family PriCT_1 PF08708.11 AAAP01001512.1_2 - 0.081 12.7 0.5 0.66 9.8 0.2 2.5 2 1 0 2 2 2 0 Primase C terminal 1 (PriCT-1) HTH_5 PF01022.20 AAAP01001512.1_2 - 0.17 11.7 1.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family PQQ PF01011.21 AAAP01001513.1_1 - 1.4e-09 37.4 6.0 0.16 12.0 0.1 5.4 5 0 0 5 5 5 4 PQQ enzyme repeat PQQ_2 PF13360.6 AAAP01001513.1_1 - 3.7e-09 36.5 14.2 4.8e-09 36.1 8.4 2.6 1 1 1 2 2 2 2 PQQ-like domain Sigma70_r2 PF04542.14 AAAP01001514.1_1 - 1.6e-14 53.4 0.1 2.6e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 NepR PF18557.1 AAAP01001514.1_1 - 9e-06 25.2 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Anti-sigma factor NepR GATase_4 PF13230.6 AAAP01001514.1_2 - 1.4e-51 175.0 0.0 1.6e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Hist_deacetyl PF00850.19 AAAP01001515.1_1 - 1.4e-45 156.2 0.0 2.2e-45 155.5 0.0 1.3 1 1 0 1 1 1 1 Histone deacetylase domain DUF937 PF06078.11 AAAP01001516.1_1 - 7.4e-09 36.3 10.5 4.9e-07 30.4 6.7 2.6 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF937) HTH_AsnC-type PF13404.6 AAAP01001516.1_1 - 0.035 14.0 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Acyl-CoA_dh_M PF02770.19 AAAP01001517.1_1 - 1.5e-06 28.3 0.0 1.8e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Polysacc_synt PF01943.17 AAAP01001518.1_1 - 1.5e-08 34.4 5.9 7e-08 32.2 5.9 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 AAAP01001518.1_1 - 0.006 15.8 1.3 0.25 10.5 0.1 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein UvrD-helicase PF00580.21 AAAP01001519.1_1 - 5.3e-27 95.2 0.0 6.4e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAAP01001519.1_1 - 1.2e-09 38.7 0.0 1.8e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Oxidored_nitro PF00148.19 AAAP01001520.1_1 - 2.5e-27 95.6 0.0 2.8e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase YCII PF03795.14 AAAP01001521.1_3 - 1.4e-15 57.5 0.0 1.5e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF2070 PF09843.9 AAAP01001523.1_1 - 0.43 8.8 5.1 0.53 8.5 5.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4231 PF14015.6 AAAP01001524.1_1 - 1.5 9.3 2.9 4.5 7.8 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) tRNA_edit PF04073.15 AAAP01001525.1_1 - 3.8e-21 75.4 0.0 2.1e-20 73.0 0.0 2.2 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 AAAP01001525.1_1 - 5.8e-13 49.2 0.0 5.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAAP01001525.1_1 - 0.0057 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Bac_DNA_binding PF00216.21 AAAP01001526.1_1 - 7e-18 64.6 0.0 8.4e-18 64.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01001526.1_1 - 4.4e-07 30.0 0.1 4.7e-07 29.9 0.1 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AAAP01001526.1_1 - 0.0029 17.5 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AAAP01001526.1_1 - 0.05 13.7 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 ACP_syn_III_C PF08541.10 AAAP01001526.1_2 - 1e-37 128.2 0.0 1.3e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 AAAP01001526.1_2 - 0.037 14.0 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF1294 PF06961.13 AAAP01001526.1_2 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Sacchrp_dh_C PF16653.5 AAAP01001527.1_1 - 8.4e-20 72.0 0.0 1e-19 71.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 AAAP01001527.1_1 - 1.6e-12 47.9 0.0 5e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glu_synthase PF01645.17 AAAP01001528.1_1 - 1.2e-142 475.4 0.2 1.5e-142 475.1 0.2 1.0 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 AAAP01001528.1_1 - 1.2e-05 24.5 0.7 1.7e-05 24.0 0.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAAP01001528.1_1 - 0.14 11.2 2.8 0.22 10.5 2.8 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain HisKA_3 PF07730.13 AAAP01001529.1_1 - 6.5e-12 45.8 0.3 6.5e-12 45.8 0.3 2.4 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AAAP01001529.1_1 - 2.1e-05 25.0 0.0 0.00014 22.3 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01001529.1_1 - 0.011 15.7 0.2 0.038 14.0 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Harakiri PF15196.6 AAAP01001529.1_1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.1 2 1 0 3 3 3 0 Activator of apoptosis harakiri Response_reg PF00072.24 AAAP01001529.1_2 - 1.4e-20 73.5 0.0 3e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Response regulator receiver domain TadZ_N PF16968.5 AAAP01001529.1_2 - 0.00092 18.9 1.6 0.00092 18.9 1.6 1.5 2 0 0 2 2 2 1 Pilus assembly protein TadZ N-terminal Peptidase_M50 PF02163.22 AAAP01001530.1_1 - 6.8e-29 100.9 0.3 9.6e-29 100.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M50 DUF3267 PF11667.8 AAAP01001530.1_1 - 0.2 12.0 2.7 0.91 9.8 0.0 2.3 2 0 0 2 2 2 0 Putative zincin peptidase DUF3592 PF12158.8 AAAP01001530.1_1 - 0.2 11.7 0.1 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DXPR_C PF13288.6 AAAP01001530.1_2 - 6.3e-35 119.9 0.0 7.6e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain TT_ORF1 PF02956.14 AAAP01001531.1_1 - 2 7.0 5.7 2.7 6.6 5.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 Aldose_epim PF01263.20 AAAP01001532.1_1 - 0.03 13.7 0.0 0.03 13.6 0.0 1.0 1 0 0 1 1 1 0 Aldose 1-epimerase ABC_tran PF00005.27 AAAP01001532.1_2 - 1.1e-14 55.1 0.0 1.6e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 AAAP01001532.1_2 - 0.0077 16.5 2.0 0.1 12.8 2.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AAAP01001532.1_2 - 0.011 15.2 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AAAP01001532.1_2 - 0.18 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class LacI PF00356.21 AAAP01001533.1_1 - 6.3e-19 67.5 0.1 1.7e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 AAAP01001533.1_1 - 3.2e-15 56.3 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 AAAP01001533.1_1 - 9e-11 42.4 2.7 2.5e-10 40.9 0.6 2.4 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AAAP01001533.1_1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_31 PF13560.6 AAAP01001533.1_1 - 0.00069 19.9 0.3 0.0021 18.4 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 AAAP01001533.1_1 - 0.36 10.7 1.7 2.1 8.2 0.1 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family Peptidase_S15 PF02129.18 AAAP01001534.1_2 - 2e-10 40.7 0.1 9.4e-10 38.5 0.1 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 AAAP01001534.1_2 - 5e-10 39.0 0.2 2.4e-08 33.6 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AAAP01001534.1_2 - 5.8e-07 29.2 0.2 0.0038 16.7 0.1 2.0 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AAAP01001534.1_2 - 0.00018 21.2 0.1 0.00034 20.3 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01001534.1_2 - 0.0004 21.0 0.2 0.0029 18.2 0.3 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 AAAP01001534.1_2 - 0.0039 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 AAAP01001534.1_2 - 0.052 13.3 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family NIR_SIR_ferr PF03460.17 AAAP01001535.1_1 - 2.6e-05 24.0 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF3618 PF12277.8 AAAP01001536.1_2 - 0.099 12.9 3.4 0.13 12.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) HWE_HK PF07536.14 AAAP01001537.1_1 - 3.3e-16 59.7 0.3 5.6e-16 59.0 0.3 1.4 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 AAAP01001537.1_1 - 5.7e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01001537.1_1 - 5.8e-06 26.5 0.1 1.8e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AAAP01001537.1_1 - 0.00027 20.9 0.1 0.00069 19.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HisKA_2 PF07568.12 AAAP01001537.1_1 - 0.005 16.9 0.1 0.009 16.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase ADH_zinc_N PF00107.26 AAAP01001538.1_1 - 2.1e-26 92.4 0.1 3.7e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01001538.1_1 - 2.2e-16 61.1 0.1 3.7e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01001538.1_1 - 0.0022 17.4 0.1 0.0032 16.8 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 AAAP01001538.1_1 - 0.0024 17.3 0.2 0.0033 16.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 AAAP01001538.1_1 - 0.0067 16.3 0.2 0.01 15.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ACP_syn_III_C PF08541.10 AAAP01001538.1_1 - 0.015 15.4 0.7 0.031 14.4 0.1 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PSK_trans_fac PF07704.11 AAAP01001538.1_1 - 0.12 13.1 0.0 0.34 11.7 0.0 1.7 1 0 0 1 1 1 0 Rv0623-like transcription factor Bac_DnaA_C PF08299.11 AAAP01001539.1_1 - 5.7e-11 42.3 0.0 7.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix DNA_pol3_beta_2 PF02767.16 AAAP01001539.1_2 - 9.9e-39 132.2 0.0 9.7e-31 106.4 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AAAP01001539.1_2 - 2.2e-35 121.4 0.0 1.9e-31 108.7 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 AAAP01001539.1_2 - 3.6e-14 52.6 0.1 9.4e-12 44.8 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase III beta subunit, C-terminal domain dUTPase PF00692.19 AAAP01001540.1_1 - 9e-09 35.1 0.0 1e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF3710 PF12502.8 AAAP01001540.1_2 - 3.4e-65 219.0 0.9 4.2e-65 218.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) CagA PF03507.13 AAAP01001540.1_2 - 0.037 14.0 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 CagA exotoxin DUF2778 PF10908.8 AAAP01001541.1_1 - 6.8e-26 90.9 0.0 7.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2778) YkuD PF03734.14 AAAP01001541.1_1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 L,D-transpeptidase catalytic domain UreE_N PF02814.15 AAAP01001541.1_2 - 6.4e-12 44.9 2.6 8.7e-12 44.5 1.4 1.8 2 0 0 2 2 2 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.12 AAAP01001541.1_2 - 0.0015 19.0 0.0 0.0015 19.0 0.0 1.9 2 1 1 3 3 3 1 UreE urease accessory protein, C-terminal domain Corona_6B_7B PF03262.13 AAAP01001541.1_3 - 0.13 11.7 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Coronavirus 6B/7B protein Methyltransf_12 PF08242.12 AAAP01001542.1_1 - 2.8e-08 34.4 0.0 4.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01001542.1_1 - 4e-07 30.0 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01001542.1_1 - 8.2e-06 26.4 0.0 1.5e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01001542.1_1 - 0.00038 21.1 0.0 0.00078 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01001542.1_1 - 0.0025 17.6 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01001542.1_1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AA_permease_2 PF13520.6 AAAP01001543.1_1 - 4.4e-31 108.2 6.8 4.8e-31 108.0 6.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01001543.1_1 - 1e-16 60.6 8.0 1.2e-16 60.4 8.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2627 PF11118.8 AAAP01001543.1_1 - 3.4 8.3 5.9 26 5.5 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) IMPa_N_2 PF18650.1 AAAP01001544.1_1 - 0.011 15.1 0.0 0.011 15.0 0.0 1.0 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain GGDEF PF00990.21 AAAP01001545.1_1 - 1.1e-27 96.8 0.0 1.4e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAAP01001545.1_1 - 0.00045 20.4 0.3 0.00056 20.2 0.3 1.1 1 0 0 1 1 1 1 GGDEF-like domain CbiA PF01656.23 AAAP01001546.1_1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 AAAP01001546.1_1 - 0.089 12.2 0.0 0.089 12.2 0.0 1.0 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 AAAP01001546.1_2 - 1.8e-54 184.4 0.0 2.2e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01001546.1_2 - 1.1e-16 61.1 0.2 1.3e-16 60.8 0.2 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAAP01001546.1_2 - 5.3e-11 42.3 0.2 1.7e-09 37.4 0.2 2.0 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 AAAP01001546.1_2 - 7.4e-11 42.0 0.0 9.4e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 AAAP01001546.1_2 - 7.8e-11 41.9 1.2 3.9e-09 36.3 0.5 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AAAP01001546.1_2 - 2.1e-07 30.4 0.4 1e-06 28.2 0.3 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AAAP01001546.1_2 - 3.2e-06 26.8 0.1 3.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 AAAP01001546.1_2 - 0.0023 17.3 0.2 0.0042 16.4 0.2 1.4 1 0 0 1 1 1 1 VirC1 protein ATP_bind_1 PF03029.17 AAAP01001546.1_2 - 0.0035 17.2 0.0 0.14 11.9 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 AAAP01001546.1_2 - 0.024 14.4 0.2 0.054 13.3 0.0 1.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 AAAP01001546.1_2 - 0.035 13.8 0.7 0.057 13.0 0.7 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AAAP01001546.1_2 - 0.055 13.0 0.9 0.12 11.9 0.7 1.6 1 1 0 1 1 1 0 AAA domain LpxK PF02606.14 AAAP01001546.1_2 - 0.057 12.5 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase FTHFS PF01268.19 AAAP01001546.1_2 - 0.058 11.6 0.5 0.075 11.2 0.5 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DnaB_C PF03796.15 AAAP01001546.1_2 - 0.067 12.5 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain GidB PF02527.15 AAAP01001546.1_3 - 7.1e-19 67.8 0.0 7.9e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G CHAT PF12770.7 AAAP01001547.1_1 - 5.3e-05 22.8 0.0 6.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 CHAT domain PP-binding PF00550.25 AAAP01001549.1_1 - 1.1e-09 38.4 0.3 2e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site FecCD PF01032.18 AAAP01001550.1_1 - 6.6e-65 219.2 27.4 7.4e-65 219.0 27.4 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AAAP01001550.1_1 - 6.1e-07 29.2 14.2 7.7e-07 28.9 14.2 1.1 1 0 0 1 1 1 1 ABC 3 transport family HisKA PF00512.25 AAAP01001551.1_1 - 1.6e-11 44.0 1.0 9e-11 41.7 0.7 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAAP01001551.1_1 - 5.3e-06 26.9 0.0 2.3e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 AAAP01001551.1_1 - 0.053 14.0 2.7 0.053 14.0 2.7 2.6 2 1 1 3 3 3 0 Histidine kinase Rrf2 PF02082.20 AAAP01001552.1_1 - 2.3e-11 43.9 0.0 2.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator HTH_6 PF01418.17 AAAP01001552.1_1 - 5.3e-05 23.1 0.0 6.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_AraC PF00165.23 AAAP01001552.1_1 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 AAAP01001552.1_1 - 0.003 17.7 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01001552.1_1 - 0.0049 16.6 0.1 0.011 15.5 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 AAAP01001552.1_1 - 0.0068 16.2 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 HTH DNA binding domain MarR PF01047.22 AAAP01001552.1_1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 AAAP01001552.1_1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 MarR family HTH_27 PF13463.6 AAAP01001552.1_1 - 0.045 14.2 0.0 0.058 13.9 0.0 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.19 AAAP01001552.1_1 - 0.085 12.8 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_1 PF01527.20 AAAP01001552.1_1 - 0.13 12.5 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Transposase Phage-MuB_C PF09077.11 AAAP01001552.1_1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Mu B transposition protein, C terminal NAD_binding_1 PF00175.21 AAAP01001552.1_2 - 9.9e-14 51.9 0.0 1.8e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 AAAP01001552.1_2 - 9.2e-06 26.2 0.0 1.8e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 AAAP01001552.1_2 - 0.00068 19.8 0.0 0.017 15.2 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 AAAP01001552.1_2 - 0.012 15.6 0.2 0.043 13.7 0.1 2.0 2 1 0 2 2 2 0 Protoglobin Flg_bbr_C PF06429.13 AAAP01001553.1_1 - 0.00021 21.4 0.2 0.00072 19.6 0.0 2.0 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal DUF3027 PF11228.8 AAAP01001554.1_1 - 7.3e-47 159.9 0.0 1.2e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) Herpes_BLLF1 PF05109.13 AAAP01001554.1_1 - 9.4 4.1 12.1 12 3.8 12.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF2200 PF09966.9 AAAP01001555.1_2 - 9.8e-35 119.1 0.0 1.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) HxlR PF01638.17 AAAP01001557.1_2 - 2.9e-27 94.3 0.2 4e-27 93.9 0.2 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 AAAP01001557.1_2 - 0.00071 19.6 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.14 AAAP01001557.1_2 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 AAAP01001557.1_2 - 0.0024 17.8 0.1 0.0044 16.9 0.1 1.4 1 0 0 1 1 1 1 MarR family Replic_Relax PF13814.6 AAAP01001557.1_2 - 0.005 16.9 0.3 0.0077 16.3 0.3 1.3 1 0 0 1 1 1 1 Replication-relaxation HTH_Crp_2 PF13545.6 AAAP01001557.1_2 - 0.023 14.7 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_12 PF08461.10 AAAP01001557.1_2 - 0.028 14.3 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TrmB PF01978.19 AAAP01001557.1_2 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAAP01001557.1_2 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator YqgC PF17430.2 AAAP01001557.1_2 - 0.52 10.4 0.1 0.52 10.4 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized YqgC-like MFS_1 PF07690.16 AAAP01001557.1_3 - 5.7e-31 107.7 31.8 7.8e-31 107.3 31.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01001557.1_3 - 3.1e-06 26.4 16.0 4.8e-06 25.7 16.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 AAAP01001557.1_3 - 0.00019 20.0 8.7 0.00023 19.8 8.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PGM_PMM_I PF02878.16 AAAP01001558.1_1 - 2.4e-39 134.2 0.0 3.2e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I MgtC PF02308.16 AAAP01001558.1_2 - 6e-23 81.5 7.7 8e-23 81.1 7.7 1.2 1 0 0 1 1 1 1 MgtC family DUF3487 PF11990.8 AAAP01001558.1_2 - 0.051 13.5 1.8 4.7 7.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Phage_CP76 PF06892.11 AAAP01001558.1_2 - 0.052 13.1 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) rve PF00665.26 AAAP01001559.1_1 - 7.3e-08 32.6 0.0 9.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01001559.1_2 - 1.1e-15 57.2 0.2 1.3e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AAAP01001559.1_2 - 1e-14 54.7 0.1 1.5e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Lsr2 PF11774.8 AAAP01001559.1_2 - 0.096 12.8 0.3 0.12 12.6 0.3 1.1 1 0 0 1 1 1 0 Lsr2 Acyl-CoA_dh_N PF02771.16 AAAP01001560.1_1 - 2.2e-23 83.1 0.0 2.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01001560.1_1 - 2.8e-09 37.1 0.0 4.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF4648 PF15505.6 AAAP01001560.1_1 - 0.067 14.1 0.1 0.15 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) ABC_tran PF00005.27 AAAP01001560.1_2 - 6.3e-10 39.7 0.0 7.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01001560.1_2 - 8.8e-05 22.5 0.2 0.0001 22.2 0.2 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01001560.1_2 - 0.00038 21.0 0.0 0.00044 20.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01001560.1_2 - 0.00044 20.3 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 AAAP01001560.1_2 - 0.0036 16.5 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain TsaE PF02367.17 AAAP01001560.1_2 - 0.005 16.8 0.0 0.0059 16.6 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 AAAP01001560.1_2 - 0.0068 16.1 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01001560.1_2 - 0.018 15.0 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AAAP01001560.1_2 - 0.021 15.0 0.1 0.13 12.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain SMC_N PF02463.19 AAAP01001560.1_2 - 0.023 14.1 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 AAAP01001560.1_2 - 0.032 13.5 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF3584 PF12128.8 AAAP01001560.1_2 - 0.045 11.3 0.1 0.054 11.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MobB PF03205.14 AAAP01001560.1_2 - 0.075 12.9 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 AAAP01001560.1_2 - 0.076 12.6 0.1 0.089 12.4 0.1 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 AAAP01001560.1_2 - 0.08 13.4 0.1 0.095 13.1 0.1 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAAP01001560.1_2 - 0.092 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 AAAP01001560.1_2 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 AAAP01001560.1_2 - 0.13 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_13 PF13166.6 AAAP01001560.1_2 - 0.15 10.7 0.0 0.15 10.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01001560.1_2 - 0.15 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAAP01001560.1_2 - 0.17 11.7 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 NTPase AAA_15 PF13175.6 AAAP01001560.1_2 - 0.19 11.4 0.0 0.21 11.2 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain DUF817 PF05675.12 AAAP01001561.1_1 - 4.2e-41 141.2 8.8 4.8e-41 141.0 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF817) DUF5633 PF18656.1 AAAP01001561.1_2 - 0.087 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Amino_oxidase PF01593.24 AAAP01001562.1_1 - 0.083 12.2 0.0 0.41 9.9 0.0 1.9 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GHMP_kinases_N PF00288.26 AAAP01001562.1_2 - 0.061 13.6 0.5 0.083 13.1 0.5 1.2 1 0 0 1 1 1 0 GHMP kinases N terminal domain SDF PF00375.18 AAAP01001563.1_1 - 6.4e-27 94.6 4.4 7.7e-27 94.3 4.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CheB_methylest PF01339.17 AAAP01001563.1_1 - 0.097 12.4 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 CheB methylesterase IGPD PF00475.18 AAAP01001564.1_2 - 4.9e-56 189.0 1.4 4.9e-56 189.0 1.4 1.5 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Fae PF08714.11 AAAP01001564.1_2 - 0.081 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) LacI PF00356.21 AAAP01001565.1_1 - 4.3e-13 48.8 0.4 8.5e-13 47.9 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 AAAP01001565.1_1 - 0.00032 20.7 0.1 0.00098 19.1 0.0 1.9 3 0 0 3 3 3 1 Helix-turn-helix HTH_Crp_2 PF13545.6 AAAP01001565.1_1 - 0.00047 20.1 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Peripla_BP_1 PF00532.21 AAAP01001565.1_1 - 0.00058 19.4 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_23 PF13384.6 AAAP01001565.1_1 - 0.00078 19.2 1.4 0.9 9.4 0.2 2.8 3 0 0 3 3 3 2 Homeodomain-like domain HTH_31 PF13560.6 AAAP01001565.1_1 - 0.0022 18.3 0.9 0.0071 16.7 0.2 2.3 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01001565.1_1 - 0.0035 16.9 0.1 0.29 10.7 0.0 3.4 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding HNF-1_N PF04814.13 AAAP01001565.1_1 - 0.034 14.8 0.0 0.048 14.3 0.0 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus HTH_AsnC-type PF13404.6 AAAP01001565.1_1 - 0.057 13.3 0.2 1 9.2 0.1 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 AAAP01001565.1_1 - 0.11 12.1 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.7 AAAP01001565.1_1 - 0.11 12.3 1.1 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 MarR family PCC_BT PF18140.1 AAAP01001566.1_1 - 4.1e-31 107.9 0.0 6.4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_carb_C PF02785.19 AAAP01001566.1_1 - 6.1e-25 87.4 0.0 1.7e-24 86.0 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAAP01001566.1_1 - 9.8e-12 44.5 0.3 9.8e-12 44.5 0.3 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAAP01001566.1_1 - 5.5e-06 26.1 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like DUF2118 PF09891.9 AAAP01001566.1_1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) QRPTase_N PF02749.16 AAAP01001566.1_1 - 0.027 14.5 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Abhydrolase_1 PF00561.20 AAAP01001567.1_1 - 1.3e-16 61.0 0.5 1.8e-16 60.6 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AAAP01001567.1_1 - 0.093 12.4 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 AAAP01001567.1_1 - 0.11 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PIN PF01850.21 AAAP01001568.1_2 - 2.1e-12 47.6 0.0 2.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.6 AAAP01001568.1_2 - 0.0028 17.6 0.1 0.02 14.8 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4411) PIN_3 PF13470.6 AAAP01001568.1_2 - 0.016 16.0 0.4 0.02 15.6 0.4 1.2 1 0 0 1 1 1 0 PIN domain DUF5615 PF18480.1 AAAP01001568.1_2 - 0.022 14.5 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) PhdYeFM_antitox PF02604.19 AAAP01001568.1_3 - 1.4e-11 44.0 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Beta-lactamase PF00144.24 AAAP01001569.1_1 - 3.9e-24 85.5 1.3 4.7e-24 85.2 1.3 1.0 1 0 0 1 1 1 1 Beta-lactamase Phageshock_PspD PF09584.10 AAAP01001569.1_2 - 0.023 14.7 1.2 0.03 14.4 1.2 1.3 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) Phage_holin_2_4 PF16082.5 AAAP01001569.1_2 - 0.49 10.2 2.2 0.63 9.8 2.2 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like 5_3_exonuc_N PF02739.16 AAAP01001570.1_1 - 5e-34 117.5 0.0 7.6e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 AAAP01001570.1_1 - 9.7e-31 106.3 0.0 1.7e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 AAAP01001570.1_1 - 1.2e-06 28.4 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HHH_2 PF12826.7 AAAP01001570.1_1 - 0.009 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAAP01001570.1_1 - 0.024 15.2 0.0 0.07 13.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain CobN-Mg_chel PF02514.16 AAAP01001571.1_1 - 4.3e-150 501.6 0.0 1.9e-149 499.5 0.0 1.7 1 1 0 1 1 1 1 CobN/Magnesium Chelatase Adenylsucc_synt PF00709.21 AAAP01001572.1_2 - 3.7e-34 118.4 0.0 4.2e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Mem_trans PF03547.18 AAAP01001573.1_1 - 8.1e-13 47.5 5.6 1.9e-10 39.7 0.2 2.1 1 1 1 2 2 2 2 Membrane transport protein NrsF PF06532.11 AAAP01001574.1_1 - 5.2e-40 137.4 26.4 6.4e-40 137.1 26.4 1.0 1 0 0 1 1 1 1 Negative regulator of sigma F Romo1 PF10247.9 AAAP01001574.1_1 - 0.011 16.0 0.1 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Sigma70_r4_2 PF08281.12 AAAP01001574.1_2 - 8.7e-12 44.5 0.2 1.1e-11 44.2 0.2 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01001574.1_2 - 4.2e-07 29.4 0.1 5.2e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAAP01001574.1_2 - 0.00013 21.9 0.2 0.00015 21.8 0.2 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AAAP01001574.1_2 - 0.021 14.6 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 AAAP01001574.1_2 - 0.042 14.0 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain KORA PF16509.5 AAAP01001574.1_2 - 0.045 14.0 0.1 0.054 13.8 0.1 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_31 PF13560.6 AAAP01001574.1_2 - 0.057 13.8 0.5 0.087 13.2 0.5 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 AAAP01001574.1_2 - 0.063 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_IclR PF09339.10 AAAP01001574.1_2 - 0.16 11.8 2.3 1.5 8.6 2.7 2.2 1 1 1 2 2 2 0 IclR helix-turn-helix domain UPF0114 PF03350.16 AAAP01001576.1_1 - 7.9e-40 135.7 2.5 7.9e-40 135.7 2.5 1.4 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 DUF3169 PF11368.8 AAAP01001576.1_1 - 0.0042 16.6 0.2 0.0064 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Pox_A14 PF05767.12 AAAP01001576.1_1 - 0.2 11.8 2.1 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 AzlC PF03591.14 AAAP01001576.1_2 - 1.4e-22 80.6 6.1 1.7e-22 80.3 6.1 1.1 1 0 0 1 1 1 1 AzlC protein Transposase_20 PF02371.16 AAAP01001577.1_1 - 3.2e-12 46.6 0.1 6.5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family RsdA_SigD_bd PF16751.5 AAAP01001577.1_2 - 0.014 15.7 0.2 0.022 15.0 0.2 1.3 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Cu-oxidase_2 PF07731.14 AAAP01001578.1_1 - 4.5e-19 68.5 0.0 5.5e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 AAAP01001578.1_1 - 0.0064 16.5 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase RNase_H_2 PF13482.6 AAAP01001579.1_1 - 7.6e-11 42.3 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 RNase_H superfamily RNase_PH PF01138.21 AAAP01001579.1_1 - 0.067 13.7 0.7 0.15 12.6 0.7 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 adh_short PF00106.25 AAAP01001581.1_1 - 3.8e-49 166.8 1.2 5.4e-49 166.3 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01001581.1_1 - 1.1e-37 129.9 3.5 1.3e-37 129.6 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01001581.1_1 - 7.5e-19 68.3 2.8 1.1e-18 67.7 1.0 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 AAAP01001581.1_1 - 0.00045 19.8 2.7 0.017 14.6 2.7 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 AAAP01001581.1_1 - 0.013 15.6 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AAAP01001581.1_1 - 0.019 14.6 1.2 0.047 13.3 0.6 2.0 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.10 AAAP01001581.1_1 - 0.049 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RNA_pol_L PF01193.24 AAAP01001581.1_1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain P5CR_dimer PF14748.6 AAAP01001581.1_1 - 0.36 11.1 3.2 0.48 10.7 0.8 2.2 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation E1-E2_ATPase PF00122.20 AAAP01001582.1_1 - 1.4e-44 151.8 4.2 2.6e-44 150.9 4.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01001582.1_1 - 8.9e-21 75.1 0.1 2e-20 74.0 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF554 PF04474.12 AAAP01001584.1_1 - 0.025 14.0 1.3 0.029 13.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Gram_pos_anchor PF00746.21 AAAP01001584.1_1 - 8.8 6.4 7.7 1.1 9.3 0.4 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif MitoNEET_N PF10660.9 AAAP01001584.1_1 - 9.4 6.3 9.2 1.5 8.9 0.9 2.0 1 1 1 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Proton_antipo_M PF00361.20 AAAP01001584.1_2 - 2.7e-27 95.7 6.9 3.4e-27 95.4 6.9 1.1 1 0 0 1 1 1 1 Proton-conducting membrane transporter DUF4131 PF13567.6 AAAP01001584.1_2 - 0.48 10.1 4.4 0.39 10.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 AAAP01001584.1_2 - 7.7 6.6 19.4 2.4 8.2 6.8 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Wzy_C PF04932.15 AAAP01001584.1_2 - 8.5 6.0 11.1 0.4 10.3 3.7 2.1 1 1 1 2 2 2 0 O-Antigen ligase DNA_pol3_beta_3 PF02768.15 AAAP01001585.1_1 - 1.7e-27 95.6 0.0 2.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III beta subunit, C-terminal domain DNA_pol3_beta_2 PF02767.16 AAAP01001585.1_1 - 3.5e-22 78.8 0.0 8.5e-22 77.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III beta subunit, central domain ACR_tran PF00873.19 AAAP01001586.1_1 - 1.2e-59 202.1 0.0 1.4e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family HHH_5 PF14520.6 AAAP01001586.1_1 - 0.00059 20.4 0.1 0.0037 17.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain COX14 PF14880.6 AAAP01001586.1_1 - 0.76 9.7 4.1 3.2 7.7 0.4 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3623 PF12291.8 AAAP01001587.1_1 - 4.5e-63 212.8 7.4 4.9e-63 212.7 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3623) Ldr_toxin PF13940.6 AAAP01001587.1_1 - 0.074 13.1 1.1 0.074 13.1 1.1 2.8 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system DUF5336 PF17270.2 AAAP01001587.1_1 - 0.39 10.3 3.1 0.24 11.0 1.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5336) DUF4131 PF13567.6 AAAP01001587.1_1 - 7.2 6.2 13.1 7.6 6.1 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SCO1-SenC PF02630.14 AAAP01001589.1_1 - 1.5e-19 70.2 0.0 2.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAAP01001589.1_1 - 0.00081 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01001589.1_1 - 0.0065 16.2 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.19 AAAP01001589.1_1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione peroxidase ABC_tran PF00005.27 AAAP01001590.1_1 - 2.9e-31 108.8 0.0 5.2e-31 108.0 0.0 1.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAAP01001590.1_1 - 2.6e-08 34.1 0.0 0.00032 20.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAAP01001590.1_1 - 1.8e-05 24.5 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 AAAP01001590.1_1 - 0.00096 18.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01001590.1_1 - 0.0051 17.3 0.1 0.009 16.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01001590.1_1 - 0.034 13.9 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 AAAP01001590.1_1 - 0.044 14.2 0.0 0.098 13.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAAP01001590.1_1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAAP01001590.1_1 - 0.19 12.0 0.1 1 9.6 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF732 PF05305.14 AAAP01001591.1_1 - 0.2 12.0 1.4 0.24 11.8 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF732) DUF4407 PF14362.6 AAAP01001591.1_2 - 0.00052 19.5 5.1 0.00076 18.9 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) GOLGA2L5 PF15070.6 AAAP01001591.1_2 - 0.057 12.1 0.7 0.071 11.8 0.7 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 HAUS-augmin3 PF14932.6 AAAP01001591.1_2 - 0.079 12.5 1.7 0.1 12.1 1.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FUSC PF04632.12 AAAP01001591.1_2 - 0.085 11.4 13.6 0.1 11.1 13.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1730 PF08331.10 AAAP01001591.1_2 - 0.087 12.7 0.4 0.23 11.4 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1730) Pox_A_type_inc PF04508.12 AAAP01001591.1_2 - 0.15 11.9 1.3 2.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ZapB PF06005.12 AAAP01001591.1_2 - 0.67 10.4 2.5 29 5.2 2.5 2.5 1 1 0 1 1 1 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 AAAP01001591.1_2 - 2 8.7 10.1 0.54 10.6 2.6 2.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain APG6_N PF17675.1 AAAP01001591.1_2 - 6.9 7.2 9.9 7.8 7.0 1.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Rieske PF00355.26 AAAP01001593.1_1 - 8.6e-19 67.3 0.0 1.4e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain GST_N PF02798.20 AAAP01001593.1_2 - 6.1e-05 23.3 0.0 6.3e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAAP01001593.1_2 - 0.00011 22.6 0.0 0.00012 22.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glyco_transf_41 PF13844.6 AAAP01001594.1_1 - 6.7e-23 80.9 0.0 1.1e-19 70.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 41 SBP_bac_6 PF13343.6 AAAP01001594.1_1 - 0.045 13.1 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Ser_hydrolase PF06821.13 AAAP01001595.1_1 - 3.6e-38 131.1 0.0 3.9e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 AAAP01001595.1_1 - 0.00024 21.8 7.0 0.00027 21.6 7.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 AAAP01001595.1_1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 AAAP01001595.1_1 - 0.035 13.4 0.1 0.062 12.6 0.1 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 17kDa_Anti_2 PF16998.5 AAAP01001596.1_1 - 0.0035 17.2 0.0 0.0037 17.2 0.0 1.0 1 0 0 1 1 1 1 17 kDa outer membrane surface antigen Putative_PNPOx PF01243.20 AAAP01001596.1_2 - 1.7e-22 79.4 0.0 2.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 AAAP01001596.1_2 - 3.6e-06 27.5 0.0 4.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UPF0182 PF03699.13 AAAP01001597.1_1 - 2.1e-157 525.5 0.0 2.5e-157 525.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) ABC_membrane PF00664.23 AAAP01001598.1_1 - 0.012 15.3 0.3 0.036 13.7 0.1 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region Cyt_bd_oxida_I PF01654.17 AAAP01001598.1_2 - 2.2e-48 164.9 7.3 2.5e-48 164.7 7.3 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Iso_dh PF00180.20 AAAP01001600.1_1 - 4.1e-37 128.1 0.0 4.7e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DoxX PF07681.12 AAAP01001601.1_1 - 1.4e-08 35.2 14.8 1.4e-08 35.2 14.8 1.6 2 0 0 2 2 2 1 DoxX MFS_1 PF07690.16 AAAP01001602.1_1 - 7.4e-09 35.0 15.9 1e-08 34.5 15.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Response_reg PF00072.24 AAAP01001602.1_2 - 3.6e-22 78.6 0.0 5.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activat PF00158.26 AAAP01001602.1_2 - 3.4e-06 26.9 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01001602.1_2 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain B12-binding PF02310.19 AAAP01001602.1_2 - 0.056 13.5 0.5 0.32 11.0 0.1 2.0 1 1 1 2 2 2 0 B12 binding domain APH PF01636.23 AAAP01001603.1_1 - 7.5e-08 32.6 2.2 1.8e-07 31.3 2.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family ROS_MUCR PF05443.11 AAAP01001604.1_1 - 3.5e-35 120.8 0.0 5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein AMP-binding_C PF13193.6 AAAP01001605.1_1 - 1.3e-10 42.1 0.0 1.5e-10 41.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.12 AAAP01001605.1_2 - 4.8e-13 48.9 0.0 5.7e-12 45.5 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 AAAP01001605.1_2 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Polysacc_synt PF01943.17 AAAP01001606.1_1 - 0.033 13.6 5.6 0.038 13.4 5.6 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Got1 PF04178.12 AAAP01001606.1_1 - 0.042 14.3 3.9 0.056 13.9 3.4 1.6 1 1 0 1 1 1 0 Got1/Sft2-like family Abhydrolase_9_N PF15420.6 AAAP01001606.1_1 - 1.3 9.0 11.5 0.53 10.3 9.0 1.5 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3040 PF11239.8 AAAP01001606.1_1 - 6.3 7.1 12.2 0.87 9.9 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) HD PF01966.22 AAAP01001607.1_1 - 4.8e-14 52.6 0.1 6.5e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01001607.1_1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_6 PF18019.1 AAAP01001607.1_1 - 0.021 15.0 0.5 0.029 14.5 0.5 1.2 1 0 0 1 1 1 0 HD domain Transposase_mut PF00872.18 AAAP01001607.1_2 - 2.9e-21 75.7 0.0 3.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.6 AAAP01001607.1_2 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 DDE domain NAPRTase PF04095.16 AAAP01001608.1_1 - 1.2e-21 77.4 0.0 1.3e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family LamB_YcsF PF03746.16 AAAP01001608.1_2 - 2.5e-94 315.4 0.8 2.8e-94 315.3 0.8 1.0 1 0 0 1 1 1 1 LamB/YcsF family Copper-bind PF00127.20 AAAP01001609.1_1 - 1.9e-19 69.9 0.2 3.1e-19 69.3 0.2 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 AAAP01001609.1_1 - 0.0023 18.0 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain VbhA PF18495.1 AAAP01001610.1_1 - 8.6e-13 47.9 4.4 1.1e-12 47.6 4.1 1.3 1 1 0 1 1 1 1 Antitoxin VbhA DUF1707 PF08044.11 AAAP01001610.1_1 - 0.21 11.7 0.4 0.21 11.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Fic PF02661.18 AAAP01001610.1_2 - 8.4e-14 52.2 0.0 1.6e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family adh_short_C2 PF13561.6 AAAP01001611.1_1 - 1.2e-45 155.9 5.9 1.5e-45 155.6 5.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001611.1_1 - 1.2e-43 148.9 1.4 1.4e-43 148.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01001611.1_1 - 1.5e-12 47.8 3.2 2.1e-12 47.3 3.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01001611.1_1 - 8.4e-07 28.7 0.9 2.1e-06 27.4 0.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01001611.1_1 - 0.0033 16.9 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_transf_4 PF13439.6 AAAP01001611.1_1 - 0.016 15.2 0.1 7.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HEM4 PF02602.15 AAAP01001611.1_1 - 0.018 14.4 1.5 0.072 12.4 1.0 2.3 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD Eno-Rase_NADH_b PF12242.8 AAAP01001611.1_1 - 0.077 12.8 0.4 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ketoacyl-synt_C PF02801.22 AAAP01001611.1_2 - 0.00067 19.7 0.0 0.00096 19.2 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 AAAP01001611.1_2 - 0.0062 17.0 0.0 0.0079 16.6 0.0 1.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Virul_fac_BrkB PF03631.15 AAAP01001612.1_1 - 2.2e-07 30.8 0.3 2.2e-07 30.8 0.3 1.5 2 0 0 2 2 2 1 Virulence factor BrkB DUF2460 PF09343.10 AAAP01001613.1_2 - 5.4e-81 270.9 0.0 6e-81 270.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) DUF2163 PF09931.9 AAAP01001613.1_3 - 4.3e-20 72.6 0.0 4.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2163) LacI PF00356.21 AAAP01001615.1_1 - 1.4e-14 53.6 1.3 2.5e-13 49.6 0.7 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 AAAP01001615.1_1 - 1.5e-07 31.1 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AAAP01001615.1_1 - 0.00087 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain MarR_2 PF12802.7 AAAP01001615.1_1 - 0.033 14.1 1.0 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 MarR family HTH_31 PF13560.6 AAAP01001615.1_1 - 0.046 14.1 2.2 0.088 13.2 0.9 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_N PF00440.23 AAAP01001615.1_1 - 0.18 11.6 0.4 0.41 10.5 0.4 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family F_bP_aldolase PF01116.20 AAAP01001615.1_2 - 5.1e-29 101.6 0.0 5.5e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pyr_redox_2 PF07992.14 AAAP01001616.1_1 - 1.5e-07 31.0 0.1 1.7e-07 30.8 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01001616.1_1 - 0.00067 20.2 0.2 0.00081 19.9 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01001616.1_1 - 0.0057 16.7 0.1 0.0065 16.5 0.1 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 AAAP01001616.1_1 - 0.0079 15.4 0.0 0.009 15.2 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 AAAP01001616.1_1 - 0.027 13.5 0.1 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 AAAP01001616.1_1 - 0.052 13.1 0.3 0.062 12.9 0.3 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01001616.1_1 - 0.075 13.3 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Kelch_1 PF01344.25 AAAP01001616.1_1 - 0.083 12.5 0.2 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 Kelch motif HI0933_like PF03486.14 AAAP01001616.1_1 - 0.09 11.5 0.1 0.09 11.5 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 AAAP01001616.1_1 - 0.12 11.7 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 ThiF family GST_C_3 PF14497.6 AAAP01001616.1_2 - 2.5e-06 27.6 0.0 2.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAAP01001616.1_2 - 0.0037 17.4 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAAP01001616.1_2 - 0.018 15.1 0.0 0.034 14.2 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Leu_Phe_trans PF03588.14 AAAP01001617.1_2 - 0.076 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase DUF4113 PF13438.6 AAAP01001617.1_4 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) AMP-binding PF00501.28 AAAP01001618.1_2 - 9.7e-78 261.6 0.0 1.1e-77 261.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Autotransporter PF03797.19 AAAP01001620.1_1 - 1.5e-31 110.0 4.5 1.8e-31 109.7 4.5 1.1 1 0 0 1 1 1 1 Autotransporter beta-domain PepSY_TM PF03929.16 AAAP01001621.1_1 - 2.5e-71 240.7 11.9 3.1e-71 240.4 11.9 1.0 1 0 0 1 1 1 1 PepSY-associated TM region DUF4405 PF14358.6 AAAP01001621.1_1 - 0.0041 17.6 0.2 0.0041 17.6 0.2 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 AAAP01001621.1_1 - 0.16 11.5 7.7 1.2 8.7 0.6 3.5 3 1 1 4 4 4 0 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 AAAP01001621.1_1 - 0.29 11.3 0.1 0.29 11.3 0.1 2.8 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 DUF1120 PF06551.12 AAAP01001622.1_1 - 0.05 13.8 0.6 0.09 13.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) OmdA PF13376.6 AAAP01001622.1_2 - 1.9 8.6 4.7 0.66 10.0 0.5 2.3 2 1 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated SH3_15 PF18346.1 AAAP01001623.1_1 - 0.022 15.1 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain LPAM_1 PF08139.12 AAAP01001623.1_1 - 5.5 7.7 5.1 9.8 6.9 5.1 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site BPD_transp_2 PF02653.16 AAAP01001624.1_1 - 2.1e-24 86.1 30.2 2.6e-24 85.8 30.2 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Comm PF15957.5 AAAP01001624.1_1 - 0.052 13.9 0.0 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 Commissureless HemY_N PF07219.13 AAAP01001624.1_1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.4 3 0 0 3 3 3 0 HemY protein N-terminus Aminotran_1_2 PF00155.21 AAAP01001625.1_1 - 7e-50 170.2 0.0 8e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01001625.1_1 - 1.4e-05 23.9 0.0 1.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01001625.1_1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAAP01001625.1_1 - 0.0023 16.9 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01001625.1_1 - 0.036 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cadherin-like PF12733.7 AAAP01001627.1_1 - 0.4 11.2 3.9 0.51 10.9 0.2 2.4 1 1 2 3 3 3 0 Cadherin-like beta sandwich domain DUF11 PF01345.18 AAAP01001627.1_1 - 2.3 8.6 14.8 0.71 10.2 1.3 3.1 2 1 0 3 3 3 0 Domain of unknown function DUF11 RHH_4 PF13467.6 AAAP01001628.1_1 - 2.6e-20 72.0 0.5 3.6e-20 71.6 0.5 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix domain Spidroin_MaSp PF11260.8 AAAP01001628.1_2 - 0.045 14.0 0.1 0.051 13.9 0.1 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 DUF1328 PF07043.13 AAAP01001628.1_2 - 1.8 8.8 4.0 23 5.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) MTS PF05175.14 AAAP01001629.1_1 - 2.8e-44 150.6 0.0 3.3e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAAP01001629.1_1 - 2.2e-08 34.7 0.0 5.5e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01001629.1_1 - 5.4e-05 23.9 0.0 0.00013 22.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 AAAP01001629.1_1 - 9.6e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 AAAP01001629.1_1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 AAAP01001629.1_1 - 0.00036 21.1 0.0 0.0011 19.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01001629.1_1 - 0.00055 19.8 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01001629.1_1 - 0.0006 19.6 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAAP01001629.1_1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_4 PF02056.16 AAAP01001629.1_1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase PseudoU_synth_2 PF00849.22 AAAP01001629.1_2 - 1.4e-13 51.2 0.0 2.5e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAAP01001629.1_2 - 1.3e-07 31.2 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain SFTA2 PF15210.6 AAAP01001629.1_2 - 0.08 12.9 0.4 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 Surfactant-associated protein 2 PhageMin_Tail PF10145.9 AAAP01001630.1_1 - 0.0028 17.5 1.6 0.0028 17.5 1.6 2.9 1 1 1 2 2 2 1 Phage-related minor tail protein Mu-like_Pro PF10123.9 AAAP01001630.1_1 - 0.011 15.3 1.0 0.43 10.1 0.1 2.1 1 1 1 2 2 2 0 Mu-like prophage I protein DUF327 PF03885.13 AAAP01001630.1_1 - 0.17 11.8 0.0 0.91 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) TMP_2 PF06791.13 AAAP01001630.1_1 - 4.4 6.9 16.4 2.3 7.8 10.7 2.6 1 1 1 3 3 3 0 Prophage tail length tape measure protein Ribosomal_S4 PF00163.19 AAAP01001631.1_1 - 1.7e-24 86.6 3.3 3e-24 85.8 3.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AAAP01001631.1_1 - 7.4e-19 67.2 0.2 1.3e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AAAP01001631.1_1 - 0.00014 21.6 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 S4 domain GH-E PF14410.6 AAAP01001631.1_1 - 0.098 13.1 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Hydrolase_3 PF08282.12 AAAP01001632.1_1 - 9.2e-35 120.6 0.0 1.1e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAAP01001632.1_1 - 2.6e-07 30.5 0.0 0.00032 20.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AAAP01001632.1_1 - 2.5e-05 24.7 0.1 0.00016 22.0 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01001632.1_1 - 0.004 17.2 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01001632.1_1 - 0.14 12.5 6.2 6.1 7.2 0.2 3.6 2 2 2 4 4 4 0 haloacid dehalogenase-like hydrolase Bac_DNA_binding PF00216.21 AAAP01001633.1_1 - 7.7e-17 61.3 0.2 8.9e-17 61.1 0.2 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein LapA_dom PF06305.11 AAAP01001633.1_2 - 9.9e-08 31.7 0.4 5.1e-07 29.4 0.0 2.0 1 1 1 2 2 2 1 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 AAAP01001633.1_2 - 0.008 16.2 1.0 0.012 15.7 1.0 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III EMC3_TMCO1 PF01956.16 AAAP01001633.1_2 - 0.14 11.9 0.0 18 5.0 0.6 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PRAI PF00697.22 AAAP01001633.1_3 - 5.5e-11 42.6 0.0 6e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF11 PF01345.18 AAAP01001634.1_1 - 1.8 8.9 9.3 1.7 9.0 7.4 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF11 Glyco_hydro_38 PF18438.1 AAAP01001635.1_1 - 0.096 12.7 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 RF3_C PF16658.5 AAAP01001635.1_2 - 1.8e-41 141.0 0.0 2.2e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 AAAP01001635.1_2 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II GATase_4 PF13230.6 AAAP01001636.1_1 - 1.4e-51 175.0 0.0 1.6e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 AAAP01001636.1_1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMN_red PF03358.15 AAAP01001637.1_1 - 3.2e-22 78.9 1.1 3.4e-22 78.9 0.1 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AAAP01001637.1_1 - 1.9e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 AAAP01001637.1_1 - 0.0055 17.0 0.0 0.0082 16.4 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin domain RNase_J_C PF17770.1 AAAP01001638.1_1 - 2.9e-15 57.1 0.0 4.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain RMMBL PF07521.12 AAAP01001638.1_1 - 8.6e-08 32.0 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain SecA_DEAD PF07517.14 AAAP01001639.1_1 - 8.5e-12 45.0 0.1 1.2e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain Biotin_lipoyl_2 PF13533.6 AAAP01001639.1_2 - 3e-07 30.1 2.4 2.9e-06 27.0 0.1 3.3 4 0 0 4 4 4 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01001639.1_2 - 0.026 14.4 0.0 0.069 13.0 0.0 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme HlyD_3 PF13437.6 AAAP01001639.1_2 - 0.036 14.8 0.1 12 6.6 0.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein zf-C3HC4_5 PF17121.5 AAAP01001641.1_2 - 0.021 14.7 0.2 0.024 14.5 0.2 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Terminase_6 PF03237.15 AAAP01001642.1_1 - 4.2e-16 59.2 0.0 5.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Terminase-like family BPD_transp_1 PF00528.22 AAAP01001643.1_1 - 1.1e-18 67.7 8.8 1.1e-18 67.7 8.8 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component AMP-binding PF00501.28 AAAP01001644.1_1 - 2.9e-48 164.5 0.1 3.6e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF3305 PF11749.8 AAAP01001645.1_1 - 1e-39 135.9 0.3 1.2e-39 135.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3305) DUF3306 PF11748.8 AAAP01001645.1_2 - 1.4e-24 87.3 0.2 2e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3306) Peptidase_M1 PF01433.20 AAAP01001646.1_1 - 2.2e-52 177.8 0.0 2.7e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 AAAP01001646.1_1 - 4.1e-11 43.4 0.0 6.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 AAAP01001646.1_1 - 2.6e-10 40.6 0.0 4.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M61 PF05299.12 AAAP01001646.1_1 - 0.043 14.2 0.3 0.1 13.0 0.2 1.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF2268 PF10026.9 AAAP01001646.1_1 - 0.051 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF2063 PF09836.9 AAAP01001646.1_1 - 0.11 12.7 0.3 0.86 9.9 0.1 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain TetR_C_28 PF17937.1 AAAP01001647.1_1 - 0.00013 22.3 0.4 0.00022 21.6 0.4 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Choline_sulf_C PF12411.8 AAAP01001647.1_1 - 0.094 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal AMP-binding PF00501.28 AAAP01001648.1_1 - 1.3e-43 149.2 0.0 1.4e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 AAAP01001648.1_2 - 5.2e-19 68.1 0.0 5.6e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Kinase-PPPase PF03618.14 AAAP01001649.1_1 - 2.9e-31 109.2 0.0 3.4e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase URO-D PF01208.17 AAAP01001649.1_2 - 1.8e-33 116.2 0.0 2e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Rz1 PF06085.11 AAAP01001649.1_2 - 0.16 11.8 0.5 0.28 11.0 0.5 1.4 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor AMP-binding PF00501.28 AAAP01001650.1_1 - 1.4e-19 70.0 0.0 1.7e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Metallophos_2 PF12850.7 AAAP01001651.1_1 - 0.00017 21.8 0.6 0.0027 17.9 0.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Vps62 PF06101.11 AAAP01001651.1_1 - 0.18 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 DUF2791 PF10923.8 AAAP01001652.1_1 - 2.1e-60 204.8 0.0 2.3e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) DEAD PF00270.29 AAAP01001652.1_2 - 7.3e-27 94.2 0.0 8.9e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01001652.1_2 - 0.00067 19.7 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AAAP01001652.1_2 - 0.0016 18.2 0.2 0.0085 15.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain PucR PF07905.11 AAAP01001652.1_2 - 0.042 14.1 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family AAA_25 PF13481.6 AAAP01001652.1_2 - 0.066 12.8 0.9 0.11 12.0 0.9 1.5 1 1 0 1 1 1 0 AAA domain Bac_surface_Ag PF01103.23 AAAP01001654.1_1 - 1.6e-11 44.3 0.0 3.5e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Surface antigen FmdA_AmdA PF03069.15 AAAP01001655.1_1 - 6.4e-11 41.7 0.0 2.9e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Acetamidase/Formamidase family TRAM PF01938.20 AAAP01001655.1_1 - 0.073 13.1 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 TRAM domain Peptidase_S24 PF00717.23 AAAP01001656.1_2 - 0.0037 17.2 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like COX2_TM PF02790.15 AAAP01001657.1_2 - 0.012 15.7 1.3 0.019 15.1 1.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF898 PF05987.13 AAAP01001657.1_2 - 0.26 10.3 4.5 0.38 9.8 4.3 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) UCR_Fe-S_N PF10399.9 AAAP01001657.1_3 - 0.037 13.4 0.3 0.14 11.5 0.1 2.2 1 1 1 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_transf_4 PF13439.6 AAAP01001658.1_1 - 4.5e-17 62.6 3.2 4.5e-17 62.6 3.2 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01001658.1_1 - 6.5e-13 49.4 7.8 6.5e-13 49.4 7.8 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 AAAP01001658.1_1 - 8.8e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AAAP01001658.1_1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like HTH_23 PF13384.6 AAAP01001658.1_1 - 0.042 13.6 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 AAAP01001658.1_1 - 0.06 13.4 0.1 0.28 11.3 0.1 2.1 1 0 0 1 1 1 0 Winged helix-turn helix ATP-grasp_5 PF13549.6 AAAP01001659.1_1 - 3.8e-14 52.7 1.3 7e-14 51.8 1.3 1.5 1 0 0 1 1 1 1 ATP-grasp domain Acetyltransf_3 PF13302.7 AAAP01001659.1_1 - 3.4e-13 50.4 0.0 6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01001659.1_1 - 3.1e-08 33.9 0.0 4.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAAP01001659.1_1 - 1.3e-05 25.1 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAAP01001659.1_1 - 0.0036 17.5 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01001659.1_1 - 0.004 17.5 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01001659.1_1 - 0.048 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAAP01001659.1_1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ferritin PF00210.24 AAAP01001659.1_2 - 3.8e-10 39.8 0.6 4.1e-10 39.7 0.6 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rx_N PF18052.1 AAAP01001659.1_2 - 0.03 14.6 0.6 0.042 14.1 0.6 1.2 1 0 0 1 1 1 0 Rx N-terminal domain Peripla_BP_6 PF13458.6 AAAP01001660.1_1 - 0.0039 16.9 0.3 0.0051 16.5 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Lactonase PF10282.9 AAAP01001660.1_2 - 3.7e-15 56.0 0.5 4.6e-05 22.8 0.1 3.5 1 1 1 3 3 3 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AAAP01001660.1_2 - 4.5e-14 51.8 0.9 4.1e-05 22.3 0.0 4.0 1 1 2 4 4 4 4 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 AAAP01001660.1_2 - 5.5e-09 36.2 0.0 0.26 11.6 0.0 5.9 1 1 6 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 AAAP01001660.1_2 - 1.1e-06 28.4 0.6 0.17 11.5 0.2 3.5 1 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Me-amine-dh_H PF06433.11 AAAP01001660.1_2 - 1.2e-05 24.3 0.3 0.33 9.8 0.0 4.1 1 1 2 4 4 4 2 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.12 AAAP01001660.1_2 - 9.3e-05 22.3 0.1 6.1 6.9 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat NHL PF01436.21 AAAP01001660.1_2 - 0.00011 22.1 0.4 40 4.5 0.0 6.4 6 1 1 7 7 7 0 NHL repeat DUF1513 PF07433.11 AAAP01001660.1_2 - 0.0012 18.0 0.6 2.3 7.2 0.1 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF1513) Phytase-like PF13449.6 AAAP01001660.1_2 - 0.0069 16.4 0.3 0.38 10.6 0.3 3.1 1 1 0 1 1 1 1 Esterase-like activity of phytase FlaG PF03646.15 AAAP01001660.1_2 - 0.025 14.7 6.6 12 6.1 0.0 4.8 5 0 0 5 5 5 0 FlaG protein Arylesterase PF01731.20 AAAP01001660.1_2 - 0.08 13.1 0.0 5.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Arylesterase DUF1236 PF06823.12 AAAP01001660.1_2 - 0.084 12.8 1.8 33 4.4 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1236) RskA PF10099.9 AAAP01001661.1_1 - 6.3 7.1 14.2 6.9 6.9 13.3 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Hexapep_2 PF14602.6 AAAP01001661.1_2 - 1.3e-14 53.6 8.4 3.5e-13 49.0 0.5 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AAAP01001661.1_2 - 0.0042 16.8 5.1 2.4 8.0 1.4 3.9 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) THDPS_M PF14789.6 AAAP01001661.1_2 - 0.092 12.9 0.3 0.24 11.5 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase middle HTH_53 PF18606.1 AAAP01001662.1_1 - 0.052 13.2 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain EamA PF00892.20 AAAP01001662.1_2 - 2e-16 60.4 9.6 2.8e-16 59.9 9.6 1.2 1 0 0 1 1 1 1 EamA-like transporter family Apolipoprotein PF01442.18 AAAP01001663.1_1 - 0.0017 18.2 1.7 0.0018 18.2 1.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ZapB PF06005.12 AAAP01001663.1_1 - 0.0028 18.0 3.5 0.0038 17.6 3.2 1.3 1 1 0 1 1 1 1 Cell division protein ZapB TetR_C_31 PF17940.1 AAAP01001663.1_1 - 0.0075 16.5 6.6 0.02 15.1 5.7 1.9 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Rab5-bind PF09311.11 AAAP01001663.1_1 - 0.013 15.0 2.0 0.013 14.9 2.0 1.0 1 0 0 1 1 1 0 Rabaptin-like protein CREPT PF16566.5 AAAP01001663.1_1 - 0.017 15.3 1.1 0.02 15.1 1.1 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour GAS PF13851.6 AAAP01001663.1_1 - 0.025 13.9 2.6 0.032 13.6 2.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 AAAP01001663.1_1 - 0.053 13.6 1.8 0.064 13.4 1.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 AAAP01001663.1_1 - 0.069 12.9 2.3 0.2 11.4 0.5 2.0 1 1 1 2 2 2 0 Septum formation initiator Metal_resist PF13801.6 AAAP01001663.1_1 - 0.62 10.3 10.3 0.71 10.1 10.3 1.1 1 0 0 1 1 1 0 Heavy-metal resistance Esterase_phd PF10503.9 AAAP01001664.1_2 - 4.4e-23 81.9 1.9 4.4e-23 81.9 1.9 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 AAAP01001664.1_2 - 2.2e-05 24.2 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AAAP01001664.1_2 - 0.0085 15.6 0.2 0.011 15.2 0.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tannase PF07519.11 AAAP01001664.1_2 - 0.037 13.0 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_3 PF07859.13 AAAP01001664.1_2 - 0.067 13.0 0.9 0.074 12.9 0.2 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_7 PF12715.7 AAAP01001664.1_2 - 0.29 10.3 0.0 0.4 9.9 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase family PIN PF01850.21 AAAP01001665.1_1 - 1e-08 35.7 0.0 1.2e-08 35.5 0.0 1.0 1 0 0 1 1 1 1 PIN domain EccE PF11203.8 AAAP01001665.1_1 - 0.37 11.1 3.9 0.53 10.6 3.7 1.3 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE PSK_trans_fac PF07704.11 AAAP01001665.1_2 - 1.4e-22 80.2 0.6 1.5e-22 80.1 0.6 1.0 1 0 0 1 1 1 1 Rv0623-like transcription factor RHH_1 PF01402.21 AAAP01001665.1_2 - 0.04 13.9 0.9 0.1 12.6 0.9 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family DEAD PF00270.29 AAAP01001665.1_3 - 4.2e-14 52.7 0.0 5.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01001665.1_3 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AAAP01001665.1_3 - 0.026 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain SecA_DEAD PF07517.14 AAAP01001665.1_3 - 0.093 12.0 0.0 0.11 11.8 0.0 1.2 1 1 0 1 1 1 0 SecA DEAD-like domain GARS_N PF02844.15 AAAP01001665.1_3 - 0.12 13.2 0.0 0.28 12.0 0.0 1.6 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Microtub_bd PF16796.5 AAAP01001665.1_3 - 0.21 11.5 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 Microtubule binding Hydrolase PF00702.26 AAAP01001666.1_1 - 9.3e-09 35.9 0.0 1.3e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAAP01001666.1_1 - 1.4e-08 35.1 0.0 1.6e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01001666.1_1 - 0.00049 20.1 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like SDH_beta PF03315.15 AAAP01001667.1_1 - 2.3e-39 135.2 0.0 3e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Serine dehydratase beta chain Peptidase_M24 PF00557.24 AAAP01001667.1_2 - 4.2e-39 134.4 0.0 4.7e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 LysR_substrate PF03466.20 AAAP01001668.1_1 - 0.012 15.0 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 LysR substrate binding domain DUF4194 PF13835.6 AAAP01001668.1_2 - 4.7e-18 65.5 0.0 5.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) CysA_C_terminal PF17850.1 AAAP01001668.1_3 - 0.031 14.8 0.0 0.038 14.6 0.0 1.1 1 0 0 1 1 1 0 CysA C-terminal regulatory domain MS_channel PF00924.18 AAAP01001669.1_1 - 5e-10 39.3 2.6 5e-10 39.3 2.6 2.3 2 0 0 2 2 2 1 Mechanosensitive ion channel MTABC_N PF16185.5 AAAP01001669.1_1 - 0.13 11.8 1.1 0.29 10.6 0.1 1.8 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF1345 PF07077.11 AAAP01001669.1_1 - 2.6 7.7 14.1 3.5 7.3 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) FA_desaturase PF00487.24 AAAP01001669.1_1 - 5.8 6.7 11.1 0.94 9.3 4.1 2.0 1 1 1 2 2 2 0 Fatty acid desaturase LapA_dom PF06305.11 AAAP01001669.1_1 - 7.2 6.5 12.3 0.27 11.1 0.3 3.3 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain BPD_transp_1 PF00528.22 AAAP01001672.1_1 - 6.1e-18 65.2 14.1 7.1e-18 65.0 14.1 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Pyr_redox_dim PF02852.22 AAAP01001673.1_1 - 9.7e-19 67.7 0.1 1.2e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain ABC_tran PF00005.27 AAAP01001674.1_2 - 4e-32 111.6 0.0 5.2e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01001674.1_2 - 1.6e-07 31.4 0.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01001674.1_2 - 0.00012 21.6 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01001674.1_2 - 0.00026 21.4 1.6 0.00076 19.9 1.6 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01001674.1_2 - 0.0054 16.5 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01001674.1_2 - 0.0061 16.5 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase TOBE PF03459.17 AAAP01001674.1_2 - 0.011 16.1 1.2 0.011 16.1 1.2 2.2 2 0 0 2 2 2 0 TOBE domain SbcCD_C PF13558.6 AAAP01001674.1_2 - 0.011 15.9 0.6 0.35 11.1 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 AAAP01001674.1_2 - 0.044 13.7 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 AAAP01001674.1_2 - 0.053 13.9 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01001674.1_2 - 0.091 13.0 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAAP01001674.1_2 - 0.13 12.4 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TOBE_2 PF08402.10 AAAP01001674.1_2 - 0.98 9.6 6.3 0.67 10.2 1.3 3.1 3 0 0 3 3 3 0 TOBE domain ADP_ribosyl_GH PF03747.14 AAAP01001675.1_2 - 4.1e-12 46.4 0.0 4.8e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Mso1_Sec1_bdg PF14475.6 AAAP01001675.1_2 - 0.059 13.0 0.1 0.059 13.0 0.1 1.5 2 0 0 2 2 2 0 Sec1-binding region of Mso1 CagE_TrbE_VirB PF03135.14 AAAP01001676.1_2 - 9e-11 42.3 0.0 8.3e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system ThrE PF06738.12 AAAP01001677.1_1 - 7.8e-07 28.7 24.3 0.00024 20.5 3.8 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 AAAP01001677.1_1 - 0.00012 22.2 5.6 0.00012 22.2 5.6 1.8 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Bax1-I PF01027.20 AAAP01001677.1_1 - 1.1 9.0 10.5 4 7.2 3.9 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4231 PF14015.6 AAAP01001677.1_1 - 8.2 7.0 8.2 0.26 11.8 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) STAS_2 PF13466.6 AAAP01001678.1_1 - 1.7e-08 34.7 0.1 2.3e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01001678.1_1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 STAS domain Transgly_assoc PF04226.13 AAAP01001678.1_2 - 3.8e-09 36.6 10.6 3.8e-09 36.6 10.6 2.2 2 0 0 2 2 2 1 Transglycosylase associated protein DUF4234 PF14018.6 AAAP01001678.1_2 - 0.0055 16.8 3.0 0.015 15.4 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4234) Phage_holin_8 PF16931.5 AAAP01001678.1_2 - 0.18 11.8 5.8 0.13 12.2 4.0 1.6 1 1 1 2 2 2 0 Putative phage holin ABC2_membrane_3 PF12698.7 AAAP01001678.1_2 - 1.2 8.2 6.7 1.3 8.1 6.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein FeoB_C PF07664.12 AAAP01001678.1_2 - 5.2 6.8 11.2 2.2 8.0 0.2 2.6 2 1 1 3 3 3 0 Ferrous iron transport protein B C terminus Mak_N_cap PF18085.1 AAAP01001678.1_3 - 0.073 14.1 0.8 0.41 11.7 0.4 2.0 2 0 0 2 2 2 0 Maltokinase N-terminal cap domain PGM_PMM_IV PF00408.20 AAAP01001679.1_2 - 0.00038 20.6 0.3 0.00044 20.4 0.3 1.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Beta_helix PF13229.6 AAAP01001679.1_3 - 7.4e-15 55.1 16.3 1.1e-10 41.6 5.9 1.6 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 AAAP01001679.1_3 - 0.00012 21.5 2.7 0.16 11.2 0.9 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 AAAP01001679.1_3 - 0.00088 19.2 2.7 0.0045 16.9 1.9 1.9 1 1 1 2 2 2 2 Pectate lyase superfamily protein ABC_tran PF00005.27 AAAP01001680.1_1 - 2.4e-11 44.3 0.0 2.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01001680.1_1 - 1.3e-06 28.5 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01001680.1_1 - 8.4e-06 26.4 0.1 8.6e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01001680.1_1 - 7.2e-05 22.5 0.1 0.00011 21.9 0.1 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAAP01001680.1_1 - 7.8e-05 22.2 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AAAP01001680.1_1 - 0.00018 21.2 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01001680.1_1 - 0.00054 19.7 0.1 0.00073 19.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01001680.1_1 - 0.001 19.5 0.2 0.0012 19.2 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AAAP01001680.1_1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01001680.1_1 - 0.003 17.8 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01001680.1_1 - 0.0031 17.9 0.0 0.0041 17.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AAAP01001680.1_1 - 0.0061 16.6 0.1 0.0079 16.2 0.1 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 AAAP01001680.1_1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 AAAP01001680.1_1 - 0.012 15.2 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 AAAP01001680.1_1 - 0.014 15.8 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAAP01001680.1_1 - 0.015 15.6 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01001680.1_1 - 0.044 14.3 0.1 0.054 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01001680.1_1 - 0.049 13.6 0.1 0.063 13.2 0.1 1.1 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 AAAP01001680.1_1 - 0.057 12.1 0.0 0.07 11.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01001680.1_1 - 0.075 12.4 0.1 0.095 12.1 0.1 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AAAP01001680.1_1 - 0.075 12.9 0.0 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 AAAP01001680.1_1 - 0.077 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 AAAP01001680.1_1 - 0.086 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAAP01001680.1_1 - 0.086 11.9 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 AAAP01001680.1_1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AAAP01001680.1_1 - 0.21 11.4 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal PRK PF00485.18 AAAP01001680.1_1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 AAAP01001680.1_1 - 0.22 11.0 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3584 PF12128.8 AAAP01001680.1_1 - 0.3 8.5 0.2 0.37 8.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.12 AAAP01001680.1_1 - 0.35 10.1 0.1 0.35 10.1 0.1 1.4 2 0 0 2 2 2 0 Zeta toxin Peripla_BP_6 PF13458.6 AAAP01001680.1_2 - 1.5e-11 44.5 0.0 1.8e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein tRNA-synt_1g PF09334.11 AAAP01001681.1_1 - 6.7e-90 301.7 0.0 1.8e-45 155.4 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAAP01001681.1_1 - 1.5e-26 92.8 0.1 2.6e-12 45.8 0.1 3.5 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AAAP01001681.1_1 - 6.7e-07 28.9 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAAP01001681.1_1 - 7.2e-05 21.9 0.0 0.045 12.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) ACR_tran PF00873.19 AAAP01001682.1_1 - 1e-14 53.3 1.2 1.1e-14 53.1 1.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family AzlC PF03591.14 AAAP01001682.1_1 - 0.00096 19.6 0.7 0.0012 19.3 0.7 1.2 1 0 0 1 1 1 1 AzlC protein DUF4435 PF14491.6 AAAP01001684.1_1 - 1.1e-06 28.8 0.0 1.4e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4435) NolB PF17398.2 AAAP01001685.1_2 - 0.072 13.5 0.0 0.093 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein NolB CofC PF01983.16 AAAP01001686.1_2 - 5.3e-07 29.0 0.2 0.0082 15.3 0.1 2.1 1 1 1 2 2 2 2 Guanylyl transferase CofC like SQS_PSY PF00494.19 AAAP01001687.1_1 - 1.7e-56 191.6 2.5 1.9e-56 191.5 2.5 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 AAAP01001687.1_2 - 9.3e-05 21.9 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Mem_trans PF03547.18 AAAP01001688.1_1 - 0.079 11.3 1.2 0.086 11.2 1.2 1.0 1 0 0 1 1 1 0 Membrane transport protein Maf PF02545.14 AAAP01001688.1_2 - 4.8e-43 146.9 0.0 5.4e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Biotin_carb_N PF00289.22 AAAP01001688.1_3 - 1.1e-17 64.5 0.1 1.4e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Sdh5 PF03937.16 AAAP01001689.1_2 - 3.4e-25 87.8 0.5 4.1e-25 87.5 0.5 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase SBP_bac_8 PF13416.6 AAAP01001691.1_1 - 0.00045 20.1 0.0 0.00065 19.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01001691.1_1 - 0.0034 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LPAM_1 PF08139.12 AAAP01001691.1_1 - 0.86 10.2 3.0 1.9 9.1 3.0 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site tRNA_m1G_MT PF01746.21 AAAP01001692.1_1 - 4.4e-48 163.6 0.0 5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Glycos_transf_2 PF00535.26 AAAP01001693.1_1 - 4.2e-14 52.7 0.0 5.5e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01001693.1_1 - 2.2e-06 27.7 2.0 2.9e-06 27.3 2.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01001693.1_1 - 1.5e-05 25.4 0.1 2.6e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Osmo_MPGsynth PF09488.10 AAAP01001693.1_1 - 0.0024 16.6 0.1 0.0047 15.7 0.2 1.4 1 1 1 2 2 2 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) FG-GAP PF01839.23 AAAP01001693.1_1 - 0.22 11.7 2.3 0.37 11.0 1.0 2.2 2 0 0 2 2 2 0 FG-GAP repeat YkuD PF03734.14 AAAP01001694.1_1 - 3.2e-10 40.6 0.0 3.9e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain BPD_transp_1 PF00528.22 AAAP01001694.1_2 - 1.3e-19 70.6 11.7 1.8e-19 70.2 11.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component PIG-L PF02585.17 AAAP01001695.1_1 - 3.2e-20 73.1 0.0 3.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase QueC PF06508.13 AAAP01001695.1_2 - 4.4e-52 176.6 0.0 5.3e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC PGM_PMM_I PF02878.16 AAAP01001696.1_1 - 3.9e-28 97.9 0.1 4.4e-28 97.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I GDP_Man_Dehyd PF16363.5 AAAP01001696.1_2 - 3.9e-11 42.9 0.0 4.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01001696.1_2 - 0.00049 19.6 0.5 0.00078 19.0 0.5 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABC2_membrane PF01061.24 AAAP01001698.1_1 - 3.1e-09 36.6 2.3 3.1e-09 36.6 2.3 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01001698.1_1 - 0.0018 17.4 4.7 0.002 17.3 4.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Phage_holin_3_2 PF04550.12 AAAP01001698.1_1 - 0.12 12.9 0.8 0.12 12.9 0.8 2.2 2 0 0 2 2 2 0 Phage holin family 2 GATase PF00117.28 AAAP01001698.1_2 - 1.9e-08 34.3 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01001698.1_2 - 2.5e-06 27.4 0.5 4.2e-05 23.4 0.5 2.0 1 1 0 1 1 1 1 Peptidase C26 ATP-synt_C PF00137.21 AAAP01001698.1_2 - 8.3 6.9 8.3 0.94 9.9 3.5 2.0 2 1 0 2 2 2 0 ATP synthase subunit C tRNA-synt_1b PF00579.25 AAAP01001699.1_1 - 1.2e-34 120.0 0.0 1.9e-34 119.3 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) stn_TNFRSF12A PF12191.8 AAAP01001701.1_1 - 0.016 15.4 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain AhpC-TSA PF00578.21 AAAP01001701.1_2 - 1.1e-36 125.5 0.0 1.2e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01001701.1_2 - 5.1e-20 71.7 0.0 5.9e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 AAAP01001701.1_2 - 0.00014 21.4 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 AAAP01001701.1_2 - 0.003 17.6 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme YwhD PF08741.10 AAAP01001701.1_2 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 YwhD family HWE_HK PF07536.14 AAAP01001701.1_3 - 0.36 11.5 3.0 0.67 10.7 1.9 1.9 1 1 1 2 2 2 0 HWE histidine kinase MFS_1 PF07690.16 AAAP01001702.1_1 - 8.5e-13 47.9 32.9 1.2e-12 47.5 32.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 AAAP01001702.1_1 - 5.3e-06 25.1 21.0 7.1e-06 24.7 21.0 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector FGGY_C PF02782.16 AAAP01001703.1_2 - 5.7e-16 58.8 0.3 7.3e-16 58.5 0.3 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Trans_reg_C PF00486.28 AAAP01001704.1_1 - 2.9e-20 72.1 0.1 3.4e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Ribosomal_L18 PF17135.4 AAAP01001704.1_2 - 0.049 13.0 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e GcrA PF07750.11 AAAP01001704.1_3 - 2.3e-51 174.4 0.0 2.8e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 GcrA cell cycle regulator HTH_38 PF13936.6 AAAP01001704.1_3 - 0.093 12.5 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DNA_gyraseB PF00204.25 AAAP01001705.1_1 - 5.8e-43 146.4 0.0 7.8e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 AAAP01001705.1_1 - 2.9e-15 56.3 0.1 6.6e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Toprim domain DUF4880 PF16220.5 AAAP01001705.1_1 - 0.023 14.6 0.3 0.076 12.9 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Hydrolase PF00702.26 AAAP01001706.1_1 - 1.8e-45 155.8 10.9 1.8e-45 155.8 10.9 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 AAAP01001706.1_1 - 1.4e-22 80.1 1.4 2.5e-22 79.3 1.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.7 AAAP01001706.1_1 - 9.4e-08 32.7 1.0 5.9e-07 30.1 1.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01001706.1_1 - 6.1e-06 26.2 0.9 0.00069 19.4 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01001706.1_1 - 0.0011 19.1 0.1 0.0057 16.7 0.0 2.1 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase PCP_red PF08369.10 AAAP01001706.1_1 - 1.8 8.8 4.7 2.8 8.2 2.6 2.5 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit TM_helix PF05552.12 AAAP01001706.1_1 - 6.7 6.8 8.0 19 5.4 1.3 3.4 3 0 0 3 3 3 0 Conserved TM helix CAP PF00188.26 AAAP01001707.1_1 - 1e-12 49.0 0.0 1.3e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4188 PF13826.6 AAAP01001708.1_2 - 1.4e-28 99.6 0.0 1.7e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 AAAP01001708.1_2 - 0.0001 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase HTH_1 PF00126.27 AAAP01001709.1_1 - 7.7e-22 77.0 0.7 8.4e-22 76.9 0.7 1.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAAP01001709.1_1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01001709.1_1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 MarR family GST_N PF02798.20 AAAP01001709.1_2 - 2.4e-18 66.2 0.0 5.2e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAAP01001709.1_2 - 9.1e-17 61.2 0.0 1.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01001709.1_2 - 1.5e-14 54.1 0.0 3.3e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAAP01001709.1_2 - 1e-06 28.9 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAAP01001709.1_2 - 1.9e-05 24.6 2.6 5.6e-05 23.1 2.1 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAAP01001709.1_2 - 0.00042 21.0 0.0 0.0025 18.5 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 AAAP01001709.1_2 - 0.00069 19.8 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 AAAP01001709.1_2 - 0.19 11.9 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin FixH PF05751.11 AAAP01001710.1_1 - 0.00016 21.7 0.0 0.00021 21.3 0.0 1.1 1 0 0 1 1 1 1 FixH YtkA PF13115.6 AAAP01001710.1_1 - 0.00022 21.7 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 YtkA-like Invasin_D3 PF09134.10 AAAP01001710.1_1 - 0.073 13.4 0.0 0.089 13.1 0.0 1.1 1 0 0 1 1 1 0 Invasin, domain 3 DUF1775 PF07987.11 AAAP01001710.1_2 - 6.9e-20 71.8 0.0 5.3e-09 36.5 0.0 2.0 1 1 1 2 2 2 2 Domain of unkown function (DUF1775) DGF-1_5 PF11038.8 AAAP01001711.1_2 - 0.087 12.1 0.6 1.1 8.5 0.0 2.3 2 1 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Big_6 PF17936.1 AAAP01001711.1_2 - 0.096 13.0 3.2 1.5 9.1 0.2 3.0 2 1 0 2 2 2 0 Bacterial Ig domain IF3_C PF00707.22 AAAP01001712.1_1 - 5.1e-32 109.7 0.9 7.3e-32 109.2 0.1 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Big_2 PF02368.18 AAAP01001713.1_1 - 2e-17 62.8 7.4 2e-17 62.8 7.4 2.4 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 2) Big_4 PF07532.11 AAAP01001713.1_1 - 7.9e-15 54.3 0.6 7.9e-15 54.3 0.6 3.7 4 0 0 4 4 4 1 Bacterial Ig-like domain (group 4) AMP-binding PF00501.28 AAAP01001714.1_1 - 5.4e-14 51.6 0.0 7.5e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01001714.1_1 - 1.9e-10 41.5 0.0 8.6e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 AAAP01001714.1_1 - 0.0005 20.4 0.0 0.00091 19.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Amidohydro_1 PF01979.20 AAAP01001715.1_1 - 2.9e-16 59.7 0.1 3.5e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01001715.1_1 - 4e-10 39.8 3.2 7.5e-10 38.9 2.4 1.7 1 1 1 2 2 2 1 Amidohydrolase family Response_reg PF00072.24 AAAP01001716.1_1 - 2.1e-27 95.5 0.1 3.1e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activat PF00158.26 AAAP01001716.1_1 - 1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01001716.1_1 - 1.9e-05 24.8 0.0 5.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain B12-binding PF02310.19 AAAP01001716.1_1 - 0.014 15.4 0.1 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain AAA_25 PF13481.6 AAAP01001716.1_1 - 0.026 14.1 0.5 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain HGD-D PF06050.13 AAAP01001716.1_1 - 0.096 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Ion_trans_2 PF07885.16 AAAP01001717.1_1 - 5.5e-11 42.3 2.2 1.5e-10 40.9 0.2 2.1 2 0 0 2 2 2 1 Ion channel VMA21 PF09446.10 AAAP01001717.1_1 - 0.021 14.9 0.7 0.051 13.7 0.7 1.6 1 0 0 1 1 1 0 VMA21-like domain DUF4131 PF13567.6 AAAP01001717.1_1 - 1.7 8.2 5.9 1.5 8.4 3.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CBS PF00571.28 AAAP01001718.1_2 - 1.7e-20 73.2 2.4 3.9e-11 43.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain SbmA_BacA PF05992.12 AAAP01001719.1_1 - 1.7e-29 103.3 3.2 2e-29 103.1 3.2 1.0 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.15 AAAP01001719.1_1 - 2.5e-26 92.7 2.2 3.2e-26 92.3 2.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_29 PF13555.6 AAAP01001719.1_1 - 4.7e-06 26.2 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAAP01001719.1_1 - 0.00012 22.6 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 AAAP01001719.1_1 - 0.00058 20.4 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01001719.1_1 - 0.0036 17.7 0.2 0.041 14.3 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AAAP01001719.1_1 - 0.0075 15.9 0.2 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01001719.1_1 - 0.008 16.0 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01001719.1_1 - 0.07 13.4 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01001719.1_1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Plug PF07715.15 AAAP01001720.1_1 - 1e-20 74.3 0.1 2.3e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Catalase-rel PF06628.12 AAAP01001721.1_1 - 3.2e-21 75.3 0.0 5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase PF00199.19 AAAP01001721.1_1 - 4.9e-20 72.0 0.7 6.2e-20 71.6 0.7 1.1 1 0 0 1 1 1 1 Catalase Acetyltransf_1 PF00583.25 AAAP01001722.1_3 - 4.5e-13 49.5 0.0 5.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01001722.1_3 - 2.3e-08 34.3 0.0 2.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01001722.1_3 - 3.7e-05 23.7 0.0 4.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01001722.1_3 - 9.6e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAAP01001722.1_3 - 0.045 14.4 0.0 0.051 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01001722.1_3 - 0.051 13.7 0.0 0.12 12.6 0.0 1.6 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase BPD_transp_1 PF00528.22 AAAP01001724.1_2 - 2e-12 47.2 6.5 2e-12 47.2 6.5 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 AAAP01001724.1_2 - 0.051 13.6 0.3 0.051 13.6 0.3 2.9 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) Oxidored_q2 PF00420.24 AAAP01001724.1_2 - 0.16 11.6 6.5 0.086 12.5 2.7 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4293 PF14126.6 AAAP01001724.1_2 - 1.3 9.3 6.3 2 8.6 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DNA_pol3_beta PF00712.19 AAAP01001725.1_1 - 3.4e-28 98.2 0.0 3.8e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 AAAP01001725.1_1 - 0.0048 17.1 0.0 0.0052 17.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III beta subunit, central domain YabP PF07873.11 AAAP01001725.1_1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 YabP family DUF2303 PF10065.9 AAAP01001725.1_2 - 2.1e-12 46.8 0.0 2.2e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2303) OEP PF02321.18 AAAP01001726.1_1 - 1.6e-45 155.3 20.5 1.1e-31 110.1 12.5 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Fusion_gly PF00523.18 AAAP01001726.1_1 - 0.053 11.8 1.7 0.092 11.0 1.7 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 BPD_transp_1 PF00528.22 AAAP01001728.1_2 - 3.3e-19 69.3 16.3 4.1e-19 69.0 16.3 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF4164 PF13747.6 AAAP01001729.1_1 - 0.026 14.8 0.1 0.033 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HlyIII PF03006.20 AAAP01001729.1_2 - 1.2e-17 64.4 11.0 1.4e-17 64.1 11.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DDE_Tnp_IS66 PF03050.14 AAAP01001730.1_2 - 8.8e-23 81.2 0.0 9.5e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family AnmK PF03702.14 AAAP01001731.1_1 - 3.3e-87 292.9 0.3 4e-87 292.7 0.3 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase baeRF_family10 PF18854.1 AAAP01001731.1_1 - 0.016 15.4 0.7 0.016 15.4 0.7 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Sigma54_activat PF00158.26 AAAP01001732.1_1 - 3.7e-11 43.0 0.1 5.2e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01001732.1_1 - 0.0038 17.0 1.5 0.0069 16.1 0.2 2.2 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family Sigma54_activ_2 PF14532.6 AAAP01001732.1_1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain LysE PF01810.18 AAAP01001733.1_1 - 2.7e-28 98.8 14.6 3.3e-28 98.5 14.6 1.1 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAAP01001733.1_1 - 0.0055 16.4 5.2 0.02 14.6 5.1 1.9 1 1 0 1 1 1 1 Integral membrane protein TerC family FAD_binding_4 PF01565.23 AAAP01001734.1_1 - 7.1e-15 55.0 2.8 8.4e-15 54.7 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain zf_Rg PF17915.1 AAAP01001735.1_2 - 0.18 11.2 3.0 0.21 11.0 1.7 1.7 2 0 0 2 2 2 0 Reverse gyrase zinc finger AP_endonuc_2 PF01261.24 AAAP01001736.1_1 - 9.6e-34 116.7 0.4 1.4e-33 116.1 0.4 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyoxalase_4 PF13669.6 AAAP01001736.1_1 - 0.065 13.5 0.2 2 8.7 0.0 2.9 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PhaC_N PF07167.13 AAAP01001737.1_2 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Phasin_2 PF09361.10 AAAP01001737.1_2 - 0.61 10.4 4.9 2.7 8.3 0.7 2.3 2 0 0 2 2 2 0 Phasin protein HTH_18 PF12833.7 AAAP01001739.1_2 - 3.8e-13 49.5 1.7 7.7e-13 48.5 1.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01001739.1_2 - 4.6e-10 39.3 0.0 2.5e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAAP01001739.1_2 - 0.00025 20.7 3.3 0.091 12.6 0.5 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 AAAP01001739.1_2 - 0.035 14.1 1.1 1 9.4 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix HlyD_D23 PF16576.5 AAAP01001741.1_1 - 4.8e-10 39.0 3.6 6.6e-10 38.6 3.6 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01001741.1_1 - 2.2e-07 31.5 3.1 0.00075 20.2 0.2 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01001741.1_1 - 6.6e-06 25.9 13.6 4.5e-05 23.2 2.9 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01001741.1_1 - 4.8e-05 23.1 0.5 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 AAAP01001741.1_1 - 0.0014 18.5 5.8 0.0023 17.8 5.8 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein TPR_MLP1_2 PF07926.12 AAAP01001741.1_1 - 0.38 10.8 6.1 3.8 7.6 0.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein COX2 PF00116.20 AAAP01001742.1_1 - 5.1e-44 149.0 0.1 9.6e-44 148.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 AAAP01001742.1_1 - 6.4e-20 71.1 1.2 9.9e-20 70.5 1.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Bac_rhodopsin PF01036.18 AAAP01001742.1_1 - 0.007 16.0 0.7 0.011 15.3 0.7 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Yip1 PF04893.17 AAAP01001742.1_1 - 0.019 14.7 2.8 0.03 14.0 2.8 1.2 1 0 0 1 1 1 0 Yip1 domain Acyl_transf_3 PF01757.22 AAAP01001742.1_1 - 0.02 14.0 1.1 0.032 13.3 1.1 1.2 1 0 0 1 1 1 0 Acyltransferase family NPCC PF08058.11 AAAP01001742.1_1 - 0.073 13.1 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Nuclear pore complex component Molybdopterin PF00384.22 AAAP01001743.1_1 - 7.4e-28 97.7 0.0 9e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 AAAP01001743.1_1 - 0.012 15.5 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain TPP_enzyme_M PF00205.22 AAAP01001743.1_1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Glyco_tranf_2_3 PF13641.6 AAAP01001744.1_1 - 3.9e-09 36.7 0.1 6.1e-09 36.1 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01001744.1_1 - 3.2e-06 27.2 0.1 4.5e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AAAP01001744.1_1 - 1.4e-05 24.7 0.4 2e-05 24.2 0.4 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 AAAP01001744.1_1 - 1.6e-05 24.7 0.0 0.061 13.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family Glyco_transf_7C PF02709.14 AAAP01001744.1_1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF2076 PF09849.9 AAAP01001745.1_2 - 0.0015 18.6 0.0 0.0018 18.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Acyl-CoA_dh_2 PF08028.11 AAAP01001745.1_3 - 3.8e-09 36.9 3.3 5.5e-09 36.4 3.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAAP01001745.1_3 - 0.047 13.9 1.1 0.079 13.2 1.1 1.3 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain COX4_pro_2 PF07835.12 AAAP01001746.1_1 - 2.1e-12 46.9 0.0 2.1e-12 46.9 0.0 2.9 2 1 1 3 3 3 1 Bacterial aa3 type cytochrome c oxidase subunit IV AlaDh_PNT_C PF01262.21 AAAP01001746.1_3 - 9.7e-17 61.0 6.8 1.1e-16 60.8 6.8 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FTSW_RODA_SPOVE PF01098.19 AAAP01001747.1_1 - 1.3e-55 188.8 4.1 1.7e-55 188.5 4.1 1.0 1 0 0 1 1 1 1 Cell cycle protein Glyco_transf_28 PF03033.20 AAAP01001747.1_2 - 1.1e-32 113.0 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain HisKA PF00512.25 AAAP01001749.1_1 - 6.8e-14 51.7 3.2 7.1e-14 51.6 0.9 2.2 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 AAAP01001749.1_1 - 9.1e-13 48.7 0.1 4.4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 GAF domain DUF4118 PF13493.6 AAAP01001749.1_1 - 2.5e-10 40.1 3.4 5e-10 39.1 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) DUF1275 PF06912.11 AAAP01001750.1_1 - 2.8e-13 50.2 12.3 3.5e-13 49.9 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) OAM_dimer PF16554.5 AAAP01001750.1_1 - 0.1 13.0 0.2 3 8.4 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase ANAPC4_WD40 PF12894.7 AAAP01001750.1_3 - 3e-12 46.7 0.0 1.4e-05 25.3 0.0 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 AAAP01001750.1_3 - 1.6e-08 35.1 0.1 0.012 16.5 0.0 4.1 3 1 1 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.12 AAAP01001750.1_3 - 0.0014 18.5 1.5 0.59 10.1 0.2 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat BiPBP_C PF06832.12 AAAP01001750.1_3 - 0.016 15.2 1.3 0.051 13.6 0.4 2.2 2 1 1 3 3 3 0 Penicillin-Binding Protein C-terminus Family Glyoxalase_6 PF18029.1 AAAP01001751.1_2 - 8.8e-12 45.8 0.7 9.7e-12 45.6 0.7 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain AP_endonuc_2 PF01261.24 AAAP01001751.1_3 - 4.6e-28 98.1 0.8 5.5e-28 97.8 0.8 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CheR PF01739.18 AAAP01001752.1_1 - 1.4e-16 60.6 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 AAAP01001752.1_1 - 0.00021 22.0 0.0 0.00033 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01001752.1_1 - 0.0032 18.1 0.0 0.0049 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01001752.1_1 - 0.0073 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01001752.1_1 - 0.01 16.5 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PknG_TPR PF16918.5 AAAP01001752.1_1 - 0.051 12.3 0.0 0.061 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Methyltransf_31 PF13847.6 AAAP01001752.1_1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Proton_antipo_N PF00662.20 AAAP01001753.1_1 - 9.3e-24 83.3 0.3 9.3e-24 83.3 0.3 2.4 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 AAAP01001753.1_1 - 1e-15 57.7 1.6 1e-15 57.7 1.6 2.7 3 1 0 3 3 3 1 Proton-conducting membrane transporter MFS_1 PF07690.16 AAAP01001753.1_1 - 0.64 8.9 27.2 0.16 10.9 7.1 2.7 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF2517 PF10725.9 AAAP01001753.1_1 - 6.7 6.6 5.9 0.98 9.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) UreF PF01730.16 AAAP01001754.1_1 - 2.7e-09 37.7 4.3 4e-09 37.2 4.3 1.2 1 0 0 1 1 1 1 UreF Urease_gamma PF00547.18 AAAP01001754.1_2 - 1e-15 57.8 0.0 1.1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 AAAP01001754.1_3 - 3.4e-44 148.8 0.0 4.2e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 Urease beta subunit Urease_alpha PF00449.20 AAAP01001754.1_4 - 1e-15 58.2 0.0 1.1e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain MCPsignal PF00015.21 AAAP01001755.1_1 - 7.6e-15 55.1 13.4 7.6e-15 55.1 13.4 2.2 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01001755.1_1 - 0.016 15.5 5.6 6.5 7.1 0.0 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 AAAP01001755.1_1 - 0.04 14.4 1.7 19 5.8 0.1 3.4 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Response_reg PF00072.24 AAAP01001755.1_2 - 0.0019 18.3 0.0 0.002 18.2 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PUCC PF03209.15 AAAP01001755.1_2 - 0.19 10.7 0.0 0.21 10.6 0.0 1.0 1 0 0 1 1 1 0 PUCC protein Mrr_cat PF04471.12 AAAP01001756.1_1 - 5.7e-22 77.9 0.0 1.6e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease Mrr_cat_2 PF13156.6 AAAP01001756.1_1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Hjc PF01870.18 AAAP01001756.1_1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF2034 PF10356.9 AAAP01001756.1_1 - 0.2 11.1 0.0 2.4 7.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2034) Hexapep PF00132.24 AAAP01001757.1_1 - 4.2e-06 26.3 9.3 1.3e-05 24.7 0.7 3.9 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01001757.1_1 - 0.0035 17.1 0.9 0.0035 17.1 0.9 3.3 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase HWE_HK PF07536.14 AAAP01001758.1_1 - 2.3e-20 73.1 0.1 6.9e-20 71.5 0.1 1.9 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 AAAP01001758.1_1 - 5.8e-18 65.0 0.1 1e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01001758.1_1 - 3e-10 40.1 0.0 6.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01001758.1_1 - 1.5e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain HisKA_2 PF07568.12 AAAP01001758.1_1 - 0.0024 17.9 0.1 0.0077 16.3 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase PAS_4 PF08448.10 AAAP01001758.1_1 - 0.0059 16.8 1.4 0.0093 16.2 0.1 1.9 2 1 1 3 3 3 1 PAS fold HATPase_c_2 PF13581.6 AAAP01001758.1_1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CoA_binding_3 PF13727.6 AAAP01001759.1_1 - 1.6e-10 41.3 1.0 3e-10 40.4 1.0 1.4 1 0 0 1 1 1 1 CoA-binding domain Glyco_trans_1_4 PF13692.6 AAAP01001759.1_2 - 0.014 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01001759.1_2 - 0.02 14.4 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 HrcA PF01628.21 AAAP01001761.1_1 - 2.4e-53 181.3 0.0 2.7e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 HrcA protein C terminal domain DUF3618 PF12277.8 AAAP01001761.1_1 - 0.00038 20.6 0.5 0.00089 19.5 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) DNA_pol_lambd_f PF10391.9 AAAP01001761.1_1 - 0.05 13.4 0.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda ACR_tran PF00873.19 AAAP01001761.1_2 - 2.7e-19 68.4 9.9 2.9e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01001761.1_2 - 0.63 8.9 7.7 0.68 8.8 7.7 1.0 1 0 0 1 1 1 0 MMPL family ACR_tran PF00873.19 AAAP01001762.1_2 - 6.7e-75 252.5 6.8 8.8e-75 252.1 6.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01001762.1_2 - 1.4e-05 24.2 18.5 2.1e-05 23.7 18.5 1.3 1 0 0 1 1 1 1 MMPL family SecD_SecF PF02355.16 AAAP01001762.1_2 - 0.84 9.0 11.1 5.1 6.4 11.3 2.1 1 1 0 1 1 1 0 Protein export membrane protein AcrZ PF10766.9 AAAP01001762.1_2 - 9.2 5.9 11.8 0.44 10.1 5.6 2.1 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ TonB_dep_Rec PF00593.24 AAAP01001763.1_1 - 0.037 13.9 0.1 0.042 13.7 0.1 1.1 1 0 0 1 1 1 0 TonB dependent receptor TonB_dep_Rec PF00593.24 AAAP01001763.1_2 - 1.4e-06 28.5 1.7 1.5e-06 28.4 1.7 1.0 1 0 0 1 1 1 1 TonB dependent receptor Methyltransf_4 PF02390.17 AAAP01001764.1_1 - 3.5e-39 134.0 0.0 4.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 AAAP01001764.1_1 - 0.00046 20.8 0.1 0.0037 17.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01001764.1_1 - 0.0008 20.1 0.0 0.0017 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01001764.1_1 - 0.03 15.0 0.0 2.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Toprim_C_rpt PF13368.6 AAAP01001764.1_2 - 2.5e-56 187.5 9.9 3.8e-21 74.8 0.1 4.6 5 0 0 5 5 5 3 Topoisomerase C-terminal repeat zf-C4_Topoisom PF01396.19 AAAP01001764.1_2 - 7.1e-17 60.9 1.4 2.2e-15 56.1 1.2 3.0 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger HC2 PF07382.11 AAAP01001764.1_2 - 0.0029 17.7 27.8 0.0042 17.2 27.8 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Hc1 PF07432.13 AAAP01001764.1_2 - 0.12 12.7 24.2 0.19 12.1 24.2 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Lar_restr_allev PF14354.6 AAAP01001764.1_2 - 9.2 6.7 6.3 0.7 10.3 0.3 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar B12-binding PF02310.19 AAAP01001765.1_1 - 4.5e-15 55.8 0.8 6.1e-15 55.3 0.8 1.2 1 0 0 1 1 1 1 B12 binding domain NTP_transferase PF00483.23 AAAP01001765.1_2 - 2.5e-28 99.3 0.1 2.8e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01001765.1_2 - 2.1e-06 28.2 2.0 2.5e-06 27.9 2.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain Anth_synt_I_N PF04715.13 AAAP01001766.1_1 - 1e-12 48.5 0.0 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Rotamase_2 PF13145.6 AAAP01001766.1_2 - 2.3e-12 47.8 8.5 0.00012 22.9 0.0 3.3 3 0 0 3 3 3 3 PPIC-type PPIASE domain HTH_31 PF13560.6 AAAP01001766.1_2 - 0.064 13.6 0.6 0.31 11.4 0.5 2.3 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 AAAP01001766.1_2 - 0.095 12.6 0.3 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01001766.1_2 - 0.15 11.9 0.4 20 5.2 0.0 2.6 1 1 1 2 2 2 0 Homeodomain-like domain MDMPI_N PF11716.8 AAAP01001766.1_2 - 1.9 9.2 7.1 0.1 13.3 1.4 1.8 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain FUSC PF04632.12 AAAP01001768.1_2 - 8.3e-05 21.3 5.2 8.3e-05 21.3 5.2 1.6 2 0 0 2 2 2 1 Fusaric acid resistance protein family HrcA PF01628.21 AAAP01001769.1_1 - 4.4e-32 111.8 0.0 4.9e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 HrcA protein C terminal domain HrcA PF01628.21 AAAP01001769.1_2 - 1.5e-21 77.4 0.0 1.8e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain Ribosomal_L5 PF00281.19 AAAP01001769.1_2 - 0.15 12.4 0.1 0.71 10.3 0.1 1.9 1 1 1 2 2 2 0 Ribosomal protein L5 TM1506 PF08973.10 AAAP01001769.1_2 - 0.19 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) DUF1843 PF08898.10 AAAP01001770.1_1 - 0.065 13.7 3.0 0.11 13.0 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1843) AbiEi_4 PF13338.6 AAAP01001770.1_1 - 0.25 11.5 3.4 3.1 8.0 1.5 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Acyl-CoA_dh_1 PF00441.24 AAAP01001771.1_1 - 1.4e-36 125.9 1.2 1.6e-36 125.8 1.2 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01001771.1_1 - 5.6e-15 55.8 1.5 6.1e-15 55.7 1.5 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Biotin_carb_N PF00289.22 AAAP01001771.1_1 - 0.031 14.8 0.1 0.036 14.6 0.1 1.3 1 1 0 1 1 1 0 Biotin carboxylase, N-terminal domain MaoC_dehydratas PF01575.19 AAAP01001771.1_2 - 6.1e-23 80.7 0.0 9e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01001771.1_2 - 0.088 12.9 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase HpcH_HpaI PF03328.14 AAAP01001771.1_3 - 4.4e-18 65.2 4.1 4.5e-17 61.9 4.1 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01001771.1_3 - 0.011 15.0 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold HATPase_c PF02518.26 AAAP01001772.1_1 - 9.7e-20 71.2 0.0 1.5e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01001772.1_1 - 4.9e-09 36.1 0.1 2.2e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01001772.1_1 - 1.4e-05 25.0 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF874 PF05917.11 AAAP01001772.1_1 - 0.0019 17.3 2.7 0.25 10.3 1.3 2.1 2 0 0 2 2 2 2 Helicobacter pylori protein of unknown function (DUF874) HATPase_c_3 PF13589.6 AAAP01001772.1_1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01001772.1_1 - 0.019 14.9 0.0 0.072 13.0 0.0 2.0 3 0 0 3 3 3 0 GHKL domain Sugarporin_N PF11471.8 AAAP01001772.1_1 - 0.051 13.5 0.2 0.097 12.6 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ThiC_Rad_SAM PF01964.18 AAAP01001773.1_1 - 1.1e-50 172.7 0.0 1.2e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AAAP01001773.1_1 - 1.2e-16 60.3 0.1 2.4e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 ThiC-associated domain Lipoprotein_Ltp PF07553.11 AAAP01001774.1_1 - 1.7e-09 37.7 0.7 6.1e-09 36.0 0.1 2.2 2 0 0 2 2 2 1 Host cell surface-exposed lipoprotein RNA_pol_Rpc4 PF05132.14 AAAP01001774.1_1 - 0.044 14.2 0.3 0.057 13.9 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Calici_coat PF00915.20 AAAP01001774.1_1 - 0.23 10.3 1.2 0.32 9.8 1.2 1.3 1 0 0 1 1 1 0 Calicivirus coat protein Cupin_2 PF07883.11 AAAP01001774.1_2 - 1.2e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAAP01001774.1_2 - 4.3e-05 23.4 0.0 5.3e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AAAP01001774.1_2 - 0.043 13.5 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Methyltransf_31 PF13847.6 AAAP01001776.1_1 - 3.3e-07 30.2 0.1 3.9e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01001776.1_1 - 7.4e-05 23.4 0.0 9.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01001776.1_1 - 0.00054 19.8 0.0 0.00062 19.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01001776.1_1 - 0.00094 18.8 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAAP01001776.1_1 - 0.0025 18.5 0.0 0.0033 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAAP01001776.1_1 - 0.0039 16.8 0.0 0.0047 16.6 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 AAAP01001776.1_1 - 0.0053 16.5 0.0 0.0058 16.3 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 AAAP01001776.1_1 - 0.0054 17.3 0.0 0.0075 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01001776.1_1 - 0.0057 16.0 0.0 0.0063 15.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 AAAP01001776.1_1 - 0.011 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 AAAP01001776.1_1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 AAAP01001776.1_1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 AAAP01001776.1_1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 AAAP01001776.1_1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain P5CR_dimer PF14748.6 AAAP01001777.1_1 - 0.00091 19.5 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation DUF4510 PF14971.6 AAAP01001777.1_1 - 0.048 14.0 0.3 0.052 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Acetyltransf_4 PF13420.7 AAAP01001777.1_2 - 1.1e-12 48.4 0.0 2.9e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01001777.1_2 - 1.1e-09 38.5 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01001777.1_2 - 1.2e-06 28.8 0.0 1.8e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01001777.1_2 - 4.9e-05 24.0 0.0 6.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01001777.1_2 - 0.0017 18.3 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01001777.1_2 - 0.0052 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF4235 PF14019.6 AAAP01001777.1_2 - 0.0091 16.1 2.4 0.02 15.0 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) Acetyltransf_CG PF14542.6 AAAP01001777.1_2 - 0.12 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribul_P_3_epim PF00834.19 AAAP01001777.1_3 - 3.9e-76 254.9 0.0 4.6e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AAAP01001777.1_3 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 AAAP01001777.1_3 - 0.017 14.5 0.1 0.04 13.4 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein OMPdecase PF00215.24 AAAP01001777.1_3 - 0.12 12.0 1.1 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribosomal_L34 PF00468.17 AAAP01001778.1_1 - 1.4e-22 79.3 7.9 1.4e-22 79.3 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 DUF1465 PF07323.12 AAAP01001778.1_2 - 3.3e-08 33.5 0.1 3.8e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) tRNA-synt_1d PF00750.19 AAAP01001779.1_1 - 6.8e-10 38.4 0.0 4.1e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1 PF00133.22 AAAP01001779.1_1 - 9.4e-07 27.5 0.0 0.00064 18.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01001779.1_1 - 0.00017 20.4 0.0 0.041 12.6 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AAAP01001779.1_1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAAP01001779.1_1 - 0.0066 15.4 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) Arg_tRNA_synt_N PF03485.16 AAAP01001779.1_2 - 1.7e-22 79.8 0.0 3.2e-22 78.9 0.0 1.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain PepSY_2 PF13670.6 AAAP01001781.1_2 - 0.098 12.7 1.5 0.092 12.8 1.5 1.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain NTP_transf_3 PF12804.7 AAAP01001782.1_1 - 1.7e-35 122.8 10.9 2.1e-35 122.5 10.9 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01001782.1_1 - 4.4e-07 29.9 0.2 5.9e-07 29.5 0.2 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Catalase PF00199.19 AAAP01001782.1_2 - 4.3e-16 59.0 0.0 5.6e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Aconitase_C PF00694.19 AAAP01001783.1_1 - 2.9e-42 144.1 0.0 3.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Apolipoprotein PF01442.18 AAAP01001784.1_1 - 9.3e-12 45.2 24.0 7.2e-08 32.5 12.5 2.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 AAAP01001784.1_1 - 0.00011 22.2 4.2 3.5 7.7 0.0 3.6 2 1 2 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 AAAP01001784.1_1 - 0.00016 21.5 0.9 0.23 11.3 0.1 4.1 2 1 3 5 5 5 1 CdvA-like coiled-coil domain DUF2884 PF11101.8 AAAP01001784.1_1 - 0.0012 18.4 0.1 0.57 9.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2884) GAS PF13851.6 AAAP01001784.1_1 - 0.024 14.0 0.3 3.3 7.0 0.0 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Collagen_mid PF15984.5 AAAP01001784.1_1 - 0.05 13.3 0.4 0.53 10.0 0.1 2.2 1 1 1 2 2 2 0 Bacterial collagen, middle region TMEM65 PF10507.9 AAAP01001784.1_1 - 0.16 11.9 0.1 0.41 10.6 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 65 TetR_C_31 PF17940.1 AAAP01001785.1_1 - 7.3e-08 32.6 3.5 8.5e-08 32.4 3.5 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 AAAP01001785.1_1 - 0.00079 19.8 0.8 0.00092 19.6 0.8 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAAP01001785.1_1 - 0.015 15.6 2.1 0.25 11.6 2.1 2.0 1 1 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Acetyltransf_3 PF13302.7 AAAP01001785.1_2 - 7.2e-32 111.0 0.0 8.4e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01001785.1_2 - 3.7e-10 40.1 0.0 4.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAAP01001785.1_2 - 0.00011 21.8 0.1 0.00023 20.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01001785.1_2 - 0.0026 17.7 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Lipocalin_5 PF13924.6 AAAP01001786.1_1 - 7.6e-34 116.5 0.0 1e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain PS_pyruv_trans PF04230.13 AAAP01001787.1_1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase CAV_VP3 PF04771.12 AAAP01001788.1_1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.0 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein A_deaminase PF00962.22 AAAP01001788.1_4 - 3.4e-23 82.5 0.0 3.9e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Zincin_1 PF06262.11 AAAP01001789.1_1 - 5.4e-12 45.7 0.0 9.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Zincin-like metallopeptidase DUF3499 PF12005.8 AAAP01001789.1_2 - 2.2e-46 157.5 2.4 4.7e-46 156.4 2.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3499) NMT1 PF09084.11 AAAP01001790.1_1 - 6.5e-20 72.0 0.1 8.5e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAAP01001790.1_1 - 4.7e-15 56.0 0.0 6.2e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAAP01001790.1_1 - 2.4e-10 40.2 0.1 3.4e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAAP01001790.1_1 - 4.2e-06 26.4 0.1 8.2e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01001790.1_1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein dDENN PF03455.19 AAAP01001790.1_1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 dDENN domain BPD_transp_1 PF00528.22 AAAP01001790.1_2 - 6.8e-19 68.3 14.6 1.2e-18 67.5 14.6 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Ank_2 PF12796.7 AAAP01001791.1_1 - 1.1e-26 93.3 0.0 3.7e-16 59.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AAAP01001791.1_1 - 1.3e-15 57.5 0.4 9.3e-07 29.3 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 AAAP01001791.1_1 - 5e-15 55.4 0.9 4.5e-08 33.2 0.1 2.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 AAAP01001791.1_1 - 1.1e-13 51.0 0.2 6.3e-06 26.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 AAAP01001791.1_1 - 1.2e-12 46.8 0.0 5.3e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat FGGY_N PF00370.21 AAAP01001791.1_2 - 7.8e-08 32.2 0.0 7.9e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 AAAP01001791.1_2 - 0.0042 16.6 0.0 0.0042 16.6 0.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 AAAP01001791.1_2 - 0.093 12.2 0.0 0.093 12.2 0.0 1.0 1 0 0 1 1 1 0 ROK family HupE_UreJ PF04955.12 AAAP01001792.1_1 - 1.6e-29 102.6 15.2 1.8e-29 102.5 15.2 1.0 1 0 0 1 1 1 1 HupE / UreJ protein DUF3606 PF12244.8 AAAP01001792.1_2 - 5.1e-18 64.8 0.8 6.4e-18 64.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3606) HhH-GPD PF00730.25 AAAP01001793.1_1 - 1.7e-18 67.0 0.0 3e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAAP01001793.1_1 - 0.00089 19.0 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAAP01001793.1_1 - 0.059 13.7 10.6 0.1 13.0 10.6 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF2244 PF10003.9 AAAP01001793.1_2 - 6e-45 152.3 0.8 6.8e-45 152.2 0.8 1.0 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) ABM PF03992.16 AAAP01001794.1_1 - 2.5e-13 49.9 0.1 3.6e-13 49.4 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Hydrolase_4 PF12146.8 AAAP01001794.1_2 - 0.0015 17.8 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2865 PF11064.8 AAAP01001795.1_2 - 3e-18 66.3 0.1 5.7e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2865) ECH_1 PF00378.20 AAAP01001796.1_1 - 1.4e-17 63.9 0.0 2e-15 56.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01001796.1_1 - 1.4e-10 41.2 0.0 3.7e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF5558 PF17713.1 AAAP01001796.1_1 - 0.072 13.5 3.3 1.3 9.4 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5558) EamA PF00892.20 AAAP01001796.1_2 - 1e-16 61.3 22.3 6.8e-13 49.0 14.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family AAA_lid_2 PF17863.1 AAAP01001798.1_1 - 1.3e-13 50.6 2.3 1.3e-13 50.6 2.3 1.9 2 0 0 2 2 2 1 AAA lid domain Mg_chelatase PF01078.21 AAAP01001798.1_1 - 2.3e-11 43.5 0.4 3.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAAP01001798.1_1 - 3e-07 30.5 0.0 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MCM PF00493.23 AAAP01001798.1_1 - 2.2e-05 23.7 0.0 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 AAAP01001798.1_1 - 2.5e-05 24.6 0.2 0.00018 21.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01001798.1_1 - 0.00012 22.5 0.8 0.00028 21.3 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 AAAP01001798.1_1 - 0.00035 20.3 0.0 0.028 14.1 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_29 PF13555.6 AAAP01001798.1_1 - 0.0011 18.7 0.1 0.003 17.3 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 AAAP01001798.1_1 - 0.0061 17.0 0.0 0.051 14.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 AAAP01001798.1_1 - 0.0063 15.7 0.1 0.02 14.1 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Helicase_RecD PF05127.14 AAAP01001798.1_1 - 0.024 14.5 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Helicase AAA_30 PF13604.6 AAAP01001798.1_1 - 0.065 13.0 0.3 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAAP01001798.1_1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01001798.1_1 - 0.2 12.1 0.0 0.34 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 AAAP01001798.1_1 - 0.21 10.3 0.1 4.1 6.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase_C PF13335.6 AAAP01001798.1_1 - 0.27 11.9 2.5 0.84 10.3 1.7 2.1 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Metalloenzyme PF01676.18 AAAP01001799.1_1 - 1.2e-23 83.8 0.0 1.2e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 AAAP01001799.1_1 - 0.098 11.6 0.1 4.7 6.1 0.0 2.0 1 1 1 2 2 2 0 Alkaline phosphatase Trans_reg_C PF00486.28 AAAP01001800.1_1 - 4.1e-21 74.8 0.0 6.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF3297 PF11730.8 AAAP01001800.1_2 - 2.1e-40 136.5 0.0 2.3e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3297) IucA_IucC PF04183.12 AAAP01001801.1_1 - 6.5e-30 104.4 0.3 1.2e-29 103.6 0.3 1.4 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 AAAP01001801.1_1 - 4.4e-29 102.0 1.4 8.4e-29 101.1 1.4 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter HemolysinCabind PF00353.19 AAAP01001802.1_1 - 2.9e-05 23.9 13.1 0.00011 22.1 7.6 2.2 1 1 1 2 2 2 2 RTX calcium-binding nonapeptide repeat (4 copies) HemolysinCabind PF00353.19 AAAP01001802.1_2 - 2.4e-15 56.2 96.7 7.2e-07 29.1 10.5 7.6 5 3 1 6 6 6 6 RTX calcium-binding nonapeptide repeat (4 copies) ApbA_C PF08546.11 AAAP01001803.1_1 - 4.5e-14 52.7 0.0 5e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal SSB PF00436.25 AAAP01001804.1_2 - 4.1e-20 71.8 0.6 4.6e-20 71.6 0.6 1.0 1 0 0 1 1 1 1 Single-strand binding protein family ADH_zinc_N_2 PF13602.6 AAAP01001804.1_3 - 3.3e-05 24.9 0.0 3.5e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Isochorismatase PF00857.20 AAAP01001805.1_2 - 2.8e-31 109.0 0.0 4.3e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Gly_transf_sug PF04488.15 AAAP01001806.1_2 - 2.8e-06 27.9 0.0 4.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 AAAP01001806.1_2 - 0.0033 16.9 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 AAAP01001806.1_2 - 0.0072 15.7 0.0 0.041 13.2 0.0 1.9 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Porin_2 PF02530.14 AAAP01001807.1_2 - 1.2e-23 84.0 0.4 1.4e-23 83.8 0.4 1.1 1 0 0 1 1 1 1 Porin subfamily FtsK_4TM PF13491.6 AAAP01001808.1_1 - 9e-08 32.0 6.5 1.3e-07 31.5 6.5 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE DUF4131 PF13567.6 AAAP01001808.1_1 - 1.8 8.2 6.1 72 3.0 6.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Sigma70_r4_2 PF08281.12 AAAP01001809.1_1 - 5.1e-09 35.7 0.0 5.1e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01001809.1_1 - 7.9e-07 28.5 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01001809.1_1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain H_PPase PF03030.16 AAAP01001809.1_2 - 2.5e-19 69.4 0.0 3.1e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase EI24 PF07264.11 AAAP01001809.1_2 - 0.0089 16.3 0.4 0.012 15.9 0.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3180 PF11377.8 AAAP01001809.1_2 - 0.77 9.9 13.3 2.1 8.5 13.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) DUF1616 PF07760.11 AAAP01001809.1_2 - 1.4 8.2 4.4 0.72 9.2 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) UL42 PF17638.2 AAAP01001809.1_2 - 3.5 7.6 4.1 33 4.5 1.8 2.1 1 1 1 2 2 2 0 HCMV UL42 HisKA_3 PF07730.13 AAAP01001810.1_1 - 1.8e-16 60.4 6.6 1.8e-16 60.4 6.6 2.9 3 0 0 3 3 3 1 Histidine kinase CoA_binding_3 PF13727.6 AAAP01001810.1_1 - 0.029 14.4 0.5 0.55 10.2 0.0 2.2 1 1 0 2 2 2 0 CoA-binding domain DUF3829 PF12889.7 AAAP01001810.1_1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Glyco_trans_1_4 PF13692.6 AAAP01001811.1_2 - 3.5e-27 95.5 0.1 2.2e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01001811.1_2 - 4.1e-05 23.2 0.0 9.1e-05 22.1 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01001811.1_2 - 0.00086 19.6 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 NAD_binding_4 PF07993.12 AAAP01001812.1_1 - 1.8e-21 76.5 0.0 2.5e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 AAAP01001812.1_1 - 1.7e-06 27.7 0.0 3.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01001812.1_1 - 0.0013 18.2 0.0 0.0067 15.9 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Zn_ribbon_17 PF17120.5 AAAP01001812.1_1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HD_assoc PF13286.6 AAAP01001813.1_1 - 2.1e-15 57.0 0.1 4.8e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 Phosphohydrolase-associated domain LPP PF04728.13 AAAP01001813.1_1 - 8.4 6.9 6.9 6.5 7.2 0.2 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Transposase_20 PF02371.16 AAAP01001814.1_1 - 1.4e-22 79.8 1.6 2.6e-22 78.9 0.2 1.9 1 1 1 2 2 2 1 Transposase IS116/IS110/IS902 family Wzy_C PF04932.15 AAAP01001816.1_1 - 1.6e-10 40.8 1.9 1.6e-10 40.8 1.9 2.5 2 0 0 2 2 2 1 O-Antigen ligase GCS2 PF04107.13 AAAP01001818.1_1 - 3.5e-40 138.2 0.0 5.1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Asparaginase_C PF17763.1 AAAP01001818.1_2 - 3.4e-13 49.8 0.0 3.5e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain GatB_N PF02934.15 AAAP01001819.1_1 - 1.3e-46 159.2 0.0 1.5e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 GatB/GatE catalytic domain Band_7 PF01145.25 AAAP01001820.1_1 - 2.2e-30 106.0 1.9 2.2e-30 106.0 1.9 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 AAAP01001820.1_1 - 0.34 11.1 5.5 0.2 11.9 0.5 2.7 3 0 0 3 3 3 0 Flotillin FAD_binding_3 PF01494.19 AAAP01001821.1_1 - 2.1e-08 33.8 1.2 2.3e-08 33.7 1.2 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01001821.1_1 - 6.2e-07 28.9 0.9 7.4e-07 28.7 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01001821.1_1 - 1.5e-06 28.3 2.1 1.5e-06 28.3 2.1 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01001821.1_1 - 1.6e-05 24.2 4.0 1.6e-05 24.2 4.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAAP01001821.1_1 - 2e-05 25.0 1.6 7.9e-05 23.2 1.3 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01001821.1_1 - 2.3e-05 24.2 5.1 2.3e-05 24.2 5.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAAP01001821.1_1 - 0.00034 20.1 2.1 0.00044 19.7 2.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAAP01001821.1_1 - 0.00051 19.3 0.3 0.0018 17.5 0.7 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 AAAP01001821.1_1 - 0.0025 16.6 0.9 0.0031 16.3 0.9 1.1 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 AAAP01001821.1_1 - 0.0032 16.4 2.4 0.0037 16.2 2.4 1.1 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 AAAP01001821.1_1 - 0.0033 16.6 2.4 0.0038 16.4 2.4 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 AAAP01001821.1_1 - 0.0044 16.7 0.8 0.0044 16.7 0.8 2.1 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 AAAP01001821.1_1 - 0.008 15.5 0.2 0.01 15.2 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01001821.1_1 - 0.02 14.2 2.5 0.027 13.8 2.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAAP01001821.1_1 - 0.024 13.9 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CclA_1 PF16942.5 AAAP01001821.1_1 - 0.12 12.6 1.0 0.24 11.7 1.0 1.5 1 0 0 1 1 1 0 Putative cyclic bacteriocin 3HCDH_N PF02737.18 AAAP01001821.1_1 - 0.24 11.2 0.9 0.33 10.8 0.9 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AAAP01001821.1_1 - 0.57 10.0 5.3 1.3 8.9 2.1 2.2 1 1 1 2 2 2 0 Rossmann-like domain zf-CHCC PF10276.9 AAAP01001821.1_2 - 3.9e-11 42.8 0.3 6.2e-11 42.2 0.1 1.4 2 0 0 2 2 2 1 Zinc-finger domain PknG_rubred PF16919.5 AAAP01001821.1_2 - 0.087 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Kelch_1 PF01344.25 AAAP01001821.1_2 - 0.18 11.4 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Peptidase_M24 PF00557.24 AAAP01001821.1_3 - 4.5e-20 72.2 0.0 5.4e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Flagellin_C PF00700.21 AAAP01001822.1_1 - 7e-08 32.7 6.8 7e-08 32.7 6.8 2.1 2 1 0 2 2 2 1 Bacterial flagellin C-terminal helical region KOW PF00467.29 AAAP01001823.1_1 - 1e-05 25.3 1.7 1.4e-05 24.8 1.7 1.2 1 0 0 1 1 1 1 KOW motif Redoxin PF08534.10 AAAP01001824.1_1 - 1.9e-17 63.3 0.0 2.5e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01001824.1_1 - 3e-13 49.8 0.0 4.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAAP01001824.1_1 - 2.1e-08 34.4 0.0 3.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AAAP01001824.1_1 - 7.1e-07 29.2 0.0 7.8e-06 25.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin SCO1-SenC PF02630.14 AAAP01001824.1_1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC GSHPx PF00255.19 AAAP01001824.1_1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione peroxidase Thioredoxin_2 PF13098.6 AAAP01001824.1_1 - 0.12 12.9 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain SWIB PF02201.18 AAAP01001825.1_1 - 1.9e-29 101.3 0.1 2.5e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 SWIB/MDM2 domain adh_short_C2 PF13561.6 AAAP01001825.1_2 - 1.5e-19 70.5 0.2 3.4e-19 69.3 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001825.1_2 - 5.3e-06 26.0 0.1 7.9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase WzyE PF06899.11 AAAP01001826.1_1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase GGDEF PF00990.21 AAAP01001827.1_2 - 1.8e-41 141.6 0.0 2.4e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Pyr_redox_dim PF02852.22 AAAP01001828.1_1 - 6.2e-26 90.8 0.0 8e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Aldo_ket_red PF00248.21 AAAP01001829.1_1 - 3.6e-08 32.9 0.0 3.9e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Crp_2 PF13545.6 AAAP01001829.1_2 - 9.3e-15 54.4 0.6 9.3e-15 54.4 0.6 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01001829.1_2 - 8.1e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Crp PF00325.20 AAAP01001829.1_2 - 0.00058 19.5 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 AAAP01001829.1_2 - 0.01 15.7 2.2 0.011 15.6 0.3 2.1 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAAP01001829.1_2 - 0.043 14.3 0.0 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain Citrate_synt PF00285.21 AAAP01001830.1_1 - 1.5e-08 34.2 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CheW PF01584.19 AAAP01001831.1_1 - 4e-14 52.4 2.7 4.2e-13 49.1 2.5 2.1 2 0 0 2 2 2 1 CheW-like domain HATPase_c PF02518.26 AAAP01001831.1_1 - 6.1e-11 42.8 0.0 1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STAS_2 PF13466.6 AAAP01001831.1_1 - 0.0005 20.3 0.1 0.0016 18.7 0.1 1.9 1 0 0 1 1 1 1 STAS domain AAA_31 PF13614.6 AAAP01001831.1_2 - 1.6e-33 116.1 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01001831.1_2 - 3.8e-14 52.8 0.1 2.3e-13 50.3 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAAP01001831.1_2 - 1.6e-08 34.2 1.0 4.6e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 ATPase MipZ ParA PF10609.9 AAAP01001831.1_2 - 2.3e-07 30.5 0.9 9.6e-07 28.5 0.2 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AAAP01001831.1_2 - 1.5e-06 27.9 0.0 3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 AAAP01001831.1_2 - 0.0001 21.7 0.4 0.3 10.4 0.0 2.1 2 0 0 2 2 2 2 VirC1 protein ArsA_ATPase PF02374.15 AAAP01001831.1_2 - 0.00028 20.2 0.6 0.18 11.0 0.2 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase Fer4_NifH PF00142.18 AAAP01001831.1_2 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family LpxK PF02606.14 AAAP01001831.1_2 - 0.0062 15.7 0.3 0.0083 15.3 0.3 1.2 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Glyco_transf_4 PF13439.6 AAAP01001831.1_2 - 0.0066 16.5 1.2 0.029 14.4 1.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 COX1 PF00115.20 AAAP01001831.1_2 - 0.099 11.5 0.5 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I SRP54 PF00448.22 AAAP01001831.1_2 - 0.14 11.8 0.1 0.99 9.0 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4235 PF14019.6 AAAP01001832.1_1 - 5e-08 32.9 0.3 5.2e-08 32.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) SDH_C PF18317.1 AAAP01001832.1_1 - 0.015 15.1 0.6 0.031 14.0 0.6 1.5 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Response_reg PF00072.24 AAAP01001832.1_2 - 1.7e-28 99.0 0.1 2.4e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01001832.1_2 - 1.3e-08 34.3 0.0 2.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HisKA_3 PF07730.13 AAAP01001832.1_3 - 1.2e-07 32.1 0.5 3.5e-07 30.7 0.3 1.9 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AAAP01001832.1_3 - 0.00082 19.9 0.2 0.0023 18.4 0.1 1.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01001832.1_3 - 0.0067 16.4 0.3 0.015 15.3 0.2 1.7 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain CorA PF01544.18 AAAP01001833.1_1 - 2.1e-11 43.7 0.0 2.7e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_15 PF00723.21 AAAP01001833.1_1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Glyco_hydro_3 PF00933.21 AAAP01001834.1_1 - 1.1e-69 235.2 0.0 1.4e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ATE_N PF04376.13 AAAP01001835.1_1 - 9.7e-17 61.1 0.2 1.2e-16 60.8 0.2 1.1 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus RDD PF06271.12 AAAP01001835.1_2 - 7e-06 26.3 0.1 7.5e-06 26.2 0.1 1.0 1 0 0 1 1 1 1 RDD family DnaB_bind PF10410.9 AAAP01001836.1_3 - 0.048 13.8 0.5 6.9 6.9 0.0 2.9 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Alpha-amylase PF00128.24 AAAP01001837.1_1 - 8.4e-12 45.3 0.0 1e-06 28.6 0.0 3.0 2 1 1 3 3 3 3 Alpha amylase, catalytic domain Aminotran_1_2 PF00155.21 AAAP01001837.1_1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3459 PF11941.8 AAAP01001837.1_2 - 1.7e-12 47.5 0.1 2.8e-12 46.8 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Glyco_hydro_43 PF04616.14 AAAP01001838.1_1 - 5.1e-09 35.9 0.9 7.4e-09 35.3 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SBP_bac_8 PF13416.6 AAAP01001839.1_1 - 7.8e-39 134.2 3.0 9.8e-39 133.8 3.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01001839.1_1 - 4.1e-29 102.5 4.5 4.1e-29 102.5 4.5 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAAP01001839.1_1 - 0.00084 18.8 4.0 0.0028 17.1 1.5 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein PriA_C PF18074.1 AAAP01001840.1_1 - 3.1e-19 69.6 0.0 5.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain Helicase_C PF00271.31 AAAP01001840.1_1 - 0.0003 21.1 0.0 0.00062 20.1 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Response_reg PF00072.24 AAAP01001841.1_1 - 1.7e-14 54.0 0.0 1.8e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Glutaredoxin PF00462.24 AAAP01001841.1_2 - 1.1e-20 73.6 0.0 1.3e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 AAAP01001841.1_2 - 0.0058 16.8 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF836 PF05768.14 AAAP01001841.1_2 - 0.012 16.0 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 AAAP01001841.1_2 - 0.016 15.7 0.0 0.049 14.1 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin-like domain Redoxin PF08534.10 AAAP01001841.1_2 - 0.02 14.6 0.5 0.025 14.3 0.5 1.3 1 1 0 1 1 1 0 Redoxin GST_N_2 PF13409.6 AAAP01001841.1_2 - 0.12 12.7 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CN_hydrolase PF00795.22 AAAP01001841.1_3 - 6e-15 55.3 0.0 7.3e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AC_N PF16214.5 AAAP01001842.1_2 - 0.066 12.3 3.2 0.07 12.2 3.2 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2127 PF09900.9 AAAP01001842.1_2 - 0.43 10.9 7.6 0.24 11.7 3.5 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2127) Sugar_tr PF00083.24 AAAP01001843.1_1 - 3.7e-25 88.7 5.5 4.6e-25 88.4 5.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAAP01001843.1_1 - 2.8e-18 66.0 14.9 3.5e-18 65.7 14.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Arginase PF00491.21 AAAP01001844.1_1 - 0.00011 21.9 0.0 0.00011 21.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aconitase_C PF00694.19 AAAP01001844.1_2 - 2.6e-21 76.3 0.1 3.9e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain E1_FCCH PF16190.5 AAAP01001844.1_2 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Peptidase_M20 PF01546.28 AAAP01001845.1_1 - 4.3e-25 88.6 0.3 5.4e-25 88.3 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAAP01001845.1_1 - 2.3e-09 37.1 0.4 6e-09 35.8 0.4 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Aminotran_5 PF00266.19 AAAP01001848.1_1 - 6.4e-19 68.1 0.0 8.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01001848.1_1 - 9.3e-06 24.4 0.0 1.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01001848.1_1 - 0.0003 20.2 0.4 0.00044 19.7 0.4 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ISAV_HA PF06215.11 AAAP01001848.1_1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin MoaC PF01967.21 AAAP01001849.1_1 - 7.2e-24 84.4 0.1 7.9e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 MoaC family MoeA_N PF03453.17 AAAP01001849.1_2 - 1.1e-40 139.0 3.4 1.3e-40 138.8 2.8 1.4 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAAP01001849.1_2 - 1.8e-16 60.1 0.0 2.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain AP_endonuc_2 PF01261.24 AAAP01001849.1_2 - 0.066 12.7 0.0 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Molybdopterin PF00384.22 AAAP01001850.1_1 - 2.4e-08 33.4 0.0 2.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Transgly PF00912.22 AAAP01001851.1_1 - 1.9e-60 203.4 0.0 3.1e-60 202.7 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase DUF2313 PF10076.9 AAAP01001851.1_1 - 0.07 13.0 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) Prenyltransf PF01255.19 AAAP01001853.1_2 - 6.4e-68 228.6 0.0 7.8e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4096 PF13340.6 AAAP01001854.1_1 - 1.5e-19 70.0 4.7 2.5e-19 69.2 4.7 1.4 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) FliT PF05400.13 AAAP01001854.1_1 - 0.067 14.0 0.3 0.21 12.4 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FliT DDE_Tnp_1 PF01609.21 AAAP01001854.1_2 - 1.2e-09 38.2 0.0 1.3e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAAP01001854.1_2 - 0.0068 16.8 0.1 0.0085 16.5 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain Sugar_tr PF00083.24 AAAP01001855.1_1 - 5.6e-07 28.8 4.5 6.9e-07 28.5 4.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAAP01001855.1_1 - 0.0012 17.9 16.0 0.0024 16.8 15.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily YrhK PF14145.6 AAAP01001855.1_1 - 3.1 7.7 9.1 14 5.7 6.2 2.8 2 1 1 3 3 3 0 YrhK-like protein OppC_N PF12911.7 AAAP01001856.1_1 - 0.00017 21.5 0.6 0.00017 21.5 0.6 2.7 2 1 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AAAP01001856.1_1 - 0.0012 18.6 11.5 0.0013 18.5 10.0 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF805 PF05656.14 AAAP01001856.1_1 - 3.6 8.0 6.6 1.6 9.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Phage_holin_2_3 PF16080.5 AAAP01001856.1_1 - 7.9 6.3 9.0 0.59 9.9 1.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family HP1 AAA_5 PF07728.14 AAAP01001857.1_1 - 4.6e-10 39.6 0.1 1e-09 38.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01001857.1_1 - 4.5e-09 36.8 0.0 8.3e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01001857.1_1 - 8.1e-08 32.6 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AAAP01001857.1_1 - 4.8e-05 23.1 0.0 0.0056 16.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 AAAP01001857.1_1 - 6.5e-05 23.4 0.8 0.0005 20.5 0.8 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 AAAP01001857.1_1 - 0.00025 21.2 0.0 0.00032 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 AAAP01001857.1_1 - 0.0005 19.8 0.0 0.00079 19.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AAAP01001857.1_1 - 0.00066 19.6 0.3 0.0036 17.2 0.1 1.9 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 AAAP01001857.1_1 - 0.0012 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AAAP01001857.1_1 - 0.0015 18.8 0.7 0.026 14.9 0.7 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 AAAP01001857.1_1 - 0.0022 17.2 0.2 0.015 14.5 0.1 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 AAAP01001857.1_1 - 0.0034 16.9 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 AAAP01001857.1_1 - 0.0043 16.3 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 AAAP01001857.1_1 - 0.0066 17.0 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01001857.1_1 - 0.0086 16.2 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01001857.1_1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 AAAP01001857.1_1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 AAAP01001857.1_1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.4 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 AAAP01001857.1_1 - 0.023 14.5 0.4 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 AAAP01001857.1_1 - 0.024 14.8 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 AAAP01001857.1_1 - 0.027 14.5 0.0 0.061 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AAAP01001857.1_1 - 0.052 13.4 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AAAP01001857.1_1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Voltage_CLC PF00654.20 AAAP01001858.1_1 - 1e-31 110.5 10.3 1.1e-31 110.4 10.3 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel DUF4381 PF14316.6 AAAP01001859.1_1 - 0.0052 17.0 2.4 0.0068 16.7 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) BatD PF13584.6 AAAP01001859.1_1 - 0.013 14.4 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance MFS_4 PF06779.14 AAAP01001859.1_1 - 0.016 14.5 2.7 0.02 14.2 2.7 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Tad PF13400.6 AAAP01001859.1_1 - 0.022 15.1 13.2 0.037 14.3 13.2 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like CcmH PF03918.14 AAAP01001859.1_1 - 0.066 12.5 1.3 0.092 12.0 1.3 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein MSC PF09402.10 AAAP01001859.1_1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain ABC_membrane PF00664.23 AAAP01001859.1_1 - 0.21 11.2 0.1 0.25 11.0 0.1 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region PulG PF11773.8 AAAP01001859.1_1 - 0.24 11.3 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin K_channel_TID PF07941.11 AAAP01001859.1_1 - 1 9.8 10.0 1.6 9.2 10.0 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TMEM100 PF16311.5 AAAP01001859.1_1 - 5.3 6.6 5.2 12 5.4 5.2 1.7 1 1 0 1 1 1 0 Transmembrane protein 100 NUDIX PF00293.28 AAAP01001860.1_1 - 5e-14 52.5 0.2 5.6e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Band_7 PF01145.25 AAAP01001860.1_2 - 4.8e-10 39.7 0.1 6.2e-10 39.4 0.1 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family FAD_binding_4 PF01565.23 AAAP01001860.1_2 - 0.0033 17.2 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Tudor_RapA PF18337.1 AAAP01001860.1_3 - 0.048 13.8 0.2 0.088 13.0 0.2 1.4 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain FAS_N PF17828.1 AAAP01001860.1_3 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta DNA_ligase_aden PF01653.18 AAAP01001861.1_1 - 4.6e-93 311.8 0.0 5.2e-93 311.6 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AAAP01001861.1_1 - 1.1e-09 38.1 0.7 2.5e-09 36.9 0.3 1.8 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain DUF3108 PF11306.8 AAAP01001862.1_2 - 1e-16 61.6 0.0 1.2e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3108) DEDD_Tnp_IS110 PF01548.17 AAAP01001863.1_1 - 9.3e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Transposase PATR PF12951.7 AAAP01001864.1_1 - 1e-07 31.9 0.2 1e-07 31.9 0.2 2.9 3 0 0 3 3 3 1 Passenger-associated-transport-repeat Lipase_GDSL PF00657.22 AAAP01001864.1_1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lactamase_B_2 PF12706.7 AAAP01001867.1_1 - 3.9e-05 23.3 0.1 4.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01001867.1_1 - 0.0014 18.6 0.6 0.0026 17.8 0.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Hpr_kinase_C PF07475.12 AAAP01001868.1_1 - 3e-11 43.1 0.0 3.7e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 AAAP01001868.1_1 - 0.00079 19.9 0.0 0.00083 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01001868.1_1 - 0.0024 17.6 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01001868.1_1 - 0.0086 16.4 0.0 0.0098 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01001868.1_1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AAAP01001868.1_1 - 0.062 13.2 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 AAAP01001868.1_1 - 0.087 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01001868.1_1 - 0.092 13.3 0.1 0.12 12.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01001868.1_1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 AAAP01001868.1_1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activat PF00158.26 AAAP01001868.1_1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.4 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 AAAP01001868.1_1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 AAAP01001868.1_1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TIP49 PF06068.13 AAAP01001868.1_1 - 0.16 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 AAAP01001868.1_1 - 0.16 12.4 0.0 0.19 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 AAAP01001868.1_1 - 0.2 10.9 0.0 0.2 10.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SMC_N PF02463.19 AAAP01001868.1_1 - 0.23 10.8 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain HATPase_c PF02518.26 AAAP01001868.1_2 - 9.6e-23 80.8 0.0 3.6e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01001868.1_2 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01001868.1_2 - 0.0038 17.2 3.0 0.18 11.8 1.3 2.6 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01001868.1_2 - 0.0041 17.1 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Rnk_N PF14760.6 AAAP01001868.1_2 - 0.023 15.2 3.5 0.073 13.6 2.4 2.3 2 0 0 2 2 2 0 Rnk N-terminus Mur_ligase_C PF02875.21 AAAP01001869.1_2 - 2.8e-18 66.0 0.0 6.7e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 AAAP01001869.1_2 - 0.019 14.9 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Glyco_hydro_3 PF00933.21 AAAP01001870.1_1 - 1.5e-12 47.6 0.3 1.6e-12 47.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Peripla_BP_3 PF13377.6 AAAP01001870.1_2 - 4.1e-36 124.8 3.5 1.1e-35 123.5 3.4 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 AAAP01001870.1_2 - 4.3e-21 75.6 0.2 7.4e-21 74.8 0.0 1.4 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 AAAP01001870.1_2 - 2.1e-14 53.8 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 AAAP01001870.1_2 - 6e-13 48.4 3.9 6.1e-13 48.3 1.5 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 AAAP01001870.1_2 - 5.6e-05 23.4 0.9 0.00057 20.2 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01001870.1_2 - 0.00046 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix YdaS_antitoxin PF15943.5 AAAP01001870.1_2 - 0.021 14.7 0.1 0.067 13.1 0.1 1.9 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 AAAP01001870.1_2 - 0.068 13.1 1.0 0.47 10.4 0.3 2.7 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 AAAP01001870.1_2 - 0.54 10.1 2.8 0.82 9.5 0.2 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain LpxB PF02684.15 AAAP01001871.1_1 - 2.7e-90 302.9 0.0 3.1e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase AAA_25 PF13481.6 AAAP01001871.1_1 - 0.022 14.4 0.1 0.056 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.6 AAAP01001871.1_1 - 0.67 10.6 2.8 0.99 10.1 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain HlyD_D23 PF16576.5 AAAP01001872.1_1 - 2e-07 30.5 0.2 4.2e-07 29.4 0.1 1.6 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAAP01001872.1_1 - 8e-06 25.7 1.0 1.2e-05 25.1 1.0 1.4 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS ACR_tran PF00873.19 AAAP01001872.1_2 - 2.9e-58 197.4 0.0 3.2e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF2183 PF09949.9 AAAP01001873.1_1 - 1.5e-30 105.5 0.0 2.1e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LEM PF03020.15 AAAP01001873.1_1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 LEM domain ACR_tran PF00873.19 AAAP01001874.1_1 - 1.3e-54 185.3 0.1 1.6e-54 185.1 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3606 PF12244.8 AAAP01001874.1_1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) NMT1_3 PF16868.5 AAAP01001875.1_1 - 3.8e-06 26.5 0.0 1.2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 NMT1-like family LysR_substrate PF03466.20 AAAP01001875.1_1 - 5.4e-05 22.6 1.3 0.001 18.5 0.1 2.4 1 1 1 2 2 2 1 LysR substrate binding domain NMT1 PF09084.11 AAAP01001875.1_1 - 0.00013 22.0 0.0 0.0011 19.0 0.0 2.5 2 1 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AAAP01001875.1_1 - 0.012 15.1 0.2 3 7.2 0.0 2.5 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 tRNA-synt_His PF13393.6 AAAP01001876.1_1 - 3.3e-11 43.0 0.0 3.4e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HisG PF01634.18 AAAP01001876.1_2 - 2.3e-36 125.2 0.0 3.2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase NPR1_like_C PF12313.8 AAAP01001876.1_2 - 0.045 13.3 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Formyl_trans_N PF00551.19 AAAP01001877.1_1 - 7.8e-08 32.3 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase AMP-binding PF00501.28 AAAP01001877.1_2 - 2.3e-24 85.8 0.0 3.4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01001877.1_2 - 3.2e-08 34.4 0.0 4.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Radical_SAM PF04055.21 AAAP01001878.1_2 - 9.9e-21 74.8 0.0 1.5e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAAP01001878.1_2 - 0.024 14.7 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 HemN C-terminal domain YacG PF03884.14 AAAP01001878.1_2 - 0.098 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG CheB_methylest PF01339.17 AAAP01001879.1_1 - 6.5e-26 91.1 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 CheB methylesterase HTH_12 PF08461.10 AAAP01001879.1_1 - 0.0043 17.0 0.3 0.0084 16.0 0.3 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain sCache_3_2 PF17203.4 AAAP01001880.1_1 - 4.6e-21 75.4 2.1 2.9e-20 72.8 0.1 2.6 2 1 1 3 3 3 1 Single cache domain 3 PAS_4 PF08448.10 AAAP01001880.1_1 - 2e-10 40.9 3.0 4.8e-10 39.7 1.7 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAAP01001880.1_1 - 5.4e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold SPOB_a PF14689.6 AAAP01001880.1_1 - 7e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain PAS_8 PF13188.7 AAAP01001880.1_1 - 1.4e-05 24.9 0.2 4.3e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAAP01001880.1_1 - 0.0061 16.8 0.0 0.01 16.0 0.0 1.5 1 1 0 1 1 1 1 PAS domain PAS_7 PF12860.7 AAAP01001880.1_1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold DUF4170 PF13773.6 AAAP01001881.1_1 - 2.5e-37 126.8 0.1 2.9e-37 126.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4170) Exonuc_VII_L PF02601.15 AAAP01001881.1_2 - 4e-15 56.2 0.0 4.6e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit Apolipoprotein PF01442.18 AAAP01001881.1_2 - 0.03 14.2 2.5 0.043 13.7 2.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MarR_2 PF12802.7 AAAP01001882.1_1 - 1.1e-15 57.2 0.5 3.4e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AAAP01001882.1_1 - 4.7e-09 36.1 0.1 8.3e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01001882.1_1 - 5.5e-08 33.2 0.7 1.8e-07 31.5 0.1 2.1 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAAP01001882.1_1 - 9.6e-07 28.3 0.0 2.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAAP01001882.1_1 - 0.00043 20.2 1.3 0.0017 18.3 0.1 2.1 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 AAAP01001882.1_1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 AAAP01001882.1_1 - 0.0017 18.4 0.1 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 AAAP01001882.1_1 - 0.0039 17.5 0.1 0.031 14.6 0.1 2.1 1 1 0 1 1 1 1 Transcriptional regulator B-block_TFIIIC PF04182.12 AAAP01001882.1_1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_IclR PF09339.10 AAAP01001882.1_1 - 0.019 14.7 0.2 0.058 13.2 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_34 PF13601.6 AAAP01001882.1_1 - 0.022 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 AAAP01001882.1_1 - 0.046 13.7 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_23 PF13384.6 AAAP01001882.1_1 - 0.066 13.0 0.1 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain RQC PF09382.10 AAAP01001882.1_1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 RQC domain Response_reg PF00072.24 AAAP01001882.1_2 - 1.1e-10 41.7 0.0 1.3e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_19 PF04672.12 AAAP01001883.1_1 - 0.04 13.4 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase TPR_16 PF13432.6 AAAP01001885.1_1 - 0.0075 16.9 5.5 0.0075 16.9 5.5 5.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01001885.1_1 - 2.8 8.3 13.8 1.3 9.3 0.7 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat PAS_3 PF08447.12 AAAP01001886.1_1 - 3.6e-37 126.5 5.9 6.1e-19 68.1 0.8 2.6 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AAAP01001886.1_1 - 1.5e-20 73.5 7.4 1.3e-12 47.9 0.8 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01001886.1_1 - 2e-16 60.2 0.0 2.1e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01001886.1_1 - 1.7e-15 57.0 0.0 3.6e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 AAAP01001886.1_1 - 2.1e-08 34.1 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01001886.1_1 - 9.9e-05 22.3 0.0 0.005 16.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 AAAP01001886.1_1 - 0.00049 20.2 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 2 PAS domain dCache_1 PF02743.18 AAAP01001886.1_1 - 0.033 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Cache domain 17kDa_Anti_2 PF16998.5 AAAP01001887.1_1 - 4e-11 42.9 0.1 5.4e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 17 kDa outer membrane surface antigen OEP PF02321.18 AAAP01001887.1_2 - 0.0019 18.0 0.4 0.0023 17.8 0.4 1.1 1 0 0 1 1 1 1 Outer membrane efflux protein GAF PF01590.26 AAAP01001888.1_1 - 3.3e-06 27.7 0.0 5.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAAP01001888.1_1 - 0.00011 22.6 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 AAAP01001888.1_1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF4158 PF13700.6 AAAP01001888.1_1 - 0.0057 16.5 1.2 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4158) PAS_3 PF08447.12 AAAP01001888.1_1 - 0.0087 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01001888.1_1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 AAAP01001888.1_1 - 1.2 9.4 4.3 0.75 10.1 0.3 2.4 2 1 0 2 2 2 0 PAS fold COX4_pro PF03626.14 AAAP01001888.1_2 - 8.5e-07 29.3 8.1 1.1e-06 28.9 8.1 1.2 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV DUF2231 PF09990.9 AAAP01001888.1_2 - 0.33 11.4 5.9 0.067 13.6 2.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) COX3 PF00510.18 AAAP01001888.1_3 - 7e-08 32.6 4.9 1.2e-07 31.9 4.9 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III AhpC-TSA PF00578.21 AAAP01001889.1_1 - 1.2e-23 83.4 0.0 1.4e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01001889.1_1 - 2.1e-09 37.3 0.0 2.2e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin Pyr_redox_2 PF07992.14 AAAP01001889.1_2 - 1.3e-19 70.6 0.0 1.5e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01001889.1_2 - 2.2e-11 44.1 0.1 4.4e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01001889.1_2 - 6.6e-09 35.4 0.0 7.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01001889.1_2 - 0.036 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMO-like PF00743.19 AAAP01001889.1_2 - 0.12 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like H2TH PF06831.14 AAAP01001889.1_2 - 0.17 11.9 0.0 16 5.5 0.0 2.2 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain K_oxygenase PF13434.6 AAAP01001889.1_2 - 0.23 10.5 0.2 0.39 9.8 0.2 1.5 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) PAS_4 PF08448.10 AAAP01001890.1_1 - 1.3e-15 57.6 5.9 3e-06 27.5 1.0 3.3 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01001890.1_1 - 3.1e-08 33.8 0.0 0.00045 20.4 0.0 3.9 2 1 2 4 4 4 2 PAS domain PAS_8 PF13188.7 AAAP01001890.1_1 - 1e-07 31.8 0.0 0.0033 17.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AAAP01001890.1_1 - 1.4e-06 28.5 0.0 0.1 12.9 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AAAP01001890.1_1 - 5.8e-06 26.3 0.0 8.7e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 PAS fold DUF374 PF04028.13 AAAP01001890.1_1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) 4HBT PF03061.22 AAAP01001891.1_2 - 0.00016 22.0 0.0 0.0002 21.6 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAAP01001891.1_2 - 0.0036 16.9 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01001891.1_2 - 0.13 12.4 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase Myb_DNA-bind_6 PF13921.6 AAAP01001891.1_3 - 0.084 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cation_efflux PF01545.21 AAAP01001891.1_4 - 1.1e-06 28.6 0.1 1.1e-06 28.5 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4192 PF13830.6 AAAP01001892.1_1 - 2.8e-14 53.9 14.5 5.8e-14 52.9 14.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4192) AMP-binding_C PF13193.6 AAAP01001892.1_1 - 0.04 14.9 0.5 0.1 13.6 0.4 1.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain TPR_14 PF13428.6 AAAP01001892.1_1 - 1.2 10.1 6.9 0.83 10.6 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat CBS PF00571.28 AAAP01001893.1_2 - 1.1e-15 57.8 2.3 1.1e-07 32.2 0.3 2.6 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 AAAP01001893.1_2 - 2.1e-14 53.3 1.4 5e-14 52.1 0.1 2.2 3 0 0 3 3 3 1 Transporter associated domain FCD PF07729.12 AAAP01001894.1_1 - 1.5e-09 38.3 2.3 1.8e-09 38.1 2.3 1.1 1 0 0 1 1 1 1 FCD domain Glyco_transf_4 PF13439.6 AAAP01001894.1_2 - 6.2e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01001894.1_2 - 2.8e-05 24.6 1.1 7.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 AAAP01001894.1_2 - 0.18 11.5 0.1 0.26 11.0 0.1 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain bPH_2 PF03703.14 AAAP01001895.1_1 - 1.7e-21 76.2 0.1 2.4e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain bPH_4 PF06713.11 AAAP01001895.1_1 - 0.023 14.8 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial PH domain bPH_3 PF14470.6 AAAP01001895.1_1 - 0.028 14.8 0.0 0.039 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain MOSC PF03473.17 AAAP01001895.1_2 - 4.2e-09 36.5 0.1 5.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 MOSC domain Pyr_redox_2 PF07992.14 AAAP01001896.1_1 - 4e-18 65.7 0.2 1.1e-17 64.3 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01001896.1_1 - 4.1e-09 36.9 0.4 0.00018 22.0 0.1 3.4 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 AAAP01001896.1_1 - 5e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 AAAP01001896.1_1 - 2.2e-08 34.2 0.1 7e-08 32.6 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AAAP01001896.1_1 - 1.5e-06 27.6 0.1 0.0042 16.4 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAAP01001896.1_1 - 4.1e-06 26.3 0.1 0.011 15.0 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01001896.1_1 - 4.4e-06 26.0 0.3 1.1e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAAP01001896.1_1 - 6.8e-06 25.7 0.0 6.8e-06 25.7 0.0 1.5 2 0 0 2 2 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01001896.1_1 - 1.6e-05 23.8 0.1 1.6e-05 23.8 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 AAAP01001896.1_1 - 2e-05 24.1 0.1 3.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 AAAP01001896.1_1 - 2.1e-05 24.3 1.4 0.0013 18.4 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAAP01001896.1_1 - 3e-05 24.4 0.9 0.061 13.8 0.0 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 AAAP01001896.1_1 - 0.00011 21.6 0.2 0.00019 20.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 AAAP01001896.1_1 - 0.00028 20.3 0.1 0.0019 17.6 0.1 2.1 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAAP01001896.1_1 - 0.00035 20.5 0.0 0.0012 18.8 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 AAAP01001896.1_1 - 0.0011 18.1 0.0 0.0011 18.1 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A AdoHcyase_NAD PF00670.21 AAAP01001896.1_1 - 0.0073 16.4 0.6 3.7 7.6 0.1 2.3 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 AAAP01001896.1_1 - 0.0078 16.8 0.0 0.12 12.9 0.0 2.5 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AAAP01001896.1_1 - 0.0098 16.0 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 AAAP01001896.1_1 - 0.0099 14.3 0.0 1.3 7.3 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 AAAP01001896.1_1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 AAAP01001896.1_1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 AAAP01001896.1_1 - 0.022 13.8 0.1 0.12 11.4 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 AAAP01001896.1_1 - 0.025 13.7 0.0 5.5 6.0 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_2 PF03446.15 AAAP01001896.1_1 - 0.028 14.6 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.6 AAAP01001896.1_1 - 0.06 13.3 0.1 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding IlvN PF07991.12 AAAP01001896.1_1 - 0.079 12.5 1.0 0.12 12.0 0.1 1.7 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MdcE PF06833.11 AAAP01001897.1_1 - 3.6e-55 187.0 0.6 4e-55 186.8 0.6 1.0 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) baeRF_family10 PF18854.1 AAAP01001897.1_2 - 0.073 13.3 0.9 14 5.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 MdcE PF06833.11 AAAP01001897.1_2 - 1.5 8.2 6.1 0.29 10.6 2.7 1.5 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) DUF3445 PF11927.8 AAAP01001898.1_1 - 0.027 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) IlvN PF07991.12 AAAP01001898.1_1 - 0.037 13.6 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fer2 PF00111.27 AAAP01001898.1_2 - 3e-14 52.7 2.4 5.6e-14 51.9 2.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AAAP01001898.1_2 - 0.0003 21.4 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AAAP01001898.1_2 - 0.00057 20.2 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AAAP01001898.1_2 - 0.052 13.7 2.3 0.4 10.8 0.7 2.6 1 1 1 3 3 3 0 Ferric reductase NAD binding domain GNVR PF13807.6 AAAP01001899.1_1 - 1.3e-06 28.2 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase AP_endonuc_2 PF01261.24 AAAP01001899.1_1 - 0.037 13.5 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF5133 PF17196.4 AAAP01001899.1_1 - 0.079 13.2 0.9 0.21 11.8 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) TDA11 PF17084.5 AAAP01001899.1_1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 SRP54 PF00448.22 AAAP01001900.1_1 - 3.8e-68 229.0 1.8 5.6e-68 228.4 1.8 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AAAP01001900.1_1 - 7.7e-20 70.9 0.3 1.8e-19 69.7 0.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AAAP01001900.1_1 - 1.8e-07 31.3 0.0 8.7e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AAAP01001900.1_1 - 5.5e-07 29.1 0.1 1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 AAAP01001900.1_1 - 0.00019 21.6 0.1 0.00044 20.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01001900.1_1 - 0.00091 19.6 0.8 0.002 18.6 0.6 1.7 1 1 1 2 2 2 1 AAA ATPase domain ArsA_ATPase PF02374.15 AAAP01001900.1_1 - 0.0027 16.9 0.2 0.046 12.9 0.1 2.1 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 AAAP01001900.1_1 - 0.0039 17.1 0.0 0.0083 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAAP01001900.1_1 - 0.0046 17.4 0.2 0.013 15.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AAAP01001900.1_1 - 0.012 15.3 0.0 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 AAAP01001900.1_1 - 0.013 16.0 0.1 0.026 14.9 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 AAAP01001900.1_1 - 0.013 14.9 0.2 0.021 14.2 0.2 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain 6PF2K PF01591.18 AAAP01001900.1_1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.20 AAAP01001900.1_1 - 0.017 15.0 0.1 0.068 13.1 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase Arf PF00025.21 AAAP01001900.1_1 - 0.025 14.1 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_5 PF07728.14 AAAP01001900.1_1 - 0.043 13.8 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AAAP01001900.1_1 - 0.05 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01001900.1_1 - 0.053 13.8 0.4 0.11 12.9 0.4 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAAP01001900.1_1 - 0.064 12.2 0.0 0.22 10.4 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 AAAP01001900.1_1 - 0.069 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AAAP01001900.1_1 - 0.077 12.9 0.1 0.33 10.9 0.0 2.1 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 AAAP01001900.1_1 - 0.083 12.6 8.1 0.031 14.0 5.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAAP01001900.1_1 - 0.092 12.8 0.9 1.4 9.1 0.3 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AAAP01001900.1_1 - 0.095 13.0 0.1 0.22 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01001900.1_1 - 0.096 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01001900.1_1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 AAAP01001900.1_1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ExbD PF02472.16 AAAP01001901.1_1 - 1.5e-13 51.0 0.0 1.7e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR Mitofilin PF09731.9 AAAP01001901.1_2 - 2.2 7.0 46.3 2.9 6.6 46.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DNA_pol_B_exo2 PF10108.9 AAAP01001902.1_1 - 6.4e-35 120.8 0.0 7.2e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB AAA_21 PF13304.6 AAAP01001902.1_2 - 0.001 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01001902.1_2 - 0.031 13.7 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain CxxCxxCC PF03692.15 AAAP01001903.1_1 - 2.8e-09 37.5 7.0 5.2e-09 36.7 7.0 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain TadE PF07811.12 AAAP01001903.1_2 - 7.7e-07 29.3 6.4 1.4e-06 28.5 6.4 1.4 1 0 0 1 1 1 1 TadE-like protein Flp_Fap PF04964.14 AAAP01001903.1_2 - 7.2e-05 22.5 1.1 0.00057 19.7 1.1 2.1 1 1 0 1 1 1 1 Flp/Fap pilin component TadF PF16964.5 AAAP01001903.1_2 - 0.0034 17.2 0.1 0.0047 16.7 0.1 1.2 1 0 0 1 1 1 1 Putative tight adherence pilin protein F DUF4244 PF14029.6 AAAP01001903.1_2 - 0.5 9.8 4.6 1.6 8.2 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4244) Hydantoinase_A PF01968.18 AAAP01001904.1_1 - 5.9e-09 35.6 0.0 1.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Carb_kinase PF01256.17 AAAP01001905.1_1 - 1.9e-30 106.1 7.0 2.7e-23 82.7 0.1 2.7 2 1 1 3 3 3 2 Carbohydrate kinase YjeF_N PF03853.15 AAAP01001905.1_1 - 1.2e-05 25.3 1.9 1.5e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 YjeF-related protein N-terminus Mucin PF01456.17 AAAP01001905.1_1 - 0.29 11.1 24.7 0.043 13.8 18.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein FSA_C PF10479.9 AAAP01001905.1_1 - 7 4.7 8.1 9.4 4.2 8.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus rve PF00665.26 AAAP01001906.1_1 - 4.8e-17 62.2 0.1 6.3e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01001906.1_1 - 0.091 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain FHIPEP PF00771.20 AAAP01001907.1_1 - 2.3e-74 251.1 0.0 2.5e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 FHIPEP family UDPG_MGDP_dh PF00984.19 AAAP01001908.1_1 - 7e-18 64.6 0.0 1.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAAP01001908.1_1 - 3.4e-17 62.8 0.0 5.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain CHASE3 PF05227.13 AAAP01001909.1_1 - 2e-40 137.9 2.9 2e-40 137.9 2.9 2.3 2 0 0 2 2 2 1 CHASE3 domain HAMP PF00672.25 AAAP01001909.1_1 - 9.9e-08 32.2 0.4 9.9e-08 32.2 0.4 2.7 3 1 0 3 3 3 1 HAMP domain ATG_C PF09333.11 AAAP01001909.1_1 - 1.1 9.7 8.4 2.5 8.5 1.9 2.6 2 1 1 3 3 3 0 Autophagy-related protein C terminal domain Beta-lactamase PF00144.24 AAAP01001910.1_1 - 1.3e-35 123.2 0.1 1.4e-35 123.1 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Trehalose_PPase PF02358.16 AAAP01001910.1_2 - 1.8e-36 125.5 0.0 2.2e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 AAAP01001910.1_2 - 8e-08 32.3 0.0 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAAP01001910.1_2 - 0.0028 17.2 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase DUF3263 PF11662.8 AAAP01001910.1_2 - 0.12 12.3 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) HAD PF12710.7 AAAP01001910.1_2 - 2.3 8.6 9.1 1.8 8.9 0.1 3.3 2 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase HATPase_c PF02518.26 AAAP01001911.1_1 - 1.6e-16 60.8 0.0 2.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAAP01001911.1_1 - 0.00015 21.5 0.1 0.00051 19.8 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAAP01001911.1_1 - 0.00082 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACR_tran PF00873.19 AAAP01001912.1_1 - 1.4e-35 122.4 12.5 1.6e-35 122.1 12.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Peptidase_S11 PF00768.20 AAAP01001913.1_1 - 2.1e-34 119.0 0.0 2.4e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAAP01001913.1_1 - 1.9e-11 43.9 0.0 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AAAP01001913.1_1 - 5.9e-05 22.0 0.2 0.00051 18.9 0.1 1.9 1 1 1 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AAAP01001913.1_1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.3 1 1 0 1 1 1 0 Beta-lactamase DNA_pol_A_exo1 PF01612.20 AAAP01001913.1_2 - 9.3e-33 113.4 0.0 1.1e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease COX15-CtaA PF02628.15 AAAP01001914.1_1 - 1e-71 241.7 5.4 1.2e-71 241.4 5.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein TPP_enzyme_M PF00205.22 AAAP01001915.1_2 - 0.0072 16.1 0.3 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain E1-N PF14463.6 AAAP01001916.1_2 - 0.023 14.5 1.6 0.025 14.4 1.6 1.2 1 0 0 1 1 1 0 E1 N-terminal domain RskA PF10099.9 AAAP01001917.1_1 - 0.98 9.7 9.1 1.2 9.4 9.1 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Trns_repr_metal PF02583.17 AAAP01001917.1_2 - 3.1e-23 81.9 0.2 3.5e-23 81.8 0.2 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor CheW PF01584.19 AAAP01001917.1_2 - 0.027 14.1 0.0 0.032 13.8 0.0 1.0 1 0 0 1 1 1 0 CheW-like domain Deltameth_res PF16020.5 AAAP01001917.1_3 - 1.9 8.4 3.8 0.41 10.5 0.5 1.5 2 0 0 2 2 2 0 Deltamethrin resistance ABC_tran PF00005.27 AAAP01001918.1_1 - 4.8e-09 36.8 0.1 3.6e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01001918.1_1 - 4.1e-08 33.0 0.1 9.9e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter RrnaAD PF00398.20 AAAP01001918.1_1 - 0.066 12.3 0.1 0.084 11.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ABC_tran PF00005.27 AAAP01001918.1_2 - 1.7e-32 112.8 0.1 2.3e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01001918.1_2 - 1.7e-07 31.4 0.0 0.00079 19.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 AAAP01001918.1_2 - 0.00021 20.7 1.0 0.00048 19.6 0.4 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAAP01001918.1_2 - 0.00026 21.3 0.1 0.0011 19.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01001918.1_2 - 0.0036 17.2 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAAP01001918.1_2 - 0.004 16.9 0.1 0.0073 16.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAAP01001918.1_2 - 0.0071 16.4 0.4 0.0097 16.0 0.4 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01001918.1_2 - 0.009 15.5 0.4 0.15 11.4 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01001918.1_2 - 0.017 15.5 0.1 0.025 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 AAAP01001918.1_2 - 0.033 13.9 0.3 0.1 12.3 0.2 1.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 AAAP01001918.1_2 - 0.036 14.0 0.3 0.068 13.1 0.3 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AAAP01001918.1_2 - 0.045 13.5 1.1 0.067 12.9 1.1 1.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AAAP01001918.1_2 - 0.09 12.8 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Dynamin family NB-ARC PF00931.22 AAAP01001918.1_2 - 0.092 11.9 0.6 0.17 11.0 0.6 1.4 1 0 0 1 1 1 0 NB-ARC domain KH_1 PF00013.29 AAAP01001918.1_2 - 0.093 12.6 1.3 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 KH domain DUF87 PF01935.17 AAAP01001918.1_2 - 0.11 12.6 0.6 0.19 11.8 0.3 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 AAAP01001918.1_2 - 0.11 12.9 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 AAAP01001918.1_2 - 0.15 12.1 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain CDP-OH_P_transf PF01066.21 AAAP01001919.1_1 - 2.3e-08 34.7 1.5 5.3e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UvrC_HhH_N PF08459.11 AAAP01001919.1_2 - 3.2e-52 176.5 0.0 4.1e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 AAAP01001919.1_2 - 3.2e-09 37.3 0.0 6.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 AAAP01001919.1_2 - 1.3e-07 31.6 0.1 2.7e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AAAP01001919.1_2 - 0.00026 20.7 0.0 0.029 14.2 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif PCuAC PF04314.13 AAAP01001920.1_1 - 1.4e-36 124.6 0.0 1.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C LTD PF00932.19 AAAP01001920.1_1 - 0.049 14.0 0.0 0.07 13.5 0.0 1.3 1 0 0 1 1 1 0 Lamin Tail Domain HAMP PF00672.25 AAAP01001921.1_2 - 1.1e-10 41.7 0.0 3.3e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 HAMP domain RibD_C PF01872.17 AAAP01001922.1_1 - 0.00046 20.1 0.0 0.00064 19.6 0.0 1.3 1 1 0 1 1 1 1 RibD C-terminal domain HalOD2 PF18547.1 AAAP01001922.1_1 - 0.015 15.2 0.6 0.063 13.2 0.1 2.1 2 0 0 2 2 2 0 Halobacterial output domain 2 OsmC PF02566.19 AAAP01001922.1_2 - 1.6e-16 60.6 0.2 2.5e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 OsmC-like protein UbiA PF01040.18 AAAP01001923.1_1 - 2.5e-46 158.0 15.5 3.2e-46 157.7 15.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MerR_1 PF13411.6 AAAP01001924.1_2 - 1.6e-08 34.5 0.0 2.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01001924.1_2 - 0.00017 21.3 0.9 0.00075 19.2 0.1 2.2 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AAAP01001924.1_2 - 0.0022 18.5 0.0 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 MerR, DNA binding GerE PF00196.19 AAAP01001924.1_3 - 2.2e-15 55.9 0.1 3.3e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AAAP01001924.1_3 - 6.4e-07 28.8 0.4 2.9e-05 23.5 0.3 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAAP01001924.1_3 - 1e-05 25.1 0.1 2.6e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 AAAP01001924.1_3 - 1.2e-05 25.2 1.8 0.00028 20.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01001924.1_3 - 0.00015 21.4 0.2 0.00049 19.8 0.2 1.9 1 0 0 1 1 1 1 Homeodomain-like domain TPR_2 PF07719.17 AAAP01001924.1_3 - 0.00021 21.1 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat HTH_11 PF08279.12 AAAP01001924.1_3 - 0.00076 19.4 0.3 0.0017 18.3 0.2 1.7 2 0 0 2 2 2 1 HTH domain HTH_30 PF13556.6 AAAP01001924.1_3 - 0.0023 17.7 0.3 0.012 15.4 0.1 2.2 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain TPR_12 PF13424.6 AAAP01001924.1_3 - 0.0042 17.3 0.1 0.013 15.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01001924.1_3 - 0.0047 16.9 0.1 0.013 15.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01001924.1_3 - 0.0074 16.9 0.6 0.0074 16.9 0.6 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01001924.1_3 - 0.0098 16.4 0.5 0.0098 16.4 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat HTH_38 PF13936.6 AAAP01001924.1_3 - 0.014 15.2 0.5 0.09 12.6 0.1 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AAAP01001924.1_3 - 0.021 14.9 0.2 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase TPR_8 PF13181.6 AAAP01001924.1_3 - 0.036 14.3 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01001924.1_3 - 0.066 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01001924.1_3 - 0.14 12.0 0.2 0.14 12.0 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01001924.1_3 - 1 10.3 7.6 0.58 11.1 3.4 2.7 2 1 0 2 2 1 0 Tetratricopeptide repeat Hexapep PF00132.24 AAAP01001925.1_2 - 2.5e-09 36.5 6.0 0.00042 19.9 0.3 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) TAT_signal PF10518.9 AAAP01001926.1_2 - 1.7 8.6 8.7 4.2 7.4 8.7 1.7 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Nitrate_red_del PF02613.15 AAAP01001926.1_3 - 9.5e-30 103.4 0.2 1.4e-29 102.9 0.2 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit Glyco_hydro_65m PF03632.15 AAAP01001927.1_1 - 1.6e-50 172.1 0.0 1.8e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 AAAP01001927.1_1 - 2.2e-09 37.1 0.3 4.2e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Abhydrolase_1 PF00561.20 AAAP01001927.1_2 - 9.3e-12 45.1 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01001927.1_2 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TerB PF05099.13 AAAP01001928.1_1 - 2.6e-07 30.7 0.1 3.8e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TerB Carboxyl_trans PF01039.22 AAAP01001928.1_2 - 2e-73 247.7 0.0 2.4e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAAP01001928.1_2 - 0.022 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) OHCU_decarbox PF09349.10 AAAP01001928.1_2 - 0.082 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 OHCU decarboxylase NUC130_3NT PF08158.12 AAAP01001928.1_2 - 0.084 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 NUC130/3NT domain DUF3408 PF11888.8 AAAP01001928.1_2 - 0.14 12.3 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Trns_repr_metal PF02583.17 AAAP01001929.1_1 - 6e-23 81.0 2.5 7.1e-23 80.8 2.5 1.1 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor DnaG_DnaB_bind PF08278.11 AAAP01001929.1_1 - 0.055 14.1 0.3 0.07 13.7 0.3 1.4 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding T3SS_ATPase_C PF18269.1 AAAP01001929.1_1 - 0.073 12.9 0.2 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain Arg_decarbox_C PF17944.1 AAAP01001929.1_1 - 0.14 12.8 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension DUF326 PF03860.16 AAAP01001929.1_2 - 0.086 12.8 44.4 0.24 11.4 11.0 4.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF326) His_biosynth PF00977.21 AAAP01001930.1_1 - 2e-49 168.1 0.4 2.3e-49 167.9 0.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAAP01001930.1_1 - 5.6e-05 22.4 0.1 0.041 13.0 0.0 2.1 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AAAP01001930.1_1 - 0.0037 16.7 1.3 0.017 14.5 0.2 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase bacHORMA_2 PF18173.1 AAAP01001930.1_1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 His_biosynth PF00977.21 AAAP01001930.1_2 - 9.4e-89 296.8 0.6 1.1e-88 296.6 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 AAAP01001930.1_2 - 3.6e-07 29.9 11.9 0.00017 21.1 6.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.17 AAAP01001930.1_2 - 1.9e-05 24.0 0.0 0.031 13.4 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AAAP01001930.1_2 - 0.00029 20.1 1.1 0.33 10.1 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 AAAP01001930.1_2 - 0.00074 18.9 0.2 0.31 10.4 0.0 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase ThiG PF05690.14 AAAP01001930.1_2 - 0.0025 17.2 10.3 0.14 11.5 0.2 2.4 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 AAAP01001930.1_2 - 0.029 13.8 0.3 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 AAAP01001930.1_2 - 0.092 11.8 10.4 0.42 9.6 0.3 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF5423 PF17461.2 AAAP01001930.1_2 - 0.24 10.2 1.0 0.4 9.5 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Metallophos PF00149.28 AAAP01001931.1_1 - 4.4e-10 40.4 0.0 8.5e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01001931.1_1 - 3.8e-08 33.7 0.0 3.4e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ammonium_transp PF00909.21 AAAP01001932.1_1 - 2.3e-55 187.9 19.2 4.5e-55 187.0 19.2 1.4 1 1 0 1 1 1 1 Ammonium Transporter Family Baculo_p74 PF04583.12 AAAP01001932.1_1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Terminase_1 PF03354.15 AAAP01001933.1_1 - 1.7e-39 135.7 0.0 1.9e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Phage Terminase NAD_binding_2 PF03446.15 AAAP01001934.1_1 - 2.6e-49 167.4 2.3 4.3e-49 166.7 2.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAAP01001934.1_1 - 1.7e-34 118.6 0.2 1.7e-34 118.6 0.2 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAAP01001934.1_1 - 3.8e-09 37.0 0.1 8.8e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAAP01001934.1_1 - 8.9e-07 28.7 0.1 1.4e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAAP01001934.1_1 - 1.3e-05 25.3 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AAAP01001934.1_1 - 3.9e-05 23.6 0.2 7.5e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAAP01001934.1_1 - 0.0004 20.7 0.1 0.0026 18.0 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AAAP01001934.1_1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01001934.1_1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAAP01001934.1_1 - 0.023 14.7 0.2 0.047 13.7 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AAAP01001934.1_1 - 0.1 13.4 0.6 0.18 12.6 0.1 1.6 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold NIR_SIR_ferr PF03460.17 AAAP01001935.1_1 - 6.7e-17 61.1 0.0 1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 AAAP01001935.1_1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain NAD_binding_1 PF00175.21 AAAP01001935.1_2 - 0.00019 22.0 0.0 0.00024 21.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CBM_48 PF02922.18 AAAP01001936.1_1 - 1.4e-06 28.6 0.0 1.5e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF2852 PF11014.8 AAAP01001936.1_2 - 7.2e-20 71.4 4.6 1e-19 70.9 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) DUF5320 PF17253.2 AAAP01001936.1_2 - 0.057 14.5 0.9 0.092 13.8 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) AAA PF00004.29 AAAP01001937.1_1 - 6.2e-43 146.4 0.0 1.2e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 AAAP01001937.1_1 - 1.9e-27 96.4 0.1 2.9e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 AAAP01001937.1_1 - 4.7e-17 61.5 0.3 9.5e-17 60.5 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 AAAP01001937.1_1 - 8.6e-08 32.5 0.4 8.6e-08 32.5 0.4 1.9 2 0 0 2 2 2 1 FtsH Extracellular AAA_16 PF13191.6 AAAP01001937.1_1 - 3.6e-05 24.2 4.6 0.00083 19.8 4.6 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01001937.1_1 - 0.00011 22.5 0.4 0.023 15.0 0.1 2.5 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 AAAP01001937.1_1 - 0.00011 22.0 0.0 0.00045 20.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAAP01001937.1_1 - 0.00011 22.2 0.6 0.00098 19.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAAP01001937.1_1 - 0.00019 20.8 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AAAP01001937.1_1 - 0.00039 20.2 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 AAAP01001937.1_1 - 0.0035 17.5 0.0 0.0064 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01001937.1_1 - 0.0035 16.7 0.8 0.017 14.5 0.2 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 AAAP01001937.1_1 - 0.0036 17.7 0.0 0.0069 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01001937.1_1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01001937.1_1 - 0.026 15.1 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AAAP01001937.1_1 - 0.038 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 AAAP01001937.1_1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 AAAP01001937.1_1 - 0.16 11.3 0.2 0.36 10.1 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 AAAP01001937.1_1 - 0.19 11.5 0.1 0.5 10.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01001937.1_1 - 0.21 11.1 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M50B PF13398.6 AAAP01001937.1_1 - 0.54 9.9 0.0 0.54 9.9 0.0 2.4 3 0 0 3 3 3 0 Peptidase M50B-like DUF1624 PF07786.12 AAAP01001938.1_1 - 3.2e-05 23.6 12.4 9.8e-05 22.0 9.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1624) Acyl_transf_3 PF01757.22 AAAP01001938.1_1 - 0.021 13.9 23.9 0.035 13.2 23.9 1.3 1 0 0 1 1 1 0 Acyltransferase family HTH_31 PF13560.6 AAAP01001939.1_2 - 0.011 16.1 0.4 0.035 14.4 0.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3853 PF12964.7 AAAP01001939.1_2 - 0.013 15.6 0.0 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Glyco_trans_1_2 PF13524.6 AAAP01001939.1_2 - 0.1 13.0 0.1 0.27 11.6 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Acyl-CoA_dh_2 PF08028.11 AAAP01001940.1_1 - 4.4e-10 40.0 13.1 6.3e-10 39.4 13.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAAP01001940.1_1 - 0.39 10.9 7.5 1.1 9.5 7.5 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain PCMT PF01135.19 AAAP01001940.1_2 - 1.3e-19 70.8 0.0 5.8e-19 68.7 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AAAP01001940.1_2 - 9.3e-08 32.7 0.0 1.4e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AAAP01001940.1_2 - 1.4e-06 27.6 0.0 1.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 AAAP01001940.1_2 - 0.00012 22.6 0.0 0.00023 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAAP01001940.1_2 - 0.00035 20.3 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 AAAP01001940.1_2 - 0.00079 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAAP01001940.1_2 - 0.0023 18.1 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 AAAP01001940.1_2 - 0.0042 16.2 0.0 0.0055 15.8 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin Ubie_methyltran PF01209.18 AAAP01001940.1_2 - 0.023 14.0 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AAAP01001940.1_2 - 0.072 13.1 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAAP01001940.1_2 - 0.13 11.9 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain GCD14 PF08704.10 AAAP01001940.1_2 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ABC_tran PF00005.27 AAAP01001942.1_1 - 0.00011 22.7 0.0 0.00015 22.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01001942.1_1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01001942.1_1 - 0.016 15.7 0.1 0.018 15.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01001942.1_1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01001942.1_1 - 0.041 13.8 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AAAP01001942.1_1 - 0.053 13.9 0.0 0.059 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01001942.1_1 - 0.057 13.7 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAAP01001942.1_1 - 0.089 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AAAP01001942.1_1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01001942.1_1 - 0.12 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 AAAP01001942.1_1 - 0.13 11.9 0.4 0.16 11.5 0.4 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 AAAP01001942.1_1 - 0.13 12.1 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 AAAP01001942.1_1 - 0.24 10.4 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 AAAP01001942.1_1 - 0.31 11.6 0.4 0.42 11.2 0.4 1.2 1 0 0 1 1 1 0 AAA domain zinc_ribbon_4 PF13717.6 AAAP01001942.1_2 - 5.4e-13 48.6 0.4 1e-12 47.7 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 AAAP01001942.1_2 - 2.6e-07 30.3 0.2 4.1e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DUF3426 PF11906.8 AAAP01001942.1_2 - 4.4e-06 26.9 0.0 8.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) Zn_Tnp_IS1595 PF12760.7 AAAP01001942.1_2 - 0.073 13.1 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RsmJ PF04378.13 AAAP01001944.1_1 - 1.1e-67 227.8 0.0 1.3e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 AAAP01001944.1_1 - 0.082 12.5 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 CRM1_repeat_2 PF18784.1 AAAP01001944.1_2 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 FAD-oxidase_C PF02913.19 AAAP01001944.1_3 - 2.9e-36 125.4 0.0 3.4e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Transposase_mut PF00872.18 AAAP01001946.1_3 - 2e-06 26.9 0.0 2.5e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family DnaB_bind PF10410.9 AAAP01001946.1_3 - 0.059 13.6 0.1 9.1 6.6 0.0 2.9 3 1 0 3 3 3 0 DnaB-helicase binding domain of primase YjbR PF04237.13 AAAP01001947.1_1 - 3.2e-10 40.4 0.0 4.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 YjbR DUF1923 PF09083.10 AAAP01001947.1_1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) ABC_tran PF00005.27 AAAP01001947.1_2 - 3.4e-32 111.8 0.0 1.9e-19 70.5 0.0 3.1 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 AAAP01001947.1_2 - 4.9e-27 93.8 9.4 3.4e-26 91.1 4.4 2.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 AAAP01001947.1_2 - 3e-08 33.9 1.4 0.05 13.4 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01001947.1_2 - 8e-06 25.5 0.0 0.084 12.3 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01001947.1_2 - 0.029 14.1 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CEP63 PF17045.5 AAAP01001947.1_2 - 0.039 13.8 1.9 0.062 13.2 1.9 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa AAA_16 PF13191.6 AAAP01001947.1_2 - 0.14 12.5 0.1 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AAAP01001947.1_2 - 0.18 12.3 1.9 3.2 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran_CTD PF16326.5 AAAP01001947.1_2 - 3.6 7.9 5.7 0.57 10.5 0.3 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain PHO4 PF01384.20 AAAP01001948.1_2 - 6.3e-34 117.5 1.9 6.4e-34 117.5 1.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family MBOAT PF03062.19 AAAP01001949.1_1 - 0.01 15.2 0.5 0.023 14.0 0.1 1.6 1 1 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family DUF2370 PF10176.9 AAAP01001952.1_2 - 0.068 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) adh_short_C2 PF13561.6 AAAP01001952.1_3 - 1e-45 156.1 0.0 2e-45 155.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01001952.1_3 - 3.5e-44 150.6 0.0 4.9e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01001952.1_3 - 3.9e-05 23.6 0.4 0.00058 19.8 0.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01001952.1_3 - 4.4e-05 23.1 0.4 0.00013 21.5 0.2 1.8 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01001952.1_3 - 6.9e-05 22.8 0.2 0.00011 22.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AdoHcyase_NAD PF00670.21 AAAP01001952.1_3 - 0.00033 20.8 0.1 0.00064 19.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAAP01001952.1_3 - 0.00037 20.8 0.2 0.00064 20.0 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AAAP01001952.1_3 - 0.0021 18.3 0.1 0.0035 17.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 AAAP01001952.1_3 - 0.0076 15.6 0.8 0.013 14.8 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 AAAP01001952.1_3 - 0.079 12.9 0.3 0.19 11.7 0.3 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 AAAP01001952.1_3 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_trans_4_4 PF13579.6 AAAP01001952.1_3 - 0.58 10.6 11.4 0.49 10.8 5.3 2.1 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain DUF962 PF06127.11 AAAP01001953.1_1 - 0.12 12.5 0.0 1.4 9.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Molybdopterin PF00384.22 AAAP01001955.1_1 - 4.9e-10 38.9 0.0 6.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Ribosomal_L35p PF01632.19 AAAP01001956.1_1 - 3.5e-23 81.9 4.7 3.8e-23 81.7 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Glyco_transf_4 PF13439.6 AAAP01001956.1_2 - 8.3e-09 35.7 1.1 1e-08 35.3 1.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01001956.1_2 - 3.6e-06 27.5 0.2 5e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Wzy_C PF04932.15 AAAP01001957.1_1 - 2.9e-16 59.5 0.8 2.9e-16 59.5 0.8 2.7 1 1 2 3 3 3 1 O-Antigen ligase DEAD PF00270.29 AAAP01001958.1_1 - 2.7e-27 95.6 0.0 4.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01001958.1_1 - 8.9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AAAP01001958.1_1 - 0.01 15.4 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01001958.1_1 - 0.04 14.2 0.5 0.33 11.2 0.5 2.3 2 1 0 2 2 2 0 AAA domain Hint_2 PF13403.6 AAAP01001959.1_1 - 1e-12 48.5 0.0 1.5e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Hint domain HWE_HK PF07536.14 AAAP01001960.1_2 - 3.5e-26 91.7 0.2 8.1e-26 90.6 0.2 1.6 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 AAAP01001960.1_2 - 4.5e-12 46.1 0.0 9.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold HisKA_2 PF07568.12 AAAP01001960.1_2 - 3.6e-07 30.2 0.0 7.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase PAS_4 PF08448.10 AAAP01001960.1_2 - 1.1e-05 25.6 0.1 2.6e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01001960.1_2 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAAP01001960.1_2 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 AAAP01001960.1_2 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold Glyco_trans_1_4 PF13692.6 AAAP01001961.1_1 - 1.2e-26 93.7 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01001961.1_1 - 8.6e-22 77.5 0.0 1.3e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01001961.1_1 - 5.1e-10 39.6 0.0 8.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sigma70_r4_2 PF08281.12 AAAP01001961.1_2 - 0.0034 17.0 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01001961.1_2 - 0.0083 15.9 0.1 0.047 13.5 0.0 2.2 2 1 0 2 2 2 1 Homeodomain-like domain AlkA_N PF06029.11 AAAP01001961.1_2 - 0.015 15.5 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 AlkA N-terminal domain DUF4175 PF13779.6 AAAP01001961.1_2 - 0.037 12.0 0.7 0.055 11.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cation_ATPase_N PF00690.26 AAAP01001961.1_2 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus GIDA PF01134.22 AAAP01001962.1_1 - 2.7e-12 46.5 2.3 3e-12 46.4 2.3 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01001962.1_1 - 1.7e-07 31.0 3.0 2e-07 30.8 3.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01001962.1_1 - 6.3e-07 28.8 2.3 6.9e-07 28.7 2.3 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01001962.1_1 - 6.6e-07 28.9 0.7 7.6e-07 28.6 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01001962.1_1 - 1.3e-06 27.9 0.5 1.3e-06 27.9 0.5 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAAP01001962.1_1 - 1.7e-05 25.3 0.6 1.9e-05 25.2 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01001962.1_1 - 0.00076 18.8 0.3 0.0008 18.7 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAAP01001962.1_1 - 0.00083 18.2 0.7 0.0009 18.0 0.7 1.0 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 AAAP01001962.1_1 - 0.00089 18.6 0.0 0.00095 18.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AAAP01001962.1_1 - 0.0015 18.6 0.1 0.0017 18.4 0.1 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AAAP01001962.1_1 - 0.0028 17.0 0.1 0.0029 17.0 0.1 1.0 1 0 0 1 1 1 1 ThiF family Lycopene_cycl PF05834.12 AAAP01001962.1_1 - 0.0031 16.6 0.6 0.0035 16.5 0.6 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 AAAP01001962.1_1 - 0.0042 16.3 0.1 0.0042 16.3 0.1 1.0 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.19 AAAP01001962.1_1 - 0.0064 15.9 0.0 0.007 15.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 AAAP01001962.1_1 - 0.0074 15.9 1.2 0.0079 15.8 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01001962.1_1 - 0.016 15.4 0.9 0.019 15.2 0.9 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 AAAP01001962.1_1 - 0.046 14.2 0.3 0.051 14.1 0.3 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 AAAP01001962.1_1 - 0.054 13.9 0.3 0.056 13.9 0.3 1.0 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 AAAP01001962.1_1 - 0.063 13.2 0.6 0.067 13.1 0.6 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 AAAP01001962.1_1 - 0.13 11.1 0.5 0.14 11.0 0.5 1.0 1 0 0 1 1 1 0 Tryptophan halogenase MnmE_helical PF12631.7 AAAP01001962.1_2 - 4.1e-22 79.4 0.0 4.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 AAAP01001962.1_2 - 0.028 14.5 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 AAAP01001962.1_2 - 0.068 13.2 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Ferredoxin_N PF16947.5 AAAP01001962.1_2 - 0.14 12.3 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Chorismate_bind PF00425.18 AAAP01001963.1_1 - 1.8e-51 175.2 0.0 2e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 chorismate binding enzyme H_PPase PF03030.16 AAAP01001964.1_1 - 1.5e-21 76.7 0.9 1.7e-21 76.5 0.9 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase PTS_EIIC PF02378.18 AAAP01001964.1_1 - 0.0023 17.0 4.3 0.0025 16.9 4.3 1.1 1 0 0 1 1 1 1 Phosphotransferase system, EIIC ATP-synt_I PF03899.15 AAAP01001964.1_1 - 2.4 8.6 13.2 17 5.9 9.6 2.2 1 1 1 2 2 2 0 ATP synthase I chain FeoB_associated PF12669.7 AAAP01001964.1_1 - 2.5 8.5 10.4 39 4.7 0.1 3.2 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DNA_topoisoIV PF00521.20 AAAP01001965.1_1 - 4.5e-86 289.4 0.0 5.5e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DUF2842 PF11003.8 AAAP01001966.1_1 - 3.2e-23 81.8 1.9 3.5e-23 81.6 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2842) DUF5084 PF16894.5 AAAP01001966.1_1 - 0.019 15.4 0.2 0.023 15.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) ABC_membrane PF00664.23 AAAP01001967.1_1 - 3.6e-16 59.6 0.0 6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01001967.1_1 - 2.3e-14 54.1 0.0 6.8e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 AAAP01001967.1_1 - 0.00083 19.0 0.1 0.0042 16.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01001967.1_1 - 0.031 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Methyltransf_2 PF00891.18 AAAP01001967.1_1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MMR_HSR1 PF01926.23 AAAP01001967.1_1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TonB_dep_Rec PF00593.24 AAAP01001968.1_1 - 1.3e-09 38.4 0.7 1.9e-09 38.0 0.7 1.1 1 0 0 1 1 1 1 TonB dependent receptor Big_6 PF17936.1 AAAP01001969.1_1 - 5.2e-05 23.4 0.1 0.00016 21.8 0.1 1.9 1 0 0 1 1 1 1 Bacterial Ig domain Response_reg PF00072.24 AAAP01001970.1_1 - 7.1e-25 87.4 0.1 1.2e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activat PF00158.26 AAAP01001970.1_1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01001970.1_1 - 1.5e-06 28.4 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain LSDAT_euk PF18139.1 AAAP01001970.1_1 - 0.004 16.6 0.2 0.029 13.8 0.1 1.9 2 0 0 2 2 2 1 SLOG in TRPM TadZ_N PF16968.5 AAAP01001970.1_1 - 0.071 12.8 0.6 0.74 9.5 0.0 2.2 1 1 1 2 2 2 0 Pilus assembly protein TadZ N-terminal AAA_7 PF12775.7 AAAP01001970.1_1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 AAAP01001970.1_1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase SecG PF03840.14 AAAP01001971.1_1 - 3.7e-16 58.9 11.1 4.8e-16 58.6 11.1 1.2 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF759 PF05537.11 AAAP01001971.1_1 - 0.084 11.7 0.0 0.098 11.5 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) HNH_5 PF14279.6 AAAP01001972.1_2 - 4.4e-11 42.5 0.2 6.6e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 AAAP01001972.1_2 - 7.9e-09 35.6 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 AAAP01001972.1_2 - 0.00048 20.0 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease DUF1272 PF06906.11 AAAP01001972.1_2 - 0.032 14.3 0.7 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Endonuclease_7 PF02945.15 AAAP01001972.1_2 - 0.046 13.6 0.7 0.095 12.6 0.7 1.5 1 1 0 1 1 1 0 Recombination endonuclease VII Zn_ribbon_SprT PF17283.2 AAAP01001972.1_2 - 0.1 12.5 0.9 0.1 12.5 0.9 1.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain SpoU_methylase PF00588.19 AAAP01001973.1_1 - 7e-25 87.9 0.0 7.4e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family ZnuA PF01297.17 AAAP01001974.1_1 - 1.5e-33 116.3 0.1 1.8e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic IclR PF01614.18 AAAP01001974.1_2 - 0.0016 18.3 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial transcriptional regulator TetR_N PF00440.23 AAAP01001975.1_1 - 1.1e-11 44.3 1.8 3e-11 42.9 0.4 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAAP01001975.1_1 - 3.5e-05 24.0 13.0 3.5e-05 24.0 13.0 2.6 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain DUF981 PF06168.11 AAAP01001975.1_2 - 5.5e-31 107.9 12.1 6.5e-31 107.7 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF981) DUF373 PF04123.13 AAAP01001975.1_2 - 0.031 13.7 1.3 0.044 13.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2583 PF10762.9 AAAP01001975.1_2 - 1 9.8 5.0 2 8.9 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) UCR_Fe-S_N PF10399.9 AAAP01001975.1_2 - 2.5 7.5 7.4 5.4 6.4 0.2 3.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal NDUF_B12 PF08122.12 AAAP01001975.1_2 - 4.1 7.5 5.5 3 7.9 0.1 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family S4 PF01479.25 AAAP01001976.1_1 - 1.2e-12 47.4 0.3 2.9e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 AAAP01001976.1_1 - 2.4e-09 37.5 0.0 3.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase FAA_hydrolase PF01557.18 AAAP01001977.1_2 - 1.5e-61 207.9 0.0 1.6e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CoA_trans PF01144.23 AAAP01001978.1_2 - 1.1e-69 234.2 0.0 1.3e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 AAAP01001978.1_3 - 0.023 14.1 0.0 0.023 14.1 0.0 1.0 1 0 0 1 1 1 0 Coenzyme A transferase ELFV_dehydrog PF00208.21 AAAP01001979.1_1 - 7e-61 206.0 1.1 9.1e-61 205.7 1.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AAAP01001979.1_1 - 4.3e-56 188.4 0.0 6.8e-56 187.7 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 AAAP01001979.1_1 - 0.003 17.0 0.2 0.005 16.2 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_GDH PF05088.12 AAAP01001979.1_1 - 0.024 12.1 0.1 0.033 11.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase 3HCDH_N PF02737.18 AAAP01001979.1_1 - 0.23 11.3 1.2 0.42 10.5 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TarH PF02203.15 AAAP01001980.1_2 - 0.013 15.4 0.3 0.015 15.2 0.3 1.0 1 0 0 1 1 1 0 Tar ligand binding domain homologue CHASE3 PF05227.13 AAAP01001980.1_3 - 0.002 18.0 0.0 0.002 18.0 0.0 1.0 1 0 0 1 1 1 1 CHASE3 domain adh_short PF00106.25 AAAP01001981.1_1 - 1.2e-27 96.7 1.1 3.1e-27 95.3 1.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01001981.1_1 - 1.7e-20 73.6 0.8 3.3e-20 72.6 0.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01001981.1_1 - 9.9e-12 45.1 0.4 1.4e-08 34.9 0.0 2.0 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 AAAP01001981.1_1 - 0.00048 19.7 0.2 0.00053 19.5 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01001981.1_1 - 0.032 13.3 0.1 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Lactamase_B_2 PF12706.7 AAAP01001981.1_1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain RecC_C PF17946.1 AAAP01001981.1_1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 RecC C-terminal domain DUF3099 PF11298.8 AAAP01001981.1_2 - 2.6e-24 85.2 0.9 3.6e-24 84.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) SURF1 PF02104.15 AAAP01001981.1_4 - 2.5e-09 37.6 0.0 3.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SURF1 family DUF3357 PF11837.8 AAAP01001981.1_4 - 0.087 13.3 0.2 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DivIC PF04977.15 AAAP01001981.1_4 - 0.18 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Aconitase PF00330.20 AAAP01001982.1_2 - 4.6e-11 42.4 0.0 5.3e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) BPD_transp_2 PF02653.16 AAAP01001983.1_2 - 5.3e-29 101.2 35.2 5.3e-29 101.2 35.2 1.5 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component DUF1345 PF07077.11 AAAP01001983.1_2 - 0.043 13.5 3.7 0.12 12.0 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF3923 PF13061.6 AAAP01001983.1_2 - 0.067 13.3 0.4 0.067 13.3 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3923) ODV-E18 PF10717.9 AAAP01001983.1_2 - 0.12 12.3 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Ribonuc_L-PSP PF01042.21 AAAP01001984.1_1 - 9.5e-29 99.9 0.2 1e-28 99.8 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP FliH PF02108.16 AAAP01001984.1_1 - 0.025 14.7 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH SBP_bac_8 PF13416.6 AAAP01001984.1_2 - 5e-11 42.9 0.1 5.8e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01001984.1_2 - 4.3e-07 30.2 0.8 5.1e-07 29.9 0.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAAP01001984.1_2 - 0.00016 20.5 0.0 0.0002 20.2 0.0 1.0 1 0 0 1 1 1 1 Hypothetical lipoprotein (MG045 family) SBP_bac_6 PF13343.6 AAAP01001984.1_2 - 0.00053 19.5 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF1232 PF06803.12 AAAP01001984.1_2 - 0.064 13.1 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) SBP_bac_11 PF13531.6 AAAP01001984.1_2 - 0.067 12.9 0.0 0.19 11.4 0.0 1.7 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein Peptidase_M15 PF01427.17 AAAP01001985.1_1 - 1.2e-43 149.2 0.0 1.4e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase VanY PF02557.17 AAAP01001985.1_1 - 0.033 14.0 0.0 0.19 11.5 0.0 2.2 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase CRCB PF02537.15 AAAP01001985.1_2 - 5.1e-12 45.9 4.5 5.6e-12 45.8 4.5 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Ost5 PF05251.12 AAAP01001985.1_2 - 0.093 13.0 5.5 0.11 12.7 5.5 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 rve_3 PF13683.6 AAAP01001986.1_2 - 2.2e-26 91.4 0.0 2.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01001986.1_2 - 0.0013 18.9 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AAAP01001986.1_2 - 0.0024 18.0 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAAP01001986.1_2 - 0.021 15.1 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 DDE domain 2_5_RNA_ligase2 PF13563.6 AAAP01001986.1_2 - 0.062 13.2 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily PALP PF00291.25 AAAP01001987.1_1 - 1.7e-50 172.1 3.4 2.1e-50 171.8 3.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AI-2E_transport PF01594.16 AAAP01001987.1_2 - 8.3e-41 140.2 26.7 1e-40 139.9 26.7 1.0 1 0 0 1 1 1 1 AI-2E family transporter GerA PF03323.13 AAAP01001988.1_1 - 0.071 11.6 0.0 0.078 11.4 0.0 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Metallophos PF00149.28 AAAP01001988.1_2 - 1.3e-10 42.1 0.0 1.5e-10 42.0 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01001988.1_2 - 0.0044 17.2 0.1 0.0062 16.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain baeRF_family2 PF18844.1 AAAP01001988.1_2 - 0.045 13.8 1.3 0.067 13.2 1.3 1.6 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 GntR PF00392.21 AAAP01001989.1_1 - 2.5e-14 52.7 0.0 8.9e-14 50.9 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 AAAP01001989.1_1 - 1.6e-11 44.0 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_Crp_2 PF13545.6 AAAP01001989.1_1 - 0.00099 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAAP01001989.1_1 - 0.0025 17.3 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAAP01001989.1_1 - 0.0042 16.9 0.1 0.022 14.7 0.2 2.1 2 0 0 2 2 2 1 MarR family HTH_36 PF13730.6 AAAP01001989.1_1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AAAP01001989.1_1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain CSD PF00313.22 AAAP01001990.1_2 - 2.3e-31 107.4 0.0 2.1e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01001990.1_2 - 8.5e-07 28.6 0.1 0.067 12.9 0.0 2.6 3 0 0 3 3 3 2 Ribonuclease B OB domain Baculo_E56 PF04639.12 AAAP01001990.1_2 - 0.14 11.4 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF192 PF02643.15 AAAP01001990.1_3 - 2.3e-11 43.7 0.5 3e-11 43.3 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 NADHdh PF00146.21 AAAP01001992.1_1 - 6.2e-51 173.5 14.6 6.9e-51 173.3 14.6 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.27 AAAP01001992.1_2 - 2.4e-13 49.3 18.5 1.1e-07 31.4 5.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01001992.1_2 - 1.2e-12 48.2 10.9 2e-12 47.5 10.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01001992.1_2 - 1.1e-10 42.3 5.0 2.1e-05 25.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01001992.1_2 - 1.1e-09 38.3 4.2 0.00016 21.8 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01001992.1_2 - 2e-09 37.5 10.5 3.6e-09 36.7 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01001992.1_2 - 1.6e-08 34.5 22.5 3.1e-06 27.2 13.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01001992.1_2 - 3.6e-07 30.5 19.8 8.5e-05 22.9 11.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01001992.1_2 - 6.2e-07 29.2 18.9 0.00033 20.6 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01001992.1_2 - 2.9e-06 27.0 11.9 0.0092 16.0 2.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01001992.1_2 - 4.4e-06 26.8 10.8 0.00024 21.3 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01001992.1_2 - 0.00015 22.2 11.9 0.02 15.4 13.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01001992.1_2 - 0.0075 16.8 14.5 0.33 11.5 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 AAAP01001992.1_2 - 0.015 15.5 5.3 0.64 10.3 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 AAAP01001992.1_2 - 0.033 14.4 9.5 4.4 7.5 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01001992.1_2 - 0.071 14.1 17.5 0.18 12.8 5.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_S26e PF01283.19 AAAP01001992.1_2 - 0.12 12.8 1.0 2.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S26e ETF_QO PF05187.13 AAAP01001992.1_2 - 0.87 9.8 7.9 1.9 8.7 1.0 2.4 2 1 1 3 3 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 AAAP01001992.1_2 - 0.95 10.3 12.6 2.2 9.2 2.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain FAD-oxidase_C PF02913.19 AAAP01001993.1_1 - 1.6e-52 178.6 0.2 2.1e-52 178.3 0.2 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Methyltransf_11 PF08241.12 AAAP01001993.1_1 - 0.074 13.7 0.0 14 6.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MCD PF05292.11 AAAP01001994.1_1 - 2.6e-30 105.9 0.0 3.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain B12-binding PF02310.19 AAAP01001995.1_1 - 1.8e-08 34.5 0.0 2.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 AAAP01001995.1_1 - 0.0033 17.8 1.4 0.0049 17.3 0.6 1.7 2 0 0 2 2 2 1 Radical SAM superfamily DUF364 PF04016.12 AAAP01001995.1_1 - 0.058 13.0 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative heavy-metal chelation FliM PF02154.15 AAAP01001996.1_1 - 2.4e-26 92.8 0.0 3e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Flagellar motor switch protein FliM MotA_ExbB PF01618.16 AAAP01001996.1_2 - 1e-12 47.9 0.2 1.4e-12 47.4 0.2 1.1 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family PspA_IM30 PF04012.12 AAAP01001997.1_2 - 0.0022 17.6 4.6 0.026 14.1 0.8 2.1 2 0 0 2 2 2 2 PspA/IM30 family Pam16 PF03656.13 AAAP01001997.1_2 - 0.038 14.0 0.5 0.097 12.7 0.2 1.8 1 1 1 2 2 2 0 Pam16 TcdA_TcdB_pore PF12920.7 AAAP01001997.1_2 - 0.12 10.6 0.3 0.14 10.3 0.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain ABATE PF07336.11 AAAP01001997.1_2 - 0.45 11.2 7.3 0.049 14.3 2.2 1.9 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Tim44 PF04280.15 AAAP01001998.1_1 - 1.2e-41 142.3 0.1 1.5e-41 141.9 0.1 1.2 1 0 0 1 1 1 1 Tim44-like domain MFS_1 PF07690.16 AAAP01001999.1_1 - 4.8e-32 111.2 26.6 6.2e-32 110.9 26.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 AAAP01001999.1_1 - 2.7e-07 29.4 7.5 3.6e-07 29.0 7.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 AAAP01001999.1_1 - 1.1e-06 27.8 14.7 1e-05 24.6 15.2 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter FAA_hydrolase PF01557.18 AAAP01002000.1_1 - 2.3e-23 83.0 0.0 2.7e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Radical_SAM PF04055.21 AAAP01002000.1_2 - 3.2e-11 43.9 0.0 4.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Abhydrolase_1 PF00561.20 AAAP01002002.1_1 - 4.5e-08 33.0 0.5 5e-08 32.9 0.5 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01002002.1_1 - 1.2e-07 31.2 1.3 1.4e-07 31.0 1.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAAP01002002.1_1 - 1.6e-06 28.9 3.6 1.9e-06 28.7 3.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAAP01002002.1_1 - 0.022 14.4 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) EHN PF06441.12 AAAP01002002.1_1 - 0.031 14.6 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus AXE1 PF05448.12 AAAP01002002.1_1 - 0.032 12.9 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyoxalase_6 PF18029.1 AAAP01002003.1_1 - 1.9e-20 73.6 10.4 7.8e-10 39.5 2.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 AAAP01002003.1_1 - 1.6e-10 41.3 0.0 0.00061 20.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAAP01002003.1_1 - 1.2e-07 31.9 0.3 0.025 14.8 0.0 3.3 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SplA PF11132.8 AAAP01002003.1_2 - 0.071 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) Penicil_amidase PF01804.18 AAAP01002004.1_2 - 9.6e-39 133.9 2.1 1.1e-38 133.8 2.1 1.0 1 0 0 1 1 1 1 Penicillin amidase Filament PF00038.21 AAAP01002005.1_2 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein Penicil_amidase PF01804.18 AAAP01002006.1_1 - 4.4e-50 171.4 2.3 5.2e-50 171.1 2.3 1.0 1 0 0 1 1 1 1 Penicillin amidase DUF3357 PF11837.8 AAAP01002006.1_1 - 0.052 14.0 0.4 0.092 13.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RskA PF10099.9 AAAP01002006.1_1 - 0.27 11.5 10.3 0.37 11.1 10.3 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FXR_C1 PF16096.5 AAAP01002006.1_1 - 0.33 11.2 1.5 0.57 10.4 1.5 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 rve PF00665.26 AAAP01002007.1_1 - 0.00017 21.8 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 AAAP01002007.1_1 - 0.0042 17.2 1.8 0.015 15.4 1.8 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01002007.1_1 - 0.081 12.9 3.8 0.1 12.7 1.2 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HATPase_c PF02518.26 AAAP01002009.1_2 - 8.3e-05 23.1 0.0 0.0001 22.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_38 PF13936.6 AAAP01002010.1_1 - 1.3e-08 34.5 0.2 1.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01002010.1_1 - 4.7e-06 26.2 8.8 0.00079 19.2 1.5 3.4 3 1 0 3 3 3 2 Homeodomain-like domain GerE PF00196.19 AAAP01002010.1_1 - 0.00015 21.2 0.1 0.29 10.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 AAAP01002010.1_1 - 0.0002 21.4 12.8 0.0099 16.0 0.6 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAAP01002010.1_1 - 0.009 15.7 1.3 0.32 10.7 0.3 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_40 PF14493.6 AAAP01002010.1_1 - 0.2 12.1 0.0 3.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01002010.1_1 - 0.23 11.5 8.7 2.8 8.0 0.6 3.0 2 2 0 2 2 2 0 Winged helix-turn helix PPK2 PF03976.14 AAAP01002011.1_1 - 3.9e-36 124.7 0.0 5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) BASP1 PF05466.12 AAAP01002011.1_1 - 1.8 8.5 9.7 0.5 10.3 6.8 1.5 1 1 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Plug PF07715.15 AAAP01002012.1_1 - 1.4e-29 102.8 2.4 2.3e-29 102.1 2.4 1.4 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Semialdhyde_dh PF01118.24 AAAP01002013.1_1 - 2.2e-29 102.3 0.1 3.2e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AAAP01002013.1_1 - 1.2e-13 51.6 0.0 1.8e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain S4 PF01479.25 AAAP01002013.1_1 - 0.0047 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain NmrA PF05368.13 AAAP01002013.1_1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family ACT PF01842.25 AAAP01002013.1_2 - 2.1e-20 72.2 1.4 5.3e-10 38.9 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 AAAP01002013.1_2 - 1.2e-17 63.5 0.4 4.2e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain AA_kinase PF00696.28 AAAP01002013.1_2 - 3.2e-15 56.4 0.0 6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_6 PF13740.6 AAAP01002013.1_2 - 2.7e-05 24.1 0.1 0.028 14.4 0.0 2.4 2 0 0 2 2 2 2 ACT domain AcylCoA_DH_N PF12418.8 AAAP01002014.1_1 - 7.1e-12 45.1 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal SAND PF01342.21 AAAP01002014.1_1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 1 1 2 2 2 0 SAND domain DnaG_DnaB_bind PF08278.11 AAAP01002014.1_2 - 0.02 15.5 0.9 0.67 10.6 0.1 2.5 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding PBP1_TM PF14812.6 AAAP01002014.1_2 - 0.3 11.5 2.6 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_DNAp_acc PF04929.12 AAAP01002014.1_2 - 9.1 5.1 8.1 17 4.2 8.1 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PepX_C PF08530.10 AAAP01002015.1_3 - 0.0027 17.7 0.0 0.0027 17.7 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain SpoIIE PF07228.12 AAAP01002016.1_1 - 2e-43 148.6 4.1 2.7e-43 148.1 4.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DraK_HK_N PF18092.1 AAAP01002016.1_1 - 0.061 13.7 0.5 0.82 10.1 0.0 2.5 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain RibD_C PF01872.17 AAAP01002016.1_2 - 1.6e-19 70.6 0.0 6e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 RibD C-terminal domain NodA PF02474.15 AAAP01002016.1_2 - 0.083 12.6 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein A (NodA) Lyase_1 PF00206.20 AAAP01002017.1_2 - 6.3e-53 180.2 0.0 8.7e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AAAP01002017.1_2 - 5.6e-13 49.1 0.1 1.2e-12 48.0 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ParD PF09386.10 AAAP01002017.1_2 - 0.19 12.1 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 Antitoxin ParD TetR_C_27 PF17935.1 AAAP01002018.1_1 - 4.4e-17 62.1 0.5 7.3e-17 61.4 0.5 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 AAAP01002018.1_1 - 0.0011 19.2 0.3 0.0024 18.1 0.3 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Hyd_WA PF06462.12 AAAP01002019.1_1 - 0.074 13.1 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Propeller 2-oxoacid_dh PF00198.23 AAAP01002019.1_2 - 3.4e-65 219.7 0.0 3.9e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) ParBc PF02195.18 AAAP01002021.1_1 - 1.4e-07 31.7 0.8 4.4e-07 30.1 0.8 1.9 1 0 0 1 1 1 1 ParB-like nuclease domain Pep_deformylase PF01327.21 AAAP01002022.1_1 - 6.1e-30 103.9 0.0 7.6e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Herpes_US12 PF05363.12 AAAP01002022.1_2 - 0.22 12.2 1.4 2.9 8.7 0.1 2.4 2 1 0 2 2 2 0 Herpesvirus US12 family TonB_dep_Rec PF00593.24 AAAP01002022.1_3 - 2.6e-11 44.1 0.7 2.8e-11 44.0 0.7 1.0 1 0 0 1 1 1 1 TonB dependent receptor Exo_endo_phos PF03372.23 AAAP01002023.1_1 - 1.6e-15 57.3 2.1 1.8e-15 57.1 2.1 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_IclR PF09339.10 AAAP01002023.1_2 - 8.4e-05 22.3 1.5 0.0001 22.0 0.3 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAAP01002023.1_2 - 0.006 16.4 0.6 0.006 16.4 0.6 2.1 3 0 0 3 3 3 1 MarR family HTH_29 PF13551.6 AAAP01002023.1_2 - 0.029 14.4 4.8 0.095 12.7 0.7 2.4 1 1 0 2 2 2 0 Winged helix-turn helix FaeA PF04703.12 AAAP01002023.1_2 - 0.038 14.4 0.1 0.073 13.4 0.1 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_11 PF08279.12 AAAP01002023.1_2 - 0.041 13.8 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain FeoC PF09012.10 AAAP01002023.1_2 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator CitT PF12431.8 AAAP01002023.1_2 - 0.24 11.8 2.3 1.2 9.5 2.3 2.1 1 1 0 1 1 1 0 Transcriptional regulator MerR PF00376.23 AAAP01002023.1_2 - 0.53 10.1 4.1 9 6.2 0.1 3.2 3 0 0 3 3 3 0 MerR family regulatory protein Fructosamin_kin PF03881.14 AAAP01002024.1_1 - 1.2e-30 106.8 0.0 1.4e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 AAAP01002024.1_1 - 6.2e-13 49.2 1.2 8.6e-13 48.8 1.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 AAAP01002024.1_1 - 0.0087 15.5 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase NIR_SIR PF01077.22 AAAP01002025.1_1 - 4.1e-31 107.7 0.0 3.6e-23 81.8 0.1 2.1 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01002025.1_1 - 2.5e-15 56.1 0.1 5.7e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain DUF4388 PF14332.6 AAAP01002025.1_1 - 0.084 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) Phage_integrase PF00589.22 AAAP01002026.1_1 - 5.7e-15 55.5 0.1 6.7e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Phage integrase family Sigma70_r4_2 PF08281.12 AAAP01002026.1_1 - 0.095 12.4 0.3 5.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HATPase_c PF02518.26 AAAP01002027.1_1 - 3.7e-14 53.2 0.0 5.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01002027.1_1 - 5.3e-06 26.3 0.0 8.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01002027.1_1 - 0.00021 21.3 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 AAAP01002027.1_2 - 5.5e-21 74.8 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Glyco_trans_4_2 PF13477.6 AAAP01002027.1_2 - 0.0056 16.7 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like OKR_DC_1_N PF03709.15 AAAP01002027.1_2 - 0.04 14.2 0.0 0.086 13.1 0.0 1.5 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain MFS_1 PF07690.16 AAAP01002028.1_1 - 1.5e-39 135.9 20.3 1.7e-39 135.7 20.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01002028.1_1 - 1.1e-08 34.3 6.5 1.4e-08 34.0 6.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 AAAP01002028.1_1 - 2.9e-06 26.0 10.9 3.8e-06 25.6 10.9 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 AAAP01002028.1_1 - 2.2e-05 23.0 2.7 0.014 13.7 0.6 2.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 AAAP01002028.1_1 - 0.0001 21.7 11.1 0.00042 19.7 11.0 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAAP01002028.1_1 - 0.0042 16.0 7.1 0.0053 15.7 7.1 1.1 1 0 0 1 1 1 1 MFS_1 like family PUCC PF03209.15 AAAP01002028.1_1 - 0.0091 15.0 11.3 0.0091 15.0 11.3 1.9 1 1 1 2 2 2 1 PUCC protein TRI12 PF06609.13 AAAP01002028.1_1 - 0.011 14.2 2.1 0.013 14.0 2.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 AAAP01002028.1_1 - 0.035 12.9 0.1 0.084 11.7 0.0 1.6 1 1 0 1 1 1 0 POT family PadR PF03551.14 AAAP01002028.1_2 - 1.2e-13 50.8 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 AAAP01002028.1_2 - 0.014 16.1 0.9 0.029 15.1 0.2 1.9 2 0 0 2 2 2 0 Virulence activator alpha C-term MarR PF01047.22 AAAP01002028.1_2 - 0.017 15.0 0.0 0.051 13.5 0.0 1.9 1 1 0 1 1 1 0 MarR family MarR_2 PF12802.7 AAAP01002028.1_2 - 0.018 14.9 1.0 0.22 11.4 1.0 2.7 1 1 0 1 1 1 0 MarR family HTH_27 PF13463.6 AAAP01002028.1_2 - 0.021 15.3 0.1 0.058 13.9 0.1 1.8 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.6 AAAP01002028.1_2 - 0.063 13.5 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DinB_2 PF12867.7 AAAP01002028.1_2 - 0.081 13.4 4.8 0.13 12.8 4.7 1.6 1 1 0 1 1 1 0 DinB superfamily HTH_24 PF13412.6 AAAP01002028.1_2 - 0.087 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Replic_Relax PF13814.6 AAAP01002028.1_2 - 0.087 12.9 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Replication-relaxation adh_short_C2 PF13561.6 AAAP01002029.1_1 - 5.4e-46 157.1 0.0 6e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002029.1_1 - 8e-34 116.8 0.0 9.4e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 AAAP01002029.1_1 - 0.087 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 AAAP01002029.1_2 - 2.2e-18 66.4 0.1 2.4e-18 66.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002029.1_2 - 2.8e-13 50.0 0.7 3.4e-13 49.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01002029.1_2 - 7.6e-06 26.0 0.1 9.3e-06 25.7 0.1 1.0 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 AAAP01002029.1_2 - 0.0023 17.3 0.1 0.0024 17.3 0.1 1.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AAAP01002029.1_2 - 0.0031 16.8 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 AAAP01002029.1_2 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 AAAP01002029.1_2 - 0.02 14.7 0.4 0.025 14.3 0.4 1.2 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 AAAP01002029.1_2 - 0.023 14.6 1.3 0.032 14.1 1.3 1.2 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 AAAP01002029.1_2 - 0.034 13.8 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.6 AAAP01002029.1_2 - 0.22 12.0 2.5 0.83 10.2 2.5 1.7 1 1 0 1 1 1 0 CoA binding domain DUF4440 PF14534.6 AAAP01002030.1_1 - 2.7e-06 27.7 0.1 3.4e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AAAP01002030.1_1 - 0.012 15.9 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain Transposase_mut PF00872.18 AAAP01002030.1_2 - 6e-19 68.1 0.0 7.8e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.6 AAAP01002030.1_2 - 0.082 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 DDE domain YbhQ PF11076.8 AAAP01002031.1_1 - 0.05 13.6 1.2 0.084 12.9 0.5 1.8 1 1 0 1 1 1 0 Putative inner membrane protein YbhQ CPP1-like PF11833.8 AAAP01002031.1_1 - 2.6 7.7 6.5 5.6 6.6 6.2 1.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like adh_short_C2 PF13561.6 AAAP01002032.1_1 - 7.7e-50 169.6 8.5 5.5e-49 166.8 5.8 2.5 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002032.1_1 - 8.2e-41 139.6 1.0 1e-38 132.8 1.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 AAAP01002032.1_1 - 2.1e-18 66.9 1.9 3.9e-18 66.0 1.9 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01002032.1_1 - 1.6e-05 24.5 0.6 2.4e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CHASE2 PF05226.11 AAAP01002032.1_1 - 0.01 15.6 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 0 CHASE2 domain 3HCDH_N PF02737.18 AAAP01002032.1_1 - 0.2 11.5 1.0 0.31 10.9 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF563 PF04577.14 AAAP01002033.1_1 - 2e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) CmcI PF04989.12 AAAP01002033.1_2 - 0.00064 19.5 0.0 0.00077 19.2 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 AAAP01002033.1_2 - 0.025 15.6 0.1 0.039 15.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 AAAP01002033.1_2 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain tRNA-synt_1 PF00133.22 AAAP01002034.1_1 - 2.9e-28 98.5 0.4 9.3e-27 93.5 0.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01002034.1_1 - 1e-20 73.9 0.0 1.5e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 AAAP01002034.1_1 - 0.00038 19.5 0.0 0.001 18.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AAAP01002034.1_1 - 0.04 13.3 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 AAAP01002034.1_1 - 0.075 12.0 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) Peptidase_M22 PF00814.25 AAAP01002035.1_1 - 7.3e-19 68.5 1.1 1.1e-18 67.9 1.1 1.2 1 0 0 1 1 1 1 Glycoprotease family Acetyltransf_1 PF00583.25 AAAP01002035.1_1 - 3.9e-09 36.8 0.1 6.1e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAAP01002035.1_1 - 8.5e-06 25.7 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01002035.1_1 - 1.9e-05 25.0 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01002035.1_1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 AAAP01002035.1_1 - 0.023 14.4 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01002035.1_1 - 0.058 14.1 0.0 0.086 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SQS_PSY PF00494.19 AAAP01002036.1_1 - 0.027 14.0 0.0 0.027 14.0 0.0 1.0 1 0 0 1 1 1 0 Squalene/phytoene synthase SQS_PSY PF00494.19 AAAP01002036.1_2 - 5.1e-26 91.7 0.0 6.3e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase DDE_3 PF13358.6 AAAP01002037.1_1 - 9.9e-29 100.0 0.0 1.3e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 AAAP01002037.1_1 - 0.026 13.5 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain GST_N_2 PF13409.6 AAAP01002037.1_1 - 0.12 12.7 0.0 7.6 6.9 0.0 2.3 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain rve PF00665.26 AAAP01002037.1_1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Porin_2 PF02530.14 AAAP01002037.1_2 - 1.3e-09 37.8 0.2 1.8e-09 37.4 0.2 1.1 1 0 0 1 1 1 1 Porin subfamily ABC_tran PF00005.27 AAAP01002038.1_1 - 0.00028 21.4 0.0 0.00043 20.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01002038.1_1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01002038.1_1 - 0.0049 16.8 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01002038.1_1 - 0.0055 17.1 0.1 0.012 16.0 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AAAP01002038.1_1 - 0.0058 16.2 0.0 0.012 15.2 0.0 1.6 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.20 AAAP01002038.1_1 - 0.033 14.1 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 AAAP01002038.1_1 - 0.085 13.0 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAAP01002038.1_1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain HemolysinCabind PF00353.19 AAAP01002039.1_1 - 8.1e-13 48.1 74.8 2.7e-05 24.0 3.8 6.0 5 1 0 5 5 5 4 RTX calcium-binding nonapeptide repeat (4 copies) Radical_SAM PF04055.21 AAAP01002040.1_1 - 8.2e-15 55.6 0.2 1.3e-14 54.9 0.2 1.3 1 0 0 1 1 1 1 Radical SAM superfamily PHB_depo_C PF06850.11 AAAP01002041.1_1 - 6.8e-35 120.4 0.0 7.4e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 PHB de-polymerase C-terminus DUF45 PF01863.17 AAAP01002041.1_2 - 7.9e-10 39.1 0.0 9.1e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF45 LprI PF07007.12 AAAP01002043.1_1 - 0.081 13.6 0.1 0.14 12.9 0.1 1.4 1 0 0 1 1 1 0 Lysozyme inhibitor LprI Molybdopterin PF00384.22 AAAP01002043.1_2 - 0.006 15.6 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase DUF2990 PF11693.8 AAAP01002044.1_1 - 0.075 13.2 1.1 2.8 8.2 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2990) Ribosomal_S6 PF01250.17 AAAP01002045.1_1 - 4.9e-27 94.0 0.0 5.4e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 SSB PF00436.25 AAAP01002045.1_2 - 2.5e-22 78.9 0.0 3.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AAAP01002045.1_2 - 0.014 15.3 0.0 0.043 13.8 0.0 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 AAAP01002045.1_2 - 0.027 14.7 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GH43_C2 PF17851.1 AAAP01002046.1_1 - 9.5e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1349 PF07081.11 AAAP01002046.1_1 - 6.9e-10 38.9 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Glyco_hydro_43 PF04616.14 AAAP01002046.1_1 - 0.044 13.1 0.5 4.5 6.5 0.0 2.5 2 1 0 2 2 2 0 Glycosyl hydrolases family 43 Glyco_hydro_130 PF04041.13 AAAP01002046.1_1 - 0.13 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase DUF3693 PF12472.8 AAAP01002047.1_1 - 0.14 11.9 0.4 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Phage related protein bPH_1 PF08000.11 AAAP01002047.1_2 - 1.6e-41 141.2 0.0 2e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 AAAP01002047.1_2 - 0.00019 21.7 0.0 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain Glyco_trans_4_2 PF13477.6 AAAP01002048.1_2 - 3.4e-15 56.3 0.0 5.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_4 PF13692.6 AAAP01002048.1_2 - 1.6e-11 44.7 0.5 2.7e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01002048.1_2 - 0.00012 22.2 0.1 0.00023 21.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01002048.1_2 - 0.00013 21.6 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DNA_topoisoIV PF00521.20 AAAP01002049.1_1 - 1.6e-37 129.4 0.0 2e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAAP01002049.1_1 - 9.6e-26 89.0 0.0 2.8e-14 52.3 0.1 3.5 3 0 0 3 3 3 3 DNA gyrase C-terminal domain, beta-propeller ABC_tran PF00005.27 AAAP01002050.1_1 - 2.2e-09 38.0 0.0 3.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002050.1_1 - 0.0016 18.3 0.1 0.0017 18.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Putative_PNPOx PF01243.20 AAAP01002050.1_2 - 1e-14 54.5 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F420H2_quin_red PF04075.14 AAAP01002050.1_2 - 0.0035 17.5 0.1 0.0043 17.2 0.1 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase CoA_binding_2 PF13380.6 AAAP01002050.1_3 - 9.4e-38 129.3 0.6 1.2e-37 129.0 0.6 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AAAP01002050.1_3 - 0.00056 20.5 0.1 0.00095 19.8 0.1 1.3 1 0 0 1 1 1 1 CoA binding domain Toprim_3 PF13362.6 AAAP01002051.1_2 - 1.6e-24 86.1 0.1 2.7e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAAP01002051.1_2 - 0.021 15.2 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Toprim-like DUF892 PF05974.12 AAAP01002052.1_1 - 4e-57 192.7 8.8 4.4e-57 192.6 8.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) DUF2383 PF09537.10 AAAP01002052.1_1 - 0.0004 20.7 0.7 0.0004 20.7 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) DUF1266 PF06889.11 AAAP01002052.1_1 - 0.0081 16.2 1.6 0.0098 16.0 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1266) Spore_III_AB PF09548.10 AAAP01002052.1_1 - 0.016 15.3 4.0 0.024 14.8 2.9 1.6 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RPT PF13446.6 AAAP01002052.1_1 - 0.046 13.7 0.2 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF4404 PF14357.6 AAAP01002052.1_1 - 6.3 7.5 9.1 1.9 9.2 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DEDD_Tnp_IS110 PF01548.17 AAAP01002052.1_2 - 0.023 14.6 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Transposase ACR_tran PF00873.19 AAAP01002054.1_1 - 4.1e-79 266.5 0.0 4.6e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ACR_tran PF00873.19 AAAP01002054.1_2 - 2.8e-47 161.1 4.7 3.3e-47 160.8 4.7 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family TraL PF07178.11 AAAP01002054.1_2 - 0.65 10.5 3.9 3.4 8.2 0.1 2.2 2 0 0 2 2 2 0 TraL protein Sigma70_r3 PF04539.16 AAAP01002055.1_1 - 1.3e-30 105.3 2.7 5.9e-30 103.2 0.6 2.8 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 AAAP01002055.1_1 - 3.6e-22 77.9 1.2 6.5e-22 77.1 0.3 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAAP01002055.1_1 - 2e-21 75.2 3.8 5.9e-19 67.3 1.1 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_15 PF12324.8 AAAP01002055.1_1 - 0.069 13.1 0.5 0.55 10.2 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase MarR_2 PF12802.7 AAAP01002055.1_1 - 0.087 12.7 0.1 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 MarR family FTCD_C PF04961.12 AAAP01002055.1_1 - 0.1 12.3 0.0 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase HTH_25 PF13413.6 AAAP01002055.1_1 - 0.35 10.7 6.3 6.7 6.7 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain DUF2798 PF11391.8 AAAP01002055.1_2 - 6.3e-20 71.0 9.6 8.2e-20 70.6 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2798) DUF4750 PF15938.5 AAAP01002055.1_2 - 0.021 14.5 0.8 0.021 14.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) ChapFlgA PF13144.6 AAAP01002056.1_2 - 2.6e-20 72.7 0.0 3.2e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation SAF PF08666.12 AAAP01002056.1_2 - 0.0093 16.6 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 SAF domain DUF1421 PF07223.11 AAAP01002056.1_2 - 0.027 14.3 0.1 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) FlgI PF02119.16 AAAP01002056.1_3 - 5e-118 394.0 1.8 6.2e-118 393.7 1.8 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein AA_kinase PF00696.28 AAAP01002057.1_1 - 6.9e-45 153.5 1.0 7.9e-45 153.3 1.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family ArgJ PF01960.18 AAAP01002057.1_2 - 3.4e-06 26.1 0.4 3.4e-06 26.1 0.4 1.0 1 0 0 1 1 1 1 ArgJ family DUF463 PF04317.12 AAAP01002058.1_1 - 1.6e-143 478.8 0.0 1.8e-143 478.7 0.0 1.0 1 0 0 1 1 1 1 YcjX-like family, DUF463 Response_reg PF00072.24 AAAP01002058.1_2 - 3.8e-19 68.9 0.1 4.4e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Abhydrolase_1 PF00561.20 AAAP01002059.1_1 - 0.16 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold MetW PF07021.12 AAAP01002059.1_2 - 1.1e-84 282.9 0.0 1.2e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 AAAP01002059.1_2 - 4.7e-11 42.8 0.0 6e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002059.1_2 - 3.2e-09 37.3 0.0 5.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002059.1_2 - 2e-08 34.2 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002059.1_2 - 2.4e-07 31.4 0.0 4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002059.1_2 - 2.6e-06 28.1 0.1 5.6e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01002059.1_2 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 AAAP01002059.1_2 - 0.005 15.4 0.0 0.0068 15.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HU-CCDC81_euk_2 PF18289.1 AAAP01002059.1_2 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 PCMT PF01135.19 AAAP01002059.1_2 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CusF_Ec PF11604.8 AAAP01002060.1_2 - 1.7e-28 98.3 0.8 2.4e-28 97.9 0.8 1.2 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF PCB_OB PF17092.5 AAAP01002060.1_2 - 0.00091 20.0 0.1 0.0011 19.7 0.1 1.1 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain CSD PF00313.22 AAAP01002060.1_2 - 0.038 13.8 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF1344 PF07076.11 AAAP01002060.1_2 - 0.049 13.6 1.3 1.6 8.7 1.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1344) YtxH PF12732.7 AAAP01002061.1_1 - 0.3 11.7 0.4 0.3 11.7 0.4 1.7 2 0 0 2 2 2 0 YtxH-like protein Tetraspanin PF00335.20 AAAP01002061.1_1 - 0.54 9.9 3.1 0.56 9.9 3.1 1.1 1 0 0 1 1 1 0 Tetraspanin family OPT PF03169.15 AAAP01002062.1_2 - 1.8e-43 149.2 6.3 2.5e-43 148.6 6.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PGM1_C PF18105.1 AAAP01002062.1_2 - 0.032 13.7 2.2 0.31 10.6 2.2 2.8 1 1 0 1 1 1 0 PGM1 C-terminal domain DUF4240 PF14024.6 AAAP01002063.1_1 - 6.4e-28 97.5 0.0 8.3e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4240) CobS PF02654.15 AAAP01002063.1_1 - 0.07 13.3 0.3 0.095 12.9 0.3 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase BBE PF08031.12 AAAP01002063.1_2 - 0.0071 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like VapB_antitoxin PF09957.9 AAAP01002064.1_3 - 0.014 15.3 0.3 0.045 13.7 0.6 1.7 1 1 1 2 2 2 0 Bacterial antitoxin of type II TA system, VapB GST_N PF02798.20 AAAP01002065.1_2 - 1.5e-12 47.7 0.0 2.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAAP01002065.1_2 - 2.9e-12 46.8 0.0 5.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01002065.1_2 - 3.6e-10 40.0 0.0 7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01002065.1_2 - 6.7e-07 29.2 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAAP01002065.1_2 - 2.9e-06 27.4 0.0 4.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAAP01002065.1_2 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAAP01002065.1_2 - 0.14 12.0 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Hydantoinase_B PF02538.14 AAAP01002066.1_1 - 1.3e-50 172.3 4.6 1.5e-50 172.1 4.6 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.13 AAAP01002066.1_2 - 8.3e-15 54.9 0.4 1e-14 54.7 0.4 1.0 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 AAAP01002066.1_2 - 0.03 12.9 0.0 0.034 12.7 0.0 1.0 1 0 0 1 1 1 0 MutL protein Peptidase_M3 PF01432.20 AAAP01002067.1_3 - 3.6e-26 92.4 0.0 4e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 ParB_C PF18064.1 AAAP01002068.1_1 - 0.00069 19.7 0.0 0.00083 19.5 0.0 1.2 1 0 0 1 1 1 1 Centromere-binding protein ParB C-terminal DUF4192 PF13830.6 AAAP01002068.1_3 - 4.3e-17 63.2 10.8 5.3e-17 62.9 10.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) DUF3869 PF12985.7 AAAP01002068.1_3 - 0.093 13.1 0.5 0.18 12.2 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3869) Phosphorylase PF00343.20 AAAP01002070.1_1 - 7.8e-100 335.2 0.0 9.7e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Response_reg PF00072.24 AAAP01002071.1_1 - 2.6e-22 79.1 0.0 4.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA_2 PF07568.12 AAAP01002071.1_1 - 1e-20 73.6 0.4 1e-20 73.6 0.4 1.7 2 0 0 2 2 2 1 Histidine kinase HWE_HK PF07536.14 AAAP01002071.1_1 - 9.2e-08 32.7 0.6 2.4e-07 31.4 0.6 1.7 1 0 0 1 1 1 1 HWE histidine kinase ASL_C PF08328.11 AAAP01002071.1_1 - 0.15 12.2 0.5 1.4 9.1 0.1 2.1 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal SIMPL PF04402.14 AAAP01002071.1_1 - 0.41 11.1 3.3 0.68 10.4 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Response_reg PF00072.24 AAAP01002071.1_2 - 6e-08 32.8 0.0 6.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Glycos_transf_4 PF00953.21 AAAP01002073.1_1 - 4.9e-17 62.4 4.6 4.9e-17 62.4 4.6 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 4 Epimerase PF01370.21 AAAP01002073.1_2 - 1.7e-28 99.7 0.0 2.2e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01002073.1_2 - 6.1e-26 91.4 0.2 7.2e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAAP01002073.1_2 - 1.2e-18 67.2 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01002073.1_2 - 4.8e-17 61.9 0.0 7.7e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01002073.1_2 - 6.1e-13 48.5 0.3 2.8e-07 30.0 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 AAAP01002073.1_2 - 7e-11 42.1 0.0 1.3e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AAAP01002073.1_2 - 1.6e-09 37.7 0.1 1e-08 35.0 0.1 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAAP01002073.1_2 - 1.2e-05 24.7 0.1 0.0026 17.0 0.1 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 AAAP01002073.1_2 - 0.0029 17.5 2.7 0.27 11.1 2.7 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 AAAP01002073.1_2 - 0.028 13.9 0.2 0.23 10.9 0.1 2.4 2 1 0 2 2 2 0 short chain dehydrogenase Glyco_trans_4_4 PF13579.6 AAAP01002073.1_2 - 3.5 8.1 16.6 13 6.2 11.4 3.2 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain SBP_bac_3 PF00497.20 AAAP01002074.1_1 - 3.3e-14 52.8 0.0 5.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HPPK PF01288.20 AAAP01002074.1_2 - 0.00072 20.1 0.3 0.001 19.5 0.3 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NotI PF12183.8 AAAP01002075.1_2 - 0.04 13.2 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NotI ERp29 PF07749.12 AAAP01002075.1_3 - 0.014 16.3 0.2 0.016 16.1 0.2 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1127 PF06568.11 AAAP01002075.1_3 - 0.039 13.7 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) CitMHS PF03600.16 AAAP01002076.1_2 - 8.9e-20 71.1 13.4 1.2e-19 70.7 13.4 1.2 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.15 AAAP01002076.1_2 - 4.5e-15 55.9 10.4 5.4e-15 55.6 10.4 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein Na_sulph_symp PF00939.19 AAAP01002076.1_2 - 8.2e-11 41.6 10.4 1e-10 41.3 10.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region MatC_N PF07158.11 AAAP01002076.1_2 - 6.2e-08 32.8 5.4 6.2e-08 32.8 5.4 1.6 1 1 0 1 1 1 1 Dicarboxylate carrier protein MatC N-terminus Carboxyl_trans PF01039.22 AAAP01002077.1_1 - 8.6e-103 344.6 0.1 1e-102 344.3 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain BPD_transp_2 PF02653.16 AAAP01002078.1_1 - 8.8e-12 44.7 17.1 9.1e-12 44.7 17.1 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Claudin_2 PF13903.6 AAAP01002078.1_1 - 3.9 7.2 8.3 0.64 9.7 4.3 1.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction BPD_transp_2 PF02653.16 AAAP01002078.1_2 - 3.2e-26 92.1 12.8 4e-26 91.8 12.8 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component TonB_dep_Rec PF00593.24 AAAP01002080.1_1 - 1.1e-23 84.9 22.4 1.4e-23 84.6 22.4 1.1 1 0 0 1 1 1 1 TonB dependent receptor DUF4158 PF13700.6 AAAP01002081.1_2 - 0.0086 15.9 1.2 0.012 15.4 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) 4HBT PF03061.22 AAAP01002081.1_3 - 3.3e-08 33.8 0.1 4.9e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF465 PF04325.13 AAAP01002082.1_1 - 4.5e-15 55.4 7.9 5.2e-15 55.2 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF465) ABC_tran_CTD PF16326.5 AAAP01002082.1_1 - 0.043 14.1 3.2 0.1 12.9 3.2 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF1192 PF06698.11 AAAP01002082.1_1 - 0.076 13.1 4.2 0.073 13.1 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.15 AAAP01002082.1_1 - 0.084 12.7 4.0 0.64 9.8 0.9 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF5595 PF18077.1 AAAP01002082.1_1 - 0.12 12.5 3.6 2.2 8.4 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) ZapB PF06005.12 AAAP01002082.1_1 - 0.16 12.4 4.7 0.92 10.0 1.0 2.0 1 1 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 AAAP01002082.1_1 - 0.32 11.1 5.3 2.3 8.4 1.6 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Lzipper-MIP1 PF14389.6 AAAP01002082.1_1 - 0.38 11.1 6.8 1.4 9.3 0.8 2.0 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cep57_CLD_2 PF14197.6 AAAP01002082.1_1 - 0.43 10.7 8.6 0.67 10.1 8.6 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 HalX PF08663.10 AAAP01002082.1_1 - 0.63 10.4 6.0 7.1 7.0 6.0 2.2 1 1 0 1 1 1 0 HalX domain LINES_C PF14695.6 AAAP01002082.1_1 - 1.1 8.8 3.3 21 4.7 0.1 2.9 2 1 1 3 3 3 0 Lines C-terminus DUF465 PF04325.13 AAAP01002082.1_2 - 9e-14 51.2 9.6 1.3e-13 50.8 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF465) Spc7 PF08317.11 AAAP01002082.1_2 - 0.011 14.6 0.7 0.012 14.6 0.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein CAGE1 PF15066.6 AAAP01002082.1_2 - 0.027 13.2 0.2 0.028 13.1 0.2 1.0 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family C4bp_oligo PF18453.1 AAAP01002082.1_2 - 0.06 13.5 1.3 0.1 12.8 1.3 1.4 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha SlyX PF04102.12 AAAP01002082.1_2 - 0.13 12.9 4.4 0.28 11.8 4.5 1.5 1 1 1 2 2 2 0 SlyX Ribonuc_L-PSP PF01042.21 AAAP01002083.1_3 - 2.1e-19 69.7 0.0 2.7e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Herpes_VP19C PF03327.14 AAAP01002084.1_1 - 0.19 11.1 0.0 0.2 11.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C NadA PF02445.16 AAAP01002085.1_1 - 3.2e-58 197.2 1.2 4e-58 196.9 1.2 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein NadA PF02445.16 AAAP01002085.1_2 - 7.3e-25 87.7 0.1 8.1e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein APH PF01636.23 AAAP01002086.1_1 - 6.5e-15 55.7 0.8 7.7e-15 55.5 0.8 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Filaggrin PF03516.13 AAAP01002086.1_1 - 0.17 12.6 5.0 0.29 11.9 5.0 1.3 1 0 0 1 1 1 0 Filaggrin Pilosulin PF17499.2 AAAP01002086.1_2 - 0.087 13.0 1.5 0.1 12.8 0.2 1.8 1 1 1 2 2 2 0 Ant venom peptides Methyltransf_25 PF13649.6 AAAP01002086.1_3 - 1.2e-15 58.0 0.1 2.5e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002086.1_3 - 2.3e-11 44.2 0.1 4.2e-11 43.3 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002086.1_3 - 4.4e-11 43.4 0.0 7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002086.1_3 - 3.5e-10 40.0 0.0 5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002086.1_3 - 5.2e-09 36.1 0.0 7.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 AAAP01002086.1_3 - 3.9e-06 26.5 0.0 2.2e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 AAAP01002086.1_3 - 0.0001 21.9 0.0 0.00015 21.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AAAP01002086.1_3 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 AAAP01002086.1_3 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 AAAP01002086.1_3 - 0.028 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.11 AAAP01002086.1_3 - 0.032 13.9 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AAAP01002086.1_3 - 0.046 13.7 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 AAAP01002086.1_3 - 0.047 13.8 0.0 0.057 13.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.11 AAAP01002086.1_3 - 0.057 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 AAAP01002086.1_3 - 0.21 11.3 0.0 0.68 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Resolvase PF00239.21 AAAP01002087.1_1 - 5.9e-31 107.5 2.7 7.5e-31 107.2 2.7 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_IclR PF09339.10 AAAP01002087.1_1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.15 AAAP01002087.1_1 - 0.00024 21.1 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AAAP01002087.1_1 - 0.002 18.1 0.1 0.037 14.0 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01002087.1_1 - 0.0061 16.3 0.4 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain TetR_N PF00440.23 AAAP01002087.1_1 - 0.0089 15.8 0.6 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_28 PF13518.6 AAAP01002087.1_1 - 0.012 15.8 0.3 0.04 14.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 AAAP01002087.1_1 - 0.012 15.7 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 HTH domain Sigma70_r4_2 PF08281.12 AAAP01002087.1_1 - 0.038 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.19 AAAP01002087.1_1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DnaB_2 PF07261.11 AAAP01002087.1_1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment MarR_2 PF12802.7 AAAP01002087.1_1 - 0.076 12.9 0.3 0.3 11.0 0.0 2.2 3 0 0 3 3 3 0 MarR family HTH_17 PF12728.7 AAAP01002087.1_1 - 0.081 13.1 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01002087.1_1 - 0.16 11.8 2.9 0.34 10.7 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3383 PF11863.8 AAAP01002088.1_1 - 3e-68 231.0 1.1 3.4e-68 230.8 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3383) DUF3277 PF11681.8 AAAP01002088.1_2 - 6.2e-50 168.8 1.2 7e-50 168.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) PMT_2 PF13231.6 AAAP01002089.1_1 - 1.9e-06 28.2 14.8 1.9e-06 28.2 14.8 2.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 AAAP01002089.1_1 - 4.7e-05 23.1 6.9 4.7e-05 23.1 6.9 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PAS PF00989.25 AAAP01002090.1_1 - 6.2e-05 23.0 0.0 7.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 PAS fold MLTR_LBD PF17765.1 AAAP01002090.1_1 - 0.0059 16.8 0.2 0.0066 16.6 0.2 1.1 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain PAS_4 PF08448.10 AAAP01002090.1_1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.7 AAAP01002090.1_1 - 0.018 15.0 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 PAS domain Peptidase_S11 PF00768.20 AAAP01002091.1_1 - 1.6e-30 106.3 0.0 1.2e-29 103.5 0.0 2.0 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase SPOR PF05036.13 AAAP01002091.1_1 - 0.029 14.7 0.0 0.098 13.1 0.0 1.9 1 0 0 1 1 1 0 Sporulation related domain Glyco_trans_4_3 PF12000.8 AAAP01002092.1_2 - 1.9e-29 102.5 0.0 2e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 4 group CobT_C PF11775.8 AAAP01002093.1_2 - 1.7e-118 394.0 0.0 2.2e-118 393.6 0.0 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain CobT PF06213.12 AAAP01002093.1_2 - 8e-09 35.3 12.7 1.6e-08 34.3 12.7 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA_2 PF13519.6 AAAP01002093.1_2 - 0.0038 17.9 0.0 1.4 9.6 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 AAAP01002093.1_2 - 0.011 15.9 0.0 5.4 7.2 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain SDA1 PF05285.12 AAAP01002093.1_2 - 6.3 6.1 17.2 8.6 5.7 17.2 1.1 1 0 0 1 1 1 0 SDA1 Pentapeptide PF00805.22 AAAP01002094.1_1 - 3e-08 33.2 2.2 3.7e-07 29.7 1.6 2.3 2 1 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAAP01002094.1_1 - 0.22 11.7 0.0 0.38 10.9 0.0 1.5 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Aldedh PF00171.22 AAAP01002095.1_1 - 1.6e-76 257.7 0.0 1.9e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Orn_DAP_Arg_deC PF00278.22 AAAP01002095.1_2 - 4.7e-16 58.8 0.0 1.3e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HisKA PF00512.25 AAAP01002096.1_1 - 7.8e-17 61.1 3.0 9.7e-17 60.8 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAAP01002096.1_1 - 2e-13 50.8 0.0 3.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01002096.1_1 - 2e-09 37.7 2.5 2e-09 37.7 2.5 2.3 2 0 0 2 2 2 1 HAMP domain Ribosomal_L17 PF01196.19 AAAP01002096.1_1 - 0.027 15.4 0.1 0.074 13.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L17 HATPase_c_2 PF13581.6 AAAP01002096.1_1 - 0.048 13.6 1.5 0.15 12.0 0.0 2.4 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain MIF4G_like_2 PF09090.11 AAAP01002096.1_1 - 0.059 12.8 0.2 0.36 10.3 0.2 2.0 1 1 0 1 1 1 0 MIF4G like Response_reg PF00072.24 AAAP01002096.1_2 - 2.9e-23 82.2 0.0 7.9e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01002096.1_2 - 2.1e-18 66.2 0.0 4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Cu-oxidase_4 PF02578.15 AAAP01002097.1_1 - 1.7e-22 80.2 0.0 1.8e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Cu-oxidase_4 PF02578.15 AAAP01002097.1_2 - 1.2e-18 67.6 0.0 1.4e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase HrpB_C PF08482.10 AAAP01002098.1_2 - 2e-38 131.8 0.0 2.4e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Lum_binding PF00677.17 AAAP01002099.1_1 - 7.8e-41 138.0 0.1 6.1e-20 71.0 0.0 2.0 2 0 0 2 2 2 2 Lumazine binding domain GtrA PF04138.14 AAAP01002099.1_2 - 6e-18 65.2 4.7 7.2e-18 64.9 4.7 1.1 1 0 0 1 1 1 1 GtrA-like protein DUF1700 PF08006.11 AAAP01002099.1_2 - 0.15 11.6 1.4 0.2 11.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Ribosomal_S17 PF00366.20 AAAP01002100.1_1 - 1.1e-20 73.5 1.6 1.2e-20 73.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 AAAP01002100.1_2 - 1.2e-45 154.6 4.4 1.3e-45 154.4 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Lpp-LpqN PF10738.9 AAAP01002101.1_2 - 0.15 11.6 1.9 0.16 11.4 1.9 1.1 1 0 0 1 1 1 0 Probable lipoprotein LpqN DDE_Tnp_1_2 PF13586.6 AAAP01002102.1_1 - 3.4e-19 69.0 0.3 3.9e-19 68.8 0.3 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01002102.1_1 - 8.5e-05 22.3 0.4 0.0029 17.3 0.4 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01002102.1_1 - 0.0072 16.0 0.0 0.0089 15.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease NPAT_C PF15712.5 AAAP01002103.1_1 - 0.015 14.0 0.5 0.02 13.6 0.5 1.1 1 0 0 1 1 1 0 NPAT C terminus AAA_PrkA PF08298.11 AAAP01002103.1_2 - 1e-22 80.5 0.0 1.1e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 PrkA AAA domain YkuD PF03734.14 AAAP01002104.1_1 - 7e-06 26.5 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PhzC-PhzF PF02567.16 AAAP01002105.1_1 - 3.7e-20 72.6 0.0 4.2e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HTH_15 PF12324.8 AAAP01002105.1_1 - 0.15 12.0 1.8 15 5.6 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase MFS_1 PF07690.16 AAAP01002105.1_2 - 8e-09 34.9 13.8 8.6e-09 34.8 13.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAAP01002105.1_2 - 0.0013 17.4 1.7 0.0015 17.2 1.7 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 AAAP01002105.1_2 - 0.0017 17.3 1.1 0.0018 17.2 1.1 1.1 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 AAAP01002105.1_2 - 0.013 14.5 0.4 0.014 14.4 0.4 1.2 1 0 0 1 1 1 0 Nucleoside H+ symporter HTH_Tnp_1 PF01527.20 AAAP01002106.1_1 - 1.4e-20 73.3 0.2 1.5e-20 73.2 0.2 1.0 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAAP01002106.1_1 - 1.9e-07 31.1 0.1 2.5e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01002106.1_1 - 2.1e-07 30.9 0.1 4.2e-07 29.9 0.0 1.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01002106.1_1 - 5.8e-07 29.1 0.0 8.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AAAP01002106.1_1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 AAAP01002106.1_1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase CENP-B_N PF04218.13 AAAP01002106.1_1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Terminase_5 PF06056.12 AAAP01002106.1_1 - 0.037 13.9 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.6 AAAP01002106.1_1 - 0.08 13.5 0.0 0.08 13.5 0.0 1.2 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 AAAP01002106.1_1 - 0.095 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Phage_pRha PF09669.10 AAAP01002106.1_3 - 1.1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) E1-E2_ATPase PF00122.20 AAAP01002107.1_2 - 4.1e-22 78.6 0.2 4.1e-22 78.6 0.2 2.1 2 1 0 2 2 2 1 E1-E2 ATPase TatC PF00902.18 AAAP01002107.1_2 - 0.9 9.3 6.7 3.7 7.3 3.0 2.2 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) Flg_hook PF02120.16 AAAP01002108.1_1 - 3e-14 52.7 0.2 5.1e-14 51.9 0.2 1.3 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK B12-binding PF02310.19 AAAP01002109.1_2 - 2.2e-12 47.1 0.0 3.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AAAP01002109.1_2 - 0.02 15.3 0.1 0.043 14.3 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain Methyltransf_14 PF08484.11 AAAP01002111.1_1 - 5e-44 149.9 0.0 5.4e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Regnase_1_C PF18561.1 AAAP01002111.1_1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain dTDP_sugar_isom PF00908.17 AAAP01002111.1_2 - 4.8e-45 153.3 0.0 5.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Ferrochelatase PF00762.19 AAAP01002112.1_1 - 2.9e-27 95.6 0.0 3.3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Chlor_dismutase PF06778.12 AAAP01002112.1_2 - 8.8e-22 77.6 0.0 1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Chlorite dismutase Iso_dh PF00180.20 AAAP01002113.1_1 - 8.9e-53 179.6 0.0 1.1e-52 179.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1013 PF06242.11 AAAP01002114.1_1 - 9.5e-63 210.4 0.1 1.2e-62 210.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1013) RuvB_N PF05496.12 AAAP01002115.1_1 - 2.7e-78 261.2 0.1 3.7e-78 260.8 0.1 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AAAP01002115.1_1 - 5.5e-30 102.9 1.7 1.2e-29 101.8 1.7 1.6 1 0 0 1 1 1 1 RuvB AAA lid domain AAA PF00004.29 AAAP01002115.1_1 - 4.6e-20 72.4 0.0 1.1e-19 71.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_C PF05491.13 AAAP01002115.1_1 - 5.1e-12 45.5 0.0 9.3e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA_5 PF07728.14 AAAP01002115.1_1 - 2.4e-10 40.5 0.4 2.1e-07 31.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAAP01002115.1_1 - 2.2e-07 30.4 0.2 3.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 AAAP01002115.1_1 - 1.9e-05 24.2 1.0 0.0058 16.0 0.1 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAAP01002115.1_1 - 2.2e-05 24.7 1.7 0.093 13.0 0.0 3.3 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AAAP01002115.1_1 - 2.8e-05 24.6 0.3 0.0042 17.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 AAAP01002115.1_1 - 3.4e-05 23.6 0.0 0.16 11.7 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 AAAP01002115.1_1 - 4.9e-05 23.2 0.0 0.0088 15.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAAP01002115.1_1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAAP01002115.1_1 - 0.00071 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AAAP01002115.1_1 - 0.00076 19.5 0.0 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 AAAP01002115.1_1 - 0.00096 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 AAAP01002115.1_1 - 0.0013 19.3 0.0 0.0023 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AAAP01002115.1_1 - 0.0026 17.9 0.0 0.061 13.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 AAAP01002115.1_1 - 0.0026 18.2 0.0 0.006 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AAAP01002115.1_1 - 0.003 17.6 0.1 1.2 9.1 0.0 2.2 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AAAP01002115.1_1 - 0.0033 17.3 0.3 0.084 12.8 0.0 2.2 1 1 1 2 2 2 1 NTPase DUF815 PF05673.13 AAAP01002115.1_1 - 0.0078 15.4 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 AAAP01002115.1_1 - 0.0091 15.2 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain MCM PF00493.23 AAAP01002115.1_1 - 0.012 14.7 0.0 1.1 8.3 0.0 2.2 1 1 1 2 2 2 0 MCM P-loop domain RNA_helicase PF00910.22 AAAP01002115.1_1 - 0.02 15.3 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 AAAP01002115.1_1 - 0.022 14.5 0.3 0.16 11.7 0.3 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 AAAP01002115.1_1 - 0.03 14.9 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 AAAP01002115.1_1 - 0.031 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 AAAP01002115.1_1 - 0.037 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AAAP01002115.1_1 - 0.043 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 AAAP01002115.1_1 - 0.055 13.2 1.4 3 7.5 0.2 2.9 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.18 AAAP01002115.1_1 - 0.056 13.3 0.1 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_28 PF13521.6 AAAP01002115.1_1 - 0.084 13.1 0.0 0.21 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 AAAP01002115.1_1 - 0.11 12.9 1.7 4.5 7.6 0.1 2.5 2 1 1 3 3 2 0 AAA domain TniB PF05621.11 AAAP01002115.1_1 - 0.12 11.8 0.1 2.2 7.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 AAAP01002115.1_1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PG_binding_1 PF01471.18 AAAP01002115.1_2 - 3.4e-07 30.4 0.0 5.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain TonB_N PF16031.5 AAAP01002115.1_2 - 0.34 11.4 16.7 0.62 10.6 16.7 1.4 1 0 0 1 1 1 0 TonB polyproline region Phage_capsid PF05065.13 AAAP01002116.1_1 - 4.5e-55 186.9 0.1 5.2e-55 186.7 0.1 1.0 1 0 0 1 1 1 1 Phage capsid family GAF_3 PF13492.6 AAAP01002116.1_1 - 0.12 12.7 0.3 13 6.1 0.0 2.7 3 0 0 3 3 3 0 GAF domain PAS_4 PF08448.10 AAAP01002116.1_1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 PAS fold PaaX PF07848.12 AAAP01002116.1_2 - 0.2 11.9 0.0 0.21 11.8 0.0 1.0 1 0 0 1 1 1 0 PaaX-like protein AI-2E_transport PF01594.16 AAAP01002117.1_1 - 2.5e-15 56.5 23.1 2.8e-15 56.3 23.1 1.0 1 0 0 1 1 1 1 AI-2E family transporter Kdo_hydroxy PF11004.8 AAAP01002117.1_2 - 4.1e-82 275.5 0.0 4.6e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF4538 PF15061.6 AAAP01002119.1_1 - 0.03 14.0 0.2 0.051 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) BPD_transp_1 PF00528.22 AAAP01002119.1_2 - 0.00018 21.3 3.7 0.00018 21.3 3.7 2.2 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MFS_MOT1 PF16983.5 AAAP01002119.1_2 - 0.012 16.1 3.5 0.053 13.9 0.6 2.5 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily DivIC PF04977.15 AAAP01002120.1_2 - 0.17 11.7 0.9 0.34 10.7 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Prenyltransf PF01255.19 AAAP01002121.1_1 - 9.9e-72 241.1 0.0 1.1e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Glyoxalase_6 PF18029.1 AAAP01002121.1_2 - 2.6e-24 86.1 1.2 3e-24 85.9 1.2 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain DUF1970 PF09301.10 AAAP01002121.1_2 - 0.12 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Abhydrolase_6 PF12697.7 AAAP01002122.1_2 - 4e-08 34.1 17.7 5.2e-08 33.8 17.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01002122.1_2 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 AAAP01002123.1_2 - 4.8e-27 94.6 0.0 6.2e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme E1-E2_ATPase PF00122.20 AAAP01002124.1_2 - 8.6e-13 48.2 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase TIR_2 PF13676.6 AAAP01002124.1_3 - 6.2e-14 52.6 0.0 8.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 AAAP01002124.1_3 - 0.0021 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 AAAP01002124.1_3 - 0.011 16.0 0.0 0.039 14.3 0.0 1.9 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF736 PF05284.12 AAAP01002125.1_1 - 2.8e-33 113.8 0.0 3.1e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF736) HTH_31 PF13560.6 AAAP01002125.1_2 - 5.6e-06 26.6 4.2 9.2e-06 25.9 4.2 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01002125.1_2 - 1.4e-05 25.0 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 AAAP01002125.1_2 - 0.001 18.9 0.1 0.0015 18.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01002125.1_2 - 0.018 15.1 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2285 PF10074.9 AAAP01002125.1_3 - 0.0087 16.7 0.0 0.01 16.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2285) zf-HC2 PF13490.6 AAAP01002126.1_1 - 0.0058 16.8 1.7 0.022 15.0 0.1 2.7 3 0 0 3 3 3 1 Putative zinc-finger RskA PF10099.9 AAAP01002126.1_1 - 0.097 13.0 17.9 0.017 15.4 14.4 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Sigma70_r4_2 PF08281.12 AAAP01002126.1_2 - 2.6e-07 30.2 0.0 4.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01002126.1_2 - 1.4e-06 27.8 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 GTP_EFTU_D2 PF03144.25 AAAP01002127.1_1 - 6.9e-05 23.2 0.0 9.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Tox-ART-HYD1 PF15633.6 AAAP01002128.1_1 - 0.03 15.0 0.0 0.041 14.6 0.0 1.3 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase LacI PF00356.21 AAAP01002128.1_2 - 0.08 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Oxidored_nitro PF00148.19 AAAP01002129.1_1 - 2.4e-05 23.2 0.1 2.9e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF4920 PF16267.5 AAAP01002129.1_1 - 0.23 11.5 0.0 0.53 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) Oxidored_nitro PF00148.19 AAAP01002129.1_2 - 1.8e-29 102.7 0.0 2.2e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Porin_O_P PF07396.11 AAAP01002131.1_1 - 2.1e-36 125.9 0.0 2.4e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate-selective porin O and P DUF3168 PF11367.8 AAAP01002132.1_1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Sod_Cu PF00080.20 AAAP01002132.1_2 - 3.3e-33 114.9 1.7 4.2e-33 114.5 1.7 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CheW PF01584.19 AAAP01002133.1_2 - 3.6e-31 107.7 0.3 4.6e-31 107.3 0.3 1.1 1 0 0 1 1 1 1 CheW-like domain Zn_Tnp_IS1595 PF12760.7 AAAP01002135.1_1 - 1.3e-08 34.6 3.6 1.7e-08 34.3 3.6 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAAP01002135.1_1 - 0.0014 18.7 1.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 AAAP01002135.1_1 - 0.0021 17.9 0.7 0.0023 17.8 0.7 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 AAAP01002135.1_1 - 0.0023 17.4 1.4 0.0033 16.9 1.4 1.3 1 1 0 1 1 1 1 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 AAAP01002135.1_1 - 0.02 14.8 0.1 0.038 14.0 0.1 1.5 1 1 0 1 1 1 0 PhnA Zinc-Ribbon TFIIS_C PF01096.18 AAAP01002135.1_1 - 0.023 14.6 2.2 2.3 8.2 2.2 2.2 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 AAAP01002135.1_1 - 0.023 14.6 1.1 0.11 12.4 1.1 1.9 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 AAAP01002135.1_1 - 0.028 13.8 1.3 0.94 9.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AAAP01002135.1_1 - 0.031 14.2 3.5 0.054 13.4 3.5 1.4 1 1 0 1 1 1 0 Nudix N-terminal zf-HYPF PF07503.12 AAAP01002135.1_1 - 0.036 13.8 2.4 0.26 11.1 2.4 2.0 1 1 0 1 1 1 0 HypF finger CpXC PF14353.6 AAAP01002135.1_1 - 0.04 13.9 0.4 3.9 7.5 0.0 2.0 1 1 1 2 2 2 0 CpXC protein Mu-like_Com PF10122.9 AAAP01002135.1_1 - 0.042 13.3 1.7 0.31 10.5 0.1 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.6 AAAP01002135.1_1 - 0.16 11.8 2.7 1.7 8.4 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 AAAP01002135.1_1 - 0.27 11.3 1.0 0.5 10.4 1.0 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 AAAP01002135.1_1 - 0.32 10.6 1.1 9.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 AAAP01002135.1_1 - 0.34 11.0 1.8 9.8 6.4 0.2 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Rubredoxin_2 PF18073.1 AAAP01002135.1_1 - 0.36 10.6 5.0 1.8 8.4 0.7 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Prok-RING_1 PF14446.6 AAAP01002135.1_1 - 0.36 10.8 2.4 8.2 6.4 0.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_10 PF10058.9 AAAP01002135.1_1 - 0.37 10.6 2.4 4.5 7.1 0.2 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 AAAP01002135.1_1 - 1.8 8.6 5.7 71 3.4 5.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-ISL3 PF14690.6 AAAP01002135.1_1 - 2 9.2 7.2 20 5.9 1.5 2.2 1 1 2 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MetOD1 PF18546.1 AAAP01002135.1_3 - 0.002 18.1 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Metanogen output domain 1 Sigma70_r4 PF04545.16 AAAP01002136.1_2 - 3.1e-17 61.8 2.9 6.8e-16 57.5 0.4 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AAAP01002136.1_2 - 0.00067 19.3 0.2 0.021 14.5 0.1 2.7 2 1 0 2 2 2 1 Sigma-70, region 4 HTH_19 PF12844.7 AAAP01002136.1_2 - 0.00095 19.1 0.0 0.32 11.0 0.0 2.6 3 0 0 3 3 3 2 Helix-turn-helix domain Sigma70_r3 PF04539.16 AAAP01002136.1_2 - 0.0023 18.0 0.3 0.015 15.4 0.1 2.1 2 0 0 2 2 2 1 Sigma-70 region 3 HTH_11 PF08279.12 AAAP01002136.1_2 - 0.013 15.5 0.2 0.065 13.2 0.0 2.2 2 0 0 2 2 2 0 HTH domain GntR PF00392.21 AAAP01002136.1_2 - 0.056 13.1 0.1 0.35 10.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family KORA PF16509.5 AAAP01002136.1_2 - 0.075 13.3 0.0 4 7.8 0.0 2.5 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Transpeptidase PF00905.22 AAAP01002137.1_1 - 1.2e-23 83.8 0.0 3.1e-16 59.5 0.0 2.0 2 0 0 2 2 2 2 Penicillin binding protein transpeptidase domain OprB PF04966.12 AAAP01002138.1_1 - 5.8e-19 68.7 0.8 7.7e-19 68.3 0.8 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Cupin_2 PF07883.11 AAAP01002139.1_1 - 2.3e-09 36.8 0.1 3.1e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AAAP01002139.1_1 - 2.5e-05 23.9 0.0 2.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.12 AAAP01002139.1_1 - 0.039 13.4 0.1 0.039 13.4 0.1 1.1 1 0 0 1 1 1 0 Cupin superfamily protein HSP20 PF00011.21 AAAP01002139.1_3 - 2e-17 63.2 0.0 2.2e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01002139.1_3 - 0.0039 16.7 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PrmA PF06325.13 AAAP01002140.1_1 - 5.8e-55 186.8 0.0 6.8e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 AAAP01002140.1_1 - 7.9e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002140.1_1 - 1.5e-07 32.0 0.0 2.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01002140.1_1 - 6.6e-07 29.0 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AAAP01002140.1_1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002140.1_1 - 0.0014 19.2 0.0 0.0027 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AAAP01002140.1_1 - 0.0059 16.6 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AAAP01002140.1_1 - 0.0077 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 AAAP01002140.1_1 - 0.033 14.1 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002140.1_1 - 0.14 13.0 0.0 0.26 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 AAAP01002140.1_1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Creatinase_N PF01321.18 AAAP01002140.1_2 - 1.1e-08 35.7 0.0 1.2e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain HisKA PF00512.25 AAAP01002141.1_2 - 6.2e-19 67.8 0.4 3.3e-18 65.5 0.0 2.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01002141.1_2 - 4.4e-05 23.7 0.7 0.00015 22.0 0.7 2.0 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01002141.1_2 - 0.00023 21.1 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AAAP01002141.1_2 - 0.004 17.6 0.0 0.0093 16.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAAP01002141.1_2 - 0.02 15.2 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 PAS fold AraC_binding_2 PF14525.6 AAAP01002142.1_1 - 3.7e-19 69.1 0.5 4.7e-19 68.7 0.5 1.2 1 0 0 1 1 1 1 AraC-binding-like domain Cupin_6 PF12852.7 AAAP01002142.1_1 - 0.027 14.2 0.1 0.067 12.9 0.1 1.7 1 1 0 1 1 1 0 Cupin Glycos_transf_1 PF00534.20 AAAP01002143.1_1 - 1.3e-22 80.2 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01002143.1_1 - 8.7e-22 78.0 0.0 1.7e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01002143.1_1 - 3.6e-21 76.3 13.6 3.6e-21 76.3 13.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01002143.1_1 - 1.6e-19 70.5 4.7 4.6e-19 69.0 3.5 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 STAS_2 PF13466.6 AAAP01002143.1_1 - 9.7 6.6 18.0 3 8.2 0.9 4.2 3 1 0 4 4 4 0 STAS domain AbrB-like PF14250.6 AAAP01002144.1_1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AbrB-like transcriptional regulator FtsX PF02687.21 AAAP01002144.1_2 - 0.0002 21.8 0.0 0.00021 21.7 0.0 1.1 1 0 0 1 1 1 1 FtsX-like permease family ABC_tran PF00005.27 AAAP01002144.1_3 - 1.9e-32 112.6 0.0 2.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002144.1_3 - 0.00062 19.7 0.1 0.27 11.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01002144.1_3 - 0.005 16.6 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAAP01002144.1_3 - 0.016 14.6 0.0 0.95 8.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01002144.1_3 - 0.02 14.8 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 AAAP01002144.1_3 - 0.025 13.4 0.0 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAAP01002144.1_3 - 0.03 14.7 1.8 0.047 14.1 1.8 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01002144.1_3 - 0.074 13.3 0.1 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAAP01002144.1_3 - 0.077 13.2 1.3 1.7 9.0 0.9 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AAAP01002144.1_3 - 0.15 12.1 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF5131 PF07505.11 AAAP01002145.1_1 - 3.2e-96 321.5 0.1 3.8e-96 321.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) Plug PF07715.15 AAAP01002148.1_2 - 4.1e-18 65.9 1.3 1.3e-17 64.3 0.3 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain FtsK_gamma PF09397.10 AAAP01002148.1_3 - 2e-24 85.2 0.2 2.2e-24 85.0 0.2 1.0 1 0 0 1 1 1 1 Ftsk gamma domain ABC_tran PF00005.27 AAAP01002149.1_1 - 1.3e-26 93.7 0.0 1.8e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 AAAP01002149.1_1 - 7.8e-06 26.2 0.0 0.015 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AAAP01002149.1_1 - 0.0011 18.9 0.1 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AAAP01002149.1_1 - 0.0035 17.9 0.1 0.013 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01002149.1_1 - 0.0055 17.1 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAAP01002149.1_1 - 0.0058 16.4 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01002149.1_1 - 0.0074 16.0 0.2 1.8 8.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01002149.1_1 - 0.0079 16.6 0.6 0.024 15.0 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 AAAP01002149.1_1 - 0.014 15.2 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_21 PF13304.6 AAAP01002149.1_1 - 0.015 15.1 0.2 0.029 14.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01002149.1_1 - 0.018 14.5 0.0 5.3 6.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAAP01002149.1_1 - 0.024 14.8 0.2 0.067 13.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01002149.1_1 - 0.041 13.5 0.3 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01002149.1_1 - 0.041 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 AAAP01002149.1_1 - 0.044 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01002149.1_1 - 0.064 12.6 0.4 0.19 11.1 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF3987 PF13148.6 AAAP01002149.1_1 - 0.095 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 AAAP01002149.1_1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAAP01002149.1_1 - 0.18 12.0 0.6 1.3 9.3 0.6 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit VIT1 PF01988.19 AAAP01002151.1_1 - 4.1e-07 30.1 19.9 5.6e-05 23.1 4.5 2.6 2 1 1 3 3 3 2 VIT family Rubrerythrin PF02915.17 AAAP01002151.1_1 - 1.8e-06 28.4 0.0 2.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Rubrerythrin MDMPI_C PF07398.11 AAAP01002151.1_1 - 0.054 14.3 3.3 0.085 13.7 1.6 2.1 2 0 0 2 2 2 0 MDMPI C-terminal domain Ferritin_2 PF13668.6 AAAP01002151.1_1 - 0.11 12.7 1.2 0.24 11.6 0.7 1.7 1 1 0 1 1 1 0 Ferritin-like domain IucA_IucC PF04183.12 AAAP01002152.1_1 - 5.9e-65 219.2 0.0 7.4e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 IucA / IucC family WYL PF13280.6 AAAP01002153.1_1 - 5.6e-16 59.1 0.0 9.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 AAAP01002153.1_1 - 1.1e-14 54.1 0.1 1.8e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 AAAP01002153.1_1 - 2.3e-05 24.7 0.1 4.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 AAAP01002153.1_1 - 0.00035 20.1 0.1 0.00065 19.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAAP01002153.1_1 - 0.00094 19.0 1.1 0.00094 19.0 1.1 2.3 3 0 0 3 3 3 1 MarR family HTH_AsnC-type PF13404.6 AAAP01002153.1_1 - 0.0011 18.8 3.2 0.0011 18.8 3.2 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_DeoR PF08220.12 AAAP01002153.1_1 - 0.0024 17.6 0.4 0.0053 16.5 0.4 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_29 PF13551.6 AAAP01002153.1_1 - 0.0097 15.9 0.9 0.0097 15.9 0.9 2.7 4 0 0 4 4 4 1 Winged helix-turn helix HTH_36 PF13730.6 AAAP01002153.1_1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PaaX PF07848.12 AAAP01002153.1_1 - 0.023 14.9 0.4 0.046 13.9 0.4 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_23 PF13384.6 AAAP01002153.1_1 - 0.03 14.1 0.2 0.065 13.1 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Clp_N PF02861.20 AAAP01002153.1_1 - 0.03 14.4 0.4 0.067 13.3 0.4 1.6 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component HTH_28 PF13518.6 AAAP01002153.1_1 - 0.12 12.5 2.1 0.14 12.3 0.3 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 AAAP01002153.1_1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain WYL_2 PF10902.8 AAAP01002153.1_1 - 0.28 11.6 1.9 0.5 10.8 1.9 1.4 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold 3-dmu-9_3-mt PF06983.13 AAAP01002153.1_2 - 4.2e-08 33.7 0.0 6.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 AAAP01002153.1_2 - 1.4e-05 25.3 0.0 2.2e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Lactamase_B PF00753.27 AAAP01002154.1_1 - 0.00044 20.3 0.1 0.0006 19.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily HIPIP PF01355.17 AAAP01002154.1_1 - 0.047 14.0 0.5 0.12 12.8 0.3 1.7 2 0 0 2 2 2 0 High potential iron-sulfur protein Isochorismatase PF00857.20 AAAP01002155.1_2 - 7.9e-33 114.1 0.0 8.9e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family adh_short PF00106.25 AAAP01002155.1_3 - 7.6e-51 172.3 0.0 9.6e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002155.1_3 - 4.2e-37 128.0 0.0 5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01002155.1_3 - 4.6e-11 42.9 0.3 5.9e-11 42.6 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01002155.1_3 - 0.014 15.3 2.3 0.065 13.1 1.7 2.0 2 0 0 2 2 2 0 NAD(P)H-binding DFP PF04127.15 AAAP01002155.1_3 - 0.017 14.9 0.3 0.025 14.4 0.3 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 AAAP01002155.1_3 - 0.026 14.3 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.15 AAAP01002155.1_3 - 0.058 13.3 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 AAAP01002155.1_3 - 0.14 11.3 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Apolipoprotein PF01442.18 AAAP01002156.1_1 - 0.006 16.5 2.0 0.006 16.5 2.0 2.1 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain AMP-binding PF00501.28 AAAP01002157.1_1 - 1.1e-59 202.2 0.0 1.5e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Acyltransferase PF01553.21 AAAP01002157.1_1 - 0.00036 20.1 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase ABM PF03992.16 AAAP01002158.1_1 - 6.4e-10 39.0 0.6 6.4e-10 39.0 0.6 1.5 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 AAAP01002158.1_2 - 5.5e-22 78.2 69.4 4e-15 55.6 39.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.9 AAAP01002158.1_2 - 2.5 7.9 11.4 4.7 7.1 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) GATase_2 PF00310.21 AAAP01002159.1_1 - 1e-52 179.3 0.0 1.1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Oxidored_q5_N PF01059.17 AAAP01002160.1_1 - 2.7e-06 27.4 2.7 2.7e-06 27.4 2.7 2.1 1 1 0 2 2 2 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 AAAP01002160.1_1 - 5.3e-05 22.6 0.1 5.3e-05 22.6 0.1 2.1 3 0 0 3 3 3 1 Proton-conducting membrane transporter PetN PF03742.14 AAAP01002160.1_1 - 0.23 11.4 2.8 0.88 9.5 2.8 2.1 1 0 0 1 1 1 0 PetN DUF202 PF02656.15 AAAP01002160.1_1 - 4 8.0 8.5 0.2 12.1 2.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) NADH5_C PF06455.11 AAAP01002160.1_2 - 0.00043 19.9 0.0 0.00057 19.5 0.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase subunit 5 C-terminus CrgA PF06781.12 AAAP01002160.1_2 - 0.33 11.0 2.4 18 5.5 0.7 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF997 PF06196.12 AAAP01002160.1_2 - 0.79 9.8 3.9 0.26 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Plug PF07715.15 AAAP01002161.1_1 - 2.1e-10 41.2 0.3 3.9e-10 40.3 0.3 1.4 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain CDC27 PF09507.10 AAAP01002162.1_1 - 5 6.4 20.3 6.2 6.1 20.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.11 AAAP01002162.1_1 - 8 6.5 13.0 9.6 6.2 13.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PCMT PF01135.19 AAAP01002162.1_2 - 0.018 14.8 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zincin_2 PF10103.9 AAAP01002163.1_1 - 1.4e-08 34.4 0.2 1.5e-08 34.3 0.2 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase MazE_antitoxin PF04014.18 AAAP01002163.1_2 - 5.1e-06 26.3 0.2 9.9e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PIN PF01850.21 AAAP01002163.1_3 - 7.9e-19 68.4 0.0 8.9e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 AAAP01002163.1_3 - 0.006 17.3 0.0 0.009 16.8 0.0 1.3 1 0 0 1 1 1 1 PIN domain Peptidase_S13 PF02113.15 AAAP01002163.1_4 - 1.6e-53 182.0 1.0 4.3e-47 160.8 0.6 2.0 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 AAAP01002163.1_4 - 0.079 12.5 0.1 0.62 9.6 0.1 2.2 1 1 0 1 1 1 0 Beta-lactamase enzyme family DUF834 PF05754.14 AAAP01002164.1_1 - 0.031 14.3 1.4 0.084 12.9 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF834) CM_2 PF01817.21 AAAP01002164.1_2 - 0.00027 21.2 1.8 0.00031 21.0 1.8 1.1 1 0 0 1 1 1 1 Chorismate mutase type II ATP-grasp_3 PF02655.14 AAAP01002165.1_2 - 1.4e-09 38.2 0.0 3.5e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 AAAP01002165.1_2 - 1.7e-09 37.5 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 AAAP01002165.1_2 - 3.9e-05 23.2 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 AAAP01002165.1_2 - 9.6e-05 21.8 0.0 0.07 12.4 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 AAAP01002165.1_2 - 0.00023 20.8 0.0 0.042 13.5 0.0 2.7 1 1 1 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 AAAP01002165.1_2 - 0.01 15.4 0.0 0.97 9.0 0.0 2.1 1 1 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAAP01002165.1_2 - 0.26 10.8 0.0 2.3 7.7 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus HTH_1 PF00126.27 AAAP01002166.1_1 - 3.6e-19 68.4 0.1 3.9e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAAP01002166.1_1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAAP01002166.1_1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAAP01002166.1_1 - 0.048 13.5 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Pyr_redox_2 PF07992.14 AAAP01002166.1_2 - 8.8e-27 94.1 0.4 1e-26 93.9 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01002166.1_2 - 6e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01002166.1_2 - 2.4e-06 27.0 0.0 3.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Toprim PF01751.22 AAAP01002167.1_1 - 5.1e-06 26.7 0.0 5.7e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Toprim domain Peptidase_M56 PF05569.11 AAAP01002168.1_1 - 0.0055 16.0 3.4 0.0069 15.6 3.4 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 SH3_3 PF08239.11 AAAP01002169.1_3 - 2.7e-30 104.4 10.6 6.3e-13 48.8 0.4 3.3 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_4 PF06347.13 AAAP01002169.1_3 - 7.8e-28 96.1 7.2 6.1e-11 42.0 0.1 3.3 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_9 PF14604.6 AAAP01002169.1_3 - 7.7e-07 28.9 1.9 0.54 10.2 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 AAAP01002169.1_3 - 6.8e-06 25.7 1.0 1 9.1 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain DUF4453 PF14627.6 AAAP01002169.1_3 - 0.011 15.8 9.4 0.038 14.1 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4453) SH3_16 PF18348.1 AAAP01002169.1_3 - 0.22 11.4 1.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_6 PF12913.7 AAAP01002169.1_3 - 0.7 9.5 2.8 9.8 5.8 0.1 2.8 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) CAP_N PF01213.19 AAAP01002169.1_3 - 1.8 8.0 18.7 0.62 9.5 1.1 2.2 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AAA_30 PF13604.6 AAAP01002170.1_2 - 3e-46 157.6 0.0 6.6e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_4 PF14490.6 AAAP01002170.1_2 - 2.9e-37 126.5 0.0 2.5e-29 101.1 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix containing domain AAA_19 PF13245.6 AAAP01002170.1_2 - 3e-35 121.7 0.0 4.9e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 AAAP01002170.1_2 - 3.7e-16 59.5 0.4 1.2e-10 41.8 0.1 3.7 3 0 0 3 3 3 2 Helix-hairpin-helix domain AAA_11 PF13086.6 AAAP01002170.1_2 - 7e-09 35.8 0.8 6e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 AAAP01002170.1_2 - 1.8e-06 28.0 0.7 9.7e-06 25.5 0.7 2.0 1 1 0 1 1 1 1 Helicase HHH_2 PF12826.7 AAAP01002170.1_2 - 2.3e-06 27.6 0.2 8e-05 22.7 0.1 2.6 1 1 1 2 2 2 1 Helix-hairpin-helix motif AAA_16 PF13191.6 AAAP01002170.1_2 - 3.9e-05 24.1 0.2 0.00013 22.4 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain HHH_3 PF12836.7 AAAP01002170.1_2 - 7.8e-05 22.9 0.2 0.12 12.7 0.0 2.9 3 0 0 3 3 2 1 Helix-hairpin-helix motif T2SSE PF00437.20 AAAP01002170.1_2 - 0.0003 19.9 0.0 0.00058 19.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 AAAP01002170.1_2 - 0.00079 19.1 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 AAAP01002170.1_2 - 0.0017 17.4 0.1 0.0027 16.7 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 AAAP01002170.1_2 - 0.0034 16.6 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase HHH PF00633.23 AAAP01002170.1_2 - 0.0081 16.0 10.2 0.041 13.8 0.3 4.4 5 0 0 5 5 4 1 Helix-hairpin-helix motif Viral_helicase1 PF01443.18 AAAP01002170.1_2 - 0.012 15.3 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HTH_53 PF18606.1 AAAP01002170.1_2 - 0.024 14.3 0.1 14 5.5 0.0 3.0 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain DNA_pol_lambd_f PF10391.9 AAAP01002170.1_2 - 0.028 14.2 0.1 11 5.9 0.0 3.6 2 2 1 3 3 3 0 Fingers domain of DNA polymerase lambda MeaB PF03308.16 AAAP01002170.1_2 - 0.029 13.3 0.2 0.054 12.5 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 AAAP01002170.1_2 - 0.035 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 AAAP01002170.1_2 - 0.062 13.7 0.1 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AAAP01002170.1_2 - 0.076 12.9 1.3 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 AAAP01002170.1_2 - 0.083 12.9 0.2 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Transposase_20 PF02371.16 AAAP01002170.1_2 - 0.095 13.0 0.7 1.1e+02 3.3 0.1 3.6 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family IstB_IS21 PF01695.17 AAAP01002170.1_2 - 0.11 12.2 0.3 3.1 7.5 0.3 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 AAAP01002170.1_2 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_28 PF13521.6 AAAP01002170.1_2 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 AAAP01002170.1_2 - 0.15 10.6 0.1 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ABC_tran PF00005.27 AAAP01002170.1_2 - 0.17 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter UvrD-helicase PF00580.21 AAAP01002170.1_2 - 0.17 11.3 1.1 1.4 8.3 0.2 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Zeta_toxin PF06414.12 AAAP01002170.1_2 - 0.2 10.9 0.1 0.36 10.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF3701 PF12482.8 AAAP01002170.1_2 - 0.21 11.7 3.7 1 9.5 0.2 3.8 2 1 3 5 5 4 0 Phage integrase protein Biotin_lipoyl_2 PF13533.6 AAAP01002171.1_1 - 0.00029 20.6 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAAP01002171.1_1 - 0.051 12.8 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAAP01002171.1_1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme ACR_tran PF00873.19 AAAP01002171.1_2 - 2.6e-37 128.0 0.4 2.9e-37 127.9 0.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Bac_luciferase PF00296.20 AAAP01002172.1_1 - 0.0078 15.7 0.0 0.0089 15.5 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Transket_pyr PF02779.24 AAAP01002173.1_1 - 2.3e-39 134.9 0.1 3e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 AAAP01002173.1_1 - 1.7e-12 47.1 0.0 2.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF4336 PF14234.6 AAAP01002174.1_1 - 1.1e-08 34.7 0.0 2.3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4336) CHASE3 PF05227.13 AAAP01002174.1_1 - 0.045 13.7 0.1 0.059 13.3 0.1 1.1 1 0 0 1 1 1 0 CHASE3 domain Lactamase_B PF00753.27 AAAP01002174.1_2 - 1.1e-20 74.5 6.2 1.3e-20 74.3 5.8 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01002174.1_2 - 3.3e-07 30.0 0.0 4.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF937 PF06078.11 AAAP01002175.1_1 - 4.8e-12 46.7 14.9 4.3e-11 43.6 14.9 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF937) DUF3681 PF12442.8 AAAP01002177.1_1 - 0.031 14.7 4.6 2.4 8.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) DUF4916 PF16262.5 AAAP01002177.1_2 - 1.6e-84 281.6 0.3 1.9e-84 281.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4916) Metallophos_2 PF12850.7 AAAP01002179.1_1 - 1.5e-05 25.3 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAAP01002179.1_1 - 0.00094 19.7 0.1 0.0012 19.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_9 PF13371.6 AAAP01002180.1_1 - 0.051 13.7 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat NadA PF02445.16 AAAP01002180.1_1 - 0.096 11.8 0.1 0.1 11.7 0.1 1.0 1 0 0 1 1 1 0 Quinolinate synthetase A protein FAD_binding_2 PF00890.24 AAAP01002180.1_2 - 1.8e-62 211.8 17.9 2.1e-62 211.6 17.9 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAAP01002180.1_2 - 1.8e-09 37.6 8.5 6.1e-09 35.9 6.4 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAAP01002180.1_2 - 1.7e-07 30.8 1.3 0.012 14.9 1.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01002180.1_2 - 0.00025 21.1 0.5 0.0012 18.8 0.5 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.22 AAAP01002180.1_2 - 0.0012 18.0 1.8 1.9 7.5 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AAAP01002180.1_2 - 0.05 13.9 1.6 0.05 13.9 1.6 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AAAP01002180.1_2 - 0.58 9.1 2.4 0.54 9.2 0.7 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF58 PF01882.18 AAAP01002181.1_2 - 2.1e-17 63.1 0.1 6.5e-17 61.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF58 PP-binding PF00550.25 AAAP01002182.1_2 - 1e-28 99.4 2.0 1.5e-14 54.1 0.4 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site Condensation PF00668.20 AAAP01002182.1_2 - 0.0095 14.6 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 Condensation domain Na_H_antiport_2 PF13726.6 AAAP01002182.1_2 - 0.079 13.1 0.9 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Na+-H+ antiporter family tRNA-synt_1 PF00133.22 AAAP01002183.1_1 - 1.6e-120 403.2 0.0 4.2e-119 398.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01002183.1_1 - 9.9e-09 34.4 0.0 5.6e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AAAP01002183.1_1 - 6.6e-07 29.0 0.0 0.0002 20.9 0.0 2.1 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 RecC_C PF17946.1 AAAP01002183.1_1 - 0.075 12.8 0.0 1.1 9.0 0.0 2.2 2 1 0 2 2 2 0 RecC C-terminal domain Glyco_trans_4_4 PF13579.6 AAAP01002184.1_1 - 8.6e-20 71.8 22.6 8.6e-20 71.8 22.6 2.6 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01002184.1_1 - 1.1e-09 38.5 9.6 2.8e-09 37.2 6.2 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AAAP01002184.1_1 - 0.019 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01002184.1_1 - 0.028 14.0 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 SH3_4 PF06347.13 AAAP01002184.1_1 - 0.048 13.5 0.5 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain CoA_binding_2 PF13380.6 AAAP01002184.1_1 - 0.65 10.5 2.7 3.7 8.1 0.0 2.8 3 0 0 3 3 3 0 CoA binding domain Hexapep PF00132.24 AAAP01002184.1_2 - 5.2e-09 35.5 7.8 0.0011 18.6 0.7 4.1 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01002184.1_2 - 3.7e-05 23.4 0.9 0.26 11.1 0.1 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Glyco_trans_4_4 PF13579.6 AAAP01002184.1_3 - 6.4e-13 49.4 15.9 7.9e-13 49.1 15.9 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01002184.1_3 - 4.4e-12 46.3 3.9 5.4e-12 46.0 3.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 AAAP01002184.1_3 - 0.011 15.8 0.0 0.016 15.2 0.0 1.2 1 1 0 1 1 1 0 Glycosyl transferase 4-like Ribosom_S30AE_C PF16321.5 AAAP01002185.1_1 - 0.085 12.6 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus MobB PF03205.14 AAAP01002185.1_2 - 9.6e-34 116.1 0.0 1.4e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Peripla_BP_6 PF13458.6 AAAP01002186.1_1 - 2e-19 70.5 1.1 2.2e-19 70.3 1.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01002186.1_1 - 2.4e-06 26.8 0.2 2.6e-06 26.7 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01002186.1_1 - 6.5e-05 22.2 0.2 7.4e-05 22.0 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region LppC PF04348.13 AAAP01002186.1_1 - 0.038 12.8 0.1 0.045 12.6 0.1 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Ni_hydr_CYTB PF01292.20 AAAP01002187.1_1 - 1.4e-15 57.4 5.5 1.5e-15 57.3 5.5 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AAAP01002187.1_1 - 0.00011 22.6 3.4 0.00011 22.6 3.4 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4405) DUF1700 PF08006.11 AAAP01002187.1_1 - 0.59 9.6 6.2 0.055 13.0 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) HemY_N PF07219.13 AAAP01002187.1_1 - 5 7.4 6.9 0.41 10.9 1.3 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Oxidored_molyb PF00174.19 AAAP01002187.1_2 - 3.2e-45 153.8 0.0 5.6e-45 153.0 0.0 1.4 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain P-II PF00543.22 AAAP01002188.1_2 - 3.3e-32 111.1 0.3 3.7e-32 111.0 0.3 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Acyl_CoA_thio PF02551.15 AAAP01002188.1_3 - 1.5e-31 109.0 0.0 1.8e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioesterase 4HBT_3 PF13622.6 AAAP01002188.1_3 - 2.4e-25 90.2 0.3 2.6e-25 90.1 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily FAA_hydrolase PF01557.18 AAAP01002189.1_1 - 3.1e-72 242.8 0.0 3.6e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family adh_short PF00106.25 AAAP01002189.1_2 - 9.7e-24 83.9 0.5 1.1e-23 83.8 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002189.1_2 - 5.7e-18 65.3 0.4 6.8e-18 65.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01002189.1_2 - 6.3e-07 29.5 0.4 8.1e-07 29.1 0.4 1.1 1 0 0 1 1 1 1 KR domain Abhydrolase_3 PF07859.13 AAAP01002189.1_2 - 0.034 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PfkB PF00294.24 AAAP01002189.1_2 - 0.038 13.3 0.1 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 pfkB family carbohydrate kinase THF_DHG_CYH_C PF02882.19 AAAP01002189.1_2 - 0.046 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IlvN PF07991.12 AAAP01002189.1_2 - 0.05 13.2 0.4 0.14 11.7 0.4 1.6 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Capsule_synth PF05159.14 AAAP01002190.1_1 - 1.2e-27 97.2 0.0 4.3e-26 92.1 0.0 2.0 2 0 0 2 2 2 2 Capsule polysaccharide biosynthesis protein YscJ_FliF PF01514.17 AAAP01002191.1_1 - 5.8e-59 199.0 0.0 1.3e-58 197.9 0.0 1.6 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AAAP01002191.1_1 - 1.6e-26 93.4 7.1 5.2e-26 91.8 3.3 2.3 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal DUF4662 PF15578.6 AAAP01002191.1_1 - 0.073 12.8 1.3 0.11 12.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF4224 PF13986.6 AAAP01002191.1_1 - 0.17 11.8 0.0 0.48 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Lin-8 PF03353.15 AAAP01002191.1_1 - 0.34 10.4 4.4 0.47 10.0 4.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HATPase_c PF02518.26 AAAP01002193.1_2 - 1.8e-14 54.2 0.0 2.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01002193.1_2 - 2.7e-13 50.0 0.0 3.9e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAAP01002193.1_2 - 0.028 14.8 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Complex1_51K PF01512.17 AAAP01002194.1_2 - 2.1e-30 105.6 0.0 2.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit IMS_HHH PF11798.8 AAAP01002194.1_3 - 0.014 15.7 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 IMS family HHH motif HHH PF00633.23 AAAP01002194.1_3 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cdd1 PF11731.8 AAAP01002194.1_3 - 0.07 13.4 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity locus PAPS_reduct PF01507.19 AAAP01002195.1_2 - 1.6e-05 25.0 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.19 AAAP01002195.1_3 - 7.1e-09 35.9 0.0 8.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ADH_zinc_N_2 PF13602.6 AAAP01002196.1_1 - 2.3e-11 44.9 0.1 3.6e-11 44.3 0.1 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 AAAP01002196.1_2 - 1e-28 100.3 19.2 1.3e-28 99.9 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01002196.1_2 - 2e-06 27.0 10.8 3.3e-06 26.2 10.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter ATPase_gene1 PF09527.10 AAAP01002196.1_2 - 0.0077 16.4 2.3 0.0077 16.4 2.3 2.7 3 0 0 3 3 3 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter MFS_1_like PF12832.7 AAAP01002196.1_2 - 0.29 10.0 6.0 0.39 9.5 6.0 1.2 1 0 0 1 1 1 0 MFS_1 like family HATPase_c PF02518.26 AAAP01002197.1_1 - 5.6e-26 91.3 0.0 8.8e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01002197.1_1 - 1.7e-21 76.0 0.1 4.4e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01002197.1_1 - 0.0018 18.2 0.0 0.013 15.5 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA PF00512.25 AAAP01002198.1_1 - 5.9e-09 35.8 0.1 5.9e-09 35.8 0.1 2.4 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ATP-synt_B PF00430.18 AAAP01002198.1_1 - 0.015 15.4 12.2 0.024 14.7 12.2 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CENP-H PF05837.12 AAAP01002198.1_1 - 0.084 13.3 2.4 0.14 12.6 2.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) GvpL_GvpF PF06386.11 AAAP01002198.1_1 - 1.2 9.0 9.3 1.7 8.5 9.3 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF BPD_transp_2 PF02653.16 AAAP01002199.1_1 - 0.00096 18.4 6.0 0.0011 18.1 6.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01002199.1_2 - 2e-34 119.0 24.3 2e-34 119.0 24.3 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component EIID-AGA PF03613.14 AAAP01002199.1_2 - 0.12 11.6 8.0 0.096 11.9 5.1 2.0 1 1 1 2 2 2 0 PTS system mannose/fructose/sorbose family IID component TPR_12 PF13424.6 AAAP01002200.1_1 - 5e-05 23.5 2.2 0.16 12.3 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01002200.1_1 - 0.00025 20.9 0.6 0.35 11.1 1.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 AAAP01002200.1_1 - 0.0032 18.1 0.3 0.038 14.7 0.0 2.4 2 0 0 2 2 2 1 Sel1 repeat PGC7_Stella PF15549.6 AAAP01002200.1_1 - 0.011 15.7 0.5 0.02 14.9 0.5 1.4 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain TPR_10 PF13374.6 AAAP01002200.1_1 - 1.1 9.2 4.7 1.3 9.0 1.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat GAF_2 PF13185.6 AAAP01002201.1_1 - 2.2e-38 131.7 1.0 7.4e-22 78.1 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF PF01590.26 AAAP01002201.1_1 - 1.6e-27 96.8 0.0 4.5e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 GAF domain PAS_3 PF08447.12 AAAP01002201.1_1 - 7.2e-16 58.3 0.7 1.5e-15 57.2 0.7 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01002201.1_1 - 6.8e-09 35.7 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01002201.1_1 - 1.2e-06 28.7 0.8 1.2e-06 28.7 0.8 3.2 4 1 1 5 5 5 1 PAS fold PAS_9 PF13426.7 AAAP01002201.1_1 - 4.7e-06 26.8 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain GAF_3 PF13492.6 AAAP01002201.1_1 - 7e-06 26.4 0.0 0.076 13.4 0.0 3.4 3 0 0 3 3 3 2 GAF domain PAS_8 PF13188.7 AAAP01002201.1_1 - 0.0007 19.6 0.1 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain Anti-adapt_IraP PF10796.9 AAAP01002202.1_1 - 0.095 13.3 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein MSC PF09402.10 AAAP01002202.1_1 - 0.13 11.7 0.5 0.13 11.7 0.5 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain ABC_tran_CTD PF16326.5 AAAP01002202.1_2 - 0.09 13.0 0.0 0.25 11.6 0.0 1.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain MFS_1 PF07690.16 AAAP01002203.1_1 - 1.2e-17 63.9 27.1 1.6e-17 63.5 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01002203.1_1 - 5.9e-05 22.1 12.6 7.6e-05 21.7 12.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 AAAP01002203.1_1 - 0.0019 16.8 10.6 0.0052 15.4 7.0 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 AAAP01002203.1_1 - 0.0045 15.9 4.4 0.035 13.0 0.0 2.0 1 1 1 2 2 2 2 MFS_1 like family DUF4148 PF13663.6 AAAP01002204.1_1 - 0.05 13.8 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DUF4995 PF16386.5 AAAP01002204.1_1 - 0.058 13.4 0.0 0.063 13.3 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function Acetyltransf_6 PF13480.7 AAAP01002204.1_2 - 4.1e-26 91.8 1.7 4.1e-26 91.8 1.7 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain RecA PF00154.21 AAAP01002205.1_2 - 2e-13 50.4 0.1 2.3e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DNA_methylase PF00145.17 AAAP01002206.1_1 - 0.01 15.2 0.0 0.011 15.2 0.0 1.0 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Vsr PF03852.15 AAAP01002206.1_2 - 1.7e-25 88.6 0.1 3e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch endonuclease Vsr SEO_C PF14577.6 AAAP01002206.1_2 - 0.0069 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Sieve element occlusion C-terminus MTES_1575 PF18741.1 AAAP01002206.1_2 - 0.01 16.0 0.0 0.047 13.9 0.1 1.9 2 0 0 2 2 2 0 REase_MTES_1575 HTH_3 PF01381.22 AAAP01002206.1_3 - 9e-14 51.3 0.5 1.3e-13 50.7 0.5 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01002206.1_3 - 6.6e-09 36.0 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 AAAP01002206.1_3 - 2.2e-07 30.5 0.1 3.3e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 AAAP01002206.1_3 - 6.7e-07 29.2 0.1 9.8e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01002206.1_3 - 0.0014 18.6 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01002206.1_3 - 0.0093 16.4 0.1 0.014 15.8 0.1 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AAAP01002206.1_3 - 0.04 13.8 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 AAAP01002206.1_3 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_IclR PF09339.10 AAAP01002206.1_3 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-dskA_traR PF01258.17 AAAP01002208.1_1 - 2.9e-12 46.3 0.0 3.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger UreE_N PF02814.15 AAAP01002208.1_1 - 0.023 14.3 0.8 0.038 13.6 0.8 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Porin_2 PF02530.14 AAAP01002208.1_2 - 2.5e-08 33.6 0.0 1e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Porin subfamily SlyX PF04102.12 AAAP01002208.1_3 - 2.8e-21 75.9 0.3 3.1e-21 75.8 0.3 1.0 1 0 0 1 1 1 1 SlyX Spc29 PF17082.5 AAAP01002208.1_3 - 0.001 18.9 0.0 0.0011 18.8 0.0 1.0 1 0 0 1 1 1 1 Spindle Pole Component 29 TolA_bind_tri PF16331.5 AAAP01002208.1_3 - 0.013 15.6 1.8 0.024 14.7 1.8 1.4 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF16 PF01519.16 AAAP01002208.1_3 - 0.035 14.6 0.0 0.04 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 AAAP01002208.1_3 - 0.047 13.9 0.5 0.061 13.5 0.5 1.1 1 0 0 1 1 1 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 AAAP01002208.1_3 - 0.049 13.9 0.3 0.07 13.4 0.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain KASH_CCD PF14662.6 AAAP01002208.1_3 - 0.049 13.4 0.2 0.055 13.3 0.2 1.0 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 AAAP01002208.1_3 - 0.067 13.3 0.3 0.08 13.0 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 AAAP01002208.1_3 - 0.07 13.0 3.1 0.087 12.7 0.9 2.0 1 1 2 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 AAAP01002208.1_3 - 0.082 13.1 0.1 0.099 12.8 0.1 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Wtap PF17098.5 AAAP01002208.1_3 - 0.083 12.8 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family Peptidase_M23 PF01551.22 AAAP01002209.1_2 - 1.4e-17 63.7 0.0 3.2e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M23 Trypsin_2 PF13365.6 AAAP01002210.1_1 - 2.6e-05 25.2 0.1 2.6e-05 25.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAAP01002210.1_1 - 3.7e-05 23.7 0.0 3.7e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_S55 PF05580.12 AAAP01002210.1_1 - 0.0016 18.4 0.1 0.0018 18.3 0.1 1.0 1 0 0 1 1 1 1 SpoIVB peptidase S55 AAA_3 PF07726.11 AAAP01002211.1_2 - 3.5e-13 49.5 0.0 6.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAAP01002211.1_2 - 2.1e-10 40.3 2.0 4.2e-10 39.3 2.0 1.5 1 0 0 1 1 1 1 AAA lid domain MFS_1 PF07690.16 AAAP01002212.1_1 - 1.9e-30 106.0 16.6 2.7e-30 105.5 16.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 AAAP01002212.1_1 - 1.3e-06 27.2 5.1 1.6e-06 26.8 5.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 AAAP01002212.1_1 - 0.00015 20.8 10.2 0.00021 20.3 10.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 AAAP01002212.1_1 - 0.032 12.8 10.0 0.044 12.3 9.8 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein MFS_1_like PF12832.7 AAAP01002212.1_1 - 0.069 12.0 8.6 0.087 11.7 8.6 1.1 1 0 0 1 1 1 0 MFS_1 like family HlyD PF00529.20 AAAP01002212.1_2 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS adh_short PF00106.25 AAAP01002213.1_1 - 1e-50 171.9 0.0 1.2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002213.1_1 - 4.4e-40 137.7 0.0 5.2e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01002213.1_1 - 8.8e-09 35.5 0.0 1.5e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01002213.1_1 - 0.0033 16.9 0.0 0.021 14.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAAP01002213.1_1 - 0.025 14.0 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 1-cysPrx_C PF10417.9 AAAP01002213.1_1 - 0.14 12.1 0.0 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin ApbA PF02558.16 AAAP01002213.1_1 - 0.17 11.5 0.5 0.29 10.8 0.5 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TraW_N PF12477.8 AAAP01002214.1_1 - 1.3 9.1 4.8 2.1 8.4 4.8 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal HAD_2 PF13419.6 AAAP01002214.1_2 - 1e-32 113.7 0.0 1.2e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01002214.1_2 - 2.1e-20 73.9 2.8 2.4e-19 70.4 2.8 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01002214.1_2 - 7.8e-16 59.0 1.5 1e-15 58.6 1.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01002214.1_2 - 2.8e-10 40.1 0.5 8e-10 38.6 0.4 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAAP01002214.1_2 - 1.2e-05 25.3 0.0 0.00034 20.7 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 AAAP01002214.1_2 - 0.002 17.9 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Glyoxalase_4 PF13669.6 AAAP01002214.1_2 - 0.013 15.8 0.0 0.54 10.6 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hydrolase_3 PF08282.12 AAAP01002214.1_2 - 0.04 13.7 0.2 36 4.0 0.0 3.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AAAP01002214.1_2 - 0.23 11.3 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase DUF4255 PF14065.6 AAAP01002214.1_3 - 0.0022 17.7 0.2 0.004 16.9 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4255) Na_H_antiport_1 PF06965.12 AAAP01002216.1_2 - 2.9e-131 437.8 24.5 3.3e-131 437.6 24.5 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 TraX PF05857.11 AAAP01002216.1_2 - 0.15 12.1 10.2 0.038 14.1 5.6 2.5 3 1 0 3 3 3 0 TraX protein LUD_dom PF02589.15 AAAP01002217.1_1 - 0.085 12.6 0.1 0.3 10.8 0.1 1.7 1 1 0 2 2 2 0 LUD domain LUD_dom PF02589.15 AAAP01002217.1_2 - 2.2e-26 92.7 0.0 3.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 LUD domain Fer4_8 PF13183.6 AAAP01002217.1_2 - 4.7e-11 43.0 0.2 1.4e-10 41.4 0.2 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01002217.1_2 - 1.9e-07 31.1 0.6 0.00011 22.2 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain DUF3390 PF11870.8 AAAP01002217.1_2 - 5.6e-07 29.8 2.3 1.2e-06 28.8 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4 PF00037.27 AAAP01002217.1_2 - 7.1e-06 25.6 7.3 8.1e-05 22.3 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01002217.1_2 - 2.6e-05 24.7 3.7 9.1e-05 23.0 3.7 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01002217.1_2 - 0.00012 22.4 7.3 0.0021 18.4 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01002217.1_2 - 0.00015 21.7 4.8 0.0022 18.0 1.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01002217.1_2 - 0.00024 21.2 2.3 0.0062 16.7 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01002217.1_2 - 0.0012 18.8 10.4 0.0031 17.5 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01002217.1_2 - 0.0025 18.0 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01002217.1_2 - 0.0027 18.6 3.4 0.48 11.4 2.2 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAAP01002217.1_2 - 0.004 17.7 4.9 0.041 14.4 5.2 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01002217.1_2 - 0.0044 17.9 9.3 0.27 12.3 4.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01002217.1_2 - 0.006 16.7 3.4 0.13 12.4 0.5 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAAP01002217.1_2 - 0.028 14.2 0.8 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_13 PF13370.6 AAAP01002217.1_2 - 0.13 12.8 0.4 0.13 12.8 0.4 2.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I DUF58 PF01882.18 AAAP01002218.1_3 - 3.9e-18 65.5 0.1 6.7e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 AAA_lid_2 PF17863.1 AAAP01002218.1_4 - 9.8e-19 67.0 0.8 9.8e-19 67.0 0.8 1.6 2 0 0 2 2 2 1 AAA lid domain HapK PF11639.8 AAAP01002218.1_4 - 0.086 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 REDY-like protein HapK Acyltransferase PF01553.21 AAAP01002220.1_1 - 6.9e-25 87.2 0.0 8.6e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase AA_permease PF00324.21 AAAP01002220.1_2 - 1.7e-63 214.9 15.7 2e-63 214.7 15.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 AAAP01002220.1_2 - 5e-28 98.1 20.7 6.2e-28 97.8 20.7 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 AAAP01002220.1_2 - 0.028 13.3 0.0 0.028 13.3 0.0 2.4 3 0 0 3 3 3 0 Spore germination protein S_4TM PF18159.1 AAAP01002220.1_2 - 6.8 5.9 11.4 5.6 6.2 2.8 2.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Cation_efflux PF01545.21 AAAP01002221.1_1 - 2e-26 93.0 5.7 2.6e-26 92.6 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family Maf PF02545.14 AAAP01002221.1_2 - 5.5e-15 55.6 0.0 6e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein VirB8 PF04335.13 AAAP01002222.1_2 - 1.6e-51 175.1 6.4 1.9e-51 175.0 6.4 1.0 1 0 0 1 1 1 1 VirB8 protein DUF4633 PF15464.6 AAAP01002223.1_1 - 0.0089 16.2 0.9 0.0093 16.1 0.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4633) Glucosamine_iso PF01182.20 AAAP01002223.1_2 - 1.1e-39 136.7 0.0 1.2e-39 136.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 6PGD PF00393.19 AAAP01002223.1_3 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain DUF2252 PF10009.9 AAAP01002224.1_1 - 2.1e-67 227.9 0.0 2.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.23 AAAP01002224.1_1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family HPP PF04982.13 AAAP01002224.1_2 - 3.9e-17 62.6 7.6 3.9e-17 62.6 7.6 1.7 2 0 0 2 2 2 1 HPP family MCPsignal PF00015.21 AAAP01002227.1_1 - 2.1e-32 112.3 39.1 2e-29 102.6 25.5 3.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01002227.1_1 - 0.00068 19.8 15.4 0.03 14.6 2.7 3.9 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 AAAP01002227.1_1 - 0.00096 18.9 2.2 0.00096 18.9 2.2 2.8 2 1 0 2 2 2 1 Laminin Domain I DUF1664 PF07889.12 AAAP01002227.1_1 - 0.0014 18.7 4.6 0.5 10.4 0.2 3.3 2 2 1 3 3 3 2 Protein of unknown function (DUF1664) GldM_N PF12081.8 AAAP01002227.1_1 - 0.0061 16.7 3.3 0.099 12.7 0.2 2.9 1 1 1 3 3 3 1 GldM N-terminal domain Syntaxin PF00804.25 AAAP01002227.1_1 - 0.0083 15.8 1.8 2.6 7.7 0.1 2.4 2 0 0 2 2 2 2 Syntaxin DUF5333 PF17267.2 AAAP01002227.1_1 - 0.031 14.5 2.2 0.44 10.7 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5333) DUF3584 PF12128.8 AAAP01002227.1_1 - 0.043 11.4 3.1 0.33 8.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Lectin_N PF03954.14 AAAP01002227.1_1 - 0.066 13.0 1.7 0.42 10.4 0.1 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 AAAP01002227.1_1 - 0.4 10.7 12.3 1 9.4 1.6 3.3 2 2 1 3 3 3 0 Laminin Domain II TMP_2 PF06791.13 AAAP01002227.1_1 - 0.57 9.8 40.1 1.5 8.4 19.3 2.3 1 1 1 2 2 2 0 Prophage tail length tape measure protein DUF3450 PF11932.8 AAAP01002227.1_1 - 1.2 8.4 11.8 2.1 7.6 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 AAAP01002227.1_1 - 1.4 9.7 9.1 5.6 7.7 0.4 3.1 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Histone_HNS PF00816.21 AAAP01002227.1_1 - 5.5 7.9 12.3 4.7 8.1 1.1 3.4 2 1 1 3 3 3 0 H-NS histone family IlvC PF01450.19 AAAP01002229.1_1 - 9.2e-67 223.8 0.1 1.1e-66 223.6 0.1 1.0 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Fae PF08714.11 AAAP01002230.1_1 - 8.6e-30 103.8 0.0 9.5e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) SpoU_methylase PF00588.19 AAAP01002230.1_2 - 4.1e-24 85.4 0.0 4.9e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family IstB_IS21 PF01695.17 AAAP01002231.1_1 - 1.5e-27 96.5 0.0 1.7e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 IstB-like ATP binding protein DDE_Tnp_ISL3 PF01610.17 AAAP01002231.1_2 - 3.4e-05 23.7 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Transposase SspB PF04386.13 AAAP01002233.1_1 - 5.7e-37 127.1 0.0 6.4e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Stringent starvation protein B HTH_Crp_2 PF13545.6 AAAP01002234.1_2 - 4.1e-13 49.1 1.1 6.6e-13 48.4 1.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01002234.1_2 - 4.1e-06 26.8 0.1 9.9e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Rrf2 PF02082.20 AAAP01002234.1_2 - 0.0014 18.9 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01002234.1_2 - 0.0067 16.3 0.6 0.016 15.0 0.6 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01002234.1_2 - 0.016 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 MarR family Complex1_LYR_1 PF13232.6 AAAP01002234.1_2 - 0.15 12.7 0.8 12 6.6 0.1 3.0 2 1 1 3 3 3 0 Complex1_LYR-like Flg_bb_rod PF00460.20 AAAP01002235.1_1 - 0.0039 17.1 1.8 0.0039 17.1 1.8 2.8 3 0 0 3 3 3 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAAP01002235.1_2 - 6e-13 48.7 3.5 6e-13 48.7 3.5 1.7 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal CDP-OH_P_transf PF01066.21 AAAP01002236.1_1 - 0.0043 17.8 0.1 0.0048 17.6 0.1 1.1 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DEAD PF00270.29 AAAP01002236.1_2 - 1.1e-29 103.5 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01002236.1_2 - 0.0082 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EAL PF00563.20 AAAP01002237.1_1 - 5.4e-54 183.2 0.0 6.1e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 EAL domain E1-E2_ATPase PF00122.20 AAAP01002238.1_1 - 8.1e-53 178.6 0.5 1.7e-52 177.6 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01002238.1_1 - 1.5e-11 45.0 0.5 3.9e-11 43.6 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAAP01002238.1_1 - 3.1e-05 24.3 0.0 6.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Flg_bb_rod PF00460.20 AAAP01002239.1_1 - 2.2e-13 49.8 4.8 5.1e-13 48.6 4.8 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein DUF3726 PF12525.8 AAAP01002239.1_1 - 0.054 13.6 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) FliE PF02049.18 AAAP01002239.1_2 - 6.5e-16 58.3 0.2 9.7e-16 57.7 0.2 1.3 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE Flg_bbr_C PF06429.13 AAAP01002239.1_3 - 1.8e-10 40.8 0.2 3.1e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01002239.1_4 - 0.00048 20.0 2.3 0.0013 18.6 2.3 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein MGS PF02142.22 AAAP01002239.1_4 - 0.14 12.3 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 MGS-like domain B12-binding PF02310.19 AAAP01002240.1_1 - 1.8e-17 63.5 0.2 2.7e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 B12 binding domain SIS_2 PF13580.6 AAAP01002240.1_1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 SIS domain tRNA-synt_1b PF00579.25 AAAP01002240.1_2 - 8e-57 192.8 0.1 1.1e-56 192.3 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MFS_1 PF07690.16 AAAP01002241.1_1 - 4.4e-25 88.4 25.2 5.6e-25 88.0 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01002241.1_1 - 8.1e-06 25.0 12.1 1e-05 24.6 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 AAAP01002241.1_1 - 0.0017 17.8 22.0 0.0023 17.3 22.0 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Acyl_transf_3 PF01757.22 AAAP01002241.1_1 - 0.39 9.7 8.2 0.59 9.1 8.2 1.3 1 0 0 1 1 1 0 Acyltransferase family DUF4396 PF14342.6 AAAP01002241.1_1 - 3 8.2 12.2 3.7 7.9 10.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) tRNA-synt_1c PF00749.21 AAAP01002242.1_1 - 2.7e-16 59.4 0.0 3.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c PF00749.21 AAAP01002242.1_2 - 1.6e-45 155.4 0.0 2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Na_H_Exchanger PF00999.21 AAAP01002243.1_1 - 3.6e-44 151.1 26.0 4.1e-44 150.9 26.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Multi_Drug_Res PF00893.19 AAAP01002244.1_1 - 3.9e-13 49.9 6.7 5e-13 49.5 6.7 1.3 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAAP01002244.1_1 - 0.49 10.6 8.4 0.53 10.5 8.4 1.0 1 0 0 1 1 1 0 EamA-like transporter family ABC2_membrane_3 PF12698.7 AAAP01002245.1_1 - 0.00082 18.6 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ANTAR PF03861.14 AAAP01002246.1_2 - 4.1e-21 74.6 4.2 4.1e-21 74.6 4.2 1.8 2 0 0 2 2 2 1 ANTAR domain Response_reg PF00072.24 AAAP01002246.1_2 - 5.2e-07 29.8 0.1 9.5e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain NMT1_2 PF13379.6 AAAP01002246.1_3 - 3.8e-20 72.6 0.0 4e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01002246.1_3 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 NMT1/THI5 like Lactamase_B PF00753.27 AAAP01002247.1_1 - 1.1e-05 25.6 2.7 2.8e-05 24.2 2.7 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DZR PF12773.7 AAAP01002247.1_1 - 0.055 13.5 1.4 0.092 12.8 1.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon Lactamase_B_5 PF14597.6 AAAP01002247.1_1 - 0.067 12.7 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily FYDLN_acid PF09538.10 AAAP01002247.1_1 - 0.13 12.9 0.1 0.21 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GerE PF00196.19 AAAP01002248.1_1 - 0.00048 19.6 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_30 PF13556.6 AAAP01002248.1_1 - 0.0025 17.6 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AAAP01002248.1_1 - 0.056 13.6 0.3 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain BatA PF07584.11 AAAP01002249.1_1 - 9.2e-18 64.4 15.0 1.6e-17 63.6 15.0 1.4 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal SpoU_methylase PF00588.19 AAAP01002250.1_2 - 1.1e-33 116.4 0.0 2.3e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AAAP01002250.1_2 - 1.9e-07 31.3 0.0 3.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding MTS PF05175.14 AAAP01002251.1_1 - 3e-14 52.9 0.0 3.2e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 AAAP01002251.1_1 - 0.24 10.7 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FKBP_C PF00254.28 AAAP01002251.1_2 - 2e-21 76.1 0.0 3.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Abhydrolase_1 PF00561.20 AAAP01002251.1_3 - 3.1e-16 59.8 0.0 1.5e-13 51.0 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01002251.1_3 - 1.2e-15 57.4 0.8 2e-15 56.7 0.8 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAAP01002251.1_3 - 5.1e-14 53.4 16.6 6.6e-14 53.0 16.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AAAP01002251.1_3 - 0.01 15.4 0.0 0.038 13.6 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF5010 PF16402.5 AAAP01002251.1_3 - 0.013 14.3 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Esterase PF00756.20 AAAP01002251.1_3 - 0.028 14.0 0.2 0.041 13.5 0.2 1.2 1 0 0 1 1 1 0 Putative esterase BCD PF15461.6 AAAP01002252.1_1 - 3.1e-48 164.6 19.4 4e-48 164.2 19.4 1.1 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Bac_rhodopsin PF01036.18 AAAP01002252.1_2 - 5.2e-21 75.2 5.4 6.1e-21 75.0 5.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 AAAP01002252.1_2 - 4.2 7.0 6.6 1.1 8.9 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) PQQ PF01011.21 AAAP01002253.1_1 - 3.7e-24 83.5 10.4 2.5e-06 27.1 0.1 5.7 5 0 0 5 5 5 5 PQQ enzyme repeat PQQ_2 PF13360.6 AAAP01002253.1_1 - 7.8e-20 71.5 0.6 1.3e-17 64.2 0.2 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 AAAP01002253.1_1 - 1.5e-11 44.4 16.2 0.00049 20.5 0.1 6.1 5 1 0 5 5 5 3 PQQ-like domain PQQ PF01011.21 AAAP01002253.1_2 - 5e-14 51.5 0.6 4.4e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_3 PF13570.6 AAAP01002253.1_2 - 1.3e-10 41.4 4.7 8.6e-07 29.3 0.0 3.5 4 1 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.6 AAAP01002253.1_2 - 2.1e-08 34.1 3.5 2.7e-08 33.7 3.5 1.2 1 0 0 1 1 1 1 PQQ-like domain Methyltransf_12 PF08242.12 AAAP01002254.1_2 - 4.2e-18 65.9 0.0 7.3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002254.1_2 - 5.6e-15 55.8 0.4 6.9e-14 52.3 0.4 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002254.1_2 - 4.3e-14 52.7 0.0 5.9e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002254.1_2 - 3.9e-13 49.9 0.1 2.4e-06 28.1 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002254.1_2 - 1e-10 41.6 0.0 2.6e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01002254.1_2 - 1.2e-05 25.0 0.1 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain MetW PF07021.12 AAAP01002254.1_2 - 0.00015 21.5 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 AAAP01002254.1_2 - 0.0011 18.4 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 AAAP01002254.1_2 - 0.004 16.1 0.0 0.025 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AAAP01002254.1_2 - 0.0045 17.0 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01002254.1_2 - 0.0064 15.9 0.0 1.7 7.9 0.0 2.0 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family NodS PF05401.11 AAAP01002254.1_2 - 0.093 12.3 0.0 3.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) ADH_zinc_N PF00107.26 AAAP01002254.1_2 - 0.11 12.5 0.1 0.7 9.9 0.1 2.3 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_2 PF00891.18 AAAP01002254.1_2 - 0.18 11.1 0.6 10 5.3 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain DXP_reductoisom PF02670.16 AAAP01002254.1_3 - 6.6e-40 136.8 2.3 9.1e-40 136.4 2.3 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 AAAP01002254.1_3 - 2e-16 59.9 0.0 3.4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 AAAP01002254.1_3 - 0.072 13.5 0.1 0.2 12.1 0.1 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AAAP01002254.1_3 - 0.2 12.3 3.1 1.6 9.4 3.1 2.2 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.13 AAAP01002254.1_3 - 0.23 11.0 1.3 0.32 10.5 1.3 1.5 1 1 0 1 1 1 0 NmrA-like family ABC_tran PF00005.27 AAAP01002255.1_1 - 1e-20 74.6 0.0 3.3e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002255.1_1 - 8.2e-11 42.2 0.6 0.00021 21.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01002255.1_1 - 4.4e-05 23.0 0.0 0.083 12.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01002255.1_1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAAP01002255.1_1 - 0.007 16.1 0.2 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01002255.1_1 - 0.0081 16.4 0.1 0.047 14.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01002255.1_1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01002255.1_1 - 0.02 15.4 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01002255.1_1 - 0.048 13.8 0.0 0.082 13.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAAP01002255.1_1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01002255.1_1 - 0.087 13.2 1.3 0.22 11.9 0.5 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 AAAP01002255.1_1 - 0.087 12.4 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_S74 PF13884.6 AAAP01002256.1_1 - 8.5e-10 38.8 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Chaperone of endosialidase ACAS_N PF16177.5 AAAP01002257.1_1 - 5.8e-16 58.2 0.9 9e-16 57.5 0.9 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF465 PF04325.13 AAAP01002257.1_2 - 8.5e-12 44.9 2.9 1.1e-11 44.6 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF465) Kelch_1 PF01344.25 AAAP01002258.1_1 - 2.5e-26 91.0 1.3 1e-07 31.4 0.0 4.4 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 AAAP01002258.1_1 - 5.2e-19 67.8 0.2 0.00023 21.3 0.0 4.4 2 1 2 4 4 4 4 Kelch motif Kelch_3 PF13415.6 AAAP01002258.1_1 - 1.3e-16 60.5 12.1 9.9e-06 25.7 0.0 4.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 AAAP01002258.1_1 - 2.6e-14 52.5 0.0 0.0061 16.5 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 AAAP01002258.1_1 - 5.9e-13 48.6 0.3 7e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 AAAP01002258.1_1 - 1.1e-10 41.2 0.2 0.00026 20.9 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Amino_oxidase PF01593.24 AAAP01002258.1_2 - 4.1e-14 52.7 2.8 6.3e-14 52.1 2.8 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAAP01002258.1_2 - 1.3e-13 50.9 2.8 2.9e-13 49.9 2.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAAP01002258.1_2 - 8.4e-09 35.3 1.5 9.3e-09 35.1 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AAAP01002258.1_2 - 2e-06 27.6 2.2 2.4e-06 27.4 2.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01002258.1_2 - 8.1e-06 24.8 2.2 1.1e-05 24.4 2.2 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAAP01002258.1_2 - 1.4e-05 24.3 6.9 2e-05 23.9 6.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01002258.1_2 - 1.8e-05 24.2 0.4 2.1e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAAP01002258.1_2 - 0.00022 20.6 0.4 0.0003 20.1 0.4 1.1 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 AAAP01002258.1_2 - 0.0033 16.8 0.4 0.004 16.5 0.4 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 AAAP01002258.1_2 - 0.0048 16.0 1.2 0.0061 15.7 1.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 AAAP01002258.1_2 - 0.0064 15.6 4.1 0.008 15.3 4.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AAAP01002258.1_2 - 0.0079 15.5 2.6 0.011 15.1 2.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01002258.1_2 - 0.018 15.6 1.2 0.027 15.0 1.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01002258.1_2 - 0.12 12.4 0.3 0.15 12.0 0.3 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding MarR_2 PF12802.7 AAAP01002259.1_2 - 2.1e-05 24.3 1.9 2.6e-05 24.0 0.5 2.1 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AAAP01002259.1_2 - 0.00011 22.2 0.1 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 AAAP01002259.1_2 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAAP01002259.1_2 - 0.00019 20.9 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding ROK PF00480.20 AAAP01002259.1_2 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 ROK family HTH_IclR PF09339.10 AAAP01002259.1_2 - 0.0014 18.4 0.1 0.0042 16.8 0.1 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_28 PF13518.6 AAAP01002259.1_2 - 0.0079 16.3 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Crp PF00325.20 AAAP01002259.1_2 - 0.01 15.5 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF742 PF05331.11 AAAP01002259.1_2 - 0.017 15.0 1.2 0.24 11.2 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF742) HTH_36 PF13730.6 AAAP01002259.1_2 - 0.051 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AAAP01002259.1_2 - 0.2 11.5 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Condensation PF00668.20 AAAP01002260.1_1 - 8e-11 41.3 0.0 4.4e-08 32.2 0.0 2.0 2 0 0 2 2 2 2 Condensation domain Glyoxalase PF00903.25 AAAP01002261.1_1 - 1.1e-06 28.8 0.0 0.00078 19.6 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01002261.1_1 - 3.6e-06 27.7 3.3 0.00058 20.6 0.6 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAAP01002261.1_1 - 7.9e-06 26.1 0.0 2.2e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAAP01002261.1_1 - 0.0018 18.4 0.6 1.4 9.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain FR47 PF08445.10 AAAP01002261.1_1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein IalB PF06776.12 AAAP01002262.1_1 - 4.1e-26 91.6 0.0 5.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Invasion associated locus B (IalB) protein Voltage_CLC PF00654.20 AAAP01002263.1_1 - 6.4e-63 213.1 38.0 7.8e-63 212.9 38.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 AAAP01002263.1_1 - 3.3e-15 56.3 1.0 7.5e-08 32.7 0.1 2.3 2 0 0 2 2 2 2 CBS domain SDH_alpha PF03313.15 AAAP01002263.1_1 - 0.098 12.3 0.9 18 4.9 0.0 2.4 2 1 0 2 2 2 0 Serine dehydratase alpha chain HisKA PF00512.25 AAAP01002264.1_1 - 2.6e-07 30.6 0.2 2.6e-07 30.6 0.2 2.1 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain UPF0242 PF06785.11 AAAP01002264.1_1 - 0.52 10.4 3.9 1.5 8.9 3.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AMP-binding PF00501.28 AAAP01002264.1_2 - 1.1e-13 50.7 0.1 1.3e-13 50.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF4384 PF14326.6 AAAP01002264.1_2 - 0.06 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Response_reg PF00072.24 AAAP01002265.1_1 - 0.00032 20.8 0.0 0.00067 19.8 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Bac_export_2 PF01312.19 AAAP01002265.1_3 - 1.5e-58 198.6 0.2 1.6e-58 198.5 0.2 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family GFO_IDH_MocA PF01408.22 AAAP01002265.1_3 - 0.096 13.5 0.0 2.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold BPD_transp_1 PF00528.22 AAAP01002266.1_1 - 1.2e-14 54.5 15.7 1.2e-14 54.5 15.7 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Fer2 PF00111.27 AAAP01002267.1_1 - 9.3e-10 38.3 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01002267.1_1 - 0.0011 19.0 1.1 0.0015 18.5 1.0 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_M20 PF01546.28 AAAP01002267.1_3 - 0.00012 21.8 0.0 0.00014 21.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HPTransfase PF10090.9 AAAP01002267.1_3 - 0.084 12.7 0.1 0.096 12.5 0.1 1.1 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain FCH PF00611.23 AAAP01002268.1_1 - 0.019 15.2 1.7 3.2 8.1 0.1 3.1 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Aconitase PF00330.20 AAAP01002269.1_1 - 6.9e-131 437.4 0.0 8.2e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) ACR_tran PF00873.19 AAAP01002270.1_1 - 3.2e-65 220.5 0.3 3.7e-65 220.2 0.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family CBM_6 PF03422.15 AAAP01002271.1_1 - 1.9e-06 28.2 0.5 4.9e-06 26.9 0.5 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DSBA PF01323.20 AAAP01002272.1_1 - 0.073 12.8 0.1 0.083 12.7 0.1 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Peptidase_M1 PF01433.20 AAAP01002272.1_2 - 8.6e-13 48.4 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 AAAP01002272.1_2 - 5.8e-11 42.9 0.0 2e-10 41.2 0.0 1.8 1 1 1 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_C57 PF03290.13 AAAP01002272.1_2 - 0.15 10.7 0.2 0.2 10.3 0.2 1.1 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Ald_Xan_dh_C PF01315.22 AAAP01002273.1_1 - 6.5e-21 74.8 0.6 7.3e-21 74.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 AAAP01002273.1_2 - 1e-06 28.8 0.6 9.9e-06 25.7 0.6 2.0 1 1 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain ECH_2 PF16113.5 AAAP01002274.1_1 - 2.4e-102 342.8 0.0 2.9e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAAP01002274.1_1 - 4.1e-23 82.0 0.4 1.7e-22 80.0 0.3 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF1421 PF07223.11 AAAP01002274.1_1 - 0.054 13.3 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) FA_desaturase PF00487.24 AAAP01002274.1_2 - 0.57 10.0 10.2 0.12 12.2 6.9 1.4 1 1 1 2 2 2 0 Fatty acid desaturase TMEM43 PF07787.12 AAAP01002274.1_2 - 0.6 9.5 2.3 0.95 8.8 2.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 HTH_OrfB_IS605 PF12323.8 AAAP01002275.1_1 - 1.2e-07 31.0 0.5 2e-07 30.4 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain CNV-Replicase_N PF16688.5 AAAP01002275.1_1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 CPBP PF02517.16 AAAP01002276.1_1 - 0.004 17.5 1.2 0.0055 17.1 0.2 1.7 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Sdh_cyt PF01127.22 AAAP01002276.1_1 - 0.016 15.2 1.9 0.022 14.8 1.9 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Vps55 PF04133.14 AAAP01002276.1_2 - 0.0068 16.3 0.6 0.0083 16.1 0.6 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 5_3_exonuc_N PF02739.16 AAAP01002276.1_3 - 6.6e-16 58.6 0.0 7.4e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain tRNA_synt_2f PF02092.17 AAAP01002277.1_1 - 8.6e-104 348.4 0.1 9.9e-104 348.2 0.1 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit Ribosomal_L5 PF00281.19 AAAP01002277.1_1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L5 DoxX PF07681.12 AAAP01002278.1_2 - 0.0078 16.8 4.5 0.0078 16.8 4.5 1.6 2 0 0 2 2 2 1 DoxX DoxX_2 PF13564.6 AAAP01002278.1_2 - 0.45 10.7 8.9 0.97 9.6 7.5 2.0 1 1 1 2 2 2 0 DoxX-like family Seryl_tRNA_N PF02403.22 AAAP01002279.1_1 - 4.9e-25 87.9 3.7 7.7e-25 87.2 3.7 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PqqA PF08042.11 AAAP01002279.1_2 - 0.00015 21.6 0.9 0.00031 20.6 0.9 1.6 1 0 0 1 1 1 1 PqqA family PqqA PF08042.11 AAAP01002279.1_3 - 4.7e-09 35.9 0.6 5.8e-09 35.6 0.2 1.4 2 0 0 2 2 2 1 PqqA family AI-2E_transport PF01594.16 AAAP01002280.1_1 - 1.7e-10 40.6 0.9 2.1e-10 40.3 0.9 1.1 1 0 0 1 1 1 1 AI-2E family transporter PAS_8 PF13188.7 AAAP01002281.1_1 - 3.2e-08 33.4 0.0 0.0036 17.3 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAAP01002281.1_1 - 7.8e-08 32.6 0.0 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01002281.1_1 - 2.3e-06 27.8 0.0 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01002281.1_1 - 0.0033 17.4 0.0 0.026 14.5 0.0 2.3 2 2 0 2 2 2 1 PAS fold MFS_1 PF07690.16 AAAP01002282.1_1 - 5e-28 98.0 31.1 6.4e-28 97.7 31.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01002282.1_1 - 0.0068 15.3 12.6 0.0091 14.9 12.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 AAAP01002282.1_1 - 0.022 14.0 17.8 0.031 13.6 17.8 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB ROK PF00480.20 AAAP01002283.1_1 - 3.6e-18 66.1 0.0 4.1e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 ROK family Peripla_BP_3 PF13377.6 AAAP01002283.1_2 - 5.5e-31 108.1 0.2 6e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 AAAP01002283.1_2 - 1.4e-08 34.7 0.0 1.9e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 AAAP01002283.1_2 - 4.1e-06 26.4 0.0 4.2e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Acetyltransf_5 PF13444.6 AAAP01002283.1_2 - 0.074 13.8 0.0 0.095 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_2b PF00587.25 AAAP01002285.1_1 - 4.9e-41 140.7 0.0 4.4e-40 137.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAAP01002285.1_1 - 1.2e-17 63.8 1.2 2e-17 63.1 1.2 1.3 1 0 0 1 1 1 1 Anticodon binding domain Sugar_tr PF00083.24 AAAP01002286.1_1 - 2.2e-29 102.6 14.1 4.6e-29 101.6 14.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 AAAP01002286.1_1 - 2.3e-29 102.5 36.2 3e-29 102.0 36.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 AAAP01002286.1_1 - 0.073 11.5 11.4 0.0086 14.5 2.6 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 AAAP01002286.1_1 - 3.3 7.7 5.7 0.51 10.3 0.7 2.3 2 1 0 2 2 2 0 HCMV UL42 GGDEF PF00990.21 AAAP01002287.1_1 - 0.12 12.1 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain MitoNEET_N PF10660.9 AAAP01002288.1_1 - 0.034 14.2 0.2 0.088 12.9 0.1 1.6 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Tlr3_TMD PF17968.1 AAAP01002288.1_1 - 1.2 9.4 0.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain bMG5 PF17972.1 AAAP01002289.1_1 - 3e-31 108.4 0.1 4.8e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG5 domain bMG6 PF17962.1 AAAP01002289.1_1 - 5.4e-31 107.1 0.7 1.6e-30 105.6 0.1 2.0 2 0 0 2 2 2 1 Bacterial macroglobulin domain 6 MG3 PF17791.1 AAAP01002289.1_1 - 0.0007 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Macroglobulin domain MG3 TetR_C_24 PF17932.1 AAAP01002289.1_1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 AAAP01002290.1_1 - 1.7e-19 70.0 32.5 5.8e-19 68.2 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OEP PF02321.18 AAAP01002291.1_1 - 1.2e-05 25.2 0.2 1.4e-05 25.0 0.2 1.0 1 0 0 1 1 1 1 Outer membrane efflux protein OEP PF02321.18 AAAP01002291.1_2 - 1.5e-28 99.9 10.3 2.1e-28 99.5 10.3 1.1 1 0 0 1 1 1 1 Outer membrane efflux protein PsaN PF05479.11 AAAP01002291.1_2 - 0.08 13.1 0.3 0.21 11.8 0.3 1.7 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DHQ_synthase PF01761.20 AAAP01002292.1_1 - 6.1e-97 323.9 0.0 7.2e-97 323.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AAAP01002292.1_1 - 4e-14 52.9 0.4 4.9e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AAAP01002292.1_1 - 1.4e-13 50.5 1.0 3.2e-12 46.0 0.2 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01002292.1_1 - 0.011 15.1 0.2 0.038 13.3 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RsdA_SigD_bd PF16751.5 AAAP01002292.1_1 - 0.26 11.6 1.0 0.62 10.4 0.1 2.1 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region Metallophos PF00149.28 AAAP01002293.1_1 - 0.00042 20.9 0.0 0.0015 19.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Flavokinase PF01687.17 AAAP01002294.1_1 - 1.9e-33 115.1 0.0 2.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase FAD_syn PF06574.12 AAAP01002294.1_1 - 3.4e-28 98.5 0.0 4.9e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Sigma70_r4_2 PF08281.12 AAAP01002295.1_1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2959 PF11172.8 AAAP01002295.1_1 - 0.34 11.0 1.5 0.38 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Lactamase_B PF00753.27 AAAP01002296.1_1 - 9.4e-21 74.7 6.0 1e-20 74.6 4.9 1.6 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01002296.1_1 - 0.00011 21.8 0.4 0.00015 21.4 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Response_reg PF00072.24 AAAP01002297.1_1 - 2.5e-12 47.0 0.0 3.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAAP01002297.1_1 - 0.00037 20.1 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 FleQ PF06490.11 AAAP01002297.1_1 - 0.0088 16.4 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ ABC2_membrane_6 PF06182.11 AAAP01002297.1_1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Nitroreductase PF00881.24 AAAP01002298.1_2 - 5.1e-08 33.2 0.0 5.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MBOAT PF03062.19 AAAP01002300.1_2 - 2.4e-18 66.6 4.5 2.4e-18 66.6 4.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AAAP01002300.1_2 - 1.7e-06 28.2 1.7 2.8e-06 27.5 0.8 1.9 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Tad PF13400.6 AAAP01002301.1_1 - 3.8e-13 49.5 8.0 7.9e-13 48.5 8.0 1.5 1 0 0 1 1 1 1 Putative Flp pilus-assembly TadE/G-like TadE PF07811.12 AAAP01002301.1_1 - 0.01 16.1 2.4 0.018 15.3 0.2 2.3 2 0 0 2 2 2 0 TadE-like protein HEPN_SAV2148 PF18725.1 AAAP01002301.1_1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 SAV2148-like HEPN PAS_4 PF08448.10 AAAP01002302.1_1 - 1.5e-16 60.6 0.0 8.9e-15 54.9 0.0 2.5 2 1 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAAP01002302.1_1 - 1.9e-16 60.1 0.0 7.1e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01002302.1_1 - 2.7e-14 53.3 0.0 5e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01002302.1_1 - 2.7e-10 40.2 0.0 3e-09 36.9 0.0 2.3 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01002302.1_1 - 1.4e-08 34.6 0.0 0.00099 19.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain MEKHLA PF08670.11 AAAP01002302.1_1 - 0.0027 17.6 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 MEKHLA domain CENP-F_leu_zip PF10473.9 AAAP01002302.1_1 - 0.011 15.8 0.6 0.047 13.7 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 AAAP01002302.1_1 - 0.022 15.0 0.5 0.73 10.1 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HAD_2 PF13419.6 AAAP01002302.1_1 - 0.14 12.3 0.2 0.23 11.5 0.2 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Laminin_II PF06009.12 AAAP01002302.1_1 - 0.16 12.0 1.1 0.25 11.3 0.3 1.8 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 AAAP01002302.1_1 - 0.2 11.7 0.9 0.37 10.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Transketolase_C PF02780.20 AAAP01002303.1_1 - 7.3e-07 29.1 0.0 7.6e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 AAAP01002303.1_2 - 8.6e-77 258.3 0.0 1e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AAAP01002303.1_2 - 8.5e-39 133.1 0.0 2.4e-37 128.3 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain ABC-3 PF00950.17 AAAP01002304.1_1 - 5.5e-17 62.1 19.5 6.4e-17 61.9 19.5 1.1 1 0 0 1 1 1 1 ABC 3 transport family CstA PF02554.14 AAAP01002304.1_1 - 0.0012 17.8 14.8 0.0014 17.6 14.8 1.0 1 0 0 1 1 1 1 Carbon starvation protein CstA YitT_membrane PF02588.15 AAAP01002304.1_1 - 0.068 12.5 7.2 0.085 12.2 7.2 1.1 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Sugar_tr PF00083.24 AAAP01002304.1_1 - 0.32 9.8 10.2 0.38 9.5 10.2 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF2157 PF09925.9 AAAP01002304.1_1 - 5.4 6.8 8.4 0.74 9.6 1.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 AAAP01002304.1_1 - 9.1 5.9 7.7 34 4.0 7.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2070 PF09843.9 AAAP01002304.1_1 - 9.3 4.4 11.2 12 4.1 11.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FUR PF01475.19 AAAP01002304.1_2 - 6e-30 103.9 0.0 6.7e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 AAAP01002304.1_2 - 0.0098 15.8 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB NifU PF01106.17 AAAP01002304.1_2 - 0.12 12.5 0.2 15 5.8 0.1 2.4 2 0 0 2 2 2 0 NifU-like domain DUF1289 PF06945.13 AAAP01002304.1_2 - 1.7 8.5 6.3 17 5.3 1.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1289) SNARE_assoc PF09335.11 AAAP01002304.1_3 - 0.00053 20.5 2.7 0.00076 20.0 2.7 1.3 1 0 0 1 1 1 1 SNARE associated Golgi protein Flavi_M PF01004.19 AAAP01002304.1_3 - 0.14 11.9 0.1 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M DUF559 PF04480.12 AAAP01002306.1_1 - 5.7e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 AAAP01002306.1_1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.5 1 1 0 1 1 1 1 REase_MTES_1575 DUF2726 PF10881.8 AAAP01002306.1_1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) SDF PF00375.18 AAAP01002306.1_2 - 0.11 11.6 4.8 0.13 11.2 0.2 2.0 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family PK_C PF02887.16 AAAP01002308.1_1 - 3.7e-27 94.9 0.1 4.5e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Alpha-amylase PF00128.24 AAAP01002309.1_1 - 7.9e-16 58.5 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain His_Phos_1 PF00300.22 AAAP01002309.1_1 - 0.012 15.3 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) SCFA_trans PF02667.14 AAAP01002310.1_1 - 1.1e-40 140.0 2.5 1.3e-40 139.8 2.5 1.0 1 0 0 1 1 1 1 Short chain fatty acid transporter DUF2070 PF09843.9 AAAP01002310.1_1 - 3.7 5.7 8.6 4.8 5.4 8.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CxxCxxCC PF03692.15 AAAP01002312.1_1 - 3.3e-07 30.9 0.4 5.9e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Helicase_C PF00271.31 AAAP01002313.1_1 - 5e-20 71.9 0.0 3.1e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 AAAP01002313.1_1 - 9e-11 41.9 0.0 2.3e-10 40.5 0.0 1.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF448 PF04296.13 AAAP01002314.1_2 - 1.3e-23 82.7 0.1 2.7e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF448) HTH_3 PF01381.22 AAAP01002315.1_2 - 7.2e-09 35.6 0.1 1.2e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01002315.1_2 - 2.5e-06 27.7 0.1 4.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01002315.1_2 - 0.00023 21.1 0.1 0.00033 20.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AAAP01002315.1_2 - 0.024 14.5 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Vps5 PF09325.10 AAAP01002315.1_2 - 0.12 11.9 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like adh_short_C2 PF13561.6 AAAP01002316.1_1 - 2.3e-19 69.9 0.6 5.3e-18 65.4 0.6 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002316.1_1 - 3.7e-15 55.9 0.1 3.8e-08 33.0 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase RTX PF02382.15 AAAP01002316.1_1 - 0.12 12.1 0.8 0.16 11.6 0.8 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Orn_Arg_deC_N PF02784.16 AAAP01002317.1_1 - 6.8e-18 64.9 0.0 8.1e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain AMP-binding_C PF13193.6 AAAP01002317.1_2 - 9.3e-05 23.3 0.0 0.00011 23.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zip PF02535.22 AAAP01002318.1_1 - 4.5e-08 32.7 17.1 1e-07 31.5 9.9 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4131 PF13567.6 AAAP01002318.1_1 - 0.32 10.6 8.8 0.052 13.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF983 PF06170.12 AAAP01002319.1_1 - 3.5e-31 107.5 1.0 4.2e-31 107.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF983) DUF3483 PF11982.8 AAAP01002319.1_1 - 0.06 13.0 0.8 0.073 12.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) NUDIX PF00293.28 AAAP01002319.1_2 - 8.1e-06 25.9 0.0 2.3e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.7 AAAP01002320.1_1 - 1.3e-14 55.3 4.3 1.6e-14 55.1 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01002320.1_1 - 0.0024 17.2 0.1 0.9 8.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 AAAP01002320.1_1 - 0.011 15.6 0.2 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 Serine hydrolase Thioesterase PF00975.20 AAAP01002320.1_1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S28 PF05577.12 AAAP01002320.1_1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_M75 PF09375.10 AAAP01002321.1_2 - 0.002 17.6 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Imelysin WXG100 PF06013.12 AAAP01002321.1_2 - 0.0047 17.1 0.2 0.007 16.6 0.2 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG LptF_LptG PF03739.14 AAAP01002322.1_1 - 1.5e-63 214.9 0.3 1.7e-63 214.6 0.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF4190 PF13828.6 AAAP01002322.1_1 - 0.001 18.8 0.5 0.001 18.8 0.5 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4190) FtsX PF02687.21 AAAP01002322.1_1 - 0.12 12.9 5.9 0.64 10.5 0.0 2.5 2 0 0 2 2 2 0 FtsX-like permease family ParD_antitoxin PF03693.14 AAAP01002322.1_2 - 2.1e-05 24.8 0.1 3.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH ParD PF09386.10 AAAP01002322.1_2 - 0.036 14.5 0.4 0.26 11.7 0.1 2.0 1 1 1 2 2 2 0 Antitoxin ParD QRPTase_C PF01729.19 AAAP01002323.1_2 - 4.8e-60 202.2 1.0 6.1e-60 201.8 1.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AAAP01002323.1_2 - 2.4e-26 91.6 0.1 5e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Succ_DH_flav_C PF02910.20 AAAP01002323.1_3 - 1.7e-13 50.7 0.4 1.2e-07 31.8 0.1 2.2 1 1 1 2 2 2 2 Fumarate reductase flavoprotein C-term FAD_binding_2 PF00890.24 AAAP01002323.1_3 - 8.3e-07 28.4 0.9 5.3e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain T6SS-SciN PF12790.7 AAAP01002324.1_3 - 0.092 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 ABC_tran PF00005.27 AAAP01002325.1_1 - 5.8e-05 23.6 0.0 0.00011 22.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 AAAP01002325.1_1 - 0.00017 21.8 0.1 0.00027 21.1 0.1 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 AAAP01002325.1_1 - 0.19 11.5 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Plug PF07715.15 AAAP01002325.1_2 - 1e-23 83.9 2.2 1e-23 83.9 2.2 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain HWE_HK PF07536.14 AAAP01002326.1_1 - 5.7e-18 65.4 0.2 1.1e-17 64.5 0.2 1.5 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 AAAP01002326.1_1 - 2e-05 24.8 0.1 0.00014 22.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAAP01002326.1_1 - 0.0067 16.7 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAAP01002326.1_1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HisKA_2 PF07568.12 AAAP01002326.1_1 - 0.043 13.9 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase Autotransporter PF03797.19 AAAP01002326.1_2 - 1e-22 81.1 0.4 1.2e-22 80.8 0.4 1.1 1 0 0 1 1 1 1 Autotransporter beta-domain ETF PF01012.21 AAAP01002327.1_1 - 3.8e-35 121.4 0.5 4.4e-35 121.2 0.5 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Cob_adeno_trans PF01923.18 AAAP01002327.1_2 - 2e-38 132.1 0.0 2.2e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase GST_C_2 PF13410.6 AAAP01002327.1_2 - 0.074 13.1 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAAP01002328.1_1 - 1.7e-20 72.7 0.2 1.9e-20 72.6 0.2 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAAP01002328.1_1 - 6.5e-16 58.3 0.0 7.6e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 AAAP01002328.1_1 - 0.0038 17.3 0.0 0.005 17.0 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 AAAP01002328.1_1 - 0.03 14.4 3.2 1.3 9.1 3.2 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase RVT_3 PF13456.6 AAAP01002328.1_1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Reverse transcriptase-like APOBEC2 PF18772.1 AAAP01002328.1_1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 AAAP01002328.1_1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Na_H_antiport_1 PF06965.12 AAAP01002328.1_2 - 3e-92 309.4 11.6 3.5e-92 309.1 11.6 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 rve_3 PF13683.6 AAAP01002329.1_1 - 1.9e-31 107.6 0.0 3.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AAAP01002329.1_1 - 1.1e-25 90.1 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAAP01002329.1_1 - 0.00011 22.4 0.0 0.00013 22.2 0.0 1.1 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 AAAP01002329.1_1 - 0.0085 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Transposase_20 PF02371.16 AAAP01002329.1_2 - 3.4e-18 65.7 0.2 6.2e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAAP01002329.1_2 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Transposase HHH_5 PF14520.6 AAAP01002329.1_2 - 9.8e-05 22.9 0.3 0.03 14.9 0.0 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.23 AAAP01002329.1_2 - 0.0081 16.0 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AAAP01002329.1_2 - 0.1 13.2 0.0 0.56 10.9 0.0 2.1 2 1 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DDE_Tnp_1_2 PF13586.6 AAAP01002329.1_3 - 1e-08 35.4 0.4 1.1e-08 35.3 0.4 1.0 1 0 0 1 1 1 1 Transposase DDE domain L27_2 PF09045.10 AAAP01002329.1_3 - 0.19 11.7 0.0 0.24 11.4 0.0 1.3 1 1 0 1 1 1 0 L27_2 Amidase PF01425.21 AAAP01002330.1_1 - 6.7e-56 190.1 0.6 1.1e-55 189.5 0.6 1.3 1 1 0 1 1 1 1 Amidase OpuAC PF04069.12 AAAP01002331.1_1 - 1.1e-20 74.3 0.0 1.2e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 AAAP01002331.1_2 - 2e-08 34.2 10.1 2e-08 34.2 10.1 2.7 1 1 2 4 4 4 1 Binding-protein-dependent transport system inner membrane component TAL_effector PF03377.13 AAAP01002331.1_2 - 0.019 15.3 0.1 0.18 12.1 0.0 2.6 2 0 0 2 2 2 0 TAL effector repeat PetG PF02529.15 AAAP01002331.1_3 - 0.45 10.4 4.0 0.71 9.8 4.0 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 GWT1 PF06423.12 AAAP01002333.1_2 - 0.0016 18.6 0.2 0.2 11.8 0.1 2.4 2 0 0 2 2 2 2 GWT1 7TMR-DISM_7TM PF07695.11 AAAP01002333.1_2 - 0.0033 17.4 4.5 0.0033 17.4 4.5 2.4 2 0 0 2 2 2 1 7TM diverse intracellular signalling PfkB PF00294.24 AAAP01002334.1_1 - 0.098 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase PCSK9_C1 PF18459.1 AAAP01002334.1_1 - 0.11 12.6 0.5 4.2 7.6 0.0 2.7 2 1 1 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Metallophos PF00149.28 AAAP01002335.1_2 - 1.3e-13 51.9 0.0 2e-13 51.3 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01002335.1_2 - 1.8e-10 41.3 0.0 4.8e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ketoacyl-synt PF00109.26 AAAP01002336.1_1 - 3.1e-84 282.5 0.1 4e-84 282.1 0.1 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAAP01002336.1_1 - 1.1e-35 122.2 0.1 7.4e-35 119.5 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 AAAP01002336.1_1 - 0.00024 20.9 1.2 0.00024 20.9 1.2 2.4 2 1 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AAAP01002336.1_1 - 0.00029 20.3 0.2 0.00059 19.3 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain APH PF01636.23 AAAP01002337.1_1 - 0.002 18.1 0.1 0.0023 17.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family T2SSF PF00482.23 AAAP01002337.1_2 - 3.4e-05 23.8 0.5 5.4e-05 23.1 0.5 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Phage_holin_5_1 PF06946.11 AAAP01002337.1_3 - 0.0047 17.3 0.9 0.0054 17.1 0.9 1.0 1 0 0 1 1 1 1 Bacteriophage A118-like holin, Hol118 TPR_4 PF07721.14 AAAP01002338.1_1 - 0.025 15.1 5.0 0.025 15.1 5.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2303 PF10065.9 AAAP01002338.1_3 - 0.027 13.6 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) HMGL-like PF00682.19 AAAP01002339.1_2 - 2.9e-19 69.7 0.0 3.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 HMGL-like CoA_binding_3 PF13727.6 AAAP01002340.1_1 - 5.8e-12 46.0 0.4 8.9e-12 45.4 0.4 1.3 1 0 0 1 1 1 1 CoA-binding domain UPF0093 PF03653.13 AAAP01002341.1_1 - 1.6e-36 125.7 0.9 1.9e-36 125.5 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) CopD PF05425.13 AAAP01002341.1_1 - 5.2e-05 23.6 4.2 6.7e-05 23.2 4.2 1.1 1 0 0 1 1 1 1 Copper resistance protein D YlaC PF10777.9 AAAP01002341.1_1 - 0.16 11.8 0.5 0.23 11.3 0.5 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC LprI PF07007.12 AAAP01002341.1_2 - 0.0022 18.6 0.3 0.0034 18.0 0.3 1.3 1 1 0 1 1 1 1 Lysozyme inhibitor LprI DUF2958 PF11171.8 AAAP01002342.1_1 - 2.1e-38 131.0 0.0 2.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2958) MPTase-PolyVal PF18818.1 AAAP01002342.1_2 - 2.5e-50 169.7 0.0 3.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 AAAP01002342.1_2 - 1.1e-38 132.2 0.0 1.5e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) DUF2934 PF11154.8 AAAP01002343.1_4 - 2.2e-14 52.8 7.9 4.7e-14 51.8 7.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) DUF4813 PF16072.5 AAAP01002343.1_4 - 0.22 11.2 6.8 0.29 10.8 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) SpecificRecomb PF10136.9 AAAP01002344.1_1 - 0.0028 16.1 0.5 0.003 15.9 0.5 1.0 1 0 0 1 1 1 1 Site-specific recombinase PqiA PF04403.13 AAAP01002344.1_1 - 0.012 15.5 1.3 0.012 15.4 1.3 1.2 1 0 0 1 1 1 0 Paraquat-inducible protein A Phage_holin_5_2 PF16079.5 AAAP01002344.1_1 - 0.41 11.0 3.3 0.14 12.5 0.9 1.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Plug PF07715.15 AAAP01002344.1_2 - 1.5e-15 57.7 0.0 4.6e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Epimerase PF01370.21 AAAP01002345.1_1 - 1.2e-26 93.7 0.0 1.3e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01002345.1_1 - 1.2e-10 41.4 0.1 2.2e-10 40.5 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AAAP01002345.1_1 - 1.7e-10 41.1 0.0 2e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AAAP01002345.1_1 - 3.1e-09 36.2 0.0 3.3e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AAAP01002345.1_1 - 7.9e-06 25.6 1.0 4.6e-05 23.1 1.0 2.0 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 AAAP01002345.1_1 - 0.0016 17.6 0.5 0.055 12.6 0.5 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01002345.1_1 - 0.0046 16.2 0.0 1.7 7.8 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein Glyco_tran_WecB PF03808.13 AAAP01002345.1_2 - 8.5e-61 204.8 0.1 1.1e-60 204.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family DUF3665 PF12427.8 AAAP01002345.1_2 - 0.24 11.1 1.3 0.52 10.1 0.3 2.0 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Na_H_Exchanger PF00999.21 AAAP01002346.1_1 - 1.5e-08 33.8 7.1 1.8e-08 33.6 7.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MscS_porin PF12795.7 AAAP01002346.1_2 - 0.014 14.9 3.8 0.02 14.4 3.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Golgin_A5 PF09787.9 AAAP01002346.1_2 - 0.023 14.2 0.2 0.031 13.7 0.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 AAAP01002346.1_2 - 0.024 14.0 0.5 0.024 14.0 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) T3SSipB PF16535.5 AAAP01002346.1_2 - 0.082 13.4 4.3 0.048 14.1 2.7 1.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB GHMP_kinases_C PF08544.13 AAAP01002347.1_1 - 1.7e-08 34.7 0.4 2.1e-08 34.4 0.4 1.2 1 0 0 1 1 1 1 GHMP kinases C terminal CD20 PF04103.15 AAAP01002347.1_2 - 1.2 9.3 10.0 1.6 8.8 9.9 1.4 1 1 0 1 1 1 0 CD20-like family AXE1 PF05448.12 AAAP01002347.1_3 - 2.6e-90 302.3 0.0 3e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 AAAP01002347.1_3 - 4.2e-07 29.7 0.0 6.4e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AAAP01002347.1_3 - 0.0001 22.2 0.1 0.00014 21.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 AAAP01002347.1_3 - 0.0018 17.9 1.3 0.012 15.2 1.3 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 AAAP01002347.1_3 - 0.012 15.2 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 AAAP01002347.1_3 - 0.097 11.9 4.0 5.1 6.3 3.3 2.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 AAAP01002347.1_3 - 0.22 11.4 0.0 0.44 10.4 0.0 1.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TetR_C_3 PF08362.11 AAAP01002348.1_1 - 5.8e-39 133.3 0.0 7.8e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 AAAP01002348.1_1 - 2.5e-14 52.8 0.0 3.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAAP01002348.1_1 - 0.022 15.0 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 AAAP01002348.1_1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 AAAP01002348.1_1 - 0.6 10.9 3.4 3 8.6 1.5 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ureidogly_lyase PF04115.12 AAAP01002348.1_2 - 5.7e-46 156.6 0.0 6.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase PEP-utilizers_C PF02896.18 AAAP01002349.1_1 - 3.5e-29 101.9 0.0 5.4e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AAAP01002349.1_1 - 2e-19 69.1 1.0 5.1e-19 67.8 1.0 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PEP-utilisers_N PF05524.13 AAAP01002349.1_1 - 2.5e-19 69.5 0.0 2.5e-19 69.5 0.0 1.9 3 0 0 3 3 3 1 PEP-utilising enzyme, N-terminal Pyr_redox_2 PF07992.14 AAAP01002350.1_1 - 1.9e-09 37.2 0.0 1.9e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01002350.1_1 - 0.0039 16.3 0.1 0.0039 16.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 AAAP01002350.1_1 - 0.0047 15.8 0.1 0.0055 15.6 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 AAAP01002350.1_1 - 0.04 13.0 0.1 0.049 12.7 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 AAAP01002350.1_1 - 0.049 12.9 0.1 0.058 12.6 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 AAAP01002350.1_1 - 0.061 12.4 2.9 0.077 12.1 2.9 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 AAAP01002350.1_1 - 0.066 11.9 0.8 0.077 11.7 0.8 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 AAAP01002350.1_1 - 0.073 13.3 1.1 0.12 12.6 1.1 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAAP01002350.1_1 - 0.13 12.8 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01002350.1_1 - 0.19 11.0 0.4 0.26 10.6 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AAAP01002350.1_1 - 0.24 10.6 0.7 0.29 10.3 0.7 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LysR_substrate PF03466.20 AAAP01002350.1_2 - 2.7e-52 177.2 0.0 3.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01002350.1_2 - 2e-15 56.5 0.7 3.5e-15 55.7 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAAP01002350.1_2 - 3.9e-05 22.8 0.0 0.00013 21.1 0.0 1.9 1 1 0 1 1 1 1 PBP superfamily domain HTH_20 PF12840.7 AAAP01002350.1_2 - 0.035 14.1 0.2 0.14 12.2 0.2 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain PBP_like_2 PF12849.7 AAAP01002350.1_2 - 0.047 13.3 0.0 1.3 8.6 0.0 2.2 1 1 0 1 1 1 0 PBP superfamily domain HTH_30 PF13556.6 AAAP01002350.1_2 - 0.11 12.3 0.3 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AAAP01002350.1_2 - 0.18 11.4 0.8 1.1 8.9 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF2730 PF10805.8 AAAP01002350.1_2 - 0.24 11.5 0.1 0.44 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HGTP_anticodon PF03129.20 AAAP01002351.1_1 - 2.3e-09 37.3 2.2 3.8e-09 36.6 2.2 1.4 1 1 0 1 1 1 1 Anticodon binding domain UCR_TM PF02921.14 AAAP01002351.1_2 - 0.09 13.3 0.2 0.092 13.2 0.2 1.0 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region PALP PF00291.25 AAAP01002352.1_1 - 1.9e-63 214.6 5.5 2.1e-63 214.5 5.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme COX3 PF00510.18 AAAP01002353.1_1 - 1.3e-91 307.0 23.6 1.5e-91 306.8 23.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Glyco_hydro_38N PF01074.22 AAAP01002353.1_1 - 0.039 13.3 0.5 0.062 12.7 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain COX7B PF05392.11 AAAP01002353.1_1 - 0.14 11.8 0.2 0.14 11.8 0.2 2.6 3 0 0 3 3 3 0 Cytochrome C oxidase chain VIIB CtaG_Cox11 PF04442.14 AAAP01002353.1_2 - 8e-33 113.6 0.0 9e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF11 PF01345.18 AAAP01002353.1_2 - 7.8e-05 22.9 0.0 0.00013 22.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF11 NPCBM_assoc PF10633.9 AAAP01002353.1_2 - 0.063 13.5 0.2 0.3 11.4 0.3 1.8 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4232 PF14016.6 AAAP01002353.1_2 - 0.078 13.1 0.1 4.1 7.6 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4232) Aldedh PF00171.22 AAAP01002354.1_1 - 1.7e-68 231.3 0.2 1.9e-68 231.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DHDPS PF00701.22 AAAP01002354.1_2 - 5e-54 183.0 0.0 5.6e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_2 PF04909.14 AAAP01002354.1_2 - 0.0029 17.5 0.9 0.011 15.5 0.3 1.7 1 1 1 2 2 2 1 Amidohydrolase Hexokinase_2 PF03727.16 AAAP01002354.1_2 - 0.01 15.3 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase PEP_mutase PF13714.6 AAAP01002354.1_2 - 0.012 15.1 2.3 0.019 14.4 2.3 1.4 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase ROS_MUCR PF05443.11 AAAP01002355.1_2 - 3e-41 140.4 0.0 3.7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein FAM216B PF15107.6 AAAP01002355.1_2 - 0.14 12.0 0.0 1 9.2 0.0 2.1 2 1 0 2 2 2 0 FAM216B protein family Peripla_BP_2 PF01497.18 AAAP01002356.1_1 - 2e-25 89.8 0.0 2.6e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Oxidored_nitro PF00148.19 AAAP01002356.1_1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Abhydrolase_1 PF00561.20 AAAP01002356.1_2 - 1.4e-19 70.7 0.2 1.6e-19 70.5 0.2 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01002356.1_2 - 2.3e-09 38.2 8.0 2.8e-09 37.9 8.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01002356.1_2 - 1.2e-06 27.9 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Transp_inhibit PF18791.1 AAAP01002356.1_2 - 0.014 14.8 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain DUF4174 PF13778.6 AAAP01002357.1_3 - 1.5e-25 90.0 0.0 3.5e-25 88.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) ADH_N_2 PF16884.5 AAAP01002357.1_4 - 2.7e-43 146.3 0.0 4e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Trp_halogenase PF04820.14 AAAP01002358.1_1 - 2e-40 139.0 0.0 3.8e-40 138.1 0.0 1.3 2 0 0 2 2 2 1 Tryptophan halogenase OprB PF04966.12 AAAP01002359.1_1 - 1.2e-30 107.2 2.0 1.6e-30 106.8 2.0 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family AdoHcyase PF05221.17 AAAP01002360.1_1 - 1.5e-46 158.9 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AAAP01002360.1_1 - 9.2e-38 129.9 0.7 1.4e-37 129.3 0.7 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 AAAP01002360.1_1 - 0.0015 18.1 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AAAP01002360.1_1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAAP01002360.1_1 - 0.042 13.2 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase PF05221.17 AAAP01002360.1_2 - 6.7e-37 127.2 0.0 7.1e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AAAP01002360.1_2 - 3.2e-24 85.8 0.1 4.8e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ald_Xan_dh_C2 PF02738.18 AAAP01002361.1_1 - 6.3e-07 28.2 0.0 7.2e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase RskA PF10099.9 AAAP01002361.1_1 - 0.039 14.3 3.3 0.043 14.1 3.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA eIF-1a PF01176.19 AAAP01002361.1_1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Fer2_2 PF01799.20 AAAP01002361.1_2 - 2.3e-24 85.2 4.8 2.5e-24 85.1 0.1 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01002361.1_2 - 7.2e-07 29.1 0.5 1.9e-06 27.7 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01002361.1_2 - 4.8e-06 26.5 0.1 7.5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAAP01002361.1_2 - 0.027 14.5 2.2 0.038 14.0 1.3 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain OSK PF17182.4 AAAP01002361.1_2 - 0.15 11.2 0.4 1.8 7.8 0.1 2.0 2 0 0 2 2 2 0 OSK domain Glycos_transf_3 PF00591.21 AAAP01002362.1_1 - 3.5e-73 246.3 0.0 4.3e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain IGPS PF00218.21 AAAP01002362.1_2 - 1.7e-05 24.2 0.0 1.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase CobT PF06213.12 AAAP01002362.1_2 - 0.067 12.6 0.4 0.083 12.3 0.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Oxidored_FMN PF00724.20 AAAP01002363.1_1 - 1.7e-53 182.1 0.0 2.2e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.19 AAAP01002363.1_1 - 0.015 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain IspA PF04279.15 AAAP01002364.1_1 - 7.5e-60 202.1 10.1 8.6e-60 201.9 10.1 1.0 1 0 0 1 1 1 1 Intracellular septation protein A DUF3093 PF11292.8 AAAP01002364.1_1 - 2.7 8.2 6.2 0.29 11.4 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DUF2721 PF11026.8 AAAP01002364.1_1 - 5.1 7.0 10.2 8.3 6.3 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SRP54 PF00448.22 AAAP01002364.1_2 - 8e-71 237.7 0.1 9e-71 237.6 0.1 1.0 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AAAP01002364.1_2 - 4.5e-06 26.1 0.0 6.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AAAP01002364.1_2 - 6.5e-05 22.7 0.4 9.6e-05 22.2 0.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAAP01002364.1_2 - 0.00019 21.9 0.1 0.00035 21.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AAAP01002364.1_2 - 0.0071 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 AAAP01002364.1_2 - 0.0086 16.4 0.1 0.02 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 AAAP01002364.1_2 - 0.0094 15.0 1.1 0.033 13.2 1.1 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AAAP01002364.1_2 - 0.016 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AAAP01002364.1_2 - 0.018 14.7 0.2 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 Thymidylate kinase cobW PF02492.19 AAAP01002364.1_2 - 0.023 14.3 0.5 0.064 12.8 0.5 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AAAP01002364.1_2 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AAAP01002364.1_2 - 0.036 13.9 0.3 0.61 9.8 0.4 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 AAAP01002364.1_2 - 0.047 14.1 0.1 0.097 13.1 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 AAAP01002364.1_2 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family VirC1 PF07015.11 AAAP01002364.1_2 - 0.11 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein NTPase_1 PF03266.15 AAAP01002364.1_2 - 0.11 12.3 1.3 3.7 7.4 0.7 2.2 1 1 1 2 2 2 0 NTPase CbiA PF01656.23 AAAP01002364.1_2 - 0.12 12.4 1.2 7.3 6.7 0.4 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AIG1 PF04548.16 AAAP01002364.1_2 - 0.13 11.5 0.4 0.71 9.2 0.0 1.9 2 0 0 2 2 2 0 AIG1 family UDG PF03167.19 AAAP01002365.1_1 - 1.3e-09 38.2 0.1 1.6e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ILVD_EDD PF00920.21 AAAP01002365.1_2 - 2.4e-81 273.9 0.4 2.9e-81 273.7 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family DUF4154 PF13689.6 AAAP01002365.1_2 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 YfiR/HmsC-like MurJ PF03023.14 AAAP01002366.1_1 - 3.1e-81 273.3 24.2 3.8e-81 273.0 24.2 1.0 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt PF01943.17 AAAP01002366.1_1 - 2.2e-08 33.8 7.2 2.2e-08 33.8 7.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AAAP01002366.1_1 - 3.1e-08 33.8 16.6 3.1e-08 33.8 16.6 3.2 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 AAAP01002366.1_1 - 6.9e-06 25.8 11.1 6.9e-06 25.8 11.1 3.7 3 2 1 4 4 4 2 MatE Aminotran_4 PF01063.19 AAAP01002367.1_1 - 4.4e-35 121.6 0.0 5.2e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV GST_N PF02798.20 AAAP01002367.1_1 - 0.047 14.0 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PepSY_2 PF13670.6 AAAP01002367.1_2 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CPBP PF02517.16 AAAP01002368.1_1 - 4.5e-10 39.8 8.1 3.7e-08 33.6 0.3 2.2 2 0 0 2 2 2 2 CPBP intramembrane metalloprotease Yip1 PF04893.17 AAAP01002368.1_1 - 0.014 15.1 7.2 0.014 15.1 7.2 2.0 1 1 0 2 2 2 0 Yip1 domain ATG27 PF09451.10 AAAP01002368.1_1 - 0.4 10.5 0.7 0.57 10.0 0.7 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 HTH_5 PF01022.20 AAAP01002368.1_2 - 5.7e-15 54.9 0.0 8.5e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01002368.1_2 - 1.1e-10 41.4 1.7 1.1e-10 41.4 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 AAAP01002368.1_2 - 8.4e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01002368.1_2 - 0.00017 21.4 1.0 0.001 18.9 0.1 2.2 1 1 1 2 2 2 1 MarR family HTH_24 PF13412.6 AAAP01002368.1_2 - 0.0017 17.8 0.0 0.0048 16.4 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 AAAP01002368.1_2 - 0.004 17.3 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 PaaX-like protein RP-C PF03428.13 AAAP01002368.1_2 - 0.017 14.8 0.1 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 Replication protein C N-terminal domain Penicillinase_R PF03965.16 AAAP01002368.1_2 - 0.022 15.1 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor TrmB PF01978.19 AAAP01002368.1_2 - 0.041 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 AAAP01002368.1_2 - 0.085 12.7 1.1 0.21 11.4 0.2 2.2 2 1 0 2 2 2 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01002368.1_2 - 0.094 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4423 PF14394.6 AAAP01002368.1_2 - 0.099 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) RepL PF05732.11 AAAP01002368.1_2 - 0.21 11.0 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) DAO PF01266.24 AAAP01002368.1_3 - 1.5e-09 37.9 6.2 7.5e-09 35.6 1.5 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01002368.1_3 - 6e-08 32.2 6.8 1.4e-05 24.4 2.6 2.0 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 AAAP01002368.1_3 - 2.4e-07 30.3 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01002368.1_3 - 3.9e-07 30.2 1.2 7e-07 29.4 0.5 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAAP01002368.1_3 - 4.4e-05 22.4 0.4 6.2e-05 21.9 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 AAAP01002368.1_3 - 7.6e-05 22.1 1.4 7.6e-05 22.1 1.4 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AAAP01002368.1_3 - 8.3e-05 21.8 2.9 0.003 16.7 0.5 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 AAAP01002368.1_3 - 0.00011 21.5 0.1 0.00016 21.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 AAAP01002368.1_3 - 0.00018 20.9 2.8 0.00037 19.9 1.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 AAAP01002368.1_3 - 0.00054 19.3 1.1 0.0014 17.9 1.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01002368.1_3 - 0.0021 18.6 0.6 0.005 17.4 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAAP01002368.1_3 - 0.0043 16.5 6.6 0.015 14.7 6.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAAP01002368.1_3 - 0.027 14.5 1.7 0.11 12.5 0.6 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 AAAP01002368.1_3 - 0.061 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 AAAP01002368.1_3 - 0.079 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 AAAP01002368.1_3 - 0.14 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 AAAP01002368.1_3 - 0.24 10.4 4.7 0.12 11.4 2.5 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAAP01002368.1_3 - 0.3 10.4 1.1 0.5 9.6 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 AAAP01002369.1_1 - 5.5e-09 36.6 0.0 9.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002369.1_1 - 0.00054 20.7 0.0 0.00078 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002369.1_1 - 0.00062 19.6 0.0 0.00073 19.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01002369.1_1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AAAP01002369.1_1 - 0.0024 18.5 0.0 0.0036 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002369.1_1 - 0.0097 15.7 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AAAP01002369.1_1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase SIS_2 PF13580.6 AAAP01002370.1_2 - 8.3e-27 93.9 0.3 1.1e-26 93.5 0.3 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AAAP01002370.1_2 - 2.7e-07 30.5 0.2 6.6e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 SIS domain Glycos_transf_2 PF00535.26 AAAP01002371.1_1 - 9.3e-14 51.6 0.0 2.1e-13 50.4 0.0 1.7 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01002371.1_1 - 2.4e-13 50.5 0.7 4.3e-13 49.7 0.7 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01002371.1_1 - 2.5e-07 30.8 0.7 4.8e-07 29.9 0.7 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 AAAP01002371.1_1 - 7.5e-07 28.9 0.0 0.0065 16.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 AAAP01002371.1_1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 AAAP01002371.1_1 - 0.014 14.9 0.2 0.032 13.7 0.2 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 AAAP01002371.1_1 - 0.032 13.9 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase like family HEPN_AbiV PF18728.1 AAAP01002371.1_1 - 2.1 8.5 3.4 1.2 9.3 0.7 1.8 2 0 0 2 2 2 0 AbiV Phage_tail_X PF05489.12 AAAP01002372.1_3 - 0.026 14.2 0.8 0.44 10.2 0.0 3.1 3 0 0 3 3 3 0 Phage Tail Protein X Glu_syn_central PF04898.14 AAAP01002373.1_1 - 3e-117 391.1 0.0 4e-117 390.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GATase_2 PF00310.21 AAAP01002373.1_1 - 3.9e-79 266.3 0.0 5e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ACR_tran PF00873.19 AAAP01002374.1_1 - 1.7e-40 138.6 10.5 1.9e-40 138.4 10.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01002374.1_1 - 0.014 14.3 10.6 0.017 14.1 10.6 1.1 1 0 0 1 1 1 0 MMPL family Cation_efflux PF01545.21 AAAP01002374.1_1 - 0.019 14.7 1.3 0.024 14.4 1.3 1.1 1 0 0 1 1 1 0 Cation efflux family DUF2975 PF11188.8 AAAP01002374.1_1 - 0.2 11.6 3.8 0.33 10.8 3.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF983 PF06170.12 AAAP01002374.1_1 - 6.6 7.2 6.7 1.4 9.4 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) HEPN_Cthe2314 PF18730.1 AAAP01002375.1_1 - 0.01 15.9 0.5 0.023 14.8 0.5 1.6 1 1 0 1 1 1 0 Cthe_2314-like HEPN HEPN_RiboL-PSP PF18735.1 AAAP01002375.1_1 - 0.13 12.2 5.2 0.13 12.2 3.1 1.9 2 0 0 2 2 2 0 RiboL-PSP-HEPN Phage_integrase PF00589.22 AAAP01002376.1_1 - 0.0015 18.3 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family HTH_17 PF12728.7 AAAP01002376.1_2 - 8.6e-06 25.8 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_AlpA PF05930.12 AAAP01002376.1_2 - 1.1e-05 25.1 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) MerR PF00376.23 AAAP01002376.1_2 - 0.0098 15.6 0.0 0.036 13.8 0.1 1.8 2 0 0 2 2 2 1 MerR family regulatory protein HTH_24 PF13412.6 AAAP01002376.1_2 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 AAAP01002376.1_2 - 0.099 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AAAP01002376.1_2 - 0.12 11.8 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Beta_elim_lyase PF01212.21 AAAP01002377.1_1 - 0.042 13.1 0.1 0.043 13.1 0.1 1.0 1 0 0 1 1 1 0 Beta-eliminating lyase FCD PF07729.12 AAAP01002377.1_2 - 6e-24 84.9 12.0 6e-24 84.9 12.0 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AAAP01002377.1_2 - 2.8e-17 62.1 0.4 7.3e-17 60.8 0.4 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAAP01002377.1_2 - 0.0016 17.9 0.5 0.031 13.8 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAAP01002377.1_2 - 0.014 15.4 0.0 0.05 13.6 0.0 2.0 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 AAAP01002377.1_2 - 0.036 14.2 2.5 0.18 11.9 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HSP90 PF00183.18 AAAP01002379.1_1 - 1.6e-10 40.6 0.0 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Hsp90 protein S1 PF00575.23 AAAP01002381.1_1 - 6.6e-32 109.7 9.3 1.4e-19 70.2 1.2 2.2 2 0 0 2 2 2 2 S1 RNA binding domain EXOSC1 PF10447.9 AAAP01002381.1_1 - 0.014 16.0 0.6 0.29 11.8 0.0 2.5 2 1 1 3 3 3 0 Exosome component EXOSC1/CSL4 TRAM_2 PF18693.1 AAAP01002381.1_1 - 0.11 12.7 1.2 17 5.7 0.0 3.0 3 0 0 3 3 3 0 TRAM domain RNase_II_C_S1 PF18614.1 AAAP01002381.1_1 - 0.15 12.0 6.0 6.7 6.7 0.1 3.4 3 1 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain DUF3603 PF12227.8 AAAP01002381.1_2 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) 2-oxoacid_dh PF00198.23 AAAP01002382.1_1 - 1.6e-45 155.4 0.2 1.9e-45 155.2 0.2 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF1731 PF08338.11 AAAP01002382.1_2 - 4.4e-14 52.0 0.0 9.5e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 AAAP01002382.1_2 - 4.8e-08 32.8 0.0 1.1e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01002382.1_2 - 0.00025 21.0 2.5 0.00095 19.1 0.5 2.6 2 1 0 2 2 2 1 NAD(P)H-binding GATase_4 PF13230.6 AAAP01002382.1_2 - 0.0093 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RmlD_sub_bind PF04321.17 AAAP01002382.1_2 - 0.084 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 AAAP01002382.1_2 - 0.084 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family NIR_SIR_ferr PF03460.17 AAAP01002383.1_1 - 5.4e-08 32.6 0.1 1.2e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 AAAP01002383.1_1 - 3.5e-06 26.6 0.0 5.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain DUF4031 PF13223.6 AAAP01002383.1_1 - 0.069 13.4 1.1 0.099 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) GFO_IDH_MocA PF01408.22 AAAP01002384.1_1 - 6.6e-20 72.1 0.4 9.8e-20 71.6 0.4 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 AAAP01002384.1_1 - 2.7e-07 31.3 1.4 4.5e-07 30.5 1.4 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 AAAP01002384.1_1 - 2.5e-06 27.5 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 AAAP01002384.1_1 - 2.8e-05 24.6 0.1 5.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 AAAP01002384.1_1 - 0.00017 21.7 0.1 0.00028 21.0 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 AAAP01002384.1_1 - 0.0012 19.3 0.5 0.0046 17.4 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AAAP01002384.1_1 - 0.0022 17.9 3.5 0.0038 17.1 3.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding CoA_binding_2 PF13380.6 AAAP01002384.1_1 - 0.0075 16.8 0.4 0.11 13.0 0.4 2.4 2 0 0 2 2 2 1 CoA binding domain Shikimate_DH PF01488.20 AAAP01002384.1_1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AAAP01002384.1_1 - 0.012 15.9 1.4 0.042 14.1 1.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 AAAP01002384.1_1 - 0.034 14.8 0.1 0.078 13.7 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain TraT PF05818.12 AAAP01002385.1_2 - 0.34 10.6 1.7 0.39 10.4 1.7 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Phage_int_SAM_5 PF13102.6 AAAP01002386.1_1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain Aldo_ket_red PF00248.21 AAAP01002387.1_1 - 3.7e-13 49.3 0.0 4.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_15 PF00723.21 AAAP01002388.1_1 - 3.6e-13 49.1 0.1 5.1e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ABC_tran PF00005.27 AAAP01002390.1_1 - 2.8e-11 44.1 0.0 3.4e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01002390.1_1 - 4e-05 23.3 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01002390.1_1 - 6.7e-05 22.8 0.1 6.7e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01002390.1_1 - 0.00013 22.3 0.1 0.00014 22.3 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01002390.1_1 - 0.00018 21.8 0.1 0.00022 21.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01002390.1_1 - 0.00037 20.7 0.1 0.00042 20.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01002390.1_1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01002390.1_1 - 0.0017 18.9 0.0 0.0021 18.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAAP01002390.1_1 - 0.0019 17.3 0.1 0.0019 17.3 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 AAAP01002390.1_1 - 0.0025 17.6 0.1 0.0029 17.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01002390.1_1 - 0.0042 16.5 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 AAAP01002390.1_1 - 0.0061 16.5 0.1 0.0061 16.5 0.1 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 AAAP01002390.1_1 - 0.0076 16.8 0.1 0.0095 16.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01002390.1_1 - 0.0092 15.6 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 AAAP01002390.1_1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AAAP01002390.1_1 - 0.014 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 AAAP01002390.1_1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 AAAP01002390.1_1 - 0.017 15.0 0.3 0.02 14.8 0.3 1.1 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AAAP01002390.1_1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 AAAP01002390.1_1 - 0.022 14.5 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 AAAP01002390.1_1 - 0.028 14.3 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 AAAP01002390.1_1 - 0.036 14.0 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 AAAP01002390.1_1 - 0.043 13.5 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01002390.1_1 - 0.047 14.0 0.1 0.055 13.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01002390.1_1 - 0.066 13.6 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 AAAP01002390.1_1 - 0.071 12.6 0.1 0.077 12.5 0.1 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3987 PF13148.6 AAAP01002390.1_1 - 0.078 12.0 0.0 0.09 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 AAAP01002390.1_1 - 0.08 12.1 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Guanylate_kin PF00625.21 AAAP01002390.1_1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Guanylate kinase ATP_bind_1 PF03029.17 AAAP01002390.1_1 - 0.11 12.2 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 AAAP01002390.1_1 - 0.11 12.7 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 AAAP01002390.1_1 - 0.11 11.5 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 AAAP01002390.1_1 - 0.12 11.7 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family SMC_N PF02463.19 AAAP01002390.1_1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Septin PF00735.18 AAAP01002390.1_1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Septin PRK PF00485.18 AAAP01002390.1_1 - 0.2 11.3 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 AAAP01002390.1_1 - 0.22 10.6 0.0 0.23 10.6 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit BPD_transp_1 PF00528.22 AAAP01002390.1_2 - 7.1e-19 68.3 15.5 8.6e-19 68.0 15.5 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAAP01002390.1_3 - 1.6e-17 63.8 14.6 2.2e-17 63.4 14.6 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Bmp PF02608.14 AAAP01002391.1_1 - 4.7e-32 111.2 0.0 5.6e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Zeta_toxin PF06414.12 AAAP01002391.1_1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Flagellin_C PF00700.21 AAAP01002392.1_1 - 3.6e-10 40.1 0.9 3.9e-10 40.0 0.9 1.0 1 0 0 1 1 1 1 Bacterial flagellin C-terminal helical region Ten1_2 PF15490.6 AAAP01002392.1_1 - 0.083 12.6 0.0 0.083 12.6 0.0 1.0 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Trans_reg_C PF00486.28 AAAP01002392.1_2 - 1.5e-14 53.9 0.0 2.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01002392.1_2 - 0.017 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain HTH_11 PF08279.12 AAAP01002392.1_2 - 0.018 14.9 0.2 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 HTH domain Trigger_C PF05698.14 AAAP01002392.1_2 - 0.051 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus CBM_6 PF03422.15 AAAP01002393.1_1 - 6.2e-20 71.8 0.8 6.2e-20 71.8 0.8 1.9 2 1 0 2 2 2 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 AAAP01002393.1_1 - 0.00092 19.3 0.1 0.0023 18.1 0.0 1.7 2 0 0 2 2 2 1 DUF5010 C-terminal domain NMT1 PF09084.11 AAAP01002394.1_2 - 1.1e-30 107.2 0.0 1.6e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAAP01002394.1_2 - 0.068 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Acetyltransf_1 PF00583.25 AAAP01002395.1_1 - 2.1e-08 34.4 0.1 2.6e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01002395.1_1 - 1.1e-07 32.2 0.0 1.5e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01002395.1_1 - 0.00045 20.2 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01002395.1_1 - 0.0069 16.3 0.1 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAAP01002395.1_1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SSF PF00474.17 AAAP01002396.1_1 - 1.5e-11 43.9 0.2 2e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SPC12 PF06645.13 AAAP01002396.1_1 - 0.041 14.0 2.7 0.077 13.1 0.1 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3341 PF11821.8 AAAP01002396.1_1 - 0.052 13.2 1.3 0.07 12.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) ATPase_gene1 PF09527.10 AAAP01002396.1_1 - 0.064 13.4 8.0 1.6 9.0 3.2 2.6 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CPP1-like PF11833.8 AAAP01002396.1_1 - 2.9 7.5 5.3 3.8 7.1 5.3 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DRTGG PF07085.12 AAAP01002396.1_2 - 0.021 14.6 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 DRTGG domain PATR PF12951.7 AAAP01002397.1_1 - 5.7e-16 58.3 27.6 2.7e-09 36.9 8.6 4.7 5 1 0 5 5 5 3 Passenger-associated-transport-repeat OstA PF03968.14 AAAP01002397.1_1 - 0.043 14.0 0.4 0.27 11.5 0.4 2.2 1 1 0 1 1 1 0 OstA-like protein PAP2 PF01569.21 AAAP01002397.1_2 - 0.00018 21.3 0.1 0.0004 20.2 0.0 1.6 1 1 1 2 2 2 1 PAP2 superfamily DUF1428 PF07237.11 AAAP01002397.1_2 - 0.018 15.3 0.2 0.026 14.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) 4HBT PF03061.22 AAAP01002398.1_1 - 1.4e-12 47.8 0.3 1.9e-12 47.4 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAAP01002398.1_1 - 1.6e-05 25.3 0.1 2.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1285 PF06938.11 AAAP01002398.1_2 - 1e-54 184.6 0.0 1.2e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1285) RCDG1 PF15725.5 AAAP01002398.1_2 - 0.018 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Response_reg PF00072.24 AAAP01002399.1_1 - 7.3e-08 32.6 0.0 9.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Polyketide_cyc2 PF10604.9 AAAP01002399.1_2 - 6.7e-32 110.7 0.1 7.5e-32 110.6 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ACR_tran PF00873.19 AAAP01002399.1_3 - 4.6e-72 243.1 11.1 5.7e-72 242.8 11.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01002399.1_3 - 1.8e-06 27.2 12.0 2.3e-06 26.8 12.0 1.1 1 0 0 1 1 1 1 MMPL family SecD_SecF PF02355.16 AAAP01002399.1_3 - 0.0038 16.6 2.5 0.0052 16.2 2.5 1.2 1 0 0 1 1 1 1 Protein export membrane protein Response_reg PF00072.24 AAAP01002400.1_2 - 3.5e-28 98.0 0.0 9.1e-28 96.7 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AAAP01002400.1_2 - 4e-12 45.5 0.0 5.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 AAAP01002400.1_2 - 0.0014 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4_2 PF08281.12 AAAP01002400.1_2 - 0.0036 17.0 0.2 0.0063 16.2 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01002400.1_2 - 0.0095 15.7 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AAAP01002400.1_2 - 0.15 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PNP_UDP_1 PF01048.20 AAAP01002401.1_1 - 1.1e-09 37.9 1.4 2.1e-08 33.7 1.4 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily YkuD PF03734.14 AAAP01002402.1_1 - 4.8e-18 66.0 0.0 7.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF2171 PF09939.9 AAAP01002402.1_3 - 9.6e-13 48.2 1.4 1.1e-12 48.0 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2171) FtsX PF02687.21 AAAP01002403.1_1 - 1.3e-06 28.8 0.7 1.3e-06 28.8 0.7 2.3 2 1 0 2 2 2 1 FtsX-like permease family FA_desaturase PF00487.24 AAAP01002403.1_1 - 9.1 6.0 10.5 1.5 8.6 6.6 1.6 1 1 1 2 2 2 0 Fatty acid desaturase rve_2 PF13333.6 AAAP01002404.1_1 - 1.6e-05 25.0 0.0 2.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01002404.1_1 - 0.014 15.2 0.2 0.02 14.6 0.2 1.3 1 0 0 1 1 1 0 Integrase core domain DUF1007 PF06226.13 AAAP01002404.1_1 - 0.044 13.8 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Methyltransf_2 PF00891.18 AAAP01002404.1_2 - 0.03 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GSCFA PF08885.11 AAAP01002405.1_1 - 3e-28 99.1 0.0 3.7e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 GSCFA family WcbI PF18588.1 AAAP01002405.1_2 - 1.2e-41 142.6 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis enzyme WcbI PG_binding_1 PF01471.18 AAAP01002406.1_1 - 9.9e-16 57.7 0.7 1.6e-15 57.0 0.7 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain YkuD PF03734.14 AAAP01002406.1_1 - 7.2e-06 26.5 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_3 PF09374.10 AAAP01002406.1_1 - 0.00027 21.2 2.5 0.21 11.8 0.2 2.3 1 1 1 2 2 2 2 Predicted Peptidoglycan domain PRCC PF10253.9 AAAP01002406.1_1 - 0.0022 18.8 3.8 0.003 18.4 3.8 1.3 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting PG_binding_2 PF08823.11 AAAP01002406.1_1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain MLTD_N PF06474.12 AAAP01002406.1_1 - 0.015 15.5 2.0 0.036 14.3 2.0 1.7 1 0 0 1 1 1 0 MltD lipid attachment motif FAP PF07174.11 AAAP01002406.1_1 - 8.1 5.8 41.2 15 4.9 41.2 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GntR PF00392.21 AAAP01002406.1_2 - 1.6e-15 56.4 1.2 2.8e-15 55.7 1.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AAAP01002406.1_2 - 5.5e-09 35.6 0.0 8.6e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01002406.1_2 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAAP01002406.1_2 - 0.00011 22.0 1.4 0.00011 22.0 1.4 2.0 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AAAP01002406.1_2 - 0.00069 19.5 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 AAAP01002406.1_2 - 0.00079 19.2 0.7 0.057 13.3 0.1 3.0 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 AAAP01002406.1_2 - 0.0011 19.1 2.6 0.0094 16.1 0.6 2.9 2 2 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 AAAP01002406.1_2 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 AAAP01002406.1_2 - 0.017 15.2 1.0 0.057 13.5 0.3 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01002406.1_2 - 0.019 14.8 0.4 0.05 13.4 0.4 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01002406.1_2 - 0.023 14.1 0.2 0.38 10.2 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AAAP01002406.1_2 - 0.037 14.1 0.4 0.14 12.2 0.1 2.1 1 1 1 2 2 2 0 Winged helix-turn helix Rrf2 PF02082.20 AAAP01002406.1_2 - 0.065 13.6 0.0 0.15 12.4 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator HTH_36 PF13730.6 AAAP01002406.1_2 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NepR PF18557.1 AAAP01002407.1_1 - 9.8e-18 63.5 0.4 1.3e-17 63.1 0.4 1.2 1 0 0 1 1 1 1 Anti-sigma factor NepR DUF1328 PF07043.13 AAAP01002407.1_2 - 2.4e-14 53.3 17.1 2.4e-14 53.3 17.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1328) Cation_ATPase_C PF00689.21 AAAP01002407.1_2 - 0.063 13.0 2.4 0.063 13.0 2.4 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus SLATT_3 PF18184.1 AAAP01002407.1_2 - 1.5 8.9 3.2 1.6 8.9 3.2 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Phage_holin_3_6 PF07332.11 AAAP01002407.1_2 - 3.1 7.8 15.2 3.3 7.8 15.2 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4175 PF13779.6 AAAP01002407.1_2 - 3.3 5.5 5.2 3.7 5.4 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2721 PF11026.8 AAAP01002407.1_2 - 3.8 7.4 10.1 4.4 7.2 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2981 PF11200.8 AAAP01002407.1_2 - 6.2 6.5 6.9 6.9 6.3 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) EpuA PF11772.8 AAAP01002407.1_2 - 8 6.2 10.0 0.77 9.5 1.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Lactamase_B PF00753.27 AAAP01002407.1_4 - 5.6e-08 33.0 0.7 6.1e-08 32.9 0.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01002407.1_4 - 2.2e-06 27.3 0.5 2.4e-06 27.2 0.5 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ACR_tran PF00873.19 AAAP01002409.1_1 - 1.2e-90 304.6 5.3 1.5e-90 304.3 5.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAAP01002409.1_1 - 0.00046 19.6 10.7 0.00091 18.7 10.7 1.4 1 0 0 1 1 1 1 Protein export membrane protein Surface_Ag_2 PF01617.17 AAAP01002409.1_1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Surface antigen IncD PF17628.2 AAAP01002409.1_1 - 0.4 10.5 3.6 1.3 8.8 3.6 1.8 1 0 0 1 1 1 0 Inclusion membrane protein D MMPL PF03176.15 AAAP01002409.1_1 - 1.7 7.5 23.5 0.058 12.3 17.0 1.7 2 1 0 2 2 2 0 MMPL family DUF4181 PF13789.6 AAAP01002409.1_1 - 3.4 8.0 5.8 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) YbaB_DNA_bd PF02575.16 AAAP01002410.1_1 - 5e-33 113.2 6.2 5.7e-33 113.0 6.2 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family SIMPL PF04402.14 AAAP01002410.1_1 - 0.071 13.6 3.6 0.15 12.5 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF541) DUF3236 PF11576.8 AAAP01002410.1_1 - 0.073 12.8 0.2 0.12 12.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3236) DNA_pol3_gamma3 PF12169.8 AAAP01002410.1_2 - 2e-53 180.1 0.7 2e-53 180.1 0.7 1.9 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III DUF3646 PF12362.8 AAAP01002410.1_2 - 4.9e-32 110.6 1.8 1.1e-31 109.5 0.8 2.0 2 0 0 2 2 2 1 DNA polymerase III gamma and tau subunits C terminal DNA_pol3_delta2 PF13177.6 AAAP01002410.1_2 - 8.7e-05 22.4 0.2 0.00016 21.5 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 AAAP01002410.1_2 - 0.008 16.5 0.4 0.017 15.5 0.4 1.6 1 0 0 1 1 1 1 AAA C-terminal domain Sdh_cyt PF01127.22 AAAP01002411.1_1 - 0.032 14.3 0.6 0.036 14.1 0.6 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CYTH PF01928.21 AAAP01002411.1_2 - 1.1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 CYTH domain BKACE PF05853.12 AAAP01002412.1_1 - 9.7e-40 136.6 0.1 1.1e-39 136.4 0.1 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme PdxJ PF03740.13 AAAP01002412.1_1 - 0.0031 16.7 0.2 0.0041 16.3 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ NodZ PF05830.11 AAAP01002412.1_1 - 0.044 12.6 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Ribosomal_S11 PF00411.19 AAAP01002412.1_1 - 0.33 11.4 2.0 0.71 10.3 2.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S11 Sigma54_activat PF00158.26 AAAP01002412.1_2 - 2.6e-36 124.9 0.1 3.4e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01002412.1_2 - 1.1e-11 45.0 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01002412.1_2 - 1.8e-10 40.4 0.6 3.6e-10 39.5 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAAP01002412.1_2 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_1 PF00126.27 AAAP01002412.1_2 - 0.0037 17.2 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAAP01002412.1_2 - 0.0053 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAAP01002412.1_2 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 AAAP01002412.1_2 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.7 AAAP01002412.1_2 - 0.011 15.7 0.2 0.034 14.2 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Mg_chelatase PF01078.21 AAAP01002412.1_2 - 0.041 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HTH_psq PF05225.16 AAAP01002412.1_2 - 0.12 12.1 0.2 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_24 PF13412.6 AAAP01002412.1_2 - 0.26 10.9 1.5 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FtsX PF02687.21 AAAP01002413.1_1 - 5.5e-08 33.2 4.5 5.5e-08 33.2 4.5 2.1 1 1 1 2 2 2 1 FtsX-like permease family CHB_HEX_C_1 PF13290.6 AAAP01002414.1_1 - 8.8e-15 54.5 14.9 0.0012 18.9 0.2 5.8 5 0 0 5 5 5 5 Chitobiase/beta-hexosaminidase C-terminal domain Big_7 PF17957.1 AAAP01002414.1_1 - 7.1e-12 45.9 46.7 0.078 13.8 3.1 8.5 4 3 3 7 7 7 5 Bacterial Ig domain Big_6 PF17936.1 AAAP01002414.1_1 - 2.5e-07 30.9 30.8 0.21 11.9 1.2 6.6 4 2 1 5 5 5 4 Bacterial Ig domain Big_3_2 PF12245.8 AAAP01002414.1_1 - 2.7e-07 30.9 15.2 0.46 10.8 0.1 8.5 4 4 5 9 9 9 2 Bacterial Ig-like domain Big_3_4 PF13754.6 AAAP01002414.1_1 - 1.6e-05 24.6 12.1 0.0044 16.7 0.1 5.4 5 0 0 5 5 5 1 Domain of unknown function DUF5011 PF16403.5 AAAP01002414.1_1 - 1.7e-05 24.9 15.7 0.8 9.9 0.1 6.2 6 0 0 6 6 6 2 Domain of unknown function (DUF5011) HYR PF02494.16 AAAP01002414.1_1 - 0.00021 21.6 24.0 1.6 9.1 0.1 7.9 7 1 1 8 8 8 3 HYR domain Big_3_3 PF13750.6 AAAP01002414.1_1 - 0.0037 16.9 14.1 0.82 9.3 0.2 5.5 6 1 0 6 6 6 2 Bacterial Ig-like domain (group 3) KorB_C PF06613.11 AAAP01002414.1_1 - 0.22 11.5 4.0 12 6.0 0.0 4.3 4 0 0 4 4 4 0 KorB C-terminal beta-barrel domain DUF4875 PF16175.5 AAAP01002414.1_1 - 0.99 9.5 4.8 13 5.9 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4875) WWE PF02825.20 AAAP01002414.1_1 - 1.5 9.5 3.5 65 4.2 0.0 4.1 5 0 0 5 5 5 0 WWE domain Chlorovi_GP_rpt PF06598.11 AAAP01002414.1_1 - 1.6 8.8 6.1 62 3.8 0.0 5.0 5 0 0 5 5 5 0 Chlorovirus glycoprotein repeat PKD PF00801.20 AAAP01002414.1_1 - 2.4 8.1 32.1 1.1 9.2 0.3 7.5 6 3 1 7 7 7 0 PKD domain DNA_pol3_delta2 PF13177.6 AAAP01002415.1_1 - 0.00015 21.6 0.3 0.00022 21.0 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit tRNA-synt_1g PF09334.11 AAAP01002415.1_2 - 3.8e-43 147.7 0.0 4.4e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAAP01002415.1_2 - 1.1e-10 40.4 0.0 1.4e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AAAP01002415.1_2 - 1.5e-08 34.4 0.0 1.8e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GBP_C PF02841.14 AAAP01002415.1_2 - 0.12 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RibD_C PF01872.17 AAAP01002416.1_1 - 1.2e-19 71.0 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAAP01002416.1_1 - 5.1e-16 58.4 0.0 7.3e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAAP01002416.1_1 - 3.3e-07 30.2 0.0 4.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 AAAP01002416.1_1 - 0.0057 16.5 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase ATP-cone PF03477.16 AAAP01002416.1_2 - 1.4e-17 64.0 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 ATP cone domain DYW_deaminase PF14432.6 AAAP01002416.1_2 - 0.11 12.4 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases LysM PF01476.20 AAAP01002417.1_1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain CBS PF00571.28 AAAP01002417.1_1 - 0.074 13.5 0.1 0.16 12.4 0.0 1.5 2 0 0 2 2 2 0 CBS domain Phage_integrase PF00589.22 AAAP01002418.1_1 - 4.2e-11 42.9 0.0 6.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family NGP1NT PF08153.12 AAAP01002418.1_1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 NGP1NT (NUC091) domain Phage_integr_3 PF16795.5 AAAP01002418.1_1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal phage integrase DEDD_Tnp_IS110 PF01548.17 AAAP01002418.1_2 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 1 0 1 1 1 1 Transposase Isochorismatase PF00857.20 AAAP01002419.1_2 - 1.3e-32 113.4 0.0 1.5e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Aminotran_4 PF01063.19 AAAP01002419.1_3 - 3.1e-47 161.3 0.0 3.7e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV GATase PF00117.28 AAAP01002419.1_4 - 2.1e-13 50.5 0.1 2.3e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01002419.1_4 - 0.0011 18.8 0.1 0.0012 18.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C26 HTH_Tnp_1 PF01527.20 AAAP01002420.1_1 - 1.1e-15 57.7 0.2 1.5e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Transposase TnpB_IS66 PF05717.13 AAAP01002420.1_2 - 1.3e-10 41.1 0.0 1.4e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DUF4344 PF14247.6 AAAP01002421.1_1 - 1.6e-70 237.2 0.0 1.8e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Putative metallopeptidase Glycos_transf_2 PF00535.26 AAAP01002422.1_1 - 1.9e-09 37.6 0.0 9.3e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01002422.1_1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cupin_2 PF07883.11 AAAP01002422.1_2 - 1.4e-07 31.1 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AAAP01002422.1_2 - 5.7e-05 22.9 0.1 6.3e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 AAAP01002422.1_2 - 0.0031 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 AAAP01002422.1_2 - 0.0088 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Ppnp PF06865.11 AAAP01002422.1_2 - 0.16 12.4 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase Cupin_8 PF13621.6 AAAP01002422.1_2 - 0.21 11.3 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain PAS_3 PF08447.12 AAAP01002423.1_1 - 3.2e-15 56.2 0.0 4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01002423.1_1 - 5.7e-10 39.4 0.2 6.7e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01002423.1_1 - 2.9e-06 27.3 0.0 3.5e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01002423.1_1 - 4e-06 27.0 0.0 4.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01002423.1_1 - 0.00038 20.4 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 PAS domain HATPase_c PF02518.26 AAAP01002424.1_1 - 0.013 16.0 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lactamase_B PF00753.27 AAAP01002424.1_2 - 3.8e-32 111.9 8.7 4.9e-32 111.5 8.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01002424.1_2 - 1.6e-07 31.1 0.2 2.3e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAAP01002424.1_2 - 0.066 13.1 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain 4HBT PF03061.22 AAAP01002424.1_3 - 2.5e-05 24.5 0.7 4.6e-05 23.7 0.6 1.6 1 1 0 1 1 1 1 Thioesterase superfamily Guanylate_cyc PF00211.20 AAAP01002426.1_1 - 9.7e-18 64.4 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF_2 PF13185.6 AAAP01002426.1_1 - 0.0074 16.6 0.3 0.023 15.0 0.0 2.0 2 1 1 3 3 3 1 GAF domain DAO PF01266.24 AAAP01002426.1_2 - 2.3e-21 76.8 0.6 2.7e-21 76.6 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01002426.1_2 - 1.8e-07 31.3 0.6 4e-07 30.2 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01002426.1_2 - 2.7e-07 30.0 5.8 2.7e-07 30.0 5.8 1.5 1 1 1 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 AAAP01002426.1_2 - 4.8e-06 26.1 1.5 6.2e-06 25.7 1.5 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AAAP01002426.1_2 - 3.9e-05 23.0 0.2 4.9e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 AAAP01002426.1_2 - 0.0001 21.7 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAAP01002426.1_2 - 0.00012 22.0 0.8 0.00015 21.7 0.8 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AAAP01002426.1_2 - 0.00015 21.4 1.4 0.00021 20.9 1.4 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 AAAP01002426.1_2 - 0.00047 19.5 0.6 0.00062 19.1 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01002426.1_2 - 0.00081 19.9 1.1 0.0013 19.3 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAAP01002426.1_2 - 0.0018 17.4 0.7 0.0023 17.0 0.7 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 AAAP01002426.1_2 - 0.0023 17.4 0.3 0.0023 17.4 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 AAAP01002426.1_2 - 0.0035 17.9 0.2 0.0049 17.4 0.2 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 AAAP01002426.1_2 - 0.0049 16.5 0.3 0.0065 16.1 0.3 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 AAAP01002426.1_2 - 0.011 15.7 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 AAAP01002426.1_2 - 0.018 13.7 1.6 0.022 13.5 1.6 1.1 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 AAAP01002426.1_2 - 0.022 15.0 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAAP01002426.1_2 - 0.023 14.0 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 AAAP01002426.1_2 - 0.027 13.8 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_2 PF03446.15 AAAP01002426.1_2 - 0.029 14.5 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 AAAP01002426.1_2 - 0.05 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 AAAP01002426.1_2 - 0.057 12.5 2.3 0.071 12.2 2.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAAP01002426.1_2 - 0.13 12.7 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 AAAP01002426.1_2 - 0.21 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GFO_IDH_MocA PF01408.22 AAAP01002428.1_1 - 3.6e-20 73.0 0.0 4.7e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1421 PF07223.11 AAAP01002428.1_2 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain (DUF1421) DAO PF01266.24 AAAP01002429.1_1 - 4.3e-19 69.3 0.5 4.8e-19 69.2 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF3225 PF11533.8 AAAP01002430.1_1 - 4.1e-39 133.2 0.2 4.6e-39 133.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL_3 PF13474.6 AAAP01002430.1_1 - 8.2e-06 26.1 0.1 9.3e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAAP01002430.1_1 - 0.00036 20.9 0.9 0.00043 20.6 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 AAAP01002430.1_1 - 0.0039 17.8 0.0 0.0047 17.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 AAAP01002430.1_1 - 0.0047 17.5 1.3 0.0063 17.1 1.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 AAAP01002430.1_1 - 0.0055 16.8 0.1 0.0066 16.6 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 AAAP01002430.1_1 - 0.022 15.4 0.1 0.027 15.1 0.1 1.1 1 0 0 1 1 1 0 Putative lumazine-binding Amidase PF01425.21 AAAP01002430.1_2 - 2.6e-64 217.9 0.1 3.4e-64 217.5 0.1 1.1 1 0 0 1 1 1 1 Amidase Beta-lactamase PF00144.24 AAAP01002431.1_1 - 5.3e-21 75.2 0.1 6e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase 2Fe-2S_thioredx PF01257.19 AAAP01002431.1_2 - 5.8e-07 29.5 0.0 6.1e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4175 PF13779.6 AAAP01002432.1_1 - 1.1e-28 99.7 13.7 1.2e-28 99.5 13.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TSKS PF15358.6 AAAP01002432.1_1 - 0.025 13.0 0.8 0.026 12.9 0.8 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate HIG_1_N PF04588.13 AAAP01002432.1_2 - 4.8e-13 49.1 7.4 5.6e-13 48.9 7.4 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CopD PF05425.13 AAAP01002432.1_2 - 0.14 12.6 7.7 0.15 12.5 7.7 1.1 1 0 0 1 1 1 0 Copper resistance protein D Hydantoinase_B PF02538.14 AAAP01002432.1_3 - 1.5e-43 149.0 0.2 1.8e-43 148.7 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase HTH_21 PF13276.6 AAAP01002433.1_1 - 0.057 13.6 0.1 0.059 13.5 0.1 1.1 1 0 0 1 1 1 0 HTH-like domain HTH_Tnp_1 PF01527.20 AAAP01002433.1_3 - 1.9e-08 34.5 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AAAP01002433.1_3 - 2.9e-05 24.0 0.1 0.0004 20.3 0.0 2.0 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01002433.1_3 - 7.7e-05 22.4 0.1 0.00055 19.7 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01002433.1_3 - 0.00062 19.9 0.0 0.062 13.4 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01002433.1_3 - 0.057 13.5 0.0 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 AAAP01002433.1_3 - 0.12 12.7 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain Phage_X PF05155.15 AAAP01002433.1_3 - 0.14 12.6 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage X family HisKA_2 PF07568.12 AAAP01002433.1_4 - 1.5e-15 57.0 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 AAAP01002433.1_4 - 6.9e-09 36.2 0.0 1.9e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01002433.1_4 - 1.3e-07 31.6 0.0 2.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HWE_HK PF07536.14 AAAP01002433.1_4 - 0.0075 16.9 0.1 0.039 14.7 0.0 2.1 2 0 0 2 2 2 1 HWE histidine kinase HATPase_c_3 PF13589.6 AAAP01002433.1_4 - 0.06 13.2 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PhzC-PhzF PF02567.16 AAAP01002434.1_1 - 4e-24 85.6 0.0 4.5e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein NUDIX PF00293.28 AAAP01002434.1_2 - 0.0036 17.4 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Autotransporter PF03797.19 AAAP01002435.1_1 - 2.7e-13 50.1 8.3 2.7e-13 50.1 8.3 2.5 3 0 0 3 3 3 1 Autotransporter beta-domain DHDPS PF00701.22 AAAP01002436.1_1 - 7.5e-31 106.9 0.0 8.2e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TilS PF09179.11 AAAP01002436.1_1 - 0.099 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 TilS substrate binding domain FCD PF07729.12 AAAP01002436.1_2 - 2.8e-22 79.5 9.5 4.3e-22 78.9 9.5 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01002436.1_2 - 2.4e-06 27.1 0.1 5.4e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 AAAP01002436.1_2 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain SAICAR_synt PF01259.18 AAAP01002437.1_2 - 6.5e-100 333.9 0.0 7.6e-100 333.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Fasciclin PF02469.22 AAAP01002438.1_1 - 1.1e-20 74.1 0.1 1.5e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Fasciclin domain adh_short PF00106.25 AAAP01002438.1_2 - 2.8e-17 62.8 0.0 3.5e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002438.1_2 - 2.6e-11 43.5 0.9 3.2e-11 43.2 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01002438.1_2 - 0.00011 22.2 0.6 0.00014 21.8 0.6 1.1 1 0 0 1 1 1 1 KR domain FAD-oxidase_C PF02913.19 AAAP01002439.1_1 - 0.0099 15.5 0.4 0.015 14.9 0.1 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain Oxidored_q2 PF00420.24 AAAP01002439.1_2 - 0.053 13.2 1.2 0.05 13.2 1.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L VPDSG-CTERM PF18205.1 AAAP01002439.1_2 - 0.06 13.2 2.6 0.06 13.2 2.6 2.3 2 1 0 2 2 2 0 VPDSG-CTERM motif DUF3426 PF11906.8 AAAP01002439.1_3 - 0.059 13.5 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) PsbJ PF01788.17 AAAP01002439.1_4 - 2.4 8.1 8.9 0.76 9.7 1.0 2.5 3 0 0 3 3 3 0 PsbJ DAO PF01266.24 AAAP01002439.1_5 - 1.5e-16 61.0 0.1 1.7e-16 60.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01002439.1_5 - 0.00059 19.0 0.6 0.00063 18.9 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01002439.1_5 - 0.002 17.4 0.1 0.0021 17.3 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AAAP01002439.1_5 - 0.0059 16.5 0.0 0.0062 16.4 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 AAAP01002439.1_5 - 0.0066 15.8 1.5 0.0081 15.5 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01002439.1_5 - 0.0078 16.4 1.7 0.0089 16.2 1.7 1.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AAAP01002439.1_5 - 0.021 13.9 0.5 0.023 13.8 0.5 1.0 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 AAAP01002439.1_5 - 0.031 13.0 0.2 0.032 12.9 0.2 1.0 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 AAAP01002439.1_5 - 0.044 12.8 0.2 0.045 12.8 0.2 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N PF00107.26 AAAP01002440.1_1 - 1.4e-15 57.4 0.1 2.6e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01002440.1_1 - 4.7e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 AAAP01002440.1_1 - 0.066 12.7 0.4 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 AAAP01002440.1_1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAAP01002440.1_1 - 0.27 10.8 0.2 0.37 10.3 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family FliP PF00813.20 AAAP01002441.1_1 - 2.7e-76 255.7 11.2 3.2e-76 255.5 11.2 1.0 1 0 0 1 1 1 1 FliP family Guanylate_cyc PF00211.20 AAAP01002441.1_2 - 9.2e-10 38.4 0.0 1.2e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peptidase_S9 PF00326.21 AAAP01002442.1_1 - 5.5e-13 48.9 0.0 2.4e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 AAAP01002442.1_1 - 4.3e-12 46.3 0.1 4e-11 43.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 AAAP01002442.1_1 - 0.00041 20.0 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 AAAP01002442.1_1 - 0.018 14.6 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 AAAP01002442.1_1 - 0.035 13.6 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.11 AAAP01002442.1_1 - 0.048 13.6 0.0 6.9 6.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 AAAP01002442.1_1 - 0.082 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family RgpF PF05045.12 AAAP01002443.1_1 - 2.1e-43 148.9 0.0 2.5e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Rhamnan synthesis protein F zf-CCHC_2 PF13696.6 AAAP01002443.1_1 - 0.035 13.9 0.1 0.086 12.7 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle GDPD PF03009.17 AAAP01002444.1_1 - 8.9e-25 87.9 0.0 1.3e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1080 PF06439.11 AAAP01002444.1_1 - 7.7e-07 29.4 0.0 1.9e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1080) PI-PLC-X PF00388.19 AAAP01002444.1_1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Flavi_DEAD PF07652.14 AAAP01002445.1_1 - 0.12 12.4 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Flavivirus DEAD domain ATP-grasp_5 PF13549.6 AAAP01002445.1_2 - 8.2e-63 211.8 0.6 9.8e-63 211.6 0.6 1.1 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAAP01002445.1_2 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 AAAP01002445.1_2 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain DUF4147 PF13660.6 AAAP01002446.1_1 - 1.6e-60 204.5 2.2 1.7e-60 204.4 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) FGase PF05013.12 AAAP01002446.1_2 - 1.1e-24 87.8 0.0 1.3e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase DUF1244 PF06844.11 AAAP01002446.1_3 - 2.1e-38 130.3 0.2 2.7e-38 129.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1244) Terminase_4 PF05119.12 AAAP01002446.1_3 - 0.063 13.7 0.0 0.081 13.4 0.0 1.3 1 1 0 1 1 1 0 Phage terminase, small subunit ATP-grasp PF02222.22 AAAP01002447.1_2 - 6.7e-34 116.9 0.0 8.4e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AAAP01002447.1_2 - 6.5e-17 61.0 0.0 1.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain TfoX_C PF04994.13 AAAP01002447.1_2 - 0.071 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TfoX C-terminal domain GCV_H PF01597.19 AAAP01002448.1_1 - 2.8e-25 88.6 0.0 3.4e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 AAAP01002448.1_1 - 0.0046 16.7 0.1 0.0063 16.3 0.1 1.3 1 1 0 1 1 1 1 Biotin-requiring enzyme GCV_T PF01571.21 AAAP01002448.1_2 - 8.6e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AAAP01002448.1_2 - 2.7e-20 72.1 0.4 5.1e-20 71.2 0.4 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CysG_dimeriser PF10414.9 AAAP01002449.1_1 - 0.026 14.2 0.2 0.026 14.2 0.2 2.7 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region DUF892 PF05974.12 AAAP01002449.1_1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Hint_2 PF13403.6 AAAP01002449.1_2 - 1.3e-28 100.1 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Hint domain NAR PF16251.5 AAAP01002449.1_2 - 0.063 14.0 0.0 0.14 12.9 0.0 1.5 2 0 0 2 2 2 0 Nucleic acid-binding domain (NAR) Helicase_C_4 PF13871.6 AAAP01002450.1_1 - 1.1e-71 241.7 0.0 1.4e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue Secretin PF00263.21 AAAP01002451.1_2 - 5.3e-37 127.1 0.0 9.7e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein T2SS-T3SS_pil_N PF13629.6 AAAP01002451.1_2 - 3.8e-20 71.4 0.2 7.9e-20 70.4 0.2 1.6 1 0 0 1 1 1 1 Pilus formation protein N terminal region BON PF04972.17 AAAP01002451.1_2 - 5.6e-05 23.4 1.0 0.00012 22.4 0.2 1.9 2 0 0 2 2 2 1 BON domain FtsQ PF03799.15 AAAP01002452.1_1 - 4.9e-12 46.7 0.1 5.2e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Cell division protein FtsQ POTRA_1 PF08478.10 AAAP01002452.1_1 - 7.9e-08 32.5 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 POTRA domain, FtsQ-type DUF5345 PF17280.2 AAAP01002452.1_1 - 0.043 13.8 0.4 0.092 12.7 0.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) SLT PF01464.20 AAAP01002453.1_1 - 5.2e-07 29.3 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 AAAP01002453.1_1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain Acetyltransf_5 PF13444.6 AAAP01002454.1_2 - 1.7e-33 115.3 0.1 2.8e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GCV_T PF01571.21 AAAP01002455.1_3 - 5.2e-32 111.2 0.0 7.1e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Acyl_transf_1 PF00698.21 AAAP01002456.1_1 - 4.7e-22 78.9 0.0 1.2e-21 77.5 0.0 1.6 1 1 0 1 1 1 1 Acyl transferase domain PAS_8 PF13188.7 AAAP01002456.1_1 - 0.11 12.5 0.1 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 PAS domain LON_substr_bdg PF02190.16 AAAP01002457.1_1 - 3.2e-36 125.2 1.7 3.2e-36 125.2 1.7 1.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain DUF3208 PF11482.8 AAAP01002457.1_1 - 0.13 12.6 0.4 0.57 10.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3208) AvrM-A PF18241.1 AAAP01002457.1_1 - 0.7 10.3 6.9 7.5 6.9 1.2 2.2 1 1 1 2 2 2 0 Flax-rust effector AvrM-A Ost4 PF10215.9 AAAP01002458.1_1 - 0.086 12.7 0.6 0.086 12.7 0.6 2.1 2 0 0 2 2 2 0 Oligosaccaryltransferase CN_hydrolase PF00795.22 AAAP01002459.1_1 - 5.5e-09 35.7 0.0 7.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 AAAP01002459.1_1 - 0.0059 15.8 0.0 0.0083 15.3 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Rieske PF00355.26 AAAP01002460.1_2 - 4.3e-21 74.6 0.0 7e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAAP01002460.1_2 - 3.3e-06 27.0 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Transposase_mut PF00872.18 AAAP01002461.1_1 - 6e-07 28.6 0.0 7.1e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family PMT_2 PF13231.6 AAAP01002461.1_2 - 0.018 15.2 0.4 0.02 15.1 0.4 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4519 PF15012.6 AAAP01002461.1_2 - 0.64 10.2 3.1 0.66 10.2 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) HSP20 PF00011.21 AAAP01002461.1_3 - 4e-23 81.5 0.3 4.6e-23 81.3 0.3 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01002461.1_3 - 5.7e-14 51.4 0.1 9.5e-14 50.7 0.1 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 AAAP01002461.1_3 - 0.0014 19.6 0.1 0.17 13.0 0.2 2.1 1 1 1 2 2 2 1 CS domain PIH1_CS PF18201.1 AAAP01002461.1_3 - 0.0043 17.4 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain FKBP26_C PF18046.1 AAAP01002461.1_3 - 0.0045 17.1 0.8 0.43 10.7 0.0 2.3 2 0 0 2 2 2 1 FKBP26_C-terminal DUF2807 PF10988.8 AAAP01002461.1_3 - 0.0086 15.9 0.6 0.036 13.9 0.2 1.8 2 0 0 2 2 2 1 Putative auto-transporter adhesin, head GIN domain HMA PF00403.26 AAAP01002461.1_3 - 0.07 13.6 0.2 1.4 9.4 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain FecCD PF01032.18 AAAP01002462.1_1 - 1.2e-61 208.4 23.6 1.4e-61 208.2 23.6 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AAAP01002462.1_1 - 2.7e-05 23.8 11.3 3.2e-05 23.5 11.3 1.1 1 0 0 1 1 1 1 ABC 3 transport family Gly-zipper_YMGG PF13441.6 AAAP01002462.1_1 - 2 8.2 13.5 1.9 8.3 1.8 3.2 2 1 0 2 2 2 0 YMGG-like Gly-zipper ABC_tran PF00005.27 AAAP01002462.1_2 - 7.2e-30 104.3 0.0 9.6e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002462.1_2 - 1.4e-14 54.7 0.2 1.7e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01002462.1_2 - 5.2e-05 22.8 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01002462.1_2 - 0.0098 16.3 0.3 0.016 15.6 0.3 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01002462.1_2 - 0.0098 16.2 0.0 0.9 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AAAP01002462.1_2 - 0.017 14.5 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 AAAP01002462.1_2 - 0.026 14.3 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 AAAP01002462.1_2 - 0.11 12.1 0.0 11 5.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AAAP01002462.1_2 - 0.12 12.9 0.5 0.17 12.4 0.5 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01002462.1_2 - 0.15 12.1 0.5 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ALF PF03752.13 AAAP01002462.1_2 - 4.6 7.3 8.4 0.48 10.4 2.1 2.7 3 0 0 3 3 3 0 Short repeats of unknown function TPR_2 PF07719.17 AAAP01002463.1_1 - 5.8e-05 22.9 0.8 0.47 10.7 0.2 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Sel1 PF08238.12 AAAP01002464.1_1 - 4.3e-16 59.0 20.6 1.9e-06 28.3 0.8 5.6 5 1 0 5 5 5 3 Sel1 repeat NPV_P10 PF05531.12 AAAP01002464.1_1 - 0.0062 17.0 0.3 5.6 7.5 0.0 3.4 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 AAAP01002464.1_1 - 1.3 9.1 4.6 1 9.4 0.4 2.5 2 0 0 2 2 2 0 FlxA-like protein Apolipoprotein PF01442.18 AAAP01002464.1_1 - 2.5 8.0 15.7 64 3.3 15.7 2.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Sigma70_r2 PF04542.14 AAAP01002465.1_1 - 4.5e-20 71.2 0.3 7.3e-20 70.5 0.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 UCR_14kD PF02271.16 AAAP01002465.1_1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit CarD_CdnL_TRCF PF02559.16 AAAP01002465.1_2 - 3.9e-05 24.3 1.4 0.00043 20.9 0.1 2.1 2 0 0 2 2 2 1 CarD-like/TRCF domain CDC24_OB3 PF17244.2 AAAP01002465.1_2 - 0.13 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Peripla_BP_5 PF13433.6 AAAP01002466.1_1 - 1.2e-82 277.9 0.2 1.4e-82 277.6 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAAP01002466.1_1 - 8.3e-45 153.9 0.2 1.1e-44 153.6 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01002466.1_1 - 3.1e-05 23.2 0.0 3.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Glucosaminidase PF01832.20 AAAP01002466.1_1 - 0.00098 19.6 0.0 0.0022 18.5 0.0 1.6 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase UreD PF01774.17 AAAP01002466.1_2 - 5e-33 114.8 0.0 6.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein PEP_mutase PF13714.6 AAAP01002466.1_2 - 0.012 15.0 0.4 0.13 11.7 0.1 2.0 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase cobW PF02492.19 AAAP01002466.1_3 - 3e-15 56.3 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AAAP01002466.1_3 - 0.0001 21.4 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DDE_3 PF13358.6 AAAP01002467.1_3 - 1.8e-12 47.2 0.1 3.1e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_tran PF00005.27 AAAP01002468.1_1 - 1.8e-28 99.8 0.0 2.1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002468.1_1 - 0.054 13.3 0.0 2 8.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01002468.1_1 - 0.057 13.8 0.3 0.13 12.7 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAAP01002468.1_1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01002468.1_1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAAP01002468.1_1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain MacB_PCD PF12704.7 AAAP01002468.1_2 - 2.7e-17 63.8 3.0 4.3e-17 63.1 3.0 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 AAAP01002468.1_2 - 1.2e-13 51.3 2.3 1.2e-13 51.3 2.3 3.1 3 1 0 3 3 3 1 FtsX-like permease family Clc-like PF07062.12 AAAP01002468.1_2 - 1.2 8.5 2.9 7.4 6.0 0.2 2.3 2 0 0 2 2 2 0 Clc-like FliMN_C PF01052.20 AAAP01002470.1_2 - 3.3e-20 71.9 1.1 4.4e-20 71.5 1.1 1.2 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term BPL_LplA_LipB PF03099.19 AAAP01002470.1_3 - 4.8e-05 23.3 0.0 7.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family OprB PF04966.12 AAAP01002471.1_2 - 3.5e-36 125.4 0.5 4.1e-36 125.2 0.5 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family ACP PF06857.11 AAAP01002472.1_2 - 7.5e-21 74.2 0.0 8.6e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) Mal_decarbox_Al PF16957.5 AAAP01002472.1_3 - 1.9e-178 594.2 0.0 2.2e-178 594.0 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 AAAP01002472.1_3 - 0.0052 16.7 0.2 0.61 10.0 0.0 2.3 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_108 PF05838.12 AAAP01002473.1_2 - 5.8e-29 100.4 0.0 8.4e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 108 PG_binding_3 PF09374.10 AAAP01002473.1_2 - 3.9e-10 39.8 0.1 6.2e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Predicted Peptidoglycan domain GTA_holin_3TM PF11351.8 AAAP01002473.1_3 - 4.4e-18 66.0 0.6 6e-18 65.6 0.6 1.1 1 0 0 1 1 1 1 Holin of 3TMs, for gene-transfer release DUF2389 PF09493.10 AAAP01002473.1_3 - 0.024 15.3 0.5 0.034 14.8 0.5 1.2 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) DUF4770 PF15994.5 AAAP01002473.1_3 - 0.13 12.5 0.0 0.15 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4112 PF13430.6 AAAP01002473.1_3 - 0.29 11.4 1.5 3.6 7.9 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4112) HWE_HK PF07536.14 AAAP01002474.1_1 - 5.4e-17 62.3 0.9 8.7e-17 61.6 0.9 1.3 1 0 0 1 1 1 1 HWE histidine kinase PAS_9 PF13426.7 AAAP01002474.1_1 - 1.9e-07 31.3 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 PAS domain HisKA_2 PF07568.12 AAAP01002474.1_1 - 6e-07 29.5 0.2 9.4e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase PAS_4 PF08448.10 AAAP01002474.1_1 - 1.9e-05 24.8 6.4 3e-05 24.2 0.2 2.4 2 1 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAAP01002474.1_1 - 0.0065 16.7 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01002474.1_1 - 0.038 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold PGM_PMM_I PF02878.16 AAAP01002475.1_1 - 9.8e-28 96.6 0.1 2.3e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AAAP01002475.1_1 - 3.4e-23 82.2 0.3 9.7e-23 80.8 0.3 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AAAP01002475.1_1 - 3.8e-15 56.1 0.0 7.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AAAP01002475.1_1 - 4.1e-12 46.1 0.0 1.5e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DeoC PF01791.9 AAAP01002475.1_2 - 5.4e-18 65.5 1.8 6.7e-18 65.2 1.8 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 AAAP01002475.1_2 - 0.004 16.4 1.0 0.007 15.6 0.6 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase 4HBT PF03061.22 AAAP01002476.1_2 - 1.6e-13 50.8 0.1 2.2e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MarR_2 PF12802.7 AAAP01002476.1_3 - 4.1e-10 39.4 0.0 8e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01002476.1_3 - 2.2e-09 37.1 0.0 4.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01002476.1_3 - 1.3e-06 28.8 0.0 2.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 AAAP01002476.1_3 - 1.8e-06 28.0 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain ACC_epsilon PF13822.6 AAAP01002476.1_3 - 0.015 15.9 0.1 0.015 15.9 0.1 1.9 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit PadR PF03551.14 AAAP01002476.1_3 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family B-block_TFIIIC PF04182.12 AAAP01002476.1_3 - 0.068 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Peripla_BP_6 PF13458.6 AAAP01002477.1_1 - 0.0024 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 AAAP01002477.1_2 - 1.3e-22 80.8 0.0 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002477.1_2 - 1.7e-12 47.8 0.0 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01002477.1_2 - 3.8e-05 24.0 0.0 0.00031 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01002477.1_2 - 4.6e-05 23.9 0.4 0.0001 22.8 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01002477.1_2 - 0.00014 21.5 1.2 0.0002 21.0 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01002477.1_2 - 0.00028 20.7 0.6 0.0028 17.4 0.2 2.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAAP01002477.1_2 - 0.00073 20.1 0.0 0.0011 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01002477.1_2 - 0.0009 19.5 0.4 0.0041 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AAAP01002477.1_2 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01002477.1_2 - 0.0044 16.6 0.1 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 AAAP01002477.1_2 - 0.0051 16.3 0.0 0.072 12.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain TsaE PF02367.17 AAAP01002477.1_2 - 0.0069 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 AAAP01002477.1_2 - 0.0071 16.9 0.2 0.021 15.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AAAP01002477.1_2 - 0.011 15.5 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AAAP01002477.1_2 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 AAAP01002477.1_2 - 0.012 15.0 0.1 0.027 13.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAAP01002477.1_2 - 0.013 15.7 0.4 0.025 14.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01002477.1_2 - 0.016 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF3584 PF12128.8 AAAP01002477.1_2 - 0.017 12.7 0.1 0.024 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 AAAP01002477.1_2 - 0.017 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 AAAP01002477.1_2 - 0.018 14.6 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 AAAP01002477.1_2 - 0.035 13.7 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 AAAP01002477.1_2 - 0.041 13.6 0.1 0.52 10.0 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 AAAP01002477.1_2 - 0.041 12.7 0.1 0.097 11.4 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MukB PF04310.12 AAAP01002477.1_2 - 0.051 13.4 0.5 0.11 12.3 0.5 1.5 1 1 0 1 1 1 0 MukB N-terminal MobB PF03205.14 AAAP01002477.1_2 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 AAAP01002477.1_2 - 0.098 12.7 0.0 0.35 10.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AAAP01002477.1_2 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01002477.1_2 - 0.12 11.7 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 AAAP01002477.1_2 - 0.13 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 AAAP01002477.1_2 - 0.17 12.3 0.1 0.31 11.5 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AAAP01002477.1_2 - 0.21 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FAD_binding_5 PF00941.21 AAAP01002478.1_1 - 3e-48 163.8 0.0 4.1e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAAP01002478.1_1 - 2.2e-14 53.5 1.9 2.2e-14 53.5 1.9 2.2 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain DUF4567 PF15131.6 AAAP01002478.1_1 - 0.23 11.5 2.7 0.18 11.9 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) Fer2_2 PF01799.20 AAAP01002478.1_2 - 4.3e-30 103.6 0.1 4.3e-30 103.6 0.1 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01002478.1_2 - 1.8e-08 34.2 0.3 1.8e-08 34.2 0.3 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01002478.1_2 - 8.2e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF5634_N PF18672.1 AAAP01002478.1_2 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5634) Amidohydro_1 PF01979.20 AAAP01002479.1_1 - 7.3e-13 48.5 0.0 8.6e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01002479.1_1 - 5e-11 42.7 0.2 6.1e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family LysR_substrate PF03466.20 AAAP01002479.1_2 - 2.9e-26 92.1 4.5 3.9e-26 91.7 4.5 1.0 1 0 0 1 1 1 1 LysR substrate binding domain HTH_23 PF13384.6 AAAP01002480.1_1 - 9.1e-10 38.1 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01002480.1_1 - 2e-08 34.2 0.1 2.7e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01002480.1_1 - 4.9e-06 26.5 0.1 5.9e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_4 PF13613.6 AAAP01002480.1_1 - 0.0012 18.5 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease LZ_Tnp_IS481 PF13011.6 AAAP01002480.1_1 - 0.0013 19.2 0.2 0.0015 19.0 0.2 1.2 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 DUF746 PF05344.11 AAAP01002480.1_1 - 0.0031 17.3 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) HTH_psq PF05225.16 AAAP01002480.1_1 - 0.0064 16.2 0.1 0.0095 15.7 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_IS630 PF01710.16 AAAP01002480.1_1 - 0.051 13.6 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_Tnp_1 PF01527.20 AAAP01002480.1_1 - 0.091 13.1 0.3 0.1 12.9 0.3 1.1 1 0 0 1 1 1 0 Transposase CedA PF10729.9 AAAP01002480.1_1 - 0.1 12.4 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Cell division activator CedA HTH_32 PF13565.6 AAAP01002480.1_1 - 0.1 13.2 0.7 0.63 10.7 0.2 2.0 1 1 1 2 2 2 0 Homeodomain-like domain DUF1804 PF08822.11 AAAP01002480.1_1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Arm-DNA-bind_3 PF13356.6 AAAP01002480.1_2 - 1.4e-14 54.2 0.1 3.4e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 AAAP01002480.1_2 - 5.2e-05 23.4 0.0 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 AAAP01002480.1_2 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family RNA_pol_Rpb2_6 PF00562.28 AAAP01002481.1_1 - 5.4e-87 292.4 0.3 7e-87 292.0 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 AAAP01002481.1_1 - 1.2e-27 96.2 0.0 1.8e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 TerB PF05099.13 AAAP01002482.1_1 - 5.7e-09 36.1 0.1 6.6e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TerB LrgB PF04172.16 AAAP01002482.1_2 - 7.4e-72 241.3 21.0 7.4e-72 241.3 21.0 2.0 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 AAAP01002482.1_2 - 1.1e-22 79.8 6.0 1.1e-22 79.8 6.0 3.3 3 0 0 3 3 3 1 LrgA family CPP1-like PF11833.8 AAAP01002482.1_2 - 0.25 11.0 5.5 0.069 12.8 1.1 2.2 1 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TssN PF17555.2 AAAP01002482.1_2 - 1.1 8.6 4.2 0.19 11.1 0.4 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF1180 PF06679.12 AAAP01002482.1_2 - 1.7 9.0 5.1 0.33 11.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) adh_short_C2 PF13561.6 AAAP01002483.1_1 - 2e-57 194.4 2.3 2.3e-57 194.3 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002483.1_1 - 1.7e-47 161.4 0.3 2e-47 161.2 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01002483.1_1 - 1.7e-10 41.1 1.0 2.6e-10 40.5 1.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01002483.1_1 - 0.013 15.0 0.7 0.087 12.3 0.7 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MR_MLE_C PF13378.6 AAAP01002483.1_2 - 6.5e-61 205.7 0.1 7.6e-61 205.5 0.1 1.0 1 0 0 1 1 1 1 Enolase C-terminal domain-like SRAP PF02586.14 AAAP01002484.1_1 - 8.8e-59 198.7 0.0 1e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) FemAB_like PF04339.12 AAAP01002484.1_2 - 3.2e-157 523.4 0.0 3.6e-157 523.3 0.0 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 AAAP01002484.1_2 - 7.9e-13 48.8 3.1 7.9e-13 48.8 3.1 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Synapsin_N PF10581.9 AAAP01002485.1_1 - 0.028 14.4 1.1 0.067 13.1 0.1 2.1 2 0 0 2 2 2 0 Synapsin N-terminal Pept_tRNA_hydro PF01195.19 AAAP01002486.1_1 - 9.5e-12 45.2 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase MMR_HSR1 PF01926.23 AAAP01002486.1_2 - 7.1e-25 87.3 0.0 9e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01002486.1_2 - 2.2e-08 33.8 0.1 3.8e-08 33.0 0.0 1.7 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 AAAP01002486.1_2 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2635 PF10948.8 AAAP01002486.1_2 - 0.069 12.9 0.2 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Arf PF00025.21 AAAP01002486.1_2 - 0.089 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.23 AAAP01002486.1_2 - 0.12 12.4 0.0 6.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Pox_A51 PF04948.13 AAAP01002486.1_2 - 0.22 10.4 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein ABC2_membrane PF01061.24 AAAP01002487.1_1 - 3.6e-38 131.1 21.4 5.1e-38 130.6 21.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01002487.1_1 - 3.7e-18 65.7 23.2 4.6e-18 65.4 23.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAAP01002487.1_1 - 1.5e-12 47.4 10.1 1.8e-12 47.1 10.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAAP01002487.1_1 - 0.0015 18.5 7.9 0.0032 17.5 7.9 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAAP01002487.1_1 - 0.09 12.3 11.8 0.035 13.7 7.7 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAAP01002487.1_2 - 1.6e-10 41.7 0.1 3.2e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAAP01002487.1_2 - 0.027 14.3 0.2 0.035 13.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 AAAP01002487.1_2 - 0.031 14.5 0.1 0.54 10.5 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit VHL_C PF17211.3 AAAP01002487.1_2 - 0.13 12.3 1.8 6.2 6.9 0.2 2.4 1 1 1 2 2 2 0 VHL box domain CCG PF02754.16 AAAP01002488.1_1 - 2.6e-13 50.0 0.2 2.8e-12 46.7 0.1 2.1 2 0 0 2 2 2 1 Cysteine-rich domain AhpC-TSA PF00578.21 AAAP01002488.1_2 - 6.7e-12 45.4 0.0 8.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01002488.1_2 - 1.9e-08 34.2 0.0 2.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AAAP01002488.1_2 - 0.00015 21.7 0.0 0.003 17.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AAAP01002488.1_2 - 0.0052 17.1 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Pro_isomerase PF00160.21 AAAP01002489.1_1 - 4e-07 30.4 0.0 4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 AAAP01002489.1_4 - 2.4e-26 92.9 0.1 2.9e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Hepcidin PF06446.12 AAAP01002490.1_1 - 0.086 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Hepcidin GCV_T PF01571.21 AAAP01002491.1_1 - 1.8e-08 34.1 0.0 2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain TrmE_N PF10396.9 AAAP01002492.1_1 - 2.1e-36 124.7 0.0 2.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 AAAP01002492.1_1 - 0.0031 17.7 0.4 0.0053 16.9 0.4 1.4 1 0 0 1 1 1 1 MnmE helical domain DUF4148 PF13663.6 AAAP01002492.1_1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) 2Fe-2S_thioredx PF01257.19 AAAP01002492.1_2 - 0.0022 17.9 0.0 0.0032 17.3 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 AAAP01002492.1_2 - 0.0029 18.0 0.0 0.0034 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1636) Methyltransf_31 PF13847.6 AAAP01002493.1_1 - 0.032 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SseC PF04888.12 AAAP01002493.1_1 - 0.13 11.8 1.0 0.18 11.4 1.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4159 PF13709.6 AAAP01002493.1_2 - 1.6e-22 80.0 0.0 1.8e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) MFS_1 PF07690.16 AAAP01002494.1_2 - 0.0051 15.8 1.6 0.0051 15.8 1.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3775 PF12616.8 AAAP01002494.1_2 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) SLATT_1 PF18181.1 AAAP01002494.1_2 - 0.54 10.2 3.9 1.3 9.0 3.9 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Phage_holin_3_6 PF07332.11 AAAP01002494.1_2 - 3.2 7.8 21.8 0.75 9.9 8.0 2.8 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Colicin_V PF02674.16 AAAP01002494.1_2 - 8.4 6.4 11.7 0.41 10.6 0.4 2.6 2 1 1 3 3 3 0 Colicin V production protein DUF3072 PF11272.8 AAAP01002495.1_1 - 1.4e-30 105.0 2.5 2.4e-30 104.2 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3072) IATP PF04568.12 AAAP01002495.1_1 - 0.072 13.5 0.5 0.082 13.3 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PBP_N PF17093.5 AAAP01002495.1_1 - 0.19 11.9 2.2 0.23 11.7 2.2 1.0 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Aminotran_4 PF01063.19 AAAP01002495.1_2 - 2.2e-47 161.8 0.0 2.6e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_trans_1_4 PF13692.6 AAAP01002496.1_1 - 4.4e-14 53.1 0.0 8.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01002496.1_1 - 2.7e-13 49.8 0.0 3.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01002496.1_1 - 3.2e-05 24.0 2.4 4.4e-05 23.5 1.3 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01002496.1_1 - 0.0054 17.2 2.2 0.0054 17.2 2.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain DUF308 PF03729.13 AAAP01002497.1_2 - 1.2e-18 67.1 33.3 5.9e-14 52.1 14.3 2.2 1 1 1 2 2 2 2 Short repeat of unknown function (DUF308) DUF4203 PF13886.6 AAAP01002497.1_2 - 0.37 10.4 20.5 0.21 11.2 4.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) EMP70 PF02990.16 AAAP01002497.1_2 - 0.6 8.7 6.5 0.69 8.5 6.5 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4064 PF13273.6 AAAP01002497.1_2 - 1.9 8.8 19.8 17 5.7 11.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF308 PF03729.13 AAAP01002497.1_3 - 8.5e-06 26.0 0.8 9.8e-06 25.8 0.8 1.0 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) DUF3180 PF11377.8 AAAP01002497.1_3 - 0.0062 16.7 0.1 0.0064 16.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) Ycf4 PF02392.16 AAAP01002497.1_5 - 0.01 15.4 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Ycf4 DUF2157 PF09925.9 AAAP01002497.1_5 - 0.013 15.3 0.2 0.014 15.2 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4029 PF13221.6 AAAP01002497.1_5 - 0.042 14.5 0.2 0.055 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) Proton_antipo_M PF00361.20 AAAP01002497.1_5 - 0.062 12.5 1.1 0.081 12.1 1.1 1.0 1 0 0 1 1 1 0 Proton-conducting membrane transporter FeoB_C PF07664.12 AAAP01002497.1_5 - 1.3 8.7 3.9 1.4 8.7 0.3 2.1 1 1 1 2 2 2 0 Ferrous iron transport protein B C terminus Ald_Xan_dh_C2 PF02738.18 AAAP01002498.1_1 - 9.4e-91 304.9 0.4 1.2e-90 304.6 0.4 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase SUKH-4 PF14435.6 AAAP01002498.1_1 - 0.054 13.5 0.1 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 SUKH-4 immunity protein CinA PF02464.17 AAAP01002498.1_2 - 4.3e-27 94.6 0.3 5e-27 94.4 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein Oxidored_FMN PF00724.20 AAAP01002500.1_1 - 4.9e-09 35.9 0.0 5.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HTH_20 PF12840.7 AAAP01002500.1_2 - 2.2e-12 46.8 0.0 2.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAAP01002500.1_2 - 3.8e-07 29.9 0.1 1.6e-05 24.6 0.2 2.6 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AAAP01002500.1_2 - 0.00021 21.0 0.4 0.00028 20.6 0.4 1.4 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_36 PF13730.6 AAAP01002500.1_2 - 0.00076 19.4 0.2 0.027 14.4 0.1 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01002500.1_2 - 0.0011 18.5 0.2 0.0033 17.0 0.1 1.9 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AAAP01002500.1_2 - 0.0015 18.3 0.4 0.0024 17.7 0.4 1.4 1 1 0 1 1 1 1 MarR family TrmB PF01978.19 AAAP01002500.1_2 - 0.0052 16.6 0.1 0.008 16.0 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAAP01002500.1_2 - 0.0085 16.4 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_40 PF14493.6 AAAP01002500.1_2 - 0.032 14.7 0.0 0.045 14.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01002500.1_2 - 0.044 13.6 0.1 0.072 12.9 0.1 1.6 1 1 0 1 1 1 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 AAAP01002500.1_2 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAAP01002500.1_2 - 0.12 12.3 0.0 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 HTH domain Bac_luciferase PF00296.20 AAAP01002500.1_3 - 1.6e-28 100.1 0.3 1.9e-28 99.8 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase PBP_like_2 PF12849.7 AAAP01002501.1_1 - 4.4e-22 79.1 0.2 5.5e-22 78.7 0.2 1.0 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAAP01002501.1_1 - 1.6e-09 37.9 0.1 1.9e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AAAP01002501.1_1 - 0.00019 20.9 0.0 0.00036 20.0 0.0 1.5 1 1 0 1 1 1 1 LysR substrate binding domain SBP_bac_1 PF01547.25 AAAP01002501.1_1 - 0.00068 19.7 0.0 0.00075 19.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein OpuAC PF04069.12 AAAP01002501.1_1 - 0.00079 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system PBP_like PF12727.7 AAAP01002501.1_1 - 0.0071 15.5 0.1 0.016 14.3 0.1 1.7 1 1 0 1 1 1 1 PBP superfamily domain ABC_tran PF00005.27 AAAP01002501.1_2 - 3.5e-25 89.1 0.0 6.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002501.1_2 - 5e-14 52.8 0.4 4.5e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01002501.1_2 - 4e-06 26.4 0.0 0.07 12.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAAP01002501.1_2 - 7.7e-05 22.5 0.9 0.00017 21.4 0.9 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01002501.1_2 - 0.00054 19.8 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01002501.1_2 - 0.0032 17.2 0.1 0.007 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01002501.1_2 - 0.019 15.2 0.1 0.057 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01002501.1_2 - 0.019 14.5 1.4 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAAP01002501.1_2 - 0.035 14.3 0.8 1 9.6 0.3 2.6 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 AAAP01002501.1_2 - 0.036 14.6 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01002501.1_2 - 0.052 13.1 0.0 0.089 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01002501.1_2 - 0.069 13.5 2.4 0.11 12.9 2.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain MukB PF04310.12 AAAP01002501.1_2 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal BPD_transp_1 PF00528.22 AAAP01002501.1_3 - 0.0085 15.8 0.7 0.0098 15.6 0.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component HlyD_D23 PF16576.5 AAAP01002502.1_1 - 5.4e-11 42.1 0.0 1.3e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01002502.1_1 - 2.5e-05 24.0 0.2 9.8e-05 22.1 0.0 2.1 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01002502.1_1 - 0.018 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme HlyD_3 PF13437.6 AAAP01002502.1_1 - 0.052 14.3 0.1 0.19 12.5 0.0 1.8 2 0 0 2 2 2 0 HlyD family secretion protein PTS_EIIA_1 PF00358.20 AAAP01002502.1_1 - 0.091 12.5 0.1 0.27 11.0 0.1 1.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 AAAP01002502.1_1 - 0.11 12.2 0.1 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain LepA_C PF06421.12 AAAP01002502.1_2 - 1.3e-50 170.1 0.3 1.7e-50 169.7 0.3 1.2 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AAAP01002502.1_2 - 7.9e-21 73.9 0.0 3.2e-20 71.9 0.0 2.1 3 0 0 3 3 3 1 Elongation factor G C-terminus EFG_II PF14492.6 AAAP01002502.1_2 - 0.021 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II RF3_C PF16658.5 AAAP01002502.1_2 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain PTA_PTB PF01515.19 AAAP01002503.1_1 - 2.9e-63 214.1 0.1 3.3e-63 213.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase MdoG PF04349.12 AAAP01002504.1_1 - 7.3e-64 216.4 0.0 8.9e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG DUF188 PF02639.14 AAAP01002505.1_1 - 3.5e-16 59.1 0.0 3.9e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 SNN_cytoplasm PF09051.10 AAAP01002505.1_1 - 0.0055 16.5 0.2 0.0089 15.9 0.2 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic Citrate_synt PF00285.21 AAAP01002505.1_2 - 5.5e-50 170.5 0.0 6.1e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FAD_binding_3 PF01494.19 AAAP01002505.1_2 - 0.013 14.8 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain NUDIX PF00293.28 AAAP01002506.1_1 - 4.8e-13 49.3 0.0 5.3e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAAP01002506.1_1 - 3.4e-09 36.7 0.0 3.8e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Dus PF01207.17 AAAP01002507.1_2 - 1.2e-92 310.3 0.0 1.4e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AAAP01002507.1_2 - 2.2e-06 27.3 0.9 0.003 17.1 0.1 1.7 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 AAAP01002507.1_2 - 1.3e-05 24.8 10.5 0.00024 20.6 0.8 2.9 3 0 0 3 3 3 2 Nitronate monooxygenase DHO_dh PF01180.21 AAAP01002507.1_2 - 5.4e-05 22.5 0.0 0.014 14.6 0.0 2.1 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase SOR_SNZ PF01680.17 AAAP01002507.1_2 - 0.00092 19.0 1.9 0.67 9.7 0.0 2.5 1 1 1 2 2 2 2 SOR/SNZ family NanE PF04131.14 AAAP01002507.1_2 - 0.00098 18.4 1.5 0.001 18.3 0.0 1.7 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.6 AAAP01002507.1_2 - 0.0021 17.5 3.6 0.033 13.6 3.6 2.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pterin_bind PF00809.22 AAAP01002507.1_2 - 0.051 13.3 0.7 0.13 11.9 0.2 1.9 2 0 0 2 2 2 0 Pterin binding enzyme Oxidored_FMN PF00724.20 AAAP01002507.1_2 - 0.24 10.6 0.2 3.5 6.8 0.0 2.4 2 1 1 3 3 3 0 NADH:flavin oxidoreductase / NADH oxidase family MCPsignal PF00015.21 AAAP01002508.1_1 - 5.1e-28 98.0 29.1 5.1e-28 98.0 29.1 5.4 3 1 1 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01002508.1_1 - 4.2e-11 43.0 0.5 4.2e-11 43.0 0.5 5.5 5 1 1 6 6 6 1 HAMP domain T7SS_ESX_EspC PF10824.8 AAAP01002508.1_1 - 0.01 16.3 1.9 0.01 16.3 1.9 6.2 3 3 5 8 8 8 0 Excreted virulence factor EspC, type VII ESX diderm DUF948 PF06103.11 AAAP01002508.1_1 - 0.55 10.5 24.3 1.9 8.8 1.6 5.3 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AAAP01002508.1_1 - 0.83 9.8 5.5 18 5.5 0.2 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family GDWWSH PF15667.5 AAAP01002508.1_1 - 0.99 8.8 4.0 2.3 7.6 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH UPF0242 PF06785.11 AAAP01002508.1_1 - 1.1 9.4 5.5 6.6 6.8 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FH2 PF02181.23 AAAP01002508.1_1 - 1.4 7.9 6.0 0.82 8.7 0.3 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain COG2 PF06148.11 AAAP01002508.1_1 - 6.6 6.8 10.6 12 6.0 1.0 3.5 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Med22 PF06179.12 AAAP01002508.1_1 - 9.9 6.4 9.2 1.2 9.4 0.6 3.3 3 1 0 3 3 3 0 Surfeit locus protein 5 subunit 22 of Mediator complex FmdA_AmdA PF03069.15 AAAP01002509.1_1 - 6.9e-174 578.0 0.0 7.9e-174 577.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Zn-ribbon_8 PF09723.10 AAAP01002509.1_2 - 1.5e-11 44.2 6.4 2.5e-11 43.5 6.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 AAAP01002509.1_2 - 0.026 14.6 1.7 0.04 14.0 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF305 PF03713.13 AAAP01002510.1_1 - 4.6e-09 36.6 10.8 5.1e-09 36.4 10.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 AAAP01002510.1_1 - 0.00012 22.3 1.7 0.00015 22.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) Amidohydro_3 PF07969.11 AAAP01002511.1_1 - 0.002 17.7 0.0 0.002 17.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AAAP01002511.1_1 - 0.036 13.4 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase family G3P_acyltransf PF02660.15 AAAP01002511.1_2 - 4e-48 163.6 15.3 4.7e-48 163.3 15.3 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase DUF3817 PF12823.7 AAAP01002511.1_2 - 0.44 11.4 6.7 0.36 11.7 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) DNA_processg_A PF02481.15 AAAP01002511.1_3 - 1.2e-32 112.8 0.5 1.5e-32 112.5 0.5 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A SGL PF08450.12 AAAP01002512.1_1 - 4.6e-53 180.3 0.0 5.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AAAP01002512.1_1 - 0.00067 19.6 0.3 0.33 11.1 0.0 3.4 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.20 AAAP01002512.1_1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.7 2 0 0 2 2 2 0 Arylesterase Str_synth PF03088.16 AAAP01002512.1_1 - 0.027 14.6 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 Strictosidine synthase Reg_prop PF07494.11 AAAP01002512.1_1 - 0.038 14.2 2.5 57 4.4 0.2 5.0 4 2 2 6 6 6 0 Two component regulator propeller DUF3659 PF12396.8 AAAP01002512.1_1 - 0.073 13.0 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Cupin_2 PF07883.11 AAAP01002512.1_2 - 3.6e-05 23.4 0.3 0.00017 21.3 0.1 2.1 1 1 1 2 2 2 1 Cupin domain PBP_like_2 PF12849.7 AAAP01002513.1_1 - 9e-50 169.9 2.6 1.1e-49 169.6 2.6 1.0 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 AAAP01002513.1_1 - 9.6e-11 42.2 5.1 1.3e-10 41.7 5.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAAP01002513.1_1 - 2.2e-07 30.2 0.1 5e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAAP01002513.1_1 - 0.00052 19.8 0.1 0.0029 17.4 0.0 1.9 1 1 0 2 2 2 1 Bacterial extracellular solute-binding protein Iso_dh PF00180.20 AAAP01002514.1_2 - 1.2e-76 258.2 0.0 1.5e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 AAAP01002514.1_2 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4875) DUF1345 PF07077.11 AAAP01002515.1_2 - 2.6e-32 111.9 5.5 4.1e-32 111.3 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) Enolase_like_N PF18374.1 AAAP01002515.1_3 - 2.5e-25 87.6 0.8 3.5e-25 87.1 0.8 1.2 1 0 0 1 1 1 1 Enolase N-terminal domain-like PAS_5 PF07310.13 AAAP01002516.1_1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 PAS domain PilZ PF07238.14 AAAP01002516.1_2 - 1.1e-18 67.4 0.4 3.4e-10 40.2 0.2 2.3 2 1 0 2 2 2 2 PilZ domain STAT1_TAZ2bind PF12162.8 AAAP01002516.1_2 - 0.11 12.0 0.0 0.35 10.5 0.0 1.9 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain ABC2_membrane PF01061.24 AAAP01002517.1_1 - 7.4e-36 123.5 27.8 7.4e-36 123.5 27.8 1.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01002517.1_1 - 1.1e-06 28.0 29.2 1.1e-06 28.0 29.2 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 AAAP01002517.1_2 - 3.8e-06 26.9 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAAP01002517.1_2 - 0.00015 22.3 0.2 0.0004 20.9 0.0 1.8 2 1 0 2 2 2 1 ABC transporter DUF4162 PF13732.6 AAAP01002517.1_2 - 0.0016 19.1 0.0 0.017 15.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) Hydrolase PF00702.26 AAAP01002517.1_2 - 0.0031 17.8 0.1 0.0047 17.2 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATPase PF06745.13 AAAP01002517.1_2 - 0.011 15.2 0.2 0.015 14.7 0.2 1.2 1 0 0 1 1 1 0 KaiC OSK PF17182.4 AAAP01002517.1_2 - 0.067 12.4 0.1 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 OSK domain AAA_24 PF13479.6 AAAP01002517.1_2 - 0.091 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Flg_hook PF02120.16 AAAP01002517.1_2 - 0.12 12.3 0.3 9.5 6.2 0.0 2.9 3 1 1 4 4 4 0 Flagellar hook-length control protein FliK Cellulase-like PF12876.7 AAAP01002517.1_2 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like Methyltransf_12 PF08242.12 AAAP01002518.1_1 - 1.3e-15 58.0 0.0 2.1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002518.1_1 - 9.2e-15 55.1 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002518.1_1 - 7.5e-13 48.9 0.0 5.6e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002518.1_1 - 3.3e-12 46.4 0.0 4.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002518.1_1 - 5.1e-11 42.7 0.0 3.7e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01002518.1_1 - 1e-06 28.2 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 AAAP01002518.1_1 - 4.2e-06 25.9 0.0 6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 AAAP01002518.1_1 - 5.9e-05 22.5 0.0 7.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 AAAP01002518.1_1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 AAAP01002518.1_1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 AAAP01002518.1_1 - 0.026 14.0 0.0 4.2 6.8 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain TPMT PF05724.11 AAAP01002518.1_1 - 0.042 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CSD PF00313.22 AAAP01002519.1_1 - 3e-26 91.1 0.1 3.2e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01002519.1_1 - 4e-05 23.2 0.3 7.2e-05 22.4 0.3 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 AAAP01002519.1_1 - 0.0015 18.3 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain CusF_Ec PF11604.8 AAAP01002519.1_1 - 0.044 13.7 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Borrelia_P83 PF05262.11 AAAP01002519.1_2 - 1 7.8 13.7 1.2 7.6 13.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein SIS PF01380.22 AAAP01002520.1_1 - 3.3e-25 88.4 0.0 4.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AAAP01002520.1_1 - 0.0025 17.8 0.5 0.29 11.2 0.0 2.3 1 1 1 2 2 2 2 SIS domain PAP2 PF01569.21 AAAP01002521.1_2 - 0.0037 17.0 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily RNase_T PF00929.24 AAAP01002522.1_1 - 5.5e-07 30.3 0.0 8.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Phage_H_T_join PF05521.11 AAAP01002523.1_1 - 1.4e-08 35.1 0.0 1.6e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 Phage head-tail joining protein Phage_connect_1 PF05135.13 AAAP01002523.1_2 - 0.0011 19.5 0.0 0.0099 16.4 0.0 2.0 2 0 0 2 2 2 1 Phage gp6-like head-tail connector protein Trypsin PF00089.26 AAAP01002523.1_3 - 6.4e-19 68.6 0.0 8.4e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 AAAP01002523.1_3 - 1.2e-11 45.7 1.0 1.9e-11 45.1 1.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Formyl_trans_N PF00551.19 AAAP01002524.1_1 - 9.5e-09 35.2 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AAAP01002524.1_1 - 2.8e-05 24.3 0.0 4.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain adh_short PF00106.25 AAAP01002524.1_2 - 7e-09 35.4 0.0 7.8e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002524.1_2 - 5.1e-05 22.9 0.0 6.4e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 AAAP01002524.1_2 - 0.00046 19.7 0.0 0.00051 19.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAAP01002524.1_2 - 0.00069 19.6 0.4 0.00076 19.4 0.4 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01002524.1_2 - 0.0025 17.7 0.8 0.0028 17.6 0.8 1.1 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 AAAP01002524.1_2 - 0.048 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 TrkA-N domain LytR_C PF13399.6 AAAP01002524.1_2 - 0.051 14.6 0.6 1.6 9.8 0.1 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator ApbA PF02558.16 AAAP01002524.1_2 - 0.12 12.0 0.3 0.14 11.8 0.3 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 AAAP01002524.1_2 - 0.17 12.1 0.1 0.19 12.0 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1501 PF07394.12 AAAP01002525.1_1 - 1.8e-05 24.0 0.0 3.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) DUF1800 PF08811.11 AAAP01002525.1_2 - 2.8e-120 402.3 0.0 3.1e-120 402.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) PSD2 PF07624.11 AAAP01002525.1_2 - 0.021 14.6 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) E1-E2_ATPase PF00122.20 AAAP01002526.1_1 - 8.2e-21 74.3 5.4 1e-20 74.0 5.4 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01002526.1_1 - 0.00029 21.2 0.1 0.00045 20.6 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SpoIIIAC PF06686.11 AAAP01002526.1_1 - 0.047 13.9 0.3 0.047 13.9 0.3 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Hydrolase PF00702.26 AAAP01002526.1_2 - 6.6e-25 88.6 2.3 9.5e-25 88.1 2.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01002526.1_2 - 0.00025 21.5 0.1 0.0016 18.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01002526.1_2 - 0.00064 19.5 0.6 0.002 17.9 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cadherin_4 PF17803.1 AAAP01002526.1_2 - 0.093 13.4 0.8 0.3 11.8 0.8 1.8 1 0 0 1 1 1 0 Bacterial cadherin-like domain KdpC PF02669.15 AAAP01002526.1_3 - 2.7e-28 99.0 0.1 3.4e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 K+-transporting ATPase, c chain Epimerase PF01370.21 AAAP01002527.1_1 - 1.3e-53 182.0 0.0 1.6e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01002527.1_1 - 6.4e-45 154.0 0.0 8e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01002527.1_1 - 1.1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01002527.1_1 - 2.2e-11 43.3 0.0 3.5e-11 42.6 0.0 1.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01002527.1_1 - 1.2e-10 41.0 0.0 5.5e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AAAP01002527.1_1 - 1.4e-05 25.1 0.1 4.8e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAAP01002527.1_1 - 9.5e-05 21.7 0.1 0.023 13.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AAAP01002527.1_1 - 0.0068 15.9 1.8 0.16 11.4 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase ssDBP_DBD PF18361.1 AAAP01002527.1_1 - 0.057 13.5 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Rossmann-like PF10727.9 AAAP01002527.1_1 - 0.057 13.3 0.1 0.67 9.8 0.0 2.2 1 1 1 2 2 2 0 Rossmann-like domain PRP4 PF08799.11 AAAP01002527.1_1 - 0.13 11.8 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like ECH_1 PF00378.20 AAAP01002528.1_1 - 2e-20 73.2 0.1 3.3e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01002528.1_1 - 6.3e-11 42.3 0.1 1.4e-10 41.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH_N PF02737.18 AAAP01002528.1_1 - 5.5e-06 26.4 0.0 3.3e-05 23.8 0.0 2.2 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAAP01002528.1_1 - 0.079 13.8 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Cys_Met_Meta_PP PF01053.20 AAAP01002529.1_1 - 5.7e-60 202.9 0.0 6.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAAP01002529.1_1 - 0.088 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V GDC-P PF02347.16 AAAP01002529.1_1 - 0.24 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 AAAP01002529.1_2 - 5.6e-10 38.3 0.0 6.1e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RMF PF04957.12 AAAP01002529.1_3 - 6.8e-05 23.0 0.0 7.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome modulation factor MCPsignal PF00015.21 AAAP01002530.1_1 - 3.6e-27 95.2 16.1 3.6e-27 95.2 16.1 2.9 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01002530.1_1 - 2.5e-10 40.6 0.9 2.5e-10 40.6 0.9 3.9 4 1 0 4 4 4 1 HAMP domain Fibin PF15819.5 AAAP01002530.1_1 - 0.063 13.0 0.3 0.063 13.0 0.3 2.2 2 1 1 3 3 3 0 Fin bud initiation factor homologue SEO_N PF14576.6 AAAP01002530.1_1 - 0.12 11.5 0.0 0.12 11.5 0.0 2.5 3 0 0 3 3 3 0 Sieve element occlusion N-terminus DUF4736 PF15883.5 AAAP01002530.1_1 - 0.26 11.0 3.2 1.7 8.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4736) DUF948 PF06103.11 AAAP01002530.1_1 - 7.7 6.9 25.2 2.8 8.2 0.5 5.2 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) GETHR PF05671.11 AAAP01002531.1_1 - 1.2e-07 30.9 1.7 1.2e-07 30.9 1.7 3.5 5 0 0 5 5 5 1 GETHR pentapeptide repeat (5 copies) DUF3750 PF12570.8 AAAP01002532.1_1 - 9.3e-44 149.2 0.6 9.3e-44 149.2 0.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3750) Plug PF07715.15 AAAP01002532.1_2 - 2.7e-19 69.7 1.2 2.7e-19 69.7 1.2 2.3 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain DNA_pol_A_exo1 PF01612.20 AAAP01002533.1_2 - 4.4e-31 107.9 0.0 5.4e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease RNase_H_2 PF13482.6 AAAP01002533.1_2 - 0.0095 15.9 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 RNase_H superfamily HHH_3 PF12836.7 AAAP01002533.1_3 - 4.9e-12 45.9 0.0 5.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AAAP01002533.1_3 - 0.0013 18.5 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.11 AAAP01002533.1_3 - 0.0046 16.9 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_2 PF12826.7 AAAP01002533.1_3 - 0.084 13.0 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif Mur_ligase PF01225.25 AAAP01002535.1_1 - 2.6e-08 34.1 0.1 3.1e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Transpeptidase PF00905.22 AAAP01002535.1_2 - 5.6e-30 104.6 0.1 7.2e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain MutS_III PF05192.18 AAAP01002536.1_1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 MutS domain III T2SSF PF00482.23 AAAP01002536.1_2 - 2.3e-19 69.6 1.7 3.6e-19 68.9 1.7 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Gram_pos_anchor PF00746.21 AAAP01002536.1_2 - 5.5 7.0 5.9 3.5 7.7 0.3 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Man-6-P_recep PF02157.15 AAAP01002537.1_1 - 0.092 11.8 1.5 0.1 11.7 1.5 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor SBP_bac_3 PF00497.20 AAAP01002537.1_2 - 5.6e-24 84.8 0.0 7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAAP01002537.1_2 - 0.0038 17.2 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like MFS_1 PF07690.16 AAAP01002538.1_1 - 8.1e-35 120.4 49.9 8.1e-35 120.4 49.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 AAAP01002538.1_1 - 0.00086 18.3 0.2 0.00086 18.3 0.2 2.2 2 0 0 2 2 2 1 POT family OATP PF03137.20 AAAP01002538.1_1 - 2 6.6 13.2 0.041 12.2 5.9 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pribosyltran PF00156.27 AAAP01002538.1_2 - 4.2e-05 23.1 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Amidohydro_1 PF01979.20 AAAP01002539.1_1 - 6e-41 140.9 0.0 6.9e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01002539.1_1 - 4.2e-10 39.7 3.6 5.6e-10 39.3 3.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.22 AAAP01002539.1_1 - 0.025 13.9 0.0 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Adenosine/AMP deaminase T7SS_ESX_EspC PF10824.8 AAAP01002539.1_1 - 0.18 12.3 2.2 2.1 8.8 0.0 3.0 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Acetyltransf_1 PF00583.25 AAAP01002539.1_2 - 2.2e-15 56.9 0.0 2.7e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01002539.1_2 - 1.8e-12 47.5 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01002539.1_2 - 9.9e-09 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01002539.1_2 - 2.7e-06 28.1 0.0 3.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01002539.1_2 - 0.00041 20.4 0.0 0.00089 19.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAAP01002539.1_2 - 0.00052 20.1 0.0 0.0021 18.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01002539.1_2 - 0.00099 19.0 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AAAP01002539.1_2 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAAP01002539.1_2 - 0.04 14.1 2.7 0.081 13.1 2.7 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Toprim PF01751.22 AAAP01002539.1_2 - 0.042 14.1 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 Toprim domain HATPase_c PF02518.26 AAAP01002540.1_1 - 0.00014 22.3 0.1 0.00064 20.2 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01002540.1_1 - 0.12 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 GHKL domain Heme_oxygenase PF01126.20 AAAP01002540.1_2 - 0.0027 17.5 0.1 0.022 14.5 0.1 2.0 1 1 0 1 1 1 1 Heme oxygenase Holin_9 PF16936.5 AAAP01002540.1_3 - 0.042 14.0 0.2 0.044 14.0 0.2 1.1 1 0 0 1 1 1 0 Putative holin FlgN PF05130.12 AAAP01002541.1_3 - 6.2e-05 23.5 4.0 0.015 15.8 2.4 2.0 1 1 0 2 2 2 2 FlgN protein Rod-binding PF10135.9 AAAP01002541.1_4 - 2.2e-11 44.2 1.3 3.8e-11 43.4 0.1 2.0 2 1 1 3 3 3 1 Rod binding protein FTR1 PF03239.14 AAAP01002542.1_1 - 3.8e-24 85.4 17.0 5e-24 85.0 17.0 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family OFeT_1 PF16955.5 AAAP01002542.1_1 - 0.0027 17.4 5.8 0.018 14.8 5.5 2.2 1 1 1 2 2 2 1 Ferrous iron uptake permease, iron-lead transporter DUF2339 PF10101.9 AAAP01002542.1_1 - 0.066 11.8 29.0 0.05 12.2 25.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2339) MnhB PF04039.13 AAAP01002542.1_1 - 0.1 12.9 22.4 0.11 12.8 8.7 3.1 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF4131 PF13567.6 AAAP01002543.1_2 - 0.0031 17.2 0.2 0.0046 16.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF917 PF06032.12 AAAP01002543.1_3 - 0.0023 16.8 0.1 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF917) YjbE PF11106.8 AAAP01002543.1_3 - 0.74 10.1 3.5 1.1 9.5 3.5 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Ost5 PF05251.12 AAAP01002543.1_4 - 1.6 9.0 8.3 1.1 9.5 2.7 2.6 1 1 1 2 2 2 0 Oligosaccharyltransferase subunit 5 RelE PF06296.12 AAAP01002546.1_1 - 5e-09 36.3 0.2 5.5e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 RelE toxin of RelE / RelB toxin-antitoxin system SEF14_adhesin PF06443.11 AAAP01002546.1_1 - 0.039 13.8 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 SEF14-like adhesin TRM13 PF05206.14 AAAP01002546.1_1 - 0.14 11.7 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 HTH_3 PF01381.22 AAAP01002546.1_2 - 2.6e-06 27.4 0.1 9.8e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01002546.1_2 - 3.4e-06 27.3 0.0 5.7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01002546.1_2 - 2e-05 24.5 0.0 3.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AAAP01002546.1_2 - 3.9e-05 23.7 0.0 4.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA PDDEXK_1 PF12705.7 AAAP01002547.1_1 - 7.7e-21 75.1 0.0 2e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Mob_synth_C PF06463.13 AAAP01002549.1_1 - 7.7e-40 135.8 0.0 9.9e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAAP01002549.1_1 - 0.00014 22.3 0.1 0.00022 21.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily YjbR PF04237.13 AAAP01002549.1_1 - 0.17 12.5 0.0 8 7.1 0.0 2.2 2 0 0 2 2 2 0 YjbR MazG PF03819.17 AAAP01002550.1_2 - 1.2e-14 54.3 0.4 1.8e-14 53.7 0.4 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 AAAP01002550.1_2 - 0.00031 20.9 0.1 0.0013 18.9 0.1 2.1 1 1 1 2 2 2 1 MazG-like family PRA-PH PF01503.17 AAAP01002550.1_2 - 0.00036 20.9 0.0 0.00077 19.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Csd3_N PF18059.1 AAAP01002550.1_2 - 0.0069 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Csd3 N-terminal DUF4268 PF14088.6 AAAP01002550.1_2 - 0.15 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) TOBE_2 PF08402.10 AAAP01002551.1_1 - 0.031 14.4 0.4 14 5.9 0.0 3.4 2 1 0 2 2 2 0 TOBE domain DUF2612 PF11041.8 AAAP01002552.1_1 - 1.4e-16 60.9 0.0 1.5e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2612) Baseplate_J PF04865.14 AAAP01002552.1_2 - 2.2e-16 59.8 3.0 7.3e-16 58.1 3.0 1.8 1 1 0 1 1 1 1 Baseplate J-like protein Glu_synthase PF01645.17 AAAP01002553.1_1 - 8.8e-89 298.2 0.5 3.8e-80 269.8 1.0 2.0 2 0 0 2 2 2 2 Conserved region in glutamate synthase FMN_dh PF01070.18 AAAP01002553.1_1 - 1.8e-15 56.8 2.5 1.2e-14 54.1 2.1 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAAP01002553.1_1 - 3.4e-09 36.2 2.3 7.3e-09 35.1 2.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 AAAP01002553.1_1 - 8.8e-08 31.9 8.6 2.7e-07 30.3 7.8 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 AAAP01002553.1_1 - 6.9e-05 22.4 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 AAAP01002553.1_1 - 0.00051 19.3 1.0 0.00091 18.5 1.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 AAAP01002553.1_1 - 0.00072 18.9 1.2 0.0016 17.8 0.5 1.8 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_syn_central PF04898.14 AAAP01002553.1_1 - 0.0044 16.5 0.3 0.0068 15.9 0.3 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain QRPTase_C PF01729.19 AAAP01002553.1_1 - 0.0055 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain LrgB PF04172.16 AAAP01002553.1_1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 LrgB-like family G3P_antiterm PF04309.12 AAAP01002553.1_1 - 0.14 11.5 0.2 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 AAAP01002553.1_1 - 0.18 11.2 2.5 0.26 10.7 0.6 1.9 1 1 1 2 2 2 0 PcrB family HAD_2 PF13419.6 AAAP01002554.1_1 - 5.6e-15 55.9 0.0 6.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01002554.1_1 - 1.5e-08 35.2 0.1 1.9e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01002554.1_1 - 3.8e-07 30.1 0.0 7.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAAP01002554.1_1 - 2.8e-06 27.9 0.4 6.4e-06 26.7 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AAAP01002554.1_1 - 0.015 15.1 0.0 0.67 9.8 0.0 2.1 1 1 0 1 1 1 0 Acid Phosphatase Hydrolase_6 PF13344.6 AAAP01002554.1_1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SmpA_OmlA PF04355.13 AAAP01002554.1_2 - 9.2e-22 76.6 0.3 1.3e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 SmpA / OmlA family CAP_assoc_N PF14504.6 AAAP01002554.1_2 - 0.023 14.5 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 CAP-associated N-terminal LacI PF00356.21 AAAP01002554.1_2 - 0.051 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF3192 PF11399.8 AAAP01002554.1_2 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Ubiq_cyt_C_chap PF03981.12 AAAP01002554.1_3 - 9.9e-11 41.9 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TetR_C_31 PF17940.1 AAAP01002554.1_3 - 0.037 14.2 4.2 0.071 13.3 4.2 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HisKA_2 PF07568.12 AAAP01002555.1_1 - 1.9e-20 72.7 0.0 4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase HWE_HK PF07536.14 AAAP01002555.1_1 - 3.2e-09 37.4 1.2 6.6e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 HWE histidine kinase PAS_9 PF13426.7 AAAP01002555.1_1 - 1e-06 28.9 0.0 3e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 PAS domain HATPase_c_2 PF13581.6 AAAP01002555.1_1 - 1.8e-06 27.9 0.0 4.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AAAP01002555.1_1 - 1.4e-05 25.6 0.0 0.00022 21.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAAP01002555.1_1 - 0.015 15.6 0.0 3.1 8.1 0.0 3.0 3 0 0 3 3 3 0 PAS fold PAS PF00989.25 AAAP01002555.1_1 - 0.03 14.3 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 PAS fold DUF349 PF03993.12 AAAP01002555.1_1 - 0.038 14.3 0.4 0.077 13.3 0.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) PAS_4 PF08448.10 AAAP01002555.1_1 - 0.063 13.5 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 PAS fold AMP-binding_C_2 PF14535.6 AAAP01002555.1_1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SAPIS-gp6 PF16722.5 AAAP01002555.1_1 - 0.18 12.2 0.7 0.29 11.6 0.2 1.6 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Response_reg PF00072.24 AAAP01002555.1_2 - 1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain NTP_transf_2 PF01909.23 AAAP01002556.1_2 - 0.1 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase domain Hydrolase PF00702.26 AAAP01002556.1_3 - 8.4e-45 153.6 6.0 1.1e-44 153.3 6.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01002556.1_3 - 1.1e-06 28.6 0.6 0.0026 17.6 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01002556.1_3 - 0.00017 22.1 0.7 0.0016 18.9 0.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01002556.1_3 - 0.018 15.2 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4350 PF14258.6 AAAP01002556.1_3 - 0.03 14.7 1.0 1 9.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4350) DUF11 PF01345.18 AAAP01002557.1_1 - 8.7 6.7 21.6 0.034 14.4 3.2 3.9 3 1 1 4 4 4 0 Domain of unknown function DUF11 ParD_antitoxin PF03693.14 AAAP01002558.1_2 - 1e-06 29.1 0.1 1.4e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH RHH_1 PF01402.21 AAAP01002558.1_2 - 2.1e-05 24.3 1.5 2.5e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family TilS PF09179.11 AAAP01002558.1_2 - 0.016 15.7 4.6 0.016 15.6 2.2 1.9 1 1 1 2 2 2 0 TilS substrate binding domain DUF469 PF04320.14 AAAP01002558.1_2 - 0.071 14.0 0.0 0.09 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein with unknown function (DUF469) ParE_toxin PF05016.15 AAAP01002558.1_3 - 5e-13 49.5 0.3 6.2e-13 49.2 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Fur_reg_FbpB PF13040.6 AAAP01002558.1_3 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Fur-regulated basic protein B Aldo_ket_red PF00248.21 AAAP01002558.1_4 - 2.3e-22 79.6 0.0 2.8e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 AAAP01002559.1_1 - 1.3e-15 57.8 32.6 2.2e-11 44.1 14.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF2626 PF11117.8 AAAP01002559.1_1 - 6.7 7.5 7.6 3.5 8.4 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2626) MerR_1 PF13411.6 AAAP01002560.1_1 - 2.9e-14 52.9 0.0 5.8e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01002560.1_1 - 4.7e-13 48.7 0.4 1.3e-12 47.2 0.4 1.8 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AAAP01002560.1_1 - 0.00047 20.6 1.0 0.00097 19.6 0.9 1.6 1 1 0 1 1 1 1 MerR, DNA binding HTH_31 PF13560.6 AAAP01002560.1_1 - 0.01 16.2 2.3 0.012 16.0 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 AAAP01002560.1_1 - 0.026 14.7 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 AAAP01002560.1_2 - 1.9e-21 76.5 0.0 2.1e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Gln-synt_C PF00120.24 AAAP01002561.1_1 - 1.3e-135 451.9 0.0 1.5e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAAP01002561.1_1 - 4.9e-31 106.3 1.0 1.1e-30 105.2 1.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF3148 PF11347.8 AAAP01002562.1_1 - 0.086 12.6 0.0 1.8 8.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3148) HTH_17 PF12728.7 AAAP01002562.1_3 - 3.9e-07 30.2 0.1 4.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 AAAP01002562.1_3 - 0.02 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein MerR_1 PF13411.6 AAAP01002562.1_3 - 0.046 13.8 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein Fer2_BFD PF04324.15 AAAP01002564.1_1 - 2.5e-13 50.2 3.3 4.3e-13 49.4 3.3 1.4 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Molydop_binding PF01568.21 AAAP01002564.1_1 - 8.7e-11 41.8 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Sigma70_r2 PF04542.14 AAAP01002565.1_1 - 0.00017 21.3 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 NepR PF18557.1 AAAP01002565.1_1 - 0.0018 17.8 1.0 0.0039 16.8 1.0 1.5 1 0 0 1 1 1 1 Anti-sigma factor NepR NUC130_3NT PF08158.12 AAAP01002565.1_1 - 0.0076 16.6 0.1 0.029 14.7 0.2 2.0 1 1 0 1 1 1 1 NUC130/3NT domain SCAB_CC PF16712.5 AAAP01002565.1_1 - 0.055 13.3 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein MscL PF01741.18 AAAP01002565.1_2 - 1.5e-44 151.1 1.0 1.7e-44 151.0 1.0 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Gly-zipper_Omp PF13488.6 AAAP01002565.1_2 - 0.87 9.6 11.8 0.36 10.9 6.2 2.2 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 AAAP01002565.1_2 - 0.9 9.3 10.7 0.43 10.4 5.9 2.3 2 1 0 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 AAAP01002565.1_2 - 7 6.8 9.5 2.8 8.1 5.2 2.1 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide SGTA_dimer PF16546.5 AAAP01002565.1_3 - 0.058 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Homodimerisation domain of SGTA Tautomerase_2 PF14552.6 AAAP01002566.1_1 - 2.3e-31 107.7 0.0 3.3e-30 104.0 0.0 1.9 1 1 1 2 2 2 1 Tautomerase enzyme Tautomerase PF01361.21 AAAP01002566.1_1 - 2.5e-14 52.9 0.0 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme LysR_substrate PF03466.20 AAAP01002566.1_2 - 7.1e-20 71.3 1.7 7.9e-20 71.1 1.7 1.0 1 0 0 1 1 1 1 LysR substrate binding domain KaiB PF07689.12 AAAP01002566.1_2 - 0.044 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiB domain HTH_Crp_2 PF13545.6 AAAP01002567.1_2 - 1.4e-12 47.4 1.3 2.8e-12 46.4 1.3 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01002567.1_2 - 3.3e-05 23.9 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GntR PF00392.21 AAAP01002567.1_2 - 0.035 13.8 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_CodY PF08222.11 AAAP01002567.1_2 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Chorismate_bind PF00425.18 AAAP01002568.1_1 - 7.6e-67 225.6 0.0 9.9e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAAP01002568.1_1 - 1.2e-21 77.4 0.0 3.3e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region dCache_1 PF02743.18 AAAP01002569.1_1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.6 1 1 0 1 1 1 1 Cache domain LPD30 PF18850.1 AAAP01002569.1_1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 ATP-synt_ab_C PF00306.27 AAAP01002570.1_1 - 1.9e-38 131.6 0.1 2.3e-38 131.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt PF00231.19 AAAP01002570.1_2 - 1.4e-91 307.1 1.1 1.5e-91 307.0 1.1 1.0 1 0 0 1 1 1 1 ATP synthase acVLRF1 PF18859.1 AAAP01002570.1_2 - 0.068 13.5 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor HTH_Tnp_Mu_2 PF09039.11 AAAP01002570.1_2 - 0.19 11.8 1.0 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain ATP-synt_ab_N PF02874.23 AAAP01002570.1_3 - 2.6e-23 82.3 1.2 4.4e-23 81.6 1.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 AAAP01002570.1_3 - 3.6e-08 33.3 0.3 1.2e-07 31.6 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 AAAP01002570.1_3 - 0.04 14.3 0.1 0.075 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAAP01002570.1_3 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain RnfC_N PF13375.6 AAAP01002570.1_3 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NACHT PF05729.12 AAAP01002570.1_3 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MethyltransfD12 PF02086.15 AAAP01002571.1_2 - 0.0065 16.2 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TP_methylase PF00590.20 AAAP01002572.1_1 - 1.4e-46 159.1 3.2 2.1e-46 158.5 3.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CysG_dimeriser PF10414.9 AAAP01002572.1_1 - 5e-08 32.5 4.9 5e-08 32.5 4.9 2.0 2 0 0 2 2 2 1 Sirohaem synthase dimerisation region NAD_binding_7 PF13241.6 AAAP01002572.1_1 - 1.8e-06 28.4 0.0 6.2e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 AAAP01002572.1_1 - 3.5e-05 23.2 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ABC_tran PF00005.27 AAAP01002573.1_1 - 1.4e-35 122.8 0.0 2.2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAAP01002573.1_1 - 1e-20 74.6 0.6 1.3e-20 74.2 0.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAAP01002573.1_1 - 9.1e-06 25.3 0.0 0.00027 20.5 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01002573.1_1 - 9.8e-05 22.8 1.1 0.00046 20.6 1.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01002573.1_1 - 0.00023 21.4 0.1 0.0033 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01002573.1_1 - 0.001 18.9 0.0 0.0098 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 AAAP01002573.1_1 - 0.0024 16.8 0.0 0.0057 15.5 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 AAAP01002573.1_1 - 0.0027 17.4 0.0 0.01 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01002573.1_1 - 0.0029 18.0 0.1 0.04 14.4 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01002573.1_1 - 0.015 15.3 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AAAP01002573.1_1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01002573.1_1 - 0.023 14.0 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 AAAP01002573.1_1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01002573.1_1 - 0.027 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AAAP01002573.1_1 - 0.028 14.6 0.3 0.075 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01002573.1_1 - 0.038 13.6 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAAP01002573.1_1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 AAAP01002573.1_1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01002573.1_1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Cuticle_1 PF08140.11 AAAP01002573.1_1 - 0.17 11.9 0.4 4 7.6 0.1 2.7 2 0 0 2 2 2 0 Crustacean cuticle protein repeat NTPase_1 PF03266.15 AAAP01002573.1_1 - 0.22 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 NTPase SbcCD_C PF13558.6 AAAP01002573.1_1 - 7.2 6.9 8.7 2.1 8.7 1.4 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 AAAP01002573.1_2 - 7.9e-07 29.0 0.0 8.5e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Peripla_BP_2 PF01497.18 AAAP01002574.1_1 - 6.7e-11 42.2 0.0 7.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein MmcB-like PF06319.12 AAAP01002574.1_2 - 3.6e-37 127.3 0.1 4.2e-37 127.1 0.1 1.1 1 0 0 1 1 1 1 DNA repair protein MmcB-like RHH_4 PF13467.6 AAAP01002574.1_3 - 7.2e-27 93.1 0.6 8.8e-27 92.8 0.6 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix domain RHH_1 PF01402.21 AAAP01002574.1_3 - 0.0021 18.0 0.6 0.015 15.2 0.0 2.2 1 1 1 2 2 2 1 Ribbon-helix-helix protein, copG family Ribonucleas_3_3 PF14622.6 AAAP01002574.1_3 - 0.095 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like DUF4169 PF13770.6 AAAP01002574.1_4 - 1e-20 73.7 9.9 1.1e-20 73.6 9.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4169) Cir_N PF10197.9 AAAP01002574.1_4 - 0.83 9.9 8.5 0.53 10.5 3.3 2.1 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Thioredoxin_4 PF13462.6 AAAP01002575.1_1 - 2.9e-39 134.9 0.0 3.9e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AAAP01002575.1_1 - 4e-11 43.1 0.0 1.4e-05 25.0 0.0 2.0 1 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 AAAP01002575.1_1 - 0.005 16.9 0.0 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin PF00085.20 AAAP01002575.1_1 - 0.008 16.1 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AAAP01002575.1_1 - 0.0084 16.5 0.1 0.17 12.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Form_Nir_trans PF01226.17 AAAP01002575.1_2 - 0.012 15.0 1.0 0.013 14.8 1.0 1.0 1 0 0 1 1 1 0 Formate/nitrite transporter ECF-ribofla_trS PF07155.12 AAAP01002575.1_2 - 0.25 11.3 3.5 0.32 11.0 3.5 1.1 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component GCS2 PF04107.13 AAAP01002576.1_2 - 2.3e-14 53.4 0.7 2.5e-14 53.3 0.7 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) GCS PF03074.16 AAAP01002576.1_2 - 0.072 12.4 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase KH_dom-like PF14714.6 AAAP01002576.1_4 - 3.3e-14 52.9 0.1 6.9e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 AAAP01002576.1_4 - 7.9e-07 28.8 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAAP01002576.1_4 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01002576.1_4 - 0.01 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B BPD_transp_2 PF02653.16 AAAP01002577.1_2 - 8.8e-16 57.9 14.1 8.8e-16 57.9 14.1 2.0 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component tRNA-synt_1 PF00133.22 AAAP01002578.1_1 - 1.2e-115 387.1 0.0 1.4e-115 386.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01002578.1_1 - 5e-08 32.1 0.0 3.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 AAAP01002578.1_1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AAAP01002578.1_1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 AAAP01002578.1_1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) OppC_N PF12911.7 AAAP01002579.1_2 - 1.9e-07 30.9 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C MadM PF03818.13 AAAP01002579.1_2 - 0.037 13.9 0.2 0.047 13.5 0.2 1.2 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit BPD_transp_1 PF00528.22 AAAP01002579.1_3 - 7.2e-34 117.1 13.8 1.3e-33 116.3 13.8 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Trep_Strep PF09605.10 AAAP01002579.1_3 - 0.02 14.8 4.0 0.02 14.8 4.0 1.9 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Laminin_G_3 PF13385.6 AAAP01002580.1_1 - 1.2e-09 38.5 0.0 1.6e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily PsaD PF02531.16 AAAP01002581.1_1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 PsaD ABC_tran PF00005.27 AAAP01002581.1_2 - 2.7e-11 44.1 0.0 4.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01002581.1_2 - 5.3e-06 26.0 0.0 6.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAAP01002581.1_2 - 0.013 15.8 0.1 0.16 12.2 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DAHP_synth_2 PF01474.16 AAAP01002582.1_1 - 2.1e-93 313.2 0.0 2.5e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF2620 PF10941.8 AAAP01002582.1_3 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2620 TetR_C_33 PF13305.6 AAAP01002583.1_2 - 9.4e-16 58.4 5.0 9.4e-16 58.4 5.0 2.2 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAAP01002583.1_2 - 0.00016 21.4 0.4 0.0004 20.1 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Hydrolase_6 PF13344.6 AAAP01002583.1_3 - 4.8e-09 36.2 0.0 6.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 AAAP01002584.1_2 - 0.0051 16.7 0.0 0.0081 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002584.1_2 - 0.0095 16.6 0.0 0.028 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002584.1_2 - 0.013 16.1 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain EPSP_synthase PF00275.20 AAAP01002585.1_1 - 1.2e-08 34.1 0.2 1.2e-08 34.1 0.2 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) EspF PF04806.12 AAAP01002585.1_2 - 0.031 14.7 3.2 0.045 14.1 3.2 1.2 1 0 0 1 1 1 0 EspF protein repeat Aminotran_1_2 PF00155.21 AAAP01002585.1_3 - 2.6e-56 191.4 0.0 3e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01002585.1_3 - 3.9e-05 22.4 0.0 5.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAAP01002585.1_3 - 0.00097 18.5 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AAAP01002585.1_3 - 0.0077 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_1 PF00561.20 AAAP01002586.1_1 - 2.1e-24 86.5 0.1 2.9e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01002586.1_1 - 0.052 12.8 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BCSC_C PF05420.11 AAAP01002586.1_1 - 0.068 12.3 0.1 0.098 11.8 0.1 1.1 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Acetyltransf_1 PF00583.25 AAAP01002586.1_2 - 2.3e-06 27.8 0.0 2.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AAAP01002586.1_2 - 0.00013 22.1 0.0 0.00036 20.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01002586.1_2 - 0.00022 21.6 0.0 0.00029 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01002586.1_2 - 0.0032 17.4 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01002586.1_2 - 0.051 13.5 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 AAAP01002586.1_2 - 0.17 11.6 0.1 0.85 9.4 0.1 1.9 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ CstA PF02554.14 AAAP01002587.1_1 - 2.7e-96 322.7 12.9 3.4e-96 322.4 12.9 1.0 1 0 0 1 1 1 1 Carbon starvation protein CstA DUF5527 PF17665.1 AAAP01002587.1_1 - 0.19 11.3 0.6 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5527) ACR_tran PF00873.19 AAAP01002587.1_1 - 4 4.9 8.8 6.3 4.3 8.8 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF442 PF04273.13 AAAP01002588.1_3 - 0.061 13.4 0.0 0.52 10.4 0.1 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DHO_dh PF01180.21 AAAP01002589.1_1 - 1.3e-30 106.6 0.0 1.5e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Molybdopterin PF00384.22 AAAP01002589.1_2 - 8.3e-15 54.7 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase DUF5619 PF18505.1 AAAP01002589.1_2 - 0.07 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) CBM65_1 PF18259.1 AAAP01002589.1_2 - 0.19 11.9 0.1 0.85 9.8 0.0 2.1 3 0 0 3 3 3 0 Carbohydrate binding module 65 domain 1 HATPase_c PF02518.26 AAAP01002590.1_1 - 1.4e-09 38.5 0.0 2.9e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01002590.1_1 - 1.3e-08 34.8 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PQQ_3 PF13570.6 AAAP01002590.1_3 - 0.01 16.3 1.4 0.012 16.0 0.4 1.7 2 0 0 2 2 2 0 PQQ-like domain Transgly PF00912.22 AAAP01002591.1_1 - 1.6e-60 203.6 0.0 2.5e-60 203.0 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AAAP01002591.1_1 - 1.9e-14 53.6 0.0 3.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain DHDPS PF00701.22 AAAP01002592.1_2 - 1.9e-89 299.2 0.0 2.1e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 AAAP01002592.1_2 - 0.001 19.0 1.1 0.0017 18.3 0.3 1.8 2 0 0 2 2 2 1 PA domain Amidohydro_2 PF04909.14 AAAP01002592.1_2 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase PEP_mutase PF13714.6 AAAP01002592.1_2 - 0.0066 15.9 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.16 AAAP01002593.1_2 - 1.5e-31 109.7 82.7 1.1e-28 100.3 49.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01002593.1_2 - 1.6e-07 31.0 40.7 2.4e-07 30.4 40.7 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Peptidase_M15_2 PF05951.13 AAAP01002594.1_1 - 1.7e-20 73.3 0.3 2.6e-20 72.6 0.3 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) DUF2076 PF09849.9 AAAP01002594.1_1 - 0.031 14.3 0.2 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2312 PF10073.9 AAAP01002594.1_2 - 4.7e-36 122.3 5.7 5.3e-36 122.1 5.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) MerR-DNA-bind PF09278.11 AAAP01002594.1_2 - 0.0024 18.4 0.4 2.1 9.0 0.0 2.2 2 0 0 2 2 2 2 MerR, DNA binding DUF1810 PF08837.11 AAAP01002595.1_3 - 7.3e-51 171.5 0.0 9e-51 171.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) Alpha-amylase PF00128.24 AAAP01002596.1_2 - 2.6e-46 158.7 0.0 3e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Lactamase_B PF00753.27 AAAP01002597.1_1 - 9.1e-14 51.9 0.1 1.3e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01002597.1_1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NTP_transferase PF00483.23 AAAP01002598.1_1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AAAP01002598.1_1 - 0.0023 17.6 1.4 0.033 13.9 0.2 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) HAD PF12710.7 AAAP01002598.1_2 - 3.5e-27 96.0 0.7 4.6e-27 95.7 0.7 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01002598.1_2 - 1.1e-15 58.5 2.0 1.7e-15 57.9 2.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01002598.1_2 - 8e-10 38.9 0.1 3.3e-09 36.9 0.0 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAAP01002598.1_2 - 0.00056 19.5 0.1 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 AAAP01002598.1_2 - 0.0014 18.8 0.0 1 9.4 0.1 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AAAP01002598.1_2 - 0.004 16.6 0.0 0.041 13.3 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase_like PF13242.6 AAAP01002598.1_2 - 0.06 13.4 2.7 1 9.5 0.7 2.4 2 0 0 2 2 2 0 HAD-hyrolase-like DFP PF04127.15 AAAP01002598.1_2 - 0.067 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HNH_repeat PF18780.1 AAAP01002598.1_2 - 4.9 7.0 5.1 3.8 7.4 0.3 2.8 2 0 0 2 2 2 0 Homing endonuclease repeat RMMBL PF07521.12 AAAP01002598.1_3 - 0.031 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain DDE_Tnp_ISL3 PF01610.17 AAAP01002599.1_1 - 1.6e-49 168.8 0.1 1.8e-49 168.7 0.1 1.0 1 0 0 1 1 1 1 Transposase Lum_binding PF00677.17 AAAP01002600.1_1 - 1.7e-48 162.5 0.1 1e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Metallophos_2 PF12850.7 AAAP01002600.1_1 - 0.043 14.0 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RibD_C PF01872.17 AAAP01002600.1_2 - 1.9e-47 161.7 0.4 2.7e-47 161.2 0.4 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAAP01002600.1_2 - 6.1e-10 38.9 0.1 1.4e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAAP01002600.1_2 - 3.7e-05 23.5 0.1 6.9e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Nitro_FeMo-Co PF02579.17 AAAP01002600.1_2 - 0.0039 17.5 1.0 3.2 8.2 0.2 2.7 2 0 0 2 2 2 2 Dinitrogenase iron-molybdenum cofactor SIMPL PF04402.14 AAAP01002601.1_1 - 6.1e-14 52.9 0.2 7.5e-14 52.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) ArgJ PF01960.18 AAAP01002601.1_2 - 1.5e-75 254.3 0.7 1.7e-75 254.1 0.7 1.0 1 0 0 1 1 1 1 ArgJ family GlgX_C PF18390.1 AAAP01002602.1_1 - 0.043 13.6 0.1 0.71 9.7 0.0 2.4 3 0 0 3 3 3 0 Glycogen debranching enzyme C-terminal domain AAA_26 PF13500.6 AAAP01002603.1_1 - 4.3e-07 30.0 0.0 5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain Response_reg PF00072.24 AAAP01002603.1_3 - 2.2e-13 50.3 0.0 2.6e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain adh_short PF00106.25 AAAP01002603.1_3 - 0.037 13.5 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Molydop_binding PF01568.21 AAAP01002604.1_1 - 1e-21 77.0 0.0 1.7e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdopterin PF00384.22 AAAP01002604.1_1 - 3.3e-13 49.4 0.0 4.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase TatD_DNase PF01026.21 AAAP01002605.1_1 - 2.9e-15 56.3 0.0 3.2e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Lactamase_B_2 PF12706.7 AAAP01002605.1_2 - 5e-17 62.1 0.0 6.2e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Creatininase PF02633.14 AAAP01002606.1_1 - 1.4e-17 64.0 0.0 1.5e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Abhydrolase_6 PF12697.7 AAAP01002606.1_2 - 0.0012 19.5 6.7 0.0012 19.5 6.7 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01002606.1_2 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAAP01002606.1_2 - 0.056 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 AAAP01002606.1_2 - 0.2 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2842 PF11003.8 AAAP01002606.1_2 - 1.1 9.6 8.6 2.8 8.2 8.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) FliL PF03748.14 AAAP01002608.1_1 - 1.7e-18 67.1 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL DUF4366 PF14283.6 AAAP01002608.1_1 - 0.0054 16.8 0.3 0.0081 16.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) RskA PF10099.9 AAAP01002608.1_1 - 0.094 13.0 0.5 0.13 12.6 0.4 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PLA2_B PF01735.18 AAAP01002608.1_2 - 0.12 10.8 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 Lysophospholipase catalytic domain FliN_N PF16973.5 AAAP01002608.1_2 - 0.36 10.7 9.4 2.6 7.9 3.5 2.2 1 1 1 2 2 2 0 Flagellar motor switch protein FliN N-terminal DUF802 PF05650.11 AAAP01002608.1_2 - 1.6 9.3 11.7 0.79 10.2 1.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF802) FhuF PF06276.12 AAAP01002609.1_1 - 1.1e-32 113.7 0.8 1.4e-32 113.4 0.8 1.1 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter TetR_C_30 PF17939.1 AAAP01002609.1_1 - 0.05 13.8 0.7 2 8.6 0.2 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Penicil_amidase PF01804.18 AAAP01002609.1_2 - 5.3e-15 55.5 0.5 5.8e-15 55.3 0.5 1.0 1 0 0 1 1 1 1 Penicillin amidase FecCD PF01032.18 AAAP01002610.1_2 - 1.9e-91 306.4 33.6 2.2e-91 306.1 33.6 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AAAP01002610.1_2 - 0.00032 20.3 8.0 0.00047 19.7 7.4 1.6 1 1 0 1 1 1 1 ABC 3 transport family ABC_tran PF00005.27 AAAP01002610.1_3 - 8.1e-12 45.8 0.0 9.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002610.1_3 - 8.7e-05 22.5 0.0 8.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 AAAP01002610.1_3 - 0.00032 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01002610.1_3 - 0.00065 19.5 0.0 0.0009 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01002610.1_3 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01002610.1_3 - 0.0012 19.3 0.0 0.0014 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAAP01002610.1_3 - 0.0013 19.3 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01002610.1_3 - 0.0018 17.9 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AAAP01002610.1_3 - 0.0045 16.9 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 AAAP01002610.1_3 - 0.012 15.9 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01002610.1_3 - 0.015 15.4 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 AAAP01002610.1_3 - 0.024 14.8 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAAP01002610.1_3 - 0.03 14.0 0.0 0.036 13.8 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 AAAP01002610.1_3 - 0.031 14.2 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 AAAP01002610.1_3 - 0.032 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AAAP01002610.1_3 - 0.043 12.5 0.0 0.05 12.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01002610.1_3 - 0.046 13.0 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 AAAP01002610.1_3 - 0.059 13.9 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AAAP01002610.1_3 - 0.068 12.0 0.0 0.079 11.7 0.0 1.0 1 0 0 1 1 1 0 Adenovirus IVa2 protein NACHT PF05729.12 AAAP01002610.1_3 - 0.087 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 AAAP01002610.1_3 - 0.098 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein CLP1_P PF16575.5 AAAP01002610.1_3 - 0.19 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 AAAP01002610.1_3 - 0.2 11.9 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAAP01002610.1_3 - 0.21 11.6 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01002610.1_3 - 0.23 11.9 0.0 0.3 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA helicase DUF3584 PF12128.8 AAAP01002610.1_3 - 0.3 8.5 0.0 0.37 8.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4054 PF13262.6 AAAP01002611.1_2 - 1.6e-27 95.6 0.1 1.8e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4054) Glyco_transf_9 PF01075.17 AAAP01002612.1_2 - 1.2e-22 80.4 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_4 PF13439.6 AAAP01002612.1_2 - 0.0048 16.9 6.5 0.45 10.5 0.9 2.8 2 1 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01002612.1_2 - 4 7.9 39.3 0.045 14.2 11.7 3.7 1 1 2 3 3 3 0 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 AAAP01002612.1_3 - 9e-10 38.3 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01002612.1_3 - 1.1e-08 35.3 0.1 2e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01002612.1_3 - 3e-07 30.9 0.0 5.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01002612.1_4 - 1.7e-09 37.9 0.3 1.8e-09 37.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01002612.1_4 - 1.9e-07 31.6 2.4 2.2e-07 31.4 2.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Gemin7 PF11095.8 AAAP01002612.1_4 - 0.009 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Glyco_transf_5 PF08323.11 AAAP01002612.1_4 - 0.022 14.4 0.1 0.023 14.4 0.1 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 AAAP01002612.1_4 - 0.21 11.6 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like Formyl_trans_N PF00551.19 AAAP01002613.1_2 - 4.7e-37 127.5 0.0 5.3e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Pep_deformylase PF01327.21 AAAP01002613.1_3 - 5.8e-52 175.5 0.0 6.6e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase adh_short PF00106.25 AAAP01002613.1_5 - 0.00016 21.2 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase OKR_DC_1 PF01276.20 AAAP01002614.1_1 - 1.2e-47 162.6 0.0 1.5e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_N PF03709.15 AAAP01002614.1_1 - 4.8e-28 97.7 0.0 6.9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Beta_elim_lyase PF01212.21 AAAP01002614.1_1 - 0.0033 16.7 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase NDK PF00334.19 AAAP01002614.1_1 - 0.074 13.1 0.0 5.4 7.0 0.0 2.4 3 0 0 3 3 3 0 Nucleoside diphosphate kinase FtsK_SpoIIIE PF01580.18 AAAP01002614.1_1 - 0.084 12.2 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Response_reg PF00072.24 AAAP01002614.1_1 - 0.093 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Response regulator receiver domain CobN-Mg_chel PF02514.16 AAAP01002615.1_1 - 2.3e-60 204.5 0.0 2.8e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 AAAP01002615.1_1 - 7.2e-17 62.0 0.0 1.2e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) OsmC PF02566.19 AAAP01002616.1_1 - 1.8e-14 54.1 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein FAM193_C PF15914.5 AAAP01002616.1_1 - 0.049 13.4 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 FAM193 family C-terminal SnoaL_2 PF12680.7 AAAP01002616.1_2 - 2.6e-05 24.8 0.2 3.7e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AAAP01002616.1_2 - 0.0025 18.2 0.2 0.0036 17.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 AAAP01002616.1_2 - 0.0078 16.8 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 AAAP01002616.1_2 - 0.045 13.9 0.1 0.067 13.3 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF2778 PF10908.8 AAAP01002616.1_3 - 9.5e-09 35.6 0.0 1.1e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2778) FtsH_ext PF06480.15 AAAP01002616.1_3 - 0.12 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 FtsH Extracellular Response_reg PF00072.24 AAAP01002617.1_1 - 1.1e-20 73.8 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HTH_3 PF01381.22 AAAP01002618.1_1 - 2.2e-05 24.4 0.3 3.7e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01002618.1_1 - 0.00065 20.0 0.1 0.001 19.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01002618.1_1 - 0.065 13.3 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain XdhC_C PF13478.6 AAAP01002619.1_1 - 9e-20 71.4 0.0 1.4e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AAAP01002619.1_2 - 7.6e-28 96.5 0.8 1.1e-27 96.0 0.8 1.2 1 0 0 1 1 1 1 XdhC and CoxI family Peripla_BP_6 PF13458.6 AAAP01002619.1_3 - 1.7e-17 64.1 0.2 1.8e-17 64.0 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01002619.1_3 - 1.7e-08 33.8 0.0 2e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01002619.1_3 - 1.6e-06 27.5 0.0 1.7e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region ACR_tran PF00873.19 AAAP01002620.1_1 - 8.1e-60 202.6 4.0 9.7e-60 202.3 4.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01002620.1_1 - 0.00034 19.7 12.9 0.0011 17.9 12.9 1.7 1 1 0 1 1 1 1 MMPL family DUF305 PF03713.13 AAAP01002620.1_3 - 1.3e-15 57.9 19.1 2.9e-14 53.5 18.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 AAAP01002620.1_3 - 1.2e-05 25.6 1.2 1.2e-05 25.6 1.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4142) Ferritin PF00210.24 AAAP01002620.1_3 - 1.4e-05 25.1 0.3 2.5e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Ferritin-like domain DUF2383 PF09537.10 AAAP01002620.1_3 - 0.0017 18.7 0.7 0.008 16.5 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) Methyltransf_11 PF08241.12 AAAP01002621.1_1 - 7.8e-05 23.3 0.0 9.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002621.1_1 - 8e-05 23.3 0.0 0.0001 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Response_reg PF00072.24 AAAP01002622.1_2 - 3.4e-05 24.0 0.0 4.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain YkuD PF03734.14 AAAP01002622.1_3 - 3.1e-06 27.7 0.1 5e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Lipase_GDSL_2 PF13472.6 AAAP01002623.1_1 - 2e-15 57.6 0.2 2.4e-15 57.4 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAAP01002623.1_1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Toprim_3 PF13362.6 AAAP01002623.1_1 - 0.029 14.7 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Toprim domain DJ-1_PfpI PF01965.24 AAAP01002623.1_2 - 3.8e-31 108.1 0.1 5e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family RuvX PF03652.15 AAAP01002623.1_3 - 1.1e-09 38.8 0.1 1.2e-09 38.7 0.1 1.1 1 0 0 1 1 1 1 Holliday junction resolvase UbiA PF01040.18 AAAP01002624.1_1 - 5e-38 130.8 16.7 5e-38 130.8 16.7 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family HXXEE PF13787.6 AAAP01002624.1_1 - 0.18 12.6 7.2 2.5 8.9 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif LapA_dom PF06305.11 AAAP01002624.1_1 - 0.78 9.6 6.4 0.21 11.4 2.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PUCC PF03209.15 AAAP01002624.1_2 - 1.3e-77 261.5 34.7 1.5e-77 261.3 34.7 1.0 1 0 0 1 1 1 1 PUCC protein MFS_1 PF07690.16 AAAP01002624.1_2 - 4.2e-11 42.4 56.0 6.5e-11 41.8 56.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 AAAP01002624.1_2 - 0.24 10.8 2.8 1.8 8.0 2.5 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF411 PF04214.13 AAAP01002625.1_1 - 4e-32 110.0 1.2 6e-32 109.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF Hydrolase PF00702.26 AAAP01002625.1_3 - 8.1e-44 150.4 8.7 1e-43 150.1 8.7 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01002625.1_3 - 8.9e-09 35.4 0.3 0.00011 22.0 0.4 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01002625.1_3 - 3.7e-06 27.5 0.2 4.4e-05 24.0 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01002625.1_3 - 0.00099 19.2 0.1 0.0042 17.2 0.0 2.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 AAAP01002625.1_3 - 0.053 13.4 0.0 2.2 8.2 0.0 2.8 3 1 0 3 3 3 0 AhpC/TSA family IF-2 PF11987.8 AAAP01002626.1_1 - 3.6e-37 126.7 0.2 5.8e-37 126.0 0.2 1.3 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 AAAP01002626.1_1 - 3.5e-06 27.3 1.4 9.4e-05 22.7 0.1 3.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GATase_3 PF07685.14 AAAP01002627.1_2 - 5.9e-30 104.3 0.0 7.3e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 AAAP01002627.1_2 - 8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01002627.1_2 - 0.00026 21.0 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 AAAP01002627.1_2 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DSBA PF01323.20 AAAP01002628.1_1 - 0.11 12.2 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DEDD_Tnp_IS110 PF01548.17 AAAP01002628.1_2 - 0.0028 17.5 0.0 0.0031 17.4 0.0 1.0 1 0 0 1 1 1 1 Transposase p450 PF00067.22 AAAP01002628.1_4 - 6.1e-32 111.0 0.1 1e-29 103.6 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_MocR PF12897.7 AAAP01002629.1_1 - 2.5e-66 224.2 0.0 3e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_MocR PF12897.7 AAAP01002629.1_2 - 1.5e-69 234.9 0.5 1.6e-69 234.7 0.5 1.0 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase UvrD_C_2 PF13538.6 AAAP01002629.1_3 - 3.4e-19 68.4 1.4 5.3e-19 67.8 1.4 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 AAAP01002629.1_3 - 0.00033 20.5 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 AAAP01002629.1_3 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain HMGL-like PF00682.19 AAAP01002630.1_1 - 3.3e-66 223.5 0.0 4.2e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 HMGL-like MOSC_N PF03476.16 AAAP01002631.1_1 - 1.9e-05 24.5 0.0 1.9e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Clp_N PF02861.20 AAAP01002631.1_2 - 7.8e-23 80.4 4.3 5.6e-13 48.8 0.9 2.3 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AAAP01002631.1_2 - 2.6e-06 27.9 2.9 3.6e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AAAP01002631.1_2 - 0.018 15.0 0.2 0.062 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAAP01002631.1_2 - 0.026 14.8 0.1 0.12 12.7 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 AAAP01002631.1_2 - 0.029 14.8 0.1 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PCP_red PF08369.10 AAAP01002631.1_2 - 0.043 14.0 0.6 0.27 11.5 0.1 2.4 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit IstB_IS21 PF01695.17 AAAP01002631.1_2 - 0.061 13.0 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 AAAP01002631.1_2 - 0.098 12.9 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 AAAP01002631.1_2 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Phyto_Pns9_10 PF05878.11 AAAP01002631.1_2 - 0.17 11.0 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Aa_trans PF01490.18 AAAP01002632.1_1 - 0.012 14.4 0.5 0.014 14.1 0.5 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein PAS_3 PF08447.12 AAAP01002632.1_2 - 2.8e-15 56.4 0.0 5.2e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold GAF_2 PF13185.6 AAAP01002632.1_2 - 2.3e-11 44.1 0.1 5.9e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AAAP01002632.1_2 - 3.9e-11 43.7 0.3 6.5e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAAP01002632.1_2 - 6.4e-07 29.8 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 AAAP01002632.1_2 - 9.8e-07 28.8 0.0 0.0067 16.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01002632.1_2 - 5.1e-06 26.7 3.9 0.00017 21.8 0.1 2.9 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01002632.1_2 - 0.00027 21.2 0.0 0.0067 16.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AAAP01002632.1_2 - 0.00086 19.3 0.0 0.016 15.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain MPTase-PolyVal PF18818.1 AAAP01002633.1_1 - 2.5e-10 40.5 0.0 3.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase superfamily domain BPD_transp_2 PF02653.16 AAAP01002634.1_1 - 9e-07 28.3 9.0 9e-07 28.3 9.0 1.7 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01002634.1_2 - 3.7e-18 65.6 29.8 4.5e-18 65.4 29.8 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AAAP01002634.1_3 - 8.8e-25 87.8 0.0 1.2e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01002634.1_3 - 2.8e-09 36.7 0.6 4.6e-09 36.0 0.6 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAAP01002634.1_3 - 0.041 13.7 0.0 8.4 6.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ROS_MUCR PF05443.11 AAAP01002635.1_1 - 5.3e-23 81.4 0.1 9.5e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein TonB_N PF16031.5 AAAP01002635.1_1 - 0.00034 21.1 5.5 0.00043 20.8 5.5 1.3 1 0 0 1 1 1 1 TonB polyproline region Trypan_PARP PF05887.11 AAAP01002635.1_1 - 0.037 14.0 6.7 0.049 13.6 6.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABC_tran PF00005.27 AAAP01002636.1_1 - 2.7e-09 37.6 0.0 3.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 AAAP01002636.1_1 - 0.16 12.2 0.5 3.8 7.8 0.5 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 AAAP01002636.1_2 - 2.9e-28 99.1 0.0 7.2e-28 97.8 0.0 1.7 1 1 0 1 1 1 1 ABC transporter ABC_tran_Xtn PF12848.7 AAAP01002636.1_2 - 1.7e-12 47.2 0.8 1.7e-12 47.2 0.8 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAAP01002636.1_2 - 2.8e-06 27.4 6.6 0.0077 16.1 0.4 2.7 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 AAAP01002636.1_2 - 0.0015 17.2 0.0 0.51 8.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 AAAP01002636.1_2 - 0.0021 17.5 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01002636.1_2 - 0.1 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 AAAP01002636.1_2 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Dynamin family DUF2213 PF09979.9 AAAP01002637.1_1 - 2.9e-42 144.5 0.0 3.3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) DUF3813 PF12758.7 AAAP01002637.1_2 - 0.043 14.1 1.2 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Asp_Glu_race PF01177.22 AAAP01002638.1_1 - 2.3e-19 70.1 0.0 2.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF1919 PF08942.10 AAAP01002638.1_1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) LysR_substrate PF03466.20 AAAP01002639.1_1 - 3.6e-36 124.5 4.1 4e-36 124.3 4.1 1.0 1 0 0 1 1 1 1 LysR substrate binding domain AMP-binding PF00501.28 AAAP01002640.1_1 - 8.4e-80 268.4 0.0 1.1e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01002640.1_1 - 2.1e-24 86.3 0.9 4.1e-24 85.3 0.9 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TsaE PF02367.17 AAAP01002642.1_1 - 1.5e-30 105.7 0.0 2.2e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE APH PF01636.23 AAAP01002642.1_1 - 4e-08 33.5 0.6 1e-07 32.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC_tran PF00005.27 AAAP01002642.1_1 - 0.0013 19.3 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 AAAP01002642.1_1 - 0.0099 15.6 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AAAP01002642.1_1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01002642.1_1 - 0.04 14.3 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AAAP01002642.1_1 - 0.055 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AAAP01002642.1_1 - 0.068 12.7 0.2 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01002642.1_1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01002642.1_1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 AAAP01002642.1_1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 AAAP01002642.1_1 - 0.25 11.4 0.0 0.43 10.6 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain HATPase_c PF02518.26 AAAP01002642.1_2 - 6.7e-27 94.2 0.0 8.3e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01002642.1_2 - 0.0012 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAAP01002642.1_2 - 0.0016 18.3 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01002642.1_2 - 0.074 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arm-DNA-bind_3 PF13356.6 AAAP01002643.1_1 - 3.2 8.2 6.5 10 6.6 6.6 2.0 1 1 1 2 2 2 0 Arm DNA-binding domain Response_reg PF00072.24 AAAP01002643.1_2 - 1.2e-16 60.8 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01002643.1_2 - 4.7e-15 56.1 0.1 7.3e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 AAAP01002643.1_2 - 0.0051 17.2 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Peptidase_S49 PF01343.18 AAAP01002644.1_2 - 2e-29 102.6 0.0 2.7e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 AAAP01002644.1_2 - 6.3e-07 28.7 0.5 9.1e-07 28.2 0.5 1.1 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 AAAP01002644.1_2 - 0.0016 18.3 0.0 0.051 13.4 0.0 2.1 2 0 0 2 2 2 1 Clp protease ECH_1 PF00378.20 AAAP01002644.1_2 - 0.12 11.7 0.0 0.43 9.8 0.3 1.8 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 AAAP01002645.1_1 - 2.4e-95 319.7 0.0 2.9e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme FecCD PF01032.18 AAAP01002646.1_1 - 3.1e-95 318.8 31.8 3.9e-95 318.5 31.8 1.0 1 0 0 1 1 1 1 FecCD transport family PolyA_pol PF01743.20 AAAP01002647.1_1 - 3e-24 85.8 0.4 4.5e-24 85.3 0.4 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AAAP01002647.1_1 - 4.6e-08 32.7 0.4 9.3e-08 31.7 0.0 1.6 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Phage_holin_3_6 PF07332.11 AAAP01002647.1_2 - 0.013 15.5 0.5 0.017 15.2 0.5 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 AAAP01002647.1_2 - 0.026 14.2 0.8 0.028 14.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NUDIX PF00293.28 AAAP01002647.1_3 - 1.3e-15 57.6 0.0 1.6e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Caroten_synth PF04240.12 AAAP01002647.1_3 - 0.11 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Carotenoid biosynthesis protein Response_reg PF00072.24 AAAP01002648.1_1 - 7.4e-23 80.9 0.1 9e-23 80.6 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AAAP01002648.1_2 - 1.4e-18 67.1 0.1 2.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain CheB_methylest PF01339.17 AAAP01002648.1_2 - 9.1e-10 38.5 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 CheB methylesterase BPD_transp_1 PF00528.22 AAAP01002649.1_2 - 3.8e-20 72.4 20.1 3.8e-20 72.4 20.1 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PIG-U PF06728.13 AAAP01002649.1_2 - 0.084 11.9 5.0 0.059 12.4 3.5 1.5 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U HlyD_D23 PF16576.5 AAAP01002650.1_1 - 1.7e-09 37.2 0.0 3.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01002650.1_1 - 2.2e-07 31.5 0.7 1.3e-05 25.8 0.1 2.8 2 1 0 2 2 2 1 HlyD family secretion protein TPR_MLP1_2 PF07926.12 AAAP01002650.1_1 - 0.021 14.9 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4926 PF16277.5 AAAP01002650.1_1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) ACR_tran PF00873.19 AAAP01002650.1_2 - 3.9e-63 213.6 0.0 5.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF900 PF05990.12 AAAP01002651.1_1 - 7.1e-67 225.3 0.0 1e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 AAAP01002651.1_1 - 4.7e-05 24.1 3.3 4.7e-05 24.1 3.3 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AAAP01002651.1_1 - 0.0061 16.4 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase LCAT PF02450.15 AAAP01002651.1_1 - 0.0086 15.3 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 AAAP01002651.1_1 - 0.12 11.6 0.0 0.47 9.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 AAAP01002651.1_1 - 0.29 10.7 0.0 0.42 10.1 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Cupredoxin_1 PF13473.6 AAAP01002652.1_2 - 0.0011 19.0 0.0 0.0038 17.3 0.0 1.8 1 1 0 1 1 1 1 Cupredoxin-like domain DUF1039 PF06287.11 AAAP01002652.1_3 - 0.021 15.2 0.1 0.029 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) HTH_23 PF13384.6 AAAP01002653.1_3 - 2.7e-06 27.0 2.5 0.0011 18.8 0.2 2.1 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AAAP01002653.1_3 - 0.00013 21.6 0.3 0.44 10.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_28 PF13518.6 AAAP01002653.1_3 - 0.00015 21.8 7.2 0.04 14.0 0.6 2.9 1 1 2 3 3 3 2 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01002653.1_3 - 0.00041 19.7 0.4 0.085 12.3 0.2 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 AAAP01002653.1_3 - 0.0029 17.4 0.4 0.026 14.3 0.5 2.1 2 1 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GerE PF00196.19 AAAP01002653.1_3 - 0.0047 16.5 0.0 2.2 7.9 0.0 2.6 1 1 2 3 3 3 1 Bacterial regulatory proteins, luxR family HTH_AsnC-type PF13404.6 AAAP01002653.1_3 - 0.0094 15.8 0.9 0.44 10.4 0.1 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 AAAP01002653.1_3 - 0.012 15.4 0.2 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 AAAP01002653.1_3 - 0.016 15.0 0.1 0.23 11.2 0.2 2.3 1 1 1 2 2 2 0 helix-turn-helix, Psq domain HTH_12 PF08461.10 AAAP01002653.1_3 - 0.023 14.6 0.7 0.057 13.4 0.3 1.8 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain GcrA PF07750.11 AAAP01002653.1_3 - 0.026 15.0 0.2 0.029 14.8 0.2 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_6 PF01418.17 AAAP01002653.1_3 - 0.036 14.1 0.0 6.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family CENP-B_N PF04218.13 AAAP01002653.1_3 - 0.12 12.0 0.1 2 8.1 0.0 2.5 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain PQQ PF01011.21 AAAP01002654.1_1 - 1.7e-13 49.8 0.2 6.2e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 AAAP01002654.1_1 - 2.1e-08 34.1 0.2 2e-06 27.6 0.1 1.8 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 AAAP01002654.1_1 - 0.00033 21.1 5.3 0.49 10.9 0.1 3.3 3 1 0 3 3 3 2 PQQ-like domain DUF5133 PF17196.4 AAAP01002654.1_2 - 0.014 15.6 0.3 0.014 15.6 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF5133) EAL PF00563.20 AAAP01002655.1_2 - 4e-19 69.1 0.0 4.8e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain LysR_substrate PF03466.20 AAAP01002656.1_1 - 1.2e-33 116.3 1.4 1.4e-33 116.0 1.4 1.0 1 0 0 1 1 1 1 LysR substrate binding domain VitK2_biosynth PF02621.14 AAAP01002656.1_1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis DUF2274 PF10038.9 AAAP01002656.1_2 - 6.8e-32 109.7 0.0 7.5e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2274) TrbI PF03743.14 AAAP01002656.1_3 - 1.4e-58 197.8 0.5 1.6e-58 197.7 0.5 1.0 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein ABC_tran PF00005.27 AAAP01002657.1_1 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002657.1_1 - 0.00018 21.4 0.1 0.00022 21.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01002657.1_1 - 0.00025 21.6 0.0 0.00026 21.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01002657.1_1 - 0.00036 20.2 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AAAP01002657.1_1 - 0.00082 18.8 0.0 0.00085 18.8 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AAAP01002657.1_1 - 0.0017 18.1 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAAP01002657.1_1 - 0.0059 16.2 0.0 0.0063 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01002657.1_1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 AAAP01002657.1_1 - 0.018 14.5 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 AAAP01002657.1_1 - 0.022 14.8 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 AAAP01002657.1_1 - 0.022 13.9 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.6 AAAP01002657.1_1 - 0.031 14.0 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAAP01002657.1_1 - 0.032 13.8 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01002657.1_1 - 0.1 13.0 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 AAAP01002657.1_1 - 0.1 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 AAAP01002657.1_1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01002657.1_1 - 0.14 11.7 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AAAP01002657.1_1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 AAAP01002657.1_1 - 0.24 10.0 0.1 0.26 9.9 0.1 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AAAP01002657.1_1 - 0.34 8.4 0.1 0.33 8.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cupredoxin_1 PF13473.6 AAAP01002657.1_3 - 0.0028 17.7 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 2 Cupredoxin-like domain Cu-oxidase PF00394.22 AAAP01002657.1_3 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Multicopper oxidase Lactonase PF10282.9 AAAP01002657.1_4 - 1.2e-14 54.3 0.3 3.1e-06 26.7 0.1 3.6 1 1 2 3 3 3 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AAAP01002657.1_4 - 1.1e-12 47.2 2.5 3.9e-05 22.4 0.0 4.1 1 1 1 4 4 4 3 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 AAAP01002657.1_4 - 1.3e-10 41.4 0.2 1.3 9.3 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF4221 PF13970.6 AAAP01002657.1_4 - 1.6e-06 28.0 0.0 0.59 9.6 0.0 4.0 1 1 3 4 4 4 2 Domain of unknown function (DUF4221) NHL PF01436.21 AAAP01002657.1_4 - 2.5e-05 24.1 0.6 9.9 6.4 0.0 6.5 7 1 1 8 8 8 1 NHL repeat SGL PF08450.12 AAAP01002657.1_4 - 3.4e-05 23.5 1.2 1.4 8.4 0.0 3.8 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region nos_propeller_2 PF18793.1 AAAP01002657.1_4 - 0.11 12.9 0.3 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat 2 FlaG PF03646.15 AAAP01002657.1_4 - 1.5 9.1 13.0 37 4.6 0.1 5.5 6 0 0 6 6 6 0 FlaG protein cobW PF02492.19 AAAP01002658.1_1 - 7.3e-58 195.0 0.1 9.4e-58 194.7 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAAP01002658.1_1 - 4.1e-23 81.1 0.0 7e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 AAAP01002658.1_1 - 4.1e-05 23.6 0.1 0.06 13.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 AAAP01002658.1_1 - 0.0069 16.8 0.2 0.016 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 AAAP01002658.1_1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 AAAP01002658.1_1 - 0.046 13.8 0.1 0.13 12.3 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 AAAP01002658.1_1 - 0.052 12.5 2.0 1.9 7.4 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AAAP01002658.1_1 - 0.063 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AAAP01002658.1_1 - 0.071 13.7 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01002658.1_1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAAP01002658.1_1 - 0.08 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 AAAP01002658.1_1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01002658.1_1 - 0.091 13.3 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01002658.1_1 - 0.097 12.3 0.4 11 5.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 AAAP01002658.1_1 - 0.1 12.1 0.1 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 AAAP01002658.1_1 - 0.11 12.7 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01002658.1_1 - 0.16 11.7 0.3 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAAP01002658.1_1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF4096 PF13340.6 AAAP01002659.1_2 - 1.3e-19 70.1 4.7 2.2e-19 69.4 4.7 1.3 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) FliT PF05400.13 AAAP01002659.1_2 - 0.062 14.1 0.3 0.18 12.6 0.1 1.9 2 0 0 2 2 2 0 Flagellar protein FliT Transposase_20 PF02371.16 AAAP01002659.1_3 - 8.6e-14 51.6 0.1 1.8e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family Patatin PF01734.22 AAAP01002660.1_1 - 5.4e-11 43.1 11.4 2.5e-10 40.9 11.4 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Malectin PF11721.8 AAAP01002661.1_1 - 5.7e-46 156.6 0.0 1.8e-26 93.2 0.0 3.3 3 0 0 3 3 3 3 Malectin domain Malectin_like PF12819.7 AAAP01002661.1_1 - 0.0011 18.2 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Malectin-like domain Molybdopterin_N PF18364.1 AAAP01002661.1_1 - 0.03 14.3 0.1 0.57 10.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain AP4E_app_platf PF14807.6 AAAP01002661.1_1 - 0.069 13.5 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform BPD_transp_1 PF00528.22 AAAP01002662.1_1 - 2.1e-22 79.8 20.5 2.1e-22 79.8 20.5 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MalF_P2 PF14785.6 AAAP01002662.1_1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain DUF3267 PF11667.8 AAAP01002662.1_1 - 6.4 7.1 12.9 1.6 9.1 0.2 3.1 4 0 0 4 4 4 0 Putative zincin peptidase BPD_transp_1 PF00528.22 AAAP01002662.1_2 - 1.4e-16 60.8 22.0 1.4e-16 60.8 22.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1077 PF06417.12 AAAP01002662.1_2 - 0.064 13.3 1.0 0.18 11.8 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) Mur_ligase_M PF08245.12 AAAP01002663.1_1 - 2.7e-35 122.1 0.0 3.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AAAP01002663.1_1 - 1.1e-09 38.4 0.2 3.1e-09 37.0 0.2 1.8 1 1 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AAAP01002663.1_2 - 2.8e-25 88.4 0.0 5.1e-24 84.4 0.0 2.2 1 1 1 2 2 2 1 Mur ligase family, glutamate ligase domain RraA-like PF03737.15 AAAP01002663.1_2 - 0.038 14.1 0.2 0.34 11.1 0.1 2.0 1 1 0 2 2 2 0 Aldolase/RraA PAS_9 PF13426.7 AAAP01002664.1_1 - 2.2e-22 79.3 0.0 2.3e-09 37.4 0.0 3.2 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AAAP01002664.1_1 - 4.1e-14 52.5 0.1 3.9e-05 23.6 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AAAP01002664.1_1 - 1.1e-13 51.4 0.2 0.0067 16.7 0.0 3.1 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 AAAP01002664.1_1 - 1.9e-12 47.3 2.5 2.9e-06 27.5 0.1 4.0 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AAAP01002664.1_1 - 5.6e-12 45.4 0.1 0.00011 22.1 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.7 AAAP01002664.1_1 - 4.9e-05 23.5 0.0 0.1 12.7 0.0 3.3 3 1 1 4 4 4 2 PAS fold LTXXQ PF07813.12 AAAP01002664.1_1 - 0.067 13.9 0.4 0.16 12.7 0.4 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein DUF1329 PF07044.11 AAAP01002664.1_1 - 0.071 12.4 0.7 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1329) CFIA_Pcf11 PF11526.8 AAAP01002664.1_1 - 0.13 12.8 5.3 0.46 11.0 0.8 2.5 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 PBP_dimer PF03717.15 AAAP01002665.1_1 - 6e-13 49.5 0.0 8.2e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Transpeptidase PF00905.22 AAAP01002665.1_1 - 0.0017 17.7 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain DUF5518 PF17647.1 AAAP01002666.1_1 - 0.053 13.7 11.5 0.059 13.5 11.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Metallophos PF00149.28 AAAP01002666.1_2 - 5.5e-12 46.6 0.0 9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01002666.1_2 - 1.1e-09 38.6 0.0 4.5e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Flp_Fap PF04964.14 AAAP01002667.1_1 - 3.2e-14 52.5 4.5 3.2e-14 52.5 4.5 1.7 1 1 1 2 2 2 2 Flp/Fap pilin component Flp1_like PF16982.5 AAAP01002667.1_1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain PsbN PF02468.15 AAAP01002667.1_1 - 0.084 12.7 1.1 0.12 12.2 1.1 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Ribosomal_TL5_C PF14693.6 AAAP01002667.1_3 - 2.4e-24 85.5 0.2 4.7e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AAAP01002667.1_3 - 4.8e-23 81.5 0.0 1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L25p family Pept_tRNA_hydro PF01195.19 AAAP01002667.1_4 - 5.2e-12 46.0 0.0 5.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase CinA PF02464.17 AAAP01002668.1_1 - 0.089 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Competence-damaged protein K_trans PF02705.16 AAAP01002668.1_2 - 3.3e-118 395.5 0.3 3.8e-118 395.3 0.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter SLATT_fungal PF18142.1 AAAP01002668.1_2 - 0.23 11.5 1.0 0.59 10.1 1.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Rhodanese PF00581.20 AAAP01002669.1_1 - 2.9e-06 27.8 0.0 4.7e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Glyoxalase PF00903.25 AAAP01002670.1_1 - 1.1e-13 51.5 1.2 1.6e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAAP01002670.1_1 - 0.00086 19.5 0.2 0.56 10.5 0.5 3.5 2 2 1 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAAP01002670.1_1 - 0.63 10.1 4.5 70 3.5 4.4 2.4 1 1 0 1 1 1 0 Glyoxalase-like domain RibD_C PF01872.17 AAAP01002671.1_1 - 1.5e-22 80.4 0.1 2e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 AAAP01002671.1_1 - 0.0031 17.2 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase Glyco_hydro_43 PF04616.14 AAAP01002671.1_2 - 5.7e-06 25.8 0.2 1e-05 25.0 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 TAT_signal PF10518.9 AAAP01002671.1_2 - 1.4 8.9 10.0 1 9.3 8.3 1.7 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence HlyD_3 PF13437.6 AAAP01002672.1_1 - 2.5e-16 60.3 5.2 4e-16 59.6 0.3 3.0 3 0 0 3 3 3 1 HlyD family secretion protein HlyD PF00529.20 AAAP01002672.1_1 - 2.7e-12 46.4 1.2 5.8e-12 45.3 1.0 2.0 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_D23 PF16576.5 AAAP01002672.1_1 - 1.9e-09 37.1 2.0 4.2e-09 35.9 2.0 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion PspA_IM30 PF04012.12 AAAP01002672.1_1 - 0.01 15.4 9.5 0.011 15.3 3.8 2.3 2 0 0 2 2 2 0 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 AAAP01002672.1_1 - 0.06 13.6 8.7 0.43 10.8 7.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 PilJ PF13675.6 AAAP01002672.1_1 - 0.13 12.3 4.1 0.12 12.4 0.6 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FUSC PF04632.12 AAAP01002672.1_1 - 0.16 10.5 5.7 0.22 10.0 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 AAAP01002672.1_1 - 0.17 11.9 9.9 4.5 7.3 4.0 2.9 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMCO5 PF14992.6 AAAP01002672.1_1 - 0.22 11.1 6.6 0.87 9.1 6.7 1.7 1 1 1 2 2 2 0 TMCO5 family DUF4407 PF14362.6 AAAP01002672.1_1 - 0.86 8.9 7.7 1.3 8.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 AAAP01002672.1_1 - 3.8 6.5 5.4 14 4.6 5.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 AAAP01002672.1_1 - 9.2 6.1 10.8 11 5.8 2.0 3.2 2 1 1 3 3 3 0 Septum formation initiator Oxidored_q4 PF00507.19 AAAP01002672.1_2 - 6.4e-21 74.4 5.1 6.4e-21 74.4 5.1 1.4 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 NADHdh PF00146.21 AAAP01002672.1_3 - 5.8e-09 35.7 0.6 5.8e-09 35.7 0.6 1.7 1 1 1 2 2 2 1 NADH dehydrogenase MgsA_C PF12002.8 AAAP01002673.1_1 - 2e-57 193.8 0.0 2.2e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal DUF2560 PF10834.8 AAAP01002673.1_1 - 0.17 12.1 0.2 0.27 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) Peptidase_M32 PF02074.15 AAAP01002673.1_2 - 4.9e-47 160.8 0.0 5.8e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF3234 PF11572.8 AAAP01002673.1_2 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3234) Asparaginase PF00710.20 AAAP01002674.1_2 - 1.8e-36 125.5 0.2 3.6e-36 124.5 0.2 1.6 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AAAP01002674.1_2 - 3.2e-15 56.3 7.3 8.3e-15 55.0 0.2 3.9 5 0 0 5 5 5 1 Glutaminase/Asparaginase C-terminal domain Abhydrolase_6 PF12697.7 AAAP01002675.1_1 - 1.1e-20 75.2 4.3 1.5e-20 74.8 4.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01002675.1_1 - 1.5e-18 67.4 0.0 2.4e-16 60.1 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01002675.1_1 - 1.8e-13 50.3 0.1 5.6e-13 48.7 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AAAP01002675.1_1 - 6e-06 25.9 0.0 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 AAAP01002675.1_1 - 0.00087 19.2 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase DLH PF01738.18 AAAP01002675.1_1 - 0.036 13.6 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family UPF0227 PF05728.12 AAAP01002675.1_1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 AAAP01002675.1_1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 AAAP01002675.1_1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_2 PF01674.18 AAAP01002675.1_1 - 0.29 10.6 0.1 1.7 8.1 0.1 2.0 1 1 0 1 1 1 0 Lipase (class 2) Glyoxalase PF00903.25 AAAP01002675.1_2 - 0.067 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01002675.1_2 - 0.13 13.0 0.1 0.27 12.0 0.1 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain GST_N_3 PF13417.6 AAAP01002675.1_3 - 8.9e-18 64.5 0.1 1.5e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01002675.1_3 - 2.7e-13 50.1 0.0 5.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01002675.1_3 - 2.4e-12 47.0 0.0 4.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAAP01002675.1_3 - 4.6e-11 42.8 0.0 7.3e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAAP01002675.1_3 - 3.9e-10 39.6 0.6 7e-10 38.8 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAAP01002675.1_3 - 3.5e-07 30.4 0.0 7.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAAP01002675.1_3 - 0.015 16.0 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain FKBP_C PF00254.28 AAAP01002676.1_1 - 1.9e-15 56.9 0.0 2.1e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PfkB PF00294.24 AAAP01002676.1_2 - 3.3e-40 138.3 0.0 4.3e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF5518 PF17647.1 AAAP01002676.1_2 - 0.05 13.7 0.8 0.085 13.0 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) MFS_1 PF07690.16 AAAP01002677.1_2 - 0.0056 15.6 10.5 0.0068 15.4 10.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 AAAP01002677.1_2 - 0.088 11.2 5.5 0.55 8.6 5.9 1.8 1 1 1 2 2 2 0 Transmembrane secretion effector DUF1772 PF08592.11 AAAP01002677.1_2 - 0.71 10.2 6.7 0.17 12.2 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF456 PF04306.13 AAAP01002677.1_3 - 1.9e-05 25.0 5.6 2.6e-05 24.5 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 AAAP01002677.1_3 - 0.00024 20.8 17.8 0.00024 20.8 17.8 2.6 3 0 0 3 3 3 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 AAAP01002677.1_3 - 0.003 17.3 16.1 0.003 17.3 16.1 2.7 3 0 0 3 3 3 1 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 AAAP01002677.1_3 - 0.006 16.4 6.4 0.006 16.4 6.4 2.6 2 1 2 4 4 4 2 Glycine zipper 2TM domain MccV PF17508.2 AAAP01002677.1_3 - 0.0062 17.1 3.0 0.0091 16.5 3.0 1.3 1 0 0 1 1 1 1 Microcin V bacteriocin Gly-zipper_Omp PF13488.6 AAAP01002677.1_3 - 0.03 14.3 6.6 0.03 14.3 6.6 2.9 2 1 2 4 4 4 0 Glycine zipper Tim17 PF02466.19 AAAP01002677.1_3 - 2.1 8.7 9.2 3.2 8.2 8.3 1.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_2_4 PF16082.5 AAAP01002677.1_3 - 3.6 7.4 9.2 2.3 8.0 7.5 1.6 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF726 PF05277.12 AAAP01002677.1_3 - 7.1 5.5 5.5 7.6 5.4 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RTX PF02382.15 AAAP01002677.1_3 - 9.1 5.9 8.0 11 5.5 8.0 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein BcrAD_BadFG PF01869.20 AAAP01002678.1_1 - 1.8e-14 53.9 0.1 2.2e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Response_reg PF00072.24 AAAP01002678.1_3 - 1.1e-22 80.3 0.0 1.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01002678.1_3 - 1.7e-18 65.9 0.2 2.6e-18 65.3 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01002678.1_3 - 6.1e-07 29.0 0.5 2e-06 27.4 0.5 2.0 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01002678.1_3 - 0.00022 20.6 0.1 0.00056 19.4 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01002678.1_3 - 0.00053 19.7 0.4 0.0025 17.6 0.2 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 AAAP01002678.1_3 - 0.001 18.6 0.1 0.0028 17.2 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AAAP01002678.1_3 - 0.0091 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01002678.1_3 - 0.012 15.7 2.5 0.092 12.9 0.1 3.2 2 2 1 3 3 3 0 Helix-turn-helix domain RepB PF07506.11 AAAP01002678.1_3 - 0.012 15.7 0.1 0.047 13.8 0.1 1.9 3 0 0 3 3 3 0 RepB plasmid partitioning protein HTH_20 PF12840.7 AAAP01002678.1_3 - 0.013 15.5 0.3 0.042 13.9 0.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 AAAP01002678.1_3 - 0.13 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 ECF sigma factor ETF_QO PF05187.13 AAAP01002679.1_1 - 2.3e-50 169.0 0.2 3.1e-50 168.7 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 AAAP01002679.1_1 - 0.011 16.3 1.0 0.02 15.5 1.0 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01002679.1_1 - 0.096 12.8 0.9 0.26 11.5 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Peptidase_S58 PF03576.14 AAAP01002679.1_2 - 1.8e-20 73.6 3.0 2.2e-20 73.4 3.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 MscL PF01741.18 AAAP01002680.1_1 - 0.033 14.5 0.4 0.064 13.6 0.4 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF975 PF06161.11 AAAP01002680.1_1 - 0.079 12.7 11.8 0.015 15.1 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF975) DUF3169 PF11368.8 AAAP01002680.1_1 - 0.18 11.3 3.8 0.14 11.6 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) MotA_ExbB PF01618.16 AAAP01002680.1_1 - 2.4 7.9 4.7 0.68 9.7 1.8 1.7 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF3097 PF11296.8 AAAP01002680.1_2 - 5.9e-123 409.4 0.7 6.7e-123 409.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) Transposase_20 PF02371.16 AAAP01002681.1_1 - 2.5e-26 91.8 0.1 5.1e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAAP01002681.1_1 - 1.1e-08 35.1 0.1 3.2e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Transposase DASH_Hsk3 PF08227.11 AAAP01002681.1_1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like MCD PF05292.11 AAAP01002681.1_1 - 0.088 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain HHH_2 PF12826.7 AAAP01002681.1_1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 AAAP01002681.1_1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif MORN_2 PF07661.13 AAAP01002681.1_3 - 0.38 11.1 2.0 58 4.4 0.6 3.3 3 1 0 3 3 3 0 MORN repeat variant DUF5131 PF07505.11 AAAP01002682.1_1 - 1.3e-46 159.1 0.1 1.6e-46 158.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) DUF2407_C PF13373.6 AAAP01002682.1_2 - 0.079 13.1 0.0 0.096 12.9 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain NAD_synthase PF02540.17 AAAP01002682.1_4 - 0.098 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 NAD synthase DUF228 PF02989.14 AAAP01002683.1_3 - 0.1 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Glyco_hydro_3 PF00933.21 AAAP01002684.1_1 - 1.9e-57 195.1 0.0 3.2e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 AAAP01002684.1_1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain TetR_N PF00440.23 AAAP01002684.1_2 - 9.4e-05 22.1 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TonB_dep_Rec PF00593.24 AAAP01002685.1_1 - 1.5e-18 68.0 1.5 1.8e-18 67.7 1.5 1.0 1 0 0 1 1 1 1 TonB dependent receptor GIDA PF01134.22 AAAP01002686.1_1 - 6.1e-155 516.1 0.0 7.4e-155 515.9 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01002686.1_1 - 3.3e-09 36.6 5.0 3.9e-09 36.4 5.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAAP01002686.1_1 - 2e-07 30.5 1.6 6.9e-07 28.8 1.7 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01002686.1_1 - 8.5e-05 21.8 17.9 0.00081 18.6 7.0 2.6 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 AAAP01002686.1_1 - 0.00019 20.5 3.9 0.037 12.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 AAAP01002686.1_1 - 0.0006 19.2 0.5 0.022 14.0 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01002686.1_1 - 0.00082 19.1 1.1 0.00082 19.1 1.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAAP01002686.1_1 - 0.0014 19.1 1.4 0.0029 18.1 1.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01002686.1_1 - 0.0027 17.0 2.2 0.005 16.2 2.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 AAAP01002686.1_1 - 0.0033 17.4 0.2 0.0033 17.4 0.2 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 AAAP01002686.1_1 - 0.005 15.6 6.9 0.051 12.3 3.8 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 AAAP01002686.1_1 - 0.018 14.3 3.3 0.81 8.9 4.4 2.6 2 1 0 2 2 2 0 Thi4 family YAcAr PF10686.9 AAAP01002686.1_1 - 0.037 14.0 0.9 0.88 9.6 0.0 2.6 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family XdhC_C PF13478.6 AAAP01002686.1_1 - 0.064 13.8 1.5 0.83 10.2 1.8 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 AAAP01002686.1_1 - 0.087 12.0 2.6 0.095 11.9 1.6 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 AAAP01002686.1_1 - 0.35 9.9 4.8 4.8 6.1 2.6 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein LpxK PF02606.14 AAAP01002687.1_1 - 3.6e-28 98.6 0.0 4.1e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase CSTF_C PF14304.6 AAAP01002687.1_1 - 0.18 11.4 0.3 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF2093 PF09866.9 AAAP01002687.1_2 - 1.1e-24 85.5 0.0 1.5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2093) dCMP_cyt_deam_2 PF08211.12 AAAP01002687.1_3 - 9.4e-11 42.1 0.8 1e-10 42.0 0.8 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 AAAP01002687.1_3 - 1.9e-08 34.1 0.2 2.3e-08 33.8 0.2 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RrnaAD PF00398.20 AAAP01002688.1_1 - 1.6e-40 138.9 0.0 2.1e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 AAAP01002688.1_1 - 0.0027 17.5 0.0 0.0087 15.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002688.1_1 - 0.057 14.1 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 AAAP01002688.1_1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein GHMP_kinases_N PF00288.26 AAAP01002688.1_2 - 0.1 12.8 2.6 0.13 12.5 0.1 2.2 3 0 0 3 3 3 0 GHMP kinases N terminal domain DHDPS PF00701.22 AAAP01002689.1_1 - 6.4e-21 74.3 0.0 7.3e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family BtpA PF03437.15 AAAP01002689.1_1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 BtpA family T4SS-DNA_transf PF02534.14 AAAP01002689.1_2 - 0.00063 18.7 0.0 0.00072 18.5 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF3040 PF11239.8 AAAP01002689.1_2 - 0.35 11.2 4.3 3.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AA_permease_2 PF13520.6 AAAP01002690.1_1 - 3.1e-11 42.8 17.6 3.7e-11 42.5 17.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01002690.1_1 - 3.5e-08 32.5 13.4 4.2e-08 32.2 13.4 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S15 PF00312.22 AAAP01002690.1_2 - 9.1e-37 125.1 1.7 1.1e-36 124.9 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 Phage_lysozyme2 PF18013.1 AAAP01002690.1_2 - 0.16 12.0 0.1 0.22 11.5 0.1 1.3 1 1 0 1 1 1 0 Phage tail lysozyme META PF03724.16 AAAP01002691.1_1 - 8.4e-19 67.6 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 META domain NESP55 PF06390.12 AAAP01002691.1_2 - 1.9 8.0 3.4 2.1 7.9 3.4 1.0 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) PALP PF00291.25 AAAP01002691.1_3 - 1.7e-12 47.4 0.0 1.9e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_trans_1_4 PF13692.6 AAAP01002692.1_1 - 5.6e-14 52.7 0.0 1.2e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01002692.1_1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 DUF1864 PF08933.11 AAAP01002692.1_1 - 0.025 13.3 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) PEPcase PF00311.17 AAAP01002693.1_1 - 1.5e-21 76.2 0.0 8.7e-19 67.1 0.0 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase Transposon_TraM PF12508.8 AAAP01002693.1_1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Conjugative transposon, TraM DUF11 PF01345.18 AAAP01002694.1_3 - 2.3e-06 27.8 11.5 2.3e-06 27.8 11.5 2.3 2 1 0 2 2 2 1 Domain of unknown function DUF11 Glyco_transf_41 PF13844.6 AAAP01002695.1_1 - 0.0051 15.3 0.0 0.0054 15.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 41 Hexapep PF00132.24 AAAP01002695.1_2 - 1.4e-13 50.0 23.4 3.7e-05 23.3 0.3 3.6 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01002695.1_2 - 1.1e-05 25.1 1.6 0.0012 18.6 0.0 3.4 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase IalB PF06776.12 AAAP01002696.1_1 - 2.6e-35 121.4 0.0 4.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Invasion associated locus B (IalB) protein DUF2870 PF11069.8 AAAP01002696.1_1 - 0.0055 17.1 0.2 0.011 16.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DEC-1_N PF04625.13 AAAP01002696.1_1 - 1.1 8.2 10.2 0.046 12.7 4.6 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PepSY_2 PF13670.6 AAAP01002696.1_1 - 7.3 6.7 7.6 5.3 7.1 2.0 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Helicase_C PF00271.31 AAAP01002697.1_1 - 2.1e-13 50.6 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAAP01002697.1_1 - 6.9e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 AAAP01002697.1_1 - 0.016 15.2 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_30 PF13604.6 AAAP01002697.1_1 - 0.037 13.7 1.7 0.04 13.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AAAP01002697.1_1 - 0.065 13.6 0.1 0.19 12.0 0.1 1.8 2 1 0 2 2 2 0 AAA domain rve_3 PF13683.6 AAAP01002698.1_1 - 5.3e-27 93.4 0.0 1.1e-26 92.3 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 AAAP01002698.1_1 - 7.6e-19 68.1 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 AAAP01002698.1_1 - 0.00037 20.3 0.0 0.00043 20.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve_2 PF13333.6 AAAP01002698.1_1 - 0.041 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.20 AAAP01002698.1_2 - 2.9e-20 72.4 0.2 3.3e-20 72.2 0.2 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAAP01002698.1_2 - 3e-07 30.5 0.1 4.5e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01002698.1_2 - 3.6e-07 30.1 0.1 7.5e-07 29.1 0.0 1.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01002698.1_2 - 7.7e-07 28.7 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AAAP01002698.1_2 - 0.00023 21.2 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 AAAP01002698.1_2 - 0.018 14.7 0.1 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1_2 PF13022.6 AAAP01002698.1_2 - 0.024 14.8 1.2 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase Terminase_5 PF06056.12 AAAP01002698.1_2 - 0.063 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.6 AAAP01002698.1_2 - 0.12 12.9 0.0 0.17 12.5 0.0 1.3 1 1 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 AAAP01002698.1_2 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Fer2_3 PF13085.6 AAAP01002699.1_1 - 0.00053 20.0 0.0 0.00061 19.8 0.0 1.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_2 PF00890.24 AAAP01002699.1_2 - 3.6e-59 200.9 0.4 5.2e-59 200.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAAP01002699.1_2 - 2.2e-24 85.9 0.0 3.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAAP01002699.1_2 - 0.0028 16.9 0.2 0.047 12.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CusF_Ec PF11604.8 AAAP01002700.1_1 - 7e-27 93.2 0.3 1e-26 92.6 0.3 1.3 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF PCB_OB PF17092.5 AAAP01002700.1_1 - 0.0013 19.4 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain DUF305 PF03713.13 AAAP01002700.1_1 - 0.42 10.7 2.1 0.52 10.4 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF305) Cytochrome_CBB3 PF13442.6 AAAP01002700.1_2 - 1.6e-08 34.7 0.1 3.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01002700.1_2 - 2.2e-05 25.5 0.4 8e-05 23.7 0.0 2.0 3 0 0 3 3 3 1 Cytochrome c TTRAP PF14203.6 AAAP01002700.1_2 - 0.003 17.5 0.1 0.0045 17.0 0.1 1.2 1 0 0 1 1 1 1 Putative tranposon-transfer assisting protein PK PF00224.21 AAAP01002701.1_1 - 1.7e-108 362.6 0.1 2.1e-108 362.3 0.1 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAAP01002701.1_1 - 2.1e-16 60.2 0.9 2.1e-16 60.2 0.9 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 AAAP01002701.1_1 - 0.00025 20.3 2.4 0.025 13.7 0.3 3.1 2 1 1 3 3 3 2 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 AAAP01002701.1_1 - 0.003 16.6 1.0 0.026 13.5 0.0 2.5 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain DUF4253 PF14062.6 AAAP01002701.1_1 - 0.065 13.4 0.6 6.3 7.0 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4253) EAL PF00563.20 AAAP01002702.1_1 - 2.2e-63 213.9 0.0 2.5e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain HTH_23 PF13384.6 AAAP01002702.1_2 - 1.8e-07 30.8 0.2 2.6e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 AAAP01002702.1_2 - 5.2e-06 26.3 0.9 1.9e-05 24.5 0.7 1.9 1 1 0 1 1 1 1 MarR family CENP-B_N PF04218.13 AAAP01002702.1_2 - 2.3e-05 23.9 0.1 3.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 AAAP01002702.1_2 - 0.00027 20.6 1.3 0.00047 19.9 1.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 AAAP01002702.1_2 - 0.00028 20.4 0.1 0.00035 20.0 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_29 PF13551.6 AAAP01002702.1_2 - 0.00054 19.9 0.1 0.00083 19.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AAAP01002702.1_2 - 0.0011 18.6 0.2 0.0019 17.8 0.2 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AAAP01002702.1_2 - 0.0019 18.1 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.15 AAAP01002702.1_2 - 0.0023 18.0 0.3 0.0033 17.5 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_40 PF14493.6 AAAP01002702.1_2 - 0.0093 16.4 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 AAAP01002702.1_2 - 0.011 15.5 0.2 0.027 14.3 0.1 1.7 1 1 1 2 2 2 0 HTH DNA binding domain HTH_28 PF13518.6 AAAP01002702.1_2 - 0.014 15.5 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01002702.1_2 - 0.019 14.5 0.3 0.032 13.8 0.3 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAAP01002702.1_2 - 0.021 14.3 0.5 0.11 12.1 0.5 2.0 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_20 PF12840.7 AAAP01002702.1_2 - 0.038 14.0 0.2 0.059 13.4 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage-MuB_C PF09077.11 AAAP01002702.1_2 - 0.042 13.7 0.5 0.17 11.8 0.3 1.9 1 1 1 2 2 2 0 Mu B transposition protein, C terminal UPF0122 PF04297.14 AAAP01002702.1_2 - 0.091 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TrmB PF01978.19 AAAP01002702.1_2 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_S9 PF00326.21 AAAP01002703.1_1 - 9.1e-07 28.6 0.0 9.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 AAAP01002703.1_1 - 0.0016 18.0 0.1 0.0022 17.5 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 AAAP01002703.1_1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 AAAP01002703.1_1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SPOR PF05036.13 AAAP01002703.1_2 - 0.02 15.2 0.0 0.02 15.2 0.0 1.0 1 0 0 1 1 1 0 Sporulation related domain BPD_transp_1 PF00528.22 AAAP01002704.1_1 - 6.8e-19 68.3 5.8 8.3e-19 68.0 5.8 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01002704.1_2 - 1.9e-31 109.4 0.0 3.1e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01002704.1_2 - 9.8e-05 22.8 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01002704.1_2 - 0.00017 21.5 0.1 0.4 10.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01002704.1_2 - 0.00021 21.2 0.3 0.00043 20.2 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 AAAP01002704.1_2 - 0.0018 18.7 0.4 0.016 15.6 0.4 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAAP01002704.1_2 - 0.0023 17.6 0.1 0.0051 16.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01002704.1_2 - 0.0038 17.5 0.0 0.0088 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01002704.1_2 - 0.013 14.9 1.6 0.096 12.1 1.6 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAAP01002704.1_2 - 0.024 14.8 0.0 0.06 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01002704.1_2 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 AAAP01002704.1_2 - 0.072 12.8 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAAP01002704.1_2 - 0.095 13.2 0.1 0.16 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01002704.1_2 - 0.14 12.2 0.4 0.36 10.9 0.4 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pyr_redox_2 PF07992.14 AAAP01002704.1_3 - 1.1e-05 24.8 0.0 1.2e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sensor PF13796.6 AAAP01002704.1_3 - 0.085 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative sensor Thymidylate_kin PF02223.17 AAAP01002705.1_1 - 9.8e-33 113.4 0.0 1.1e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AAAP01002705.1_1 - 2.1e-05 24.8 0.1 3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.14 AAAP01002705.1_1 - 0.0093 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) AAA_22 PF13401.6 AAAP01002705.1_1 - 0.029 14.7 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01002705.1_1 - 0.043 13.5 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AAAP01002705.1_1 - 0.055 13.2 1.6 0.07 12.8 1.6 1.3 1 1 0 1 1 1 0 AAA domain MukB PF04310.12 AAAP01002705.1_1 - 0.091 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_33 PF13671.6 AAAP01002705.1_1 - 0.13 12.4 0.1 0.18 12.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 AAAP01002705.1_1 - 0.14 12.2 0.3 0.23 11.5 0.3 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain BPD_transp_1 PF00528.22 AAAP01002705.1_2 - 6.2e-17 61.9 13.8 6.2e-17 61.9 13.8 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component LysR_substrate PF03466.20 AAAP01002706.1_1 - 7.3e-09 35.3 0.6 9.2e-09 35.0 0.6 1.0 1 0 0 1 1 1 1 LysR substrate binding domain adh_short_C2 PF13561.6 AAAP01002706.1_2 - 2.6e-60 203.9 5.1 3e-60 203.7 5.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002706.1_2 - 2.3e-45 154.5 2.8 2.7e-45 154.2 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01002706.1_2 - 6.2e-19 68.6 1.1 8.6e-19 68.1 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01002706.1_2 - 2e-05 24.2 0.4 0.00011 21.7 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 AAAP01002706.1_2 - 0.0016 19.4 1.8 0.31 12.1 1.2 2.5 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator PepSY_2 PF13670.6 AAAP01002706.1_2 - 0.0088 16.0 0.2 0.023 14.7 0.2 1.7 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain LysR_substrate PF03466.20 AAAP01002706.1_3 - 7.9e-32 110.3 1.9 8.9e-32 110.1 1.9 1.0 1 0 0 1 1 1 1 LysR substrate binding domain Phage_int_SAM_1 PF02899.17 AAAP01002707.1_1 - 8.6e-22 77.2 0.0 1.1e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAAP01002707.1_1 - 0.00057 20.3 0.0 0.0011 19.4 0.0 1.5 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Ost5 PF05251.12 AAAP01002707.1_2 - 0.017 15.4 0.6 0.018 15.3 0.6 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 HAGH_C PF16123.5 AAAP01002707.1_3 - 5.8e-23 81.2 0.0 8.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AAAP01002707.1_3 - 8.9e-15 55.2 3.4 1.7e-14 54.3 3.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01002707.1_3 - 3.8e-05 23.3 0.8 8e-05 22.2 0.8 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_5 PF14597.6 AAAP01002707.1_3 - 0.06 12.8 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Phage_portal PF04860.12 AAAP01002708.1_1 - 2.7e-76 256.8 0.0 3.2e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein Peptidase_S78 PF04586.17 AAAP01002708.1_2 - 6.2e-30 104.5 0.0 7.4e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Caudovirus prohead serine protease PNP_UDP_1 PF01048.20 AAAP01002709.1_1 - 3.8e-42 144.2 0.1 4.5e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NAD_binding_10 PF13460.6 AAAP01002709.1_1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF305 PF03713.13 AAAP01002710.1_1 - 8.7e-21 74.7 1.5 1.1e-20 74.3 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 AAAP01002710.1_1 - 4.9e-05 23.6 0.4 8.4e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) ACR_tran PF00873.19 AAAP01002710.1_3 - 0.00013 19.8 1.5 0.00015 19.6 1.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family rve PF00665.26 AAAP01002712.1_1 - 2.9e-19 69.4 0.1 4.9e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01002712.1_1 - 2.3e-07 30.5 0.0 5.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAAP01002712.1_1 - 3.1e-07 30.4 7.7 3.1e-07 30.4 7.7 1.9 3 0 0 3 3 3 1 HTH-like domain DDE_3 PF13358.6 AAAP01002712.1_1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease rve_3 PF13683.6 AAAP01002712.1_2 - 7.6e-28 96.1 0.0 1.1e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AAAP01002712.1_2 - 2.3e-18 66.5 0.0 3.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01002712.1_2 - 0.0033 17.6 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAAP01002712.1_2 - 0.0061 16.8 0.0 0.0072 16.6 0.0 1.1 1 0 0 1 1 1 1 DDE domain YkuD PF03734.14 AAAP01002713.1_1 - 4.5e-19 69.3 0.0 5.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain HPP PF04982.13 AAAP01002714.1_1 - 7.3e-38 129.5 13.7 1.8e-37 128.3 13.7 1.7 1 0 0 1 1 1 1 HPP family CBS PF00571.28 AAAP01002714.1_1 - 1.1e-27 96.2 0.6 1e-13 51.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain Peptidase_S9 PF00326.21 AAAP01002714.1_2 - 0.0015 18.1 0.0 0.43 10.0 0.1 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AAAP01002714.1_2 - 0.0067 16.3 0.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 AAAP01002714.1_2 - 0.046 13.0 0.3 0.4 9.9 0.1 2.3 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 AAAP01002714.1_2 - 0.26 10.7 2.6 2.7 7.4 2.6 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 AAAP01002714.1_2 - 1.1 9.1 2.6 5.2 6.9 0.0 2.3 2 1 1 3 3 3 0 alpha/beta hydrolase fold Mg-por_mtran_C PF07109.11 AAAP01002715.1_2 - 2.3e-31 108.0 0.0 3.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 AAAP01002715.1_2 - 2.2e-15 57.1 0.0 3.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002715.1_2 - 1.6e-12 47.5 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002715.1_2 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002715.1_2 - 1.9e-10 40.8 0.0 2.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002715.1_2 - 4.2e-10 40.3 0.0 6.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAAP01002715.1_2 - 3.5e-08 33.3 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAAP01002715.1_2 - 7.7e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AAAP01002715.1_2 - 1.6e-06 27.7 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 AAAP01002715.1_2 - 0.00024 20.9 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 AAAP01002715.1_2 - 0.00037 20.0 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 AAAP01002715.1_2 - 0.0043 16.8 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.18 AAAP01002715.1_2 - 0.0049 16.2 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 AAAP01002715.1_2 - 0.018 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 AAAP01002715.1_2 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MethyltransfD12 PF02086.15 AAAP01002715.1_2 - 0.025 14.3 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.7 AAAP01002715.1_2 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 AAAP01002715.1_2 - 0.043 12.7 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AAAP01002715.1_2 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 AAAP01002715.1_2 - 0.24 11.0 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PUCC PF03209.15 AAAP01002715.1_3 - 2.8e-112 375.6 22.5 3.3e-112 375.4 22.5 1.0 1 0 0 1 1 1 1 PUCC protein MFS_1 PF07690.16 AAAP01002715.1_3 - 3.6e-10 39.3 43.3 8.8e-10 38.0 42.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 AAAP01002716.1_1 - 1e-06 28.0 22.4 4.4e-06 25.9 22.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01002716.1_1 - 0.058 12.2 4.2 0.059 12.2 2.8 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter ArsC PF03960.15 AAAP01002716.1_5 - 3.4e-18 65.4 0.0 4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AAAP01002716.1_5 - 0.00085 19.5 0.0 0.19 12.0 0.0 3.0 2 1 1 3 3 3 1 Glutaredoxin GXGXG PF01493.19 AAAP01002717.1_2 - 7e-13 48.6 7.4 1.4e-12 47.6 7.4 1.5 1 1 0 1 1 1 1 GXGXG motif GATase_7 PF13537.6 AAAP01002717.1_3 - 1.1e-19 70.6 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01002717.1_3 - 1.5e-17 64.0 0.0 1.9e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain CPSase_sm_chain PF00988.22 AAAP01002718.1_1 - 8.4e-49 164.7 0.0 1.2e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AAAP01002718.1_1 - 3.5e-47 160.6 0.0 4.9e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01002718.1_1 - 9.8e-09 35.3 1.1 1.7e-07 31.2 1.1 2.6 1 1 0 1 1 1 1 Peptidase C26 TusA PF01206.17 AAAP01002718.1_1 - 0.2 11.5 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA Phage_holin_3_6 PF07332.11 AAAP01002718.1_2 - 0.0048 16.9 2.2 0.0048 16.9 2.2 1.8 1 1 1 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2065 PF09838.9 AAAP01002718.1_2 - 0.014 15.4 0.2 0.033 14.2 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) SspB PF04386.13 AAAP01002719.1_1 - 0.12 12.2 0.5 0.15 11.9 0.5 1.1 1 0 0 1 1 1 0 Stringent starvation protein B p450 PF00067.22 AAAP01002719.1_2 - 9.1e-52 176.3 0.0 1.1e-51 176.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 AAAP01002719.1_3 - 4.3e-06 25.7 0.0 4.9e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FUSC PF04632.12 AAAP01002720.1_1 - 1.1e-44 153.2 25.7 1.3e-44 152.8 25.7 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family 7TM_GPCR_Srt PF10321.9 AAAP01002720.1_1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF1656 PF07869.12 AAAP01002720.1_2 - 1.6e-16 60.1 6.4 1.9e-16 59.8 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) Biotin_lipoyl_2 PF13533.6 AAAP01002720.1_3 - 2.6e-17 62.4 2.2 2.9e-17 62.2 0.4 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAAP01002720.1_3 - 0.01 15.1 1.9 0.017 14.4 1.8 1.4 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01002720.1_3 - 0.045 14.5 1.2 0.14 12.9 1.0 1.9 1 1 0 1 1 1 0 HlyD family secretion protein PBP_N PF17093.5 AAAP01002720.1_3 - 0.045 14.0 1.0 0.084 13.1 1.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Biotin_lipoyl PF00364.22 AAAP01002720.1_3 - 0.058 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme RskA PF10099.9 AAAP01002720.1_3 - 2 8.7 15.0 3.9 7.7 14.9 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Bac_DNA_binding PF00216.21 AAAP01002721.1_1 - 2.7e-27 94.8 0.1 3e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01002721.1_1 - 0.0034 17.5 0.1 0.0042 17.2 0.1 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-DNA_bdg PF14848.6 AAAP01002721.1_1 - 0.0092 16.0 0.1 0.029 14.4 0.0 1.7 2 0 0 2 2 2 1 DNA-binding domain HU-CCDC81_euk_2 PF18289.1 AAAP01002721.1_1 - 0.037 14.2 0.1 0.071 13.3 0.1 1.4 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 AAAP01002721.1_1 - 0.042 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 AP2 PF00847.20 AAAP01002721.1_2 - 0.028 14.7 0.2 0.046 13.9 0.2 1.3 1 0 0 1 1 1 0 AP2 domain Ribosomal_L32p PF01783.23 AAAP01002721.1_3 - 6.2e-13 48.8 0.4 7.4e-13 48.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family MannoseP_isomer PF01050.18 AAAP01002722.1_1 - 7.7e-65 217.4 0.7 1.1e-64 216.9 0.7 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAAP01002722.1_1 - 3.6e-16 59.5 0.0 6.7e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Cupin_2 PF07883.11 AAAP01002722.1_1 - 5.1e-09 35.7 1.4 8.3e-09 35.0 0.2 1.9 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 AAAP01002722.1_1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Mtf2_C PF14061.6 AAAP01002722.1_1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DAO_C PF16901.5 AAAP01002722.1_2 - 1.9e-13 50.4 0.1 2.2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase UPRTase PF14681.6 AAAP01002723.1_1 - 1.7e-70 236.7 0.0 2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 AAAP01002723.1_1 - 2.2e-11 43.6 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ADH_zinc_N PF00107.26 AAAP01002723.1_2 - 2.1e-30 105.3 1.5 3.8e-30 104.5 1.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01002723.1_2 - 2.5e-13 51.3 0.1 4.5e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01002723.1_2 - 1.4e-10 41.0 0.2 1.8e-09 37.4 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 AAAP01002723.1_2 - 0.003 17.4 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 AAAP01002723.1_2 - 0.0083 15.6 0.4 0.016 14.7 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase YAcAr PF10686.9 AAAP01002723.1_2 - 0.017 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family EIIA-man PF03610.16 AAAP01002723.1_2 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 PTS system fructose IIA component DOT1 PF08123.13 AAAP01002723.1_2 - 0.22 11.0 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Plug PF07715.15 AAAP01002724.1_1 - 1.6e-08 35.1 0.3 1.6e-08 35.1 0.3 1.8 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain RIP PF00161.19 AAAP01002724.1_1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosome inactivating protein MFS_1 PF07690.16 AAAP01002725.1_1 - 3.4e-17 62.4 48.1 6.9e-11 41.7 27.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily IncE PF17627.2 AAAP01002725.1_1 - 8.9 6.3 8.8 22 5.1 0.9 2.9 2 0 0 2 2 2 0 Inclusion membrane protein E Acetyltransf_CG PF14542.6 AAAP01002725.1_2 - 2.6e-26 91.5 0.0 3.1e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 AAAP01002725.1_2 - 4.8e-05 23.6 0.0 5.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AAAP01002725.1_2 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAAP01002725.1_2 - 0.0026 17.9 0.1 0.0034 17.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01002725.1_2 - 0.0065 16.4 0.0 0.0078 16.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01002725.1_2 - 0.0097 16.3 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01002725.1_2 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Cation_efflux PF01545.21 AAAP01002726.1_1 - 2.6e-05 24.0 0.1 2.8e-05 23.9 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family Metallophos PF00149.28 AAAP01002726.1_2 - 1.1e-08 35.8 0.0 5.7e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01002726.1_2 - 1.5e-07 31.7 0.0 1.5e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DAHP_snth_FXD PF18152.1 AAAP01002726.1_2 - 0.067 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain SIS PF01380.22 AAAP01002726.1_2 - 0.23 11.3 0.0 0.5 10.2 0.0 1.5 1 0 0 1 1 1 0 SIS domain Glyco_trans_4_4 PF13579.6 AAAP01002726.1_2 - 0.31 11.5 20.7 5.1 7.5 0.2 2.4 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain ATP-synt_ab PF00006.25 AAAP01002727.1_1 - 4.1e-10 39.7 0.0 5.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mor PF08765.11 AAAP01002727.1_1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Mor transcription activator family TcdB_toxin_midN PF12256.8 AAAP01002727.1_1 - 0.14 11.5 0.0 0.73 9.2 0.0 1.9 1 1 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region TPP_enzyme_N PF02776.18 AAAP01002727.1_2 - 4.2e-44 150.2 0.7 5.3e-44 149.9 0.3 1.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAAP01002727.1_2 - 1.4e-08 34.6 0.0 3.6e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AAAP01002727.1_2 - 0.00031 20.6 0.2 0.00052 19.8 0.2 1.4 1 1 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GcpE PF04551.14 AAAP01002728.1_1 - 5.8e-45 153.9 0.0 6.6e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 GcpE protein SEA PF01390.20 AAAP01002728.1_1 - 0.22 11.6 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 SEA domain K_trans PF02705.16 AAAP01002728.1_2 - 3.1e-29 101.9 1.0 3.7e-29 101.7 1.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter CHD5 PF04420.14 AAAP01002728.1_2 - 0.2 11.5 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 CHD5-like protein GATase_5 PF13507.6 AAAP01002729.1_2 - 2.6e-33 115.3 0.0 5.3e-33 114.2 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 AAAP01002729.1_2 - 1.7e-08 34.3 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AAAP01002729.1_2 - 1e-06 28.7 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 AAAP01002729.1_2 - 2.7e-06 27.3 0.0 4.1e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01002729.1_2 - 0.0007 19.4 0.2 0.0027 17.5 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AAAP01002729.1_2 - 0.0053 16.6 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family FlgD_ig PF13860.6 AAAP01002729.1_2 - 0.033 14.0 0.1 0.25 11.2 0.0 2.2 1 1 1 2 2 2 0 FlgD Ig-like domain PurS PF02700.14 AAAP01002729.1_3 - 9.5e-24 83.4 0.0 1.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase Phage_lysozyme PF00959.19 AAAP01002730.1_2 - 3.4e-13 50.0 0.0 4.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme MCPsignal PF00015.21 AAAP01002731.1_1 - 9.1e-21 74.4 12.8 1.8e-20 73.5 11.8 1.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain SBP_bac_3 PF00497.20 AAAP01002731.1_1 - 8.2e-11 41.8 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Baculo_PEP_C PF04513.12 AAAP01002731.1_1 - 0.0088 16.1 0.2 0.19 11.8 0.0 2.3 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 AAAP01002731.1_1 - 1.5 8.6 6.6 6.6 6.6 6.5 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HlyD_D23 PF16576.5 AAAP01002731.1_2 - 6.3e-09 35.4 0.0 1.2e-08 34.5 0.0 1.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01002731.1_2 - 8.6e-09 36.1 0.0 1.8e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 HlyD family secretion protein HlyD PF00529.20 AAAP01002731.1_2 - 1.1e-06 28.5 0.2 1.5e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Peptidase_A8 PF01252.18 AAAP01002732.1_2 - 1.1e-27 97.0 0.9 1.3e-27 96.8 0.9 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II Hydrolase PF00702.26 AAAP01002732.1_3 - 1.1e-13 52.0 0.4 1.1e-13 52.0 0.4 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01002732.1_3 - 0.00034 20.5 0.9 0.00047 20.0 0.9 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PDZ_2 PF13180.6 AAAP01002733.1_2 - 1.5e-11 44.4 0.0 2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AAAP01002733.1_2 - 3.1e-07 30.1 0.1 4.9e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 AAAP01002733.1_2 - 0.00021 21.6 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 AAAP01002733.1_2 - 0.029 14.3 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Tricorn protease PDZ domain HemolysinCabind PF00353.19 AAAP01002733.1_3 - 4.2e-22 77.8 68.4 1.4e-08 34.5 16.0 5.0 3 2 2 5 5 5 4 RTX calcium-binding nonapeptide repeat (4 copies) YdfA_immunity PF12127.8 AAAP01002733.1_3 - 0.036 13.2 0.3 8.4 5.4 0.2 2.5 2 1 1 3 3 3 0 SigmaW regulon antibacterial HATPase_c PF02518.26 AAAP01002734.1_1 - 3e-12 47.0 0.0 3.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAAP01002734.1_1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAAP01002734.1_1 - 0.043 13.6 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01002734.1_2 - 1.3e-15 57.5 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain AMP-binding PF00501.28 AAAP01002734.1_3 - 6.1e-32 110.7 0.2 7.1e-32 110.5 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF2635 PF10948.8 AAAP01002734.1_3 - 0.0006 19.5 0.0 0.0067 16.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2635) PCuAC PF04314.13 AAAP01002735.1_1 - 2.1e-18 66.1 0.0 2.4e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Copper chaperone PCu(A)C DUF1775 PF07987.11 AAAP01002735.1_2 - 9.5e-47 159.0 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) DUF2946 PF11162.8 AAAP01002735.1_3 - 1 10.0 17.2 1.3 9.7 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) BPL_LplA_LipB_2 PF16917.5 AAAP01002736.1_1 - 2.7e-24 85.7 0.0 3.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family VWA_3_C PF18571.1 AAAP01002736.1_1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain PSK_trans_fac PF07704.11 AAAP01002736.1_2 - 0.024 15.4 0.3 0.038 14.8 0.3 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor TRCF PF03461.15 AAAP01002736.1_2 - 0.18 12.2 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 TRCF domain APH PF01636.23 AAAP01002737.1_2 - 1.8e-17 64.1 1.6 2.7e-17 63.5 1.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAAP01002737.1_2 - 3.2e-15 56.3 0.0 1.1e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Inositol_P PF00459.25 AAAP01002737.1_3 - 3e-29 102.4 0.0 3.3e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Ald_Xan_dh_C2 PF02738.18 AAAP01002738.1_3 - 2.5e-80 270.5 1.8 2.8e-80 270.3 1.8 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase DmpG_comm PF07836.11 AAAP01002738.1_3 - 0.088 12.4 0.1 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 DmpG-like communication domain TetR_C_14 PF17754.1 AAAP01002738.1_3 - 0.14 12.1 0.8 2.8 7.9 0.1 3.1 4 0 0 4 4 4 0 MftR C-terminal domain PP_kinase_C_1 PF17941.1 AAAP01002739.1_1 - 3.2e-77 257.8 0.4 1e-75 252.8 0.1 2.8 3 0 0 3 3 3 1 Polyphosphate kinase C-terminal domain 1 PP_kinase PF02503.17 AAAP01002739.1_1 - 1.6e-63 213.9 0.0 3.4e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C PF13090.6 AAAP01002739.1_1 - 1.4e-61 207.0 0.0 9.1e-61 204.3 0.0 2.0 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PLDc_2 PF13091.6 AAAP01002739.1_1 - 1.2e-12 47.9 0.0 4e-05 23.5 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain DUF1206 PF06724.11 AAAP01002740.1_1 - 1.4 9.1 6.3 6.4 6.9 1.8 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) Gln-synt_C PF00120.24 AAAP01002741.1_1 - 2.6e-105 352.3 0.0 3e-105 352.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAAP01002741.1_1 - 0.03 14.1 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 AAAP01002741.1_1 - 0.12 12.2 0.1 1.6 8.6 0.1 2.3 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain PGK PF00162.19 AAAP01002742.1_1 - 0.013 14.5 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 Phosphoglycerate kinase F_bP_aldolase PF01116.20 AAAP01002742.1_2 - 5.4e-67 226.2 0.8 7.7e-67 225.7 0.8 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TMP-TENI PF02581.17 AAAP01002742.1_2 - 1e-15 57.5 0.0 2.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Acyl-CoA_dh_2 PF08028.11 AAAP01002743.1_1 - 5.6e-24 84.9 6.7 7.3e-24 84.6 6.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 AAAP01002743.1_1 - 1.5e-09 38.2 1.2 2.2e-09 37.7 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TruB_C PF09142.11 AAAP01002744.1_1 - 0.00091 19.0 0.1 0.0035 17.1 0.0 1.9 1 1 1 2 2 2 1 tRNA Pseudouridine synthase II, C terminal DNA_pol3_chi PF04364.13 AAAP01002744.1_2 - 2.2e-06 27.9 0.0 2.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC OMP_b-brl PF13505.6 AAAP01002744.1_3 - 0.45 10.6 10.6 1 9.5 10.6 1.6 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain GATase PF00117.28 AAAP01002744.1_4 - 3.2e-17 62.9 0.0 3.6e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01002744.1_4 - 1.5e-05 24.9 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 PAS_4 PF08448.10 AAAP01002745.1_1 - 4.3e-34 117.1 7.0 7e-14 52.0 0.3 3.9 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 AAAP01002745.1_1 - 1.2e-19 70.4 0.1 8.8e-18 64.4 0.0 3.2 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 AAAP01002745.1_1 - 2e-10 40.6 0.2 2e-10 40.6 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01002745.1_1 - 2e-08 34.4 0.0 9.9e-05 22.5 0.0 3.4 3 1 0 3 3 3 2 PAS domain PAS PF00989.25 AAAP01002745.1_1 - 1.2e-06 28.4 0.0 0.00018 21.5 0.0 3.7 4 1 0 4 4 4 1 PAS fold Oxidored_nitro PF00148.19 AAAP01002746.1_2 - 3e-84 283.1 0.0 3.6e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Acyl_transf_1 PF00698.21 AAAP01002747.1_1 - 3.6e-09 36.6 0.2 5.1e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain G_glu_transpept PF01019.21 AAAP01002748.1_1 - 7.3e-142 473.7 1.2 8.3e-142 473.5 1.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3809 PF12723.7 AAAP01002748.1_1 - 0.03 14.6 0.7 0.12 12.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3809) DUF2490 PF10677.9 AAAP01002749.1_2 - 9.6e-38 130.0 0.0 1.1e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) Methyltransf_12 PF08242.12 AAAP01002750.1_1 - 1.3e-11 45.0 0.0 2.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002750.1_1 - 1.5e-10 41.2 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 AAAP01002750.1_1 - 4.1e-10 39.9 0.0 7.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 AAAP01002750.1_1 - 2.3e-09 37.8 0.0 9.6e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002750.1_1 - 4.7e-09 36.8 0.0 2.5e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain AMP-binding_C PF13193.6 AAAP01002750.1_1 - 1.4e-05 26.0 0.0 3.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.6 AAAP01002750.1_1 - 0.0006 19.6 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Condensation PF00668.20 AAAP01002750.1_1 - 0.062 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Condensation domain NTP_transferase PF00483.23 AAAP01002751.1_2 - 2.9e-42 145.0 0.0 3.3e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01002751.1_2 - 2e-08 34.8 0.4 2.2e-08 34.6 0.4 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Docking PF08990.11 AAAP01002751.1_3 - 0.048 13.3 1.7 0.048 13.3 1.7 2.4 2 0 0 2 2 2 0 Erythronolide synthase docking Poly_export PF02563.16 AAAP01002751.1_4 - 7.3e-16 58.2 0.0 1.4e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AAAP01002751.1_4 - 1.8e-08 34.1 0.8 5.2e-08 32.6 0.8 1.8 1 0 0 1 1 1 1 SLBB domain GGDEF PF00990.21 AAAP01002753.1_1 - 1e-33 116.4 0.0 2.9e-33 114.9 0.0 1.8 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAAP01002753.1_1 - 4.6e-06 26.8 0.0 8.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PS_Dcarbxylase PF02666.15 AAAP01002753.1_2 - 1.4e-12 47.6 0.1 2.9e-11 43.3 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase CbiG_C PF01890.16 AAAP01002754.1_2 - 1.2e-21 77.4 6.7 1.5e-21 77.1 6.7 1.1 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus Cons_hypoth95 PF03602.15 AAAP01002754.1_3 - 2.8e-05 23.8 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 AAAP01002754.1_3 - 0.00046 21.2 0.0 0.00067 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AAAP01002754.1_3 - 0.0068 16.4 0.0 0.0084 16.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAAP01002754.1_3 - 0.015 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 AAAP01002754.1_3 - 0.019 15.7 0.0 0.027 15.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 AAAP01002754.1_3 - 0.11 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 AAAP01002754.1_3 - 0.14 11.6 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HTH_17 PF12728.7 AAAP01002755.1_2 - 3.9e-06 27.0 0.0 5.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01002755.1_2 - 4.5e-05 23.5 0.1 0.00011 22.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_Nu1 PF07471.12 AAAP01002755.1_2 - 4.6e-05 23.3 0.7 8.3e-05 22.4 0.7 1.4 1 1 0 1 1 1 1 Phage DNA packaging protein Nu1 HTH_29 PF13551.6 AAAP01002755.1_2 - 0.00035 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix DUF1323 PF07037.11 AAAP01002755.1_2 - 0.00062 20.2 0.0 0.00077 19.8 0.0 1.2 1 0 0 1 1 1 1 Putative transcription regulator (DUF1323) HTH_23 PF13384.6 AAAP01002755.1_2 - 0.0007 19.3 0.1 0.0015 18.3 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain Phage_Cox PF10743.9 AAAP01002755.1_2 - 0.019 15.0 0.1 0.044 13.9 0.1 1.6 1 1 0 1 1 1 0 Regulatory phage protein cox MerR_1 PF13411.6 AAAP01002755.1_2 - 0.026 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF1441 PF07278.11 AAAP01002755.1_2 - 0.062 13.2 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) YdaS_antitoxin PF15943.5 AAAP01002755.1_2 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_36 PF13730.6 AAAP01002755.1_2 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain BPD_transp_1 PF00528.22 AAAP01002756.1_1 - 1.6e-12 47.6 19.6 1.6e-12 47.6 19.6 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Wzy_C_2 PF11846.8 AAAP01002756.1_1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.3 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal IncE PF17627.2 AAAP01002756.1_1 - 2.1 8.4 5.4 3.4 7.7 1.7 2.5 2 0 0 2 2 2 0 Inclusion membrane protein E DUF4083 PF13314.6 AAAP01002756.1_1 - 4.8 7.2 5.0 37 4.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) ABC_membrane PF00664.23 AAAP01002757.1_2 - 2.9e-34 119.0 9.8 3.6e-34 118.7 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01002757.1_2 - 6.9e-08 33.1 0.1 1.2e-07 32.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 AAAP01002757.1_2 - 0.014 15.5 0.7 0.028 14.5 0.7 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 AAAP01002757.1_2 - 0.027 14.2 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 AAAP01002757.1_2 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CoA_binding PF02629.19 AAAP01002758.1_1 - 1.4e-29 102.6 0.2 1.4e-29 102.6 0.2 2.1 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 AAAP01002758.1_1 - 2.5e-19 69.6 0.8 4.1e-19 68.9 0.8 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AAAP01002758.1_1 - 1.8e-06 27.8 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAAP01002758.1_1 - 0.0011 19.4 0.2 0.0027 18.2 0.1 1.6 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AAAP01002758.1_2 - 0.00054 19.8 0.0 0.00062 19.6 0.0 1.0 1 0 0 1 1 1 1 CoA-ligase CheW PF01584.19 AAAP01002759.1_1 - 9.5e-09 35.0 0.2 1e-08 34.9 0.2 1.0 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AAAP01002759.1_2 - 1.8e-22 79.5 3.7 3.6e-15 55.8 0.5 2.9 2 1 1 3 3 3 2 CheW-like domain Response_reg PF00072.24 AAAP01002759.1_2 - 1.8e-17 63.5 0.0 6.4e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain SCAB-ABD PF16711.5 AAAP01002759.1_2 - 0.079 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Shikimate_dh_N PF08501.11 AAAP01002760.1_1 - 7e-29 99.9 0.0 9.9e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 AAAP01002760.1_1 - 1.2e-05 25.4 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAAP01002760.1_1 - 0.0014 19.2 0.1 0.0035 17.9 0.1 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 AAAP01002760.1_1 - 0.091 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase TonB_dep_Rec PF00593.24 AAAP01002761.1_1 - 2.2e-30 107.0 6.5 2.8e-30 106.6 6.5 1.1 1 0 0 1 1 1 1 TonB dependent receptor EF-hand_1 PF00036.32 AAAP01002761.1_2 - 2e-22 77.0 2.2 0.0002 20.7 0.1 4.2 2 1 2 4 4 4 4 EF hand EF-hand_6 PF13405.6 AAAP01002761.1_2 - 4e-18 63.7 4.0 0.00037 20.2 0.2 4.3 2 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 AAAP01002761.1_2 - 2.7e-16 58.2 5.6 0.00066 19.1 0.0 4.2 3 1 1 4 4 4 4 EF hand EF-hand_7 PF13499.6 AAAP01002761.1_2 - 3.8e-13 49.7 2.1 0.00082 19.8 1.1 4.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 AAAP01002761.1_2 - 5.2e-13 48.6 0.1 0.028 14.2 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain pair Excalibur PF05901.11 AAAP01002761.1_2 - 1e-05 26.1 3.9 1.8 9.2 0.1 4.2 4 0 0 4 4 4 2 Excalibur calcium-binding domain SPARC_Ca_bdg PF10591.9 AAAP01002761.1_2 - 0.0003 21.1 1.6 0.72 10.2 0.6 3.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 AAAP01002761.1_2 - 0.082 12.8 0.2 53 3.8 0.0 3.0 3 0 0 3 3 3 0 EF hand EF-hand_9 PF14658.6 AAAP01002761.1_2 - 0.18 12.2 3.9 15 6.0 0.7 3.7 2 1 1 3 3 3 0 EF-hand domain Sugarporin_N PF11471.8 AAAP01002761.1_3 - 0.059 13.3 0.2 0.059 13.3 0.2 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Trypsin PF00089.26 AAAP01002762.1_1 - 1.1e-26 94.0 0.0 1.3e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 AAAP01002762.1_1 - 1.6e-11 45.3 0.9 2.4e-11 44.7 0.9 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S55 PF05580.12 AAAP01002762.1_1 - 0.029 14.3 0.4 0.053 13.5 0.1 1.5 2 0 0 2 2 2 0 SpoIVB peptidase S55 Toxin_4 PF00706.17 AAAP01002762.1_1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Anenome neurotoxin Phage_capsid PF05065.13 AAAP01002762.1_2 - 2.7e-79 266.4 0.1 3e-79 266.2 0.1 1.0 1 0 0 1 1 1 1 Phage capsid family ACT_4 PF13291.6 AAAP01002763.1_1 - 5.3e-10 39.8 0.5 5.7e-10 39.6 0.5 1.0 1 0 0 1 1 1 1 ACT domain Pribosyltran PF00156.27 AAAP01002763.1_2 - 8.7e-18 64.3 0.0 1.7e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NYN PF01936.18 AAAP01002763.1_3 - 7.6e-09 36.2 0.1 8.4e-09 36.1 0.1 1.0 1 0 0 1 1 1 1 NYN domain NYN PF01936.18 AAAP01002763.1_4 - 1.7e-22 80.5 0.1 2.1e-22 80.2 0.1 1.0 1 0 0 1 1 1 1 NYN domain Inositol_P PF00459.25 AAAP01002764.1_2 - 1.3e-38 133.0 0.0 1.6e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family YAcAr PF10686.9 AAAP01002765.1_1 - 5e-28 96.9 0.0 1.1e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 YspA, cpYpsA-related SLOG family adh_short_C2 PF13561.6 AAAP01002765.1_3 - 1.4e-31 109.9 0.0 1.5e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002765.1_3 - 2.5e-15 56.5 0.0 2.8e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1194 PF06707.11 AAAP01002766.1_1 - 2.1e-05 23.8 0.0 2.3e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) DIOX_N PF14226.6 AAAP01002766.1_2 - 6e-35 120.5 0.0 9.4e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 AAAP01002766.1_2 - 1.2e-19 70.6 0.0 1.8e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 AAAP01002767.1_2 - 4.6e-06 27.4 10.2 4.6e-06 27.4 10.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01002767.1_2 - 0.0059 15.9 0.0 0.031 13.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 ABC_tran_CTD PF16326.5 AAAP01002767.1_3 - 4.8e-11 42.7 3.2 6.5e-11 42.3 3.2 1.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain BLOC1_2 PF10046.9 AAAP01002767.1_3 - 0.0078 16.5 0.1 0.02 15.2 0.0 1.6 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 AAAP01002767.1_3 - 0.027 14.5 0.1 0.034 14.2 0.1 1.3 1 1 0 1 1 1 0 Laminin Domain II SOGA PF11365.8 AAAP01002767.1_3 - 0.03 15.5 0.2 0.035 15.2 0.2 1.1 1 0 0 1 1 1 0 Protein SOGA NPV_P10 PF05531.12 AAAP01002767.1_3 - 0.13 12.7 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Vps53_N PF04100.12 AAAP01002767.1_3 - 0.15 11.0 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal SlyX PF04102.12 AAAP01002767.1_3 - 0.17 12.6 0.3 0.24 12.1 0.3 1.3 1 1 0 1 1 1 0 SlyX CheR_N PF03705.15 AAAP01002769.1_1 - 2.1e-10 40.1 3.2 4.1e-10 39.2 3.2 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain CheR PF01739.18 AAAP01002769.1_1 - 5.5e-08 32.5 0.0 8.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain HEAT_2 PF13646.6 AAAP01002769.1_2 - 2.4e-19 69.5 9.0 5.1e-09 36.4 0.2 2.2 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 AAAP01002769.1_2 - 1.6e-06 27.9 1.3 1.1 9.7 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.16 AAAP01002769.1_2 - 0.004 17.7 12.6 0.0094 16.5 0.2 4.8 6 1 1 7 7 7 1 PBS lyase HEAT-like repeat IFRD PF05004.13 AAAP01002769.1_2 - 0.087 11.9 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 AAAP01002769.1_2 - 0.13 10.8 0.0 6 5.3 0.0 2.6 1 1 2 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.6 AAAP01002769.1_2 - 3.2 8.4 10.4 5.2 7.7 2.4 3.8 3 1 1 4 4 4 0 HEAT-like repeat CheB_methylest PF01339.17 AAAP01002769.1_3 - 6.4e-05 22.8 0.0 6.8e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 CheB methylesterase DUF262 PF03235.14 AAAP01002770.1_1 - 1.9e-07 31.5 0.0 3.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF262 DUF1524 PF07510.11 AAAP01002770.1_1 - 2.8e-06 27.3 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 AAAP01002770.1_1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease HNH PF01844.23 AAAP01002770.1_1 - 0.23 11.7 0.0 0.5 10.6 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease MoCF_biosynth PF00994.24 AAAP01002771.1_1 - 6.8e-29 100.4 0.0 7.9e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain Hpt PF01627.23 AAAP01002772.1_1 - 9.9e-16 57.8 1.2 1.2e-15 57.5 0.1 1.7 2 0 0 2 2 2 1 Hpt domain Neisseria_TspB PF05616.13 AAAP01002772.1_1 - 2.1 6.8 7.3 17 3.8 6.9 1.9 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein Rotamase_3 PF13616.6 AAAP01002773.1_2 - 1.6e-28 99.6 0.0 3.1e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAAP01002773.1_2 - 3.6e-25 88.8 0.1 1.4e-24 86.9 0.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAAP01002773.1_2 - 6e-23 82.0 1.3 6e-23 82.0 1.3 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain TrbI_Ftype PF09677.10 AAAP01002773.1_2 - 0.0048 17.2 0.4 0.22 11.8 0.1 2.2 2 0 0 2 2 2 1 Type-F conjugative transfer system protein (TrbI_Ftype) NTPase_I-T PF01931.18 AAAP01002773.1_2 - 0.068 13.0 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF84 Flg_bb_rod PF00460.20 AAAP01002774.1_1 - 0.0031 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAAP01002774.1_1 - 0.088 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Flg_bbr_C PF06429.13 AAAP01002774.1_2 - 1.9e-07 31.1 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01002774.1_2 - 1.8e-06 27.7 0.7 1.8e-06 27.7 0.7 1.8 2 0 0 2 2 2 1 Flagella basal body rod protein FliE PF02049.18 AAAP01002774.1_3 - 5.5e-23 80.9 0.2 6.7e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE Phage-MuB_C PF09077.11 AAAP01002774.1_3 - 0.032 14.1 1.4 0.11 12.4 0.9 1.8 1 1 1 2 2 2 0 Mu B transposition protein, C terminal Bac_export_3 PF01313.19 AAAP01002774.1_4 - 4.5e-17 61.7 3.6 4.9e-17 61.6 3.6 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 BPD_transp_2 PF02653.16 AAAP01002775.1_1 - 1.1e-09 37.9 6.7 1.2e-09 37.7 6.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Alpha_GJ PF03229.13 AAAP01002775.1_1 - 2.4 8.7 4.6 34 5.0 0.1 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J PRA1 PF03208.19 AAAP01002775.1_1 - 9.1 5.9 7.4 2.1 8.0 3.3 1.8 2 0 0 2 2 2 0 PRA1 family protein Peripla_BP_6 PF13458.6 AAAP01002775.1_2 - 2.4e-63 214.9 0.0 3e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein GreA_GreB_N PF03449.15 AAAP01002776.1_1 - 1.6e-29 101.8 4.8 2.4e-29 101.3 4.8 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AAAP01002776.1_1 - 5.8e-28 96.6 0.5 8.9e-28 96.0 0.5 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term CDC48_N PF02359.18 AAAP01002776.1_1 - 0.045 13.9 0.2 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Mito_fiss_Elm1 PF06258.11 AAAP01002776.1_3 - 1.7e-42 145.7 0.0 1.9e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 FliM PF02154.15 AAAP01002777.1_1 - 1.3e-57 194.9 0.0 1.7e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AAAP01002777.1_1 - 7.2e-18 64.4 0.0 1.4e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term HrpB7 PF09486.10 AAAP01002777.1_2 - 0.04 14.3 0.6 0.04 14.3 0.6 1.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Delta_lysin PF05372.11 AAAP01002777.1_2 - 0.34 10.2 2.4 1.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Delta lysin family Biotin_lipoyl_2 PF13533.6 AAAP01002778.1_2 - 8.2e-12 44.8 0.4 3.7e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAAP01002778.1_2 - 0.0057 15.9 0.2 0.018 14.2 0.0 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01002778.1_2 - 0.025 15.3 0.1 0.046 14.4 0.1 1.5 1 0 0 1 1 1 0 HlyD family secretion protein PDZ_2 PF13180.6 AAAP01002779.1_1 - 3.9e-12 46.3 0.2 4.6e-12 46.1 0.2 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AAAP01002779.1_1 - 1.2e-08 34.6 2.5 0.003 17.4 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AAAP01002779.1_1 - 4.8e-07 30.0 0.2 2.1e-06 28.0 0.2 1.8 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 AAAP01002779.1_1 - 0.00033 21.0 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 AAAP01002779.1_1 - 0.049 13.6 0.4 0.081 12.9 0.3 1.6 1 1 0 1 1 1 0 Tricorn protease PDZ domain DnaJ PF00226.31 AAAP01002779.1_2 - 1.8e-07 31.2 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 AAAP01002779.1_2 - 0.018 15.1 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Pam16 MM_CoA_mutase PF01642.22 AAAP01002780.1_1 - 0.012 14.2 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase PIN_10 PF18478.1 AAAP01002780.1_1 - 0.054 13.7 0.2 0.48 10.7 0.1 2.3 1 1 2 3 3 3 0 PIN like domain MM_CoA_mutase PF01642.22 AAAP01002780.1_2 - 1.1e-67 228.7 0.7 1.4e-67 228.5 0.7 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase MEDS PF14417.6 AAAP01002780.1_2 - 0.096 12.5 0.3 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HTH_39 PF14090.6 AAAP01002781.1_1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Plug PF07715.15 AAAP01002781.1_2 - 1e-15 58.2 0.5 3e-15 56.7 0.5 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AAAP01002781.1_2 - 1.8e-07 31.4 18.2 2.7e-07 30.8 17.9 1.4 1 1 0 1 1 1 1 TonB dependent receptor Transposase_20 PF02371.16 AAAP01002782.1_1 - 1.6e-25 89.2 0.0 5e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAAP01002782.1_1 - 2.2e-19 69.8 0.1 4.3e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Transposase PAS PF00989.25 AAAP01002783.1_1 - 2.9e-26 91.7 0.0 1.6e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01002783.1_1 - 9e-16 58.0 0.0 4.3e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAAP01002783.1_1 - 2.1e-13 50.5 1.1 1.1e-08 35.3 0.1 2.3 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01002783.1_1 - 2.1e-07 30.8 0.0 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain HisKA PF00512.25 AAAP01002783.1_1 - 0.0074 16.3 0.2 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain TniB PF05621.11 AAAP01002783.1_1 - 0.022 14.2 0.0 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Amidohydro_1 PF01979.20 AAAP01002783.1_2 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01002783.1_2 - 8.6e-07 28.8 2.2 5.2e-06 26.2 2.2 2.0 1 1 0 1 1 1 1 Amidohydrolase family Usp PF00582.26 AAAP01002783.1_2 - 0.0076 16.8 0.1 0.015 15.8 0.1 1.5 1 0 0 1 1 1 1 Universal stress protein family Metallophos_2 PF12850.7 AAAP01002784.1_1 - 4e-05 23.9 0.1 6.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAAP01002784.1_1 - 4.3e-05 24.1 0.0 7.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RelB_transactiv PF16181.5 AAAP01002784.1_2 - 0.11 12.7 2.0 0.14 12.5 2.0 1.2 1 0 0 1 1 1 0 RelB transactivation domain AAA_2 PF07724.14 AAAP01002785.1_1 - 2e-32 112.7 0.0 7.2e-28 97.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAAP01002785.1_1 - 1.2e-27 95.9 1.4 1.7e-27 95.4 0.3 1.9 2 0 0 2 2 1 1 AAA lid domain AAA PF00004.29 AAAP01002785.1_1 - 8.5e-26 90.9 0.0 1e-13 51.9 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01002785.1_1 - 1.5e-17 63.9 0.0 9.3e-10 38.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01002785.1_1 - 9.7e-12 45.6 2.0 1.7e-05 25.3 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 AAAP01002785.1_1 - 4.2e-09 36.8 0.6 0.012 15.8 0.2 4.0 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 AAAP01002785.1_1 - 3.5e-08 33.4 0.0 0.0058 16.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 AAAP01002785.1_1 - 2.2e-07 30.8 2.5 0.029 14.1 0.0 3.8 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AAAP01002785.1_1 - 2.7e-07 31.2 0.0 0.038 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AAAP01002785.1_1 - 1.8e-06 27.6 0.0 0.03 13.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAAP01002785.1_1 - 1.9e-06 27.8 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 AAAP01002785.1_1 - 2.3e-06 27.7 0.0 0.02 14.9 0.0 2.8 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 AAAP01002785.1_1 - 3e-06 26.8 0.0 0.01 15.3 0.0 3.6 2 2 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 AAAP01002785.1_1 - 1.1e-05 25.6 0.0 0.04 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_6 PF12774.7 AAAP01002785.1_1 - 1.1e-05 24.5 0.0 0.00011 21.3 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region TIP49 PF06068.13 AAAP01002785.1_1 - 1.6e-05 24.3 0.1 0.011 15.0 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 AAAP01002785.1_1 - 2.2e-05 24.8 0.0 0.23 11.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 AAAP01002785.1_1 - 3.6e-05 23.1 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ResIII PF04851.15 AAAP01002785.1_1 - 4.4e-05 23.6 0.0 0.13 12.2 0.0 3.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit NACHT PF05729.12 AAAP01002785.1_1 - 4.4e-05 23.4 0.0 0.007 16.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 AAAP01002785.1_1 - 5.5e-05 23.2 0.0 0.56 10.2 0.0 2.6 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 AAAP01002785.1_1 - 8.2e-05 22.1 0.2 0.21 10.9 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAAP01002785.1_1 - 0.00016 21.6 0.1 0.22 11.4 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AAAP01002785.1_1 - 0.00023 20.8 0.1 0.41 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.6 AAAP01002785.1_1 - 0.0012 19.2 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 AAAP01002785.1_1 - 0.0013 18.5 0.1 0.21 11.4 0.0 3.4 4 0 0 4 4 4 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 AAAP01002785.1_1 - 0.0022 18.3 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 AAAP01002785.1_1 - 0.0059 16.2 0.1 2.9 7.5 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AAAP01002785.1_1 - 0.0083 15.9 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AAAP01002785.1_1 - 0.013 15.4 0.1 11 5.9 0.0 3.4 4 0 0 4 4 4 0 NTPase RsgA_GTPase PF03193.16 AAAP01002785.1_1 - 0.015 15.2 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 AAAP01002785.1_1 - 0.021 14.6 2.1 0.43 10.3 0.0 2.9 3 1 1 4 4 3 0 AAA domain IPT PF01745.16 AAAP01002785.1_1 - 0.028 13.8 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase Roc PF08477.13 AAAP01002785.1_1 - 0.033 14.4 0.0 0.84 9.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 AAAP01002785.1_1 - 0.038 13.9 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 AAAP01002785.1_1 - 0.051 13.3 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DnaB_C PF03796.15 AAAP01002785.1_1 - 0.059 12.7 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PanZ PF12568.8 AAAP01002785.1_1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Torsin PF06309.11 AAAP01002785.1_1 - 0.079 13.1 0.0 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 Torsin NB-ARC PF00931.22 AAAP01002785.1_1 - 0.087 12.0 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.23 AAAP01002785.1_1 - 0.11 11.6 0.2 0.78 8.8 0.0 2.4 3 0 0 3 3 3 0 MCM P-loop domain CbiA PF01656.23 AAAP01002785.1_1 - 0.11 12.5 0.2 16 5.6 0.0 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 AAAP01002785.1_1 - 0.19 12.1 2.7 1.2 9.5 0.1 3.2 2 2 1 3 3 3 0 AAA domain DUF2269 PF10027.9 AAAP01002786.1_3 - 0.35 10.9 7.6 0.11 12.6 4.7 1.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) CbiQ PF02361.16 AAAP01002786.1_3 - 2.4 7.7 10.7 0.71 9.5 5.1 1.9 1 1 1 2 2 2 0 Cobalt transport protein MarR_2 PF12802.7 AAAP01002786.1_4 - 1.6e-09 37.5 0.1 3.7e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01002786.1_4 - 9.6e-09 35.1 0.0 3.8e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAAP01002786.1_4 - 2.8e-08 34.1 0.0 5.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 AAAP01002786.1_4 - 0.004 17.0 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 AAAP01002786.1_4 - 0.0043 16.9 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 AAAP01002786.1_4 - 0.077 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family P5CR_dimer PF14748.6 AAAP01002786.1_5 - 0.0079 16.4 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Glyco_hydro_15 PF00723.21 AAAP01002787.1_1 - 1.5e-29 103.1 0.0 2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 MFS_1 PF07690.16 AAAP01002788.1_1 - 2.4e-11 43.2 22.9 3.1e-11 42.8 22.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DHHC PF01529.20 AAAP01002788.1_1 - 0.3 11.2 3.1 2.5 8.2 2.1 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase TPP_enzyme_N PF02776.18 AAAP01002788.1_2 - 3.5e-46 156.9 0.0 5.7e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAAP01002788.1_2 - 0.0017 18.1 0.1 0.0041 16.8 0.1 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cys_Met_Meta_PP PF01053.20 AAAP01002788.1_2 - 0.22 10.0 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ald_Xan_dh_C2 PF02738.18 AAAP01002789.1_1 - 5e-89 299.2 0.1 6.2e-89 298.9 0.1 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01002789.1_1 - 9.3e-10 38.9 0.2 2.9e-09 37.2 0.2 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Beta_helix PF13229.6 AAAP01002790.1_1 - 5.8e-14 52.2 24.6 1.7e-10 41.0 11.7 1.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 AAAP01002790.1_1 - 0.00027 20.3 7.6 0.00056 19.3 2.1 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 AAAP01002790.1_1 - 0.0066 16.3 1.8 0.0066 16.3 1.8 1.7 2 1 0 2 2 2 1 Pectate lyase superfamily protein Peptidase_M23 PF01551.22 AAAP01002790.1_1 - 0.055 13.7 0.3 0.24 11.6 0.3 2.0 1 1 0 1 1 1 0 Peptidase family M23 Glyco_hydro_28 PF00295.17 AAAP01002790.1_1 - 0.45 9.5 10.9 1.4 7.9 0.7 2.4 1 1 1 3 3 3 0 Glycosyl hydrolases family 28 HemolysinCabind PF00353.19 AAAP01002790.1_2 - 7.3e-15 54.6 42.9 1.5e-07 31.3 13.1 4.1 3 1 2 5 5 5 3 RTX calcium-binding nonapeptide repeat (4 copies) K_trans PF02705.16 AAAP01002791.1_1 - 1.7e-149 498.7 13.6 2e-149 498.6 13.6 1.0 1 0 0 1 1 1 1 K+ potassium transporter Metallophos PF00149.28 AAAP01002792.1_1 - 2.2e-06 28.3 2.4 3.8e-06 27.5 0.1 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01002792.1_1 - 4.4e-06 27.0 0.2 9e-06 26.0 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LemA PF04011.12 AAAP01002793.1_1 - 1.5e-59 200.1 0.6 1.7e-59 200.0 0.6 1.0 1 0 0 1 1 1 1 LemA family TPR_15 PF13429.6 AAAP01002793.1_1 - 0.0034 16.7 0.7 0.004 16.4 0.1 1.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Gastrin PF00918.17 AAAP01002793.1_1 - 0.17 12.9 0.5 0.24 12.4 0.5 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family TPM_phosphatase PF04536.14 AAAP01002793.1_2 - 2e-41 141.0 0.0 2.8e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 TPM domain DUF5130 PF17174.4 AAAP01002793.1_2 - 0.00017 21.8 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) MOLO1 PF17175.4 AAAP01002793.1_2 - 0.18 12.0 0.0 0.61 10.2 0.0 1.8 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 FHIPEP PF00771.20 AAAP01002794.1_1 - 5.3e-257 854.6 5.2 6e-257 854.4 5.2 1.0 1 0 0 1 1 1 1 FHIPEP family HHH_3 PF12836.7 AAAP01002795.1_1 - 5.9e-13 48.9 0.0 8.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.11 AAAP01002795.1_1 - 0.05 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) FAP PF07174.11 AAAP01002795.1_1 - 4.6 6.6 27.4 5.8 6.3 27.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3016 PF11454.8 AAAP01002795.1_3 - 6.8e-08 32.4 0.0 8.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3016) FAD_binding_4 PF01565.23 AAAP01002796.1_1 - 7.9e-06 25.7 0.0 9.8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Competence PF03772.16 AAAP01002796.1_2 - 0.11 11.8 9.8 0.29 10.4 9.7 1.8 1 1 0 1 1 1 0 Competence protein rve PF00665.26 AAAP01002797.1_1 - 0.0039 17.4 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Molydop_binding PF01568.21 AAAP01002798.1_1 - 1.2e-23 83.2 0.0 1.9e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain NO_synthase PF02898.15 AAAP01002798.1_1 - 0.23 10.4 0.3 28 3.6 0.0 2.8 2 1 1 3 3 3 0 Nitric oxide synthase, oxygenase domain Fer4_7 PF12838.7 AAAP01002798.1_2 - 1.1e-09 38.8 17.5 6.7e-06 26.6 15.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01002798.1_2 - 1.5e-07 31.4 19.0 0.00039 20.5 14.9 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01002798.1_2 - 5.3e-07 29.7 17.7 0.0013 18.8 14.2 2.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_11 PF13247.6 AAAP01002798.1_2 - 8.2e-07 29.1 3.9 8.2e-07 29.1 3.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01002798.1_2 - 5.5e-06 26.4 20.3 0.013 15.6 17.0 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01002798.1_2 - 3e-05 23.9 23.8 0.0046 17.0 6.7 3.6 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4 PF00037.27 AAAP01002798.1_2 - 3.7e-05 23.3 28.1 0.0018 18.0 5.1 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01002798.1_2 - 0.00013 21.8 29.8 0.045 13.8 8.1 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01002798.1_2 - 0.0002 21.7 17.5 0.12 12.9 13.6 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01002798.1_2 - 0.0002 21.8 15.0 0.43 11.1 5.2 3.2 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01002798.1_2 - 0.00067 20.4 29.9 0.17 12.9 0.4 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01002798.1_2 - 0.0053 17.7 17.9 3.6 8.6 3.2 3.2 2 1 1 3 3 3 3 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAAP01002798.1_2 - 0.011 16.2 3.0 0.011 16.2 3.0 3.8 4 1 0 4 4 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 AAAP01002798.1_2 - 0.037 14.7 14.0 4.7 8.0 11.8 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_5 PF12801.7 AAAP01002798.1_2 - 2.4 8.2 6.4 1.6 8.7 2.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 AAAP01002798.1_2 - 6.8 6.5 22.1 2.2 8.1 4.6 2.5 2 1 0 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster GPP34 PF05719.11 AAAP01002799.1_1 - 8.7e-39 133.7 14.7 1.1e-38 133.3 14.7 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SIMPL PF04402.14 AAAP01002799.1_2 - 1.7e-34 120.0 5.3 1.9e-34 119.9 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Aminotran_1_2 PF00155.21 AAAP01002800.1_1 - 3.1e-24 85.9 0.0 3.6e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TDP43_N PF18694.1 AAAP01002800.1_1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain Alpha-amylase PF00128.24 AAAP01002801.1_1 - 5e-10 39.5 0.0 1.9e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.6 AAAP01002801.1_1 - 3.1e-05 24.2 0.0 5.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 hDGE_amylase PF14701.6 AAAP01002801.1_1 - 0.0021 17.2 0.0 1.4 8.0 0.0 2.4 2 1 0 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain Dynein_attach_N PF15867.5 AAAP01002801.1_1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus Alpha-amylase PF00128.24 AAAP01002801.1_2 - 3.7e-68 230.6 0.1 4.1e-68 230.4 0.1 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 AAAP01002801.1_2 - 0.0009 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Cellulase PF00150.18 AAAP01002801.1_2 - 0.0019 17.7 0.0 0.047 13.1 0.0 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_77 PF02446.17 AAAP01002801.1_2 - 0.019 13.8 0.0 0.064 12.1 0.0 1.7 1 1 0 1 1 1 0 4-alpha-glucanotransferase Glyco_hydro_70 PF02324.16 AAAP01002801.1_2 - 0.18 9.9 0.0 0.27 9.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 HisKA PF00512.25 AAAP01002802.1_1 - 1.6e-18 66.5 0.2 5.4e-18 64.8 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01002802.1_1 - 8.6e-12 45.2 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AAAP01002802.1_1 - 1e-06 29.2 0.0 2.4e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAAP01002802.1_1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain SMC_N PF02463.19 AAAP01002803.1_1 - 0.0065 15.9 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain LSDAT_prok PF18171.1 AAAP01002803.1_1 - 0.13 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote BBP2 PF07642.11 AAAP01002804.1_1 - 1e-55 189.3 16.0 1.2e-55 189.1 16.0 1.0 1 0 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 AA_permease_2 PF13520.6 AAAP01002805.1_2 - 7e-30 104.2 13.7 9.3e-30 103.8 13.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01002805.1_2 - 2.2e-23 82.6 11.2 2.6e-23 82.4 11.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 AAAP01002805.1_2 - 0.00021 21.3 1.4 0.00021 21.3 1.4 3.6 4 0 0 4 4 4 1 C-terminus of AA_permease GMC_oxred_N PF00732.19 AAAP01002806.1_1 - 4.8e-45 154.2 0.0 5.9e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 AAAP01002806.1_1 - 1.2e-05 24.6 6.3 1.8e-05 24.0 6.3 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAAP01002806.1_1 - 0.00022 20.4 1.7 0.00033 19.8 1.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAAP01002806.1_1 - 0.0018 18.4 0.8 0.0062 16.7 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01002806.1_1 - 0.0023 17.2 0.9 0.0034 16.6 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01002806.1_1 - 0.0098 15.2 0.6 0.013 14.7 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAAP01002806.1_1 - 0.017 14.2 2.9 0.024 13.7 2.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01002806.1_1 - 0.018 14.4 4.1 0.027 13.8 4.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 AAAP01002806.1_1 - 0.028 14.0 0.7 0.061 13.0 0.7 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GDI PF00996.18 AAAP01002806.1_1 - 0.029 12.9 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.14 AAAP01002806.1_1 - 0.051 12.3 0.9 0.067 11.9 0.9 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 AAAP01002806.1_1 - 0.051 14.1 0.2 0.11 13.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01002806.1_1 - 0.079 12.5 10.3 0.33 10.5 10.2 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 AAAP01002806.1_1 - 0.11 11.8 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family TPP_enzyme_C PF02775.21 AAAP01002806.1_2 - 3.3e-13 49.7 0.0 5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TRI12 PF06609.13 AAAP01002806.1_3 - 0.06 11.8 0.5 0.061 11.7 0.5 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Phenol_MetA_deg PF13557.6 AAAP01002807.1_1 - 2.2e-20 73.6 0.6 3.1e-20 73.2 0.6 1.2 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation Porin_OmpG_1_2 PF16946.5 AAAP01002807.1_1 - 0.098 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 OMPG-porin 1 family AsnC_trans_reg PF01037.21 AAAP01002807.1_2 - 5e-09 36.0 0.1 5.6e-09 35.8 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_29 PF13551.6 AAAP01002807.1_3 - 0.00023 21.1 0.1 0.00041 20.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAAP01002807.1_3 - 0.0014 18.7 0.9 0.0023 18.0 0.9 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01002807.1_3 - 0.002 17.9 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 AAAP01002807.1_3 - 0.06 14.0 4.9 0.17 12.5 1.4 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_WhiA PF02650.14 AAAP01002807.1_3 - 0.07 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 WhiA C-terminal HTH domain FTHFS PF01268.19 AAAP01002808.1_1 - 1.8e-179 597.5 0.3 2.2e-179 597.3 0.3 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 AAAP01002808.1_1 - 0.032 14.3 0.2 0.065 13.3 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HMA PF00403.26 AAAP01002808.1_2 - 2.7e-08 34.1 0.0 3.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain MlrC_C PF07171.12 AAAP01002808.1_2 - 0.0032 17.7 0.4 0.0041 17.3 0.4 1.1 1 0 0 1 1 1 1 MlrC C-terminus Aminotran_1_2 PF00155.21 AAAP01002809.1_1 - 3.5e-78 263.3 0.0 4e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAAP01002809.1_1 - 2.4e-11 43.5 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAAP01002809.1_1 - 0.0031 16.1 0.0 0.0054 15.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 AAAP01002809.1_1 - 0.0086 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase OKR_DC_1 PF01276.20 AAAP01002809.1_1 - 0.031 13.0 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 AAAP01002809.1_1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Glyco_hydro_92 PF07971.12 AAAP01002810.1_1 - 1.5e-96 324.1 0.0 1.8e-96 323.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 CBM-like PF14683.6 AAAP01002810.1_1 - 0.066 13.1 0.0 1.8 8.5 0.0 2.6 2 1 1 3 3 3 0 Polysaccharide lyase family 4, domain III YfhD PF14151.6 AAAP01002810.1_3 - 0.071 13.3 0.4 0.08 13.1 0.4 1.1 1 0 0 1 1 1 0 YfhD-like protein Catalase PF00199.19 AAAP01002811.1_1 - 2.3e-87 293.6 0.4 2.5e-87 293.5 0.4 1.0 1 0 0 1 1 1 1 Catalase LysR_substrate PF03466.20 AAAP01002811.1_2 - 7.6e-41 139.8 8.0 7.6e-41 139.8 8.0 1.5 1 1 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01002811.1_2 - 2.1e-21 75.6 0.2 2.1e-21 75.6 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAAP01002811.1_2 - 0.013 15.3 0.4 0.052 13.4 0.0 2.2 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAAP01002811.1_2 - 0.051 13.5 1.3 0.13 12.2 0.1 2.5 2 1 0 2 2 2 0 MarR family HTH_24 PF13412.6 AAAP01002811.1_2 - 0.054 13.1 0.2 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding APH PF01636.23 AAAP01002812.1_1 - 8e-36 124.2 0.4 1e-35 123.8 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAAP01002812.1_1 - 0.0055 16.3 0.1 0.0084 15.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase BPD_transp_1 PF00528.22 AAAP01002813.1_1 - 1e-13 51.4 8.0 1.4e-13 51.0 8.0 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01002813.1_2 - 6.9e-34 117.3 0.0 1.2e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002813.1_2 - 3.5e-11 43.5 0.2 0.00025 21.0 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01002813.1_2 - 2.7e-08 33.5 0.0 4.7e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAAP01002813.1_2 - 3.5e-06 27.3 0.0 9.8e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01002813.1_2 - 9.9e-06 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01002813.1_2 - 1.4e-05 25.7 0.1 2e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01002813.1_2 - 0.00014 21.7 0.0 0.00037 20.3 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 AAAP01002813.1_2 - 0.00022 21.7 0.1 0.00063 20.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01002813.1_2 - 0.00032 20.6 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 AAAP01002813.1_2 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AAAP01002813.1_2 - 0.0042 16.8 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AAAP01002813.1_2 - 0.017 14.6 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 AAAP01002813.1_2 - 0.031 14.0 0.0 0.12 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AAAP01002813.1_2 - 0.04 13.9 0.0 0.15 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AAAP01002813.1_2 - 0.046 13.3 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAAP01002813.1_2 - 0.047 12.9 0.0 0.05 12.8 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit PRK PF00485.18 AAAP01002813.1_2 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AAAP01002813.1_2 - 0.062 13.5 0.2 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 AAAP01002813.1_2 - 0.062 12.1 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein SbcCD_C PF13558.6 AAAP01002813.1_2 - 0.074 13.3 0.2 2 8.7 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 AAAP01002813.1_2 - 0.076 13.4 0.1 1.9 8.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAAP01002813.1_2 - 0.081 12.8 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 AAAP01002813.1_2 - 0.089 12.8 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AAAP01002813.1_2 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAAP01002813.1_2 - 0.17 11.5 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 AAAP01002813.1_2 - 0.17 12.3 0.0 5.1 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAAP01002813.1_2 - 0.17 11.0 0.0 0.35 10.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 AAAP01002813.1_2 - 0.19 11.6 0.1 0.35 10.8 0.0 1.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PhoU PF01895.19 AAAP01002813.1_3 - 1.2e-06 28.9 0.3 1.7e-06 28.4 0.3 1.3 1 0 0 1 1 1 1 PhoU domain tRNA-synt_1 PF00133.22 AAAP01002814.1_1 - 0.0043 15.4 0.0 0.0043 15.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) KAsynt_C_assoc PF16197.5 AAAP01002815.1_1 - 8.4e-16 58.4 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension GyrI-like PF06445.15 AAAP01002816.1_1 - 4.2e-07 30.4 0.0 6.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AAAP01002816.1_1 - 1.8e-06 28.2 0.0 2.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Integron-associated effector binding protein DAP_epimerase PF01678.19 AAAP01002816.1_2 - 2.7e-12 46.9 0.0 3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Diaminopimelate epimerase Pro_racemase PF05544.11 AAAP01002816.1_2 - 0.0002 20.6 0.0 0.00021 20.4 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 AAAP01002816.1_2 - 0.015 14.8 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Clostridium_P47 PF06597.11 AAAP01002816.1_2 - 0.032 13.0 0.0 0.034 12.9 0.0 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein PhaG_MnhG_YufB PF03334.14 AAAP01002817.1_2 - 3.1e-09 36.9 10.0 3.7e-09 36.7 10.0 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit DUF2975 PF11188.8 AAAP01002817.1_2 - 1.1 9.1 7.4 3.1 7.7 7.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DoxX_2 PF13564.6 AAAP01002817.1_2 - 1.2 9.3 12.8 2.5 8.2 12.8 1.6 1 1 0 1 1 1 0 DoxX-like family BPD_transp_2 PF02653.16 AAAP01002817.1_2 - 1.6 7.8 10.6 0.23 10.6 5.8 1.7 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component DUF4040 PF13244.6 AAAP01002817.1_3 - 4.8e-15 55.5 6.3 4.8e-15 55.5 6.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4040) DUF4131 PF13567.6 AAAP01002817.1_3 - 2.6 7.7 8.4 0.39 10.3 4.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MnhB PF04039.13 AAAP01002817.1_4 - 5.8e-19 68.6 11.5 5.8e-19 68.6 11.5 1.8 2 1 1 3 3 3 1 Domain related to MnhB subunit of Na+/H+ antiporter Melittin PF01372.17 AAAP01002817.1_4 - 0.24 11.4 0.9 0.9 9.6 0.9 2.1 1 0 0 1 1 1 0 Melittin MFS_1 PF07690.16 AAAP01002818.1_2 - 0.0041 16.1 0.7 0.0041 16.1 0.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.21 AAAP01002818.1_2 - 0.021 14.7 0.7 0.029 14.3 0.7 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif YqjK PF13997.6 AAAP01002818.1_2 - 0.059 13.6 0.0 0.069 13.4 0.0 1.1 1 0 0 1 1 1 0 YqjK-like protein FAA_hydrolase PF01557.18 AAAP01002818.1_3 - 1.5e-44 152.3 0.0 2.4e-44 151.6 0.0 1.3 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AAAP01002818.1_3 - 3.7e-10 40.5 1.8 9.5e-10 39.2 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2437) ApbA PF02558.16 AAAP01002818.1_4 - 1.4e-27 96.2 0.9 3.1e-27 95.1 0.9 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AAAP01002818.1_4 - 3e-07 30.9 1.4 3e-07 30.9 1.4 1.7 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 AAAP01002818.1_4 - 9.1e-06 25.7 0.2 1.5e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 AAAP01002818.1_4 - 5.6e-05 22.8 0.3 8.9e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 AAAP01002818.1_4 - 0.00023 21.4 0.6 0.00035 20.8 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 AAAP01002818.1_4 - 0.0046 17.5 0.9 0.0089 16.6 0.9 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAAP01002818.1_4 - 0.007 15.6 1.0 0.009 15.3 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AAAP01002818.1_4 - 0.011 16.0 0.9 0.02 15.1 0.9 1.6 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 AAAP01002818.1_4 - 0.011 15.6 1.6 0.016 15.1 1.6 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AAAP01002818.1_4 - 0.042 13.7 1.4 0.069 13.0 1.4 1.4 1 1 0 1 1 1 0 Rossmann-like domain FAD_binding_3 PF01494.19 AAAP01002818.1_4 - 0.049 12.9 0.7 0.063 12.5 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 AAAP01002818.1_4 - 0.091 13.0 0.8 0.37 11.1 0.2 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Beta-lactamase PF00144.24 AAAP01002819.1_2 - 1.4e-32 113.2 0.3 2.4e-32 112.5 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase LVIVD PF08309.11 AAAP01002819.1_2 - 0.24 10.7 0.8 1 8.7 0.7 2.1 2 0 0 2 2 2 0 LVIVD repeat Response_reg PF00072.24 AAAP01002820.1_1 - 2.7e-15 56.5 0.0 4.2e-15 55.9 0.0 1.3 1 1 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAAP01002820.1_1 - 0.0021 18.4 0.0 0.0025 18.1 0.0 1.0 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ CBP_BcsS PF17036.5 AAAP01002820.1_2 - 8e-52 175.0 3.0 8e-52 175.0 3.0 2.0 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsS EF_TS PF00889.19 AAAP01002821.1_1 - 1.8e-62 210.7 0.1 2.4e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.31 AAAP01002821.1_1 - 0.0099 15.8 0.4 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain HOIP-UBA PF16678.5 AAAP01002821.1_1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 HOIP UBA domain pair HHH_5 PF14520.6 AAAP01002821.1_2 - 3.6e-06 27.5 0.0 0.0073 16.9 0.0 1.8 1 1 1 2 2 2 2 Helix-hairpin-helix domain IMS_HHH PF11798.8 AAAP01002821.1_2 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif Cdd1 PF11731.8 AAAP01002821.1_2 - 0.16 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity locus FolB PF02152.18 AAAP01002822.1_1 - 5.1e-31 107.5 0.0 5.7e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase GPW_gp25 PF04965.14 AAAP01002822.1_1 - 0.019 14.7 0.1 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 Gene 25-like lysozyme Pterin_bind PF00809.22 AAAP01002822.1_2 - 2.1e-85 286.3 0.0 2.5e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme PEP_mutase PF13714.6 AAAP01002822.1_2 - 0.0083 15.6 0.1 0.12 11.8 0.3 2.8 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3592 PF12158.8 AAAP01002822.1_4 - 0.15 12.1 0.0 0.16 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) ACR_tran PF00873.19 AAAP01002823.1_1 - 4.4e-95 319.3 0.9 5.4e-95 319.0 0.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Filo_VP35 PF02097.15 AAAP01002823.1_1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 SurA_N_3 PF13624.6 AAAP01002824.1_2 - 2.6e-43 147.6 2.0 3.3e-43 147.3 2.0 1.1 1 0 0 1 1 1 1 SurA N-terminal domain SurA_N_2 PF13623.6 AAAP01002824.1_2 - 2.8e-32 111.6 0.4 3.9e-32 111.1 0.4 1.2 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_2 PF13145.6 AAAP01002824.1_2 - 7.9e-07 29.9 2.8 6.2e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 AAAP01002824.1_2 - 7.7e-06 26.0 0.6 1.1e-05 25.4 0.6 1.3 1 0 0 1 1 1 1 SurA N-terminal domain DUF2427 PF10348.9 AAAP01002825.1_1 - 0.42 10.4 0.1 0.42 10.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Acyl_transf_3 PF01757.22 AAAP01002825.1_1 - 0.55 9.2 15.0 3.5 6.6 15.0 1.9 1 1 0 1 1 1 0 Acyltransferase family Fer4_13 PF13370.6 AAAP01002825.1_2 - 3.5e-09 37.1 0.1 4.4e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAAP01002825.1_2 - 1.4e-08 35.4 0.5 2.8e-08 34.4 0.5 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 AAAP01002825.1_2 - 3.5e-05 23.8 0.0 3.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Pyr_redox_2 PF07992.14 AAAP01002825.1_3 - 1.8e-06 27.4 0.0 2.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01002825.1_3 - 0.064 13.5 0.5 0.13 12.5 0.5 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HD PF01966.22 AAAP01002826.1_1 - 7.4e-09 35.9 0.0 2.4e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 HD domain DUF3268 PF11672.8 AAAP01002827.1_1 - 0.00063 20.1 0.1 0.0045 17.3 0.1 2.1 1 1 1 2 2 2 1 zinc-finger-containing domain TPR_2 PF07719.17 AAAP01002828.1_1 - 1.7e-28 96.4 0.4 2.1e-06 27.4 0.0 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01002828.1_1 - 1.3e-21 75.5 0.0 0.00011 21.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01002828.1_1 - 4.5e-21 74.3 0.0 7.6e-09 35.1 0.0 5.5 4 1 1 5 5 5 4 TPR repeat TPR_14 PF13428.6 AAAP01002828.1_1 - 1.5e-18 65.9 6.5 1.9e-05 25.1 0.0 6.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01002828.1_1 - 5.9e-18 64.9 4.1 5.2e-05 23.4 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01002828.1_1 - 2e-17 63.4 3.3 0.00015 22.2 0.0 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01002828.1_1 - 5.6e-16 58.9 6.6 4e-05 24.2 0.0 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01002828.1_1 - 2.1e-15 55.5 0.0 0.00019 21.2 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01002828.1_1 - 1.8e-14 53.0 5.7 0.00022 21.0 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01002828.1_1 - 1.3e-13 50.0 0.0 0.014 15.6 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01002828.1_1 - 6.6e-12 45.3 3.5 0.037 14.7 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01002828.1_1 - 2.2e-11 43.7 2.6 0.0044 17.1 0.0 4.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01002828.1_1 - 6.4e-10 38.7 0.5 1.3 9.6 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01002828.1_1 - 1.1e-07 31.4 2.0 1.3e-05 24.5 0.3 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01002828.1_1 - 4.2e-05 23.8 10.9 0.016 15.8 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 AAAP01002828.1_1 - 4.4e-05 22.8 0.0 0.18 11.3 0.0 3.2 3 0 0 3 3 3 2 SHNi-TPR ANAPC3 PF12895.7 AAAP01002828.1_1 - 7.2e-05 22.9 0.1 4 7.7 0.1 3.7 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AAAP01002828.1_1 - 7.3e-05 23.2 1.0 0.0029 18.1 0.1 3.0 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 AAAP01002828.1_1 - 0.0021 17.5 0.0 0.025 14.0 0.0 2.3 1 1 1 2 2 2 1 MalT-like TPR region Fis1_TPR_C PF14853.6 AAAP01002828.1_1 - 0.0023 18.0 0.0 9.2 6.4 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 AAAP01002828.1_1 - 0.015 15.6 0.2 2.9 8.3 0.4 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 AAAP01002828.1_1 - 0.038 12.9 0.2 0.74 8.7 0.0 2.5 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 MIT PF04212.18 AAAP01002828.1_1 - 0.12 12.4 0.0 3.9 7.6 0.0 3.1 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 AAAP01002828.1_1 - 0.14 12.2 0.1 11 6.1 0.0 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Response_reg PF00072.24 AAAP01002829.1_1 - 9.9e-16 57.9 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain adh_short PF00106.25 AAAP01002829.1_2 - 1.9e-42 145.0 0.0 2.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01002829.1_2 - 1e-40 139.8 0.0 1.3e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 AAAP01002829.1_2 - 0.0055 16.2 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAAP01002829.1_2 - 0.18 11.1 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HhH-GPD PF00730.25 AAAP01002830.1_1 - 1.6e-06 28.5 0.0 2.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 AAAP01002830.1_1 - 0.00012 22.3 3.2 0.0003 21.0 3.2 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.23 AAAP01002830.1_1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAAP01002830.1_1 - 0.19 12.4 0.0 0.48 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain UPF0060 PF02694.15 AAAP01002830.1_3 - 5.9e-35 119.7 7.7 7e-35 119.5 7.7 1.1 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Alpha-amylase_C PF02806.18 AAAP01002830.1_4 - 1e-15 58.0 0.0 1.1e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain MINDY_DUB PF04424.13 AAAP01002831.1_2 - 0.036 14.1 0.0 0.036 14.1 0.0 1.0 1 0 0 1 1 1 0 MINDY deubiquitinase 3HCDH_N PF02737.18 AAAP01002832.1_2 - 5.2e-58 195.9 0.0 6.7e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAAP01002832.1_2 - 2.7e-34 117.7 0.0 5.6e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain F420_oxidored PF03807.17 AAAP01002832.1_2 - 1.8e-05 25.2 0.1 3.9e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAAP01002832.1_2 - 4.2e-05 23.8 0.0 0.00011 22.4 0.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01002832.1_2 - 0.00011 21.7 0.1 0.00024 20.5 0.1 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AAAP01002832.1_2 - 0.0013 18.3 0.0 0.0038 16.9 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 AAAP01002832.1_2 - 0.013 14.9 0.0 0.026 14.0 0.0 1.4 2 0 0 2 2 2 0 short chain dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAAP01002832.1_2 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 AAAP01002832.1_2 - 0.015 15.5 0.1 0.029 14.6 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAAP01002832.1_2 - 0.072 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AAAP01002832.1_2 - 0.26 10.6 0.5 0.48 9.7 0.5 1.4 1 0 0 1 1 1 0 ThiF family ETF_alpha PF00766.19 AAAP01002832.1_3 - 8.3e-36 121.9 0.2 1.6e-35 121.0 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Acyl-CoA_dh_1 PF00441.24 AAAP01002833.1_1 - 2.5e-25 89.5 0.5 2.6e-25 89.4 0.5 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01002833.1_1 - 4.1e-12 46.5 0.3 4.6e-12 46.4 0.3 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mtd_N PF18454.1 AAAP01002833.1_1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain DNA_mis_repair PF01119.19 AAAP01002833.1_2 - 4.6e-14 52.1 0.0 7.1e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AAAP01002833.1_2 - 1.9e-11 43.9 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01002833.1_2 - 3.5e-07 30.7 0.1 6.6e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_20 PF12840.7 AAAP01002833.1_2 - 0.11 12.5 0.7 0.51 10.4 0.2 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain ArabFuran-catal PF09206.11 AAAP01002833.1_2 - 0.18 11.1 0.5 0.26 10.6 0.5 1.2 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic PAS_4 PF08448.10 AAAP01002834.1_1 - 2.6e-10 40.5 0.6 1.3e-05 25.4 0.3 2.6 2 1 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01002834.1_1 - 3.7e-07 30.1 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01002834.1_1 - 1.9e-06 27.8 0.0 0.041 13.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 AAAP01002834.1_1 - 0.0013 18.9 0.0 0.53 10.6 0.0 2.6 2 1 0 2 2 2 2 PAS domain RecO_C PF02565.15 AAAP01002834.1_1 - 0.007 16.2 0.4 0.024 14.4 0.0 2.1 3 0 0 3 3 3 1 Recombination protein O C terminal DUF3995 PF13160.6 AAAP01002834.1_1 - 0.016 15.6 4.3 0.031 14.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Bac_export_2 PF01312.19 AAAP01002834.1_2 - 3.6e-76 256.5 2.1 4.2e-76 256.3 2.1 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family DUF2399 PF09664.10 AAAP01002834.1_2 - 0.028 14.3 6.4 0.69 9.8 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function C-terminus (DUF2399) Amino_oxidase PF01593.24 AAAP01002835.1_1 - 4.3e-21 75.7 1.5 1.8e-20 73.7 1.5 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 AAAP01002835.1_1 - 1.1e-06 28.5 3.5 1.8e-06 27.8 3.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01002835.1_1 - 0.0019 17.4 0.3 0.0032 16.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 AAAP01002835.1_1 - 0.047 12.5 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase SepZ PF06066.11 AAAP01002835.1_1 - 0.28 11.4 3.1 2.7 8.3 3.1 2.3 1 1 1 2 2 2 0 SepZ 5_nucleotid_C PF02872.18 AAAP01002836.1_1 - 7.7e-33 113.9 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain UDG PF03167.19 AAAP01002836.1_2 - 2.1e-21 76.5 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PAP2 PF01569.21 AAAP01002837.1_1 - 7.7e-14 51.6 0.3 1.5e-13 50.7 0.1 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AAAP01002837.1_1 - 0.1 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 PAP2 superfamily Glycos_transf_1 PF00534.20 AAAP01002838.1_1 - 6e-22 78.0 0.0 9.6e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01002838.1_1 - 2.3e-12 47.5 0.0 4.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01002838.1_1 - 0.00035 20.9 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 sCache_3_3 PF17202.4 AAAP01002838.1_1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 GDE_N_bis PF14742.6 AAAP01002838.1_2 - 5.4e-52 176.2 0.1 7.1e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain of (some) glycogen debranching enzymes Peripla_BP_6 PF13458.6 AAAP01002839.1_1 - 4.4e-30 105.5 14.8 5.2e-30 105.3 14.8 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01002839.1_1 - 5.2e-07 29.0 0.0 8.7e-07 28.3 0.0 1.3 1 1 0 1 1 1 1 Periplasmic binding protein domain ABC_tran PF00005.27 AAAP01002839.1_2 - 3.4e-13 50.3 0.0 4.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01002839.1_2 - 8.2e-08 32.0 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAAP01002839.1_2 - 0.0019 18.0 0.0 0.0022 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system EFG_C PF00679.24 AAAP01002840.1_1 - 1.3e-21 76.4 0.0 2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus MCPsignal PF00015.21 AAAP01002840.1_2 - 2.2e-28 99.2 28.0 1.8e-26 93.0 27.9 3.3 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01002840.1_2 - 0.0027 17.9 9.5 0.6 10.4 0.2 3.7 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF948) DEAD PF00270.29 AAAP01002840.1_2 - 0.068 12.9 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF1664 PF07889.12 AAAP01002840.1_2 - 0.18 11.8 2.5 19 5.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1168 PF06658.12 AAAP01002840.1_2 - 0.32 10.8 1.0 1.4 8.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) WXG100 PF06013.12 AAAP01002840.1_2 - 0.35 11.1 11.2 0.98 9.7 1.5 3.5 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Acyl-ACP_TE PF01643.17 AAAP01002841.1_2 - 0.025 13.9 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Acyl-ACP thioesterase HD_assoc PF13286.6 AAAP01002841.1_3 - 2.2e-23 82.6 0.1 5.4e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Phosphohydrolase-associated domain ACR_tran PF00873.19 AAAP01002842.1_1 - 2.5e-122 409.5 0.1 3e-122 409.3 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAAP01002842.1_1 - 0.0036 16.7 7.8 0.008 15.6 7.8 1.5 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 AAAP01002842.1_1 - 0.43 9.5 14.6 0.96 8.3 14.6 1.6 1 0 0 1 1 1 0 MMPL family FlgI PF02119.16 AAAP01002843.1_1 - 5.1e-08 32.2 0.1 5.4e-08 32.2 0.1 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein MgtE_N PF03448.17 AAAP01002843.1_2 - 1.4e-06 28.8 0.8 1.4e-06 28.8 0.8 2.0 2 0 0 2 2 2 1 MgtE intracellular N domain Ycf54 PF10674.9 AAAP01002843.1_2 - 0.0043 17.3 0.6 0.0073 16.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2488) FliG_M PF14841.6 AAAP01002843.1_2 - 0.0074 16.5 3.6 0.053 13.8 1.8 2.4 1 1 1 2 2 2 1 FliG middle domain Dehydratase_SU PF02287.15 AAAP01002843.1_2 - 0.066 13.3 4.2 0.086 12.9 3.2 1.7 1 1 1 2 2 2 0 Dehydratase small subunit DUF4635 PF15466.6 AAAP01002843.1_2 - 0.076 12.5 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DUF1043 PF06295.12 AAAP01002843.1_2 - 0.1 12.6 0.5 0.17 11.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) FlgH PF02107.16 AAAP01002843.1_4 - 3.6e-55 186.1 0.6 4e-55 186.0 0.6 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein Arm-DNA-bind_3 PF13356.6 AAAP01002844.1_1 - 0.01 16.2 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain RadC PF04002.15 AAAP01002844.1_2 - 4.8e-22 78.2 0.0 7.9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 RadC-like JAB domain HHH_5 PF14520.6 AAAP01002844.1_2 - 0.0027 18.3 0.1 0.0057 17.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 AAAP01002844.1_2 - 0.035 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M24 PF00557.24 AAAP01002844.1_3 - 3e-12 46.7 0.0 3.5e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF459 PF04311.13 AAAP01002845.1_1 - 1.3e-35 123.0 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF459) Lipase_GDSL_2 PF13472.6 AAAP01002845.1_1 - 8.2e-09 36.1 0.3 1.4e-08 35.4 0.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAAP01002845.1_1 - 0.00032 20.7 0.0 0.00046 20.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase baeRF_family8 PF18851.1 AAAP01002845.1_1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 PAS_4 PF08448.10 AAAP01002846.1_1 - 8.1e-36 122.6 5.5 1.7e-17 63.7 0.4 3.2 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAAP01002846.1_1 - 1.2e-17 64.0 0.0 2.4e-08 34.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01002846.1_1 - 1.7e-16 60.4 0.0 3e-06 27.4 0.0 3.3 3 0 0 3 3 3 2 PAS domain GGDEF PF00990.21 AAAP01002846.1_1 - 5.2e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_8 PF13188.7 AAAP01002846.1_1 - 1.3e-07 31.4 0.0 0.00013 21.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AAAP01002846.1_1 - 0.00093 19.4 0.1 0.037 14.3 0.0 2.9 2 1 0 2 2 2 1 PAS fold PAS_7 PF12860.7 AAAP01002846.1_1 - 0.0021 18.2 0.1 1.1 9.4 0.0 3.6 2 2 1 3 3 3 1 PAS fold PAS_10 PF13596.6 AAAP01002846.1_1 - 0.0025 18.4 0.0 2.6 8.7 0.0 2.3 2 0 0 2 2 2 2 PAS domain ALC PF17527.2 AAAP01002846.1_1 - 0.052 13.2 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Phage ALC protein TrkA_N PF02254.18 AAAP01002847.1_1 - 8.6e-22 77.6 0.1 1.6e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Na_H_Exchanger PF00999.21 AAAP01002847.1_1 - 8e-10 38.1 7.1 1e-09 37.7 7.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NAD_binding_7 PF13241.6 AAAP01002847.1_1 - 1.9e-07 31.4 0.0 3.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 AAAP01002847.1_1 - 0.00024 20.4 0.1 0.00026 20.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 AAAP01002847.1_1 - 0.0023 18.2 0.3 0.0043 17.3 0.3 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 AAAP01002847.1_1 - 0.0026 17.2 0.5 0.0067 15.8 0.1 1.8 2 0 0 2 2 2 1 ThiF family 3HCDH_N PF02737.18 AAAP01002847.1_1 - 0.0045 16.9 0.1 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01002847.1_1 - 0.0071 15.9 0.2 0.014 15.0 0.2 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AAAP01002847.1_1 - 0.0091 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAAP01002847.1_1 - 0.011 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AAAP01002847.1_1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAAP01002847.1_1 - 0.03 14.9 0.1 0.067 13.8 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AAAP01002847.1_1 - 0.048 13.3 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PGM_PMM_IV PF00408.20 AAAP01002847.1_1 - 0.052 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain XdhC_C PF13478.6 AAAP01002847.1_1 - 0.087 13.3 0.1 0.24 11.9 0.1 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain IlvN PF07991.12 AAAP01002847.1_1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MatE PF01554.18 AAAP01002847.1_2 - 5.6e-17 61.9 22.8 1e-08 35.0 3.4 3.2 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 AAAP01002847.1_2 - 4.6e-05 23.5 17.8 4.6e-05 23.5 17.8 3.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Biotin_lipoyl_2 PF13533.6 AAAP01002848.1_1 - 1.6e-07 31.0 0.3 0.0028 17.4 0.0 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AAAP01002848.1_1 - 2.7e-07 30.0 0.9 0.0076 15.5 0.0 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01002848.1_1 - 0.00064 20.4 0.2 0.03 15.0 0.1 2.7 2 1 1 3 3 3 1 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAAP01002848.1_1 - 0.00097 18.9 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Atg14 PF10186.9 AAAP01002848.1_1 - 0.51 9.4 6.2 0.61 9.1 6.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OEP PF02321.18 AAAP01002848.1_1 - 2 8.2 16.6 0.091 12.6 11.2 1.5 2 0 0 2 2 2 0 Outer membrane efflux protein Proton_antipo_M PF00361.20 AAAP01002849.1_1 - 1.9e-35 122.5 9.7 2.7e-35 122.0 9.7 1.1 1 0 0 1 1 1 1 Proton-conducting membrane transporter CcmF_C PF16327.5 AAAP01002849.1_1 - 0.09 12.0 7.1 0.02 14.2 3.7 1.5 1 1 1 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal ABC_membrane PF00664.23 AAAP01002849.1_2 - 0.056 13.1 6.1 9.6 5.8 0.3 3.1 3 0 0 3 3 3 0 ABC transporter transmembrane region COX1 PF00115.20 AAAP01002850.1_1 - 2.4e-154 514.3 72.2 2.4e-154 514.3 72.2 1.2 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I E1-E2_ATPase PF00122.20 AAAP01002850.1_1 - 0.45 10.0 4.7 2.1 7.9 4.7 2.1 1 0 0 1 1 1 0 E1-E2 ATPase LptD PF04453.14 AAAP01002851.1_2 - 1.2e-54 186.1 3.4 1.5e-54 185.8 3.4 1.1 1 0 0 1 1 1 1 LPS transport system D AAA PF00004.29 AAAP01002852.1_1 - 1.2e-20 74.2 0.0 3.6e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 AAAP01002852.1_1 - 4e-10 39.9 1.8 1.8e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 AAAP01002852.1_1 - 3e-09 37.0 0.0 8e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 AAAP01002852.1_1 - 1.8e-05 23.8 0.1 4.2e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 AAAP01002852.1_1 - 0.00041 20.5 0.3 0.0018 18.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 AAAP01002852.1_1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAAP01002852.1_1 - 0.0011 19.2 1.8 0.01 16.1 0.2 2.6 2 1 0 2 2 1 1 AAA domain ABC_tran PF00005.27 AAAP01002852.1_1 - 0.0017 18.9 2.9 0.74 10.3 0.2 3.2 1 1 1 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 AAAP01002852.1_1 - 0.0023 17.7 0.8 0.0081 15.9 0.0 2.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.6 AAAP01002852.1_1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01002852.1_1 - 0.0024 18.3 0.1 0.0024 18.3 0.1 2.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 AAAP01002852.1_1 - 0.0027 18.2 2.1 0.0083 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AAAP01002852.1_1 - 0.0031 17.4 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ECH_2 PF16113.5 AAAP01002852.1_1 - 0.0031 17.0 2.3 0.0047 16.5 2.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AAA_23 PF13476.6 AAAP01002852.1_1 - 0.012 16.1 6.9 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAAP01002852.1_1 - 0.016 15.4 0.8 0.039 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01002852.1_1 - 0.018 14.9 0.5 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 AAAP01002852.1_1 - 0.03 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 AAAP01002852.1_1 - 0.033 14.3 1.2 0.78 9.8 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 AAAP01002852.1_1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AAAP01002852.1_1 - 0.086 12.8 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 AAAP01002852.1_1 - 0.098 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 AAAP01002852.1_1 - 0.099 12.8 6.0 0.2 11.7 0.1 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 AAAP01002852.1_1 - 0.12 12.7 0.2 0.34 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAAP01002852.1_1 - 0.2 11.6 4.4 2.6 7.9 0.2 2.9 2 1 1 3 3 3 0 NTPase ATPase_2 PF01637.18 AAAP01002852.1_1 - 1.2 9.0 6.2 1.5 8.6 0.0 3.1 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea DUF5446 PF17522.2 AAAP01002852.1_1 - 4.2 7.6 7.0 2.8 8.2 4.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5446) GSDH PF07995.11 AAAP01002853.1_1 - 1.7e-11 44.0 0.3 9.3e-11 41.6 0.3 2.0 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 AAAP01002853.1_1 - 0.0013 18.7 0.3 0.027 14.5 0.2 2.5 2 0 0 2 2 2 1 NHL repeat SGL PF08450.12 AAAP01002853.1_1 - 0.071 12.7 0.1 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region YkuD PF03734.14 AAAP01002853.1_2 - 2.3e-20 73.5 0.0 3.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF179 PF02622.15 AAAP01002854.1_1 - 7.1e-13 48.8 0.0 7.8e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Peptidase_Mx PF15887.5 AAAP01002854.1_2 - 4.8e-110 366.5 0.1 5.6e-110 366.3 0.1 1.0 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase zinc-ribbon_6 PF10005.9 AAAP01002854.1_2 - 8.9e-11 42.3 0.8 1.6e-10 41.5 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_Mx1 PF15890.5 AAAP01002854.1_2 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase HisG PF01634.18 AAAP01002855.1_1 - 2.1e-40 138.3 0.0 2.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 AAAP01002855.1_1 - 8.6e-25 86.7 1.5 9.3e-25 86.6 0.1 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain bPH_6 PF10756.9 AAAP01002855.1_2 - 7.7e-15 54.7 3.8 1.5e-14 53.8 3.8 1.5 1 0 0 1 1 1 1 Bacterial PH domain Citrate_synt PF00285.21 AAAP01002856.1_1 - 2.3e-129 431.6 0.0 2.6e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Proton_antipo_M PF00361.20 AAAP01002857.1_1 - 5.4e-32 111.2 8.0 5.4e-32 111.2 8.0 1.9 1 1 1 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAAP01002857.1_1 - 7.1e-12 45.2 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 AAAP01002857.1_2 - 2.2e-19 69.0 7.4 2.7e-19 68.8 7.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pox_A14 PF05767.12 AAAP01002857.1_2 - 0.083 13.0 1.4 0.1 12.7 1.1 1.3 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 CbiQ PF02361.16 AAAP01002857.1_2 - 0.24 11.0 7.9 0.28 10.8 7.9 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF2371 PF10177.9 AAAP01002857.1_2 - 1.6 8.9 7.5 5.6 7.1 1.2 2.5 1 1 2 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF4418 PF14387.6 AAAP01002857.1_2 - 1.6 8.9 7.0 2.9 8.1 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Phage_holin_3_6 PF07332.11 AAAP01002857.1_2 - 9.5 6.3 17.7 5.8e+02 0.6 17.5 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TilS_C PF11734.8 AAAP01002858.1_1 - 0.015 14.7 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 TilS substrate C-terminal domain DUF4679 PF15728.5 AAAP01002858.1_2 - 0.015 14.4 0.1 0.025 13.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4679) RES PF08808.11 AAAP01002858.1_3 - 5.9e-08 32.8 2.0 8.7e-08 32.2 2.0 1.2 1 0 0 1 1 1 1 RES domain HATPase_c PF02518.26 AAAP01002859.1_1 - 8e-20 71.4 0.0 1.6e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01002859.1_1 - 3.1e-16 59.5 0.0 7.9e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain HPTransfase PF10090.9 AAAP01002859.1_1 - 0.00011 21.9 0.1 0.0027 17.5 0.0 2.4 2 1 0 2 2 2 1 Histidine phosphotransferase C-terminal domain HATPase_c_2 PF13581.6 AAAP01002859.1_1 - 0.0049 16.8 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01002859.1_1 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_tranf_2_3 PF13641.6 AAAP01002859.1_1 - 0.1 12.4 0.0 18 5.1 0.0 2.8 1 1 1 3 3 3 0 Glycosyltransferase like family 2 Metallothio_Pro PF02069.16 AAAP01002859.1_3 - 1.2e-21 76.7 20.5 1.3e-21 76.5 20.5 1.0 1 0 0 1 1 1 1 Prokaryotic metallothionein CnrY PF17524.2 AAAP01002860.1_2 - 0.015 15.5 0.2 0.048 13.9 0.2 1.9 1 0 0 1 1 1 0 Anti-sigma factor CnrY Glycos_transf_1 PF00534.20 AAAP01002861.1_1 - 7.7e-15 54.8 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01002861.1_1 - 8.1e-14 52.2 0.1 1.5e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_3 PF12000.8 AAAP01002861.1_1 - 4.2e-08 33.1 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 4 group Glyco_trans_1_2 PF13524.6 AAAP01002861.1_1 - 6.9e-06 26.4 0.2 1.7e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01002861.1_1 - 0.024 14.7 2.6 0.034 14.1 0.0 2.5 4 0 0 4 4 4 0 Glycosyltransferase Family 4 Methyltransf_33 PF10017.9 AAAP01002861.1_2 - 4.8e-84 282.1 0.0 5.3e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 AAAP01002861.1_2 - 0.0038 17.9 0.0 0.018 15.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002861.1_2 - 0.0053 17.5 0.0 0.015 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002861.1_2 - 0.017 14.9 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain BPD_transp_1 PF00528.22 AAAP01002862.1_1 - 1.2e-22 80.5 5.7 1.2e-22 80.5 5.7 1.4 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PilO PF04350.13 AAAP01002862.1_2 - 0.089 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO Ald_Xan_dh_C2 PF02738.18 AAAP01002863.1_1 - 1.3e-37 129.6 2.1 9.4e-36 123.4 0.8 2.1 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01002863.1_1 - 0.00027 21.3 0.8 0.073 13.4 0.0 3.2 2 1 1 3 3 3 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain GcpE PF04551.14 AAAP01002864.1_1 - 6.8e-128 426.6 0.0 7.8e-128 426.5 0.0 1.0 1 0 0 1 1 1 1 GcpE protein zf-RING_7 PF02591.15 AAAP01002864.1_1 - 0.065 13.4 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain Peptidase_M50 PF02163.22 AAAP01002864.1_2 - 1.7e-12 47.1 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M50 UvdE PF03851.14 AAAP01002865.1_1 - 4.8e-30 104.7 0.0 6.5e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 AAAP01002865.1_1 - 0.044 13.2 0.1 1.2 8.5 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel CT_A_B PF02626.15 AAAP01002865.1_2 - 6.6e-87 291.5 0.3 7.9e-87 291.2 0.3 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 AAAP01002865.1_3 - 1.3e-65 220.9 0.1 1.7e-65 220.6 0.1 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D ChaC PF04752.12 AAAP01002866.1_1 - 1e-46 159.2 0.0 1.3e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 AAAP01002866.1_1 - 0.0019 18.8 0.0 0.0035 17.9 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SLT_2 PF13406.6 AAAP01002866.1_2 - 2e-08 33.8 0.1 0.00017 20.9 0.1 2.0 1 1 1 2 2 2 2 Transglycosylase SLT domain ANT PF03374.14 AAAP01002867.1_1 - 4.1e-13 49.6 0.0 4.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Phage antirepressor protein KilAC domain Thioesterase PF00975.20 AAAP01002868.1_2 - 2.3e-05 24.7 0.0 3.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain LCAT PF02450.15 AAAP01002868.1_2 - 4.5e-05 22.8 0.0 6.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 AAAP01002868.1_2 - 0.00016 21.0 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FGase PF05013.12 AAAP01002868.1_2 - 0.016 15.4 0.0 0.027 14.7 0.0 1.5 1 1 0 1 1 1 0 N-formylglutamate amidohydrolase DUF900 PF05990.12 AAAP01002868.1_2 - 0.031 13.8 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glyco_trans_4_4 PF13579.6 AAAP01002868.1_2 - 0.043 14.2 4.5 0.5 10.8 2.4 2.3 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Abhydrolase_6 PF12697.7 AAAP01002868.1_2 - 0.044 14.4 8.8 0.073 13.7 8.2 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family TrbL PF04610.14 AAAP01002869.1_1 - 1.5e-53 181.7 20.8 1.9e-53 181.4 20.8 1.1 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Glyco_transf_7C PF02709.14 AAAP01002869.1_1 - 0.052 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase ACC_epsilon PF13822.6 AAAP01002869.1_3 - 3.8 8.2 10.5 0.38 11.5 4.6 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit MutS_V PF00488.21 AAAP01002870.1_2 - 4.6e-84 281.1 0.0 8.5e-84 280.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 AAAP01002870.1_2 - 1.2e-34 120.3 1.2 2.3e-34 119.3 1.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 AAAP01002870.1_2 - 2.7e-18 66.1 0.0 4.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 AAAP01002870.1_2 - 0.037 13.8 0.2 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ACR_tran PF00873.19 AAAP01002871.1_1 - 1.7e-171 572.3 1.1 2e-171 572.0 1.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAAP01002871.1_1 - 0.00049 19.5 9.3 0.00084 18.8 9.3 1.3 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 AAAP01002871.1_1 - 0.0006 18.8 14.7 0.002 17.1 12.6 2.2 2 0 0 2 2 2 1 MMPL family Polysacc_deac_1 PF01522.21 AAAP01002872.1_1 - 5.2e-22 78.1 0.0 8.8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase TUDOR_5 PF18359.1 AAAP01002872.1_1 - 0.076 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Acetyltransf_6 PF13480.7 AAAP01002872.1_2 - 3.7e-13 49.8 4.0 3.7e-13 49.8 4.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 AAAP01002872.1_2 - 0.00064 18.7 0.0 0.0025 16.8 0.0 1.8 2 0 0 2 2 2 1 FemAB family Acetyltransf_1 PF00583.25 AAAP01002872.1_2 - 0.013 15.7 0.2 0.03 14.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Polysacc_synt_3 PF13440.6 AAAP01002872.1_3 - 0.036 13.3 5.6 0.051 12.8 5.3 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Gaa1 PF04114.14 AAAP01002872.1_3 - 0.095 11.7 2.6 0.11 11.5 2.6 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF3429 PF11911.8 AAAP01002873.1_3 - 1.9e-33 115.8 16.5 2.1e-33 115.6 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Voltage_CLC PF00654.20 AAAP01002873.1_4 - 2e-06 27.3 0.9 0.0021 17.4 0.0 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel ABC_tran PF00005.27 AAAP01002874.1_2 - 3.5e-32 111.8 0.0 5e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002874.1_2 - 1.2e-06 28.5 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01002874.1_2 - 3.3e-06 27.6 0.4 7.6e-06 26.4 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain SMC_N PF02463.19 AAAP01002874.1_2 - 7.7e-06 25.5 0.1 0.083 12.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01002874.1_2 - 6.6e-05 22.9 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAAP01002874.1_2 - 0.00018 21.2 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAAP01002874.1_2 - 0.00038 20.9 0.0 0.0031 17.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AAAP01002874.1_2 - 0.0013 19.2 0.2 0.0024 18.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01002874.1_2 - 0.0024 18.1 0.1 0.0065 16.7 0.1 1.8 1 1 1 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAAP01002874.1_2 - 0.0027 16.6 0.1 0.47 9.2 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 AAAP01002874.1_2 - 0.0037 17.3 0.1 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 AAAP01002874.1_2 - 0.0054 16.5 0.2 0.057 13.1 0.1 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AAAP01002874.1_2 - 0.017 15.4 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01002874.1_2 - 0.019 14.5 0.1 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAAP01002874.1_2 - 0.023 14.6 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AAAP01002874.1_2 - 0.024 14.6 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 AAAP01002874.1_2 - 0.026 14.3 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 AAAP01002874.1_2 - 0.038 14.0 0.1 0.08 13.0 0.1 1.5 1 0 0 1 1 1 0 Dynamin family ATPase_2 PF01637.18 AAAP01002874.1_2 - 0.039 13.9 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AAAP01002874.1_2 - 0.071 13.7 0.1 0.33 11.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAAP01002874.1_2 - 0.072 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01002874.1_2 - 0.079 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 AAAP01002874.1_2 - 0.09 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 AAAP01002874.1_2 - 0.098 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 AAAP01002874.1_2 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B CTP_transf_3 PF02348.19 AAAP01002875.1_1 - 3.7e-37 128.4 0.0 6.1e-37 127.7 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01002875.1_1 - 1.7e-11 44.7 2.9 2.3e-11 44.3 2.9 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 AAAP01002875.1_1 - 1.7e-05 24.6 0.1 3.4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_tranf_2_3 PF13641.6 AAAP01002875.1_1 - 0.00061 19.7 0.2 0.0012 18.8 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 PDT PF00800.18 AAAP01002875.1_2 - 3.3e-50 170.5 0.0 3.6e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydratase DDE_Tnp_1_2 PF13586.6 AAAP01002876.1_1 - 8e-18 64.6 0.3 9.7e-18 64.3 0.3 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01002876.1_1 - 3.2e-13 49.8 0.1 8.1e-09 35.4 0.0 2.0 2 0 0 2 2 2 2 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01002876.1_1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Glyco_trans_4_4 PF13579.6 AAAP01002877.1_1 - 4.9e-13 49.8 25.9 6.1e-12 46.3 16.5 2.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01002877.1_1 - 6.9e-12 45.7 3.8 2.5e-10 40.6 1.0 2.9 2 1 0 3 3 3 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01002877.1_1 - 1e-09 38.1 0.0 2.2e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01002877.1_1 - 8.5e-09 35.9 0.0 3e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 AAAP01002877.1_1 - 0.0006 19.6 0.2 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Ni_hydr_CYTB PF01292.20 AAAP01002878.1_1 - 1.4e-15 57.3 7.8 1.8e-15 57.0 7.8 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AAAP01002878.1_1 - 0.00083 19.8 9.2 0.00083 19.8 9.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4405) Cytochrom_B561 PF03188.16 AAAP01002878.1_1 - 0.0043 17.2 1.7 0.0066 16.6 1.7 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF1180 PF06679.12 AAAP01002878.1_3 - 1.3 9.4 20.6 0.32 11.4 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) MSP1_C PF07462.11 AAAP01002878.1_3 - 4.6 5.8 4.7 6.1 5.4 4.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Aminotran_5 PF00266.19 AAAP01002879.1_1 - 6e-31 107.7 0.0 7.1e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01002879.1_1 - 0.0018 16.9 0.0 0.0028 16.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FCD PF07729.12 AAAP01002879.1_2 - 6.7e-23 81.5 10.8 9.8e-23 80.9 10.8 1.2 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01002879.1_2 - 0.013 15.1 0.2 0.071 12.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family FAD_binding_2 PF00890.24 AAAP01002879.1_2 - 0.041 13.0 0.1 0.05 12.7 0.1 1.0 1 0 0 1 1 1 0 FAD binding domain Acetyltransf_1 PF00583.25 AAAP01002880.1_2 - 1.8e-08 34.6 0.0 2.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01002880.1_2 - 1e-05 25.8 0.0 1.5e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01002880.1_2 - 0.00017 21.5 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 AAAP01002880.1_2 - 0.0014 18.8 0.4 0.0019 18.4 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01002880.1_2 - 0.081 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein TOBE PF03459.17 AAAP01002880.1_3 - 9.6e-11 41.8 1.3 1.8e-10 41.0 1.3 1.4 1 0 0 1 1 1 1 TOBE domain HTH_17 PF12728.7 AAAP01002880.1_3 - 8e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01002880.1_3 - 8.7e-05 22.5 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix MerR_1 PF13411.6 AAAP01002880.1_3 - 0.00016 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01002880.1_3 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_28 PF13518.6 AAAP01002880.1_3 - 0.00027 21.0 0.1 0.00075 19.6 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01002880.1_3 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAAP01002880.1_3 - 0.0015 17.9 0.1 0.0034 16.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 AbiEi_4 PF13338.6 AAAP01002880.1_3 - 0.0045 17.1 0.2 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin HTH_DeoR PF08220.12 AAAP01002880.1_3 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAAP01002880.1_3 - 0.047 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF746 PF05344.11 AAAP01002880.1_3 - 0.053 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF3853 PF12964.7 AAAP01002880.1_3 - 0.073 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) HTH_31 PF13560.6 AAAP01002880.1_3 - 0.12 12.7 2.4 0.26 11.7 0.4 2.4 2 2 0 2 2 2 0 Helix-turn-helix domain SBP_bac_11 PF13531.6 AAAP01002880.1_4 - 3.3e-14 53.2 0.6 3.5e-14 53.1 0.6 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01002880.1_4 - 1.4e-07 31.8 0.2 1.6e-07 31.6 0.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 AAAP01002880.1_4 - 0.054 13.2 0.2 0.061 13.0 0.2 1.0 1 0 0 1 1 1 0 PBP superfamily domain SBP_bac_8 PF13416.6 AAAP01002880.1_4 - 0.097 12.5 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein NrsF PF06532.11 AAAP01002881.1_2 - 4e-39 134.5 16.2 4.4e-39 134.3 16.2 1.0 1 0 0 1 1 1 1 Negative regulator of sigma F MatE PF01554.18 AAAP01002882.1_1 - 6.2e-28 97.5 11.2 9.9e-28 96.8 11.2 1.3 1 0 0 1 1 1 1 MatE DUF3140 PF11338.8 AAAP01002882.1_2 - 4.5e-37 126.4 0.3 5.7e-37 126.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Response_reg PF00072.24 AAAP01002883.1_2 - 2.6e-25 88.8 0.1 2.9e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain RuvA_N PF01330.21 AAAP01002883.1_3 - 7.6e-19 67.6 0.0 2.9e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 AAAP01002883.1_3 - 6.4e-12 45.9 1.7 9.3e-12 45.4 0.3 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Transposase_20 PF02371.16 AAAP01002883.1_3 - 0.00083 19.6 0.4 0.3 11.4 0.1 2.4 2 0 0 2 2 2 2 Transposase IS116/IS110/IS902 family HHH_8 PF14716.6 AAAP01002883.1_3 - 0.14 12.6 0.0 2.3 8.6 0.1 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain YceI PF04264.13 AAAP01002883.1_4 - 1.7e-41 142.2 0.0 1.9e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 YceI-like domain Chromate_transp PF02417.15 AAAP01002884.1_1 - 2.1e-34 119.0 7.7 2.6e-34 118.6 7.7 1.0 1 0 0 1 1 1 1 Chromate transporter DUF2975 PF11188.8 AAAP01002884.1_1 - 0.54 10.1 5.8 0.1 12.5 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) EAL PF00563.20 AAAP01002884.1_2 - 3.4e-62 210.1 0.0 3.8e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 EAL domain Phos_pyr_kin PF08543.12 AAAP01002886.1_1 - 9e-83 277.4 0.1 1.1e-82 277.1 0.1 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AAAP01002886.1_1 - 2.1e-05 24.0 0.0 2.8e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 AAAP01002886.1_1 - 0.18 11.2 1.4 0.72 9.2 1.4 2.0 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 AAAP01002886.1_2 - 8.3e-48 162.1 0.3 9.7e-48 161.9 0.3 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase GcrA PF07750.11 AAAP01002887.1_3 - 2.3e-05 24.9 0.4 2.4e-05 24.8 0.4 1.0 1 0 0 1 1 1 1 GcrA cell cycle regulator cNMP_binding PF00027.29 AAAP01002888.1_1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Response_reg PF00072.24 AAAP01002888.1_2 - 5.1e-21 74.9 0.0 5.9e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAAP01002888.1_2 - 0.0059 17.0 0.0 0.007 16.7 0.0 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ HAD PF12710.7 AAAP01002888.1_2 - 0.042 14.3 0.1 0.047 14.1 0.1 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TENA_THI-4 PF03070.16 AAAP01002888.1_3 - 7e-55 186.1 0.0 8e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DnaB_bind PF10410.9 AAAP01002888.1_3 - 0.18 12.0 0.6 0.7 10.1 0.2 2.2 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF1967 PF09269.11 AAAP01002888.1_3 - 0.19 11.7 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) RNA_pol_Rpb1_5 PF04998.17 AAAP01002889.1_1 - 4.1e-48 164.1 0.6 6.6e-48 163.5 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 AAAP01002889.1_1 - 6e-19 68.5 0.0 3e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AAAP01002889.1_1 - 8e-18 64.4 0.4 1.6e-17 63.4 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RnfC_N PF13375.6 AAAP01002889.1_1 - 0.0037 17.2 0.7 0.053 13.5 0.0 3.2 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 AAAP01002889.1_1 - 0.09 12.6 1.6 0.92 9.4 0.0 3.2 4 0 0 4 4 4 0 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AAAP01002889.1_1 - 0.13 12.5 0.7 0.99 9.7 0.1 2.8 1 1 2 3 3 3 0 Peptidase family M23 Peptidase_S15 PF02129.18 AAAP01002890.1_1 - 1.1e-54 185.9 1.9 1.4e-54 185.5 1.9 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 AAAP01002890.1_1 - 1.5e-21 77.4 0.0 2.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 AAAP01002890.1_1 - 0.091 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Creatininase PF02633.14 AAAP01002890.1_2 - 5.6e-06 26.0 0.0 6.3e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Abhydrolase_1 PF00561.20 AAAP01002891.1_1 - 8e-14 51.9 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01002891.1_1 - 1.2e-09 39.1 16.1 1.5e-09 38.8 16.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AAAP01002891.1_1 - 0.24 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short_C2 PF13561.6 AAAP01002891.1_2 - 3.1e-26 92.4 0.4 4.9e-26 91.7 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01002891.1_2 - 4e-26 91.7 0.0 5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 AAAP01002891.1_2 - 0.046 13.8 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 AAAP01002891.1_2 - 0.051 13.5 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding MafB19-deam PF14437.6 AAAP01002891.1_3 - 1.8e-26 92.5 0.0 2.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AAAP01002891.1_3 - 5.8e-25 87.1 0.0 7.8e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 AAAP01002891.1_3 - 0.0039 17.3 1.1 0.012 15.7 0.3 1.9 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 AAAP01002891.1_3 - 0.01 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 AAAP01002891.1_3 - 0.031 14.3 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 AAAP01002891.1_3 - 0.033 14.3 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 MAGP PF05507.11 AAAP01002891.1_3 - 0.16 12.4 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) APOBEC_N PF08210.11 AAAP01002891.1_3 - 0.19 11.6 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 AAAP01002891.1_3 - 0.19 11.8 0.0 0.27 11.3 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 AAAP01002891.1_3 - 0.22 11.6 0.0 0.29 11.2 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD_kinase PF01513.21 AAAP01002892.1_1 - 2.1e-07 30.4 0.2 5.1e-07 29.2 0.2 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAAP01002892.1_1 - 0.047 13.3 0.1 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain phage_tail_N PF08400.10 AAAP01002892.1_2 - 0.24 11.4 1.0 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Prophage tail fibre N-terminal HEPN PF05168.14 AAAP01002893.1_4 - 0.0008 19.5 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 HEPN domain GMP_synt_C PF00958.22 AAAP01002894.1_1 - 1.5e-39 133.9 0.0 2.5e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 AAAP01002894.1_1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD synthase DUF3606 PF12244.8 AAAP01002894.1_1 - 0.065 13.2 0.2 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Glyco_trans_1_4 PF13692.6 AAAP01002894.1_2 - 4.3e-19 69.3 1.1 6.3e-19 68.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01002894.1_2 - 3.3e-18 65.8 0.0 4.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01002894.1_2 - 0.00013 22.2 0.1 0.00024 21.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 SDH_C PF18317.1 AAAP01002895.1_1 - 0.00016 21.4 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain CoaE PF01121.20 AAAP01002895.1_2 - 1.3e-40 138.9 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase RNase_T PF00929.24 AAAP01002895.1_3 - 1.7e-36 126.2 0.0 2.1e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAAP01002895.1_3 - 6.1e-07 29.6 0.0 1.6e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 AAAP01002895.1_3 - 0.037 13.7 0.0 0.28 10.9 0.0 2.2 1 1 0 1 1 1 0 3'-5' exonuclease RHH_8 PF17723.1 AAAP01002895.1_4 - 3.4e-06 27.2 0.1 3.6e-06 27.1 0.1 1.0 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family Esterase_phd PF10503.9 AAAP01002895.1_5 - 1.6e-07 31.1 0.1 4.3e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase NicO PF03824.16 AAAP01002896.1_1 - 2e-14 53.6 10.8 7.8e-14 51.7 10.8 1.8 1 1 0 1 1 1 1 High-affinity nickel-transport protein DsbD_2 PF13386.6 AAAP01002896.1_1 - 2.3e-07 30.9 10.6 2e-06 27.9 5.3 2.3 2 0 0 2 2 2 2 Cytochrome C biogenesis protein transmembrane region LapA_dom PF06305.11 AAAP01002896.1_1 - 6.5e-05 22.7 4.8 0.0081 15.9 4.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 AAAP01002896.1_1 - 1.8 8.6 23.9 2.2 8.3 0.4 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_1 PF07690.16 AAAP01002896.1_2 - 5.9e-06 25.4 7.4 1.9e-05 23.8 1.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 AAAP01002897.1_2 - 2.4e-16 60.9 0.1 3.4e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01002897.1_2 - 5.2e-05 23.5 0.2 0.00013 22.2 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_tranf_2_3 PF13641.6 AAAP01002898.1_1 - 1e-20 74.7 0.0 1.5e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AAAP01002898.1_1 - 2.5e-19 69.7 0.0 3.7e-19 69.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAAP01002898.1_1 - 2.2e-09 37.0 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 AAAP01002898.1_1 - 1.2e-06 28.9 0.0 2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAAP01002898.1_1 - 0.0057 16.2 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Acyltransferase PF01553.21 AAAP01002898.1_2 - 0.015 14.9 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase Flavodoxin_2 PF02525.17 AAAP01002899.1_1 - 4.8e-17 62.3 0.0 5.3e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AAAP01002899.1_1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase FAD_binding_4 PF01565.23 AAAP01002899.1_2 - 1.5e-26 92.8 2.4 2.6e-26 92.0 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain Hemerythrin PF01814.23 AAAP01002900.1_1 - 5e-06 27.2 3.6 6.9e-06 26.7 3.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Cyclin_N PF00134.23 AAAP01002900.1_1 - 0.024 14.4 0.2 0.069 12.9 0.1 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain NinB PF05772.12 AAAP01002900.1_1 - 0.083 12.7 0.4 0.23 11.3 0.4 2.0 1 1 0 1 1 1 0 NinB protein DUF1730 PF08331.10 AAAP01002900.1_1 - 0.92 9.5 4.4 2.7 8.0 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1730) COX7a PF02238.15 AAAP01002901.1_2 - 3.1 8.2 5.7 0.86 10.0 1.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VII Acetyltransf_8 PF13523.6 AAAP01002902.1_1 - 5e-19 68.4 0.2 5.9e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3558 PF12079.8 AAAP01002902.1_2 - 1.6 8.7 14.0 1 9.3 8.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3558) ACT_7 PF13840.6 AAAP01002902.1_3 - 1.1e-14 53.9 0.0 1.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ACT domain DUF2007 PF09413.10 AAAP01002902.1_3 - 0.011 15.9 0.0 0.058 13.6 0.0 2.1 1 1 0 1 1 1 0 Putative prokaryotic signal transducing protein SecD_SecF PF02355.16 AAAP01002903.1_1 - 5.7e-16 58.5 10.8 7.6e-16 58.0 10.8 1.1 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 AAAP01002903.1_1 - 3.4e-08 32.8 17.4 5.7e-08 32.1 17.4 1.3 1 0 0 1 1 1 1 MMPL family Peptidase_S24 PF00717.23 AAAP01002904.1_2 - 3e-05 23.9 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Intein_splicing PF14890.6 AAAP01002904.1_2 - 0.22 11.5 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Intein splicing domain Ig_mannosidase PF17753.1 AAAP01002904.1_3 - 0.048 13.4 1.5 1.2 8.9 0.0 3.2 2 2 1 3 3 3 0 Ig-fold domain F5_F8_type_C PF00754.25 AAAP01002904.1_3 - 0.05 13.7 0.1 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 F5/8 type C domain PBP_dimer PF03717.15 AAAP01002904.1_4 - 2.1e-17 64.1 0.0 3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MecA_N PF05223.11 AAAP01002904.1_4 - 0.016 15.5 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain MoCF_biosynth PF00994.24 AAAP01002905.1_1 - 5.4e-15 55.3 0.5 8.3e-15 54.7 0.5 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.17 AAAP01002905.1_1 - 6.5e-13 48.7 0.6 1.2e-12 47.8 0.6 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 AAAP01002905.1_1 - 2.4e-05 24.4 2.0 2.4e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) MoeA_N PF03453.17 AAAP01002905.1_2 - 7.2e-43 146.1 4.3 7.2e-43 146.1 4.3 1.6 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) Sigma54_activat PF00158.26 AAAP01002906.1_1 - 1.9e-68 229.4 0.0 2.7e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01002906.1_1 - 1.3e-23 83.7 0.0 4.4e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01002906.1_1 - 8.7e-13 47.8 0.8 8.7e-13 47.8 0.8 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Response_reg PF00072.24 AAAP01002906.1_1 - 2.5e-09 37.3 0.0 4.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain AAA_5 PF07728.14 AAAP01002906.1_1 - 4.9e-08 33.1 0.0 9.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01002906.1_1 - 7.4e-05 23.2 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01002906.1_1 - 8.7e-05 23.0 0.0 0.00017 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 AAAP01002906.1_1 - 0.00017 21.7 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Phage_NinH PF06322.11 AAAP01002906.1_1 - 0.00031 20.6 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 Phage NinH protein HTH_30 PF13556.6 AAAP01002906.1_1 - 0.015 15.1 0.2 0.036 13.9 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mg_chelatase PF01078.21 AAAP01002906.1_1 - 0.017 14.5 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAAP01002906.1_1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_17 PF12728.7 AAAP01002906.1_1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MCM PF00493.23 AAAP01002906.1_1 - 0.21 10.7 0.0 0.5 9.4 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain ResIII PF04851.15 AAAP01002906.1_2 - 1.5e-16 60.9 0.0 1.8e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AAAP01002906.1_2 - 7.5e-06 25.8 0.0 3.5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 AAAP01002906.1_2 - 0.00083 19.1 0.0 0.0014 18.4 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 AAAP01002906.1_2 - 0.063 13.5 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAAP01002906.1_2 - 0.086 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1206 PF06724.11 AAAP01002907.1_1 - 3.2e-52 174.5 54.9 5.5e-19 68.0 14.7 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Yip1 PF04893.17 AAAP01002907.1_1 - 0.0064 16.2 20.9 0.0096 15.7 9.4 2.1 2 0 0 2 2 2 2 Yip1 domain DUF5134 PF17197.4 AAAP01002907.1_1 - 0.63 9.9 22.1 0.012 15.6 9.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5134) Sdh_cyt PF01127.22 AAAP01002907.1_1 - 2.1 8.4 16.5 2.3 8.3 0.3 3.3 1 1 2 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pep_deformylase PF01327.21 AAAP01002907.1_2 - 5.2e-39 133.4 0.0 6.2e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase TMEM190 PF15431.6 AAAP01002907.1_2 - 0.0046 17.1 0.1 0.0068 16.5 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 190 DUF3145 PF11343.8 AAAP01002907.1_3 - 5.3e-71 237.3 0.4 5.9e-71 237.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) SecA_DEAD PF07517.14 AAAP01002908.1_1 - 6.6e-116 386.7 1.3 7.7e-116 386.4 1.3 1.0 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 AAAP01002908.1_1 - 1.3e-39 135.3 1.0 3e-39 134.1 1.0 1.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 AAAP01002908.1_1 - 7.8e-06 25.8 0.0 0.0002 21.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01002908.1_1 - 0.022 14.8 1.4 0.52 10.3 0.0 2.6 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit Aminotran_5 PF00266.19 AAAP01002909.1_1 - 2.1e-139 464.6 0.0 2.4e-139 464.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAAP01002909.1_1 - 8.4e-07 28.5 0.0 1.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAAP01002909.1_1 - 9.8e-06 25.0 0.2 1.2e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAAP01002909.1_1 - 2.3e-05 23.9 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAAP01002909.1_1 - 3.4e-05 22.6 0.0 0.00013 20.6 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme SelA PF03841.13 AAAP01002909.1_1 - 0.0037 16.3 0.0 0.02 13.9 0.0 1.9 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase FeS_assembly_P PF01883.19 AAAP01002909.1_2 - 5.5e-22 77.7 0.1 8.7e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Fe-S_biosyn PF01521.20 AAAP01002909.1_3 - 5e-15 55.7 0.0 6e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ubie_methyltran PF01209.18 AAAP01002910.1_2 - 1.6e-81 273.0 0.0 2e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AAAP01002910.1_2 - 7.2e-20 71.5 0.0 1.5e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002910.1_2 - 3.7e-18 66.0 0.0 2.8e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01002910.1_2 - 3.1e-13 49.8 0.0 5.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002910.1_2 - 1.9e-11 44.6 0.0 3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002910.1_2 - 1.9e-10 40.9 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01002910.1_2 - 0.027 14.0 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain ABC1 PF03109.16 AAAP01002910.1_3 - 1.2e-31 109.3 0.1 1.7e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 ABC1 family SLBB PF10531.9 AAAP01002911.1_1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 SLBB domain CbiG_N PF11760.8 AAAP01002911.1_3 - 0.019 15.0 0.3 0.027 14.5 0.0 1.4 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal HTH_31 PF13560.6 AAAP01002911.1_4 - 1.3e-05 25.5 0.1 1.5e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01002911.1_4 - 0.00039 20.4 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix YdaS_antitoxin PF15943.5 AAAP01002911.1_4 - 0.0043 16.9 0.0 0.0065 16.3 0.0 1.3 1 1 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 AAAP01002911.1_4 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01002911.1_4 - 0.12 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain MFS_1 PF07690.16 AAAP01002912.1_1 - 8.1e-21 74.3 51.2 2.7e-11 43.0 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AAAP01002912.1_1 - 1e-08 34.0 33.8 1.5e-08 33.5 33.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Chloroplast_duf PF14476.6 AAAP01002912.1_1 - 0.38 9.7 1.2 0.56 9.1 0.0 1.8 2 0 0 2 2 2 0 Petal formation-expressed FCD PF07729.12 AAAP01002913.1_1 - 1.2e-28 100.0 8.9 1.7e-28 99.5 8.9 1.2 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01002913.1_1 - 5.6e-07 29.1 0.2 2e-06 27.3 0.2 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MFS_1 PF07690.16 AAAP01002914.1_1 - 3.2e-22 79.0 20.0 3.8e-22 78.7 20.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily YhfC PF10086.9 AAAP01002914.1_1 - 0.0028 17.1 3.1 0.0037 16.7 3.1 1.3 1 0 0 1 1 1 1 YhfC intramembrane metalloprotease MFS_1_like PF12832.7 AAAP01002914.1_1 - 0.42 9.4 10.0 0.49 9.2 10.0 1.0 1 0 0 1 1 1 0 MFS_1 like family LysR_substrate PF03466.20 AAAP01002914.1_2 - 2.8e-36 124.9 8.8 2.8e-36 124.9 8.8 1.8 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01002914.1_2 - 9.3e-16 57.5 4.1 1.7e-15 56.7 1.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family UPF0102 PF02021.17 AAAP01002915.1_2 - 2.2e-19 69.5 0.2 2.7e-19 69.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NucS PF01939.16 AAAP01002915.1_2 - 0.00035 20.0 0.0 0.00045 19.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease NucS DUF4143 PF13635.6 AAAP01002915.1_2 - 0.018 15.2 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) SfsA PF03749.13 AAAP01002915.1_2 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain NERD PF08378.11 AAAP01002915.1_2 - 0.17 12.4 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Nuclease-related domain Response_reg PF00072.24 AAAP01002915.1_3 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Response regulator receiver domain SIR2 PF02146.17 AAAP01002916.1_2 - 4.4e-44 150.5 0.0 5.3e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Glyco_trans_1_4 PF13692.6 AAAP01002916.1_2 - 0.012 16.1 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 PNTB PF02233.16 AAAP01002916.1_2 - 0.051 12.5 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Zn-ribbon_8 PF09723.10 AAAP01002916.1_2 - 0.16 12.1 1.9 0.44 10.7 1.9 1.7 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 AAAP01002916.1_2 - 0.28 11.2 1.4 0.48 10.4 1.4 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 AAAP01002916.1_2 - 0.82 9.2 5.5 12 5.5 5.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain CorC_HlyC PF03471.17 AAAP01002916.1_3 - 4.2e-22 78.0 0.3 2.9e-21 75.3 0.1 1.9 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AAAP01002916.1_3 - 2e-05 24.9 0.0 4.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 CBS domain ABC_membrane PF00664.23 AAAP01002917.1_1 - 7.6e-50 170.1 0.2 8.8e-50 169.9 0.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane_3 PF13748.6 AAAP01002917.1_1 - 0.00039 19.8 1.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region DUF2207 PF09972.9 AAAP01002917.1_1 - 0.14 10.9 4.4 0.11 11.3 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Acyl-CoA_dh_M PF02770.19 AAAP01002919.1_1 - 1.2e-15 57.5 0.0 2.8e-15 56.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 AAAP01002919.1_1 - 3.1e-05 24.2 4.8 0.00076 19.7 4.8 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAAP01002919.1_1 - 0.00062 20.4 0.6 0.0015 19.2 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_C PF12806.7 AAAP01002919.1_2 - 1.3e-31 109.3 0.2 1.5e-31 109.1 0.2 1.1 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Thiolase_N PF00108.23 AAAP01002919.1_3 - 2.7e-05 23.7 0.0 3e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding PF00501.28 AAAP01002920.1_2 - 1.4e-45 155.7 0.0 1.7e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF3320 PF11784.8 AAAP01002920.1_4 - 0.024 14.6 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Aldo_ket_red PF00248.21 AAAP01002921.1_1 - 4.1e-64 216.6 0.0 4.8e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SprB PF13573.6 AAAP01002921.1_2 - 0.018 14.8 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 SprB repeat Aminotran_1_2 PF00155.21 AAAP01002922.1_1 - 5.6e-51 173.8 0.0 6.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAAP01002922.1_1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 AAAP01002922.1_1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V UvrD_C PF13361.6 AAAP01002923.1_1 - 1.7e-09 37.5 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AAAP01002923.1_1 - 7.3e-09 35.3 0.6 0.0054 16.5 0.5 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 AAAP01002923.1_1 - 2.4e-05 24.4 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily ABC_tran PF00005.27 AAAP01002924.1_1 - 8.6e-30 104.0 0.0 1.2e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002924.1_1 - 8.5e-10 38.9 0.4 5.9e-06 26.3 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01002924.1_1 - 0.00033 21.2 0.0 0.00048 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01002924.1_1 - 0.00045 19.9 0.1 0.00081 19.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAAP01002924.1_1 - 0.00067 19.2 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01002924.1_1 - 0.00075 19.9 0.3 0.0015 18.9 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01002924.1_1 - 0.0013 18.1 0.0 0.0042 16.5 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 AAAP01002924.1_1 - 0.0055 16.5 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAAP01002924.1_1 - 0.0055 16.8 0.1 0.22 11.6 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01002924.1_1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Adeno_IVa2 PF02456.15 AAAP01002924.1_1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 AAAP01002924.1_1 - 0.035 14.4 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01002924.1_1 - 0.043 14.0 0.1 0.093 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01002924.1_1 - 0.076 13.0 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 AAAP01002924.1_1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 AAAP01002924.1_1 - 0.08 12.6 0.1 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AAAP01002924.1_1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAAP01002924.1_1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 AAAP01002924.1_1 - 0.13 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AAAP01002924.1_1 - 0.2 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain FecCD PF01032.18 AAAP01002924.1_2 - 6.4e-36 123.9 9.2 7.6e-36 123.7 9.2 1.0 1 0 0 1 1 1 1 FecCD transport family TMP-TENI PF02581.17 AAAP01002925.1_1 - 6.9e-51 172.2 0.0 7.9e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase Lysine_decarbox PF03641.14 AAAP01002925.1_2 - 1.4e-44 151.4 0.0 1.6e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAAP01002925.1_2 - 1.5e-17 63.6 0.4 1.9e-17 63.3 0.4 1.1 1 0 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 AAAP01002925.1_2 - 0.055 12.7 0.3 0.066 12.4 0.3 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DUF4175 PF13779.6 AAAP01002926.1_1 - 7.5e-72 242.5 14.5 8.5e-72 242.3 14.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) EAL PF00563.20 AAAP01002927.1_1 - 2e-73 246.9 0.0 2.2e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 EAL domain Glycos_transf_1 PF00534.20 AAAP01002927.1_3 - 1.7e-20 73.3 0.0 2.1e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01002927.1_3 - 9.1e-17 61.7 0.0 1.1e-16 61.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01002927.1_3 - 4.2e-09 36.7 0.1 6.3e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M20 PF01546.28 AAAP01002928.1_1 - 3e-41 141.4 0.1 4.1e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAAP01002928.1_1 - 4.1e-22 78.1 0.1 6.6e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Oxidored_molyb PF00174.19 AAAP01002929.1_1 - 4.8e-47 159.8 0.0 5.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Gp138_N PF18352.1 AAAP01002930.1_4 - 5.1e-21 74.6 0.0 7.7e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Phage protein Gp138 N-terminal domain Sulfotransfer_2 PF03567.14 AAAP01002931.1_2 - 0.00043 20.3 0.1 0.0013 18.7 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family DUF3325 PF11804.8 AAAP01002931.1_4 - 5.3e-09 36.1 6.7 5.3e-09 36.1 6.7 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3325) AFG1_ATPase PF03969.16 AAAP01002932.1_2 - 1.8e-43 148.9 0.0 2.1e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase TetR_C_11 PF16859.5 AAAP01002932.1_2 - 0.031 14.6 2.6 0.035 14.4 0.2 2.0 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Proton_antipo_M PF00361.20 AAAP01002933.1_1 - 9.6e-58 195.7 23.0 1.4e-57 195.1 23.0 1.2 1 0 0 1 1 1 1 Proton-conducting membrane transporter Molybdopterin PF00384.22 AAAP01002934.1_1 - 1.4e-34 119.9 0.0 2.1e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01002934.1_1 - 2e-27 95.4 0.1 3.7e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain FdsD PF11390.8 AAAP01002934.1_2 - 7.3e-25 87.1 0.1 9.4e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 NADH-dependant formate dehydrogenase delta subunit FdsD HTH_1 PF00126.27 AAAP01002934.1_3 - 3.5e-13 49.3 0.1 3.7e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AAAP01002934.1_3 - 0.0021 18.1 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01002934.1_3 - 0.015 15.2 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 AAAP01002934.1_3 - 0.032 14.3 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01002934.1_3 - 0.054 13.3 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Clp_N PF02861.20 AAAP01002934.1_3 - 0.072 13.2 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Response_reg PF00072.24 AAAP01002936.1_1 - 2.2e-46 156.7 0.0 2.4e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01002936.1_1 - 5.5e-19 68.7 0.0 1e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TusA PF01206.17 AAAP01002936.1_1 - 0.0023 17.7 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 2 Sulfurtransferase TusA NepR PF18557.1 AAAP01002936.1_1 - 0.0097 15.5 0.4 0.022 14.4 0.4 1.6 1 0 0 1 1 1 1 Anti-sigma factor NepR ResB PF05140.14 AAAP01002936.1_1 - 0.17 10.6 0.6 3.4 6.3 0.1 2.0 2 0 0 2 2 2 0 ResB-like family Response_reg PF00072.24 AAAP01002936.1_2 - 1.4e-20 73.5 0.0 2.6e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01002936.1_2 - 2.7e-16 58.8 0.7 4.6e-16 58.1 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01002936.1_2 - 2.1e-06 27.3 0.2 4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01002936.1_2 - 0.0019 17.7 0.3 0.0042 16.6 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AAAP01002936.1_2 - 0.004 17.6 0.3 0.0079 16.6 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2089 PF09862.9 AAAP01002936.1_2 - 0.018 15.1 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_23 PF13384.6 AAAP01002936.1_2 - 0.027 14.3 0.1 0.12 12.2 0.0 2.1 1 1 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 AAAP01002936.1_2 - 0.028 14.5 1.0 0.055 13.5 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.22 AAAP01002936.1_2 - 0.16 11.9 0.9 0.73 9.8 0.2 2.3 2 0 0 2 2 2 0 MarR family DUF3071 PF11268.8 AAAP01002936.1_2 - 0.18 11.8 1.3 2.4 8.2 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3071) p450 PF00067.22 AAAP01002937.1_2 - 4.8e-10 38.8 0.0 3.8e-08 32.5 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 AAAP01002938.1_1 - 1.1e-16 60.8 17.4 1.4e-16 60.4 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 AAAP01002938.1_1 - 0.0068 14.7 2.1 0.0095 14.2 2.1 1.1 1 0 0 1 1 1 1 BT1 family HlyD_D23 PF16576.5 AAAP01002938.1_2 - 2.8e-20 72.5 8.7 6.8e-18 64.7 8.7 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01002938.1_2 - 2.8e-19 69.8 6.9 4.3e-16 59.5 0.1 3.4 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01002938.1_2 - 5.1e-12 45.4 8.2 2.9e-11 43.0 0.8 3.5 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD PF00529.20 AAAP01002938.1_2 - 2.4e-10 40.2 0.0 4.9e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAAP01002938.1_2 - 0.00044 20.0 0.1 0.16 11.8 0.1 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme DUF16 PF01519.16 AAAP01002938.1_2 - 0.21 12.1 1.3 1 9.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 CCDC144C PF14915.6 AAAP01002938.1_2 - 0.43 9.6 6.6 0.03 13.4 1.3 1.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF4407 PF14362.6 AAAP01002938.1_2 - 0.64 9.3 15.6 0.97 8.7 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 AAAP01002938.1_2 - 1.5 8.6 7.1 0.24 11.2 1.0 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 TetR_N PF00440.23 AAAP01002938.1_3 - 5.5e-20 70.9 1.7 8.7e-20 70.3 0.6 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.12 AAAP01002938.1_3 - 0.0032 17.1 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01002938.1_3 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain MerR PF00376.23 AAAP01002938.1_3 - 0.019 14.7 0.1 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 MerR family regulatory protein HTH_Tnp_1_2 PF13022.6 AAAP01002938.1_3 - 0.047 13.8 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LacI PF00356.21 AAAP01002938.1_3 - 0.053 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Sigma70_r4 PF04545.16 AAAP01002938.1_3 - 0.074 12.6 0.1 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 AAAP01002938.1_3 - 0.16 11.8 0.4 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4012 PF13196.6 AAAP01002939.1_1 - 9.2e-30 104.0 0.1 9.9e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4012) Mo-co_dimer PF03404.16 AAAP01002940.1_1 - 2.1e-05 24.5 0.0 5.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 AAAP01002940.1_1 - 0.018 14.9 1.1 0.027 14.4 0.2 1.8 2 0 0 2 2 2 0 BNR/Asp-box repeat Cytochrom_C PF00034.21 AAAP01002940.1_2 - 0.00053 21.1 1.9 0.12 13.6 0.2 2.2 1 1 1 2 2 2 2 Cytochrome c PepSY_2 PF13670.6 AAAP01002940.1_2 - 0.0044 17.0 0.6 0.0044 17.0 0.6 1.5 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain Cytochrome_CBB3 PF13442.6 AAAP01002940.1_2 - 0.014 15.7 0.8 0.096 13.0 0.8 2.0 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Dehyd-heme_bind PF09098.10 AAAP01002940.1_2 - 0.02 14.5 0.0 0.034 13.8 0.0 1.4 1 1 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding YbgS PF13985.6 AAAP01002940.1_2 - 0.23 11.7 0.5 0.29 11.4 0.5 1.2 1 0 0 1 1 1 0 YbgS-like protein Lactonase PF10282.9 AAAP01002940.1_3 - 1.2e-08 34.6 0.0 4.5e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AAAP01002940.1_3 - 3.2e-08 32.5 0.0 0.00033 19.3 0.0 3.6 1 1 3 4 4 4 4 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 AAAP01002940.1_3 - 0.054 12.3 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Proteasome_A_N PF10584.9 AAAP01002940.1_3 - 0.15 11.8 4.7 0.59 9.9 0.1 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Sulfate_transp PF00916.20 AAAP01002941.1_2 - 3.3e-12 45.9 5.3 3.7e-12 45.7 5.3 1.0 1 0 0 1 1 1 1 Sulfate permease family PTS_EIIC PF02378.18 AAAP01002941.1_2 - 0.0095 15.0 2.6 0.0095 15.0 2.6 1.4 1 1 0 1 1 1 1 Phosphotransferase system, EIIC FUN14 PF04930.15 AAAP01002941.1_2 - 0.087 13.3 0.9 0.14 12.6 0.9 1.3 1 0 0 1 1 1 0 FUN14 family HTH_18 PF12833.7 AAAP01002942.1_1 - 4.1e-13 49.4 2.3 5.7e-13 48.9 1.3 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01002942.1_1 - 0.0034 17.5 0.1 1.4 9.1 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family MFS_1 PF07690.16 AAAP01002942.1_2 - 5.9e-28 97.8 36.9 7.2e-28 97.5 36.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 AAAP01002942.1_2 - 2e-06 26.4 1.4 0.0036 15.7 0.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family GGDEF PF00990.21 AAAP01002943.1_1 - 6.9e-16 58.4 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Peptidase_U4 PF03419.13 AAAP01002943.1_1 - 1.3 8.2 3.9 1.9 7.7 3.9 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Trypsin_2 PF13365.6 AAAP01002943.1_2 - 4.7e-31 108.7 0.1 1.2e-30 107.4 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAAP01002943.1_2 - 1.5e-23 82.9 0.5 3.7e-13 49.6 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 AAAP01002943.1_2 - 5.1e-22 77.5 2.3 7.8e-10 38.5 0.0 3.8 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 AAAP01002943.1_2 - 5e-17 62.0 1.9 4.8e-07 30.0 0.0 3.7 4 0 0 4 4 4 2 PDZ domain Trypsin PF00089.26 AAAP01002943.1_2 - 8.5e-17 61.7 0.0 1.7e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AAAP01002943.1_2 - 9.1e-08 32.0 0.2 0.01 15.8 0.0 3.2 3 1 0 3 3 3 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 AAAP01002943.1_2 - 0.00015 21.7 0.0 0.97 9.5 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Peptidase_S46 PF10459.9 AAAP01002943.1_2 - 1.4 7.4 3.8 0.58 8.7 0.3 2.0 2 1 1 3 3 3 0 Peptidase S46 AA_permease_2 PF13520.6 AAAP01002944.1_2 - 9.5e-20 70.8 1.6 9.9e-20 70.7 1.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01002944.1_2 - 0.00063 18.5 0.7 0.00065 18.4 0.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF898 PF05987.13 AAAP01002945.1_1 - 1e-35 123.4 3.1 1.2e-35 123.2 3.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF4728 PF15860.5 AAAP01002945.1_1 - 0.064 13.9 3.4 0.17 12.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) Peptidase_M48 PF01435.18 AAAP01002945.1_2 - 1.1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AAAP01002945.1_2 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 ABC_tran PF00005.27 AAAP01002946.1_1 - 1.2e-29 103.6 0.0 1.8e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01002946.1_1 - 1.5e-08 35.2 0.6 2.6e-08 34.5 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01002946.1_1 - 4e-07 30.1 0.4 0.013 15.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01002946.1_1 - 1.5e-05 25.0 0.0 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 AAAP01002946.1_1 - 8.1e-05 22.9 0.1 0.00023 21.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01002946.1_1 - 0.0002 21.4 0.0 0.0011 19.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 AAAP01002946.1_1 - 0.0017 18.0 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AAAP01002946.1_1 - 0.0017 17.2 0.1 1.1 8.0 0.0 2.5 2 1 0 2 2 2 2 Predicted ATPase of the ABC class SMC_N PF02463.19 AAAP01002946.1_1 - 0.002 17.6 0.0 0.24 10.8 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAAP01002946.1_1 - 0.0025 17.6 0.3 0.01 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AAAP01002946.1_1 - 0.0025 18.0 0.0 0.0044 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01002946.1_1 - 0.003 17.8 0.0 0.088 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AAAP01002946.1_1 - 0.0031 17.2 0.1 0.006 16.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AAAP01002946.1_1 - 0.0061 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 AAAP01002946.1_1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 AAAP01002946.1_1 - 0.018 15.2 0.0 0.044 14.0 0.0 1.6 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 AAAP01002946.1_1 - 0.026 13.8 0.1 0.067 12.5 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin DUF87 PF01935.17 AAAP01002946.1_1 - 0.028 14.5 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 AAAP01002946.1_1 - 0.03 14.8 0.0 0.21 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 AAAP01002946.1_1 - 0.048 12.6 0.1 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 AAAP01002946.1_1 - 0.076 13.0 0.2 0.54 10.3 0.0 2.5 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) Ras PF00071.22 AAAP01002946.1_1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras family NTPase_1 PF03266.15 AAAP01002946.1_1 - 0.11 12.3 0.5 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 AAAP01002946.1_1 - 0.12 12.4 0.3 0.32 11.1 0.3 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain LSDAT_prok PF18171.1 AAAP01002946.1_1 - 0.13 11.4 0.3 0.29 10.4 0.1 1.6 2 0 0 2 2 1 0 SLOG in TRPM, prokaryote Septin PF00735.18 AAAP01002946.1_1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 AAAP01002946.1_1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AAAP01002946.1_1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 AAAP01002946.1_1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 AAAP01002946.1_1 - 0.24 11.8 0.0 0.44 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 AAAP01002946.1_1 - 0.25 11.2 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MobB PF03205.14 AAAP01002946.1_1 - 0.27 11.1 1.2 0.33 10.8 0.1 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B BPD_transp_1 PF00528.22 AAAP01002946.1_2 - 5.9e-17 62.0 19.7 8.1e-17 61.5 19.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component HATPase_c PF02518.26 AAAP01002947.1_1 - 2.2e-15 57.1 0.0 4.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01002947.1_1 - 8.8e-12 44.9 0.1 1.9e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01002947.1_1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4141 PF13605.6 AAAP01002947.1_1 - 0.047 12.9 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) DivIC PF04977.15 AAAP01002947.1_1 - 0.14 12.0 0.6 0.28 11.0 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator HATPase_c_5 PF14501.6 AAAP01002947.1_1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 GHKL domain DUF2500 PF10694.9 AAAP01002947.1_1 - 0.21 12.1 0.0 0.58 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF4381 PF14316.6 AAAP01002947.1_1 - 2.1 8.6 5.0 18 5.5 5.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Response_reg PF00072.24 AAAP01002947.1_2 - 3e-11 43.5 0.1 3.4e-11 43.3 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DNA_pol3_alpha PF07733.12 AAAP01002948.1_1 - 4.9e-82 275.4 0.0 2.8e-81 273.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAAP01002948.1_1 - 5.4e-58 195.0 0.0 8.6e-58 194.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain HHH_6 PF14579.6 AAAP01002948.1_1 - 6.7e-26 90.4 0.0 1.4e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Malate_synthase PF01274.22 AAAP01002948.1_1 - 0.078 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Malate synthase EAL PF00563.20 AAAP01002949.1_1 - 8e-74 248.1 0.0 9.4e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01002949.1_1 - 0.00015 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HTH_8 PF02954.19 AAAP01002949.1_2 - 5.2e-08 32.5 0.1 5.2e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 AAAP01002949.1_2 - 1.6e-05 24.4 0.1 2.9e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AAAP01002949.1_2 - 0.0064 16.3 0.1 0.055 13.3 0.0 2.3 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_17 PF12728.7 AAAP01002949.1_2 - 0.041 14.1 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01002949.1_2 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma54_activat PF00158.26 AAAP01002949.1_3 - 1.7e-47 161.3 0.0 2.1e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01002949.1_3 - 9.6e-10 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AAAP01002949.1_3 - 0.011 15.7 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TetR_C_6 PF13977.6 AAAP01002950.1_1 - 0.034 14.4 0.2 0.034 14.4 0.2 1.0 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Peptidase_Mx PF15887.5 AAAP01002950.1_2 - 5e-98 327.2 0.0 6e-98 326.9 0.0 1.1 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase zinc-ribbon_6 PF10005.9 AAAP01002950.1_2 - 9.9e-25 87.1 0.6 1.6e-24 86.4 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_Mx1 PF15890.5 AAAP01002950.1_2 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.3 1 1 0 1 1 1 1 Putative zinc-binding metallo-peptidase Bact_transglu_N PF08379.10 AAAP01002950.1_3 - 5.6e-29 100.9 0.5 9.5e-29 100.1 0.5 1.4 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAAP01002950.1_3 - 1.7e-19 70.3 0.0 2.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAAP01002950.1_3 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain ABC2_membrane_3 PF12698.7 AAAP01002951.1_1 - 1.7e-16 60.3 3.0 5.8e-11 42.1 2.3 2.0 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAAP01002951.1_1 - 0.036 13.5 2.5 0.97 8.8 0.0 2.3 2 0 0 2 2 2 0 ABC-2 type transporter Gate PF07670.14 AAAP01002951.1_1 - 0.14 12.4 3.0 0.46 10.8 1.3 2.1 2 0 0 2 2 2 0 Nucleoside recognition ABC2_membrane_2 PF12679.7 AAAP01002951.1_1 - 2.1 7.5 7.2 4.9 6.3 7.2 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Mur_ligase_M PF08245.12 AAAP01002952.1_2 - 0.2 11.6 2.2 0.26 11.2 2.2 1.1 1 0 0 1 1 1 0 Mur ligase middle domain Angiomotin_C PF12240.8 AAAP01002953.1_1 - 0.0016 18.0 3.5 0.0027 17.3 3.5 1.3 1 0 0 1 1 1 1 Angiomotin C terminal PikAIV_N PF18605.1 AAAP01002953.1_1 - 0.029 13.9 1.3 0.097 12.3 0.2 2.4 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Mod_r PF07200.13 AAAP01002953.1_1 - 0.036 14.2 0.5 0.054 13.6 0.5 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DAO PF01266.24 AAAP01002953.1_1 - 0.088 12.4 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NPV_P10 PF05531.12 AAAP01002953.1_1 - 0.19 12.2 0.2 12 6.4 0.0 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RmlD_sub_bind PF04321.17 AAAP01002953.1_2 - 6.3e-18 64.9 0.0 1.4e-17 63.7 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAAP01002953.1_2 - 7.6e-06 25.5 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2866 PF11065.8 AAAP01002953.1_2 - 0.048 13.7 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Polysacc_synt_2 PF02719.15 AAAP01002953.1_3 - 4.8e-07 29.2 0.0 5e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Lamprin PF06403.11 AAAP01002954.1_1 - 0.01 15.8 8.7 0.01 15.8 8.7 1.8 2 0 0 2 2 2 0 Lamprin DUF1036 PF06282.11 AAAP01002954.1_2 - 7.7e-43 145.6 0.5 9.2e-43 145.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1036) MOFRL PF05161.13 AAAP01002954.1_3 - 1.5e-33 115.2 3.9 1.9e-33 114.9 3.9 1.1 1 0 0 1 1 1 1 MOFRL family PNP_UDP_1 PF01048.20 AAAP01002955.1_1 - 2.9e-10 39.8 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily AMNp_N PF10423.9 AAAP01002955.1_2 - 9e-47 158.6 0.0 1.1e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial AMP nucleoside phosphorylase N-terminus TrmO PF01980.16 AAAP01002955.1_3 - 4.5e-28 97.9 0.0 5.3e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O TonB_dep_Rec PF00593.24 AAAP01002955.1_4 - 2.7e-09 37.4 2.3 2.9e-09 37.3 2.3 1.0 1 0 0 1 1 1 1 TonB dependent receptor Flg_bbr_C PF06429.13 AAAP01002956.1_1 - 1.7e-17 63.3 0.0 3.4e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal RHS_repeat PF05593.14 AAAP01002956.1_1 - 0.01 16.4 0.6 0.023 15.2 0.2 1.8 2 0 0 2 2 2 0 RHS Repeat HemolysinCabind PF00353.19 AAAP01002957.1_1 - 1.2e-24 85.9 102.0 8.6e-06 25.6 1.6 8.7 7 0 0 7 7 7 7 RTX calcium-binding nonapeptide repeat (4 copies) Cpn10 PF00166.21 AAAP01002957.1_1 - 6.3 6.9 15.0 1.3 9.1 0.6 4.8 2 1 3 5 5 5 0 Chaperonin 10 Kd subunit Peripla_BP_5 PF13433.6 AAAP01002958.1_1 - 4.5e-120 401.0 0.2 5e-120 400.8 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AAAP01002958.1_1 - 4.7e-60 204.1 0.2 5.2e-60 203.9 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein FTR_C PF02741.15 AAAP01002958.1_1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 FTR, proximal lobe BPD_transp_2 PF02653.16 AAAP01002958.1_2 - 1.3e-38 132.8 25.7 1.6e-38 132.4 25.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Trans_reg_C PF00486.28 AAAP01002959.1_1 - 6.7e-23 80.6 0.0 1.2e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01002959.1_1 - 0.0045 17.1 0.0 0.0079 16.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01002959.1_1 - 0.033 13.7 0.2 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sensor_TM1 PF13755.6 AAAP01002959.1_2 - 1.6e-28 98.2 4.0 1.6e-28 98.2 4.0 1.8 2 0 0 2 2 2 1 Sensor N-terminal transmembrane domain Stimulus_sens_1 PF13756.6 AAAP01002959.1_2 - 1.4e-26 93.2 0.2 2.4e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 Stimulus-sensing domain AAA_lid_9 PF17871.1 AAAP01002960.1_1 - 5.1e-34 116.3 5.3 2.4e-33 114.2 5.3 2.2 1 0 0 1 1 1 1 AAA lid domain Clp_N PF02861.20 AAAP01002960.1_1 - 1.8e-28 98.4 2.4 7.3e-16 58.0 0.1 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 AAAP01002960.1_1 - 4.9e-21 75.5 0.8 1.1e-15 58.2 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AAAP01002960.1_1 - 2.2e-12 47.5 1.6 6.4e-10 39.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AAAP01002960.1_1 - 8.4e-10 39.3 10.7 0.00036 21.0 0.1 5.3 4 1 1 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 AAAP01002960.1_1 - 1.7e-08 34.6 0.3 0.0052 16.8 0.0 3.0 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAAP01002960.1_1 - 4.2e-07 30.3 0.5 0.01 16.1 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_7 PF12775.7 AAAP01002960.1_1 - 2.5e-06 27.1 0.0 0.057 12.9 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAAP01002960.1_1 - 5.7e-06 26.2 0.0 0.17 11.6 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AAAP01002960.1_1 - 5.9e-06 26.3 0.4 0.89 9.4 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 AAAP01002960.1_1 - 1.1e-05 26.0 1.6 0.28 11.7 0.0 3.6 4 0 0 4 4 3 2 AAA domain TniB PF05621.11 AAAP01002960.1_1 - 8e-05 22.1 0.0 0.045 13.2 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 AAAP01002960.1_1 - 0.00011 22.0 0.1 0.18 11.5 0.0 2.9 2 2 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 AAAP01002960.1_1 - 0.00011 22.0 1.6 0.61 9.8 0.0 3.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AAAP01002960.1_1 - 0.00016 21.6 0.9 0.26 11.2 0.0 3.6 5 0 0 5 5 3 1 NACHT domain Mg_chelatase PF01078.21 AAAP01002960.1_1 - 0.00018 21.0 0.0 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 AAAP01002960.1_1 - 0.0002 21.4 4.8 1.5 8.7 0.1 3.9 3 1 0 4 4 4 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AAAP01002960.1_1 - 0.00033 21.0 0.0 0.99 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Roc PF08477.13 AAAP01002960.1_1 - 0.00042 20.5 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 AAAP01002960.1_1 - 0.00053 20.0 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AAAP01002960.1_1 - 0.00075 19.8 2.2 0.68 10.2 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 AAAP01002960.1_1 - 0.00093 19.2 0.0 0.077 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAAP01002960.1_1 - 0.0013 19.1 0.4 0.075 13.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 AAAP01002960.1_1 - 0.0016 17.7 0.1 0.093 11.9 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 AAAP01002960.1_1 - 0.0022 17.7 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 AAAP01002960.1_1 - 0.0025 17.8 0.3 1.5 8.8 0.0 3.7 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 AAAP01002960.1_1 - 0.0031 17.7 0.8 4.6 7.4 0.0 3.5 4 0 0 4 4 2 0 AAA domain ABC_tran PF00005.27 AAAP01002960.1_1 - 0.0052 17.3 0.6 2.7 8.5 0.0 3.3 4 0 0 4 4 2 1 ABC transporter ABC_tran_CTD PF16326.5 AAAP01002960.1_1 - 0.01 16.1 7.8 0.01 16.1 7.8 2.7 3 0 0 3 3 1 0 ABC transporter C-terminal domain Zeta_toxin PF06414.12 AAAP01002960.1_1 - 0.011 15.1 0.7 2.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 AAAP01002960.1_1 - 0.012 15.2 0.1 1.4 8.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAAP01002960.1_1 - 0.013 15.3 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 AAAP01002960.1_1 - 0.019 14.1 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF3500 PF12006.8 AAAP01002960.1_1 - 0.065 12.7 1.9 0.11 12.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF87 PF01935.17 AAAP01002960.1_1 - 0.2 11.8 3.0 5 7.1 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain LMBR1 PF04791.16 AAAP01002960.1_1 - 0.41 9.5 2.1 0.63 8.9 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 AAAP01002960.1_1 - 0.43 11.2 10.2 0.075 13.6 3.2 3.1 4 0 0 4 4 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ras PF00071.22 AAAP01002960.1_1 - 0.44 10.1 3.0 21 4.7 0.0 3.7 4 0 0 4 4 4 0 Ras family DUF4407 PF14362.6 AAAP01002960.1_1 - 0.57 9.5 9.6 1.1 8.5 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 AAAP01002960.1_1 - 0.85 9.9 11.0 11 6.3 7.6 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) zf-CpG_bind_C PF12269.8 AAAP01002960.1_1 - 1.1 9.0 4.1 0.49 10.1 1.7 1.6 2 0 0 2 2 1 0 CpG binding protein zinc finger C terminal domain NTPase_1 PF03266.15 AAAP01002960.1_1 - 1.6 8.6 8.6 6.8 6.6 0.1 3.9 4 1 0 5 5 4 0 NTPase Acyl-CoA_dh_2 PF08028.11 AAAP01002960.1_1 - 2.4 8.4 8.0 2.8 8.2 6.3 2.0 2 0 0 2 2 1 0 Acyl-CoA dehydrogenase, C-terminal domain MnmE_helical PF12631.7 AAAP01002960.1_1 - 2.7 8.1 8.8 41 4.3 0.0 2.9 2 1 1 3 3 3 0 MnmE helical domain Vir_act_alpha_C PF10400.9 AAAP01002960.1_1 - 7.1 7.4 7.8 11 6.8 4.9 2.9 2 1 0 2 2 1 0 Virulence activator alpha C-term Aldo_ket_red PF00248.21 AAAP01002961.1_1 - 2.2e-38 132.1 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ald_Xan_dh_C2 PF02738.18 AAAP01002962.1_1 - 6.8e-65 219.6 0.4 6.4e-35 120.6 0.0 3.1 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01002962.1_1 - 7.4e-05 23.1 0.2 0.00059 20.2 0.1 2.3 1 1 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Helicase_C PF00271.31 AAAP01002963.1_1 - 1e-29 103.1 0.0 2.8e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAAP01002963.1_1 - 5.6e-27 94.6 0.0 8.1e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase UTP25 PF06862.12 AAAP01002963.1_1 - 0.049 12.4 0.0 3.2 6.4 0.0 2.8 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 AAAP01002963.1_1 - 0.085 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GGDEF PF00990.21 AAAP01002963.1_3 - 7e-39 133.2 0.0 9.3e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HR1 PF02185.16 AAAP01002963.1_3 - 0.013 15.6 1.3 0.027 14.6 1.3 1.5 1 0 0 1 1 1 0 Hr1 repeat T3SS_needle_E PF08988.10 AAAP01002963.1_3 - 0.095 12.9 0.9 0.095 12.9 0.9 1.9 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle PNP_UDP_1 PF01048.20 AAAP01002964.1_1 - 1.6e-06 27.6 0.5 1.7e-06 27.5 0.5 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Autotransporter PF03797.19 AAAP01002964.1_3 - 1.5e-30 106.7 17.9 1.5e-30 106.7 17.9 1.7 2 1 0 2 2 2 1 Autotransporter beta-domain Fanconi_A PF03511.14 AAAP01002965.1_1 - 0.085 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein MerR PF00376.23 AAAP01002966.1_1 - 4.3e-18 64.8 0.3 8.6e-18 63.8 0.3 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 AAAP01002966.1_1 - 1.3e-15 57.2 0.0 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AAAP01002966.1_1 - 1.9e-07 31.5 0.0 3.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 MerR, DNA binding AbiEi_4 PF13338.6 AAAP01002966.1_1 - 0.02 15.1 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Hydrolase PF00702.26 AAAP01002966.1_2 - 5.8e-37 128.0 7.9 1.8e-36 126.4 6.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01002966.1_2 - 3e-06 27.2 0.8 0.0019 18.0 0.5 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01002966.1_2 - 3.5e-06 27.5 3.1 2.7e-05 24.7 3.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01002966.1_2 - 0.017 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LamB_YcsF PF03746.16 AAAP01002966.1_2 - 0.055 13.1 0.6 0.099 12.3 0.6 1.5 1 1 0 1 1 1 0 LamB/YcsF family DUF1846 PF08903.11 AAAP01002966.1_2 - 0.19 10.3 0.0 3.7 6.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) MoCF_biosynth PF00994.24 AAAP01002967.1_1 - 8e-25 87.2 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.17 AAAP01002967.1_1 - 1.7e-21 76.6 0.3 3.8e-21 75.5 0.3 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 AAAP01002967.1_1 - 7.5e-15 54.9 0.0 2.3e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PBP_like PF12727.7 AAAP01002967.1_2 - 9.8e-13 47.6 0.0 1.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain MFS_1 PF07690.16 AAAP01002968.1_1 - 2.4e-06 26.7 42.4 2.4e-06 26.7 42.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TLC PF03219.14 AAAP01002968.1_1 - 6.8e-05 21.8 12.2 0.011 14.5 5.4 3.5 2 1 0 2 2 2 2 TLC ATP/ADP transporter DUF1007 PF06226.13 AAAP01002969.1_2 - 3.7e-64 216.6 0.0 4.2e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1007) EF-hand_5 PF13202.6 AAAP01002969.1_2 - 4.2e-05 22.9 0.1 8.6e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 AAAP01002969.1_2 - 0.0047 16.4 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 AAAP01002969.1_2 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain CcmH PF03918.14 AAAP01002969.1_3 - 6.2e-52 174.7 0.0 7.6e-52 174.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF202 PF02656.15 AAAP01002969.1_3 - 0.055 13.9 0.4 0.39 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF1206 PF06724.11 AAAP01002969.1_3 - 0.25 11.4 3.1 0.77 9.9 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4381 PF14316.6 AAAP01002969.1_3 - 0.38 11.0 2.8 0.41 10.9 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PEP-CTERM PF07589.11 AAAP01002969.1_3 - 7 6.9 8.7 1.6 8.9 1.4 2.4 2 0 0 2 2 2 0 PEP-CTERM motif CcmF_C PF16327.5 AAAP01002969.1_4 - 5.4e-60 203.4 1.2 6.1e-60 203.2 1.2 1.0 1 0 0 1 1 1 1 Cytochrome c-type biogenesis protein CcmF C-terminal ResB PF05140.14 AAAP01002969.1_4 - 0.11 11.2 0.0 0.11 11.2 0.0 1.9 2 1 0 3 3 3 0 ResB-like family DUF3040 PF11239.8 AAAP01002969.1_4 - 1.2 9.4 15.3 0.6 10.4 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Acetyltransf_10 PF13673.7 AAAP01002970.1_1 - 2.6e-11 43.5 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01002970.1_1 - 6.4e-08 32.8 0.0 6.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 AAAP01002970.1_1 - 1.9e-07 30.9 0.0 2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_7 PF13508.7 AAAP01002970.1_1 - 2.8e-06 27.6 0.0 4.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SecA_SW PF07516.13 AAAP01002970.1_2 - 2.5e-41 141.9 1.0 2.9e-41 141.7 1.0 1.0 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SEC-C PF02810.15 AAAP01002970.1_2 - 4e-11 42.6 9.8 5.9e-11 42.1 9.8 1.3 1 0 0 1 1 1 1 SEC-C motif GSH-S_ATP PF02955.16 AAAP01002971.1_1 - 5.2e-70 234.4 0.0 7.8e-70 233.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AAAP01002971.1_1 - 1.4e-40 138.1 0.4 2.4e-40 137.4 0.4 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AAAP01002971.1_1 - 6.2e-15 55.3 0.0 1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAAP01002971.1_1 - 8.1e-05 22.0 0.0 0.00035 19.9 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp DUF551 PF04448.12 AAAP01002971.1_2 - 0.055 14.4 0.1 0.071 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF551) FAD_binding_3 PF01494.19 AAAP01002971.1_3 - 1.5e-08 34.3 0.3 2e-08 33.9 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 AAAP01002971.1_3 - 0.023 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 AAAP01002971.1_3 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF1581 PF07619.11 AAAP01002971.1_3 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) BCA_ABC_TP_C PF12399.8 AAAP01002972.1_1 - 2.2e-07 30.6 0.0 4.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_25 PF13481.6 AAAP01002972.1_1 - 0.019 14.6 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01002972.1_1 - 0.042 14.4 0.1 0.063 13.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 AAAP01002972.1_1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAAP01002972.1_2 - 1.1e-28 100.5 0.0 1.4e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01002972.1_2 - 3.2e-11 43.6 0.2 7.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01002972.1_2 - 2.5e-05 23.8 0.3 0.0016 17.9 0.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01002972.1_2 - 2.7e-05 24.8 0.1 4.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01002972.1_2 - 0.0012 18.6 0.0 0.0034 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01002972.1_2 - 0.0017 18.0 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01002972.1_2 - 0.0035 17.6 0.1 0.038 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01002972.1_2 - 0.0086 16.1 0.0 0.015 15.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AAAP01002972.1_2 - 0.0088 16.4 0.1 0.013 15.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01002972.1_2 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AAAP01002972.1_2 - 0.012 15.3 1.0 0.029 14.1 1.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01002972.1_2 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAAP01002972.1_2 - 0.035 12.8 0.0 0.059 12.0 0.0 1.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AAAP01002972.1_2 - 0.036 12.9 1.4 0.13 11.0 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class TniB PF05621.11 AAAP01002972.1_2 - 0.039 13.4 0.1 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein DUF3584 PF12128.8 AAAP01002972.1_2 - 0.041 11.4 0.1 0.054 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_28 PF13521.6 AAAP01002972.1_2 - 0.066 13.5 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01002972.1_2 - 0.067 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DLIC PF05783.11 AAAP01002972.1_2 - 0.069 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 AAAP01002972.1_2 - 0.095 13.1 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AAAP01002972.1_2 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 AAAP01002972.1_2 - 0.16 12.3 0.2 1.3 9.3 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 AAAP01002972.1_2 - 0.17 11.5 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF1501 PF07394.12 AAAP01002973.1_1 - 8.9e-33 113.9 0.4 1e-32 113.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) HTH_1 PF00126.27 AAAP01002973.1_3 - 1.8e-10 40.6 1.4 2.1e-10 40.4 1.4 1.1 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Cro PF09048.10 AAAP01002973.1_3 - 0.067 13.2 0.1 0.074 13.1 0.1 1.2 1 0 0 1 1 1 0 Cro Porin_2 PF02530.14 AAAP01002974.1_1 - 5.4e-15 55.5 7.1 1.2e-14 54.4 7.1 1.5 1 1 0 1 1 1 1 Porin subfamily Porin_2 PF02530.14 AAAP01002974.1_2 - 9.3e-11 41.6 1.6 1e-10 41.5 1.6 1.0 1 0 0 1 1 1 1 Porin subfamily DUF5516 PF17637.2 AAAP01002975.1_1 - 0.043 13.6 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5516) YIF1 PF03878.15 AAAP01002975.1_1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 YIF1 FlgH PF02107.16 AAAP01002975.1_2 - 4.9e-57 192.2 1.5 5.7e-57 192.0 1.5 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein ChapFlgA PF13144.6 AAAP01002975.1_3 - 3.2e-20 72.4 0.2 3.8e-20 72.2 0.2 1.0 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation DoxX_2 PF13564.6 AAAP01002976.1_1 - 0.00068 19.7 0.5 0.001 19.2 0.5 1.3 1 1 0 1 1 1 1 DoxX-like family Radical_SAM PF04055.21 AAAP01002976.1_3 - 4.4e-24 85.7 0.0 1.4e-23 84.1 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 AAAP01002976.1_3 - 4.9e-21 74.6 0.0 7.5e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 CLP1_P PF16575.5 AAAP01002976.1_3 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CHAD PF05235.14 AAAP01002977.1_1 - 5.7e-38 131.1 18.8 1e-37 130.3 18.8 1.4 1 0 0 1 1 1 1 CHAD domain CYTH PF01928.21 AAAP01002977.1_1 - 3.6e-23 82.4 0.4 6.4e-23 81.6 0.1 1.6 2 0 0 2 2 2 1 CYTH domain THDPS_M PF14789.6 AAAP01002977.1_1 - 0.58 10.3 2.0 19 5.4 0.0 3.3 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase middle Pkinase PF00069.25 AAAP01002977.1_2 - 4.9e-09 35.9 0.0 1.8e-07 30.8 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAAP01002977.1_2 - 3.4e-06 26.6 0.0 0.00034 20.0 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 AAAP01002977.1_2 - 1.6e-05 24.3 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AAAP01002977.1_2 - 0.00014 21.9 0.3 0.00022 21.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AAAP01002977.1_2 - 0.064 12.6 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like SBP_bac_5 PF00496.22 AAAP01002978.1_2 - 2.7e-33 115.5 0.0 3.7e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SIR2_2 PF13289.6 AAAP01002979.1_1 - 0.00019 21.5 0.0 0.0003 20.9 0.0 1.2 1 0 0 1 1 1 1 SIR2-like domain DsbD PF02683.15 AAAP01002980.1_2 - 0.016 15.1 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Ferritin PF00210.24 AAAP01002981.1_2 - 6.7e-29 100.6 0.5 7.6e-29 100.5 0.5 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AAAP01002981.1_2 - 4.9e-05 23.7 0.1 0.002 18.5 0.1 2.1 2 0 0 2 2 2 1 Rubrerythrin Ferritin_2 PF13668.6 AAAP01002981.1_2 - 0.0033 17.6 0.1 0.0043 17.2 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain SpoU_methylas_C PF12105.8 AAAP01002981.1_2 - 0.13 12.0 0.0 28 4.5 0.0 3.0 2 1 1 3 3 3 0 SpoU, rRNA methylase, C-terminal PMSR PF01625.21 AAAP01002981.1_3 - 1.3e-53 181.3 0.1 1.5e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SelR PF01641.18 AAAP01002981.1_5 - 4.5e-50 168.8 0.0 5.1e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AAAP01002981.1_5 - 0.029 14.6 0.0 0.049 13.8 0.0 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 AAAP01002981.1_5 - 0.03 13.2 0.0 0.57 9.0 0.0 1.9 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-Mss51 PF13824.6 AAAP01002981.1_5 - 0.1 12.7 0.4 1.5 9.0 0.0 2.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Glycos_transf_N PF04413.16 AAAP01002983.1_1 - 1.9e-47 161.2 0.0 8.2e-47 159.1 0.0 1.8 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glyco_trans_4_4 PF13579.6 AAAP01002983.1_1 - 4e-07 30.6 5.6 4e-07 30.6 5.6 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain LpxK PF02606.14 AAAP01002983.1_2 - 5e-52 177.0 0.1 5.8e-52 176.8 0.1 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Transposase_mut PF00872.18 AAAP01002984.1_1 - 5.2e-06 25.6 0.0 6e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family DnaB_bind PF10410.9 AAAP01002984.1_1 - 0.054 13.7 0.1 8.4 6.7 0.0 2.9 3 1 0 3 3 3 0 DnaB-helicase binding domain of primase FecCD PF01032.18 AAAP01002984.1_2 - 1.1e-23 83.7 7.7 1.4e-23 83.4 7.7 1.0 1 0 0 1 1 1 1 FecCD transport family Peripla_BP_2 PF01497.18 AAAP01002984.1_3 - 0.038 13.5 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein ILVD_EDD PF00920.21 AAAP01002985.1_1 - 1.9e-123 412.8 0.1 2.4e-123 412.5 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family EutC PF05985.11 AAAP01002985.1_2 - 2.9e-32 111.9 0.0 3.4e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) Methyltransf_11 PF08241.12 AAAP01002986.1_1 - 1.4e-24 86.5 0.0 2.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01002986.1_1 - 1.2e-23 83.7 0.0 2.6e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01002986.1_1 - 8.8e-18 64.5 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AAAP01002986.1_1 - 1.4e-17 63.9 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01002986.1_1 - 2e-16 60.2 0.0 2.9e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01002986.1_1 - 6.4e-13 49.3 0.0 1.1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01002986.1_1 - 6.8e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 AAAP01002986.1_1 - 0.00026 20.2 0.0 0.00051 19.2 0.0 1.4 2 0 0 2 2 2 1 DREV methyltransferase MetW PF07021.12 AAAP01002986.1_1 - 0.0024 17.5 0.0 0.0053 16.4 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.11 AAAP01002986.1_1 - 0.0054 15.8 0.0 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 AAAP01002986.1_1 - 0.0064 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 AAAP01002986.1_1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AAAP01002986.1_1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 AAAP01002986.1_1 - 0.023 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 AAAP01002986.1_1 - 0.042 12.9 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 AAAP01002986.1_1 - 0.067 12.9 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 AAAP01002986.1_1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.11 AAAP01002986.1_1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 AAAP01002986.1_1 - 0.17 11.1 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_7 PF03492.15 AAAP01002986.1_1 - 0.2 10.8 0.0 3.9 6.6 0.0 2.0 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase MFS_1 PF07690.16 AAAP01002986.1_2 - 4.7e-18 65.2 44.8 5.6e-09 35.4 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF898 PF05987.13 AAAP01002986.1_2 - 0.051 12.6 16.5 0.073 12.1 16.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Sugar_tr PF00083.24 AAAP01002986.1_2 - 0.074 11.9 22.5 0.5 9.2 0.6 2.1 2 0 0 2 2 2 0 Sugar (and other) transporter Trp_oprn_chp PF09534.10 AAAP01002986.1_2 - 2.9 7.7 16.3 3.5 7.4 0.7 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA_22 PF13401.6 AAAP01002987.1_1 - 3.7e-08 33.7 0.0 5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 AAAP01002987.1_1 - 0.00022 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_14 PF13173.6 AAAP01002987.1_1 - 0.049 13.7 0.2 6.6 6.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain rve PF00665.26 AAAP01002987.1_2 - 1.1e-08 35.3 0.0 2.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AAAP01002987.1_2 - 0.0063 16.4 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Mu transposase, C-terminal ALGX PF16822.5 AAAP01002988.1_1 - 6.8e-10 39.1 0.1 1.3e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX DHHW PF14286.6 AAAP01002988.1_1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 DHHW protein Virul_fac_BrkB PF03631.15 AAAP01002988.1_2 - 2.4e-44 151.9 26.7 2.9e-44 151.6 26.7 1.0 1 0 0 1 1 1 1 Virulence factor BrkB EamA PF00892.20 AAAP01002988.1_3 - 0.00023 21.4 6.9 0.00029 21.0 6.9 1.1 1 0 0 1 1 1 1 EamA-like transporter family GMC_oxred_N PF00732.19 AAAP01002989.1_1 - 1.3e-13 51.0 0.0 8e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 AAAP01002989.1_1 - 5.1e-10 39.0 0.7 0.00052 19.2 0.1 2.5 2 1 1 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01002989.1_1 - 1.6e-07 30.9 0.0 6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01002989.1_1 - 3.4e-07 29.7 0.0 0.0068 15.5 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01002989.1_1 - 2.5e-06 27.1 0.8 0.00043 19.7 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 AAAP01002989.1_1 - 4.8e-06 26.4 0.0 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01002989.1_1 - 7.5e-06 26.1 0.1 2.1e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AAAP01002989.1_1 - 0.00044 19.6 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAAP01002989.1_1 - 0.00081 18.2 0.0 0.0096 14.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 AAAP01002989.1_1 - 0.0024 17.0 0.1 0.0051 15.9 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 AAAP01002989.1_1 - 0.0056 15.9 0.0 0.03 13.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 AAAP01002989.1_1 - 0.027 13.7 0.0 0.052 12.8 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01002989.1_1 - 0.036 14.6 0.0 1.3 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAAP01002989.1_1 - 0.039 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 AAAP01002989.1_1 - 0.19 10.9 0.0 16 4.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DoxX PF07681.12 AAAP01002989.1_2 - 8.2e-08 32.7 6.6 1.4e-07 32.0 6.6 1.4 1 0 0 1 1 1 1 DoxX SURF4 PF02077.15 AAAP01002989.1_2 - 0.011 15.3 2.6 0.043 13.4 2.6 1.8 1 1 0 1 1 1 0 SURF4 family CorC_HlyC PF03471.17 AAAP01002991.1_1 - 7.4e-20 70.7 0.0 6.3e-19 67.8 0.0 2.4 2 1 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AAAP01002991.1_1 - 1.2e-13 51.2 0.3 5.5e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain MarR PF01047.22 AAAP01002991.1_2 - 1.5e-14 53.6 0.0 2.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01002991.1_2 - 4.7e-10 39.2 0.6 8.4e-10 38.4 0.1 1.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAAP01002991.1_2 - 1.5e-06 28.6 0.0 3.3e-06 27.5 0.0 1.6 2 0 0 2 2 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAAP01002991.1_2 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AAAP01002991.1_2 - 0.0089 16.1 1.1 0.071 13.2 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 AAAP01002991.1_2 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AAAP01002991.1_2 - 0.025 14.4 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_34 PF13601.6 AAAP01002991.1_2 - 0.049 13.8 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 AAAP01002991.1_2 - 0.066 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF4194 PF13835.6 AAAP01002991.1_2 - 0.076 12.8 0.3 0.94 9.2 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4194) FeoC PF09012.10 AAAP01002991.1_2 - 0.092 12.8 0.1 0.38 10.9 0.0 2.1 2 1 0 2 2 2 0 FeoC like transcriptional regulator Penicillinase_R PF03965.16 AAAP01002991.1_2 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor HTH_38 PF13936.6 AAAP01002991.1_2 - 0.15 11.8 0.0 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Proteasome PF00227.26 AAAP01002992.1_2 - 1.5e-17 63.7 0.7 4e-17 62.3 0.7 1.6 1 1 0 1 1 1 1 Proteasome subunit AAA_2 PF07724.14 AAAP01002992.1_3 - 7.9e-37 127.0 0.0 3.1e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAAP01002992.1_3 - 1.5e-14 54.6 0.1 8.2e-07 29.5 0.1 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01002992.1_3 - 3.6e-08 33.5 0.5 6.8e-06 26.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAAP01002992.1_3 - 8.7e-06 25.3 0.2 0.0012 18.3 0.0 3.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAAP01002992.1_3 - 4.5e-05 23.7 0.1 0.00019 21.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 AAAP01002992.1_3 - 5.3e-05 23.7 0.3 0.00012 22.5 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 AAAP01002992.1_3 - 0.00011 21.4 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain AAA_28 PF13521.6 AAAP01002992.1_3 - 0.0011 19.3 0.9 0.0015 18.8 0.1 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 AAAP01002992.1_3 - 0.0015 18.7 0.1 0.0033 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 AAAP01002992.1_3 - 0.0017 17.6 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Sigma54_activat PF00158.26 AAAP01002992.1_3 - 0.0019 17.9 0.2 0.23 11.2 0.0 2.5 3 0 0 3 3 2 1 Sigma-54 interaction domain TIP49 PF06068.13 AAAP01002992.1_3 - 0.0025 17.1 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 AAAP01002992.1_3 - 0.0032 18.0 0.0 0.0062 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AAAP01002992.1_3 - 0.0059 16.4 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATP-synt_ab PF00006.25 AAAP01002992.1_3 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 AAAP01002992.1_3 - 0.0074 15.9 0.3 2.7 7.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 AAAP01002992.1_3 - 0.016 15.7 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 AAAP01002992.1_3 - 0.018 14.3 0.0 0.03 13.6 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin TniB PF05621.11 AAAP01002992.1_3 - 0.019 14.4 0.4 0.076 12.4 0.0 2.1 3 1 1 4 4 4 0 Bacterial TniB protein PduV-EutP PF10662.9 AAAP01002992.1_3 - 0.032 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 AAAP01002992.1_3 - 0.037 13.9 0.1 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 AAAP01002992.1_3 - 0.043 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 AAAP01002992.1_3 - 0.058 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 AAAP01002992.1_3 - 0.08 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Rad17 PF03215.15 AAAP01002992.1_3 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 AAAP01002992.1_3 - 0.1 12.6 0.1 13 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAAP01002992.1_3 - 0.12 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AAAP01002992.1_3 - 0.2 12.1 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DHH PF01368.20 AAAP01002993.1_2 - 0.082 13.2 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 DHH family RrnaAD PF00398.20 AAAP01002994.1_1 - 5.3e-37 127.3 0.0 6.4e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AAAP01002994.1_1 - 0.0014 19.2 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01002994.1_1 - 0.088 13.5 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 AAAP01002994.1_2 - 1.6e-19 70.6 0.1 4.2e-19 69.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01002994.1_2 - 5.1e-17 63.2 12.8 5.1e-17 63.2 12.8 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01002994.1_2 - 1.8e-13 50.3 0.9 1.8e-13 50.3 0.9 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 AAAP01002994.1_2 - 0.00035 19.7 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) RibD_C PF01872.17 AAAP01002994.1_2 - 0.019 14.8 0.2 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Abhydrolase_2 PF02230.16 AAAP01002994.1_2 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Mur_ligase_M PF08245.12 AAAP01002995.1_1 - 3.9e-14 53.1 0.0 5.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain HATPase_c PF02518.26 AAAP01002996.1_1 - 2.7e-22 79.4 0.0 3.2e-21 75.9 0.0 2.3 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01002996.1_1 - 3.5e-06 27.0 0.0 7.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01002996.1_1 - 4.6e-06 26.5 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01002996.1_1 - 5.5e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 GHKL domain SopD PF11047.8 AAAP01002996.1_1 - 0.065 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Salmonella outer protein D COX1 PF00115.20 AAAP01002997.1_1 - 1.1e-11 44.3 3.4 1.2e-11 44.1 3.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 AAAP01002997.1_2 - 1.9e-16 60.1 0.3 3.4e-15 56.0 0.0 2.2 1 1 1 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain Cytochrome_CBB3 PF13442.6 AAAP01002997.1_2 - 2.9e-07 30.7 0.0 5.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01002997.1_2 - 2.2e-06 28.7 0.0 5e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c Cupredoxin_1 PF13473.6 AAAP01002997.1_2 - 2.9e-05 24.1 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain COX2_TM PF02790.15 AAAP01002997.1_2 - 0.00075 19.6 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Uroplakin_II PF07353.12 AAAP01002997.1_2 - 0.012 15.2 0.2 1.4 8.3 0.4 2.1 2 0 0 2 2 2 0 Uroplakin II DUF1418 PF07214.12 AAAP01002997.1_2 - 0.038 13.8 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) RDD PF06271.12 AAAP01002997.1_2 - 0.059 13.6 0.7 0.1 12.8 0.7 1.3 1 0 0 1 1 1 0 RDD family GntR PF00392.21 AAAP01002997.1_3 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_18 PF12833.7 AAAP01002998.1_1 - 6e-22 77.7 0.1 6e-22 77.7 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01002998.1_1 - 2.9e-13 49.5 0.0 3.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 AAAP01002998.1_1 - 0.0085 15.9 0.2 0.44 10.4 0.2 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 AAAP01002998.1_1 - 0.044 14.1 0.0 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Transposase Trns_repr_metal PF02583.17 AAAP01002998.1_2 - 2e-20 73.0 0.7 2.2e-20 72.8 0.7 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor Pentapeptide PF00805.22 AAAP01002999.1_1 - 6.5e-25 86.4 8.3 7.5e-11 41.5 0.6 4.3 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AAAP01002999.1_1 - 6.2e-12 45.5 0.1 0.00025 21.1 0.0 3.7 2 2 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 AAAP01002999.1_1 - 2.4e-08 34.0 0.0 7.8e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) cNMP_binding PF00027.29 AAAP01002999.1_3 - 0.00055 19.9 0.0 0.00076 19.5 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FAD_binding_7 PF03441.14 AAAP01003000.1_1 - 0.0068 15.9 1.8 0.013 15.0 1.8 1.6 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase GyrI-like PF06445.15 AAAP01003000.1_2 - 3.6e-15 56.6 0.0 4.8e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Antimicrobial_4 PF08024.11 AAAP01003000.1_2 - 0.14 12.2 0.4 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 Ant antimicrobial peptide Transgly PF00912.22 AAAP01003000.1_3 - 2.8e-45 154.0 0.0 3.9e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase RskA PF10099.9 AAAP01003000.1_3 - 0.35 11.1 6.0 0.052 13.8 1.9 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Condensation PF00668.20 AAAP01003001.1_1 - 9.5e-63 212.4 0.0 1.3e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.15 AAAP01003001.1_1 - 0.26 9.9 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Transferase family PP-binding PF00550.25 AAAP01003001.1_2 - 5.6e-12 45.8 0.4 6.7e-12 45.6 0.4 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Queuosine_synth PF02547.15 AAAP01003002.1_1 - 1.1e-05 24.8 0.2 1.1e-05 24.8 0.2 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein DUF4111 PF13427.6 AAAP01003002.1_2 - 4.9e-10 39.5 0.1 8.4e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) NTP_transf_2 PF01909.23 AAAP01003002.1_2 - 2.5e-05 24.5 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAAP01003002.1_2 - 0.062 13.4 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase TGT PF01702.18 AAAP01003002.1_4 - 1.2e-85 287.8 0.0 1.3e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Cys_rich_FGFR PF00839.17 AAAP01003002.1_5 - 0.0097 16.1 0.3 0.17 12.1 0.1 2.0 2 0 0 2 2 2 2 Cysteine rich repeat Flavi_M PF01004.19 AAAP01003003.1_1 - 5.2 6.9 6.9 3.3 7.5 3.1 2.6 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M LeuA_dimer PF08502.10 AAAP01003004.1_1 - 6.7e-08 32.5 0.0 8e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain ILVD_EDD PF00920.21 AAAP01003004.1_2 - 2.5e-91 306.8 1.4 3e-91 306.6 1.4 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_S27 PF01599.19 AAAP01003004.1_2 - 0.28 11.4 4.5 12 6.2 0.6 3.0 3 0 0 3 3 3 0 Ribosomal protein S27a Hpt PF01627.23 AAAP01003005.1_1 - 1.8e-13 50.6 0.1 1.8e-13 50.6 0.1 3.0 3 0 0 3 3 3 1 Hpt domain H-kinase_dim PF02895.14 AAAP01003005.1_1 - 2.2e-13 50.4 0.7 6.6e-13 48.8 0.7 1.9 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.26 AAAP01003005.1_1 - 5.1e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01003005.1_1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CutA1 PF03091.15 AAAP01003006.1_2 - 9.7e-30 102.4 0.0 1.1e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein NAD_kinase PF01513.21 AAAP01003006.1_3 - 9.1e-20 71.0 0.0 1.6e-19 70.2 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAAP01003006.1_3 - 0.00035 20.2 0.0 0.00063 19.4 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Prenyltransf PF01255.19 AAAP01003007.1_1 - 1.1e-26 93.8 0.0 1.2e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RRF PF01765.19 AAAP01003007.1_2 - 3.7e-60 202.6 0.4 4.2e-60 202.4 0.4 1.0 1 0 0 1 1 1 1 Ribosome recycling factor DUF1320 PF07030.12 AAAP01003007.1_2 - 0.14 12.2 1.0 0.27 11.4 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1320) Rick_17kDa_Anti PF05433.15 AAAP01003007.1_3 - 0.052 13.4 12.2 0.23 11.4 11.0 2.3 1 1 2 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AAAP01003007.1_3 - 0.92 9.6 14.9 0.89 9.6 4.0 2.7 3 0 0 3 3 3 0 Glycine zipper FAD_binding_3 PF01494.19 AAAP01003007.1_4 - 4.8e-09 35.9 0.5 5.7e-09 35.7 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 AAAP01003007.1_4 - 0.0023 17.0 0.0 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Hydantoinase_B PF02538.14 AAAP01003008.1_1 - 5.7e-25 87.7 0.0 6.9e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 AAAP01003008.1_2 - 5.8e-65 219.4 0.5 7.3e-65 219.1 0.5 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase HTH_AsnC-type PF13404.6 AAAP01003008.1_2 - 0.045 13.6 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain Ppx-GppA PF02541.16 AAAP01003008.1_2 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family MutL PF13941.6 AAAP01003008.1_2 - 0.18 10.4 0.1 0.18 10.4 0.1 1.4 2 0 0 2 2 2 0 MutL protein MotA_ExbB PF01618.16 AAAP01003009.1_1 - 4.8e-07 29.6 2.1 4.8e-07 29.6 2.1 2.3 2 1 0 2 2 2 1 MotA/TolQ/ExbB proton channel family SHR3_chaperone PF08229.11 AAAP01003009.1_1 - 0.1 11.6 0.0 3.4 6.6 0.0 2.5 2 0 0 2 2 2 0 ER membrane protein SH3 DUF485 PF04341.12 AAAP01003009.1_1 - 0.39 10.7 3.9 0.99 9.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PilA4 PF18682.1 AAAP01003009.1_2 - 0.0083 16.5 0.6 0.012 16.0 0.6 1.2 1 0 0 1 1 1 1 Pilin A4 SlyX PF04102.12 AAAP01003009.1_2 - 2.3 8.9 7.3 1.3 9.7 0.7 2.4 1 1 1 2 2 2 0 SlyX Bact_transglu_N PF08379.10 AAAP01003010.1_1 - 9e-22 77.8 0.0 1.7e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAAP01003010.1_1 - 2e-15 57.2 0.0 3.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAAP01003010.1_1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain Alpha-E PF04168.12 AAAP01003010.1_2 - 3.2e-20 73.1 1.9 1.3e-12 48.1 0.0 2.0 2 0 0 2 2 2 2 A predicted alpha-helical domain with a conserved ER motif. DAGK_cat PF00781.24 AAAP01003011.1_1 - 5.6e-22 77.7 0.1 6.3e-22 77.5 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AAAP01003011.1_1 - 0.00011 21.5 0.1 0.00012 21.4 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Peripla_BP_6 PF13458.6 AAAP01003011.1_1 - 0.06 13.0 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF4228 PF14009.6 AAAP01003011.1_2 - 4.4 7.7 11.7 13 6.1 11.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) FliP PF00813.20 AAAP01003012.1_1 - 2.2e-14 53.8 5.0 2.3e-14 53.7 5.0 1.0 1 0 0 1 1 1 1 FliP family FliP PF00813.20 AAAP01003012.1_2 - 2.8e-38 131.7 0.0 3.9e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 FliP family adh_short_C2 PF13561.6 AAAP01003012.1_3 - 1.3e-68 231.0 0.0 1.6e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003012.1_3 - 8.8e-13 48.1 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003012.1_3 - 0.055 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 KR domain TetR_C_28 PF17937.1 AAAP01003013.1_1 - 6.3e-16 58.6 1.0 6.3e-16 58.6 1.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAAP01003013.1_1 - 7.1e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Multi_Drug_Res PF00893.19 AAAP01003013.1_2 - 2.1e-21 76.4 6.8 2.8e-21 76.0 6.8 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein TMEM234 PF10639.9 AAAP01003013.1_2 - 0.00021 21.3 2.1 0.00028 20.9 2.1 1.3 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 AAAP01003013.1_2 - 0.00074 19.7 7.7 0.00092 19.4 7.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family UPF0060 PF02694.15 AAAP01003013.1_2 - 0.0027 17.9 6.1 0.0035 17.6 6.1 1.2 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family MFS_MOT1 PF16983.5 AAAP01003013.1_2 - 0.6 10.5 13.2 0.17 12.3 6.4 2.0 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily DUF2157 PF09925.9 AAAP01003013.1_2 - 5.6 6.7 9.7 1.9 8.2 6.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) TetR_N PF00440.23 AAAP01003013.1_3 - 1.4e-15 56.8 0.1 2.2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MFS_1_like PF12832.7 AAAP01003014.1_1 - 2.2e-26 92.6 8.3 8.4e-26 90.7 8.3 1.8 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AAAP01003014.1_1 - 8.8e-12 44.6 61.0 6.1e-05 22.1 39.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 AAAP01003014.1_1 - 0.00016 20.6 0.1 0.00029 19.7 0.1 1.4 1 0 0 1 1 1 1 LacY proton/sugar symporter Nuc_H_symport PF03825.16 AAAP01003014.1_1 - 0.097 11.6 6.8 0.023 13.7 3.1 1.7 2 0 0 2 2 2 0 Nucleoside H+ symporter Sod_Fe_N PF00081.22 AAAP01003015.1_1 - 1.7e-30 105.3 4.6 2.2e-30 105.0 4.6 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 AAAP01003015.1_1 - 1.1e-12 47.9 0.0 2.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain GHMP_kinases_C PF08544.13 AAAP01003016.1_1 - 3.8e-09 36.8 0.3 9.6e-09 35.5 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AAAP01003016.1_1 - 3.3e-06 27.2 3.3 3.5e-06 27.2 1.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain polyprenyl_synt PF00348.17 AAAP01003016.1_2 - 2.6e-70 236.4 0.0 3.1e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Peripla_BP_6 PF13458.6 AAAP01003017.1_1 - 9.5e-13 48.5 2.5 2.5e-12 47.1 0.4 2.0 2 0 0 2 2 2 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01003017.1_1 - 0.0007 18.8 0.0 0.0014 17.8 0.0 1.4 2 0 0 2 2 2 1 Receptor family ligand binding region DUF1952 PF09189.10 AAAP01003017.1_1 - 0.14 12.0 0.8 11 5.9 0.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1952) AA_kinase PF00696.28 AAAP01003018.1_1 - 1.3e-24 87.1 1.2 1.1e-23 84.1 0.2 2.0 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 AAAP01003018.1_1 - 6.1e-22 77.1 1.7 9e-13 47.8 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 AAAP01003018.1_1 - 7.4e-19 67.3 1.3 8.1e-12 44.8 0.3 2.5 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 AAAP01003018.1_1 - 0.0066 16.4 0.1 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AAAP01003018.1_1 - 0.02 15.5 0.1 3.9 8.1 0.0 2.5 2 0 0 2 2 2 0 ACT domain PEP-utilisers_N PF05524.13 AAAP01003018.1_2 - 2e-23 82.8 0.6 5.1e-23 81.5 0.6 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAAP01003018.1_2 - 3.4e-20 71.5 0.5 6.2e-20 70.7 0.5 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GAF_2 PF13185.6 AAAP01003018.1_2 - 1e-11 45.3 1.4 2.1e-11 44.3 0.0 2.2 4 0 0 4 4 4 1 GAF domain GAF PF01590.26 AAAP01003018.1_2 - 1.1e-09 39.0 0.0 6.3e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAAP01003018.1_2 - 0.056 13.8 0.3 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 GAF domain DegS PF05384.11 AAAP01003018.1_2 - 0.64 9.5 5.6 0.32 10.5 0.9 2.6 3 1 0 3 3 3 0 Sensor protein DegS OsmC PF02566.19 AAAP01003019.1_1 - 1.4e-22 80.0 0.0 1.6e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 OsmC-like protein Acyl-CoA_dh_N PF02771.16 AAAP01003019.1_2 - 0.00019 22.1 0.2 0.00038 21.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PSI_integrin PF17205.3 AAAP01003019.1_2 - 0.13 12.1 0.8 0.26 11.0 0.8 1.4 1 0 0 1 1 1 0 Integrin plexin domain Creatininase PF02633.14 AAAP01003020.1_1 - 4e-48 164.0 0.6 4.5e-48 163.8 0.6 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase IclR PF01614.18 AAAP01003020.1_2 - 1e-21 77.1 0.0 1.5e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 AAAP01003020.1_2 - 1.5e-08 34.3 0.1 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AAAP01003020.1_2 - 0.005 16.7 0.7 0.017 15.0 0.3 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AAAP01003020.1_2 - 0.0062 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DprA_WH PF17782.1 AAAP01003020.1_2 - 0.0071 16.4 0.1 0.036 14.2 0.1 2.2 2 0 0 2 2 2 1 DprA winged helix domain MarR PF01047.22 AAAP01003020.1_2 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 MarR family CTP_transf_1 PF01148.20 AAAP01003021.1_1 - 2e-24 86.8 2.9 2.4e-24 86.5 2.9 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family DXPR_C PF13288.6 AAAP01003021.1_2 - 9.8e-36 122.5 0.0 1.6e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AAAP01003021.1_2 - 8.1e-35 118.9 0.1 1.6e-34 117.9 0.1 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 AAAP01003021.1_2 - 3.3e-33 115.2 2.4 6e-33 114.3 2.4 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 AAAP01003021.1_2 - 0.0019 18.5 0.5 0.0095 16.2 0.5 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 AAAP01003021.1_2 - 0.068 13.6 0.7 0.55 10.7 0.7 2.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 AAAP01003021.1_2 - 0.077 12.5 1.2 0.15 11.6 0.9 1.6 2 0 0 2 2 2 0 NmrA-like family DivIVA PF05103.13 AAAP01003022.1_2 - 0.031 14.4 4.0 0.045 13.8 4.0 1.2 1 0 0 1 1 1 0 DivIVA protein Band_7 PF01145.25 AAAP01003022.1_2 - 0.06 13.3 0.5 0.06 13.3 0.5 1.7 2 0 0 2 2 2 0 SPFH domain / Band 7 family Flot PF15975.5 AAAP01003022.1_2 - 5.2 7.3 8.0 18 5.5 8.0 2.0 1 1 0 1 1 1 0 Flotillin DHFR_1 PF00186.19 AAAP01003022.1_3 - 1.8e-56 190.3 0.0 2.1e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Acetyltransf_3 PF13302.7 AAAP01003023.1_1 - 3e-24 86.3 0.0 3.6e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003023.1_1 - 9e-05 22.7 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GTP1_OBG PF01018.22 AAAP01003023.1_3 - 2.1e-59 199.6 2.4 2.9e-59 199.1 2.4 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AAAP01003023.1_3 - 2.9e-23 82.1 0.0 4.2e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01003023.1_3 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 2 0 0 2 2 2 1 Ferrous iron transport protein B HATPase_c PF02518.26 AAAP01003024.1_1 - 1.5e-23 83.4 0.0 1.7e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01003024.1_1 - 2.5e-05 24.1 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01003024.1_1 - 0.0024 17.7 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldo_ket_red PF00248.21 AAAP01003024.1_2 - 8.8e-26 90.8 0.0 7.4e-23 81.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF772 PF05598.11 AAAP01003025.1_1 - 1.8e-27 95.1 0.1 3.2e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Transposase domain (DUF772) AMP-binding PF00501.28 AAAP01003026.1_1 - 4.7e-22 78.2 0.0 5.6e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Bcr-Abl_Oligo PF09036.10 AAAP01003026.1_1 - 0.098 12.7 0.1 4 7.5 0.0 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain KH_2 PF07650.17 AAAP01003027.1_1 - 5.3e-16 58.2 0.8 7.3e-16 57.8 0.8 1.2 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AAAP01003027.1_1 - 0.00053 19.8 0.2 0.00071 19.4 0.2 1.2 1 0 0 1 1 1 1 KH domain MRP-S24 PF14955.6 AAAP01003027.1_1 - 0.026 14.5 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 KH_1 PF00013.29 AAAP01003027.1_1 - 0.053 13.4 0.5 0.095 12.5 0.3 1.5 1 1 0 1 1 1 0 KH domain Ribosomal_L22 PF00237.19 AAAP01003027.1_2 - 2.5e-31 108.0 0.2 2.9e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3734 PF12536.8 AAAP01003027.1_2 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Patatin phospholipase Ribosomal_S19 PF00203.21 AAAP01003027.1_3 - 1.3e-35 121.1 0.0 1.5e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 AAAP01003027.1_4 - 5.1e-55 185.0 4.5 6.7e-55 184.7 4.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AAAP01003027.1_4 - 1.4e-13 50.6 0.0 3.5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3463 PF11946.8 AAAP01003028.1_1 - 1.6e-59 199.5 0.1 3.2e-59 198.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) Radical_SAM PF04055.21 AAAP01003028.1_1 - 8.3e-16 58.8 0.1 1.6e-15 57.9 0.1 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01003028.1_1 - 9.8e-06 25.9 0.0 6.3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003028.1_1 - 0.00023 21.3 0.5 0.00065 19.8 0.5 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain HMGL-like PF00682.19 AAAP01003028.1_1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 HMGL-like DUF35_N PF12172.8 AAAP01003029.1_1 - 0.52 10.2 5.1 1.2 9.1 5.1 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Gly-zipper_Omp PF13488.6 AAAP01003029.1_2 - 0.0076 16.2 16.0 0.063 13.3 7.1 2.2 1 1 1 2 2 2 2 Glycine zipper Rick_17kDa_Anti PF05433.15 AAAP01003029.1_2 - 0.1 12.5 18.9 0.085 12.7 16.8 2.0 1 1 1 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AAAP01003029.1_2 - 0.13 12.0 18.1 0.39 10.5 6.1 2.1 1 1 1 2 2 2 0 YMGG-like Gly-zipper TraT PF05818.12 AAAP01003029.1_2 - 2.4 7.8 6.6 2.7 7.6 6.6 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Methyltransf_11 PF08241.12 AAAP01003029.1_3 - 8.1e-09 36.0 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003029.1_3 - 2.5e-08 33.9 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003029.1_3 - 1.2e-05 25.1 0.0 2.9e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003029.1_3 - 2.3e-05 25.0 0.0 4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003029.1_3 - 2.7e-05 24.8 0.0 4.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003029.1_3 - 0.051 12.9 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_21 PF13304.6 AAAP01003030.1_1 - 0.031 14.1 0.0 0.032 14.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAAP01003030.1_1 - 0.039 14.5 0.3 0.061 13.8 0.3 1.3 1 0 0 1 1 1 0 ABC transporter ABC_tran PF00005.27 AAAP01003030.1_2 - 2.7e-09 37.6 0.0 3.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 AAAP01003030.1_2 - 0.0029 17.9 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003030.1_2 - 0.0029 17.3 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003030.1_2 - 0.0045 17.4 0.1 0.0047 17.3 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AAAP01003030.1_2 - 0.022 14.5 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 AAAP01003030.1_2 - 0.026 14.1 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01003030.1_2 - 0.027 14.0 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 AAAP01003030.1_2 - 0.038 13.3 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 AIG1 family DUF87 PF01935.17 AAAP01003030.1_2 - 0.05 13.7 0.1 0.057 13.5 0.1 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 AAAP01003030.1_2 - 0.058 13.3 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 AAAP01003030.1_2 - 0.093 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.12 AAAP01003030.1_2 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Mg_chelatase PF01078.21 AAAP01003030.1_2 - 0.16 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAAP01003030.1_2 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 AAAP01003030.1_2 - 0.2 11.6 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SLT PF01464.20 AAAP01003030.1_3 - 9e-20 70.5 0.0 1.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 AAAP01003030.1_3 - 0.16 11.2 0.3 0.21 10.8 0.2 1.3 1 1 0 1 1 1 0 Transglycosylase SLT domain ApbA PF02558.16 AAAP01003031.1_2 - 2e-38 131.4 0.0 2.4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AAAP01003031.1_2 - 0.00032 21.2 0.0 0.00059 20.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 AAAP01003031.1_2 - 0.0069 16.6 1.0 0.025 14.8 1.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01003031.1_2 - 0.096 11.9 0.3 0.16 11.2 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003031.1_2 - 0.17 12.4 0.4 0.37 11.4 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytochrome_CBB3 PF13442.6 AAAP01003032.1_1 - 0.043 14.1 0.3 0.54 10.6 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1924 PF09086.11 AAAP01003032.1_1 - 0.047 14.1 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) CCP_MauG PF03150.14 AAAP01003032.1_1 - 0.06 14.0 0.0 0.079 13.6 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase TAT_signal PF10518.9 AAAP01003032.1_2 - 0.00028 20.6 0.2 0.00058 19.6 0.2 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Metallophos PF00149.28 AAAP01003032.1_2 - 0.0014 19.1 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01003032.1_2 - 0.005 17.1 0.0 0.018 15.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UCR_Fe-S_N PF10399.9 AAAP01003032.1_2 - 0.006 15.9 0.2 0.013 14.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal YbjN PF10722.9 AAAP01003033.1_1 - 2.2e-24 85.9 0.5 2.7e-24 85.6 0.5 1.0 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator GcnA_N PF18229.1 AAAP01003033.1_1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain BMFP PF04380.13 AAAP01003033.1_2 - 7.3e-22 77.6 5.6 8.4e-22 77.4 5.6 1.0 1 0 0 1 1 1 1 Membrane fusogenic activity Phasin PF05597.11 AAAP01003033.1_2 - 1.2e-05 25.3 0.5 1.8e-05 24.8 0.5 1.4 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) TSC22 PF01166.18 AAAP01003033.1_2 - 0.0016 18.7 0.3 0.0026 18.0 0.2 1.4 1 1 0 1 1 1 1 TSC-22/dip/bun family CbiC PF02570.15 AAAP01003033.1_2 - 0.012 15.3 0.3 0.017 14.8 0.2 1.3 1 1 0 1 1 1 0 Precorrin-8X methylmutase DUF3583 PF12126.8 AAAP01003033.1_2 - 0.054 13.0 1.1 0.062 12.8 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DivIC PF04977.15 AAAP01003033.1_2 - 0.075 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Response_reg PF00072.24 AAAP01003033.1_3 - 1e-26 93.3 0.0 1.5e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003033.1_3 - 8.2e-22 77.1 0.1 2e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAAP01003033.1_3 - 0.049 13.5 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 MarR family HAMP PF00672.25 AAAP01003033.1_4 - 0.011 16.1 0.1 0.012 16.0 0.1 1.1 1 0 0 1 1 1 0 HAMP domain PcfJ PF14284.6 AAAP01003034.1_2 - 0.068 13.1 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 PcfJ-like protein Peptidase_M16 PF00675.20 AAAP01003035.1_1 - 2.9e-25 89.0 0.0 4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAAP01003035.1_1 - 1.8e-12 47.7 0.0 2.6e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Phasin_2 PF09361.10 AAAP01003036.1_1 - 1.5e-13 50.8 9.7 2.8e-13 50.0 8.1 1.8 1 1 1 2 2 2 1 Phasin protein Phasin_2 PF09361.10 AAAP01003036.1_2 - 1.5e-05 25.1 0.7 1.5e-05 25.1 0.7 3.3 3 1 0 3 3 3 1 Phasin protein DNA_topoisoIV PF00521.20 AAAP01003037.1_1 - 1.9e-09 37.0 0.2 2.3e-09 36.7 0.2 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TetR_N PF00440.23 AAAP01003037.1_2 - 3e-14 52.5 0.2 5.5e-14 51.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAAP01003037.1_2 - 6.7e-10 39.2 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 AAAP01003037.1_2 - 0.0085 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_19 PF12844.7 AAAP01003037.1_2 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short_C2 PF13561.6 AAAP01003037.1_3 - 8.2e-32 110.6 0.5 1.1e-31 110.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003037.1_3 - 5.5e-25 88.0 0.2 6.8e-25 87.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 AAAP01003038.1_2 - 4.4e-14 52.2 22.5 5.8e-14 51.8 22.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01003038.1_2 - 0.012 14.5 9.3 0.015 14.2 9.3 1.1 1 0 0 1 1 1 0 MFS_1 like family PsbW PF07123.12 AAAP01003038.1_2 - 0.55 10.2 3.7 0.98 9.4 3.0 1.8 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Acyl_transf_3 PF01757.22 AAAP01003039.1_1 - 2.7e-23 82.6 23.1 3.2e-23 82.3 23.1 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF1616 PF07760.11 AAAP01003039.1_1 - 0.17 11.2 3.0 0.32 10.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF1624 PF07786.12 AAAP01003039.1_1 - 0.25 10.9 13.4 0.036 13.6 7.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) AMP-binding PF00501.28 AAAP01003040.1_1 - 7.1e-34 117.1 0.0 9e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HATPase_c PF02518.26 AAAP01003040.1_2 - 1.2e-26 93.4 0.0 2.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003040.1_2 - 4.2e-14 52.3 0.0 4.2e-14 52.3 0.0 2.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003040.1_2 - 9.5e-12 45.1 1.0 9.5e-12 45.1 1.0 2.9 3 0 0 3 3 3 1 HAMP domain Nup54 PF13874.6 AAAP01003040.1_2 - 0.027 14.6 1.6 0.027 14.6 1.6 1.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF883 PF05957.13 AAAP01003040.1_2 - 0.028 15.0 1.3 0.13 12.9 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HPTransfase PF10090.9 AAAP01003040.1_2 - 0.047 13.5 0.0 0.86 9.4 0.0 2.4 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain Baculo_PEP_C PF04513.12 AAAP01003040.1_2 - 0.087 12.9 0.9 0.52 10.4 0.2 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4530 PF15039.6 AAAP01003040.1_2 - 0.098 12.8 0.2 0.4 10.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) LysR_substrate PF03466.20 AAAP01003041.1_1 - 2.9e-39 134.6 5.1 3.4e-39 134.4 5.1 1.0 1 0 0 1 1 1 1 LysR substrate binding domain Pmp3 PF01679.17 AAAP01003041.1_2 - 6.7e-16 58.2 10.5 7.2e-16 58.1 10.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Cep57_CLD_2 PF14197.6 AAAP01003041.1_3 - 0.41 10.8 6.3 2.3 8.4 3.3 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 3HCDH PF00725.22 AAAP01003041.1_4 - 8.5e-16 58.4 0.0 5.6e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ribosomal_L10 PF00466.20 AAAP01003042.1_1 - 2.3e-24 85.4 0.1 3.2e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Porin_O_P PF07396.11 AAAP01003042.1_2 - 2.7e-13 49.9 0.0 3.1e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Phosphate-selective porin O and P Ribosomal_L9_N PF01281.19 AAAP01003043.1_1 - 5.5e-21 73.9 1.2 7.7e-21 73.4 0.2 1.8 3 0 0 3 3 3 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 AAAP01003043.1_1 - 1.6e-19 70.1 0.0 2.8e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain DUF2232 PF09991.9 AAAP01003043.1_2 - 1.7e-09 37.3 15.9 1.2e-08 34.6 15.9 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) ACR_tran PF00873.19 AAAP01003044.1_1 - 1.3e-25 89.4 10.0 2.2e-25 88.6 10.0 1.3 1 1 0 1 1 1 1 AcrB/AcrD/AcrF family DUF411 PF04214.13 AAAP01003044.1_2 - 2.4e-31 107.5 1.7 2.4e-31 107.5 1.7 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF DAP_epimerase PF01678.19 AAAP01003044.1_3 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Diaminopimelate epimerase Fer2_2 PF01799.20 AAAP01003045.1_1 - 1.3e-30 105.2 3.9 1.4e-30 105.1 0.7 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003045.1_1 - 4e-08 33.1 0.6 4e-08 33.1 0.6 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01003045.1_1 - 7.2e-05 22.8 0.1 0.00014 21.8 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAAP01003045.1_1 - 0.071 13.2 0.6 0.37 10.9 0.6 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FAD_binding_5 PF00941.21 AAAP01003045.1_2 - 9.9e-18 64.4 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase DUF305 PF03713.13 AAAP01003046.1_1 - 1e-19 71.2 1.6 1.2e-19 71.0 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 AAAP01003046.1_1 - 4.8e-05 23.6 0.8 0.00016 22.0 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) TPR_1 PF00515.28 AAAP01003046.1_2 - 0.15 12.0 0.1 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF326 PF03860.16 AAAP01003046.1_2 - 0.38 10.8 44.7 0.24 11.4 11.0 4.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF326) DUF305 PF03713.13 AAAP01003046.1_3 - 1.5e-13 51.2 14.7 2.2e-13 50.6 14.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 AAAP01003046.1_3 - 0.0046 17.2 2.7 0.015 15.5 0.1 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4142) FKBP_N PF01346.18 AAAP01003046.1_3 - 1.2 10.1 8.7 2.6 9.1 0.3 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YHS PF04945.13 AAAP01003046.1_4 - 0.00086 19.4 0.2 0.0013 18.8 0.2 1.3 1 0 0 1 1 1 1 YHS domain ABC_tran PF00005.27 AAAP01003047.1_1 - 2.6e-08 34.5 0.1 3e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01003047.1_1 - 8.9e-05 22.2 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003047.1_1 - 0.0012 19.4 0.1 0.0012 19.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003047.1_1 - 0.0023 17.4 0.1 0.0023 17.4 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01003047.1_1 - 0.0047 16.8 0.0 0.0049 16.8 0.0 1.0 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AAAP01003047.1_1 - 0.015 15.2 0.4 0.019 14.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 AAAP01003047.1_1 - 0.016 14.8 0.1 0.019 14.5 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAAP01003047.1_1 - 0.02 13.6 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003047.1_1 - 0.066 13.4 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003047.1_1 - 0.076 13.4 0.0 0.08 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 AAAP01003047.1_1 - 0.1 12.2 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003047.1_1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAAP01003047.1_1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 AAAP01003047.1_1 - 0.14 11.6 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region UPF0051 PF01458.17 AAAP01003047.1_2 - 3e-66 223.2 0.1 3.7e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) CHIPS PF11434.8 AAAP01003047.1_2 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS IER PF05760.12 AAAP01003047.1_2 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Aminotran_5 PF00266.19 AAAP01003047.1_3 - 6e-07 28.7 0.0 6.9e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PAS_9 PF13426.7 AAAP01003048.1_1 - 5.8e-21 74.7 0.0 2.3e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 PAS domain HATPase_c PF02518.26 AAAP01003048.1_1 - 4.4e-19 69.0 0.1 7.6e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01003048.1_1 - 8.7e-10 38.6 0.0 4e-09 36.5 0.0 2.1 2 1 1 3 3 3 1 PAS fold PAS_3 PF08447.12 AAAP01003048.1_1 - 3e-09 37.0 0.0 6.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003048.1_1 - 2.5e-08 33.8 0.2 4.9e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003048.1_1 - 4.1e-07 30.2 0.1 1.4e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003048.1_1 - 2.8e-06 27.2 0.0 9.6e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AAAP01003048.1_1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003048.1_1 - 0.003 17.5 0.0 0.0064 16.4 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HPTransfase PF10090.9 AAAP01003048.1_1 - 0.003 17.4 0.0 0.0095 15.7 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain SPOB_a PF14689.6 AAAP01003048.1_1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain META PF03724.16 AAAP01003048.1_1 - 0.089 12.8 0.3 0.38 10.7 0.2 2.0 2 0 0 2 2 2 0 META domain HisKA_4TM PF16926.5 AAAP01003048.1_1 - 0.14 11.7 0.3 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase HATPase_c_5 PF14501.6 AAAP01003048.1_1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 GHKL domain Pyr_redox_2 PF07992.14 AAAP01003049.1_1 - 3.2e-38 131.7 0.5 4e-38 131.3 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 AAAP01003049.1_1 - 9.5e-15 54.9 0.0 3.8e-14 53.0 0.0 2.1 2 0 0 2 2 1 1 Reductase C-terminal Pyr_redox PF00070.27 AAAP01003049.1_1 - 5.6e-14 52.5 0.6 1.1e-13 51.6 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003049.1_1 - 6.2e-07 29.3 1.8 3.5e-05 23.6 0.2 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 AAAP01003049.1_1 - 2.5e-06 26.8 0.2 0.059 12.5 0.8 3.0 2 1 1 3 3 3 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 AAAP01003049.1_1 - 2.2e-05 23.5 4.2 0.014 14.3 0.2 2.9 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 AAAP01003049.1_1 - 5.5e-05 23.2 1.1 0.35 10.9 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AAAP01003049.1_1 - 0.00045 20.4 0.4 0.0017 18.5 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AAAP01003049.1_1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 AAAP01003049.1_1 - 0.0012 18.2 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003049.1_1 - 0.0028 17.0 0.2 0.0059 15.9 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AAAP01003049.1_1 - 0.0046 16.1 0.3 0.0092 15.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAAP01003049.1_1 - 0.0049 15.6 1.6 0.15 10.7 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 AAAP01003049.1_1 - 0.0086 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAAP01003049.1_1 - 0.019 14.0 0.6 26 3.7 0.0 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein DUF1344 PF07076.11 AAAP01003049.1_1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) UDPG_MGDP_dh_N PF03721.14 AAAP01003049.1_1 - 0.035 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 AAAP01003049.1_1 - 0.036 14.5 1.9 0.046 14.2 0.2 1.8 1 1 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 AAAP01003049.1_1 - 0.046 13.4 0.2 0.087 12.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAAP01003049.1_1 - 0.083 12.8 0.3 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2235 PF09994.9 AAAP01003050.1_2 - 3.7e-73 246.4 0.0 4.6e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PBP_N PF17093.5 AAAP01003050.1_3 - 0.0021 18.3 0.3 0.003 17.8 0.3 1.3 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus RskA PF10099.9 AAAP01003050.1_3 - 0.0026 18.1 9.0 0.003 17.9 9.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CwsA PF10814.8 AAAP01003050.1_3 - 0.048 13.8 1.2 0.048 13.8 1.2 2.0 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA Endotoxin_C2 PF18449.1 AAAP01003050.1_3 - 0.081 13.3 0.4 0.2 12.0 0.1 1.7 1 1 0 1 1 1 0 Delta endotoxin Cys_Met_Meta_PP PF01053.20 AAAP01003051.1_2 - 1.3e-54 185.2 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Formyl_trans_N PF00551.19 AAAP01003051.1_3 - 7.3e-21 74.7 0.1 9.2e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase adh_short PF00106.25 AAAP01003051.1_4 - 1.4e-21 76.9 0.0 1.7e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003051.1_4 - 5.8e-15 55.5 0.0 7.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 AAAP01003052.1_1 - 1.7e-45 155.5 0.1 2.1e-45 155.2 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003052.1_1 - 9.9e-12 45.3 0.8 5.3e-11 42.9 0.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003052.1_1 - 8.2e-06 25.6 1.5 0.026 14.1 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003052.1_1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 AAAP01003052.1_1 - 0.086 12.8 0.2 0.38 10.7 0.1 1.9 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 AAAP01003052.1_1 - 0.088 12.7 0.6 0.29 11.0 0.5 1.9 1 1 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 AAAP01003052.1_1 - 0.1 12.3 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA EthD PF07110.11 AAAP01003052.1_2 - 1.5e-05 26.0 0.0 2.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 EthD domain Peripla_BP_2 PF01497.18 AAAP01003053.1_1 - 1.4e-20 73.9 0.0 2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 AAAP01003053.1_2 - 4.4e-30 105.0 0.0 5.6e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003053.1_2 - 7.3e-11 42.4 0.4 7.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003053.1_2 - 1.3e-08 34.5 0.0 0.0017 17.9 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAAP01003053.1_2 - 3.6e-06 26.9 0.0 1.7e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 AAAP01003053.1_2 - 8.5e-06 24.8 0.0 0.00021 20.2 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 AAAP01003053.1_2 - 1.8e-05 24.4 0.1 3.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003053.1_2 - 0.00013 22.4 0.9 0.0003 21.2 0.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 AAAP01003053.1_2 - 0.00022 20.9 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAAP01003053.1_2 - 0.00037 21.1 0.0 0.00051 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2813 PF11398.8 AAAP01003053.1_2 - 0.0026 17.1 0.1 0.0068 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_28 PF13521.6 AAAP01003053.1_2 - 0.034 14.4 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 AAAP01003053.1_2 - 0.066 13.0 0.1 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 MukB N-terminal Mg_chelatase PF01078.21 AAAP01003053.1_2 - 0.083 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 AAAP01003053.1_2 - 0.089 12.8 0.0 0.3 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003053.1_2 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003053.1_2 - 0.11 12.5 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AAAP01003053.1_2 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 AAAP01003053.1_2 - 0.2 12.2 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PTPS PF01242.19 AAAP01003055.1_1 - 9e-36 122.5 0.0 1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Radical_SAM PF04055.21 AAAP01003055.1_2 - 8.9e-08 32.7 0.0 1e-07 32.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAAP01003055.1_2 - 3.5e-05 23.9 0.0 8.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAAP01003055.1_2 - 0.013 15.8 0.2 0.028 14.7 0.2 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain Peptidase_S11 PF00768.20 AAAP01003055.1_3 - 4.4e-16 59.0 0.0 4.9e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAAP01003055.1_3 - 2.9e-08 33.6 0.0 3.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AAAP01003055.1_3 - 0.00013 20.8 0.1 0.00015 20.6 0.1 1.1 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AAAP01003055.1_3 - 0.00046 19.5 0.1 0.00046 19.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Transpeptidase PF00905.22 AAAP01003055.1_3 - 0.068 12.4 0.1 0.084 12.1 0.1 1.1 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Polysacc_deac_1 PF01522.21 AAAP01003056.1_1 - 1.4e-14 54.0 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase TonB_dep_Rec PF00593.24 AAAP01003057.1_1 - 4.5e-56 191.7 19.8 5.2e-56 191.5 19.8 1.0 1 0 0 1 1 1 1 TonB dependent receptor BBP2_2 PF10082.9 AAAP01003059.1_1 - 6.8e-106 354.3 6.1 7.6e-106 354.1 6.1 1.0 1 0 0 1 1 1 1 Putative beta-barrel porin 2 OMP_b-brl PF13505.6 AAAP01003059.1_1 - 3.7e-05 23.9 1.0 0.0028 17.8 1.0 2.3 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain Inh PF02974.14 AAAP01003059.1_2 - 4.3e-17 62.0 0.0 5.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protease inhibitor Inh NMT1_2 PF13379.6 AAAP01003060.1_1 - 6.9e-10 39.0 0.1 9.2e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01003060.1_1 - 1.5e-09 38.1 0.0 2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAAP01003060.1_1 - 1.6e-08 34.5 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAAP01003060.1_1 - 1.9e-07 30.8 0.0 5.6e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AAAP01003060.1_1 - 1.6e-06 27.9 0.0 3.1e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AAAP01003060.1_1 - 0.002 17.6 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family TraW_N PF12477.8 AAAP01003060.1_1 - 0.55 10.2 4.9 0.79 9.8 0.1 2.7 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Bac_luciferase PF00296.20 AAAP01003060.1_2 - 1.6e-88 297.1 3.0 1.9e-88 296.9 3.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DEDD_Tnp_IS110 PF01548.17 AAAP01003061.1_1 - 7.2e-22 77.9 0.0 1.2e-21 77.2 0.0 1.3 1 1 0 1 1 1 1 Transposase DUF4726 PF15855.5 AAAP01003061.1_1 - 0.011 15.9 3.3 2 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) FoP_duplication PF13865.6 AAAP01003062.1_3 - 0.038 14.5 1.5 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Oleosin PF01277.17 AAAP01003062.1_3 - 0.21 11.4 0.1 0.27 11.0 0.1 1.1 1 0 0 1 1 1 0 Oleosin Cation_efflux PF01545.21 AAAP01003062.1_4 - 1.9e-40 138.7 8.8 2.4e-40 138.4 8.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003062.1_4 - 1.8e-22 79.2 2.3 2.8e-22 78.6 2.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PepSY_TM PF03929.16 AAAP01003062.1_5 - 9.5 5.8 11.7 0.8 9.3 5.1 2.1 2 0 0 2 2 2 0 PepSY-associated TM region CorA PF01544.18 AAAP01003063.1_1 - 5.1e-39 134.3 0.2 6.4e-39 134.0 0.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DisA-linker PF10635.9 AAAP01003063.1_1 - 0.026 14.3 0.6 0.071 12.9 0.1 1.7 1 1 1 2 2 2 0 DisA bacterial checkpoint controller linker region HWE_HK PF07536.14 AAAP01003063.1_1 - 0.1 13.3 1.0 0.38 11.5 0.2 2.0 1 1 1 2 2 2 0 HWE histidine kinase DUF4198 PF10670.9 AAAP01003063.1_2 - 4e-31 109.0 1.0 4.9e-31 108.8 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) CarboxypepD_reg PF13620.6 AAAP01003063.1_2 - 0.0003 21.0 0.5 0.00064 20.0 0.5 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 AAAP01003063.1_2 - 0.048 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) AMP-binding PF00501.28 AAAP01003064.1_1 - 6.1e-68 229.3 0.0 7.1e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 AAAP01003064.1_1 - 1.7e-21 75.8 0.8 4.6e-21 74.5 0.8 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus HATPase_c PF02518.26 AAAP01003064.1_2 - 8.7e-12 45.5 0.0 1e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003064.1_2 - 0.016 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003064.1_2 - 0.065 13.1 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FtsK_SpoIIIE PF01580.18 AAAP01003065.1_2 - 2e-31 109.2 0.0 2.7e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_alpha PF17854.1 AAAP01003065.1_2 - 1.4e-27 95.7 0.0 2.2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 FtsK alpha domain T2SSE PF00437.20 AAAP01003065.1_2 - 0.00079 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF87 PF01935.17 AAAP01003065.1_2 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 AAAP01003065.1_2 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 AAAP01003065.1_2 - 0.012 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 AAAP01003065.1_2 - 0.04 13.7 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 AAAP01003065.1_2 - 0.22 11.3 0.1 0.46 10.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 AAAP01003065.1_2 - 0.22 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region EcsC PF12787.7 AAAP01003066.1_1 - 1.4e-34 119.9 0.2 1.6e-34 119.7 0.2 1.0 1 0 0 1 1 1 1 EcsC protein family NnrU PF07298.11 AAAP01003066.1_3 - 0.016 14.7 0.9 0.016 14.7 0.9 1.0 1 0 0 1 1 1 0 NnrU protein Deltameth_res PF16020.5 AAAP01003066.1_3 - 0.25 11.3 0.7 0.25 11.3 0.7 1.0 1 0 0 1 1 1 0 Deltamethrin resistance FSAP_sig_propep PF03032.15 AAAP01003066.1_3 - 3.5 7.7 4.4 15 5.7 4.4 1.8 1 1 0 1 1 1 0 Frog skin active peptide family signal and propeptide AAA_19 PF13245.6 AAAP01003067.1_1 - 1e-09 38.9 0.1 0.00082 19.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAAP01003067.1_1 - 3.3e-07 30.3 0.0 0.018 14.8 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 AAAP01003067.1_1 - 2.2e-06 27.3 0.0 0.0012 18.3 0.0 2.4 3 0 0 3 3 3 2 PhoH-like protein UvrD-helicase PF00580.21 AAAP01003067.1_1 - 5.8e-06 26.0 0.0 0.035 13.6 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 AAAP01003067.1_1 - 1e-05 25.3 0.1 3.1e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAAP01003067.1_1 - 0.00032 20.5 4.8 0.16 11.7 0.5 2.7 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 AAAP01003067.1_1 - 0.00072 18.9 0.4 0.013 14.8 0.2 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 AAAP01003067.1_1 - 0.0021 17.5 0.0 0.0052 16.2 0.0 1.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF2388 PF09498.10 AAAP01003067.1_1 - 0.016 15.2 0.7 0.044 13.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) AAA_11 PF13086.6 AAAP01003067.1_1 - 0.016 15.0 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAAP01003067.1_1 - 0.053 13.8 0.5 2.4 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain SIP PF04954.13 AAAP01003067.1_2 - 6.8e-09 36.3 0.0 7.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Siderophore-interacting protein Phospholip_A2_1 PF00068.19 AAAP01003068.1_1 - 2.9e-05 24.5 0.0 4.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 OMP_b-brl PF13505.6 AAAP01003068.1_2 - 7.1e-08 32.8 7.4 9e-08 32.4 7.4 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain UbiA PF01040.18 AAAP01003069.1_1 - 9.6e-27 93.9 31.8 1.3e-26 93.5 31.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Chal_sti_synt_N PF00195.19 AAAP01003069.1_2 - 8.3e-20 71.2 0.7 3e-19 69.3 0.3 2.0 2 1 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 AAAP01003069.1_2 - 1.3e-14 54.4 0.0 5.6e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 AAAP01003069.1_2 - 2.4e-13 50.1 0.0 1.5e-11 44.3 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 AAAP01003069.1_2 - 4.1e-10 39.4 0.0 3.6e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 AAAP01003069.1_2 - 3.9e-07 29.8 0.3 8.6e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AAAP01003069.1_2 - 0.00049 19.5 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAAP01003069.1_2 - 0.088 12.8 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain RuvB_N PF05496.12 AAAP01003069.1_2 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 AAAP01003070.1_1 - 1.9e-05 24.5 0.1 2.1e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sulfotransfer_1 PF00685.27 AAAP01003070.1_2 - 6.7e-06 25.8 0.0 9.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 AAAP01003070.1_2 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family HD_5 PF13487.6 AAAP01003070.1_3 - 2.4e-10 40.5 0.2 4.4e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003070.1_3 - 0.0046 17.2 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 HD domain Ribosomal_L17 PF01196.19 AAAP01003071.1_2 - 3.3e-33 114.5 0.0 3.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_A_CTD PF03118.15 AAAP01003071.1_3 - 5.4e-25 86.9 0.1 1.1e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 AAAP01003071.1_3 - 7.4e-24 84.3 0.0 3.5e-23 82.1 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AAAP01003071.1_3 - 1.9e-23 81.7 0.0 3.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF211 PF02680.14 AAAP01003071.1_3 - 0.0098 16.0 0.2 3.1 8.0 0.1 2.4 2 0 0 2 2 2 2 Uncharacterized ArCR, COG1888 RNA_pol_L_2 PF13656.6 AAAP01003071.1_3 - 0.043 13.6 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.28 AAAP01003072.1_2 - 7.9e-11 42.1 0.1 1.1e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain TusA PF01206.17 AAAP01003072.1_3 - 3.1e-18 65.4 0.0 3.6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AAAP01003072.1_3 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) TraT PF05818.12 AAAP01003072.1_4 - 2.1 8.0 4.8 2.5 7.7 4.8 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GIY-YIG PF01541.24 AAAP01003073.1_1 - 8.6e-11 42.0 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain CheZ PF04344.13 AAAP01003073.1_2 - 3.5e-10 40.2 3.6 2.7e-08 34.0 3.7 2.4 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ UCR_14kD PF02271.16 AAAP01003073.1_2 - 0.047 13.7 0.9 0.2 11.6 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit CorA PF01544.18 AAAP01003073.1_2 - 0.28 10.5 2.1 0.52 9.6 1.4 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CCDC-167 PF15188.6 AAAP01003073.1_2 - 0.32 11.4 1.8 14 6.1 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 CitT PF12431.8 AAAP01003073.1_2 - 0.7 10.3 5.0 1.4 9.4 1.4 2.5 2 0 0 2 2 2 0 Transcriptional regulator YkuD PF03734.14 AAAP01003073.1_3 - 2.6e-16 60.4 0.0 3.9e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Syntaxin-6_N PF09177.11 AAAP01003074.1_1 - 0.19 12.3 2.7 0.94 10.1 1.3 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 AAAP01003074.1_1 - 0.83 10.2 9.4 17 5.9 1.6 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GvpL_GvpF PF06386.11 AAAP01003074.1_1 - 8.7 6.2 13.1 0.58 10.0 7.8 1.7 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF4096 PF13340.6 AAAP01003075.1_1 - 2.1e-19 69.5 4.6 2.7e-19 69.2 4.6 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) LRR_RI_capping PF18779.1 AAAP01003075.1_1 - 0.0075 15.9 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 Capping Ribonuclease inhibitor Leucine Rich Repeat Na_H_Exchanger PF00999.21 AAAP01003076.1_1 - 3.7e-56 190.6 43.0 4.6e-56 190.3 43.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AAAP01003076.1_1 - 6.8e-12 45.7 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAAP01003076.1_1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AAAP01003076.1_1 - 0.055 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NACHT PF05729.12 AAAP01003077.1_1 - 1.8e-24 86.5 0.0 7.8e-24 84.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AAAP01003077.1_1 - 0.00039 20.1 0.1 0.0026 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAAP01003077.1_1 - 0.0021 18.3 0.0 0.0078 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01003077.1_1 - 0.0038 17.0 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAAP01003077.1_1 - 0.0047 16.0 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 AAAP01003077.1_1 - 0.015 15.1 0.3 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003077.1_1 - 0.025 15.1 0.3 0.076 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAAP01003077.1_1 - 0.027 14.8 0.4 0.027 14.8 0.4 3.4 2 2 1 3 3 3 0 AAA ATPase domain dNK PF01712.19 AAAP01003077.1_1 - 0.038 13.8 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase cobW PF02492.19 AAAP01003077.1_1 - 0.061 12.9 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AAAP01003077.1_1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAAP01003077.1_1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HEPN_Toprim_N PF18871.1 AAAP01003077.1_1 - 0.089 12.7 0.2 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 FtsK_SpoIIIE PF01580.18 AAAP01003077.1_1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 AAAP01003077.1_1 - 0.16 12.5 0.0 0.48 10.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Herpes_Helicase PF02689.14 AAAP01003077.1_1 - 0.24 9.2 0.0 0.35 8.7 0.0 1.1 1 0 0 1 1 1 0 Helicase MFS_1 PF07690.16 AAAP01003078.1_1 - 1.8e-14 53.5 67.0 1.9e-10 40.2 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AAAP01003078.1_1 - 8.5e-12 44.2 44.6 1.3e-11 43.6 44.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Pyr_redox_2 PF07992.14 AAAP01003078.1_2 - 5.7e-18 65.2 0.1 3.6e-13 49.4 0.0 2.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003078.1_2 - 1.8e-17 63.6 0.0 8.4e-17 61.4 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AAAP01003078.1_2 - 2.4e-09 36.2 0.0 1.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 AAAP01003078.1_2 - 3.8e-08 32.9 0.1 2.6e-05 23.6 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AAAP01003078.1_2 - 5.3e-08 32.8 8.4 7.1e-06 25.8 0.2 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003078.1_2 - 7.2e-08 32.5 2.8 8.2e-08 32.4 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAAP01003078.1_2 - 7.8e-07 28.6 0.3 2.8e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 AAAP01003078.1_2 - 3.3e-06 26.4 1.4 8e-06 25.2 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AAAP01003078.1_2 - 0.00033 21.1 0.3 1.1 9.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01003078.1_2 - 0.00099 18.4 0.5 0.0017 17.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAAP01003078.1_2 - 0.0014 17.4 1.0 0.0036 16.1 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 AAAP01003078.1_2 - 0.0023 17.1 0.2 0.0023 17.1 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 AAAP01003078.1_2 - 0.0029 18.0 0.1 2.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 AAAP01003078.1_2 - 0.0034 16.5 0.2 0.0034 16.5 0.2 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 AAAP01003078.1_2 - 0.0034 16.8 0.6 0.0034 16.8 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAAP01003078.1_2 - 0.0085 15.4 0.1 0.0085 15.4 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AAAP01003078.1_2 - 0.061 13.3 1.7 5.4 7.0 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Peptidase_M17_N PF02789.17 AAAP01003078.1_2 - 0.081 12.8 3.1 12 5.7 0.1 3.2 3 0 0 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain Shikimate_DH PF01488.20 AAAP01003078.1_2 - 0.21 11.7 0.0 7 6.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01003078.1_2 - 2.9 7.2 4.7 0.91 8.8 0.9 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Hepar_II_III PF07940.13 AAAP01003079.1_1 - 4.7e-40 137.7 0.1 6.8e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein SCO1-SenC PF02630.14 AAAP01003080.1_1 - 1.4e-15 57.4 0.0 1.6e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAAP01003080.1_1 - 0.24 11.3 0.0 0.31 11.0 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Lactamase_B PF00753.27 AAAP01003080.1_2 - 1.2e-10 41.8 0.8 2.4e-10 40.7 0.3 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily TAT_signal PF10518.9 AAAP01003080.1_2 - 1.6e-05 24.6 0.6 3.4e-05 23.5 0.6 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Lactamase_B_2 PF12706.7 AAAP01003080.1_2 - 9.5e-05 22.0 0.1 0.0002 21.0 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AAAP01003080.1_2 - 0.00097 19.1 0.2 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AAAP01003080.1_2 - 0.051 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Cpn10 PF00166.21 AAAP01003080.1_3 - 2.4e-28 98.0 0.0 2.6e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit SLT PF01464.20 AAAP01003081.1_1 - 9.5e-17 60.7 0.0 1.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Sox_N PF12444.8 AAAP01003081.1_1 - 0.07 14.3 0.1 0.15 13.2 0.1 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal ACR_tran PF00873.19 AAAP01003082.1_1 - 2.6e-55 187.6 12.3 3.1e-55 187.4 12.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003082.1_1 - 0.02 13.9 14.3 0.027 13.4 14.3 1.2 1 0 0 1 1 1 0 MMPL family SecD_SecF PF02355.16 AAAP01003082.1_1 - 0.023 14.1 5.1 0.03 13.7 5.1 1.1 1 0 0 1 1 1 0 Protein export membrane protein Cytochrom_C PF00034.21 AAAP01003082.1_2 - 2.5e-05 25.3 0.0 5.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003082.1_2 - 0.00019 21.7 0.2 0.00043 20.5 0.2 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Bac_DnaA_C PF08299.11 AAAP01003083.1_1 - 5.3e-15 55.2 0.1 8.8e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix HNH PF01844.23 AAAP01003083.1_2 - 1.2e-09 38.2 1.0 1.5e-09 37.8 1.0 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 AAAP01003083.1_2 - 7.1e-08 32.2 0.2 1.1e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease Cytochrome_C7 PF14522.6 AAAP01003083.1_2 - 0.0093 15.9 0.3 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c HNH_3 PF13392.6 AAAP01003083.1_3 - 1.6e-11 43.8 0.7 2.5e-11 43.2 0.7 1.3 1 0 0 1 1 1 1 HNH endonuclease zf-His_Me_endon PF05551.11 AAAP01003083.1_3 - 0.0045 17.2 2.1 0.0076 16.4 2.1 1.5 1 1 0 1 1 1 1 Zinc-binding loop region of homing endonuclease HTH_23 PF13384.6 AAAP01003083.1_3 - 0.043 13.6 0.2 0.096 12.5 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAAP01003083.1_3 - 0.093 12.2 1.9 0.22 11.0 0.6 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 adh_short PF00106.25 AAAP01003084.1_1 - 2.2e-21 76.2 2.0 2.6e-21 76.0 2.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003084.1_1 - 2e-16 60.3 4.2 2.3e-16 60.0 4.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003084.1_1 - 1.6e-09 38.0 0.6 1.9e-09 37.7 0.6 1.0 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 AAAP01003084.1_1 - 0.01 15.2 0.1 0.015 14.7 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2460 PF09343.10 AAAP01003084.1_1 - 0.033 13.7 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) Epimerase PF01370.21 AAAP01003084.1_1 - 0.035 13.6 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TLP1_add_C PF18313.1 AAAP01003084.1_1 - 0.16 12.0 3.2 0.32 10.9 3.2 1.6 1 1 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain 3HCDH_N PF02737.18 AAAP01003084.1_1 - 0.2 11.5 1.4 0.24 11.3 1.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 AAAP01003084.1_1 - 0.31 10.6 2.1 0.34 10.4 2.1 1.1 1 0 0 1 1 1 0 NmrA-like family DUF2809 PF10990.8 AAAP01003084.1_2 - 3.7e-21 75.6 3.9 4.2e-21 75.4 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2809) RF-1 PF00472.20 AAAP01003084.1_4 - 1.7e-35 121.4 0.1 2.2e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 AAAP01003084.1_4 - 1e-06 28.8 0.8 2.1e-06 27.7 0.3 1.7 2 0 0 2 2 2 1 PCRF domain PHB_depo_C PF06850.11 AAAP01003085.1_1 - 2.5e-28 98.9 0.0 3.5e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 PHB de-polymerase C-terminus GST_N_3 PF13417.6 AAAP01003085.1_2 - 4.1e-08 33.5 0.0 6.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003085.1_2 - 1e-07 31.9 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAAP01003085.1_2 - 3.6e-07 30.4 0.0 5.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AAAP01003085.1_2 - 0.0031 17.7 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAAP01003085.1_2 - 0.047 14.0 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CBM_48 PF02922.18 AAAP01003086.1_1 - 4e-20 71.9 0.0 9.7e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 AAAP01003086.1_1 - 0.023 14.9 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase TetR_C_33 PF13305.6 AAAP01003087.1_1 - 2.7e-13 50.6 7.9 3.3e-13 50.3 7.9 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 AAAP01003087.1_1 - 0.0038 18.0 2.9 0.0053 17.5 2.9 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Leu_Phe_trans PF03588.14 AAAP01003087.1_2 - 2.7e-64 215.7 0.0 3.2e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 AAAP01003087.1_2 - 0.028 14.6 1.7 0.054 13.7 1.7 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF550 PF04447.12 AAAP01003088.1_1 - 7.9e-05 22.7 0.5 0.0004 20.4 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF550) DUF4936 PF16290.5 AAAP01003088.1_1 - 0.62 10.8 4.1 28 5.5 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4936) AAA PF00004.29 AAAP01003089.1_1 - 1.4e-14 54.7 0.0 2.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAAP01003089.1_1 - 4.3e-14 52.6 0.0 7.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAAP01003089.1_1 - 1.6e-07 31.4 0.1 1.9e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003089.1_1 - 2.1e-07 31.5 0.7 0.00071 20.0 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AAAP01003089.1_1 - 1.4e-06 28.6 0.1 0.00075 19.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AAAP01003089.1_1 - 1.5e-06 27.7 0.1 0.03 13.7 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AAAP01003089.1_1 - 1.1e-05 25.2 0.0 0.0071 16.1 0.0 2.1 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 AAAP01003089.1_1 - 2.4e-05 24.2 0.0 5.2e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01003089.1_1 - 2.5e-05 24.1 0.1 0.12 12.1 0.1 2.1 1 1 1 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 AAAP01003089.1_1 - 0.00012 22.2 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 AAAP01003089.1_1 - 0.00032 20.5 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 AAAP01003089.1_1 - 0.00051 20.6 0.0 0.00083 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AAAP01003089.1_1 - 0.00059 19.9 0.0 0.42 10.6 0.0 2.1 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AAAP01003089.1_1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003089.1_1 - 0.0017 18.5 0.1 0.0036 17.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AAAP01003089.1_1 - 0.0018 18.4 0.0 0.0055 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 AAAP01003089.1_1 - 0.0041 17.4 0.1 0.0063 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AAAP01003089.1_1 - 0.005 17.2 0.0 0.0081 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 AAAP01003089.1_1 - 0.0072 16.7 0.2 0.89 9.9 0.2 2.1 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 AAAP01003089.1_1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003089.1_1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003089.1_1 - 0.028 14.0 0.2 0.054 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AAAP01003089.1_1 - 0.028 14.1 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Rad17 PF03215.15 AAAP01003089.1_1 - 0.031 14.2 0.0 0.062 13.2 0.0 1.4 1 1 1 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 AAAP01003089.1_1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 AAAP01003089.1_1 - 0.062 13.0 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 AAAP01003089.1_1 - 0.074 13.2 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate kinase RsgA_GTPase PF03193.16 AAAP01003089.1_1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Resolvase PF00239.21 AAAP01003089.1_1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Resolvase, N terminal domain ABC_tran PF00005.27 AAAP01003089.1_1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 AAAP01003089.1_1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 AAAP01003089.1_1 - 0.26 10.3 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 AAAP01003089.1_1 - 0.29 10.3 0.0 0.36 10.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain SBP_bac_11 PF13531.6 AAAP01003089.1_2 - 1e-07 32.0 0.0 1.1e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4781 PF16013.5 AAAP01003090.1_1 - 0.051 12.4 3.4 0.055 12.3 3.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4781) PAS_3 PF08447.12 AAAP01003090.1_2 - 2.6e-11 43.7 0.0 4.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003090.1_2 - 5.9e-10 39.2 0.0 8.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003090.1_2 - 2.4e-05 24.5 0.0 3.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003090.1_2 - 0.0076 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003090.1_2 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 PAS fold PAS_7 PF12860.7 AAAP01003091.1_1 - 7.2e-30 103.5 0.0 2.4e-18 66.4 0.0 4.2 3 2 0 3 3 3 2 PAS fold HAMP PF00672.25 AAAP01003091.1_1 - 4.9e-10 39.6 0.2 2.1e-09 37.6 0.2 2.2 1 0 0 1 1 1 1 HAMP domain PAS PF00989.25 AAAP01003091.1_1 - 8.1e-10 38.7 0.2 7e-06 26.0 0.1 3.2 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01003091.1_1 - 2e-09 37.3 0.4 0.0004 20.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain 4HB_MCP_1 PF12729.7 AAAP01003091.1_1 - 1.3e-08 34.6 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction PAS_4 PF08448.10 AAAP01003091.1_1 - 9.8e-07 29.0 0.2 0.052 13.8 0.0 3.2 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003091.1_1 - 0.00024 21.3 0.0 0.015 15.6 0.0 2.7 2 1 0 2 2 2 1 PAS domain TarH PF02203.15 AAAP01003091.1_1 - 0.0093 15.9 1.4 0.024 14.5 1.4 1.7 1 0 0 1 1 1 1 Tar ligand binding domain homologue PepSY_TM PF03929.16 AAAP01003091.1_1 - 0.028 14.1 1.6 0.047 13.3 1.0 1.5 1 1 0 1 1 1 0 PepSY-associated TM region Cupredoxin_1 PF13473.6 AAAP01003091.1_2 - 1.5e-05 25.0 0.0 1.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 AAAP01003091.1_2 - 0.049 14.1 0.0 0.51 10.8 0.0 2.0 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family CCP_MauG PF03150.14 AAAP01003091.1_3 - 2.9e-32 112.4 0.0 3.8e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase DsbD PF02683.15 AAAP01003092.1_1 - 3.9e-47 160.9 11.7 4.4e-47 160.7 11.7 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Borrelia_P13 PF05628.12 AAAP01003092.1_1 - 6.3 6.8 8.7 2.9 7.9 2.0 2.7 2 2 0 2 2 2 0 Borrelia membrane protein P13 MtrC PF04211.13 AAAP01003092.1_1 - 8.6 5.3 14.5 0.18 10.8 7.7 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C HTH_5 PF01022.20 AAAP01003092.1_2 - 1.5e-14 53.6 0.1 2.5e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01003092.1_2 - 5.6e-11 42.3 0.1 1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01003092.1_2 - 5.3e-07 29.4 0.1 8.9e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAAP01003092.1_2 - 1.9e-06 27.6 0.1 3.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AAAP01003092.1_2 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB RP-C PF03428.13 AAAP01003092.1_2 - 0.001 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Replication protein C N-terminal domain DprA_WH PF17782.1 AAAP01003092.1_2 - 0.0017 18.5 0.1 0.0028 17.7 0.1 1.3 1 0 0 1 1 1 1 DprA winged helix domain MarR PF01047.22 AAAP01003092.1_2 - 0.0039 17.1 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01003092.1_2 - 0.0075 16.7 0.0 0.021 15.3 0.0 1.7 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_9 PF08221.11 AAAP01003092.1_2 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HNF-1_N PF04814.13 AAAP01003092.1_2 - 0.011 16.3 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Cdc6_C PF09079.11 AAAP01003092.1_2 - 0.019 14.9 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DUF4423 PF14394.6 AAAP01003092.1_2 - 0.04 13.6 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_45 PF14947.6 AAAP01003092.1_2 - 0.047 13.7 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_24 PF13412.6 AAAP01003092.1_2 - 0.051 13.1 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding PaaX PF07848.12 AAAP01003092.1_2 - 0.053 13.8 0.1 0.19 12.0 0.0 1.8 1 1 1 2 2 2 0 PaaX-like protein Rio2_N PF09202.11 AAAP01003092.1_2 - 0.069 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Rio2, N-terminal UDPG_MGDP_dh PF00984.19 AAAP01003093.1_1 - 4.7e-28 97.2 0.0 8.7e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAAP01003093.1_1 - 2.5e-27 95.3 0.2 6.4e-27 94.0 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01003093.1_1 - 2.4e-08 33.8 0.0 1.7e-07 31.0 0.0 2.2 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AAAP01003093.1_1 - 2.2e-05 24.9 1.3 0.00026 21.5 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 AAAP01003093.1_1 - 0.059 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DotU PF09850.9 AAAP01003093.1_2 - 0.19 11.4 0.3 0.19 11.4 0.3 1.0 1 0 0 1 1 1 0 Type VI secretion system protein DotU Glyco_transf_9 PF01075.17 AAAP01003093.1_4 - 1.9e-25 89.6 0.0 3.7e-25 88.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) OEP PF02321.18 AAAP01003094.1_1 - 5.6e-13 49.1 18.5 2.8e-09 37.1 3.4 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein TTKRSYEDQ PF10212.9 AAAP01003094.1_1 - 0.16 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF402 PF04167.13 AAAP01003095.1_1 - 0.17 12.1 0.0 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF402) DUF4872 PF16169.5 AAAP01003095.1_2 - 0.092 12.5 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) BCA_ABC_TP_C PF12399.8 AAAP01003096.1_2 - 0.065 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter ABC_tran PF00005.27 AAAP01003096.1_3 - 6e-20 72.2 0.0 7.1e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003096.1_3 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003096.1_3 - 0.029 14.1 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAAP01003096.1_3 - 0.042 13.9 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01003096.1_3 - 0.2 11.0 0.1 2.1 7.7 0.1 1.9 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003096.1_3 - 0.25 11.8 0.0 0.34 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Glycos_transf_3 PF00591.21 AAAP01003097.1_3 - 1.8e-40 139.2 3.0 2.5e-40 138.7 3.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 AAAP01003097.1_3 - 1.9e-21 75.5 0.5 3.9e-21 74.5 0.5 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2254 PF10011.9 AAAP01003097.1_3 - 0.016 14.1 0.0 0.058 12.2 0.0 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) Peptidase_M23 PF01551.22 AAAP01003097.1_3 - 0.19 11.9 0.3 0.85 9.9 0.0 2.2 2 1 0 2 2 2 0 Peptidase family M23 SGL PF08450.12 AAAP01003098.1_1 - 2.3e-17 63.4 1.2 0.016 14.8 0.0 6.4 1 1 6 7 7 7 5 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 AAAP01003098.1_1 - 6.8e-09 34.9 0.1 3.5 8.2 0.0 6.4 6 0 0 6 6 6 2 Two component regulator propeller Phytase-like PF13449.6 AAAP01003098.1_1 - 3.4e-08 33.8 1.0 0.054 13.4 0.0 5.2 1 1 4 5 5 5 2 Esterase-like activity of phytase NHL PF01436.21 AAAP01003098.1_1 - 8.8e-05 22.4 1.8 3.5 7.8 0.1 5.0 6 0 0 6 6 6 2 NHL repeat DUF2255 PF10012.9 AAAP01003098.1_1 - 0.0082 16.3 0.0 8.5 6.6 0.0 4.1 5 1 1 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2255) Ldl_recept_b PF00058.17 AAAP01003098.1_1 - 0.074 13.5 0.0 8 7.0 0.0 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Aft1_HRA PF11786.8 AAAP01003098.1_1 - 0.13 12.6 5.9 4.8 7.6 0.8 3.3 2 1 0 3 3 3 0 Aft1 HRA domain Sox17_18_mid PF12067.8 AAAP01003098.1_1 - 3.5 7.7 6.3 6.4 6.9 0.0 2.9 3 0 0 3 3 3 0 Sox 17/18 central domain MerT PF02411.15 AAAP01003098.1_2 - 6.1e-31 106.9 4.9 1.1e-30 106.0 4.9 1.4 1 0 0 1 1 1 1 MerT mercuric transport protein PRA-CH PF01502.18 AAAP01003098.1_2 - 1.8e-30 104.6 0.5 2.6e-30 104.1 0.5 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase OppC_N PF12911.7 AAAP01003098.1_2 - 0.049 13.6 2.0 0.049 13.6 2.0 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HMA PF00403.26 AAAP01003098.1_3 - 4.7e-07 30.2 0.1 6.9e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain ACR_tran PF00873.19 AAAP01003098.1_3 - 0.21 9.2 0.0 0.23 9.1 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MFS_1 PF07690.16 AAAP01003099.1_1 - 5.7e-18 65.0 10.5 5.7e-18 65.0 10.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAAP01003099.1_1 - 0.00049 18.8 4.4 0.0009 17.9 4.4 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 AAAP01003099.1_1 - 0.0029 16.6 3.8 0.0043 16.0 3.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3313 PF11769.8 AAAP01003099.1_2 - 1.2e-40 139.4 0.2 1.5e-40 139.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) FBPase_glpX PF03320.13 AAAP01003100.1_1 - 3e-130 433.6 5.7 3.4e-130 433.4 5.7 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Homoserine_dh PF00742.19 AAAP01003100.1_2 - 4.5e-33 114.6 2.2 7e-33 114.0 1.6 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase ACT PF01842.25 AAAP01003100.1_2 - 6.2e-10 38.7 0.3 2.7e-09 36.6 0.1 2.3 2 1 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AAAP01003100.1_2 - 0.024 15.2 0.2 0.28 11.8 0.0 2.4 2 0 0 2 2 2 0 ACT domain LysR_substrate PF03466.20 AAAP01003101.1_1 - 1.8e-40 138.6 0.4 2e-40 138.4 0.4 1.0 1 0 0 1 1 1 1 LysR substrate binding domain DHquinase_II PF01220.19 AAAP01003101.1_2 - 4.1e-54 182.0 0.2 4.7e-54 181.8 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Biotin_lipoyl PF00364.22 AAAP01003101.1_3 - 9.4e-18 63.8 0.0 2.7e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAAP01003101.1_3 - 3.6e-05 23.5 0.1 0.002 17.9 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 AAAP01003101.1_3 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 AAAP01003101.1_3 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AAAP01003101.1_3 - 0.13 11.5 0.0 0.39 9.9 0.0 1.8 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion YqfD PF06898.11 AAAP01003101.1_3 - 0.22 10.3 0.1 0.49 9.2 0.0 1.7 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD Biotin_carb_N PF00289.22 AAAP01003101.1_4 - 8.4e-19 68.1 0.0 1e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain LpxI_N PF17930.1 AAAP01003101.1_4 - 0.049 13.5 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 LpxI N-terminal domain Exo_endo_phos PF03372.23 AAAP01003102.1_1 - 2.6e-10 40.2 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ceramidase PF05875.12 AAAP01003102.1_2 - 8.6e-10 38.5 4.6 6.3e-09 35.6 4.6 1.9 1 1 0 1 1 1 1 Ceramidase Per1 PF04080.13 AAAP01003102.1_2 - 0.31 10.8 1.9 0.49 10.1 1.9 1.3 1 1 0 1 1 1 0 Per1-like family DUF599 PF04654.12 AAAP01003103.1_1 - 8.8e-56 188.6 9.8 1e-55 188.4 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 PhoR PF11808.8 AAAP01003103.1_1 - 7.2 7.1 12.1 0.75 10.2 2.8 3.0 3 1 0 3 3 3 0 Phosphate regulon sensor protein PhoR DUF3253 PF11625.8 AAAP01003103.1_2 - 1.3e-29 102.2 0.0 1.5e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) NUDIX PF00293.28 AAAP01003104.1_1 - 2.1e-15 56.9 0.1 4.3e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 AAAP01003104.1_1 - 1.6e-08 34.0 9.1 3e-08 33.2 9.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 AAAP01003104.1_1 - 7.6e-08 32.9 3.5 2e-07 31.6 2.8 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain Trp_syntA PF00290.20 AAAP01003104.1_2 - 1e-28 99.9 0.0 1.1e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain BacA PF02673.18 AAAP01003105.1_1 - 1.1e-22 81.1 0.2 1.1e-22 81.0 0.2 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA Hemerythrin PF01814.23 AAAP01003105.1_2 - 2.3e-13 50.9 3.8 2.8e-13 50.6 3.8 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TetR_C_31 PF17940.1 AAAP01003105.1_2 - 0.056 13.6 0.9 0.076 13.2 0.9 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ADH_zinc_N_2 PF13602.6 AAAP01003105.1_3 - 1.6e-23 84.2 0.1 1.8e-23 84.1 0.1 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AAAP01003105.1_3 - 4.5e-08 33.1 0.1 6.5e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1726 PF08351.11 AAAP01003105.1_3 - 0.11 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DMT_YdcZ PF04657.13 AAAP01003106.1_1 - 2.7e-30 105.5 20.3 3.2e-30 105.2 20.3 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ FA_desaturase PF00487.24 AAAP01003106.1_1 - 0.16 11.8 5.6 0.18 11.6 5.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Neurensin PF14927.6 AAAP01003106.1_1 - 8.2 6.1 7.9 0.84 9.3 0.2 2.5 2 1 0 2 2 2 0 Neurensin ECH_1 PF00378.20 AAAP01003106.1_2 - 1.6e-41 142.3 0.0 1.7e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003106.1_2 - 1.1e-23 84.2 0.0 1.4e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase BMC PF00936.19 AAAP01003106.1_2 - 0.27 11.2 1.9 0.58 10.2 0.1 2.3 3 0 0 3 3 3 0 BMC domain adh_short PF00106.25 AAAP01003106.1_3 - 2.1e-19 69.8 0.0 1e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003106.1_3 - 1.9e-18 66.9 0.0 6.3e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003106.1_3 - 0.012 15.5 1.4 0.027 14.4 0.3 1.9 2 0 0 2 2 2 0 KR domain THF_DHG_CYH_C PF02882.19 AAAP01003106.1_3 - 0.025 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 AAAP01003106.1_3 - 0.089 12.2 0.1 0.21 11.0 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 AAAP01003106.1_4 - 2.2e-23 82.7 0.0 2.9e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003106.1_4 - 9.2e-21 74.5 0.0 1.3e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003106.1_4 - 0.00024 21.1 0.1 0.0003 20.8 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF3729 PF12526.8 AAAP01003107.1_1 - 1 10.9 6.6 1.1 10.9 4.5 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) SARG PF15385.6 AAAP01003107.1_1 - 2.9 7.0 5.6 3.7 6.7 5.6 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Methyltrans_RNA PF04452.14 AAAP01003107.1_2 - 1.8e-51 174.7 0.0 2e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Asparaginase PF00710.20 AAAP01003107.1_3 - 2.2e-26 92.6 0.1 2.9e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Ribosomal_S21 PF01165.20 AAAP01003108.1_2 - 1.6e-18 66.2 10.5 1.6e-18 66.2 10.5 1.6 1 1 1 2 2 2 1 Ribosomal protein S21 Flu_NP PF00506.18 AAAP01003108.1_2 - 0.14 10.8 1.7 0.16 10.6 1.7 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein DUF1967 PF09269.11 AAAP01003108.1_2 - 0.16 12.0 0.7 0.38 10.7 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) RF-1 PF00472.20 AAAP01003108.1_2 - 0.23 11.4 5.0 0.32 11.0 5.0 1.1 1 0 0 1 1 1 0 RF-1 domain Response_reg PF00072.24 AAAP01003108.1_3 - 3.9e-09 36.7 0.0 4.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GATase_4 PF13230.6 AAAP01003108.1_4 - 3.6e-17 62.1 0.1 5.1e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 AAAP01003108.1_4 - 1.4e-12 48.0 0.1 2.1e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Plug PF07715.15 AAAP01003109.1_2 - 0.014 15.9 0.1 0.11 13.1 0.0 2.3 3 0 0 3 3 3 0 TonB-dependent Receptor Plug Domain NinB PF05772.12 AAAP01003110.1_2 - 5.2e-39 133.1 0.1 6e-39 132.9 0.1 1.0 1 0 0 1 1 1 1 NinB protein DUF4043 PF13252.6 AAAP01003110.1_3 - 0.00035 19.8 0.0 0.00047 19.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4043) DsbD PF02683.15 AAAP01003110.1_4 - 2.3e-16 60.3 24.0 1.6e-15 57.6 24.0 2.1 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AAAP01003110.1_4 - 9.1e-11 42.1 24.6 1.3e-10 41.6 24.2 1.4 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Phage_integrase PF00589.22 AAAP01003111.1_1 - 2.2e-28 99.2 0.4 1.3e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 Phage integrase family Phage_int_SAM_3 PF14659.6 AAAP01003111.1_1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PGM_PMM_II PF02879.16 AAAP01003112.1_2 - 1.8e-26 92.8 1.3 2.1e-26 92.5 0.1 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 AAAP01003112.1_2 - 2.5e-22 79.1 0.0 5.1e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AAAP01003112.1_2 - 2.3e-16 60.0 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III HemolysinCabind PF00353.19 AAAP01003113.1_1 - 1e-27 95.7 205.0 6.7e-05 22.8 3.8 15.6 13 4 0 13 13 13 13 RTX calcium-binding nonapeptide repeat (4 copies) RHS_repeat PF05593.14 AAAP01003113.1_1 - 0.18 12.4 6.3 7.8 7.1 0.3 3.4 3 0 0 3 3 3 0 RHS Repeat Transposase_20 PF02371.16 AAAP01003114.1_2 - 6.7e-23 80.8 2.8 9.4e-23 80.3 0.2 1.9 1 1 1 2 2 2 2 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAAP01003114.1_3 - 4.6e-06 26.6 0.0 8.5e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Transposase ALGX PF16822.5 AAAP01003115.1_1 - 3.7e-08 33.4 0.1 4.2e-08 33.2 0.1 1.3 1 1 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX DHHW PF14286.6 AAAP01003115.1_1 - 0.079 12.3 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 DHHW protein Methyltransf_23 PF13489.6 AAAP01003115.1_2 - 3.3e-10 40.1 0.0 5.9e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003115.1_2 - 6.6e-05 23.6 0.0 0.00015 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003115.1_2 - 0.0083 16.7 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain YadA_anchor PF03895.15 AAAP01003115.1_3 - 0.073 13.2 0.1 17 5.6 0.0 2.3 2 0 0 2 2 2 0 YadA-like membrane anchor domain AMP-binding PF00501.28 AAAP01003116.1_2 - 5.8e-77 259.1 0.0 7.5e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003116.1_2 - 2.8e-09 37.8 1.0 1.1e-08 35.9 0.7 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Creatininase PF02633.14 AAAP01003116.1_3 - 1.8e-09 37.4 0.1 1.9e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase DUF346 PF03984.13 AAAP01003116.1_3 - 0.008 15.9 0.6 0.01 15.5 0.6 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) TetR_C_11 PF16859.5 AAAP01003117.1_1 - 0.13 12.6 6.3 1.6 9.1 1.5 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MotB_plug PF13677.6 AAAP01003117.1_2 - 1.1e-17 63.4 0.1 2e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAAP01003117.1_2 - 4.1e-05 23.9 0.0 0.00014 22.1 0.0 1.9 2 0 0 2 2 2 1 OmpA family TP_methylase PF00590.20 AAAP01003118.1_2 - 2.3e-07 30.9 0.1 3.1e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HEM4 PF02602.15 AAAP01003118.1_3 - 7.5e-40 136.7 2.3 7.5e-40 136.7 2.3 1.7 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD Trans_reg_C PF00486.28 AAAP01003118.1_3 - 1.4e-10 41.1 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal CbiX PF01903.17 AAAP01003118.1_4 - 2.6e-10 40.6 0.0 8.3e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 CbiX DUF5133 PF17196.4 AAAP01003118.1_4 - 0.15 12.3 2.6 6.8 7.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) MFS_1 PF07690.16 AAAP01003118.1_5 - 0.00033 19.7 26.0 0.00078 18.5 26.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AIRS PF00586.24 AAAP01003119.1_1 - 1e-06 29.3 0.1 1.1e-06 29.2 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AI-2E_transport PF01594.16 AAAP01003119.1_2 - 9.3e-58 195.9 32.7 1.1e-57 195.7 32.7 1.0 1 0 0 1 1 1 1 AI-2E family transporter HTH_Tnp_1 PF01527.20 AAAP01003120.1_2 - 0.1 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Transposase Aminotran_1_2 PF00155.21 AAAP01003121.1_1 - 2.5e-46 158.5 0.0 3e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01003121.1_1 - 4.9e-06 25.3 0.0 7.8e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAAP01003121.1_1 - 1.6e-05 24.3 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAAP01003121.1_1 - 0.045 13.1 0.4 0.14 11.4 0.4 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 AAAP01003121.1_1 - 0.12 11.0 0.1 1.3 7.7 0.1 2.0 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Nif11 PF07862.11 AAAP01003121.1_1 - 0.14 12.5 0.4 4.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Nif11 domain HisKA_3 PF07730.13 AAAP01003121.1_1 - 4.3 7.9 6.1 1.3 9.6 0.3 2.6 3 0 0 3 3 3 0 Histidine kinase Spermine_synth PF01564.17 AAAP01003121.1_2 - 0.0077 15.7 0.0 0.0088 15.5 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Response_reg PF00072.24 AAAP01003122.1_2 - 3.3e-15 56.2 0.0 4.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Porphobil_deam PF01379.20 AAAP01003122.1_3 - 2.5e-12 46.8 0.0 2.9e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain ABC_membrane PF00664.23 AAAP01003123.1_1 - 3.2e-12 46.7 0.2 3.8e-12 46.4 0.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003123.1_2 - 2.7e-30 105.7 0.0 5.5e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01003123.1_2 - 6.5e-07 29.0 0.2 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 AAAP01003123.1_2 - 8.1e-05 22.8 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 AAAP01003123.1_2 - 0.00069 19.3 0.5 0.0016 18.2 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01003123.1_2 - 0.00095 19.5 0.2 0.0073 16.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01003123.1_2 - 0.0019 18.1 0.2 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 AAAP01003123.1_2 - 0.0024 17.3 0.0 0.0055 16.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.6 AAAP01003123.1_2 - 0.0099 15.5 1.1 0.022 14.3 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003123.1_2 - 0.019 15.4 2.1 0.045 14.1 2.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AAAP01003123.1_2 - 0.038 14.5 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01003123.1_2 - 0.044 14.3 0.3 0.074 13.5 0.3 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAAP01003123.1_2 - 0.052 13.8 1.1 1.3 9.3 1.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 AAAP01003123.1_2 - 0.066 12.0 0.3 5.6 5.6 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class LpxD PF04613.14 AAAP01003123.1_2 - 0.08 12.7 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD TrwB_AAD_bind PF10412.9 AAAP01003123.1_2 - 0.082 11.8 0.4 0.19 10.6 0.1 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 AAAP01003123.1_2 - 0.089 12.9 0.2 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 AAAP01003123.1_2 - 0.13 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Response_reg PF00072.24 AAAP01003123.1_3 - 1.9e-23 82.7 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003123.1_3 - 9e-18 64.1 0.0 1.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DNA_pol3_delta2 PF13177.6 AAAP01003124.1_1 - 3.5e-13 49.6 0.0 9.5e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 AAAP01003124.1_1 - 0.0051 17.2 0.0 0.0087 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAAP01003124.1_1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003124.1_1 - 0.077 13.4 0.1 0.34 11.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AAAP01003124.1_1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAAP01003124.1_1 - 0.079 12.9 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAAP01003124.1_1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAAP01003124.1_1 - 0.18 11.6 0.2 0.33 10.7 0.2 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein Thymidylate_kin PF02223.17 AAAP01003124.1_2 - 3.4e-47 160.5 0.0 3.9e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AAAP01003124.1_2 - 7.7e-07 29.5 0.0 9.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003124.1_2 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003124.1_2 - 0.031 14.6 0.2 0.062 13.7 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01003124.1_2 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAAP01003124.1_2 - 0.16 10.9 0.2 0.2 10.6 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AAAP01003124.1_2 - 0.21 12.1 0.1 0.29 11.7 0.1 1.2 1 0 0 1 1 1 0 ABC transporter Peptidase_S11 PF00768.20 AAAP01003124.1_3 - 3.8e-17 62.5 0.0 5.3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AAAP01003124.1_3 - 4.7e-16 58.8 0.0 6.6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Epimerase PF01370.21 AAAP01003125.1_1 - 5.3e-36 124.3 0.0 7.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003125.1_1 - 5.4e-33 114.8 0.0 4.7e-31 108.4 0.0 2.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AAAP01003125.1_1 - 1.6e-12 47.2 0.0 1.9e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 AAAP01003125.1_1 - 4.6e-06 25.8 0.0 3.1e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003125.1_1 - 0.00019 20.7 0.0 0.00053 19.2 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain PRP4 PF08799.11 AAAP01003125.1_1 - 0.0089 15.6 1.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 2 pre-mRNA processing factor 4 (PRP4) like B12-binding PF02310.19 AAAP01003125.1_2 - 0.0019 18.2 0.0 0.005 16.9 0.0 1.6 1 1 0 1 1 1 1 B12 binding domain SapC PF07277.11 AAAP01003126.1_1 - 1.9e-73 246.7 0.0 2.1e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 SapC Amidase PF01425.21 AAAP01003127.1_1 - 1.5e-73 248.3 1.5 1.7e-73 248.1 1.5 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 AAAP01003127.1_2 - 3.9e-21 75.1 0.2 4.8e-21 74.8 0.2 1.1 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SMI1_KNR4 PF09346.10 AAAP01003127.1_4 - 8e-07 29.5 0.0 8.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 AAAP01003127.1_4 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 AAAP01003127.1_4 - 0.00022 21.6 0.0 0.00028 21.3 0.0 1.2 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall ALGX PF16822.5 AAAP01003128.1_3 - 3.6e-05 23.6 0.0 8e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX KGG PF10685.9 AAAP01003129.1_3 - 4.6e-14 52.1 3.6 6.8e-07 29.4 0.5 2.2 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif MarR PF01047.22 AAAP01003129.1_4 - 4e-19 68.3 0.0 6.2e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01003129.1_4 - 7.2e-18 64.2 0.5 7.2e-18 64.2 0.5 2.1 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 AAAP01003129.1_4 - 5e-09 36.5 0.0 9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAAP01003129.1_4 - 1.7e-08 33.9 0.0 3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAAP01003129.1_4 - 4.4e-06 26.4 0.2 9.2e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AAAP01003129.1_4 - 5.8e-06 26.3 0.4 1.6e-05 24.8 0.3 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAAP01003129.1_4 - 8.9e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 AAAP01003129.1_4 - 5.2e-05 23.4 0.0 8.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AAAP01003129.1_4 - 0.0021 18.0 1.2 0.0071 16.3 0.4 2.2 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AAAP01003129.1_4 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family B-block_TFIIIC PF04182.12 AAAP01003129.1_4 - 0.0079 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_31 PF13560.6 AAAP01003129.1_4 - 0.028 14.7 1.2 0.059 13.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAAP01003129.1_4 - 0.028 13.9 0.1 0.064 12.8 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4423 PF14394.6 AAAP01003129.1_4 - 0.035 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Fe_dep_repress PF01325.19 AAAP01003129.1_4 - 0.086 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AAAP01003129.1_4 - 0.11 12.8 0.1 0.5 10.7 0.0 2.0 3 0 0 3 3 2 0 Transcriptional regulator HTH_3 PF01381.22 AAAP01003129.1_4 - 0.13 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_37 PF13744.6 AAAP01003129.1_4 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 AAAP01003130.1_1 - 3.3e-40 136.8 0.0 4.2e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01003130.1_1 - 4e-05 23.3 0.6 0.00023 20.8 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.18 AAAP01003130.1_1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain KAsynt_C_assoc PF16197.5 AAAP01003130.1_1 - 0.032 14.7 0.0 0.09 13.2 0.0 1.8 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Mg_chelatase PF01078.21 AAAP01003131.1_1 - 3.5e-91 304.2 0.0 5.2e-91 303.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 AAAP01003131.1_1 - 4.5e-27 94.5 4.1 1.2e-26 93.1 4.2 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal ChlI PF13541.6 AAAP01003131.1_1 - 3.5e-11 43.0 0.1 5.8e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 AAAP01003131.1_1 - 6.4e-11 42.4 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAAP01003131.1_1 - 3.1e-07 29.7 0.0 4.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 AAAP01003131.1_1 - 6.9e-06 25.9 0.0 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_32 PF13654.6 AAAP01003131.1_1 - 0.023 13.5 0.1 0.37 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 AAAP01003131.1_1 - 0.03 14.7 0.0 0.093 13.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAAP01003131.1_1 - 0.041 13.6 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AAAP01003131.1_1 - 0.051 14.0 0.7 0.21 11.9 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 AAAP01003131.1_1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0093 PF03653.13 AAAP01003132.1_1 - 0.0034 17.6 0.2 0.0034 17.6 0.2 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) DUF5325 PF17259.2 AAAP01003132.1_1 - 0.2 11.6 0.3 0.2 11.6 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Trp_oprn_chp PF09534.10 AAAP01003132.1_1 - 2.4 7.9 16.3 0.5 10.1 12.2 1.7 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Oxidored_molyb PF00174.19 AAAP01003132.1_2 - 4.8e-31 107.7 0.0 5.9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 AAAP01003132.1_3 - 8e-13 48.6 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 AAAP01003132.1_3 - 2e-08 34.8 0.0 2.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cytochrome_CBB3 PF13442.6 AAAP01003133.1_1 - 2e-22 79.3 5.2 5.8e-11 42.6 0.0 3.8 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003133.1_1 - 5.5e-22 78.7 0.0 9e-08 33.2 0.1 3.7 3 1 0 3 3 3 3 Cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003133.1_1 - 0.00036 20.2 3.2 1.3 8.8 0.1 3.3 3 0 0 3 3 3 2 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AAAP01003133.1_1 - 0.0019 18.2 0.1 16 5.6 0.0 3.3 3 0 0 3 3 3 1 Cytochrome c7 and related cytochrome c DUF1018 PF06252.12 AAAP01003133.1_1 - 0.16 12.9 0.0 1.9 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) CCP_MauG PF03150.14 AAAP01003133.1_1 - 0.47 11.1 3.2 9.2 6.9 0.0 3.2 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase NAD_binding_2 PF03446.15 AAAP01003133.1_2 - 6.8e-42 143.3 0.0 8e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01003133.1_2 - 6e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 AAAP01003133.1_2 - 3e-05 24.2 0.1 6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AAAP01003133.1_2 - 0.00028 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAAP01003133.1_2 - 0.00035 20.5 0.1 0.00043 20.2 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAAP01003133.1_2 - 0.0018 19.1 0.0 0.003 18.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AAAP01003133.1_2 - 0.0043 17.3 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AAAP01003133.1_2 - 0.007 16.3 0.1 0.013 15.4 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 AAAP01003133.1_2 - 0.012 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AAAP01003133.1_2 - 0.017 15.2 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AAAP01003133.1_2 - 0.089 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SASP PF00269.20 AAAP01003133.1_2 - 0.48 10.5 1.5 2.9 8.0 0.7 2.3 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type MCD_N PF17408.2 AAAP01003134.1_1 - 0.015 15.5 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain MCD_N PF17408.2 AAAP01003134.1_2 - 5e-21 74.6 0.1 1e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain MFS_1 PF07690.16 AAAP01003134.1_4 - 1.7e-06 27.2 17.7 1.9e-06 27.1 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01003134.1_4 - 1.7e-05 23.9 3.4 2.2e-05 23.5 3.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Promethin PF16015.5 AAAP01003134.1_4 - 0.046 13.7 6.9 0.074 13.0 6.9 1.3 1 0 0 1 1 1 0 Promethin MoaE PF02391.17 AAAP01003135.1_1 - 2e-33 115.0 0.2 2.4e-33 114.8 0.2 1.1 1 0 0 1 1 1 1 MoaE protein AI-2E_transport PF01594.16 AAAP01003135.1_2 - 3.6e-38 131.5 19.9 2.1e-35 122.4 14.6 2.0 2 0 0 2 2 2 2 AI-2E family transporter Pro_CA PF00484.19 AAAP01003135.1_3 - 2.1e-07 31.4 0.0 2.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Capsule_synth PF05159.14 AAAP01003137.1_1 - 7e-06 25.7 0.0 9.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein Capsule_synth PF05159.14 AAAP01003137.1_2 - 9.3e-41 140.3 0.0 1.1e-40 140.0 0.0 1.1 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein HlyD_3 PF13437.6 AAAP01003138.1_1 - 9.5e-18 64.9 6.2 5.5e-15 56.0 0.4 3.3 4 0 0 4 4 4 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003138.1_1 - 1.2e-13 50.7 4.5 2e-08 33.8 0.7 2.4 2 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAAP01003138.1_1 - 8.7e-11 41.6 2.4 1.9e-10 40.5 2.4 1.9 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003138.1_1 - 1.5e-10 40.7 3.3 3.2e-09 36.5 1.1 3.6 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003138.1_1 - 0.0015 18.3 0.4 0.042 13.7 0.1 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme PspA_IM30 PF04012.12 AAAP01003138.1_1 - 0.019 14.6 6.3 0.36 10.4 0.7 2.6 2 1 0 2 2 2 0 PspA/IM30 family TSC22 PF01166.18 AAAP01003138.1_1 - 0.039 14.3 0.1 0.64 10.4 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 AAAP01003138.1_1 - 0.21 11.6 4.0 0.95 9.5 1.0 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PilJ PF13675.6 AAAP01003138.1_1 - 0.48 10.5 8.8 0.2 11.7 1.0 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Filament PF00038.21 AAAP01003138.1_1 - 0.53 9.8 7.7 0.71 9.4 5.5 1.9 1 1 1 2 2 2 0 Intermediate filament protein FliT PF05400.13 AAAP01003138.1_1 - 0.74 10.7 12.4 0.21 12.4 2.2 2.8 3 0 0 3 3 3 0 Flagellar protein FliT Atg14 PF10186.9 AAAP01003138.1_1 - 0.76 8.8 2.9 0.72 8.9 0.9 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 AAAP01003138.1_1 - 5.8 7.0 6.6 8.5 6.5 0.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.11 AAAP01003138.1_1 - 7.3 6.7 10.7 1.1 9.4 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FUSC PF04632.12 AAAP01003138.1_1 - 8.5 4.8 12.2 0.76 8.2 6.8 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Ribosomal_L36 PF00444.18 AAAP01003138.1_2 - 9.5e-15 54.5 3.4 1.3e-14 54.1 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 TPR_2 PF07719.17 AAAP01003138.1_3 - 7.8e-13 47.5 6.9 4e-05 23.4 1.6 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003138.1_3 - 7.8e-11 41.3 0.3 0.0012 18.6 0.6 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003138.1_3 - 5.7e-08 33.3 16.0 1.5e-07 32.0 7.8 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003138.1_3 - 4.8e-07 30.1 18.0 4.9e-05 23.8 1.3 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003138.1_3 - 1.7e-06 28.0 1.0 0.0019 18.5 0.0 3.3 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003138.1_3 - 2.5e-06 27.1 0.1 0.00024 20.7 0.1 2.9 3 0 0 3 3 3 1 TPR repeat ChAPs PF09295.10 AAAP01003138.1_3 - 4.5e-06 25.9 0.0 0.0064 15.6 0.0 2.0 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 AAAP01003138.1_3 - 1.1e-05 25.3 0.4 0.33 11.3 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003138.1_3 - 0.00019 21.5 13.7 0.0024 18.0 5.6 3.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003138.1_3 - 0.002 18.6 6.7 0.18 12.5 0.9 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003138.1_3 - 0.0024 18.3 8.6 0.0066 16.9 2.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat BAALC_N PF06989.12 AAAP01003138.1_3 - 0.014 15.7 1.5 3.4 8.1 0.4 2.6 1 1 1 2 2 2 0 BAALC N-terminus TPR_7 PF13176.6 AAAP01003138.1_3 - 0.019 15.0 0.3 7.5 6.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PspA_IM30 PF04012.12 AAAP01003138.1_3 - 0.02 14.4 0.3 0.036 13.6 0.3 1.3 1 0 0 1 1 1 0 PspA/IM30 family TPR_12 PF13424.6 AAAP01003138.1_3 - 0.025 14.9 7.7 0.026 14.8 2.2 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003138.1_3 - 0.045 13.1 2.5 1.1 8.6 0.2 2.6 1 1 1 2 2 2 0 MalT-like TPR region Abhydrolase_1 PF00561.20 AAAP01003138.1_4 - 0.018 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 AAAP01003139.1_1 - 0.0098 14.8 21.9 0.011 14.7 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SLATT_1 PF18181.1 AAAP01003139.1_1 - 0.76 9.7 4.6 7.5 6.5 0.6 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3040 PF11239.8 AAAP01003139.1_1 - 8 6.8 17.8 0.062 13.6 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Trp_oprn_chp PF09534.10 AAAP01003139.1_1 - 9.4 6.0 17.7 13 5.5 17.7 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Aminotran_1_2 PF00155.21 AAAP01003139.1_2 - 3.5e-18 65.9 0.0 1.1e-17 64.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAAP01003139.1_2 - 0.002 17.1 0.0 0.0026 16.7 0.0 1.1 1 0 0 1 1 1 1 Allinase OCD_Mu_crystall PF02423.15 AAAP01003139.1_2 - 0.063 12.2 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CobD_Cbib PF03186.13 AAAP01003139.1_3 - 9.4e-42 143.1 5.3 1.1e-41 142.8 5.3 1.0 1 0 0 1 1 1 1 CobD/Cbib protein YesK PF14150.6 AAAP01003139.1_3 - 0.037 14.2 1.7 0.07 13.3 0.2 2.0 2 0 0 2 2 2 0 YesK-like protein TetR_N PF00440.23 AAAP01003140.1_1 - 1.3e-11 44.1 0.6 2.2e-11 43.4 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 AAAP01003140.1_1 - 0.033 14.3 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Lactamase_B PF00753.27 AAAP01003140.1_2 - 7.4e-22 78.3 2.3 2e-21 76.9 2.4 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01003140.1_2 - 4.4e-06 26.4 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SoxY PF13501.6 AAAP01003140.1_3 - 6.2e-32 110.1 0.0 1.1e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Sulfur oxidation protein SoxY SoxZ PF08770.11 AAAP01003140.1_3 - 1.4e-21 76.0 0.0 8.8e-21 73.5 0.0 2.2 3 0 0 3 3 3 1 Sulphur oxidation protein SoxZ HI0933_like PF03486.14 AAAP01003140.1_3 - 0.0015 17.4 0.0 0.002 16.9 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Ald_Xan_dh_C2 PF02738.18 AAAP01003141.1_1 - 4.5e-173 576.6 0.4 5.4e-173 576.4 0.4 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01003141.1_1 - 2e-07 31.3 0.0 2e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MS_channel PF00924.18 AAAP01003142.1_1 - 1.6e-21 76.9 1.2 2.8e-21 76.0 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Polysacc_synt_C PF14667.6 AAAP01003142.1_1 - 0.041 14.0 8.5 0.088 12.9 8.5 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF2975 PF11188.8 AAAP01003142.1_1 - 0.37 10.7 6.3 0.38 10.6 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4010 PF13194.6 AAAP01003142.1_1 - 0.75 9.4 13.8 1.1 8.9 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) MerC PF03203.14 AAAP01003142.1_1 - 2.6 8.5 11.4 0.27 11.7 1.3 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein Polyketide_cyc2 PF10604.9 AAAP01003143.1_1 - 6.6e-06 26.4 0.1 1.5e-05 25.3 0.0 1.6 1 1 1 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport DUF4148 PF13663.6 AAAP01003143.1_1 - 0.034 14.3 2.5 0.044 14.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) HTH_1 PF00126.27 AAAP01003143.1_1 - 0.068 13.1 0.6 0.077 13.0 0.6 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Polyketide_cyc2 PF10604.9 AAAP01003143.1_2 - 5.3e-27 94.8 0.5 7.5e-27 94.3 0.5 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF447 PF04289.12 AAAP01003143.1_3 - 2.2e-30 105.7 0.0 2.5e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF447) HemolysinCabind PF00353.19 AAAP01003144.1_1 - 2e-36 123.5 104.5 1.9e-11 43.7 7.2 4.7 2 1 3 5 5 5 5 RTX calcium-binding nonapeptide repeat (4 copies) Collagen PF01391.18 AAAP01003144.1_1 - 0.0064 16.2 11.4 0.17 11.6 4.5 2.7 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Rhodanese PF00581.20 AAAP01003144.1_3 - 5.1e-16 59.1 0.0 1.4e-13 51.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Epimerase PF01370.21 AAAP01003146.1_2 - 3.4e-27 95.5 0.0 3.8e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003146.1_2 - 1.1e-20 74.4 0.1 1.5e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAAP01003146.1_2 - 5.2e-13 48.8 0.9 2.6e-12 46.5 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAAP01003146.1_2 - 5.5e-12 45.3 0.0 6.8e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAAP01003146.1_2 - 8e-10 38.9 0.1 8.9e-10 38.7 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAAP01003146.1_2 - 1.4e-07 31.3 0.6 5e-07 29.5 0.6 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 AAAP01003146.1_2 - 4.5e-07 29.3 1.3 0.00033 19.9 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003146.1_2 - 5.2e-06 25.8 0.1 6.3e-06 25.5 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 AAAP01003146.1_2 - 0.0053 16.7 4.2 0.06 13.3 4.2 2.3 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 AAAP01003146.1_2 - 0.014 15.6 0.1 0.023 15.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 AAAP01003146.1_2 - 0.046 13.2 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 AAAP01003146.1_3 - 9.5e-20 71.1 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003146.1_3 - 6.8e-17 61.9 0.0 1e-16 61.3 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AAAP01003146.1_3 - 0.003 16.8 0.0 0.0041 16.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AAAP01003146.1_3 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SLT_2 PF13406.6 AAAP01003146.1_4 - 1.6e-98 329.6 0.0 1.9e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 AAAP01003146.1_4 - 0.00052 20.2 0.3 0.0015 18.7 0.1 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 AAAP01003146.1_4 - 0.028 14.7 3.7 0.48 10.8 0.1 3.5 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Glucosaminidase PF01832.20 AAAP01003146.1_4 - 0.044 14.3 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Ald_Xan_dh_C2 PF02738.18 AAAP01003147.1_1 - 5.6e-64 216.5 1.1 2e-46 158.6 0.2 2.3 2 1 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 AAAP01003147.1_2 - 1.6e-11 44.0 0.8 1.9e-11 43.8 0.0 1.5 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003147.1_2 - 2.3e-05 24.3 1.2 5.2e-05 23.1 0.1 2.0 1 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain CPSase_L_D2 PF02786.17 AAAP01003148.1_1 - 6.4e-27 94.4 0.0 7.9e-17 61.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AAAP01003148.1_1 - 4.3e-22 78.7 0.0 6.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATPgrasp_Ter PF15632.6 AAAP01003148.1_1 - 4.9e-05 23.1 0.0 0.00015 21.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 AAAP01003148.1_1 - 0.00012 21.7 0.0 0.0016 18.0 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAAP01003148.1_1 - 0.00057 20.0 0.0 0.0043 17.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Phage_portal PF04860.12 AAAP01003149.1_1 - 1.4e-40 139.5 0.0 1.5e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein Peptidase_S78 PF04586.17 AAAP01003149.1_2 - 3.2e-21 76.2 0.0 5.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Caudovirus prohead serine protease COG2 PF06148.11 AAAP01003149.1_3 - 0.078 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spore_YtfJ PF09579.10 AAAP01003149.1_3 - 0.51 10.5 3.5 0.23 11.7 0.7 1.9 2 1 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Plug PF07715.15 AAAP01003150.1_1 - 7.6e-15 55.4 3.2 7.6e-15 55.4 3.2 1.8 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain DUF2946 PF11162.8 AAAP01003150.1_2 - 0.02 15.5 6.9 0.029 15.0 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TetR_N PF00440.23 AAAP01003151.1_1 - 4.3e-07 29.6 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family adh_short PF00106.25 AAAP01003151.1_2 - 4.3e-51 173.1 0.2 5.7e-51 172.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003151.1_2 - 2.2e-38 132.2 1.0 2.7e-38 131.8 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003151.1_2 - 1.9e-11 44.2 1.4 2.9e-11 43.6 1.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003151.1_2 - 5.1e-07 29.4 0.7 1.9e-06 27.5 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01003151.1_2 - 1.3e-06 28.5 1.4 1.9e-06 27.9 1.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding ApbA_C PF08546.11 AAAP01003151.1_3 - 6.4e-17 61.9 0.0 7.3e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Glycos_transf_1 PF00534.20 AAAP01003152.1_1 - 4.6e-28 97.9 0.0 5.7e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003152.1_1 - 5.6e-25 88.3 0.0 7.8e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003152.1_1 - 1.4e-11 44.6 0.0 2.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIG-L PF02585.17 AAAP01003152.1_2 - 3.6e-21 76.2 0.0 2.5e-20 73.4 0.0 2.0 1 1 1 2 2 2 1 GlcNAc-PI de-N-acetylase GTA_TIM PF13547.6 AAAP01003154.1_1 - 9.5e-108 360.0 0.0 1.3e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 GTA TIM-barrel-like domain Phage-tail_3 PF13550.6 AAAP01003154.1_1 - 2e-39 135.1 2.1 2e-39 135.1 2.1 2.2 2 0 0 2 2 2 1 Putative phage tail protein 2OG-FeII_Oxy_2 PF13532.6 AAAP01003154.1_1 - 0.095 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2793 PF10983.8 AAAP01003154.1_2 - 4.4e-28 97.0 1.4 4.6e-28 96.9 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2793) DUF1853 PF08907.11 AAAP01003154.1_2 - 0.053 13.2 0.3 0.058 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) HTH_11 PF08279.12 AAAP01003155.1_1 - 5.4e-13 48.7 0.0 9.1e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 AAAP01003155.1_1 - 0.0015 18.6 2.1 0.002 18.2 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAAP01003155.1_1 - 0.004 17.6 0.1 0.0069 16.9 0.1 1.4 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 WYL PF13280.6 AAAP01003155.1_1 - 0.049 13.7 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 WYL domain GST_N_3 PF13417.6 AAAP01003155.1_2 - 1.4e-09 38.2 0.0 2.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAAP01003155.1_2 - 2.2e-07 31.0 0.0 1.1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAAP01003155.1_2 - 1.2e-05 25.6 0.0 2.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003155.1_2 - 1.7e-05 24.8 1.6 3.4e-05 23.8 0.8 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AAAP01003155.1_2 - 4.6e-05 23.6 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 AAAP01003155.1_2 - 0.0042 17.8 0.0 0.0066 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 AAAP01003155.1_2 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AAAP01003155.1_2 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RecA PF00154.21 AAAP01003155.1_3 - 6.6e-49 166.7 0.2 8.1e-49 166.4 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PNP_UDP_1 PF01048.20 AAAP01003156.1_2 - 4.2e-46 157.1 2.3 4.9e-46 156.9 2.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DeoC PF01791.9 AAAP01003156.1_3 - 2.3e-30 105.9 0.1 2.9e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase CheR PF01739.18 AAAP01003157.1_1 - 8.3e-44 149.4 0.0 1.3e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Spc7 PF08317.11 AAAP01003157.1_1 - 0.0011 17.9 8.9 0.0016 17.4 8.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein OmpH PF03938.14 AAAP01003157.1_1 - 0.0096 16.3 3.8 0.021 15.2 3.8 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 AAAP01003157.1_1 - 0.015 15.6 5.7 0.029 14.6 5.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.8 AAAP01003157.1_1 - 0.021 14.4 7.1 0.035 13.8 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4855 PF16147.5 AAAP01003157.1_1 - 0.023 13.8 0.5 0.041 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) BLOC1_2 PF10046.9 AAAP01003157.1_1 - 0.041 14.2 2.6 0.68 10.3 3.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Methyltransf_25 PF13649.6 AAAP01003157.1_1 - 0.047 14.4 0.1 6.3 7.6 0.1 2.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003157.1_1 - 0.052 14.3 0.0 7.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain DUF16 PF01519.16 AAAP01003157.1_1 - 0.058 13.9 1.4 0.13 12.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF812 PF05667.11 AAAP01003157.1_1 - 0.061 12.2 7.4 0.081 11.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cytochrom_C_2 PF01322.20 AAAP01003157.1_1 - 0.072 14.0 2.9 0.14 13.1 2.9 1.5 1 0 0 1 1 1 0 Cytochrome C' UPF0449 PF15136.6 AAAP01003157.1_1 - 0.077 13.5 3.5 0.19 12.2 3.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Methyltransf_31 PF13847.6 AAAP01003157.1_1 - 0.08 12.7 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DUF1664 PF07889.12 AAAP01003157.1_1 - 0.13 12.3 0.8 0.24 11.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SesA PF17107.5 AAAP01003157.1_1 - 0.17 12.1 1.7 0.35 11.0 1.7 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Lebercilin PF15619.6 AAAP01003157.1_1 - 0.39 10.4 10.5 0.96 9.1 6.1 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 AAAP01003157.1_1 - 0.42 11.1 12.1 0.69 10.4 12.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 AAAP01003157.1_1 - 0.59 10.3 15.3 0.28 11.4 11.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 AAAP01003157.1_1 - 1 9.8 10.3 0.23 11.9 7.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) UPF0242 PF06785.11 AAAP01003157.1_1 - 2.3 8.3 7.6 3.6 7.7 7.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 AAAP01003157.1_1 - 2.6 8.5 13.1 6.1 7.4 12.9 1.8 1 1 1 2 2 2 0 Cell division protein ZapB DUF4140 PF13600.6 AAAP01003157.1_1 - 8.3 6.9 9.0 31 5.1 9.0 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2470 PF10615.9 AAAP01003158.1_2 - 4.4e-14 52.9 0.0 7.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 AAAP01003158.1_2 - 3.1e-13 50.1 0.0 5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 AAAP01003158.1_2 - 1.4e-11 44.4 0.0 4e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Condensation PF00668.20 AAAP01003159.1_2 - 8.8e-48 163.1 0.0 1.2e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain DUF444 PF04285.12 AAAP01003160.1_1 - 5.1e-152 506.8 0.0 6.3e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) VWA_CoxE PF05762.14 AAAP01003160.1_1 - 0.16 11.3 2.6 0.84 9.0 0.3 2.6 2 1 1 3 3 3 0 VWA domain containing CoxE-like protein SpoVR PF04293.13 AAAP01003160.1_2 - 1.4e-62 211.8 0.5 1.5e-62 211.6 0.5 1.0 1 0 0 1 1 1 1 SpoVR like protein AMP-binding PF00501.28 AAAP01003161.1_1 - 1.8e-36 125.7 0.0 2.2e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 AAAP01003161.1_2 - 5.4e-35 120.8 0.0 7.2e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003161.1_2 - 1.9e-07 32.0 0.9 3.1e-07 31.3 0.9 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Endotoxin_C PF03944.14 AAAP01003161.1_2 - 0.15 12.4 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin HemolysinCabind PF00353.19 AAAP01003162.1_1 - 2.6e-49 164.7 190.2 7.4e-08 32.2 21.1 12.7 11 3 2 13 13 13 12 RTX calcium-binding nonapeptide repeat (4 copies) cNMP_binding PF00027.29 AAAP01003163.1_1 - 1.8e-11 43.9 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Trans_reg_C PF00486.28 AAAP01003163.1_2 - 1.7e-22 79.3 0.6 2.7e-21 75.4 0.1 2.5 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01003163.1_2 - 3.3e-20 72.3 0.0 6.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain TonB_dep_Rec PF00593.24 AAAP01003164.1_1 - 1.1e-31 111.2 10.5 1.4e-31 110.9 10.5 1.0 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AAAP01003164.1_1 - 0.014 14.4 0.0 0.15 11.0 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein beta-barrel family Acatn PF13000.7 AAAP01003164.1_1 - 0.024 13.1 0.2 0.033 12.7 0.2 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 ABC_membrane PF00664.23 AAAP01003164.1_3 - 0.0042 16.8 0.0 0.0052 16.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region CN_hydrolase PF00795.22 AAAP01003165.1_1 - 1.8e-11 43.9 0.0 2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2474 PF10617.9 AAAP01003165.1_2 - 4.2e-09 36.1 8.5 5.3e-09 35.8 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) Cyt_bd_oxida_II PF02322.15 AAAP01003165.1_3 - 6.1e-97 324.6 36.0 6.9e-97 324.5 36.0 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Cyt_bd_oxida_I PF01654.17 AAAP01003165.1_4 - 1.4e-53 182.1 2.6 1.5e-53 181.9 2.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF2157 PF09925.9 AAAP01003165.1_4 - 0.18 11.6 6.7 0.32 10.8 6.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DctP PF03480.13 AAAP01003166.1_1 - 1.6e-25 90.0 0.0 2e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 GRDA PF04723.14 AAAP01003166.1_1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.5 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A DSPc PF00782.20 AAAP01003166.1_2 - 0.0005 19.9 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AAAP01003166.1_2 - 0.024 14.2 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 AAAP01003166.1_2 - 0.15 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Phe_tRNA-synt_N PF02912.18 AAAP01003166.1_2 - 0.17 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Trans_reg_C PF00486.28 AAAP01003167.1_1 - 1e-15 57.6 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Phosphatase PF15698.5 AAAP01003167.1_1 - 0.049 12.8 0.0 0.059 12.5 0.0 1.0 1 0 0 1 1 1 0 Phosphatase HATPase_c PF02518.26 AAAP01003167.1_2 - 1.6e-17 64.0 0.0 3.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003167.1_2 - 3.5e-05 23.7 0.8 0.00036 20.5 0.8 2.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003167.1_2 - 0.0055 17.0 6.2 0.0098 16.3 0.2 3.7 3 1 1 4 4 4 1 HAMP domain HATPase_c_2 PF13581.6 AAAP01003167.1_2 - 0.013 15.5 0.1 0.09 12.7 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Serine_rich PF08824.10 AAAP01003167.1_2 - 0.088 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain HATPase_c_3 PF13589.6 AAAP01003167.1_2 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPW PF03779.14 AAAP01003168.1_1 - 1.9e-26 91.4 38.7 1.2e-16 60.0 20.1 2.0 2 0 0 2 2 2 2 SPW repeat DUF4818 PF16089.5 AAAP01003168.1_1 - 0.0047 17.4 7.3 0.15 12.5 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4818) YfhO PF09586.10 AAAP01003168.1_1 - 1.9 6.6 5.8 2.3 6.3 5.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4079 PF13301.6 AAAP01003168.1_1 - 6.4 6.9 11.5 13 6.0 11.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Phage_holin_5_2 PF16079.5 AAAP01003168.1_1 - 8.9 6.7 11.9 1.1 9.6 1.4 2.1 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Trypsin_2 PF13365.6 AAAP01003168.1_2 - 2.4e-32 112.9 3.2 4.5e-32 112.0 3.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAAP01003168.1_2 - 6.8e-28 96.8 6.5 8.7e-18 64.4 0.2 3.3 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 AAAP01003168.1_2 - 2.2e-26 91.5 7.9 5e-13 48.7 0.5 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AAAP01003168.1_2 - 2.9e-25 88.4 1.4 4.5e-12 46.1 0.1 3.5 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AAAP01003168.1_2 - 8.3e-17 61.7 0.3 1.8e-16 60.6 0.3 1.5 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AAAP01003168.1_2 - 1.2e-09 38.0 1.4 0.00054 19.9 0.1 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 AAAP01003168.1_2 - 2.8e-05 24.5 0.0 0.042 14.2 0.0 2.5 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain LSM PF01423.22 AAAP01003168.1_2 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 LSM domain TOBE_3 PF12857.7 AAAP01003168.1_2 - 0.028 14.3 0.3 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 TOBE-like domain DUF3394 PF11874.8 AAAP01003168.1_2 - 0.12 12.0 0.0 19 4.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3394) Peptidase_S46 PF10459.9 AAAP01003168.1_2 - 0.18 10.4 0.9 11 4.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 DUF4537 PF15057.6 AAAP01003168.1_2 - 0.22 11.5 0.1 10 6.1 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4537) FtsH_ext PF06480.15 AAAP01003168.1_3 - 5.5e-09 36.3 0.7 1.6e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular TetR_N PF00440.23 AAAP01003169.1_1 - 1.9e-18 66.0 0.2 4.3e-18 64.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 AAAP01003169.1_1 - 0.00022 21.1 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_AsnC-type PF13404.6 AAAP01003169.1_1 - 0.0055 16.5 0.3 0.24 11.3 0.0 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003169.1_1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DIX PF00778.17 AAAP01003169.1_1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 DIX domain HTH_20 PF12840.7 AAAP01003169.1_1 - 0.046 13.8 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003169.1_1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_1_2 PF13022.6 AAAP01003169.1_1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase YCII PF03795.14 AAAP01003169.1_2 - 6.2e-06 26.5 0.0 7.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Adenine_glyco PF03352.13 AAAP01003169.1_3 - 2.2e-70 236.0 0.0 2.5e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HTH_21 PF13276.6 AAAP01003169.1_3 - 0.0064 16.6 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 2 HTH-like domain AAA_30 PF13604.6 AAAP01003170.1_1 - 1.9e-49 168.0 9.7 1.9e-49 168.0 9.7 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAAP01003170.1_1 - 5.3e-11 43.1 1.3 8.3e-11 42.4 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 AAAP01003170.1_1 - 7.6e-06 25.9 0.1 0.054 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAAP01003170.1_1 - 7.7e-05 22.5 0.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 AAAP01003170.1_1 - 8.8e-05 21.8 0.0 0.00041 19.6 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase PhoH PF02562.16 AAAP01003170.1_1 - 0.00023 20.7 0.1 0.22 10.9 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD_C_2 PF13538.6 AAAP01003170.1_1 - 0.03 14.2 0.5 0.076 12.9 0.5 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4350 PF14258.6 AAAP01003170.1_1 - 0.03 14.7 2.3 0.1 13.1 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4350) DUF2065 PF09838.9 AAAP01003170.1_1 - 0.091 12.8 0.7 0.38 10.8 0.7 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) UvrD-helicase PF00580.21 AAAP01003170.1_1 - 0.24 10.9 0.5 0.4 10.2 0.5 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Toprim_4 PF13662.6 AAAP01003171.1_1 - 7.8e-24 84.0 0.1 1.2e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 AAAP01003171.1_1 - 5.2e-12 45.1 3.3 9.9e-12 44.2 3.3 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AAAP01003171.1_1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Toprim domain PEPCK_ATP PF01293.20 AAAP01003171.1_2 - 2.5e-118 395.7 0.0 3.1e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase CPBP PF02517.16 AAAP01003172.1_1 - 1.1e-15 57.7 6.4 1.1e-15 57.7 6.4 2.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease CcmH PF03918.14 AAAP01003172.1_1 - 3.4 6.9 4.3 6 6.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Thymidylat_synt PF00303.19 AAAP01003172.1_2 - 1.2e-122 408.2 0.0 1.4e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase MutS_I PF01624.20 AAAP01003173.1_1 - 1.9e-42 144.1 0.0 2.5e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 AAAP01003173.1_1 - 2.7e-23 82.8 0.0 4.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain II EamA PF00892.20 AAAP01003174.1_1 - 2.8e-19 69.6 34.3 6e-11 42.7 18.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 AAAP01003174.1_1 - 1.3 8.1 6.1 2.1 7.4 6.1 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Bacteriocin_IIc PF10439.9 AAAP01003174.1_2 - 0.0059 16.7 11.0 0.0077 16.3 11.0 1.3 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide MccV PF17508.2 AAAP01003174.1_2 - 0.19 12.3 4.2 0.23 12.0 4.2 1.1 1 0 0 1 1 1 0 Microcin V bacteriocin Gly-zipper_Omp PF13488.6 AAAP01003174.1_2 - 0.2 11.7 15.6 0.34 11.0 15.6 1.4 1 0 0 1 1 1 0 Glycine zipper Glycos_transf_2 PF00535.26 AAAP01003175.1_1 - 4.5e-08 33.1 0.0 6.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAAP01003175.1_1 - 3.4e-07 29.9 0.0 6.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 AAAP01003175.1_1 - 0.00076 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003175.1_1 - 0.002 18.1 0.0 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MdoG PF04349.12 AAAP01003175.1_2 - 1.3e-17 63.9 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG ATP-synt_ab PF00006.25 AAAP01003177.1_1 - 4.3e-64 216.1 0.0 5.7e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAAP01003177.1_1 - 1.2e-15 57.1 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ABC_tran PF00005.27 AAAP01003177.1_1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 AAAP01003177.1_1 - 0.012 15.6 0.2 0.039 13.9 0.1 1.7 1 1 1 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 AAAP01003177.1_1 - 0.099 12.2 3.6 0.16 11.5 1.4 2.4 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 AAAP01003177.1_1 - 0.29 11.2 0.3 0.48 10.5 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain FlaE PF07559.14 AAAP01003177.1_2 - 4.8e-10 40.1 1.0 1.2e-09 38.8 0.4 1.9 2 0 0 2 2 2 1 Flagellar basal body protein FlaE Flg_bb_rod PF00460.20 AAAP01003177.1_2 - 9.1e-10 38.3 2.7 9.1e-10 38.3 2.7 2.0 2 0 0 2 2 2 1 Flagella basal body rod protein DUF5627 PF18620.1 AAAP01003177.1_2 - 0.054 13.4 1.3 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5627) OMP_b-brl PF13505.6 AAAP01003178.1_1 - 8.1e-09 35.9 23.3 3.5e-08 33.8 23.3 2.1 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain Thioredoxin PF00085.20 AAAP01003178.1_2 - 3.6e-27 94.4 0.0 3.9e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AAAP01003178.1_2 - 1.4e-07 31.8 0.0 2.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAAP01003178.1_2 - 2e-07 31.4 0.0 8.1e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 AAAP01003178.1_2 - 1.6e-05 24.7 0.0 1.8e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 AAAP01003178.1_2 - 5.3e-05 23.2 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 AAAP01003178.1_2 - 0.00087 18.7 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 AAAP01003178.1_2 - 0.0022 17.7 0.0 0.23 11.1 0.0 2.0 1 1 1 2 2 2 2 Redoxin DUF836 PF05768.14 AAAP01003178.1_2 - 0.0041 17.5 0.0 0.0041 17.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.21 AAAP01003178.1_2 - 0.0089 15.9 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 AAAP01003178.1_2 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DIM1 PF02966.16 AAAP01003178.1_2 - 0.018 14.8 0.0 0.018 14.8 0.0 1.0 1 0 0 1 1 1 0 Mitosis protein DIM1 HyaE PF07449.11 AAAP01003178.1_2 - 0.033 14.2 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 AAAP01003178.1_2 - 0.048 13.6 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain KaiB PF07689.12 AAAP01003178.1_2 - 0.048 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiB domain TrbC_Ftype PF09673.10 AAAP01003178.1_2 - 0.081 13.0 0.0 0.086 12.9 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein adh_short PF00106.25 AAAP01003179.1_1 - 4.3e-28 98.1 0.0 5.5e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003179.1_1 - 3.3e-17 62.8 0.1 4.3e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003179.1_1 - 1.4e-09 38.2 0.1 1.8e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1177 PF06675.11 AAAP01003179.1_1 - 0.078 11.8 0.7 0.11 11.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) FAD_binding_4 PF01565.23 AAAP01003179.1_2 - 6.2e-15 55.2 0.0 1.6e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thioesterase PF00975.20 AAAP01003180.1_2 - 6.3e-29 101.7 0.0 8e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 AAAP01003180.1_2 - 0.00015 21.5 0.0 0.032 13.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 AAAP01003180.1_2 - 0.034 14.0 0.1 0.054 13.3 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 AAAP01003180.1_2 - 0.055 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 AAAP01003180.1_2 - 0.14 11.4 0.0 9.6 5.4 0.0 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAAP01003180.1_3 - 3.7e-28 99.2 0.0 4.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AAAP01003180.1_3 - 0.00012 22.8 9.7 0.00015 22.4 9.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01003180.1_3 - 0.0079 15.5 0.0 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 AAAP01003180.1_3 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 AAAP01003180.1_3 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF726 PF05277.12 AAAP01003180.1_3 - 0.29 10.0 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Biotin_lipoyl_2 PF13533.6 AAAP01003180.1_4 - 2.9e-10 39.8 0.6 4.7e-10 39.1 0.6 1.2 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003180.1_4 - 0.01 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Biotin-requiring enzyme HlyD_D23 PF16576.5 AAAP01003180.1_4 - 0.061 12.5 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion LPMO_10 PF03067.15 AAAP01003181.1_1 - 9.2e-05 23.2 0.2 0.0003 21.5 0.0 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_5_12 PF02839.14 AAAP01003181.1_1 - 0.0011 19.5 9.0 0.0011 19.5 9.0 3.7 3 1 0 3 3 3 1 Carbohydrate binding domain S4 PF01479.25 AAAP01003181.1_2 - 4e-13 48.9 0.2 6.6e-13 48.1 0.2 1.4 1 0 0 1 1 1 1 S4 domain Transgly_assoc PF04226.13 AAAP01003181.1_3 - 1.4e-10 41.3 9.9 1.4e-10 41.3 9.9 2.2 1 1 1 2 2 2 1 Transglycosylase associated protein Rick_17kDa_Anti PF05433.15 AAAP01003181.1_3 - 0.16 11.8 9.5 0.074 12.9 2.4 2.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain UPF0126 PF03458.13 AAAP01003181.1_3 - 0.22 11.4 9.6 0.4 10.6 9.6 1.4 1 1 0 1 1 1 0 UPF0126 domain Tmemb_170 PF10190.9 AAAP01003181.1_3 - 0.35 11.3 5.3 0.83 10.0 5.3 1.6 1 1 0 1 1 1 0 Putative transmembrane protein 170 DUF1129 PF06570.11 AAAP01003181.1_3 - 0.36 10.3 3.1 0.4 10.2 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) LGT PF01790.18 AAAP01003181.1_3 - 0.56 9.4 6.9 0.62 9.3 6.9 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF4191 PF13829.6 AAAP01003181.1_3 - 0.65 9.3 3.3 0.38 10.1 1.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) FecCD PF01032.18 AAAP01003181.1_3 - 0.69 8.9 10.5 0.44 9.5 5.5 1.9 1 1 1 2 2 2 0 FecCD transport family CRCB PF02537.15 AAAP01003181.1_3 - 0.85 10.0 6.0 2.2 8.7 6.0 1.7 1 1 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) FeoB_C PF07664.12 AAAP01003181.1_3 - 1.6 8.5 10.4 1.6 8.5 0.7 3.0 2 1 1 3 3 3 0 Ferrous iron transport protein B C terminus YIEGIA PF14045.6 AAAP01003181.1_3 - 3.4 6.4 4.3 2.9 6.7 2.6 1.7 1 1 1 2 2 2 0 YIEGIA protein OHCU_decarbox PF09349.10 AAAP01003182.1_1 - 1.1e-40 139.6 0.2 1.5e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Transthyretin PF00576.21 AAAP01003182.1_1 - 1.6e-26 93.2 0.0 2.7e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 AAAP01003182.1_1 - 0.0039 17.4 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Xan_ur_permease PF00860.20 AAAP01003182.1_2 - 1.1e-86 291.1 36.5 1.3e-86 290.8 36.5 1.0 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 AAAP01003182.1_3 - 1.3e-07 30.7 5.0 1.3e-07 30.7 5.0 1.9 1 1 1 2 2 2 2 Permease family MatE PF01554.18 AAAP01003182.1_3 - 0.17 11.5 4.2 0.21 11.2 4.2 1.1 1 0 0 1 1 1 0 MatE adh_short PF00106.25 AAAP01003183.1_1 - 2.7e-53 180.3 0.0 4e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003183.1_1 - 1.3e-46 159.1 0.0 2e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003183.1_1 - 1.2e-09 38.4 0.1 6.2e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 AAAP01003183.1_1 - 0.0023 17.3 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ACCA PF03255.14 AAAP01003183.1_2 - 5.8e-58 194.8 0.0 8.4e-58 194.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AAAP01003183.1_2 - 1.3e-17 63.6 1.8 1.9e-17 63.1 1.8 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAAP01003183.1_2 - 0.0015 18.1 1.5 0.0023 17.5 1.5 1.3 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 AAAP01003183.1_2 - 0.0031 16.8 0.7 0.005 16.2 0.7 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3717 PF12512.8 AAAP01003183.1_2 - 0.087 12.7 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Biotin_lipoyl_2 PF13533.6 AAAP01003184.1_1 - 9.5e-09 35.0 4.2 1.1e-08 34.7 1.0 2.4 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.7 AAAP01003184.1_1 - 0.018 13.8 0.1 0.022 13.5 0.1 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAAP01003184.1_1 - 0.038 13.8 0.3 2.1 8.2 0.0 2.3 1 1 1 2 2 2 0 Biotin-requiring enzyme TetR_N PF00440.23 AAAP01003184.1_2 - 3e-16 58.9 0.0 6.8e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 AAAP01003184.1_2 - 1.7e-11 44.3 1.7 4.8e-11 42.9 1.7 1.7 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 AAAP01003184.1_2 - 4.6e-10 39.7 1.7 4.6e-10 39.7 1.7 2.7 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain DUF4866 PF16160.5 AAAP01003184.1_2 - 0.087 12.1 0.0 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4866) Imp-YgjV PF10688.9 AAAP01003184.1_4 - 3.8e-37 127.5 8.4 4.8e-37 127.2 8.4 1.1 1 0 0 1 1 1 1 Bacterial inner membrane protein ABC_tran PF00005.27 AAAP01003184.1_5 - 6.1e-17 62.4 0.0 7.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 AAAP01003184.1_5 - 3.2e-06 27.8 0.0 3.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003184.1_5 - 7.5e-06 25.6 0.1 9e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003184.1_5 - 0.00038 20.4 0.1 0.00041 20.3 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AAAP01003184.1_5 - 0.0032 17.3 0.1 0.0034 17.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 AAAP01003184.1_5 - 0.0086 15.4 0.0 0.0092 15.3 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 AAAP01003184.1_5 - 0.017 15.2 0.2 0.027 14.6 0.2 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01003184.1_5 - 0.023 14.1 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 AAAP01003184.1_5 - 0.025 15.0 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01003184.1_5 - 0.025 15.0 0.0 0.027 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01003184.1_5 - 0.045 13.1 0.1 0.047 13.1 0.1 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 AAAP01003184.1_5 - 0.046 13.6 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 AAAP01003184.1_5 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 AAAP01003184.1_5 - 0.17 11.4 0.0 0.31 10.5 0.0 1.6 1 1 0 1 1 1 0 P-loop Nucleotide Kinase1 NTPase_1 PF03266.15 AAAP01003184.1_5 - 0.17 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 AAAP01003184.1_5 - 0.18 11.8 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 AAAP01003184.1_5 - 0.21 11.3 0.1 0.22 11.2 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain RNA_pol_Rpb2_6 PF00562.28 AAAP01003185.1_1 - 3.5e-41 141.6 0.0 2.3e-40 138.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 AAAP01003185.1_1 - 2.1e-33 114.3 0.0 3.7e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_45 PF10385.9 AAAP01003185.1_1 - 1.1e-24 86.4 0.2 2.6e-24 85.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_1 PF04563.15 AAAP01003185.1_1 - 6.8e-06 25.7 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit tRNA-synt_2c PF01411.19 AAAP01003186.1_1 - 1.7e-190 634.2 0.0 1.9e-190 634.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) P5CR_dimer PF14748.6 AAAP01003187.1_1 - 5.3e-33 113.4 5.1 8.7e-33 112.7 5.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AAAP01003187.1_1 - 4.3e-08 33.6 0.0 1.3e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NMT1_2 PF13379.6 AAAP01003187.1_1 - 0.05 13.3 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 NMT1-like family TetR_N PF00440.23 AAAP01003187.1_2 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF4142 PF13628.6 AAAP01003187.1_4 - 1.9e-07 31.4 0.0 2.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) PQQ PF01011.21 AAAP01003188.1_1 - 9.2e-16 56.9 1.0 1.1e-08 34.6 0.1 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.6 AAAP01003188.1_1 - 0.00015 22.1 6.8 0.013 15.9 0.7 2.6 2 0 0 2 2 2 2 PQQ-like domain PQQ_2 PF13360.6 AAAP01003188.1_1 - 0.0012 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain SBP_bac_3 PF00497.20 AAAP01003188.1_2 - 3.8e-16 59.2 0.0 5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 FAD_binding_5 PF00941.21 AAAP01003189.1_2 - 1.3e-40 139.0 0.2 2e-40 138.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAAP01003189.1_2 - 1.9e-17 63.3 4.3 5.4e-17 61.9 4.3 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain MCPsignal PF00015.21 AAAP01003190.1_1 - 1.1e-28 100.2 45.1 1.5e-27 96.5 28.6 3.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003190.1_1 - 1.4e-05 25.3 16.2 0.026 14.8 1.4 4.2 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AAAP01003190.1_1 - 0.0044 17.0 12.6 1.3 9.0 0.6 3.9 2 2 2 4 4 4 3 Laminin Domain II DUF1664 PF07889.12 AAAP01003190.1_1 - 0.0064 16.5 3.9 7.6 6.6 0.0 3.6 2 2 2 4 4 4 3 Protein of unknown function (DUF1664) GCN5L1 PF06320.13 AAAP01003190.1_1 - 0.017 15.3 5.7 1.1 9.4 0.9 3.7 2 2 2 4 4 4 0 GCN5-like protein 1 (GCN5L1) Laminin_I PF06008.14 AAAP01003190.1_1 - 0.022 14.5 18.0 0.21 11.3 5.0 3.1 2 2 0 2 2 2 0 Laminin Domain I AAA_13 PF13166.6 AAAP01003190.1_1 - 0.21 10.2 3.1 0.26 9.9 3.1 1.4 1 0 0 1 1 1 0 AAA domain NfeD PF01957.18 AAAP01003190.1_1 - 4.2 7.8 7.9 2.1 8.8 0.7 3.3 1 1 3 4 4 4 0 NfeD-like C-terminal, partner-binding DHBP_synthase PF00926.19 AAAP01003190.1_2 - 5.2e-47 159.9 0.0 7.3e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AAAP01003190.1_2 - 8.5e-22 77.5 0.0 1.8e-21 76.4 0.0 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase II NicO PF03824.16 AAAP01003191.1_1 - 3.5e-14 52.8 6.0 4e-14 52.6 6.0 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein DsbD_2 PF13386.6 AAAP01003191.1_1 - 0.00014 21.9 11.9 0.00016 21.7 10.7 1.7 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD PF02683.15 AAAP01003191.1_1 - 0.002 18.0 4.8 0.0026 17.7 4.8 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region LapA_dom PF06305.11 AAAP01003191.1_1 - 0.012 15.4 2.9 0.012 15.4 2.9 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Na_H_Exchanger PF00999.21 AAAP01003191.1_1 - 0.024 13.5 7.1 0.019 13.7 5.2 1.6 2 0 0 2 2 2 0 Sodium/hydrogen exchanger family Phage_holin_3_6 PF07332.11 AAAP01003191.1_1 - 1.3 9.1 11.1 6.5 6.8 11.1 1.9 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 AAAP01003191.1_1 - 3 7.7 8.0 1.4 8.8 5.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) IlvN PF07991.12 AAAP01003191.1_2 - 0.018 14.6 0.1 0.15 11.7 0.1 1.9 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cuticle_3 PF11018.8 AAAP01003191.1_3 - 0.015 15.6 10.7 0.018 15.3 10.7 1.0 1 0 0 1 1 1 0 Pupal cuticle protein C1 OrsD PF12013.8 AAAP01003191.1_3 - 0.022 15.2 0.1 0.031 14.7 0.1 1.1 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D 2OG-FeII_Oxy_5 PF13759.6 AAAP01003191.1_3 - 0.028 14.8 0.3 0.035 14.5 0.3 1.1 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Amino_oxidase PF01593.24 AAAP01003192.1_1 - 4.7e-06 26.2 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase LysR_substrate PF03466.20 AAAP01003192.1_2 - 7.2e-39 133.3 2.5 7.9e-39 133.2 2.5 1.0 1 0 0 1 1 1 1 LysR substrate binding domain Cupin_2 PF07883.11 AAAP01003192.1_3 - 7e-12 44.9 1.7 7e-12 44.9 1.7 2.1 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.19 AAAP01003192.1_3 - 4.3e-06 26.7 2.3 7.7e-06 25.9 2.3 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AAAP01003192.1_3 - 0.00013 21.6 0.4 0.0076 15.9 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 AAAP01003192.1_3 - 0.00046 19.9 1.0 0.00053 19.8 1.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 AAAP01003192.1_3 - 0.0015 18.4 0.6 0.0062 16.4 0.0 2.1 1 1 1 2 2 2 1 ChrR Cupin-like domain Cupin_1 PF00190.22 AAAP01003192.1_3 - 0.0017 18.0 0.1 0.0028 17.3 0.1 1.4 1 0 0 1 1 1 1 Cupin MFS_1 PF07690.16 AAAP01003192.1_4 - 8.6e-24 84.1 23.8 1.1e-23 83.7 23.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01003192.1_4 - 0.0005 19.1 10.4 0.0005 19.1 10.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4079 PF13301.6 AAAP01003192.1_4 - 1.3 9.1 5.4 2.4 8.3 5.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Bacteriocin_IIc PF10439.9 AAAP01003193.1_1 - 4.9 7.3 11.2 6.9 6.9 11.2 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Sulfatase PF00884.23 AAAP01003193.1_3 - 6.2e-61 206.5 0.0 7.9e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AAAP01003193.1_3 - 0.025 14.2 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 AAAP01003193.1_3 - 0.066 13.9 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4253 PF14062.6 AAAP01003194.1_1 - 0.028 14.6 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) E1-N PF14463.6 AAAP01003195.1_1 - 4.8e-81 270.0 12.3 9.3e-81 269.0 12.3 1.5 1 0 0 1 1 1 1 E1 N-terminal domain ThiF PF00899.21 AAAP01003195.1_1 - 2.2e-10 40.3 0.0 4.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Prok-JAB PF14464.6 AAAP01003195.1_2 - 8.7e-15 54.5 0.3 1.1e-14 54.2 0.3 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Metal_CEHH PF14455.6 AAAP01003195.1_3 - 1.3e-07 31.4 0.1 5e-07 29.5 0.1 1.7 2 0 0 2 2 2 1 Predicted metal binding domain Peptidase_M32 PF02074.15 AAAP01003196.1_1 - 1.6e-82 277.8 0.0 1.8e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase HSP70 PF00012.20 AAAP01003196.1_2 - 2.4e-14 52.5 0.0 9.9e-08 30.6 0.1 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 AAAP01003196.1_2 - 2.7e-06 26.5 0.0 4.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 AAAP01003196.1_2 - 0.061 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 StbA protein rve PF00665.26 AAAP01003197.1_1 - 3.5e-28 98.2 0.0 4.6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01003197.1_1 - 4e-15 55.3 0.7 6.2e-15 54.7 0.7 1.3 1 0 0 1 1 1 1 Integrase core domain GFO_IDH_MocA PF01408.22 AAAP01003198.1_1 - 2.7e-24 86.3 0.3 4e-24 85.7 0.3 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAAP01003198.1_1 - 2.6e-13 50.0 0.0 4.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain YcaO PF02624.16 AAAP01003198.1_2 - 1.4e-46 159.3 0.1 2.3e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding tRNA-synt_2 PF00152.20 AAAP01003199.1_1 - 7.7e-26 90.9 0.0 9.1e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Radical_SAM PF04055.21 AAAP01003199.1_2 - 5.6e-10 39.9 0.0 1.1e-09 38.9 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01003199.1_2 - 0.00082 19.7 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003199.1_2 - 0.0031 17.6 0.0 0.0053 16.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Transket_pyr PF02779.24 AAAP01003200.1_1 - 1.5e-69 233.2 0.0 2.2e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 AAAP01003200.1_1 - 8.3e-59 199.0 0.0 1.2e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 AAAP01003200.1_1 - 5.2e-31 107.4 0.0 9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal OSCP PF00213.18 AAAP01003201.1_1 - 2.1e-43 148.4 0.2 2.3e-43 148.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyoxalase PF00903.25 AAAP01003201.1_2 - 0.019 15.2 0.0 0.081 13.1 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AAAP01003201.1_2 - 0.034 14.1 0.0 0.37 10.7 0.0 2.2 3 0 0 3 3 3 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AAAP01003201.1_2 - 0.04 14.7 0.0 0.056 14.2 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Ferrochelatase PF00762.19 AAAP01003201.1_3 - 1.2e-57 195.4 0.0 1.4e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ferrochelatase PF00762.19 AAAP01003201.1_4 - 4.6e-06 25.9 0.0 4.6e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase SKI PF01202.22 AAAP01003202.1_1 - 3.6e-06 27.2 0.0 4.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_16 PF13191.6 AAAP01003202.1_1 - 2e-05 25.0 0.0 2.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAAP01003202.1_1 - 4.1e-05 23.8 0.0 5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AAAP01003202.1_1 - 0.00026 20.8 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA_22 PF13401.6 AAAP01003202.1_1 - 0.00032 21.0 0.0 0.00036 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAAP01003202.1_1 - 0.00038 21.0 0.0 0.00041 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAAP01003202.1_1 - 0.0025 17.7 0.1 0.0066 16.4 0.1 1.5 1 1 1 2 2 2 1 NACHT domain dNK PF01712.19 AAAP01003202.1_1 - 0.0027 17.6 0.0 0.0032 17.3 0.0 1.3 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 AAAP01003202.1_1 - 0.0051 17.1 0.0 0.0062 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 AAAP01003202.1_1 - 0.0065 16.6 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain RuvB_N PF05496.12 AAAP01003202.1_1 - 0.007 16.1 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AAAP01003202.1_1 - 0.0072 16.8 0.0 0.009 16.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AAAP01003202.1_1 - 0.009 15.3 0.1 0.014 14.7 0.1 1.3 1 1 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 AAAP01003202.1_1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 AAAP01003202.1_1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 AAAP01003202.1_1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 AAAP01003202.1_1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 AAAP01003202.1_1 - 0.034 14.6 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AAAP01003202.1_1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.18 AAAP01003202.1_1 - 0.048 13.0 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 AAAP01003202.1_1 - 0.051 13.3 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AAAP01003202.1_1 - 0.058 13.1 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase Cytidylate_kin2 PF13189.6 AAAP01003202.1_1 - 0.061 13.5 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.22 AAAP01003202.1_1 - 0.063 13.7 0.0 0.088 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 AAAP01003202.1_1 - 0.064 13.0 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003202.1_1 - 0.086 13.4 0.0 0.1 13.1 0.0 1.2 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 AAAP01003202.1_1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein IPT PF01745.16 AAAP01003202.1_1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase CoaE PF01121.20 AAAP01003202.1_1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase PRK PF00485.18 AAAP01003202.1_1 - 0.13 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 AAAP01003202.1_1 - 0.17 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_3 PF07726.11 AAAP01003202.1_1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAAP01003202.1_1 - 0.21 11.5 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 AAAP01003202.1_1 - 0.21 11.0 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 AAAP01003202.1_1 - 0.24 10.9 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Herpes_Helicase PF02689.14 AAAP01003202.1_1 - 0.29 9.0 0.0 0.33 8.8 0.0 1.0 1 0 0 1 1 1 0 Helicase FCD PF07729.12 AAAP01003202.1_2 - 5.9e-25 88.1 7.0 9e-25 87.5 7.0 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01003202.1_2 - 2.3e-13 49.6 0.6 6.1e-13 48.2 0.6 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AAAP01003202.1_2 - 0.0028 18.0 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AAAP01003202.1_2 - 0.005 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAAP01003202.1_2 - 0.006 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 AAAP01003202.1_2 - 0.058 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 AAAP01003202.1_2 - 0.059 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Phosphonate-bd PF12974.7 AAAP01003202.1_2 - 0.11 12.1 0.3 0.17 11.4 0.3 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein ABC_tran PF00005.27 AAAP01003202.1_3 - 1.5e-29 103.2 0.0 2.2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AAAP01003202.1_3 - 2.4e-09 37.4 7.6 4.2e-07 30.2 0.2 4.0 2 1 1 3 3 3 2 TOBE domain AAA_21 PF13304.6 AAAP01003202.1_3 - 9.7e-05 22.3 1.8 0.089 12.6 0.3 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003202.1_3 - 0.00048 19.8 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 AAAP01003202.1_3 - 0.02 14.8 0.3 0.06 13.3 0.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 AAAP01003202.1_3 - 0.038 14.5 0.0 0.049 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Fer2_4 PF13510.6 AAAP01003202.1_3 - 0.049 13.7 0.2 11 6.2 0.0 2.8 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RsgA_GTPase PF03193.16 AAAP01003202.1_3 - 0.17 11.7 0.1 0.38 10.7 0.1 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_13 PF13166.6 AAAP01003202.1_3 - 0.19 10.3 0.0 4 6.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 AAAP01003202.1_3 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mpt_N PF09176.11 AAAP01003203.1_2 - 1.3e-33 115.0 0.5 3.1e-33 113.7 0.5 1.7 1 0 0 1 1 1 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal GHMP_kinases_N PF00288.26 AAAP01003203.1_3 - 1.3e-07 31.8 0.6 3.1e-07 30.5 0.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAAP01003203.1_3 - 0.0097 16.2 0.2 0.023 15.1 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Phenol_MetA_deg PF13557.6 AAAP01003204.1_2 - 1.7e-20 74.0 13.8 2.1e-20 73.7 13.8 1.2 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation Phage_CI_repr PF07022.13 AAAP01003205.1_3 - 0.00066 19.7 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain Epimerase PF01370.21 AAAP01003206.1_2 - 0.014 14.9 0.0 0.034 13.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003206.1_2 - 0.033 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAAP01003206.1_2 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Oxidored_FMN PF00724.20 AAAP01003207.1_1 - 1.6e-80 270.9 0.0 1.8e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.25 AAAP01003207.1_2 - 1.2e-14 54.6 0.1 1.6e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAAP01003207.1_2 - 5.6e-12 45.7 0.0 1.1e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01003207.1_2 - 8e-06 26.2 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003207.1_2 - 0.00097 19.1 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AAAP01003207.1_2 - 0.029 14.4 0.3 0.17 12.0 0.3 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01003207.1_2 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HAMP PF00672.25 AAAP01003208.1_1 - 3.9e-09 36.7 0.8 3.9e-09 36.7 0.8 3.3 3 0 0 3 3 3 1 HAMP domain CheZ PF04344.13 AAAP01003208.1_1 - 0.26 11.2 5.9 1.9 8.3 0.4 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ WXG100 PF06013.12 AAAP01003208.1_1 - 2 8.7 8.1 5.7 7.3 0.6 3.3 3 1 1 4 4 4 0 Proteins of 100 residues with WXG TruB_N PF01509.18 AAAP01003208.1_3 - 9e-52 175.4 0.0 1.2e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AAAP01003208.1_3 - 3.7e-14 52.6 0.3 7.7e-14 51.6 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AAAP01003208.1_3 - 0.00033 20.6 0.6 0.00094 19.2 0.4 2.0 2 0 0 2 2 2 1 Pseudouridine synthase II TruB, C-terminal AA_kinase PF00696.28 AAAP01003209.1_2 - 3.9e-24 85.6 0.3 4.6e-24 85.3 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family FeS_assembly_P PF01883.19 AAAP01003209.1_2 - 0.07 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein HAD_2 PF13419.6 AAAP01003209.1_3 - 4.9e-08 33.3 0.0 6.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003209.1_3 - 1.6e-06 28.6 0.0 0.003 17.9 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003209.1_3 - 0.0017 18.8 0.3 0.0029 18.0 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003209.1_3 - 0.022 14.8 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Zincin_1 PF06262.11 AAAP01003209.1_4 - 1.4e-33 114.8 0.1 2e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_M10 PF00413.24 AAAP01003209.1_4 - 0.016 15.1 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 AAAP01003209.1_4 - 0.028 13.6 0.7 0.038 13.2 0.7 1.1 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 AAAP01003209.1_4 - 0.25 10.9 1.2 0.35 10.4 1.2 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase SelR PF01641.18 AAAP01003210.1_1 - 1.3e-05 25.2 0.0 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 SelR domain S1 PF00575.23 AAAP01003210.1_2 - 4e-17 62.3 5.2 1.2e-16 60.8 3.4 2.5 3 0 0 3 3 3 1 S1 RNA binding domain RNase_PH PF01138.21 AAAP01003210.1_2 - 7.1e-16 58.9 0.0 1.4e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 KH_1 PF00013.29 AAAP01003210.1_2 - 7.8e-13 48.0 1.8 3.6e-12 45.9 2.0 2.1 2 0 0 2 2 2 1 KH domain RNase_PH_C PF03725.15 AAAP01003210.1_2 - 5.5e-06 26.3 0.5 1e-05 25.4 0.5 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_2 PF07650.17 AAAP01003210.1_2 - 0.014 15.2 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 KH domain IalB PF06776.12 AAAP01003211.1_2 - 2e-37 128.2 0.0 2.5e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Invasion associated locus B (IalB) protein BacA PF02673.18 AAAP01003212.1_2 - 1.2e-75 254.6 10.1 1.4e-75 254.4 10.1 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA CBP_BcsG PF11658.8 AAAP01003212.1_2 - 0.15 10.4 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG GST_N_3 PF13417.6 AAAP01003212.1_3 - 2.4e-13 50.3 0.0 4.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003212.1_3 - 5e-09 36.3 0.0 1.7e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01003212.1_3 - 9.7e-07 29.1 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AAAP01003212.1_3 - 2.1e-06 27.8 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAAP01003212.1_3 - 5.4e-05 23.3 0.1 0.00013 22.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAAP01003212.1_3 - 0.014 15.4 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 AAAP01003212.1_3 - 0.21 11.8 0.0 0.64 10.3 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin ATPase PF06745.13 AAAP01003213.1_1 - 2.1e-28 99.3 0.1 4.2e-28 98.3 0.0 1.5 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 AAAP01003213.1_1 - 7.7e-09 35.4 0.8 3.2e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003213.1_1 - 3.4e-05 24.3 1.4 0.00034 21.0 1.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 AAAP01003213.1_1 - 0.00021 21.2 0.0 0.00047 20.1 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 AAAP01003213.1_1 - 0.00022 21.5 1.2 0.00056 20.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01003213.1_1 - 0.00089 19.7 0.1 0.0023 18.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 AAAP01003213.1_1 - 0.0018 17.2 1.1 0.0019 17.2 0.0 1.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain APG6_N PF17675.1 AAAP01003213.1_1 - 0.0031 18.0 3.6 0.0047 17.5 3.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Sigma54_activat PF00158.26 AAAP01003213.1_1 - 0.0034 17.1 0.1 0.0097 15.6 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 AAAP01003213.1_1 - 0.004 16.5 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 AAAP01003213.1_1 - 0.0042 16.9 0.7 0.013 15.2 0.1 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 AAAP01003213.1_1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAAP01003213.1_1 - 0.041 13.6 0.0 0.082 12.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain Pyridox_ox_2 PF12900.7 AAAP01003213.1_1 - 0.055 13.5 0.4 0.098 12.6 0.4 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase AAA_7 PF12775.7 AAAP01003213.1_1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 AAAP01003213.1_1 - 0.077 12.8 0.1 9.7 5.9 0.3 2.2 2 0 0 2 2 2 0 AAA domain MEDS PF14417.6 AAAP01003213.1_1 - 0.081 12.8 0.8 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_23 PF13476.6 AAAP01003213.1_1 - 0.091 13.3 1.4 5.5 7.4 0.3 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 AAAP01003213.1_1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 AAAP01003213.1_1 - 0.16 11.8 0.4 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PAN_4 PF14295.6 AAAP01003213.1_1 - 0.16 11.9 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 PAN domain KASH_CCD PF14662.6 AAAP01003213.1_1 - 0.29 11.0 8.7 0.45 10.3 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 AAAP01003213.1_1 - 0.3 10.6 4.4 0.44 10.1 4.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KaiB PF07689.12 AAAP01003213.1_2 - 9e-24 83.0 0.0 1e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 KaiB domain KaiB PF07689.12 AAAP01003213.1_3 - 2.2e-19 69.0 0.0 2.6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 KaiB domain PAS_4 PF08448.10 AAAP01003213.1_4 - 2e-14 53.8 0.2 4.4e-14 52.7 0.2 1.6 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003213.1_4 - 3e-10 40.0 0.1 3e-10 40.0 0.1 2.6 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003213.1_4 - 1e-07 32.2 0.0 3.4e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003213.1_4 - 1.4e-06 28.3 0.0 3.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003213.1_4 - 0.0016 18.4 0.1 0.0096 15.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain Rootletin PF15035.6 AAAP01003213.1_4 - 0.0074 16.3 0.5 0.0074 16.3 0.5 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion PKcGMP_CC PF16808.5 AAAP01003213.1_4 - 0.066 13.1 1.3 0.19 11.6 1.3 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Nkap_C PF06047.11 AAAP01003213.1_4 - 0.075 13.2 0.0 0.075 13.2 0.0 2.9 3 1 0 3 3 3 0 NF-kappa-B-activating protein C-terminal domain DUF4140 PF13600.6 AAAP01003213.1_4 - 1.3 9.5 5.3 7.2 7.1 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1949 PF09186.11 AAAP01003214.1_2 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) RNase_H PF00075.24 AAAP01003214.1_3 - 1.4e-38 132.3 0.0 1.8e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 AAAP01003214.1_3 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RHH_1 PF01402.21 AAAP01003214.1_3 - 0.066 13.2 3.0 0.96 9.5 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Pur_DNA_glyco PF02245.16 AAAP01003214.1_4 - 4.2e-10 39.4 0.0 4.4e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Flg_hook PF02120.16 AAAP01003215.1_1 - 1.3e-15 57.0 0.1 1.3e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK FlgD PF03963.14 AAAP01003215.1_2 - 2.9e-20 72.3 9.3 6.8e-20 71.2 9.3 1.6 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AAAP01003215.1_2 - 1.2e-15 57.1 3.7 3.5e-15 55.6 3.7 1.7 1 0 0 1 1 1 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AAAP01003215.1_2 - 9.6e-12 45.0 3.6 2e-11 44.0 3.6 1.6 1 0 0 1 1 1 1 FlgD Tudor-like domain DUF2271 PF10029.9 AAAP01003215.1_2 - 0.0025 17.4 0.3 0.0049 16.5 0.3 1.6 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) DUF4165 PF13752.6 AAAP01003215.1_2 - 0.0036 17.3 0.6 0.012 15.6 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4165) MetallophosN PF16371.5 AAAP01003215.1_2 - 0.23 11.8 1.5 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase DUF1153 PF06627.11 AAAP01003215.1_3 - 9.8e-42 141.0 0.0 1.1e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1153) DUF3565 PF12088.8 AAAP01003215.1_3 - 0.093 12.7 0.5 3.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) PAS_3 PF08447.12 AAAP01003216.1_1 - 3.9e-33 113.6 0.3 7.9e-18 64.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold MCPsignal PF00015.21 AAAP01003216.1_1 - 4.4e-29 101.5 40.5 8.9e-29 100.5 27.8 2.3 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_4 PF08448.10 AAAP01003216.1_1 - 1.4e-24 86.4 0.1 1.8e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003216.1_1 - 3.6e-24 85.0 0.0 2.9e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003216.1_1 - 2.8e-15 56.3 0.0 9.5e-08 32.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01003216.1_1 - 6.8e-07 29.2 0.1 0.016 15.2 0.0 2.9 3 0 0 3 3 3 2 PAS domain Baculo_PEP_C PF04513.12 AAAP01003216.1_1 - 0.066 13.3 17.7 0.57 10.2 4.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad1 PF08649.10 AAAP01003216.1_1 - 0.091 13.0 0.6 0.59 10.4 0.2 2.7 2 0 0 2 2 1 0 DASH complex subunit Dad1 Ferritin PF00210.24 AAAP01003216.1_1 - 0.094 12.6 0.6 26 4.7 0.0 3.0 4 0 0 4 4 3 0 Ferritin-like domain CENP-H PF05837.12 AAAP01003216.1_1 - 0.23 11.9 9.7 2.3 8.7 5.2 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) zf-C4H2 PF10146.9 AAAP01003216.1_1 - 0.26 11.6 1.3 6 7.1 0.3 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Med10 PF09748.9 AAAP01003216.1_1 - 0.44 10.5 2.2 18 5.3 0.5 2.6 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex SesA PF17107.5 AAAP01003216.1_1 - 0.45 10.7 10.3 0.17 12.1 0.7 3.1 1 1 2 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec34 PF04136.15 AAAP01003216.1_1 - 0.79 9.6 5.4 4.1 7.3 0.1 2.5 2 1 0 2 2 2 0 Sec34-like family APG17 PF04108.12 AAAP01003216.1_1 - 0.89 8.6 7.0 15 4.5 7.0 2.2 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF1664 PF07889.12 AAAP01003216.1_1 - 1.1 9.4 9.6 3 7.9 3.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ECH_2 PF16113.5 AAAP01003216.1_1 - 1.2 8.6 10.1 5.4 6.4 9.6 2.0 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase T3SSipB PF16535.5 AAAP01003216.1_1 - 1.6 9.2 19.4 2.3 8.7 3.0 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB Fib_alpha PF08702.10 AAAP01003216.1_1 - 2 8.6 4.2 16 5.7 1.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 AAAP01003216.1_1 - 3.3 8.0 18.7 4.1 7.7 2.0 4.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 AAAP01003216.1_1 - 4.4 7.4 8.9 13 5.9 2.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 AAAP01003216.1_1 - 5 7.4 6.0 21 5.4 1.0 3.0 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 AAAP01003216.1_1 - 7.9 5.7 12.8 2.5 7.3 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Acyl_transf_3 PF01757.22 AAAP01003217.1_1 - 1.1e-10 41.2 24.8 1.1e-10 41.2 24.8 2.3 1 1 0 2 2 2 1 Acyltransferase family DNA_pol3_delta2 PF13177.6 AAAP01003217.1_2 - 9.2e-23 80.8 0.0 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit GAF PF01590.26 AAAP01003218.1_1 - 1.2e-09 38.9 0.0 2.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain HemolysinCabind PF00353.19 AAAP01003219.1_1 - 1.4e-09 37.7 26.4 5.1e-08 32.7 10.6 2.1 2 0 0 2 2 2 2 RTX calcium-binding nonapeptide repeat (4 copies) HemolysinCabind PF00353.19 AAAP01003219.1_2 - 5.4e-44 147.7 214.4 2.3e-06 27.4 10.5 16.2 10 7 5 15 15 15 11 RTX calcium-binding nonapeptide repeat (4 copies) MraZ PF02381.18 AAAP01003219.1_2 - 0.13 12.2 0.0 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 MraZ protein, putative antitoxin-like KH_6 PF15985.5 AAAP01003219.1_2 - 0.68 10.3 5.1 1.5e+02 2.8 0.0 5.7 8 0 0 8 8 8 0 KH domain Peptidase_M15_3 PF08291.11 AAAP01003219.1_2 - 3.5 7.7 14.0 28 4.9 0.0 5.2 5 2 1 6 6 6 0 Peptidase M15 Peptidase_C107 PF17222.3 AAAP01003219.1_2 - 6.6 5.6 9.5 28 3.5 0.3 3.9 4 0 0 4 4 4 0 Viral cysteine endopeptidase C107 ABC_tran PF00005.27 AAAP01003220.1_1 - 8.3e-26 91.1 0.0 9.4e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003220.1_1 - 1.7e-05 24.8 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003220.1_1 - 0.00098 19.7 0.0 0.0013 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003220.1_1 - 0.0036 17.7 2.1 0.0048 17.3 2.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003220.1_1 - 0.0053 16.5 0.9 0.0095 15.7 0.9 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003220.1_1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AAAP01003220.1_1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAAP01003220.1_1 - 0.019 15.1 0.1 0.042 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003220.1_1 - 0.02 14.5 0.8 0.092 12.3 0.8 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003220.1_1 - 0.024 14.5 0.1 0.035 14.0 0.1 1.4 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 AAAP01003220.1_1 - 0.029 14.8 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAAP01003220.1_1 - 0.045 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 AAAP01003220.1_1 - 0.05 13.3 0.0 0.065 12.9 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 AAAP01003220.1_1 - 0.067 12.8 0.1 0.091 12.3 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 AAAP01003220.1_1 - 0.069 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 AAAP01003220.1_1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003220.1_1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01003220.1_1 - 0.074 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TsaE PF02367.17 AAAP01003220.1_1 - 0.078 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AAAP01003220.1_1 - 0.087 13.1 0.3 0.19 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003220.1_1 - 0.11 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01003220.1_1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain DUF3584 PF12128.8 AAAP01003220.1_1 - 0.14 9.6 0.4 0.19 9.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.12 AAAP01003220.1_1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 AAAP01003220.1_1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RecA PF00154.21 AAAP01003220.1_1 - 0.22 10.9 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_13 PF13166.6 AAAP01003220.1_1 - 0.34 9.5 0.0 0.44 9.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain FecCD PF01032.18 AAAP01003220.1_2 - 1.3e-75 254.3 41.3 1.6e-75 254.0 41.3 1.0 1 0 0 1 1 1 1 FecCD transport family Peripla_BP_2 PF01497.18 AAAP01003220.1_3 - 2.1e-08 34.0 0.0 2.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein HTH_3 PF01381.22 AAAP01003221.1_1 - 1.1e-12 47.8 0.4 2.5e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003221.1_1 - 9.5e-09 35.5 0.1 2e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003221.1_1 - 3.8e-06 26.8 0.0 6.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003221.1_1 - 0.045 14.2 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Ribophorin_II PF05817.14 AAAP01003221.1_1 - 0.14 10.7 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Pou PF00157.17 AAAP01003221.1_1 - 0.18 11.8 0.2 0.39 10.7 0.2 1.5 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_17 PF12728.7 AAAP01003221.1_2 - 9.3e-15 54.6 0.3 1.2e-14 54.3 0.3 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain ANT PF03374.14 AAAP01003221.1_2 - 0.00077 19.8 0.0 0.0008 19.7 0.0 1.0 1 0 0 1 1 1 1 Phage antirepressor protein KilAC domain PBP_like PF12727.7 AAAP01003221.1_3 - 2.6e-53 180.0 0.0 3.2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAAP01003221.1_3 - 0.017 14.9 0.3 0.018 14.8 0.3 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF2478 PF10649.9 AAAP01003221.1_4 - 4.8e-21 75.0 0.0 5.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) NTPase_1 PF03266.15 AAAP01003221.1_4 - 0.058 13.3 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 NTPase CcmE PF03100.15 AAAP01003222.1_1 - 7.8e-45 152.0 0.0 9.6e-45 151.7 0.0 1.1 1 0 0 1 1 1 1 CcmE TPR_19 PF14559.6 AAAP01003222.1_2 - 0.00059 20.3 18.7 0.019 15.5 0.5 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003222.1_2 - 0.0008 20.0 35.3 0.11 13.4 1.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003222.1_2 - 0.012 15.7 8.0 5.8 7.3 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AAAP01003222.1_2 - 0.016 15.1 3.4 0.36 10.7 0.2 2.3 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 AAAP01003222.1_2 - 0.018 15.2 1.0 0.018 15.2 1.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat OHCU_decarbox PF09349.10 AAAP01003222.1_2 - 0.065 13.7 2.7 0.76 10.3 0.2 2.3 2 0 0 2 2 2 0 OHCU decarboxylase Vps5 PF09325.10 AAAP01003222.1_2 - 0.07 12.7 0.1 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 Vps5 C terminal like TPR_20 PF14561.6 AAAP01003222.1_2 - 0.48 10.8 0.1 0.48 10.8 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003222.1_2 - 3.4 8.5 13.9 13 6.7 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_27 PF13463.6 AAAP01003223.1_1 - 0.064 13.8 0.0 0.093 13.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Nuc_deoxyrib_tr PF05014.15 AAAP01003223.1_7 - 0.00017 21.6 0.0 0.00018 21.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DFP PF04127.15 AAAP01003224.1_3 - 5.8e-69 231.7 0.0 1e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AAAP01003224.1_3 - 1.6e-39 135.2 0.2 2.2e-39 134.7 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein DUF2399 PF09664.10 AAAP01003224.1_3 - 0.0066 16.4 0.1 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) Mobilization_B PF17511.2 AAAP01003224.1_3 - 0.015 15.6 0.5 0.031 14.6 0.5 1.5 1 0 0 1 1 1 0 Mobilization protein B Mur_ligase PF01225.25 AAAP01003224.1_3 - 0.031 14.6 0.2 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Mur ligase family, catalytic domain YjeF_N PF03853.15 AAAP01003224.1_3 - 0.12 12.3 1.6 0.84 9.5 0.0 2.5 2 1 1 3 3 3 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 AAAP01003225.1_1 - 1.1e-18 67.6 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAAP01003225.1_1 - 1e-07 32.3 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 AAAP01003225.1_1 - 2e-05 24.4 0.1 4.4e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 AAAP01003225.1_1 - 0.0028 17.0 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAAP01003225.1_1 - 0.0049 16.8 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAAP01003225.1_1 - 0.031 14.3 0.1 2.2 8.3 0.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 AAAP01003225.1_1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AAAP01003225.1_1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 AAAP01003225.1_2 - 1.9e-33 116.0 0.0 7.8e-32 110.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SLT PF01464.20 AAAP01003226.1_1 - 7.2e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Phage_lysozyme2 PF18013.1 AAAP01003226.1_1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail lysozyme DUF2336 PF10098.9 AAAP01003226.1_2 - 1.4e-48 165.7 30.7 1.4e-48 165.7 30.7 1.6 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2336) HEAT_2 PF13646.6 AAAP01003226.1_2 - 0.0016 18.8 1.9 0.0016 18.8 1.9 3.6 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 AAAP01003226.1_2 - 0.0086 16.2 5.4 0.11 12.8 0.3 4.2 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 AAAP01003226.1_2 - 0.42 10.7 3.8 8.8 6.5 0.0 3.9 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat Phosphonate-bd PF12974.7 AAAP01003227.1_1 - 1.7e-38 132.6 0.0 2.1e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAAP01003227.1_1 - 0.0017 18.4 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Response_reg PF00072.24 AAAP01003227.1_2 - 3e-19 69.3 0.0 2.3e-18 66.4 0.0 2.2 2 1 1 3 3 3 1 Response regulator receiver domain HD_5 PF13487.6 AAAP01003227.1_2 - 0.00062 20.0 0.1 0.0018 18.5 0.1 1.7 1 0 0 1 1 1 1 HD domain Hpt PF01627.23 AAAP01003228.1_1 - 2e-17 63.2 0.6 8.3e-17 61.2 0.1 2.3 2 0 0 2 2 2 1 Hpt domain H-kinase_dim PF02895.14 AAAP01003228.1_1 - 8.4e-14 51.7 0.5 8.1e-13 48.6 1.1 2.5 3 0 0 3 3 3 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.26 AAAP01003228.1_1 - 2.6e-10 40.8 0.3 7.2e-10 39.4 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003228.1_1 - 0.0073 16.3 0.2 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003228.1_1 - 0.02 14.7 0.3 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3275 PF11679.8 AAAP01003228.1_1 - 1.4 8.9 5.2 15 5.5 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3275) HPTransfase PF10090.9 AAAP01003228.1_2 - 1e-36 125.5 0.0 1.6e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain HisKA PF00512.25 AAAP01003228.1_2 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF373 PF04123.13 AAAP01003229.1_1 - 1.3 8.3 6.5 0.091 12.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Aminotran_1_2 PF00155.21 AAAP01003229.1_2 - 4e-27 95.3 0.0 5e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01003229.1_2 - 5.2e-07 28.5 0.0 7.5e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AAAP01003229.1_2 - 4.4e-05 22.9 0.1 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SHMT PF00464.19 AAAP01003229.1_2 - 0.11 11.1 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Glyco_trans_1_4 PF13692.6 AAAP01003230.1_1 - 3.6e-26 92.2 0.2 5.4e-26 91.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003230.1_1 - 4.2e-26 91.5 0.0 7.6e-26 90.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003230.1_1 - 1.1e-13 51.4 0.0 2.5e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003230.1_1 - 0.0063 17.0 0.3 0.0063 17.0 0.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Thioesterase PF00975.20 AAAP01003230.1_3 - 1.5e-15 58.0 0.1 2.3e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 AAAP01003230.1_3 - 9.2e-13 48.3 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site PepSY_2 PF13670.6 AAAP01003231.1_1 - 1.4e-19 69.9 0.1 1.5e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DNA_pol3_delta2 PF13177.6 AAAP01003231.1_3 - 8.7e-08 32.1 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 AAAP01003231.1_3 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AAAP01003231.1_3 - 0.00086 19.9 0.0 0.0014 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003231.1_3 - 0.00086 19.7 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 AAAP01003231.1_3 - 0.0068 16.4 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AAAP01003231.1_3 - 0.0089 16.5 0.2 0.016 15.7 0.2 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AAAP01003231.1_3 - 0.015 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AAAP01003231.1_3 - 0.016 15.5 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003231.1_3 - 0.022 14.9 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01003231.1_3 - 0.022 14.7 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 AAAP01003231.1_3 - 0.032 14.3 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain HTH_Tnp_IS1 PF12759.7 AAAP01003231.1_3 - 0.12 12.0 1.5 0.24 11.0 1.0 1.8 2 0 0 2 2 2 0 InsA C-terminal domain DUF815 PF05673.13 AAAP01003231.1_3 - 0.2 10.8 0.0 0.58 9.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC2_membrane PF01061.24 AAAP01003232.1_1 - 4.1e-14 52.5 1.9 4.6e-14 52.3 1.9 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01003232.1_1 - 0.041 13.0 0.1 0.041 13.0 0.1 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAAP01003232.1_1 - 0.069 12.4 9.6 0.11 11.7 1.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAAP01003232.1_2 - 4.6e-28 98.4 0.0 6.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003232.1_2 - 1.5e-11 44.7 0.3 1.7e-07 31.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AAAP01003232.1_2 - 0.00011 22.8 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 AAAP01003232.1_2 - 0.0023 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 AAAP01003232.1_2 - 0.0024 17.5 0.8 0.0031 17.2 0.1 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 AAAP01003232.1_2 - 0.0059 17.1 0.0 0.0073 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003232.1_2 - 0.0061 17.0 2.0 0.013 15.8 2.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain KdpD PF02702.17 AAAP01003232.1_2 - 0.021 14.3 0.0 0.062 12.8 0.0 1.7 1 1 1 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_30 PF13604.6 AAAP01003232.1_2 - 0.022 14.5 0.1 0.022 14.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAAP01003232.1_2 - 0.038 14.2 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003232.1_2 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAAP01003232.1_2 - 0.099 12.4 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 AAAP01003232.1_2 - 0.16 12.4 0.0 0.39 11.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAAP01003232.1_2 - 0.23 11.3 0.0 0.37 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2298 PF10060.9 AAAP01003232.1_3 - 0.0087 14.8 1.0 0.009 14.8 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) Collectrin PF16959.5 AAAP01003232.1_3 - 0.029 14.1 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Renal amino acid transporter DUF3040 PF11239.8 AAAP01003232.1_3 - 3.2 8.1 7.4 4.3 7.7 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Glycos_transf_1 PF00534.20 AAAP01003233.1_1 - 2.2e-21 76.2 0.0 2.9e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003233.1_1 - 6.8e-17 62.2 0.0 1.1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003233.1_1 - 2e-05 24.7 0.2 6.1e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01003233.1_1 - 0.00078 19.8 0.0 0.0035 17.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AAAP01003233.1_2 - 6.9e-10 39.0 0.0 2.5e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003233.1_2 - 9.3e-08 32.2 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003233.1_2 - 0.0091 16.5 0.0 0.035 14.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 NMT1_2 PF13379.6 AAAP01003234.1_1 - 4.5e-30 105.2 3.8 6.1e-30 104.7 3.8 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01003234.1_1 - 9.9e-15 55.1 0.3 1.1e-13 51.6 0.3 2.0 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AAAP01003234.1_1 - 0.00021 20.8 0.0 0.0025 17.3 0.1 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AAAP01003234.1_1 - 0.0075 15.9 0.5 0.035 13.7 0.4 2.2 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.7 AAAP01003234.1_1 - 0.012 15.2 1.0 0.045 13.3 0.9 1.9 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3597 PF12200.8 AAAP01003234.1_2 - 5.9e-51 172.3 0.2 6.7e-51 172.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) BetaGal_dom3 PF13363.6 AAAP01003234.1_2 - 0.055 13.0 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 HTH_17 PF12728.7 AAAP01003235.1_1 - 9.4e-09 35.3 0.1 1.2e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 AAAP01003235.1_1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Phage_AlpA PF05930.12 AAAP01003235.1_1 - 0.028 14.2 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) MerR PF00376.23 AAAP01003235.1_1 - 0.031 14.0 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 MerR family regulatory protein RPA PF10134.9 AAAP01003235.1_2 - 1.2e-92 309.6 0.0 1.3e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Replication initiator protein A Rep_3 PF01051.21 AAAP01003235.1_2 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Initiator Replication protein AAA_31 PF13614.6 AAAP01003235.1_3 - 2e-21 76.7 0.0 7e-12 45.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 AAAP01003235.1_3 - 5.9e-15 55.4 0.0 1.1e-14 54.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAAP01003235.1_3 - 6.1e-11 42.1 0.0 9.4e-06 25.1 0.0 2.4 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 AAAP01003235.1_3 - 2.9e-07 30.2 0.0 8.4e-07 28.7 0.0 1.8 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AAAP01003235.1_3 - 8.3e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAAP01003235.1_3 - 0.00016 21.2 0.1 0.028 13.9 0.1 2.3 1 1 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 AAAP01003235.1_3 - 0.00021 20.9 2.0 0.00033 20.3 0.4 2.1 2 1 0 2 2 2 1 AAA domain VirC1 PF07015.11 AAAP01003235.1_3 - 0.00026 20.4 0.1 0.00089 18.6 0.1 1.8 1 1 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 AAAP01003235.1_3 - 0.0007 19.4 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Glyco_trans_4_4 PF13579.6 AAAP01003235.1_3 - 0.0046 17.4 9.4 0.022 15.2 9.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01003235.1_3 - 0.025 14.6 0.4 0.065 13.2 0.4 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 NACHT PF05729.12 AAAP01003235.1_3 - 0.045 13.7 0.7 0.089 12.7 0.2 1.9 2 1 0 2 2 2 0 NACHT domain MobB PF03205.14 AAAP01003235.1_3 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 AAAP01003235.1_3 - 0.098 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ParD PF09386.10 AAAP01003235.1_4 - 0.0082 16.5 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Antitoxin ParD DUF2840 PF11000.8 AAAP01003235.1_5 - 9.3e-50 168.3 0.4 1.1e-49 168.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2840) ParD_like PF11903.8 AAAP01003235.1_5 - 0.056 13.5 0.2 0.11 12.6 0.1 1.7 2 1 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system DUF305 PF03713.13 AAAP01003236.1_1 - 2.9e-10 40.5 15.3 3.8e-10 40.1 15.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF2946 PF11162.8 AAAP01003236.1_1 - 0.0005 20.7 3.5 0.00064 20.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) DUF4142 PF13628.6 AAAP01003236.1_1 - 0.0032 17.7 2.5 0.0032 17.7 2.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4142) CcdA PF07362.12 AAAP01003236.1_1 - 0.48 10.9 3.5 0.63 10.5 1.4 2.0 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF5018 PF16410.5 AAAP01003236.1_4 - 0.39 9.4 2.7 0.46 9.1 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) PhoH PF02562.16 AAAP01003237.1_2 - 1.8e-87 292.1 0.0 2.4e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AAAP01003237.1_2 - 1.3e-09 38.1 0.1 2.5e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAAP01003237.1_2 - 9e-06 26.1 0.1 4.5e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 AAAP01003237.1_2 - 1.3e-05 24.9 0.1 0.0061 16.1 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 AAAP01003237.1_2 - 6e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 AAAP01003237.1_2 - 0.00037 20.1 0.1 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAAP01003237.1_2 - 0.0046 17.2 0.0 0.016 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AAAP01003237.1_2 - 0.038 13.8 0.0 4 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 AAAP01003237.1_2 - 0.07 12.9 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.23 AAAP01003237.1_2 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.9 AAAP01003237.1_2 - 0.21 10.8 0.0 1.2 8.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Radical_SAM PF04055.21 AAAP01003237.1_3 - 3e-27 96.0 0.0 4.2e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 AAAP01003237.1_3 - 2.3e-10 40.3 0.1 6.6e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 TRAM domain Cytochrome_C7 PF14522.6 AAAP01003238.1_2 - 0.068 13.2 0.8 0.29 11.2 0.8 1.9 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_C PF00034.21 AAAP01003238.1_2 - 0.4 11.9 6.5 6.7 7.9 1.2 2.5 1 1 1 2 2 2 0 Cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003238.1_2 - 0.79 9.5 4.8 10 5.9 0.9 2.3 1 1 1 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_CBB3 PF13442.6 AAAP01003238.1_2 - 3.7 7.9 9.9 1.6 9.1 2.4 2.6 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Fer2_2 PF01799.20 AAAP01003238.1_3 - 0.00024 21.0 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 [2Fe-2S] binding domain PrmA PF06325.13 AAAP01003239.1_1 - 4.1e-11 42.8 0.5 4.9e-11 42.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 AAAP01003239.1_1 - 1.5e-07 31.3 0.0 3.2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 AAAP01003239.1_1 - 5.6e-07 29.3 0.1 7.3e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 AAAP01003239.1_1 - 6.2e-06 26.1 0.0 7.4e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 AAAP01003239.1_1 - 0.00033 21.3 0.3 0.0013 19.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAAP01003239.1_1 - 0.0016 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 AAAP01003239.1_1 - 0.016 14.8 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 AAAP01003239.1_1 - 0.029 13.5 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF1772 PF08592.11 AAAP01003239.1_2 - 0.022 15.1 0.3 0.028 14.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) p12I PF12233.8 AAAP01003239.1_2 - 0.03 14.8 3.4 0.038 14.5 3.4 1.1 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein PGPGW PF09656.10 AAAP01003239.1_2 - 0.97 9.0 8.6 0.066 12.7 3.4 1.8 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Radical_SAM PF04055.21 AAAP01003240.1_1 - 0.0017 18.8 0.0 0.047 14.1 0.0 2.2 2 0 0 2 2 2 2 Radical SAM superfamily SHOCT PF09851.9 AAAP01003240.1_2 - 1.5e-07 30.9 0.5 2.6e-07 30.2 0.5 1.4 1 0 0 1 1 1 1 Short C-terminal domain SbcCD_C PF13558.6 AAAP01003241.1_1 - 3.8e-12 46.3 0.5 7.6e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AAAP01003241.1_1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 AAAP01003241.1_1 - 0.19 11.0 1.2 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Suppressor_APC PF11414.8 AAAP01003241.1_2 - 0.034 14.2 0.2 3.7 7.7 0.0 3.2 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein Spc7 PF08317.11 AAAP01003241.1_2 - 1.3 7.9 3.8 1.1 8.1 0.4 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF465 PF04325.13 AAAP01003241.1_2 - 2.1 8.5 5.2 1.5 8.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF465) TPP_enzyme_N PF02776.18 AAAP01003242.1_1 - 1.5e-57 194.0 0.1 3.7e-57 192.7 0.1 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAAP01003242.1_1 - 2.6e-52 176.7 0.0 3.5e-51 173.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAAP01003242.1_1 - 2.5e-43 147.1 0.0 4.3e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain PseudoU_synth_2 PF00849.22 AAAP01003243.1_2 - 1.5e-18 67.4 0.0 1.4e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase SpoU_sub_bind PF08032.12 AAAP01003243.1_3 - 1.2e-07 31.8 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SpoU_methylase PF00588.19 AAAP01003243.1_3 - 2.8e-07 30.8 0.0 5.2e-07 29.9 0.0 1.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family Glycos_transf_2 PF00535.26 AAAP01003244.1_1 - 4.9e-16 59.0 0.0 8.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003244.1_1 - 4.2e-05 23.6 0.0 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003244.1_1 - 0.19 12.3 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003244.1_2 - 2.8e-10 40.5 0.1 3.4e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003244.1_2 - 2e-05 24.6 0.2 2.6e-05 24.2 0.2 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AAAP01003244.1_2 - 3.4e-05 23.7 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.6 AAAP01003244.1_2 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family Glyco_transf_7C PF02709.14 AAAP01003244.1_2 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 AAAP01003244.1_2 - 0.02 14.4 0.3 0.036 13.5 0.3 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AAAP01003244.1_2 - 0.022 14.2 0.0 0.04 13.4 0.0 1.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 HTH_38 PF13936.6 AAAP01003245.1_1 - 0.00021 21.0 0.2 0.00043 20.0 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain WES_acyltransf PF03007.16 AAAP01003245.1_1 - 0.0099 15.7 0.4 0.011 15.5 0.4 1.0 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain HTH_23 PF13384.6 AAAP01003245.1_1 - 0.083 12.7 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 AAAP01003245.1_3 - 0.06 13.4 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix RusA PF05866.11 AAAP01003245.1_4 - 0.0013 19.3 0.0 0.0021 18.6 0.0 1.5 1 1 0 1 1 1 1 Endodeoxyribonuclease RusA Tim29 PF10171.9 AAAP01003245.1_4 - 0.23 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Patatin PF01734.22 AAAP01003246.1_1 - 4.5e-21 76.0 0.4 9e-21 75.0 0.4 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_6 PF12697.7 AAAP01003246.1_1 - 0.00022 21.9 0.5 0.00049 20.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2235 PF09994.9 AAAP01003246.1_2 - 2e-46 158.6 0.0 2.5e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_1 PF00561.20 AAAP01003246.1_2 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pterin_4a PF01329.19 AAAP01003247.1_1 - 5.8e-26 90.5 1.4 7.4e-26 90.2 1.4 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase SBP_bac_3 PF00497.20 AAAP01003247.1_2 - 9.6e-07 28.5 0.0 3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAAP01003247.1_2 - 2.4e-06 27.7 0.0 2.2e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAAP01003247.1_2 - 0.00074 19.3 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 NMT1-like family Glyco_trans_1_4 PF13692.6 AAAP01003248.1_1 - 3.2e-18 66.4 0.2 5.9e-18 65.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003248.1_1 - 6.8e-18 64.8 0.0 1.9e-17 63.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003248.1_1 - 9.5e-06 25.7 0.9 3.2e-05 24.0 0.8 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 RNase_HII PF01351.18 AAAP01003248.1_2 - 9e-33 113.8 0.0 1.1e-32 113.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Radical_SAM PF04055.21 AAAP01003248.1_3 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF167 PF02594.16 AAAP01003249.1_1 - 1.8e-23 82.4 0.1 2.2e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 YqgF PF14639.6 AAAP01003249.1_1 - 0.18 11.6 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Cytidylate_kin PF02224.18 AAAP01003249.1_2 - 8.8e-51 172.6 2.9 2.9e-50 170.9 2.9 1.7 1 1 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 AAAP01003249.1_2 - 3.6e-06 27.5 0.2 1.2e-05 25.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AAAP01003249.1_2 - 2.4e-05 24.5 0.2 3.3e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 Cytidylate kinase-like family ADK PF00406.22 AAAP01003249.1_2 - 0.00023 21.3 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.6 AAAP01003249.1_2 - 0.0024 18.1 4.5 0.15 12.2 0.0 3.6 2 2 3 5 5 5 1 AAA domain AAA_18 PF13238.6 AAAP01003249.1_2 - 0.016 15.7 0.0 0.066 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 AAAP01003249.1_2 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase EPSP_synthase PF00275.20 AAAP01003249.1_3 - 3.9e-90 302.5 0.1 4.4e-90 302.4 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Glyoxalase_6 PF18029.1 AAAP01003249.1_3 - 0.14 12.9 7.0 0.15 12.9 0.5 3.6 4 0 0 4 4 4 0 Glyoxalase-like domain Virul_fac_BrkB PF03631.15 AAAP01003250.1_1 - 1.2e-06 28.4 0.3 1.3e-06 28.2 0.3 1.1 1 0 0 1 1 1 1 Virulence factor BrkB PAS_3 PF08447.12 AAAP01003250.1_2 - 9.9e-45 150.8 0.3 1.1e-21 77.0 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01003250.1_2 - 1.1e-15 57.8 4.7 2.7e-07 30.8 1.1 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003250.1_2 - 7.2e-14 51.9 0.0 6.1e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003250.1_2 - 7.7e-14 51.7 0.0 2.3e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 AAAP01003250.1_2 - 0.022 14.9 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_10 PF13596.6 AAAP01003250.1_2 - 0.1 13.2 0.0 8.8 7.0 0.0 2.4 2 1 0 2 2 2 0 PAS domain AAA_29 PF13555.6 AAAP01003251.1_1 - 2.2e-13 49.7 0.1 4.2e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003251.1_1 - 3.1e-06 27.8 0.0 7.7e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003251.1_1 - 0.0093 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AAAP01003251.1_1 - 0.014 15.9 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CK2S PF15011.6 AAAP01003251.1_1 - 0.059 13.2 0.2 0.28 11.0 0.5 1.9 2 0 0 2 2 2 0 Casein Kinase 2 substrate AAA_22 PF13401.6 AAAP01003251.1_1 - 0.076 13.3 0.0 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 AAAP01003251.1_1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_21 PF13304.6 AAAP01003251.1_1 - 0.11 12.3 0.4 0.22 11.3 0.4 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Syntaxin-6_N PF09177.11 AAAP01003251.1_1 - 0.13 12.9 3.2 0.13 12.8 0.9 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AAA_7 PF12775.7 AAAP01003251.1_1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PI3K_P85_iSH2 PF16454.5 AAAP01003251.1_1 - 0.23 11.1 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 AAAP01003251.1_1 - 0.69 8.7 2.2 0.97 8.3 0.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Glutaminase PF04960.15 AAAP01003252.1_1 - 6.6e-69 232.3 0.0 7.4e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Glutaminase P-II PF00543.22 AAAP01003252.1_2 - 2.8e-42 143.5 1.1 3.2e-42 143.3 1.1 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF2344 PF10105.9 AAAP01003252.1_2 - 0.011 15.6 0.0 0.012 15.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF3240 PF11582.8 AAAP01003252.1_2 - 0.019 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Tae4 PF14113.6 AAAP01003252.1_2 - 0.022 15.0 0.0 0.049 13.9 0.0 1.4 1 1 1 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 YjeF_N PF03853.15 AAAP01003252.1_3 - 2.4e-24 86.1 0.7 3.7e-24 85.5 0.7 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus TonB_dep_Rec PF00593.24 AAAP01003253.1_1 - 1.8e-51 176.5 22.1 3.3e-51 175.7 22.1 1.4 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAAP01003253.1_1 - 9.3e-22 77.6 0.1 2.5e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Amidohydro_1 PF01979.20 AAAP01003254.1_1 - 1.9e-09 37.3 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Peripla_BP_3 PF13377.6 AAAP01003254.1_1 - 0.1 12.9 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 Periplasmic binding protein-like domain Ald_Xan_dh_C2 PF02738.18 AAAP01003254.1_2 - 5.9e-112 374.9 1.3 7.6e-112 374.5 1.3 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase ABC_tran PF00005.27 AAAP01003255.1_1 - 3.1e-11 43.9 0.0 3.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 AAAP01003255.1_1 - 0.00039 20.3 0.0 0.00046 20.1 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01003255.1_1 - 0.0011 19.4 0.1 0.0012 19.3 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003255.1_1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AAAP01003255.1_1 - 0.0023 17.9 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 AAAP01003255.1_1 - 0.0032 18.0 0.0 0.0042 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AAAP01003255.1_1 - 0.0038 16.7 0.0 0.0045 16.4 0.0 1.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AAAP01003255.1_1 - 0.0079 16.2 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAAP01003255.1_1 - 0.011 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003255.1_1 - 0.014 15.5 0.1 0.026 14.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAAP01003255.1_1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 AAAP01003255.1_1 - 0.02 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 AAAP01003255.1_1 - 0.072 13.3 0.0 0.091 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003255.1_1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 AAAP01003255.1_1 - 0.09 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AAAP01003255.1_1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01003255.1_1 - 0.16 12.3 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 AAAP01003255.1_1 - 0.29 11.7 0.1 0.29 11.7 0.1 1.4 2 0 0 2 2 1 0 AAA domain cNMP_binding PF00027.29 AAAP01003255.1_2 - 8.6e-19 67.4 0.0 1.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003255.1_2 - 1.9e-10 40.5 0.3 3.9e-10 39.5 0.3 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain G6PD_C PF02781.16 AAAP01003256.1_1 - 5.2e-110 367.2 0.0 6.2e-110 366.9 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AAAP01003256.1_1 - 3.7e-32 112.4 0.0 6.5e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Iso_dh PF00180.20 AAAP01003256.1_2 - 0.00035 19.8 0.0 0.00037 19.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MCPsignal PF00015.21 AAAP01003257.1_1 - 2.7e-28 98.9 26.7 2.7e-28 98.9 26.7 4.5 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAAP01003257.1_1 - 1.6e-27 96.2 0.0 1.6e-27 96.2 0.0 3.4 3 1 1 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003257.1_1 - 0.00048 20.5 0.2 0.00048 20.5 0.2 4.3 3 2 1 4 4 4 1 HAMP domain GCN5L1 PF06320.13 AAAP01003257.1_1 - 0.1 12.8 16.7 0.033 14.3 1.7 4.8 4 2 2 6 6 6 0 GCN5-like protein 1 (GCN5L1) DUF948 PF06103.11 AAAP01003257.1_1 - 0.11 12.8 30.7 0.32 11.3 3.8 6.5 3 2 5 8 8 8 0 Bacterial protein of unknown function (DUF948) DUF1805 PF08827.11 AAAP01003257.1_1 - 0.14 12.5 5.4 0.094 13.1 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DUF1664 PF07889.12 AAAP01003257.1_1 - 0.35 10.9 11.9 2.8 8.0 0.5 4.6 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 AAAP01003257.1_1 - 1.9 8.3 5.0 3.1 7.6 0.3 3.4 3 1 1 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain AAA_13 PF13166.6 AAAP01003257.1_1 - 2.1 6.9 6.8 0.61 8.6 3.7 1.6 2 0 0 2 2 2 0 AAA domain Vps53_N PF04100.12 AAAP01003257.1_1 - 6.9 5.5 10.9 7.5 5.4 0.7 2.3 1 1 2 3 3 3 0 Vps53-like, N-terminal PAS_3 PF08447.12 AAAP01003258.1_2 - 3.3e-11 43.3 0.0 6.5e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01003258.1_2 - 3.6e-10 40.0 0.0 5.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003258.1_2 - 1.4e-06 28.5 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003258.1_2 - 2.5e-06 27.4 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003258.1_2 - 0.029 14.4 0.0 0.074 13.1 0.0 1.8 1 0 0 1 1 1 0 PAS domain Response_reg PF00072.24 AAAP01003258.1_3 - 2.2e-06 27.8 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 AAAP01003258.1_3 - 0.0032 17.7 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Hpt domain Transpeptidase PF00905.22 AAAP01003259.1_1 - 2.5e-28 99.2 0.0 4.6e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Beta-lactamase2 PF13354.6 AAAP01003259.1_1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family Transgly PF00912.22 AAAP01003259.1_2 - 9.2e-17 61.1 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase DDE_Tnp_1 PF01609.21 AAAP01003260.1_2 - 1.4e-09 37.9 5.3 9.9e-09 35.2 5.3 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAAP01003260.1_2 - 1.8e-08 34.6 7.3 3.9e-08 33.6 7.3 1.6 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003260.1_2 - 0.0024 17.5 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4405 PF14358.6 AAAP01003261.1_1 - 0.072 13.6 2.4 0.15 12.7 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) Tox-REase-5 PF15648.6 AAAP01003261.1_1 - 0.22 12.1 0.0 0.26 11.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 SGL PF08450.12 AAAP01003261.1_2 - 5e-14 52.5 0.0 5.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 AAAP01003261.1_2 - 0.0013 19.1 3.8 0.011 16.2 2.6 2.6 2 1 0 2 2 2 1 PQQ-like domain NHL PF01436.21 AAAP01003261.1_2 - 0.011 15.7 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 0 NHL repeat Phytase-like PF13449.6 AAAP01003261.1_2 - 0.049 13.6 0.0 1.2 9.1 0.0 2.0 1 1 1 2 2 2 0 Esterase-like activity of phytase Str_synth PF03088.16 AAAP01003261.1_2 - 0.16 12.1 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Strictosidine synthase MG1 PF17790.1 AAAP01003261.1_2 - 0.23 11.9 0.0 0.46 10.9 0.0 1.4 2 0 0 2 2 2 0 Macroglobulin domain MG1 SGL PF08450.12 AAAP01003261.1_3 - 0.0014 18.3 0.0 0.0081 15.8 0.0 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Cyclophil_like2 PF18050.1 AAAP01003261.1_4 - 7.6e-36 122.6 0.0 9.2e-36 122.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like family Cyclophil_like PF04126.13 AAAP01003261.1_4 - 0.0055 16.5 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin-like adh_short_C2 PF13561.6 AAAP01003261.1_5 - 1.1e-23 84.0 0.0 1.2e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003261.1_5 - 0.0015 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 AAAP01003262.1_1 - 1.7e-32 112.2 0.8 2.8e-32 111.4 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003262.1_1 - 1.4e-27 95.7 1.1 1.1e-26 92.9 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AAAP01003262.1_1 - 3e-21 76.9 0.0 5.1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.9 AAAP01003262.1_1 - 0.089 12.9 0.2 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Cupin_5 PF06172.11 AAAP01003262.1_2 - 1.1e-47 161.8 0.0 1.2e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Amidohydro_1 PF01979.20 AAAP01003263.1_1 - 5.9e-09 35.7 0.0 5.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003263.1_1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family UreE_C PF05194.12 AAAP01003263.1_2 - 5.3e-27 94.1 7.0 7.9e-27 93.6 7.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreE_N PF02814.15 AAAP01003263.1_2 - 1e-12 47.5 5.3 1.8e-12 46.7 5.3 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain Glyco_transf_21 PF13506.6 AAAP01003263.1_2 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 UreF PF01730.16 AAAP01003263.1_3 - 1.3e-34 119.6 10.6 1.8e-34 119.2 10.6 1.2 1 0 0 1 1 1 1 UreF acVLRF1 PF18859.1 AAAP01003263.1_3 - 0.49 10.7 5.6 1.3 9.3 0.2 2.2 1 1 1 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor cobW PF02492.19 AAAP01003263.1_4 - 3.3e-36 124.5 0.0 4.3e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AAAP01003263.1_4 - 0.0017 17.4 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 AAAP01003263.1_4 - 0.0036 17.3 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003263.1_4 - 0.011 16.2 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAAP01003263.1_4 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 AAAP01003263.1_4 - 0.035 14.0 0.0 0.32 10.9 0.0 2.1 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 AAAP01003263.1_4 - 0.06 12.9 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AAAP01003263.1_4 - 0.087 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 AAAP01003263.1_4 - 0.1 13.1 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AAAP01003263.1_4 - 0.11 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003263.1_4 - 0.14 12.3 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 AAAP01003263.1_4 - 0.15 11.6 0.0 0.92 9.0 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 AAAP01003263.1_4 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AAAP01003263.1_4 - 0.17 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Roc PF08477.13 AAAP01003263.1_4 - 0.24 11.6 0.0 1.1 9.5 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pribosyl_synth PF14572.6 AAAP01003265.1_1 - 2.2e-21 76.8 0.4 3.4e-21 76.1 0.4 1.3 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AAAP01003265.1_1 - 4.9e-17 61.9 0.7 7.2e-17 61.4 0.7 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAAP01003265.1_1 - 4.2e-05 23.1 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AAAP01003265.1_1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase NMT1 PF09084.11 AAAP01003266.1_2 - 8.5e-10 38.9 0.2 1.1e-09 38.6 0.2 1.1 1 0 0 1 1 1 1 NMT1/THI5 like TraW_N PF12477.8 AAAP01003266.1_2 - 0.43 10.6 4.9 0.98 9.5 3.0 2.2 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal LysR_substrate PF03466.20 AAAP01003266.1_3 - 8.9e-31 106.9 5.9 1.2e-30 106.4 5.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003266.1_3 - 1.4e-19 69.8 0.8 3.6e-19 68.4 0.8 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CBS PF00571.28 AAAP01003266.1_3 - 0.13 12.7 0.1 0.51 10.8 0.1 2.0 1 0 0 1 1 1 0 CBS domain Amidohydro_3 PF07969.11 AAAP01003266.1_4 - 0.0079 15.7 1.1 0.013 15.0 0.7 1.5 1 1 0 1 1 1 1 Amidohydrolase family NusB PF01029.18 AAAP01003267.1_1 - 1.4e-10 41.5 0.0 1.8e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 NusB family RP1-2 PF12042.8 AAAP01003267.1_1 - 0.4 10.5 5.8 0.62 9.9 5.8 1.3 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain DUF1674 PF07896.12 AAAP01003267.1_2 - 2.9e-13 50.1 1.1 3.9e-13 49.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) MerR-DNA-bind PF09278.11 AAAP01003267.1_2 - 0.055 14.0 1.5 0.068 13.7 1.5 1.2 1 0 0 1 1 1 0 MerR, DNA binding Potass_KdpF PF09604.10 AAAP01003267.1_5 - 6.3e-12 45.2 3.7 7e-12 45.0 3.7 1.1 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) KdpA PF03814.15 AAAP01003267.1_6 - 5.6e-39 133.8 0.0 6.1e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit DUF4282 PF14110.6 AAAP01003268.1_2 - 1.4 9.7 11.8 0.19 12.5 7.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF4633 PF15464.6 AAAP01003268.1_3 - 0.015 15.4 1.1 0.018 15.2 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) DUF4140 PF13600.6 AAAP01003268.1_3 - 0.042 14.3 3.3 0.047 14.1 3.3 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Orthopox_F8 PF05886.11 AAAP01003268.1_3 - 0.24 11.6 1.6 0.35 11.0 1.6 1.3 1 0 0 1 1 1 0 Orthopoxvirus F8 protein DUF4226 PF10774.9 AAAP01003268.1_4 - 1 9.6 8.0 1.9 8.8 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) Bac_luciferase PF00296.20 AAAP01003269.1_1 - 8.3e-72 242.3 0.1 9.8e-72 242.0 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Phage_TAC_11 PF11836.8 AAAP01003269.1_1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 Isochorismatase PF00857.20 AAAP01003269.1_2 - 8.4e-07 29.3 0.0 9.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 AAAP01003269.1_3 - 1.6e-30 106.5 0.0 1.9e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family CsgG PF03783.14 AAAP01003270.1_1 - 2.9e-32 111.7 0.0 4e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Curli production assembly/transport component CsgG FlgT_C PF16538.5 AAAP01003270.1_1 - 0.075 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, C-terminal domain LpxI_C PF06230.11 AAAP01003271.1_1 - 0.00035 20.4 0.0 0.00035 20.4 0.0 1.1 1 0 0 1 1 1 1 LpxI C-terminal domain LpxI_N PF17930.1 AAAP01003271.1_2 - 9.2e-24 83.8 0.1 1.1e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 LpxI N-terminal domain Acetyltransf_11 PF13720.6 AAAP01003271.1_3 - 1.1e-24 86.7 0.0 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AAAP01003271.1_3 - 3.4e-24 83.6 17.5 5e-08 32.4 0.2 6.4 3 2 2 7 7 7 7 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003271.1_3 - 0.00018 21.2 13.5 0.011 15.5 0.4 5.4 4 2 2 6 6 6 4 Hexapeptide repeat of succinyl-transferase DUF2407_C PF13373.6 AAAP01003271.1_3 - 0.2 11.8 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain FabA PF07977.13 AAAP01003271.1_4 - 1.8e-26 92.4 0.1 2e-26 92.3 0.1 1.0 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 AAAP01003271.1_4 - 5.9e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 1 1 2 2 2 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAAP01003271.1_4 - 0.00017 21.1 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain BPD_transp_2 PF02653.16 AAAP01003272.1_1 - 7.8e-29 100.7 35.6 8.8e-29 100.5 35.6 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AAAP01003272.1_2 - 2.6e-26 92.8 0.0 4.3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01003272.1_2 - 3e-12 46.2 0.7 5.2e-12 45.4 0.7 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_27 PF13514.6 AAAP01003272.1_2 - 2.5e-05 24.0 0.1 0.0003 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 AAAP01003272.1_2 - 2.9e-05 24.0 0.8 0.00028 20.8 0.2 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003272.1_2 - 0.00028 20.6 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003272.1_2 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AAAP01003272.1_2 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003272.1_2 - 0.0068 16.8 1.2 0.014 15.8 1.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAAP01003272.1_2 - 0.017 15.7 0.1 0.024 15.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003272.1_2 - 0.017 15.2 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AAAP01003272.1_2 - 0.029 14.1 0.5 0.14 11.9 0.5 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AAAP01003272.1_2 - 0.054 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 AAAP01003272.1_2 - 0.16 11.7 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF2813 PF11398.8 AAAP01003272.1_2 - 0.17 11.1 0.0 0.35 10.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) IIGP PF05049.13 AAAP01003272.1_2 - 0.3 10.1 0.1 0.47 9.4 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 AAAP01003272.1_3 - 7e-30 104.3 0.0 9.1e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003272.1_3 - 6.5e-12 45.9 2.9 6.9e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003272.1_3 - 3.2e-05 24.4 2.4 8e-05 23.1 2.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AAAP01003272.1_3 - 0.00033 20.7 0.0 0.00058 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 AAAP01003272.1_3 - 0.00058 20.0 0.3 0.0061 16.8 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AAAP01003272.1_3 - 0.0016 17.9 0.2 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01003272.1_3 - 0.0033 17.3 0.5 0.0063 16.4 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AAAP01003272.1_3 - 0.0055 16.4 0.1 0.0095 15.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 AAAP01003272.1_3 - 0.013 15.2 0.3 2.6 7.8 0.0 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 AAAP01003272.1_3 - 0.026 13.5 0.4 0.039 12.9 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 AAAP01003272.1_3 - 0.026 14.6 0.3 0.046 13.8 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Mg_chelatase PF01078.21 AAAP01003272.1_3 - 0.063 12.7 0.1 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAAP01003272.1_3 - 0.096 12.6 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AAAP01003272.1_3 - 0.11 12.7 1.5 4.8 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 AAAP01003272.1_3 - 0.2 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 AAAP01003272.1_3 - 0.21 11.5 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 AAAP01003272.1_3 - 0.33 10.7 3.3 0.2 11.4 0.5 1.9 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAAP01003272.1_3 - 0.37 10.0 0.5 1.1 8.4 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 AAAP01003272.1_3 - 0.48 10.7 2.0 3.1 8.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain TauE PF01925.19 AAAP01003273.1_1 - 9.7e-48 162.8 43.0 1.1e-47 162.7 43.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Rick_17kDa_Anti PF05433.15 AAAP01003273.1_1 - 0.77 9.7 18.3 0.56 10.1 3.4 3.3 3 0 0 3 3 3 0 Glycine zipper 2TM domain B12D PF06522.11 AAAP01003273.1_1 - 0.78 9.6 0.1 0.78 9.6 0.1 2.7 2 1 1 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Lactamase_B PF00753.27 AAAP01003273.1_2 - 4.6e-22 79.0 3.0 6.2e-22 78.6 3.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TonB_dep_Rec PF00593.24 AAAP01003274.1_1 - 1e-57 197.1 17.9 1.2e-57 196.9 17.9 1.0 1 0 0 1 1 1 1 TonB dependent receptor PepSY_TM PF03929.16 AAAP01003274.1_2 - 2.4e-46 158.7 8.4 2.8e-46 158.5 8.4 1.0 1 0 0 1 1 1 1 PepSY-associated TM region DUF2244 PF10003.9 AAAP01003274.1_2 - 0.47 10.1 4.7 1.3 8.7 0.4 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF1217 PF06748.12 AAAP01003275.1_1 - 5.9e-25 88.0 5.2 3.9e-23 82.2 2.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1217) PilZ PF07238.14 AAAP01003275.1_3 - 3e-09 37.1 0.1 3.7e-09 36.8 0.1 1.0 1 0 0 1 1 1 1 PilZ domain Flagellin_N PF00669.20 AAAP01003275.1_4 - 1.6e-20 73.6 14.0 2.1e-20 73.2 14.0 1.2 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region Siah-Interact_N PF09032.11 AAAP01003275.1_4 - 0.032 14.5 0.1 0.063 13.6 0.1 1.5 1 0 0 1 1 1 0 Siah interacting protein, N terminal V-SNARE PF05008.15 AAAP01003275.1_4 - 0.063 13.7 0.1 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PDZ_2 PF13180.6 AAAP01003276.1_1 - 3.8e-22 78.4 0.7 2.5e-11 43.7 0.2 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 AAAP01003276.1_1 - 5.4e-12 45.4 0.8 1.2e-09 37.8 0.7 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AAAP01003276.1_1 - 7.7e-12 45.4 0.3 2.2e-10 40.7 0.4 2.1 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 AAAP01003276.1_1 - 9.4e-07 28.7 0.7 0.00052 19.9 0.2 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 AAAP01003276.1_1 - 0.01 16.2 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Trypsin_2 PF13365.6 AAAP01003276.1_2 - 2.5e-29 103.1 2.1 2.5e-29 103.1 2.1 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAAP01003276.1_2 - 4.4e-10 39.7 0.0 8.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.13 AAAP01003276.1_2 - 0.022 14.0 0.3 0.032 13.4 0.3 1.1 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF2459 PF09601.10 AAAP01003276.1_3 - 2.1e-39 135.1 0.0 2.6e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2459) GTP_EFTU PF00009.27 AAAP01003277.1_1 - 1e-27 97.0 0.6 1.1e-27 96.8 0.6 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosomal_S7 PF00177.21 AAAP01003277.1_2 - 2e-67 225.4 4.8 2.3e-67 225.3 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nup153 PF08604.10 AAAP01003277.1_2 - 0.0043 15.9 0.2 0.0052 15.6 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup153-like Mak_N_cap PF18085.1 AAAP01003277.1_2 - 0.065 14.3 0.1 0.11 13.5 0.1 1.5 1 1 0 1 1 1 0 Maltokinase N-terminal cap domain Ribosom_S12_S23 PF00164.25 AAAP01003277.1_3 - 3.1e-42 142.8 2.1 3.5e-42 142.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SbcCD_C PF13558.6 AAAP01003277.1_4 - 9e-14 51.5 0.0 2.8e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Arabinose_Isome PF02610.15 AAAP01003277.1_4 - 0.014 14.6 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 L-arabinose isomerase Aconitase PF00330.20 AAAP01003278.1_1 - 1.5e-122 410.0 0.0 1.8e-122 409.7 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) ArgJ PF01960.18 AAAP01003279.1_1 - 2.2e-38 132.0 2.2 2.6e-38 131.7 2.2 1.0 1 0 0 1 1 1 1 ArgJ family Semialdhyde_dh PF01118.24 AAAP01003279.1_2 - 1.2e-21 77.4 0.0 5.6e-21 75.2 0.0 2.1 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AAAP01003279.1_2 - 6.7e-17 62.1 0.0 1.3e-16 61.2 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain NAD_binding_10 PF13460.6 AAAP01003279.1_2 - 8.8 6.2 9.2 1.2 9.0 0.6 2.4 3 0 0 3 3 3 0 NAD(P)H-binding Cytochrome_C7 PF14522.6 AAAP01003280.1_2 - 4.9e-11 42.5 13.9 1.3e-06 28.3 3.2 3.3 2 2 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 AAAP01003280.1_2 - 6.9e-10 39.3 6.6 2.8e-05 24.5 0.9 2.5 2 1 0 2 2 2 2 Cytochrome c3 Cytochrom_CIII PF02085.16 AAAP01003280.1_2 - 1.4e-07 31.8 15.8 0.00043 20.6 2.1 3.7 1 1 0 2 2 2 2 Class III cytochrome C family Paired_CXXCH_1 PF09699.10 AAAP01003280.1_2 - 0.0078 15.9 21.3 0.11 12.3 2.4 4.4 3 2 1 4 4 4 3 Doubled CXXCH motif (Paired_CXXCH_1) PHD_4 PF16866.5 AAAP01003280.1_2 - 0.026 14.6 6.5 0.93 9.6 0.0 3.7 4 1 0 4 4 4 0 PHD-finger zf-CHY PF05495.12 AAAP01003280.1_2 - 0.098 13.2 10.6 0.41 11.2 0.1 3.3 3 1 1 4 4 4 0 CHY zinc finger DZR PF12773.7 AAAP01003280.1_2 - 0.14 12.2 9.0 0.16 12.0 1.0 2.7 3 0 0 3 3 3 0 Double zinc ribbon zf-C4H2 PF10146.9 AAAP01003280.1_2 - 0.14 12.4 1.5 0.24 11.7 0.1 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein DUF1924 PF09086.11 AAAP01003280.1_2 - 0.16 12.3 9.6 4.4 7.7 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1924) Zn-ribbon_8 PF09723.10 AAAP01003280.1_2 - 0.38 10.9 9.1 0.79 9.9 1.1 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Thioredoxin_3 PF13192.6 AAAP01003280.1_2 - 0.83 9.7 2.4 11 6.2 0.2 2.4 2 0 0 2 2 2 0 Thioredoxin domain DUF3365 PF11845.8 AAAP01003280.1_2 - 0.93 9.8 13.8 8.7 6.6 0.3 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3365) TraT PF05818.12 AAAP01003281.1_1 - 1.2 8.8 5.2 1.5 8.4 5.2 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Carbam_trans_C PF16861.5 AAAP01003281.1_2 - 8.9e-66 220.7 0.0 1.3e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 AAAP01003281.1_2 - 9.8e-26 91.2 0.0 1.4e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Sua5_yciO_yrdC PF01300.18 AAAP01003281.1_2 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination Proton_antipo_M PF00361.20 AAAP01003282.1_1 - 2.6e-68 230.4 19.5 2.6e-68 230.4 19.5 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAAP01003282.1_1 - 2.6e-08 33.8 1.3 8.4e-08 32.2 0.3 2.3 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NMT1 PF09084.11 AAAP01003283.1_1 - 1.5e-10 41.4 0.0 2.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.12 AAAP01003283.1_1 - 8.9e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 AAAP01003283.1_1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 AAAP01003283.1_1 - 2.3e-05 24.2 0.1 3.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 AAAP01003283.1_1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01003283.1_1 - 0.0073 15.9 0.1 0.025 14.2 0.1 1.9 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein ACT_7 PF13840.6 AAAP01003283.1_1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 ACT domain Bac_luciferase PF00296.20 AAAP01003283.1_3 - 4.2e-12 46.1 3.5 4.8e-12 45.9 3.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1925 PF09094.11 AAAP01003283.1_3 - 0.18 12.1 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) EamA PF00892.20 AAAP01003284.1_1 - 2.5e-11 43.9 17.2 3.2e-11 43.6 17.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF1801 PF08818.11 AAAP01003284.1_2 - 4.1e-12 46.4 0.0 5.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) MMR_HSR1 PF01926.23 AAAP01003284.1_3 - 1.3e-47 160.6 0.1 3.9e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01003284.1_3 - 6.7e-21 74.4 0.0 4.1e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 AAAP01003284.1_3 - 2.9e-15 56.7 0.1 0.0024 18.0 0.0 4.2 3 1 1 4 4 4 4 Dynamin family GTP_EFTU PF00009.27 AAAP01003284.1_3 - 2.3e-12 46.9 0.1 9.7e-08 31.8 0.0 5.1 4 2 0 4 4 4 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 AAAP01003284.1_3 - 4.3e-10 39.3 0.1 6.8e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AAAP01003284.1_3 - 1.9e-08 34.4 0.0 0.0028 17.6 0.0 3.1 2 1 0 2 2 2 2 RsgA GTPase Roc PF08477.13 AAAP01003284.1_3 - 5.2e-07 29.9 0.0 0.028 14.7 0.0 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase KH_dom-like PF14714.6 AAAP01003284.1_3 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal AAA_16 PF13191.6 AAAP01003284.1_3 - 3.9e-06 27.3 0.2 0.11 12.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain Ras PF00071.22 AAAP01003284.1_3 - 2.9e-05 23.7 0.0 0.089 12.4 0.0 2.5 2 1 0 2 2 2 2 Ras family ABC_tran PF00005.27 AAAP01003284.1_3 - 7.4e-05 23.3 0.0 0.2 12.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 AAAP01003284.1_3 - 0.00039 20.6 0.3 0.031 14.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAAP01003284.1_3 - 0.00051 19.8 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AAAP01003284.1_3 - 0.00092 18.7 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein SRPRB PF09439.10 AAAP01003284.1_3 - 0.0011 18.4 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 AAAP01003284.1_3 - 0.0036 17.6 0.0 0.2 11.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.6 AAAP01003284.1_3 - 0.0054 17.0 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Spore_IV_A PF09547.10 AAAP01003284.1_3 - 0.0065 15.5 0.1 0.026 13.5 0.1 1.9 2 1 1 3 3 3 1 Stage IV sporulation protein A (spore_IV_A) NTPase_1 PF03266.15 AAAP01003284.1_3 - 0.0095 15.9 0.1 2.2 8.2 0.0 2.8 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 AAAP01003284.1_3 - 0.015 15.6 0.0 8.3 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Arf PF00025.21 AAAP01003284.1_3 - 0.021 14.2 0.0 6.5 6.2 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 AAAP01003284.1_3 - 0.043 13.7 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 AAAP01003284.1_3 - 0.049 13.4 0.0 19 5.1 0.0 2.8 2 1 1 3 3 3 0 P-loop containing region of AAA domain GBP PF02263.19 AAAP01003284.1_3 - 0.075 12.3 0.0 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain ATPase_2 PF01637.18 AAAP01003284.1_3 - 0.083 12.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NOG1 PF06858.14 AAAP01003284.1_3 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_18 PF13238.6 AAAP01003284.1_3 - 0.11 13.1 0.0 26 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAAP01003284.1_3 - 0.14 11.3 0.0 1.8 7.7 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 AAAP01003284.1_3 - 0.19 11.6 0.0 46 3.9 0.0 3.2 3 0 0 3 3 3 0 NACHT domain MeaB PF03308.16 AAAP01003284.1_3 - 0.65 8.9 4.7 6.4 5.7 0.0 3.0 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1194 PF06707.11 AAAP01003285.1_1 - 1.5e-28 99.4 0.1 1.9e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) VWA_2 PF13519.6 AAAP01003285.1_1 - 0.0055 17.3 0.0 0.0075 16.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AAAP01003285.1_1 - 0.054 13.7 0.0 0.061 13.6 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain ApbE PF02424.15 AAAP01003285.1_2 - 7.4e-60 202.6 0.0 9.5e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 ApbE family TAT_signal PF10518.9 AAAP01003285.1_2 - 0.0036 17.1 4.0 0.0036 17.1 4.0 2.8 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_5 PF12801.7 AAAP01003285.1_3 - 8.9e-15 54.4 24.4 2e-13 50.1 5.0 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain PetM PF08041.11 AAAP01003285.1_3 - 3.7 7.2 8.2 0.2 11.3 1.4 2.4 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Fer4 PF00037.27 AAAP01003285.1_3 - 9.5 6.2 12.8 33 4.5 0.4 4.5 5 0 0 5 5 5 0 4Fe-4S binding domain DUF983 PF06170.12 AAAP01003286.1_1 - 3.4e-13 49.8 4.7 3.9e-13 49.6 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF983) Aminotran_1_2 PF00155.21 AAAP01003286.1_2 - 7.4e-34 117.5 0.0 8.5e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAAP01003286.1_2 - 1.9e-05 23.8 0.0 2.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01003286.1_2 - 0.081 11.4 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAAP01003286.1_3 - 7.7e-15 54.9 0.0 8.3e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cyt_bd_oxida_I PF01654.17 AAAP01003286.1_4 - 2.1e-94 316.5 20.8 2.3e-94 316.4 20.8 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I ThiW PF09512.10 AAAP01003286.1_4 - 0.027 14.6 2.0 0.027 14.6 2.0 2.5 2 1 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Legionella_OMP PF05150.12 AAAP01003286.1_4 - 0.063 12.2 1.0 1.2 8.0 0.1 2.1 1 1 1 2 2 2 0 Legionella pneumophila major outer membrane protein precursor CcmD PF04995.14 AAAP01003286.1_4 - 0.15 12.2 2.3 0.19 11.8 0.4 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) RHH_1 PF01402.21 AAAP01003287.1_2 - 5.5e-05 23.0 2.1 0.00055 19.8 0.1 2.4 2 1 0 2 2 2 1 Ribbon-helix-helix protein, copG family MerR_2 PF13591.6 AAAP01003287.1_2 - 0.017 14.9 0.1 0.035 14.0 0.1 1.6 1 1 1 2 2 2 0 MerR HTH family regulatory protein Dynamitin PF04912.14 AAAP01003287.1_2 - 0.081 12.2 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Dynamitin CcdA PF07362.12 AAAP01003287.1_2 - 0.083 13.3 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA T2SSE PF00437.20 AAAP01003287.1_3 - 4.4e-75 252.3 0.3 4.9e-75 252.1 0.3 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 AAAP01003287.1_3 - 0.00029 20.2 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin TrwB_AAD_bind PF10412.9 AAAP01003287.1_3 - 0.00073 18.6 0.1 0.0011 17.9 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 AAAP01003287.1_3 - 0.00083 19.8 0.3 0.0017 18.7 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 AAAP01003287.1_3 - 0.00098 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_28 PF13521.6 AAAP01003287.1_3 - 0.0019 18.5 0.1 0.0031 17.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01003287.1_3 - 0.0031 17.6 0.1 0.005 16.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AAAP01003287.1_3 - 0.0038 16.8 0.1 0.0054 16.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 AAAP01003287.1_3 - 0.0058 16.4 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AAAP01003287.1_3 - 0.012 15.0 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AAAP01003287.1_3 - 0.019 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AAAP01003287.1_3 - 0.025 14.9 0.3 0.034 14.5 0.3 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01003287.1_3 - 0.046 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 AAAP01003287.1_3 - 0.055 14.0 0.0 0.067 13.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter RecA PF00154.21 AAAP01003287.1_3 - 0.087 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein CbiA PF01656.23 AAAP01003287.1_3 - 0.1 12.6 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_ATPase PF09818.9 AAAP01003287.1_3 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 AAAP01003287.1_3 - 0.13 11.9 0.4 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Septin PF00735.18 AAAP01003287.1_3 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_32 PF13654.6 AAAP01003287.1_3 - 0.22 10.2 0.1 0.4 9.4 0.0 1.3 2 0 0 2 2 2 0 AAA domain TrbC PF04956.13 AAAP01003287.1_4 - 1.8e-23 82.6 6.3 2e-23 82.4 6.3 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF418 PF04235.12 AAAP01003287.1_4 - 0.22 11.5 3.8 0.11 12.4 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF418) DNA_pol_A PF00476.20 AAAP01003288.1_1 - 8.8e-146 485.8 0.0 1e-145 485.6 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 AAAP01003288.1_1 - 0.00044 20.0 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Endonuclease_5 PF04493.14 AAAP01003288.1_2 - 4.7e-67 225.5 0.0 5.8e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 AAAP01003288.1_2 - 0.0035 16.8 0.2 0.0076 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF99 YchF-GTPase_C PF06071.13 AAAP01003288.1_3 - 7.3e-39 131.8 0.0 1.2e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF933) adh_short_C2 PF13561.6 AAAP01003289.1_2 - 4.7e-52 176.9 3.8 6.7e-52 176.4 3.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003289.1_2 - 1.8e-47 161.3 3.7 2.8e-47 160.7 3.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003289.1_2 - 1e-11 45.0 5.2 5.1e-10 39.5 5.2 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003289.1_2 - 0.00032 20.2 0.5 0.00054 19.5 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AAA_PrkA PF08298.11 AAAP01003289.1_4 - 7e-08 31.8 0.0 7.8e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 PrkA AAA domain Na_sulph_symp PF00939.19 AAAP01003290.1_1 - 9.8e-24 84.2 15.5 1.2e-23 83.9 15.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AAAP01003290.1_1 - 1.1e-12 47.8 29.1 1.1e-12 47.8 29.1 1.8 1 1 0 1 1 1 1 Citrate transporter Sdh_cyt PF01127.22 AAAP01003290.1_2 - 7e-29 100.3 11.5 8.6e-29 100.0 11.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AAAP01003290.1_2 - 0.0029 17.7 2.5 0.004 17.3 2.0 1.5 1 1 0 1 1 1 1 Fumarate reductase subunit D Sdh_cyt PF01127.22 AAAP01003290.1_3 - 3.6e-10 39.9 2.8 4.4e-10 39.6 2.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Silic_transp PF03842.13 AAAP01003290.1_3 - 0.065 11.5 0.3 0.073 11.4 0.3 1.0 1 0 0 1 1 1 0 Silicon transporter DUF3043 PF11241.8 AAAP01003290.1_3 - 0.5 10.4 4.1 0.42 10.6 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Insulin_TMD PF17870.1 AAAP01003290.1_3 - 3.2 7.9 5.3 4 7.6 2.5 2.1 1 1 1 2 2 2 0 Insulin receptor trans-membrane segment Phage_integrase PF00589.22 AAAP01003291.1_1 - 3.1e-30 105.2 0.2 4.8e-30 104.6 0.2 1.3 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_4 PF14657.6 AAAP01003291.1_1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Integrase_1 PF12835.7 AAAP01003291.1_1 - 0.051 13.7 0.1 0.33 11.0 0.0 2.3 2 1 0 2 2 2 0 Integrase DUF2188 PF09954.9 AAAP01003291.1_1 - 0.11 12.7 0.0 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Acetyltransf_9 PF13527.7 AAAP01003292.1_5 - 0.0021 18.1 0.0 0.0043 17.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003292.1_5 - 0.0024 18.1 0.0 0.0025 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003292.1_5 - 0.01 16.2 0.0 0.037 14.5 0.0 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003292.1_5 - 0.044 13.7 0.0 0.12 12.3 0.0 1.5 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DNA_topoisoIV PF00521.20 AAAP01003293.1_1 - 1.3e-07 30.9 0.0 1.5e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_topoisoIV PF00521.20 AAAP01003293.1_2 - 1.7e-93 313.9 0.0 2.2e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAAP01003293.1_2 - 2.4e-09 36.5 0.3 0.0029 17.0 0.1 3.9 3 0 0 3 3 3 3 DNA gyrase C-terminal domain, beta-propeller Mus7 PF09462.10 AAAP01003293.1_2 - 0.081 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family DctP PF03480.13 AAAP01003293.1_3 - 5.9e-11 42.2 0.0 6.7e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 DUF1073 PF06381.11 AAAP01003294.1_1 - 6.5e-95 317.9 0.0 7.5e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1073) Tnp_22_dsRBD PF17490.2 AAAP01003294.1_1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Terminase_3C PF17288.2 AAAP01003294.1_2 - 3.1e-17 63.4 0.0 4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Terminase RNAseH like domain Terminase_3 PF04466.13 AAAP01003294.1_2 - 5.3e-06 26.1 0.1 7.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Phage terminase large subunit ketoacyl-synt PF00109.26 AAAP01003295.1_1 - 5.3e-17 62.2 0.0 6.3e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 AAAP01003295.1_2 - 1.4e-14 54.1 0.2 1.6e-14 54.0 0.2 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AAAP01003295.1_2 - 1.4e-05 25.3 0.5 1.6e-05 25.1 0.5 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L12_N PF16320.5 AAAP01003295.1_2 - 0.0026 17.4 1.4 0.0067 16.1 0.4 2.3 2 1 1 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DUF1493 PF07377.12 AAAP01003295.1_2 - 0.0041 17.6 0.2 0.0047 17.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) TerB PF05099.13 AAAP01003295.1_2 - 0.051 13.5 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB adh_short_C2 PF13561.6 AAAP01003295.1_3 - 1e-63 215.0 9.7 1.2e-63 214.8 9.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003295.1_3 - 4.3e-57 192.7 3.4 5.4e-57 192.4 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003295.1_3 - 3.4e-21 76.0 2.1 4.6e-21 75.5 2.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003295.1_3 - 2.3e-05 24.3 3.4 3.1e-05 24.0 3.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAAP01003295.1_3 - 3.3e-05 23.5 1.4 0.00039 19.9 1.6 2.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAAP01003295.1_3 - 5.5e-05 22.8 1.3 5.5e-05 22.8 1.3 1.8 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 AAAP01003295.1_3 - 0.0044 16.1 0.8 0.007 15.5 0.8 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAAP01003295.1_3 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Acyl_transf_1 PF00698.21 AAAP01003295.1_4 - 9e-21 74.7 4.0 1.1e-20 74.4 4.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DUF2958 PF11171.8 AAAP01003295.1_4 - 0.098 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) 4HBT PF03061.22 AAAP01003296.1_1 - 9.8e-20 70.7 0.6 1.2e-19 70.4 0.6 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAAP01003296.1_1 - 4.6e-05 23.8 0.1 4.9e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 AAAP01003296.1_1 - 0.0013 18.3 0.2 0.0018 17.8 0.1 1.3 1 1 0 1 1 1 1 MaoC like domain 4HBT_2 PF13279.6 AAAP01003296.1_1 - 0.025 15.1 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily MaoC_dehydrat_N PF13452.6 AAAP01003296.1_1 - 0.085 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Peptidase_C93 PF06035.11 AAAP01003296.1_2 - 1.2e-15 57.7 0.0 1.6e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial transglutaminase-like cysteine proteinase BTLCP MetJ PF01340.20 AAAP01003296.1_3 - 0.063 13.3 0.0 0.092 12.7 0.0 1.3 1 1 0 1 1 1 0 Met Apo-repressor, MetJ Response_reg PF00072.24 AAAP01003296.1_4 - 5.6e-13 49.0 0.0 6.3e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PG_binding_1 PF01471.18 AAAP01003297.1_1 - 1.6e-05 25.1 0.0 2.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DMT_YdcZ PF04657.13 AAAP01003297.1_2 - 4.1e-05 23.9 0.2 5.5e-05 23.5 0.1 1.3 2 0 0 2 2 2 1 Putative inner membrane exporter, YdcZ TPR_1 PF00515.28 AAAP01003297.1_3 - 0.0054 16.5 5.4 0.023 14.5 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003297.1_3 - 0.0075 16.2 2.5 0.033 14.2 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003297.1_3 - 0.034 15.0 5.1 0.034 15.0 5.1 3.5 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003297.1_3 - 0.042 14.4 6.1 0.042 14.4 6.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003297.1_3 - 1.1 9.9 29.1 1.7 9.4 11.5 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003297.1_3 - 3.9 7.8 13.7 1 9.6 1.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_lid_2 PF17863.1 AAAP01003298.1_1 - 3.6e-07 29.9 0.4 1.5e-06 27.9 0.1 1.8 1 1 1 2 2 2 2 AAA lid domain DUF5455 PF17537.2 AAAP01003298.1_1 - 0.15 12.5 0.0 0.21 12.0 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5455) VWA_2 PF13519.6 AAAP01003298.1_2 - 6.5e-05 23.5 0.0 0.0001 22.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF58 PF01882.18 AAAP01003298.1_2 - 0.0005 20.3 0.0 0.0015 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_CoxE PF05762.14 AAAP01003298.1_2 - 0.001 18.5 1.7 0.62 9.4 0.2 2.4 2 1 0 2 2 2 2 VWA domain containing CoxE-like protein DEAD PF00270.29 AAAP01003299.1_1 - 1.1e-21 77.4 0.0 1.4e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01003299.1_1 - 0.00018 21.5 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AbiEii PF08843.11 AAAP01003299.1_2 - 9.3e-43 146.9 0.1 1.1e-42 146.7 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system AbiEi_3_N PF17194.4 AAAP01003299.1_3 - 2.6e-06 27.3 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain AbiEi_4 PF13338.6 AAAP01003299.1_3 - 2.3e-05 24.4 0.8 7.7e-05 22.8 0.4 2.1 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin HEAT_PBS PF03130.16 AAAP01003299.1_3 - 3 8.8 8.7 11 7.0 0.7 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat VWA_2 PF13519.6 AAAP01003300.1_1 - 3.4e-10 40.5 0.0 5.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AAAP01003300.1_1 - 0.0007 19.9 0.0 0.00082 19.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Abhydrolase_6 PF12697.7 AAAP01003300.1_2 - 1e-23 85.1 12.6 1e-23 85.1 12.6 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003300.1_2 - 9.4e-17 61.5 0.0 1.7e-13 50.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01003300.1_2 - 1.2e-10 41.1 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AAAP01003300.1_2 - 0.00011 21.0 0.0 0.002 16.9 0.0 2.2 2 1 0 2 2 2 1 Ndr family Amino_oxidase PF01593.24 AAAP01003300.1_3 - 9.8e-24 84.4 0.1 1.2e-23 84.1 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AAAP01003300.1_3 - 1.3e-13 51.0 0.3 3.3e-13 49.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003300.1_3 - 2.8e-07 30.4 2.7 0.00082 19.1 0.2 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003300.1_3 - 7.4e-07 28.6 0.8 3.7e-06 26.3 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01003300.1_3 - 3.4e-06 26.5 0.2 8.9e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003300.1_3 - 0.0014 19.2 1.4 0.0047 17.5 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003300.1_3 - 0.0019 17.0 0.0 0.0052 15.5 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 AAAP01003300.1_3 - 0.0029 17.0 0.6 0.012 14.9 0.7 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAAP01003300.1_3 - 0.016 14.4 0.3 0.025 13.8 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 AAAP01003300.1_3 - 0.026 14.5 0.8 0.57 10.2 0.4 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 AAAP01003300.1_3 - 0.033 13.3 0.6 0.43 9.6 0.4 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A MCRA PF06100.11 AAAP01003300.1_3 - 0.037 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 AAAP01003300.1_3 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family ResIII PF04851.15 AAAP01003301.1_1 - 2.2e-13 50.6 0.0 2.4e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AAAP01003301.1_1 - 8.2e-07 29.0 0.0 9.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 AAAP01003301.1_1 - 0.0038 17.0 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 AAAP01003301.1_1 - 0.0049 16.6 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AAAP01003301.1_1 - 0.028 13.5 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AAAP01003301.1_1 - 0.058 13.3 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 AAAP01003301.1_1 - 0.086 11.7 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF1376 PF07120.11 AAAP01003301.1_2 - 0.029 14.7 0.1 0.072 13.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1376) HTH_29 PF13551.6 AAAP01003301.1_2 - 0.47 10.5 2.7 0.8 9.8 0.1 2.6 2 1 1 3 3 3 0 Winged helix-turn helix CDPS PF16715.5 AAAP01003301.1_3 - 0.085 12.5 1.0 0.089 12.4 1.0 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase DNA_methylase PF00145.17 AAAP01003301.1_4 - 2.2e-05 24.0 0.0 2.4e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Phenol_MetA_deg PF13557.6 AAAP01003302.1_1 - 3.7e-21 76.2 2.0 4.2e-21 76.0 2.0 1.0 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation Phenol_MetA_deg PF13557.6 AAAP01003302.1_2 - 0.11 12.5 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation CBS PF00571.28 AAAP01003302.1_3 - 8.7e-27 93.3 4.8 5e-14 52.5 0.9 2.2 2 0 0 2 2 2 2 CBS domain HicA_toxin PF07927.12 AAAP01003302.1_3 - 0.17 12.0 0.5 25 5.0 0.4 2.7 2 1 1 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, XdhC_CoxI PF02625.16 AAAP01003302.1_3 - 2 8.7 6.6 6.1 7.1 2.0 3.1 1 1 1 2 2 2 0 XdhC and CoxI family Patatin PF01734.22 AAAP01003302.1_4 - 3.3e-09 37.2 0.1 6.5e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Bac_surface_Ag PF01103.23 AAAP01003303.1_1 - 1e-11 44.9 0.0 1.2e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 AAAP01003303.1_2 - 2.7e-50 168.9 10.1 3.2e-13 50.1 0.0 5.6 5 1 0 5 5 5 5 Surface antigen variable number repeat Bac_surface_Ag PF01103.23 AAAP01003303.1_2 - 2.5e-19 70.0 0.5 2.5e-19 70.0 0.5 1.6 2 0 0 2 2 2 1 Surface antigen POTRA_1 PF08478.10 AAAP01003303.1_2 - 1.7e-05 25.0 0.3 0.57 10.5 0.0 4.0 4 0 0 4 4 4 2 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AAAP01003303.1_2 - 0.0046 16.8 0.3 0.72 9.7 0.0 4.1 6 0 0 6 6 6 1 POTRA domain, ShlB-type T2SSE PF00437.20 AAAP01003304.1_1 - 1.3e-19 70.3 0.0 2.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Fer4_NifH PF00142.18 AAAP01003304.1_2 - 0.00027 20.5 0.0 0.00032 20.2 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 AAAP01003304.1_2 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 AAAP01003304.1_2 - 0.068 12.6 0.0 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ParA PF10609.9 AAAP01003304.1_3 - 4.9e-06 26.2 0.1 8.3e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 AAAP01003304.1_3 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01003304.1_3 - 0.0059 16.7 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AAAP01003304.1_3 - 0.008 15.7 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Response_reg PF00072.24 AAAP01003304.1_3 - 0.11 12.6 0.0 0.32 11.2 0.0 1.8 2 1 0 2 2 2 0 Response regulator receiver domain Fer4_NifH PF00142.18 AAAP01003304.1_3 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AAAP01003304.1_3 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase Pilus_CpaD PF09476.10 AAAP01003304.1_4 - 2.9e-60 203.5 0.0 3.5e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) Phage_int_SAM_1 PF02899.17 AAAP01003305.1_1 - 9.6e-18 64.3 0.0 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAAP01003305.1_1 - 6.6e-05 23.3 0.0 9.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_2 PF12834.7 AAAP01003305.1_1 - 0.00064 20.3 0.0 0.0009 19.9 0.0 1.1 1 0 0 1 1 1 1 Phage integrase, N-terminal DUF802 PF05650.11 AAAP01003305.1_1 - 0.0091 16.5 1.1 0.015 15.7 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF802) HRDC PF00570.23 AAAP01003305.1_1 - 0.063 13.3 1.1 0.16 12.0 1.1 1.7 1 0 0 1 1 1 0 HRDC domain Glyoxalase PF00903.25 AAAP01003305.1_2 - 1.2e-11 44.9 0.1 1.6e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AAAP01003305.1_2 - 1.7e-09 37.9 0.0 3e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAAP01003305.1_2 - 0.00066 19.8 0.0 0.0042 17.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AAAP01003305.1_2 - 0.0031 18.3 0.1 0.0045 17.8 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain NIPSNAP PF07978.13 AAAP01003306.1_1 - 0.061 13.6 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 NIPSNAP SEEK1 PF15357.6 AAAP01003306.1_1 - 0.17 12.0 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 SecE PF00584.20 AAAP01003306.1_2 - 0.072 13.0 3.6 0.29 11.1 2.2 2.1 1 1 1 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DAGK_prokar PF01219.19 AAAP01003306.1_4 - 1.2e-24 86.1 0.5 1.4e-24 85.9 0.5 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase PRA1 PF03208.19 AAAP01003306.1_4 - 0.86 9.2 4.5 0.37 10.4 1.7 1.7 1 1 1 2 2 2 0 PRA1 family protein DUF2892 PF11127.8 AAAP01003306.1_4 - 9.9 6.3 12.1 1.5 8.9 5.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) AbrB PF05145.12 AAAP01003306.1_5 - 8e-67 225.4 26.9 8.9e-67 225.3 26.9 1.0 1 0 0 1 1 1 1 Transition state regulatory protein AbrB ACR_tran PF00873.19 AAAP01003307.1_1 - 4.4e-151 504.7 3.8 5.3e-151 504.5 3.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003307.1_1 - 2.7e-12 46.3 10.1 2.7e-12 46.3 10.1 1.8 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 AAAP01003307.1_1 - 1.1e-06 28.2 9.0 1.1e-06 28.2 9.0 1.6 2 0 0 2 2 2 1 Protein export membrane protein DUF4149 PF13664.6 AAAP01003307.1_1 - 0.032 14.6 1.2 0.032 14.6 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Patched PF02460.18 AAAP01003307.1_1 - 0.11 10.6 9.2 0.14 10.2 9.2 1.1 1 0 0 1 1 1 0 Patched family ABC_membrane PF00664.23 AAAP01003307.1_1 - 0.42 10.2 8.0 0.081 12.6 1.9 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF5090 PF17009.5 AAAP01003307.1_1 - 0.97 9.4 3.9 2.2 8.2 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) ACR_tran PF00873.19 AAAP01003307.1_2 - 2.6e-77 260.5 0.1 3.1e-77 260.2 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Lyase_1 PF00206.20 AAAP01003308.1_1 - 2e-76 257.4 0.0 2.7e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AAAP01003308.1_1 - 7.9e-24 84.2 0.2 7.9e-24 84.2 0.2 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Redoxin PF08534.10 AAAP01003308.1_2 - 4.1e-15 55.8 0.0 6.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01003308.1_2 - 1.1e-13 51.2 0.0 1.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAAP01003308.1_2 - 2.8e-09 37.2 0.0 3.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AAAP01003308.1_2 - 3.6e-07 30.1 0.0 1.4e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin GSHPx PF00255.19 AAAP01003308.1_2 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase Thioredoxin_2 PF13098.6 AAAP01003308.1_2 - 0.09 13.2 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Na_H_antiport_1 PF06965.12 AAAP01003308.1_3 - 4e-37 127.9 2.0 5.5e-37 127.5 2.0 1.2 1 1 0 1 1 1 1 Na+/H+ antiporter 1 Na_H_Exchanger PF00999.21 AAAP01003308.1_3 - 0.00018 20.4 0.8 0.00022 20.1 0.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HTH_Crp_2 PF13545.6 AAAP01003309.1_1 - 3e-16 59.1 2.6 6.8e-16 58.0 2.1 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAAP01003309.1_1 - 5.6e-06 26.2 0.6 1.4e-05 24.9 0.6 1.7 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AAAP01003309.1_1 - 1.7e-05 25.1 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 AAAP01003309.1_1 - 6.4e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 MarR family GntR PF00392.21 AAAP01003309.1_1 - 8.1e-05 22.2 0.3 0.00028 20.5 0.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 AAAP01003309.1_1 - 0.0023 18.0 0.2 0.0061 16.6 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Crp PF00325.20 AAAP01003309.1_1 - 0.008 15.8 0.2 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family TrmB PF01978.19 AAAP01003309.1_1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AAAP01003309.1_1 - 0.059 13.6 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AAAP01003309.1_1 - 0.073 12.9 1.5 0.16 11.8 0.6 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003309.1_1 - 0.088 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain TFIIE_alpha PF02002.17 AAAP01003309.1_1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit GAF PF01590.26 AAAP01003309.1_2 - 2.5e-05 24.9 0.0 3.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAAP01003309.1_2 - 0.00056 20.2 0.3 0.046 14.0 0.0 2.2 2 0 0 2 2 2 2 GAF domain DsbD PF02683.15 AAAP01003310.1_1 - 1.9e-09 37.8 9.4 2.5e-09 37.4 9.4 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AAAP01003310.1_1 - 0.012 15.6 26.9 0.058 13.3 26.1 2.0 1 1 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region HMA PF00403.26 AAAP01003310.1_2 - 1.4e-12 47.9 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase PF00702.26 AAAP01003310.1_3 - 2.8e-34 119.3 4.4 3.5e-34 119.0 4.4 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003310.1_3 - 3.3e-09 36.8 0.5 1.6e-06 28.1 0.5 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003310.1_3 - 5.3e-07 30.2 0.7 1.7e-06 28.6 0.7 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01003310.1_3 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase UPF0225 PF17775.1 AAAP01003311.1_2 - 1.4e-29 102.8 0.0 1.6e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AAAP01003311.1_2 - 4.1e-16 58.6 26.8 2e-10 40.4 12.2 2.3 2 0 0 2 2 2 2 SEC-C motif FAD_binding_3 PF01494.19 AAAP01003311.1_3 - 2.5e-31 109.2 0.0 3.1e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DDE_Tnp_Tn3 PF01526.17 AAAP01003312.1_2 - 5.2e-30 104.5 0.0 5.7e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain DUF5480 PF17576.2 AAAP01003312.1_2 - 0.063 13.3 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5480) Peptidase_M19 PF01244.21 AAAP01003312.1_2 - 0.093 11.9 0.1 1.8 7.7 0.0 2.1 1 1 1 2 2 2 0 Membrane dipeptidase (Peptidase family M19) ATP_bind_3 PF01171.20 AAAP01003313.1_1 - 1.3e-50 171.7 0.0 1.6e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 AAAP01003313.1_1 - 0.16 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TPR_6 PF13174.6 AAAP01003313.1_2 - 9.2e-11 41.7 7.1 0.006 17.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003313.1_2 - 1.6e-10 41.4 10.0 4.4e-08 33.6 1.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.6 AAAP01003313.1_2 - 7.2e-08 32.4 1.2 0.0001 22.1 0.1 2.2 1 1 1 2 2 2 2 Outer membrane lipoprotein TolA_bind_tri PF16331.5 AAAP01003313.1_2 - 2.8e-07 30.5 0.8 5.8e-07 29.5 0.8 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_14 PF13428.6 AAAP01003313.1_2 - 0.00015 22.3 8.5 2.4 9.2 0.7 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003313.1_2 - 0.0017 18.3 2.7 0.29 11.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003313.1_2 - 0.0024 18.1 2.1 0.67 10.2 0.3 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 AAAP01003313.1_2 - 0.0031 17.8 6.9 2.6 8.4 0.4 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 AAAP01003313.1_2 - 0.0059 16.3 1.1 0.011 15.5 1.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain FlaC_arch PF05377.11 AAAP01003313.1_2 - 0.0078 16.6 0.3 0.022 15.1 0.2 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) TPR_8 PF13181.6 AAAP01003313.1_2 - 0.015 15.5 0.4 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SOGA PF11365.8 AAAP01003313.1_2 - 0.064 14.4 0.3 0.15 13.2 0.2 1.7 1 1 0 1 1 1 0 Protein SOGA TPR_18 PF13512.6 AAAP01003313.1_2 - 0.077 13.1 0.5 0.52 10.4 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat ZapB PF06005.12 AAAP01003313.1_2 - 0.15 12.5 2.2 0.32 11.5 2.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 AAAP01003313.1_2 - 0.15 12.7 0.3 0.15 12.7 0.3 2.0 2 0 0 2 2 2 0 SlyX Lebercilin PF15619.6 AAAP01003313.1_2 - 0.16 11.6 3.6 0.11 12.2 1.0 1.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TPR_19 PF14559.6 AAAP01003313.1_2 - 0.23 12.0 3.9 7.8 7.1 0.6 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003313.1_2 - 0.6 10.9 13.6 0.7 10.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Rho_Binding PF08912.11 AAAP01003313.1_2 - 0.8 10.6 2.9 1.4 9.8 0.2 2.5 3 0 0 3 3 3 0 Rho Binding OmpA PF00691.20 AAAP01003313.1_3 - 5.3e-25 87.6 0.0 6.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 OmpA family PdxA PF04166.12 AAAP01003314.1_1 - 6.2e-69 232.5 0.0 7.3e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA TOBE PF03459.17 AAAP01003314.1_2 - 5.7e-16 58.6 0.7 5.7e-16 58.6 0.7 2.0 2 0 0 2 2 2 1 TOBE domain ABC_tran PF00005.27 AAAP01003314.1_2 - 5.3e-07 30.2 0.1 8.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter CHS5_N PF16892.5 AAAP01003314.1_2 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus SbcCD_C PF13558.6 AAAP01003314.1_2 - 0.16 12.2 0.1 0.73 10.1 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AAAP01003314.1_2 - 0.2 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Glyco_hydro_8 PF01270.17 AAAP01003315.1_1 - 1.1e-60 205.3 0.0 1.7e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 Guanylate_cyc PF00211.20 AAAP01003316.1_1 - 1.6e-15 57.2 0.2 9.9e-15 54.6 0.1 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 AAAP01003316.1_2 - 4.3e-22 78.6 0.0 5.8e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fer2 PF00111.27 AAAP01003316.1_2 - 3.1e-10 39.9 0.5 9.1e-10 38.4 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PAP2_3 PF14378.6 AAAP01003317.1_1 - 1.3e-41 142.4 16.8 1.3e-41 142.4 16.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 AAAP01003317.1_1 - 0.065 13.8 0.4 0.065 13.8 0.4 2.8 3 1 0 3 3 3 0 PAP2 superfamily C-terminal FAD_binding_3 PF01494.19 AAAP01003317.1_2 - 1.2e-09 37.9 0.7 1.5e-09 37.6 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain AcylCoA_dehyd_C PF12186.8 AAAP01003317.1_2 - 0.2 11.8 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal ABC_tran PF00005.27 AAAP01003318.1_1 - 7.6e-31 107.5 0.0 1.4e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAAP01003318.1_1 - 6.8e-12 45.6 6.6 1.1e-11 44.9 6.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AAAP01003318.1_1 - 3.3e-05 23.4 0.0 6.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAAP01003318.1_1 - 0.0045 17.1 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AAAP01003318.1_1 - 0.019 15.4 0.8 0.05 14.0 0.8 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAAP01003318.1_1 - 0.063 13.0 0.8 0.16 11.7 0.8 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003318.1_1 - 0.079 13.1 0.2 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAAP01003318.1_1 - 0.082 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAAP01003318.1_1 - 0.1 12.4 0.1 0.56 10.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003318.1_1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF1129 PF06570.11 AAAP01003318.1_1 - 1 8.8 12.3 3.7 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) SpoU_methylase PF00588.19 AAAP01003318.1_2 - 9.1e-21 74.5 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family GGDEF PF00990.21 AAAP01003319.1_1 - 3.3e-57 192.8 0.1 5.5e-57 192.0 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain EAL PF00563.20 AAAP01003319.1_1 - 8.4e-23 81.1 0.0 1.6e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 EAL domain PAS_9 PF13426.7 AAAP01003319.1_1 - 6.8e-19 68.0 0.1 1.7e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003319.1_1 - 4.5e-13 49.2 0.0 1.2e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold CBS PF00571.28 AAAP01003319.1_1 - 7.3e-13 48.8 1.0 5e-09 36.5 0.0 3.4 3 0 0 3 3 3 2 CBS domain PAS_4 PF08448.10 AAAP01003319.1_1 - 7.1e-12 45.6 0.0 2.4e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAAP01003319.1_1 - 1.6e-10 41.1 0.1 5.9e-10 39.3 0.3 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003319.1_1 - 1.7e-10 40.6 0.1 1e-09 38.2 0.0 2.4 2 1 1 3 3 3 1 PAS domain PAS_7 PF12860.7 AAAP01003319.1_1 - 0.0029 17.8 0.1 0.29 11.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_12 PF18095.1 AAAP01003319.1_1 - 0.046 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Inositol_P PF00459.25 AAAP01003320.1_1 - 4.2e-16 59.3 0.0 4.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family CSD PF00313.22 AAAP01003320.1_3 - 2.1e-24 85.1 0.2 2.2e-24 85.0 0.2 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01003320.1_3 - 5.8e-05 22.7 0.2 7.2e-05 22.4 0.2 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 AAAP01003320.1_3 - 0.0024 17.7 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain Pyr_redox_2 PF07992.14 AAAP01003321.1_1 - 8.4e-05 21.9 0.0 0.0018 17.6 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01003321.1_1 - 8.6e-05 21.9 0.0 0.00044 19.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003321.1_1 - 0.0012 19.0 0.1 0.021 15.1 0.0 2.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAS PF03059.16 AAAP01003321.1_1 - 0.011 15.2 0.0 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Nicotianamine synthase protein HI0933_like PF03486.14 AAAP01003321.1_1 - 0.014 14.1 0.0 0.13 10.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 AAAP01003321.1_1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 1 0 1 1 1 0 Lycopene cyclase protein AMP-binding PF00501.28 AAAP01003321.1_2 - 1.5e-83 280.8 0.0 1.8e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003321.1_2 - 5.8e-15 56.0 1.5 1e-14 55.2 0.7 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Amidase PF01425.21 AAAP01003322.1_2 - 8.3e-70 236.0 3.1 1.1e-69 235.6 3.1 1.1 1 0 0 1 1 1 1 Amidase GSCFA PF08885.11 AAAP01003323.1_1 - 6.4e-51 173.3 0.0 7.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 GSCFA family Porphobil_deamC PF03900.15 AAAP01003323.1_2 - 1.2e-14 54.4 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Porphobil_deam PF01379.20 AAAP01003323.1_2 - 0.0018 17.8 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Acyl-CoA_dh_1 PF00441.24 AAAP01003324.1_1 - 5.2e-42 143.6 5.6 6.5e-42 143.3 5.6 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01003324.1_1 - 5e-15 56.0 2.3 6.2e-15 55.7 2.3 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAS_8 PF13188.7 AAAP01003324.1_2 - 8.4e-05 22.5 0.1 0.48 10.5 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AAAP01003324.1_2 - 0.00083 19.6 0.5 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold MCPsignal PF00015.21 AAAP01003325.1_1 - 7.7e-18 64.9 28.8 2.6e-17 63.2 12.0 3.0 2 1 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003325.1_1 - 1.7e-11 44.3 1.4 1.5e-10 41.3 0.0 3.2 2 1 0 2 2 2 1 HAMP domain DUF948 PF06103.11 AAAP01003325.1_1 - 0.24 11.7 8.8 0.66 10.3 2.0 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003325.1_1 - 2.7 8.0 5.7 19 5.3 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PilJ PF13675.6 AAAP01003325.1_2 - 7.1e-08 32.5 1.4 8.7e-08 32.2 1.4 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term EptA_B_N PF08019.12 AAAP01003325.1_2 - 0.073 12.9 0.2 1.6 8.6 0.0 2.0 1 1 1 2 2 2 0 Phosphoethanolamine transferase EptA/EptB CheW PF01584.19 AAAP01003325.1_3 - 2.4e-11 43.4 0.0 2.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain 2-Hacid_dh_C PF02826.19 AAAP01003326.1_1 - 1.4e-53 180.9 0.0 2.1e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01003326.1_1 - 2.7e-35 121.0 0.1 4.7e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 AAAP01003326.1_1 - 3.4e-10 39.5 0.1 1.7e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 ACT domain IlvN PF07991.12 AAAP01003326.1_1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 AAAP01003326.1_1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01003326.1_1 - 0.039 14.5 0.3 0.14 12.7 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AAAP01003326.1_1 - 0.04 14.0 0.1 0.074 13.1 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BAT PF15915.5 AAAP01003326.1_1 - 0.055 13.3 0.3 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 GAF and HTH_10 associated domain UPF0020 PF01170.18 AAAP01003326.1_1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PEP-utilizers_C PF02896.18 AAAP01003327.1_1 - 2.3e-88 296.1 0.0 3.2e-88 295.7 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AAAP01003327.1_1 - 4.2e-40 138.0 0.3 1.5e-38 132.9 0.3 2.3 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AAAP01003327.1_1 - 4.3e-29 100.0 2.6 1.2e-28 98.6 2.6 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PEP-utilisers_N PF05524.13 AAAP01003327.1_1 - 1.7 8.9 5.3 5 7.3 0.1 3.9 4 0 0 4 4 4 0 PEP-utilising enzyme, N-terminal CLP_protease PF00574.23 AAAP01003328.1_2 - 6.7e-74 247.7 0.0 7.7e-74 247.5 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF2742 PF10888.8 AAAP01003328.1_3 - 0.13 12.5 0.7 0.88 9.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2742) HTH_31 PF13560.6 AAAP01003328.1_4 - 1e-10 41.8 6.8 2.3e-10 40.7 6.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003328.1_4 - 5.1e-10 39.3 0.1 7.6e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 AAAP01003328.1_4 - 1.1e-05 25.2 0.2 2e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003328.1_4 - 0.0011 19.0 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003328.1_4 - 0.06 13.8 0.0 0.095 13.1 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TENA_THI-4 PF03070.16 AAAP01003328.1_5 - 0.0093 15.8 0.1 0.0094 15.8 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family tRNA-synt_1_2 PF13603.6 AAAP01003329.1_2 - 8.6e-64 214.5 0.0 1.2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 AAAP01003329.1_2 - 1.1e-27 96.6 0.0 1.5e-11 43.3 0.0 3.7 2 1 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01003329.1_2 - 2.7e-05 23.1 0.2 0.39 9.4 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Zn-ribbon_8 PF09723.10 AAAP01003329.1_2 - 9.7 6.4 6.0 2.6 8.3 0.3 2.6 3 0 0 3 3 3 0 Zinc ribbon domain ACR_tran PF00873.19 AAAP01003330.1_1 - 1.2e-61 208.6 12.6 1.5e-61 208.4 12.6 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003330.1_1 - 0.00025 20.1 13.8 0.00033 19.7 13.8 1.0 1 0 0 1 1 1 1 MMPL family SecD_SecF PF02355.16 AAAP01003330.1_1 - 0.00069 19.0 6.2 0.00096 18.6 6.2 1.2 1 0 0 1 1 1 1 Protein export membrane protein NICE-3 PF07406.11 AAAP01003330.1_2 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 NICE-3 protein ZapB PF06005.12 AAAP01003330.1_3 - 0.00047 20.5 2.0 0.00076 19.9 2.0 1.4 1 0 0 1 1 1 1 Cell division protein ZapB APG6_N PF17675.1 AAAP01003330.1_3 - 0.017 15.7 4.7 0.021 15.3 4.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 AAAP01003330.1_3 - 0.022 15.7 2.7 0.023 15.6 2.0 1.4 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 AAAP01003330.1_3 - 0.19 12.4 0.1 0.23 12.1 0.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 AAAP01003330.1_3 - 0.2 11.4 6.5 0.17 11.7 5.2 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF1178 PF06676.11 AAAP01003330.1_3 - 0.28 11.6 4.6 0.36 11.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) PV-1 PF06637.11 AAAP01003330.1_3 - 0.79 8.5 10.0 0.95 8.2 10.0 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Atg14 PF10186.9 AAAP01003330.1_3 - 1.5 7.9 3.6 1.7 7.6 3.6 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 AAAP01003330.1_3 - 5.4 7.5 13.1 22 5.6 12.1 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) zf-dskA_traR PF01258.17 AAAP01003330.1_5 - 0.19 11.7 4.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger PAS_3 PF08447.12 AAAP01003331.1_1 - 4e-45 152.0 0.0 2.1e-14 53.6 0.0 3.2 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AAAP01003331.1_1 - 3.3e-44 149.6 3.0 8.5e-16 58.2 0.0 3.3 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01003331.1_1 - 4.1e-37 126.6 0.0 2.4e-11 43.8 0.0 3.1 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AAAP01003331.1_1 - 1.5e-31 108.7 0.0 1.5e-09 37.8 0.0 3.2 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AAAP01003331.1_1 - 8.6e-10 38.4 0.2 0.19 11.8 0.0 3.7 4 0 0 4 4 4 3 PAS domain Acid_phosphat_B PF03767.14 AAAP01003331.1_1 - 6.2e-05 22.7 0.0 0.081 12.5 0.0 3.1 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.7 AAAP01003331.1_1 - 0.028 14.8 0.4 2.8 8.3 0.0 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase sCache_3_3 PF17202.4 AAAP01003331.1_1 - 0.041 14.3 0.0 71 3.9 0.0 3.4 3 0 0 3 3 3 0 Single cache domain 3 GARS_C PF02843.16 AAAP01003331.1_1 - 0.49 10.7 4.0 7.6 6.9 0.0 3.4 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain SIMPL PF04402.14 AAAP01003331.1_2 - 5.8e-24 85.7 0.2 7.2e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) RICH PF05062.12 AAAP01003331.1_2 - 0.15 12.4 0.9 0.19 12.1 0.1 1.5 2 0 0 2 2 2 0 RICH domain AnmK PF03702.14 AAAP01003332.1_1 - 1e-78 265.0 0.3 1.3e-78 264.7 0.3 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase DUF3578 PF12102.8 AAAP01003332.1_2 - 1.4e-45 155.1 0.0 1.6e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3578) HTH_29 PF13551.6 AAAP01003332.1_2 - 0.059 13.4 0.1 13 5.9 0.2 2.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_3 PF01381.22 AAAP01003332.1_3 - 1.7e-08 34.4 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_7 PF02796.15 AAAP01003332.1_3 - 0.00053 20.0 0.0 0.0012 18.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_Tnp_1_assoc PF13808.6 AAAP01003332.1_3 - 0.00098 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 DDE_Tnp_1-associated HTH_26 PF13443.6 AAAP01003332.1_3 - 0.0039 17.6 0.0 0.0055 17.1 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TetR_N PF00440.23 AAAP01003332.1_3 - 0.01 15.6 1.0 0.019 14.7 0.2 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_29 PF13551.6 AAAP01003332.1_3 - 0.035 14.1 0.4 0.059 13.4 0.4 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 AAAP01003332.1_3 - 0.045 13.6 2.2 0.25 11.2 0.4 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 AAAP01003332.1_3 - 0.049 13.8 0.4 0.086 13.0 0.4 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01003332.1_3 - 0.075 13.0 0.2 0.14 12.2 0.2 1.6 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain LacI PF00356.21 AAAP01003332.1_3 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_AraC PF00165.23 AAAP01003332.1_3 - 0.15 12.2 0.0 1 9.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Gp49 PF05973.14 AAAP01003332.1_4 - 8.4e-09 35.5 0.0 1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) Chorismate_synt PF01264.21 AAAP01003332.1_5 - 1.5e-06 27.2 0.2 1.6e-06 27.1 0.2 1.0 1 0 0 1 1 1 1 Chorismate synthase Sulf_transp PF04143.14 AAAP01003333.1_1 - 0.0016 18.1 8.1 0.0028 17.3 8.1 1.4 1 1 0 1 1 1 1 Sulphur transport FA_desaturase PF00487.24 AAAP01003333.1_1 - 0.1 12.4 2.3 0.12 12.2 2.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF4229 PF14012.6 AAAP01003333.1_1 - 4.2 7.5 11.4 2.3 8.4 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Metal_resist PF13801.6 AAAP01003333.1_5 - 0.43 10.8 6.7 0.98 9.6 6.7 1.7 1 1 0 1 1 1 0 Heavy-metal resistance EAL PF00563.20 AAAP01003334.1_2 - 1.6e-56 191.5 0.0 2.2e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003334.1_2 - 1e-28 100.1 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain AAA_34 PF13872.6 AAAP01003335.1_1 - 4.6e-119 396.8 0.0 5.7e-119 396.5 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ResIII PF04851.15 AAAP01003335.1_1 - 6e-05 23.1 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Transgly PF00912.22 AAAP01003336.1_1 - 2.5e-59 199.7 0.1 3.4e-59 199.3 0.1 1.2 1 0 0 1 1 1 1 Transglycosylase Amidase_3 PF01520.18 AAAP01003336.1_2 - 1.2e-43 149.3 0.0 3.1e-43 147.9 0.0 1.6 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AAAP01003336.1_2 - 2.6e-12 46.7 0.0 1.3e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 AMIN domain Rrn6 PF10214.9 AAAP01003336.1_4 - 1.1 7.6 3.1 1.2 7.6 3.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mur_ligase_C PF02875.21 AAAP01003337.1_1 - 9.8e-12 45.0 0.0 3.8e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Toprim_3 PF13362.6 AAAP01003337.1_1 - 0.025 14.9 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Glycos_transf_4 PF00953.21 AAAP01003337.1_3 - 6.5e-28 97.7 13.9 6.5e-28 97.7 13.9 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 4 Mur_ligase_M PF08245.12 AAAP01003337.1_4 - 1.4e-29 103.4 0.0 1.9e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain 2-Hacid_dh_C PF02826.19 AAAP01003337.1_4 - 0.00049 19.5 0.0 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAAP01003337.1_4 - 0.017 14.7 0.0 0.071 12.7 0.0 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ketoacyl-synt PF00109.26 AAAP01003338.1_1 - 5.5e-50 170.3 0.3 5.5e-50 170.3 0.3 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAAP01003338.1_1 - 2.8e-35 120.9 1.6 5e-35 120.1 1.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AAAP01003338.1_1 - 6.9e-06 25.6 0.6 6.9e-05 22.3 0.2 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAAP01003338.1_1 - 0.0027 17.3 4.9 0.007 16.0 0.2 3.1 2 1 1 3 3 3 1 Thiolase, C-terminal domain Glyoxalase PF00903.25 AAAP01003339.1_2 - 0.00019 21.6 0.1 0.00032 20.9 0.1 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01003339.1_2 - 0.00093 20.0 0.5 0.0017 19.1 0.5 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAAP01003339.1_2 - 0.019 15.2 0.2 2.7 8.3 0.0 2.1 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAAP01003339.1_2 - 0.067 13.3 0.1 13 5.9 0.0 2.1 1 1 1 2 2 2 0 Glyoxalase-like domain Acetyltransf_10 PF13673.7 AAAP01003339.1_3 - 2.8e-16 59.6 0.0 3.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01003339.1_3 - 8.4e-13 48.6 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003339.1_3 - 2.7e-10 40.5 0.0 3.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 AAAP01003339.1_3 - 2.2e-05 24.6 2.5 3.9e-05 23.8 2.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003339.1_3 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AAAP01003339.1_3 - 0.018 15.7 0.0 0.053 14.2 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAAP01003339.1_3 - 0.063 13.4 0.1 0.49 10.5 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01003339.1_3 - 0.14 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SBF PF01758.16 AAAP01003339.1_4 - 2.5e-57 193.7 5.1 2.5e-57 193.7 5.1 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family Kinocilin PF15033.6 AAAP01003339.1_4 - 0.0033 17.1 0.9 0.0087 15.7 0.9 1.7 1 0 0 1 1 1 1 Kinocilin protein HTH_5 PF01022.20 AAAP01003339.1_5 - 1.8e-15 56.5 0.1 2.8e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01003339.1_5 - 4.9e-12 45.7 0.4 6.9e-12 45.3 0.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003339.1_5 - 0.02 14.4 0.0 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAAP01003339.1_5 - 0.035 13.9 0.2 0.085 12.7 0.1 1.8 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01003339.1_5 - 0.047 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAAP01003339.1_5 - 0.07 13.5 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator RepL PF05732.11 AAAP01003339.1_5 - 0.17 11.3 0.0 0.97 8.8 0.0 1.9 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) AlaDh_PNT_C PF01262.21 AAAP01003340.1_1 - 1.7e-13 50.4 0.0 1.8e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 AAAP01003340.1_2 - 2.3e-36 124.1 6.2 3.7e-36 123.4 6.2 1.3 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF3392 PF11872.8 AAAP01003340.1_2 - 2.2e-05 24.7 0.9 3.5e-05 24.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) PspC PF04024.12 AAAP01003340.1_2 - 0.0011 18.7 0.7 0.0026 17.5 0.7 1.5 1 0 0 1 1 1 1 PspC domain DUF2206 PF09971.9 AAAP01003340.1_2 - 0.0034 16.2 1.9 0.0037 16.1 1.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) Alanine_zipper PF11839.8 AAAP01003340.1_2 - 0.54 10.7 17.3 0.75 10.2 17.3 1.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein PNTB PF02233.16 AAAP01003340.1_3 - 0.00073 18.6 0.0 0.00073 18.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit PNTB PF02233.16 AAAP01003340.1_4 - 1.2e-172 575.0 16.5 1.4e-172 574.8 16.5 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AAAP01003340.1_4 - 0.00042 20.1 0.1 0.003 17.3 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Asn_synthase PF00733.21 AAAP01003340.1_4 - 0.035 13.8 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase HMD PF03201.16 AAAP01003340.1_4 - 0.13 12.5 0.4 1.4 9.2 0.0 2.6 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DHH PF01368.20 AAAP01003340.1_5 - 1.6e-08 34.7 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 DHH family Peripla_BP_6 PF13458.6 AAAP01003340.1_5 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein PALP PF00291.25 AAAP01003340.1_5 - 0.005 16.3 0.1 0.44 9.9 0.0 2.2 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme DUF218 PF02698.17 AAAP01003340.1_5 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain ParBc PF02195.18 AAAP01003341.1_1 - 1e-26 93.0 0.3 1.4e-26 92.6 0.3 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 AAAP01003341.1_2 - 1.3e-16 60.1 0.2 2.2e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 HTH domain found in ParB protein KorB PF08535.10 AAAP01003341.1_2 - 0.0042 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 KorB domain HTH_3 PF01381.22 AAAP01003341.1_2 - 0.0054 16.8 0.1 0.064 13.3 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix HTH_Crp_2 PF13545.6 AAAP01003341.1_2 - 0.0073 16.3 0.2 0.017 15.1 0.2 1.8 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 AAAP01003341.1_2 - 0.019 15.0 0.6 5.5 7.1 0.0 2.7 2 1 0 2 2 2 0 Winged helix-turn helix HTH_17 PF12728.7 AAAP01003341.1_2 - 0.047 13.9 0.1 0.83 9.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01003341.1_2 - 0.059 13.1 0.1 3.9 7.3 0.0 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain DNA_pol3_delta PF06144.13 AAAP01003341.1_3 - 1.8e-07 31.1 0.0 6.5e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delt_C PF14840.6 AAAP01003341.1_3 - 7.9e-05 23.0 0.1 0.00015 22.1 0.1 1.4 1 0 0 1 1 1 1 Processivity clamp loader gamma complex DNA pol III C-term LptE PF04390.12 AAAP01003341.1_4 - 1.8e-09 38.3 1.9 2.2e-09 37.9 1.9 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly BKACE PF05853.12 AAAP01003342.1_1 - 2.9e-16 59.6 0.9 3e-16 59.6 0.9 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme DUF308 PF03729.13 AAAP01003342.1_2 - 8.6e-28 96.5 43.8 3.7e-12 46.4 9.5 3.2 1 1 2 3 3 3 3 Short repeat of unknown function (DUF308) DUF442 PF04273.13 AAAP01003342.1_3 - 2.3e-39 133.9 0.1 4.8e-39 132.8 0.1 1.5 1 1 1 2 2 2 1 Putative phosphatase (DUF442) NTP_transf_3 PF12804.7 AAAP01003342.1_3 - 0.00062 20.2 1.5 0.00098 19.5 1.0 1.4 1 1 1 2 2 2 1 MobA-like NTP transferase domain GGDEF_2 PF17853.1 AAAP01003342.1_3 - 0.069 13.4 0.5 0.72 10.1 0.0 2.3 2 1 0 2 2 2 0 GGDEF-like domain HNH PF01844.23 AAAP01003342.1_4 - 0.0022 18.1 0.8 0.0093 16.1 0.8 1.9 1 1 0 1 1 1 1 HNH endonuclease Rad50_zn_hook PF04423.14 AAAP01003342.1_4 - 0.0065 16.3 0.2 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 Rad50 zinc hook motif HMA PF00403.26 AAAP01003343.1_1 - 4.5e-11 43.0 0.0 6.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF3040 PF11239.8 AAAP01003343.1_1 - 0.15 12.4 9.6 0.59 10.4 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF3382 PF11862.8 AAAP01003343.1_1 - 4 7.8 11.1 1.4 9.3 6.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) HMA PF00403.26 AAAP01003343.1_2 - 5e-09 36.5 0.0 5.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain MerR-DNA-bind PF09278.11 AAAP01003343.1_3 - 1e-19 70.8 7.0 1e-19 70.8 7.0 1.5 2 0 0 2 2 2 1 MerR, DNA binding MerR_1 PF13411.6 AAAP01003343.1_3 - 7.8e-17 61.1 0.0 1.5e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003343.1_3 - 1.5e-11 43.9 1.1 2.5e-11 43.2 0.4 1.8 2 0 0 2 2 2 1 MerR family regulatory protein DUF3348 PF11828.8 AAAP01003343.1_3 - 0.041 13.6 0.4 0.047 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) UDG PF03167.19 AAAP01003344.1_1 - 3.4e-38 131.1 0.0 3.8e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zn_peptidase PF04228.13 AAAP01003344.1_2 - 4.6e-115 384.1 1.7 5.1e-115 383.9 1.7 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Reprolysin_3 PF13582.6 AAAP01003344.1_2 - 0.02 15.4 0.1 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF2623 PF11115.8 AAAP01003344.1_2 - 0.034 14.2 0.0 0.82 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) Hexapep PF00132.24 AAAP01003344.1_3 - 2.8e-11 42.7 3.5 2.8e-11 42.7 3.5 1.9 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003344.1_3 - 2.6e-10 39.9 4.1 2.6e-10 39.9 4.1 1.4 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DNA_topoisoIV PF00521.20 AAAP01003345.1_1 - 2.4e-34 119.0 0.0 3.2e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A RecO_C PF02565.15 AAAP01003345.1_2 - 8.4e-19 67.9 0.0 9.9e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Recombination protein O C terminal FliH PF02108.16 AAAP01003346.1_1 - 3.4e-05 23.9 0.1 4.6e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH FliG_C PF01706.16 AAAP01003346.1_2 - 3e-38 130.3 7.5 4.7e-35 120.1 1.4 2.7 2 1 0 2 2 2 2 FliG C-terminal domain FliG_N PF14842.6 AAAP01003346.1_2 - 1e-28 99.9 7.6 2.1e-20 73.2 0.0 3.6 3 1 0 3 3 3 3 FliG N-terminal domain FliG_M PF14841.6 AAAP01003346.1_2 - 1.6e-26 92.3 6.0 1.8e-23 82.6 1.2 3.6 4 0 0 4 4 4 2 FliG middle domain MgtE_N PF03448.17 AAAP01003346.1_2 - 7.6e-09 36.1 10.6 0.00072 20.1 1.8 4.8 3 1 2 5 5 5 3 MgtE intracellular N domain TFA2_Winged_2 PF18121.1 AAAP01003346.1_2 - 0.057 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Y1_Tnp PF01797.16 AAAP01003346.1_2 - 0.18 11.9 0.1 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Transposase IS200 like RisS_PPD PF16524.5 AAAP01003346.1_2 - 0.29 11.4 1.8 26 5.1 0.2 3.5 3 1 0 3 3 3 0 Periplasmic domain of Sensor histidine kinase RisS YscJ_FliF_C PF08345.11 AAAP01003346.1_3 - 8.8e-38 130.0 3.3 8.8e-38 130.0 3.3 1.5 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal adh_short PF00106.25 AAAP01003347.1_1 - 3.1e-27 95.3 0.6 3.4e-27 95.2 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003347.1_1 - 6.5e-21 74.9 1.0 7.6e-21 74.7 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003347.1_1 - 8.4e-10 38.8 1.2 1.2e-09 38.4 1.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003347.1_1 - 0.00053 19.9 1.1 0.00078 19.4 1.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAAP01003347.1_1 - 0.00058 19.4 0.1 0.00061 19.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AAAP01003347.1_1 - 0.0031 18.1 2.3 0.008 16.7 1.7 1.8 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 AAAP01003347.1_1 - 0.032 14.5 0.2 0.048 13.9 0.2 1.3 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 AAAP01003347.1_1 - 0.06 13.8 0.1 0.084 13.3 0.1 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 AAAP01003347.1_1 - 0.062 13.4 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_114 PF03537.13 AAAP01003347.1_1 - 0.093 12.0 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Acyl-CoA_dh_1 PF00441.24 AAAP01003347.1_2 - 4.6e-46 156.7 5.2 5.7e-46 156.4 5.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01003347.1_2 - 6.7e-22 78.2 5.6 8.1e-22 77.9 5.6 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_2 PF00891.18 AAAP01003348.1_2 - 9.9e-23 80.5 0.0 1.3e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003348.1_2 - 5.7e-06 26.9 0.0 2.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003348.1_2 - 1.1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003348.1_2 - 0.00017 22.2 0.0 0.00032 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003348.1_2 - 0.0067 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AAAP01003348.1_2 - 0.0069 16.2 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 AAAP01003348.1_2 - 0.12 12.1 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Sterol_MT_C PF08498.10 AAAP01003348.1_2 - 0.14 12.5 0.0 3.7 7.9 0.0 2.6 3 0 0 3 3 3 0 Sterol methyltransferase C-terminal AAA_18 PF13238.6 AAAP01003348.1_3 - 4.8e-07 30.4 0.0 1.3e-06 29.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003348.1_3 - 2.7e-06 27.6 0.0 4.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003348.1_3 - 0.00014 22.3 0.0 0.00022 21.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAAP01003348.1_3 - 0.0002 21.6 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003348.1_3 - 0.00049 20.5 0.1 0.00081 19.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003348.1_3 - 0.00065 20.0 0.0 0.0011 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAAP01003348.1_3 - 0.0017 18.8 0.0 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AAAP01003348.1_3 - 0.0025 17.1 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 AAAP01003348.1_3 - 0.0033 17.4 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.18 AAAP01003348.1_3 - 0.0072 16.1 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 AAAP01003348.1_3 - 0.0074 16.0 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA_25 PF13481.6 AAAP01003348.1_3 - 0.02 14.5 0.3 0.09 12.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AAAP01003348.1_3 - 0.035 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 AAAP01003348.1_3 - 0.046 13.9 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase NACHT PF05729.12 AAAP01003348.1_3 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AAAP01003348.1_3 - 0.05 13.3 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 AAAP01003348.1_3 - 0.051 13.3 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 AAAP01003348.1_3 - 0.066 13.1 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 AAAP01003348.1_3 - 0.077 13.5 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 AAAP01003348.1_3 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 AAAP01003348.1_3 - 0.097 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 AAAP01003348.1_3 - 0.1 12.4 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 AAAP01003348.1_3 - 0.1 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 AAAP01003348.1_3 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 AAAP01003348.1_3 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01003348.1_3 - 0.22 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AAAP01003348.1_3 - 0.23 11.6 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 AAAP01003348.1_3 - 0.24 11.1 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T4SS-DNA_transf PF02534.14 AAAP01003349.1_1 - 3.2e-38 131.7 0.0 3.4e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AAAP01003349.1_1 - 5.7e-19 68.3 0.0 8.2e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AAAP01003349.1_1 - 3.6e-14 52.5 0.0 4.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 AAAP01003349.1_2 - 5.6e-19 68.3 0.0 7.6e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF3363 PF11843.8 AAAP01003349.1_3 - 1.5e-32 113.0 0.1 1.6e-32 112.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3363) Phage-tail_3 PF13550.6 AAAP01003350.1_1 - 0.0061 16.4 0.3 0.0075 16.1 0.3 1.0 1 0 0 1 1 1 1 Putative phage tail protein Fer2_4 PF13510.6 AAAP01003350.1_1 - 0.066 13.3 0.0 0.082 13.0 0.0 1.4 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain EAL PF00563.20 AAAP01003350.1_3 - 2.7e-47 161.3 0.0 4.3e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003350.1_3 - 4.6e-35 120.8 0.0 7.2e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAAP01003350.1_3 - 1.6e-13 50.7 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003350.1_3 - 2.9e-07 30.7 0.1 1.2e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAAP01003350.1_3 - 0.00018 21.5 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003350.1_3 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain DUF842 PF05811.13 AAAP01003350.1_3 - 0.22 11.2 0.2 0.48 10.1 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Glycos_transf_2 PF00535.26 AAAP01003351.1_1 - 4.4e-06 26.6 0.0 5.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003351.1_1 - 0.0024 17.8 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003351.1_1 - 0.037 14.5 0.0 0.068 13.7 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF892 PF05974.12 AAAP01003351.1_2 - 1.1e-19 71.0 0.0 1.3e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) AI-2E_transport PF01594.16 AAAP01003351.1_3 - 8.9e-28 97.4 20.4 1.3e-27 96.9 20.4 1.1 1 0 0 1 1 1 1 AI-2E family transporter Proton_antipo_M PF00361.20 AAAP01003352.1_1 - 8.6e-08 31.7 4.8 1.8e-07 30.7 4.8 1.6 1 0 0 1 1 1 1 Proton-conducting membrane transporter PriCT_2 PF08707.11 AAAP01003352.1_1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Patatin PF01734.22 AAAP01003352.1_2 - 5e-22 79.1 1.0 2.5e-21 76.8 1.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Acyl_transf_1 PF00698.21 AAAP01003352.1_2 - 0.012 15.1 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase domain bMG10 PF17973.1 AAAP01003353.1_1 - 1.1e-26 93.5 0.0 2.1e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain TED_complement PF07678.14 AAAP01003353.1_1 - 4.3e-05 22.7 0.0 7.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain Transgly PF00912.22 AAAP01003353.1_2 - 6.2e-38 130.0 0.0 8e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SSF PF00474.17 AAAP01003354.1_1 - 1.8e-26 93.0 8.7 2.8e-26 92.3 8.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3021 PF11457.8 AAAP01003354.1_1 - 3.5 8.0 17.0 7 7.0 13.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) BacA PF02673.18 AAAP01003354.1_2 - 9.9e-45 153.2 8.4 1.1e-44 153.1 8.4 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA ACT_7 PF13840.6 AAAP01003354.1_2 - 0.082 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 ACT domain YIEGIA PF14045.6 AAAP01003354.1_2 - 0.13 11.1 0.9 0.6 8.9 0.1 2.0 2 0 0 2 2 2 0 YIEGIA protein GntR PF00392.21 AAAP01003355.1_1 - 3.8e-20 71.3 0.1 6.6e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAAP01003355.1_1 - 3.5e-16 59.8 2.8 5.6e-16 59.1 2.8 1.3 1 0 0 1 1 1 1 FCD domain HTH_11 PF08279.12 AAAP01003355.1_1 - 0.00046 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AAAP01003355.1_1 - 0.0012 18.8 0.4 0.0028 17.6 0.1 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAAP01003355.1_1 - 0.0024 18.2 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 AAAP01003355.1_1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 AAAP01003355.1_1 - 0.02 15.1 0.2 0.049 13.8 0.2 1.6 1 0 0 1 1 1 0 PaaX-like protein Fe_dep_repress PF01325.19 AAAP01003355.1_1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_DeoR PF08220.12 AAAP01003355.1_1 - 0.057 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 AAAP01003355.1_1 - 0.081 12.9 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Peripla_BP_6 PF13458.6 AAAP01003355.1_2 - 3.6e-59 201.1 0.2 4.2e-59 200.9 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003355.1_2 - 6e-20 71.5 0.0 1.8e-16 60.1 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003355.1_2 - 6.2e-14 51.9 0.0 8.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region AMP-binding PF00501.28 AAAP01003355.1_3 - 4.8e-81 272.5 0.0 6e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme FlgI PF02119.16 AAAP01003356.1_1 - 1.3e-136 455.1 7.4 1.6e-136 454.8 7.4 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein Rod-binding PF10135.9 AAAP01003356.1_2 - 5.9e-08 33.2 0.1 3.2e-07 30.8 0.0 2.2 1 1 1 2 2 2 1 Rod binding protein Exo_endo_phos PF03372.23 AAAP01003357.1_1 - 0.00056 19.5 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SIS PF01380.22 AAAP01003357.1_2 - 2.4e-10 40.4 0.8 2.4e-08 33.9 0.0 3.2 3 1 1 4 4 4 1 SIS domain SIS_2 PF13580.6 AAAP01003357.1_2 - 6.6e-07 29.4 1.1 2.7e-06 27.4 1.1 1.9 1 1 0 1 1 1 1 SIS domain UBA_4 PF14555.6 AAAP01003357.1_2 - 0.0017 18.2 0.4 0.66 9.8 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain Peptidase_M24 PF00557.24 AAAP01003357.1_2 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 SIS PF01380.22 AAAP01003357.1_4 - 1.6e-19 70.1 0.1 1.5e-10 41.0 0.2 2.1 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 AAAP01003357.1_4 - 0.028 14.4 1.2 0.25 11.4 0.2 2.7 2 1 1 3 3 3 0 SIS domain TonB_dep_Rec PF00593.24 AAAP01003358.1_1 - 3.5e-44 152.5 43.2 1.8e-43 150.1 43.2 1.9 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAAP01003358.1_1 - 0.00026 21.5 0.3 0.00065 20.2 0.3 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain CoA_transf_3 PF02515.17 AAAP01003359.1_2 - 8.2e-135 449.6 0.6 9.3e-135 449.5 0.6 1.0 1 0 0 1 1 1 1 CoA-transferase family III ECH_2 PF16113.5 AAAP01003359.1_3 - 1.3e-15 57.8 0.0 1.5e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAAP01003359.1_3 - 4.8e-14 52.3 0.0 6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GCS2 PF04107.13 AAAP01003360.1_2 - 8.4e-51 173.0 0.4 1.2e-50 172.6 0.4 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) DUF4142 PF13628.6 AAAP01003360.1_3 - 1.2e-41 142.2 9.5 1.4e-41 142.0 9.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) DUF305 PF03713.13 AAAP01003360.1_3 - 0.00096 19.3 1.8 0.051 13.7 1.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF305) DUF1957 PF09210.11 AAAP01003360.1_3 - 0.0037 17.6 0.7 0.012 16.0 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1957) DUF2383 PF09537.10 AAAP01003360.1_3 - 0.054 13.8 0.3 2 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Beta_elim_lyase PF01212.21 AAAP01003360.1_4 - 1e-32 113.6 0.2 1.2e-32 113.4 0.2 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase AA_permease_2 PF13520.6 AAAP01003361.1_1 - 1e-13 51.0 13.2 1.1e-13 50.8 13.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01003361.1_1 - 1.8e-09 36.8 13.6 2.2e-09 36.4 13.6 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 AAAP01003361.1_1 - 0.46 9.5 8.8 0.57 9.2 8.8 1.0 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family TENA_THI-4 PF03070.16 AAAP01003361.1_2 - 2.5e-34 118.9 0.0 3.1e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Response_reg PF00072.24 AAAP01003361.1_3 - 1.8e-22 79.6 0.0 3.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003361.1_3 - 6.4e-16 57.6 0.1 9.5e-16 57.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AAAP01003361.1_3 - 0.00024 20.8 0.9 0.001 18.8 0.0 2.4 2 1 1 3 3 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AAAP01003361.1_3 - 0.00049 19.7 0.1 0.00094 18.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAAP01003361.1_3 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Peripla_BP_1 PF00532.21 AAAP01003361.1_3 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Sigma70_r4 PF04545.16 AAAP01003361.1_3 - 0.022 14.3 0.0 0.065 12.8 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.12 AAAP01003361.1_3 - 0.032 14.2 0.2 0.075 13.0 0.2 1.7 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 AAAP01003361.1_3 - 0.055 12.9 0.3 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AAAP01003361.1_3 - 0.098 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Trans_reg_C PF00486.28 AAAP01003361.1_3 - 0.13 12.4 0.1 40 4.4 0.0 3.1 4 0 0 4 4 4 0 Transcriptional regulatory protein, C terminal HisKA_3 PF07730.13 AAAP01003361.1_4 - 3.5e-08 33.8 0.8 3.5e-08 33.8 0.8 2.3 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AAAP01003361.1_4 - 4.7e-08 33.5 0.2 5.8e-07 30.0 0.2 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003361.1_4 - 0.00028 21.2 0.5 0.00028 21.2 0.5 3.0 3 0 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 AAAP01003361.1_4 - 0.024 14.6 0.5 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain dCache_1 PF02743.18 AAAP01003362.1_1 - 1.4e-11 44.7 0.1 2e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Cache domain Hemerythrin PF01814.23 AAAP01003362.1_1 - 4.3e-07 30.6 2.7 4.3e-07 30.6 2.7 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Gemini_mov PF01708.16 AAAP01003362.1_1 - 0.99 9.2 4.7 0.21 11.4 1.1 1.7 2 0 0 2 2 2 0 Geminivirus putative movement protein Peptidase_M74 PF03411.13 AAAP01003363.1_1 - 1.5e-106 355.3 0.0 1.8e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 Penicillin-insensitive murein endopeptidase PRC PF05239.16 AAAP01003363.1_2 - 1.2e-15 57.3 0.1 1.5e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 PRC-barrel domain DNA_ligase_IV PF11411.8 AAAP01003363.1_2 - 0.18 11.9 0.4 0.31 11.2 0.4 1.3 1 0 0 1 1 1 0 DNA ligase IV Na_H_antiport_1 PF06965.12 AAAP01003363.1_4 - 1.3e-06 27.6 0.3 1.4e-06 27.5 0.3 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 DUF2892 PF11127.8 AAAP01003363.1_4 - 0.18 11.9 2.8 0.24 11.5 2.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) Sigma54_activat PF00158.26 AAAP01003364.1_1 - 1.5e-16 60.6 0.0 3.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01003364.1_1 - 3.1e-11 42.9 0.2 6.3e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Sigma54_activ_2 PF14532.6 AAAP01003364.1_1 - 3.9e-06 27.0 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Hfq PF17209.3 AAAP01003364.1_2 - 3.2e-33 113.2 0.0 3.7e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Hfq protein GTP-bdg_M PF16360.5 AAAP01003364.1_3 - 2.4e-27 95.3 4.6 4.6e-27 94.4 4.6 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 AAAP01003364.1_3 - 2.8e-21 75.7 0.1 7.7e-21 74.3 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 AAAP01003364.1_3 - 1.4e-14 54.5 0.0 3.3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal RsgA_GTPase PF03193.16 AAAP01003364.1_3 - 1.4e-05 25.0 0.0 0.092 12.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 AAAP01003364.1_3 - 2.4e-05 24.9 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter FeoB_N PF02421.18 AAAP01003364.1_3 - 7.4e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAAP01003364.1_3 - 0.0012 18.9 0.0 0.0073 16.4 0.0 2.1 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 AAAP01003364.1_3 - 0.0037 17.7 0.7 0.013 15.9 0.4 2.0 1 1 1 2 2 2 1 AAA ATPase domain cobW PF02492.19 AAAP01003364.1_3 - 0.0086 15.7 1.3 1.5 8.4 0.1 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 AAAP01003364.1_3 - 0.017 14.6 0.0 5.1 6.6 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 AAAP01003364.1_3 - 0.035 14.6 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 AAAP01003364.1_3 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 AAAP01003364.1_3 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoA_transf_3 PF02515.17 AAAP01003365.1_1 - 2.1e-95 320.0 0.0 3.9e-95 319.1 0.0 1.4 1 1 0 1 1 1 1 CoA-transferase family III MRJP PF03022.16 AAAP01003366.1_1 - 9.7e-10 38.3 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 AAAP01003366.1_1 - 9.5e-07 28.6 0.1 0.0084 15.7 0.0 2.8 1 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 AAAP01003366.1_1 - 5.8e-06 26.1 0.6 0.015 15.3 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF_4EBP PF05456.11 AAAP01003366.1_1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF2312 PF10073.9 AAAP01003366.1_2 - 3e-21 74.8 3.6 3.5e-21 74.6 3.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) DUF772 PF05598.11 AAAP01003366.1_3 - 1.5e-16 60.1 0.0 4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AAAP01003366.1_3 - 1e-07 31.8 0.1 1.8e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Transposase DDE domain Ead_Ea22 PF13935.6 AAAP01003366.1_3 - 0.05 14.3 0.1 0.081 13.6 0.1 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF4164 PF13747.6 AAAP01003366.1_3 - 0.05 13.9 7.4 0.53 10.6 6.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) MerR-DNA-bind PF09278.11 AAAP01003366.1_3 - 0.77 10.3 10.0 2.8 8.6 5.6 2.6 1 1 1 2 2 2 0 MerR, DNA binding CheW PF01584.19 AAAP01003367.1_1 - 2.8e-07 30.3 0.0 3.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AAAP01003367.1_2 - 6.9e-18 64.9 0.0 7.5e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheB_methylest PF01339.17 AAAP01003367.1_3 - 5.2e-50 169.5 0.0 8.3e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 AAAP01003367.1_3 - 4.6e-24 84.7 0.0 7.7e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.18 AAAP01003367.1_4 - 6e-56 189.0 0.0 7.9e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAAP01003367.1_4 - 7.2e-12 44.8 0.1 1.4e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 AAAP01003367.1_4 - 3.8e-08 34.0 0.0 1.8e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003367.1_4 - 1.1e-06 29.3 0.0 0.00017 22.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003367.1_4 - 8.6e-06 26.3 0.0 0.00016 22.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003367.1_4 - 2.2e-05 24.3 0.0 0.00026 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003367.1_4 - 0.00031 20.6 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 AAAP01003367.1_4 - 0.035 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein TPMT PF05724.11 AAAP01003367.1_4 - 0.13 11.9 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 AAAP01003367.1_4 - 0.17 11.5 0.0 0.85 9.2 0.0 1.9 2 0 0 2 2 2 0 Nodulation protein S (NodS) OMP_b-brl PF13505.6 AAAP01003368.1_1 - 0.0027 17.9 0.1 0.0033 17.6 0.1 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain ABC_tran PF00005.27 AAAP01003369.1_1 - 2.6e-31 109.0 0.0 8.1e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 AAAP01003369.1_1 - 2.6e-20 72.7 1.7 4.1e-14 52.9 0.3 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AAAP01003369.1_1 - 0.00067 19.2 0.9 0.68 9.3 0.1 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003369.1_1 - 0.0008 19.8 0.3 0.0021 18.5 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003369.1_1 - 0.0045 17.3 2.2 0.018 15.3 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AAAP01003369.1_1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01003369.1_1 - 0.016 15.1 0.1 0.24 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 AAAP01003369.1_1 - 0.023 14.8 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 AAAP01003369.1_1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAAP01003369.1_1 - 0.04 14.4 0.0 0.065 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003369.1_1 - 0.044 14.2 0.1 14 6.1 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAAP01003369.1_1 - 0.09 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 AAAP01003369.1_1 - 0.096 12.3 0.1 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 AAAP01003369.1_1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 AAAP01003369.1_1 - 0.15 12.1 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AAAP01003369.1_1 - 0.16 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 AAAP01003369.1_1 - 0.21 11.3 0.6 13 5.4 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Peptidase_M20 PF01546.28 AAAP01003369.1_2 - 6.1e-21 75.1 0.1 1e-20 74.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 AAAP01003369.1_2 - 2.3e-05 24.2 0.2 5.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 AAAP01003369.1_2 - 0.0018 18.2 0.0 0.0053 16.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Bmp PF02608.14 AAAP01003370.1_1 - 2.3e-34 118.7 0.0 3.2e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like ABC_tran PF00005.27 AAAP01003370.1_2 - 5.6e-43 146.7 0.0 8.4e-31 107.3 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAAP01003370.1_2 - 2.2e-06 27.7 0.2 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003370.1_2 - 0.0019 17.9 0.1 0.0066 16.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01003370.1_2 - 0.004 16.9 0.1 0.014 15.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003370.1_2 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AAAP01003370.1_2 - 0.028 14.9 0.1 0.044 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 AAAP01003370.1_2 - 0.041 14.0 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 AAAP01003370.1_2 - 0.05 14.0 0.3 0.18 12.1 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AAAP01003370.1_2 - 0.055 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_27 PF13514.6 AAAP01003370.1_2 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAAP01003370.1_2 - 0.21 11.0 0.0 2 7.8 0.0 2.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.7 AAAP01003370.1_2 - 0.3 10.0 0.0 5.7 5.7 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain HATPase_c PF02518.26 AAAP01003371.1_2 - 4.8e-25 88.2 0.0 2.6e-24 85.9 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003371.1_2 - 1.6e-11 44.0 0.2 5.8e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003371.1_2 - 0.00067 19.5 0.0 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 1 GHKL domain HATPase_c PF02518.26 AAAP01003372.1_2 - 6.9e-17 62.0 0.0 9.7e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003372.1_2 - 0.0047 16.9 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003372.1_2 - 0.017 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase B12D PF06522.11 AAAP01003372.1_3 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ABC_trans_aux PF03886.13 AAAP01003373.1_1 - 5.4e-08 32.6 0.0 6.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component Baculo_PEP_C PF04513.12 AAAP01003373.1_2 - 0.0011 19.0 1.8 0.94 9.5 0.1 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Mce4_CUP1 PF11887.8 AAAP01003373.1_2 - 0.005 16.3 3.3 1.2 8.5 0.3 2.9 1 1 2 3 3 3 2 Cholesterol uptake porter CUP1 of Mce4, putative DUF2397 PF09660.10 AAAP01003373.1_2 - 0.013 14.4 0.8 0.044 12.7 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2397) WXG100 PF06013.12 AAAP01003373.1_2 - 0.022 15.0 4.3 5.4 7.3 1.6 3.4 2 1 0 3 3 3 0 Proteins of 100 residues with WXG BORCS6 PF10157.9 AAAP01003373.1_2 - 0.031 14.5 0.4 0.36 11.0 0.1 2.4 1 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 CheZ PF04344.13 AAAP01003373.1_2 - 0.051 13.5 0.6 1.4 8.8 0.1 2.2 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ Laminin_II PF06009.12 AAAP01003373.1_2 - 0.11 12.5 3.1 1.7 8.7 0.4 2.6 2 2 0 2 2 2 0 Laminin Domain II Gp-FAR-1 PF05823.12 AAAP01003373.1_2 - 0.15 12.4 0.0 0.74 10.2 0.0 2.0 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HrpB7 PF09486.10 AAAP01003373.1_2 - 0.3 11.5 5.9 0.24 11.8 0.4 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) T7SS_ESX_EspC PF10824.8 AAAP01003373.1_2 - 6.7 7.3 9.8 16 6.1 0.3 3.1 1 1 3 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm MlaD PF02470.20 AAAP01003373.1_3 - 5.7e-07 29.7 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 MlaD protein ABC_tran PF00005.27 AAAP01003373.1_4 - 1.3e-29 103.4 0.0 1.7e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003373.1_4 - 5.7e-06 26.4 0.5 0.00012 22.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003373.1_4 - 0.06 13.7 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01003373.1_4 - 0.082 12.3 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AAAP01003373.1_4 - 0.21 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase TonB_dep_Rec PF00593.24 AAAP01003374.1_1 - 1.8e-43 150.1 20.7 1.8e-43 150.1 20.7 1.6 1 1 1 2 2 2 1 TonB dependent receptor Coprogen_oxidas PF01218.18 AAAP01003374.1_2 - 2.5e-89 298.9 0.0 3.2e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase AAA_30 PF13604.6 AAAP01003374.1_3 - 4.6e-23 81.9 0.0 5.5e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAAP01003374.1_3 - 2.4e-14 53.9 0.0 3.7e-14 53.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 AAAP01003374.1_3 - 2.8e-08 33.3 0.0 7.8e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.18 AAAP01003374.1_3 - 7e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 AAAP01003374.1_3 - 0.00068 20.1 0.0 0.00085 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003374.1_3 - 0.0011 19.3 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003374.1_3 - 0.0024 18.3 0.0 0.0036 17.7 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AAAP01003374.1_3 - 0.0025 17.0 0.0 0.003 16.8 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 AAAP01003374.1_3 - 0.005 16.9 0.0 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AAAP01003374.1_3 - 0.0052 16.7 0.0 0.0065 16.4 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_11 PF13086.6 AAAP01003374.1_3 - 0.0058 16.5 0.5 0.075 12.8 0.6 2.2 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AAAP01003374.1_3 - 0.0059 16.5 0.1 0.38 10.6 0.0 2.1 2 0 0 2 2 2 1 NTPase ATPase_2 PF01637.18 AAAP01003374.1_3 - 0.0079 16.1 0.0 0.015 15.3 0.0 1.4 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea TsaE PF02367.17 AAAP01003374.1_3 - 0.013 15.5 0.1 0.025 14.6 0.1 1.5 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 AAAP01003374.1_3 - 0.028 15.0 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAAP01003374.1_3 - 0.04 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 AAAP01003374.1_3 - 0.055 13.6 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 AAAP01003374.1_3 - 0.084 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 AAAP01003374.1_3 - 0.13 11.9 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003374.1_3 - 0.13 11.8 0.5 0.5 9.9 0.1 2.0 1 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 AAAP01003374.1_3 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Phasin_2 PF09361.10 AAAP01003375.1_2 - 5e-17 62.0 24.0 7.9e-17 61.4 11.1 2.9 1 1 2 3 3 3 2 Phasin protein Prefoldin PF02996.17 AAAP01003375.1_2 - 0.034 14.0 6.1 4.5 7.2 0.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit TPR_20 PF14561.6 AAAP01003375.1_2 - 0.049 14.0 2.4 0.049 14.0 2.4 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat ISG65-75 PF11727.8 AAAP01003375.1_2 - 0.24 10.6 10.0 0.068 12.4 5.5 1.9 1 1 0 2 2 2 0 Invariant surface glycoprotein PIN_8 PF18476.1 AAAP01003375.1_2 - 0.24 11.2 2.6 0.31 10.9 2.2 1.4 1 1 0 1 1 1 0 PIN like domain DUF883 PF05957.13 AAAP01003375.1_2 - 0.5 11.0 15.6 0.61 10.7 5.7 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 AAAP01003375.1_2 - 0.56 10.1 15.2 0.55 10.1 12.7 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain 4HB_MCP_1 PF12729.7 AAAP01003375.1_2 - 4.1 6.9 11.6 15 5.1 3.2 2.8 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction PAS_8 PF13188.7 AAAP01003375.1_4 - 2.7e-11 43.2 0.1 0.00015 21.7 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_9 PF13426.7 AAAP01003375.1_4 - 1.6e-09 38.0 0.0 1.5e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003375.1_4 - 7.4e-09 35.6 0.0 2.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAAP01003375.1_4 - 5e-08 33.2 0.8 2.1e-07 31.2 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS_7 PF12860.7 AAAP01003375.1_4 - 0.026 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold IRF-3 PF10401.9 AAAP01003375.1_4 - 0.17 11.6 0.0 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-regulatory factor 3 HATPase_c PF02518.26 AAAP01003376.1_1 - 8.9e-27 93.8 0.0 1.7e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003376.1_1 - 6.6e-23 81.0 0.0 1.7e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003376.1_1 - 1.1e-15 57.4 1.1 3.6e-15 55.8 0.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01003376.1_1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tmemb_55A PF09788.9 AAAP01003376.1_1 - 0.11 11.6 0.8 2.5 7.1 0.1 2.2 1 1 0 2 2 2 0 Transmembrane protein 55A DUF4330 PF14221.6 AAAP01003376.1_1 - 2.1 8.5 3.7 0.69 10.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) DUF1080 PF06439.11 AAAP01003377.1_2 - 0.0018 18.4 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.24 AAAP01003377.1_2 - 0.0086 16.7 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 AAAP01003377.1_2 - 0.037 14.2 0.0 0.077 13.1 0.0 1.5 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.23 AAAP01003377.1_2 - 0.038 14.2 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Chromate_transp PF02417.15 AAAP01003377.1_3 - 4.5e-58 195.8 42.9 5.7e-34 117.5 16.4 2.4 3 0 0 3 3 3 2 Chromate transporter AIRS PF00586.24 AAAP01003378.1_1 - 9.1e-46 154.5 6.4 4.3e-22 78.6 0.1 2.8 3 0 0 3 3 3 2 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AAAP01003378.1_1 - 7e-35 120.5 0.6 5.3e-34 117.6 0.8 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 AAAP01003378.1_1 - 2.4e-11 44.0 0.0 4.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain 2-Hacid_dh_C PF02826.19 AAAP01003379.1_1 - 2.1e-49 167.3 0.0 2.7e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01003379.1_1 - 5.2e-22 77.9 0.0 5.9e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAAP01003379.1_1 - 0.0042 17.3 0.0 0.0066 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 AAAP01003379.1_1 - 0.045 14.1 0.2 0.11 12.8 0.2 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IlvN PF07991.12 AAAP01003379.1_1 - 0.067 12.8 0.2 0.97 9.0 0.0 2.5 2 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF5375 PF17345.2 AAAP01003379.1_1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5375) F420_oxidored PF03807.17 AAAP01003379.1_1 - 0.091 13.4 0.1 0.2 12.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 AAAP01003379.1_1 - 0.094 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Inh PF02974.14 AAAP01003379.1_2 - 2.3e-19 69.3 0.0 2.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Protease inhibitor Inh DUF2126 PF09899.9 AAAP01003380.1_2 - 7e-284 944.0 0.0 8e-284 943.8 0.0 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) EFG_IV PF03764.18 AAAP01003381.1_1 - 4.1e-44 149.2 0.1 6.6e-44 148.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AAAP01003381.1_1 - 2.6e-32 110.7 0.0 5e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AAAP01003381.1_1 - 4.2e-30 103.6 0.0 9.9e-30 102.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 AAAP01003381.1_1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain GTP_EFTU PF00009.27 AAAP01003381.1_2 - 5e-57 192.6 0.1 6.6e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AAAP01003381.1_2 - 8.6e-28 96.9 0.0 3e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAAP01003381.1_2 - 5.7e-17 61.9 7.7 1.2e-16 60.8 7.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAAP01003381.1_2 - 1.3e-05 25.2 0.2 3.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 AAAP01003381.1_2 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AAAP01003381.1_2 - 0.023 14.6 0.0 0.062 13.2 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase Ribosomal_S10 PF00338.22 AAAP01003381.1_3 - 3.7e-37 126.5 0.2 4.1e-37 126.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L27 PF01016.19 AAAP01003382.1_2 - 7.3e-41 138.1 1.9 8.2e-41 137.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 AAAP01003382.1_3 - 2.3e-37 127.3 0.5 3.1e-37 126.9 0.5 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pirin PF02678.16 AAAP01003382.1_4 - 1.6e-33 114.9 0.2 1e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 AAAP01003382.1_4 - 3.7e-27 94.7 0.0 7.3e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_3 PF05899.12 AAAP01003382.1_4 - 0.024 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF853 PF05872.12 AAAP01003382.1_5 - 5.4e-90 302.4 0.0 6.5e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF2076 PF09849.9 AAAP01003382.1_5 - 0.0015 18.6 1.6 0.071 13.2 0.4 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2076) Zot PF05707.12 AAAP01003382.1_5 - 0.0052 16.4 0.0 0.0073 16.0 0.0 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_10 PF12846.7 AAAP01003382.1_5 - 0.03 13.3 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Hydrolase_6 PF13344.6 AAAP01003382.1_5 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Amino_oxidase PF01593.24 AAAP01003383.1_1 - 8.4e-17 61.6 0.1 3.7e-16 59.5 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SQHop_cyclase_C PF13243.6 AAAP01003383.1_2 - 3.5e-147 489.7 4.6 2.8e-145 483.4 4.5 2.5 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 AAAP01003383.1_2 - 1.7e-124 414.6 1.3 3.4e-114 380.8 0.0 4.3 4 1 0 4 4 4 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 AAAP01003383.1_2 - 1.5e-37 127.0 4.3 1.8e-13 49.9 0.0 6.4 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 AAAP01003383.1_2 - 0.00014 21.3 0.0 0.0093 15.3 0.0 3.1 2 1 1 3 3 3 1 Pectic acid lyase TED_complement PF07678.14 AAAP01003383.1_2 - 0.00026 20.1 0.0 0.018 14.1 0.0 2.9 1 1 1 2 2 2 2 A-macroglobulin TED domain Replic_Relax PF13814.6 AAAP01003383.1_2 - 0.13 12.3 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Replication-relaxation Transposase_mut PF00872.18 AAAP01003384.1_1 - 2.2e-09 36.7 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family Transposase_mut PF00872.18 AAAP01003384.1_2 - 3.1e-07 29.6 0.1 3.5e-07 29.4 0.1 1.0 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS66 PF03050.14 AAAP01003384.1_3 - 6.1e-58 196.5 0.0 7.1e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 AAAP01003384.1_3 - 3.8e-19 68.6 0.7 7.2e-19 67.7 0.7 1.5 1 0 0 1 1 1 1 IS66 C-terminal element Bac_transf PF02397.16 AAAP01003385.1_1 - 3.3e-60 202.9 0.0 4.2e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase FUR PF01475.19 AAAP01003385.1_2 - 9.2e-11 41.9 0.0 4.1e-10 39.9 0.0 1.9 1 1 1 2 2 2 1 Ferric uptake regulator family PadR PF03551.14 AAAP01003385.1_2 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TrmB PF01978.19 AAAP01003385.1_2 - 0.018 14.9 0.0 0.045 13.6 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 AAAP01003385.1_2 - 0.023 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Replic_Relax PF13814.6 AAAP01003385.1_2 - 0.049 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation GGDEF PF00990.21 AAAP01003386.1_1 - 3.7e-52 176.3 0.1 5.5e-52 175.8 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF3365 PF11845.8 AAAP01003386.1_1 - 3.4e-18 66.4 0.0 9.5e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3365) PAS_9 PF13426.7 AAAP01003386.1_1 - 4.7e-18 65.4 0.0 1.4e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003386.1_1 - 2.2e-13 50.2 0.0 5.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003386.1_1 - 8.1e-10 38.9 0.6 1.5e-09 38.0 0.6 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003386.1_1 - 3.6e-08 33.6 1.2 1.4e-07 31.8 0.1 2.5 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 AAAP01003386.1_1 - 1.2e-05 25.2 0.1 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 1 PAS domain EIIA-man PF03610.16 AAAP01003387.1_1 - 1.8e-27 95.9 0.3 2.1e-27 95.6 0.3 1.1 1 0 0 1 1 1 1 PTS system fructose IIA component PTS-HPr PF00381.19 AAAP01003387.1_2 - 3.3e-23 81.7 0.7 4e-23 81.5 0.7 1.1 1 0 0 1 1 1 1 PTS HPr component phosphorylation site CytB6-F_Fe-S PF08802.10 AAAP01003387.1_2 - 1.8 8.7 3.6 0.56 10.3 0.6 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit CobW_C PF07683.14 AAAP01003387.1_3 - 5.3e-20 71.1 0.0 7.4e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain SelP_N PF04592.14 AAAP01003387.1_3 - 6.7 6.1 10.1 8.8 5.7 10.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNA_pol_L_2 PF13656.6 AAAP01003389.1_1 - 0.098 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain FtsJ PF01728.19 AAAP01003389.1_2 - 8.5e-54 182.3 0.0 9.9e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 AAAP01003389.1_2 - 0.0043 16.9 0.0 0.034 13.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAAP01003389.1_2 - 0.0069 16.1 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 AAAP01003389.1_2 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAAP01003389.1_2 - 0.058 13.0 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 AAAP01003389.1_2 - 0.068 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Amidohydro_1 PF01979.20 AAAP01003389.1_3 - 3.8e-10 39.6 0.1 5.2e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003389.1_3 - 0.0045 16.5 0.4 0.011 15.2 0.2 1.6 1 1 1 2 2 2 1 Amidohydrolase family PilS PF08805.11 AAAP01003390.1_1 - 0.00033 20.5 0.4 0.00066 19.5 0.4 1.4 1 0 0 1 1 1 1 PilS N terminal Phage_holin_3_7 PF05449.11 AAAP01003390.1_1 - 0.026 14.5 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 HATPase_c PF02518.26 AAAP01003390.1_2 - 4.6e-15 56.1 0.1 1e-14 55.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003390.1_2 - 4e-12 46.3 0.2 7.9e-11 42.2 0.0 3.0 3 0 0 3 3 3 1 HAMP domain PAS PF00989.25 AAAP01003390.1_2 - 6.6e-08 32.5 0.1 3.4e-07 30.2 0.0 2.3 1 1 1 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003390.1_2 - 1.7e-06 27.9 0.1 5.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 AAAP01003390.1_2 - 6.9e-06 26.3 0.0 2e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003390.1_2 - 1.2e-05 25.6 0.1 6.1e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 PAS fold HisKA PF00512.25 AAAP01003390.1_2 - 0.00011 22.2 0.0 0.00061 19.8 0.0 2.5 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 AAAP01003390.1_2 - 0.025 14.8 0.0 0.28 11.3 0.0 2.5 1 1 1 2 2 2 0 PAS fold JHBP PF06585.11 AAAP01003390.1_2 - 0.029 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) HI0933_like PF03486.14 AAAP01003391.1_1 - 2.1e-70 237.5 0.0 2.5e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 AAAP01003391.1_1 - 5.5e-06 26.2 4.0 0.0017 18.0 1.7 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003391.1_1 - 7.4e-06 25.3 0.4 3e-05 23.3 0.1 2.0 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003391.1_1 - 1.2e-05 25.4 1.3 1.7e-05 25.0 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01003391.1_1 - 2.4e-05 23.7 0.0 6e-05 22.4 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01003391.1_1 - 3.6e-05 23.2 0.2 5.7e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAAP01003391.1_1 - 0.00046 20.7 0.0 0.0029 18.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAAP01003391.1_1 - 0.00082 18.7 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 AAAP01003391.1_1 - 0.0037 16.6 0.1 0.0073 15.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAAP01003391.1_1 - 0.013 15.4 0.4 0.021 14.7 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAAP01003391.1_1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 AAAP01003391.1_1 - 0.033 13.5 1.6 0.046 13.1 1.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003391.1_1 - 0.038 13.2 0.3 0.052 12.8 0.3 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003391.1_1 - 0.041 13.0 1.0 0.056 12.5 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAAP01003391.1_1 - 0.042 12.9 0.3 0.066 12.3 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 AAAP01003391.1_1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 AAAP01003391.1_1 - 0.12 12.3 0.4 0.28 11.2 0.2 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding MDMPI_N PF11716.8 AAAP01003391.1_1 - 0.13 13.0 0.1 0.13 13.0 0.1 2.9 2 1 1 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain NAD_binding_2 PF03446.15 AAAP01003391.1_1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TerC PF03741.16 AAAP01003391.1_2 - 6.6e-54 182.3 11.8 6.6e-54 182.3 11.8 1.7 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF475 PF04332.15 AAAP01003391.1_2 - 0.042 13.6 16.7 0.023 14.5 7.9 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF475) DJ-1_PfpI PF01965.24 AAAP01003391.1_4 - 3.7e-52 176.4 0.1 4.5e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AAAP01003391.1_4 - 3.3e-05 23.7 0.0 0.025 14.3 0.0 2.1 2 0 0 2 2 2 2 ThiJ/PfpI family-like GATase_3 PF07685.14 AAAP01003391.1_4 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Glyco_transf_4 PF13439.6 AAAP01003392.1_1 - 0.029 14.4 0.0 0.03 14.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01003392.1_1 - 0.056 13.9 0.0 0.061 13.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAAP01003392.1_2 - 2.3e-21 76.0 0.2 6.1e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003392.1_3 - 0.0013 19.0 0.2 0.0017 18.7 0.2 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003392.1_3 - 0.087 12.4 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003392.1_4 - 1.1e-19 71.0 0.3 1.6e-19 70.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01003392.1_4 - 2.1e-18 67.3 15.8 2.1e-18 67.3 15.8 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AAAP01003392.1_4 - 0.033 14.2 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF4864 PF16156.5 AAAP01003393.1_1 - 1.2e-30 106.2 0.0 1.4e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4864) ParE_toxin PF05016.15 AAAP01003393.1_1 - 0.036 14.7 0.2 0.05 14.2 0.2 1.2 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Thr_synth_N PF14821.6 AAAP01003393.1_2 - 2.2e-26 91.9 0.0 9.8e-26 89.8 0.0 2.2 2 1 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 AAAP01003393.1_2 - 1.1e-16 61.1 0.0 2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1 PF00133.22 AAAP01003394.1_1 - 4.8e-176 586.6 0.8 9.9e-175 582.2 0.8 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01003394.1_1 - 1.5e-13 50.3 0.2 2e-07 30.1 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AAAP01003394.1_1 - 6.7e-07 29.0 0.1 0.0006 19.4 0.0 2.2 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 CN_hydrolase PF00795.22 AAAP01003395.1_1 - 4.4e-44 150.8 0.0 5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase OprB PF04966.12 AAAP01003395.1_2 - 1e-33 117.3 10.3 1.5e-33 116.7 10.3 1.2 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family HAMP PF00672.25 AAAP01003396.1_1 - 2.5e-11 43.8 9.2 6.9e-11 42.4 2.4 2.7 1 1 1 2 2 2 2 HAMP domain HisKA PF00512.25 AAAP01003396.1_1 - 0.00031 20.7 1.6 0.00087 19.3 0.1 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 AAAP01003396.1_1 - 0.042 14.1 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3540 PF12059.8 AAAP01003396.1_1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) DUF4164 PF13747.6 AAAP01003396.1_1 - 0.16 12.3 3.4 2.3 8.6 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Trans_reg_C PF00486.28 AAAP01003396.1_2 - 9.7e-29 99.3 0.0 1.6e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01003396.1_2 - 3.6e-23 81.9 0.0 5.7e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain OsmC PF02566.19 AAAP01003396.1_3 - 5.7e-18 65.2 0.0 9.8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein ABC_tran PF00005.27 AAAP01003396.1_4 - 0.0079 16.7 0.0 0.016 15.7 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SbcCD_C PF13558.6 AAAP01003396.1_4 - 0.12 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CHASE3 PF05227.13 AAAP01003397.1_1 - 1.7e-34 118.7 10.1 1.7e-34 118.7 10.1 1.9 2 0 0 2 2 2 1 CHASE3 domain PAS_7 PF12860.7 AAAP01003397.1_1 - 2.3e-23 82.5 0.0 6.3e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAAP01003397.1_1 - 0.00011 22.2 0.4 0.00073 19.5 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SPOB_a PF14689.6 AAAP01003397.1_1 - 0.0018 18.0 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain PAS_4 PF08448.10 AAAP01003397.1_1 - 0.02 15.1 0.7 0.17 12.2 0.1 2.9 3 1 0 3 3 3 0 PAS fold PAS_8 PF13188.7 AAAP01003397.1_1 - 0.11 12.6 0.0 0.96 9.5 0.0 2.6 2 0 0 2 2 2 0 PAS domain DUF2207 PF09972.9 AAAP01003397.1_1 - 0.38 9.5 0.6 0.81 8.4 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PAS_3 PF08447.12 AAAP01003397.1_2 - 4e-36 123.2 0.1 9.1e-20 70.7 0.3 2.4 2 0 0 2 2 2 2 PAS fold HWE_HK PF07536.14 AAAP01003397.1_2 - 6.1e-25 87.7 0.1 1.3e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 HWE histidine kinase PAS_4 PF08448.10 AAAP01003397.1_2 - 1.1e-06 28.8 3.7 0.001 19.3 0.3 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003397.1_2 - 1.2e-06 28.7 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003397.1_2 - 6.4e-06 26.1 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold HisKA_2 PF07568.12 AAAP01003397.1_2 - 0.00013 21.9 0.0 0.00039 20.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase HATPase_c_2 PF13581.6 AAAP01003397.1_2 - 0.004 17.1 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain bMG10 PF17973.1 AAAP01003397.1_2 - 0.095 12.9 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF2243 PF10002.9 AAAP01003398.1_2 - 4.2e-56 188.9 13.2 4.9e-56 188.7 13.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DUF2784 PF10861.8 AAAP01003398.1_2 - 0.05 13.6 2.3 0.05 13.6 2.3 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF2784) DUF3040 PF11239.8 AAAP01003398.1_2 - 0.45 10.8 6.7 28 5.0 0.4 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) DUF998 PF06197.13 AAAP01003398.1_2 - 3.1 7.4 17.8 0.38 10.3 12.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) NTP_transf_3 PF12804.7 AAAP01003398.1_5 - 1.4e-21 77.5 6.2 1.5e-21 77.4 6.2 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AAAP01003398.1_5 - 9.2e-12 45.1 0.1 1.1e-11 44.8 0.1 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 AAAP01003398.1_5 - 8.4e-10 38.8 0.7 1.1e-09 38.3 0.7 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2064 PF09837.9 AAAP01003398.1_5 - 0.00073 19.4 0.2 0.0015 18.4 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) CTP_transf_3 PF02348.19 AAAP01003398.1_5 - 0.0091 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NBD_C PF17042.5 AAAP01003398.1_5 - 0.052 14.1 1.1 0.078 13.5 1.1 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Sulfatase PF00884.23 AAAP01003399.1_1 - 0.0073 15.7 0.0 0.0083 15.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase SfsA_N PF17746.1 AAAP01003399.1_1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.5 1 1 0 1 1 1 0 SfsA N-terminal OB domain Poly_export PF02563.16 AAAP01003399.1_2 - 6.7e-15 55.1 0.1 2.6e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AAAP01003399.1_2 - 0.023 14.5 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 SLBB domain Methyltransf_5 PF01795.19 AAAP01003400.1_1 - 1.5e-47 162.7 0.0 1.7e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 AAAP01003400.1_1 - 9.7e-05 23.0 0.1 0.0002 22.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003400.1_1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 AAAP01003400.1_1 - 0.038 15.0 0.1 0.067 14.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003400.1_1 - 0.12 13.1 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003400.1_1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain BRCT PF00533.26 AAAP01003400.1_3 - 3.8e-14 52.8 0.0 5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 AAAP01003400.1_3 - 1.8e-05 24.6 0.1 2.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 twin BRCT domain Bep_C_terminal PF17841.1 AAAP01003400.1_3 - 0.00026 21.1 0.1 0.00042 20.5 0.1 1.3 1 0 0 1 1 1 1 BID domain of Bartonella effector protein (Bep) DUF4839 PF16127.5 AAAP01003400.1_3 - 0.09 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) zf-HC2 PF13490.6 AAAP01003400.1_4 - 0.032 14.5 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 Putative zinc-finger DNA_ligase_OB PF03120.16 AAAP01003400.1_5 - 8.1e-14 51.3 0.1 1.2e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain DNA_ligase_ZBD PF03119.16 AAAP01003400.1_5 - 8.6e-11 41.7 1.9 1.9e-10 40.6 1.9 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain HHH_2 PF12826.7 AAAP01003400.1_5 - 0.00068 19.7 0.0 0.0033 17.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif MazE_antitoxin PF04014.18 AAAP01003400.1_5 - 0.084 12.8 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin DUF4130 PF13566.6 AAAP01003401.1_1 - 3.9e-41 140.5 0.0 4.9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4130 UDG PF03167.19 AAAP01003401.1_2 - 3.2e-32 111.7 0.0 4.2e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ADH_N PF08240.12 AAAP01003401.1_3 - 1.1e-28 99.2 0.9 1.8e-28 98.6 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAAP01003401.1_3 - 1e-12 48.2 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 AAAP01003401.1_3 - 9.6e-12 44.6 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 AAAP01003401.1_3 - 0.0097 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_4 PF08386.10 AAAP01003402.1_2 - 8e-05 22.7 0.1 0.00019 21.5 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Ser_hydrolase PF06821.13 AAAP01003402.1_2 - 0.035 14.0 0.0 0.043 13.7 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 AAAP01003402.1_2 - 0.069 12.4 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Flavin_Reduct PF01613.18 AAAP01003402.1_3 - 6.9e-37 126.9 0.0 8.2e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain FAD_binding_5 PF00941.21 AAAP01003402.1_5 - 1.8e-20 73.4 0.0 2.4e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase ACR_tran PF00873.19 AAAP01003403.1_1 - 7.2e-108 361.6 7.2 8.6e-108 361.4 7.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3606 PF12244.8 AAAP01003403.1_1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) HlyD_D23 PF16576.5 AAAP01003403.1_2 - 1.1e-09 37.8 0.4 2.7e-09 36.6 0.4 1.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003403.1_2 - 6.4e-07 30.0 4.1 1.6e-06 28.8 0.8 2.9 2 1 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.20 AAAP01003403.1_2 - 0.014 15.3 3.5 0.014 15.3 3.5 2.2 2 0 0 2 2 2 0 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003403.1_2 - 0.035 13.9 7.8 0.21 11.4 0.3 3.0 3 0 0 3 3 3 0 Biotin-lipoyl like Big_9 PF17963.1 AAAP01003404.1_1 - 2.8e-29 101.7 92.8 6.7e-07 30.0 16.3 5.2 5 0 0 5 5 5 5 Bacterial Ig domain Cadherin_4 PF17803.1 AAAP01003404.1_1 - 6.6e-24 84.3 88.7 1.1e-05 25.9 14.5 5.5 5 0 0 5 5 5 5 Bacterial cadherin-like domain DUF5643 PF18705.1 AAAP01003404.1_1 - 3.4e-09 36.7 14.3 0.14 12.2 0.3 4.3 4 0 0 4 4 4 4 Family of unknown function (DUF5643) GbpA_2 PF18416.1 AAAP01003404.1_1 - 1.4e-06 28.5 6.4 8.4 6.7 0.0 5.5 5 0 0 5 5 5 4 N-acetylglucosamine binding protein domain 2 YbbR PF07949.12 AAAP01003404.1_1 - 2.2e-05 24.7 17.3 9.9 6.6 0.1 7.8 5 4 4 9 9 9 0 YbbR-like protein DUF4959 PF16323.5 AAAP01003404.1_1 - 0.00032 21.0 1.4 52 4.2 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4959) bMG6 PF17962.1 AAAP01003404.1_1 - 0.00034 20.7 1.6 21 5.3 0.0 5.2 4 3 0 4 4 4 0 Bacterial macroglobulin domain 6 DUF4369 PF14289.6 AAAP01003404.1_1 - 0.00039 20.9 9.9 16 6.1 0.1 5.1 4 3 0 4 4 4 0 Domain of unknown function (DUF4369) Sipho_tail PF05709.11 AAAP01003404.1_1 - 0.00053 19.5 30.8 2 7.7 3.6 5.1 1 1 3 5 5 5 4 Phage tail protein DUF2745 PF10922.8 AAAP01003404.1_1 - 0.0032 17.7 1.2 1e+02 3.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2745) DUF4998 PF16389.5 AAAP01003404.1_1 - 0.0034 17.0 3.6 39 3.8 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function GUB_WAK_bind PF13947.6 AAAP01003404.1_1 - 0.046 14.5 0.2 2.4e+02 2.5 0.0 4.4 3 1 0 4 4 4 0 Wall-associated receptor kinase galacturonan-binding EcoRI PF02963.16 AAAP01003404.1_1 - 0.051 12.6 0.0 63 2.4 0.0 3.7 4 0 0 4 4 4 0 Restriction endonuclease EcoRI YmzC PF14157.6 AAAP01003404.1_1 - 0.43 10.7 21.4 15 5.7 0.7 4.7 4 0 0 4 4 4 0 YmzC-like protein CBM39 PF15886.5 AAAP01003404.1_1 - 1.1 9.1 12.8 26 4.8 0.2 4.2 4 0 0 4 4 4 0 Carbohydrate binding domain (family 32) Phage_Mu_Gp45 PF06890.12 AAAP01003404.1_1 - 3.9 7.3 18.7 9.6 6.0 0.3 5.1 5 0 0 5 5 5 0 Bacteriophage Mu Gp45 protein HYR PF02494.16 AAAP01003404.1_1 - 4 7.8 25.5 17 5.8 0.3 6.4 1 1 6 8 8 8 0 HYR domain Big_6 PF17936.1 AAAP01003404.1_1 - 4.1 7.7 61.1 18 5.7 8.1 8.3 4 4 1 5 5 5 0 Bacterial Ig domain DUF4436 PF14494.6 AAAP01003404.1_1 - 8.1 5.6 14.3 21 4.3 0.2 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4436) DUF5643 PF18705.1 AAAP01003404.1_2 - 0.035 14.1 0.2 0.043 13.8 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5643) UDPG_MGDP_dh_N PF03721.14 AAAP01003405.1_3 - 2.1e-66 223.1 0.0 2.9e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAAP01003405.1_3 - 2e-39 133.7 0.1 1e-38 131.4 0.0 2.3 3 0 0 3 3 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAAP01003405.1_3 - 1.9e-34 118.2 0.0 1.5e-31 108.9 0.0 2.7 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 AAAP01003405.1_3 - 0.00032 20.9 0.1 0.098 12.8 0.0 3.1 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 AAAP01003405.1_3 - 0.00078 19.1 0.0 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AAAP01003405.1_3 - 0.00084 19.3 0.0 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AAAP01003405.1_3 - 0.0018 18.3 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 AAAP01003405.1_3 - 0.0097 16.5 0.3 0.054 14.1 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003405.1_3 - 0.025 13.9 0.3 0.059 12.7 0.3 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AAAP01003405.1_3 - 0.025 13.8 0.0 0.055 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003405.1_3 - 0.027 14.7 0.2 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 AAAP01003405.1_3 - 0.03 14.6 0.4 1.7 8.9 0.0 3.4 3 0 0 3 3 3 0 TrkA-N domain FAD_binding_3 PF01494.19 AAAP01003405.1_3 - 0.037 13.3 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.26 AAAP01003405.1_3 - 5.3 7.0 5.9 11 6.1 0.0 3.5 4 1 1 5 5 5 0 Zinc-binding dehydrogenase DUF2388 PF09498.10 AAAP01003406.1_1 - 0.18 11.8 0.9 3.3 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) adh_short_C2 PF13561.6 AAAP01003406.1_3 - 4.4e-62 209.7 10.2 5e-62 209.5 10.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003406.1_3 - 1.4e-51 174.7 8.7 1.7e-51 174.4 8.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003406.1_3 - 7.2e-14 52.1 4.4 1.2e-13 51.4 4.4 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AAAP01003406.1_3 - 2.1e-05 24.0 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 AAAP01003406.1_3 - 0.006 15.9 1.7 0.011 15.0 1.6 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 AAAP01003406.1_3 - 0.11 12.0 0.8 0.18 11.2 0.8 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HTH_20 PF12840.7 AAAP01003406.1_4 - 2.7e-13 49.8 0.1 4.2e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAAP01003406.1_4 - 0.0012 18.7 0.1 0.0028 17.5 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 AAAP01003406.1_4 - 0.13 12.4 0.0 0.72 10.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain Lactamase_B_2 PF12706.7 AAAP01003407.1_1 - 1.2e-15 57.6 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TENA_THI-4 PF03070.16 AAAP01003407.1_2 - 9.9e-55 185.6 0.0 1.2e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PqqD PF05402.12 AAAP01003407.1_2 - 4.7e-13 49.2 0.1 2e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) DUF1967 PF09269.11 AAAP01003407.1_2 - 0.18 11.7 0.1 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Ald_Xan_dh_C2 PF02738.18 AAAP01003408.1_2 - 5.2e-83 279.4 0.0 7.8e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 AAAP01003408.1_2 - 4.2e-34 117.7 0.2 7e-34 117.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01003408.1_2 - 4.1e-27 94.7 0.1 6.6e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 AAAP01003408.1_2 - 6.6e-07 29.5 0.1 2.1e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_4 PF01565.23 AAAP01003408.1_2 - 0.038 13.7 0.2 0.13 12.0 0.2 1.9 1 1 0 1 1 1 0 FAD binding domain VWA_CoxE PF05762.14 AAAP01003409.1_1 - 4.1e-44 150.6 0.1 4.6e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 AAAP01003409.1_1 - 0.00012 22.7 0.0 0.0002 22.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2201 PF09967.9 AAAP01003409.1_1 - 0.011 15.8 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 VWA-like domain (DUF2201) VWA PF00092.28 AAAP01003409.1_1 - 0.063 13.5 0.2 0.34 11.1 0.2 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain SUV3_C PF12513.8 AAAP01003409.1_2 - 2.2e-12 46.7 0.1 4.4e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 AAAP01003409.1_2 - 6.9e-11 42.5 0.0 1.8e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 AAAP01003409.1_2 - 8.7e-08 31.9 0.0 2.9e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 DEAD PF00270.29 AAAP01003409.1_2 - 0.12 12.2 0.0 0.54 10.0 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 AAAP01003409.1_2 - 0.21 11.5 0.0 0.8 9.6 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Plug PF07715.15 AAAP01003410.1_1 - 8.7e-20 71.3 0.1 2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain rve_3 PF13683.6 AAAP01003410.1_2 - 1.7e-24 85.4 0.1 3.5e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AAAP01003410.1_2 - 5.8e-18 65.2 0.0 1.1e-17 64.3 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AAAP01003410.1_2 - 0.032 14.5 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 DDE domain rve_2 PF13333.6 AAAP01003410.1_2 - 0.041 14.0 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Peripla_BP_6 PF13458.6 AAAP01003410.1_3 - 1.8e-33 116.6 1.6 2.3e-33 116.3 1.6 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003410.1_3 - 8.8e-06 24.9 0.1 0.0019 17.3 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003410.1_3 - 1.9e-05 23.9 0.0 3.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region GerE PF00196.19 AAAP01003411.1_1 - 6.4e-17 60.8 0.3 1.1e-16 60.2 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAAP01003411.1_1 - 4.2e-15 55.9 0.0 5.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAAP01003411.1_1 - 3.7e-06 26.5 0.1 1.6e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAAP01003411.1_1 - 0.00021 21.0 0.1 0.0004 20.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAAP01003411.1_1 - 0.00024 20.6 1.5 0.00045 19.7 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_40 PF14493.6 AAAP01003411.1_1 - 0.0057 17.1 0.2 0.013 15.9 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain DUF742 PF05331.11 AAAP01003411.1_1 - 0.0057 16.5 1.2 0.011 15.6 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF742) HTH_24 PF13412.6 AAAP01003411.1_1 - 0.021 14.4 0.1 0.054 13.1 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAAP01003411.1_1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain LexA_DNA_bind PF01726.16 AAAP01003411.1_1 - 0.11 12.2 0.2 0.66 9.8 0.2 2.1 1 1 0 1 1 1 0 LexA DNA binding domain HTH_AsnC-type PF13404.6 AAAP01003411.1_1 - 0.28 11.0 1.7 0.79 9.6 0.0 2.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain UvrB_inter PF17757.1 AAAP01003412.1_3 - 2.9e-27 94.7 0.1 1.5e-26 92.4 0.0 2.2 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 AAAP01003412.1_3 - 1.5e-23 82.3 1.2 1.9e-22 78.8 0.3 2.4 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AAAP01003412.1_3 - 1.8e-17 63.7 0.1 3.7e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAAP01003412.1_3 - 9.7e-12 45.2 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UVR PF02151.19 AAAP01003412.1_3 - 1e-08 34.7 6.9 2.4e-08 33.4 6.9 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 AAAP01003412.1_3 - 1.3e-05 25.1 0.0 5.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AAAP01003412.1_3 - 2.6e-05 24.0 0.1 0.0021 17.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 AAAP01003412.1_3 - 0.023 14.8 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Microtub_bd PF16796.5 AAAP01003412.1_3 - 0.027 14.4 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding AAA_22 PF13401.6 AAAP01003412.1_3 - 0.043 14.1 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 AAAP01003412.1_3 - 0.082 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Kinesin PF00225.23 AAAP01003412.1_3 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_19 PF13245.6 AAAP01003412.1_3 - 0.12 12.8 0.1 8 6.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Glyco_tran_28_C PF04101.16 AAAP01003413.1_1 - 6.6e-05 23.0 0.0 9.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 AAAP01003413.1_1 - 0.025 13.4 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Lipase_GDSL_2 PF13472.6 AAAP01003413.1_2 - 0.013 15.9 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family 4HB_MCP_1 PF12729.7 AAAP01003414.1_2 - 2.7e-12 46.6 0.5 4.6e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003414.1_2 - 7.1e-10 39.1 0.3 1.9e-09 37.7 0.3 1.8 1 0 0 1 1 1 1 HAMP domain TarH PF02203.15 AAAP01003414.1_2 - 1.8e-06 28.0 6.0 1.8e-06 28.0 6.0 1.8 2 0 0 2 2 2 1 Tar ligand binding domain homologue ACR_tran PF00873.19 AAAP01003415.1_1 - 3e-216 720.4 0.1 3.7e-216 720.1 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003415.1_1 - 1.2e-10 40.9 17.0 1.2e-10 40.9 17.0 1.6 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 AAAP01003415.1_1 - 0.015 14.7 12.9 0.028 13.8 12.9 1.3 1 0 0 1 1 1 0 Protein export membrane protein HlyD PF00529.20 AAAP01003415.1_2 - 0.00011 22.0 2.6 0.00011 22.0 1.5 1.5 2 0 0 2 2 2 1 HlyD membrane-fusion protein of T1SS GATase_5 PF13507.6 AAAP01003416.1_1 - 2.6e-15 56.2 0.0 3.2e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Pribosyltran PF00156.27 AAAP01003416.1_2 - 9e-17 61.0 0.2 1.1e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAAP01003416.1_2 - 1.6e-05 24.4 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AAAP01003416.1_2 - 0.02 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Inositol_P PF00459.25 AAAP01003416.1_3 - 1.7e-62 211.4 0.0 1.9e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AAAP01003416.1_3 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Fer4_7 PF12838.7 AAAP01003418.1_1 - 6.8e-06 26.6 5.2 0.0005 20.6 0.7 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.6 AAAP01003418.1_1 - 0.0033 17.5 1.9 0.13 12.4 1.9 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003418.1_1 - 0.013 16.4 0.2 0.058 14.3 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4 PF00037.27 AAAP01003418.1_1 - 0.021 14.6 4.0 0.12 12.3 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003418.1_1 - 0.18 11.9 2.2 2.7 8.2 2.9 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain NrfD PF03916.14 AAAP01003418.1_2 - 2.3e-17 63.6 30.5 3.8e-17 62.9 30.5 1.3 1 0 0 1 1 1 1 Polysulphide reductase, NrfD DUF3341 PF11821.8 AAAP01003418.1_3 - 3.4e-50 170.0 0.1 3.8e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) HATPase_c PF02518.26 AAAP01003419.1_1 - 4.4e-21 75.5 0.2 6.7e-21 74.9 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003419.1_1 - 0.00048 20.1 0.0 0.0075 16.3 0.0 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01003419.1_1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01003419.1_1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAAP01003419.1_1 - 0.048 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Tht1 PF04163.12 AAAP01003419.1_1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein HDOD PF08668.12 AAAP01003419.1_2 - 2.8e-41 141.2 0.0 3.8e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Response_reg PF00072.24 AAAP01003419.1_2 - 3.2e-17 62.7 0.0 6.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Castor1_N PF18700.1 AAAP01003419.1_2 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Sacchrp_dh_NADP PF03435.18 AAAP01003420.1_1 - 1e-32 113.1 0.0 1.3e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AAAP01003420.1_1 - 0.0029 18.1 0.1 0.0043 17.6 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 AAAP01003420.1_1 - 0.055 13.7 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain MFS_4 PF06779.14 AAAP01003420.1_3 - 5.6e-36 124.6 21.6 6.3e-36 124.4 21.6 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 AAAP01003420.1_3 - 1.8e-08 33.7 31.1 2.1e-08 33.5 31.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Plug PF07715.15 AAAP01003421.1_1 - 5.6e-18 65.5 1.7 8.1e-18 65.0 0.4 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AAAP01003421.1_1 - 9.7e-16 58.7 6.2 9.7e-16 58.7 6.2 1.5 2 0 0 2 2 2 1 TonB dependent receptor Urate_ox_N PF06181.11 AAAP01003422.1_1 - 5.7e-63 213.0 0.5 7.5e-63 212.6 0.5 1.1 1 0 0 1 1 1 1 Urate oxidase N-terminal Cytochrome_CBB3 PF13442.6 AAAP01003422.1_1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003422.1_1 - 0.19 12.9 0.4 2.4 9.4 0.4 2.2 1 1 0 1 1 1 0 Cytochrome c DUF3382 PF11862.8 AAAP01003422.1_1 - 0.26 11.6 5.4 0.18 12.1 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF4231 PF14015.6 AAAP01003422.1_1 - 1.2 9.6 4.2 7.9 7.0 4.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Amidohydro_1 PF01979.20 AAAP01003422.1_2 - 4.1e-57 194.1 0.1 4.8e-57 193.8 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003422.1_2 - 1.1e-07 31.8 11.3 3.8e-05 23.4 1.8 2.3 1 1 0 2 2 2 2 Amidohydrolase family HTH_18 PF12833.7 AAAP01003424.1_1 - 5.2e-16 58.7 0.5 1.2e-15 57.5 0.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003424.1_1 - 2.8e-09 36.9 0.0 2e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 AAAP01003424.1_1 - 5.1e-08 32.8 2.5 5.1e-08 32.8 2.5 1.9 2 1 1 3 3 3 1 AraC-binding-like domain HTH_23 PF13384.6 AAAP01003424.1_1 - 0.0039 16.9 0.1 0.01 15.6 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Epimerase PF01370.21 AAAP01003424.1_2 - 9.6e-24 84.2 0.1 1.2e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003424.1_2 - 9.5e-22 77.8 0.0 1e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003424.1_2 - 4.9e-19 68.4 0.1 6e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAAP01003424.1_2 - 3e-12 46.8 1.3 3.7e-12 46.5 1.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AAAP01003424.1_2 - 2.9e-09 36.5 0.0 3.8e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 AAAP01003424.1_2 - 1.2e-07 31.4 0.1 1.8e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003424.1_2 - 5.3e-05 23.2 0.6 0.00016 21.7 0.6 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 AAAP01003424.1_2 - 9.1e-05 22.1 0.5 0.00022 20.9 0.5 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 AAAP01003424.1_2 - 9.2e-05 21.7 0.1 0.018 14.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003424.1_2 - 0.0018 17.4 0.1 0.0022 17.2 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 AAAP01003424.1_2 - 0.019 15.2 0.1 0.027 14.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 AAAP01003424.1_2 - 0.021 14.7 0.1 0.024 14.5 0.1 1.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAAP01003424.1_2 - 0.035 14.4 0.1 0.052 13.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 AAAP01003424.1_2 - 0.078 13.0 1.0 0.17 11.8 1.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 MCPsignal PF00015.21 AAAP01003425.1_1 - 9.9e-31 106.9 27.3 9.9e-31 106.9 27.3 3.3 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003425.1_1 - 2.4e-05 24.6 0.1 0.00024 21.4 0.0 2.8 2 0 0 2 2 2 1 HAMP domain DUF948 PF06103.11 AAAP01003425.1_1 - 0.1 12.9 31.9 0.51 10.6 1.2 6.4 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003425.1_1 - 0.27 11.3 20.1 0.38 10.8 2.2 4.6 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) DUF1837 PF08878.11 AAAP01003425.1_1 - 0.5 10.1 3.5 0.2 11.4 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) Syntaxin_2 PF14523.6 AAAP01003425.1_1 - 2.9 8.3 12.9 10 6.6 3.3 3.8 3 2 0 3 3 3 0 Syntaxin-like protein DUF3450 PF11932.8 AAAP01003425.1_1 - 3 7.1 20.9 1.3 8.3 5.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 AAAP01003425.1_1 - 4.8 7.3 9.1 0.16 12.0 1.2 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3042 PF11240.8 AAAP01003425.1_1 - 10 6.3 9.1 3.2 7.8 1.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3042) DAO PF01266.24 AAAP01003426.1_1 - 4.1e-53 181.2 2.8 4.6e-53 181.0 2.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003426.1_1 - 0.00061 19.0 0.3 0.00097 18.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 AAAP01003426.1_1 - 0.0015 17.3 0.0 0.0022 16.8 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 AAAP01003426.1_1 - 0.06 12.2 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ThiS PF02597.20 AAAP01003426.1_2 - 2.7e-14 53.5 0.1 3.3e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ThiS family Ub-RnfH PF03658.14 AAAP01003426.1_2 - 0.02 15.3 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 RnfH family Ubiquitin Lambda_tail_I PF06805.12 AAAP01003426.1_2 - 0.1 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I ThiG PF05690.14 AAAP01003426.1_3 - 1.4e-105 352.1 1.7 1.6e-105 351.9 1.7 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AAAP01003426.1_3 - 0.00034 20.2 0.2 0.00081 18.9 0.1 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AAAP01003426.1_3 - 0.0017 17.5 2.4 0.0025 16.9 1.8 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 AAAP01003426.1_3 - 0.014 14.6 0.6 0.022 13.9 0.6 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase IMPDH PF00478.25 AAAP01003426.1_3 - 0.017 14.2 2.0 0.026 13.5 2.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF561 PF04481.12 AAAP01003426.1_3 - 0.02 14.1 0.2 0.032 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.17 AAAP01003426.1_4 - 4.6e-39 133.6 0.0 5.7e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase Haem_degrading PF03928.14 AAAP01003426.1_5 - 7.5e-06 26.0 2.2 7.7e-06 26.0 2.2 1.0 1 0 0 1 1 1 1 Haem-degrading Haem_degrading PF03928.14 AAAP01003426.1_6 - 2.8e-10 40.3 0.0 3.3e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading Peptidase_M17 PF00883.21 AAAP01003427.1_1 - 4.2e-97 325.2 0.0 5.4e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain OMP_b-brl PF13505.6 AAAP01003427.1_2 - 0.00023 21.4 2.8 0.00026 21.2 2.8 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain CSD PF00313.22 AAAP01003427.1_3 - 6.2e-38 128.5 0.7 1.3e-21 76.2 0.1 2.1 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01003427.1_3 - 1.4e-09 37.5 0.8 0.00031 20.3 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain S1 PF00575.23 AAAP01003427.1_3 - 4.2e-05 23.8 0.0 0.063 13.6 0.0 2.2 2 0 0 2 2 2 2 S1 RNA binding domain Keratin_2_tail PF16210.5 AAAP01003427.1_3 - 8.9 6.6 28.2 11 6.3 15.5 2.4 2 0 0 2 2 2 0 Keratin type II cytoskeletal 1 tail Response_reg PF00072.24 AAAP01003427.1_4 - 2.8e-17 62.9 0.0 3.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain NUDIX PF00293.28 AAAP01003428.1_1 - 0.00062 19.8 0.0 0.0008 19.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TruB_C_2 PF16198.5 AAAP01003428.1_2 - 1.4 9.1 4.5 16 5.7 0.1 3.0 4 1 0 4 4 4 0 tRNA pseudouridylate synthase B C-terminal domain ABC_tran PF00005.27 AAAP01003428.1_3 - 7.3e-20 71.9 0.0 8.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01003428.1_3 - 0.00013 22.4 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003428.1_3 - 0.0023 18.2 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003428.1_3 - 0.0026 17.7 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAAP01003428.1_3 - 0.005 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01003428.1_3 - 0.0051 16.5 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAAP01003428.1_3 - 0.0095 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_21 PF13304.6 AAAP01003428.1_3 - 0.021 14.7 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 AAAP01003428.1_3 - 0.048 13.2 0.1 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AAAP01003428.1_3 - 0.067 12.9 0.0 0.08 12.6 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01003428.1_3 - 0.082 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AAAP01003428.1_3 - 0.095 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AAAP01003428.1_3 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 AAAP01003428.1_3 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 AAAP01003428.1_3 - 0.15 11.2 0.0 0.18 10.9 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 AAAP01003428.1_3 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 AAAP01003428.1_3 - 0.18 12.0 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003428.1_3 - 0.2 12.0 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AAAP01003428.1_3 - 0.21 11.9 0.0 0.3 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain SNase PF00565.17 AAAP01003428.1_5 - 3.9e-07 30.5 0.0 5.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF4695 PF15766.5 AAAP01003428.1_6 - 0.062 13.5 0.2 0.082 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) FAD_binding_2 PF00890.24 AAAP01003429.1_2 - 8.4e-128 427.0 3.7 1.1e-127 426.6 3.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAAP01003429.1_2 - 7.3e-44 148.8 0.3 1.1e-43 148.3 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 AAAP01003429.1_2 - 0.00032 19.9 3.9 0.075 12.1 2.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 AAAP01003429.1_2 - 0.0024 17.2 1.5 0.0051 16.1 0.7 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAAP01003429.1_2 - 0.012 14.8 0.6 0.11 11.7 0.2 2.4 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 AAAP01003429.1_2 - 0.022 14.0 0.7 0.022 14.0 0.7 1.9 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.14 AAAP01003429.1_2 - 0.05 12.3 1.0 0.16 10.7 0.5 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 AAAP01003429.1_2 - 0.38 10.0 6.0 3.3 6.9 4.2 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 AAAP01003429.1_2 - 0.64 9.5 8.8 3.8 7.0 5.3 2.9 2 2 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003429.1_2 - 1.6 7.9 3.5 3.2 6.9 1.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4145 PF13643.6 AAAP01003430.1_1 - 1.9e-07 31.1 0.1 2.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) GrlR PF16518.5 AAAP01003430.1_2 - 0.00047 20.1 0.3 0.00064 19.7 0.3 1.2 1 0 0 1 1 1 1 T3SS negative regulator,GrlR AAA_21 PF13304.6 AAAP01003430.1_3 - 1.3e-07 31.8 0.5 3.7e-06 27.0 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003430.1_3 - 1.5e-07 31.1 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAAP01003430.1_3 - 0.0019 17.9 0.1 0.0025 17.6 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain BBP1_C PF15272.6 AAAP01003430.1_3 - 0.055 13.3 0.2 0.095 12.5 0.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF3732 PF12532.8 AAAP01003430.1_3 - 0.1 12.1 0.0 0.23 11.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3732) AAA_13 PF13166.6 AAAP01003430.1_3 - 0.15 10.7 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain OEP PF02321.18 AAAP01003431.1_1 - 5.9e-43 146.9 34.8 1.4e-22 80.4 17.3 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein HAGH_C PF16123.5 AAAP01003431.1_1 - 0.062 13.8 0.5 0.51 10.9 0.1 2.6 2 1 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Prok-TraM PF09228.10 AAAP01003431.1_1 - 0.1 13.0 1.4 0.38 11.1 1.4 2.0 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM ETF PF01012.21 AAAP01003432.1_1 - 1.2e-39 136.1 3.8 1.3e-39 136.0 3.8 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CoA_binding_2 PF13380.6 AAAP01003432.1_1 - 0.076 13.5 0.9 0.16 12.5 0.9 1.6 1 1 0 1 1 1 0 CoA binding domain Cob_adeno_trans PF01923.18 AAAP01003432.1_2 - 4.1e-60 202.6 0.0 4.7e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF3280 PF11684.8 AAAP01003433.1_1 - 1.8e-16 60.8 0.0 2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) adh_short_C2 PF13561.6 AAAP01003433.1_2 - 1e-55 188.9 0.0 1.3e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003433.1_2 - 4.3e-47 160.1 0.0 5.5e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003433.1_2 - 1.2e-06 28.6 0.0 1.6e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003433.1_2 - 0.066 12.7 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CCG PF02754.16 AAAP01003433.1_3 - 0.041 14.1 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich domain VWA_2 PF13519.6 AAAP01003434.1_1 - 1e-07 32.5 0.0 1.5e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3040 PF11239.8 AAAP01003434.1_2 - 0.089 13.1 1.4 0.47 10.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Tad PF13400.6 AAAP01003434.1_2 - 0.09 13.1 1.9 0.09 13.1 1.9 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like TPR_14 PF13428.6 AAAP01003434.1_2 - 2.3 9.3 19.1 1.7 9.7 0.6 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat VWA_2 PF13519.6 AAAP01003434.1_3 - 7.7e-10 39.4 0.0 1.3e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AAAP01003434.1_3 - 6e-05 23.4 0.0 8.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DEAD PF00270.29 AAAP01003435.1_2 - 1.1e-44 152.3 0.0 1.9e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAAP01003435.1_2 - 1.4e-27 96.2 0.0 5.9e-27 94.2 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAAP01003435.1_2 - 3.3e-05 24.0 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 AAAP01003435.1_2 - 0.0034 17.3 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 Helicase UTP25 PF06862.12 AAAP01003435.1_2 - 0.017 13.9 0.0 0.35 9.6 0.0 2.7 2 1 2 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF1508 PF07411.12 AAAP01003435.1_3 - 1.5e-16 60.0 0.1 1.7e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1508) Ubiq-assoc PF09145.10 AAAP01003435.1_4 - 2.5 8.2 4.0 23 5.1 0.5 2.3 2 0 0 2 2 2 0 Ubiquitin-associated HMA PF00403.26 AAAP01003436.1_2 - 3e-12 46.8 0.7 4.8e-12 46.1 0.7 1.3 1 1 0 1 1 1 1 Heavy-metal-associated domain MafB19-deam PF14437.6 AAAP01003436.1_2 - 0.039 13.7 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase GNAT_like PF18407.1 AAAP01003436.1_2 - 7.1 7.1 10.0 0.59 10.5 2.4 2.2 1 1 1 2 2 2 0 GCN5-related N-acetyltransferase like domain HMA PF00403.26 AAAP01003436.1_3 - 1.1e-27 96.3 0.2 6.9e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 Heavy-metal-associated domain FeS_assembly_P PF01883.19 AAAP01003436.1_3 - 0.039 14.1 1.3 3.7 7.8 0.1 2.8 2 1 0 2 2 2 0 Iron-sulfur cluster assembly protein Fer2_BFD PF04324.15 AAAP01003436.1_3 - 0.045 14.1 3.3 0.44 11.0 0.1 2.8 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain YscJ_FliF PF01514.17 AAAP01003436.1_3 - 0.12 12.1 0.1 11 5.7 0.0 2.3 2 1 0 2 2 2 0 Secretory protein of YscJ/FliF family Response_reg PF00072.24 AAAP01003437.1_1 - 1.7e-19 70.0 0.0 2e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF892 PF05974.12 AAAP01003437.1_3 - 2.1e-36 125.3 1.6 2.3e-36 125.2 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) DUF2383 PF09537.10 AAAP01003437.1_3 - 0.00088 19.6 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF3231 PF11553.8 AAAP01003437.1_3 - 0.033 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Ubiq_cyt_C_chap PF03981.12 AAAP01003437.1_3 - 0.039 14.0 0.2 0.087 12.9 0.2 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone EB1 PF03271.17 AAAP01003437.1_3 - 0.056 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif BRCT_2 PF16589.5 AAAP01003437.1_3 - 0.1 13.0 0.2 1.1 9.7 0.1 2.2 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF3597 PF12200.8 AAAP01003437.1_4 - 3.8e-51 173.0 0.2 6.3e-51 172.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) TDA11 PF17084.5 AAAP01003437.1_4 - 0.01 14.8 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 Bindin PF02084.15 AAAP01003437.1_4 - 0.06 13.6 1.6 0.076 13.3 1.6 1.2 1 0 0 1 1 1 0 Bindin PhaG_MnhG_YufB PF03334.14 AAAP01003438.1_1 - 1e-18 67.3 13.0 1.5e-18 66.8 13.0 1.3 1 0 0 1 1 1 1 Na+/H+ antiporter subunit MrpF_PhaF PF04066.13 AAAP01003438.1_2 - 4e-19 68.8 2.1 4e-19 68.8 2.1 1.9 2 0 0 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) TspO_MBR PF03073.15 AAAP01003438.1_2 - 0.03 14.4 2.1 0.035 14.2 2.1 1.1 1 0 0 1 1 1 0 TspO/MBR family DUF1656 PF07869.12 AAAP01003438.1_2 - 0.06 13.4 3.4 0.1 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) TraL PF07178.11 AAAP01003438.1_2 - 7.1 7.2 6.4 3.7 8.1 0.6 2.1 1 1 1 2 2 2 0 TraL protein MNHE PF01899.16 AAAP01003438.1_3 - 3e-37 127.6 0.8 3.4e-37 127.4 0.8 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit DIM PF08194.12 AAAP01003438.1_3 - 9.5 6.5 9.9 0.94 9.7 0.6 2.6 2 1 1 3 3 3 0 DIM protein Proton_antipo_M PF00361.20 AAAP01003438.1_4 - 3e-36 125.1 18.4 3e-36 125.1 18.4 2.1 2 2 0 2 2 2 1 Proton-conducting membrane transporter NADHdeh_related PF10125.9 AAAP01003438.1_4 - 7.9e-06 25.4 6.5 7.9e-06 25.4 6.5 3.3 2 1 1 3 3 3 1 NADH dehydrogenase I, subunit N related protein Proton_antipo_N PF00662.20 AAAP01003438.1_4 - 0.16 12.0 1.3 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 AAAP01003438.1_5 - 1.4e-23 82.5 0.7 1.7e-23 82.2 0.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CcmD PF04995.14 AAAP01003438.1_6 - 0.02 15.0 0.8 0.033 14.3 0.7 1.4 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) CbiA PF01656.23 AAAP01003439.1_2 - 0.055 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003439.1_2 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MCPVI PF02993.14 AAAP01003439.1_3 - 0.049 13.5 6.5 0.046 13.5 2.8 1.9 1 1 1 2 2 2 0 Minor capsid protein VI MerR-DNA-bind PF09278.11 AAAP01003439.1_3 - 0.052 14.1 0.8 0.052 14.1 0.8 1.9 2 0 0 2 2 2 0 MerR, DNA binding Equine_IAV_S2 PF06502.11 AAAP01003439.1_3 - 0.14 12.2 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein RHH_1 PF01402.21 AAAP01003439.1_4 - 0.096 12.7 0.3 0.096 12.7 0.3 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family TrwC PF08751.11 AAAP01003439.1_5 - 2.7e-16 59.9 0.1 3e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 TrwC relaxase DMT_YdcZ PF04657.13 AAAP01003440.1_1 - 4.3e-39 134.0 14.3 4.8e-39 133.8 14.3 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ DUF1270 PF06900.11 AAAP01003440.1_1 - 0.39 11.1 1.8 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) UPF0047 PF01894.17 AAAP01003440.1_2 - 2.2e-40 137.4 0.0 2.8e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DNA_ligase_A_M PF01068.21 AAAP01003440.1_3 - 2.7e-27 95.8 0.0 4.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 AAAP01003440.1_3 - 4.9e-12 46.3 0.1 1.1e-11 45.2 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region tRNA_Me_trans PF03054.16 AAAP01003441.1_1 - 9.8e-110 366.7 0.0 1.1e-109 366.5 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 AAAP01003441.1_1 - 8.6e-06 25.6 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AAAP01003441.1_1 - 0.00035 20.1 0.1 0.0011 18.6 0.1 1.8 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AAAP01003441.1_1 - 0.00089 18.4 0.1 0.0027 16.9 0.1 1.7 1 1 0 1 1 1 1 NAD synthase ThiI PF02568.14 AAAP01003441.1_1 - 0.0045 16.6 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) GP68 PF17469.2 AAAP01003441.1_1 - 0.0088 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Phage protein Gp68 Arginosuc_synth PF00764.19 AAAP01003441.1_1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 AAAP01003441.1_1 - 0.042 13.6 0.1 0.067 12.9 0.1 1.4 1 1 0 1 1 1 0 PP-loop family Methyltransf_25 PF13649.6 AAAP01003441.1_2 - 1.3e-06 29.0 0.0 2.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003441.1_2 - 1.1e-05 26.0 0.1 2.2e-05 25.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003441.1_2 - 0.0027 18.4 0.0 0.0041 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003441.1_2 - 0.0034 17.2 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003441.1_2 - 0.01 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003441.1_2 - 0.017 14.5 0.0 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AAAP01003441.1_2 - 0.044 13.5 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 AAAP01003441.1_2 - 0.053 12.8 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 AAAP01003441.1_2 - 0.085 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit EamA PF00892.20 AAAP01003442.1_1 - 7.8e-05 22.9 3.4 8.5e-05 22.8 3.4 1.1 1 0 0 1 1 1 1 EamA-like transporter family UPF0061 PF02696.14 AAAP01003442.1_2 - 4.3e-131 437.9 0.0 6e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family adh_short PF00106.25 AAAP01003442.1_3 - 1.8e-18 66.7 2.5 1.9e-18 66.6 2.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003442.1_3 - 3.5e-14 52.9 4.5 3.9e-14 52.8 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003442.1_3 - 5e-06 26.6 3.5 5.5e-06 26.4 3.5 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003442.1_3 - 0.00076 19.0 0.2 0.00083 18.9 0.2 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GATase_3 PF07685.14 AAAP01003443.1_1 - 2.5e-57 193.6 0.0 3e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.9 AAAP01003443.1_1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3616 PF12275.8 AAAP01003443.1_2 - 1.6e-17 63.9 0.0 1.5e-11 44.4 0.1 2.9 2 1 0 3 3 3 2 Protein of unknown function (DUF3616) Phytase-like PF13449.6 AAAP01003443.1_2 - 4.6e-06 26.8 0.0 7.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase Glycos_transf_1 PF00534.20 AAAP01003444.1_1 - 1.3e-28 99.7 0.0 2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003444.1_1 - 8.6e-28 97.5 1.7 8.6e-28 97.5 1.7 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AAAP01003444.1_1 - 1.4e-21 77.3 3.3 2.1e-21 76.8 0.7 2.4 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003444.1_1 - 1.6e-14 54.7 7.9 1.6e-14 54.7 7.9 2.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AAAP01003444.1_1 - 7.8e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 AAAP01003444.1_1 - 0.12 12.7 0.0 0.4 11.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 IF3_C PF00707.22 AAAP01003444.1_2 - 4.5e-39 132.3 2.5 6.7e-39 131.7 2.5 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AAAP01003444.1_2 - 4.8e-26 90.8 0.2 2e-25 88.8 0.0 2.0 2 1 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain AHSA1 PF08327.11 AAAP01003444.1_2 - 0.15 12.3 0.2 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein GDE_C PF06202.14 AAAP01003444.1_3 - 0.23 10.3 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase GARS_N PF02844.15 AAAP01003445.1_4 - 2.4e-15 57.1 0.0 2.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain DUF2125 PF09898.9 AAAP01003446.1_1 - 7.4e-64 216.4 12.9 8.7e-64 216.2 12.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2125) Gly-zipper_YMGG PF13441.6 AAAP01003446.1_1 - 0.0091 15.7 0.8 0.019 14.7 0.8 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AAAP01003446.1_1 - 0.013 15.5 1.5 0.024 14.6 1.5 1.4 1 0 0 1 1 1 0 Glycine zipper Glyco_tranf_2_4 PF13704.6 AAAP01003446.1_2 - 7.2e-13 48.9 0.0 1.4e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 AAAP01003446.1_2 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Lactate_perm PF02652.14 AAAP01003447.1_1 - 1.3e-70 238.6 28.3 1.6e-70 238.3 28.3 1.0 1 0 0 1 1 1 1 L-lactate permease NESP55 PF06390.12 AAAP01003447.1_1 - 0.12 11.9 4.2 0.2 11.2 4.2 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) SQS_PSY PF00494.19 AAAP01003447.1_2 - 9e-50 169.6 1.4 1e-49 169.4 1.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF498 PF04430.14 AAAP01003447.1_3 - 5.9e-33 113.2 0.0 6.8e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SecD_SecF PF02355.16 AAAP01003447.1_4 - 3.4e-50 170.0 14.5 3.8e-50 169.9 14.5 1.0 1 0 0 1 1 1 1 Protein export membrane protein ABC2_membrane PF01061.24 AAAP01003447.1_4 - 0.031 13.7 11.0 0.04 13.3 11.0 1.2 1 0 0 1 1 1 0 ABC-2 type transporter DAP_epimerase PF01678.19 AAAP01003448.1_1 - 1.1e-23 83.7 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Diaminopimelate epimerase Radical_SAM PF04055.21 AAAP01003448.1_2 - 1e-24 87.8 0.1 5.2e-24 85.5 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 AAAP01003448.1_2 - 2.6e-15 56.3 0.1 7e-15 54.9 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 PseudoU_synth_2 PF00849.22 AAAP01003448.1_3 - 9.5e-35 120.1 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_60s PF00428.19 AAAP01003449.1_1 - 0.0079 16.8 1.6 0.0095 16.5 0.0 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3682 PF12446.8 AAAP01003449.1_1 - 0.07 13.6 1.7 0.1 13.0 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF2937 PF11157.8 AAAP01003449.1_1 - 0.26 11.0 1.9 2 8.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) adh_short PF00106.25 AAAP01003450.1_2 - 8.4e-21 74.3 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003450.1_2 - 3.1e-20 72.8 0.2 3.8e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003450.1_2 - 0.00039 20.4 0.1 0.00058 19.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003450.1_2 - 0.0011 18.9 0.8 0.0017 18.3 0.8 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_trans_4_4 PF13579.6 AAAP01003450.1_2 - 0.0015 19.0 1.3 0.0039 17.7 1.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain NmrA PF05368.13 AAAP01003450.1_2 - 0.0015 18.1 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 AAAP01003450.1_2 - 0.0039 16.7 0.1 0.0055 16.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MgtC PF02308.16 AAAP01003450.1_3 - 3e-33 114.7 12.0 4.4e-33 114.2 12.0 1.2 1 0 0 1 1 1 1 MgtC family DUF1441 PF07278.11 AAAP01003450.1_3 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) AAA_3 PF07726.11 AAAP01003450.1_4 - 1.4e-59 199.6 0.0 2.3e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003450.1_4 - 7.8e-15 55.1 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 AAAP01003450.1_4 - 6.8e-14 51.5 2.4 6.8e-14 51.5 2.4 2.2 1 1 1 2 2 2 1 AAA lid domain MCM PF00493.23 AAAP01003450.1_4 - 3.9e-05 22.9 0.0 7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAAP01003450.1_4 - 0.00016 21.4 0.0 0.00099 18.8 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AAAP01003450.1_4 - 0.0032 16.9 0.6 0.49 9.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AAAP01003450.1_4 - 0.019 14.7 0.1 0.52 10.0 0.0 2.8 2 2 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DUF1707 PF08044.11 AAAP01003450.1_4 - 0.84 9.7 0.0 0.84 9.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) FTSW_RODA_SPOVE PF01098.19 AAAP01003451.1_1 - 1.3e-70 238.2 10.0 1.8e-70 237.7 10.0 1.1 1 0 0 1 1 1 1 Cell cycle protein Glyco_transf_28 PF03033.20 AAAP01003451.1_1 - 1.4e-26 93.2 0.3 2.1e-26 92.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain IMPDH PF00478.25 AAAP01003451.1_2 - 2.5e-96 322.7 8.4 3.1e-96 322.4 8.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AAAP01003451.1_2 - 1.5e-19 70.2 1.7 3e-11 43.6 0.0 2.9 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 AAAP01003451.1_2 - 1.5e-10 41.0 15.6 5.3e-06 26.0 10.3 2.5 1 1 2 3 3 3 2 Nitronate monooxygenase Radical_SAM PF04055.21 AAAP01003451.1_2 - 0.0016 18.8 0.0 0.044 14.2 0.0 2.8 1 1 0 1 1 1 1 Radical SAM superfamily FMN_dh PF01070.18 AAAP01003451.1_2 - 0.003 16.6 16.1 0.0041 16.2 11.3 2.2 1 1 1 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAAP01003451.1_2 - 0.0061 16.0 4.0 0.52 9.7 0.8 2.3 1 1 0 2 2 2 2 Histidine biosynthesis protein DeoC PF01791.9 AAAP01003451.1_2 - 0.014 15.0 5.0 0.028 14.0 4.0 2.0 1 1 0 1 1 1 0 DeoC/LacD family aldolase Methyltransf_20 PF12147.8 AAAP01003451.1_2 - 0.015 14.5 0.2 0.024 13.8 0.2 1.2 1 0 0 1 1 1 0 Putative methyltransferase CoA_binding_2 PF13380.6 AAAP01003451.1_2 - 0.016 15.7 0.3 0.061 13.8 0.3 2.0 2 0 0 2 2 2 0 CoA binding domain TMP-TENI PF02581.17 AAAP01003451.1_2 - 0.034 13.5 2.4 0.44 9.9 1.7 2.3 1 1 1 2 2 2 0 Thiamine monophosphate synthase NanE PF04131.14 AAAP01003451.1_2 - 0.04 13.1 3.6 0.28 10.4 3.4 2.5 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ComA PF02679.15 AAAP01003451.1_2 - 0.043 13.3 0.1 0.78 9.2 0.1 2.4 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) PGA_cap PF09587.10 AAAP01003451.1_2 - 0.099 12.1 0.4 6.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap DHO_dh PF01180.21 AAAP01003451.1_2 - 0.16 11.1 7.8 0.12 11.5 0.6 2.3 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase PcrB PF01884.17 AAAP01003451.1_2 - 0.64 9.4 3.1 1.4 8.4 1.2 2.6 2 1 1 3 3 3 0 PcrB family NicO PF03824.16 AAAP01003452.1_1 - 5.3e-17 62.1 5.2 6.3e-17 61.8 5.2 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF4131 PF13567.6 AAAP01003452.1_1 - 0.15 11.7 2.0 0.32 10.6 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1980 PF09323.10 AAAP01003452.1_1 - 0.28 11.1 0.1 0.46 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DsbD_2 PF13386.6 AAAP01003452.1_1 - 0.29 11.0 7.3 0.68 9.8 7.3 1.5 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region GT87 PF09594.10 AAAP01003452.1_1 - 0.56 9.9 13.7 0.6 9.8 1.3 2.3 1 1 1 2 2 2 0 Glycosyltransferase family 87 Metal_resist PF13801.6 AAAP01003452.1_1 - 1.3 9.2 5.3 0.59 10.3 1.1 2.4 2 2 0 2 2 2 0 Heavy-metal resistance Trns_repr_metal PF02583.17 AAAP01003452.1_2 - 2.6e-21 75.8 0.4 2.9e-21 75.6 0.4 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor DUF4765 PF15962.5 AAAP01003452.1_3 - 0.023 12.7 0.1 0.027 12.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) PCMT PF01135.19 AAAP01003453.1_1 - 2.8e-08 33.8 0.0 3.4e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glycos_transf_2 PF00535.26 AAAP01003453.1_2 - 1.4e-15 57.6 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003453.1_2 - 0.008 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HSP20 PF00011.21 AAAP01003454.1_3 - 4.3e-18 65.3 0.0 6.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01003454.1_3 - 0.00032 20.2 0.0 0.00082 18.9 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Glyco_tran_28_C PF04101.16 AAAP01003454.1_4 - 1.2e-05 25.3 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_2 PF00535.26 AAAP01003455.1_1 - 1.6e-14 54.0 0.0 3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_4 PF13439.6 AAAP01003455.1_1 - 3.4e-09 36.9 1.0 5.2e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_tranf_2_3 PF13641.6 AAAP01003455.1_1 - 1.5e-07 31.5 0.1 2.9e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AAAP01003455.1_1 - 0.0078 15.7 0.0 0.029 13.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AAAP01003455.1_1 - 0.043 13.3 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003455.1_1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family group 2 CysG_dimeriser PF10414.9 AAAP01003455.1_1 - 0.59 9.9 4.3 0.18 11.5 0.5 2.1 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region DUF21 PF01595.20 AAAP01003455.1_2 - 2e-33 115.6 7.6 2.3e-33 115.3 7.6 1.0 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain E1-E2_ATPase PF00122.20 AAAP01003455.1_2 - 0.032 13.8 0.3 0.06 12.9 0.1 1.6 1 1 0 1 1 1 0 E1-E2 ATPase Uma2 PF05685.12 AAAP01003456.1_2 - 1e-09 38.2 0.0 1.1e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Uma2 PF05685.12 AAAP01003456.1_4 - 7e-24 84.3 0.0 8.3e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease DUF1206 PF06724.11 AAAP01003456.1_6 - 4.7e-49 164.3 57.7 6.2e-18 64.7 15.2 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Tir_receptor_N PF07490.11 AAAP01003456.1_6 - 0.31 10.8 1.6 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus Bax1-I PF01027.20 AAAP01003457.1_1 - 6e-62 209.2 34.6 6.9e-62 209.0 34.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 YidD PF01809.18 AAAP01003457.1_2 - 3.9e-23 81.1 0.3 5.5e-23 80.6 0.3 1.2 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor NifU_N PF01592.16 AAAP01003457.1_3 - 1.5e-08 34.8 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain GTP_cyclohydroI PF01227.22 AAAP01003457.1_4 - 2.7e-16 59.5 0.0 2.8e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I DDE_Tnp_1 PF01609.21 AAAP01003458.1_1 - 3.1e-21 76.0 1.2 7.9e-21 74.7 1.2 1.6 1 1 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 AAAP01003458.1_1 - 2.2e-17 63.0 0.2 4.7e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AAAP01003458.1_1 - 2e-16 60.1 0.2 6.1e-16 58.6 0.1 1.8 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAAP01003458.1_1 - 8.1e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003458.1_1 - 0.0055 16.4 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 AAAP01003458.1_1 - 0.077 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.20 AAAP01003458.1_2 - 1.8e-19 69.8 0.1 2.8e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AAAP01003458.1_2 - 0.015 15.4 0.9 0.047 13.8 0.9 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003458.1_2 - 0.017 14.9 0.5 0.032 14.0 0.5 1.5 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.13 AAAP01003458.1_2 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HlyD_3 PF13437.6 AAAP01003459.1_1 - 3.8e-15 56.5 0.2 3e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003459.1_1 - 2e-12 46.8 1.4 2.6e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003459.1_1 - 8.1e-10 38.4 9.9 3.1e-08 33.3 0.1 4.1 5 0 0 5 5 5 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003459.1_1 - 4.7e-07 29.5 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AAAP01003459.1_1 - 0.0028 17.4 0.0 0.0098 15.6 0.0 1.8 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Spc7 PF08317.11 AAAP01003459.1_1 - 0.0044 15.9 4.7 0.0064 15.4 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 AAAP01003459.1_1 - 0.047 13.8 13.6 0.074 13.1 2.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 AAAP01003459.1_1 - 0.069 13.6 10.7 0.052 14.0 2.6 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HTH_18 PF12833.7 AAAP01003459.1_3 - 2.9e-16 59.5 0.3 5.9e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003459.1_3 - 2.3e-13 49.9 0.0 1.4e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Aminotran_3 PF00202.21 AAAP01003459.1_4 - 7.9e-35 120.3 0.0 9.3e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SAA PF00277.18 AAAP01003459.1_4 - 0.061 13.8 0.1 0.27 11.7 0.1 2.0 1 1 1 2 2 2 0 Serum amyloid A protein AraC_binding_2 PF14525.6 AAAP01003460.1_1 - 0.002 17.8 0.1 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 AraC-binding-like domain AraC_binding_2 PF14525.6 AAAP01003460.1_2 - 6.4e-28 97.6 1.6 6.4e-28 97.6 1.6 1.6 2 0 0 2 2 2 1 AraC-binding-like domain HTH_18 PF12833.7 AAAP01003460.1_2 - 1.6e-15 57.1 0.4 2.9e-15 56.3 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003460.1_2 - 0.0089 16.1 0.0 0.069 13.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family FMO-like PF00743.19 AAAP01003460.1_3 - 8.4e-40 136.7 0.0 1.6e-39 135.8 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 AAAP01003460.1_3 - 1.3e-19 70.6 0.0 2.6e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003460.1_3 - 6e-15 55.2 0.0 5.2e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003460.1_3 - 7.1e-11 42.2 0.1 7.8e-10 38.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003460.1_3 - 2.7e-09 37.1 0.5 1.3e-05 24.9 0.1 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAAP01003460.1_3 - 4.5e-07 30.3 0.1 3.1e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01003460.1_3 - 7.1e-06 26.1 0.6 0.15 12.0 0.0 3.3 2 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 AAAP01003460.1_3 - 8.6e-06 25.1 0.1 0.002 17.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AAAP01003460.1_3 - 2.7e-05 23.4 0.0 4.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 AAAP01003460.1_3 - 3.9e-05 23.1 0.1 0.0076 15.6 0.0 3.5 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 AAAP01003460.1_3 - 7.9e-05 22.2 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01003460.1_3 - 0.00089 18.1 0.4 0.002 16.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AAAP01003460.1_3 - 0.0047 16.3 0.1 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAAP01003460.1_3 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 AAAP01003460.1_3 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 AAAP01003460.1_3 - 0.022 13.8 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.12 AAAP01003460.1_3 - 0.055 13.0 0.4 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 AAAP01003460.1_3 - 0.068 12.2 0.1 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A AdoHcyase_NAD PF00670.21 AAAP01003460.1_3 - 0.084 12.9 0.5 9.8 6.2 0.0 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 AAAP01003460.1_3 - 0.1 13.0 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 AAAP01003460.1_3 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF364 PF04016.12 AAAP01003460.1_3 - 0.16 11.5 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Putative heavy-metal chelation UDPG_MGDP_dh_N PF03721.14 AAAP01003460.1_3 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 AAAP01003460.1_3 - 0.28 11.3 0.3 3.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_3 PF07859.13 AAAP01003460.1_4 - 1.4e-12 48.0 1.3 9.4e-12 45.2 1.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 AAAP01003460.1_4 - 0.0015 17.5 0.1 0.1 11.5 0.2 2.0 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 AAAP01003460.1_4 - 0.0032 17.0 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family YbgT_YccB PF08173.11 AAAP01003461.1_2 - 8.3e-15 54.6 8.6 9.4e-15 54.4 8.6 1.1 1 0 0 1 1 1 1 Membrane bound YbgT-like protein BatA PF07584.11 AAAP01003461.1_2 - 0.1 13.0 0.7 0.11 12.9 0.7 1.0 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Cyt_bd_oxida_II PF02322.15 AAAP01003461.1_3 - 1.6e-102 342.9 33.6 1.9e-102 342.7 33.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II NifT PF06988.11 AAAP01003461.1_3 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 NifT/FixU protein DUF4538 PF15061.6 AAAP01003461.1_3 - 0.83 9.4 4.3 1 9.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Cyt_bd_oxida_I PF01654.17 AAAP01003461.1_4 - 1.2e-108 363.4 13.1 1.5e-108 363.2 13.1 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF3099 PF11298.8 AAAP01003461.1_4 - 0.18 11.9 2.4 3 8.0 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) MFS_4 PF06779.14 AAAP01003462.1_1 - 2.2e-32 112.8 13.8 2.5e-32 112.6 13.8 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 AAAP01003462.1_1 - 0.0086 15.0 26.3 0.014 14.4 26.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.21 AAAP01003462.1_1 - 2.5 8.1 4.5 0.58 10.2 0.2 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif GIY-YIG PF01541.24 AAAP01003462.1_2 - 1.1e-09 38.4 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain LysE PF01810.18 AAAP01003462.1_3 - 4.6e-30 104.5 12.2 5.6e-30 104.2 12.2 1.1 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AAAP01003462.1_3 - 0.031 14.0 3.1 0.095 12.4 3.1 2.0 1 1 0 1 1 1 0 Integral membrane protein TerC family B277 PF17623.2 AAAP01003462.1_3 - 0.22 10.6 0.7 0.29 10.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function HATPase_c PF02518.26 AAAP01003462.1_4 - 2e-10 41.1 0.0 2.2e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CobT PF06213.12 AAAP01003463.1_2 - 1.2e-12 47.8 0.0 1.4e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CobS_N PF12556.8 AAAP01003463.1_3 - 3.2e-19 68.3 0.4 6.2e-19 67.4 0.4 1.5 1 0 0 1 1 1 1 Cobaltochelatase CobS subunit N terminal AAA_5 PF07728.14 AAAP01003463.1_3 - 5.5e-11 42.6 0.0 9.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 AAAP01003463.1_3 - 3.8e-05 23.9 0.0 6.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA PF00004.29 AAAP01003463.1_3 - 0.00022 21.6 0.0 0.001 19.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAAP01003463.1_3 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003463.1_3 - 0.0012 19.0 0.0 0.0035 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003463.1_3 - 0.0056 17.1 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 AAAP01003463.1_3 - 0.0065 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AAAP01003463.1_3 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAAP01003463.1_3 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAAP01003463.1_3 - 0.019 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 AAAP01003463.1_3 - 0.021 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 AAAP01003463.1_3 - 0.09 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase PF06745.13 AAAP01003463.1_3 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 AAAP01003463.1_3 - 0.15 12.6 0.0 0.3 11.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 AAAP01003463.1_3 - 0.19 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DnaJ PF00226.31 AAAP01003463.1_4 - 9.6e-10 38.5 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pterin_bind PF00809.22 AAAP01003464.1_1 - 8.2e-06 25.7 0.0 2.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Pterin binding enzyme AA_kinase PF00696.28 AAAP01003464.1_2 - 1.7e-10 40.9 0.3 2.3e-06 27.4 0.1 2.1 1 1 1 2 2 2 2 Amino acid kinase family YAcAr PF10686.9 AAAP01003464.1_2 - 0.033 14.1 0.4 0.23 11.4 0.1 2.3 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family Axin_b-cat_bind PF08833.10 AAAP01003464.1_2 - 0.15 12.2 0.0 0.78 9.9 0.0 2.0 2 0 0 2 2 2 0 Axin beta-catenin binding domain 4HFCP_synth PF04476.13 AAAP01003464.1_3 - 7.8e-53 179.5 2.6 9.5e-53 179.2 2.6 1.1 1 0 0 1 1 1 1 4-HFC-P synthase DUF3280 PF11684.8 AAAP01003464.1_4 - 6.8e-42 143.1 0.0 7.9e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) Peripla_BP_6 PF13458.6 AAAP01003465.1_1 - 1.7e-06 27.9 0.1 2.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HTH_Tnp_Mu_1 PF02316.16 AAAP01003465.1_1 - 0.0086 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Mu DNA-binding domain PAS PF00989.25 AAAP01003465.1_2 - 2.6e-29 101.5 0.0 1.9e-14 53.6 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01003465.1_2 - 2.8e-28 98.2 0.0 2e-15 56.9 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 AAAP01003465.1_2 - 2.3e-25 89.0 0.2 1.7e-09 37.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AAAP01003465.1_2 - 2.4e-24 84.8 0.1 1.1e-08 34.9 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 AAAP01003465.1_2 - 2.8e-10 40.3 0.2 5.9e-08 32.9 0.1 3.2 3 0 0 3 3 3 1 PAS fold HAMP PF00672.25 AAAP01003465.1_2 - 1.6e-05 25.1 0.2 8e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 HAMP domain dCache_1 PF02743.18 AAAP01003465.1_2 - 0.004 17.0 1.3 0.021 14.6 0.1 2.4 2 1 0 2 2 2 1 Cache domain Cep57_MT_bd PF06657.13 AAAP01003465.1_2 - 0.11 13.0 0.4 0.33 11.4 0.4 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Polysacc_deac_1 PF01522.21 AAAP01003466.1_2 - 1.3e-09 38.0 0.0 2.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase TarH PF02203.15 AAAP01003466.1_2 - 0.029 14.3 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue GAGA_bind PF06217.12 AAAP01003466.1_2 - 0.19 12.0 0.1 0.34 11.1 0.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Fer2_2 PF01799.20 AAAP01003466.1_3 - 2.5e-23 81.9 0.5 2.5e-23 81.9 0.5 1.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003466.1_3 - 0.0001 22.2 0.8 0.0001 22.2 0.8 1.8 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01003466.1_3 - 0.00048 20.1 0.4 0.00048 20.1 0.4 1.4 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ald_Xan_dh_C2 PF02738.18 AAAP01003466.1_4 - 5.4e-16 58.2 0.5 6.4e-16 57.9 0.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Polysacc_synt_2 PF02719.15 AAAP01003467.1_2 - 2.5e-98 328.8 0.1 3.4e-98 328.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAAP01003467.1_2 - 2.1e-19 70.0 0.2 1.6e-18 67.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003467.1_2 - 1.1e-11 44.4 0.1 3.6e-11 42.7 0.0 1.8 2 1 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAAP01003467.1_2 - 4.9e-09 36.0 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003467.1_2 - 1.8e-06 27.2 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AAAP01003467.1_2 - 2.5e-06 27.1 0.2 6.8e-06 25.7 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003467.1_2 - 5.3e-05 23.2 0.1 0.00016 21.6 0.1 1.9 1 0 0 1 1 1 1 KR domain OPT PF03169.15 AAAP01003468.1_1 - 6.9e-39 134.0 9.9 7.7e-39 133.8 9.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF983 PF06170.12 AAAP01003468.1_1 - 0.083 13.3 7.0 1.3 9.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF1989 PF09347.10 AAAP01003468.1_2 - 1.2e-54 184.5 0.0 1.4e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) YqcI_YcgG PF08892.11 AAAP01003468.1_3 - 2.2e-51 174.7 0.0 2.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 YqcI/YcgG family PAS PF00989.25 AAAP01003469.1_1 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003469.1_1 - 0.0024 18.1 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003469.1_1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAAP01003469.1_1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 PAS domain Pyr_redox_2 PF07992.14 AAAP01003469.1_2 - 5.6e-32 111.1 0.2 1.3e-31 110.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003469.1_2 - 1.6e-10 40.6 5.3 4e-07 29.5 0.3 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox PF00070.27 AAAP01003469.1_2 - 5.5e-10 39.7 3.7 1.6e-08 35.0 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003469.1_2 - 6.4e-06 25.6 5.0 0.027 13.8 3.3 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AAAP01003469.1_2 - 7.3e-06 26.1 5.3 0.0069 16.6 0.1 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAAP01003469.1_2 - 5.5e-05 22.7 7.7 0.00078 18.9 4.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01003469.1_2 - 0.00026 19.8 6.6 0.06 12.0 2.7 2.5 2 0 0 2 2 2 2 HI0933-like protein 3HCDH_N PF02737.18 AAAP01003469.1_2 - 0.00029 20.8 1.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 AAAP01003469.1_2 - 0.00029 21.3 0.3 0.0078 16.7 0.0 2.4 2 1 0 2 2 2 1 XdhC Rossmann domain FAD_binding_3 PF01494.19 AAAP01003469.1_2 - 0.001 18.4 6.0 0.11 11.8 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 AAAP01003469.1_2 - 0.0015 17.8 1.0 0.24 10.6 0.3 2.3 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 AAAP01003469.1_2 - 0.0021 17.2 5.5 0.35 9.9 1.3 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AAAP01003469.1_2 - 0.0024 17.2 3.3 1.3 8.2 2.4 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01003469.1_2 - 0.0056 15.8 8.7 0.02 14.0 5.8 2.2 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 AAAP01003469.1_2 - 0.0089 15.2 1.0 0.032 13.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AAAP01003469.1_2 - 0.012 15.3 0.4 0.012 15.3 0.4 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 AAAP01003469.1_2 - 0.13 11.6 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 AAAP01003469.1_2 - 0.18 11.1 1.3 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 ThiF family adh_short_C2 PF13561.6 AAAP01003469.1_3 - 2.8e-49 167.8 0.2 5.9e-49 166.7 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003469.1_3 - 1.4e-36 125.8 0.0 1.9e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase HTH_31 PF13560.6 AAAP01003470.1_1 - 1.6e-05 25.2 0.1 2.6e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAAP01003470.1_1 - 1.6e-05 24.6 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 AAAP01003470.1_1 - 0.00015 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003470.1_1 - 0.025 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_transf PF02397.16 AAAP01003471.1_1 - 4.5e-56 189.4 0.0 6.6e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AAAP01003471.1_1 - 0.054 13.5 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 CoA-binding domain CbiA PF01656.23 AAAP01003471.1_2 - 4.3e-08 33.3 0.0 4.7e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAAP01003471.1_2 - 0.00025 20.4 0.6 0.00054 19.3 0.1 1.8 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 AAAP01003471.1_2 - 0.0003 20.8 0.0 0.42 10.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain APS_kinase PF01583.20 AAAP01003471.1_2 - 0.00067 19.6 0.1 0.0054 16.6 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase ParA PF10609.9 AAAP01003471.1_2 - 0.00086 18.8 0.3 0.009 15.5 0.1 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Glyco_trans_4_4 PF13579.6 AAAP01003471.1_2 - 0.0072 16.8 8.9 0.0072 16.8 8.9 3.0 3 1 1 4 4 4 1 Glycosyl transferase 4-like domain CBP_BcsQ PF06564.12 AAAP01003471.1_2 - 0.1 12.1 0.9 7.5 6.0 0.1 2.8 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsQ DUF4201 PF13870.6 AAAP01003471.1_2 - 1.4 8.6 5.6 8.5 6.1 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 AAAP01003471.1_2 - 2.2 7.1 9.0 2 7.2 3.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Glyco_trans_1_2 PF13524.6 AAAP01003471.1_3 - 0.0061 16.9 0.4 0.018 15.4 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF678 PF05077.12 AAAP01003471.1_3 - 2.7 8.2 3.9 4.8 7.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF678) DDE_Tnp_1_2 PF13586.6 AAAP01003472.1_2 - 2.6e-13 50.1 0.2 3.1e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01003472.1_2 - 7.7e-06 25.7 0.1 8e-06 25.7 0.1 1.0 1 0 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 AAAP01003472.1_3 - 6.5e-21 74.3 1.0 1.3e-20 73.4 1.0 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAAP01003472.1_3 - 5.3e-11 42.6 0.0 7.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAAP01003472.1_3 - 4.8e-06 26.6 0.0 7.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 AAAP01003472.1_4 - 2.6e-22 78.8 0.8 5.2e-22 77.8 0.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AAAP01003472.1_4 - 2.8e-21 76.2 1.1 7.1e-21 74.8 1.1 1.6 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAAP01003472.1_4 - 1.1e-16 61.0 0.2 5.9e-16 58.6 0.1 2.1 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AAAP01003472.1_4 - 7.8e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003472.1_4 - 0.005 16.5 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 AAAP01003472.1_4 - 0.074 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HD_5 PF13487.6 AAAP01003473.1_1 - 4.7e-13 49.2 0.0 6.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003473.1_1 - 0.00058 20.1 0.0 0.00078 19.7 0.0 1.2 1 0 0 1 1 1 1 HD domain GAF PF01590.26 AAAP01003473.1_2 - 7.8e-13 49.2 0.0 1.1e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAAP01003473.1_2 - 4.8e-10 39.9 0.1 7.9e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAAP01003473.1_2 - 0.0014 19.0 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 GAF domain DUF1178 PF06676.11 AAAP01003474.1_1 - 3e-27 95.8 0.1 3.4e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) CNTF PF01110.17 AAAP01003474.1_1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Ciliary neurotrophic factor PAS_9 PF13426.7 AAAP01003474.1_2 - 1.2e-21 76.9 0.0 2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 PAS domain HisKA_2 PF07568.12 AAAP01003474.1_2 - 3.6e-12 46.2 0.0 6.5e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase PAS PF00989.25 AAAP01003474.1_2 - 8.9e-10 38.6 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003474.1_2 - 1.4e-07 31.7 0.0 4.7e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003474.1_2 - 2.3e-06 27.8 0.0 4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AAAP01003474.1_2 - 2e-05 25.1 0.0 0.0028 18.1 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AAAP01003474.1_2 - 3.6e-05 23.7 0.0 8.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAAP01003474.1_2 - 0.00027 20.9 0.1 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HWE_HK PF07536.14 AAAP01003474.1_2 - 0.012 16.3 0.0 0.027 15.2 0.0 1.7 1 0 0 1 1 1 0 HWE histidine kinase PMSR PF01625.21 AAAP01003474.1_3 - 4.4e-63 212.1 0.1 5.1e-63 211.8 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Phage_fiber_2 PF03406.13 AAAP01003474.1_3 - 0.029 13.9 1.0 0.042 13.4 1.0 1.2 1 0 0 1 1 1 0 Phage tail fibre repeat UPF0114 PF03350.16 AAAP01003474.1_4 - 2.4e-06 27.7 0.7 2.6e-06 27.6 0.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein family, UPF0114 DHQ_synthase PF01761.20 AAAP01003474.1_4 - 0.14 11.3 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase AA_permease_2 PF13520.6 AAAP01003475.1_1 - 1.4e-09 37.3 18.0 1.6e-09 37.1 18.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AAAP01003475.1_1 - 8e-06 24.7 15.6 1e-05 24.4 15.6 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 AAAP01003475.1_1 - 0.032 13.0 6.7 0.043 12.5 6.7 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein DUF4392 PF14336.6 AAAP01003475.1_2 - 0.16 11.4 0.2 0.14 11.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF2207 PF09972.9 AAAP01003475.1_3 - 0.098 11.4 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4293 PF14126.6 AAAP01003475.1_3 - 0.19 12.0 1.8 0.57 10.4 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) HemY_N PF07219.13 AAAP01003475.1_3 - 2.1 8.6 4.1 24 5.2 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF4173 PF13777.6 AAAP01003475.1_4 - 0.0064 15.9 2.7 0.0081 15.6 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4173) TMEM100 PF16311.5 AAAP01003475.1_4 - 0.081 12.5 1.0 0.11 12.1 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 DUF2964 PF11177.8 AAAP01003475.1_4 - 1 9.6 5.2 0.48 10.7 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2964) LRR_8 PF13855.6 AAAP01003475.1_5 - 3.5e-16 58.7 0.2 6.3e-10 38.7 0.3 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 AAAP01003475.1_5 - 4.7e-12 45.9 0.1 0.00026 21.3 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 AAAP01003475.1_5 - 3.4e-06 26.8 4.5 5.6 7.9 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 AAAP01003475.1_5 - 0.0015 18.0 0.0 0.01 15.4 0.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 AAAP01003475.1_5 - 0.079 13.0 0.0 4.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat PHY PF00360.20 AAAP01003476.1_1 - 1e-36 126.0 0.3 1.7e-36 125.2 0.3 1.3 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 AAAP01003476.1_1 - 9.9e-16 58.6 0.0 2.5e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 AAAP01003476.1_1 - 2.2e-10 41.2 0.0 7.4e-09 36.2 0.0 2.6 2 1 0 2 2 2 1 PAS fold rve PF00665.26 AAAP01003476.1_2 - 2.3e-13 50.4 0.0 2.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01003476.1_2 - 5.2e-12 45.4 0.0 7.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01003476.1_2 - 0.094 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DUF1330 PF07045.11 AAAP01003477.1_1 - 4.1e-13 49.5 0.0 4.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) TetR_C_27 PF17935.1 AAAP01003477.1_2 - 1.8e-25 89.0 1.3 2.3e-25 88.7 0.4 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAAP01003477.1_2 - 4.3e-12 45.6 0.1 7.6e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAAP01003477.1_2 - 3.7e-06 27.2 0.6 1.1e-05 25.7 0.3 1.8 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AAAP01003477.1_2 - 0.0052 16.8 0.3 0.11 12.5 0.0 2.4 1 1 1 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain HTH_AsnC-type PF13404.6 AAAP01003477.1_2 - 0.021 14.7 0.2 2.4 8.1 0.0 3.3 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAAP01003477.1_2 - 0.035 14.0 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 MarR family DUF1643 PF07799.12 AAAP01003477.1_2 - 0.063 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) HTH_5 PF01022.20 AAAP01003477.1_2 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family ApbA_C PF08546.11 AAAP01003477.1_2 - 0.13 12.5 0.5 0.42 10.8 0.1 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF3791 PF12668.7 AAAP01003477.1_2 - 0.23 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF3363 PF11843.8 AAAP01003477.1_2 - 0.24 10.3 1.4 1.4 7.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3363) dUTPase PF00692.19 AAAP01003477.1_4 - 1.5e-21 76.4 0.0 1.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF429 PF04250.13 AAAP01003477.1_5 - 1e-52 179.0 4.6 1.2e-52 178.8 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF429) NUDIX PF00293.28 AAAP01003477.1_6 - 0.0024 17.9 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Peptidase_M23 PF01551.22 AAAP01003478.1_1 - 8.1e-32 109.3 0.7 1.5e-31 108.5 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M23 DUF815 PF05673.13 AAAP01003478.1_2 - 5e-101 337.1 0.0 5.7e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 AAAP01003478.1_2 - 2.3e-07 31.3 1.7 8e-05 23.1 0.0 3.4 3 1 1 4 4 4 1 AAA ATPase domain AAA PF00004.29 AAAP01003478.1_2 - 0.0038 17.7 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAAP01003478.1_2 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003478.1_2 - 0.11 12.4 0.0 7.3 6.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_29 PF13555.6 AAAP01003478.1_2 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003478.1_2 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Bac_DnaA PF00308.18 AAAP01003478.1_2 - 0.19 11.5 0.0 0.66 9.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein YajC PF02699.15 AAAP01003478.1_3 - 6.6e-28 96.4 0.5 7.8e-28 96.2 0.5 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit MreC PF04085.14 AAAP01003478.1_3 - 0.00014 21.8 2.1 0.00018 21.4 2.1 1.1 1 0 0 1 1 1 1 rod shape-determining protein MreC Orf78 PF06024.12 AAAP01003478.1_3 - 0.0022 18.3 0.4 0.0034 17.6 0.4 1.2 1 0 0 1 1 1 1 Orf78 (ac78) T2SSM PF04612.12 AAAP01003478.1_3 - 0.033 14.3 0.0 0.053 13.6 0.0 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Sec_GG PF07549.14 AAAP01003478.1_4 - 1.4e-06 27.6 0.4 5.1e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 SecD/SecF GG Motif EPSP_synthase PF00275.20 AAAP01003479.1_1 - 2.6e-94 316.3 0.0 2.9e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) RsgA_GTPase PF03193.16 AAAP01003479.1_2 - 1.4e-42 145.4 0.0 2.4e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003479.1_2 - 3.7e-08 33.4 0.0 7.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AAAP01003479.1_2 - 3.5e-05 24.2 1.3 7.6e-05 23.2 0.2 2.1 2 2 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 AAAP01003479.1_2 - 0.00025 21.5 0.0 0.00049 20.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01003479.1_2 - 0.0012 18.5 0.1 0.0037 17.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 AAAP01003479.1_2 - 0.01 15.4 1.1 0.79 9.2 0.1 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 AAAP01003479.1_2 - 0.012 15.4 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain TPR_9 PF13371.6 AAAP01003479.1_2 - 0.014 15.5 1.3 0.059 13.5 1.3 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat AAA_33 PF13671.6 AAAP01003479.1_2 - 0.021 15.0 0.2 0.086 13.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 AAAP01003479.1_2 - 0.049 13.0 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AIG1 family AAA_25 PF13481.6 AAAP01003479.1_2 - 0.059 12.9 1.7 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 AAAP01003479.1_2 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin NACHT PF05729.12 AAAP01003479.1_2 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 AAAP01003479.1_2 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BHD_3 PF10405.9 AAAP01003479.1_2 - 0.15 12.5 0.0 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 Dynamin_N PF00350.23 AAAP01003479.1_2 - 0.16 12.0 0.1 0.99 9.4 0.0 2.0 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 AAAP01003479.1_2 - 0.17 12.3 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 AAAP01003479.1_2 - 0.23 11.0 0.1 0.64 9.5 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Acyl-CoA_dh_1 PF00441.24 AAAP01003480.1_1 - 4e-27 95.3 4.1 9e-27 94.1 4.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003480.1_1 - 2e-18 66.4 0.0 4.3e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAAP01003480.1_1 - 1.3e-10 41.9 0.0 2.8e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01003480.1_1 - 9.6e-08 32.4 2.0 2.1e-07 31.3 2.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 AAAP01003480.1_1 - 6.7e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Sua5_yciO_yrdC PF01300.18 AAAP01003480.1_2 - 6.2e-50 169.2 0.0 8e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 AAAP01003480.1_2 - 2.2e-21 76.8 0.1 4.5e-21 75.8 0.1 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding HTH_28 PF13518.6 AAAP01003480.1_2 - 0.67 10.1 2.8 30 4.8 0.3 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain Phage_pRha PF09669.10 AAAP01003481.1_1 - 0.06 13.9 0.0 0.075 13.6 0.0 1.2 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Tli4_C PF18426.1 AAAP01003481.1_1 - 0.16 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Pro_isomerase PF00160.21 AAAP01003481.1_3 - 1.7e-44 151.9 0.0 2e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 AAAP01003481.1_4 - 1.6e-22 80.4 0.0 1.7e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD He_PIG PF05345.12 AAAP01003482.1_1 - 1.1e-05 25.5 4.1 1.1e-05 25.5 4.1 6.3 5 2 1 6 6 6 1 Putative Ig domain DUF824 PF05688.11 AAAP01003482.1_1 - 0.038 13.8 1.8 3.9 7.4 0.1 3.2 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) FAD_binding_3 PF01494.19 AAAP01003483.1_1 - 8.5e-06 25.2 0.3 9.3e-06 25.1 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003483.1_1 - 0.0012 19.1 0.2 0.0014 18.8 0.2 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003483.1_1 - 0.0053 16.4 0.2 0.0061 16.2 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 AAAP01003483.1_2 - 1.3e-108 363.6 0.0 1.6e-108 363.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01003483.1_2 - 1e-05 25.1 0.4 1.5e-05 24.6 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003483.1_2 - 1.5e-05 24.3 0.8 2.8e-05 23.4 0.6 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003483.1_2 - 7.8e-05 22.8 1.2 0.00058 20.0 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003483.1_2 - 0.00067 19.3 0.5 0.0013 18.4 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003483.1_2 - 0.0077 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003483.1_2 - 0.044 13.1 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase_2 PF02350.19 AAAP01003483.1_3 - 1.2e-85 287.4 0.0 1.4e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 AAAP01003483.1_3 - 0.00024 21.6 0.1 0.0035 17.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.20 AAAP01003483.1_3 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Polysacc_synt_2 PF02719.15 AAAP01003483.1_4 - 2.3e-84 283.0 0.1 2.7e-84 282.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_syn_2C PF08485.10 AAAP01003483.1_4 - 1.6e-22 79.0 1.0 3.1e-22 78.0 1.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein C-terminal Epimerase PF01370.21 AAAP01003483.1_4 - 5e-15 55.6 0.2 1.6e-13 50.7 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003483.1_4 - 9.4e-07 28.5 0.0 5.8e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003483.1_4 - 5.1e-06 25.7 0.1 1.1e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003483.1_4 - 0.00098 18.3 0.2 0.0059 15.7 0.1 2.2 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAAP01003483.1_4 - 0.019 14.1 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.6 AAAP01003483.1_4 - 0.12 12.2 0.1 0.44 10.4 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H-binding PepSY PF03413.19 AAAP01003484.1_1 - 0.0018 18.8 0.0 0.0019 18.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Trans_reg_C PF00486.28 AAAP01003484.1_2 - 1.6e-24 85.8 0.3 4.9e-24 84.2 0.2 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01003484.1_2 - 1.7e-24 86.1 0.0 2.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Rrf2 PF02082.20 AAAP01003484.1_2 - 0.13 12.6 0.0 3.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Transcriptional regulator PSK_trans_fac PF07704.11 AAAP01003484.1_3 - 0.06 14.1 0.0 0.066 14.0 0.0 1.1 1 0 0 1 1 1 0 Rv0623-like transcription factor HATPase_c PF02518.26 AAAP01003484.1_4 - 1.2e-06 29.0 0.0 2.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003484.1_4 - 0.0014 18.6 0.1 0.0056 16.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain 2CSK_N PF08521.10 AAAP01003484.1_4 - 0.012 15.7 2.4 0.31 11.1 1.2 2.9 2 1 0 2 2 2 0 Two-component sensor kinase N-terminal HAMP PF00672.25 AAAP01003484.1_4 - 0.024 15.0 0.9 0.13 12.6 0.9 2.4 1 1 0 1 1 1 0 HAMP domain HATPase_c_3 PF13589.6 AAAP01003484.1_4 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SIKE PF05769.11 AAAP01003484.1_4 - 0.22 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 SIKE family DUF5480 PF17576.2 AAAP01003484.1_4 - 0.43 10.6 2.4 0.33 10.9 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5480) DUF3126 PF11324.8 AAAP01003485.1_1 - 1.3e-26 92.1 0.5 1.5e-26 91.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3126) SATase_N PF06426.14 AAAP01003485.1_3 - 6.5e-36 122.9 0.0 9.2e-36 122.4 0.0 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 AAAP01003485.1_3 - 9e-10 37.9 5.7 2.7e-06 26.9 0.9 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SKI PF01202.22 AAAP01003485.1_4 - 8.1e-33 113.8 0.0 1.3e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase HTH_31 PF13560.6 AAAP01003485.1_4 - 3.4e-09 36.9 2.6 3.4e-09 36.9 2.6 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003485.1_4 - 8.4e-09 35.4 0.1 1.9e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix AAA_18 PF13238.6 AAAP01003485.1_4 - 4.1e-07 30.6 0.0 1.2e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain HTH_19 PF12844.7 AAAP01003485.1_4 - 0.00019 21.4 0.1 0.00049 20.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_33 PF13671.6 AAAP01003485.1_4 - 0.00036 20.7 0.1 0.0031 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain HTH_25 PF13413.6 AAAP01003485.1_4 - 0.0084 15.9 0.1 0.026 14.4 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain AAA PF00004.29 AAAP01003485.1_4 - 0.0088 16.5 0.0 0.058 13.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HTH_26 PF13443.6 AAAP01003485.1_4 - 0.03 14.8 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain ABC_tran PF00005.27 AAAP01003485.1_4 - 0.033 14.7 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.6 AAAP01003485.1_4 - 0.042 14.0 0.1 3 8.0 0.0 2.8 2 1 1 3 3 3 0 Cytidylate kinase-like family AAA_16 PF13191.6 AAAP01003485.1_4 - 0.071 13.5 0.7 0.2 12.0 0.2 1.9 1 1 1 2 2 2 0 AAA ATPase domain Cytidylate_kin PF02224.18 AAAP01003485.1_4 - 0.076 12.7 0.1 1.7 8.3 0.0 2.5 2 1 0 2 2 2 0 Cytidylate kinase HTH_37 PF13744.6 AAAP01003485.1_4 - 0.077 13.0 0.2 0.24 11.4 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_14 PF13173.6 AAAP01003485.1_4 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 AAAP01003485.1_4 - 0.18 11.1 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 HTH_Crp_2 PF13545.6 AAAP01003485.1_5 - 2.8e-11 43.2 1.5 6.4e-11 42.1 1.5 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003485.1_5 - 0.088 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pyr_redox_2 PF07992.14 AAAP01003486.1_1 - 7.1e-27 94.4 0.0 1.4e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003486.1_1 - 2.9e-13 49.7 0.0 8.9e-08 31.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003486.1_1 - 1.2e-08 35.0 1.3 5.1e-06 26.3 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003486.1_1 - 2.7e-08 33.3 0.0 1.1e-05 24.8 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 AAAP01003486.1_1 - 1.5e-06 27.5 2.8 0.0002 20.5 0.1 3.4 2 2 2 4 4 4 1 Lycopene cyclase protein HI0933_like PF03486.14 AAAP01003486.1_1 - 2.5e-06 26.5 0.0 2.7e-05 23.1 0.1 2.2 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 AAAP01003486.1_1 - 1.6e-05 25.3 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003486.1_1 - 1.7e-05 24.1 0.3 0.0023 17.1 0.1 3.2 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AAAP01003486.1_1 - 0.00021 20.7 0.1 0.00036 19.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 AAAP01003486.1_1 - 0.00052 20.0 0.8 0.14 12.2 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AAAP01003486.1_1 - 0.00066 19.9 0.1 0.0018 18.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAAP01003486.1_1 - 0.00077 18.9 0.1 0.00077 18.9 0.1 1.5 2 0 0 2 2 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAAP01003486.1_1 - 0.0018 17.6 0.1 0.0058 15.9 0.1 1.7 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 AAAP01003486.1_1 - 0.0099 15.1 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 AAAP01003486.1_1 - 0.14 11.0 0.2 0.21 10.4 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SGL PF08450.12 AAAP01003486.1_2 - 6.8e-61 206.0 0.0 7.9e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 AAAP01003486.1_2 - 0.0051 16.7 1.8 0.84 9.7 0.0 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Phytase-like PF13449.6 AAAP01003486.1_2 - 0.008 16.1 0.0 0.063 13.2 0.0 2.2 2 1 0 2 2 2 1 Esterase-like activity of phytase DUF839 PF05787.13 AAAP01003486.1_2 - 0.028 13.6 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.11 AAAP01003486.1_2 - 0.15 12.4 0.7 12 6.6 0.1 3.2 3 0 0 3 3 3 0 Two component regulator propeller Proteasome_A_N PF10584.9 AAAP01003486.1_2 - 0.17 11.6 6.9 12 5.7 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature GGDEF PF00990.21 AAAP01003487.1_1 - 3.4e-33 114.7 0.0 7e-33 113.7 0.0 1.5 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain YjgF_endoribonc PF14588.6 AAAP01003487.1_2 - 1.1e-41 142.4 0.1 1.2e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 AAAP01003487.1_2 - 8.6e-24 83.9 0.0 1.1e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1127 PF06568.11 AAAP01003487.1_3 - 9.3e-07 28.5 0.7 1.4e-06 28.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) Thioredoxin PF00085.20 AAAP01003487.1_4 - 0.00045 20.2 0.0 0.0085 16.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 AAAP01003487.1_4 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 AAAP01003487.1_4 - 0.049 14.0 0.0 0.073 13.4 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like T4_deiodinase PF00837.17 AAAP01003487.1_4 - 0.15 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase SecY PF00344.20 AAAP01003488.1_1 - 4.6e-27 95.1 1.9 9.6e-26 90.7 0.8 2.0 2 0 0 2 2 2 2 SecY translocase SecY PF00344.20 AAAP01003488.1_2 - 7.3e-79 265.2 7.6 8.3e-79 265.0 7.6 1.0 1 0 0 1 1 1 1 SecY translocase ADK PF00406.22 AAAP01003488.1_3 - 9.7e-56 188.1 0.0 1.2e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AAAP01003488.1_3 - 4e-27 95.3 0.1 5.2e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003488.1_3 - 1e-08 35.4 0.0 1.4e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAAP01003488.1_3 - 2.2e-05 25.0 0.0 3.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 AAAP01003488.1_3 - 0.0005 20.4 0.1 0.65 10.2 0.0 2.5 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 AAAP01003488.1_3 - 0.027 14.2 0.1 0.044 13.5 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 AAAP01003488.1_3 - 0.11 11.8 0.1 12 5.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Ribosomal_S13 PF00416.22 AAAP01003488.1_4 - 4.2e-31 108.0 6.3 1.1e-29 103.4 6.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AAAP01003488.1_4 - 0.034 12.9 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH PF00633.23 AAAP01003488.1_4 - 0.043 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_6 PF14579.6 AAAP01003488.1_4 - 0.057 13.7 0.3 0.39 11.0 0.3 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix motif HHH_3 PF12836.7 AAAP01003488.1_4 - 0.078 13.2 0.1 0.25 11.6 0.0 2.0 1 1 1 2 2 2 0 Helix-hairpin-helix motif HHH_7 PF14635.6 AAAP01003488.1_4 - 0.13 12.7 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 AAAP01003488.1_4 - 0.14 12.0 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Ribosomal_S11 PF00411.19 AAAP01003488.1_5 - 1.3e-49 167.1 1.5 1.6e-49 166.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 3HCDH_RFF PF18321.1 AAAP01003488.1_5 - 0.12 12.8 0.2 0.52 10.8 0.0 2.0 1 1 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain PepSY_2 PF13670.6 AAAP01003488.1_5 - 0.13 12.3 0.5 2.3 8.3 0.4 2.1 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain ABC_tran PF00005.27 AAAP01003489.1_1 - 9.8e-43 146.0 0.0 2e-31 109.3 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAAP01003489.1_1 - 3.9e-07 30.2 0.3 0.00083 19.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 AAAP01003489.1_1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003489.1_1 - 0.00019 21.1 0.2 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01003489.1_1 - 0.0085 15.8 0.1 0.033 13.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AAAP01003489.1_1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AAAP01003489.1_1 - 0.021 15.3 0.0 0.031 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003489.1_1 - 0.029 14.3 0.0 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 AAAP01003489.1_1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF4089 PF13318.6 AAAP01003489.1_4 - 1.2e-17 64.0 1.3 1.6e-17 63.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) Amidase PF01425.21 AAAP01003489.1_5 - 3.3e-05 23.0 0.0 4.1e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Amidase HEAT PF02985.22 AAAP01003489.1_5 - 0.1 12.9 0.3 0.1 12.9 0.3 1.8 2 0 0 2 2 2 0 HEAT repeat CHAT PF12770.7 AAAP01003490.1_1 - 8.8e-79 264.9 0.0 1.6e-78 264.1 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 AAAP01003490.1_1 - 1.6e-30 105.2 12.3 8e-16 58.1 4.4 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003490.1_1 - 1.2e-24 85.4 1.9 1.7e-09 37.3 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003490.1_1 - 1.2e-07 31.2 2.3 0.00033 20.4 0.7 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003490.1_1 - 1.7e-07 30.7 3.8 0.015 15.2 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003490.1_1 - 2.4e-06 27.2 3.6 0.00095 19.1 1.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003490.1_1 - 9.9e-06 25.4 1.7 0.0096 16.1 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003490.1_1 - 7.2e-05 23.2 1.2 0.012 16.1 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003490.1_1 - 8.8e-05 22.0 1.7 0.00011 21.7 1.0 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 AAAP01003490.1_1 - 0.00021 21.9 2.8 0.039 14.6 0.4 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003490.1_1 - 0.004 17.4 1.3 0.42 11.1 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003490.1_1 - 0.032 14.4 0.3 1.9 8.8 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5344 PF17279.2 AAAP01003490.1_1 - 0.053 14.1 0.3 1.4 9.5 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Vac_Fusion PF02346.16 AAAP01003490.1_1 - 0.15 11.7 0.6 24 4.7 0.1 3.0 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Matrilin_ccoil PF10393.9 AAAP01003490.1_1 - 0.63 9.9 1.9 2.4 8.1 1.3 2.4 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TPR_14 PF13428.6 AAAP01003490.1_1 - 0.71 10.8 10.3 3.6 8.7 0.2 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Plug PF07715.15 AAAP01003491.1_1 - 6.3e-21 75.0 2.3 7.3e-21 74.8 0.6 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AAAP01003491.1_1 - 8.2e-06 26.0 9.6 1.1e-05 25.5 9.6 1.2 1 0 0 1 1 1 1 TonB dependent receptor S1 PF00575.23 AAAP01003491.1_2 - 1.3e-18 67.1 0.8 1.9e-18 66.6 0.8 1.3 1 0 0 1 1 1 1 S1 RNA binding domain PHB_acc_N PF07879.11 AAAP01003491.1_2 - 0.011 15.9 0.7 0.091 12.9 0.0 2.2 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain S1_2 PF13509.6 AAAP01003491.1_2 - 0.013 15.6 0.0 0.12 12.4 0.0 2.1 1 1 1 2 2 2 0 S1 domain RNase_PH PF01138.21 AAAP01003491.1_3 - 1.2e-12 48.5 0.0 1.8e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 KH_1 PF00013.29 AAAP01003491.1_3 - 6.2e-07 29.1 0.7 1.5e-06 27.9 0.7 1.7 1 0 0 1 1 1 1 KH domain RNase_PH_C PF03725.15 AAAP01003491.1_3 - 1.5e-06 28.2 0.2 2.4e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Proho_convert PF12177.8 AAAP01003491.1_3 - 0.13 12.3 2.0 0.29 11.1 2.0 1.5 1 0 0 1 1 1 0 Prohormone convertase enzyme Pyr_redox_dim PF02852.22 AAAP01003492.1_1 - 1.8e-37 128.0 0.5 2.1e-37 127.7 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain HATPase_c PF02518.26 AAAP01003492.1_3 - 7.4e-20 71.5 0.0 1.6e-19 70.5 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003492.1_3 - 2.6e-17 63.0 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HPTransfase PF10090.9 AAAP01003492.1_3 - 0.0037 17.1 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain HATPase_c_2 PF13581.6 AAAP01003492.1_3 - 0.0079 16.2 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003492.1_3 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SoxG PF04268.12 AAAP01003492.1_4 - 1.6e-33 116.0 0.4 1.9e-33 115.7 0.4 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family GCV_T PF01571.21 AAAP01003492.1_4 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GlnE PF03710.15 AAAP01003493.1_1 - 9.4e-90 300.4 0.1 2.4e-60 204.0 0.0 2.4 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AAAP01003493.1_1 - 2.9e-42 144.2 1.1 7.2e-42 142.9 1.1 1.7 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase NTP_transf_2 PF01909.23 AAAP01003493.1_1 - 0.011 16.0 0.0 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Nucleotidyltransferase domain DUF294_C PF10335.9 AAAP01003493.1_1 - 0.075 12.8 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Polbeta PF18765.1 AAAP01003493.1_1 - 0.11 12.6 0.0 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase MCPsignal PF00015.21 AAAP01003493.1_2 - 2e-29 102.6 19.7 2e-29 102.6 19.7 2.2 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 AAAP01003493.1_2 - 0.024 14.9 1.3 2.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Casc1_N PF15927.5 AAAP01003493.1_2 - 0.063 13.0 1.4 0.14 11.9 1.4 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus GCN5L1 PF06320.13 AAAP01003493.1_2 - 0.19 11.9 8.5 2 8.6 4.0 2.7 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Gastrin PF00918.17 AAAP01003493.1_2 - 2.5 9.1 10.5 1.4 9.8 4.3 2.8 2 1 1 3 3 3 0 Gastrin/cholecystokinin family DUF812 PF05667.11 AAAP01003493.1_2 - 6.5 5.5 11.0 0.57 9.0 6.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4342 PF14242.6 AAAP01003493.1_3 - 0.2 11.7 1.2 0.24 11.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) ALAD PF00490.21 AAAP01003494.1_1 - 2.2e-141 470.6 0.0 2.6e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AP_endonuc_2 PF01261.24 AAAP01003494.1_1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Lipase_GDSL_2 PF13472.6 AAAP01003494.1_3 - 1e-07 32.5 0.4 1.5e-07 32.0 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family tRNA-synt_2 PF00152.20 AAAP01003495.1_1 - 1.4e-74 251.0 0.0 1.8e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AAAP01003495.1_1 - 7.6e-16 58.1 0.1 1.3e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 GAD domain Sulphotransf PF09037.10 AAAP01003495.1_1 - 0.19 11.2 0.1 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 Stf0 sulphotransferase tRNA-synt_2d PF01409.20 AAAP01003495.1_1 - 0.23 10.9 0.4 6.5 6.2 0.1 2.6 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Glycos_transf_2 PF00535.26 AAAP01003495.1_2 - 4.1e-18 65.8 0.0 5.9e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003495.1_2 - 7.2e-13 48.9 0.2 1.8e-12 47.6 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 AAAP01003495.1_2 - 0.00024 21.5 0.8 0.00051 20.4 0.8 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_transf_7C PF02709.14 AAAP01003495.1_2 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_trans_2_3 PF13632.6 AAAP01003495.1_2 - 0.022 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Autoind_bind PF03472.15 AAAP01003495.1_2 - 0.026 14.0 0.3 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Autoinducer binding domain Glyco_transf_21 PF13506.6 AAAP01003495.1_2 - 0.026 14.0 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Acyl_transf_3 PF01757.22 AAAP01003495.1_3 - 1.8e-13 50.3 1.7 2.2e-13 50.0 1.7 1.0 1 0 0 1 1 1 1 Acyltransferase family OpgC_C PF10129.9 AAAP01003495.1_3 - 0.011 14.6 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 0 OpgC protein DUF87 PF01935.17 AAAP01003496.1_1 - 5.5e-12 46.3 0.0 4.3e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain Tantalus PF15386.6 AAAP01003496.1_1 - 0.059 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Drosophila Tantalus-like MethyltransfD12 PF02086.15 AAAP01003496.1_2 - 8.7e-08 32.1 0.1 1.1e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Biotin_lipoyl_2 PF13533.6 AAAP01003497.1_1 - 9.8e-09 34.9 0.4 9.8e-09 34.9 0.4 1.7 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAAP01003497.1_1 - 3.7e-06 26.3 0.4 5.3e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Cep57_CLD PF14073.6 AAAP01003497.1_1 - 0.0026 17.8 1.1 0.0044 17.1 1.1 1.3 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 HlyD_3 PF13437.6 AAAP01003497.1_1 - 0.0073 17.0 0.2 0.011 16.4 0.2 1.3 1 0 0 1 1 1 1 HlyD family secretion protein DUF4407 PF14362.6 AAAP01003497.1_1 - 0.022 14.1 2.1 0.022 14.1 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Biotin_lipoyl PF00364.22 AAAP01003497.1_1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme YlqD PF11068.8 AAAP01003497.1_1 - 0.41 11.0 3.5 1.1 9.7 3.5 1.7 1 1 0 1 1 1 0 YlqD protein ACR_tran PF00873.19 AAAP01003497.1_2 - 5.1e-89 299.2 0.1 5.8e-89 299.0 0.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ZT_dimer PF16916.5 AAAP01003497.1_2 - 0.02 15.0 1.3 8.7 6.6 0.3 2.7 2 1 0 2 2 2 0 Dimerisation domain of Zinc Transporter HTH_31 PF13560.6 AAAP01003497.1_2 - 1.2 9.6 8.4 1.2 9.6 1.6 3.6 3 1 0 3 3 3 0 Helix-turn-helix domain PrgI PF12666.7 AAAP01003497.1_2 - 2.8 8.7 4.5 6.8 7.5 3.5 2.1 1 1 0 1 1 1 0 PrgI family protein Hemerythrin PF01814.23 AAAP01003498.1_1 - 2e-10 41.4 0.7 2.4e-10 41.2 0.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PAS_3 PF08447.12 AAAP01003498.1_2 - 8.4e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003498.1_2 - 3.5e-09 36.7 0.0 5.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003498.1_2 - 9.5e-09 35.5 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003498.1_2 - 0.012 15.7 0.0 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.10 AAAP01003498.1_2 - 0.023 14.9 0.0 0.052 13.8 0.0 1.7 2 1 0 2 2 2 0 PAS fold MCPsignal PF00015.21 AAAP01003498.1_3 - 7.8e-10 38.8 20.8 7.3e-09 35.7 6.4 3.1 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003498.1_3 - 0.0078 16.6 2.2 0.016 15.6 0.5 2.5 2 0 0 2 2 2 1 HAMP domain BLOC1_2 PF10046.9 AAAP01003498.1_3 - 0.099 13.0 0.3 6.2 7.2 0.0 2.9 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF986 PF06173.12 AAAP01003498.1_3 - 0.13 12.3 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF986) NAGLU_C PF12972.7 AAAP01003498.1_3 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Mn_catalase PF05067.12 AAAP01003499.1_1 - 1e-57 195.3 0.0 1.9e-57 194.4 0.0 1.4 1 1 0 1 1 1 1 Manganese containing catalase DinB_2 PF12867.7 AAAP01003499.1_1 - 0.13 12.8 0.1 4.2 7.9 0.0 2.2 2 0 0 2 2 2 0 DinB superfamily DUF892 PF05974.12 AAAP01003499.1_2 - 5.2e-40 137.1 0.7 5.9e-40 136.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) RhoGEF PF00621.20 AAAP01003499.1_2 - 0.0061 16.8 0.4 0.011 16.0 0.2 1.5 2 0 0 2 2 2 1 RhoGEF domain DUF4164 PF13747.6 AAAP01003499.1_2 - 0.018 15.3 0.8 0.034 14.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Spore_III_AB PF09548.10 AAAP01003499.1_2 - 0.04 14.0 0.8 0.062 13.4 0.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Hint_2 PF13403.6 AAAP01003499.1_3 - 3.1e-48 163.7 0.0 1e-47 162.0 0.0 1.8 2 0 0 2 2 2 1 Hint domain DUF2093 PF09866.9 AAAP01003499.1_3 - 0.0048 16.3 0.1 0.091 12.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2093) GCD14_N PF14801.6 AAAP01003499.1_3 - 0.1 12.4 0.0 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term MCPsignal PF00015.21 AAAP01003499.1_5 - 4.4e-07 29.9 6.8 4.4e-07 29.9 6.8 2.0 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 AAAP01003499.1_5 - 0.0032 17.5 3.9 0.0041 17.2 2.8 1.6 1 1 1 2 2 2 1 Laminin Domain II Seryl_tRNA_N PF02403.22 AAAP01003499.1_5 - 0.0087 16.3 2.9 0.012 15.9 2.9 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Leptin PF02024.15 AAAP01003499.1_5 - 0.026 14.3 0.2 0.036 13.9 0.2 1.2 1 0 0 1 1 1 0 Leptin Sec8_exocyst PF04048.14 AAAP01003499.1_5 - 0.065 13.1 0.4 0.082 12.8 0.4 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain WYL PF13280.6 AAAP01003499.1_5 - 0.079 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 WYL domain DUF948 PF06103.11 AAAP01003499.1_5 - 0.13 12.5 4.8 0.5 10.7 4.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad2 PF08654.10 AAAP01003499.1_5 - 0.16 12.4 3.3 0.33 11.4 3.1 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF3533 PF12051.8 AAAP01003499.1_5 - 0.36 9.7 1.9 0.38 9.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF4148 PF13663.6 AAAP01003500.1_1 - 0.96 9.7 4.5 5 7.4 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4148) DsbC PF11412.8 AAAP01003500.1_2 - 9e-23 80.6 0.0 1.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC DsbD PF02683.15 AAAP01003500.1_2 - 4.2e-14 53.0 11.7 6.4e-14 52.4 11.7 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_7 PF13899.6 AAAP01003500.1_2 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAAP01003500.1_2 - 3.3e-07 30.7 0.0 4.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 AAAP01003500.1_2 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DsbD_2 PF13386.6 AAAP01003500.1_2 - 1.8e-05 24.7 27.1 1.8e-05 24.7 27.1 2.8 1 1 2 3 3 3 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_8 PF13905.6 AAAP01003500.1_2 - 0.069 13.5 0.0 7.8 6.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Response_reg PF00072.24 AAAP01003500.1_3 - 1.9e-20 73.1 0.0 2.7e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003500.1_3 - 3.2e-18 65.6 0.1 5.2e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal 2CSK_N PF08521.10 AAAP01003500.1_4 - 4.6e-18 65.6 0.2 5.9e-18 65.3 0.2 1.1 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal NfeD PF01957.18 AAAP01003500.1_4 - 0.064 13.6 1.3 0.5 10.8 0.1 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PFK PF00365.20 AAAP01003501.1_2 - 9.6e-15 54.7 0.2 1.2e-14 54.4 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase NfeD PF01957.18 AAAP01003501.1_2 - 0.054 13.9 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding PFK PF00365.20 AAAP01003501.1_3 - 1e-29 103.8 0.0 1.3e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase Peptidase_S66 PF02016.15 AAAP01003501.1_3 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain DAGK_cat PF00781.24 AAAP01003501.1_3 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AAAP01003501.1_3 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase DUF465 PF04325.13 AAAP01003501.1_4 - 5.9e-15 55.0 7.2 7.6e-15 54.7 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF465) DivIC PF04977.15 AAAP01003501.1_4 - 0.0043 16.8 2.6 0.85 9.4 0.1 2.0 2 0 0 2 2 2 2 Septum formation initiator Spc7 PF08317.11 AAAP01003501.1_4 - 0.034 13.0 1.2 0.038 12.9 1.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1192 PF06698.11 AAAP01003501.1_4 - 0.045 13.8 3.6 0.2 11.7 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.20 AAAP01003501.1_4 - 0.049 13.6 1.4 0.35 10.8 0.3 1.9 1 1 1 2 2 2 0 Prefoldin subunit FapA PF03961.13 AAAP01003501.1_4 - 0.11 11.0 0.4 0.12 11.0 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 AAAP01003501.1_4 - 0.16 11.9 1.3 0.84 9.6 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 AAAP01003501.1_4 - 0.16 12.1 0.5 0.24 11.6 0.5 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 AAAP01003501.1_4 - 0.21 12.0 5.1 2.5 8.6 0.3 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5595 PF18077.1 AAAP01003501.1_4 - 1.3 9.2 3.8 5.1 7.3 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DASH_Spc19 PF08287.11 AAAP01003501.1_4 - 1.7 8.5 7.4 14 5.5 7.4 1.9 1 1 0 1 1 1 0 Spc19 HPPK PF01288.20 AAAP01003501.1_5 - 3.7e-34 117.6 0.0 4.5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Beta-lactamase PF00144.24 AAAP01003502.1_2 - 1.2e-35 123.3 2.9 2e-35 122.6 2.9 1.4 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 AAAP01003502.1_2 - 1.2e-26 93.2 0.0 1e-13 51.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3471) Aldedh PF00171.22 AAAP01003502.1_3 - 2.6e-91 306.5 0.0 3.2e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 AAAP01003502.1_3 - 0.0096 15.9 1.2 0.026 14.5 0.8 1.9 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated ketoacyl-synt PF00109.26 AAAP01003503.1_1 - 9.8e-23 81.0 1.6 1.5e-22 80.4 1.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FabA PF07977.13 AAAP01003503.1_2 - 3.2e-48 162.9 0.0 3.8e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain FUR PF01475.19 AAAP01003503.1_3 - 3.9e-20 72.2 0.0 4.4e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_Tnp_Tc3_2 PF01498.18 AAAP01003503.1_3 - 0.015 15.5 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_20 PF12840.7 AAAP01003503.1_3 - 0.032 14.3 0.7 0.68 10.0 0.1 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain TPR_12 PF13424.6 AAAP01003503.1_3 - 0.17 12.2 0.4 6.5 7.1 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat SH3_4 PF06347.13 AAAP01003503.1_4 - 9.3e-30 102.2 1.8 6.2e-19 67.6 0.1 2.4 2 1 0 2 2 2 2 Bacterial SH3 domain SH3_3 PF08239.11 AAAP01003503.1_4 - 2.8e-07 30.7 0.1 1.6e-05 25.1 0.1 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain ACC_epsilon PF13822.6 AAAP01003503.1_4 - 0.22 12.2 4.9 0.22 12.2 0.4 2.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit 2-Hacid_dh PF00389.30 AAAP01003503.1_5 - 6e-25 87.4 0.2 6.8e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain OrgA_MxiK PF09482.10 AAAP01003503.1_5 - 0.18 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) AAA_16 PF13191.6 AAAP01003504.1_1 - 2.9e-44 151.4 1.0 1.4e-43 149.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 AAAP01003504.1_1 - 0.0017 17.6 0.0 0.28 10.3 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain RsgA_GTPase PF03193.16 AAAP01003504.1_1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 AAAP01003504.1_1 - 0.0032 16.7 0.0 0.058 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 AAAP01003504.1_1 - 0.0084 15.8 0.7 0.032 14.0 0.0 2.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 AAAP01003504.1_1 - 0.0097 16.2 0.0 0.072 13.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 AAAP01003504.1_1 - 0.019 14.9 0.0 0.081 12.8 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 AAAP01003504.1_1 - 0.024 13.9 0.0 0.061 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 AAAP01003504.1_1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TonB_dep_Rec PF00593.24 AAAP01003505.1_1 - 6.1e-13 49.5 2.3 7.8e-13 49.1 2.3 1.0 1 0 0 1 1 1 1 TonB dependent receptor Aminotran_1_2 PF00155.21 AAAP01003505.1_3 - 5e-45 154.2 0.0 6.2e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAAP01003505.1_3 - 7.4e-06 25.5 0.1 1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAAP01003505.1_3 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01003505.1_3 - 0.06 11.9 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CCG PF02754.16 AAAP01003506.1_1 - 7.9e-16 58.0 0.2 1e-13 51.3 0.1 2.2 2 0 0 2 2 2 2 Cysteine-rich domain Response_reg PF00072.24 AAAP01003506.1_2 - 1.1e-12 48.1 0.0 1.9e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Response regulator receiver domain OKR_DC_1_N PF03709.15 AAAP01003506.1_2 - 0.0093 16.2 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain ThiG PF05690.14 AAAP01003506.1_2 - 0.029 13.7 0.3 0.038 13.3 0.3 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG ADH_zinc_N PF00107.26 AAAP01003506.1_3 - 1.7e-26 92.7 0.1 2.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01003506.1_3 - 2.9e-15 57.5 0.0 5.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003506.1_3 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AAAP01003506.1_3 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 AAAP01003506.1_3 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SIC PF03482.13 AAAP01003506.1_4 - 0.49 10.6 3.1 0.73 10.1 0.6 2.1 2 0 0 2 2 2 0 sic protein repeat Arginase PF00491.21 AAAP01003507.1_1 - 8.5e-85 284.6 0.0 1.1e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family HD PF01966.22 AAAP01003507.1_2 - 1.7e-21 76.7 0.2 3e-21 75.9 0.2 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01003507.1_2 - 4.1e-15 55.8 0.0 8.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAAP01003507.1_2 - 5.5e-05 22.7 0.2 0.0002 20.9 0.2 1.8 1 1 0 1 1 1 1 HDOD domain HD_6 PF18019.1 AAAP01003507.1_2 - 0.042 14.0 0.2 0.075 13.1 0.2 1.3 1 0 0 1 1 1 0 HD domain HD_3 PF13023.6 AAAP01003507.1_2 - 0.064 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 HD domain HD_2 PF12917.7 AAAP01003507.1_2 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme YccV-like PF08755.11 AAAP01003507.1_4 - 4.9e-25 87.9 0.0 6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like HpcH_HpaI PF03328.14 AAAP01003507.1_5 - 6.8e-18 64.6 0.0 2.5e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01003507.1_5 - 0.031 13.4 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold Isochorismatase PF00857.20 AAAP01003508.1_2 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family HTH_3 PF01381.22 AAAP01003508.1_3 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003508.1_3 - 0.0002 21.7 1.4 0.00024 21.4 0.9 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003508.1_3 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_psq PF05225.16 AAAP01003508.1_3 - 0.0014 18.4 0.0 0.0041 16.8 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_29 PF13551.6 AAAP01003508.1_3 - 0.0027 17.7 0.1 0.005 16.8 0.1 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_8 PF02954.19 AAAP01003508.1_3 - 0.013 15.2 0.6 0.026 14.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 AAAP01003508.1_3 - 0.05 13.7 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 AAAP01003508.1_3 - 0.15 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 AAAP01003508.1_3 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ATPase PF06745.13 AAAP01003508.1_4 - 2.3e-29 102.4 0.0 2.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 AAAP01003508.1_4 - 2.2e-06 27.4 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003508.1_4 - 1.2e-05 25.8 0.1 1.8e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 AAAP01003508.1_4 - 0.00017 21.0 0.0 0.00051 19.5 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA PF00004.29 AAAP01003508.1_4 - 0.0016 18.9 0.0 0.0036 17.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AAAP01003508.1_4 - 0.0023 17.7 0.0 0.0064 16.2 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein GvpD PF07088.11 AAAP01003508.1_4 - 0.0034 16.1 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 GvpD gas vesicle protein RecA PF00154.21 AAAP01003508.1_4 - 0.0072 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_14 PF13173.6 AAAP01003508.1_4 - 0.0076 16.3 0.0 0.029 14.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.9 AAAP01003508.1_4 - 0.0091 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 AAAP01003508.1_4 - 0.019 15.2 0.2 0.057 13.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 AAAP01003508.1_4 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) MEDS PF14417.6 AAAP01003508.1_4 - 0.028 14.2 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_5 PF07728.14 AAAP01003508.1_4 - 0.032 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AAAP01003508.1_4 - 0.036 13.8 0.1 0.049 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003508.1_4 - 0.038 13.7 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 AAAP01003508.1_4 - 0.039 13.2 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Rad51 AAA_29 PF13555.6 AAAP01003508.1_4 - 0.045 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 AAAP01003508.1_4 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01003508.1_4 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Adenine_glyco PF03352.13 AAAP01003509.1_2 - 1.8e-73 246.1 0.0 3.4e-73 245.2 0.0 1.4 2 0 0 2 2 2 1 Methyladenine glycosylase HD_2 PF12917.7 AAAP01003509.1_3 - 8.9e-06 25.6 0.0 0.00099 18.9 0.0 2.8 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD_3 PF13023.6 AAAP01003509.1_3 - 0.00078 19.4 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003509.1_3 - 0.0049 17.1 0.0 0.0095 16.2 0.0 1.5 1 1 0 1 1 1 1 HD domain PTPlike_phytase PF14566.6 AAAP01003509.1_4 - 0.016 15.4 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 AAAP01003509.1_4 - 0.045 13.3 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 AAAP01003509.1_4 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Exonuc_VII_S PF02609.16 AAAP01003509.1_5 - 4.7e-21 74.6 0.7 5.7e-21 74.3 0.7 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit DXP_synthase_N PF13292.6 AAAP01003509.1_6 - 1e-46 159.4 0.0 1.1e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 AAAP01003509.1_6 - 0.21 10.5 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain EutC PF05985.11 AAAP01003510.1_1 - 2.3e-05 23.8 0.0 2.6e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) EutB PF06751.11 AAAP01003510.1_2 - 9.6e-217 720.0 0.0 1.2e-216 719.7 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) MFS_1 PF07690.16 AAAP01003510.1_3 - 1.2e-21 77.1 18.6 1.4e-21 76.8 18.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01003510.1_3 - 0.0018 17.2 3.4 0.0021 17.0 3.4 1.2 1 0 0 1 1 1 1 MFS_1 like family Phage_TAC_11 PF11836.8 AAAP01003511.1_1 - 4.8e-18 65.1 3.6 6.9e-18 64.6 3.6 1.2 1 0 0 1 1 1 1 Phage tail tube protein, GTA-gp10 Phage_tail_2 PF06199.11 AAAP01003511.1_2 - 3.3e-26 92.0 0.1 3.9e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Phage tail tube protein MLVIN_C PF18697.1 AAAP01003511.1_2 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain HK97-gp10_like PF04883.12 AAAP01003511.1_4 - 1.2e-11 45.4 1.6 1.4e-11 45.2 0.1 1.8 2 0 0 2 2 2 1 Bacteriophage HK97-gp10, putative tail-component Phage_H_T_join PF05521.11 AAAP01003511.1_5 - 2.8e-15 56.6 0.1 3.2e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Phage head-tail joining protein Phage_connect_1 PF05135.13 AAAP01003511.1_6 - 0.00011 22.6 0.0 0.00015 22.2 0.0 1.2 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein MCPsignal PF00015.21 AAAP01003512.1_1 - 1.5e-28 99.7 20.3 1.8e-28 99.5 19.8 1.3 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HATPase_c PF02518.26 AAAP01003512.1_2 - 6.2e-22 78.2 0.1 9.7e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003512.1_2 - 1.8e-18 66.7 0.0 4.2e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003512.1_2 - 2.1e-09 37.3 0.6 3.1e-08 33.5 0.0 2.5 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003512.1_2 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 GHKL domain KR PF08659.10 AAAP01003512.1_2 - 0.095 12.6 0.1 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 KR domain Response_reg PF00072.24 AAAP01003512.1_3 - 1.8e-16 60.3 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAAP01003512.1_3 - 0.0093 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 AAAP01003512.1_3 - 0.037 13.6 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Phage_holin_2_3 PF16080.5 AAAP01003512.1_3 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 PAS_8 PF13188.7 AAAP01003512.1_3 - 0.16 12.0 0.0 0.68 10.0 0.0 2.2 1 0 0 1 1 1 0 PAS domain DUF1275 PF06912.11 AAAP01003513.1_1 - 5.3e-29 101.5 24.4 6.4e-29 101.3 24.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.6 AAAP01003513.1_1 - 3.5 7.2 11.2 1.7 8.3 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_11 PF08241.12 AAAP01003513.1_2 - 9e-18 64.7 0.1 1.9e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003513.1_2 - 1.2e-16 61.1 0.1 3.5e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003513.1_2 - 7.1e-14 52.4 0.0 1.3e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003513.1_2 - 9.2e-12 45.1 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003513.1_2 - 1.3e-10 41.3 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPR_14 PF13428.6 AAAP01003513.1_2 - 6.2e-07 29.7 4.1 6.2e-07 29.7 4.1 4.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003513.1_2 - 1.1e-05 25.3 2.8 0.65 10.4 0.6 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Ubie_methyltran PF01209.18 AAAP01003513.1_2 - 6.8e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AAAP01003513.1_2 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 AAAP01003513.1_2 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AAAP01003513.1_2 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_2 PF07719.17 AAAP01003513.1_2 - 0.0028 17.6 14.7 0.092 12.9 2.9 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003513.1_2 - 0.0049 17.4 15.0 0.0086 16.6 3.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003513.1_2 - 0.0053 17.0 0.2 0.091 13.2 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003513.1_2 - 0.0055 16.5 4.9 0.71 9.8 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003513.1_2 - 0.012 15.3 0.7 1.6 8.5 0.2 2.7 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 AAAP01003513.1_2 - 0.02 15.5 2.5 0.02 15.5 2.5 5.9 6 1 1 7 7 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003513.1_2 - 0.022 15.4 12.4 0.022 15.4 12.4 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat MetW PF07021.12 AAAP01003513.1_2 - 0.027 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 AAAP01003513.1_2 - 0.051 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 AAAP01003513.1_2 - 0.11 12.2 0.0 14 5.3 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_32 PF13679.6 AAAP01003513.1_2 - 0.23 11.5 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPR_12 PF13424.6 AAAP01003513.1_2 - 0.91 9.9 14.2 0.09 13.1 1.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003513.1_2 - 2.9 8.1 10.1 9.7 6.5 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 AAAP01003513.1_3 - 1.6e-06 27.8 0.6 7.8e-06 25.5 0.2 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01003513.1_3 - 8.2e-06 26.0 1.3 0.04 13.9 0.3 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily NicO PF03824.16 AAAP01003514.1_1 - 2e-05 24.1 12.0 2.2e-05 24.0 12.0 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein EutK_C PF16365.5 AAAP01003514.1_1 - 0.2 11.7 2.7 0.41 10.7 2.7 1.7 1 1 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus His_Phos_1 PF00300.22 AAAP01003514.1_3 - 5e-20 72.0 1.0 7.6e-20 71.4 1.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phage_tail_APC PF16778.5 AAAP01003514.1_3 - 0.043 13.7 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Multi_Drug_Res PF00893.19 AAAP01003514.1_4 - 6.5e-29 100.4 9.5 8.7e-29 100.0 9.5 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AAAP01003514.1_4 - 0.0031 17.7 14.7 0.0036 17.5 14.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family BiPBP_C PF06832.12 AAAP01003514.1_5 - 1e-22 79.9 0.1 1.1e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family BcsB PF03170.13 AAAP01003515.1_1 - 8.3e-34 116.9 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial cellulose synthase subunit CBM-like PF14683.6 AAAP01003515.1_1 - 0.012 15.5 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III Tr-sialidase_C PF11052.8 AAAP01003515.1_1 - 7.5 6.8 9.6 2.9 8.1 2.2 2.7 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal Glycos_transf_2 PF00535.26 AAAP01003515.1_3 - 4e-33 114.6 0.0 6e-33 114.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAAP01003515.1_3 - 8.9e-17 61.1 0.0 1.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 AAAP01003515.1_3 - 1e-16 61.5 0.0 1.2e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003515.1_3 - 5.5e-16 59.1 0.0 7.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 AAAP01003515.1_3 - 3.4e-07 29.2 0.0 0.0077 14.8 0.0 2.8 2 1 1 3 3 3 2 Cellulose synthase SBP_bac_3 PF00497.20 AAAP01003516.1_1 - 3e-40 138.0 0.0 3.8e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAAP01003516.1_1 - 9.6e-06 25.8 0.0 0.00028 21.1 0.0 2.5 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site PAS_9 PF13426.7 AAAP01003516.1_2 - 6.5e-18 64.9 0.0 1.4e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AAAP01003516.1_2 - 5.7e-11 42.6 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold dCache_1 PF02743.18 AAAP01003516.1_2 - 3.6e-10 40.1 0.0 7.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Cache domain PAS_4 PF08448.10 AAAP01003516.1_2 - 6.8e-10 39.2 0.2 1.9e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAAP01003516.1_2 - 8.6e-09 35.4 0.0 2.1e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003516.1_2 - 0.002 18.1 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain Nitrate_red_gam PF02665.14 AAAP01003516.1_2 - 0.028 14.0 1.1 0.056 13.0 1.1 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit HisKA PF00512.25 AAAP01003516.1_2 - 1.1 9.3 4.0 1.4 9.0 1.4 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Totivirus_coat PF05518.11 AAAP01003517.1_1 - 9.1 4.2 8.5 9.5 4.1 8.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein PDEase_I_N PF08499.12 AAAP01003517.1_3 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Biotin_lipoyl PF00364.22 AAAP01003518.1_1 - 9.9e-20 70.2 1.7 1.4e-19 69.7 1.7 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAAP01003518.1_1 - 6.1e-05 22.8 0.6 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like E1_dh PF00676.20 AAAP01003518.1_2 - 1.8e-99 332.5 0.1 2.1e-99 332.3 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AAAP01003518.1_2 - 0.00016 21.5 1.5 0.00054 19.8 1.5 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 AAAP01003518.1_2 - 0.00029 20.1 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF4630 PF15443.6 AAAP01003518.1_2 - 0.16 12.1 0.3 0.37 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) OEP PF02321.18 AAAP01003518.1_3 - 1.6e-23 83.5 2.5 1.9e-23 83.3 2.5 1.1 1 0 0 1 1 1 1 Outer membrane efflux protein TBCA PF02970.16 AAAP01003518.1_3 - 0.049 13.9 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Tubulin binding cofactor A ATP12 PF07542.11 AAAP01003519.1_1 - 2e-05 24.7 0.0 2.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 ATP12 chaperone protein HAD_2 PF13419.6 AAAP01003519.1_2 - 1.6e-35 122.8 0.0 1.9e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003519.1_2 - 5.1e-20 72.7 0.0 8.8e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003519.1_2 - 4.8e-12 46.7 0.1 6.4e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003519.1_2 - 6.2e-11 42.2 0.2 1.6e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 AAAP01003519.1_2 - 4.2e-06 26.7 0.1 0.29 10.8 0.0 3.1 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AAAP01003519.1_2 - 0.066 12.6 0.0 4.2 6.7 0.0 2.2 2 1 0 2 2 2 0 Putative Phosphatase Hydrolase_6 PF13344.6 AAAP01003519.1_2 - 0.072 13.2 0.0 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GGDEF_2 PF17853.1 AAAP01003519.1_2 - 0.15 12.4 0.5 5 7.4 0.1 2.9 2 2 1 3 3 3 0 GGDEF-like domain NIF PF03031.18 AAAP01003519.1_2 - 0.18 11.6 0.0 1.1 9.1 0.0 1.9 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase RhodobacterPufX PF11511.8 AAAP01003519.1_2 - 0.26 10.9 1.8 3.1 7.5 1.2 2.4 2 0 0 2 2 2 0 Intrinsic membrane protein PufX PsiF_repeat PF07769.14 AAAP01003519.1_3 - 0.041 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 psiF repeat DEC-1_N PF04625.13 AAAP01003519.1_3 - 0.19 10.7 10.0 0.23 10.4 10.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PseudoU_synth_2 PF00849.22 AAAP01003519.1_4 - 1.4e-30 106.5 0.0 2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAAP01003519.1_4 - 2.3e-05 24.0 0.0 5.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain Plug PF07715.15 AAAP01003520.1_1 - 2.8e-15 56.8 0.1 5.2e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Radical_SAM PF04055.21 AAAP01003520.1_2 - 9.3e-17 61.9 0.1 7e-16 59.0 0.1 2.1 1 1 0 1 1 1 1 Radical SAM superfamily SIP PF04954.13 AAAP01003521.1_1 - 1.9e-35 121.9 1.5 3.6e-35 121.1 1.5 1.5 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 AAAP01003521.1_1 - 4.5e-32 110.8 0.0 7.5e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain TonB_dep_Rec PF00593.24 AAAP01003521.1_2 - 6.3e-30 105.5 12.9 7.6e-30 105.2 12.9 1.0 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AAAP01003521.1_2 - 5.3e-09 35.6 1.4 6.9e-09 35.2 1.4 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family OMP_b-brl PF13505.6 AAAP01003521.1_2 - 0.00097 19.3 6.1 0.0014 18.8 6.1 1.4 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Autotransporter PF03797.19 AAAP01003521.1_2 - 0.006 16.3 5.5 1.6 8.3 0.3 3.1 2 1 1 3 3 3 2 Autotransporter beta-domain MtrB_PioB PF11854.8 AAAP01003521.1_2 - 0.049 12.0 1.6 0.072 11.4 0.1 1.8 2 0 0 2 2 2 0 Putative outer membrane beta-barrel porin, MtrB/PioB Antig_Caf1 PF09255.10 AAAP01003521.1_2 - 0.068 13.3 0.2 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 Caf1 Capsule antigen zf-ISL3 PF14690.6 AAAP01003521.1_3 - 1.2e-08 35.4 3.7 1.6e-08 35.1 2.7 1.7 1 1 1 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PyrI PF01948.18 AAAP01003521.1_3 - 0.14 12.4 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain FTP PF07504.13 AAAP01003521.1_3 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DctP PF03480.13 AAAP01003522.1_1 - 9e-40 136.8 0.0 1.1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 PSDC PF12588.8 AAAP01003522.1_1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase DctM PF06808.12 AAAP01003522.1_2 - 3e-122 408.5 44.8 3.4e-122 408.2 44.8 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component ABC_tran PF00005.27 AAAP01003523.1_1 - 5.1e-16 59.4 0.0 8.3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003523.1_1 - 5.9e-05 23.0 0.3 0.085 12.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01003523.1_1 - 0.00022 21.5 0.3 0.001 19.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003523.1_1 - 0.0013 19.1 0.9 0.0013 19.1 0.9 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003523.1_1 - 0.0031 17.2 0.3 0.0074 16.0 0.3 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003523.1_1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 AAAP01003523.1_1 - 0.017 15.4 0.2 0.046 14.0 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003523.1_1 - 0.026 14.9 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAAP01003523.1_1 - 0.029 14.3 0.1 0.064 13.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 AAAP01003523.1_1 - 0.062 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 AAAP01003523.1_1 - 0.069 13.2 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01003523.1_1 - 0.075 12.6 4.1 1.4 8.4 0.2 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 AAAP01003523.1_1 - 0.097 12.1 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AAAP01003523.1_1 - 0.11 12.6 0.3 0.28 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Septin PF00735.18 AAAP01003523.1_1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 AAAP01003523.1_1 - 0.22 11.3 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 AAAP01003523.1_1 - 0.35 10.0 0.1 0.59 9.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 AAAP01003523.1_2 - 3.6e-16 59.9 0.0 1.7e-15 57.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003523.1_2 - 1.3e-07 31.8 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003523.1_2 - 0.001 19.5 1.9 0.0052 17.2 1.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAAP01003523.1_2 - 0.0012 18.3 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003523.1_2 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003523.1_2 - 0.0031 18.1 0.0 0.0043 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003523.1_2 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AAAP01003523.1_2 - 0.0065 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01003523.1_2 - 0.014 15.7 0.3 0.039 14.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01003523.1_2 - 0.017 14.7 0.1 0.044 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003523.1_2 - 0.032 14.4 0.1 0.053 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003523.1_2 - 0.033 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003523.1_2 - 0.053 14.1 0.3 0.091 13.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003523.1_2 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 AAAP01003523.1_2 - 0.073 12.8 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Cytidylate kinase Rad17 PF03215.15 AAAP01003523.1_2 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain DBI_PRT PF02277.17 AAAP01003524.1_1 - 1.5e-05 24.4 0.0 1.7e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase CobS PF02654.15 AAAP01003524.1_2 - 7.3e-50 170.0 18.3 8.5e-50 169.8 18.3 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DUF1289 PF06945.13 AAAP01003524.1_3 - 4.1e-19 68.1 0.2 5e-19 67.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) gag-asp_proteas PF13975.6 AAAP01003524.1_4 - 5.5e-21 74.9 0.1 7.1e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AAAP01003524.1_4 - 5.5e-20 71.8 0.1 7.2e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 Aspartyl protease PCMT PF01135.19 AAAP01003525.1_1 - 5.6e-19 68.7 0.4 6.8e-19 68.4 0.4 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AAAP01003525.1_1 - 0.0035 16.4 0.0 0.0035 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cytadhesin_P30 PF07271.11 AAAP01003525.1_1 - 0.046 13.3 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 ICAP-1_inte_bdg PF10480.9 AAAP01003525.1_1 - 0.11 12.4 0.4 0.18 11.8 0.2 1.4 2 0 0 2 2 2 0 Beta-1 integrin binding protein OEP PF02321.18 AAAP01003525.1_2 - 1.4e-57 194.6 22.8 9e-30 103.9 8.6 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DUF2497 PF10691.9 AAAP01003525.1_3 - 4.5e-20 71.9 0.1 8.4e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2497) Trypan_PARP PF05887.11 AAAP01003525.1_3 - 0.75 9.8 77.1 0.49 10.4 32.1 2.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) EamA PF00892.20 AAAP01003526.1_1 - 6.5e-21 74.9 30.8 6.9e-11 42.5 6.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2178 PF09946.9 AAAP01003526.1_1 - 0.024 14.8 0.3 0.024 14.8 0.3 2.7 3 1 0 3 3 3 0 Predicted membrane protein (DUF2178) adh_short PF00106.25 AAAP01003526.1_2 - 1.1e-52 178.3 0.0 1.4e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003526.1_2 - 1.6e-36 126.0 0.1 2e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003526.1_2 - 1.7e-11 44.4 0.0 2.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003526.1_2 - 4.1e-06 26.4 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AAAP01003526.1_2 - 0.00057 19.1 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 AAAP01003526.1_2 - 0.00092 19.7 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAAP01003526.1_2 - 0.0022 18.2 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AAAP01003526.1_2 - 0.024 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 AAAP01003526.1_2 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_23 PF13489.6 AAAP01003527.1_1 - 0.00036 20.4 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003527.1_1 - 0.0073 17.0 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003527.1_1 - 0.096 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-HC2 PF13490.6 AAAP01003527.1_2 - 1.1e-05 25.6 0.4 3.2e-05 24.1 0.4 1.8 1 0 0 1 1 1 1 Putative zinc-finger VbhA PF18495.1 AAAP01003527.1_2 - 0.00034 20.4 0.7 0.0025 17.6 0.0 2.8 2 0 0 2 2 2 1 Antitoxin VbhA Sigma70_r2 PF04542.14 AAAP01003527.1_3 - 3.2e-15 55.7 1.1 6.8e-15 54.6 0.4 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAAP01003527.1_3 - 3.3e-13 49.1 0.1 6e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003527.1_3 - 1.4e-06 27.7 1.1 2.5e-06 26.9 0.0 2.1 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAAP01003527.1_3 - 8.8e-06 25.7 2.1 1.1e-05 25.4 2.1 1.1 1 0 0 1 1 1 1 ECF sigma factor YkuD PF03734.14 AAAP01003527.1_4 - 2e-23 83.4 0.1 2.9e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Exonuc_VII_L PF02601.15 AAAP01003528.1_1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit MDMPI_C PF07398.11 AAAP01003528.1_1 - 0.49 11.3 9.8 0.094 13.6 3.9 2.6 1 1 1 2 2 2 0 MDMPI C-terminal domain MFS_1 PF07690.16 AAAP01003529.1_1 - 5.7e-11 41.9 9.2 6.6e-11 41.7 9.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAAP01003529.1_1 - 0.0006 18.5 3.1 0.00072 18.2 3.1 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Phage_integrase PF00589.22 AAAP01003529.1_4 - 1.8e-07 31.1 0.1 3.7e-06 26.8 0.0 2.9 2 2 0 2 2 2 1 Phage integrase family SecY PF00344.20 AAAP01003530.1_1 - 2.3e-10 40.2 2.2 2.6e-10 40.0 2.2 1.0 1 0 0 1 1 1 1 SecY translocase ADK PF00406.22 AAAP01003530.1_2 - 2.4e-57 193.3 0.0 2.9e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AAAP01003530.1_2 - 1.7e-22 80.3 0.2 3.2e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 AAAP01003530.1_2 - 7e-13 48.3 0.9 1.2e-12 47.6 0.9 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 AAAP01003530.1_2 - 7.8e-05 22.9 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 AAAP01003530.1_2 - 0.00015 22.2 0.2 0.29 11.4 0.0 2.2 1 1 0 2 2 2 2 Hydin Adenylate kinase-like domain DUF1451 PF07295.11 AAAP01003530.1_2 - 0.00034 20.7 0.6 0.00074 19.6 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon containing domain AAA_18 PF13238.6 AAAP01003530.1_2 - 0.00091 19.8 0.0 0.0015 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AAAP01003530.1_2 - 0.006 16.3 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase HypA PF01155.19 AAAP01003530.1_2 - 0.03 14.4 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mg_chelatase PF01078.21 AAAP01003530.1_2 - 0.055 12.9 0.1 0.088 12.2 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-IS66 PF13005.7 AAAP01003530.1_2 - 0.072 13.5 0.9 2.2 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Rubredoxin_2 PF18073.1 AAAP01003530.1_2 - 0.08 12.7 4.1 1 9.2 4.1 2.1 1 1 0 1 1 1 0 Rubredoxin metal binding domain AAA PF00004.29 AAAP01003530.1_2 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 AAAP01003530.1_2 - 0.23 11.6 1.9 0.42 10.8 1.9 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Ribosomal_S13 PF00416.22 AAAP01003530.1_3 - 7.4e-32 110.4 6.3 2.6e-30 105.4 6.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_S11 PF00411.19 AAAP01003530.1_4 - 5e-06 26.9 0.8 7.1e-06 26.4 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S11 PF00411.19 AAAP01003530.1_5 - 8.1e-34 116.3 0.7 8.7e-34 116.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 RNA_pol_A_bac PF01000.26 AAAP01003530.1_6 - 3.3e-17 62.9 0.0 4.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 AAAP01003530.1_6 - 2e-11 43.2 0.0 2.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prim-Pol PF09250.11 AAAP01003531.1_1 - 2.7e-06 27.8 0.1 6.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal AAA_16 PF13191.6 AAAP01003531.1_1 - 8.8e-05 23.0 0.1 0.00031 21.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF3892 PF13031.6 AAAP01003531.1_2 - 0.0017 19.0 1.2 0.0019 18.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3892) DUF2235 PF09994.9 AAAP01003531.1_3 - 2.5e-21 76.3 0.0 3.4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HTH_31 PF13560.6 AAAP01003532.1_2 - 1.1e-08 35.3 9.3 2e-08 34.4 5.2 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003532.1_2 - 4.1e-08 33.2 1.0 6.7e-08 32.5 1.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003532.1_2 - 1.9e-06 27.8 0.1 3.1e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01003532.1_2 - 2.3e-06 27.5 0.1 3.7e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAAP01003532.1_2 - 0.00056 19.7 0.4 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 AAAP01003532.1_2 - 0.0024 17.7 1.6 0.0052 16.7 0.3 2.0 2 0 0 2 2 2 1 MarR family HTH_26 PF13443.6 AAAP01003532.1_2 - 0.027 14.9 0.1 0.038 14.4 0.1 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF2316 PF10078.9 AAAP01003532.1_2 - 0.033 14.4 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_20 PF12840.7 AAAP01003532.1_2 - 0.033 14.2 0.2 0.072 13.2 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01003532.1_2 - 0.054 13.3 0.9 0.17 11.7 0.9 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain POTRA_TamA_1 PF17243.2 AAAP01003532.1_2 - 0.12 12.5 1.7 15 5.8 0.8 2.4 1 1 2 3 3 3 0 POTRA domain TamA domain 1 Cro PF09048.10 AAAP01003532.1_2 - 0.52 10.4 1.9 1.4 9.0 0.1 2.1 1 1 1 2 2 2 0 Cro HHH PF00633.23 AAAP01003532.1_3 - 0.009 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AAAP01003532.1_3 - 0.1 13.2 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain PfkB PF00294.24 AAAP01003532.1_5 - 1.1e-08 34.8 1.6 1.5e-08 34.3 1.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase IstB_IS21 PF01695.17 AAAP01003533.1_1 - 1.8e-07 31.1 0.1 2e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein YqcI_YcgG PF08892.11 AAAP01003533.1_2 - 3.2e-54 184.0 0.0 3.6e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 YqcI/YcgG family TetR_C_31 PF17940.1 AAAP01003533.1_2 - 0.26 11.5 3.5 0.51 10.6 1.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HATPase_c PF02518.26 AAAP01003534.1_1 - 1e-17 64.7 0.0 2.9e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003534.1_1 - 6.4e-11 42.4 0.2 6.4e-11 42.4 0.2 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003534.1_1 - 2.6e-09 37.0 0.3 6.8e-09 35.6 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003534.1_1 - 0.00089 19.5 0.0 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain HPTransfase PF10090.9 AAAP01003534.1_1 - 0.0019 18.0 0.2 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain PAS_4 PF08448.10 AAAP01003534.1_1 - 0.015 15.5 0.3 0.12 12.6 0.0 2.4 1 1 1 2 2 2 0 PAS fold HATPase_c_3 PF13589.6 AAAP01003534.1_1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAAP01003534.1_2 - 2.2e-32 111.2 0.0 3.4e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01003534.1_2 - 3.2e-21 75.4 0.0 1.5e-13 50.8 0.0 3.1 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AAAP01003534.1_2 - 4.8e-10 39.2 2.3 6.5e-06 26.0 0.0 3.5 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AAAP01003534.1_2 - 1.6e-09 38.0 6.3 3.1e-08 33.9 0.3 3.6 3 1 0 3 3 3 1 PAS fold PAS_9 PF13426.7 AAAP01003534.1_2 - 8.5e-09 35.6 0.0 1.4e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 PAS domain LcrG PF07216.12 AAAP01003534.1_2 - 0.63 10.0 3.7 2.9 7.9 0.3 2.7 3 0 0 3 3 3 0 LcrG protein Putative_PNPOx PF01243.20 AAAP01003534.1_3 - 1.5e-13 50.7 0.1 3.1e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 AAAP01003534.1_3 - 1.7e-12 47.8 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AAAP01003534.1_3 - 1.4e-05 24.7 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like MutL_C PF08676.11 AAAP01003534.1_4 - 5.8e-36 123.5 0.0 8.5e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 MutL C terminal dimerisation domain Phage_integrase PF00589.22 AAAP01003535.1_1 - 3e-14 53.2 0.0 3.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF5490 PF17593.2 AAAP01003535.1_3 - 0.097 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5490) ECH_1 PF00378.20 AAAP01003536.1_1 - 6.5e-36 123.9 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003536.1_1 - 8.2e-21 74.8 0.0 1.1e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ADH_N PF08240.12 AAAP01003536.1_2 - 8.7e-28 96.4 3.2 1.9e-27 95.3 3.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AAAP01003536.1_2 - 1.9e-19 69.9 0.0 3.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01003536.1_2 - 1e-06 28.2 0.6 1.5e-06 27.7 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 AAAP01003536.1_2 - 0.0031 17.6 3.3 0.02 15.0 1.1 2.5 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AAAP01003536.1_2 - 0.0093 15.6 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 AAAP01003536.1_2 - 0.012 15.8 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 AAAP01003536.1_2 - 0.016 14.8 0.8 0.025 14.1 0.8 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 AAAP01003536.1_2 - 0.032 14.9 0.2 0.12 13.0 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 AAAP01003536.1_2 - 0.038 13.4 0.3 0.071 12.5 0.3 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MoCF_biosynth PF00994.24 AAAP01003536.1_2 - 0.04 13.6 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain TPP_enzyme_M PF00205.22 AAAP01003536.1_2 - 0.055 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DegT_DnrJ_EryC1 PF01041.17 AAAP01003536.1_2 - 0.058 12.7 0.7 0.082 12.2 0.7 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 3HCDH_N PF02737.18 AAAP01003536.1_2 - 0.097 12.5 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 AAAP01003536.1_2 - 0.1 13.3 0.2 0.51 11.0 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain POR PF01558.18 AAAP01003536.1_3 - 1.5e-06 28.4 0.1 1.5e-06 28.4 0.1 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase GTP_EFTU_D3 PF03143.17 AAAP01003537.1_1 - 1.5e-33 115.5 0.0 2.9e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAAP01003537.1_1 - 1.9e-17 63.4 6.6 1e-16 61.1 6.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Lsm_C PF14894.6 AAAP01003537.1_1 - 0.086 12.6 4.0 0.18 11.6 4.0 1.5 1 0 0 1 1 1 0 Lsm C-terminal SecE PF00584.20 AAAP01003537.1_2 - 5.2e-20 71.1 6.9 5.7e-20 71.0 6.9 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NusG PF02357.19 AAAP01003537.1_3 - 4.3e-28 97.7 0.2 5.8e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 AAAP01003537.1_3 - 1.3e-06 28.2 0.2 4.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 KOW motif PolyG_pol PF01518.16 AAAP01003537.1_3 - 0.18 10.4 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Sigma NS protein Ribosomal_L11_N PF03946.14 AAAP01003537.1_4 - 1.6e-33 114.3 0.3 2.4e-33 113.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AAAP01003537.1_4 - 1.2e-05 25.8 1.1 1.4e-05 25.5 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Na_sulph_symp PF00939.19 AAAP01003538.1_1 - 1.3e-11 44.2 13.3 1.6e-11 44.0 13.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AAAP01003538.1_1 - 8.2e-11 41.6 26.9 1.5e-10 40.8 26.0 1.6 1 1 0 1 1 1 1 Citrate transporter DEAD PF00270.29 AAAP01003538.1_2 - 2.9e-47 160.7 0.0 8.9e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAAP01003538.1_2 - 1.5e-28 99.3 0.1 4.4e-28 97.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAAP01003538.1_2 - 5.2e-05 23.3 0.0 9.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AAAP01003538.1_2 - 0.0024 18.2 0.1 0.22 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 AAAP01003538.1_2 - 0.015 14.7 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 AAAP01003538.1_2 - 0.026 13.3 0.0 0.99 8.1 0.0 2.7 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 AAAP01003538.1_2 - 0.031 14.5 0.2 0.25 11.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain SUa-2TM PF18179.1 AAAP01003538.1_2 - 0.091 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain MAPEG PF01124.18 AAAP01003539.1_1 - 1e-24 86.9 9.9 1.2e-24 86.7 9.9 1.0 1 0 0 1 1 1 1 MAPEG family ABC_tran PF00005.27 AAAP01003539.1_2 - 1.6e-30 106.4 0.0 2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003539.1_2 - 1.7e-08 34.7 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003539.1_2 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003539.1_2 - 0.0019 18.6 0.6 0.005 17.2 0.6 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003539.1_2 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 AAAP01003539.1_2 - 0.0026 17.9 0.0 0.017 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003539.1_2 - 0.0056 17.0 0.1 0.051 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003539.1_2 - 0.031 13.7 0.0 7 6.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAAP01003539.1_2 - 0.035 13.7 0.7 0.083 12.5 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAAP01003539.1_2 - 0.038 14.5 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AAAP01003539.1_2 - 0.06 13.3 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 AAAP01003539.1_2 - 0.12 12.6 0.0 4.6 7.6 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MacB_PCD PF12704.7 AAAP01003539.1_3 - 8e-20 72.0 1.4 8e-20 72.0 1.4 1.9 3 0 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 AAAP01003539.1_3 - 1.3e-11 44.8 2.3 1.3e-11 44.8 2.3 3.1 3 0 0 3 3 3 1 FtsX-like permease family NPCC PF08058.11 AAAP01003539.1_3 - 0.078 13.0 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Nuclear pore complex component Molydop_binding PF01568.21 AAAP01003539.1_3 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain NadA PF02445.16 AAAP01003540.1_1 - 5.8e-06 25.7 0.1 6.4e-06 25.5 0.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein QRPTase_C PF01729.19 AAAP01003540.1_2 - 4e-57 192.7 0.1 5.3e-57 192.3 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AAAP01003540.1_2 - 2.1e-28 98.2 0.1 5.4e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.17 AAAP01003540.1_2 - 0.018 14.4 1.1 0.13 11.6 1.1 2.0 1 1 0 1 1 1 0 Thiamine monophosphate synthase Biotin_lipoyl PF00364.22 AAAP01003540.1_2 - 0.066 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme Ribul_P_3_epim PF00834.19 AAAP01003540.1_2 - 0.072 12.5 1.0 0.17 11.2 0.2 1.8 1 1 0 2 2 2 0 Ribulose-phosphate 3 epimerase family PHB_acc_N PF07879.11 AAAP01003540.1_2 - 0.28 11.3 0.4 26 5.0 0.0 2.7 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain FAD_binding_2 PF00890.24 AAAP01003540.1_3 - 4.6e-15 55.6 2.2 5.5e-15 55.4 2.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 AAAP01003540.1_3 - 5.9e-08 32.7 1.4 6.1e-08 32.6 1.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AAAP01003540.1_3 - 0.00044 19.5 0.2 0.00073 18.8 0.1 1.3 1 1 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 AAAP01003540.1_3 - 0.00083 18.5 0.6 0.0011 18.1 0.3 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AAAP01003540.1_3 - 0.00093 18.5 0.1 0.00098 18.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003540.1_3 - 0.011 14.5 0.1 0.011 14.5 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 AAAP01003540.1_3 - 0.015 15.5 0.3 0.023 14.9 0.2 1.4 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AAAP01003540.1_3 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sacchrp_dh_NADP PF03435.18 AAAP01003540.1_3 - 0.11 12.8 0.2 0.13 12.5 0.2 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 AAAP01003541.1_1 - 6e-10 39.0 0.0 6.8e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01003541.1_1 - 3.4e-08 33.6 0.1 3.8e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAAP01003541.1_1 - 3.3e-07 30.1 0.0 3.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 AAAP01003541.1_1 - 3.4e-05 23.0 0.0 4e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003541.1_1 - 0.00033 19.8 0.0 0.00036 19.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAAP01003541.1_1 - 0.00035 20.1 0.0 0.00043 19.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 AAAP01003541.1_1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AAAP01003541.1_1 - 0.015 14.5 0.1 0.065 12.4 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 AAAP01003541.1_1 - 0.028 13.5 0.7 0.39 9.8 0.7 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DFP PF04127.15 AAAP01003541.1_1 - 0.048 13.5 0.0 0.056 13.3 0.0 1.0 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein YscO PF07321.12 AAAP01003541.1_1 - 0.12 12.4 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Semialdhyde_dh PF01118.24 AAAP01003541.1_1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Transket_pyr PF02779.24 AAAP01003541.1_2 - 9.6e-36 123.1 0.3 1.4e-35 122.6 0.3 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAAP01003541.1_2 - 1.6e-28 99.0 0.1 2.7e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain AAA_23 PF13476.6 AAAP01003542.1_2 - 0.0099 16.4 6.2 0.084 13.4 6.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 AAAP01003542.1_2 - 0.028 13.1 4.8 1 7.9 6.2 2.2 1 1 1 2 2 2 0 AAA domain HMMR_N PF15905.5 AAAP01003542.1_2 - 0.036 13.5 3.8 0.054 13.0 3.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AAA_29 PF13555.6 AAAP01003542.1_2 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AAAP01003542.1_2 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 AAAP01003542.1_2 - 0.16 11.4 0.3 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAAP01003542.1_2 - 0.16 11.6 0.0 0.35 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01003542.1_2 - 0.17 12.2 0.3 0.55 10.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain UBN_AB PF14075.6 AAAP01003542.1_2 - 0.21 11.3 2.8 0.55 9.9 2.8 1.7 1 1 0 1 1 1 0 Ubinuclein conserved middle domain AAA_16 PF13191.6 AAAP01003542.1_2 - 0.36 11.2 10.3 13 6.1 10.3 2.6 1 1 0 1 1 1 0 AAA ATPase domain DUF2959 PF11172.8 AAAP01003542.1_2 - 0.92 9.6 9.3 0.93 9.6 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) APG6_N PF17675.1 AAAP01003542.1_2 - 2.2 8.8 11.1 1.5 9.3 9.0 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Glyoxalase PF00903.25 AAAP01003543.1_1 - 2.2e-06 27.9 0.0 3.1e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AAAP01003543.1_1 - 0.0002 22.1 0.0 0.00036 21.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain AHSA1 PF08327.11 AAAP01003543.1_2 - 1.2e-34 119.2 0.1 1.4e-34 119.0 0.1 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein OTCace_N PF02729.21 AAAP01003543.1_3 - 4.4e-49 166.3 0.2 6.2e-49 165.8 0.2 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AAAP01003543.1_3 - 9.6e-48 162.2 0.0 1.5e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain UPF0180 PF03698.13 AAAP01003543.1_3 - 0.21 11.8 0.2 0.7 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Aminotran_3 PF00202.21 AAAP01003543.1_4 - 1.2e-25 90.0 0.0 1.3e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ThiG PF05690.14 AAAP01003544.1_1 - 5.9e-109 363.1 0.4 7.9e-109 362.7 0.4 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG ThiS PF02597.20 AAAP01003544.1_1 - 7.6e-11 42.5 0.1 1.5e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 ThiS family His_biosynth PF00977.21 AAAP01003544.1_1 - 0.0005 19.6 0.5 0.0045 16.5 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AAAP01003544.1_1 - 0.0067 15.5 0.1 0.0093 15.0 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase SOR_SNZ PF01680.17 AAAP01003544.1_1 - 0.0091 15.8 0.4 0.018 14.8 0.4 1.5 1 0 0 1 1 1 1 SOR/SNZ family Dus PF01207.17 AAAP01003544.1_1 - 0.076 12.1 0.3 0.18 10.9 0.1 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF348 PF03990.14 AAAP01003544.1_1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.5 4 0 0 4 4 4 0 G5-linked-Ubiquitin-like domain DHquinase_II PF01220.19 AAAP01003544.1_2 - 5e-47 159.0 0.2 5.6e-47 158.9 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Competence PF03772.16 AAAP01003545.1_1 - 5.3e-62 209.6 31.6 5.3e-62 209.6 31.6 2.1 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 AAAP01003545.1_1 - 4.1e-13 49.3 5.9 4.1e-13 49.3 5.9 4.8 4 2 2 6 6 6 1 Domain of unknown function (DUF4131) tRNA-synt_1c PF00749.21 AAAP01003545.1_2 - 2.1e-73 247.0 0.0 2.4e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_His PF13393.6 AAAP01003546.1_1 - 9.1e-41 140.1 0.0 6.3e-25 88.1 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AAAP01003546.1_1 - 5e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 AAAP01003546.1_1 - 0.00062 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_bind PF01588.20 AAAP01003546.1_2 - 5.9e-13 48.7 0.0 6.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain DUF3429 PF11911.8 AAAP01003546.1_3 - 1.5e-18 67.5 16.2 1.7e-18 67.3 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) MFS_1 PF07690.16 AAAP01003546.1_4 - 3.9e-44 151.0 51.7 2.9e-33 115.3 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01003546.1_4 - 5.1e-18 65.1 3.6 1.5e-17 63.6 3.6 1.6 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 AAAP01003546.1_4 - 8.9e-05 21.5 3.9 8.9e-05 21.5 3.9 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 AAAP01003546.1_4 - 0.0002 20.8 34.2 0.0018 17.7 35.4 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 AAAP01003546.1_4 - 0.00097 17.7 0.7 0.00097 17.7 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 AAAP01003546.1_4 - 0.002 17.0 5.1 0.0095 14.7 5.1 2.0 1 1 0 1 1 1 1 LacY proton/sugar symporter HemY_N PF07219.13 AAAP01003546.1_4 - 0.024 14.8 2.0 0.024 14.8 2.0 3.0 2 1 1 3 3 3 0 HemY protein N-terminus DUF3087 PF11286.8 AAAP01003546.1_4 - 0.24 10.8 2.1 0.18 11.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) SecB PF02556.14 AAAP01003546.1_5 - 1.8e-53 180.2 0.2 2.2e-53 180.0 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB CBP_BcsN PF17038.5 AAAP01003547.1_1 - 8.6e-17 61.1 0.0 2.2e-16 59.8 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsN TPR_2 PF07719.17 AAAP01003547.1_2 - 9.8e-07 28.4 4.1 0.028 14.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003547.1_2 - 0.00021 21.5 5.7 7.8 6.9 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003547.1_2 - 0.0015 18.3 1.6 2.2 8.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003547.1_2 - 0.03 15.2 15.3 4.3 8.4 0.5 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003547.1_2 - 0.033 14.4 0.4 3.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 AAAP01003547.1_2 - 0.16 12.6 8.6 2.2 9.0 1.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 AAAP01003547.1_2 - 0.36 11.6 2.0 15 6.5 0.3 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_10 PF13374.6 AAAP01003547.1_2 - 1.3 9.0 6.2 6.1 6.9 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Radical_SAM PF04055.21 AAAP01003548.1_1 - 0.024 15.0 0.8 0.042 14.2 0.8 1.6 1 1 0 1 1 1 0 Radical SAM superfamily DUF1848 PF08902.11 AAAP01003548.1_1 - 0.18 11.5 1.1 0.25 11.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) PT-VENN PF04829.13 AAAP01003548.1_2 - 9.3 6.4 7.8 1.1 9.4 3.6 1.7 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif SpoIIIAC PF06686.11 AAAP01003548.1_3 - 0.28 11.4 3.2 0.46 10.7 3.2 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Ribosomal_L33 PF00471.20 AAAP01003548.1_4 - 2.2e-16 60.0 0.9 2.5e-16 59.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Pantoate_transf PF02548.15 AAAP01003548.1_5 - 4.2e-103 344.3 2.0 4.7e-103 344.1 2.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Thioredoxin PF00085.20 AAAP01003548.1_6 - 1.6e-10 40.8 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAAP01003548.1_6 - 2.1e-05 24.9 0.0 0.00031 21.2 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AAAP01003548.1_6 - 0.00022 21.4 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AAAP01003548.1_6 - 0.00096 18.9 0.0 0.0024 17.6 0.0 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01003548.1_6 - 0.0076 16.2 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.14 AAAP01003548.1_6 - 0.2 12.1 0.0 0.23 11.9 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Rhodanese PF00581.20 AAAP01003548.1_7 - 0.00025 21.5 0.0 0.00029 21.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Plug PF07715.15 AAAP01003549.1_1 - 3.2e-14 53.4 2.0 7.4e-14 52.2 2.0 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AAAP01003549.1_1 - 0.01 15.7 19.3 0.014 15.3 16.5 2.3 1 1 1 2 2 2 0 TonB dependent receptor HTH_IclR PF09339.10 AAAP01003549.1_2 - 1.3e-10 40.9 0.7 1.3e-10 40.9 0.7 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain IclR PF01614.18 AAAP01003549.1_2 - 9e-09 35.2 0.1 1.7e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator FecCD PF01032.18 AAAP01003549.1_3 - 4e-72 242.9 33.7 4.7e-72 242.6 33.7 1.0 1 0 0 1 1 1 1 FecCD transport family ACR_tran PF00873.19 AAAP01003550.1_1 - 1.2e-52 178.8 5.0 1.4e-52 178.6 5.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family THDPS_M PF14789.6 AAAP01003550.1_1 - 0.027 14.5 0.2 0.06 13.4 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle ACR_tran PF00873.19 AAAP01003550.1_2 - 2.2e-37 128.3 0.0 2.6e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family HlyD_3 PF13437.6 AAAP01003550.1_3 - 3.7e-09 37.2 0.7 2.3e-08 34.7 0.3 2.1 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003550.1_3 - 4.2e-09 35.9 0.1 7.5e-09 35.1 0.1 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003550.1_3 - 0.013 15.3 2.9 1.6 8.6 0.0 3.1 3 0 0 3 3 3 0 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003550.1_3 - 0.11 12.4 0.3 2.9 7.8 0.2 2.3 2 0 0 2 2 2 0 Biotin-requiring enzyme PS_Dcarbxylase PF02666.15 AAAP01003550.1_3 - 0.15 11.6 0.0 0.8 9.2 0.0 1.9 2 0 0 2 2 2 0 Phosphatidylserine decarboxylase Response_reg PF00072.24 AAAP01003551.1_1 - 4.1e-44 149.3 1.4 2e-25 89.1 0.7 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003551.1_1 - 6.6e-26 91.0 0.1 1.2e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 AAAP01003551.1_1 - 8.2e-12 45.2 0.9 4.1e-11 43.0 0.9 2.2 1 0 0 1 1 1 1 Hpt domain Response_reg PF00072.24 AAAP01003551.1_2 - 4.8e-24 84.7 0.0 7.8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAAP01003551.1_2 - 3.2e-11 43.3 0.0 4.7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AAAP01003551.1_2 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidohydro_1 PF01979.20 AAAP01003552.1_2 - 2.1e-53 181.8 0.0 2.5e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003552.1_2 - 4e-11 43.1 1.8 8e-09 35.5 0.6 2.2 2 0 0 2 2 2 2 Amidohydrolase family BPD_transp_2 PF02653.16 AAAP01003552.1_3 - 2.1e-33 115.6 41.2 2.7e-33 115.3 41.2 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF4167 PF13763.6 AAAP01003553.1_1 - 9.3e-30 102.6 0.0 9.3e-30 102.6 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4167) PrmC_N PF17827.1 AAAP01003553.1_2 - 2.6e-14 53.5 2.4 5.1e-14 52.6 2.4 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 AAAP01003553.1_2 - 1.2e-10 41.4 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003553.1_2 - 1.5e-08 34.4 0.0 2.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AAAP01003553.1_2 - 9.6e-07 28.5 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AAAP01003553.1_2 - 9e-06 26.3 0.0 2.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 AAAP01003553.1_2 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 AAAP01003553.1_2 - 0.012 16.2 0.1 0.037 14.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 AAAP01003553.1_2 - 0.028 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003553.1_2 - 0.045 13.6 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 AAAP01003553.1_2 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCRF PF03462.18 AAAP01003553.1_3 - 3.9e-65 219.3 0.2 6e-65 218.7 0.2 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 AAAP01003553.1_3 - 4.8e-41 139.3 1.0 1.2e-40 138.1 1.0 1.6 1 0 0 1 1 1 1 RF-1 domain MutS_III PF05192.18 AAAP01003553.1_3 - 0.49 10.6 2.6 0.82 9.9 2.6 1.6 1 1 0 1 1 1 0 MutS domain III PEP-utilizers_C PF02896.18 AAAP01003553.1_4 - 8.3e-28 97.3 0.0 1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Nitro_FeMo-Co PF02579.17 AAAP01003553.1_4 - 0.00024 21.4 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Aldedh PF00171.22 AAAP01003554.1_1 - 5.4e-54 183.4 0.0 6.4e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PHB_depo_C PF06850.11 AAAP01003554.1_2 - 2e-94 314.7 0.0 3.3e-94 314.0 0.0 1.3 1 0 0 1 1 1 1 PHB de-polymerase C-terminus DUF1072 PF06380.11 AAAP01003554.1_2 - 0.024 14.5 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) FAD_binding_4 PF01565.23 AAAP01003554.1_3 - 2.9e-39 134.0 0.1 5e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 AAAP01003554.1_3 - 7.3e-33 114.2 0.0 1.3e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Cytochrome_CBB3 PF13442.6 AAAP01003555.1_1 - 1.9e-12 47.3 0.0 3.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003555.1_1 - 7.7e-08 33.4 0.0 1.3e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c DUF3365 PF11845.8 AAAP01003555.1_2 - 0.17 12.2 0.0 0.65 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) HAMP PF00672.25 AAAP01003555.1_2 - 0.19 12.1 0.8 0.96 9.9 0.8 2.3 1 1 0 1 1 1 0 HAMP domain Fic PF02661.18 AAAP01003556.1_2 - 2.4e-08 34.7 0.1 6.2e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family Hexapep PF00132.24 AAAP01003557.1_2 - 2.3e-09 36.6 13.3 0.00049 19.7 0.2 5.4 5 1 0 6 6 6 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003557.1_2 - 0.0006 19.5 10.9 0.89 9.4 0.2 5.4 4 2 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase NMT1 PF09084.11 AAAP01003557.1_3 - 2.7e-12 47.1 0.0 3.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAAP01003557.1_3 - 6.8e-12 45.6 0.1 9.3e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01003557.1_3 - 1.2e-07 31.6 0.1 1.6e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAAP01003557.1_3 - 2e-07 30.7 0.0 2.5e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAAP01003557.1_3 - 0.00096 18.6 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 NMT1-like family DUF2680 PF10925.8 AAAP01003557.1_4 - 0.075 13.1 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Cupin_2 PF07883.11 AAAP01003557.1_5 - 1.9e-10 40.3 0.2 1.9e-10 40.3 0.2 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 AAAP01003557.1_5 - 2.1e-05 24.2 0.1 2.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 AAAP01003557.1_5 - 0.0096 15.8 0.0 0.0096 15.8 0.0 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain JmjC PF02373.22 AAAP01003557.1_5 - 0.012 16.1 0.1 0.064 13.7 0.1 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase DMSP_lyase PF16867.5 AAAP01003557.1_5 - 0.073 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase AraC_N PF06719.13 AAAP01003557.1_5 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus Rick_17kDa_Anti PF05433.15 AAAP01003557.1_6 - 0.011 15.6 10.3 0.033 14.0 10.3 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain Hydantoinase_B PF02538.14 AAAP01003558.1_2 - 3.3e-153 510.8 0.1 4.1e-153 510.5 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 AAAP01003558.1_3 - 2.4e-87 292.9 0.0 3e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 AAAP01003558.1_3 - 1.3e-21 77.1 0.0 3.4e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Pilus_CpaD PF09476.10 AAAP01003558.1_3 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pribosyltran PF00156.27 AAAP01003559.1_1 - 6.5e-10 38.7 0.1 8.8e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AAAP01003559.1_1 - 0.0054 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase Colicin_V PF02674.16 AAAP01003559.1_3 - 4.7e-30 104.5 13.2 5.7e-30 104.2 13.2 1.0 1 0 0 1 1 1 1 Colicin V production protein ChlI PF13541.6 AAAP01003559.1_4 - 2.6e-06 27.3 0.0 3e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 AAAP01003559.1_4 - 0.14 11.7 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain Erythro-docking PF09277.11 AAAP01003560.1_3 - 0.024 14.5 3.6 0.23 11.4 0.2 2.5 3 0 0 3 3 3 0 Erythronolide synthase, docking PSK_trans_fac PF07704.11 AAAP01003560.1_3 - 0.18 12.6 6.1 1.8 9.4 0.5 2.6 2 1 0 3 3 3 0 Rv0623-like transcription factor DUF826 PF05696.11 AAAP01003560.1_3 - 1.2 9.3 3.1 5 7.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF826) Hint_2 PF13403.6 AAAP01003560.1_4 - 1.7e-44 151.6 0.0 2.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Hint domain DUF2093 PF09866.9 AAAP01003560.1_4 - 0.17 11.3 0.1 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Voltage_CLC PF00654.20 AAAP01003561.1_1 - 2.5e-60 204.6 32.9 2.8e-60 204.5 32.9 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel HisKA PF00512.25 AAAP01003561.1_1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF1328 PF07043.13 AAAP01003561.1_2 - 2e-13 50.3 13.7 2e-13 50.3 13.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1328) DUF2975 PF11188.8 AAAP01003561.1_2 - 5.9 6.8 11.8 6 6.8 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) AIRS_C PF02769.22 AAAP01003561.1_3 - 3.3e-11 43.6 0.2 4.4e-11 43.2 0.2 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain HTH_31 PF13560.6 AAAP01003561.1_3 - 0.061 13.7 0.6 6.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain NusB PF01029.18 AAAP01003561.1_4 - 7.8e-29 100.6 0.0 9.5e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 NusB family DMRL_synthase PF00885.19 AAAP01003561.1_5 - 4.2e-43 146.5 0.8 4.8e-43 146.4 0.8 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HAD PF12710.7 AAAP01003561.1_6 - 1.2e-07 32.4 2.6 5.2e-06 27.0 2.6 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003561.1_6 - 0.00021 21.7 2.9 0.0094 16.3 0.7 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase UbiA PF01040.18 AAAP01003561.1_6 - 0.0004 19.8 0.2 0.00099 18.5 0.0 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family RICTOR_V PF14668.6 AAAP01003561.1_6 - 0.027 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 TonB_dep_Rec PF00593.24 AAAP01003562.1_1 - 2.3e-40 139.9 8.1 2.9e-40 139.5 8.1 1.0 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AAAP01003562.1_1 - 0.0095 15.0 0.0 0.11 11.5 0.2 2.0 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family DDE_3 PF13358.6 AAAP01003562.1_2 - 5.6e-23 81.3 0.0 8.9e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 AAAP01003562.1_2 - 5e-13 48.4 1.1 3.3e-10 39.5 0.2 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003562.1_2 - 8.4e-13 48.1 3.5 3.9e-12 46.0 0.2 2.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 AAAP01003562.1_2 - 1.4e-10 41.6 0.6 1.4e-10 41.6 0.6 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01003562.1_2 - 2.9e-10 40.1 1.9 1.4e-07 31.5 0.1 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_6 PF01418.17 AAAP01003562.1_2 - 5.6e-06 26.2 0.2 0.00013 21.8 0.0 2.9 4 0 0 4 4 3 1 Helix-turn-helix domain, rpiR family LZ_Tnp_IS481 PF13011.6 AAAP01003562.1_2 - 2e-05 25.0 1.5 3.9e-05 24.1 0.3 2.1 1 1 1 2 2 2 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 AAAP01003562.1_2 - 3.5e-05 24.0 0.6 0.00039 20.7 0.0 2.8 2 1 2 4 4 4 1 Transposase HTH_50 PF18024.1 AAAP01003562.1_2 - 0.00059 19.4 0.1 0.0083 15.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAAP01003562.1_2 - 0.0019 17.8 0.0 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.19 AAAP01003562.1_2 - 0.0048 16.4 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 AAAP01003562.1_2 - 0.0074 15.8 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 AAAP01003562.1_2 - 0.016 15.1 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR PF01047.22 AAAP01003562.1_2 - 0.023 14.6 0.1 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 MarR family HTH_AsnC-type PF13404.6 AAAP01003562.1_2 - 0.033 14.0 0.3 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Terminase_5 PF06056.12 AAAP01003562.1_2 - 0.035 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_31 PF13560.6 AAAP01003562.1_2 - 0.062 13.7 1.7 0.65 10.4 0.0 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01003562.1_2 - 0.073 13.1 0.6 4.3 7.4 0.1 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 AAAP01003562.1_2 - 0.16 12.1 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 AAAP01003562.1_2 - 0.22 11.3 3.1 6.2 6.7 0.1 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003563.1_2 - 1.7e-15 56.9 0.0 4.1e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 AAAP01003563.1_3 - 1e-20 73.6 0.0 1.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EAL PF00563.20 AAAP01003564.1_1 - 6.3e-14 52.1 0.0 7.4e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain CAP_N PF01213.19 AAAP01003564.1_1 - 1.8 7.9 3.2 2.2 7.7 3.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EutK_C PF16365.5 AAAP01003564.1_2 - 0.0086 16.1 0.2 0.017 15.1 0.2 1.6 1 0 0 1 1 1 1 Ethanolamine utilization protein EutK C-terminus CheZ PF04344.13 AAAP01003564.1_3 - 2e-11 44.2 0.1 7.4e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 Chemotaxis phosphatase, CheZ Hydant_A_N PF05378.13 AAAP01003564.1_3 - 0.08 12.6 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Response_reg PF00072.24 AAAP01003564.1_4 - 4.9e-29 100.8 0.0 6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain FAD_syn PF06574.12 AAAP01003564.1_5 - 9.2e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 FAD synthetase CTP_transf_like PF01467.26 AAAP01003564.1_5 - 0.019 15.1 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like RNA_pol_Rpb2_2 PF04561.14 AAAP01003565.1_1 - 1.2e-27 96.8 0.0 1.1e-20 74.1 0.0 2.5 2 1 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 AAAP01003565.1_1 - 1.2e-24 87.0 0.0 3.5e-24 85.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit Ribosomal_L12 PF00542.19 AAAP01003565.1_2 - 4.9e-30 103.7 10.7 4.9e-30 103.7 10.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AAAP01003565.1_2 - 1.3e-19 69.6 14.4 5.9e-18 64.3 11.3 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 AAAP01003565.1_2 - 1.3 9.7 18.7 4.3 8.0 10.3 2.7 1 1 2 3 3 3 0 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 AAAP01003565.1_3 - 1.4e-22 79.7 0.0 2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L1 PF00687.21 AAAP01003565.1_4 - 5.8e-57 192.7 0.0 6.4e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GAF PF01590.26 AAAP01003566.1_1 - 1.4e-14 54.9 0.0 2.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 AAAP01003566.1_1 - 6.5e-11 42.9 0.0 1.3e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold Exog_C PF18026.1 AAAP01003566.1_1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain EAL PF00563.20 AAAP01003566.1_2 - 8.5e-35 120.4 0.0 1.1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003566.1_3 - 1.4e-53 180.9 1.6 2.3e-53 180.3 0.4 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain EAL PF00563.20 AAAP01003566.1_3 - 1.2e-25 90.4 0.0 2.6e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 EAL domain PAS_9 PF13426.7 AAAP01003566.1_3 - 8.1e-21 74.2 0.2 3.5e-20 72.2 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003566.1_3 - 2.7e-13 49.9 0.0 5.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003566.1_3 - 3.1e-12 46.6 0.3 4.2e-11 43.0 0.1 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAAP01003566.1_3 - 2.2e-08 34.3 0.0 8.9e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003566.1_3 - 3.4e-06 26.9 0.0 1.2e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain MCPsignal PF00015.21 AAAP01003567.1_1 - 7e-60 201.8 100.1 9.4e-32 110.2 21.7 7.1 1 1 5 7 7 7 6 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003567.1_1 - 1.5 9.1 44.3 4 7.8 0.8 7.9 4 3 4 8 8 8 0 Bacterial protein of unknown function (DUF948) HTH_23 PF13384.6 AAAP01003567.1_2 - 1.9e-09 37.0 0.0 3.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01003567.1_2 - 4.9e-08 33.0 0.9 9.2e-08 32.1 0.1 1.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 AAAP01003567.1_2 - 5.5e-06 25.9 0.2 0.00017 21.2 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.6 AAAP01003567.1_2 - 2.3e-05 24.3 0.1 2.3e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_4 PF13613.6 AAAP01003567.1_2 - 0.002 17.8 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease PAX PF00292.18 AAAP01003567.1_2 - 0.0025 17.7 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 AAAP01003567.1_2 - 0.0034 18.0 0.0 0.0034 18.0 0.0 2.5 1 1 2 3 3 3 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 AAAP01003567.1_2 - 0.0052 17.3 0.2 0.0052 17.3 0.2 1.8 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_psq PF05225.16 AAAP01003567.1_2 - 0.0059 16.3 0.4 0.023 14.4 0.1 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF746 PF05344.11 AAAP01003567.1_2 - 0.008 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) HTH_Tnp_IS630 PF01710.16 AAAP01003567.1_2 - 0.019 15.0 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 Transposase Arg_repressor PF01316.21 AAAP01003567.1_2 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DDE_3 PF13358.6 AAAP01003567.1_3 - 4e-28 98.0 0.0 4.8e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 AAAP01003567.1_3 - 0.2 10.6 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Orn_Arg_deC_N PF02784.16 AAAP01003568.1_1 - 8.4e-46 156.3 0.0 1e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain UxaE PF16257.5 AAAP01003568.1_1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 tagaturonate epimerase Orn_DAP_Arg_deC PF00278.22 AAAP01003568.1_2 - 1.4e-09 38.1 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Acetyltransf_1 PF00583.25 AAAP01003568.1_3 - 2.3e-12 47.2 0.0 3.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003568.1_3 - 1.3e-10 41.6 0.0 1.8e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003568.1_3 - 1.4e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAAP01003568.1_3 - 4.4e-07 30.0 0.0 6.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01003568.1_3 - 0.0018 18.4 0.1 0.0034 17.5 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AAAP01003568.1_3 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.7 AAAP01003568.1_3 - 0.097 12.8 0.4 0.097 12.8 0.4 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain PP-binding PF00550.25 AAAP01003569.1_1 - 8.5e-08 32.4 0.2 9.2e-08 32.3 0.2 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 AAAP01003569.1_2 - 6.2e-64 215.7 9.9 7.1e-64 215.6 9.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003569.1_2 - 1.5e-57 194.2 3.1 2e-57 193.8 3.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003569.1_2 - 1.9e-20 73.6 2.4 2.6e-20 73.1 2.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003569.1_2 - 4.3e-05 23.5 3.8 5.6e-05 23.1 3.8 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAAP01003569.1_2 - 6.3e-05 22.6 0.9 0.00013 21.6 0.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AAAP01003569.1_2 - 0.009 16.6 1.1 6.5 7.4 0.7 2.4 2 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Seadorna_Vp10 PF07322.11 AAAP01003569.1_2 - 0.011 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 THF_DHG_CYH_C PF02882.19 AAAP01003569.1_2 - 0.012 14.9 0.4 0.055 12.8 0.0 2.2 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 AAAP01003569.1_2 - 0.079 12.5 1.5 0.091 12.3 0.7 1.5 2 0 0 2 2 2 0 NmrA-like family Ldh_1_N PF00056.23 AAAP01003569.1_2 - 0.2 11.7 5.0 0.082 13.0 0.7 2.3 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Acyl_transf_1 PF00698.21 AAAP01003569.1_3 - 1e-32 114.0 5.1 1.3e-32 113.6 5.1 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 AAAP01003569.1_3 - 0.38 10.5 4.9 6.1 6.5 0.0 2.4 1 1 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis HATPase_c PF02518.26 AAAP01003570.1_2 - 2.8e-17 63.2 0.0 3.1e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01003570.1_2 - 0.0019 18.0 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4915 PF16261.5 AAAP01003570.1_2 - 0.062 12.5 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4915) FAD_binding_4 PF01565.23 AAAP01003570.1_3 - 9.6e-06 25.4 4.3 0.00014 21.6 0.4 3.1 3 0 0 3 3 3 2 FAD binding domain NPA PF16469.5 AAAP01003570.1_4 - 0.042 14.4 0.0 0.08 13.5 0.0 1.4 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF202 PF02656.15 AAAP01003571.1_3 - 1.2 9.7 9.0 2.4 8.7 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) NDUF_B12 PF08122.12 AAAP01003571.1_3 - 2.3 8.3 4.8 29 4.8 0.5 2.8 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family CSD PF00313.22 AAAP01003572.1_2 - 1.8e-22 78.9 0.0 1.9e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01003572.1_2 - 0.00022 20.9 0.1 0.00036 20.2 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain RNase_T PF00929.24 AAAP01003572.1_3 - 1.5e-21 77.6 0.0 2.1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease SLT PF01464.20 AAAP01003573.1_2 - 2.2e-10 40.2 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain CusF_Ec PF11604.8 AAAP01003573.1_3 - 5.3e-26 90.4 1.0 8.8e-26 89.7 1.0 1.4 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF DUF305 PF03713.13 AAAP01003573.1_3 - 4.1e-13 49.7 1.8 1.8e-06 28.2 0.0 1.6 1 1 1 2 2 2 2 Domain of unknown function (DUF305) PCB_OB PF17092.5 AAAP01003573.1_3 - 0.023 15.5 0.2 0.052 14.3 0.2 1.6 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain DUF1344 PF07076.11 AAAP01003573.1_3 - 0.049 13.5 0.5 1.8 8.5 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1344) Cu-oxidase_3 PF07732.15 AAAP01003573.1_4 - 6.6e-40 135.8 4.1 2.1e-35 121.3 0.1 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AAAP01003573.1_4 - 7.5e-28 97.0 10.0 1.8e-21 76.3 4.2 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 AAAP01003573.1_4 - 2.2e-05 24.6 0.1 4.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cys_Met_Meta_PP PF01053.20 AAAP01003574.1_1 - 9.6e-25 86.9 0.2 1e-24 86.8 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01003574.1_1 - 0.0023 17.3 0.1 0.0027 17.1 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family LEA_5 PF00477.17 AAAP01003574.1_1 - 0.067 13.6 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Rhodanese PF00581.20 AAAP01003574.1_2 - 4.7e-08 33.5 0.0 6.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_5 PF00266.19 AAAP01003574.1_4 - 6.6e-19 68.1 0.0 8.1e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_5 PF00266.19 AAAP01003574.1_5 - 7.9e-54 183.0 0.0 9.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 AAAP01003574.1_5 - 0.0098 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.21 AAAP01003574.1_5 - 0.015 14.6 1.0 0.065 12.5 0.7 2.0 2 1 0 2 2 2 0 Beta-eliminating lyase Acetyltransf_3 PF13302.7 AAAP01003574.1_6 - 4.5e-09 37.1 0.0 5.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CsbD PF05532.12 AAAP01003574.1_7 - 7.3e-18 64.2 13.5 7.9e-18 64.1 13.5 1.0 1 0 0 1 1 1 1 CsbD-like Acetyltransf_3 PF13302.7 AAAP01003574.1_8 - 2.9e-10 40.9 0.0 3.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAAP01003574.1_8 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MaoC_dehydratas PF01575.19 AAAP01003574.1_9 - 3.1e-17 62.3 0.0 3.9e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MobA_MobL PF03389.15 AAAP01003575.1_1 - 6.8e-09 35.8 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 MobA/MobL family BON PF04972.17 AAAP01003576.1_2 - 2.8e-10 40.4 1.8 5.1e-07 29.9 1.5 2.4 2 1 0 2 2 2 2 BON domain SPOR PF05036.13 AAAP01003576.1_2 - 0.01 16.2 0.4 0.076 13.4 0.2 2.1 2 0 0 2 2 2 0 Sporulation related domain HTH_11 PF08279.12 AAAP01003576.1_3 - 1.9e-06 27.7 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.16 AAAP01003576.1_3 - 0.00092 18.7 0.0 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 AAAP01003576.1_3 - 0.0051 16.3 1.4 0.0064 16.0 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAAP01003576.1_3 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HTH_23 PF13384.6 AAAP01003576.1_3 - 0.0075 16.0 0.4 0.043 13.6 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAAP01003576.1_3 - 0.028 14.3 2.7 0.032 14.1 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain UPF0122 PF04297.14 AAAP01003576.1_3 - 0.034 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_WhiA PF02650.14 AAAP01003576.1_3 - 0.046 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain HTH_IclR PF09339.10 AAAP01003576.1_3 - 0.054 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_18 PF12833.7 AAAP01003576.1_3 - 0.57 10.5 3.6 1.3 9.4 0.6 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_32 PF13565.6 AAAP01003576.1_3 - 8.2 7.1 7.9 9.4 6.9 0.1 3.1 3 1 1 4 4 4 0 Homeodomain-like domain SPDY PF03771.16 AAAP01003576.1_4 - 0.018 14.9 0.5 5.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF317) OrfB_Zn_ribbon PF07282.11 AAAP01003576.1_5 - 0.001 19.0 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain FUSC PF04632.12 AAAP01003576.1_5 - 0.005 15.4 0.3 0.0052 15.4 0.3 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Zn-ribbon_8 PF09723.10 AAAP01003576.1_5 - 0.023 14.8 2.3 0.85 9.8 0.1 2.8 3 0 0 3 3 3 0 Zinc ribbon domain Nudix_N_2 PF14803.6 AAAP01003576.1_5 - 0.034 14.1 1.2 0.14 12.1 0.8 2.0 1 1 1 2 2 2 0 Nudix N-terminal DUF1451 PF07295.11 AAAP01003576.1_5 - 0.066 13.2 2.0 0.14 12.1 2.0 1.6 1 1 0 1 1 1 0 Zinc-ribbon containing domain IFT57 PF10498.9 AAAP01003576.1_5 - 0.076 12.0 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PhnA_Zn_Ribbon PF08274.12 AAAP01003576.1_5 - 0.09 12.7 0.5 0.15 12.0 0.5 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AAAP01003576.1_5 - 0.17 11.4 2.5 9.4 5.9 0.1 2.2 1 1 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 AAAP01003576.1_5 - 0.21 11.3 2.0 0.79 9.5 2.0 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.13 AAAP01003576.1_5 - 0.34 10.6 1.4 0.69 9.6 1.4 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_recom PF13408.6 AAAP01003576.1_5 - 0.45 11.1 2.6 3.6 8.2 0.3 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Arm-DNA-bind_3 PF13356.6 AAAP01003576.1_6 - 9e-18 64.4 0.1 1.1e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 Arm DNA-binding domain AP2 PF00847.20 AAAP01003576.1_6 - 0.045 14.0 0.2 0.069 13.4 0.2 1.4 1 0 0 1 1 1 0 AP2 domain HATPase_c PF02518.26 AAAP01003577.1_1 - 3.3e-28 98.4 0.0 1.4e-27 96.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003577.1_1 - 5.2e-27 94.2 0.2 2.8e-26 91.9 0.0 2.2 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003577.1_1 - 1.5e-19 69.8 0.2 4.7e-19 68.2 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAAP01003577.1_1 - 8.1e-05 22.8 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Hpt domain HATPase_c_3 PF13589.6 AAAP01003577.1_1 - 0.0082 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003577.1_1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AAAP01003577.1_2 - 1.2e-27 96.3 0.1 1.3e-27 96.1 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CbiJ PF02571.14 AAAP01003577.1_3 - 9.1e-19 67.9 0.1 1e-18 67.7 0.1 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK GARS_N PF02844.15 AAAP01003577.1_3 - 0.14 12.9 0.0 0.19 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NIR_SIR PF01077.22 AAAP01003578.1_1 - 1.7e-24 86.2 0.0 2.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01003578.1_1 - 1.8e-15 56.5 0.0 6.9e-14 51.4 0.0 2.3 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rhodanese PF00581.20 AAAP01003578.1_2 - 2.1e-09 37.9 0.0 4e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain YkuD PF03734.14 AAAP01003578.1_3 - 3.4e-29 102.1 0.0 5.7e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 AAAP01003578.1_3 - 2.7e-07 30.7 0.0 8e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Putative peptidoglycan binding domain adh_short_C2 PF13561.6 AAAP01003579.1_1 - 6.4e-36 124.1 4.4 7e-36 123.9 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003579.1_1 - 3e-16 59.5 0.2 3.8e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase CBP_BcsS PF17036.5 AAAP01003579.1_2 - 2.7e-38 131.2 4.5 4.4e-38 130.4 4.2 1.5 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsS ExoD PF06055.12 AAAP01003579.1_3 - 1.3e-48 164.8 14.5 1.7e-48 164.4 14.5 1.1 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD ABC-3 PF00950.17 AAAP01003579.1_4 - 2.4e-48 164.9 27.4 2.8e-48 164.7 27.4 1.0 1 0 0 1 1 1 1 ABC 3 transport family VMA21 PF09446.10 AAAP01003579.1_4 - 0.28 11.3 6.6 4.7 7.4 0.0 3.4 3 0 0 3 3 3 0 VMA21-like domain Leu_Phe_trans PF03588.14 AAAP01003580.1_1 - 3.6e-68 228.3 0.0 4.4e-68 228.1 0.0 1.1 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 AAAP01003580.1_1 - 0.00093 19.4 0.6 0.003 17.7 0.6 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Hemerythrin PF01814.23 AAAP01003580.1_2 - 1e-11 45.6 2.1 1.3e-11 45.2 2.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NAPRTase PF04095.16 AAAP01003580.1_3 - 4.6e-64 216.3 0.0 5.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 AAAP01003580.1_3 - 8.4e-23 80.7 0.0 1.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) Tn7_Tnp_TnsA_N PF08722.11 AAAP01003581.1_1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 TnsA endonuclease N terminal rve PF00665.26 AAAP01003581.1_2 - 1.8e-21 76.6 0.0 3.3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AAAP01003581.1_2 - 1.4e-07 31.4 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Mu transposase, C-terminal TniB PF05621.11 AAAP01003581.1_3 - 4.8e-20 71.8 0.0 5.7e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AAAP01003581.1_3 - 6.9e-15 55.5 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003581.1_3 - 2.5e-05 24.8 0.5 0.00016 22.1 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAAP01003581.1_3 - 5.2e-05 22.9 0.4 0.00092 18.8 0.4 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AAAP01003581.1_3 - 0.00017 21.4 0.0 0.00018 21.2 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain NB-ARC PF00931.22 AAAP01003581.1_3 - 0.00053 19.3 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 AAAP01003581.1_3 - 0.0011 18.8 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003581.1_3 - 0.0039 17.6 0.0 0.0062 17.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AAAP01003581.1_3 - 0.0041 16.9 0.5 0.081 12.6 0.5 2.1 1 1 0 1 1 1 1 IstB-like ATP binding protein APS_kinase PF01583.20 AAAP01003581.1_3 - 0.0042 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.6 AAAP01003581.1_3 - 0.013 15.2 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAAP01003581.1_3 - 0.014 15.6 0.3 0.022 14.9 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003581.1_3 - 0.015 15.9 0.1 0.019 15.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003581.1_3 - 0.045 14.3 0.6 0.11 13.1 0.2 1.7 1 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 AAAP01003581.1_3 - 0.047 13.7 0.1 0.3 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AAAP01003581.1_3 - 0.057 12.7 0.0 0.086 12.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 AAAP01003581.1_3 - 0.093 12.8 0.3 1.1 9.4 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01003581.1_3 - 0.2 11.1 0.2 1.1 8.7 0.0 1.9 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 AAAP01003581.1_3 - 0.21 11.9 1.1 1.2 9.4 1.1 2.0 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 AAAP01003581.1_3 - 0.46 10.2 1.6 1.7 8.4 0.2 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase Glyco_tranf_2_3 PF13641.6 AAAP01003582.1_1 - 3.2e-27 95.9 0.0 5.6e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AAAP01003582.1_1 - 7.5e-27 94.2 0.0 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAAP01003582.1_1 - 1.6e-12 47.7 0.1 1.6e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_17 PF00332.18 AAAP01003582.1_1 - 1.2e-07 31.6 0.1 1.9e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_transf_21 PF13506.6 AAAP01003582.1_1 - 1.7e-06 27.7 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Gp_dh_C PF02800.20 AAAP01003582.1_1 - 0.23 11.0 0.1 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain NiFeSe_Hases PF00374.19 AAAP01003583.1_2 - 1.1e-207 691.0 0.0 1.2e-207 690.8 0.0 1.0 1 0 0 1 1 1 1 Nickel-dependent hydrogenase HycI PF01750.18 AAAP01003583.1_3 - 4.9e-21 74.9 0.0 5.9e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease ZT_dimer PF16916.5 AAAP01003584.1_1 - 1.5e-10 41.1 0.1 1.9e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Acyl_CoA_thio PF02551.15 AAAP01003584.1_1 - 0.041 13.7 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA thioesterase FUR PF01475.19 AAAP01003584.1_3 - 1e-39 135.4 0.2 1.2e-39 135.1 0.2 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family RepL PF05732.11 AAAP01003584.1_3 - 0.0056 16.1 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 2 Firmicute plasmid replication protein (RepL) MerR-DNA-bind PF09278.11 AAAP01003584.1_4 - 9.1e-21 74.2 3.0 1.5e-20 73.5 3.0 1.4 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAAP01003584.1_4 - 3.3e-19 68.7 0.0 5.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003584.1_4 - 1e-13 50.8 0.2 2e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 MerR family regulatory protein E1-E2_ATPase PF00122.20 AAAP01003584.1_5 - 3.4e-46 157.0 0.8 3.4e-46 157.0 0.8 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01003584.1_5 - 0.0038 17.5 0.1 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_2_2 PF10746.9 AAAP01003584.1_5 - 6.6 6.5 5.6 26 4.6 0.6 2.9 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II GrpE PF01025.19 AAAP01003585.1_1 - 1.4e-50 171.2 0.1 1.7e-50 171.0 0.1 1.1 1 0 0 1 1 1 1 GrpE ATG_C PF09333.11 AAAP01003585.1_1 - 0.078 13.3 0.5 1.6 9.2 0.0 2.7 2 1 1 3 3 3 0 Autophagy-related protein C terminal domain Dimerisation2 PF16864.5 AAAP01003585.1_1 - 0.12 12.3 0.3 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Dimerisation domain ACT PF01842.25 AAAP01003585.1_2 - 1.8e-14 53.2 0.4 7.2e-07 28.9 0.1 2.9 2 0 0 2 2 2 2 ACT domain HD PF01966.22 AAAP01003585.1_2 - 1e-12 48.3 1.1 2.5e-12 47.1 1.1 1.7 1 0 0 1 1 1 1 HD domain ACT_6 PF13740.6 AAAP01003585.1_2 - 3.1e-08 33.5 0.2 0.00063 19.7 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 AAAP01003585.1_2 - 3.6e-06 27.5 0.1 0.04 14.5 0.0 2.9 3 0 0 3 3 3 2 ACT domain NMT1 PF09084.11 AAAP01003585.1_4 - 2.9e-29 102.5 0.0 4.1e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAAP01003585.1_4 - 1.3e-09 38.2 0.2 8.7e-09 35.4 0.2 2.0 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAAP01003585.1_4 - 4.4e-08 32.8 0.0 7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAAP01003585.1_4 - 1.4e-06 28.1 0.1 1.9e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 AAAP01003585.1_4 - 2.8e-05 23.7 0.0 6.8e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 NMT1-like family BPD_transp_1 PF00528.22 AAAP01003585.1_5 - 7.3e-07 29.1 4.8 1.3e-06 28.2 4.8 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF543 PF04418.12 AAAP01003585.1_5 - 3 7.9 6.5 4.8 7.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DsrH PF04077.12 AAAP01003586.1_1 - 1e-26 92.8 0.0 1.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 DsrH like protein DsrC PF04358.13 AAAP01003586.1_2 - 1.1e-46 157.7 0.0 1.2e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein PC4 PF02229.16 AAAP01003586.1_2 - 0.12 12.1 0.8 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) Nitrate_red_gam PF02665.14 AAAP01003586.1_3 - 2.6e-14 53.3 11.3 3.5e-13 49.6 11.3 2.2 1 1 0 1 1 1 1 Nitrate reductase gamma subunit Fer4_8 PF13183.6 AAAP01003586.1_4 - 1.6e-09 38.1 2.2 3.3e-09 37.1 2.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003586.1_4 - 2e-09 37.9 2.3 4.2e-09 36.8 2.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003586.1_4 - 5.6e-06 26.4 3.6 0.018 15.2 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003586.1_4 - 1.3e-05 25.7 4.0 7.2e-05 23.3 4.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003586.1_4 - 0.00061 19.9 10.4 0.053 13.7 12.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003586.1_4 - 0.00069 19.6 9.4 0.11 12.6 1.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003586.1_4 - 0.0016 18.2 12.3 0.19 11.6 4.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003586.1_4 - 0.0069 17.3 7.8 0.17 12.8 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAAP01003586.1_4 - 0.0096 16.4 11.6 0.45 11.2 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003586.1_4 - 0.011 15.9 2.7 0.51 10.6 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003586.1_4 - 0.016 15.3 12.2 0.3 11.2 2.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAAP01003586.1_4 - 0.054 14.3 4.0 2.8 8.9 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003586.1_4 - 0.11 12.6 6.8 3.1 8.0 0.8 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003586.1_4 - 9.4 7.4 15.6 2.3 9.3 3.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain LysR_substrate PF03466.20 AAAP01003587.1_1 - 4.7e-38 130.7 4.0 7e-38 130.1 4.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003587.1_1 - 1.3e-07 31.4 1.8 3.2e-07 30.2 0.5 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 AAAP01003587.1_1 - 0.00026 20.8 0.0 0.47 10.2 0.0 2.2 1 1 0 2 2 2 2 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAAP01003587.1_1 - 0.041 13.0 0.1 0.097 11.8 0.1 1.5 2 0 0 2 2 2 0 PBP superfamily domain Nramp PF01566.18 AAAP01003587.1_2 - 7.5e-136 452.8 27.7 9.2e-136 452.5 27.7 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Fe_dep_repress PF01325.19 AAAP01003587.1_3 - 3.2e-14 52.9 0.0 4.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 AAAP01003587.1_3 - 6.8e-14 51.7 0.8 1.5e-13 50.7 0.8 1.5 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain MarR_2 PF12802.7 AAAP01003587.1_3 - 3.4e-08 33.3 0.1 9.7e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAAP01003587.1_3 - 9.9e-07 28.6 0.1 1e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAAP01003587.1_3 - 1.7e-06 27.5 0.0 3.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAAP01003587.1_3 - 1.9e-06 27.7 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 MarR family GntR PF00392.21 AAAP01003587.1_3 - 2.5e-06 27.0 0.8 3.3e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 AAAP01003587.1_3 - 5.8e-06 26.0 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_DeoR PF08220.12 AAAP01003587.1_3 - 2.5e-05 23.9 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 AAAP01003587.1_3 - 3.1e-05 23.6 4.3 0.00019 21.1 0.1 3.0 3 1 1 4 4 3 1 Homeodomain-like domain TrmB PF01978.19 AAAP01003587.1_3 - 6.4e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 AAAP01003587.1_3 - 0.00047 20.2 0.9 0.004 17.2 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_27 PF13463.6 AAAP01003587.1_3 - 0.00052 20.4 0.0 0.00087 19.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 AAAP01003587.1_3 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 AAAP01003587.1_3 - 0.002 18.1 0.1 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_1 PF00126.27 AAAP01003587.1_3 - 0.0041 17.0 0.2 0.017 15.1 0.2 2.0 1 1 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HemN_C PF06969.16 AAAP01003587.1_3 - 0.0041 17.1 0.4 0.032 14.3 0.0 2.4 3 0 0 3 3 3 1 HemN C-terminal domain HTH_AsnC-type PF13404.6 AAAP01003587.1_3 - 0.0066 16.3 0.9 0.063 13.1 0.1 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 AAAP01003587.1_3 - 0.0069 16.3 0.0 0.057 13.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 AAAP01003587.1_3 - 0.008 16.5 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 AAAP01003587.1_3 - 0.01 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 AAAP01003587.1_3 - 0.012 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit DUF5596 PF18082.1 AAAP01003587.1_3 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Crp PF00325.20 AAAP01003587.1_3 - 0.02 14.6 3.8 0.051 13.2 0.0 2.6 3 0 0 3 3 2 0 Bacterial regulatory proteins, crp family HxlR PF01638.17 AAAP01003587.1_3 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 1 0 1 1 1 0 HxlR-like helix-turn-helix HTH_11 PF08279.12 AAAP01003587.1_3 - 0.035 14.1 0.0 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_38 PF13936.6 AAAP01003587.1_3 - 0.048 13.4 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01003587.1_3 - 0.054 13.4 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 AAAP01003587.1_3 - 0.093 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix CtsR_C PF17727.1 AAAP01003587.1_3 - 0.097 12.8 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain HTH_47 PF16221.5 AAAP01003587.1_3 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 winged helix-turn-helix BCDHK_Adom3 PF10436.9 AAAP01003587.1_4 - 0.0074 16.1 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3517 PF12030.8 AAAP01003587.1_4 - 0.031 13.2 0.1 0.038 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Fer4_5 PF12801.7 AAAP01003588.1_1 - 3.8e-09 36.3 6.6 3.8e-09 36.3 6.6 4.2 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003588.1_1 - 2.2e-08 34.1 10.5 6.2e-08 32.6 9.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003588.1_1 - 1.1e-05 25.6 10.7 1.1e-05 25.6 10.7 2.1 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003588.1_1 - 1.3e-05 25.0 17.5 0.0044 17.0 2.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003588.1_1 - 5e-05 23.8 13.4 6.5e-05 23.4 11.2 2.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003588.1_1 - 9e-05 22.1 22.4 0.0051 16.6 3.5 3.9 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003588.1_1 - 0.00019 21.6 6.4 0.0016 18.6 5.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003588.1_1 - 0.0006 19.9 9.7 0.0006 19.9 9.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain EamA PF00892.20 AAAP01003588.1_1 - 0.0077 16.4 1.3 0.0077 16.4 1.3 2.5 3 0 0 3 3 2 1 EamA-like transporter family FpoO PF10621.9 AAAP01003588.1_1 - 0.025 14.9 2.2 0.047 14.0 2.2 1.4 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Fer4_8 PF13183.6 AAAP01003588.1_1 - 0.026 15.0 15.2 6.6 7.3 12.8 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003588.1_1 - 0.034 14.7 16.6 1.6 9.3 3.2 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003588.1_1 - 0.082 13.5 0.8 0.082 13.5 0.8 3.6 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003588.1_1 - 3 8.8 18.8 0.69 10.9 1.8 3.7 5 0 0 5 5 3 0 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 AAAP01003588.1_1 - 5.6 7.6 12.1 4.5 7.9 2.0 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I HGD-D PF06050.13 AAAP01003588.1_2 - 5.8e-69 233.3 0.1 6.9e-69 233.1 0.1 1.1 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Amidase PF01425.21 AAAP01003588.1_2 - 0.16 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Amidase BcrAD_BadFG PF01869.20 AAAP01003588.1_3 - 3.8e-51 174.1 8.6 4.3e-51 174.0 8.6 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 AAAP01003588.1_3 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pan_kinase PF03309.14 AAAP01003588.1_3 - 0.031 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase DsbD_2 PF13386.6 AAAP01003588.1_4 - 7.7e-08 32.5 8.5 8.6e-08 32.3 8.5 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region HTH_Crp_2 PF13545.6 AAAP01003590.1_1 - 5.7e-07 29.4 0.1 6.8e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003590.1_1 - 0.015 14.9 0.1 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family PAS_3 PF08447.12 AAAP01003590.1_2 - 5.8e-32 109.8 0.3 1e-14 54.6 0.0 2.9 4 0 0 4 4 2 2 PAS fold GerE PF00196.19 AAAP01003590.1_2 - 3.3e-16 58.6 0.0 6.2e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAAP01003590.1_2 - 4.2e-14 52.6 0.0 1.4e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 AAAP01003590.1_2 - 1.5e-11 44.5 8.4 0.0018 18.5 0.1 3.9 4 0 0 4 4 4 3 PAS fold GAF_2 PF13185.6 AAAP01003590.1_2 - 1.8e-09 38.0 0.2 1.2e-08 35.3 0.0 2.6 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 AAAP01003590.1_2 - 2.8e-08 34.5 0.0 6.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 AAAP01003590.1_2 - 1.9e-07 31.0 0.1 0.00084 19.3 0.0 3.2 3 0 0 3 3 3 2 PAS fold Sigma70_r4_2 PF08281.12 AAAP01003590.1_2 - 0.00028 20.5 0.1 0.00069 19.2 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 PAS_9 PF13426.7 AAAP01003590.1_2 - 0.0045 17.2 0.0 0.87 9.9 0.0 3.2 3 0 0 3 3 3 1 PAS domain HTH_23 PF13384.6 AAAP01003590.1_2 - 0.0073 16.1 0.2 0.027 14.2 0.2 2.1 1 0 0 1 1 1 1 Homeodomain-like domain FleQ PF06490.11 AAAP01003590.1_2 - 0.057 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Sigma70_r4 PF04545.16 AAAP01003590.1_2 - 0.071 12.6 0.1 0.2 11.2 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 AAAP01003590.1_2 - 0.74 9.6 4.4 0.38 10.5 0.2 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_Tnp_1 PF01609.21 AAAP01003590.1_3 - 1.3e-12 47.8 6.0 8.2e-12 45.2 6.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAAP01003590.1_3 - 2.7e-10 40.5 6.1 5.6e-10 39.5 6.1 1.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003590.1_3 - 0.0004 20.1 0.0 0.00046 19.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DEDD_Tnp_IS110 PF01548.17 AAAP01003590.1_4 - 9e-15 54.9 0.0 2.3e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Transposase Glyco_transf_5 PF08323.11 AAAP01003590.1_4 - 0.054 13.2 0.1 0.071 12.8 0.1 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain OmpA PF00691.20 AAAP01003591.1_2 - 5.7e-27 93.9 1.4 3.5e-15 56.1 0.2 2.5 2 0 0 2 2 2 2 OmpA family LPAM_1 PF08139.12 AAAP01003591.1_2 - 0.015 15.8 2.6 0.033 14.7 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Abhydrolase_5 PF12695.7 AAAP01003591.1_4 - 0.27 11.0 0.0 0.73 9.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family PAS_9 PF13426.7 AAAP01003592.1_1 - 1.3e-26 92.9 0.0 3.2e-20 72.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.26 AAAP01003592.1_1 - 1.2e-25 90.2 0.0 2.3e-24 86.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01003592.1_1 - 7.2e-18 64.6 0.0 3.1e-16 59.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAAP01003592.1_1 - 1e-17 64.2 1.5 1.6e-10 41.1 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AAAP01003592.1_1 - 4.5e-15 55.8 0.0 3.4e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 AAAP01003592.1_1 - 1.4e-12 47.4 0.0 2.9e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003592.1_1 - 1e-07 31.8 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AAAP01003592.1_1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 GHKL domain E2F_CC-MB PF16421.5 AAAP01003592.1_1 - 0.073 13.4 1.0 0.15 12.4 0.2 1.9 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain PAS_12 PF18095.1 AAAP01003592.1_1 - 0.079 12.6 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain PAS_2 PF08446.11 AAAP01003592.1_2 - 1.2e-10 42.0 0.0 5.4e-10 39.9 0.0 2.1 2 1 0 2 2 2 1 PAS fold DUF1849 PF08904.11 AAAP01003593.1_1 - 1.1e-35 123.4 0.0 1.2e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1849) TPR_12 PF13424.6 AAAP01003593.1_2 - 2.8e-05 24.3 18.5 0.25 11.7 2.9 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003593.1_2 - 0.00023 21.0 1.4 29 5.1 0.0 6.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003593.1_2 - 0.0024 17.8 1.4 6.7 7.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003593.1_2 - 0.0025 17.6 7.4 0.54 10.2 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF4824 PF16106.5 AAAP01003593.1_2 - 0.0083 15.4 0.2 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4824) TPR_6 PF13174.6 AAAP01003593.1_2 - 0.046 14.4 1.5 67 4.4 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003593.1_2 - 0.061 13.6 0.0 33 5.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003593.1_2 - 1.1 10.2 23.9 19 6.4 0.1 7.6 6 3 2 8 8 8 0 Tetratricopeptide repeat GGDEF PF00990.21 AAAP01003593.1_3 - 3.8e-41 140.5 0.0 5.2e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAAP01003593.1_3 - 5.2e-13 49.1 0.0 8.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain IMS PF00817.20 AAAP01003593.1_3 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family TPP_enzyme_N PF02776.18 AAAP01003594.1_2 - 7.6e-49 165.6 7.5 1.5e-47 161.4 0.3 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AAAP01003594.1_2 - 6e-26 91.1 0.9 1.2e-25 90.1 0.0 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAAP01003594.1_2 - 9.8e-16 57.7 0.1 4.8e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Iso_dh PF00180.20 AAAP01003594.1_5 - 4.5e-55 187.2 0.0 5.3e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Exonuc_VII_S PF02609.16 AAAP01003595.1_1 - 7e-17 61.2 2.4 8.4e-17 61.0 2.4 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit Vps53_N PF04100.12 AAAP01003595.1_1 - 0.017 14.1 0.1 0.019 14.0 0.1 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal Cast PF10174.9 AAAP01003595.1_1 - 0.045 12.0 0.3 0.051 11.8 0.3 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Ribosom_S30AE_C PF16321.5 AAAP01003595.1_1 - 0.12 12.1 0.5 0.19 11.4 0.1 1.5 2 0 0 2 2 2 0 Sigma 54 modulation/S30EA ribosomal protein C terminus TPR_16 PF13432.6 AAAP01003595.1_2 - 2.3e-10 41.0 11.6 1.1e-07 32.4 4.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003595.1_2 - 7.6e-09 36.0 6.0 0.00049 20.6 1.3 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003595.1_2 - 2.7e-08 34.0 8.8 0.026 15.3 0.2 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003595.1_2 - 3.1e-08 33.1 2.7 0.0064 16.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003595.1_2 - 3.3e-07 30.0 0.0 0.15 12.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003595.1_2 - 7.6e-07 28.7 0.2 0.031 14.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003595.1_2 - 1.5e-06 28.2 0.0 0.0081 16.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003595.1_2 - 2e-06 28.0 3.0 0.0026 18.0 0.2 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003595.1_2 - 0.00014 21.5 2.2 0.11 12.2 0.0 2.7 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 AAAP01003595.1_2 - 0.00042 20.4 6.8 0.011 15.9 2.8 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003595.1_2 - 0.0022 18.5 5.5 1.7 9.4 0.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AAAP01003595.1_2 - 0.0071 15.8 0.0 0.38 10.1 0.0 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_7 PF13176.6 AAAP01003595.1_2 - 0.0078 16.2 0.2 30 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003595.1_2 - 0.016 15.8 9.6 0.16 12.7 0.5 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003595.1_2 - 0.018 14.9 4.2 4.8 7.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2478 PF10649.9 AAAP01003595.1_2 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) Hist_deacetyl PF00850.19 AAAP01003595.1_4 - 2.8e-13 50.0 0.0 2.8e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF4013 PF13197.6 AAAP01003596.1_3 - 0.27 11.1 7.2 0.49 10.2 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) MFS_1 PF07690.16 AAAP01003597.1_1 - 6.9e-11 41.7 26.7 2.5e-10 39.8 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_2 PF13670.6 AAAP01003597.1_3 - 0.049 13.6 0.5 0.064 13.3 0.5 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Zn_Tnp_IS1595 PF12760.7 AAAP01003597.1_4 - 0.0021 18.0 2.8 0.0021 18.0 2.8 2.1 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DUF35_N PF12172.8 AAAP01003597.1_4 - 0.03 14.2 10.5 0.17 11.8 3.6 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NUDIX PF00293.28 AAAP01003598.1_2 - 1e-19 70.9 0.2 1.3e-19 70.5 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAAP01003598.1_2 - 2.9e-05 24.0 0.2 4.9e-05 23.3 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain DUF2385 PF09539.10 AAAP01003598.1_3 - 2e-29 102.0 0.0 2.2e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2385) Arg_decarbox_C PF17944.1 AAAP01003598.1_3 - 0.15 12.6 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension LysR_substrate PF03466.20 AAAP01003598.1_5 - 1.9e-38 131.9 13.6 3e-38 131.3 13.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003598.1_5 - 4.6e-16 58.5 0.5 4.6e-16 58.5 0.5 3.1 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AAAP01003598.1_5 - 0.03 13.5 0.1 0.57 9.3 0.0 2.6 3 0 0 3 3 3 0 PBP superfamily domain TauE PF01925.19 AAAP01003598.1_7 - 1.1e-18 67.8 31.2 1.2e-18 67.6 31.2 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Av_adeno_fibre PF06536.11 AAAP01003598.1_7 - 0.12 12.3 0.5 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal DnaB_C PF03796.15 AAAP01003599.1_2 - 5.2e-99 330.7 0.1 6.6e-99 330.4 0.1 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AAAP01003599.1_2 - 8e-25 86.9 0.0 2e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AAAP01003599.1_2 - 1.6e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003599.1_2 - 0.0011 19.4 0.1 0.012 16.0 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AAAP01003599.1_2 - 0.023 14.1 0.3 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 AAAP01003599.1_2 - 0.034 14.5 0.1 0.12 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Ala_racemase_C PF00842.21 AAAP01003599.1_3 - 1.7e-37 128.0 0.0 2.4e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Ala_racemase_N PF01168.20 AAAP01003599.1_3 - 4.2e-19 69.1 0.0 6.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ATPase PF06745.13 AAAP01003599.1_4 - 7e-19 68.1 0.2 5.9e-13 48.7 0.1 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 AAAP01003599.1_4 - 1.5e-18 67.1 1.0 6.9e-18 64.9 0.7 2.1 2 1 0 2 2 2 1 AAA domain Rubredoxin_2 PF18073.1 AAAP01003599.1_4 - 1.7e-10 40.4 6.8 2.5e-10 39.9 6.8 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain DnaB_C PF03796.15 AAAP01003599.1_4 - 2.3e-07 30.4 0.0 4.3e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain RecA PF00154.21 AAAP01003599.1_4 - 1e-05 25.1 0.3 1.4e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 AAAP01003599.1_4 - 2e-05 25.0 0.3 4.5e-05 23.9 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003599.1_4 - 0.00025 20.8 3.3 0.0012 18.6 3.3 1.9 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 AAAP01003599.1_4 - 0.00052 19.1 1.4 0.00081 18.4 0.2 1.8 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 AAAP01003599.1_4 - 0.00078 19.4 0.3 0.042 13.8 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.6 AAAP01003599.1_4 - 0.00085 19.1 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AAAP01003599.1_4 - 0.0026 17.8 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_26 PF13500.6 AAAP01003599.1_4 - 0.004 17.0 0.1 0.0073 16.2 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003599.1_4 - 0.0049 17.3 0.0 0.0092 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.11 AAAP01003599.1_4 - 0.0055 16.0 0.1 0.024 13.9 0.2 1.8 1 1 0 1 1 1 1 Rad51 IstB_IS21 PF01695.17 AAAP01003599.1_4 - 0.0058 16.4 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 AAAP01003599.1_4 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DAP3 PF10236.9 AAAP01003599.1_4 - 0.013 14.6 0.2 0.29 10.2 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 AAAP01003599.1_4 - 0.02 14.8 0.2 0.037 13.9 0.2 1.6 1 1 0 1 1 1 0 NACHT domain CbiA PF01656.23 AAAP01003599.1_4 - 0.022 14.8 0.0 0.12 12.4 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MCM PF00493.23 AAAP01003599.1_4 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 AAAP01003599.1_4 - 0.026 14.8 0.0 0.073 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ADK_lid PF05191.14 AAAP01003599.1_4 - 0.048 13.7 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_29 PF13555.6 AAAP01003599.1_4 - 0.083 12.6 0.4 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 AAAP01003599.1_4 - 0.095 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) VirC1 PF07015.11 AAAP01003599.1_4 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein ABC_tran PF00005.27 AAAP01003599.1_4 - 0.14 12.7 0.2 0.35 11.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter zf-RING_10 PF16685.5 AAAP01003599.1_4 - 0.22 11.7 0.5 0.35 11.1 0.5 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Pkinase PF00069.25 AAAP01003600.1_1 - 2.6e-08 33.5 0.0 3.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAAP01003600.1_1 - 7.6e-06 25.4 0.0 9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AAAP01003600.1_1 - 2.8e-05 24.1 0.1 4.4e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 AAAP01003600.1_1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 AAAP01003600.1_1 - 0.041 13.2 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like ketoacyl-synt PF00109.26 AAAP01003600.1_3 - 2.8e-59 200.8 0.3 7.5e-59 199.3 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AAAP01003600.1_3 - 8.7e-37 125.7 0.0 2.3e-36 124.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 AAAP01003600.1_3 - 2.9e-14 53.5 0.0 5.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Acyl_transf_1 PF00698.21 AAAP01003600.1_3 - 9.5e-06 25.3 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Coiled-coil_56 PF09813.9 AAAP01003600.1_3 - 0.21 11.6 0.0 0.7 10.0 0.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 GAF PF01590.26 AAAP01003601.1_1 - 7e-12 46.1 0.0 1.4e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AAAP01003601.1_1 - 8.5e-10 39.1 0.1 2.8e-08 34.2 0.0 2.9 3 0 0 3 3 3 1 GAF domain dCache_1 PF02743.18 AAAP01003601.1_1 - 1.3e-07 31.7 1.7 1.9e-07 31.1 0.0 2.2 3 0 0 3 3 3 1 Cache domain GAF_3 PF13492.6 AAAP01003601.1_1 - 4.8e-05 23.7 0.3 0.0054 17.1 0.0 3.6 2 1 1 3 3 3 1 GAF domain Orn_Arg_deC_N PF02784.16 AAAP01003602.1_1 - 6.7e-18 64.9 0.0 9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAAP01003602.1_1 - 4.9e-12 45.9 0.0 6.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAAP01003602.1_1 - 0.0052 16.5 0.2 0.0099 15.5 0.2 1.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain AAL_decarboxy PF03306.13 AAAP01003602.1_1 - 0.2 11.0 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase ParBc PF02195.18 AAAP01003602.1_2 - 4e-09 36.6 0.0 5.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain DUF1015 PF06245.11 AAAP01003602.1_2 - 0.0074 15.2 0.7 0.55 9.0 0.1 2.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1015) Tad PF13400.6 AAAP01003602.1_3 - 0.015 15.6 1.8 0.016 15.5 1.8 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Gram_pos_anchor PF00746.21 AAAP01003602.1_4 - 0.07 13.1 0.3 0.094 12.7 0.3 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Glt_symporter PF03616.14 AAAP01003602.1_4 - 0.17 10.5 0.3 0.17 10.6 0.3 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter MFS_1 PF07690.16 AAAP01003602.1_5 - 2e-39 135.5 47.0 2.4e-39 135.3 47.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.11 AAAP01003602.1_5 - 0.2 11.0 8.2 0.024 14.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) MFS_1_like PF12832.7 AAAP01003602.1_5 - 0.68 8.7 11.5 9.6 4.9 10.2 2.1 2 0 0 2 2 2 0 MFS_1 like family DUF892 PF05974.12 AAAP01003602.1_6 - 7e-64 214.6 5.5 7.9e-64 214.5 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) DUF4129 PF13559.6 AAAP01003602.1_6 - 0.0011 19.2 1.8 0.0016 18.6 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) DUF2383 PF09537.10 AAAP01003602.1_6 - 0.033 14.5 0.7 0.26 11.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) UPF0061 PF02696.14 AAAP01003602.1_7 - 2.6e-119 399.1 0.0 3.2e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DCD PF06559.11 AAAP01003603.1_2 - 3e-169 562.5 0.0 3.5e-169 562.3 0.0 1.0 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF525 PF04379.14 AAAP01003603.1_4 - 1.4e-35 121.4 0.0 1.7e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 ApaG domain LTD PF00932.19 AAAP01003603.1_4 - 0.071 13.5 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 Lamin Tail Domain DUF4354 PF14263.6 AAAP01003603.1_4 - 0.24 11.2 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) Bestrophin PF01062.21 AAAP01003603.1_6 - 4.2e-53 180.7 0.0 4.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel KAAG1 PF15354.6 AAAP01003603.1_6 - 0.27 11.8 3.2 0.49 11.0 3.2 1.4 1 0 0 1 1 1 0 Kidney-associated antigen 1 Form_Nir_trans PF01226.17 AAAP01003603.1_7 - 5.1e-41 140.6 14.0 6.3e-41 140.3 14.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter PHO4 PF01384.20 AAAP01003603.1_8 - 0.0093 15.1 0.1 0.0093 15.1 0.1 1.6 2 0 0 2 2 2 1 Phosphate transporter family HATPase_c PF02518.26 AAAP01003604.1_2 - 2.9e-19 69.6 0.0 2.3e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase cNMP_binding PF00027.29 AAAP01003604.1_2 - 2.1e-18 66.2 0.0 4.8e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HisKA PF00512.25 AAAP01003604.1_2 - 2e-11 43.8 2.7 5.6e-11 42.3 0.4 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003604.1_2 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 GHKL domain TPP_enzyme_C PF02775.21 AAAP01003604.1_3 - 2.3e-09 37.2 0.3 4.2e-09 36.4 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 AAAP01003604.1_3 - 3.4e-05 24.7 1.9 9.7e-05 23.2 1.7 1.9 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01003604.1_3 - 4.5e-05 24.0 2.6 6.1e-05 23.5 1.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003604.1_3 - 4.6e-05 23.5 1.2 4.6e-05 23.5 1.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003604.1_3 - 0.00083 19.1 4.6 0.00083 19.1 4.6 3.2 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003604.1_3 - 0.0012 18.9 1.1 0.0012 18.9 1.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003604.1_3 - 0.0017 18.5 3.3 0.0029 17.7 1.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003604.1_3 - 0.0067 16.5 3.5 0.0067 16.5 3.5 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003604.1_3 - 0.01 15.9 3.5 0.01 15.9 3.5 2.7 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003604.1_3 - 0.021 15.7 5.1 0.021 15.7 5.1 2.5 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003604.1_3 - 0.024 14.8 0.2 0.06 13.5 0.2 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003604.1_3 - 0.024 15.2 1.2 0.045 14.3 0.2 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003604.1_3 - 0.058 14.0 0.4 0.21 12.2 0.4 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 AAAP01003604.1_3 - 0.38 11.2 4.5 0.45 11.0 2.0 1.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003604.1_3 - 0.62 10.7 7.3 0.2 12.2 1.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 AAAP01003604.1_3 - 2.8 8.7 4.9 0.54 11.0 0.2 2.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain HTH_21 PF13276.6 AAAP01003605.1_2 - 1e-05 25.6 0.4 1.4e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 HTH-like domain HTH_Tnp_1 PF01527.20 AAAP01003605.1_3 - 5.6e-19 68.2 0.0 7.2e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01003605.1_3 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003605.1_3 - 0.018 15.1 0.0 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003605.1_3 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAAP01003605.1_3 - 0.054 13.6 0.1 0.07 13.3 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase Hemerythrin PF01814.23 AAAP01003605.1_4 - 2e-09 38.2 1.2 2.5e-09 37.8 1.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain WYL_2 PF10902.8 AAAP01003605.1_4 - 0.015 15.7 0.3 0.033 14.6 0.0 1.7 2 0 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold Hemerythrin PF01814.23 AAAP01003605.1_5 - 3.9e-08 34.0 0.1 8.1e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Response_reg PF00072.24 AAAP01003605.1_6 - 1.8e-05 24.8 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Hemerythrin PF01814.23 AAAP01003605.1_6 - 0.055 14.1 0.4 0.14 12.8 0.2 1.7 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain ACR_tran PF00873.19 AAAP01003606.1_1 - 3.7e-243 809.5 9.6 4.7e-243 809.2 9.6 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003606.1_1 - 6.9e-05 21.9 38.2 8.2e-05 21.7 15.2 2.7 2 1 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAAP01003606.1_1 - 0.54 9.6 22.5 1.7 8.0 7.4 3.1 2 1 0 2 2 2 0 Protein export membrane protein Rhodanese PF00581.20 AAAP01003607.1_1 - 1.4e-20 73.8 0.0 4.9e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain GGDEF PF00990.21 AAAP01003607.1_2 - 1.4e-52 177.6 0.0 2.4e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain sCache_2 PF17200.4 AAAP01003607.1_2 - 1e-34 119.7 0.0 1.7e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003607.1_2 - 9.3e-28 97.2 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Cache domain PAS_9 PF13426.7 AAAP01003607.1_2 - 8.6e-12 45.2 0.0 9.3e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003607.1_2 - 2.4e-11 43.6 0.0 4.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold Cache_3-Cache_2 PF17201.4 AAAP01003607.1_2 - 1.6e-09 37.5 0.0 2.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain PAS_4 PF08448.10 AAAP01003607.1_2 - 1.2e-06 28.7 0.0 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003607.1_2 - 3.5e-06 26.9 0.1 2.8e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain HAMP PF00672.25 AAAP01003607.1_2 - 5.9e-06 26.6 0.1 1.7e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 HAMP domain PAS_3 PF08447.12 AAAP01003607.1_2 - 0.00011 22.4 0.1 0.00062 20.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold Afaf PF15339.6 AAAP01003607.1_2 - 0.0053 16.5 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 Acrosome formation-associated factor PAS_7 PF12860.7 AAAP01003607.1_2 - 0.062 13.5 0.2 1.4 9.1 0.0 2.8 2 1 0 2 2 2 0 PAS fold SMBP PF16785.5 AAAP01003607.1_3 - 0.056 13.7 10.9 0.19 11.9 10.9 1.8 1 1 0 1 1 1 0 Small metal-binding protein PetM PF08041.11 AAAP01003607.1_3 - 0.078 12.6 2.8 0.15 11.7 2.8 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 BPD_transp_2 PF02653.16 AAAP01003608.1_2 - 1.3e-47 162.2 36.2 1.5e-47 162.0 36.2 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Diphtheria_T PF02764.14 AAAP01003608.1_2 - 0.083 12.9 0.6 0.25 11.3 0.7 1.7 2 0 0 2 2 2 0 Diphtheria toxin, T domain Peripla_BP_6 PF13458.6 AAAP01003608.1_3 - 6.4e-44 151.0 4.3 7.6e-44 150.8 4.3 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01003608.1_3 - 3.3e-17 62.6 0.0 4.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAAP01003608.1_3 - 3.2e-10 39.5 1.7 3.7e-07 29.5 0.1 2.0 2 0 0 2 2 2 2 Periplasmic binding protein domain VWA PF00092.28 AAAP01003608.1_3 - 0.11 12.7 0.7 0.73 10.1 0.2 2.2 1 1 1 2 2 2 0 von Willebrand factor type A domain AMP-binding PF00501.28 AAAP01003608.1_4 - 1.2e-35 122.9 0.1 2.5e-35 121.9 0.1 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003608.1_4 - 2.6e-15 57.1 1.0 4.1e-15 56.5 1.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OprB PF04966.12 AAAP01003609.1_1 - 9.5e-48 163.5 7.1 1.5e-47 162.8 7.1 1.3 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family OMP_b-brl PF13505.6 AAAP01003609.1_1 - 1.9e-10 41.2 3.9 1.9e-10 41.2 3.9 2.3 2 0 0 2 2 2 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 AAAP01003609.1_1 - 0.0024 17.6 0.1 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 OmpA-like transmembrane domain ParG PF09274.10 AAAP01003609.1_2 - 0.08 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 ParG CbiA PF01656.23 AAAP01003609.1_3 - 1e-18 67.6 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003609.1_3 - 6.2e-18 65.3 0.1 3.6e-12 46.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain ParA PF10609.9 AAAP01003609.1_3 - 4.4e-13 49.3 3.0 1.8e-08 34.2 0.4 2.2 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAAP01003609.1_3 - 4.6e-10 39.2 3.1 4.2e-06 26.2 0.0 2.9 1 1 2 3 3 3 2 ATPase MipZ VirC1 PF07015.11 AAAP01003609.1_3 - 4.2e-07 29.5 0.0 6.1e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 AAAP01003609.1_3 - 4.4e-06 26.3 0.0 0.0008 18.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 AAAP01003609.1_3 - 1.2e-05 24.5 0.4 7.9e-05 21.8 0.0 2.1 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 AAAP01003609.1_3 - 1.5e-05 24.3 0.0 3.2e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AAAP01003609.1_3 - 0.00015 21.3 0.1 0.0017 17.9 0.1 2.0 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 AAAP01003609.1_3 - 0.0005 19.9 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 AAAP01003609.1_3 - 0.0013 18.7 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 AAAP01003609.1_3 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 AAAP01003609.1_3 - 0.028 14.0 3.7 0.036 13.6 0.6 2.4 1 1 1 3 3 3 0 AAA domain B12-binding PF02310.19 AAAP01003609.1_3 - 0.033 14.2 1.1 11 6.1 0.3 2.7 1 1 2 3 3 3 0 B12 binding domain Methyltransf_24 PF13578.6 AAAP01003609.1_3 - 0.041 14.9 0.3 0.18 12.8 0.0 2.1 2 2 0 2 2 2 0 Methyltransferase domain DUF1611 PF07755.11 AAAP01003609.1_3 - 0.071 12.4 0.1 3.3 6.9 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain ATP_bind_1 PF03029.17 AAAP01003609.1_3 - 0.073 12.9 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 AAAP01003609.1_3 - 0.11 12.0 0.0 0.51 9.9 0.0 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B MarR_2 PF12802.7 AAAP01003609.1_4 - 0.00024 20.9 2.2 0.00024 20.9 2.2 3.1 3 1 1 4 4 4 1 MarR family GntR PF00392.21 AAAP01003609.1_4 - 0.00047 19.7 2.2 0.0019 17.8 2.2 2.1 1 1 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAAP01003609.1_4 - 0.0046 16.5 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Msg2_C PF12373.8 AAAP01003609.1_4 - 0.028 13.8 0.3 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal DUF977 PF06163.11 AAAP01003609.1_4 - 0.036 14.0 0.3 0.058 13.3 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_AsnC-type PF13404.6 AAAP01003609.1_4 - 0.039 13.8 1.8 0.081 12.8 0.2 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PP_kinase PF02503.17 AAAP01003610.1_1 - 9.3e-55 185.4 0.0 1.3e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C_1 PF17941.1 AAAP01003610.1_1 - 1.3e-47 161.4 0.1 2e-47 160.8 0.1 1.3 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_N PF13089.6 AAAP01003610.1_1 - 1.2e-36 125.3 0.0 2.3e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain MR_MLE_C PF13378.6 AAAP01003610.1_1 - 0.039 13.5 2.6 0.033 13.8 1.1 1.6 2 0 0 2 2 2 0 Enolase C-terminal domain-like His_Phos_1 PF00300.22 AAAP01003610.1_2 - 5.3e-10 39.3 0.1 1.3e-09 38.0 0.0 1.6 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) YAcAr PF10686.9 AAAP01003610.1_2 - 0.013 15.5 0.1 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family TPR_16 PF13432.6 AAAP01003610.1_3 - 5.9e-35 119.6 22.7 2.2e-08 34.6 0.6 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003610.1_3 - 1.6e-32 108.9 7.5 4.8e-06 26.3 0.3 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003610.1_3 - 1.1e-27 94.4 25.0 0.00012 22.6 0.0 7.6 2 1 6 8 8 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003610.1_3 - 2.8e-25 87.0 2.9 2.1e-05 24.1 0.4 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003610.1_3 - 8.6e-24 83.8 14.1 3.3e-07 30.7 0.8 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003610.1_3 - 6e-23 79.5 7.5 3.6e-05 23.9 0.1 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003610.1_3 - 2.8e-22 78.1 4.9 0.00043 19.9 0.0 6.3 3 2 3 6 6 6 5 TPR repeat TPR_6 PF13174.6 AAAP01003610.1_3 - 3.4e-19 68.1 5.1 0.00052 20.5 0.0 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003610.1_3 - 4e-17 60.9 4.6 0.032 14.3 0.1 7.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003610.1_3 - 6.4e-17 60.3 0.4 0.017 15.3 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003610.1_3 - 2e-15 56.8 18.0 8.5e-05 22.8 1.2 6.5 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003610.1_3 - 1.6e-12 46.8 25.3 0.013 15.4 0.1 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003610.1_3 - 7e-12 45.3 16.8 3.6e-06 27.0 0.6 4.8 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003610.1_3 - 1.2e-07 31.7 30.8 2.8 8.8 0.4 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003610.1_3 - 4.3e-07 30.1 0.1 0.093 13.0 0.0 3.5 1 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 AAAP01003610.1_3 - 6.7e-07 29.5 10.1 0.62 10.4 0.2 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003610.1_3 - 1.7e-06 27.5 4.6 0.0017 17.6 0.1 3.4 1 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 AAAP01003610.1_3 - 2e-06 28.3 14.2 0.018 15.5 0.8 4.4 2 1 3 5 5 4 3 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 AAAP01003610.1_3 - 2.5e-05 23.9 3.6 0.56 9.8 0.0 4.2 1 1 4 5 5 5 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 AAAP01003610.1_3 - 0.00028 20.7 1.2 0.00075 19.3 0.3 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 AAAP01003610.1_3 - 0.00042 19.8 0.0 0.69 9.3 0.0 2.4 2 1 0 2 2 2 2 Coatomer epsilon subunit NARP1 PF12569.8 AAAP01003610.1_3 - 0.0017 17.3 0.1 1.4 7.8 0.0 2.8 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 YfiO PF13525.6 AAAP01003610.1_3 - 0.013 15.2 0.0 0.085 12.6 0.0 2.3 2 1 0 2 2 2 0 Outer membrane lipoprotein Fis1_TPR_C PF14853.6 AAAP01003610.1_3 - 0.022 14.8 0.2 23 5.2 0.0 3.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TAF1_subA PF14929.6 AAAP01003610.1_3 - 0.043 13.2 0.0 8.1 5.8 0.0 2.6 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A TPR_18 PF13512.6 AAAP01003610.1_3 - 0.093 12.9 0.0 1.8 8.7 0.0 2.8 3 1 1 4 4 3 0 Tetratricopeptide repeat HemY_N PF07219.13 AAAP01003610.1_3 - 3.2 8.0 10.8 7.9 6.7 0.0 4.1 3 2 2 5 5 4 0 HemY protein N-terminus PAS_9 PF13426.7 AAAP01003611.1_1 - 1.4e-40 137.7 0.0 5.7e-18 65.1 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AAAP01003611.1_1 - 1.8e-34 118.1 0.0 1.3e-14 54.2 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AAAP01003611.1_1 - 2.1e-28 98.8 0.1 1.1e-11 45.0 0.0 3.8 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 AAAP01003611.1_1 - 1.8e-20 73.0 0.9 5.4e-09 36.2 0.1 3.5 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AAAP01003611.1_1 - 4.1e-19 68.1 0.0 4.9e-05 23.2 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_12 PF18095.1 AAAP01003611.1_1 - 0.0004 20.0 0.0 0.15 11.7 0.0 2.6 3 0 0 3 3 3 2 UPF0242 C-terminal PAS-like domain Potyvirid-P3 PF13608.6 AAAP01003611.1_1 - 0.067 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein CFIA_Pcf11 PF11526.8 AAAP01003611.1_1 - 0.19 12.3 0.2 0.49 10.9 0.2 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 His_Phos_1 PF00300.22 AAAP01003611.1_2 - 1.8e-06 27.8 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Response_reg PF00072.24 AAAP01003611.1_3 - 1.3e-25 89.8 0.5 3.2e-25 88.5 0.0 1.9 3 0 0 3 3 3 1 Response regulator receiver domain HD_5 PF13487.6 AAAP01003611.1_3 - 3.4e-17 62.4 0.0 1.5e-16 60.4 0.0 2.0 1 1 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003611.1_3 - 1.9e-13 50.7 0.0 1.6e-12 47.7 0.0 2.5 2 1 0 2 2 2 1 HD domain GGDEF PF00990.21 AAAP01003612.1_1 - 2.9e-42 144.2 0.0 4.2e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain EAL PF00563.20 AAAP01003612.1_1 - 4.4e-22 78.8 0.0 7.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 EAL domain PAS_8 PF13188.7 AAAP01003612.1_1 - 0.00024 21.0 0.1 0.0032 17.5 0.0 2.6 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003612.1_1 - 0.0021 18.0 0.0 0.037 14.0 0.0 2.6 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAAP01003612.1_1 - 0.029 14.6 0.0 1.3 9.3 0.0 3.1 3 1 1 4 4 4 0 PAS fold NUDIX PF00293.28 AAAP01003612.1_2 - 3.9e-19 69.0 0.1 6.6e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 AAAP01003612.1_2 - 2.3e-16 60.3 0.3 7.7e-16 58.6 0.3 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 AAAP01003612.1_2 - 2.2e-07 30.4 1.8 3.6e-07 29.7 1.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PRK PF00485.18 AAAP01003612.1_3 - 1.4e-71 240.3 0.0 1.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 AAAP01003612.1_3 - 0.0029 16.6 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 AAAP01003612.1_3 - 0.0046 16.9 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 AAAP01003612.1_3 - 0.048 12.9 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin RuBisCO_large PF00016.20 AAAP01003612.1_4 - 4.1e-84 282.3 0.5 4.9e-84 282.1 0.5 1.0 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain Phage_int_SAM_3 PF14659.6 AAAP01003613.1_1 - 0.0021 18.3 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAAP01003613.1_1 - 0.022 15.2 0.2 0.41 11.1 0.1 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AAAP01003613.1_1 - 0.062 13.6 0.0 0.21 12.0 0.0 1.9 2 1 0 2 2 2 0 Phage integrase SAM-like domain HIRAN PF08797.11 AAAP01003613.1_2 - 4.2e-08 33.0 0.0 6.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 HIRAN domain DUF3987 PF13148.6 AAAP01003613.1_3 - 1.9e-18 66.7 2.4 3.5e-18 65.8 2.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3987) DDE_Tnp_IS1 PF03400.13 AAAP01003613.1_3 - 0.16 12.3 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 IS1 transposase MCPsignal PF00015.21 AAAP01003614.1_1 - 2.8e-33 115.2 38.5 2.3e-31 108.9 24.5 2.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 AAAP01003614.1_1 - 0.00032 21.0 8.8 0.17 12.3 0.2 3.9 3 1 1 4 4 4 2 Syntaxin-like protein DUF948 PF06103.11 AAAP01003614.1_1 - 0.00052 20.2 15.3 0.46 10.8 2.1 4.1 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 AAAP01003614.1_1 - 0.0037 16.6 2.8 0.0037 16.6 2.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3450) DUF3726 PF12525.8 AAAP01003614.1_1 - 0.0057 16.7 3.9 0.027 14.6 0.1 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF3726) DUF1664 PF07889.12 AAAP01003614.1_1 - 0.02 14.9 10.8 0.39 10.8 1.9 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 AAAP01003614.1_1 - 0.036 14.1 18.3 0.049 13.6 0.7 3.7 1 1 4 5 5 5 0 Laminin Domain II Laminin_I PF06008.14 AAAP01003614.1_1 - 0.064 13.0 26.0 0.096 12.4 2.3 3.8 1 1 1 3 3 3 0 Laminin Domain I BAR PF03114.18 AAAP01003614.1_1 - 0.27 10.8 7.3 0.054 13.1 0.4 3.0 2 2 0 2 2 2 0 BAR domain Mur_ligase_C PF02875.21 AAAP01003614.1_1 - 0.58 10.4 2.9 8.4 6.7 0.1 2.8 1 1 1 3 3 3 0 Mur ligase family, glutamate ligase domain ISG65-75 PF11727.8 AAAP01003614.1_1 - 0.76 9.0 19.6 0.46 9.7 3.7 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein FlaC_arch PF05377.11 AAAP01003614.1_1 - 1.7 9.1 10.3 1.8 9.1 0.1 4.8 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Lin-8 PF03353.15 AAAP01003614.1_1 - 6.7 6.2 9.7 2.7 7.5 4.7 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TetR_C_16 PF17920.1 AAAP01003614.1_3 - 0.16 12.3 5.2 0.13 12.5 3.2 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SLT PF01464.20 AAAP01003614.1_4 - 7.4e-14 51.4 0.0 1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF202 PF02656.15 AAAP01003614.1_5 - 1.9 9.0 10.0 2.3 8.7 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Abhydrolase_3 PF07859.13 AAAP01003615.1_1 - 6.1e-51 173.3 0.0 7.5e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 AAAP01003615.1_1 - 0.0001 21.3 0.0 0.00027 19.9 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 AAAP01003615.1_1 - 0.00027 20.3 0.1 0.0012 18.1 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peripla_BP_6 PF13458.6 AAAP01003615.1_1 - 0.0089 15.7 0.3 0.27 10.8 0.1 2.6 3 0 0 3 3 3 1 Periplasmic binding protein DLH PF01738.18 AAAP01003615.1_1 - 0.052 13.1 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAAP01003615.1_1 - 0.19 11.2 0.0 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pyr_redox_3 PF13738.6 AAAP01003615.1_2 - 4e-18 65.7 0.0 5.1e-16 58.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AAAP01003615.1_2 - 1.6e-14 53.2 0.0 2.8e-13 49.2 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 AAAP01003615.1_2 - 1.5e-10 41.1 2.7 1e-09 38.5 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01003615.1_2 - 2.4e-09 36.8 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAAP01003615.1_2 - 2.7e-06 26.8 0.0 0.0066 15.6 0.0 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AAAP01003615.1_2 - 2.5e-05 23.5 0.2 5.2e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 AAAP01003615.1_2 - 0.00037 20.2 0.7 0.0019 17.8 0.3 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 AAAP01003615.1_2 - 0.018 14.1 0.0 0.81 8.7 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01003615.1_2 - 0.022 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 AAAP01003615.1_2 - 0.068 13.7 0.1 3.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01003615.1_2 - 0.081 12.9 0.6 0.35 10.9 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 AAAP01003615.1_2 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 AAAP01003615.1_2 - 0.17 10.6 0.1 0.54 8.9 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF4856 PF16148.5 AAAP01003615.1_2 - 0.32 9.9 0.0 0.47 9.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4856) DUF2721 PF11026.8 AAAP01003615.1_3 - 1.1e-25 90.0 12.1 1.2e-25 89.8 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) US6 PF17616.2 AAAP01003615.1_3 - 0.026 14.5 0.9 0.034 14.1 0.9 1.2 1 0 0 1 1 1 0 Viral unique short region 6 DUF2207 PF09972.9 AAAP01003615.1_3 - 0.43 9.3 0.6 0.5 9.1 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CcmD PF04995.14 AAAP01003615.1_3 - 5 7.3 14.3 0.2 11.7 0.6 3.6 3 1 0 3 3 3 0 Heme exporter protein D (CcmD) LAB_N PF07578.11 AAAP01003615.1_4 - 1.7e-29 101.7 2.3 2.8e-29 101.0 2.3 1.3 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain MtN3_slv PF03083.16 AAAP01003615.1_4 - 0.069 13.2 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Glycos_transf_2 PF00535.26 AAAP01003615.1_5 - 8.9e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 HATPase_c PF02518.26 AAAP01003616.1_2 - 4.3e-24 85.2 0.0 1.4e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAAP01003616.1_2 - 5e-20 71.7 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain dCache_1 PF02743.18 AAAP01003616.1_2 - 1.3e-18 67.7 0.0 2.1e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Cache domain PAS PF00989.25 AAAP01003616.1_2 - 6.4e-16 58.4 0.0 1.4e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003616.1_2 - 3.7e-12 46.5 0.0 2.8e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AAAP01003616.1_2 - 3.8e-12 46.1 0.6 1e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01003616.1_2 - 3.4e-11 43.3 0.0 1.2e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003616.1_2 - 0.00023 21.1 0.0 0.00082 19.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AAAP01003616.1_2 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 GHKL domain DUF4381 PF14316.6 AAAP01003616.1_2 - 0.04 14.1 2.0 1 9.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Glyco_hydro_4C PF11975.8 AAAP01003616.1_3 - 3.9e-25 89.2 0.1 4.2e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain TPD PF14811.6 AAAP01003616.1_3 - 0.17 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif PALP PF00291.25 AAAP01003617.1_1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Peptidase_M16 PF00675.20 AAAP01003617.1_2 - 7.3e-38 129.9 0.0 1.4e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAAP01003617.1_2 - 9.8e-37 126.7 0.0 1.4e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2613 PF11021.8 AAAP01003617.1_3 - 2 8.6 5.4 0.83 9.8 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) GFO_IDH_MocA PF01408.22 AAAP01003617.1_4 - 9.6e-27 94.2 0.1 1.5e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAAP01003617.1_4 - 6.6e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PAP2 PF01569.21 AAAP01003617.1_5 - 5.6e-26 90.9 6.9 5.6e-26 90.9 6.9 1.8 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AAAP01003617.1_5 - 3.3e-07 30.2 13.7 1.9e-06 27.7 13.7 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF1392 PF07154.11 AAAP01003617.1_5 - 0.17 12.0 0.3 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1392) PAP2_C PF14360.6 AAAP01003617.1_5 - 0.26 11.9 3.9 0.31 11.6 0.6 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF1772 PF08592.11 AAAP01003617.1_5 - 3.3 8.0 17.4 0.74 10.1 1.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) 2_5_RNA_ligase2 PF13563.6 AAAP01003617.1_6 - 1.8e-10 40.9 0.4 2e-10 40.8 0.4 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAS_4 PF08448.10 AAAP01003618.1_1 - 9.8e-09 35.5 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003618.1_1 - 0.0044 17.0 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003618.1_1 - 0.072 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 PAS domain SAMP PF05924.11 AAAP01003618.1_2 - 0.0078 15.5 0.2 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 SAMP Motif RuvA_C PF07499.13 AAAP01003618.1_2 - 0.039 14.4 0.1 0.064 13.7 0.1 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain PRKCSH_1 PF13015.6 AAAP01003618.1_2 - 0.11 12.1 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Phage_integrase PF00589.22 AAAP01003618.1_3 - 4.6e-10 39.5 0.1 1.8e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Phage integrase family DUF3216 PF11505.8 AAAP01003618.1_3 - 0.067 13.4 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) GMP_synt_C PF00958.22 AAAP01003618.1_4 - 4.3e-38 129.2 0.0 4.8e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 GMP synthase C terminal domain Anticodon_1 PF08264.13 AAAP01003619.1_2 - 3.7e-38 130.9 0.0 6.2e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AAAP01003619.1_2 - 4.3e-18 65.4 3.7 9.4e-18 64.3 3.7 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1 PF00133.22 AAAP01003619.1_2 - 1.7e-09 36.5 0.0 4.5e-09 35.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01003619.1_2 - 0.00015 20.6 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) ABC_tran_CTD PF16326.5 AAAP01003619.1_2 - 0.00088 19.5 0.8 0.0022 18.2 0.8 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF2789 PF10982.8 AAAP01003619.1_2 - 0.043 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) DUF1192 PF06698.11 AAAP01003619.1_2 - 0.18 11.9 1.6 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) GGDEF PF00990.21 AAAP01003619.1_3 - 4.1e-34 117.6 0.2 7.3e-34 116.8 0.2 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003619.1_3 - 8.5e-32 109.5 0.0 1.5e-14 54.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003619.1_3 - 7.7e-23 80.7 0.0 3.3e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01003619.1_3 - 6.8e-15 55.3 1.4 3.3e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 AAAP01003619.1_3 - 6.6e-14 52.0 0.1 7.4e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01003619.1_3 - 3.2e-12 46.2 0.0 2e-06 27.7 0.0 3.2 3 0 0 3 3 3 2 PAS domain PilJ PF13675.6 AAAP01003619.1_3 - 2.7e-06 27.4 0.0 6.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term PAS_7 PF12860.7 AAAP01003619.1_3 - 1.5e-05 25.1 0.3 0.23 11.6 0.0 4.3 5 0 0 5 5 5 2 PAS fold PAS_12 PF18095.1 AAAP01003619.1_3 - 3.9e-05 23.3 0.0 0.35 10.5 0.0 2.4 2 0 0 2 2 2 2 UPF0242 C-terminal PAS-like domain rve PF00665.26 AAAP01003620.1_1 - 2.9e-26 92.0 0.0 3.7e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01003620.1_1 - 5e-22 77.5 0.2 8e-22 76.8 0.2 1.3 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01003620.1_1 - 0.00035 20.7 0.0 0.0015 18.7 0.0 1.9 1 1 1 2 2 2 1 Integrase core domain SnoaL PF07366.12 AAAP01003620.1_2 - 0.19 11.5 0.2 0.57 10.0 0.1 1.8 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase HisKA PF00512.25 AAAP01003620.1_3 - 0.00013 21.9 0.1 0.00041 20.3 0.1 1.9 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TetR_C_20 PF17925.1 AAAP01003620.1_3 - 0.026 14.8 1.0 0.044 14.1 0.1 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HATPase_c PF02518.26 AAAP01003620.1_3 - 0.026 15.0 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0542 PF15086.6 AAAP01003620.1_3 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 UcrQ PF02939.16 AAAP01003620.1_3 - 0.13 12.2 0.1 0.36 10.8 0.1 1.7 2 0 0 2 2 2 0 UcrQ family End3 PF12761.7 AAAP01003620.1_3 - 0.16 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Phage_holin_3_6 PF07332.11 AAAP01003620.1_3 - 3 7.9 5.7 12 6.0 1.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III sCache_2 PF17200.4 AAAP01003621.1_1 - 5e-35 120.6 0.6 7.4e-35 120.1 0.0 1.5 2 0 0 2 2 2 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003621.1_1 - 1.3e-29 103.3 0.0 5.4e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Cache domain HAMP PF00672.25 AAAP01003621.1_1 - 1.7e-06 28.3 0.9 6.8e-06 26.4 0.2 2.4 3 0 0 3 3 3 1 HAMP domain Cache_3-Cache_2 PF17201.4 AAAP01003621.1_1 - 3.2e-06 26.7 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain NOG1_N PF17835.1 AAAP01003621.1_1 - 0.15 12.0 0.5 7.5 6.5 0.0 2.2 2 0 0 2 2 2 0 NOG1 N-terminal helical domain Hemerythrin PF01814.23 AAAP01003621.1_2 - 4.3e-07 30.6 1.7 5.6e-07 30.2 1.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GST_N PF02798.20 AAAP01003621.1_3 - 1.7e-15 57.1 0.0 3.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003621.1_3 - 4.4e-11 42.9 0.0 1e-10 41.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AAAP01003621.1_3 - 8e-11 42.2 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAAP01003621.1_3 - 1.9e-09 37.6 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAAP01003621.1_3 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AAAP01003621.1_3 - 7e-06 26.0 0.1 1.5e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain sCache_2 PF17200.4 AAAP01003621.1_4 - 6.7e-40 136.5 0.0 1.8e-39 135.1 0.0 1.8 1 0 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003621.1_4 - 1.5e-34 119.5 0.0 5.1e-34 117.8 0.0 1.7 2 0 0 2 2 2 1 Cache domain MCPsignal PF00015.21 AAAP01003621.1_4 - 9.8e-23 80.8 22.3 1.3e-21 77.2 7.0 2.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Cache_3-Cache_2 PF17201.4 AAAP01003621.1_4 - 2.5e-12 46.7 1.6 1.7e-11 43.9 0.0 2.4 2 1 0 2 2 2 1 Cache 3/Cache 2 fusion domain HAMP PF00672.25 AAAP01003621.1_4 - 5.1e-09 36.4 3.6 1.1e-08 35.3 0.2 3.0 3 0 0 3 3 3 1 HAMP domain Adeno_PV PF03910.13 AAAP01003621.1_4 - 0.14 10.8 2.7 0.2 10.3 2.7 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV BLOC1_2 PF10046.9 AAAP01003621.1_4 - 0.16 12.3 1.4 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SQHop_cyclase_C PF13243.6 AAAP01003622.1_1 - 2.8e-90 302.7 1.0 3.1e-90 302.5 1.0 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 AAAP01003622.1_1 - 2e-21 75.4 8.9 1.4e-11 44.0 1.2 3.6 3 1 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 AAAP01003622.1_1 - 8.5e-11 41.5 0.8 6.4e-06 25.5 0.3 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 AAAP01003622.1_1 - 0.00068 18.8 0.1 0.025 13.6 0.0 2.4 1 1 1 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 AAAP01003622.1_1 - 0.0074 15.6 1.0 8.2 5.6 0.0 3.4 3 1 0 3 3 3 1 Pectic acid lyase PNP_UDP_1 PF01048.20 AAAP01003622.1_2 - 1.4e-16 60.4 3.4 6.1e-15 55.1 1.9 2.7 1 1 1 2 2 2 1 Phosphorylase superfamily DUF3463 PF11946.8 AAAP01003622.1_3 - 6.2e-61 204.1 0.2 1.1e-60 203.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) Radical_SAM PF04055.21 AAAP01003622.1_3 - 2.9e-14 53.8 0.0 5.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01003622.1_3 - 0.00053 20.3 0.0 0.0065 16.7 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003622.1_3 - 0.0012 19.0 0.6 0.0035 17.4 0.6 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain HMGL-like PF00682.19 AAAP01003622.1_3 - 0.1 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 HMGL-like Trans_reg_C PF00486.28 AAAP01003622.1_4 - 4.3e-28 97.2 0.0 6.4e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 AAAP01003622.1_4 - 0.23 11.1 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Glyco_transf_41 PF13844.6 AAAP01003623.1_1 - 1.9e-53 181.6 0.0 3.9e-46 157.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 DHO_dh PF01180.21 AAAP01003623.1_3 - 7.9e-11 41.7 0.0 2.4e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AAAP01003623.1_3 - 0.00058 19.4 0.3 0.12 11.8 0.1 3.0 1 1 2 3 3 3 2 Histidine biosynthesis protein FMN_dh PF01070.18 AAAP01003623.1_3 - 0.033 13.2 0.8 0.089 11.8 0.7 1.8 1 1 0 1 1 1 0 FMN-dependent dehydrogenase IMPDH PF00478.25 AAAP01003623.1_3 - 0.048 12.6 0.2 0.18 10.8 0.2 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain AP_endonuc_2 PF01261.24 AAAP01003623.1_3 - 0.069 12.6 0.0 0.32 10.4 0.0 2.0 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Yae1_N PF09811.9 AAAP01003624.1_1 - 0.02 14.6 1.0 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal RMF PF04957.12 AAAP01003624.1_1 - 0.16 12.2 1.3 15 5.9 0.0 2.2 2 0 0 2 2 2 0 Ribosome modulation factor Ribonuc_L-PSP PF01042.21 AAAP01003624.1_2 - 9.2e-18 64.4 0.0 1.1e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ApbA_C PF08546.11 AAAP01003624.1_2 - 0.1 12.8 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Rubrerythrin PF02915.17 AAAP01003624.1_3 - 4.4e-05 23.9 0.6 0.00037 20.9 0.6 1.9 1 1 0 1 1 1 1 Rubrerythrin TPP_enzyme_C PF02775.21 AAAP01003624.1_4 - 1.2e-28 99.8 0.1 1.9e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 AAAP01003624.1_4 - 0.036 14.2 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 AAAP01003624.1_5 - 9e-52 176.1 0.1 1.4e-51 175.5 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AAAP01003624.1_5 - 2.6e-10 40.7 0.0 4.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AAAP01003624.1_5 - 2.7e-08 34.0 0.0 5.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AAAP01003624.1_5 - 3e-08 33.6 0.0 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_N PF02776.18 AAAP01003624.1_5 - 0.012 15.2 0.3 0.028 14.0 0.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain mit_SMPDase PF14724.6 AAAP01003624.1_5 - 0.29 9.0 0.0 0.43 8.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF3850 PF12961.7 AAAP01003625.1_1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Adenine_glyco PF03352.13 AAAP01003625.1_2 - 3.7e-40 137.6 0.0 1.7e-38 132.2 0.0 2.0 1 1 1 2 2 2 2 Methyladenine glycosylase Glyoxalase_4 PF13669.6 AAAP01003625.1_3 - 4.7e-21 75.1 0.0 5.6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 AAAP01003625.1_3 - 2.2e-11 44.1 0.0 2.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 AAAP01003625.1_3 - 8.4e-07 29.3 0.0 1e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AAAP01003625.1_3 - 7.3e-05 23.5 0.0 9.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Penicil_amidase PF01804.18 AAAP01003625.1_4 - 2.2e-141 473.1 2.4 2.5e-141 472.9 2.4 1.0 1 0 0 1 1 1 1 Penicillin amidase Mpt_N PF09176.11 AAAP01003626.1_1 - 1.4e-19 70.0 0.8 4e-19 68.5 0.1 2.1 2 0 0 2 2 2 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal THF_DHG_CYH_C PF02882.19 AAAP01003626.1_1 - 0.00022 20.6 0.1 0.00033 20.0 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 AAAP01003626.1_1 - 0.0004 19.9 0.9 0.00064 19.2 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 AAAP01003626.1_1 - 0.0011 19.1 0.4 0.0011 19.1 0.4 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AAAP01003626.1_1 - 0.0025 17.7 0.5 0.0025 17.7 0.5 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAAP01003626.1_1 - 0.0033 18.0 3.3 0.0049 17.4 0.7 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 AAAP01003626.1_1 - 0.0037 16.6 0.1 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 AAAP01003626.1_1 - 0.0041 17.5 0.6 0.0041 17.5 0.6 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AAAP01003626.1_1 - 0.0087 16.3 0.4 0.017 15.4 0.4 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AAAP01003626.1_1 - 0.023 14.0 0.5 0.077 12.3 0.5 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 AAAP01003626.1_1 - 0.03 13.9 0.4 0.052 13.1 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family YjeF_N PF03853.15 AAAP01003626.1_1 - 0.033 14.1 4.0 0.028 14.3 2.2 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus ApbA PF02558.16 AAAP01003626.1_1 - 0.042 13.5 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 AAAP01003626.1_1 - 0.071 13.2 1.3 0.11 12.5 1.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Staph_opine_DH PF10100.9 AAAP01003626.1_1 - 0.18 10.4 0.2 0.24 10.0 0.2 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase FTCD_C PF04961.12 AAAP01003626.1_2 - 1.9e-69 233.1 4.0 2.2e-69 232.9 4.0 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase CRISPR_Cse1 PF09481.10 AAAP01003626.1_2 - 0.0021 17.2 0.2 0.0025 17.0 0.2 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) Glyco_hydro_80 PF13647.6 AAAP01003626.1_2 - 0.023 14.2 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 80 of chitosanase A Ligase_CoA PF00549.19 AAAP01003626.1_4 - 0.00036 20.4 0.1 0.0004 20.2 0.1 1.0 1 0 0 1 1 1 1 CoA-ligase Ligase_CoA PF00549.19 AAAP01003626.1_5 - 8e-14 51.7 0.1 1.5e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 AAAP01003626.1_5 - 3.8e-11 43.5 0.7 2.8e-10 40.7 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 AAAP01003626.1_5 - 5.7e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain PEPcase PF00311.17 AAAP01003626.1_6 - 1.3e-117 394.0 0.0 1.7e-117 393.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase HATPase_c_5 PF14501.6 AAAP01003627.1_1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 GHKL domain HATPase_c PF02518.26 AAAP01003627.1_2 - 1.5e-07 31.9 0.0 1.6e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01003627.1_5 - 2.3e-21 76.4 0.0 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003627.1_5 - 4.8e-09 36.5 2.6 1.1e-07 32.1 0.4 3.0 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 AAAP01003627.1_5 - 2.2e-06 27.5 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003627.1_5 - 0.0019 18.2 0.3 0.0089 16.0 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAAP01003627.1_5 - 0.12 12.3 0.0 0.46 10.4 0.0 1.8 1 1 0 1 1 1 0 GHKL domain HisKA PF00512.25 AAAP01003627.1_5 - 0.13 12.3 1.6 0.21 11.6 0.2 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAAP01003627.1_6 - 3.5e-22 78.7 0.0 4.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003627.1_6 - 8.6e-20 70.6 0.4 1.7e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FCD PF07729.12 AAAP01003627.1_7 - 1.1e-24 87.2 12.1 2.1e-24 86.4 12.1 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01003627.1_7 - 3.9e-19 68.1 1.8 5.5e-19 67.6 0.3 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAAP01003627.1_7 - 6.4e-05 22.9 0.1 0.00017 21.5 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 AAAP01003627.1_7 - 0.0016 18.0 0.1 0.0049 16.4 0.0 1.8 2 0 0 2 2 2 1 CodY helix-turn-helix domain HTH_24 PF13412.6 AAAP01003627.1_7 - 0.0088 15.6 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AAAP01003627.1_7 - 0.014 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AAAP01003627.1_7 - 0.031 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 AAAP01003627.1_7 - 0.037 14.1 1.4 0.15 12.2 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_TAC_6 PF09550.10 AAAP01003627.1_7 - 0.39 11.2 0.1 0.39 11.2 0.1 2.3 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC MadM PF03818.13 AAAP01003627.1_8 - 3.3e-24 84.5 5.0 3.3e-24 84.5 5.0 2.8 2 0 0 2 2 2 1 Malonate/sodium symporter MadM subunit BCAS3 PF12490.8 AAAP01003627.1_8 - 0.3 10.6 0.1 0.44 10.0 0.1 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF2929 PF11151.8 AAAP01003627.1_8 - 4.8 7.6 8.7 5.2 7.4 0.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2929) MadL PF03817.13 AAAP01003627.1_9 - 1.1e-45 154.5 15.4 1.3e-45 154.2 15.4 1.1 1 0 0 1 1 1 1 Malonate transporter MadL subunit LrgA PF03788.14 AAAP01003627.1_9 - 0.3 11.0 11.0 0.086 12.8 8.1 1.5 1 1 1 2 2 2 0 LrgA family SNARE_assoc PF09335.11 AAAP01003627.1_9 - 0.34 11.4 6.9 0.53 10.8 0.2 2.3 2 0 0 2 2 2 0 SNARE associated Golgi protein Mal_decarbox_Al PF16957.5 AAAP01003627.1_10 - 3.7e-107 358.9 0.0 4.6e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter CoA_trans PF01144.23 AAAP01003627.1_10 - 0.064 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Coenzyme A transferase GCV_T PF01571.21 AAAP01003628.1_1 - 3.3e-66 223.3 0.1 5.5e-66 222.6 0.0 1.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain SO_alpha_A3 PF17806.1 AAAP01003628.1_1 - 1.3e-31 108.7 0.0 3e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain SoxG PF04268.12 AAAP01003628.1_1 - 0.006 16.8 0.0 0.25 11.5 0.0 2.3 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Esterase_phd PF10503.9 AAAP01003628.1_1 - 0.033 13.7 0.3 0.033 13.7 0.3 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase SoxD PF04267.12 AAAP01003628.1_3 - 7.9e-33 112.4 0.1 9.1e-33 112.2 0.1 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, delta subunit family PIN_10 PF18478.1 AAAP01003628.1_3 - 0.049 13.9 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 PIN like domain DAO PF01266.24 AAAP01003628.1_4 - 4e-59 201.0 3.5 4.7e-59 200.7 3.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAAP01003628.1_4 - 1.1e-06 27.8 3.0 0.00016 20.6 0.6 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 AAAP01003628.1_4 - 3.2e-06 26.6 0.5 1.4e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 AAAP01003628.1_4 - 4.9e-06 26.7 0.5 2.2e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01003628.1_4 - 5e-06 25.9 3.4 0.00045 19.4 1.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 AAAP01003628.1_4 - 5.3e-06 25.9 0.6 0.0088 15.3 0.7 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003628.1_4 - 0.00047 19.5 0.3 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003628.1_4 - 0.0076 15.0 0.9 1.5 7.5 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 AAAP01003628.1_4 - 0.008 15.5 0.8 0.015 14.6 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 AAAP01003628.1_4 - 0.012 15.6 0.4 0.041 13.9 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 AAAP01003628.1_4 - 0.04 13.2 0.2 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GARS_N PF02844.15 AAAP01003628.1_4 - 0.056 14.2 0.1 2.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Pyr_redox PF00070.27 AAAP01003628.1_4 - 0.069 13.7 1.7 4.6 7.9 1.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAAP01003628.1_4 - 0.14 11.5 1.0 4.9 6.4 0.9 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase MCRA PF06100.11 AAAP01003628.1_4 - 0.21 10.4 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 MCRA family HTH_18 PF12833.7 AAAP01003628.1_5 - 7e-12 45.4 5.3 7e-12 45.4 5.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 AAAP01003628.1_5 - 3.1e-11 43.3 0.0 4.2e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_31 PF13560.6 AAAP01003628.1_5 - 0.0055 17.0 12.1 0.45 10.9 2.5 2.8 1 1 1 2 2 2 2 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01003628.1_5 - 0.47 10.5 5.8 1.2 9.1 1.0 2.5 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Glycos_transf_2 PF00535.26 AAAP01003629.1_2 - 2.1e-24 86.2 0.0 2.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003629.1_2 - 4.5e-11 43.1 0.0 4.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003629.1_2 - 0.0012 19.3 0.0 0.003 18.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 NTP_transf_3 PF12804.7 AAAP01003629.1_2 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_2 PF10111.9 AAAP01003629.1_2 - 0.0064 16.0 0.0 0.0088 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Epimerase PF01370.21 AAAP01003629.1_3 - 1.5e-37 129.4 0.0 1.3e-35 123.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003629.1_3 - 3.1e-30 105.7 0.0 1.8e-28 100.0 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01003629.1_3 - 9.5e-12 44.6 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAAP01003629.1_3 - 2.3e-08 33.5 0.0 3.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AAAP01003629.1_3 - 0.0017 17.5 0.0 0.0094 15.1 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAAP01003629.1_3 - 0.0024 16.9 0.0 0.0041 16.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 AAAP01003629.1_3 - 0.021 14.4 0.0 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003629.1_3 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 AAAP01003629.1_3 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 AAAP01003629.1_4 - 3e-13 49.9 0.0 5.5e-13 49.0 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003629.1_4 - 4.8e-13 49.1 0.0 6.3e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AAAP01003629.1_4 - 0.00013 21.3 0.0 0.00096 18.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein nos_propeller PF18764.1 AAAP01003630.1_1 - 1.4e-38 130.6 0.3 2.3e-36 123.5 0.2 2.6 2 0 0 2 2 2 2 Nitrous oxide reductase propeller repeat Cupredoxin_1 PF13473.6 AAAP01003630.1_1 - 9.3e-08 32.1 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain COX2 PF00116.20 AAAP01003630.1_1 - 0.00047 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Copper-bind PF00127.20 AAAP01003630.1_1 - 0.079 13.4 0.7 0.52 10.8 0.0 2.6 3 0 0 3 3 3 0 Copper binding proteins, plastocyanin/azurin family HEPN PF05168.14 AAAP01003630.1_1 - 0.24 11.5 0.9 0.55 10.4 0.9 1.6 1 0 0 1 1 1 0 HEPN domain Cytochrom_C PF00034.21 AAAP01003630.1_2 - 2.5e-24 86.2 1.3 1.6e-11 45.2 0.3 2.5 2 0 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003630.1_2 - 1.1e-16 60.9 2.1 1.3e-08 35.1 0.2 2.4 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DUF3365 PF11845.8 AAAP01003630.1_2 - 0.0013 19.1 3.0 0.72 10.2 0.1 2.6 1 1 1 3 3 3 2 Protein of unknown function (DUF3365) Cytochrome_C7 PF14522.6 AAAP01003630.1_2 - 0.0065 16.4 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003630.1_2 - 0.015 15.1 0.8 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Haem_bd PF14376.6 AAAP01003630.1_2 - 0.016 15.2 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Haem-binding domain DHOR PF06537.11 AAAP01003630.1_2 - 0.022 13.4 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Di-haem oxidoreductase, putative peroxidase FixO PF02433.15 AAAP01003630.1_2 - 0.032 13.7 0.1 2.1 7.7 0.0 2.4 1 1 2 3 3 3 0 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_c3_2 PF14537.6 AAAP01003630.1_2 - 0.064 13.7 0.1 12 6.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c3 DUF2312 PF10073.9 AAAP01003630.1_2 - 0.093 12.4 0.9 1.4 8.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1924 PF09086.11 AAAP01003630.1_2 - 0.11 12.9 2.6 2.8 8.4 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1924) PSCyt1 PF07635.11 AAAP01003630.1_2 - 0.62 10.7 3.3 11 6.6 0.1 2.6 2 0 0 2 2 2 0 Planctomycete cytochrome C Cytochrom_C PF00034.21 AAAP01003630.1_3 - 9.3e-17 62.0 1.1 5.7e-08 33.8 0.1 2.7 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003630.1_3 - 1.5e-13 50.8 1.9 2.8e-06 27.5 0.2 2.5 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 AAAP01003630.1_3 - 0.0036 17.0 0.2 0.026 14.3 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 AAAP01003630.1_3 - 0.0057 16.4 2.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 AAAP01003630.1_3 - 0.015 15.3 0.3 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C1 PF02167.15 AAAP01003630.1_3 - 0.03 14.0 0.0 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C1 family Cytochrom_NNT PF03264.14 AAAP01003630.1_3 - 0.081 12.6 0.2 11 5.7 0.0 2.1 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Cytochrome-c551 PF10643.9 AAAP01003630.1_3 - 0.18 11.4 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 MarC PF01914.17 AAAP01003630.1_3 - 0.19 11.1 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein tRNA-synt_1g PF09334.11 AAAP01003631.1_1 - 2.1e-50 171.6 0.0 2.6e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAAP01003631.1_1 - 9e-15 53.9 0.0 1.1e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAAP01003631.1_1 - 2.5e-05 24.3 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AAAP01003631.1_1 - 0.0005 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAAP01003631.1_1 - 0.06 12.2 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) TatD_DNase PF01026.21 AAAP01003631.1_2 - 6.1e-80 268.3 0.0 6.8e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Lactamase_B_2 PF12706.7 AAAP01003631.1_3 - 1.5e-38 132.4 0.9 1.8e-38 132.1 0.9 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01003631.1_3 - 4.5e-12 46.4 2.3 1.1e-11 45.2 2.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AAAP01003631.1_3 - 0.00015 21.7 0.3 0.00023 21.1 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Na_H_antiport_1 PF06965.12 AAAP01003631.1_4 - 1.6e-135 451.8 27.2 1.8e-135 451.6 27.2 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 Transglut_core PF01841.19 AAAP01003631.1_6 - 1.8e-13 50.9 0.4 2.1e-13 50.7 0.4 1.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily MlaA PF04333.13 AAAP01003632.1_1 - 8.4e-63 211.6 0.0 1e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 MlaA lipoprotein HATPase_c PF02518.26 AAAP01003632.1_2 - 3.6e-21 75.8 0.0 2.3e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003632.1_2 - 9.1e-21 74.2 1.6 2.5e-11 43.8 0.0 3.1 2 1 1 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01003632.1_2 - 3.9e-14 52.8 0.0 4.1e-06 27.0 0.0 4.0 2 2 1 3 3 3 2 PAS domain PAS PF00989.25 AAAP01003632.1_2 - 9e-11 41.8 0.0 7.5e-09 35.6 0.0 2.9 2 1 0 2 2 2 1 PAS fold HisKA PF00512.25 AAAP01003632.1_2 - 6.9e-08 32.4 0.6 6e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003632.1_2 - 7.6e-08 32.2 0.0 4e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain HATPase_c_2 PF13581.6 AAAP01003632.1_2 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_3 PF08447.12 AAAP01003632.1_2 - 0.026 14.8 0.0 0.087 13.1 0.0 1.9 1 1 0 1 1 1 0 PAS fold PAS_7 PF12860.7 AAAP01003632.1_2 - 0.069 13.3 0.0 0.66 10.1 0.0 2.4 2 0 0 2 2 2 0 PAS fold YceI PF04264.13 AAAP01003632.1_3 - 1.5e-44 152.1 2.5 1.8e-44 151.8 2.5 1.1 1 0 0 1 1 1 1 YceI-like domain Ni_hydr_CYTB PF01292.20 AAAP01003632.1_4 - 1.4e-27 96.5 13.7 1.6e-27 96.3 13.7 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF2231 PF09990.9 AAAP01003632.1_4 - 0.00045 20.6 5.2 0.044 14.2 0.2 2.3 1 1 0 2 2 2 2 Predicted membrane protein (DUF2231) Cytochrom_B561 PF03188.16 AAAP01003632.1_4 - 0.00079 19.6 2.5 0.0017 18.5 0.1 2.3 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 Nramp PF01566.18 AAAP01003632.1_4 - 0.076 12.0 3.0 0.21 10.5 3.1 1.7 1 1 0 1 1 1 0 Natural resistance-associated macrophage protein DUF2269 PF10027.9 AAAP01003632.1_4 - 2.9 7.9 14.9 2.8 8.0 1.0 3.1 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2269) YceI PF04264.13 AAAP01003632.1_5 - 3.3e-29 102.3 0.0 3.9e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 YceI-like domain Chromate_transp PF02417.15 AAAP01003633.1_1 - 8.4e-25 87.7 10.7 9.9e-25 87.5 10.7 1.0 1 0 0 1 1 1 1 Chromate transporter MFS_1_like PF12832.7 AAAP01003633.1_3 - 3.3e-54 184.2 13.5 6.7e-54 183.2 13.5 1.4 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 AAAP01003633.1_3 - 2.9e-16 59.3 10.7 2.1e-09 36.6 3.5 2.0 2 0 0 2 2 2 2 LacY proton/sugar symporter Nuc_H_symport PF03825.16 AAAP01003633.1_3 - 5.1e-12 45.5 11.7 6.7e-12 45.1 11.7 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1 PF07690.16 AAAP01003633.1_3 - 8.6e-11 41.3 55.0 8.8e-09 34.7 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YdjC PF04794.12 AAAP01003633.1_4 - 3.8e-45 154.7 0.0 4.3e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein Lipase_GDSL_2 PF13472.6 AAAP01003633.1_5 - 7.2e-09 36.3 0.6 1.9e-08 34.9 0.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ALGX PF16822.5 AAAP01003633.1_5 - 0.22 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Resolvase PF00239.21 AAAP01003634.1_1 - 9.8e-31 106.8 0.8 1.1e-30 106.7 0.8 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain Transposase_20 PF02371.16 AAAP01003634.1_2 - 7.3e-24 83.9 0.4 1.9e-23 82.6 0.4 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAAP01003634.1_2 - 1.7e-15 57.2 0.0 3.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Transposase GDP_Man_Dehyd PF16363.5 AAAP01003635.1_2 - 1.5e-50 172.5 0.0 1.8e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003635.1_2 - 1.6e-50 171.9 0.0 1.8e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAAP01003635.1_2 - 2.2e-12 46.6 0.0 2.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003635.1_2 - 6.1e-10 38.7 0.0 7.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AAAP01003635.1_2 - 2.6e-05 23.8 0.0 8.8e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 AAAP01003635.1_2 - 2.7e-05 23.5 0.0 0.00016 20.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003635.1_2 - 0.00012 21.4 0.1 0.00096 18.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 AAAP01003635.1_2 - 0.00034 20.6 0.1 0.00085 19.3 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003635.1_2 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding POR PF01558.18 AAAP01003635.1_3 - 2.1e-11 44.2 0.2 3.8e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 AAAP01003635.1_3 - 6.2e-06 26.1 0.1 2.7e-05 24.0 0.5 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.6 AAAP01003635.1_3 - 0.13 12.4 3.5 10 6.3 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain OmpA PF00691.20 AAAP01003636.1_1 - 1.6e-18 66.9 1.0 1.6e-18 66.9 1.0 1.7 2 0 0 2 2 2 1 OmpA family DIM PF08194.12 AAAP01003636.1_1 - 0.11 12.7 0.6 0.25 11.6 0.6 1.6 1 0 0 1 1 1 0 DIM protein Usp PF00582.26 AAAP01003636.1_2 - 3.1e-09 37.5 0.7 8.4e-05 23.1 0.2 2.5 2 0 0 2 2 2 2 Universal stress protein family PseudoU_synth_2 PF00849.22 AAAP01003636.1_3 - 6.9e-31 107.5 0.0 8.6e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase ACR_tran PF00873.19 AAAP01003636.1_4 - 1.3e-19 69.5 12.0 1.4e-19 69.4 12.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family NCU-G1 PF15065.6 AAAP01003636.1_4 - 0.048 12.6 1.3 0.06 12.3 1.3 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Pterin_bind PF00809.22 AAAP01003637.1_1 - 4.2e-49 167.4 0.0 6.4e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 AAAP01003637.1_1 - 5.4e-24 84.4 0.5 3.1e-23 82.0 0.1 2.4 2 0 0 2 2 2 1 B12 binding domain MtrH PF02007.18 AAAP01003637.1_1 - 0.00057 19.1 0.1 0.00088 18.5 0.1 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit S-methyl_trans PF02574.16 AAAP01003637.1_2 - 8.7e-76 255.2 0.0 1e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase MTHFR PF02219.17 AAAP01003637.1_3 - 7.2e-97 324.2 0.0 8.8e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_11 PF08241.12 AAAP01003637.1_4 - 2.1e-23 82.8 0.0 6.1e-23 81.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003637.1_4 - 7.9e-23 80.9 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003637.1_4 - 3.4e-21 75.7 0.0 4.4e-20 72.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003637.1_4 - 3.8e-18 65.9 0.0 5.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HTH_5 PF01022.20 AAAP01003637.1_4 - 1.4e-16 60.0 1.0 3.2e-16 58.9 1.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Methyltransf_12 PF08242.12 AAAP01003637.1_4 - 2.4e-15 57.1 0.0 6.4e-15 55.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003637.1_4 - 1.9e-12 47.0 0.0 2.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HTH_20 PF12840.7 AAAP01003637.1_4 - 1.9e-11 43.9 3.6 1.9e-11 43.9 3.6 2.4 3 0 0 3 3 2 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01003637.1_4 - 5.7e-09 35.7 3.5 2.2e-08 33.9 1.0 3.0 2 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 AAAP01003637.1_4 - 9.4e-08 31.5 0.8 2e-07 30.4 0.8 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MetW PF07021.12 AAAP01003637.1_4 - 2.5e-06 27.2 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AAAP01003637.1_4 - 2.6e-06 27.1 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TrmB PF01978.19 AAAP01003637.1_4 - 2.7e-05 24.0 0.0 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAAP01003637.1_4 - 7.3e-05 22.6 0.3 0.00016 21.5 0.3 1.5 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 AAAP01003637.1_4 - 0.00013 22.0 0.1 0.00029 20.8 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_IclR PF09339.10 AAAP01003637.1_4 - 0.00027 20.7 1.2 0.0021 17.8 1.2 2.7 2 1 0 2 2 2 1 IclR helix-turn-helix domain NodS PF05401.11 AAAP01003637.1_4 - 0.00041 20.0 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) HTH_23 PF13384.6 AAAP01003637.1_4 - 0.0017 18.1 0.1 0.02 14.7 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain PCMT PF01135.19 AAAP01003637.1_4 - 0.0045 16.8 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HTH_Crp_2 PF13545.6 AAAP01003637.1_4 - 0.0054 16.7 0.4 0.03 14.3 0.3 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 AAAP01003637.1_4 - 0.011 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 AAAP01003637.1_4 - 0.021 14.8 0.1 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4423 PF14394.6 AAAP01003637.1_4 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_34 PF13601.6 AAAP01003637.1_4 - 0.066 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 AAAP01003637.1_4 - 0.12 12.9 0.3 0.48 10.9 0.0 2.2 2 0 0 2 2 1 0 Winged helix DNA-binding domain CheR PF01739.18 AAAP01003637.1_4 - 0.19 11.2 0.0 0.48 9.9 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Patatin PF01734.22 AAAP01003637.1_5 - 9.9e-20 71.6 1.1 2.3e-19 70.4 1.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase GcpE PF04551.14 AAAP01003637.1_6 - 1.1e-18 67.5 0.4 1.2e-18 67.4 0.4 1.0 1 0 0 1 1 1 1 GcpE protein BCA_ABC_TP_C PF12399.8 AAAP01003638.1_1 - 2.7e-09 36.7 0.2 4.8e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter ABC_tran PF00005.27 AAAP01003638.1_1 - 2.5e-06 28.0 0.0 4.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003638.1_1 - 0.0046 16.8 0.0 0.0056 16.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AAAP01003638.1_2 - 2.9e-25 89.4 0.0 4.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003638.1_2 - 6.2e-07 29.5 0.6 0.0018 18.2 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003638.1_2 - 0.00023 20.7 0.2 0.031 13.7 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 AAAP01003638.1_2 - 0.012 16.0 0.0 0.025 15.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01003638.1_2 - 0.038 13.7 0.1 0.081 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003638.1_2 - 0.041 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 AAAP01003638.1_2 - 0.062 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 AAAP01003638.1_2 - 0.087 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 AAAP01003638.1_2 - 0.1 11.8 0.4 0.21 10.7 0.4 1.5 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 AAAP01003638.1_2 - 0.11 12.6 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 AAAP01003638.1_2 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NDK PF00334.19 AAAP01003638.1_2 - 0.12 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Nucleoside diphosphate kinase AAA_16 PF13191.6 AAAP01003638.1_2 - 0.13 12.7 0.2 0.2 12.1 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAAP01003638.1_2 - 0.13 11.8 0.1 0.28 10.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003638.1_2 - 0.25 11.6 0.7 1 9.6 0.7 2.0 1 1 0 1 1 1 0 AAA domain Peripla_BP_6 PF13458.6 AAAP01003638.1_3 - 4.7e-18 65.9 0.1 5.7e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003638.1_3 - 0.00033 19.8 0.1 0.00039 19.5 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Glyco_hydro_62 PF03664.13 AAAP01003638.1_3 - 0.16 11.3 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 Peripla_BP_6 PF13458.6 AAAP01003638.1_4 - 5.6e-64 217.0 3.8 7.1e-64 216.6 3.8 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003638.1_4 - 1.4e-13 50.6 0.1 1.8e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain BPD_transp_2 PF02653.16 AAAP01003638.1_5 - 3.9e-39 134.5 43.5 4.5e-39 134.2 43.5 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01003638.1_6 - 1.2e-22 80.4 15.2 1.2e-22 80.4 15.2 1.3 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component ThrE PF06738.12 AAAP01003638.1_6 - 1.6 8.0 16.4 0.18 11.1 12.1 1.5 2 0 0 2 2 2 0 Putative threonine/serine exporter DUF222 PF02720.17 AAAP01003639.1_1 - 0.0081 15.7 0.2 0.0088 15.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HemY_N PF07219.13 AAAP01003639.1_2 - 1.6e-13 50.8 0.4 1.6e-13 50.8 0.4 3.5 5 0 0 5 5 5 1 HemY protein N-terminus TPR_9 PF13371.6 AAAP01003639.1_2 - 0.0009 19.3 5.0 0.0009 19.3 5.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003639.1_2 - 0.0012 19.3 15.3 0.018 15.5 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Rubredoxin_2 PF18073.1 AAAP01003639.1_2 - 0.024 14.4 7.3 0.045 13.5 7.3 1.4 1 0 0 1 1 1 0 Rubredoxin metal binding domain TPR_2 PF07719.17 AAAP01003639.1_2 - 0.072 13.2 3.1 5.7 7.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RanBP PF00641.18 AAAP01003639.1_2 - 0.1 11.9 3.7 0.26 10.6 3.7 1.7 1 1 0 1 1 1 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 AAAP01003639.1_2 - 0.49 10.2 1.7 1.1 9.1 1.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DDE_Tnp_1_2 PF13586.6 AAAP01003639.1_3 - 1.7e-21 76.4 0.1 1.9e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01003639.1_3 - 2.6e-10 40.3 1.9 1.1e-08 35.0 1.9 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003639.1_3 - 0.0092 15.7 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AAAP01003639.1_3 - 0.027 14.5 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain DUF4096 PF13340.6 AAAP01003639.1_4 - 3.4e-24 84.9 2.0 3.4e-24 84.9 2.0 1.7 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) Ribosomal_L15e PF00827.17 AAAP01003639.1_4 - 0.084 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L15 DDE_Tnp_1 PF01609.21 AAAP01003639.1_5 - 1.1e-07 31.7 0.1 1.3e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain OEP PF02321.18 AAAP01003640.1_1 - 1.3e-21 77.3 23.9 4.1e-12 46.3 7.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein HAUS2 PF15003.6 AAAP01003640.1_1 - 0.11 12.2 2.7 0.1 12.3 0.5 2.0 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 2 FRP PF18032.1 AAAP01003640.1_1 - 0.41 11.3 3.0 42 4.8 0.3 3.4 3 0 0 3 3 3 0 Photoprotection regulator fluorescence recovery protein DUF4347 PF14252.6 AAAP01003640.1_2 - 2e-71 239.1 13.1 1.1e-43 149.0 2.3 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4347) Big_9 PF17963.1 AAAP01003640.1_2 - 4.8e-07 30.4 11.3 4.8e-07 30.4 11.3 6.9 5 2 1 6 6 6 1 Bacterial Ig domain Cadherin_5 PF17892.1 AAAP01003640.1_2 - 5.9e-06 26.2 1.8 4.1e-05 23.5 1.8 2.6 1 0 0 1 1 1 1 Cadherin-like domain CPSase_L_D2 PF02786.17 AAAP01003641.1_1 - 4.9e-82 274.5 0.1 6.1e-82 274.2 0.1 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 AAAP01003641.1_1 - 3.9e-40 136.3 0.0 6.5e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AAAP01003641.1_1 - 3.3e-09 36.6 0.0 6.4e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAAP01003641.1_1 - 5.6e-08 32.5 0.0 8.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AAAP01003641.1_1 - 1.5e-05 25.1 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AAAP01003641.1_1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 AAAP01003641.1_1 - 0.032 14.0 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FeoC PF09012.10 AAAP01003641.1_2 - 2.1e-25 88.6 0.0 2.3e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_28 PF13518.6 AAAP01003641.1_2 - 0.0015 18.7 0.1 0.0029 17.7 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AAAP01003641.1_2 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.8 2 1 0 2 2 2 1 DeoR-like helix-turn-helix domain EutK_C PF16365.5 AAAP01003641.1_2 - 0.0092 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilization protein EutK C-terminus HTH_Tnp_ISL3 PF13542.6 AAAP01003641.1_2 - 0.08 12.4 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 AAAP01003641.1_2 - 0.092 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AAAP01003641.1_2 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain STAT_int PF02865.17 AAAP01003641.1_2 - 0.18 12.3 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 STAT protein, protein interaction domain Rrf2 PF02082.20 AAAP01003641.1_2 - 0.19 12.1 0.0 0.23 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator ANAPC2 PF08672.11 AAAP01003641.1_2 - 0.22 12.1 0.0 0.35 11.4 0.0 1.4 1 1 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 PcfK PF14058.6 AAAP01003641.1_2 - 0.24 11.7 0.2 0.23 11.7 0.2 1.3 1 1 0 1 1 1 0 PcfK-like protein Gate PF07670.14 AAAP01003641.1_3 - 7e-44 148.7 7.0 6.5e-34 116.6 0.3 2.4 2 0 0 2 2 2 2 Nucleoside recognition FeoB_C PF07664.12 AAAP01003641.1_3 - 1.5e-22 79.1 0.4 4.9e-22 77.4 0.4 2.0 1 0 0 1 1 1 1 Ferrous iron transport protein B C terminus DUF3267 PF11667.8 AAAP01003641.1_3 - 0.0013 19.0 0.8 0.0061 16.8 0.8 2.2 1 0 0 1 1 1 1 Putative zincin peptidase Glyco_transf_21 PF13506.6 AAAP01003642.1_3 - 2.5e-44 150.8 0.0 3.6e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 AAAP01003642.1_3 - 1e-22 81.2 0.0 1.4e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003642.1_3 - 4.2e-17 62.7 0.0 4.2e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AAAP01003642.1_3 - 3.1e-06 27.1 0.0 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 MlaC PF05494.12 AAAP01003642.1_4 - 2.2e-28 99.1 0.0 2.8e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 MlaC protein LPG_synthase_TM PF03706.13 AAAP01003642.1_5 - 2.6e-34 119.1 38.8 3.4e-34 118.8 38.8 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF4407 PF14362.6 AAAP01003642.1_5 - 7.2 5.9 8.1 12 5.1 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amidinotransf PF02274.17 AAAP01003642.1_6 - 0.00014 21.1 0.0 0.22 10.6 0.0 3.1 3 1 0 3 3 3 2 Amidinotransferase GST_N_3 PF13417.6 AAAP01003642.1_8 - 8.3e-18 64.6 0.0 1.9e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003642.1_8 - 5.9e-12 45.7 0.0 9.6e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01003642.1_8 - 3.6e-07 30.4 0.0 7.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003642.1_8 - 7.4e-07 29.1 4.0 1.8e-06 27.9 4.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 AAAP01003642.1_8 - 0.0011 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AAAP01003642.1_8 - 0.0029 17.8 0.2 0.007 16.6 0.1 1.6 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Chlorophyllase2 PF12740.7 AAAP01003642.1_9 - 1.2e-05 24.3 0.0 1.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 AAAP01003642.1_9 - 5e-05 23.3 0.2 8.3e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hemerythrin PF01814.23 AAAP01003643.1_1 - 2.3e-11 44.4 0.1 2.6e-11 44.2 0.1 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PriX PF18689.1 AAAP01003643.1_1 - 0.026 14.9 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Primase X Utp13 PF08625.11 AAAP01003643.1_1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain CheZ PF04344.13 AAAP01003643.1_2 - 3.2e-12 46.8 2.0 4.4e-10 39.8 0.1 2.3 1 1 1 2 2 2 2 Chemotaxis phosphatase, CheZ zf-C4H2 PF10146.9 AAAP01003643.1_2 - 0.0073 16.6 0.6 0.029 14.7 0.1 2.0 1 1 0 2 2 2 1 Zinc finger-containing protein MraZ PF02381.18 AAAP01003643.1_3 - 4.7e-15 55.3 0.0 3.7e-08 33.2 0.0 2.2 2 1 0 2 2 2 2 MraZ protein, putative antitoxin-like MazE_antitoxin PF04014.18 AAAP01003643.1_3 - 0.12 12.4 0.1 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Methyltransf_5 PF01795.19 AAAP01003643.1_4 - 4.4e-102 341.7 0.0 5.4e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 AAAP01003643.1_4 - 0.054 14.2 0.1 0.54 11.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF1192 PF06698.11 AAAP01003643.1_5 - 0.0027 17.7 0.2 0.005 16.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) FtsL PF04999.13 AAAP01003643.1_5 - 0.0032 17.4 0.0 0.0036 17.3 0.0 1.0 1 0 0 1 1 1 1 Cell division protein FtsL FAM196 PF15265.6 AAAP01003643.1_5 - 0.0096 15.5 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 FAM196 family DUF473 PF04322.12 AAAP01003643.1_5 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF473) BPD_transp_1 PF00528.22 AAAP01003644.1_1 - 1.5e-18 67.2 7.5 1.8e-18 66.9 7.5 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 AAAP01003644.1_1 - 0.11 13.0 7.4 0.056 13.9 1.8 2.0 2 0 0 2 2 2 0 FtsX-like permease family ABC_tran PF00005.27 AAAP01003644.1_2 - 1.6e-21 77.3 0.0 3.4e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003644.1_2 - 8e-10 39.0 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003644.1_2 - 0.00025 20.7 0.1 0.00045 19.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003644.1_2 - 0.00044 20.7 0.3 0.00079 19.8 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003644.1_2 - 0.0012 18.8 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 AAAP01003644.1_2 - 0.0017 18.6 0.0 0.0048 17.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 AAAP01003644.1_2 - 0.0021 18.3 0.0 0.0051 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003644.1_2 - 0.0094 16.1 0.4 0.036 14.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAAP01003644.1_2 - 0.011 16.2 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003644.1_2 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AAAP01003644.1_2 - 0.026 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 AAAP01003644.1_2 - 0.048 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 AAAP01003644.1_2 - 0.051 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 AAAP01003644.1_2 - 0.053 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AAAP01003644.1_2 - 0.061 12.9 0.7 0.13 11.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain DUF3666 PF12408.8 AAAP01003644.1_2 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase ATPase_2 PF01637.18 AAAP01003644.1_2 - 0.098 12.6 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AAAP01003644.1_2 - 0.14 12.7 0.0 0.2 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003644.1_2 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 AAAP01003644.1_2 - 0.21 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.22 AAAP01003644.1_2 - 0.32 10.2 0.1 0.46 9.6 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain ABC2_membrane PF01061.24 AAAP01003644.1_3 - 1.3e-30 106.4 18.9 1.3e-30 106.4 18.9 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01003644.1_3 - 4.8e-19 68.7 18.0 4.8e-19 68.7 18.0 1.4 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAAP01003644.1_3 - 1.6e-11 44.0 16.9 1.6e-11 44.0 16.9 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAAP01003644.1_3 - 0.048 13.6 8.3 0.11 12.4 8.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAAP01003644.1_3 - 0.11 12.0 6.7 0.25 10.9 6.7 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAAP01003644.1_4 - 7.5e-29 101.0 0.0 9.9e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01003644.1_4 - 5.3e-06 26.9 0.6 8.3e-06 26.3 0.6 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01003644.1_4 - 4.9e-05 23.3 0.8 0.0036 17.2 0.2 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003644.1_4 - 0.00011 21.9 0.1 0.00021 21.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAAP01003644.1_4 - 0.0012 18.3 0.1 0.071 12.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003644.1_4 - 0.0027 18.3 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003644.1_4 - 0.0032 17.4 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 AAAP01003644.1_4 - 0.0058 16.2 1.5 0.094 12.3 1.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01003644.1_4 - 0.0066 16.2 0.1 0.027 14.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003644.1_4 - 0.0067 16.7 0.2 0.078 13.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAAP01003644.1_4 - 0.023 14.3 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01003644.1_4 - 0.096 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 AAAP01003644.1_4 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AAAP01003644.1_4 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 AAAP01003644.1_4 - 0.17 11.9 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 AAAP01003644.1_4 - 0.32 9.6 0.1 0.43 9.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain Hairy_orange PF07527.13 AAAP01003644.1_4 - 2.6 8.3 5.7 0.93 9.8 0.5 2.5 2 0 0 2 2 2 0 Hairy Orange Lactonase PF10282.9 AAAP01003644.1_5 - 1.6e-08 34.2 0.0 4.8e-08 32.6 0.0 1.7 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AAAP01003644.1_5 - 2.2e-08 33.0 0.6 0.0013 17.4 0.1 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain NHL PF01436.21 AAAP01003644.1_5 - 2.3e-05 24.2 0.0 3 8.0 0.0 4.6 4 1 1 5 5 5 2 NHL repeat DUF2415 PF10313.9 AAAP01003644.1_5 - 0.011 15.6 0.1 3.2 7.8 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 AAAP01003644.1_5 - 0.044 14.1 0.4 14 6.1 0.1 3.4 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 AAAP01003644.1_5 - 0.13 11.1 0.1 2.8 6.7 0.0 2.3 2 1 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF347 PF03988.12 AAAP01003645.1_1 - 0.0057 16.8 0.4 0.0057 16.8 0.4 2.1 2 0 0 2 2 2 1 Repeat of Unknown Function (DUF347) Ribonuclease_T2 PF00445.18 AAAP01003645.1_2 - 6.8e-19 68.8 0.6 1.3e-18 67.9 0.6 1.4 1 1 0 1 1 1 1 Ribonuclease T2 family DUF3561 PF12084.8 AAAP01003645.1_4 - 0.018 15.1 1.2 0.021 14.8 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) Smim3 PF17307.2 AAAP01003645.1_4 - 0.023 14.2 0.7 0.025 14.0 0.7 1.2 1 0 0 1 1 1 0 Small integral membrane protein 3 DUF5325 PF17259.2 AAAP01003645.1_4 - 0.045 13.6 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5325) Radical_SAM PF04055.21 AAAP01003645.1_5 - 1.3e-20 74.4 0.0 2.5e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAAP01003645.1_5 - 9.1e-17 60.9 0.1 1.9e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 HemN C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAAP01003645.1_6 - 1.1e-24 86.2 0.0 1.4e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAAP01003645.1_6 - 6.2e-16 58.4 0.0 6.9e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 AAAP01003645.1_6 - 0.00083 19.5 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 APOBEC3 APOBEC_N PF08210.11 AAAP01003645.1_6 - 0.024 14.5 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain SNAD4 PF18750.1 AAAP01003645.1_6 - 0.041 14.0 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 AAAP01003645.1_6 - 0.044 13.9 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 AAAP01003645.1_6 - 0.061 13.4 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 SCP1201-deam PF14428.6 AAAP01003645.1_6 - 0.1 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 SCP1.201-like deaminase Bd3614-deam PF14439.6 AAAP01003645.1_6 - 0.15 12.2 2.7 0.33 11.0 0.7 2.2 2 1 1 3 3 3 0 Bd3614-like deaminase RuBisCO_large_N PF02788.16 AAAP01003645.1_7 - 7.4e-41 139.1 0.0 9.8e-41 138.7 0.0 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain RuBisCO_large PF00016.20 AAAP01003645.1_7 - 9.8e-09 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain HisKA PF00512.25 AAAP01003646.1_1 - 6.6e-19 67.7 0.1 6.3e-18 64.6 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AAAP01003646.1_1 - 6.4e-11 42.8 0.0 2.3e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01003646.1_1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PgpA PF04608.13 AAAP01003646.1_2 - 8.5e-48 162.0 5.0 9.6e-48 161.8 5.0 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A FGFR3_TM PF18123.1 AAAP01003646.1_2 - 0.15 11.6 0.2 0.15 11.6 0.2 2.0 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain CinA PF02464.17 AAAP01003646.1_3 - 2.7e-57 192.7 2.0 3.3e-57 192.4 2.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein TPP_enzyme_N PF02776.18 AAAP01003646.1_5 - 8.8e-35 119.8 0.0 1e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peptidase_M41 PF01434.18 AAAP01003647.1_2 - 0.00018 21.4 0.1 0.00024 21.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M41 KH_5 PF13184.6 AAAP01003647.1_2 - 0.044 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 NusA-like KH domain PTH2 PF01981.16 AAAP01003647.1_4 - 0.033 14.5 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 ROS_MUCR PF05443.11 AAAP01003647.1_5 - 1.1e-42 145.1 0.0 1.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein T2SS_PulS_OutS PF09691.10 AAAP01003647.1_5 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) zf-C2H2 PF00096.26 AAAP01003647.1_5 - 1.6 9.3 3.9 10 6.8 3.9 2.1 1 1 0 1 1 1 0 Zinc finger, C2H2 type Bac_DNA_binding PF00216.21 AAAP01003647.1_6 - 7.9e-32 109.3 0.1 8.7e-32 109.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003647.1_6 - 3e-06 27.3 0.0 3.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF2267 PF10025.9 AAAP01003647.1_6 - 0.0057 16.9 0.1 0.008 16.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) WYL PF13280.6 AAAP01003647.1_7 - 1.1e-09 38.5 0.0 1.6e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 WYL domain PHY PF00360.20 AAAP01003648.1_1 - 3.6e-40 137.2 0.1 6e-40 136.5 0.1 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 AAAP01003648.1_1 - 6.6e-20 71.7 0.0 1.3e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Heme_oxygenase PF01126.20 AAAP01003648.1_1 - 3.1e-12 46.7 0.0 2.9e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 Heme oxygenase HATPase_c_3 PF13589.6 AAAP01003648.1_1 - 0.035 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_4 PF02056.16 AAAP01003649.1_1 - 6.5e-44 149.7 0.0 8.2e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 AAAP01003649.1_1 - 9.3e-06 25.9 0.1 1.8e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain DUF4412 PF14371.6 AAAP01003649.1_1 - 0.17 11.7 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Glucosamine_iso PF01182.20 AAAP01003649.1_2 - 7.1e-22 78.4 0.0 1.3e-21 77.5 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF883 PF05957.13 AAAP01003649.1_2 - 0.087 13.4 2.2 0.14 12.7 0.4 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Methyltransf_23 PF13489.6 AAAP01003649.1_3 - 1.1e-09 38.3 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003649.1_3 - 8.5e-09 36.0 0.0 3.1e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003649.1_3 - 5.8e-06 26.9 0.0 1.4e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003649.1_3 - 2.8e-05 24.8 0.0 6.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FeoA PF04023.14 AAAP01003649.1_4 - 1.9e-17 63.2 0.1 2.2e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 FeoA domain DUF4846 PF16138.5 AAAP01003649.1_4 - 0.072 12.6 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (4846) FeoB_N PF02421.18 AAAP01003649.1_5 - 3.6e-66 221.5 0.1 4.5e-66 221.2 0.1 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 AAAP01003649.1_5 - 3.8e-19 68.8 0.0 6.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01003649.1_5 - 0.00018 21.5 0.1 0.47 10.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 AAAP01003649.1_5 - 0.00048 19.6 0.0 0.00065 19.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 AAAP01003649.1_5 - 0.00056 19.5 0.1 0.56 9.7 0.0 2.6 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 AAAP01003649.1_5 - 0.0034 17.2 0.6 0.076 12.8 0.1 2.3 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AAAP01003649.1_5 - 0.0085 16.6 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 AAAP01003649.1_5 - 0.014 15.4 0.1 0.79 9.8 0.0 2.2 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 AAAP01003649.1_5 - 0.076 12.8 0.1 0.49 10.1 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation BPD_transp_2 PF02653.16 AAAP01003650.1_1 - 8.3e-20 71.1 15.9 9.9e-20 70.8 15.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component RTX PF02382.15 AAAP01003650.1_1 - 0.83 9.3 4.0 1 9.0 4.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein BPD_transp_2 PF02653.16 AAAP01003650.1_2 - 2.2e-37 128.7 37.9 3e-37 128.2 37.9 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Peripla_BP_6 PF13458.6 AAAP01003650.1_3 - 1e-69 235.8 2.4 1.2e-69 235.6 2.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003650.1_3 - 0.00095 18.3 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain ABC_tran PF00005.27 AAAP01003650.1_4 - 2.2e-26 93.0 0.0 3.5e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003650.1_4 - 1.3e-10 41.6 0.3 6.8e-06 26.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003650.1_4 - 2.3e-05 25.0 0.0 3.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003650.1_4 - 0.00012 21.6 0.1 0.0011 18.5 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003650.1_4 - 0.00047 19.8 0.3 0.00089 18.9 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AAAP01003650.1_4 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAAP01003650.1_4 - 0.0044 16.9 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 AAAP01003650.1_4 - 0.0069 16.1 1.0 0.023 14.4 1.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01003650.1_4 - 0.0094 15.7 0.0 0.0094 15.7 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003650.1_4 - 0.057 13.7 0.3 0.28 11.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003650.1_4 - 0.063 13.2 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 AAAP01003650.1_4 - 0.096 12.2 0.4 0.9 9.1 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAAP01003650.1_4 - 0.15 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.28 AAAP01003650.1_5 - 4.7e-05 22.2 0.0 6.4e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HisKA PF00512.25 AAAP01003651.1_1 - 9.2e-18 64.0 0.7 3.2e-16 59.1 0.1 3.1 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003651.1_1 - 3e-06 27.4 0.1 5.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003651.1_1 - 2.3e-05 24.3 0.2 6.5e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003651.1_1 - 0.00011 22.1 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003651.1_1 - 0.00021 21.5 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain BORCS6 PF10157.9 AAAP01003651.1_1 - 0.095 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Cortex-I_coil PF09304.10 AAAP01003651.1_1 - 0.27 11.5 1.7 28 5.0 0.1 2.8 2 1 1 3 3 3 0 Cortexillin I, coiled coil Sigma54_activat PF00158.26 AAAP01003651.1_2 - 1.1e-67 227.0 0.0 1.7e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAAP01003651.1_2 - 7.8e-22 77.6 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAAP01003651.1_2 - 2.3e-19 69.9 0.0 1.7e-18 67.0 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01003651.1_2 - 1.5e-09 37.5 2.1 3.4e-09 36.3 2.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAAP01003651.1_2 - 1.8e-07 31.2 0.0 5.8e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01003651.1_2 - 2.2e-05 24.9 0.0 4.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_50 PF18024.1 AAAP01003651.1_2 - 0.0052 16.4 0.2 0.015 14.9 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Mg_chelatase PF01078.21 AAAP01003651.1_2 - 0.019 14.4 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AAAP01003651.1_2 - 0.026 14.6 0.0 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) MCM PF00493.23 AAAP01003651.1_2 - 0.2 10.7 0.0 0.98 8.5 0.0 2.0 1 1 0 1 1 1 0 MCM P-loop domain Lactamase_B_3 PF13483.6 AAAP01003651.1_3 - 3.9e-14 52.9 0.0 6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AAAP01003651.1_3 - 1e-11 44.7 0.2 1.4e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MCPsignal PF00015.21 AAAP01003651.1_4 - 1.6e-13 50.9 0.5 2.4e-13 50.2 0.5 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAAP01003651.1_4 - 1.8e-13 50.9 0.0 2.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Cache domain Mem_trans PF03547.18 AAAP01003651.1_5 - 0.00068 18.1 0.6 0.00075 18.0 0.6 1.0 1 0 0 1 1 1 1 Membrane transport protein PAS_4 PF08448.10 AAAP01003652.1_1 - 7.6e-32 109.8 0.1 4.4e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01003652.1_1 - 1.1e-16 60.9 0.0 1.5e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003652.1_1 - 2.7e-11 43.6 0.0 1.9e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AAAP01003652.1_1 - 8.7e-07 29.1 0.0 4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003652.1_1 - 1.7e-06 27.9 0.1 0.021 14.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_10 PF13596.6 AAAP01003652.1_1 - 1.6e-05 25.4 0.0 0.018 15.6 0.0 2.3 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 AAAP01003652.1_1 - 3.6e-05 23.7 2.2 0.0009 19.2 0.1 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 AAAP01003652.1_1 - 0.00023 21.3 0.1 0.0097 16.1 0.0 2.9 2 2 0 2 2 2 1 PAS fold H_kinase_N PF12282.8 AAAP01003652.1_1 - 0.12 12.4 0.0 0.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Signal transduction histidine kinase Peripla_BP_6 PF13458.6 AAAP01003652.1_2 - 4.6e-83 279.7 6.8 5.7e-83 279.4 6.8 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003652.1_2 - 1.8e-14 53.6 0.4 1e-13 51.1 0.4 1.8 1 1 0 1 1 1 1 Periplasmic binding protein domain DUF218 PF02698.17 AAAP01003652.1_3 - 2.4e-22 79.4 0.0 3.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain T3SS_LEE_assoc PF13327.6 AAAP01003652.1_3 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system subunit SLT_2 PF13406.6 AAAP01003652.1_4 - 1.3e-108 362.7 0.0 1.5e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AAAP01003652.1_4 - 0.0063 17.0 0.1 0.019 15.4 0.0 1.9 2 1 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT PF01464.20 AAAP01003652.1_4 - 0.045 13.4 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Transglycosylase SLT domain DPBB_1 PF03330.18 AAAP01003652.1_5 - 3.8e-24 84.8 0.0 7.6e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase SPOR PF05036.13 AAAP01003652.1_5 - 2.9e-13 50.0 0.4 1.2e-12 48.0 0.2 2.0 2 0 0 2 2 2 1 Sporulation related domain Peptidase_S11 PF00768.20 AAAP01003652.1_6 - 3.1e-13 49.7 0.0 3.6e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_S13 PF02113.15 AAAP01003652.1_6 - 7e-05 21.7 0.1 8.3e-05 21.5 0.1 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family PgpA PF04608.13 AAAP01003652.1_6 - 0.01 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A T4SS-DNA_transf PF02534.14 AAAP01003653.1_3 - 4.4e-51 174.1 0.0 6.1e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AAAP01003653.1_3 - 2.1e-21 76.2 0.0 3.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AAAP01003653.1_3 - 4.2e-14 52.3 0.0 5.6e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain RelB PF04221.12 AAAP01003653.1_6 - 1.4e-09 37.8 0.0 3.7e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 RelB antitoxin CbiJ PF02571.14 AAAP01003654.1_1 - 1.9e-24 86.4 0.0 2.1e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK CbiD PF01888.17 AAAP01003654.1_2 - 2.4e-87 292.4 0.4 5.9e-87 291.1 0.1 1.7 2 0 0 2 2 2 1 CbiD Response_reg PF00072.24 AAAP01003654.1_3 - 9e-24 83.8 0.1 1.1e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003654.1_4 - 5.5e-24 84.8 0.0 1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAAP01003654.1_4 - 1.7e-22 79.6 0.0 1.5e-14 54.1 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 AAAP01003654.1_4 - 3e-21 75.5 0.0 1.5e-14 53.9 0.0 3.6 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AAAP01003654.1_4 - 6.1e-17 61.9 4.5 2.9e-08 34.0 0.1 3.5 3 1 0 3 3 3 2 PAS fold HisKA PF00512.25 AAAP01003654.1_4 - 2.1e-13 50.1 0.1 1.2e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003654.1_4 - 6.6e-11 42.4 1.1 2.6e-10 40.5 1.1 2.1 1 0 0 1 1 1 1 HAMP domain PAS_8 PF13188.7 AAAP01003654.1_4 - 5.3e-09 35.9 0.2 0.0029 17.6 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AAAP01003654.1_4 - 3.8e-07 30.3 0.1 0.046 14.0 0.0 3.8 2 1 0 2 2 2 2 PAS fold HATPase_c_5 PF14501.6 AAAP01003654.1_4 - 0.00067 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01003654.1_4 - 0.061 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rbx_binding PF18113.1 AAAP01003654.1_4 - 0.15 11.8 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain SR-25 PF10500.9 AAAP01003655.1_1 - 0.0019 17.9 5.6 0.0022 17.6 5.6 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4647 PF15504.6 AAAP01003655.1_1 - 0.091 11.9 2.6 0.11 11.6 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Preseq_ALAS PF09029.10 AAAP01003655.1_1 - 0.34 11.4 5.9 0.43 11.1 5.9 1.2 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence FAM199X PF15814.5 AAAP01003655.1_1 - 0.74 8.8 5.3 0.87 8.6 5.3 1.0 1 0 0 1 1 1 0 Protein family FAM199X RNA_pol_Rpc4 PF05132.14 AAAP01003655.1_1 - 1.1 9.7 8.3 1.2 9.5 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 ATP-synt_B PF00430.18 AAAP01003655.1_1 - 9.2 6.4 12.1 11 6.1 12.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) FliD_C PF07195.12 AAAP01003655.1_2 - 3.5e-14 52.8 0.2 6.6e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Flagellin_IN PF07196.13 AAAP01003655.1_2 - 8.9e-05 22.6 0.3 8.9e-05 22.6 0.3 2.9 4 0 0 4 4 4 1 Flagellin hook IN motif FliD_N PF02465.18 AAAP01003655.1_2 - 4.4 8.1 11.1 4.1e+02 1.8 9.7 3.8 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus R2K_3 PF14243.6 AAAP01003655.1_4 - 0.16 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Pyridoxal_deC PF00282.19 AAAP01003655.1_5 - 2.5e-09 36.3 0.0 3.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DDE_Tnp_ISL3 PF01610.17 AAAP01003656.1_1 - 1.8e-23 83.5 0.0 1.1e-14 54.8 0.0 2.6 3 0 0 3 3 3 2 Transposase zf-ISL3 PF14690.6 AAAP01003656.1_1 - 9.9e-08 32.5 2.0 9.9e-08 32.5 2.0 2.8 3 0 0 3 3 3 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HBM PF16591.5 AAAP01003656.1_2 - 9.7e-05 21.9 4.0 0.00017 21.1 4.0 1.4 1 1 0 1 1 1 1 Helical bimodular sensor domain 4HB_MCP_1 PF12729.7 AAAP01003656.1_2 - 0.0012 18.5 0.1 0.0028 17.2 0.1 1.6 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF2205 PF10224.9 AAAP01003656.1_2 - 0.0018 18.2 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Short coiled-coil protein Syntaxin-6_N PF09177.11 AAAP01003656.1_2 - 0.12 13.0 0.2 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Glycos_transf_2 PF00535.26 AAAP01003657.1_1 - 5.3e-22 78.4 0.0 7.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003657.1_1 - 8.4e-12 45.5 0.0 2.3e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003657.1_1 - 1.6e-07 31.1 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003657.1_1 - 5.1e-06 26.5 6.9 4.4e-05 23.5 6.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 AAAP01003657.1_1 - 0.022 14.4 0.1 0.44 10.2 0.0 2.2 1 1 1 2 2 2 0 N-terminal domain of galactosyltransferase Autotransporter PF03797.19 AAAP01003657.1_2 - 2.3e-27 96.3 22.7 2.3e-27 96.3 22.7 1.5 2 0 0 2 2 2 1 Autotransporter beta-domain OMP_b-brl PF13505.6 AAAP01003657.1_2 - 6 7.0 33.6 0.64 10.1 18.4 2.4 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain Hist_deacetyl PF00850.19 AAAP01003658.1_1 - 0.042 13.3 0.1 0.047 13.2 0.1 1.0 1 0 0 1 1 1 0 Histone deacetylase domain FtsJ PF01728.19 AAAP01003658.1_2 - 3.8e-23 82.5 0.0 4.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 AAAP01003658.1_2 - 9.5e-08 31.6 0.1 2.3e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 S4 domain Methyltransf_11 PF08241.12 AAAP01003658.1_2 - 0.0017 18.9 0.0 0.0028 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003658.1_2 - 0.0059 17.3 0.0 0.0098 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003658.1_2 - 0.059 14.1 0.0 0.1 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SRAP PF02586.14 AAAP01003658.1_3 - 1.3e-23 83.7 0.0 2.1e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Trans_reg_C PF00486.28 AAAP01003658.1_5 - 2.9e-29 100.9 0.1 4.9e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AAAP01003658.1_5 - 1.9e-22 79.5 0.0 3.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003658.1_6 - 7.9e-18 65.0 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003658.1_6 - 1.2e-09 38.4 0.4 1.2e-09 38.4 0.4 2.6 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 AAAP01003658.1_6 - 5.9e-06 26.2 3.4 8.9e-06 25.7 1.3 2.4 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain Prominin PF05478.11 AAAP01003658.1_6 - 0.0012 16.9 0.0 0.0018 16.3 0.0 1.1 1 0 0 1 1 1 1 Prominin HATPase_c_2 PF13581.6 AAAP01003658.1_6 - 0.002 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2937 PF11157.8 AAAP01003658.1_6 - 0.046 13.4 1.1 0.08 12.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) HATPase_c_3 PF13589.6 AAAP01003658.1_6 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF948 PF06103.11 AAAP01003658.1_6 - 0.12 12.6 0.0 2.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4010 PF13194.6 AAAP01003659.1_1 - 4.1 7.0 14.6 0.44 10.2 4.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4010) Polysacc_synt_3 PF13440.6 AAAP01003659.1_2 - 4e-07 29.5 3.3 4e-07 29.5 3.3 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AAAP01003659.1_2 - 1.1e-05 24.9 11.5 1.1e-05 24.9 11.5 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Metallophos_2 PF12850.7 AAAP01003659.1_3 - 8.2e-08 32.6 0.0 1.6e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAAP01003659.1_3 - 3.8e-07 30.8 0.1 1.9e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Lon_2 PF13337.6 AAAP01003660.1_2 - 1.4e-106 356.8 0.0 1.9e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease MIT_C PF16565.5 AAAP01003660.1_2 - 6.2e-41 139.7 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT N6_Mtase PF02384.16 AAAP01003660.1_2 - 6.1e-06 25.7 0.0 0.024 13.9 0.0 2.3 2 0 0 2 2 2 2 N-6 DNA Methylase Eco57I PF07669.11 AAAP01003660.1_2 - 0.00028 21.4 0.0 0.0014 19.1 0.0 2.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase IstB_IS21 PF01695.17 AAAP01003660.1_2 - 0.07 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PP_kinase_C PF13090.6 AAAP01003661.1_1 - 2.6e-60 202.8 0.0 3.3e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 2 PP_kinase_C_1 PF17941.1 AAAP01003661.1_1 - 4.8e-23 81.5 0.1 1.8e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PLDc_2 PF13091.6 AAAP01003661.1_1 - 0.001 18.9 0.0 0.082 12.8 0.0 2.9 2 1 0 2 2 2 1 PLD-like domain Ppx-GppA PF02541.16 AAAP01003661.1_2 - 8.5e-43 146.8 0.0 1.1e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DDR PF08841.10 AAAP01003661.1_2 - 0.00039 19.5 0.3 0.00075 18.6 0.3 1.4 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DUF188 PF02639.14 AAAP01003661.1_3 - 9.2e-45 151.5 0.0 1e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 PIN_9 PF18477.1 AAAP01003661.1_3 - 0.14 12.5 0.0 0.26 11.6 0.0 1.7 1 1 0 1 1 1 0 PIN like domain CxxCxxCC PF03692.15 AAAP01003661.1_4 - 9e-08 32.7 0.6 1.4e-07 32.1 0.6 1.3 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DNA_pol_A_exo1 PF01612.20 AAAP01003661.1_5 - 5.7e-34 117.3 0.0 8.1e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 AAAP01003661.1_5 - 1.3e-20 73.1 0.4 4.8e-20 71.3 0.2 2.2 2 0 0 2 2 2 1 HRDC domain Response_reg PF00072.24 AAAP01003661.1_6 - 5.8e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 2 0 0 2 2 2 1 Response regulator receiver domain tRNA_anti-codon PF01336.25 AAAP01003661.1_7 - 3.3e-13 49.4 0.0 4.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Response_reg PF00072.24 AAAP01003662.1_1 - 4.4e-42 142.8 0.0 6.6e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003662.1_1 - 1.2e-28 99.8 0.0 2.4e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003662.1_1 - 3.5e-18 65.4 1.6 4e-17 62.0 0.1 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAAP01003662.1_1 - 1.4e-07 31.6 5.1 3e-07 30.6 3.6 2.3 2 0 0 2 2 2 1 Hpt domain FleQ PF06490.11 AAAP01003662.1_1 - 0.0035 17.7 0.0 0.87 10.0 0.0 2.6 2 0 0 2 2 2 2 Flagellar regulatory protein FleQ Response_reg PF00072.24 AAAP01003662.1_2 - 1.1e-19 70.7 0.0 1.2e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003662.1_3 - 1.7e-22 80.0 0.0 8.8e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAAP01003662.1_3 - 1.4e-12 47.7 0.0 3.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003662.1_3 - 1.2e-10 41.3 0.0 8.3e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003662.1_3 - 0.0015 18.8 0.1 0.0031 17.7 0.1 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAAP01003662.1_3 - 0.0021 18.0 0.0 0.0092 15.9 0.0 2.0 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAAP01003662.1_3 - 0.0043 16.9 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS PF00989.25 AAAP01003662.1_3 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF5518 PF17647.1 AAAP01003662.1_3 - 3.8 7.7 9.5 6.3 7.0 9.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5518) NUDIX PF00293.28 AAAP01003662.1_4 - 8e-19 68.0 0.5 9.5e-19 67.7 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AAAP01003662.1_4 - 0.0043 17.0 0.1 0.006 16.6 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain cNMP_binding PF00027.29 AAAP01003663.1_1 - 9.4e-12 44.9 0.1 6.6e-10 38.9 0.0 2.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 AAAP01003663.1_1 - 8.3e-08 32.0 0.1 1.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01003663.1_1 - 4.2e-07 30.2 0.1 8.4e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PEGA PF08308.11 AAAP01003663.1_2 - 0.039 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 PEGA domain Hemerythrin PF01814.23 AAAP01003663.1_3 - 1.8e-12 48.0 1.5 2.1e-12 47.8 1.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PMD PF10536.9 AAAP01003663.1_3 - 0.082 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Plant mobile domain Trypsin_2 PF13365.6 AAAP01003663.1_4 - 2.9e-18 67.2 0.1 4e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAAP01003663.1_4 - 7.9e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 AAAP01003663.1_4 - 0.023 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease MCPsignal PF00015.21 AAAP01003664.1_1 - 6.8e-19 68.3 22.6 9.1e-19 67.9 16.6 2.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003664.1_1 - 0.0071 16.6 8.1 0.45 10.8 0.6 3.2 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) Transcrip_act PF04949.13 AAAP01003664.1_1 - 0.01 15.7 0.2 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional activator HMMR_N PF15905.5 AAAP01003664.1_1 - 0.011 15.2 0.4 0.015 14.8 0.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal VWA_N PF08399.11 AAAP01003664.1_1 - 0.044 14.3 0.1 0.077 13.5 0.1 1.4 1 0 0 1 1 1 0 VWA N-terminal DUF5424 PF17462.2 AAAP01003664.1_1 - 0.06 13.3 0.4 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5424) Vps53_N PF04100.12 AAAP01003664.1_1 - 0.1 11.5 2.1 0.16 10.9 1.9 1.4 1 1 0 1 1 1 0 Vps53-like, N-terminal GldM_N PF12081.8 AAAP01003664.1_1 - 0.11 12.6 1.5 0.43 10.7 1.3 1.9 1 1 1 2 2 2 0 GldM N-terminal domain V_ATPase_I PF01496.19 AAAP01003664.1_1 - 0.11 10.4 0.5 0.16 9.9 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TACC_C PF05010.14 AAAP01003664.1_1 - 0.16 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BORCS7 PF16088.5 AAAP01003664.1_1 - 0.16 12.2 3.2 0.23 11.8 1.9 1.9 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Syntaxin-6_N PF09177.11 AAAP01003664.1_1 - 0.21 12.2 4.3 2.5 8.7 4.1 2.9 2 1 0 2 2 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 AAAP01003664.1_1 - 0.36 10.9 3.9 19 5.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG17 PF04108.12 AAAP01003664.1_1 - 0.37 9.9 5.2 1.3 8.1 1.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 Laminin_II PF06009.12 AAAP01003664.1_1 - 0.4 10.7 7.3 0.19 11.7 2.6 2.2 1 1 1 2 2 2 0 Laminin Domain II Laminin_I PF06008.14 AAAP01003664.1_1 - 0.46 10.2 7.2 2.6 7.7 4.0 2.1 1 1 1 2 2 2 0 Laminin Domain I Flagellin_C PF00700.21 AAAP01003664.1_1 - 0.71 10.3 8.4 0.12 12.7 0.9 2.8 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Filament PF00038.21 AAAP01003664.1_1 - 0.8 9.2 3.0 1.5 8.3 0.7 2.0 1 1 1 2 2 2 0 Intermediate filament protein T7SS_ESX_EspC PF10824.8 AAAP01003664.1_1 - 2 8.9 16.9 4.6 7.8 7.8 2.6 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF3450 PF11932.8 AAAP01003664.1_1 - 3.6 6.8 9.3 3.7 6.8 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) T3SSipB PF16535.5 AAAP01003664.1_1 - 4.2 7.8 12.6 7.5 7.0 7.0 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB SCAB_CC PF16712.5 AAAP01003664.1_1 - 8.3 6.2 10.7 3.9 7.3 2.4 2.1 1 1 1 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Se-cys_synth_N PF12390.8 AAAP01003664.1_2 - 0.14 12.4 0.0 12 6.2 0.0 2.1 2 0 0 2 2 2 0 Selenocysteine synthase N terminal SlyX PF04102.12 AAAP01003664.1_3 - 1.1e-19 70.8 0.9 1.2e-19 70.7 0.9 1.0 1 0 0 1 1 1 1 SlyX TolA_bind_tri PF16331.5 AAAP01003664.1_3 - 0.0041 17.2 1.1 0.0049 16.9 1.1 1.1 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF16 PF01519.16 AAAP01003664.1_3 - 0.0067 16.9 0.0 0.0078 16.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF16 HAP1_N PF04849.13 AAAP01003664.1_3 - 0.023 13.9 0.1 0.025 13.8 0.1 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 AAAP01003664.1_3 - 0.092 12.8 0.5 0.46 10.5 0.1 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 AAAP01003664.1_3 - 0.15 12.7 0.0 0.17 12.5 0.0 1.0 1 0 0 1 1 1 0 Initiation control protein YabA Nup88 PF10168.9 AAAP01003664.1_3 - 0.17 9.7 0.0 0.17 9.6 0.0 1.0 1 0 0 1 1 1 0 Nuclear pore component Unstab_antitox PF09720.10 AAAP01003664.1_3 - 0.21 11.7 4.2 0.24 11.5 0.5 2.3 1 1 0 2 2 2 0 Putative addiction module component HD_5 PF13487.6 AAAP01003664.1_4 - 1.4e-12 47.6 0.0 5.2e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003664.1_4 - 1.4e-10 41.5 0.2 2.3e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 HD domain DUF4616 PF15394.6 AAAP01003664.1_4 - 0.18 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Autotransporter PF03797.19 AAAP01003665.1_1 - 3.6e-05 23.5 3.6 3.6e-05 23.5 3.6 2.1 2 0 0 2 2 2 1 Autotransporter beta-domain SMC_N PF02463.19 AAAP01003665.1_2 - 8.9e-16 58.0 0.0 1.5e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003665.1_2 - 5.5e-09 36.8 0.0 2e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01003665.1_2 - 4.1e-07 30.1 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003665.1_2 - 0.0017 18.0 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01003665.1_2 - 0.002 18.4 0.1 0.036 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.6 AAAP01003665.1_2 - 0.02 13.5 1.2 0.03 13.0 1.2 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003665.1_2 - 0.036 14.0 0.1 0.098 12.6 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase NTPase_P4 PF11602.8 AAAP01003665.1_2 - 0.058 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF2813 PF11398.8 AAAP01003665.1_2 - 0.11 11.7 0.2 0.23 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) YfiO PF13525.6 AAAP01003665.1_3 - 1.1e-22 80.8 0.7 2.9e-22 79.4 0.4 1.7 1 1 1 2 2 2 1 Outer membrane lipoprotein TPR_6 PF13174.6 AAAP01003665.1_3 - 6.3e-06 26.5 1.1 0.035 14.7 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003665.1_3 - 0.015 15.8 0.7 0.059 13.9 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_18 PF13512.6 AAAP01003665.1_3 - 0.1 12.7 0.1 0.79 9.8 0.0 2.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003665.1_3 - 2.4 9.2 5.4 13 6.9 2.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4198 PF10670.9 AAAP01003666.1_1 - 6.9e-06 26.6 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) Big_1 PF02369.16 AAAP01003666.1_1 - 0.00044 20.2 0.4 0.0014 18.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 AAAP01003666.1_1 - 0.002 18.3 0.0 0.0062 16.8 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain bMG3 PF11974.8 AAAP01003666.1_1 - 0.037 14.0 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Milton PF12448.8 AAAP01003666.1_1 - 0.19 11.8 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Kinesin associated protein TonB_dep_Rec PF00593.24 AAAP01003666.1_2 - 1.1e-16 61.8 8.8 1.3e-16 61.5 8.8 1.0 1 0 0 1 1 1 1 TonB dependent receptor DUF4309 PF14172.6 AAAP01003666.1_2 - 0.025 14.6 0.3 0.032 14.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) DUF4085 PF13315.6 AAAP01003666.1_2 - 0.068 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Plug PF07715.15 AAAP01003666.1_3 - 7.1e-24 84.4 4.4 1.6e-23 83.4 4.4 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AAAP01003666.1_3 - 1.5e-13 51.5 33.3 7.5e-12 45.9 33.3 2.1 1 1 0 1 1 1 1 TonB dependent receptor DUF2946 PF11162.8 AAAP01003666.1_4 - 5.6e-05 23.8 5.1 7.5e-05 23.4 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Flg_bb_rod PF00460.20 AAAP01003667.1_1 - 7.6e-07 28.9 0.1 1.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAAP01003667.1_1 - 0.00034 20.7 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal DDE_Tnp_1_6 PF13751.6 AAAP01003667.1_3 - 2.8e-27 95.4 1.1 6.9e-27 94.1 1.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AAAP01003667.1_3 - 1.4e-16 60.3 0.0 2.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AAAP01003667.1_3 - 2.8e-08 33.7 0.0 9.2e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AAAP01003667.1_3 - 0.076 13.4 1.4 0.25 11.8 0.2 2.4 2 1 1 3 3 3 0 Transposase DDE domain Pyr_redox_2 PF07992.14 AAAP01003667.1_4 - 4.8e-33 114.7 0.0 7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAAP01003667.1_4 - 1e-23 83.7 0.0 2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAAP01003667.1_4 - 9.8e-15 54.9 0.0 1.8e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003667.1_4 - 1.9e-06 27.3 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003667.1_4 - 0.0017 18.0 0.1 0.0017 18.0 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAAP01003667.1_4 - 0.016 15.6 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 AAAP01003667.1_4 - 0.056 12.6 0.1 1 8.4 0.0 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AAAP01003667.1_4 - 0.081 11.6 0.1 0.24 10.1 0.0 1.7 1 1 1 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 AAAP01003667.1_4 - 0.15 12.0 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MerR-DNA-bind PF09278.11 AAAP01003667.1_5 - 1.6e-17 63.7 0.5 8e-17 61.5 0.5 1.8 2 0 0 2 2 2 1 MerR, DNA binding MerR_1 PF13411.6 AAAP01003667.1_5 - 4.7e-17 61.8 0.0 7.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003667.1_5 - 1.2e-14 53.7 0.1 2.7e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MarR_2 PF12802.7 AAAP01003667.1_5 - 0.0061 16.4 0.2 1.5 8.8 0.1 2.5 2 0 0 2 2 2 2 MarR family MCPsignal PF00015.21 AAAP01003668.1_1 - 4.9e-29 101.3 26.7 4.9e-29 101.3 26.7 3.9 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003668.1_1 - 1.8e-09 37.8 1.6 1.7e-07 31.5 0.0 4.3 3 1 1 4 4 4 1 HAMP domain DUF2746 PF10874.8 AAAP01003668.1_1 - 0.016 15.6 0.3 0.12 12.8 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) CorA PF01544.18 AAAP01003668.1_1 - 0.02 14.2 10.0 0.061 12.6 1.1 3.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.9 AAAP01003668.1_1 - 0.031 14.3 0.0 0.031 14.3 0.0 3.2 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 AAAP01003668.1_1 - 0.055 13.5 15.8 0.46 10.5 1.4 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Goodbye PF17109.5 AAAP01003668.1_1 - 0.21 12.1 10.9 0.59 10.6 0.8 3.1 2 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF948 PF06103.11 AAAP01003668.1_1 - 0.35 11.2 29.1 4.1 7.7 2.0 5.3 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF948) ECM11 PF15463.6 AAAP01003668.1_1 - 0.78 10.3 4.0 32 5.1 0.1 2.8 2 0 0 2 2 2 0 Extracellular mutant protein 11 Vps53_N PF04100.12 AAAP01003668.1_1 - 1.3 7.9 13.6 1.1 8.1 5.4 2.7 1 1 2 3 3 3 0 Vps53-like, N-terminal Sec34 PF04136.15 AAAP01003668.1_1 - 2.4 8.0 5.2 11 5.9 0.1 3.3 2 1 1 3 3 3 0 Sec34-like family Laminin_I PF06008.14 AAAP01003668.1_1 - 2.5 7.7 35.5 0.41 10.3 9.5 4.8 1 1 4 5 5 5 0 Laminin Domain I TMPIT PF07851.13 AAAP01003668.1_1 - 5 6.3 7.4 5.6 6.1 0.3 3.0 1 1 1 3 3 3 0 TMPIT-like protein Lin-8 PF03353.15 AAAP01003668.1_1 - 9.1 5.7 9.9 1.7 8.2 3.2 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist EpmC PF04315.12 AAAP01003668.1_2 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P hydroxylase Peptidase_M50 PF02163.22 AAAP01003668.1_2 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M50 ApbA PF02558.16 AAAP01003668.1_3 - 1.1e-34 119.3 0.0 1.4e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 AAAP01003668.1_3 - 1.7e-23 83.2 0.0 2.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 AAAP01003668.1_3 - 2.3e-05 24.9 0.1 0.00024 21.6 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ABC_tran PF00005.27 AAAP01003668.1_4 - 3.3e-45 154.0 0.0 4.5e-22 79.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AAAP01003668.1_4 - 8.3e-27 93.0 9.3 9.1e-26 89.7 5.8 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAAP01003668.1_4 - 4.9e-14 52.8 0.5 0.01 15.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003668.1_4 - 5.2e-09 35.9 0.2 0.0016 17.9 0.0 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003668.1_4 - 4.3e-06 27.4 5.9 0.0074 16.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AAAP01003668.1_4 - 1.6e-05 24.6 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003668.1_4 - 1.6e-05 24.9 0.3 0.18 11.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003668.1_4 - 2.7e-05 24.2 0.0 0.019 15.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AAAP01003668.1_4 - 5.4e-05 23.6 0.2 0.16 12.4 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 AAAP01003668.1_4 - 0.00011 22.6 1.0 0.45 10.9 0.0 3.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003668.1_4 - 0.00026 21.3 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AAAP01003668.1_4 - 0.0003 20.6 0.7 0.31 10.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 AAAP01003668.1_4 - 0.00081 19.9 1.7 2 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 AAAP01003668.1_4 - 0.00089 19.0 0.1 0.74 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AAAP01003668.1_4 - 0.0014 18.2 0.2 0.28 10.7 0.0 2.7 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 AAAP01003668.1_4 - 0.0015 18.8 0.1 0.43 10.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 AAAP01003668.1_4 - 0.0024 17.6 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 AAAP01003668.1_4 - 0.0025 18.0 2.1 2.2 8.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.6 AAAP01003668.1_4 - 0.0051 15.5 1.1 1.3 7.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 AAAP01003668.1_4 - 0.0067 16.7 1.0 5.3 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Arf PF00025.21 AAAP01003668.1_4 - 0.0089 15.5 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Ploopntkinase1 PF18748.1 AAAP01003668.1_4 - 0.014 14.9 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 NACHT PF05729.12 AAAP01003668.1_4 - 0.015 15.2 1.2 3.3 7.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 AAAP01003668.1_4 - 0.016 15.0 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 AAAP01003668.1_4 - 0.019 14.9 0.1 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 AAAP01003668.1_4 - 0.024 14.1 0.3 0.11 11.9 0.0 2.1 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 AAAP01003668.1_4 - 0.024 14.1 0.6 4.4 6.8 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region SbcCD_C PF13558.6 AAAP01003668.1_4 - 0.026 14.8 0.3 1.6 9.1 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 AAAP01003668.1_4 - 0.026 14.1 0.0 9.3 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AAAP01003668.1_4 - 0.031 14.0 0.1 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran_CTD PF16326.5 AAAP01003668.1_4 - 0.051 13.8 0.0 0.051 13.8 0.0 2.1 2 0 0 2 2 1 0 ABC transporter C-terminal domain AAA_8 PF12780.7 AAAP01003668.1_4 - 0.058 12.7 0.1 8.7 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_14 PF13173.6 AAAP01003668.1_4 - 0.061 13.4 0.0 11 6.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 AAAP01003668.1_4 - 0.067 12.4 0.1 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 AAAP01003668.1_4 - 0.076 12.0 0.2 6.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 AAAP01003668.1_4 - 0.098 12.2 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 AAAP01003668.1_4 - 0.15 12.0 0.7 9 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 AAAP01003668.1_4 - 0.17 11.4 0.3 8.7 5.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 AAAP01003668.1_4 - 0.19 9.2 9.6 0.92 6.9 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) SRP54 PF00448.22 AAAP01003668.1_4 - 0.27 10.8 1.8 8.5 5.9 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AAAP01003668.1_4 - 0.38 10.0 6.1 3.7 6.8 0.1 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_15 PF13175.6 AAAP01003668.1_4 - 0.5 10.0 4.9 9.4 5.8 0.1 3.4 4 0 0 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.23 AAAP01003668.1_4 - 0.86 9.6 2.7 24 4.9 0.0 2.7 3 0 0 3 3 2 0 Dynamin family DLIC PF05783.11 AAAP01003668.1_4 - 5.6 5.7 5.2 4.7 5.9 0.0 2.4 3 0 0 3 3 2 0 Dynein light intermediate chain (DLIC) DUF4231 PF14015.6 AAAP01003669.1_1 - 0.2 12.1 4.4 0.48 10.9 0.1 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF4231) Lipase_GDSL_2 PF13472.6 AAAP01003669.1_2 - 3.6e-06 27.5 0.0 0.00011 22.6 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1574 PF07611.11 AAAP01003669.1_2 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Exostosin PF03016.15 AAAP01003669.1_3 - 7.5e-07 28.7 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Exostosin family ECH_1 PF00378.20 AAAP01003669.1_4 - 1.2e-39 136.1 0.0 1.4e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003669.1_4 - 3.9e-19 69.3 0.2 3.5e-16 59.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MCPsignal PF00015.21 AAAP01003669.1_5 - 4.3e-17 62.4 1.6 5.4e-17 62.1 1.6 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BATS PF06968.13 AAAP01003669.1_5 - 0.068 13.3 0.1 0.12 12.5 0.1 1.4 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain Sel1 PF08238.12 AAAP01003669.1_6 - 3.1e-48 161.1 16.0 2.7e-10 40.6 0.1 6.4 6 0 0 6 6 6 6 Sel1 repeat TPR_16 PF13432.6 AAAP01003669.1_6 - 0.065 13.9 18.1 0.96 10.2 0.7 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Antiterm PF03589.13 AAAP01003669.1_6 - 0.19 12.1 0.2 1.4e+02 2.9 0.0 3.5 3 1 1 4 4 4 0 Antitermination protein Glyco_trans_2_3 PF13632.6 AAAP01003670.1_3 - 4.9e-08 33.1 0.3 6.3e-08 32.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AAAP01003670.1_3 - 9.6e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003670.1_3 - 0.00018 21.5 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 AAAP01003670.1_3 - 0.048 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Radical_SAM PF04055.21 AAAP01003670.1_4 - 6.7e-18 65.6 0.1 4.7e-17 62.9 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003670.1_4 - 2.4e-14 53.4 0.2 1.2e-13 51.2 0.1 2.2 2 0 0 2 2 2 1 B12 binding domain Radical_SAM PF04055.21 AAAP01003670.1_5 - 2e-06 28.3 0.0 3.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Bac_surface_Ag PF01103.23 AAAP01003671.1_1 - 6.5e-68 229.6 6.3 8.1e-68 229.3 6.3 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 AAAP01003671.1_1 - 0.082 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat OmpH PF03938.14 AAAP01003671.1_2 - 1.1e-17 64.7 11.0 1.3e-17 64.4 11.0 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) SIP1 PF04938.12 AAAP01003671.1_2 - 0.014 15.2 0.3 0.015 15.0 0.3 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) SHE3 PF17078.5 AAAP01003671.1_2 - 0.026 14.3 0.4 0.034 13.8 0.4 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Matrilin_ccoil PF10393.9 AAAP01003671.1_2 - 0.43 10.5 3.2 1.8 8.5 0.1 2.9 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Hexapep PF00132.24 AAAP01003671.1_3 - 2.1e-34 116.0 33.7 4.6e-10 38.8 4.3 5.7 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 AAAP01003671.1_3 - 1.3e-18 66.5 0.7 2.3e-18 65.7 0.7 1.4 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 AAAP01003671.1_3 - 3.7e-14 52.2 34.9 4.9e-09 35.8 4.0 5.7 6 0 0 6 6 6 4 Hexapeptide repeat of succinyl-transferase FabA PF07977.13 AAAP01003671.1_4 - 2.2e-37 127.8 0.1 2.6e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 AAAP01003671.1_4 - 0.00022 21.5 0.0 0.00036 20.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 AAAP01003671.1_4 - 0.015 14.8 0.1 0.027 14.0 0.1 1.4 1 1 0 1 1 1 0 MaoC like domain Acetyltransf_11 PF13720.6 AAAP01003671.1_5 - 3.3e-25 88.4 0.0 5.2e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AAAP01003671.1_5 - 3.4e-24 83.6 11.6 9.9e-09 34.6 0.1 6.3 6 1 1 7 7 7 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003671.1_5 - 2.9e-07 30.1 9.0 0.0063 16.2 0.1 5.1 6 0 0 6 6 6 3 Hexapeptide repeat of succinyl-transferase DUF2407_C PF13373.6 AAAP01003671.1_5 - 0.12 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain LpxI_C PF06230.11 AAAP01003671.1_6 - 8.2e-46 155.1 0.1 1.1e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 LpxI C-terminal domain LpxI_N PF17930.1 AAAP01003671.1_6 - 1.3e-38 131.8 0.1 1.9e-38 131.3 0.1 1.2 1 0 0 1 1 1 1 LpxI N-terminal domain LytR_C PF13399.6 AAAP01003671.1_6 - 0.093 13.7 0.1 0.22 12.5 0.1 1.7 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator LpxB PF02684.15 AAAP01003671.1_7 - 2.3e-96 322.9 0.0 2.6e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase SBP_bac_5 PF00496.22 AAAP01003672.1_2 - 2.3e-06 26.8 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BAG PF02179.16 AAAP01003672.1_2 - 0.13 12.8 0.1 1.5 9.3 0.1 2.1 2 0 0 2 2 2 0 BAG domain BPD_transp_1 PF00528.22 AAAP01003672.1_3 - 1.2e-38 132.7 9.4 1.2e-38 132.7 9.4 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAAP01003672.1_4 - 5.5e-32 111.0 8.6 5.5e-32 111.0 8.6 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Usp PF00582.26 AAAP01003672.1_5 - 4.4e-06 27.2 0.1 4.8e-06 27.1 0.1 1.2 1 1 0 1 1 1 1 Universal stress protein family SPOR PF05036.13 AAAP01003672.1_6 - 1e-09 38.6 0.9 3.4e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Sporulation related domain SHOCT PF09851.9 AAAP01003672.1_6 - 0.0003 20.4 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Short C-terminal domain GvpG PF05120.12 AAAP01003672.1_6 - 0.041 13.9 0.1 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 Gas vesicle protein G DUF2390 PF09523.10 AAAP01003672.1_6 - 0.19 12.1 1.1 8.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) TMEM71 PF15121.6 AAAP01003673.1_1 - 0.18 11.5 0.0 0.67 9.6 0.0 1.9 1 1 1 2 2 2 0 TMEM71 protein family FemAB_like PF04339.12 AAAP01003673.1_2 - 1.7e-153 511.2 0.1 1.9e-153 511.0 0.1 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 AAAP01003673.1_2 - 7.9e-11 42.3 4.1 7.9e-11 42.3 4.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Muraidase PF11860.8 AAAP01003673.1_2 - 0.07 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 N-acetylmuramidase Tropomyosin_1 PF12718.7 AAAP01003673.1_3 - 0.0037 17.4 1.0 0.0037 17.4 1.0 2.1 3 0 0 3 3 3 1 Tropomyosin like PL48 PF15903.5 AAAP01003673.1_3 - 0.0089 15.0 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 Sm_like PF16243.5 AAAP01003673.1_3 - 0.019 15.1 0.0 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Sm_like domain DUF2207 PF09972.9 AAAP01003673.1_3 - 0.022 13.6 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dynamitin PF04912.14 AAAP01003673.1_3 - 0.15 11.4 3.0 0.37 10.1 3.0 1.8 1 1 0 1 1 1 0 Dynamitin ABC_tran_CTD PF16326.5 AAAP01003673.1_3 - 0.27 11.5 4.4 0.096 12.9 1.6 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4164 PF13747.6 AAAP01003673.1_3 - 1.8 8.9 10.0 0.81 10.0 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HI0933_like PF03486.14 AAAP01003673.1_4 - 7.7e-66 222.5 0.0 9.2e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAAP01003673.1_4 - 2.5e-09 36.8 3.0 1.8e-08 33.9 3.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003673.1_4 - 5.7e-08 32.9 0.1 1.2e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003673.1_4 - 4.8e-07 29.7 3.4 0.00025 20.7 0.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003673.1_4 - 6.9e-07 28.8 0.1 1.6e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003673.1_4 - 9.6e-07 29.3 0.1 0.00036 21.0 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003673.1_4 - 2e-06 27.3 0.6 0.035 13.3 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01003673.1_4 - 0.00014 21.2 0.2 0.0002 20.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AAAP01003673.1_4 - 0.00015 21.3 0.5 0.00015 21.2 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003673.1_4 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAAP01003673.1_4 - 0.0027 17.0 0.1 0.0049 16.2 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 AAAP01003673.1_4 - 0.005 15.9 1.5 0.0067 15.5 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 AAAP01003673.1_4 - 0.0082 15.3 0.7 0.0082 15.3 0.7 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 AAAP01003673.1_4 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 AAAP01003673.1_4 - 0.046 13.3 0.2 0.065 12.8 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAAP01003673.1_4 - 0.18 11.7 0.3 0.28 11.1 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.18 AAAP01003673.1_4 - 0.26 9.7 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor CitG PF01874.16 AAAP01003674.1_1 - 1.6e-45 155.9 1.3 1.9e-45 155.7 1.3 1.1 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase MdcG PF10620.9 AAAP01003674.1_2 - 4.6e-50 170.2 2.7 5.2e-50 170.0 2.7 1.0 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG MdcE PF06833.11 AAAP01003674.1_3 - 3.8e-68 229.4 0.4 4.3e-68 229.3 0.4 1.0 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Carboxyl_trans PF01039.22 AAAP01003674.1_3 - 0.0026 16.5 0.1 0.0033 16.1 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Sgf11 PF08209.11 AAAP01003674.1_3 - 0.031 13.8 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Carboxyl_trans PF01039.22 AAAP01003674.1_4 - 4e-20 71.9 0.1 5e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ACP PF06857.11 AAAP01003674.1_5 - 8.7e-24 83.6 0.0 9.8e-24 83.4 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) Mal_decarbox_Al PF16957.5 AAAP01003674.1_6 - 8.8e-78 262.0 0.0 1e-77 261.7 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter MCPsignal PF00015.21 AAAP01003675.1_1 - 3.1e-31 108.5 24.9 3.1e-31 108.5 24.9 3.0 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003675.1_1 - 6.4e-08 32.8 1.1 5.8e-07 29.8 0.0 3.2 3 1 0 3 3 3 1 HAMP domain DUF3450 PF11932.8 AAAP01003675.1_1 - 0.0048 16.2 4.7 0.0048 16.2 4.7 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 AAAP01003675.1_1 - 0.039 14.3 5.5 4 7.9 0.1 4.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 AAAP01003675.1_1 - 0.047 13.7 15.5 0.63 10.1 2.7 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 AAAP01003675.1_1 - 0.11 12.3 11.5 0.16 11.8 1.9 3.0 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Transcrip_act PF04949.13 AAAP01003675.1_1 - 0.17 11.7 3.4 5.3 6.9 0.4 3.2 1 1 2 3 3 3 0 Transcriptional activator DUF948 PF06103.11 AAAP01003675.1_1 - 1.2 9.4 28.8 4.5 7.6 2.1 5.8 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AAAP01003675.1_1 - 3.4 7.8 8.3 8.8 6.5 0.4 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 AAAP01003675.1_1 - 4.5 7.3 25.3 0.7 9.9 3.4 4.3 1 1 4 5 5 5 0 Laminin Domain II Nup54 PF13874.6 AAAP01003675.1_1 - 7.3 6.7 16.3 12 6.0 4.4 2.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 IFT57 PF10498.9 AAAP01003675.1_1 - 8.5 5.2 9.7 2.5 7.0 2.1 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MCPsignal PF00015.21 AAAP01003675.1_2 - 2.3e-30 105.7 48.9 1.1e-29 103.5 26.3 4.0 2 2 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003675.1_2 - 1.2e-08 35.2 0.2 1.2e-08 35.2 0.2 3.5 4 0 0 4 4 4 1 HAMP domain Laminin_I PF06008.14 AAAP01003675.1_2 - 0.00073 19.3 7.6 0.00073 19.3 7.6 3.5 2 1 3 5 5 5 1 Laminin Domain I PAS_9 PF13426.7 AAAP01003675.1_2 - 0.0011 19.2 0.0 0.0054 17.0 0.0 2.2 1 1 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003675.1_2 - 0.052 13.8 0.0 1.2 9.4 0.0 3.1 1 1 0 1 1 1 0 PAS fold DUF1664 PF07889.12 AAAP01003675.1_2 - 0.32 11.0 18.4 0.57 10.2 0.9 4.8 4 3 3 7 7 7 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAAP01003675.1_2 - 3.1 8.2 14.9 5.5 7.4 1.4 4.6 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 AAAP01003675.1_2 - 3.6 7.6 24.2 1.6 8.8 6.1 5.1 2 1 3 5 5 5 0 Laminin Domain II Fib_alpha PF08702.10 AAAP01003675.1_2 - 4 7.6 7.0 7.5 6.7 1.0 3.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 AAAP01003675.1_2 - 6.2 7.2 29.4 0.94 9.8 4.1 6.1 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF3829 PF12889.7 AAAP01003675.1_2 - 7.2 6.0 10.9 0.76 9.2 3.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) BLUF PF04940.12 AAAP01003675.1_3 - 4.4e-23 81.2 0.0 6.7e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Sensors of blue-light using FAD Phage_integrase PF00589.22 AAAP01003675.1_4 - 7.2e-23 81.2 0.3 8e-23 81.1 0.3 1.0 1 0 0 1 1 1 1 Phage integrase family FliMN_C PF01052.20 AAAP01003675.1_4 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term Phage_integr_3 PF16795.5 AAAP01003675.1_4 - 0.073 13.0 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 Archaeal phage integrase Response_reg PF00072.24 AAAP01003675.1_5 - 4.4e-23 81.6 0.2 4.9e-23 81.4 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain GFO_IDH_MocA PF01408.22 AAAP01003675.1_5 - 0.028 15.3 0.0 0.042 14.7 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold HD PF01966.22 AAAP01003675.1_6 - 8.5e-16 58.3 0.4 1.2e-15 57.8 0.4 1.2 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01003675.1_6 - 4.1e-10 39.8 0.0 9.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAAP01003675.1_6 - 0.00017 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 HDOD domain T3SS_basalb_I PF17001.5 AAAP01003676.1_4 - 0.0027 18.3 1.9 0.003 18.1 1.9 1.0 1 0 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI Phage_integrase PF00589.22 AAAP01003676.1_5 - 7.3e-25 87.7 0.3 8.4e-25 87.5 0.3 1.0 1 0 0 1 1 1 1 Phage integrase family FliMN_C PF01052.20 AAAP01003676.1_5 - 0.0033 17.4 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term Phage_integr_3 PF16795.5 AAAP01003676.1_5 - 0.022 14.7 0.1 0.17 11.8 0.1 2.1 1 1 0 1 1 1 0 Archaeal phage integrase PAS_3 PF08447.12 AAAP01003676.1_6 - 5.8e-20 71.4 0.9 1e-13 51.3 0.3 2.4 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAAP01003676.1_6 - 7.6e-20 71.5 0.2 1.4e-19 70.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAAP01003676.1_6 - 9.2e-18 64.4 0.1 6.4e-10 39.2 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAAP01003676.1_6 - 2.7e-15 56.6 0.0 1.9e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01003676.1_6 - 5.9e-15 55.2 0.0 3e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 AAAP01003676.1_6 - 2.7e-11 43.3 0.0 5.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003676.1_6 - 7.5e-06 25.8 0.0 0.00021 21.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_10 PF13596.6 AAAP01003676.1_6 - 0.023 15.3 0.0 3.9 8.1 0.0 2.8 3 0 0 3 3 3 0 PAS domain HATPase_c_5 PF14501.6 AAAP01003676.1_6 - 0.078 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 GHKL domain dCache_1 PF02743.18 AAAP01003676.1_6 - 0.17 11.7 0.0 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Cache domain ABC_membrane PF00664.23 AAAP01003677.1_2 - 3.4e-41 141.7 11.5 4.3e-41 141.4 11.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003677.1_2 - 3.4e-33 115.1 0.0 8.5e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Peptidase_C39 PF03412.15 AAAP01003677.1_2 - 1.6e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family SMC_N PF02463.19 AAAP01003677.1_2 - 8.9e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAAP01003677.1_2 - 0.018 15.3 0.1 0.077 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AAAP01003677.1_2 - 0.027 14.7 0.3 0.65 10.3 0.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 AAAP01003677.1_2 - 0.032 13.0 0.6 0.051 12.4 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 AAAP01003677.1_2 - 0.038 13.8 0.2 0.77 9.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003677.1_2 - 0.065 13.6 0.3 0.2 12.0 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain MoeA_C PF03454.15 AAAP01003677.1_2 - 0.15 12.3 0.2 3 8.1 0.0 2.6 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) Zeta_toxin PF06414.12 AAAP01003677.1_2 - 0.17 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 AAAP01003677.1_2 - 0.18 11.8 0.1 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain FCSD-flav_bind PF09242.11 AAAP01003677.1_2 - 0.22 11.9 0.0 0.95 9.9 0.0 2.0 2 0 0 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding HlyD_3 PF13437.6 AAAP01003677.1_3 - 1e-15 58.3 0.7 6e-11 43.0 0.1 2.9 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003677.1_3 - 3.8e-09 36.1 4.3 3.2e-06 26.5 1.2 2.5 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAAP01003677.1_3 - 9.7e-07 28.6 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003677.1_3 - 6e-06 26.0 0.9 2.9e-05 23.8 0.1 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like cNMP_binding PF00027.29 AAAP01003677.1_3 - 7.5e-05 22.7 0.0 0.00023 21.2 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Biotin_lipoyl PF00364.22 AAAP01003677.1_3 - 0.0021 17.9 0.1 0.0054 16.5 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme SLATT_4 PF18186.1 AAAP01003677.1_3 - 0.2 11.3 3.8 0.23 11.1 1.7 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 LMBR1 PF04791.16 AAAP01003677.1_3 - 1.1 8.0 4.6 1.7 7.4 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAS PF13851.6 AAAP01003677.1_3 - 4.2 6.7 13.4 6.4 6.1 13.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rrf2 PF02082.20 AAAP01003678.1_1 - 6.9e-17 61.6 0.1 1.1e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 AAAP01003678.1_1 - 0.024 14.3 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MarR_2 PF12802.7 AAAP01003678.1_1 - 0.044 13.7 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family Aminotran_5 PF00266.19 AAAP01003678.1_2 - 1.2e-14 54.0 0.0 1.4e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DUF5615 PF18480.1 AAAP01003678.1_2 - 0.021 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Aminotran_5 PF00266.19 AAAP01003678.1_3 - 1.5e-39 136.0 0.1 2e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 AAAP01003678.1_3 - 0.067 11.9 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 AAAP01003678.1_4 - 7.3e-87 291.7 0.0 8.9e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01003678.1_4 - 1.2e-08 34.7 0.1 1.2e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAAP01003678.1_4 - 2.4e-07 30.4 1.3 3.7e-07 29.8 1.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 AAAP01003678.1_4 - 0.038 12.7 0.1 0.054 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain B12-binding PF02310.19 AAAP01003678.1_4 - 0.13 12.3 0.9 27 4.8 0.0 3.0 4 0 0 4 4 4 0 B12 binding domain NifU_N PF01592.16 AAAP01003678.1_5 - 2.5e-57 192.5 0.3 2.8e-57 192.4 0.3 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Fe-S_biosyn PF01521.20 AAAP01003678.1_6 - 2.3e-22 79.3 0.0 2.5e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HSCB_C PF07743.13 AAAP01003678.1_7 - 4e-14 52.9 8.3 6.1e-14 52.3 5.0 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 AAAP01003678.1_7 - 5.3e-08 32.9 0.1 9.3e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.6 AAAP01003678.1_7 - 0.0019 17.5 1.0 0.0019 17.5 1.0 1.8 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 AAAP01003678.1_7 - 0.011 15.7 0.8 0.034 14.2 0.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon Cytochrom_C552 PF02335.15 AAAP01003678.1_7 - 0.026 13.4 2.8 1 8.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c552 HscB_4_cys PF18256.1 AAAP01003678.1_7 - 0.088 12.6 4.5 0.29 11.0 4.5 1.9 1 1 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif HSP70 PF00012.20 AAAP01003678.1_8 - 1.2e-134 449.8 0.1 1.4e-134 449.5 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AAAP01003678.1_8 - 4.1e-21 75.2 3.0 2.7e-17 62.6 0.6 2.1 1 1 0 2 2 2 2 MreB/Mbl protein Raco_middle PF17651.1 AAAP01003678.1_8 - 0.028 14.1 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 RACo middle region FtsA PF14450.6 AAAP01003678.1_8 - 0.037 14.4 2.3 1.6 9.2 0.1 2.9 3 0 0 3 3 3 0 Cell division protein FtsA HTH_Tnp_1 PF01527.20 AAAP01003679.1_1 - 5.8e-19 68.2 0.0 7.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01003679.1_1 - 0.00091 19.0 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003679.1_1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003679.1_1 - 0.021 14.9 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Cep57_MT_bd PF06657.13 AAAP01003679.1_1 - 0.036 14.5 0.3 0.16 12.4 0.3 1.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HTH_Tnp_1_2 PF13022.6 AAAP01003679.1_1 - 0.055 13.6 0.1 0.074 13.2 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase PAS PF00989.25 AAAP01003679.1_5 - 0.086 12.9 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 PAS fold Hemerythrin PF01814.23 AAAP01003679.1_6 - 1.5e-10 41.8 1.7 1.8e-10 41.6 1.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2384 PF09722.10 AAAP01003679.1_7 - 5.4e-08 32.8 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Auto_anti-p27 PF06677.12 AAAP01003679.1_8 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HTH_3 PF01381.22 AAAP01003679.1_9 - 2.5e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003679.1_9 - 9.6e-06 25.9 0.1 1.5e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003679.1_9 - 0.00047 20.1 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Peptidase_M78 PF06114.13 AAAP01003679.1_9 - 0.054 13.4 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 IrrE N-terminal-like domain YdaS_antitoxin PF15943.5 AAAP01003679.1_9 - 0.11 12.4 0.1 0.38 10.6 0.0 1.9 2 1 1 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Abhydrolase_6 PF12697.7 AAAP01003680.1_1 - 7.4e-10 39.8 5.8 8.6e-10 39.6 5.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01003680.1_1 - 8.4e-09 35.0 1.9 9.2e-09 34.9 1.9 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003680.1_1 - 7.1e-07 29.1 1.4 8e-07 29.0 1.4 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 AAAP01003680.1_1 - 0.064 12.8 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FliMN_C PF01052.20 AAAP01003680.1_3 - 8.4e-25 86.6 1.4 9.9e-25 86.3 1.4 1.1 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term TAL_FSA PF00923.19 AAAP01003680.1_4 - 6.8e-60 202.8 0.2 1.6e-58 198.3 0.2 2.2 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase ALAD PF00490.21 AAAP01003680.1_4 - 0.1 11.7 0.2 0.43 9.7 0.1 1.9 1 1 1 2 2 2 0 Delta-aminolevulinic acid dehydratase PfkB PF00294.24 AAAP01003680.1_5 - 8e-38 130.4 0.1 1.4e-19 70.6 0.3 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase LEM PF03020.15 AAAP01003680.1_5 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 LEM domain Phos_pyr_kin PF08543.12 AAAP01003680.1_5 - 0.0031 16.9 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase V_ATPase_prox PF18274.1 AAAP01003680.1_5 - 0.05 13.6 0.3 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe MFS_3 PF05977.13 AAAP01003680.1_6 - 1.6e-41 142.4 15.7 1.8e-41 142.1 15.7 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAAP01003680.1_6 - 6e-18 64.9 26.6 6.9e-18 64.7 26.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CheB_methylest PF01339.17 AAAP01003681.1_1 - 4.3e-60 202.3 0.0 6.2e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 CheB methylesterase CheR_N PF03705.15 AAAP01003681.1_1 - 1.4e-14 53.5 0.2 2.4e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain rve PF00665.26 AAAP01003681.1_2 - 4.8e-07 30.0 0.0 5.3e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 AAAP01003681.1_3 - 1.2e-11 44.0 1.2 2.2e-08 33.6 0.1 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.6 AAAP01003681.1_3 - 3.7e-11 43.5 0.6 9.5e-11 42.2 0.6 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003681.1_3 - 1.7e-10 40.7 0.6 1.7e-08 34.3 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003681.1_3 - 2.2e-05 24.5 3.1 0.0037 17.3 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAAP01003681.1_3 - 6e-05 23.5 1.5 0.00016 22.1 0.1 2.2 1 1 1 2 2 2 1 leucine-zipper of insertion element IS481 HTH_31 PF13560.6 AAAP01003681.1_3 - 0.06 13.7 1.4 0.12 12.8 0.3 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01003681.1_3 - 0.15 11.9 0.2 4.5 7.1 0.2 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Nit_Regul_Hom PF10126.9 AAAP01003681.1_3 - 0.18 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII HTH_6 PF01418.17 AAAP01003681.1_3 - 0.2 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Response_reg PF00072.24 AAAP01003681.1_4 - 1e-06 28.9 0.0 1.1e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AAAP01003681.1_5 - 3.2e-44 149.7 1.2 2.1e-25 89.0 0.7 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003681.1_5 - 2.7e-26 92.3 0.2 5.2e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003681.1_5 - 1.3e-19 69.9 0.8 5.4e-19 68.0 0.8 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAAP01003681.1_5 - 4.2e-11 43.0 2.7 4.2e-11 43.0 2.7 2.9 2 0 0 2 2 2 1 Hpt domain PAS_9 PF13426.7 AAAP01003681.1_5 - 8.7e-09 35.6 0.0 2.4e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 AAAP01003681.1_5 - 2.7e-05 24.3 0.0 0.38 10.9 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AAAP01003681.1_5 - 3.6e-05 23.7 0.0 8.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003681.1_5 - 3.9e-05 23.9 0.1 0.00021 21.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003681.1_5 - 9.6e-05 22.3 0.0 0.00044 20.2 0.0 2.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AAAP01003681.1_5 - 0.057 13.7 0.2 0.42 10.9 0.2 2.5 1 1 0 1 1 1 0 PAS fold SSF PF00474.17 AAAP01003682.1_1 - 2.8e-31 108.8 3.0 3.3e-31 108.6 3.0 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 AAAP01003682.1_1 - 0.0064 17.0 0.1 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2818) Spore_permease PF03845.13 AAAP01003682.1_1 - 0.016 14.1 0.3 0.016 14.1 0.3 1.5 2 0 0 2 2 2 0 Spore germination protein MgtC PF02308.16 AAAP01003682.1_1 - 0.13 12.6 4.8 0.26 11.7 4.8 1.6 1 1 0 1 1 1 0 MgtC family SSF PF00474.17 AAAP01003682.1_2 - 3.2e-45 154.7 21.8 3.2e-45 154.7 21.8 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family EIAV_GP90 PF00971.18 AAAP01003682.1_2 - 0.25 10.0 0.3 0.36 9.4 0.3 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 DUF485 PF04341.12 AAAP01003682.1_3 - 1.7e-33 114.4 0.4 1.9e-33 114.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 MASE3 PF17159.4 AAAP01003682.1_3 - 0.0026 17.4 0.3 0.0029 17.2 0.3 1.0 1 0 0 1 1 1 1 Membrane-associated sensor domain E1-E2_ATPase PF00122.20 AAAP01003682.1_3 - 0.05 13.1 1.0 0.061 12.8 1.0 1.1 1 0 0 1 1 1 0 E1-E2 ATPase DUF294 PF03445.13 AAAP01003682.1_4 - 3.8e-37 127.2 0.0 6.4e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 AAAP01003682.1_4 - 2.4e-29 102.0 1.9 5.8e-29 100.7 1.0 1.9 2 0 0 2 2 2 1 Putative nucleotidyltransferase substrate binding domain CBS PF00571.28 AAAP01003682.1_4 - 1.2e-21 76.9 4.6 1.2e-10 41.7 0.3 2.9 3 0 0 3 3 3 2 CBS domain RNase_T PF00929.24 AAAP01003682.1_5 - 1.5e-34 119.9 0.0 2.4e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 AAAP01003682.1_5 - 2.7e-06 27.2 0.0 0.00042 20.1 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease PAS PF00989.25 AAAP01003682.1_5 - 0.00014 21.9 0.1 0.00047 20.1 0.1 2.0 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003682.1_5 - 0.0041 17.1 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 AAAP01003682.1_5 - 0.027 14.6 0.2 0.098 12.8 0.1 2.1 2 1 0 2 2 2 0 PAS fold PAS_4 PF08448.10 AAAP01003682.1_5 - 0.07 13.4 1.7 1.2 9.4 0.1 3.2 2 1 0 2 2 2 0 PAS fold ACR_tran PF00873.19 AAAP01003683.1_1 - 1.1e-193 645.7 8.2 1.3e-193 645.5 8.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003683.1_1 - 4.3e-06 25.9 13.8 8.1e-06 25.0 13.8 1.4 1 0 0 1 1 1 1 MMPL family ZT_dimer PF16916.5 AAAP01003683.1_1 - 0.014 15.5 0.2 0.097 12.8 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter Patched PF02460.18 AAAP01003683.1_1 - 3 5.8 13.8 4.6 5.2 13.8 1.1 1 0 0 1 1 1 0 Patched family MgtE PF01769.16 AAAP01003683.1_1 - 3.6 8.0 14.6 2.2 8.7 2.7 2.9 3 0 0 3 3 3 0 Divalent cation transporter HlyD_D23 PF16576.5 AAAP01003683.1_2 - 3e-53 180.2 1.2 3e-53 180.2 1.2 3.1 3 1 0 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003683.1_2 - 2.7e-21 76.3 1.1 3.6e-18 66.2 0.0 3.2 3 0 0 3 3 3 2 HlyD family secretion protein HlyD PF00529.20 AAAP01003683.1_2 - 4.6e-08 32.8 1.1 0.00072 19.4 0.0 2.8 2 1 0 2 2 2 2 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAAP01003683.1_2 - 0.00044 20.0 0.1 0.85 9.5 0.0 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_2 PF12700.7 AAAP01003683.1_2 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01003683.1_2 - 0.85 9.5 5.5 6 6.8 0.0 3.0 3 0 0 3 3 3 0 Biotin-lipoyl like OEP PF02321.18 AAAP01003683.1_3 - 1.6e-45 155.3 9.6 7.7e-25 87.8 0.5 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Hexapep PF00132.24 AAAP01003684.1_1 - 8e-12 44.4 5.8 8.4e-07 28.5 0.6 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 AAAP01003684.1_1 - 3.8e-05 24.0 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 AAAP01003684.1_1 - 0.0013 18.5 11.8 0.017 14.9 3.2 2.7 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Hydrolase_4 PF12146.8 AAAP01003684.1_2 - 4.8e-11 42.4 0.3 4e-08 32.8 0.1 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 AAAP01003684.1_2 - 4.3e-09 36.2 0.3 0.00017 21.1 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AAAP01003684.1_2 - 8e-09 35.5 0.0 1.7e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 AAAP01003684.1_2 - 1.4e-07 32.4 0.4 8.3e-05 23.3 0.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003684.1_2 - 2.2e-07 30.8 0.3 4.3e-05 23.3 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 AAAP01003684.1_2 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 AAAP01003684.1_2 - 0.0082 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 AAAP01003684.1_2 - 0.03 14.0 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 AAAP01003684.1_2 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 AAAP01003684.1_2 - 0.2 11.6 0.0 10 6.0 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal AnmK PF03702.14 AAAP01003684.1_3 - 5.5e-77 259.3 0.0 7.1e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase tRNA-synt_1b PF00579.25 AAAP01003684.1_4 - 2.6e-71 240.4 0.0 3.2e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AAAP01003684.1_4 - 0.032 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 S4 domain Frataxin_Cyay PF01491.16 AAAP01003684.1_5 - 2.5e-26 91.8 0.0 2.7e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Ribosomal_L31 PF01197.18 AAAP01003684.1_6 - 7.8e-26 90.1 0.0 8.8e-26 89.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 Pyr_redox_2 PF07992.14 AAAP01003685.1_1 - 6e-24 84.8 0.1 7.7e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003685.1_1 - 2.3e-09 36.9 0.0 1.3e-05 24.6 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003685.1_1 - 5.7e-05 22.0 0.0 0.16 10.6 0.1 3.2 2 1 1 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 AAAP01003685.1_1 - 9.9e-05 22.4 1.1 0.011 15.7 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 AAAP01003685.1_1 - 0.00018 22.0 0.4 0.072 13.7 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003685.1_1 - 0.00088 19.0 6.5 0.0043 16.7 0.0 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003685.1_1 - 0.004 17.3 3.2 0.094 13.0 0.3 3.0 3 1 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01003685.1_1 - 0.0067 15.6 9.0 5.2 6.0 0.0 4.1 2 2 2 4 4 4 2 FAD binding domain Lycopene_cycl PF05834.12 AAAP01003685.1_1 - 0.0085 15.2 0.2 5.1 6.0 0.1 2.7 2 1 0 3 3 3 2 Lycopene cyclase protein NAD_binding_7 PF13241.6 AAAP01003685.1_1 - 0.014 15.8 0.1 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 AAAP01003685.1_1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 AAAP01003685.1_1 - 0.061 12.6 0.4 8.7 5.5 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NIL PF09383.10 AAAP01003685.1_1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NIL domain CooT PF10133.9 AAAP01003685.1_1 - 0.092 13.0 0.0 9.2 6.6 0.0 2.2 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT AlaDh_PNT_C PF01262.21 AAAP01003685.1_1 - 0.11 11.7 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AAAP01003685.1_1 - 0.13 11.4 0.2 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Thi4 family CusF_Ec PF11604.8 AAAP01003685.1_2 - 2.6e-23 81.7 0.0 4.5e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF DUF4421 PF14391.6 AAAP01003685.1_2 - 0.099 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) DUF411 PF04214.13 AAAP01003685.1_3 - 3.6e-30 103.7 0.5 4.9e-30 103.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF MFS_1 PF07690.16 AAAP01003685.1_5 - 2.3e-06 26.8 12.0 3.4e-06 26.2 12.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 AAAP01003685.1_5 - 0.0034 15.9 0.9 0.0038 15.7 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 AAAP01003685.1_5 - 0.01 14.7 4.1 0.011 14.6 4.1 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 AAAP01003685.1_6 - 0.00095 18.2 12.9 0.0011 18.0 12.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.21 AAAP01003685.1_6 - 0.52 10.0 10.3 0.075 12.8 6.6 1.4 2 0 0 2 2 2 0 Cation efflux family Cation_efflux PF01545.21 AAAP01003685.1_7 - 2.2e-06 27.5 1.7 2.4e-06 27.4 1.7 1.0 1 0 0 1 1 1 1 Cation efflux family MerR-DNA-bind PF09278.11 AAAP01003685.1_8 - 5.1e-22 78.2 2.7 8.1e-22 77.5 2.7 1.3 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAAP01003685.1_8 - 4.5e-18 65.1 0.2 7.3e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003685.1_8 - 4e-13 48.9 3.1 8e-13 47.9 3.1 1.5 1 0 0 1 1 1 1 MerR family regulatory protein DUF29 PF01724.16 AAAP01003685.1_8 - 0.19 12.0 0.0 0.25 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 MerR-DNA-bind PF09278.11 AAAP01003685.1_9 - 3.1e-21 75.7 5.8 4.8e-21 75.0 5.8 1.3 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAAP01003685.1_9 - 2.4e-17 62.8 0.2 4.9e-17 61.8 0.1 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003685.1_9 - 2.3e-13 49.7 0.8 4.2e-13 48.8 0.8 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_23 PF13384.6 AAAP01003685.1_9 - 0.0073 16.1 0.5 1.5 8.8 0.1 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 AAAP01003685.1_9 - 0.011 15.8 0.3 0.11 12.5 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix CHASE3 PF05227.13 AAAP01003685.1_9 - 0.016 15.1 0.9 0.024 14.6 0.9 1.2 1 0 0 1 1 1 0 CHASE3 domain FAD_binding_3 PF01494.19 AAAP01003685.1_9 - 0.026 13.8 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain AbiEi_4 PF13338.6 AAAP01003685.1_9 - 0.039 14.1 0.1 0.092 12.9 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Osmo_CC PF08946.10 AAAP01003685.1_9 - 0.064 13.5 1.2 0.16 12.2 0.6 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil MFS_1 PF07690.16 AAAP01003685.1_10 - 2.6e-23 82.5 13.7 2.9e-23 82.4 13.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01003685.1_10 - 1e-07 31.6 5.7 1.2e-07 31.4 5.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AAAP01003685.1_10 - 2.2e-07 30.1 2.9 3.2e-07 29.6 2.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 AAAP01003685.1_10 - 0.038 12.3 1.0 0.041 12.2 1.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BTP PF05232.12 AAAP01003685.1_10 - 0.069 13.2 0.3 0.069 13.2 0.3 2.3 1 1 1 2 2 2 0 Chlorhexidine efflux transporter LysR_substrate PF03466.20 AAAP01003686.1_1 - 4.4e-26 91.6 3.8 6.1e-26 91.1 3.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003686.1_1 - 1.4e-16 60.2 0.2 2.9e-16 59.1 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAAP01003686.1_1 - 0.00015 21.5 0.1 0.00033 20.4 0.1 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Fe_dep_repress PF01325.19 AAAP01003686.1_1 - 0.042 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 AAAP01003686.1_1 - 0.42 10.6 3.9 1 9.3 0.5 2.9 3 0 0 3 3 3 0 MarR family Sarcolipin PF05366.11 AAAP01003686.1_2 - 3.7 7.3 7.5 0.61 9.8 2.4 2.0 2 0 0 2 2 2 0 Sarcolipin K_oxygenase PF13434.6 AAAP01003686.1_3 - 2.4e-13 49.9 0.0 1.2e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 AAAP01003686.1_3 - 2.2e-11 43.6 0.0 8.3e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01003686.1_3 - 4.7e-11 42.9 0.1 3.3e-10 40.2 0.2 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAAP01003686.1_3 - 0.00012 21.5 0.0 0.0014 17.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003686.1_3 - 0.0058 15.4 0.0 2.1 6.9 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 AAAP01003686.1_3 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 AAAP01003686.1_3 - 0.0091 16.2 0.1 0.028 14.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003686.1_3 - 0.028 14.0 6.6 7.3 6.1 6.6 3.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003686.1_3 - 0.044 12.9 4.5 0.24 10.4 1.3 2.3 1 1 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 AAAP01003686.1_3 - 0.13 11.5 0.2 0.33 10.1 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain Questin_oxidase PF14027.6 AAAP01003686.1_4 - 1.7e-28 100.2 0.1 2.1e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like Amidohydro_1 PF01979.20 AAAP01003686.1_5 - 7.2e-36 124.2 0.1 9.7e-36 123.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003686.1_5 - 2.9e-10 40.2 3.3 2.9e-10 40.2 3.3 1.9 2 0 0 2 2 2 1 Amidohydrolase family FeS PF04060.13 AAAP01003686.1_6 - 0.3 10.8 2.0 6.4 6.5 0.3 2.1 1 1 1 2 2 2 0 Putative Fe-S cluster NADHdh PF00146.21 AAAP01003687.1_1 - 1.9e-64 217.9 15.1 2.2e-64 217.6 15.1 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.27 AAAP01003687.1_2 - 1.2e-14 53.4 15.8 6.5e-09 35.2 3.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003687.1_2 - 5.3e-14 52.5 9.2 7.6e-14 52.0 9.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003687.1_2 - 2e-11 44.6 5.0 1.3e-05 26.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003687.1_2 - 1.1e-10 41.4 3.1 9.6e-05 22.4 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003687.1_2 - 1.7e-09 37.7 9.0 2.7e-09 37.0 9.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003687.1_2 - 5.2e-09 36.4 18.5 3.8e-06 27.3 10.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003687.1_2 - 1.5e-08 34.6 22.1 1.3e-05 25.2 13.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003687.1_2 - 3.5e-07 29.9 11.6 0.0014 18.6 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003687.1_2 - 3.6e-07 30.0 17.5 0.00025 21.0 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003687.1_2 - 3.2e-06 27.2 11.1 0.00037 20.8 2.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003687.1_2 - 0.00013 22.5 12.4 0.0086 16.6 12.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003687.1_2 - 0.004 18.0 16.5 0.0096 16.8 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 AAAP01003687.1_2 - 0.0049 17.4 14.6 0.25 11.9 3.6 2.5 2 1 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 AAAP01003687.1_2 - 0.0096 16.1 4.6 0.68 10.2 0.4 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 AAAP01003687.1_2 - 0.011 15.9 8.1 1.7 8.9 8.1 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003687.1_2 - 0.44 11.4 11.5 1.8 9.4 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 AAAP01003687.1_2 - 0.47 10.6 5.8 1.1 9.4 0.9 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Oxidored_q3 PF00499.20 AAAP01003687.1_3 - 5.9e-06 26.1 0.3 5.9e-06 26.1 0.3 1.6 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Oxidored_q3 PF00499.20 AAAP01003687.1_4 - 4.5e-26 91.3 18.3 5.1e-26 91.1 18.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4006 PF13179.6 AAAP01003687.1_4 - 0.032 14.1 0.2 0.032 14.1 0.2 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Oxidored_q2 PF00420.24 AAAP01003687.1_5 - 2.8e-24 84.8 12.2 3.4e-24 84.5 12.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Gram_pos_anchor PF00746.21 AAAP01003687.1_5 - 1.7 8.7 5.3 4.3 7.4 0.2 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PEP-CTERM PF07589.11 AAAP01003687.1_5 - 2.7 8.2 7.7 0.98 9.6 0.5 3.0 3 0 0 3 3 3 0 PEP-CTERM motif Proton_antipo_M PF00361.20 AAAP01003687.1_6 - 1.8e-93 312.9 18.7 3.8e-93 311.9 18.7 1.6 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAAP01003687.1_6 - 3.3e-22 78.3 8.4 7e-22 77.3 3.2 3.2 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 AAAP01003687.1_6 - 9.2e-09 35.1 10.2 0.0012 18.5 0.0 4.5 4 0 0 4 4 4 2 NADH dehydrogenase subunit 5 C-terminus Proton_antipo_C PF01010.19 AAAP01003687.1_6 - 5.9e-05 22.8 0.6 0.00038 20.2 0.6 2.1 1 1 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus FATC PF02260.20 AAAP01003687.1_6 - 0.043 13.6 0.1 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 FATC domain Proton_antipo_M PF00361.20 AAAP01003687.1_7 - 1.3e-90 303.6 28.6 1.3e-90 303.6 28.6 2.0 1 1 1 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 AAAP01003687.1_7 - 4.2e-06 26.8 3.3 4.2e-06 26.8 3.3 3.7 3 1 0 3 3 3 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus GPR_Gpa2_C PF11970.8 AAAP01003687.1_7 - 1.9 8.6 5.8 4.6 7.4 1.1 3.3 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DDE_Tnp_Tn3 PF01526.17 AAAP01003688.1_1 - 6.8e-52 176.6 0.0 1e-51 176.0 0.0 1.3 1 0 0 1 1 1 1 Tn3 transposase DDE domain DUF4158 PF13700.6 AAAP01003688.1_1 - 2.3e-46 157.7 4.9 3.6e-44 150.5 0.7 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4158) FAD_binding_4 PF01565.23 AAAP01003688.1_1 - 0.0069 16.1 0.1 0.023 14.4 0.1 1.9 1 0 0 1 1 1 1 FAD binding domain AbiEi_4 PF13338.6 AAAP01003688.1_1 - 0.41 10.8 3.0 3.9 7.7 0.2 3.9 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin Resolvase PF00239.21 AAAP01003688.1_2 - 4.5e-41 140.4 1.4 5.7e-41 140.0 1.4 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_23 PF13384.6 AAAP01003688.1_2 - 3.5e-06 26.6 0.1 8.1e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003688.1_2 - 0.00043 20.3 1.2 0.0013 18.7 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 AAAP01003688.1_2 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AAAP01003688.1_2 - 0.0006 19.9 0.1 0.0021 18.2 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01003688.1_2 - 0.0007 19.3 0.1 0.0036 17.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_8 PF02954.19 AAAP01003688.1_2 - 0.004 16.9 0.7 0.039 13.8 0.1 2.6 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_40 PF14493.6 AAAP01003688.1_2 - 0.13 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Proton_antipo_M PF00361.20 AAAP01003688.1_3 - 6.5e-67 225.8 15.5 6.5e-67 225.8 15.5 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter CT_C_D PF02682.16 AAAP01003689.1_1 - 1.1e-10 41.6 0.3 1.5e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_A_B PF02626.15 AAAP01003689.1_2 - 1.1e-79 267.8 1.6 1.3e-79 267.5 1.6 1.1 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B LamB_YcsF PF03746.16 AAAP01003689.1_3 - 5.1e-90 301.3 3.9 5.7e-90 301.2 3.9 1.0 1 0 0 1 1 1 1 LamB/YcsF family tRNA-synt_2 PF00152.20 AAAP01003689.1_4 - 7.8e-92 307.7 0.0 9.3e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AAAP01003689.1_4 - 1.1e-16 60.8 0.0 1.9e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 GAD domain Response_reg PF00072.24 AAAP01003690.1_1 - 2.2e-24 85.8 0.0 2.7e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain OKR_DC_1_N PF03709.15 AAAP01003690.1_1 - 0.0013 19.0 0.0 0.0016 18.7 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Response_reg PF00072.24 AAAP01003690.1_2 - 1.2e-19 70.5 0.0 1.7e-18 66.8 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003690.1_2 - 8.9e-19 68.1 0.0 1.6e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 AAAP01003690.1_2 - 6.6e-16 58.9 0.1 3e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 AAAP01003690.1_2 - 1.8e-10 40.7 0.3 1.8e-10 40.7 0.3 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003690.1_2 - 3.6e-09 36.6 0.0 8.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 AAAP01003690.1_2 - 4.7e-09 37.0 0.0 9.1e-08 32.8 0.0 2.9 3 0 0 3 3 3 1 GAF domain PAS_8 PF13188.7 AAAP01003690.1_2 - 4e-08 33.1 0.0 1.2e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAAP01003690.1_2 - 1.1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AAAP01003690.1_2 - 0.0049 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Rhodanese PF00581.20 AAAP01003690.1_2 - 0.014 15.9 0.0 0.19 12.3 0.0 2.6 3 0 0 3 3 3 0 Rhodanese-like domain Autoind_bind PF03472.15 AAAP01003690.1_2 - 0.015 14.8 0.0 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 Autoinducer binding domain HATPase_c_5 PF14501.6 AAAP01003690.1_2 - 0.033 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 GHKL domain FleQ PF06490.11 AAAP01003690.1_2 - 0.078 13.4 0.0 0.28 11.6 0.0 2.0 2 0 0 2 2 1 0 Flagellar regulatory protein FleQ HATPase_c_3 PF13589.6 AAAP01003690.1_2 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M15_2 PF05951.13 AAAP01003690.1_4 - 1.6e-55 187.0 0.0 2e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 AAAP01003690.1_4 - 6.4e-14 52.0 0.0 9.2e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M15 HisKA PF00512.25 AAAP01003691.1_2 - 1.3e-19 69.9 0.0 2.9e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003691.1_2 - 1.9e-13 50.6 0.0 2.8e-07 30.8 0.0 3.2 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003691.1_2 - 1.2e-05 25.5 0.0 0.0013 19.0 0.0 2.7 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003691.1_2 - 0.023 14.7 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 PAS fold PAS_7 PF12860.7 AAAP01003691.1_2 - 0.06 13.5 0.0 12 6.1 0.0 3.0 3 1 0 3 3 3 0 PAS fold ORF_12_N PF18042.1 AAAP01003691.1_2 - 0.06 13.8 0.0 0.37 11.2 0.0 2.3 3 0 0 3 3 3 0 ORF 12 gene product N-terminal PAS_8 PF13188.7 AAAP01003691.1_2 - 0.13 12.3 0.0 2.3 8.4 0.0 2.6 3 0 0 3 3 3 0 PAS domain Response_reg PF00072.24 AAAP01003691.1_3 - 6.1e-23 81.1 0.0 2.2e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003691.1_3 - 2.7e-15 56.8 0.0 4.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003691.1_4 - 6.1e-26 90.8 0.0 1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AAAP01003691.1_4 - 7e-19 68.2 0.9 1e-18 67.7 0.2 1.6 2 0 0 2 2 2 1 HD domain HD_5 PF13487.6 AAAP01003691.1_4 - 4.1e-17 62.2 0.2 8.9e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 HD domain Response_reg PF00072.24 AAAP01003691.1_5 - 3.4e-22 78.7 0.2 3.8e-22 78.6 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain GFO_IDH_MocA PF01408.22 AAAP01003691.1_5 - 0.0052 17.6 0.0 0.0069 17.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Big_9 PF17963.1 AAAP01003692.1_1 - 1.9e-48 163.1 118.5 7.1e-17 61.9 10.2 7.7 7 1 0 7 7 7 6 Bacterial Ig domain Cadherin_5 PF17892.1 AAAP01003692.1_1 - 8.1e-45 150.8 66.6 5.3e-32 109.7 5.4 8.1 5 2 0 6 6 6 6 Cadherin-like domain Cadherin_4 PF17803.1 AAAP01003692.1_1 - 2.3e-29 101.8 115.6 1.6e-11 44.6 7.6 8.6 8 0 0 8 8 8 6 Bacterial cadherin-like domain DUF1659 PF07872.11 AAAP01003692.1_1 - 0.0015 18.1 0.0 0.9 9.3 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1659) Cadherin_3 PF16184.5 AAAP01003692.1_1 - 0.034 14.1 6.6 1.1 9.2 0.8 5.0 5 1 0 5 5 5 0 Cadherin-like Polyketide_cyc2 PF10604.9 AAAP01003692.1_1 - 1 9.6 13.3 0.78 10.0 0.5 4.3 2 2 2 5 5 5 0 Polyketide cyclase / dehydrase and lipid transport PAS_4 PF08448.10 AAAP01003692.1_3 - 5.5e-12 45.9 0.0 6.8e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003692.1_3 - 3.6e-07 30.4 0.0 3.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003692.1_3 - 2.3e-06 27.6 0.0 2.9e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003692.1_3 - 0.0002 21.3 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AAAP01003692.1_3 - 0.06 13.6 0.0 0.39 11.0 0.0 2.1 2 1 0 2 2 2 0 PAS fold POR_N PF01855.19 AAAP01003692.1_4 - 1e-79 267.5 1.0 1.5e-79 267.0 1.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AAAP01003692.1_4 - 4.9e-26 91.9 0.0 8.3e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 AAAP01003692.1_4 - 7.7e-13 48.6 0.2 2.6e-12 46.9 0.1 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AAAP01003692.1_4 - 0.023 14.5 0.2 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain Phage_capsid PF05065.13 AAAP01003693.1_1 - 2.7e-13 49.9 0.0 3.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phage capsid family Stomoxyn PF11585.8 AAAP01003693.1_1 - 0.021 14.8 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn MerR_1 PF13411.6 AAAP01003693.1_2 - 0.033 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF4214 PF13946.6 AAAP01003693.1_2 - 0.09 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) DNA_alkylation PF08713.11 AAAP01003693.1_2 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme HTH_17 PF12728.7 AAAP01003693.1_3 - 0.074 13.2 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain tRNA_Me_trans PF03054.16 AAAP01003693.1_4 - 5.2e-109 364.3 0.0 5.9e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 AAAP01003693.1_4 - 2.8e-07 30.6 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 AAAP01003693.1_4 - 6.8e-05 22.1 0.0 0.00015 21.0 0.0 1.5 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 AAAP01003693.1_4 - 0.0015 18.1 0.4 0.0032 17.0 0.3 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 AAAP01003693.1_4 - 0.013 14.8 0.4 0.075 12.3 0.4 1.9 1 1 0 1 1 1 0 Arginosuccinate synthase DUF3659 PF12396.8 AAAP01003693.1_4 - 0.098 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) ATP_bind_3 PF01171.20 AAAP01003693.1_4 - 0.12 12.2 0.3 0.29 10.9 0.2 1.7 2 0 0 2 2 2 0 PP-loop family Methyltransf_11 PF08241.12 AAAP01003693.1_5 - 1.2e-06 29.0 0.0 2.5e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003693.1_5 - 0.00035 20.4 0.0 0.00073 19.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003693.1_5 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AAAP01003693.1_5 - 0.073 13.8 0.0 0.16 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF599 PF04654.12 AAAP01003693.1_6 - 4.1e-58 196.3 13.4 4.6e-58 196.1 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Fe-S_assembly PF04384.13 AAAP01003693.1_7 - 1.1e-33 115.7 1.2 1.1e-33 115.6 1.2 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster assembly Fer2 PF00111.27 AAAP01003693.1_8 - 2.1e-15 56.4 0.1 2.6e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HSP70 PF00012.20 AAAP01003693.1_9 - 1.8e-27 95.8 0.1 2e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein ATE_C PF04377.15 AAAP01003694.1_1 - 4.8e-35 121.1 0.0 6.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 AAAP01003694.1_1 - 3.9e-13 49.6 0.0 9.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 AAAP01003694.1_1 - 0.001 19.2 0.7 0.0019 18.4 0.7 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RDD PF06271.12 AAAP01003694.1_2 - 6.9e-17 62.0 7.8 8.7e-17 61.6 7.8 1.1 1 0 0 1 1 1 1 RDD family EcsB PF05975.12 AAAP01003694.1_2 - 0.095 11.5 3.8 0.12 11.3 3.8 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB VirB3 PF05101.13 AAAP01003694.1_2 - 4.6 7.5 11.5 14 6.0 0.3 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein MotB_plug PF13677.6 AAAP01003694.1_3 - 9.2e-17 60.4 0.2 9.2e-17 60.4 0.2 1.6 2 0 0 2 2 2 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAAP01003694.1_3 - 2.1e-12 47.2 0.0 3.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 OmpA family PTS_IIA PF02255.16 AAAP01003694.1_3 - 0.19 11.8 0.2 0.32 11.1 0.2 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit MotA_ExbB PF01618.16 AAAP01003694.1_4 - 6.8e-11 42.0 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Flavin_Reduct PF01613.18 AAAP01003694.1_6 - 3.1e-41 141.0 0.0 3.9e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Penicil_amidase PF01804.18 AAAP01003694.1_7 - 1.9e-59 202.3 0.2 2.2e-59 202.1 0.2 1.0 1 0 0 1 1 1 1 Penicillin amidase DUF4032 PF13224.6 AAAP01003694.1_7 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) DUF2390 PF09523.10 AAAP01003694.1_7 - 0.085 13.2 0.1 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Inositol_P PF00459.25 AAAP01003695.1_1 - 2.3e-25 89.7 0.0 2.4e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family GTP-bdg_M PF16360.5 AAAP01003695.1_2 - 6.5e-30 103.6 4.8 6.5e-30 103.6 4.8 2.2 2 0 0 2 2 2 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 AAAP01003695.1_2 - 1.4e-25 89.8 0.0 4.2e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AAAP01003695.1_2 - 4.3e-20 71.9 0.1 4.8e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01003695.1_2 - 4.8e-06 26.6 0.0 0.099 12.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AAAP01003695.1_2 - 5.6e-05 22.7 0.8 0.00018 21.0 0.4 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAAP01003695.1_2 - 0.00047 20.3 0.0 0.0051 16.9 0.0 2.3 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 AAAP01003695.1_2 - 0.0006 20.2 0.7 0.0023 18.3 0.3 2.2 1 1 2 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.27 AAAP01003695.1_2 - 0.0036 16.9 0.1 2.8 7.5 0.1 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain cobW PF02492.19 AAAP01003695.1_2 - 0.0082 15.7 3.0 0.43 10.2 0.2 2.6 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 AAAP01003695.1_2 - 0.018 15.6 0.0 0.049 14.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Arf PF00025.21 AAAP01003695.1_2 - 0.023 14.1 0.6 0.39 10.2 0.6 2.4 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.6 AAAP01003695.1_2 - 0.044 14.0 0.1 1.6 8.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 AAAP01003695.1_2 - 0.096 12.7 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 AAAP01003695.1_2 - 0.099 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 AAAP01003695.1_2 - 0.14 11.9 0.0 21 4.8 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MRNIP PF15749.5 AAAP01003695.1_2 - 0.14 12.9 0.0 0.35 11.6 0.0 1.7 2 0 0 2 2 2 0 MRN-interacting protein GST_C_2 PF13410.6 AAAP01003695.1_2 - 0.23 11.5 0.7 44 4.2 0.2 3.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Hfq PF17209.3 AAAP01003695.1_3 - 5.4e-33 112.5 0.1 6.4e-33 112.2 0.1 1.1 1 0 0 1 1 1 1 Hfq protein HAD_2 PF13419.6 AAAP01003695.1_4 - 2e-29 103.0 0.0 2.2e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003695.1_4 - 2.4e-07 31.3 0.1 4.5e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003695.1_4 - 7.6e-06 26.4 0.2 0.00022 21.6 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01003695.1_4 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TrkA_N PF02254.18 AAAP01003695.1_5 - 8.5e-52 174.3 7.2 2.6e-27 95.4 0.2 2.7 3 0 0 3 3 2 2 TrkA-N domain TrkA_C PF02080.21 AAAP01003695.1_5 - 6.7e-28 96.3 2.6 1.2e-16 60.2 0.1 2.8 3 0 0 3 3 2 2 TrkA-C domain NAD_binding_7 PF13241.6 AAAP01003695.1_5 - 3.6e-09 37.0 2.7 0.001 19.5 0.4 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding XdhC_C PF13478.6 AAAP01003695.1_5 - 1.7e-08 35.0 1.0 0.0031 18.0 0.1 2.6 2 0 0 2 2 2 2 XdhC Rossmann domain Pyr_redox PF00070.27 AAAP01003695.1_5 - 3.3e-08 34.0 1.9 0.0013 19.3 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AAAP01003695.1_5 - 1.2e-07 32.2 3.3 0.0077 16.8 0.2 3.6 4 0 0 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 AAAP01003695.1_5 - 2.1e-07 30.5 0.6 0.0067 15.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 AAAP01003695.1_5 - 6.4e-07 29.4 3.9 0.00027 20.9 0.2 2.3 2 0 0 2 2 2 2 NAD(P)H-binding GFO_IDH_MocA PF01408.22 AAAP01003695.1_5 - 1.3e-06 29.2 1.2 0.0021 18.9 0.1 3.0 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold DAO PF01266.24 AAAP01003695.1_5 - 2.6e-06 27.2 0.6 0.02 14.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 AAAP01003695.1_5 - 2.1e-05 24.8 1.7 0.13 12.6 0.1 2.6 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AAAP01003695.1_5 - 2.4e-05 24.0 0.6 0.026 14.1 0.1 2.8 3 0 0 3 3 2 2 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 AAAP01003695.1_5 - 2.8e-05 23.0 0.1 0.044 12.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein 3HCDH_N PF02737.18 AAAP01003695.1_5 - 2.9e-05 24.0 2.5 0.0013 18.6 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAAP01003695.1_5 - 5.1e-05 22.7 4.8 0.0011 18.3 0.8 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 AAAP01003695.1_5 - 8.6e-05 22.6 1.4 0.15 12.1 0.1 2.7 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 AAAP01003695.1_5 - 9.4e-05 21.6 0.1 0.042 12.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DUF1188 PF06690.11 AAAP01003695.1_5 - 0.00012 21.7 0.1 0.12 11.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) NAD_Gly3P_dh_N PF01210.23 AAAP01003695.1_5 - 0.00013 22.0 0.4 0.048 13.6 0.1 2.6 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Castor_Poll_mid PF06241.12 AAAP01003695.1_5 - 0.00033 20.6 0.0 0.57 10.2 0.0 2.6 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel Ldh_1_N PF00056.23 AAAP01003695.1_5 - 0.00039 20.5 2.7 0.056 13.5 0.5 2.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AAAP01003695.1_5 - 0.0004 20.5 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 AAAP01003695.1_5 - 0.00055 19.6 0.4 0.046 13.3 0.1 2.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 AAAP01003695.1_5 - 0.00064 19.3 4.9 0.0077 15.8 0.4 2.3 2 0 0 2 2 2 1 NmrA-like family NAD_binding_2 PF03446.15 AAAP01003695.1_5 - 0.00073 19.7 1.1 0.068 13.3 0.2 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 AAAP01003695.1_5 - 0.0011 18.3 0.2 1.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 AAAP01003695.1_5 - 0.031 13.5 0.1 4.8 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Epimerase PF01370.21 AAAP01003695.1_5 - 0.042 13.3 0.5 0.35 10.3 0.1 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AA_kinase PF00696.28 AAAP01003695.1_5 - 0.06 12.9 3.2 0.61 9.6 0.1 2.5 2 1 0 2 2 2 0 Amino acid kinase family adh_short PF00106.25 AAAP01003695.1_5 - 0.064 12.7 1.1 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase LYTB PF02401.18 AAAP01003695.1_5 - 0.082 12.2 0.1 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 LytB protein Sigma54_activat PF00158.26 AAAP01003695.1_6 - 1.2e-56 191.0 0.0 1.8e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01003695.1_6 - 2.7e-23 82.6 0.0 4.4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01003695.1_6 - 2e-08 33.9 0.2 5.7e-08 32.4 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAAP01003695.1_6 - 2.3e-06 27.6 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAAP01003695.1_6 - 3.8e-05 23.2 0.5 0.04 13.3 0.1 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AAAP01003695.1_6 - 0.00029 21.3 0.0 0.00081 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAAP01003695.1_6 - 0.00037 20.9 0.0 0.0008 19.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01003695.1_6 - 0.0063 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAAP01003695.1_6 - 0.035 14.4 0.2 0.27 11.5 0.2 2.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAAP01003695.1_6 - 0.06 12.5 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF2766 PF10964.8 AAAP01003695.1_6 - 0.081 12.9 0.1 19 5.3 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2766) RNA12 PF10443.9 AAAP01003695.1_6 - 0.1 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_18 PF13238.6 AAAP01003695.1_6 - 0.12 12.9 0.0 0.26 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01003695.1_6 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Helicase_C PF00271.31 AAAP01003696.1_1 - 3.9e-17 62.6 0.0 6.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UPF0016 PF01169.19 AAAP01003696.1_2 - 1.9e-41 140.2 21.7 2e-21 76.1 5.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 AAAP01003696.1_2 - 0.022 14.4 19.2 0.016 14.9 4.5 2.7 1 1 2 3 3 3 0 Sulfite exporter TauE/SafE Cation_efflux PF01545.21 AAAP01003696.1_3 - 3e-46 157.7 7.8 3.8e-46 157.3 7.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003696.1_3 - 7.5e-29 99.7 7.7 2.8e-09 37.0 0.1 3.3 3 0 0 3 3 3 3 Dimerisation domain of Zinc Transporter RHH_1 PF01402.21 AAAP01003696.1_3 - 0.12 12.3 3.9 1.3 9.0 0.0 3.7 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family UvrA_DNA-bind PF17755.1 AAAP01003696.1_4 - 2e-39 134.3 0.0 1e-37 128.8 0.0 2.5 2 0 0 2 2 2 1 UvrA DNA-binding domain UvrA_inter PF17760.1 AAAP01003696.1_4 - 3.3e-37 126.9 0.0 7e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 UvrA interaction domain ABC_tran PF00005.27 AAAP01003696.1_4 - 4.2e-19 69.4 0.1 4.8e-05 23.9 0.0 4.3 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 AAAP01003696.1_4 - 7e-09 35.4 0.0 0.029 13.8 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003696.1_4 - 3.5e-07 30.8 0.1 0.064 13.6 0.0 3.3 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 AAAP01003696.1_4 - 4.5e-06 26.3 0.3 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 AAAP01003696.1_4 - 1.6e-05 24.6 0.3 0.18 11.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 AAAP01003696.1_4 - 0.00013 21.9 4.6 0.0037 17.1 0.1 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01003696.1_4 - 0.00035 20.5 0.1 0.51 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 AAAP01003696.1_4 - 0.00069 20.2 0.2 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAAP01003696.1_4 - 0.002 18.4 0.3 3.1 8.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain BCA_ABC_TP_C PF12399.8 AAAP01003696.1_4 - 0.0026 17.7 0.8 0.023 14.6 0.1 2.5 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter DnaJ_CXXCXGXG PF00684.19 AAAP01003696.1_4 - 0.0029 18.0 4.0 0.037 14.4 0.4 3.2 3 0 0 3 3 3 1 DnaJ central domain ATPase PF06745.13 AAAP01003696.1_4 - 0.0046 16.3 0.1 2.3 7.5 0.1 2.5 2 0 0 2 2 2 2 KaiC AAA_18 PF13238.6 AAAP01003696.1_4 - 0.0078 16.8 0.0 5.5 7.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AAAP01003696.1_4 - 0.0089 15.9 0.7 1.3 8.9 0.0 3.0 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_33 PF13671.6 AAAP01003696.1_4 - 0.021 15.0 0.4 3.4 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 AAAP01003696.1_4 - 0.028 13.7 0.1 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 AAAP01003696.1_4 - 0.034 14.2 0.0 3.3 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 AAAP01003696.1_4 - 0.079 12.9 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 AAAP01003696.1_4 - 0.085 12.6 0.1 20 4.7 0.0 3.6 4 0 0 4 4 4 0 AAA ATPase domain AAA_30 PF13604.6 AAAP01003696.1_4 - 0.16 11.7 0.3 45 3.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 AAAP01003696.1_4 - 0.19 11.3 1.2 12 5.4 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Anti-TRAP PF15777.5 AAAP01003696.1_4 - 0.9 9.6 3.5 8.4 6.4 0.3 3.2 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein OmpA PF00691.20 AAAP01003696.1_5 - 4.7e-15 55.8 0.1 5.7e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 OmpA family SBP_bac_5 PF00496.22 AAAP01003696.1_5 - 0.021 13.8 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle CheZ PF04344.13 AAAP01003697.1_1 - 4.8e-13 49.5 1.5 5.4e-09 36.3 0.0 2.4 3 0 0 3 3 3 2 Chemotaxis phosphatase, CheZ DUF3418 PF11898.8 AAAP01003697.1_1 - 0.018 13.7 0.2 0.022 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Bcl-2_3 PF15286.6 AAAP01003697.1_1 - 0.035 14.8 0.0 0.053 14.2 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like zf-C4H2 PF10146.9 AAAP01003697.1_1 - 0.089 13.1 0.4 0.16 12.3 0.1 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein DUF948 PF06103.11 AAAP01003697.1_1 - 0.1 12.9 2.4 0.88 9.9 0.2 2.9 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HD PF01966.22 AAAP01003697.1_2 - 6.7e-16 58.6 0.0 9.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01003697.1_2 - 1.9e-15 56.9 0.0 3.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 HD domain Response_reg PF00072.24 AAAP01003697.1_2 - 0.00068 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HDOD PF08668.12 AAAP01003697.1_2 - 0.04 13.4 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 HDOD domain Phage_integrase PF00589.22 AAAP01003697.1_3 - 1.8e-30 106.0 0.2 2.7e-30 105.4 0.2 1.3 1 0 0 1 1 1 1 Phage integrase family DUF2188 PF09954.9 AAAP01003697.1_3 - 0.012 15.8 0.0 2.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Integrase_1 PF12835.7 AAAP01003697.1_3 - 0.021 14.9 0.1 0.12 12.5 0.0 2.1 2 1 0 2 2 2 0 Integrase Arm-DNA-bind_4 PF14657.6 AAAP01003697.1_3 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain rve PF00665.26 AAAP01003697.1_7 - 4.5e-26 91.4 0.0 5.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01003697.1_7 - 6.7e-22 77.0 0.2 1.1e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AAAP01003697.1_7 - 0.00046 20.3 0.0 0.002 18.3 0.0 2.0 1 1 1 2 2 2 1 Integrase core domain EAL PF00563.20 AAAP01003698.1_2 - 2.1e-68 230.4 0.0 4.3e-68 229.4 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003698.1_2 - 2.5e-55 186.6 0.7 1.1e-54 184.6 0.1 2.1 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003698.1_2 - 1.7e-36 124.6 0.0 4.1e-14 52.7 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AAAP01003698.1_2 - 2.7e-36 124.0 0.0 5.4e-14 52.1 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AAAP01003698.1_2 - 2.3e-33 114.7 1.1 2e-12 47.3 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 AAAP01003698.1_2 - 3.4e-21 74.8 0.1 3.2e-06 27.0 0.0 4.0 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 AAAP01003698.1_2 - 6e-18 64.9 0.0 1.9e-10 40.9 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_7 PF12860.7 AAAP01003698.1_2 - 0.0011 19.1 0.2 5.3 7.2 0.0 4.7 5 0 0 5 5 5 1 PAS fold UBA_4 PF14555.6 AAAP01003698.1_2 - 0.16 11.8 0.1 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain OTCace_N PF02729.21 AAAP01003698.1_3 - 1.7e-43 148.2 0.0 2.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AAAP01003698.1_3 - 0.00065 19.8 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Fer2_4 PF13510.6 AAAP01003698.1_3 - 0.013 15.5 0.0 0.058 13.5 0.0 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DeoC PF01791.9 AAAP01003698.1_3 - 0.021 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 DeoC/LacD family aldolase PK PF00224.21 AAAP01003699.1_1 - 5.7e-100 334.6 0.0 7.8e-100 334.1 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAAP01003699.1_1 - 9.6e-33 112.9 1.6 2.2e-32 111.8 1.6 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DsrD PF08679.11 AAAP01003699.1_1 - 0.041 14.1 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) DUF4253 PF14062.6 AAAP01003699.1_1 - 0.045 13.9 0.1 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) MCPsignal PF00015.21 AAAP01003699.1_2 - 3e-29 102.0 13.9 2.5e-27 95.8 7.9 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Diacid_rec PF05651.13 AAAP01003699.1_2 - 2.2e-20 72.7 0.1 6.7e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Putative sugar diacid recognition DUF948 PF06103.11 AAAP01003699.1_2 - 0.0011 19.1 4.1 1.7 9.0 0.1 3.8 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 AAAP01003699.1_2 - 0.0067 16.8 4.3 0.019 15.4 1.4 2.5 2 1 1 3 3 3 1 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.12 AAAP01003699.1_2 - 0.0097 16.0 4.3 1.2 9.2 0.4 2.8 2 2 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 AAAP01003699.1_2 - 0.01 15.4 4.8 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain EzrA PF06160.12 AAAP01003699.1_2 - 0.015 13.5 0.1 0.096 10.8 0.2 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Serine_rich PF08824.10 AAAP01003699.1_2 - 0.015 15.3 0.5 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF2203 PF09969.9 AAAP01003699.1_2 - 0.021 15.5 1.5 0.28 11.9 0.4 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 AAAP01003699.1_2 - 0.041 13.9 0.7 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 AAAP01003699.1_2 - 0.058 13.8 0.6 0.19 12.2 0.5 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Dor1 PF04124.12 AAAP01003699.1_2 - 0.086 11.5 0.2 4 6.0 0.1 2.1 2 0 0 2 2 2 0 Dor1-like family Seryl_tRNA_N PF02403.22 AAAP01003699.1_2 - 0.11 12.8 0.5 51 4.2 0.0 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 AAAP01003699.1_2 - 0.13 12.3 3.5 3.1 7.8 1.2 2.6 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 AAAP01003699.1_2 - 0.16 12.4 1.4 6.3 7.3 0.5 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 AAAP01003699.1_2 - 0.18 11.7 0.2 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Sec34-like family Spc7 PF08317.11 AAAP01003699.1_2 - 0.18 10.6 0.9 1.9 7.3 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 AAAP01003699.1_2 - 0.23 10.1 0.3 0.53 8.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain COG5 PF10392.9 AAAP01003699.1_2 - 0.3 11.3 1.6 3.2 7.9 0.6 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Med7 PF05983.11 AAAP01003699.1_2 - 0.38 10.8 0.8 7.4 6.6 0.2 2.2 2 0 0 2 2 2 0 MED7 protein HrpB7 PF09486.10 AAAP01003699.1_2 - 0.4 11.0 13.1 0.74 10.2 1.0 2.7 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) YscO PF07321.12 AAAP01003699.1_2 - 0.92 9.4 5.3 24 4.8 0.0 2.5 2 0 0 2 2 2 0 Type III secretion protein YscO cNMP_binding PF00027.29 AAAP01003699.1_3 - 4.4e-12 45.9 0.0 6.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003699.1_3 - 5.7e-10 39.0 0.3 1.3e-09 37.9 0.1 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003699.1_3 - 2e-06 27.3 0.4 0.00029 20.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, crp family DUF746 PF05344.11 AAAP01003699.1_3 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) AAA_2 PF07724.14 AAAP01003699.1_4 - 5.7e-38 130.7 0.1 1.8e-35 122.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAAP01003699.1_4 - 5.1e-36 122.7 0.2 5.1e-36 122.7 0.2 2.4 3 0 0 3 3 2 1 AAA lid domain Clp_N PF02861.20 AAAP01003699.1_4 - 1e-22 80.0 6.8 5.1e-12 45.7 1.9 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 AAAP01003699.1_4 - 3.2e-22 79.4 0.0 2.5e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003699.1_4 - 1.7e-18 66.9 0.0 9.6e-12 45.1 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003699.1_4 - 3.4e-12 47.1 5.2 6.8e-05 23.3 0.1 4.8 3 3 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 AAAP01003699.1_4 - 8.1e-10 39.1 1.6 0.013 15.8 0.0 4.8 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 AAAP01003699.1_4 - 4.7e-07 29.7 0.1 0.00047 19.9 0.0 3.0 3 1 0 3 3 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 AAAP01003699.1_4 - 6.4e-07 29.3 0.1 0.074 12.8 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein TniB PF05621.11 AAAP01003699.1_4 - 1.3e-06 28.0 0.0 0.001 18.5 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 AAAP01003699.1_4 - 2.6e-06 27.1 0.0 0.0078 15.7 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AAAP01003699.1_4 - 3.3e-05 24.4 0.0 0.3 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 AAAP01003699.1_4 - 0.00011 21.9 1.6 2.1 8.0 0.0 4.0 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 AAAP01003699.1_4 - 0.00012 22.3 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 AAAP01003699.1_4 - 0.00014 21.8 0.3 3 7.7 0.1 4.1 2 2 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 AAAP01003699.1_4 - 0.0002 21.6 4.9 0.6 10.3 0.1 4.1 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 AAAP01003699.1_4 - 0.00028 20.9 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 AAAP01003699.1_4 - 0.00031 20.4 0.2 0.026 14.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AAAP01003699.1_4 - 0.00074 19.9 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 AAAP01003699.1_4 - 0.0011 18.4 0.6 1.2 8.5 0.1 3.1 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AAAP01003699.1_4 - 0.0012 18.8 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AAAP01003699.1_4 - 0.0032 17.2 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AAAP01003699.1_4 - 0.0038 17.2 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 AAAP01003699.1_4 - 0.0042 17.6 0.2 2.2 8.8 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 AAAP01003699.1_4 - 0.0044 17.5 6.2 5.9 7.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 AAAP01003699.1_4 - 0.0073 16.6 0.1 0.044 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA C-terminal domain ResIII PF04851.15 AAAP01003699.1_4 - 0.0076 16.3 0.0 22 5.0 0.0 3.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 AAAP01003699.1_4 - 0.012 15.4 0.0 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 AAAP01003699.1_4 - 0.015 15.2 0.0 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Bacterial dnaA protein NTPase_1 PF03266.15 AAAP01003699.1_4 - 0.016 15.2 0.2 12 5.8 0.0 3.5 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 AAAP01003699.1_4 - 0.017 15.4 0.2 2.8 8.3 0.1 3.2 3 1 0 4 4 2 0 AAA domain DUF815 PF05673.13 AAAP01003699.1_4 - 0.017 14.3 0.0 2.2 7.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 AAAP01003699.1_4 - 0.021 14.6 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit T2SSE PF00437.20 AAAP01003699.1_4 - 0.025 13.7 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 AAAP01003699.1_4 - 0.031 13.5 0.1 5.2 6.3 0.0 3.0 2 1 1 3 3 3 0 Zeta toxin AAA_3 PF07726.11 AAAP01003699.1_4 - 0.036 13.9 0.1 20 5.0 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAAP01003699.1_4 - 0.047 13.9 0.0 20 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 AAAP01003699.1_4 - 0.049 13.2 0.0 18 4.9 0.0 3.3 4 0 0 4 4 3 0 Ras family ATP_bind_1 PF03029.17 AAAP01003699.1_4 - 0.069 12.9 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein L_lactis_ph-MCP PF06673.11 AAAP01003699.1_4 - 0.098 11.6 0.4 16 4.4 0.0 3.1 3 0 0 3 3 3 0 Lactococcus lactis bacteriophage major capsid protein PduV-EutP PF10662.9 AAAP01003699.1_4 - 0.12 12.1 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MscS_porin PF12795.7 AAAP01003699.1_4 - 0.44 10.0 7.4 3.5 7.1 5.7 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Herpes_BLRF2 PF05812.12 AAAP01003699.1_4 - 0.65 10.1 3.6 2.6 8.2 2.3 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein HTH_ParB PF17762.1 AAAP01003700.1_1 - 0.054 13.3 0.2 0.062 13.1 0.2 1.1 1 0 0 1 1 1 0 HTH domain found in ParB protein Mob_Pre PF01076.19 AAAP01003700.1_2 - 1.7e-12 47.6 0.0 4.6e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Plasmid recombination enzyme Chlor_dismutase PF06778.12 AAAP01003700.1_3 - 7.2e-34 117.1 0.2 1e-33 116.6 0.2 1.3 1 0 0 1 1 1 1 Chlorite dismutase AsnC_trans_reg PF01037.21 AAAP01003700.1_3 - 0.016 15.2 0.1 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Molybdopterin PF00384.22 AAAP01003700.1_4 - 6.4e-63 213.2 0.0 8.7e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 AAAP01003700.1_4 - 3.9e-06 26.7 0.1 1.1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AAAP01003700.1_4 - 0.0006 19.5 0.5 0.0023 17.7 0.5 2.1 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence DUF1833 PF08875.11 AAAP01003701.1_1 - 4e-72 240.7 0.1 4.6e-72 240.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1833) DUF736 PF05284.12 AAAP01003701.1_1 - 0.012 15.5 0.0 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF736) Malate_synthase PF01274.22 AAAP01003701.1_2 - 0.088 11.1 0.1 0.1 10.9 0.1 1.0 1 0 0 1 1 1 0 Malate synthase LppA PF16708.5 AAAP01003701.1_3 - 0.14 12.1 3.3 0.23 11.4 2.2 1.8 1 1 1 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DUF1664 PF07889.12 AAAP01003701.1_3 - 0.19 11.7 1.0 0.26 11.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CiPC PF15800.5 AAAP01003701.1_7 - 2.3 7.9 13.2 3 7.5 13.2 1.2 1 0 0 1 1 1 0 Clock interacting protein circadian FAM196 PF15265.6 AAAP01003701.1_7 - 4.1 6.8 13.8 4.8 6.6 13.8 1.1 1 0 0 1 1 1 0 FAM196 family AMP-binding PF00501.28 AAAP01003702.1_3 - 2.3e-93 313.1 0.1 2.9e-93 312.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003702.1_3 - 3.1e-23 82.5 0.1 6.6e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GGDEF PF00990.21 AAAP01003702.1_5 - 2e-06 27.6 0.0 2.9e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DAGK_cat PF00781.24 AAAP01003702.1_6 - 4.6e-19 68.3 0.1 6.3e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AAAP01003702.1_6 - 0.011 15.0 0.5 0.016 14.4 0.1 1.4 2 0 0 2 2 2 0 ATP-NAD kinase Metallophos PF00149.28 AAAP01003702.1_7 - 1.4e-14 55.0 1.8 4.7e-14 53.4 1.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01003702.1_7 - 2.1e-13 50.8 0.1 3.8e-13 50.0 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AAAP01003702.1_7 - 0.028 13.7 0.0 0.45 9.8 0.0 2.2 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Glyco_transf_41 PF13844.6 AAAP01003702.1_8 - 8e-36 123.5 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_2 PF07719.17 AAAP01003702.1_8 - 2.1e-19 68.0 5.7 3.1e-05 23.8 0.1 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003702.1_8 - 7.4e-19 68.1 20.0 9.3e-09 35.8 0.2 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003702.1_8 - 2.4e-17 63.2 15.0 1.3e-05 25.6 0.3 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003702.1_8 - 6e-17 60.7 0.6 0.00063 19.5 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003702.1_8 - 6.8e-17 60.7 24.8 4.5e-05 23.9 1.2 6.9 2 1 5 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003702.1_8 - 8e-14 50.6 0.2 0.00029 20.8 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003702.1_8 - 6.2e-12 45.0 0.9 0.0077 15.9 0.0 4.0 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.6 AAAP01003702.1_8 - 9e-11 41.9 12.4 0.0006 20.1 0.1 4.4 1 1 4 5 5 5 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003702.1_8 - 2.9e-09 37.0 0.3 0.00082 19.5 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 AAAP01003702.1_8 - 4.6e-08 32.9 2.3 0.11 12.9 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003702.1_8 - 2.7e-07 30.5 23.3 0.0012 19.3 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003702.1_8 - 2.4e-06 27.6 22.9 1.1e-05 25.4 1.7 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.17 AAAP01003702.1_8 - 6.5e-06 26.6 10.7 0.0016 18.9 2.4 4.0 2 1 3 5 5 5 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 AAAP01003702.1_8 - 9.7e-06 25.9 8.2 0.081 13.6 0.5 5.8 7 1 0 7 7 6 1 Tetratricopeptide repeat NARP1 PF12569.8 AAAP01003702.1_8 - 5.6e-05 22.3 0.2 0.00085 18.4 0.0 2.5 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 AAAP01003702.1_8 - 0.00013 21.7 5.7 0.022 14.8 0.0 4.5 6 1 1 7 7 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003702.1_8 - 0.00095 18.4 6.9 0.05 12.8 1.4 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003702.1_8 - 0.0024 17.7 16.3 1 9.3 1.1 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003702.1_8 - 0.0043 17.4 7.8 0.02 15.2 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AAAP01003702.1_8 - 0.0043 16.7 5.5 0.024 14.3 0.3 3.0 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) T6SS_VasJ PF16989.5 AAAP01003702.1_8 - 0.042 13.3 0.9 0.79 9.1 0.1 2.3 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_21 PF09976.9 AAAP01003702.1_8 - 0.058 13.1 2.5 1.5 8.5 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 AAAP01003702.1_8 - 0.075 13.1 1.9 2.8 8.1 0.3 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TP_methylase PF00590.20 AAAP01003703.1_1 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiX PF01903.17 AAAP01003703.1_2 - 1.3e-27 96.2 0.0 6.6e-13 48.9 0.0 2.0 2 0 0 2 2 2 2 CbiX TauD PF02668.16 AAAP01003703.1_4 - 6.3e-14 52.4 0.1 7.7e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 AAAP01003703.1_4 - 0.0031 16.7 0.0 0.022 13.9 0.0 2.0 1 1 0 1 1 1 1 CsiD zf-SCNM1 PF15803.5 AAAP01003703.1_4 - 0.072 12.7 0.1 6.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 NIR_SIR PF01077.22 AAAP01003703.1_5 - 2.6e-32 111.5 0.1 4e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01003703.1_5 - 4e-08 33.0 0.0 9.7e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Fer4_7 PF12838.7 AAAP01003703.1_5 - 0.00057 20.4 6.2 0.022 15.3 6.3 2.6 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003703.1_5 - 0.0086 16.2 2.3 0.0086 16.2 2.3 2.7 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003703.1_5 - 0.013 15.7 11.6 0.12 12.5 3.3 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003703.1_5 - 0.024 15.2 4.8 0.087 13.4 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 AAAP01003703.1_5 - 1.1 9.4 11.7 0.25 11.5 2.4 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003703.1_5 - 1.2 10.0 7.5 12 6.8 0.7 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003703.1_5 - 1.9 9.0 10.4 24 5.5 10.5 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003703.1_5 - 3.2 8.4 7.9 6.3 7.4 0.6 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain NIR_SIR PF01077.22 AAAP01003703.1_6 - 4.5e-27 94.5 0.0 6.3e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AAAP01003703.1_6 - 4.7e-10 39.2 0.0 2.4e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Fer4_21 PF14697.6 AAAP01003703.1_6 - 0.83 9.8 14.0 0.076 13.2 7.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003703.1_6 - 1.6 9.0 12.4 0.084 13.1 6.8 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003703.1_6 - 4.6 7.2 14.1 2.9 7.9 8.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003703.1_6 - 4.7 7.9 13.1 13 6.4 13.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain DrsE PF02635.15 AAAP01003703.1_7 - 1.4e-30 106.1 0.0 1.5e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family GSH-S_N PF02951.14 AAAP01003703.1_7 - 0.16 12.1 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain DrsE PF02635.15 AAAP01003703.1_8 - 3.5e-18 66.1 0.0 4.2e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family Peptidase_M48 PF01435.18 AAAP01003704.1_1 - 4.4e-23 82.1 0.6 5.6e-23 81.8 0.6 1.0 1 0 0 1 1 1 1 Peptidase family M48 G_glu_transpept PF01019.21 AAAP01003704.1_2 - 4.9e-70 236.8 0.3 2.2e-61 208.2 0.2 3.0 2 1 0 2 2 2 2 Gamma-glutamyltranspeptidase Aminotran_1_2 PF00155.21 AAAP01003704.1_3 - 1.2e-58 199.1 0.0 1.3e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AAAP01003704.1_3 - 0.0002 20.3 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 AAAP01003704.1_3 - 0.0021 17.4 0.0 0.005 16.2 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PALP PF00291.25 AAAP01003704.1_3 - 0.0035 16.8 0.3 0.037 13.4 0.2 2.3 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Aminotran_3 PF00202.21 AAAP01003704.1_3 - 0.021 13.5 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Alliinase_C PF04864.13 AAAP01003704.1_3 - 0.028 13.3 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Allinase DUF3325 PF11804.8 AAAP01003704.1_3 - 0.036 14.2 0.3 0.19 11.9 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3325) Unstab_antitox PF09720.10 AAAP01003704.1_3 - 0.46 10.6 2.4 6.3 6.9 0.2 2.5 2 0 0 2 2 2 0 Putative addiction module component Flg_bbr_C PF06429.13 AAAP01003704.1_4 - 4.1e-15 55.7 1.1 1.4e-14 54.0 1.1 2.0 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal GPI-anchored PF10342.9 AAAP01003704.1_4 - 0.018 15.8 15.4 0.036 14.8 0.8 4.2 3 1 1 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MCPsignal PF00015.21 AAAP01003705.1_1 - 1.9e-30 105.9 23.3 2.9e-30 105.4 23.3 1.5 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.8 AAAP01003705.1_1 - 0.00024 20.5 2.5 0.00029 20.2 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) zf-ZPR1 PF03367.13 AAAP01003705.1_1 - 0.0036 17.2 0.6 0.0047 16.8 0.6 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain DUF948 PF06103.11 AAAP01003705.1_1 - 0.0042 17.3 7.3 0.43 10.9 7.3 2.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003705.1_1 - 0.027 14.5 4.2 0.31 11.1 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vps53_N PF04100.12 AAAP01003705.1_1 - 0.027 13.5 3.6 0.044 12.7 3.0 1.5 1 1 1 2 2 2 0 Vps53-like, N-terminal Prenyltransf PF01255.19 AAAP01003705.1_1 - 0.039 13.5 0.9 0.051 13.1 0.9 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Ferritin PF00210.24 AAAP01003705.1_1 - 0.045 13.7 0.2 0.062 13.2 0.2 1.4 1 1 0 1 1 1 0 Ferritin-like domain MitMem_reg PF13012.6 AAAP01003705.1_1 - 0.11 12.9 1.4 0.27 11.7 1.4 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF211 PF02680.14 AAAP01003705.1_1 - 0.15 12.3 3.2 0.14 12.4 1.1 2.0 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 Laminin_II PF06009.12 AAAP01003705.1_1 - 0.22 11.6 7.9 0.4 10.7 2.3 2.2 1 1 1 2 2 2 0 Laminin Domain II LXG PF04740.12 AAAP01003705.1_1 - 0.23 11.2 4.1 7.9 6.1 4.1 2.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily WXG100 PF06013.12 AAAP01003705.1_1 - 0.45 10.8 8.1 0.27 11.5 5.0 2.2 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF2203 PF09969.9 AAAP01003705.1_1 - 1.2 9.9 4.0 6.1 7.6 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) T7SS_ESX_EspC PF10824.8 AAAP01003705.1_1 - 8.5 6.9 16.0 1.7 9.1 9.3 2.6 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm dTDP_sugar_isom PF00908.17 AAAP01003705.1_2 - 4.7e-64 215.1 0.0 5.2e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Glycos_transf_2 PF00535.26 AAAP01003705.1_3 - 7.7e-22 77.9 0.0 1.3e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Methyltransf_23 PF13489.6 AAAP01003705.1_3 - 1.5e-10 41.2 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003705.1_3 - 0.00035 21.2 0.0 0.00097 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003705.1_3 - 0.00091 19.1 0.3 0.0016 18.3 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAAP01003705.1_3 - 0.0014 18.2 0.0 0.0035 17.0 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 AAAP01003705.1_3 - 0.0033 18.2 0.2 0.015 16.0 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003705.1_3 - 0.0035 17.9 0.3 0.011 16.3 0.2 2.0 2 1 0 2 2 2 1 Methyltransferase domain Glyco_tranf_2_3 PF13641.6 AAAP01003705.1_3 - 0.0072 16.2 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CMAS PF02353.20 AAAP01003705.1_3 - 0.013 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MCPsignal PF00015.21 AAAP01003705.1_6 - 7.6e-06 25.9 1.1 7.6e-06 25.9 1.1 3.4 2 1 2 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3341 PF11821.8 AAAP01003705.1_6 - 0.0028 17.3 0.1 0.12 12.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3341) HAMP PF00672.25 AAAP01003705.1_6 - 0.011 16.0 2.7 0.27 11.7 0.0 3.7 4 0 0 4 4 4 0 HAMP domain GCN5L1 PF06320.13 AAAP01003705.1_6 - 0.22 11.7 5.9 4 7.6 3.0 2.9 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Collagen_mid PF15984.5 AAAP01003705.1_6 - 0.36 10.6 8.7 0.72 9.6 8.7 1.5 1 0 0 1 1 1 0 Bacterial collagen, middle region FUSC PF04632.12 AAAP01003705.1_6 - 0.52 8.8 13.5 0.027 13.0 6.7 2.1 1 1 0 1 1 1 0 Fusaric acid resistance protein family Dppa2_A PF14049.6 AAAP01003705.1_6 - 0.58 10.3 6.4 1.3 9.2 6.4 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates UCR_UQCRX_QCR9 PF05365.12 AAAP01003705.1_6 - 0.74 9.8 4.2 0.39 10.7 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF948 PF06103.11 AAAP01003705.1_6 - 0.92 9.8 11.3 14 6.0 1.4 4.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) 4HB_MCP_1 PF12729.7 AAAP01003705.1_6 - 1.5 8.3 7.9 1.4 8.4 0.9 3.5 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction DUF1664 PF07889.12 AAAP01003705.1_6 - 4 7.5 9.4 0.89 9.6 2.6 3.2 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) LysR_substrate PF03466.20 AAAP01003706.1_2 - 0.015 14.7 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 LysR substrate binding domain Transposase_mut PF00872.18 AAAP01003706.1_3 - 3.8e-63 213.6 0.0 4.9e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AAAP01003706.1_3 - 1.3e-06 28.8 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_IS240 PF13610.6 AAAP01003706.1_3 - 0.16 12.2 0.0 0.57 10.4 0.0 1.8 1 1 1 2 2 2 0 DDE domain Epimerase_2 PF02350.19 AAAP01003707.1_2 - 6e-102 341.1 0.0 6.8e-102 340.9 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 AAAP01003707.1_2 - 0.0011 19.4 0.5 0.16 12.4 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain MGS PF02142.22 AAAP01003707.1_3 - 2.4e-27 95.0 0.0 3.3e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 MGS-like domain AICARFT_IMPCHas PF01808.18 AAAP01003707.1_3 - 0.00021 20.9 0.1 0.00029 20.4 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme AICARFT_IMPCHas PF01808.18 AAAP01003707.1_4 - 1.3e-102 343.3 0.1 1.5e-102 343.1 0.1 1.0 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme CW_binding_2 PF04122.12 AAAP01003707.1_4 - 0.37 11.5 12.3 1.4 9.6 0.5 3.2 2 1 1 3 3 3 0 Putative cell wall binding repeat 2 PMT_2 PF13231.6 AAAP01003707.1_5 - 0.013 15.7 25.3 0.13 12.5 18.2 2.8 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase RNA_pol_A_CTD PF03118.15 AAAP01003708.1_1 - 1.7e-25 88.6 1.8 1.7e-25 88.6 1.8 1.8 2 0 0 2 2 2 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 AAAP01003708.1_1 - 1.1e-09 37.6 0.0 3e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IDH PF03971.14 AAAP01003708.1_1 - 0.072 11.5 0.1 0.069 11.6 0.1 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase DUF2555 PF10742.9 AAAP01003708.1_1 - 0.089 12.6 0.0 2.8 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2555) MtaB PF12176.8 AAAP01003708.1_1 - 0.1 11.4 0.1 2.5 6.8 0.0 1.9 1 1 1 2 2 2 0 Methanol-cobalamin methyltransferase B subunit Ribosomal_L17 PF01196.19 AAAP01003708.1_2 - 2.4e-35 121.3 0.0 3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 TPR_19 PF14559.6 AAAP01003708.1_3 - 6.1e-12 45.9 0.0 0.00012 22.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Methyltransf_11 PF08241.12 AAAP01003708.1_3 - 7.1e-11 42.6 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003708.1_3 - 4.7e-10 40.0 0.0 1.2e-09 38.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003708.1_3 - 7.7e-10 38.8 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPR_2 PF07719.17 AAAP01003708.1_3 - 1e-08 34.6 0.2 0.46 10.7 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat Methyltransf_12 PF08242.12 AAAP01003708.1_3 - 3.7e-07 30.8 0.0 1e-06 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003708.1_3 - 8.5e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPR_14 PF13428.6 AAAP01003708.1_3 - 9.3e-07 29.2 2.0 1.5 9.9 0.0 5.6 3 2 3 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003708.1_3 - 4.5e-06 26.5 0.0 0.71 10.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003708.1_3 - 2.6e-05 24.4 0.5 2 8.8 0.0 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003708.1_3 - 9.4e-05 22.1 0.0 5.3 7.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003708.1_3 - 0.00022 21.7 0.2 13 6.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003708.1_3 - 0.00036 20.4 0.1 5.1 7.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat NodS PF05401.11 AAAP01003708.1_3 - 0.00046 19.9 0.0 0.0007 19.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) ANAPC3 PF12895.7 AAAP01003708.1_3 - 0.0014 18.8 0.0 0.26 11.5 0.0 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 AAAP01003708.1_3 - 0.0062 17.2 0.6 24 5.7 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003708.1_3 - 0.015 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003708.1_3 - 0.019 14.8 0.9 1.8 8.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PCMT PF01135.19 AAAP01003708.1_3 - 0.03 14.1 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 AAAP01003708.1_3 - 0.035 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPR_20 PF14561.6 AAAP01003708.1_3 - 0.038 14.3 0.1 0.092 13.1 0.0 1.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003708.1_3 - 0.052 13.9 0.0 9.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RrnaAD PF00398.20 AAAP01003708.1_3 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPR_4 PF07721.14 AAAP01003708.1_3 - 2.2 9.2 0.0 2.2 9.2 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat ATP12 PF07542.11 AAAP01003708.1_4 - 1.7e-36 125.2 0.0 3.2e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein AsmA_2 PF13502.6 AAAP01003708.1_5 - 7.1e-13 48.6 9.2 2.2e-10 40.5 0.6 4.3 3 1 0 4 4 4 2 AsmA-like C-terminal region AsmA PF05170.14 AAAP01003708.1_5 - 1.1e-11 44.3 0.0 2.5e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 AsmA family TENA_THI-4 PF03070.16 AAAP01003709.1_1 - 7.9e-53 179.4 0.0 8.9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Lactamase_B_2 PF12706.7 AAAP01003709.1_2 - 2.1e-46 158.0 0.0 2.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01003709.1_3 - 5.6e-25 88.5 2.4 7.8e-25 88.0 2.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01003709.1_3 - 0.0049 16.4 0.3 0.025 14.1 0.3 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Defensin_propep PF00879.18 AAAP01003709.1_3 - 0.082 13.2 0.6 0.19 12.0 0.6 1.6 1 0 0 1 1 1 0 Defensin propeptide SoxZ PF08770.11 AAAP01003709.1_4 - 3.3e-06 26.8 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ SBP_bac_3 PF00497.20 AAAP01003709.1_5 - 4.4e-28 98.3 0.0 4.3e-27 95.0 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Cytochrome_CBB3 PF13442.6 AAAP01003709.1_6 - 1.4e-13 50.9 0.0 2.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003709.1_6 - 8.1e-06 26.9 0.0 6.2e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome c Peripla_BP_6 PF13458.6 AAAP01003709.1_7 - 1.2e-12 48.2 5.1 1.2e-11 44.9 5.1 2.0 1 1 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01003709.1_7 - 1.1e-05 24.7 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DUF4883 PF16224.5 AAAP01003709.1_7 - 0.048 13.9 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) TetR_C_15 PF17918.1 AAAP01003709.1_7 - 0.37 11.6 3.8 0.22 12.3 0.9 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PALB2_WD40 PF16756.5 AAAP01003709.1_8 - 0.073 12.0 0.0 0.075 11.9 0.0 1.0 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PepSY_2 PF13670.6 AAAP01003709.1_8 - 0.11 12.5 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Patatin PF01734.22 AAAP01003710.1_1 - 2.3e-07 31.2 0.2 2.6e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase Thioesterase PF00975.20 AAAP01003710.1_2 - 4.2e-30 105.6 0.0 6.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 AAAP01003710.1_2 - 9.8e-12 45.1 0.1 2e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 AAAP01003710.1_2 - 1.5e-05 25.7 0.6 1.5e-05 25.7 0.6 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01003710.1_2 - 0.0004 19.7 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PS-DH PF14765.6 AAAP01003710.1_3 - 3e-59 200.7 0.1 5.5e-59 199.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 AAAP01003710.1_3 - 6.7e-57 192.3 2.4 1.2e-56 191.5 2.4 1.4 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 AAAP01003710.1_3 - 3.6e-40 138.4 0.4 5.3e-40 137.9 0.4 1.2 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.25 AAAP01003710.1_3 - 1.6e-06 27.7 0.1 3.6e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003710.1_3 - 1.9e-06 27.6 1.6 3.9e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 AAAP01003710.1_3 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Thiamine_BP PF01910.17 AAAP01003710.1_3 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine-binding protein Peptidase_M48 PF01435.18 AAAP01003711.1_1 - 1.8e-19 70.3 0.1 3.6e-19 69.3 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 AAAP01003711.1_1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Virul_fac_BrkB PF03631.15 AAAP01003711.1_2 - 6.9e-23 81.6 23.4 9.2e-23 81.2 23.4 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF4131 PF13567.6 AAAP01003711.1_3 - 0.0075 15.9 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF3787 PF12655.7 AAAP01003711.1_3 - 0.047 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) CusF_Ec PF11604.8 AAAP01003711.1_4 - 0.14 12.1 0.0 0.93 9.5 0.0 2.2 1 1 0 1 1 1 0 Copper binding periplasmic protein CusF DUF4131 PF13567.6 AAAP01003711.1_5 - 0.67 9.6 2.8 10 5.7 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) MCPsignal PF00015.21 AAAP01003712.1_1 - 6.6e-19 68.4 12.8 8.4e-19 68.0 8.8 2.3 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.12 AAAP01003712.1_1 - 0.00034 20.7 1.7 0.083 12.9 0.8 3.0 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellin_IN PF07196.13 AAAP01003712.1_1 - 0.017 15.3 3.5 0.34 11.1 0.0 3.3 3 0 0 3 3 3 0 Flagellin hook IN motif Metal_resist PF13801.6 AAAP01003712.1_1 - 0.031 14.5 0.7 0.031 14.5 0.7 2.7 2 1 0 2 2 2 0 Heavy-metal resistance DUF4994 PF16385.5 AAAP01003712.1_1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function STAS_2 PF13466.6 AAAP01003712.1_2 - 7.1e-14 51.9 1.4 9.2e-14 51.6 1.4 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003712.1_2 - 0.015 14.9 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 STAS domain Response_reg PF00072.24 AAAP01003712.1_3 - 9.8e-26 90.1 0.0 1.1e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF2189 PF09955.9 AAAP01003712.1_5 - 3.4e-21 75.8 4.9 6.6e-20 71.6 3.8 2.0 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2189) DUF1616 PF07760.11 AAAP01003712.1_5 - 0.091 12.1 0.5 0.11 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Phage_holin_3_6 PF07332.11 AAAP01003712.1_5 - 4.8 7.3 9.4 3.9 7.5 3.9 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ROS_MUCR PF05443.11 AAAP01003713.1_1 - 2.9e-44 150.1 0.0 3.2e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein Bac_DNA_binding PF00216.21 AAAP01003713.1_2 - 1.1e-32 112.0 0.1 1.3e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003713.1_2 - 4.9e-07 29.9 0.0 5.3e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 AAAP01003713.1_2 - 0.0085 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 DUF2267 PF10025.9 AAAP01003713.1_2 - 0.032 14.5 0.1 0.041 14.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) HU-CCDC81_euk_1 PF14908.6 AAAP01003713.1_2 - 0.05 13.8 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 AAAP01003713.1_2 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DDE_Tnp_IS1595 PF12762.7 AAAP01003713.1_4 - 1.3e-36 125.9 0.0 1.8e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Zn_Tnp_IS1595 PF12760.7 AAAP01003713.1_4 - 1.2e-14 54.0 2.2 2.3e-14 53.1 2.2 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Glyco_trans_2_3 PF13632.6 AAAP01003713.1_5 - 0.083 12.8 1.5 0.11 12.3 1.5 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF4389 PF14333.6 AAAP01003713.1_5 - 0.093 12.7 3.8 0.11 12.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Rax2 PF12768.7 AAAP01003713.1_5 - 0.11 11.9 0.8 0.11 12.0 0.8 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity YIEGIA PF14045.6 AAAP01003713.1_5 - 0.15 10.9 0.7 0.17 10.7 0.7 1.0 1 0 0 1 1 1 0 YIEGIA protein Hemerythrin PF01814.23 AAAP01003713.1_6 - 2.2e-09 38.0 1.9 2.5e-09 37.8 1.9 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HemY_N PF07219.13 AAAP01003713.1_7 - 0.1 12.8 1.4 0.19 12.0 1.4 1.4 1 0 0 1 1 1 0 HemY protein N-terminus EF-G-binding_N PF07299.11 AAAP01003713.1_8 - 0.13 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal PRIMA1 PF16101.5 AAAP01003713.1_8 - 0.37 10.8 1.5 0.59 10.2 1.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Response_reg PF00072.24 AAAP01003714.1_1 - 2.7e-18 66.1 0.0 6.2e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 AAAP01003714.1_1 - 1.2e-14 54.5 0.7 6.5e-14 52.1 0.0 2.4 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 AAAP01003714.1_1 - 2.9e-11 43.2 0.1 2.9e-11 43.2 0.1 4.0 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003714.1_1 - 3.9e-10 39.9 0.0 7.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003714.1_1 - 6.8e-09 35.7 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003714.1_1 - 0.012 15.6 0.1 0.058 13.4 0.1 2.2 1 0 0 1 1 1 0 PAS domain DUF1192 PF06698.11 AAAP01003714.1_1 - 1.8 8.7 8.2 5 7.3 8.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Response_reg PF00072.24 AAAP01003714.1_2 - 9.8e-47 157.8 0.2 2.3e-23 82.5 0.1 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003714.1_2 - 4.3e-23 81.9 0.1 3.4e-22 79.1 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003714.1_2 - 1.5e-11 44.1 0.0 1.5e-11 44.1 0.0 2.6 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003714.1_2 - 0.00096 19.0 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01003714.1_2 - 0.0018 18.1 0.0 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CtsR PF05848.11 AAAP01003714.1_2 - 0.079 12.9 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 CtsR N-terminal HTH domain CcdA PF07362.12 AAAP01003714.1_2 - 0.53 10.8 4.2 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA CheB_methylest PF01339.17 AAAP01003714.1_3 - 5.1e-51 172.8 0.1 1e-50 171.8 0.0 1.5 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AAAP01003714.1_3 - 5.2e-21 74.9 1.3 9.1e-21 74.1 0.3 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Response_reg PF00072.24 AAAP01003714.1_4 - 6.9e-23 80.9 0.1 1.3e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 AAAP01003714.1_4 - 1.8e-14 53.7 1.0 1.8e-14 53.7 1.0 2.6 2 2 0 2 2 2 1 Hpt domain HATPase_c PF02518.26 AAAP01003714.1_4 - 6.3e-14 52.4 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CheW PF01584.19 AAAP01003714.1_4 - 2.7e-13 49.8 0.6 5.5e-13 48.7 0.6 1.6 1 0 0 1 1 1 1 CheW-like domain TelA PF05816.11 AAAP01003714.1_4 - 0.009 15.1 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) HATPase_c_2 PF13581.6 AAAP01003714.1_4 - 0.032 14.2 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HEAT_PBS PF03130.16 AAAP01003714.1_4 - 1 10.2 5.1 3 8.8 0.8 3.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat MCPsignal PF00015.21 AAAP01003714.1_5 - 3.4e-07 30.2 7.0 3.4e-07 30.2 7.0 1.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain MiaE PF06175.11 AAAP01003714.1_5 - 0.011 15.3 0.6 0.013 15.1 0.6 1.1 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Dak2 PF02734.17 AAAP01003714.1_5 - 0.044 13.7 2.3 0.054 13.4 2.3 1.2 1 0 0 1 1 1 0 DAK2 domain Sec8_exocyst PF04048.14 AAAP01003714.1_5 - 0.06 13.2 8.1 0.081 12.8 6.0 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain FIVAR PF07554.13 AAAP01003714.1_5 - 0.16 12.8 5.6 0.18 12.6 1.0 2.5 2 1 0 2 2 2 0 FIVAR domain RmuC PF02646.16 AAAP01003714.1_5 - 0.2 10.7 8.9 0.023 13.8 4.6 1.6 2 0 0 2 2 2 0 RmuC family YpzG PF14139.6 AAAP01003714.1_5 - 0.25 11.5 5.1 2.3 8.4 0.2 2.6 2 0 0 2 2 2 0 YpzG-like protein DUF4200 PF13863.6 AAAP01003714.1_5 - 0.27 11.6 6.0 2.8 8.4 4.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MbeD_MobD PF04899.12 AAAP01003714.1_5 - 0.27 11.4 8.7 0.6 10.3 5.6 2.5 2 1 1 3 3 3 0 MbeD/MobD like Phage_GPO PF05929.11 AAAP01003714.1_5 - 0.38 10.3 7.9 0.43 10.2 7.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1825 PF08855.10 AAAP01003714.1_5 - 0.43 10.5 4.3 8.8 6.3 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) DUF948 PF06103.11 AAAP01003714.1_5 - 0.68 10.2 8.5 1.5 9.1 4.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AAAP01003714.1_5 - 1.1 9.4 8.4 3.4 7.8 8.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 AAAP01003714.1_5 - 2 8.1 12.9 1.1 8.9 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF2232 PF09991.9 AAAP01003714.1_5 - 8.4 5.5 5.2 9.6 5.3 0.5 2.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2232) dCache_2 PF08269.11 AAAP01003715.1_1 - 1.7e-11 43.8 0.0 1.9e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Cache domain sCache_2 PF17200.4 AAAP01003715.1_1 - 3.6e-10 39.9 0.0 4.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Single Cache domain 2 Cache_3-Cache_2 PF17201.4 AAAP01003715.1_1 - 0.0049 16.2 0.0 0.0054 16.0 0.0 1.0 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain WG_beta_rep PF14903.6 AAAP01003715.1_1 - 0.18 12.1 4.1 1.5 9.2 0.1 3.0 3 0 0 3 3 3 0 WG containing repeat EPSP_synthase PF00275.20 AAAP01003715.1_2 - 4.1e-99 332.1 6.6 5.2e-99 331.8 6.6 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DEC-1_N PF04625.13 AAAP01003715.1_3 - 0.0086 15.1 6.3 0.015 14.4 6.3 1.3 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF5525 PF17663.1 AAAP01003715.1_3 - 0.06 11.4 8.0 0.086 10.9 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) PTCRA PF15028.6 AAAP01003715.1_3 - 0.063 13.0 0.5 0.22 11.2 0.3 2.0 2 0 0 2 2 2 0 Pre-T-cell antigen receptor EF-hand_6 PF13405.6 AAAP01003715.1_3 - 0.07 13.1 0.0 8 6.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 AAAP01003715.1_3 - 0.12 12.0 0.1 8.1 6.2 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 AAAP01003715.1_3 - 0.12 11.9 3.4 0.74 9.4 0.4 2.6 2 0 0 2 2 2 0 EF hand ACC_epsilon PF13822.6 AAAP01003715.1_4 - 0.0071 17.0 1.1 0.011 16.4 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit TAT_signal PF10518.9 AAAP01003715.1_4 - 0.028 14.3 1.7 0.028 14.3 1.7 1.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence AAA_34 PF13872.6 AAAP01003715.1_4 - 0.22 10.4 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 MCPsignal PF00015.21 AAAP01003715.1_5 - 6.9e-32 110.6 28.8 6.9e-32 110.6 28.8 5.4 3 1 2 5 5 5 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003715.1_5 - 2.4e-07 31.0 1.4 3.1e-06 27.5 0.0 3.8 4 0 0 4 4 4 1 HAMP domain ADIP PF11559.8 AAAP01003715.1_5 - 0.012 15.7 2.8 0.012 15.7 2.8 4.0 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 AAAP01003715.1_5 - 0.16 12.0 25.1 0.079 13.0 4.2 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) ArsR PF09824.9 AAAP01003715.1_5 - 0.55 9.8 4.6 0.82 9.3 0.3 3.0 3 0 0 3 3 3 0 ArsR transcriptional regulator DUF4258 PF14076.6 AAAP01003716.1_1 - 0.015 15.7 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) HD_2 PF12917.7 AAAP01003716.1_2 - 2.4e-07 30.7 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD_3 PF13023.6 AAAP01003716.1_2 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003716.1_2 - 0.036 14.3 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 HD domain DUF5132 PF17195.4 AAAP01003716.1_3 - 0.045 13.8 0.4 0.068 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) RNase_T PF00929.24 AAAP01003716.1_4 - 3.1e-16 60.4 0.0 5.6e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AAAP01003716.1_4 - 0.019 14.9 2.5 0.12 12.3 0.2 2.8 2 2 1 3 3 3 0 3' exoribonuclease, RNase T-like DUF2384 PF09722.10 AAAP01003716.1_5 - 5.7e-08 32.7 0.0 9.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) HTH_3 PF01381.22 AAAP01003716.1_6 - 3.7e-12 46.1 0.0 1.2e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003716.1_6 - 6e-08 32.9 0.2 1.2e-07 31.9 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003716.1_6 - 5.6e-05 23.1 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003716.1_6 - 0.12 12.9 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PhaC_N PF07167.13 AAAP01003716.1_7 - 3.9e-09 36.4 0.1 1.4e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Hemerythrin PF01814.23 AAAP01003716.1_8 - 1.6e-11 45.0 0.9 2e-11 44.7 0.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_integrase PF00589.22 AAAP01003716.1_9 - 0.025 14.4 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Peripla_BP_6 PF13458.6 AAAP01003717.1_1 - 2.4e-21 76.8 2.0 2.7e-21 76.6 2.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003717.1_1 - 0.0014 17.7 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003717.1_1 - 0.015 14.4 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Nitroreductase PF00881.24 AAAP01003717.1_2 - 3.4e-32 111.8 0.0 4.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAAP01003717.1_2 - 0.0006 19.4 0.0 1.3 8.5 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase MM_CoA_mutase PF01642.22 AAAP01003717.1_3 - 6.3e-118 394.5 0.0 7.1e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase RWP-RK PF02042.15 AAAP01003717.1_3 - 0.00088 19.2 0.2 0.0068 16.4 0.0 2.5 2 0 0 2 2 2 1 RWP-RK domain B12-binding PF02310.19 AAAP01003717.1_4 - 9.1e-21 74.1 0.2 1.1e-20 73.9 0.2 1.1 1 0 0 1 1 1 1 B12 binding domain PGM_PMM_I PF02878.16 AAAP01003717.1_4 - 0.0087 15.8 0.1 0.016 14.9 0.1 1.5 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I TPP_enzyme_N PF02776.18 AAAP01003717.1_4 - 0.052 13.2 0.0 7.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF1847 PF08901.11 AAAP01003717.1_4 - 0.054 13.1 0.0 0.21 11.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1847) MeaB PF03308.16 AAAP01003717.1_5 - 1e-89 300.1 2.1 1.2e-89 299.8 2.1 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AAAP01003717.1_5 - 9.8e-07 28.5 0.1 1e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AAAP01003717.1_5 - 4.5e-06 26.5 0.2 1.1e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003717.1_5 - 8.8e-05 22.9 0.4 0.00044 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 AAAP01003717.1_5 - 9.4e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 AAAP01003717.1_5 - 0.00016 21.4 0.0 0.00044 19.9 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.23 AAAP01003717.1_5 - 0.0032 17.5 0.0 0.0043 17.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 AAAP01003717.1_5 - 0.0046 16.9 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_19 PF13245.6 AAAP01003717.1_5 - 0.015 15.6 0.1 0.028 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003717.1_5 - 0.016 15.7 0.0 0.047 14.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter MobB PF03205.14 AAAP01003717.1_5 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 AAAP01003717.1_5 - 0.018 14.8 0.0 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003717.1_5 - 0.026 14.6 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AAAP01003717.1_5 - 0.031 14.6 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003717.1_5 - 0.031 14.8 0.3 0.21 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AAAP01003717.1_5 - 0.037 13.8 0.2 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAAP01003717.1_5 - 0.041 14.0 0.3 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 AAAP01003717.1_5 - 0.056 12.3 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 AAAP01003717.1_5 - 0.06 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAAP01003717.1_5 - 0.06 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 AAAP01003717.1_5 - 0.066 12.9 0.2 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 AAAP01003717.1_5 - 0.094 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PIF1 PF05970.14 AAAP01003717.1_5 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.22 AAAP01003717.1_5 - 0.12 11.6 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 AAAP01003717.1_5 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AAAP01003717.1_5 - 0.12 12.0 1.3 0.4 10.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 AAAP01003717.1_5 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_PrkA PF08298.11 AAAP01003717.1_5 - 0.26 10.1 0.0 0.44 9.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain CheB_methylest PF01339.17 AAAP01003717.1_6 - 7.2e-60 201.6 0.0 1.2e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 CheB methylesterase CheR PF01739.18 AAAP01003717.1_6 - 1.4e-54 184.6 0.0 2.2e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain HATPase_c PF02518.26 AAAP01003717.1_6 - 1e-23 84.0 0.0 2.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003717.1_6 - 3.4e-17 62.2 0.0 3.4e-17 62.2 0.0 2.9 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 AAAP01003717.1_6 - 2.2e-15 57.1 0.2 1.5e-14 54.4 0.0 2.7 3 0 0 3 3 1 1 PAS domain CheR_N PF03705.15 AAAP01003717.1_6 - 1.3e-13 50.4 0.4 2.8e-13 49.4 0.4 1.6 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain PAS PF00989.25 AAAP01003717.1_6 - 0.00022 21.2 0.0 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AAAP01003717.1_6 - 0.00055 20.2 0.1 0.0045 17.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold KASH_CCD PF14662.6 AAAP01003717.1_6 - 0.00079 19.3 11.8 0.00079 19.3 11.8 2.6 3 0 0 3 3 2 1 Coiled-coil region of CCDC155 or KASH DUF16 PF01519.16 AAAP01003717.1_6 - 0.003 18.0 6.6 0.01 16.3 6.6 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF16 Spc7 PF08317.11 AAAP01003717.1_6 - 0.003 16.5 16.3 0.003 16.5 16.3 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF1664 PF07889.12 AAAP01003717.1_6 - 0.005 16.9 5.9 0.059 13.4 2.8 3.0 3 0 0 3 3 2 1 Protein of unknown function (DUF1664) PAS_8 PF13188.7 AAAP01003717.1_6 - 0.009 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain Fez1 PF06818.15 AAAP01003717.1_6 - 0.014 15.9 10.9 0.024 15.1 7.4 2.3 2 0 0 2 2 2 0 Fez1 APG17 PF04108.12 AAAP01003717.1_6 - 0.035 13.2 8.9 0.5 9.4 6.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF745 PF05335.13 AAAP01003717.1_6 - 0.049 13.3 18.2 0.4 10.4 13.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Golgin_A5 PF09787.9 AAAP01003717.1_6 - 0.055 12.9 19.9 0.013 15.0 14.5 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 OmpH PF03938.14 AAAP01003717.1_6 - 0.071 13.4 15.4 0.19 12.0 11.3 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MscS_porin PF12795.7 AAAP01003717.1_6 - 0.074 12.6 25.9 0.017 14.7 18.7 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Syntaxin-6_N PF09177.11 AAAP01003717.1_6 - 0.079 13.5 15.3 6.3 7.4 11.0 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Methyltransf_12 PF08242.12 AAAP01003717.1_6 - 0.081 13.7 0.1 0.48 11.2 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain HATPase_c_3 PF13589.6 AAAP01003717.1_6 - 0.081 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WEMBL PF05701.11 AAAP01003717.1_6 - 0.082 11.6 17.4 0.022 13.5 11.8 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light HPTransfase PF10090.9 AAAP01003717.1_6 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain IFT57 PF10498.9 AAAP01003717.1_6 - 0.11 11.4 16.3 0.007 15.4 10.8 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 PCRF PF03462.18 AAAP01003717.1_6 - 0.14 12.0 15.1 1.5 8.7 0.0 3.3 3 0 0 3 3 3 0 PCRF domain Fusion_gly PF00523.18 AAAP01003717.1_6 - 0.14 10.3 6.4 0.48 8.6 2.3 2.3 1 1 1 2 2 2 0 Fusion glycoprotein F0 CENP-F_leu_zip PF10473.9 AAAP01003717.1_6 - 0.18 11.8 26.7 0.048 13.7 21.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 AAAP01003717.1_6 - 0.19 9.8 13.2 0.0033 15.7 6.2 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF812 PF05667.11 AAAP01003717.1_6 - 0.19 10.5 8.4 0.38 9.6 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.8 AAAP01003717.1_6 - 0.23 10.8 13.8 0.49 9.7 9.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Tropomyosin PF00261.20 AAAP01003717.1_6 - 0.33 10.3 22.3 0.15 11.4 15.2 2.3 2 0 0 2 2 2 0 Tropomyosin THOC7 PF05615.13 AAAP01003717.1_6 - 0.34 11.2 12.2 0.054 13.8 6.6 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 LMBR1 PF04791.16 AAAP01003717.1_6 - 0.34 9.7 0.6 0.56 9.1 0.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.9 AAAP01003717.1_6 - 0.42 11.3 7.6 0.3 11.8 3.5 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.9 AAAP01003717.1_6 - 0.6 9.1 9.6 1.8 7.6 9.6 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 AAAP01003717.1_6 - 0.62 9.5 19.6 0.19 11.1 14.5 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MCC-bdg_PDZ PF10506.9 AAAP01003717.1_6 - 0.64 10.1 10.8 5.9 7.0 2.5 3.2 2 1 1 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Sec8_exocyst PF04048.14 AAAP01003717.1_6 - 0.73 9.7 8.6 0.16 11.9 3.9 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4071 PF13281.6 AAAP01003717.1_6 - 0.86 8.6 4.1 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) 5_nucleotid PF05761.14 AAAP01003717.1_6 - 0.98 8.2 5.7 0.41 9.5 2.1 1.9 2 0 0 2 2 2 0 5' nucleotidase family Not3 PF04065.15 AAAP01003717.1_6 - 1 8.8 12.0 0.32 10.4 5.9 2.7 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component ATG16 PF08614.11 AAAP01003717.1_6 - 1.1 9.5 22.6 0.063 13.5 15.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DLP_helical PF18709.1 AAAP01003717.1_6 - 1.6 7.9 9.0 0.87 8.7 3.5 2.5 2 0 0 2 2 2 0 Dynamin-like helical domain RasGAP_C PF03836.15 AAAP01003717.1_6 - 1.7 8.8 9.6 1.3 9.2 6.1 2.3 2 0 0 2 2 2 0 RasGAP C-terminus Jnk-SapK_ap_N PF09744.9 AAAP01003717.1_6 - 2 8.7 24.7 28 4.9 19.6 3.2 3 1 0 3 3 2 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 AAAP01003717.1_6 - 2.3 8.3 16.3 0.14 12.3 10.5 1.9 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 AAAP01003717.1_6 - 2.7 7.2 15.1 0.55 9.5 10.9 1.8 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase CheZ PF04344.13 AAAP01003717.1_6 - 2.7 7.8 9.3 20 5.1 6.5 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ HAUS-augmin3 PF14932.6 AAAP01003717.1_6 - 3.1 7.3 18.2 0.22 11.1 12.0 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3584 PF12128.8 AAAP01003717.1_6 - 3.2 5.2 18.0 0.43 8.0 12.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 AAAP01003717.1_6 - 3.2 6.3 10.2 0.32 9.6 5.3 1.6 2 0 0 2 2 2 0 AAA domain FapA PF03961.13 AAAP01003717.1_6 - 3.2 6.2 9.9 0.22 10.1 4.4 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 AAAP01003717.1_6 - 3.7 7.6 27.8 0.26 11.4 19.7 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 AAAP01003717.1_6 - 3.9 6.2 20.7 0.08 11.8 9.7 2.4 3 0 0 3 3 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FmiP_Thoc5 PF09766.9 AAAP01003717.1_6 - 4.2 6.6 13.5 56 2.9 0.0 2.3 2 1 0 2 2 2 0 Fms-interacting protein/Thoc5 UPF0231 PF06062.11 AAAP01003717.1_6 - 4.3 7.6 7.2 11 6.3 7.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) Snapin_Pallidin PF14712.6 AAAP01003717.1_6 - 5.2 7.6 19.6 6.1 7.3 0.4 3.0 3 0 0 3 3 2 0 Snapin/Pallidin DUF4201 PF13870.6 AAAP01003717.1_6 - 7.6 6.2 17.2 1.8 8.2 12.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) KxDL PF10241.9 AAAP01003717.1_6 - 8.4 6.8 15.6 3.9 7.8 3.2 3.6 2 1 1 3 3 3 0 Uncharacterized conserved protein Rootletin PF15035.6 AAAP01003717.1_6 - 8.8 6.3 16.2 0.31 11.0 9.2 2.0 2 0 0 2 2 1 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 AAAP01003717.1_6 - 9.5 5.5 12.5 34 3.6 12.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HATPase_c PF02518.26 AAAP01003717.1_7 - 4.1e-25 88.5 0.0 1e-24 87.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003717.1_7 - 1e-20 74.0 0.1 7.3e-09 35.9 0.0 3.8 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 AAAP01003717.1_7 - 5.5e-11 42.3 3.7 1.3e-09 37.9 0.1 2.9 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003717.1_7 - 7.8e-10 38.9 0.0 0.0027 17.9 0.0 3.7 4 0 0 4 4 4 3 PAS domain PAS_8 PF13188.7 AAAP01003717.1_7 - 3.1e-09 36.6 0.0 0.31 11.1 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AAAP01003717.1_7 - 2.7e-07 30.6 0.0 0.0022 18.0 0.0 4.1 3 1 0 3 3 3 1 PAS fold DUF4407 PF14362.6 AAAP01003717.1_7 - 0.011 15.1 1.3 0.021 14.2 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HATPase_c_5 PF14501.6 AAAP01003717.1_7 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 GHKL domain BLOC1_2 PF10046.9 AAAP01003717.1_7 - 0.081 13.2 5.5 0.59 10.5 3.6 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 AAAP01003717.1_7 - 0.13 12.4 10.7 0.075 13.2 7.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 AAAP01003717.1_7 - 0.22 10.4 6.1 2.5 6.9 6.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 AAAP01003717.1_7 - 0.24 8.9 4.5 0.39 8.2 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 AAAP01003717.1_7 - 0.38 10.8 2.0 0.91 9.6 2.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 AAAP01003717.1_7 - 1 9.8 3.0 31 5.0 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) YlqD PF11068.8 AAAP01003717.1_7 - 1.4 9.3 8.3 3.6 8.0 8.3 1.6 1 0 0 1 1 1 0 YlqD protein OmpH PF03938.14 AAAP01003717.1_7 - 1.4 9.2 9.5 0.087 13.2 2.7 2.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) YabA PF06156.13 AAAP01003717.1_7 - 1.9 9.2 4.2 2 9.1 2.5 1.9 2 0 0 2 2 2 0 Initiation control protein YabA DNA_pol3_alpha PF07733.12 AAAP01003718.1_1 - 1.4e-100 336.2 0.0 2.4e-100 335.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AAAP01003718.1_1 - 1.8e-65 219.3 0.0 3e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain HHH_6 PF14579.6 AAAP01003718.1_1 - 3.4e-26 91.3 0.1 1.2e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif PHP PF02811.19 AAAP01003718.1_1 - 7.9e-24 84.8 0.0 1.6e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 PHP domain tRNA_anti-codon PF01336.25 AAAP01003718.1_1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF655 PF04919.12 AAAP01003718.1_1 - 0.083 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF655) LEA_2 PF03168.13 AAAP01003718.1_2 - 3.5e-16 59.6 0.1 7.1e-16 58.6 0.0 1.5 2 0 0 2 2 2 1 Late embryogenesis abundant protein Glyco_hydro_17 PF00332.18 AAAP01003718.1_3 - 1.9e-05 24.4 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltransf_21 PF05050.12 AAAP01003718.1_4 - 9.9e-12 45.2 0.0 2.1e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain Pentapeptide PF00805.22 AAAP01003718.1_5 - 1.5e-27 94.8 20.2 2.5e-11 43.0 1.0 4.0 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAAP01003718.1_5 - 1.5e-14 53.9 0.0 8.6e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AAAP01003718.1_5 - 1.2e-10 41.3 0.1 0.00014 21.9 0.3 3.1 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) CfAFP PF05264.11 AAAP01003718.1_5 - 0.062 13.3 0.0 0.53 10.3 0.0 2.1 1 1 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) ALAD PF00490.21 AAAP01003718.1_6 - 4.9e-139 462.9 0.1 5.6e-139 462.7 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Se-cys_synth_N PF12390.8 AAAP01003718.1_6 - 0.12 12.6 0.4 0.12 12.6 0.4 3.4 5 0 0 5 5 5 0 Selenocysteine synthase N terminal Cys_Met_Meta_PP PF01053.20 AAAP01003718.1_7 - 1e-14 53.9 0.0 1.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.28 AAAP01003719.1_1 - 7.8e-25 87.3 0.0 8.8e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 AAAP01003719.1_2 - 3.3e-08 34.2 0.0 5.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003719.1_2 - 0.00028 20.8 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 AAAP01003719.1_2 - 0.016 15.5 0.2 0.59 10.4 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 AAAP01003719.1_3 - 1.1e-24 87.5 0.0 1.5e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01003719.1_3 - 7.3e-10 38.5 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAAP01003719.1_3 - 5.2e-05 23.8 0.0 7.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01003719.1_3 - 0.0022 17.8 1.9 0.0071 16.2 0.3 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01003719.1_3 - 0.0023 18.2 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01003719.1_3 - 0.0086 16.5 0.2 0.16 12.4 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AAAP01003719.1_3 - 0.0096 15.6 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 AAAP01003719.1_3 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01003719.1_3 - 0.014 15.1 0.4 0.046 13.4 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003719.1_3 - 0.024 15.0 0.1 0.052 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01003719.1_3 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 AAAP01003719.1_3 - 0.029 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 AAAP01003719.1_3 - 0.03 13.9 7.2 0.46 10.0 0.0 2.7 3 1 0 3 3 2 0 AAA domain KdpD PF02702.17 AAAP01003719.1_3 - 0.036 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain SMC_N PF02463.19 AAAP01003719.1_3 - 0.058 12.8 0.1 0.74 9.2 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01003719.1_3 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 AAAP01003719.1_3 - 0.17 11.9 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 AAAP01003719.1_3 - 0.17 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain BPD_transp_2 PF02653.16 AAAP01003719.1_4 - 1e-32 113.4 34.6 1.4e-32 112.9 34.6 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01003719.1_5 - 1.5e-40 139.1 36.3 1.8e-40 138.9 36.3 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Peripla_BP_6 PF13458.6 AAAP01003719.1_6 - 7.8e-45 154.0 0.1 9.5e-45 153.7 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003719.1_6 - 3.7e-07 29.5 0.0 2.7e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003719.1_6 - 2.4e-06 26.9 0.0 5.7e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region LppC PF04348.13 AAAP01003719.1_6 - 0.069 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 LppC putative lipoprotein SAICAR_synt PF01259.18 AAAP01003719.1_7 - 3.4e-78 262.7 0.0 4.3e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase CBS PF00571.28 AAAP01003719.1_8 - 1.5e-19 70.2 0.2 2.4e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 CBS domain RadC PF04002.15 AAAP01003719.1_9 - 9.9e-43 145.0 0.0 1.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AAAP01003719.1_9 - 8.6e-05 22.3 0.1 0.00011 22.0 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Flg_bbr_C PF06429.13 AAAP01003720.1_1 - 1.1e-07 31.9 0.0 1.2e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Acetyltransf_1 PF00583.25 AAAP01003720.1_2 - 5.3e-12 46.0 0.0 2e-11 44.2 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003720.1_2 - 4.8e-08 33.3 0.0 1.2e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003720.1_2 - 3.4e-07 30.2 0.0 8.9e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003720.1_2 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAAP01003720.1_2 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAAP01003720.1_2 - 0.059 13.4 0.0 8.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MerT PF02411.15 AAAP01003720.1_2 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 MerT mercuric transport protein Cytochrome_CBB3 PF13442.6 AAAP01003720.1_6 - 2.9e-09 37.1 0.1 7.5e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003720.1_6 - 0.00017 22.6 0.1 0.0007 20.7 0.1 2.0 1 1 1 2 2 2 1 Cytochrome c VirB3 PF05101.13 AAAP01003720.1_6 - 0.11 12.7 0.8 0.19 11.9 0.8 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Polysacc_synt_3 PF13440.6 AAAP01003720.1_8 - 0.42 9.8 14.0 0.16 11.2 5.1 2.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein OMP_b-brl PF13505.6 AAAP01003720.1_9 - 2.5e-17 63.6 2.1 3.1e-17 63.3 2.1 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 AAAP01003720.1_9 - 3.9e-06 27.0 1.0 5.6e-05 23.3 0.5 2.6 1 1 1 2 2 2 1 Opacity family porin protein OmpA_membrane PF01389.17 AAAP01003720.1_9 - 0.00022 21.0 1.1 0.00075 19.3 1.0 2.1 1 1 0 1 1 1 1 OmpA-like transmembrane domain Porin_2 PF02530.14 AAAP01003720.1_9 - 0.0017 17.7 2.3 0.0021 17.4 1.8 1.3 1 1 0 1 1 1 1 Porin subfamily Surface_Ag_2 PF01617.17 AAAP01003720.1_9 - 0.0025 17.3 0.0 0.0075 15.7 0.0 1.6 1 1 0 1 1 1 1 Surface antigen DUF2490 PF10677.9 AAAP01003720.1_9 - 0.0051 16.8 0.1 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2490) PagL PF09411.10 AAAP01003720.1_9 - 0.0067 16.6 0.4 0.022 14.9 0.4 1.9 1 1 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) OMP_b-brl_2 PF13568.6 AAAP01003720.1_9 - 0.017 15.2 1.3 0.067 13.2 1.1 2.1 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain ATPase_gene1 PF09527.10 AAAP01003720.1_9 - 1.3 9.2 4.3 9.8 6.4 0.1 2.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter OEP PF02321.18 AAAP01003720.1_11 - 5.8e-11 42.5 2.3 5.8e-11 42.5 2.3 3.3 2 1 0 3 3 3 2 Outer membrane efflux protein Cu-oxidase_3 PF07732.15 AAAP01003720.1_12 - 6e-25 87.6 0.0 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase SQS_PSY PF00494.19 AAAP01003721.1_1 - 9.5e-49 166.2 0.2 1.3e-48 165.9 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Aldedh PF00171.22 AAAP01003721.1_2 - 1.2e-109 366.9 0.0 1.7e-109 366.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 AAAP01003721.1_2 - 6e-91 305.0 0.0 8.7e-91 304.5 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 AAAP01003721.1_2 - 1.9e-42 144.3 0.0 4.5e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 AAAP01003721.1_2 - 0.0042 17.3 4.5 0.0042 17.3 4.5 3.1 2 0 0 2 2 2 1 Proline utilization A proline dehydrogenase N-terminal domain PEP-utilisers_N PF05524.13 AAAP01003721.1_2 - 0.11 12.6 1.5 0.41 10.8 1.5 1.9 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF2892 PF11127.8 AAAP01003721.1_3 - 1e-17 63.9 4.3 1.1e-17 63.8 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) ACT_6 PF13740.6 AAAP01003721.1_4 - 3.1e-11 43.1 0.1 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AAAP01003721.1_4 - 3.1e-10 39.6 1.6 6.7e-06 25.8 0.1 2.5 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 AAAP01003721.1_4 - 7.5e-08 32.9 0.0 2.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 ACT domain DUF5455 PF17537.2 AAAP01003721.1_4 - 0.0065 16.9 0.0 4.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5455) Cytochrome_CBB3 PF13442.6 AAAP01003721.1_5 - 1.1e-12 48.1 0.1 1.8e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003721.1_5 - 1.3e-09 39.1 0.0 2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Methyltransf_24 PF13578.6 AAAP01003721.1_6 - 9.9e-09 36.2 0.0 2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 AAAP01003721.1_6 - 0.089 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Glyco_transf_41 PF13844.6 AAAP01003721.1_7 - 1.1e-43 149.4 0.0 1.8e-41 142.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 41 CbiC PF02570.15 AAAP01003721.1_7 - 0.009 15.7 0.6 0.03 14.0 0.1 1.9 2 0 0 2 2 2 1 Precorrin-8X methylmutase DEC-1_N PF04625.13 AAAP01003722.1_1 - 1 8.3 8.2 1.1 8.3 8.2 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MlaD PF02470.20 AAAP01003722.1_2 - 5.6e-05 23.4 0.0 8.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 AAAP01003722.1_3 - 2.4e-07 30.9 0.1 3e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 AAAP01003722.1_4 - 7.7e-18 64.6 0.1 1.8e-17 63.4 0.2 1.6 2 0 0 2 2 2 1 MlaD protein NDUFA12 PF05071.16 AAAP01003722.1_5 - 1.6e-25 89.7 2.7 1.9e-25 89.5 2.7 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribonuc_red_lgC PF02867.15 AAAP01003722.1_6 - 9.5e-125 417.1 0.0 1.4e-106 357.1 0.0 2.3 2 0 0 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_2_N PF08471.10 AAAP01003722.1_6 - 2.9e-42 142.9 0.1 1.3e-41 140.8 0.0 2.2 2 0 0 2 2 2 1 Class II vitamin B12-dependent ribonucleotide reductase Transcrip_reg PF01709.20 AAAP01003722.1_6 - 0.0017 17.8 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator RNA_POL_M_15KD PF02150.16 AAAP01003722.1_6 - 2.4 8.1 5.0 6.7 6.7 5.0 1.7 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit GGDEF PF00990.21 AAAP01003722.1_7 - 0.15 11.8 0.0 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 Diguanylate cyclase, GGDEF domain Sigma70_r3 PF04539.16 AAAP01003723.1_1 - 8.8e-33 112.2 4.0 5.5e-30 103.3 0.7 3.0 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 AAAP01003723.1_1 - 3.6e-22 77.9 1.2 7.5e-22 76.9 0.3 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAAP01003723.1_1 - 1.8e-20 72.2 7.3 6.7e-19 67.2 1.1 2.9 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_ner PF04546.13 AAAP01003723.1_1 - 1.9e-14 54.1 2.5 2.3e-14 53.8 0.0 2.4 3 1 1 4 4 4 1 Sigma-70, non-essential region HTH_IclR PF09339.10 AAAP01003723.1_1 - 0.014 15.2 0.1 1.9 8.4 0.0 3.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_25 PF13413.6 AAAP01003723.1_1 - 0.017 14.9 1.7 8.9 6.3 0.0 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_15 PF12324.8 AAAP01003723.1_1 - 0.064 13.2 0.4 0.91 9.5 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase MarR_2 PF12802.7 AAAP01003723.1_1 - 0.11 12.5 0.5 2.6 8.0 0.0 2.8 3 0 0 3 3 3 0 MarR family HATPase_c PF02518.26 AAAP01003723.1_2 - 1.1e-20 74.2 0.0 1.9e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003723.1_2 - 1.6e-09 37.7 0.0 3.5e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01003723.1_2 - 1.2e-08 35.1 0.0 9.2e-07 29.1 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 AAAP01003723.1_2 - 1.6e-08 34.7 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain dCache_1 PF02743.18 AAAP01003723.1_2 - 1.8e-08 34.5 0.0 3.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Cache domain PAS_8 PF13188.7 AAAP01003723.1_2 - 1.3e-07 31.4 0.0 4.2e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003723.1_2 - 6.5e-07 29.3 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003723.1_2 - 0.0019 18.4 0.0 0.02 15.1 0.0 2.6 3 0 0 3 3 3 1 PAS fold FlbT PF07378.11 AAAP01003723.1_3 - 3.9e-39 133.6 0.0 4.6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FlbT DSBA PF01323.20 AAAP01003723.1_4 - 3.5e-32 111.8 0.0 4e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short_C2 PF13561.6 AAAP01003723.1_5 - 1.1e-26 93.9 1.9 1.3e-26 93.6 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003723.1_5 - 1.7e-26 92.9 0.1 2.4e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003723.1_5 - 5e-05 23.3 2.1 0.0001 22.3 2.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003723.1_5 - 0.00033 20.2 0.1 0.00048 19.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003723.1_5 - 0.028 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ribonuc_L-PSP PF01042.21 AAAP01003723.1_6 - 2.2e-24 85.8 0.1 2.4e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1491 PF07372.12 AAAP01003723.1_7 - 6.8e-13 48.9 0.1 7.5e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1491) cNMP_binding PF00027.29 AAAP01003723.1_8 - 7.9e-21 73.9 0.0 1.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 AAAP01003723.1_8 - 2.8e-16 59.5 3.9 4.3e-16 58.9 3.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AAAP01003723.1_8 - 4.2e-16 58.7 3.3 4.2e-16 58.7 3.3 2.5 2 0 0 2 2 2 1 Ion channel AmpE PF17113.5 AAAP01003723.1_8 - 0.018 14.4 1.1 0.036 13.4 0.6 1.8 1 1 1 2 2 2 0 Regulatory signalling modulator protein AmpE DUF2937 PF11157.8 AAAP01003723.1_8 - 3.3 7.4 6.0 1.4 8.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Exo_endo_phos PF03372.23 AAAP01003723.1_9 - 2.4e-10 40.3 0.0 1.9e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SpoU_methylase PF00588.19 AAAP01003724.1_1 - 4.4e-19 69.0 0.0 4.9e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Rotamase_3 PF13616.6 AAAP01003724.1_2 - 4.5e-30 104.6 0.0 4.8e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAAP01003724.1_2 - 4.9e-30 104.3 0.0 5.5e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAAP01003724.1_2 - 1.8e-07 32.0 0.0 2.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain PPK2 PF03976.14 AAAP01003724.1_3 - 3.6e-103 344.0 0.5 4.3e-103 343.7 0.5 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) zf-NADH-PPase PF09297.11 AAAP01003724.1_4 - 0.0021 17.7 0.7 0.0021 17.7 0.7 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Yippee-Mis18 PF03226.14 AAAP01003724.1_4 - 0.01 16.0 0.0 0.022 15.0 0.0 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF983 PF06170.12 AAAP01003724.1_4 - 0.036 14.5 0.3 0.31 11.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF983) PseudoU_synth_2 PF00849.22 AAAP01003724.1_5 - 1.1e-15 58.1 0.0 9.7e-15 55.0 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAAP01003724.1_5 - 0.016 14.9 0.1 0.09 12.5 0.1 2.2 1 1 1 2 2 2 0 S4 domain MTS PF05175.14 AAAP01003724.1_6 - 1.6e-42 144.9 0.0 2.6e-41 141.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AAAP01003724.1_6 - 1.6e-06 28.0 0.0 4.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003724.1_6 - 4.2e-06 27.4 0.0 8.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003724.1_6 - 7.3e-05 22.7 0.0 0.058 13.2 0.0 2.8 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003724.1_6 - 0.0028 18.4 0.0 0.017 15.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003724.1_6 - 0.011 16.4 0.0 0.95 10.2 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.26 AAAP01003724.1_6 - 0.03 14.3 0.0 0.75 9.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HEAT_2 PF13646.6 AAAP01003724.1_7 - 0.12 12.8 1.8 0.44 11.0 1.7 2.0 1 1 0 1 1 1 0 HEAT repeats 2Fe-2S_thioredx PF01257.19 AAAP01003724.1_8 - 0.00042 20.2 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 AAAP01003724.1_8 - 0.019 15.4 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) DUF4170 PF13773.6 AAAP01003724.1_9 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) DUF4170 PF13773.6 AAAP01003724.1_10 - 3.1e-07 30.4 0.0 5.5e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4170) CD52 PF15116.6 AAAP01003724.1_11 - 0.082 12.9 4.4 0.74 9.9 2.2 2.3 2 0 0 2 2 2 0 CAMPATH-1 antigen GIDA PF01134.22 AAAP01003724.1_12 - 1.4e-60 205.5 0.0 1.8e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 AAAP01003724.1_12 - 0.00026 20.7 0.4 0.0036 16.9 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003724.1_12 - 0.00044 19.6 0.0 0.00073 18.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01003724.1_12 - 0.0042 16.2 0.3 0.0056 15.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003724.1_12 - 0.0078 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AAAP01003724.1_12 - 0.065 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 AAAP01003724.1_12 - 0.085 12.2 0.2 0.089 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 AAAP01003724.1_12 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 AAAP01003724.1_13 - 2.1e-40 139.0 0.0 2.3e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A Antirestrict PF03230.13 AAAP01003724.1_13 - 0.11 12.5 0.0 4.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Antirestriction protein TPR_16 PF13432.6 AAAP01003725.1_1 - 1.9e-07 31.6 0.7 2.9e-07 31.0 0.7 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003725.1_1 - 7.1e-06 25.8 0.3 0.00021 21.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003725.1_1 - 5.2e-05 23.7 0.1 8.8e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003725.1_1 - 5.5e-05 23.4 1.1 0.00015 22.0 1.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003725.1_1 - 0.00031 21.3 0.4 0.41 11.6 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003725.1_1 - 0.00097 19.2 0.4 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003725.1_1 - 0.0015 18.8 0.1 0.0089 16.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003725.1_1 - 0.0024 17.6 0.5 0.021 14.6 0.2 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003725.1_1 - 0.0051 16.9 0.2 0.031 14.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat HemY_N PF07219.13 AAAP01003725.1_1 - 0.0052 17.0 0.1 0.032 14.4 0.1 2.1 1 1 1 2 2 2 1 HemY protein N-terminus TPR_10 PF13374.6 AAAP01003725.1_1 - 0.0053 16.6 3.5 0.094 12.6 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003725.1_1 - 0.0093 16.5 2.5 1.5 9.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003725.1_1 - 0.0097 16.5 0.9 0.0097 16.5 0.9 2.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003725.1_1 - 0.053 13.6 0.5 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003725.1_1 - 0.065 13.5 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4919 PF16266.5 AAAP01003725.1_1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) LPAM_2 PF13627.6 AAAP01003725.1_1 - 0.9 9.5 4.2 1.8 8.5 4.2 1.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site CHAD PF05235.14 AAAP01003725.1_2 - 2.6e-53 181.4 2.4 3.5e-53 180.9 2.4 1.2 1 0 0 1 1 1 1 CHAD domain CYTH PF01928.21 AAAP01003725.1_2 - 2.4e-23 83.0 0.0 7.5e-23 81.4 0.0 1.8 2 0 0 2 2 2 1 CYTH domain EAL PF00563.20 AAAP01003725.1_3 - 6.8e-73 245.1 0.0 1e-72 244.5 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003725.1_3 - 1.3e-44 151.7 0.0 2.1e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003725.1_3 - 4.3e-35 120.1 0.0 3.9e-11 43.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AAAP01003725.1_3 - 3.4e-27 94.9 0.8 5.2e-12 46.0 0.1 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAAP01003725.1_3 - 5.3e-27 94.1 0.0 4.7e-12 45.9 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 AAAP01003725.1_3 - 4.5e-16 58.9 0.1 1.6e-06 28.3 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AAAP01003725.1_3 - 1.6e-14 53.5 0.0 4.5e-05 23.4 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS_10 PF13596.6 AAAP01003725.1_3 - 0.076 13.6 0.0 0.6 10.7 0.0 2.3 2 0 0 2 2 2 0 PAS domain DUF4169 PF13770.6 AAAP01003725.1_4 - 6e-19 68.1 14.0 6.6e-19 67.9 14.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4169) DUF1682 PF07946.14 AAAP01003725.1_4 - 6.2 5.9 9.6 6.9 5.8 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ammonium_transp PF00909.21 AAAP01003725.1_5 - 2e-85 286.9 40.1 2.3e-85 286.7 40.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HATPase_c PF02518.26 AAAP01003725.1_6 - 0.021 15.3 0.0 0.023 15.2 0.0 1.0 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01003725.1_7 - 5.1e-17 62.4 0.0 7.4e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01003725.1_7 - 0.052 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003725.1_7 - 0.091 12.7 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain AAA_19 PF13245.6 AAAP01003726.1_2 - 5.2e-09 36.6 0.0 6.7e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 AAAP01003726.1_2 - 8e-08 32.0 0.0 2.2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain NERD PF08378.11 AAAP01003726.1_2 - 1.4e-06 28.7 0.0 3.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Nuclease-related domain AAA_12 PF13087.6 AAAP01003726.1_2 - 0.0033 17.1 0.1 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AAAP01003726.1_2 - 0.0048 17.2 0.0 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AAAP01003726.1_2 - 0.0055 16.0 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AAAP01003726.1_2 - 0.007 16.1 0.0 5 6.8 0.0 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AAAP01003726.1_2 - 0.022 14.5 0.0 0.34 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AAAP01003726.1_2 - 0.033 14.6 0.1 0.16 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 AAAP01003726.1_2 - 0.14 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 AAAP01003726.1_2 - 0.14 12.5 0.2 22 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAAP01003726.1_2 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003726.1_2 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01003726.1_2 - 0.17 11.3 0.0 0.93 8.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 AAAP01003726.1_2 - 0.24 11.4 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit 5-nucleotidase PF06189.12 AAAP01003726.1_3 - 2.6e-96 321.7 0.0 3.5e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase WYL PF13280.6 AAAP01003726.1_4 - 8.5e-27 94.3 0.1 1.2e-26 93.8 0.1 1.1 1 0 0 1 1 1 1 WYL domain HTH_23 PF13384.6 AAAP01003726.1_5 - 0.11 12.4 0.1 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 Homeodomain-like domain DUF2779 PF11074.8 AAAP01003726.1_6 - 1.9e-35 122.1 0.0 3.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) Cas_Cas4 PF01930.17 AAAP01003726.1_6 - 0.82 9.8 2.9 16 5.6 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function DUF83 Abhydrolase_1 PF00561.20 AAAP01003726.1_8 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold KdpA PF03814.15 AAAP01003727.1_1 - 1.7e-173 577.8 19.6 2.1e-173 577.5 19.6 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit DUF4131 PF13567.6 AAAP01003727.1_1 - 0.042 13.5 13.6 0.29 10.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2613 PF11021.8 AAAP01003727.1_1 - 3.3 7.9 9.1 4.5 7.5 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Potass_KdpF PF09604.10 AAAP01003727.1_2 - 6.1e-05 22.9 0.5 8.5e-05 22.4 0.5 1.3 1 1 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) CorA PF01544.18 AAAP01003727.1_3 - 5.2e-36 124.5 0.3 1.5e-35 123.0 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MgtE_N PF03448.17 AAAP01003727.1_3 - 0.0019 18.7 3.6 0.0023 18.5 0.1 2.6 3 0 0 3 3 3 1 MgtE intracellular N domain DUF87 PF01935.17 AAAP01003727.1_4 - 4.3e-09 36.8 0.0 6.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 AAAP01003727.1_4 - 6.9e-07 29.6 0.0 1.6e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003727.1_4 - 4.3e-06 27.2 0.2 4.3e-06 27.2 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 AAAP01003727.1_4 - 5.9e-05 22.1 0.0 0.01 14.8 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AAAP01003727.1_4 - 0.00033 20.4 0.5 0.00072 19.3 0.5 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAAP01003727.1_4 - 0.0041 17.0 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 AAAP01003727.1_4 - 0.0064 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 AAAP01003727.1_4 - 0.0067 15.8 0.2 0.022 14.1 0.2 1.8 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.29 AAAP01003727.1_4 - 0.0096 16.4 0.0 0.087 13.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAAP01003727.1_4 - 0.01 16.0 0.2 0.095 12.9 0.2 2.7 2 1 0 2 2 2 0 AAA domain Zot PF05707.12 AAAP01003727.1_4 - 0.027 14.1 0.1 0.067 12.8 0.1 1.6 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.27 AAAP01003727.1_4 - 0.041 14.4 0.0 0.079 13.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 AAAP01003727.1_4 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 AAAP01003727.1_4 - 0.13 11.5 0.1 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 AAAP01003727.1_4 - 0.14 11.9 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 AAAP01003727.1_4 - 0.14 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 AAAP01003727.1_4 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.9 AAAP01003727.1_4 - 0.17 11.0 0.1 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 AAAP01003727.1_4 - 0.18 11.0 0.0 0.4 9.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Roc PF08477.13 AAAP01003727.1_4 - 0.22 11.7 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 AAAP01003727.1_4 - 0.26 11.2 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DEC-1_N PF04625.13 AAAP01003727.1_4 - 0.28 10.1 7.3 0.54 9.2 7.3 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DEAD PF00270.29 AAAP01003727.1_5 - 0.02 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 AAAP01003727.1_5 - 0.2 11.4 2.0 1.1 9.0 2.0 2.1 1 1 0 1 1 1 0 AAA domain Antimicrobial13 PF08108.11 AAAP01003727.1_5 - 0.56 10.4 2.1 1.8 8.8 2.1 1.8 1 0 0 1 1 1 0 Halocidin family SpoVG PF04026.12 AAAP01003727.1_7 - 0.0004 20.5 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 SpoVG CbiA PF01656.23 AAAP01003728.1_1 - 0.0041 17.2 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAAP01003728.1_1 - 0.0055 16.2 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Pribosyltran PF00156.27 AAAP01003728.1_2 - 0.015 14.8 0.0 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosyl transferase domain PLDc_3 PF13918.6 AAAP01003728.1_3 - 0.2 11.3 0.0 0.23 11.1 0.0 1.0 1 0 0 1 1 1 0 PLD-like domain TrwC PF08751.11 AAAP01003728.1_4 - 7.6e-67 225.9 0.8 9.6e-67 225.6 0.8 1.0 1 0 0 1 1 1 1 TrwC relaxase AAA_30 PF13604.6 AAAP01003728.1_5 - 3.9e-47 160.5 8.0 9.6e-47 159.2 8.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAAP01003728.1_5 - 9.6e-14 51.9 0.1 1.1e-12 48.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 AAAP01003728.1_5 - 2e-08 34.4 0.4 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAAP01003728.1_5 - 0.0014 18.5 0.6 1.2 8.8 0.1 2.8 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 AAAP01003728.1_5 - 0.0049 16.8 0.1 0.016 15.1 0.1 1.9 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 AAAP01003728.1_5 - 0.018 14.3 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase DUF4350 PF14258.6 AAAP01003728.1_5 - 0.028 14.9 1.0 0.13 12.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) UvrD-helicase PF00580.21 AAAP01003728.1_5 - 0.06 12.9 1.1 0.12 11.9 1.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CbiA PF01656.23 AAAP01003728.1_5 - 0.12 12.4 2.1 0.36 10.9 2.1 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AAAP01003728.1_5 - 0.12 12.6 0.4 2.4 8.4 0.4 2.6 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 AAAP01003728.1_5 - 0.16 11.8 2.0 0.42 10.5 2.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 AAAP01003728.1_5 - 0.26 11.3 0.0 0.48 10.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HNH_3 PF13392.6 AAAP01003728.1_6 - 0.022 14.5 0.2 0.032 14.0 0.2 1.3 1 0 0 1 1 1 0 HNH endonuclease rve PF00665.26 AAAP01003728.1_7 - 1.3e-15 57.7 0.0 2.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 AAAP01003728.1_7 - 1.6e-06 27.7 0.2 6.9e-06 25.7 0.2 2.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 AAAP01003728.1_7 - 9.9e-05 22.2 1.7 0.00056 19.7 0.6 2.8 2 1 0 2 2 2 1 MarR family CENP-B_N PF04218.13 AAAP01003728.1_7 - 0.00044 19.8 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4_2 PF08281.12 AAAP01003728.1_7 - 0.0019 17.9 0.4 0.045 13.4 0.1 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.19 AAAP01003728.1_7 - 0.0032 17.0 0.1 0.0088 15.6 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AAAP01003728.1_7 - 0.0036 17.0 1.2 0.011 15.5 1.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01003728.1_7 - 0.023 14.7 0.2 0.023 14.7 0.2 3.2 4 0 0 4 4 3 0 Winged helix-turn helix HTH_7 PF02796.15 AAAP01003728.1_7 - 0.031 14.4 0.3 0.07 13.2 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 AAAP01003728.1_7 - 0.034 14.1 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 AAAP01003728.1_7 - 0.099 12.7 1.1 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 AAAP01003728.1_7 - 0.12 12.8 0.0 0.43 11.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01003728.1_7 - 7.8 6.7 10.3 0.51 10.5 0.1 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain IstB_IS21 PF01695.17 AAAP01003728.1_8 - 2.1e-65 219.8 0.0 2.5e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein IstB_IS21_ATP PF08483.11 AAAP01003728.1_8 - 1.8e-09 37.4 0.1 3.6e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding N-terminal AAA_22 PF13401.6 AAAP01003728.1_8 - 0.00034 20.9 0.0 0.00071 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01003728.1_8 - 0.00071 19.2 0.1 0.0018 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003728.1_8 - 0.0051 17.2 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 AAAP01003728.1_8 - 0.056 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAAP01003728.1_8 - 0.058 12.8 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 AAAP01003728.1_8 - 0.093 13.3 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 AAAP01003728.1_8 - 0.23 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein MoeA_N PF03453.17 AAAP01003728.1_9 - 0.022 14.5 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) Cytochrom_B559 PF00283.19 AAAP01003729.1_1 - 0.0066 15.9 1.5 0.014 14.9 1.5 1.5 1 0 0 1 1 1 1 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits 4HBT PF03061.22 AAAP01003729.1_2 - 1.6e-13 50.8 0.4 2.7e-13 50.1 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAAP01003729.1_2 - 0.00082 19.5 0.1 0.001 19.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Cep57_CLD_2 PF14197.6 AAAP01003729.1_2 - 0.032 14.3 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GST_C PF00043.25 AAAP01003729.1_2 - 0.083 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thiolase_N PF00108.23 AAAP01003729.1_3 - 2.2e-74 250.1 0.1 2.8e-74 249.8 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAAP01003729.1_3 - 1.8e-46 156.8 1.3 4.5e-46 155.5 1.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01003729.1_3 - 4.7e-05 23.1 0.2 4.7e-05 23.1 0.2 1.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding_C_2 PF14535.6 AAAP01003729.1_4 - 1.5e-27 95.7 0.1 4.3e-27 94.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AAAP01003729.1_4 - 2.4e-14 52.8 0.1 2.4e-14 52.8 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme LuxE PF04443.12 AAAP01003729.1_4 - 3.9e-07 29.4 0.0 0.00017 20.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-protein synthetase, LuxE Hemerythrin PF01814.23 AAAP01003729.1_5 - 1.6e-08 35.3 6.9 1.7e-08 35.1 6.9 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PHD_like PF12910.7 AAAP01003729.1_5 - 0.0034 17.4 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system OHCU_decarbox PF09349.10 AAAP01003729.1_5 - 0.067 13.7 0.1 0.076 13.5 0.1 1.2 1 0 0 1 1 1 0 OHCU decarboxylase BATS PF06968.13 AAAP01003729.1_6 - 1.4e-09 37.9 0.0 1.5e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AAAP01003729.1_7 - 4.7e-16 59.6 0.1 7.3e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily GyrI-like PF06445.15 AAAP01003729.1_8 - 1.8e-25 90.0 0.0 2e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AAAP01003729.1_8 - 5.6e-06 26.6 0.0 0.053 13.7 0.0 2.1 1 1 1 2 2 2 2 Integron-associated effector binding protein Aminotran_1_2 PF00155.21 AAAP01003729.1_9 - 6.8e-52 176.8 0.0 8.1e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01003729.1_9 - 7.2e-07 28.1 0.0 1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 AAAP01003729.1_9 - 0.014 14.0 0.0 0.021 13.4 0.0 1.3 1 1 0 1 1 1 0 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 AAAP01003729.1_9 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAAP01003729.1_9 - 0.05 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HAMP PF00672.25 AAAP01003730.1_1 - 2.8e-09 37.2 0.0 6.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 HAMP domain PAS_3 PF08447.12 AAAP01003730.1_1 - 2e-05 24.8 0.0 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold CHASE8 PF17152.4 AAAP01003730.1_1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain DUF4692 PF15763.5 AAAP01003730.1_1 - 0.035 14.6 0.1 0.059 13.8 0.1 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) sCache_3_2 PF17203.4 AAAP01003730.1_1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 Phosphonate-bd PF12974.7 AAAP01003730.1_2 - 7.3e-34 117.4 0.1 8.9e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAAP01003730.1_2 - 0.00015 21.2 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAAP01003730.1_2 - 0.013 15.4 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 NMT1/THI5 like PBP_like PF12727.7 AAAP01003730.1_2 - 0.025 13.7 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 PBP superfamily domain HTH_28 PF13518.6 AAAP01003730.1_4 - 6.5e-07 29.4 0.3 1.3e-06 28.4 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01003730.1_4 - 1.1e-05 25.3 0.1 1.1e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 AAAP01003730.1_4 - 0.00067 19.9 0.3 0.0019 18.5 0.3 1.8 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01003730.1_4 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Sigma54_activat PF00158.26 AAAP01003730.1_5 - 3.3e-71 238.4 0.3 4.7e-71 237.9 0.3 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01003730.1_5 - 2.4e-21 76.3 0.0 5.4e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01003730.1_5 - 1.6e-13 50.2 0.3 6.6e-13 48.2 0.3 2.2 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family GAF PF01590.26 AAAP01003730.1_5 - 2.9e-11 44.1 0.0 5.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain AAA_5 PF07728.14 AAAP01003730.1_5 - 7.1e-10 39.0 0.1 7e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) GAF_2 PF13185.6 AAAP01003730.1_5 - 3.2e-09 37.2 0.0 6.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain Mg_chelatase PF01078.21 AAAP01003730.1_5 - 2.1e-06 27.3 0.7 3.9e-05 23.1 0.7 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 AAAP01003730.1_5 - 2.7e-06 27.9 0.2 7e-06 26.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) GAF_3 PF13492.6 AAAP01003730.1_5 - 6.5e-06 26.5 0.2 2.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 GAF domain AAA_2 PF07724.14 AAAP01003730.1_5 - 1.5e-05 25.2 0.0 7.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Torsin PF06309.11 AAAP01003730.1_5 - 0.042 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 AAAP01003730.1_5 - 0.065 13.6 0.5 0.23 11.8 0.1 2.2 3 0 0 3 3 3 0 AAA ATPase domain HTH_28 PF13518.6 AAAP01003730.1_5 - 0.073 13.2 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_30 PF13604.6 AAAP01003730.1_5 - 0.084 12.6 0.2 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAAP01003730.1_5 - 0.14 11.9 0.2 3.2 7.5 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein DSPc PF00782.20 AAAP01003730.1_6 - 2.2e-05 24.3 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 AAAP01003730.1_6 - 0.019 14.6 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 AAAP01003730.1_6 - 0.051 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate MFS_1 PF07690.16 AAAP01003731.1_1 - 1.5e-21 76.7 46.8 2.8e-21 75.8 47.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 AAAP01003731.1_1 - 1.7e-10 40.0 33.7 2.3e-10 39.7 33.7 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 AAAP01003731.1_1 - 1.2e-06 27.7 24.8 5.6e-06 25.5 7.0 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 AAAP01003731.1_1 - 0.52 8.5 4.2 1.7 6.8 4.2 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YfhO PF09586.10 AAAP01003731.1_1 - 9.3 4.3 7.8 1.3 7.1 3.8 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF445 PF04286.12 AAAP01003731.1_2 - 6e-91 306.0 0.0 6.8e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DnaI_N PF07319.11 AAAP01003731.1_2 - 0.076 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus DDE_5 PF13546.6 AAAP01003731.1_3 - 1.9e-80 270.2 0.3 2.7e-80 269.6 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 AAAP01003731.1_3 - 1.1e-12 48.1 0.0 1.7e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 AAAP01003731.1_4 - 3.4e-24 84.9 2.0 3.4e-24 84.9 2.0 1.7 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) Ribosomal_L15e PF00827.17 AAAP01003731.1_4 - 0.084 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L15 DDE_Tnp_1_2 PF13586.6 AAAP01003731.1_5 - 1.7e-21 76.4 0.1 1.9e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01003731.1_5 - 2.6e-10 40.3 1.9 1.1e-08 35.0 1.9 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003731.1_5 - 0.0092 15.7 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AAAP01003731.1_5 - 0.027 14.5 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Hemerythrin PF01814.23 AAAP01003731.1_6 - 1.7e-08 35.2 0.2 4.1e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Transketolase_C PF02780.20 AAAP01003732.1_1 - 3.7e-41 139.9 0.4 5.8e-41 139.3 0.4 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 AAAP01003732.1_1 - 6.5e-37 126.9 0.0 1.1e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 AAAP01003732.1_1 - 0.00019 21.7 0.1 0.00033 20.9 0.1 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Alba PF01918.21 AAAP01003732.1_1 - 0.004 17.0 0.2 0.0073 16.1 0.2 1.3 1 0 0 1 1 1 1 Alba 2-oxoacid_dh PF00198.23 AAAP01003732.1_2 - 1.8e-85 286.1 0.0 2.3e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAAP01003732.1_2 - 8.8e-20 70.3 0.4 1.8e-19 69.4 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AAAP01003732.1_2 - 1.2e-15 57.5 1.2 1.2e-15 57.5 1.2 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAAP01003732.1_2 - 0.0069 16.2 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like Ribosomal_60s PF00428.19 AAAP01003732.1_2 - 0.32 11.6 28.1 0.78 10.4 9.5 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3597 PF12200.8 AAAP01003732.1_2 - 1.9 9.0 8.2 6.6 7.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DEC-1_N PF04625.13 AAAP01003732.1_2 - 1.9 7.4 18.5 0.83 8.6 3.5 2.2 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Pyr_redox_2 PF07992.14 AAAP01003732.1_5 - 9.8e-64 215.4 2.5 9.8e-64 215.4 2.5 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAAP01003732.1_5 - 7.1e-37 126.0 2.1 1.9e-36 124.7 2.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAAP01003732.1_5 - 2e-22 79.5 8.2 2.1e-20 73.0 0.4 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003732.1_5 - 2.4e-15 56.6 2.2 1.4e-14 54.1 2.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003732.1_5 - 3.4e-10 39.6 7.1 6.4e-10 38.7 3.0 2.7 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AAAP01003732.1_5 - 6.7e-09 35.6 0.3 6.7e-09 35.6 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003732.1_5 - 7e-07 28.7 0.2 7e-07 28.7 0.2 3.8 3 1 2 5 5 5 1 FAD binding domain HI0933_like PF03486.14 AAAP01003732.1_5 - 5.5e-06 25.4 11.4 0.00064 18.5 0.8 3.2 3 1 1 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 AAAP01003732.1_5 - 0.00014 21.3 7.1 0.046 13.0 0.1 3.5 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AAAP01003732.1_5 - 0.00014 22.0 5.1 0.013 15.7 0.5 3.0 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003732.1_5 - 0.00045 19.9 14.6 0.42 10.1 2.6 4.0 3 1 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 AAAP01003732.1_5 - 0.0014 18.0 2.3 0.0036 16.7 0.0 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AAAP01003732.1_5 - 0.0023 17.3 3.2 0.097 11.9 0.2 2.8 2 1 1 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 AAAP01003732.1_5 - 0.0091 15.9 0.9 0.0091 15.9 0.9 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 AAAP01003732.1_5 - 0.029 13.2 0.3 0.089 11.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Ribosomal_S9 PF00380.19 AAAP01003732.1_5 - 0.09 13.3 0.8 5.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S9/S16 NAD_binding_7 PF13241.6 AAAP01003732.1_5 - 0.6 10.6 5.1 0.55 10.7 0.1 3.0 3 1 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 AAAP01003732.1_5 - 0.69 8.9 5.1 1.2 8.1 0.8 3.0 2 2 0 2 2 2 0 Lycopene cyclase protein YajC PF02699.15 AAAP01003732.1_5 - 8.3 6.4 6.8 4.7 7.2 2.1 2.5 1 1 1 2 2 2 0 Preprotein translocase subunit Radical_SAM PF04055.21 AAAP01003732.1_6 - 9e-14 52.2 0.2 3.1e-13 50.4 0.0 1.9 2 1 1 3 3 3 1 Radical SAM superfamily LIAS_N PF16881.5 AAAP01003732.1_6 - 2.1e-07 31.3 0.2 4e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Polyketide_cyc PF03364.20 AAAP01003732.1_7 - 2.7e-32 111.7 0.1 3e-32 111.6 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAAP01003732.1_7 - 5.1e-10 39.8 0.0 6.1e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport cNMP_binding PF00027.29 AAAP01003732.1_8 - 2.4e-22 78.8 0.0 4.4e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003732.1_8 - 1e-17 63.9 0.0 2.1e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003732.1_8 - 1.4e-06 27.9 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 AAAP01003732.1_8 - 1.7e-06 27.8 0.1 3.2e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 AAAP01003732.1_8 - 3e-06 26.8 0.0 8.3e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 AAAP01003732.1_8 - 5.8e-05 22.6 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AAAP01003732.1_8 - 0.00017 21.6 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 AAAP01003732.1_8 - 0.00033 20.3 0.0 0.00078 19.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 AAAP01003732.1_8 - 0.00045 19.7 0.0 0.0014 18.1 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Rrf2 PF02082.20 AAAP01003732.1_8 - 0.00082 19.7 0.1 0.0018 18.6 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 AAAP01003732.1_8 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 AAAP01003732.1_8 - 0.004 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_CodY PF08222.11 AAAP01003732.1_8 - 0.0063 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 CodY helix-turn-helix domain HTH_11 PF08279.12 AAAP01003732.1_8 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 AAAP01003732.1_8 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix ssDNA-exonuc_C PF10141.9 AAAP01003732.1_8 - 0.013 15.1 0.0 0.49 10.0 0.0 2.1 1 1 1 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain HTH_3 PF01381.22 AAAP01003732.1_8 - 0.023 14.8 0.1 0.059 13.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_36 PF13730.6 AAAP01003732.1_8 - 0.023 14.6 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAAP01003732.1_8 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_19 PF12844.7 AAAP01003732.1_8 - 0.054 13.5 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 AAAP01003732.1_8 - 0.064 13.3 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_10 PF04967.12 AAAP01003732.1_8 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain DUF603 PF04645.12 AAAP01003732.1_8 - 0.081 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Sigma70_r3 PF04539.16 AAAP01003732.1_8 - 0.091 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_38 PF13936.6 AAAP01003732.1_8 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_rep_O PF04492.13 AAAP01003732.1_8 - 0.12 13.0 0.0 3.8 8.1 0.0 2.8 2 1 0 2 2 2 0 Bacteriophage replication protein O YdaS_antitoxin PF15943.5 AAAP01003732.1_8 - 0.13 12.2 0.0 0.44 10.5 0.0 2.0 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT FeoC PF09012.10 AAAP01003732.1_8 - 0.13 12.4 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 1 0 FeoC like transcriptional regulator Tom6 PF17112.5 AAAP01003732.1_9 - 0.067 12.7 0.5 0.067 12.7 0.5 1.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal EVI2A PF05399.11 AAAP01003732.1_9 - 0.21 11.2 0.9 0.24 11.0 0.9 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) CobW_C PF07683.14 AAAP01003733.1_1 - 3e-19 68.7 0.0 3.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.19 AAAP01003733.1_2 - 3.2e-47 160.4 0.0 3.6e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 AAAP01003733.1_2 - 0.0018 17.9 0.7 0.76 9.4 0.0 2.1 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 AAAP01003733.1_2 - 0.0079 16.1 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 AAAP01003733.1_2 - 0.0088 15.6 0.2 3.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 AAAP01003733.1_2 - 0.011 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003733.1_2 - 0.012 15.8 0.3 0.023 14.8 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAAP01003733.1_2 - 0.031 14.5 0.1 0.082 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AAAP01003733.1_2 - 0.043 13.8 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AAAP01003733.1_2 - 0.068 13.6 0.3 0.089 13.2 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 AAAP01003733.1_2 - 0.08 12.4 1.3 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 AAAP01003733.1_2 - 0.12 12.1 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AAAP01003733.1_2 - 0.12 12.2 0.1 0.52 10.2 0.1 1.9 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 AAAP01003733.1_2 - 0.15 12.1 0.1 1.7 8.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRA-CH PF01502.18 AAAP01003733.1_3 - 1.2e-33 114.8 0.3 1.6e-33 114.3 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase ZnuA PF01297.17 AAAP01003733.1_4 - 8.4e-61 205.6 0.0 9.5e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic FUR PF01475.19 AAAP01003733.1_5 - 1.1e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ferric uptake regulator family PadR PF03551.14 AAAP01003733.1_5 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_IclR PF09339.10 AAAP01003733.1_5 - 0.12 12.2 0.5 0.55 10.1 0.1 2.4 2 1 1 3 3 3 0 IclR helix-turn-helix domain ABC_tran PF00005.27 AAAP01003733.1_6 - 2e-26 93.1 0.0 2.9e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003733.1_6 - 1e-09 38.6 0.1 0.00077 19.4 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003733.1_6 - 0.00055 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AAAP01003733.1_6 - 0.0014 18.1 0.0 0.0099 15.3 0.0 1.9 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAAP01003733.1_6 - 0.0024 18.1 0.0 0.0054 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003733.1_6 - 0.0041 17.5 0.3 0.0066 16.8 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003733.1_6 - 0.0098 15.6 0.6 0.022 14.5 0.6 1.6 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAAP01003733.1_6 - 0.017 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01003733.1_6 - 0.034 14.7 0.0 0.045 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003733.1_6 - 0.045 13.7 0.0 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 AAAP01003733.1_6 - 0.054 13.7 0.0 1.2 9.4 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 AAAP01003733.1_6 - 0.069 12.9 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC-3 PF00950.17 AAAP01003733.1_7 - 4.6e-70 236.1 25.1 5.2e-70 235.9 25.1 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AAAP01003733.1_7 - 8.8e-07 28.2 30.5 1.8e-06 27.2 30.5 1.6 1 1 0 1 1 1 1 FecCD transport family HATPase_c PF02518.26 AAAP01003733.1_9 - 4.3e-24 85.2 0.0 1.1e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE PF03924.13 AAAP01003733.1_9 - 5.5e-17 62.3 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 CHASE domain HisKA PF00512.25 AAAP01003733.1_9 - 4.5e-11 42.6 0.1 2.2e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003733.1_9 - 2.4e-09 37.2 0.0 5.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AAAP01003733.1_9 - 4.9e-05 23.2 0.0 9.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_9 PF13426.7 AAAP01003733.1_9 - 5.3e-05 23.4 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003733.1_9 - 0.00012 22.0 0.0 0.00044 20.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003733.1_9 - 0.00013 22.2 0.1 0.00035 20.8 0.1 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AAAP01003733.1_9 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AAAP01003733.1_9 - 0.0072 16.6 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAAP01003733.1_9 - 0.11 12.5 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain MgtC PF02308.16 AAAP01003733.1_10 - 1.8e-33 115.4 13.5 2.4e-33 115.0 13.5 1.2 1 0 0 1 1 1 1 MgtC family YukD PF08817.10 AAAP01003733.1_10 - 0.13 13.0 0.1 0.36 11.5 0.1 1.8 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD TraL PF07178.11 AAAP01003733.1_10 - 1.1 9.7 3.6 2.3 8.7 0.4 2.5 2 1 0 2 2 2 0 TraL protein OEP PF02321.18 AAAP01003733.1_11 - 1.6e-19 70.5 6.6 2e-19 70.2 6.6 1.0 1 0 0 1 1 1 1 Outer membrane efflux protein AAA_PrkA PF08298.11 AAAP01003734.1_1 - 3.3e-151 503.2 0.0 4.5e-151 502.8 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain PrkA PF06798.12 AAAP01003734.1_1 - 1.3e-76 257.6 2.3 1.8e-76 257.2 2.3 1.2 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_16 PF13191.6 AAAP01003734.1_1 - 0.0012 19.3 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003734.1_1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01003734.1_1 - 0.096 12.7 1.9 0.25 11.3 0.1 2.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) DUF444 PF04285.12 AAAP01003734.1_2 - 4.8e-176 585.9 0.0 5.5e-176 585.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) VWA_CoxE PF05762.14 AAAP01003734.1_2 - 0.024 14.0 3.3 0.22 10.9 3.3 2.6 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Dyp_perox PF04261.12 AAAP01003734.1_2 - 0.091 11.7 0.0 0.77 8.7 0.0 2.0 2 0 0 2 2 2 0 Dyp-type peroxidase family SpoVR PF04293.13 AAAP01003734.1_3 - 2.2e-58 197.9 1.1 2.6e-58 197.7 1.1 1.0 1 0 0 1 1 1 1 SpoVR like protein SpoVR PF04293.13 AAAP01003734.1_4 - 1.1e-86 291.2 0.2 1.2e-86 291.0 0.2 1.0 1 0 0 1 1 1 1 SpoVR like protein DUF3016 PF11454.8 AAAP01003734.1_4 - 0.051 13.3 1.3 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) TPR_16 PF13432.6 AAAP01003734.1_5 - 1.1e-23 83.6 34.7 1.9e-05 25.2 0.1 7.6 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003734.1_5 - 1.1e-23 83.4 28.8 0.00017 22.1 4.8 7.5 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003734.1_5 - 8.2e-23 78.6 12.4 0.014 15.4 0.3 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003734.1_5 - 9.4e-19 66.4 1.4 0.037 13.8 0.0 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003734.1_5 - 2.6e-16 58.9 40.4 0.0011 19.6 0.1 10.0 3 2 6 9 9 9 6 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 AAAP01003734.1_5 - 1.4e-13 50.8 0.0 1.6e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 9 (heptosyltransferase) TPR_17 PF13431.6 AAAP01003734.1_5 - 3.4e-13 49.0 2.1 1.2 9.7 0.0 8.6 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003734.1_5 - 3.7e-12 45.4 0.2 2.3 8.7 0.1 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003734.1_5 - 7.1e-12 45.5 34.6 0.00077 19.7 1.5 9.5 5 3 5 10 10 10 6 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003734.1_5 - 3.8e-08 32.9 33.0 0.036 13.9 0.7 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003734.1_5 - 2.6e-07 30.2 2.8 0.028 14.1 0.1 5.5 4 1 2 6 6 5 1 TPR repeat ANAPC3 PF12895.7 AAAP01003734.1_5 - 1e-06 28.9 0.0 0.088 13.0 0.0 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AAAP01003734.1_5 - 1.3e-05 24.9 15.8 0.58 10.3 0.1 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat Coatomer_E PF04733.14 AAAP01003734.1_5 - 0.00029 20.3 1.8 0.25 10.7 0.1 2.7 2 1 1 3 3 3 2 Coatomer epsilon subunit TPR_15 PF13429.6 AAAP01003734.1_5 - 0.0006 19.1 13.9 2.2 7.4 0.0 4.9 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 AAAP01003734.1_5 - 0.0052 17.0 15.6 0.11 12.7 1.7 4.5 4 1 1 5 5 5 2 Tetratrico peptide repeat TPR_9 PF13371.6 AAAP01003734.1_5 - 0.073 13.2 34.2 0.023 14.8 6.8 6.2 4 1 3 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003734.1_5 - 0.2 12.0 12.2 16 5.9 2.8 5.1 3 3 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003734.1_5 - 0.25 12.1 11.1 3.5 8.4 0.1 6.4 8 0 0 8 8 5 0 Tetratricopeptide repeat CMAS PF02353.20 AAAP01003734.1_5 - 0.25 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HrpB1_HrpK PF09613.10 AAAP01003734.1_5 - 0.66 9.6 11.5 2.3 7.9 0.5 3.7 3 1 1 4 4 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 AAAP01003734.1_5 - 0.9 9.2 10.3 2.8 7.6 1.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 AAAP01003734.1_5 - 2.4 9.1 64.9 0.44 11.3 0.3 13.2 12 1 1 13 13 12 0 Tetratricopeptide repeat POR PF01558.18 AAAP01003734.1_6 - 1.7e-08 34.8 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase ECH_1 PF00378.20 AAAP01003735.1_1 - 1.4e-33 116.2 0.0 1.8e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003735.1_1 - 6.3e-24 85.1 0.2 7.5e-24 84.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short_C2 PF13561.6 AAAP01003735.1_2 - 3.7e-63 213.2 0.1 4.4e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003735.1_2 - 3e-58 196.5 0.0 4e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003735.1_2 - 2.4e-14 53.6 0.1 3.4e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003735.1_2 - 2.2e-05 24.1 0.0 5.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003735.1_2 - 0.005 16.3 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_25 PF13649.6 AAAP01003735.1_2 - 0.034 14.8 0.0 0.067 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ECH_1 PF00378.20 AAAP01003735.1_3 - 1.7e-48 165.1 0.1 2.1e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003735.1_3 - 2.2e-31 109.6 0.0 2.5e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_79n PF03662.14 AAAP01003735.1_3 - 0.021 13.8 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Abhydrolase_3 PF07859.13 AAAP01003735.1_4 - 3.8e-61 206.6 0.5 4.6e-61 206.3 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 AAAP01003735.1_4 - 3.1e-06 26.3 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 AAAP01003735.1_4 - 0.012 14.4 0.0 0.055 12.3 0.0 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 AAAP01003735.1_4 - 0.045 13.2 0.6 0.47 9.9 1.2 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Thiolase_N PF00108.23 AAAP01003735.1_5 - 1.1e-66 224.9 0.0 1.6e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAAP01003735.1_5 - 3.3e-43 146.3 1.7 6.3e-43 145.3 1.7 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01003735.1_5 - 0.00013 21.7 0.2 0.00013 21.7 0.2 2.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain 3HCDH_N PF02737.18 AAAP01003735.1_6 - 1.8e-56 190.8 1.6 2.6e-56 190.4 1.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAAP01003735.1_6 - 7.9e-42 141.8 0.1 1.4e-23 83.3 0.0 2.7 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AAAP01003735.1_6 - 0.0027 17.9 3.5 0.0065 16.7 3.5 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01003735.1_6 - 0.0046 16.4 0.2 0.0083 15.5 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 AAAP01003735.1_6 - 0.074 13.6 0.2 0.17 12.4 0.2 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ECH_1 PF00378.20 AAAP01003735.1_7 - 9.2e-77 257.7 1.4 1.1e-76 257.4 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003735.1_7 - 5.3e-40 137.9 3.6 4.2e-36 125.1 1.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HTH_IclR PF09339.10 AAAP01003735.1_8 - 9.7e-18 63.7 0.0 2.5e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 AAAP01003735.1_8 - 4.2e-13 49.3 0.0 6.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator MarR_2 PF12802.7 AAAP01003735.1_8 - 0.0013 18.5 0.1 0.008 16.1 0.0 2.3 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 AAAP01003735.1_8 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AAAP01003735.1_8 - 0.036 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 AAAP01003735.1_8 - 0.037 14.4 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HTH_Crp_2 PF13545.6 AAAP01003735.1_8 - 0.056 13.4 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR PF01047.22 AAAP01003735.1_8 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family Acyl-CoA_dh_1 PF00441.24 AAAP01003735.1_9 - 1.4e-48 164.9 2.6 2.3e-48 164.2 2.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003735.1_9 - 4.1e-31 107.1 0.0 8.7e-31 106.0 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAAP01003735.1_9 - 9.3e-30 103.6 0.0 2.3e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01003735.1_9 - 8.8e-21 74.6 1.3 1.6e-20 73.7 1.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 AAAP01003735.1_9 - 0.0057 16.4 0.0 0.028 14.1 0.0 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AMP-binding PF00501.28 AAAP01003735.1_10 - 5.5e-49 166.9 0.0 6.5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PAS_8 PF13188.7 AAAP01003736.1_1 - 0.00031 20.7 0.0 0.00075 19.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003736.1_1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold Potyvirid-P3 PF13608.6 AAAP01003736.1_1 - 0.016 14.2 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein HAMP PF00672.25 AAAP01003736.1_1 - 0.039 14.3 1.5 6.2 7.3 0.5 3.7 2 2 0 2 2 2 0 HAMP domain OTCace_N PF02729.21 AAAP01003736.1_1 - 0.16 12.0 1.0 0.45 10.5 0.1 2.0 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain His_Phos_1 PF00300.22 AAAP01003736.1_2 - 4.9e-06 26.4 0.0 7.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Response_reg PF00072.24 AAAP01003736.1_3 - 1.2e-25 89.8 0.4 3.2e-25 88.5 0.0 1.9 3 0 0 3 3 3 1 Response regulator receiver domain HD_5 PF13487.6 AAAP01003736.1_3 - 2.3e-17 63.0 0.0 1e-16 60.9 0.0 2.0 1 1 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003736.1_3 - 4.3e-13 49.5 0.0 3.8e-12 46.5 0.0 2.5 2 1 0 2 2 2 1 HD domain Response_reg PF00072.24 AAAP01003736.1_4 - 8.3e-26 90.4 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003736.1_4 - 0.084 12.9 1.0 0.2 11.7 0.4 1.9 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain MCPsignal PF00015.21 AAAP01003736.1_5 - 1.1e-32 113.2 48.2 4.5e-32 111.2 25.4 3.6 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAAP01003736.1_5 - 1.1e-19 70.7 0.0 1.1e-19 70.7 0.0 3.9 3 2 2 5 5 5 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 AAAP01003736.1_5 - 1.7e-15 57.4 0.9 1.7e-15 57.4 0.9 3.5 3 2 1 4 4 3 1 Tar ligand binding domain homologue HAMP PF00672.25 AAAP01003736.1_5 - 1.9e-08 34.5 0.0 1.9e-08 34.5 0.0 5.3 7 1 1 8 8 4 1 HAMP domain DUF1664 PF07889.12 AAAP01003736.1_5 - 0.0002 21.4 15.9 0.12 12.4 0.7 4.8 3 2 1 4 4 4 2 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 AAAP01003736.1_5 - 0.00037 20.8 7.5 0.7 10.3 0.1 5.1 3 2 1 5 5 5 1 Syntaxin-like protein DUF948 PF06103.11 AAAP01003736.1_5 - 0.00063 20.0 25.6 0.11 12.7 2.1 5.8 3 1 2 6 6 6 3 Bacterial protein of unknown function (DUF948) PIN_8 PF18476.1 AAAP01003736.1_5 - 0.039 13.8 12.3 1.2 8.9 0.2 3.5 2 1 2 4 4 4 0 PIN like domain BAR_3 PF16746.5 AAAP01003736.1_5 - 0.1 12.3 0.6 0.77 9.4 0.0 2.5 3 0 0 3 3 3 0 BAR domain of APPL family DUF3450 PF11932.8 AAAP01003736.1_5 - 0.17 11.2 17.9 0.017 14.4 4.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 AAAP01003736.1_5 - 0.18 11.5 19.3 0.089 12.5 3.4 2.9 1 1 0 2 2 2 0 Laminin Domain I Golgin_A5 PF09787.9 AAAP01003736.1_5 - 0.32 10.4 10.8 1.4 8.3 2.1 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF16 PF01519.16 AAAP01003736.1_5 - 0.38 11.3 8.6 2.2 8.8 0.0 4.1 2 1 1 4 4 4 0 Protein of unknown function DUF16 Prominin PF05478.11 AAAP01003736.1_5 - 0.4 8.6 8.9 0.37 8.7 1.1 2.8 2 1 0 3 3 3 0 Prominin Dynactin_p22 PF07426.11 AAAP01003736.1_5 - 0.48 10.3 2.7 0.79 9.6 0.2 2.5 3 0 0 3 3 3 0 Dynactin subunit p22 COG6 PF06419.11 AAAP01003736.1_5 - 1.2 7.2 6.6 0.96 7.6 1.3 2.3 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 IFT57 PF10498.9 AAAP01003736.1_5 - 1.4 7.8 6.7 3 6.7 0.4 2.6 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 AAAP01003736.1_5 - 1.5 7.6 14.6 3.9 6.3 0.8 3.5 3 1 1 4 4 4 0 Spc7 kinetochore protein PhaP_Bmeg PF09602.10 AAAP01003736.1_5 - 1.6 8.6 5.5 11 5.9 0.2 3.7 3 2 1 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) COG2 PF06148.11 AAAP01003736.1_5 - 1.7 8.7 13.2 37 4.4 1.2 4.8 2 1 4 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 AAAP01003736.1_5 - 1.8 7.4 8.2 0.56 9.1 1.5 2.8 2 0 0 2 2 2 0 Vps53-like, N-terminal YscO-like PF16789.5 AAAP01003736.1_5 - 1.9 8.5 10.6 0.17 11.9 0.4 3.0 3 0 0 3 3 3 0 YscO-like protein IFT20 PF14931.6 AAAP01003736.1_5 - 2.2 8.5 11.9 7.6 6.7 0.4 4.7 2 1 3 5 5 5 0 Intraflagellar transport complex B, subunit 20 FlaC_arch PF05377.11 AAAP01003736.1_5 - 2.8 8.4 6.6 18 5.8 0.0 4.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 AAAP01003736.1_5 - 3.6 6.7 6.0 3.3 6.9 0.3 2.7 3 0 0 3 3 3 0 TMPIT-like protein Sec34 PF04136.15 AAAP01003736.1_5 - 5.6 6.8 6.5 38 4.1 0.5 3.9 4 2 0 4 4 4 0 Sec34-like family HIP1_clath_bdg PF16515.5 AAAP01003736.1_5 - 9.5 6.9 14.9 7.8 7.2 0.7 4.4 3 2 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cytochrom_B562 PF07361.11 AAAP01003736.1_5 - 9.6 6.9 15.8 28 5.4 3.8 4.6 2 1 3 5 5 5 0 Cytochrome b562 DUF1465 PF07323.12 AAAP01003736.1_6 - 1.4e-30 106.1 2.5 1.5e-30 106.1 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) DUF4044 PF13253.6 AAAP01003736.1_6 - 0.053 13.1 0.2 0.082 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) DUF2680 PF10925.8 AAAP01003736.1_6 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Helo_like_N PF17111.5 AAAP01003736.1_7 - 0.085 12.2 0.1 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Resolvase PF00239.21 AAAP01003736.1_8 - 5.5e-18 65.5 0.9 5.5e-18 65.5 0.9 1.6 2 0 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 AAAP01003736.1_8 - 0.0031 17.9 0.0 0.0057 17.0 0.0 1.4 1 0 0 1 1 1 1 Recombinase AP_endonuc_2 PF01261.24 AAAP01003736.1_8 - 0.04 13.3 0.2 0.34 10.3 0.2 2.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel GDP_Man_Dehyd PF16363.5 AAAP01003737.1_1 - 1.5e-88 297.4 0.0 1.8e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003737.1_1 - 1.3e-66 224.5 0.0 1.6e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003737.1_1 - 2.2e-15 56.5 0.0 2.9e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003737.1_1 - 2.1e-12 46.8 0.0 3.9e-12 45.9 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003737.1_1 - 2.8e-11 43.1 0.0 2.3e-08 33.5 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 AAAP01003737.1_1 - 3e-09 36.3 0.0 4.4e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AAAP01003737.1_1 - 0.001 18.6 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 AAAP01003737.1_1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.6 AAAP01003737.1_1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAAP01003737.1_2 - 6.6e-103 343.7 0.1 8e-103 343.5 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAAP01003737.1_2 - 3.9e-20 72.4 0.1 5.1e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003737.1_2 - 4.8e-12 45.9 0.2 3.1e-10 40.0 0.1 2.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAAP01003737.1_2 - 5e-07 29.1 5.4 6.8e-07 28.7 1.5 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003737.1_2 - 1.9e-05 24.0 0.1 4e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Male sterility protein NTP_transferase PF00483.23 AAAP01003737.1_3 - 1.9e-64 217.6 0.0 2.3e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003737.1_3 - 3e-12 47.2 0.0 3.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain AAA_lid_2 PF17863.1 AAAP01003737.1_3 - 0.14 12.0 0.0 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA lid domain CTP_transf_3 PF02348.19 AAAP01003737.1_3 - 0.23 11.3 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4096 PF13340.6 AAAP01003737.1_4 - 1.5e-22 79.6 0.2 3.2e-22 78.5 0.2 1.6 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Transposase_20 PF02371.16 AAAP01003737.1_5 - 5.5e-23 81.1 0.6 1.4e-22 79.8 0.6 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AAAP01003737.1_5 - 2.8e-17 63.0 0.0 9.7e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Transposase Glyco_transf_5 PF08323.11 AAAP01003737.1_5 - 0.094 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain DDE_Tnp_1_2 PF13586.6 AAAP01003737.1_6 - 4.5e-15 55.8 4.3 8.6e-15 54.9 4.3 1.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AAAP01003737.1_6 - 7.2e-07 29.1 6.3 2.9e-05 23.8 6.3 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AAAP01003737.1_6 - 0.09 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease TetR_N PF00440.23 AAAP01003737.1_7 - 3.5e-06 26.7 0.1 4.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 AAAP01003737.1_7 - 1.2e-05 25.2 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 AAAP01003737.1_7 - 0.0005 19.8 0.0 0.0005 19.8 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003737.1_7 - 0.00051 20.0 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003737.1_7 - 0.0014 18.7 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01003737.1_7 - 0.0066 16.2 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAAP01003737.1_7 - 0.01 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 AAAP01003737.1_7 - 0.016 15.0 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 HTH DNA binding domain Terminase_5 PF06056.12 AAAP01003737.1_7 - 0.02 14.8 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_22 PF13309.6 AAAP01003737.1_7 - 0.02 14.9 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 HTH domain HTH_AsnC-type PF13404.6 AAAP01003737.1_7 - 0.021 14.7 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Tnp_1 PF01527.20 AAAP01003737.1_7 - 0.021 15.2 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_11 PF08279.12 AAAP01003737.1_7 - 0.022 14.7 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 AAAP01003737.1_7 - 0.025 14.5 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003737.1_7 - 0.033 14.3 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family CENP-B_N PF04218.13 AAAP01003737.1_7 - 0.061 13.0 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1_2 PF13022.6 AAAP01003737.1_7 - 0.062 13.5 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_24 PF13412.6 AAAP01003737.1_7 - 0.064 12.8 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 AAAP01003737.1_7 - 0.097 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_22 PF13401.6 AAAP01003737.1_8 - 4.9e-21 75.4 0.0 1.3e-20 74.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAAP01003737.1_8 - 7.3e-06 25.8 0.0 3.5e-05 23.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain YtkA PF13115.6 AAAP01003737.1_10 - 1.8e-17 63.7 0.0 2.1e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 YtkA-like YtkA PF13115.6 AAAP01003737.1_11 - 3.9e-21 75.5 0.0 5.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 YtkA-like Cupredoxin_1 PF13473.6 AAAP01003737.1_11 - 0.056 13.6 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain FixH PF05751.11 AAAP01003737.1_11 - 0.081 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 FixH HlyD_D23 PF16576.5 AAAP01003737.1_12 - 2.9e-66 222.7 0.4 5.4e-66 221.9 0.4 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003737.1_12 - 2.8e-17 63.3 0.3 7.4e-16 58.8 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.20 AAAP01003737.1_12 - 1.2e-11 44.4 0.3 1e-10 41.3 0.3 2.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003737.1_12 - 0.00083 19.1 0.1 0.016 15.0 0.1 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003737.1_12 - 0.016 15.0 0.5 7.3 6.5 0.1 2.8 3 0 0 3 3 3 0 Biotin-requiring enzyme HlyD_2 PF12700.7 AAAP01003737.1_12 - 0.04 12.7 0.0 0.21 10.3 0.0 1.8 2 0 0 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.13 AAAP01003737.1_12 - 0.047 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Molybdopterin PF00384.22 AAAP01003738.1_1 - 1.1e-71 242.1 0.0 7.1e-71 239.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 AAAP01003738.1_1 - 1.1e-20 73.4 0.2 2.3e-20 72.4 0.2 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 AAAP01003738.1_1 - 3e-17 61.9 0.3 3e-17 61.9 0.3 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 AAAP01003738.1_1 - 6.2e-11 42.1 0.2 6.2e-11 42.1 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 AAAP01003738.1_1 - 0.022 14.5 0.5 0.36 10.6 0.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Complex1_51K PF01512.17 AAAP01003738.1_2 - 1.3e-50 171.2 0.0 1.9e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AAAP01003738.1_2 - 4e-29 100.5 0.1 7.7e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AAAP01003738.1_2 - 6.8e-10 38.7 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 SLBB domain 2Fe-2S_thioredx PF01257.19 AAAP01003738.1_3 - 8.3e-63 210.6 0.1 9.8e-63 210.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_49kDa PF00346.19 AAAP01003738.1_4 - 2.7e-126 420.2 0.0 4.1e-126 419.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 AAAP01003738.1_4 - 0.0035 16.3 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Complex1_30kDa PF00329.19 AAAP01003738.1_5 - 2.6e-47 160.4 0.0 3.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q6 PF01058.22 AAAP01003738.1_6 - 3.1e-22 78.8 0.1 4e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PPARgamma_N PF12577.8 AAAP01003738.1_6 - 0.22 12.2 0.0 0.39 11.4 0.0 1.3 1 0 0 1 1 1 0 PPAR gamma N-terminal region Oxidored_q4 PF00507.19 AAAP01003738.1_7 - 1.6e-39 134.0 2.1 1.6e-39 134.0 2.1 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Bac_DNA_binding PF00216.21 AAAP01003738.1_8 - 6.6e-33 112.8 0.0 7.2e-33 112.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003738.1_8 - 3e-05 24.1 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 AAAP01003738.1_8 - 0.0029 17.7 0.0 0.004 17.3 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 AAAP01003738.1_8 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 2C_adapt PF08793.10 AAAP01003738.1_8 - 0.053 13.7 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 2-cysteine adaptor domain DUF2267 PF10025.9 AAAP01003738.1_8 - 0.073 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Lon_C PF05362.13 AAAP01003738.1_9 - 7e-98 326.2 1.3 1e-97 325.6 1.3 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 AAAP01003738.1_9 - 5.6e-21 75.3 0.0 1.4e-20 74.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003738.1_9 - 3.6e-09 36.7 0.0 6.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 AAAP01003738.1_9 - 3.1e-08 33.5 0.0 6.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 AAAP01003738.1_9 - 8.4e-06 24.9 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 AAAP01003738.1_9 - 0.00027 21.4 0.1 0.00089 19.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 AAAP01003738.1_9 - 0.00072 19.3 0.0 0.0023 17.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AAAP01003738.1_9 - 0.0032 18.0 0.1 0.0067 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003738.1_9 - 0.0035 17.6 0.1 0.06 13.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AAAP01003738.1_9 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAAP01003738.1_9 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 AAAP01003738.1_9 - 0.025 14.5 0.1 0.82 9.6 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 AAAP01003738.1_9 - 0.03 14.5 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AAAP01003738.1_9 - 0.03 14.2 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AAAP01003738.1_9 - 0.057 13.7 0.4 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 AAAP01003738.1_9 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 AAAP01003738.1_9 - 0.062 12.5 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain TsaE PF02367.17 AAAP01003738.1_9 - 0.072 13.1 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 AAAP01003738.1_9 - 0.078 12.9 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase NTPase_1 PF03266.15 AAAP01003738.1_9 - 0.11 12.4 1.0 2.5 8.0 0.2 2.7 2 1 1 3 3 3 0 NTPase NB-ARC PF00931.22 AAAP01003738.1_9 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.23 AAAP01003738.1_9 - 0.11 11.5 0.1 0.53 9.3 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain RNA_helicase PF00910.22 AAAP01003738.1_9 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 AAAP01003738.1_9 - 0.15 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.6 AAAP01003738.1_9 - 0.17 12.1 0.4 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain HD_5 PF13487.6 AAAP01003739.1_1 - 7.9e-14 51.7 0.1 3.2e-13 49.7 0.1 1.9 1 1 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003739.1_1 - 3.3e-13 49.9 0.2 4.7e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 HD domain Peptidase_M74 PF03411.13 AAAP01003739.1_2 - 6.1e-93 310.8 0.0 7.1e-93 310.6 0.0 1.0 1 0 0 1 1 1 1 Penicillin-insensitive murein endopeptidase EspF PF04806.12 AAAP01003739.1_2 - 0.35 11.3 7.1 0.12 12.8 3.4 2.1 2 0 0 2 2 2 0 EspF protein repeat Ribosomal_S2 PF00318.20 AAAP01003739.1_3 - 1.3e-94 315.4 0.0 1.5e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 DUF454 PF04304.13 AAAP01003739.1_3 - 0.14 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF454) EF_TS PF00889.19 AAAP01003739.1_4 - 4.8e-67 225.6 0.3 6.2e-67 225.2 0.3 1.1 1 0 0 1 1 1 1 Elongation factor TS HOIP-UBA PF16678.5 AAAP01003739.1_4 - 0.018 15.0 0.1 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair UBA PF00627.31 AAAP01003739.1_4 - 0.032 14.1 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain AA_kinase PF00696.28 AAAP01003739.1_5 - 3.1e-29 102.3 1.0 3.7e-29 102.0 1.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family Frankia_peptide PF14407.6 AAAP01003739.1_5 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RRF PF01765.19 AAAP01003739.1_6 - 1.8e-62 210.1 0.7 2.1e-62 209.8 0.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor 14-3-3 PF00244.20 AAAP01003739.1_6 - 0.0085 15.6 1.1 0.014 14.9 1.1 1.3 1 0 0 1 1 1 1 14-3-3 protein DUF883 PF05957.13 AAAP01003739.1_6 - 0.07 13.7 2.5 0.22 12.2 1.7 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HTH_26 PF13443.6 AAAP01003739.1_6 - 0.1 13.1 0.0 0.25 11.8 0.0 1.7 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Prenyltransf PF01255.19 AAAP01003739.1_7 - 1.7e-78 263.2 0.0 1.9e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CTP_transf_1 PF01148.20 AAAP01003739.1_8 - 2.4e-54 184.9 12.4 4.1e-54 184.1 12.4 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 AAAP01003739.1_8 - 0.0012 18.9 1.1 0.003 17.6 1.1 1.8 1 1 0 1 1 1 1 CDP-archaeol synthase GT87 PF09594.10 AAAP01003739.1_8 - 6.4 6.4 34.2 3.1 7.5 21.7 2.7 2 1 1 3 3 3 0 Glycosyltransferase family 87 DXPR_C PF13288.6 AAAP01003739.1_9 - 1.4e-41 141.4 0.0 2.3e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AAAP01003739.1_9 - 5.9e-40 135.3 0.0 1.5e-39 134.1 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 AAAP01003739.1_9 - 1.5e-39 135.7 2.9 2.9e-39 134.7 2.9 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Peptidase_M50 PF02163.22 AAAP01003739.1_10 - 6.8e-77 258.1 1.2 8e-77 257.9 1.2 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AAAP01003739.1_10 - 1e-12 47.7 0.1 2.2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AAAP01003739.1_10 - 4e-08 33.5 0.0 7.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AAAP01003739.1_10 - 5.8e-08 33.0 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 AAAP01003739.1_10 - 0.0025 17.8 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_M50B PF13398.6 AAAP01003739.1_10 - 0.017 14.8 0.8 0.017 14.8 0.8 2.4 3 1 0 3 3 3 0 Peptidase M50B-like POTRA PF07244.15 AAAP01003739.1_11 - 1.5e-56 188.9 13.5 2.2e-16 60.2 0.3 5.1 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_1 PF08478.10 AAAP01003739.1_11 - 3e-05 24.2 0.5 12 6.3 0.0 4.4 4 0 0 4 4 4 3 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AAAP01003739.1_11 - 0.13 12.1 0.4 19 5.1 0.1 3.5 4 0 0 4 4 4 0 POTRA domain, ShlB-type PLDc_2 PF13091.6 AAAP01003740.1_1 - 0.052 13.4 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 PLD-like domain DUF697 PF05128.12 AAAP01003740.1_2 - 2.6e-05 24.0 0.2 3.1e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF697) NMT1_3 PF16868.5 AAAP01003740.1_2 - 0.12 11.8 0.1 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 NMT1-like family Tautomerase PF01361.21 AAAP01003740.1_2 - 0.18 11.8 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 Tautomerase enzyme CSD PF00313.22 AAAP01003740.1_3 - 1.8e-22 79.0 0.1 2e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01003740.1_3 - 0.00086 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain Bac_DNA_binding PF00216.21 AAAP01003740.1_4 - 2.9e-27 94.7 0.0 3.3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003740.1_4 - 5.6e-08 32.9 0.0 6.1e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 AAAP01003740.1_4 - 0.0042 17.2 0.0 0.0044 17.1 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Methyltransf_5 PF01795.19 AAAP01003740.1_4 - 0.03 13.8 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family ROS_MUCR PF05443.11 AAAP01003740.1_5 - 6.8e-36 123.1 0.0 9.3e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein zf-LYAR PF08790.11 AAAP01003740.1_5 - 0.081 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger PIN PF01850.21 AAAP01003740.1_6 - 1e-12 48.6 0.1 1.2e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 PIN domain GATase_6 PF13522.6 AAAP01003740.1_6 - 0.017 15.3 1.2 2.1 8.5 0.2 2.1 1 1 1 2 2 2 0 Glutamine amidotransferase domain PhdYeFM_antitox PF02604.19 AAAP01003740.1_7 - 6.4e-10 38.7 0.1 7.2e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system TyeA PF09059.10 AAAP01003740.1_7 - 0.098 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 TyeA Sel1 PF08238.12 AAAP01003740.1_8 - 1.1e-58 194.4 45.6 4.5e-08 33.5 0.0 10.8 11 0 0 11 11 11 10 Sel1 repeat DUF1566 PF07603.11 AAAP01003740.1_9 - 0.005 17.2 0.0 0.0056 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) ClpS PF02617.17 AAAP01003740.1_11 - 2.2e-19 69.0 0.1 3.1e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS AAA PF00004.29 AAAP01003740.1_12 - 2e-36 125.3 0.0 1.8e-25 89.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AAAP01003740.1_12 - 7.6e-09 36.2 0.0 0.0015 19.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AAAP01003740.1_12 - 2.7e-08 33.9 0.1 0.00095 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003740.1_12 - 5.3e-08 33.4 0.8 0.0032 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 AAAP01003740.1_12 - 1.6e-07 31.3 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 AAAP01003740.1_12 - 1.8e-07 31.5 2.6 0.16 12.2 0.0 4.4 3 2 1 4 4 4 2 AAA domain RNA_helicase PF00910.22 AAAP01003740.1_12 - 3.1e-07 30.8 0.0 0.02 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 AAAP01003740.1_12 - 1.2e-06 28.4 0.3 0.024 14.4 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 AAAP01003740.1_12 - 7.7e-06 26.2 0.1 0.026 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 AAAP01003740.1_12 - 7.9e-06 26.3 0.8 0.26 11.7 0.4 2.9 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 AAAP01003740.1_12 - 8.3e-06 25.6 0.0 0.0088 15.8 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 AAAP01003740.1_12 - 9.5e-06 24.8 0.1 0.056 12.4 0.1 2.2 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 AAAP01003740.1_12 - 1.5e-05 25.2 0.1 0.14 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AAAP01003740.1_12 - 1.6e-05 24.5 0.4 0.022 14.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 AAAP01003740.1_12 - 2e-05 24.6 0.1 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 AAAP01003740.1_12 - 0.00026 20.4 0.1 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AAAP01003740.1_12 - 0.00069 19.6 0.3 0.12 12.3 0.0 2.9 3 1 0 3 3 2 1 NACHT domain Cytidylate_kin PF02224.18 AAAP01003740.1_12 - 0.0012 18.7 0.1 1.3 8.7 0.0 2.7 2 1 0 2 2 2 2 Cytidylate kinase AAA_11 PF13086.6 AAAP01003740.1_12 - 0.0021 17.9 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AAAP01003740.1_12 - 0.0026 17.3 0.3 1.5 8.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 AAAP01003740.1_12 - 0.0063 15.8 0.1 0.23 10.6 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain PPV_E1_C PF00519.17 AAAP01003740.1_12 - 0.0091 14.9 0.1 1 8.1 0.0 2.2 2 0 0 2 2 2 1 Papillomavirus helicase ATPase PF06745.13 AAAP01003740.1_12 - 0.011 15.1 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 AAAP01003740.1_12 - 0.015 15.0 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01003740.1_12 - 0.022 14.9 0.1 2 8.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MethyTransf_Reg PF10119.9 AAAP01003740.1_12 - 0.024 15.3 0.0 0.088 13.5 0.0 1.9 2 0 0 2 2 1 0 Predicted methyltransferase regulatory domain AAA_19 PF13245.6 AAAP01003740.1_12 - 0.024 15.0 2.1 1.5 9.1 0.7 2.4 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 AAAP01003740.1_12 - 0.039 13.3 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 AAAP01003740.1_12 - 0.04 13.6 0.7 10 5.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 AAAP01003740.1_12 - 0.046 12.8 0.0 0.74 8.9 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 AAAP01003740.1_12 - 0.068 13.7 0.0 14 6.2 0.0 3.0 2 1 0 2 2 2 0 ABC transporter Rad17 PF03215.15 AAAP01003740.1_12 - 0.098 12.6 0.1 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 AAAP01003740.1_12 - 0.11 12.3 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 AAAP01003740.1_12 - 0.13 11.7 0.3 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 AAAP01003740.1_12 - 0.14 12.1 0.0 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DEAD PF00270.29 AAAP01003740.1_12 - 0.17 11.6 0.5 12 5.6 0.0 2.8 3 1 0 3 3 2 0 DEAD/DEAH box helicase DUF815 PF05673.13 AAAP01003740.1_12 - 0.18 11.0 0.0 6.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 AAAP01003740.1_12 - 0.2 11.0 0.0 20 4.5 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein Cytidylate_kin2 PF13189.6 AAAP01003740.1_12 - 0.21 11.7 0.0 0.95 9.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF3659 PF12396.8 AAAP01003741.1_4 - 0.0045 16.9 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) PALP PF00291.25 AAAP01003741.1_5 - 1.7e-46 159.0 0.5 2.2e-46 158.6 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AsmA PF05170.14 AAAP01003741.1_6 - 1.2e-25 90.5 4.0 7.1e-19 68.1 3.0 3.4 3 2 1 4 4 4 2 AsmA family AsmA_2 PF13502.6 AAAP01003741.1_6 - 1.1e-24 87.2 20.3 2.7e-16 59.8 5.9 5.4 4 2 1 5 5 5 3 AsmA-like C-terminal region DUF748 PF05359.11 AAAP01003741.1_6 - 0.0051 17.0 8.6 0.16 12.2 0.2 4.7 4 1 1 5 5 5 2 Domain of Unknown Function (DUF748) Hexapep PF00132.24 AAAP01003741.1_8 - 1.5e-13 49.9 16.6 1.2e-05 24.8 0.8 3.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003741.1_8 - 0.024 14.4 2.3 0.024 14.4 2.3 4.0 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Semialdhyde_dhC PF02774.18 AAAP01003741.1_9 - 2.1e-20 73.6 0.0 2.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AAAP01003741.1_9 - 1.1e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.28 AAAP01003742.1_1 - 1.7e-13 50.0 0.7 5.2e-13 48.4 0.7 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 AAAP01003742.1_1 - 9e-13 48.4 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Succ_CoA_lig PF13607.6 AAAP01003742.1_2 - 6e-33 113.6 0.3 1.7e-32 112.1 0.1 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAAP01003742.1_2 - 2.8e-14 53.6 0.2 8.3e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 AAAP01003742.1_2 - 0.038 14.8 0.0 2.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DmsC PF04976.12 AAAP01003742.1_3 - 9.9e-06 25.2 4.5 9.9e-06 25.2 4.5 2.2 1 1 1 2 2 2 1 DMSO reductase anchor subunit (DmsC) NrfD PF03916.14 AAAP01003742.1_3 - 3.4e-05 23.7 19.9 0.0033 17.1 10.6 2.0 1 1 1 2 2 2 2 Polysulphide reductase, NrfD Fer4_7 PF12838.7 AAAP01003742.1_4 - 1.6e-15 57.4 22.4 1.6e-06 28.6 2.4 3.2 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_11 PF13247.6 AAAP01003742.1_4 - 2.9e-15 56.2 18.6 4.2e-11 42.8 7.1 3.6 2 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003742.1_4 - 3.6e-13 49.4 19.7 9.4e-09 35.3 1.3 3.3 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003742.1_4 - 4.6e-12 45.9 17.4 4e-06 26.9 2.9 2.7 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003742.1_4 - 4.4e-09 35.9 35.9 9.9e-06 25.4 1.4 4.4 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003742.1_4 - 2.4e-08 33.5 14.2 1.4e-07 31.1 4.7 5.1 6 0 0 6 6 6 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003742.1_4 - 2.3e-07 31.7 20.0 0.0036 18.2 2.3 4.2 4 0 0 4 4 4 3 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAAP01003742.1_4 - 1.4e-06 28.8 18.1 0.0012 19.3 2.1 4.0 4 0 0 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003742.1_4 - 2.5e-06 27.3 4.2 2.5e-06 27.3 4.2 4.5 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003742.1_4 - 7.1e-06 26.4 20.0 0.0019 18.6 1.5 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003742.1_4 - 7e-05 23.0 32.7 0.015 15.7 2.3 4.7 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003742.1_4 - 9.4e-05 23.1 36.0 0.07 14.1 4.7 4.4 4 1 0 4 4 4 4 4Fe-4S binding domain Fer4_15 PF13459.6 AAAP01003742.1_4 - 0.0039 17.9 12.1 0.004 17.9 1.1 3.0 3 1 0 3 3 3 2 4Fe-4S single cluster domain Fer4_21 PF14697.6 AAAP01003742.1_4 - 0.011 15.9 4.9 0.011 15.9 4.9 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003742.1_4 - 1.2 10.1 24.2 0.15 12.9 2.1 4.0 2 1 3 5 5 5 0 4Fe-4S dicluster domain Molydop_binding PF01568.21 AAAP01003742.1_5 - 6.7e-10 39.0 0.1 8.2e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdopterin PF00384.22 AAAP01003742.1_6 - 1.7e-09 37.2 0.0 3.7e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molybdopterin PF00384.22 AAAP01003742.1_7 - 5e-14 52.1 0.0 8.1e-14 51.4 0.0 1.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 AAAP01003742.1_7 - 0.022 14.8 0.2 0.042 13.8 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain 4HBT PF03061.22 AAAP01003742.1_8 - 0.00078 19.8 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily NTS PF15447.6 AAAP01003742.1_8 - 0.027 15.0 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 GAPES3 PF17154.4 AAAP01003743.1_1 - 0.003 17.5 5.2 9 6.3 0.1 4.1 4 0 0 4 4 4 3 Gammaproteobacterial periplasmic sensor domain He_PIG PF05345.12 AAAP01003743.1_2 - 3.9e-07 30.2 0.1 1.1e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 Putative Ig domain Big_9 PF17963.1 AAAP01003743.1_2 - 0.00043 21.0 0.4 0.0015 19.2 0.1 1.9 2 0 0 2 2 2 1 Bacterial Ig domain Cadherin_5 PF17892.1 AAAP01003743.1_2 - 0.0015 18.4 0.0 0.0035 17.3 0.0 1.6 1 1 0 1 1 1 1 Cadherin-like domain HlyD_3 PF13437.6 AAAP01003743.1_3 - 3.8e-15 56.5 0.6 1.2e-13 51.6 0.1 2.4 2 1 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003743.1_3 - 1.3e-13 50.7 0.3 1.6e-13 50.4 0.3 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003743.1_3 - 2.5e-10 40.0 1.2 3.7e-05 23.5 0.0 3.3 3 1 1 4 4 4 2 Biotin-lipoyl like T2SSN PF01203.19 AAAP01003743.1_3 - 0.004 17.4 0.8 0.0068 16.6 0.8 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein N Biotin_lipoyl PF00364.22 AAAP01003743.1_3 - 0.0095 15.8 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 AAAP01003743.1_3 - 0.035 13.9 2.3 0.056 13.3 2.3 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein AlaDh_PNT_N PF05222.15 AAAP01003743.1_3 - 0.037 14.3 0.5 8.6 6.7 0.0 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain LcnG-beta PF11632.8 AAAP01003743.1_3 - 0.2 11.7 0.5 0.38 10.8 0.5 1.4 1 0 0 1 1 1 0 Lactococcin G-beta HlyD_3 PF13437.6 AAAP01003743.1_4 - 3.2e-19 69.6 2.4 1.9e-12 47.8 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003743.1_4 - 4.7e-11 42.3 0.2 7.3e-11 41.7 0.2 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003743.1_4 - 4.1e-08 32.9 0.4 1.1e-07 31.5 0.4 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003743.1_4 - 0.0021 17.9 0.1 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_3 PF13437.6 AAAP01003743.1_5 - 9.5e-09 35.9 0.3 2.8e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01003743.1_5 - 1.4e-07 31.2 0.0 3.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AAAP01003743.1_5 - 4.6e-06 26.0 0.0 3.2e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AAAP01003743.1_5 - 0.001 18.9 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Peptidase_M50 PF02163.22 AAAP01003743.1_5 - 0.47 9.7 11.1 5.8 6.1 11.1 2.4 1 1 0 1 1 1 0 Peptidase family M50 DUF5527 PF17665.1 AAAP01003743.1_6 - 0.092 12.3 0.2 0.097 12.2 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5527) Response_reg PF00072.24 AAAP01003743.1_7 - 1.4e-25 89.6 0.0 2.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003743.1_7 - 1.2e-05 25.2 1.7 2.1e-05 24.5 0.9 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain FlpD PF02662.16 AAAP01003744.1_1 - 1.1e-13 51.2 0.0 4.6e-13 49.3 0.0 1.9 1 1 1 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Fer4_6 PF12837.7 AAAP01003744.1_1 - 1.2e-08 34.6 11.1 0.00028 20.8 2.6 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003744.1_1 - 4.7e-08 33.5 8.1 1.4e-07 32.0 8.1 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003744.1_1 - 1.7e-07 30.7 16.9 1.6e-05 24.5 3.3 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003744.1_1 - 1.4e-06 28.4 7.6 3.7e-06 27.0 7.6 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003744.1_1 - 1.7e-06 28.1 3.8 0.014 15.5 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003744.1_1 - 3.5e-06 27.4 3.7 0.018 15.6 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003744.1_1 - 2.9e-05 24.1 10.7 0.0015 18.6 11.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003744.1_1 - 6.8e-05 22.7 12.1 0.015 15.3 3.1 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003744.1_1 - 0.00018 21.9 10.8 0.031 14.7 13.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003744.1_1 - 0.00056 20.2 12.8 0.13 12.8 3.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Cytochrom_B_C PF00032.17 AAAP01003744.1_1 - 0.089 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Fer4_22 PF17179.4 AAAP01003744.1_1 - 0.11 13.4 6.9 0.83 10.5 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003744.1_1 - 0.13 13.2 12.0 55 4.8 12.0 2.5 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AAAP01003744.1_1 - 2.1 9.1 11.2 5.3 7.9 0.4 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain COX1 PF00115.20 AAAP01003744.1_3 - 6.4e-09 35.2 14.4 7.7e-09 34.9 14.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 AAAP01003744.1_4 - 6.9e-07 28.5 9.5 6.9e-07 28.5 9.5 1.7 1 1 1 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 AAAP01003744.1_5 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Glyco_hydro_1 PF00232.18 AAAP01003744.1_6 - 4.9e-143 476.8 0.0 5.6e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AAAP01003744.1_6 - 0.02 14.3 0.0 0.054 12.9 0.0 1.6 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ABC_membrane_2 PF06472.15 AAAP01003744.1_7 - 1.3e-42 146.1 0.0 1.6e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 AAAP01003744.1_7 - 7e-19 68.4 0.2 1e-18 67.9 0.2 1.1 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 AAAP01003744.1_7 - 7.1e-05 23.3 0.0 0.00018 22.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAAP01003744.1_7 - 0.011 15.3 2.1 0.33 10.5 0.3 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region FtsX PF02687.21 AAAP01003744.1_7 - 0.41 11.1 11.1 0.11 13.0 0.6 2.9 3 0 0 3 3 3 0 FtsX-like permease family Peptidase_S11 PF00768.20 AAAP01003744.1_8 - 7e-53 179.5 0.0 9.2e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAAP01003744.1_8 - 5.7e-09 35.9 0.0 7.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AAAP01003744.1_8 - 0.0049 15.6 0.2 0.013 14.3 0.0 1.6 2 0 0 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family CHASE2 PF05226.11 AAAP01003744.1_10 - 9e-32 110.8 0.3 1.4e-31 110.1 0.3 1.2 1 0 0 1 1 1 1 CHASE2 domain Guanylate_cyc PF00211.20 AAAP01003744.1_10 - 1.7e-31 109.2 0.0 3.1e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_6 PF13174.6 AAAP01003744.1_10 - 0.1 13.3 0.1 0.34 11.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003744.1_11 - 5.5e-16 57.9 4.5 0.023 14.6 0.1 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003744.1_11 - 2.5e-14 53.3 12.3 2.7e-06 27.6 2.3 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003744.1_11 - 0.002 18.0 3.6 0.29 11.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003744.1_11 - 0.016 15.4 7.1 11 6.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003744.1_11 - 0.022 15.3 1.1 0.022 15.3 1.1 5.8 2 1 4 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003744.1_11 - 0.037 14.2 9.8 12 6.3 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat NINJA_B PF16136.5 AAAP01003744.1_11 - 0.14 12.5 1.7 0.34 11.3 1.7 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal 14-3-3 PF00244.20 AAAP01003744.1_11 - 0.45 10.0 3.1 2.1 7.8 0.1 3.0 3 1 1 4 4 4 0 14-3-3 protein TPR_14 PF13428.6 AAAP01003744.1_11 - 2.7 9.0 22.6 2.3 9.2 0.1 5.7 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003744.1_12 - 1.5e-37 127.8 6.3 1.3e-13 51.0 1.6 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003744.1_12 - 2.2e-29 100.5 1.8 1.2e-08 34.6 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003744.1_12 - 7e-10 38.2 0.6 0.45 10.7 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003744.1_12 - 9.3e-10 39.0 2.5 0.0009 19.8 4.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003744.1_12 - 2.4e-09 36.6 2.0 0.093 13.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003744.1_12 - 6.5e-09 35.2 0.5 0.28 11.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003744.1_12 - 8.4e-08 31.8 0.5 0.71 10.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003744.1_12 - 7.8e-07 28.8 0.2 1.1e-06 28.3 0.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 AAAP01003744.1_12 - 1.1e-06 29.0 3.2 0.0011 19.4 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003744.1_12 - 0.00014 22.0 0.6 4.9 7.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003744.1_12 - 0.0004 21.0 5.3 0.12 13.2 1.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003744.1_12 - 0.005 17.3 0.0 1.1 10.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4404 PF14357.6 AAAP01003744.1_12 - 0.01 16.4 0.1 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF348 PF03990.14 AAAP01003744.1_12 - 0.02 14.6 0.1 0.8 9.5 0.0 2.7 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain RPN6_N PF18055.1 AAAP01003744.1_12 - 0.1 12.9 0.2 0.21 12.0 0.1 1.5 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF2126 PF09899.9 AAAP01003745.1_2 - 0 1292.5 0.0 0 1292.2 0.0 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) Bact_transglu_N PF08379.10 AAAP01003745.1_2 - 5.4e-30 104.1 0.7 1.9e-29 102.4 0.7 2.0 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AAAP01003745.1_2 - 6.1e-19 68.5 0.0 2.6e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAAP01003745.1_2 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain CP_ATPgrasp_2 PF14403.6 AAAP01003745.1_3 - 7.3e-150 499.1 0.0 1.3e-149 498.3 0.0 1.4 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAAP01003745.1_3 - 3.8e-111 371.3 0.0 5.8e-111 370.7 0.0 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Alpha-E PF04168.12 AAAP01003745.1_3 - 3.6e-65 220.6 4.4 5.5e-65 220.0 4.4 1.3 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Bact_transglu_N PF08379.10 AAAP01003745.1_4 - 2e-24 86.3 0.5 2.6e-24 85.9 0.5 1.2 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transketolase_N PF00456.21 AAAP01003746.1_1 - 1.9e-97 326.2 0.3 2.2e-97 326.0 0.3 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AAAP01003746.1_1 - 6.4e-06 25.6 0.1 9.7e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAAP01003746.1_1 - 0.00076 19.3 0.4 0.0016 18.2 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AAAP01003746.1_1 - 0.0026 16.8 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PSD2 PF07624.11 AAAP01003746.1_1 - 0.18 11.6 0.1 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) FBPase_glpX PF03320.13 AAAP01003746.1_2 - 2.7e-112 374.6 2.0 3.1e-112 374.4 2.0 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded AcetylCoA_hyd_C PF13336.6 AAAP01003746.1_3 - 1.7e-39 135.2 0.0 3e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 AAAP01003746.1_3 - 2.6e-29 102.6 0.1 6e-29 101.4 0.0 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.12 AAAP01003746.1_3 - 1.1e-07 31.1 3.2 2.9e-07 29.7 1.3 2.4 2 1 1 3 3 3 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 AAAP01003746.1_3 - 0.00081 18.8 0.1 0.0017 17.8 0.1 1.6 1 1 0 1 1 1 1 Coenzyme A transferase Tafi-CsgC PF10610.9 AAAP01003746.1_3 - 0.043 14.0 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein AsnC_trans_reg PF01037.21 AAAP01003746.1_4 - 5.4e-15 55.1 0.1 6e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain Helicase_C PF00271.31 AAAP01003746.1_5 - 4.7e-13 49.5 0.2 7.8e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAAP01003746.1_6 - 2.8e-52 177.0 0.0 4.7e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01003746.1_6 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAAP01003746.1_6 - 2.1e-05 24.9 0.0 7.4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PRAI PF00697.22 AAAP01003746.1_6 - 0.0081 15.9 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase AAA_22 PF13401.6 AAAP01003746.1_6 - 0.085 13.1 1.6 1 9.6 1.6 2.5 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 AAAP01003746.1_6 - 0.092 12.6 0.0 0.44 10.4 0.0 2.0 1 1 1 2 2 2 0 Helicase Isochorismatase PF00857.20 AAAP01003746.1_7 - 5.3e-28 98.4 0.0 7.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Orn_Arg_deC_N PF02784.16 AAAP01003746.1_8 - 2e-54 184.6 0.0 2.5e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAAP01003746.1_8 - 9.6e-10 38.6 0.0 9.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAAP01003746.1_8 - 0.00031 20.5 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Flg_bb_rod PF00460.20 AAAP01003746.1_9 - 0.00019 21.2 0.5 0.00019 21.2 0.5 2.1 2 0 0 2 2 2 1 Flagella basal body rod protein CutA1 PF03091.15 AAAP01003747.1_2 - 1.4e-38 130.7 0.3 1.6e-38 130.5 0.3 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DEP PF00610.21 AAAP01003747.1_2 - 0.014 15.4 0.0 0.031 14.3 0.0 1.6 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IspD PF01128.19 AAAP01003747.1_3 - 2.5e-63 213.8 1.2 3.4e-63 213.3 1.2 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YgbB PF02542.16 AAAP01003747.1_3 - 6.7e-61 205.1 0.0 4.1e-60 202.5 0.0 1.9 2 0 0 2 2 2 1 YgbB family NTP_transf_3 PF12804.7 AAAP01003747.1_3 - 2.1e-10 41.2 2.1 3.3e-10 40.6 2.1 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Cytochrom_C_asm PF01578.20 AAAP01003747.1_4 - 1.9e-15 57.3 15.7 2.7e-15 56.7 15.7 1.3 1 0 0 1 1 1 1 Cytochrome C assembly protein Dus PF01207.17 AAAP01003747.1_5 - 2.7e-109 365.0 0.2 3.4e-109 364.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AAAP01003747.1_5 - 7.1e-06 25.4 0.6 0.0057 15.9 0.1 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AAAP01003747.1_5 - 0.01 15.3 1.1 0.023 14.1 0.6 1.8 2 1 0 2 2 2 0 Histidine biosynthesis protein PEP_mutase PF13714.6 AAAP01003747.1_5 - 0.03 13.8 0.5 0.094 12.1 0.0 2.0 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase HATPase_c PF02518.26 AAAP01003747.1_6 - 8.3e-19 68.2 0.0 1.4e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003747.1_6 - 1.7e-12 47.2 0.2 5e-12 45.7 0.1 1.9 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003747.1_6 - 1.8e-10 40.8 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003747.1_6 - 7.1e-07 29.5 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003747.1_6 - 0.0038 17.5 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003747.1_6 - 0.012 15.7 0.0 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 PAS domain HATPase_c_5 PF14501.6 AAAP01003747.1_6 - 0.012 15.5 0.0 0.033 14.1 0.0 1.7 1 1 0 1 1 1 0 GHKL domain Sigma54_activat PF00158.26 AAAP01003747.1_7 - 4.6e-71 237.9 0.0 7.3e-71 237.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01003747.1_7 - 1.7e-27 96.2 0.0 6.6e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAAP01003747.1_7 - 6.7e-26 90.7 0.0 1.5e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AAAP01003747.1_7 - 8.8e-14 51.0 0.6 2.6e-13 49.5 0.3 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAAP01003747.1_7 - 6.4e-09 35.9 0.0 1.6e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01003747.1_7 - 5.4e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01003747.1_7 - 8.7e-06 26.2 0.2 2.2e-05 24.9 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 AAAP01003747.1_7 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Phage_NinH PF06322.11 AAAP01003747.1_7 - 0.00073 19.4 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Phage NinH protein Mg_chelatase PF01078.21 AAAP01003747.1_7 - 0.011 15.1 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAAP01003747.1_7 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AAAP01003747.1_7 - 0.053 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain AAA_7 PF12775.7 AAAP01003747.1_7 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HAMP PF00672.25 AAAP01003747.1_8 - 8.8e-14 51.6 0.6 8.8e-14 51.6 0.6 2.3 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAAP01003747.1_8 - 6.2e-10 39.0 0.0 3.8e-09 36.5 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003747.1_8 - 1.2e-08 35.2 0.1 2.7e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003747.1_8 - 5.1e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003747.1_8 - 2.2e-06 27.9 0.0 7.2e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 AAAP01003747.1_8 - 0.0017 18.5 0.0 0.0063 16.7 0.0 2.1 1 1 0 1 1 1 1 PAS fold P22_CoatProtein PF11651.8 AAAP01003747.1_8 - 0.013 14.1 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Virul_fac_BrkB PF03631.15 AAAP01003747.1_8 - 0.026 14.1 5.7 1.7 8.2 0.0 3.0 2 1 0 2 2 2 0 Virulence factor BrkB HigB-like_toxin PF05015.13 AAAP01003748.1_1 - 0.044 14.2 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB OprB PF04966.12 AAAP01003748.1_2 - 1.7e-11 44.2 0.1 2e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Cytochrom_B562 PF07361.11 AAAP01003748.1_4 - 0.11 13.1 0.4 0.99 10.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome b562 DUF29 PF01724.16 AAAP01003748.1_8 - 0.0039 17.4 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF29 Response_reg PF00072.24 AAAP01003748.1_9 - 3.7e-23 81.8 0.0 4.1e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain 3HCDH_RFF PF18321.1 AAAP01003748.1_9 - 0.052 14.0 0.2 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain UCR_UQCRX_QCR9 PF05365.12 AAAP01003748.1_12 - 0.023 14.6 0.3 0.065 13.2 0.0 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like FLgD_tudor PF13861.6 AAAP01003748.1_13 - 0.54 10.5 24.3 0.54 10.5 1.8 3.3 3 0 0 3 3 3 0 FlgD Tudor-like domain PsbW PF07123.12 AAAP01003748.1_15 - 0.3 11.1 3.1 0.36 10.9 3.1 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) FeoB_associated PF12669.7 AAAP01003748.1_16 - 2.9e-05 24.4 4.6 4.4e-05 23.8 4.6 1.4 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein Plasmid_RAQPRD PF09686.10 AAAP01003748.1_19 - 0.29 11.4 2.0 1.4 9.2 2.0 2.2 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MCPsignal PF00015.21 AAAP01003749.1_1 - 4.7e-34 117.7 36.0 8.7e-33 113.5 26.1 3.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003749.1_1 - 0.00069 19.8 13.1 0.86 9.9 1.1 3.7 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003749.1_1 - 0.0011 19.0 9.6 0.93 9.5 0.6 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) DUF3450 PF11932.8 AAAP01003749.1_1 - 0.047 13.0 8.1 0.016 14.5 0.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DHR10 PF18595.1 AAAP01003749.1_1 - 0.061 13.4 4.6 0.14 12.2 0.2 3.0 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Sec5 PF15469.6 AAAP01003749.1_1 - 0.17 11.7 0.0 0.78 9.5 0.0 1.9 1 1 1 2 2 2 0 Exocyst complex component Sec5 Laminin_II PF06009.12 AAAP01003749.1_1 - 0.27 11.3 14.5 4.2 7.4 3.3 3.4 1 1 1 3 3 3 0 Laminin Domain II Laminin_I PF06008.14 AAAP01003749.1_1 - 0.83 9.3 17.9 3.4 7.3 3.6 3.5 1 1 3 4 4 4 0 Laminin Domain I Vps53_N PF04100.12 AAAP01003749.1_1 - 1 8.3 8.1 0.18 10.8 1.5 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal TraG_N PF07916.11 AAAP01003749.1_1 - 1.3 7.8 7.7 0.63 8.8 3.4 2.0 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Seryl_tRNA_N PF02403.22 AAAP01003749.1_1 - 2 8.7 5.4 8.6 6.6 0.3 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ISG65-75 PF11727.8 AAAP01003749.1_1 - 2.2 7.5 13.4 2.9 7.1 3.1 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein GATase PF00117.28 AAAP01003749.1_2 - 2.7e-13 50.1 0.0 3.8e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01003749.1_2 - 4.3e-05 23.4 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AAAP01003749.1_2 - 0.039 13.7 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.14 AAAP01003749.1_2 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF2336 PF10098.9 AAAP01003749.1_3 - 3.6e-82 275.8 12.1 4.3e-82 275.5 3.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2336) Skp1 PF01466.19 AAAP01003749.1_3 - 0.095 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, dimerisation domain F-box_4 PF15966.5 AAAP01003749.1_4 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box Response_reg PF00072.24 AAAP01003749.1_5 - 8.2e-21 74.3 0.1 9.6e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003749.1_6 - 5e-19 68.9 0.0 1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE PF03924.13 AAAP01003749.1_6 - 5.2e-08 33.1 0.1 1.8e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 CHASE domain HisKA PF00512.25 AAAP01003749.1_6 - 4.7e-06 26.5 0.1 1.5e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003749.1_6 - 0.05 13.6 0.0 0.86 9.6 0.0 2.8 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain DUF5086 PF16985.5 AAAP01003749.1_6 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) HMGL-like PF00682.19 AAAP01003749.1_7 - 2.6e-74 250.1 0.0 1.3e-73 247.9 0.0 1.8 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 AAAP01003749.1_7 - 2e-28 98.9 0.7 4.1e-28 97.9 0.1 1.8 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain EAL PF00563.20 AAAP01003749.1_8 - 9.6e-70 234.8 0.2 6.9e-68 228.7 0.2 2.5 1 1 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003749.1_8 - 3e-41 140.8 0.0 5.3e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003749.1_8 - 1.1e-16 60.9 0.0 2.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003749.1_8 - 6.2e-13 48.7 0.0 2.7e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AAAP01003749.1_8 - 4.6e-09 36.1 0.0 1.9e-07 31.0 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 AAAP01003749.1_8 - 2.4e-08 34.1 0.0 6.6e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AAAP01003749.1_8 - 2.9e-06 27.6 1.8 5.1e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 HAMP domain PAS_4 PF08448.10 AAAP01003749.1_8 - 5.7e-06 26.5 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold CTP_transf_like PF01467.26 AAAP01003750.1_1 - 4.5e-16 59.3 0.0 7.3e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AAAP01003750.1_1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DNA_topoisoIV PF00521.20 AAAP01003750.1_2 - 3.5e-151 503.9 0.0 4.5e-151 503.6 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AAAP01003750.1_2 - 4.3e-71 234.2 14.2 5.6e-15 54.5 0.2 7.2 7 0 0 7 7 7 6 DNA gyrase C-terminal domain, beta-propeller Leucyl-specific PF14795.6 AAAP01003750.1_2 - 0.16 12.1 0.3 9.5 6.4 0.1 2.7 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain HlyD_3 PF13437.6 AAAP01003750.1_3 - 4.9e-17 62.6 2.3 5.4e-15 56.0 0.1 3.2 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003750.1_3 - 5.3e-06 25.8 11.3 6.2e-06 25.6 2.6 2.6 1 1 2 3 3 3 3 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAAP01003750.1_3 - 2.9e-05 23.9 0.1 3.9e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAAP01003750.1_3 - 0.00042 20.1 6.3 0.046 13.6 0.2 3.9 3 2 1 4 4 4 2 Biotin-requiring enzyme CSD2 PF17876.1 AAAP01003750.1_3 - 0.016 15.4 0.1 0.12 12.6 0.2 2.5 3 0 0 3 3 3 0 Cold shock domain BLOC1_2 PF10046.9 AAAP01003750.1_3 - 0.054 13.8 2.9 0.18 12.1 0.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 S1 PF00575.23 AAAP01003750.1_3 - 0.14 12.5 1.2 0.76 10.2 1.2 2.3 1 1 0 1 1 1 0 S1 RNA binding domain Biotin_lipoyl_2 PF13533.6 AAAP01003750.1_3 - 0.37 10.6 7.3 0.23 11.3 0.5 3.4 3 1 0 3 3 3 0 Biotin-lipoyl like ABC_membrane PF00664.23 AAAP01003750.1_4 - 1.2e-23 84.2 10.3 1.8e-23 83.6 10.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003750.1_4 - 2e-18 67.2 0.0 3.4e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01003750.1_4 - 0.00034 20.3 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01003750.1_4 - 0.00074 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 AAAP01003750.1_4 - 0.00076 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_15 PF13175.6 AAAP01003750.1_4 - 0.0025 17.6 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAAP01003750.1_4 - 0.0069 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AAAP01003750.1_4 - 0.019 14.3 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 AAAP01003750.1_4 - 0.024 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C39 PF03412.15 AAAP01003750.1_4 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family AAA_16 PF13191.6 AAAP01003750.1_4 - 0.1 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 AAAP01003750.1_4 - 0.13 11.7 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 AAAP01003750.1_5 - 1.5e-26 93.7 7.2 2.2e-26 93.1 7.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003750.1_5 - 4.1e-26 92.1 0.0 6.3e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 AAAP01003750.1_5 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003750.1_5 - 0.0026 17.5 0.1 0.0081 15.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003750.1_5 - 0.013 16.0 0.4 0.022 15.3 0.4 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003750.1_5 - 0.02 14.8 0.0 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 AAAP01003750.1_5 - 0.02 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 AAAP01003750.1_5 - 0.034 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DLIC PF05783.11 AAAP01003750.1_5 - 0.038 12.8 0.1 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_28 PF13521.6 AAAP01003750.1_5 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01003750.1_5 - 0.17 12.3 0.1 0.49 10.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003750.1_5 - 0.18 11.5 0.1 0.43 10.3 0.1 1.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 AAAP01003750.1_5 - 0.25 11.1 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAAP01003750.1_5 - 0.29 10.8 0.0 0.39 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_M20 PF01546.28 AAAP01003750.1_6 - 1.3e-33 116.5 0.0 2.5e-33 115.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAAP01003750.1_6 - 5.3e-24 84.2 0.0 9.6e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 AAAP01003750.1_6 - 0.00021 21.1 0.0 0.00046 19.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 AAAP01003750.1_6 - 0.0014 17.7 0.0 0.16 10.9 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Big_9 PF17963.1 AAAP01003751.1_1 - 6.6e-72 238.3 155.1 1.4e-10 41.7 15.2 8.1 1 1 7 8 8 8 8 Bacterial Ig domain Cadherin_4 PF17803.1 AAAP01003751.1_1 - 9.4e-67 221.6 132.6 1.2e-09 38.7 11.9 8.9 8 0 0 8 8 8 8 Bacterial cadherin-like domain Dioxygenase_C PF00775.21 AAAP01003751.1_1 - 5.8e-07 29.1 3.0 32 3.9 0.0 6.5 7 0 0 7 7 7 0 Dioxygenase Cadherin_5 PF17892.1 AAAP01003751.1_1 - 1.2e-06 28.4 94.2 0.37 10.8 7.2 8.2 7 0 0 7 7 7 6 Cadherin-like domain VLPT PF07122.11 AAAP01003751.1_1 - 1.8e-05 24.4 0.0 96 2.8 0.0 6.4 7 0 0 7 7 7 0 Variable length PCR target protein (VLPT) DUF4493 PF14900.6 AAAP01003751.1_1 - 5e-05 23.3 46.9 1.2 9.0 1.5 7.2 7 0 0 7 7 7 7 Domain of unknown function (DUF4493) YfkB PF08756.10 AAAP01003751.1_1 - 0.00064 19.5 0.7 1.5e+02 2.1 0.0 5.9 7 0 0 7 7 7 0 YfkB-like domain Tocopherol_cycl PF14249.6 AAAP01003751.1_1 - 0.00095 18.4 11.0 19 4.3 0.0 6.2 1 1 6 7 7 7 0 Tocopherol cyclase NIDO PF06119.14 AAAP01003751.1_1 - 0.028 15.4 26.0 75 4.4 0.1 9.0 8 6 0 8 8 8 0 Nidogen-like Bac_rhamnosid_N PF08531.10 AAAP01003751.1_1 - 0.069 13.0 18.0 88 2.9 0.1 7.0 7 0 0 7 7 7 0 Alpha-L-rhamnosidase N-terminal domain Chitin_bind_4 PF00379.23 AAAP01003751.1_1 - 2.9 8.5 25.9 1.5e+02 3.0 0.0 8.7 7 5 0 7 7 7 0 Insect cuticle protein Cadherin_5 PF17892.1 AAAP01003751.1_2 - 1.4e-93 307.2 33.9 8e-34 115.5 4.4 16.0 17 1 0 17 17 17 9 Cadherin-like domain Big_9 PF17963.1 AAAP01003751.1_2 - 2.1e-80 265.5 282.9 2.2e-18 66.8 10.8 17.3 7 3 5 14 14 14 9 Bacterial Ig domain HemolysinCabind PF00353.19 AAAP01003751.1_2 - 7.9e-77 252.6 261.9 1.3e-11 44.2 17.3 20.0 17 5 1 18 18 18 18 RTX calcium-binding nonapeptide repeat (4 copies) Cadherin_4 PF17803.1 AAAP01003751.1_2 - 3.7e-65 216.5 161.0 2.4e-14 53.7 9.0 16.4 12 2 1 14 14 14 9 Bacterial cadherin-like domain GldM_C PF12080.8 AAAP01003751.1_2 - 0.064 13.5 14.0 2.4 8.4 0.1 5.9 5 0 0 5 5 5 0 GldM C-terminal domain Tocopherol_cycl PF14249.6 AAAP01003751.1_2 - 0.15 11.2 3.3 56 2.7 0.0 4.1 1 1 3 4 4 4 0 Tocopherol cyclase HU-CCDC81_bac_2 PF18175.1 AAAP01003751.1_2 - 2.3 8.2 3.7 89 3.1 0.0 4.2 5 0 0 5 5 5 0 CCDC81-like prokaryotic HU domain 2 DUF5643 PF18705.1 AAAP01003751.1_2 - 6.9 6.7 16.4 1.4 8.9 0.0 6.0 5 0 0 5 5 5 0 Family of unknown function (DUF5643) Big_9 PF17963.1 AAAP01003751.1_3 - 1.7e-30 105.6 68.4 7.1e-16 58.7 12.4 4.4 4 0 0 4 4 4 4 Bacterial Ig domain Cadherin_5 PF17892.1 AAAP01003751.1_3 - 2.1e-15 56.5 8.6 2.1e-15 56.5 8.6 5.4 3 3 1 4 4 4 2 Cadherin-like domain Cadherin_4 PF17803.1 AAAP01003751.1_3 - 4.3e-14 52.9 68.2 7.4e-05 23.3 15.9 5.2 4 2 0 4 4 4 3 Bacterial cadherin-like domain DUF4114 PF13448.6 AAAP01003751.1_3 - 0.011 16.5 3.9 0.013 16.3 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4114) DUF4369 PF14289.6 AAAP01003751.1_3 - 0.043 14.3 7.8 3.2 8.3 1.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4369) DUF5643 PF18705.1 AAAP01003751.1_3 - 0.17 11.8 8.4 1.3 9.1 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5643) YmzC PF14157.6 AAAP01003751.1_3 - 4.6 7.4 11.1 2.1 8.5 0.9 3.1 3 0 0 3 3 3 0 YmzC-like protein DUF4436 PF14494.6 AAAP01003751.1_3 - 7.4 5.8 8.1 8.3 5.6 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4436) DUF5012 PF16404.5 AAAP01003752.1_1 - 0.017 15.2 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) UnbV_ASPIC PF07593.12 AAAP01003752.1_1 - 0.044 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV DNA_ligase_aden PF01653.18 AAAP01003752.1_2 - 1e-108 363.2 0.0 1.3e-108 362.8 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AAAP01003752.1_2 - 1.2e-34 118.1 4.0 2.3e-34 117.1 4.0 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 AAAP01003752.1_2 - 4.9e-18 65.0 0.1 1.2e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif BRCT PF00533.26 AAAP01003752.1_2 - 4.5e-13 49.4 0.0 1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 AAAP01003752.1_2 - 4.7e-11 42.5 5.1 1.1e-10 41.3 5.1 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain HHH_5 PF14520.6 AAAP01003752.1_2 - 3.4e-06 27.5 0.0 0.0011 19.6 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 AAAP01003752.1_2 - 0.014 15.4 0.3 0.034 14.1 0.1 1.8 2 0 0 2 2 2 0 twin BRCT domain HHH PF00633.23 AAAP01003752.1_2 - 0.031 14.2 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_11 PF13414.6 AAAP01003752.1_3 - 0.031 14.0 1.0 7.2 6.4 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 AAAP01003752.1_3 - 0.033 14.0 9.4 3.6 7.6 0.1 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003752.1_3 - 0.036 14.4 7.6 2 8.7 0.0 4.6 2 2 3 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 AAAP01003752.1_3 - 0.049 13.0 0.4 6.6 6.1 0.0 2.7 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 AAAP01003752.1_3 - 0.06 13.5 5.1 40 4.7 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat GP46 PF07409.12 AAAP01003752.1_3 - 0.12 12.1 0.1 0.9 9.3 0.0 2.3 3 0 0 3 3 3 0 Phage protein GP46 GTP_EFTU PF00009.27 AAAP01003752.1_4 - 1.2e-51 175.1 0.2 1.7e-51 174.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 AAAP01003752.1_4 - 1.5e-08 34.9 0.2 2.9e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAAP01003752.1_4 - 7.4e-06 26.0 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 AAAP01003752.1_4 - 0.006 15.9 0.1 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Septin Ras PF00071.22 AAAP01003752.1_4 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Ras family MMR_HSR1_Xtn PF16897.5 AAAP01003752.1_4 - 0.036 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 AAAP01003752.1_4 - 0.13 11.7 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LepA_C PF06421.12 AAAP01003752.1_5 - 2.7e-51 172.2 0.3 3.5e-51 171.8 0.3 1.1 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AAAP01003752.1_5 - 1.5e-17 63.4 0.0 2.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF58 PF01882.18 AAAP01003752.1_6 - 9.6e-16 57.8 0.6 1.8e-15 57.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 TetR_C_31 PF17940.1 AAAP01003752.1_6 - 0.2 11.9 9.3 0.28 11.4 1.7 3.1 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain BatA PF07584.11 AAAP01003752.1_7 - 5.9e-14 52.2 15.7 1.2e-13 51.2 15.7 1.6 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal PNTB PF02233.16 AAAP01003753.1_1 - 1.8e-44 152.4 7.1 2.1e-44 152.2 7.1 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit SLATT_5 PF18160.1 AAAP01003753.1_1 - 0.27 10.5 0.4 0.51 9.6 0.1 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF981 PF06168.11 AAAP01003753.1_1 - 0.67 9.9 12.0 0.57 10.1 10.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 AAAP01003753.1_1 - 6.4 6.4 9.6 32 4.1 9.6 2.1 1 1 0 1 1 1 0 O-Antigen ligase AlaDh_PNT_C PF01262.21 AAAP01003753.1_2 - 9.8e-72 240.7 5.1 1.4e-71 240.2 5.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AAAP01003753.1_2 - 4.2e-50 169.6 0.0 9.8e-50 168.4 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 AAAP01003753.1_2 - 2.3e-34 117.7 5.6 2.3e-34 117.7 5.6 2.3 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF3392 PF11872.8 AAAP01003753.1_2 - 0.0059 16.9 2.5 0.014 15.6 2.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) 2-Hacid_dh_C PF02826.19 AAAP01003753.1_2 - 0.0059 16.0 1.0 2.3 7.6 0.2 3.2 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 AAAP01003753.1_2 - 1 9.3 5.8 1.3 9.0 1.5 2.9 2 2 1 3 3 3 0 Zinc-binding dehydrogenase DUF485 PF04341.12 AAAP01003753.1_2 - 3.3 7.7 5.0 3.3 7.7 3.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF485 DUF3108 PF11306.8 AAAP01003753.1_3 - 1.9e-15 57.5 0.0 2.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3108) MCPsignal PF00015.21 AAAP01003753.1_4 - 8.2e-37 126.7 13.9 8.2e-37 126.7 13.9 3.1 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_2 PF08269.11 AAAP01003753.1_4 - 4.1e-30 105.0 0.0 9.4e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Cache domain sCache_2 PF17200.4 AAAP01003753.1_4 - 6e-28 97.6 0.9 2.9e-13 49.9 0.1 2.9 2 0 0 2 2 2 2 Single Cache domain 2 CZB PF13682.6 AAAP01003753.1_4 - 2.6e-11 43.8 0.0 5.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain Cache_3-Cache_2 PF17201.4 AAAP01003753.1_4 - 0.00045 19.6 0.6 0.0015 17.8 0.0 2.3 2 2 0 2 2 2 1 Cache 3/Cache 2 fusion domain NPV_P10 PF05531.12 AAAP01003753.1_4 - 0.011 16.1 4.0 1.8 9.0 0.0 4.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TSKS PF15358.6 AAAP01003753.1_4 - 0.017 13.5 5.0 0.011 14.1 3.0 1.6 1 1 0 1 1 1 0 Testis-specific serine kinase substrate DUF1664 PF07889.12 AAAP01003753.1_4 - 0.021 14.9 6.2 5.7 7.0 0.0 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) HAMP PF00672.25 AAAP01003753.1_4 - 0.024 15.0 4.5 2.3 8.7 0.1 4.1 3 1 0 3 3 3 0 HAMP domain PT-TG PF14449.6 AAAP01003753.1_4 - 0.03 14.2 0.3 0.12 12.3 0.3 2.1 1 0 0 1 1 1 0 Pre-toxin TG COG6 PF06419.11 AAAP01003753.1_4 - 0.1 10.8 2.1 1.2 7.2 0.4 2.5 2 1 1 3 3 3 0 Conserved oligomeric complex COG6 DUF603 PF04645.12 AAAP01003753.1_4 - 0.22 11.2 1.9 12 5.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF603 DUF948 PF06103.11 AAAP01003753.1_4 - 0.34 11.2 13.1 4.2 7.7 0.5 4.8 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) FAA_hydrolase PF01557.18 AAAP01003753.1_5 - 2.5e-65 220.2 0.0 3.3e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TAT_signal PF10518.9 AAAP01003753.1_5 - 0.0022 17.8 7.7 0.0073 16.1 7.7 2.0 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Peptidase_M3 PF01432.20 AAAP01003753.1_6 - 7.4e-32 111.2 0.0 7.9e-31 107.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 AAAP01003753.1_6 - 2.5e-20 72.5 0.1 7.2e-20 71.0 0.1 1.9 1 0 0 1 1 1 1 Oligopeptidase F HEAT PF02985.22 AAAP01003753.1_6 - 0.031 14.5 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat AMP-binding PF00501.28 AAAP01003753.1_7 - 3.7e-57 193.8 0.0 4.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 AAAP01003753.1_8 - 5.9e-39 133.9 0.1 7.5e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003753.1_8 - 9.8e-05 23.3 0.0 0.00022 22.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Response_reg PF00072.24 AAAP01003753.1_9 - 5e-06 26.7 0.0 7.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain ABC2_membrane PF01061.24 AAAP01003754.1_1 - 1.6e-31 109.4 24.8 2e-31 109.0 24.8 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01003754.1_1 - 1.4e-16 60.5 24.3 1.8e-16 60.2 24.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AAAP01003754.1_1 - 2.9e-11 43.2 19.8 9.3e-11 41.5 19.8 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAAP01003754.1_1 - 0.0019 18.2 15.9 0.01 15.8 16.0 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AAAP01003754.1_1 - 0.0047 16.5 13.3 0.0064 16.1 13.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein BphX PF06139.12 AAAP01003754.1_1 - 0.24 11.3 7.0 0.099 12.6 3.6 1.9 1 1 1 2 2 2 0 BphX-like ABC_tran PF00005.27 AAAP01003754.1_2 - 2.1e-26 93.1 0.0 3.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003754.1_2 - 4e-10 40.0 0.8 0.00023 21.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003754.1_2 - 0.00016 21.2 0.0 0.063 12.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003754.1_2 - 0.00027 21.5 0.0 0.00046 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01003754.1_2 - 0.00035 20.3 0.6 0.67 9.6 0.0 2.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AAAP01003754.1_2 - 0.00053 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AAAP01003754.1_2 - 0.00091 18.9 1.1 0.015 14.9 0.3 2.7 2 1 0 2 2 2 1 AAA domain DUF4162 PF13732.6 AAAP01003754.1_2 - 0.0046 17.6 0.0 0.0085 16.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_18 PF13238.6 AAAP01003754.1_2 - 0.009 16.6 0.4 0.23 12.0 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01003754.1_2 - 0.01 15.6 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 AAAP01003754.1_2 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 AAAP01003754.1_2 - 0.018 15.4 0.3 0.052 13.9 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AAAP01003754.1_2 - 0.031 14.7 0.1 0.19 12.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AAAP01003754.1_2 - 0.031 14.2 0.0 0.12 12.2 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 AAAP01003754.1_2 - 0.038 14.0 0.6 0.28 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AAAP01003754.1_2 - 0.053 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 AAAP01003754.1_2 - 0.061 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003754.1_2 - 0.085 13.1 0.0 0.93 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 AAAP01003754.1_2 - 0.095 12.0 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 KaiC CLP1_P PF16575.5 AAAP01003754.1_2 - 0.16 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 AAAP01003754.1_2 - 0.17 12.0 0.6 0.49 10.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain GATase_3 PF07685.14 AAAP01003754.1_3 - 1.8e-32 112.6 0.0 2.5e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 AAAP01003754.1_3 - 2.4e-17 63.4 0.1 3e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 AAAP01003754.1_3 - 2e-15 57.0 0.0 3.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 AAAP01003754.1_3 - 0.013 15.4 0.0 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 AAAP01003754.1_3 - 0.13 11.8 0.3 0.36 10.4 0.3 1.7 1 0 0 1 1 1 0 AAA domain Glycos_trans_3N PF02885.17 AAAP01003754.1_4 - 1.7e-15 56.6 3.0 8e-15 54.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 AAAP01003754.1_4 - 1.7e-09 37.7 0.4 9.5e-09 35.2 0.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Methyltransf_25 PF13649.6 AAAP01003754.1_5 - 1.9e-20 73.4 0.1 3e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003754.1_5 - 5.7e-15 55.9 0.0 8.7e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003754.1_5 - 3.6e-13 50.0 0.1 5.5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003754.1_5 - 6e-13 48.9 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003754.1_5 - 7.8e-11 41.8 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AAAP01003754.1_5 - 2.9e-09 37.0 0.0 3.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003754.1_5 - 2.9e-06 26.8 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 AAAP01003754.1_5 - 7.2e-05 22.2 0.0 9.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 AAAP01003754.1_5 - 0.00024 20.9 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 AAAP01003754.1_5 - 0.00034 20.1 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 AAAP01003754.1_5 - 0.0008 19.0 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 AAAP01003754.1_5 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AAAP01003754.1_5 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 AAAP01003754.1_5 - 0.0076 15.4 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase DUF938 PF06080.12 AAAP01003754.1_5 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.19 AAAP01003754.1_5 - 0.04 13.7 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AAAP01003754.1_5 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Guanylate_cyc PF00211.20 AAAP01003754.1_7 - 2.6e-26 92.4 0.0 4.2e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 AAAP01003754.1_7 - 3.1e-24 86.1 0.0 6e-23 81.9 0.0 2.2 1 1 0 1 1 1 1 Cache domain Cache_3-Cache_2 PF17201.4 AAAP01003754.1_7 - 3.5e-05 23.2 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain HAMP PF00672.25 AAAP01003754.1_7 - 0.0029 17.9 1.6 0.0044 17.4 0.2 2.1 2 0 0 2 2 2 1 HAMP domain sCache_3_2 PF17203.4 AAAP01003754.1_7 - 0.0048 17.0 0.1 4.2 7.5 0.0 2.7 1 1 1 2 2 2 2 Single cache domain 3 TPR_2 PF07719.17 AAAP01003754.1_7 - 0.053 13.7 0.3 0.13 12.5 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CitMHS PF03600.16 AAAP01003755.1_2 - 1.3e-29 103.4 8.5 1.5e-29 103.2 8.5 1.1 1 0 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 AAAP01003755.1_2 - 8.7e-09 34.9 11.6 3.1e-06 26.5 4.5 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region TrkA_C PF02080.21 AAAP01003755.1_2 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain Fer2_BFD PF04324.15 AAAP01003755.1_3 - 5.6e-11 42.6 0.1 5.6e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain AMP-binding PF00501.28 AAAP01003755.1_4 - 4.2e-88 295.8 0.0 5.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003755.1_4 - 3.1e-21 76.1 0.1 6.2e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.6 AAAP01003755.1_6 - 0.00018 22.0 0.1 0.00033 21.1 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M3_N PF08439.10 AAAP01003755.1_6 - 0.018 15.3 0.1 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 Oligopeptidase F DUF1574 PF07611.11 AAAP01003755.1_6 - 0.054 12.8 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) MAF_flag10 PF01973.18 AAAP01003755.1_6 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 HIT PF01230.23 AAAP01003755.1_7 - 2.6e-12 47.3 0.0 3.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain Apolipoprotein PF01442.18 AAAP01003755.1_8 - 1.3e-13 51.3 103.7 8.4e-05 22.5 22.8 6.0 1 1 4 5 5 5 5 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.10 AAAP01003755.1_8 - 0.0054 17.0 12.1 0.009 16.3 3.0 10.2 3 2 7 11 11 11 3 Phasin protein Prominin PF05478.11 AAAP01003755.1_8 - 0.026 12.5 29.7 0.3 9.0 2.1 4.6 1 1 2 4 4 4 0 Prominin Baculo_PEP_C PF04513.12 AAAP01003755.1_8 - 0.12 12.5 45.3 0.072 13.1 5.5 7.9 1 1 5 7 7 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.12 AAAP01003755.1_8 - 0.2 11.7 16.1 0.33 11.1 0.0 5.5 5 0 0 5 5 5 0 Phage shock protein B Tup_N PF08581.10 AAAP01003755.1_8 - 0.23 11.8 0.1 0.23 11.8 0.1 5.7 6 1 1 7 7 6 0 Tup N-terminal Collagen_mid PF15984.5 AAAP01003755.1_8 - 0.25 11.1 32.6 0.59 9.8 0.2 6.0 1 1 5 7 7 7 0 Bacterial collagen, middle region CdvA PF18822.1 AAAP01003755.1_8 - 0.36 10.7 24.4 2.9 7.7 1.4 7.7 4 3 1 7 7 7 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 AAAP01003755.1_8 - 0.54 10.3 45.1 0.78 9.8 0.1 7.9 1 1 5 8 8 8 0 Protein of unknown function (DUF1664) Tn7_Tnp_TnsA_C PF08721.11 AAAP01003755.1_8 - 0.7 10.6 7.1 16 6.2 0.4 4.6 4 0 0 4 4 3 0 TnsA endonuclease C terminal DUF4381 PF14316.6 AAAP01003755.1_8 - 0.98 9.7 6.6 0.3 11.3 0.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4381) DUF948 PF06103.11 AAAP01003755.1_8 - 1.7 9.0 46.3 8.9 6.7 2.7 10.1 1 1 8 10 10 10 0 Bacterial protein of unknown function (DUF948) DUF2935 PF11155.8 AAAP01003755.1_8 - 3.1 8.1 21.8 6.1 7.2 0.1 6.8 5 3 0 5 5 5 0 Domain of unknown function (DUF2935) CorA PF01544.18 AAAP01003755.1_8 - 7.8 5.7 37.0 0.67 9.2 4.5 5.4 1 1 6 7 7 7 0 CorA-like Mg2+ transporter protein MYO10_CC PF16735.5 AAAP01003755.1_8 - 8.1 6.6 7.4 2.8 8.1 0.1 4.1 4 0 0 4 4 3 0 Unconventional myosin-X coiled coil domain Utp12 PF04003.12 AAAP01003755.1_8 - 9.9 6.5 11.5 13 6.2 0.1 5.5 5 2 1 7 7 7 0 Dip2/Utp12 Family UvrD-helicase PF00580.21 AAAP01003755.1_9 - 1e-48 166.5 0.0 4.5e-27 95.4 0.0 2.2 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AAAP01003755.1_9 - 1.2e-31 110.4 0.0 2.8e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAAP01003755.1_9 - 3e-26 92.5 0.0 5.6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAAP01003755.1_9 - 2e-13 49.9 0.0 2.2e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAAP01003755.1_9 - 1.1e-07 31.8 0.1 0.0052 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AAAP01003755.1_9 - 0.0024 17.7 0.0 0.43 10.3 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 AAAP01003755.1_9 - 0.066 12.8 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AAAP01003755.1_9 - 0.26 11.1 0.0 0.64 9.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain CheB_methylest PF01339.17 AAAP01003756.1_1 - 6.2e-56 188.8 0.0 1e-55 188.1 0.0 1.4 1 0 0 1 1 1 1 CheB methylesterase CheR PF01739.18 AAAP01003756.1_1 - 1.6e-54 184.4 0.0 2.5e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain PAS_10 PF13596.6 AAAP01003756.1_1 - 5e-27 94.6 0.0 1.6e-26 93.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain CheR_N PF03705.15 AAAP01003756.1_1 - 7.9e-15 54.3 0.1 2e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain PAS_4 PF08448.10 AAAP01003756.1_1 - 9.1e-06 25.9 0.4 0.61 10.4 0.0 3.7 3 0 0 3 3 3 1 PAS fold ATG16 PF08614.11 AAAP01003756.1_1 - 2.3e-05 24.7 5.3 4e-05 23.9 5.3 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PAS PF00989.25 AAAP01003756.1_1 - 0.00012 22.0 0.0 0.033 14.2 0.0 3.4 3 0 0 3 3 3 1 PAS fold AIP3 PF03915.13 AAAP01003756.1_1 - 0.00015 21.0 0.2 0.00027 20.2 0.2 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 CENP-F_leu_zip PF10473.9 AAAP01003756.1_1 - 0.00016 21.7 15.6 0.00032 20.7 15.6 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 AAAP01003756.1_1 - 0.00028 21.0 1.8 0.0006 19.9 1.8 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion PAS_9 PF13426.7 AAAP01003756.1_1 - 0.0009 19.5 0.0 0.33 11.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain Golgin_A5 PF09787.9 AAAP01003756.1_1 - 0.0027 17.2 12.5 0.0058 16.1 12.5 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 5 Med30 PF11315.8 AAAP01003756.1_1 - 0.0032 17.7 3.9 0.0041 17.3 2.6 1.7 2 0 0 2 2 1 1 Mediator complex subunit 30 Spc7 PF08317.11 AAAP01003756.1_1 - 0.0048 15.8 13.4 0.0079 15.1 13.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Leu_zip PF15294.6 AAAP01003756.1_1 - 0.005 16.4 8.0 0.008 15.7 8.0 1.2 1 0 0 1 1 1 1 Leucine zipper Snapin_Pallidin PF14712.6 AAAP01003756.1_1 - 0.0054 17.1 8.7 0.016 15.6 8.7 1.8 1 0 0 1 1 1 1 Snapin/Pallidin HMMR_N PF15905.5 AAAP01003756.1_1 - 0.0081 15.7 12.9 0.0083 15.6 10.8 1.8 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4795 PF16043.5 AAAP01003756.1_1 - 0.011 15.3 3.3 0.02 14.5 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 AAAP01003756.1_1 - 0.033 14.6 6.2 0.054 13.9 6.2 1.3 1 0 0 1 1 1 0 Fez1 Methyltransf_25 PF13649.6 AAAP01003756.1_1 - 0.035 14.8 0.0 2.6 8.8 0.0 3.3 1 1 0 1 1 1 0 Methyltransferase domain Laminin_II PF06009.12 AAAP01003756.1_1 - 0.047 13.7 6.1 0.093 12.8 6.1 1.5 1 0 0 1 1 1 0 Laminin Domain II Methyltransf_12 PF08242.12 AAAP01003756.1_1 - 0.049 14.4 0.0 0.29 11.9 0.0 2.4 2 1 0 2 2 1 0 Methyltransferase domain DUF812 PF05667.11 AAAP01003756.1_1 - 0.049 12.5 5.9 0.075 11.9 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) WEMBL PF05701.11 AAAP01003756.1_1 - 0.054 12.2 10.0 0.085 11.5 10.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Atg14 PF10186.9 AAAP01003756.1_1 - 0.061 12.4 2.8 0.096 11.8 2.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 AAAP01003756.1_1 - 0.065 12.6 11.6 0.12 11.7 11.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 AAAP01003756.1_1 - 0.067 12.8 2.9 0.11 12.0 2.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_gp64 PF03273.13 AAAP01003756.1_1 - 0.072 11.9 0.5 0.12 11.2 0.5 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family KASH_CCD PF14662.6 AAAP01003756.1_1 - 0.085 12.7 13.9 0.16 11.8 13.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 AAAP01003756.1_1 - 0.12 10.2 5.3 0.18 9.7 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.9 AAAP01003756.1_1 - 0.14 12.4 13.2 1.6 9.1 2.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein PilO PF04350.13 AAAP01003756.1_1 - 0.15 12.2 4.3 0.44 10.7 4.3 1.8 1 0 0 1 1 1 0 Pilus assembly protein, PilO Arfaptin PF06456.13 AAAP01003756.1_1 - 0.17 11.4 4.1 0.15 11.6 0.2 2.1 1 1 1 2 2 2 0 Arfaptin-like domain Seryl_tRNA_N PF02403.22 AAAP01003756.1_1 - 0.2 11.9 8.5 0.51 10.6 8.5 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3618 PF12277.8 AAAP01003756.1_1 - 0.25 11.6 1.5 1.1 9.6 1.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) HOOK PF05622.12 AAAP01003756.1_1 - 0.27 9.4 13.2 0.41 8.7 13.2 1.2 1 0 0 1 1 1 0 HOOK protein DUF3584 PF12128.8 AAAP01003756.1_1 - 0.31 8.5 8.8 0.46 7.9 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fusion_gly PF00523.18 AAAP01003756.1_1 - 0.34 9.1 3.0 0.66 8.2 3.0 1.5 1 0 0 1 1 1 0 Fusion glycoprotein F0 LXG PF04740.12 AAAP01003756.1_1 - 0.39 10.4 10.1 0.69 9.6 10.1 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily HIP1_clath_bdg PF16515.5 AAAP01003756.1_1 - 0.54 10.9 12.6 2 9.1 12.6 2.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 AAAP01003756.1_1 - 0.7 10.2 11.7 1.7 9.0 11.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 AAAP01003756.1_1 - 1 9.4 9.0 2.5 8.2 8.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 AAAP01003756.1_1 - 1 8.5 5.7 1.7 7.8 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 AAAP01003756.1_1 - 1.1 10.0 5.1 2.6 8.8 5.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) NRBF2 PF08961.10 AAAP01003756.1_1 - 1.3 8.6 7.1 2.5 7.7 7.1 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ADIP PF11559.8 AAAP01003756.1_1 - 1.3 9.1 13.7 2.4 8.2 13.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0449 PF15136.6 AAAP01003756.1_1 - 1.4 9.4 12.4 6.3 7.3 12.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DHR10 PF18595.1 AAAP01003756.1_1 - 1.5 8.9 15.6 15 5.7 0.1 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 AAAP01003756.1_1 - 1.5 7.3 6.6 2.3 6.7 6.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT57 PF10498.9 AAAP01003756.1_1 - 1.5 7.7 11.3 2.3 7.1 11.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 AAAP01003756.1_1 - 1.6 8.8 11.1 2.8 8.0 11.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 AAAP01003756.1_1 - 1.7 8.6 10.4 1.5 8.8 1.4 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cortex-I_coil PF09304.10 AAAP01003756.1_1 - 1.8 8.8 11.6 4.1 7.7 11.6 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil COG2 PF06148.11 AAAP01003756.1_1 - 1.9 8.6 6.9 5.7 7.0 6.9 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 AAAP01003756.1_1 - 2.1 7.6 5.2 3.5 6.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 AAAP01003756.1_1 - 2.2 8.2 5.2 5.8 6.9 5.2 1.7 1 0 0 1 1 1 0 Sec20 ZapB PF06005.12 AAAP01003756.1_1 - 2.3 8.7 21.4 1.9e+02 2.6 21.4 2.4 1 1 0 1 1 1 0 Cell division protein ZapB Fmp27_WPPW PF10359.9 AAAP01003756.1_1 - 2.4 6.9 6.6 3.7 6.3 6.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3552 PF12072.8 AAAP01003756.1_1 - 3.1 7.2 15.8 5.8 6.3 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 AAAP01003756.1_1 - 3.2 8.3 16.9 7.6 7.1 16.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF745 PF05335.13 AAAP01003756.1_1 - 3.9 7.2 11.7 7.2 6.3 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) HemX PF04375.14 AAAP01003756.1_1 - 3.9 6.7 10.3 6.2 6.0 10.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 AAAP01003756.1_1 - 5 7.0 14.3 3.6 7.4 5.4 2.5 1 1 1 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.11 AAAP01003756.1_1 - 7.8 7.1 10.5 32 5.1 10.4 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FliD_N PF02465.18 AAAP01003756.1_1 - 7.9 7.2 10.2 26 5.6 0.1 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3450 PF11932.8 AAAP01003756.1_1 - 9.1 5.5 15.9 2.6 7.3 12.6 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 AAAP01003756.1_1 - 9.6 6.4 8.6 16 5.7 8.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein HATPase_c PF02518.26 AAAP01003756.1_2 - 1.3e-19 70.8 0.0 1.4e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AAAP01003756.1_2 - 0.023 14.5 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01003756.1_2 - 0.052 13.4 0.0 0.07 13.0 0.0 1.3 1 1 0 1 1 1 0 GHKL domain HisKA PF00512.25 AAAP01003756.1_3 - 6.2e-09 35.8 0.7 2.3e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003756.1_3 - 0.00024 21.3 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain DUF4398 PF14346.6 AAAP01003756.1_3 - 0.0019 18.8 6.2 0.015 15.9 1.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4398) PAS PF00989.25 AAAP01003756.1_3 - 0.0089 16.0 0.0 0.026 14.5 0.0 1.8 1 1 1 2 2 2 1 PAS fold FlaF PF07309.11 AAAP01003756.1_4 - 0.082 12.9 0.2 0.17 11.9 0.2 1.7 1 1 0 1 1 1 0 Flagellar protein FlaF Auxin_canalis PF05703.11 AAAP01003756.1_4 - 0.34 10.8 1.7 0.56 10.1 1.7 1.3 1 0 0 1 1 1 0 Auxin canalisation Phage_holin_5_2 PF16079.5 AAAP01003756.1_5 - 0.025 14.9 0.1 0.026 14.8 0.1 1.0 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V OMP_b-brl_3 PF14905.6 AAAP01003756.1_6 - 0.095 11.7 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family Glycos_transf_2 PF00535.26 AAAP01003756.1_9 - 5.9e-19 68.5 0.0 1.9e-18 66.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003756.1_9 - 9e-18 65.0 0.0 1.4e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003756.1_9 - 0.00092 18.8 0.0 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PIG-P PF08510.12 AAAP01003756.1_9 - 0.16 11.9 1.1 0.29 11.1 1.1 1.3 1 0 0 1 1 1 0 PIG-P ABC_tran PF00005.27 AAAP01003756.1_10 - 1.5e-10 41.8 0.0 9.5e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003756.1_10 - 0.00013 21.9 0.1 0.035 13.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 AAAP01003756.1_10 - 0.065 12.6 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 AAAP01003756.1_10 - 0.092 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 AAAP01003756.1_10 - 0.1 12.9 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 AAAP01003756.1_11 - 2.4e-09 36.9 22.5 3.5e-09 36.4 22.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter DUF2079 PF09852.9 AAAP01003756.1_13 - 7.4e-37 127.3 17.5 9.9e-37 126.9 17.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) ABC2_membrane PF01061.24 AAAP01003756.1_14 - 0.0026 17.2 18.7 0.0026 17.2 18.7 1.5 2 0 0 2 2 2 1 ABC-2 type transporter Epimerase PF01370.21 AAAP01003756.1_15 - 7.5e-54 182.7 0.0 9.2e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003756.1_15 - 3.5e-49 168.0 0.0 4.6e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01003756.1_15 - 1.3e-13 50.8 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01003756.1_15 - 2.2e-12 46.6 0.0 4.7e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01003756.1_15 - 6.1e-09 35.4 0.0 1.1e-07 31.3 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003756.1_15 - 4.8e-05 22.7 0.0 0.017 14.3 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AAAP01003756.1_15 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAAP01003756.1_15 - 0.00074 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 AAAP01003756.1_15 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 AAAP01003756.1_15 - 0.035 14.0 0.8 0.27 11.1 0.8 2.3 1 1 0 1 1 1 0 KR domain ABC_tran PF00005.27 AAAP01003756.1_16 - 3.2e-17 63.3 0.1 3.6e-16 59.9 0.1 2.1 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01003756.1_16 - 1.1e-05 25.0 0.4 0.054 12.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAAP01003756.1_16 - 0.00059 19.7 0.3 0.0013 18.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 AAAP01003756.1_16 - 0.0011 19.0 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AAAP01003756.1_16 - 0.0082 16.1 0.2 0.032 14.2 0.0 2.0 3 0 0 3 3 3 1 NACHT domain MMR_HSR1 PF01926.23 AAAP01003756.1_16 - 0.012 15.6 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 AAAP01003756.1_16 - 0.013 15.9 0.0 0.051 14.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 AAAP01003756.1_16 - 0.015 12.9 0.0 0.021 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.6 AAAP01003756.1_16 - 0.019 15.5 0.0 0.029 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AAAP01003756.1_16 - 0.019 14.7 0.1 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003756.1_16 - 0.026 14.9 0.4 0.041 14.3 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AAAP01003756.1_16 - 0.038 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 AAAP01003756.1_16 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2813 PF11398.8 AAAP01003756.1_16 - 0.12 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_5 PF07728.14 AAAP01003756.1_16 - 0.19 11.7 0.2 0.64 10.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 AAAP01003756.1_16 - 0.2 11.3 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain HTH_18 PF12833.7 AAAP01003757.1_2 - 1.2e-20 73.6 0.3 2.4e-20 72.6 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003757.1_2 - 4e-06 26.8 0.0 0.034 14.3 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_11 PF08279.12 AAAP01003757.1_2 - 0.00062 19.7 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 AAAP01003757.1_2 - 0.051 13.2 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF1874 PF08960.10 AAAP01003757.1_2 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) HlyD_3 PF13437.6 AAAP01003757.1_4 - 7.2e-06 26.7 0.0 0.00039 21.1 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003757.1_4 - 0.0011 18.3 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003757.1_4 - 0.0052 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like Peptidase_M50 PF02163.22 AAAP01003757.1_4 - 0.0098 15.2 1.9 0.0098 15.2 1.9 2.8 1 1 1 2 2 2 1 Peptidase family M50 HlyD_3 PF13437.6 AAAP01003757.1_5 - 7.7e-20 71.6 0.5 3e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003757.1_5 - 3.9e-10 39.3 0.1 5.9e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003757.1_5 - 1.9e-09 37.2 0.0 6.2e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003757.1_5 - 0.0011 18.7 0.1 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme CodY PF06018.14 AAAP01003757.1_5 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 CodY GAF-like domain DUF1156 PF06634.12 AAAP01003757.1_5 - 0.082 13.0 0.5 0.23 11.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) HlyD_3 PF13437.6 AAAP01003757.1_6 - 1.1e-17 64.7 2.2 2e-16 60.6 0.6 2.4 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003757.1_6 - 1.1e-15 57.5 1.3 1.4e-15 57.1 1.3 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003757.1_6 - 1.2e-09 37.8 9.6 7.2e-06 25.7 0.4 3.8 4 0 0 4 4 4 2 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 AAAP01003757.1_6 - 0.00014 21.6 0.2 0.36 10.6 0.0 2.4 2 1 0 2 2 2 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl PF00364.22 AAAP01003757.1_6 - 0.00047 19.9 0.0 0.97 9.3 0.0 2.8 2 0 0 2 2 2 2 Biotin-requiring enzyme OEP PF02321.18 AAAP01003757.1_7 - 1.6e-25 90.0 22.1 4.2e-13 49.5 7.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein LcrG PF07216.12 AAAP01003757.1_7 - 0.0095 15.8 1.8 0.014 15.3 0.4 2.0 2 0 0 2 2 2 1 LcrG protein DraK_HK_N PF18092.1 AAAP01003757.1_7 - 0.06 13.8 0.9 5.2 7.6 0.4 2.6 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain Mito_fiss_reg PF05308.11 AAAP01003757.1_9 - 5.6 7.0 8.8 9.8 6.2 8.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_25 PF13481.6 AAAP01003758.1_2 - 1.3e-41 142.3 0.0 2.9e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain OAM_dimer PF16554.5 AAAP01003758.1_3 - 9.6 6.7 6.5 1.6 9.2 0.9 2.3 3 0 0 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase Fmp27_WPPW PF10359.9 AAAP01003758.1_4 - 0.019 13.8 1.8 0.024 13.5 1.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PIG-L PF02585.17 AAAP01003758.1_4 - 0.091 13.4 0.5 0.16 12.6 0.5 1.4 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase MAD PF05557.13 AAAP01003758.1_4 - 0.52 8.6 3.9 0.68 8.2 3.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Macoilin PF09726.9 AAAP01003758.1_4 - 2.1 6.8 4.8 2.6 6.5 4.8 1.1 1 0 0 1 1 1 0 Macoilin family TPR_MLP1_2 PF07926.12 AAAP01003758.1_4 - 4.9 7.2 11.6 2.6 8.1 8.5 2.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein LPD22 PF18834.1 AAAP01003758.1_9 - 1.6e-18 66.7 0.6 1.6e-18 66.7 0.6 4.4 4 0 0 4 4 4 1 Large polyvalent protein associated domain 22 PAPS_reduct PF01507.19 AAAP01003759.1_2 - 1.7e-35 122.6 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.19 AAAP01003759.1_3 - 1.6e-46 158.5 0.0 2.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family APS_kinase PF01583.20 AAAP01003759.1_4 - 2.3e-66 222.5 0.0 4.1e-66 221.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 AAAP01003759.1_4 - 7e-42 143.2 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAAP01003759.1_4 - 2.1e-08 34.2 0.0 1.7e-06 28.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AAAP01003759.1_4 - 2.5e-08 34.2 0.0 3.7e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAAP01003759.1_4 - 1.3e-06 29.0 0.0 0.0006 20.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003759.1_4 - 6.2e-06 26.7 0.1 0.0039 17.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU_D2 PF03144.25 AAAP01003759.1_4 - 1e-05 25.8 0.4 0.00024 21.4 0.2 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 AAAP01003759.1_4 - 1.9e-05 24.7 0.4 0.062 13.2 0.0 3.4 2 1 1 3 3 3 1 RsgA GTPase GTP_EFTU_D3 PF03143.17 AAAP01003759.1_4 - 3.3e-05 24.2 0.0 0.0001 22.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain AAA_29 PF13555.6 AAAP01003759.1_4 - 0.0004 20.1 0.1 0.13 12.1 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAAP01003759.1_4 - 0.00054 20.5 0.0 0.38 11.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MeaB PF03308.16 AAAP01003759.1_4 - 0.0019 17.2 0.7 0.0054 15.7 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 AAAP01003759.1_4 - 0.0035 16.6 0.1 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin CbiA PF01656.23 AAAP01003759.1_4 - 0.0036 17.4 0.0 0.0097 16.0 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 AAAP01003759.1_4 - 0.0064 16.3 0.1 0.83 9.4 0.0 3.0 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein MipZ PF09140.11 AAAP01003759.1_4 - 0.0066 15.8 0.1 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 ATPase MipZ GTP_EFTU_D4 PF14578.6 AAAP01003759.1_4 - 0.0089 15.9 0.8 0.024 14.5 0.2 2.1 2 0 0 2 2 1 1 Elongation factor Tu domain 4 SWI2_SNF2 PF18766.1 AAAP01003759.1_4 - 0.0093 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase NTPase_1 PF03266.15 AAAP01003759.1_4 - 0.014 15.3 0.4 0.91 9.4 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.19 AAAP01003759.1_4 - 0.017 14.7 0.7 7.6 6.1 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AAAP01003759.1_4 - 0.018 15.3 0.6 1.1 9.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain ParA PF10609.9 AAAP01003759.1_4 - 0.04 13.4 0.0 0.22 10.9 0.1 2.1 3 0 0 3 3 3 0 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 AAAP01003759.1_4 - 0.052 13.3 0.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01003759.1_4 - 0.055 13.1 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 AAAP01003759.1_4 - 0.06 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Roc PF08477.13 AAAP01003759.1_4 - 0.075 13.3 0.3 1.9 8.7 0.1 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 AAAP01003759.1_4 - 0.11 12.2 0.4 1.9 8.1 0.0 2.6 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 AAAP01003759.1_4 - 0.11 12.3 0.5 25 4.6 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 AAAP01003759.1_4 - 0.11 12.9 0.0 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 AAAP01003759.1_4 - 0.13 12.3 0.0 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 AAAP01003759.1_4 - 0.16 11.5 0.2 6.5 6.3 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B EAL PF00563.20 AAAP01003759.1_5 - 2.4e-50 171.3 0.0 2.9e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 EAL domain HSP20 PF00011.21 AAAP01003759.1_6 - 3.4e-18 65.7 0.0 4.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01003759.1_6 - 1.6e-05 24.4 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Methyltransf_25 PF13649.6 AAAP01003759.1_8 - 7.8e-05 23.3 0.2 0.00026 21.6 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 AAAP01003759.1_8 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MTS PF05175.14 AAAP01003759.1_8 - 0.00026 20.6 0.0 0.00052 19.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_30 PF05430.11 AAAP01003759.1_8 - 0.00031 20.6 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 AAAP01003759.1_8 - 0.017 15.7 0.1 0.044 14.4 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 AAAP01003759.1_8 - 0.15 13.1 0.0 0.43 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.28 AAAP01003759.1_9 - 4.6e-09 37.1 0.9 1.1e-07 32.6 0.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AAAP01003759.1_9 - 1.8e-06 28.2 0.0 3.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Redoxin PF08534.10 AAAP01003759.1_10 - 2.6e-14 53.2 0.0 3.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01003759.1_10 - 2.4e-12 46.8 0.0 3.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 AAAP01003759.1_10 - 4.2e-08 33.1 0.0 1.6e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 AAAP01003759.1_10 - 5.5e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAAP01003759.1_10 - 0.0018 18.7 0.0 0.0063 17.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 AAAP01003759.1_10 - 0.1 12.4 0.0 0.41 10.4 0.0 1.9 1 1 0 1 1 1 0 F plasmid transfer operon protein COX15-CtaA PF02628.15 AAAP01003759.1_11 - 1.8e-106 355.9 21.4 2e-106 355.7 21.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF155 PF02582.14 AAAP01003759.1_12 - 1e-23 84.3 0.0 1.4e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 dCache_1 PF02743.18 AAAP01003759.1_13 - 4e-12 46.5 0.0 5.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Cache domain Lactamase_B PF00753.27 AAAP01003760.1_1 - 4e-29 102.1 0.9 6e-29 101.5 0.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NMT1 PF09084.11 AAAP01003760.1_2 - 2.2e-28 99.7 0.0 3.7e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAAP01003760.1_2 - 1.1e-11 44.9 0.2 9e-11 41.9 0.2 2.2 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01003760.1_2 - 3.5e-10 39.9 0.2 5.5e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAAP01003760.1_2 - 8.5e-08 31.9 0.3 1.5e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 AAAP01003760.1_2 - 2.6e-05 23.8 0.0 6.5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NMT1-like family YhfZ_C PF14503.6 AAAP01003760.1_2 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 YhfZ C-terminal domain BPD_transp_1 PF00528.22 AAAP01003760.1_3 - 7.9e-18 64.8 14.5 1.3e-17 64.1 14.5 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01003760.1_4 - 4.7e-37 127.6 0.0 6.6e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003760.1_4 - 1.8e-05 24.7 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01003760.1_4 - 0.0032 17.4 0.2 0.0053 16.7 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 AAAP01003760.1_4 - 0.0037 16.1 0.5 0.79 8.4 0.2 2.5 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 AAAP01003760.1_4 - 0.0057 17.1 0.2 0.0095 16.3 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003760.1_4 - 0.0071 16.6 0.1 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003760.1_4 - 0.0087 15.8 0.4 0.017 14.8 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AAAP01003760.1_4 - 0.0098 15.8 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 AAAP01003760.1_4 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 AAAP01003760.1_4 - 0.028 14.7 0.3 0.069 13.4 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01003760.1_4 - 0.063 13.8 0.5 0.087 13.3 0.5 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003760.1_4 - 0.11 12.6 0.1 0.31 11.1 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01003760.1_4 - 0.16 11.4 0.0 13 5.1 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 AAAP01003760.1_4 - 0.17 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AAAP01003760.1_4 - 0.19 10.8 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AMP-binding PF00501.28 AAAP01003760.1_5 - 8.2e-94 314.6 0.0 1e-93 314.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003760.1_5 - 2.7e-24 85.9 0.6 9.9e-23 80.9 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAAP01003760.1_5 - 3.6e-19 68.4 2.3 4e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus OsmC PF02566.19 AAAP01003760.1_6 - 1.7e-07 31.6 0.1 3.7e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 OsmC-like protein Cys_Met_Meta_PP PF01053.20 AAAP01003760.1_7 - 1.6e-95 319.9 0.0 1.9e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAAP01003760.1_7 - 2e-07 30.3 0.0 3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01003760.1_8 - 5.4e-134 446.5 0.0 6.4e-134 446.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.6 AAAP01003760.1_8 - 2.2e-38 131.3 0.7 3.1e-37 127.6 0.1 2.7 3 0 0 3 3 3 1 CoA binding domain DegT_DnrJ_EryC1 PF01041.17 AAAP01003760.1_8 - 4.1e-07 29.6 0.0 8.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAAP01003760.1_8 - 9.3e-07 28.1 0.0 2.1e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01003760.1_8 - 1.6e-05 24.4 0.0 6.5e-05 22.3 0.0 2.0 2 1 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAAP01003760.1_8 - 1.8e-05 24.1 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CoA_binding PF02629.19 AAAP01003760.1_8 - 0.0016 19.1 0.0 0.0045 17.6 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain GDC-P PF02347.16 AAAP01003760.1_8 - 0.029 13.2 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein HTH_Crp_2 PF13545.6 AAAP01003760.1_9 - 6.7e-10 38.8 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003760.1_9 - 8.5e-09 35.4 0.1 1.8e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1465 PF07323.12 AAAP01003761.1_1 - 4.8e-22 78.5 0.9 5.1e-22 78.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) DUF4044 PF13253.6 AAAP01003761.1_1 - 0.02 14.4 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) MMtag PF10159.9 AAAP01003761.1_2 - 0.0067 16.7 0.0 0.0073 16.6 0.0 1.2 1 0 0 1 1 1 1 Multiple myeloma tumor-associated PBP_like_2 PF12849.7 AAAP01003761.1_3 - 1.7e-19 70.6 0.0 3.5e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAAP01003761.1_3 - 1.3e-10 41.5 0.5 4.1e-10 39.8 0.5 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAAP01003761.1_3 - 3e-05 23.2 0.0 5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PBP superfamily domain LysR_substrate PF03466.20 AAAP01003761.1_3 - 0.0094 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain PBP_like_2 PF12849.7 AAAP01003761.1_4 - 2.3e-22 80.0 0.0 2.6e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAAP01003761.1_4 - 6.6e-09 35.8 0.3 1.3e-08 34.9 0.3 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AAAP01003761.1_4 - 0.0094 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain ABC_tran PF00005.27 AAAP01003761.1_5 - 3.5e-27 95.6 0.0 5.5e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003761.1_5 - 4.9e-13 49.6 0.4 5.8e-08 32.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003761.1_5 - 0.0011 18.5 0.0 0.67 9.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003761.1_5 - 0.033 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003761.1_5 - 0.034 14.6 0.0 0.048 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003761.1_5 - 0.051 13.1 0.5 0.1 12.1 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAAP01003761.1_5 - 0.055 13.2 0.0 8.3 6.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 AAAP01003761.1_5 - 0.094 13.0 0.1 1.3 9.3 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Radical_SAM PF04055.21 AAAP01003761.1_7 - 1e-28 100.8 0.0 5.2e-27 95.3 0.0 2.7 3 1 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 AAAP01003761.1_7 - 1.8e-19 69.6 0.0 3.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM_2 PF18693.1 AAAP01003761.1_7 - 5.6e-19 68.1 3.3 1.3e-18 66.9 3.3 1.6 1 0 0 1 1 1 1 TRAM domain TRAM PF01938.20 AAAP01003761.1_7 - 0.0071 16.3 0.3 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 TRAM domain RNase_II_C_S1 PF18614.1 AAAP01003761.1_7 - 0.088 12.8 1.9 2 8.4 0.1 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain CLP1_P PF16575.5 AAAP01003761.1_7 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HATPase_c PF02518.26 AAAP01003761.1_8 - 7.5e-27 94.1 0.0 1.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003761.1_8 - 8.8e-20 70.5 0.3 2.9e-19 68.9 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003761.1_8 - 1.5e-12 47.8 0.0 8.7e-11 42.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01003761.1_8 - 5.5e-09 36.2 0.0 2.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003761.1_8 - 0.00011 22.2 0.0 0.00033 20.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AAAP01003761.1_8 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain AAA_31 PF13614.6 AAAP01003761.1_9 - 3.1e-42 144.5 0.0 4.3e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01003761.1_9 - 8.1e-19 67.9 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAAP01003761.1_9 - 3.3e-13 49.7 0.9 5.5e-12 45.7 0.9 2.1 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAAP01003761.1_9 - 6e-13 48.7 0.6 1.4e-08 34.4 0.2 2.1 2 0 0 2 2 2 2 ATPase MipZ Fer4_NifH PF00142.18 AAAP01003761.1_9 - 4.3e-08 32.9 0.0 2.4e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AAAP01003761.1_9 - 6.4e-08 32.4 0.5 1.9e-06 27.6 0.5 2.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAAP01003761.1_9 - 1.2e-06 28.0 1.7 1.2e-06 27.9 0.2 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase SRP54 PF00448.22 AAAP01003761.1_9 - 0.02 14.6 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain VirC1 PF07015.11 AAAP01003761.1_9 - 0.026 13.8 0.3 0.067 12.5 0.1 1.6 2 0 0 2 2 2 0 VirC1 protein AAA_25 PF13481.6 AAAP01003761.1_9 - 0.04 13.5 1.5 1.2 8.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 AAAP01003761.1_9 - 0.051 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Usp PF00582.26 AAAP01003761.1_9 - 0.096 13.2 2.4 0.41 11.2 0.2 2.2 2 0 0 2 2 2 0 Universal stress protein family CLP1_P PF16575.5 AAAP01003761.1_9 - 0.19 11.5 0.1 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HTH_27 PF13463.6 AAAP01003761.1_10 - 2.7e-14 53.4 0.1 1e-13 51.5 0.0 2.0 1 1 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AAAP01003761.1_10 - 1.7e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AAAP01003761.1_10 - 0.00068 19.8 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AAAP01003761.1_10 - 0.0024 17.8 0.0 0.0071 16.3 0.0 1.9 2 0 0 2 2 2 1 MarR family Lyase_1 PF00206.20 AAAP01003761.1_11 - 2.6e-53 181.4 0.0 4e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 AAAP01003761.1_11 - 5.5e-24 84.5 0.1 1.5e-23 83.1 0.1 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 AAAP01003761.1_11 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal DDE_5 PF13546.6 AAAP01003762.1_1 - 4.1e-07 29.6 0.0 4.7e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 AAAP01003762.1_2 - 2.1e-13 49.6 2.2 1.5e-09 37.3 0.3 2.7 3 0 0 3 3 3 2 Homeodomain-like domain DDE_3 PF13358.6 AAAP01003762.1_2 - 2.1e-12 47.0 0.0 3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 AAAP01003762.1_2 - 1.1e-10 41.3 0.9 9e-08 32.0 0.1 2.5 2 0 0 2 2 2 2 Winged helix-turn helix HTH_32 PF13565.6 AAAP01003762.1_2 - 8e-10 39.2 0.5 8e-10 39.2 0.5 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 AAAP01003762.1_2 - 9.2e-10 38.5 5.7 6.7e-09 35.7 1.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 AAAP01003762.1_2 - 6.5e-07 29.8 1.0 5.1e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 AAAP01003762.1_2 - 0.00011 21.5 5.1 0.00059 19.2 0.3 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 AAAP01003762.1_2 - 0.0036 17.1 0.5 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain P22_Cro PF14549.6 AAAP01003762.1_2 - 0.005 16.7 1.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 2 DNA-binding transcriptional regulator Cro YdaS_antitoxin PF15943.5 AAAP01003762.1_2 - 0.0093 15.8 0.5 0.84 9.5 0.0 3.2 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_1 PF01527.20 AAAP01003762.1_2 - 0.015 15.6 0.7 0.05 13.9 0.2 2.0 2 0 0 2 2 2 0 Transposase HTH_24 PF13412.6 AAAP01003762.1_2 - 0.015 14.9 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 AAAP01003762.1_2 - 0.056 13.1 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_1_2 PF13022.6 AAAP01003762.1_2 - 0.072 13.2 0.0 0.99 9.6 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase Terminase_5 PF06056.12 AAAP01003762.1_2 - 0.074 13.0 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_1 PF00126.27 AAAP01003762.1_2 - 0.13 12.2 0.2 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_1 PF01527.20 AAAP01003762.1_3 - 4.1e-15 55.9 1.8 4.8e-15 55.6 1.8 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01003762.1_3 - 1.2e-05 24.9 1.0 1.4e-05 24.7 0.1 1.7 2 0 0 2 2 2 1 Homeodomain-like domain bZIP_2 PF07716.15 AAAP01003762.1_3 - 0.004 17.2 0.5 0.0086 16.1 0.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper HTH_Tnp_IS630 PF01710.16 AAAP01003762.1_3 - 0.0072 16.4 0.4 0.0088 16.1 0.4 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_1_2 PF13022.6 AAAP01003762.1_3 - 0.014 15.5 0.1 0.018 15.2 0.1 1.3 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 AAAP01003762.1_3 - 0.016 15.3 0.4 0.033 14.2 0.4 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003762.1_3 - 0.028 14.5 0.2 0.075 13.2 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 AAAP01003762.1_3 - 0.038 14.1 0.1 0.096 12.8 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_7 PF02796.15 AAAP01003762.1_3 - 0.059 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DivIC PF04977.15 AAAP01003762.1_3 - 0.23 11.3 4.5 0.16 11.8 3.1 1.5 1 1 0 1 1 1 0 Septum formation initiator Pentapeptide PF00805.22 AAAP01003762.1_4 - 1.6e-45 152.2 63.7 1.2e-10 40.8 3.8 5.7 1 1 5 7 7 7 7 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAAP01003762.1_4 - 2.6e-19 69.1 0.0 6.9e-07 29.4 0.0 2.9 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AAAP01003762.1_4 - 9.6e-18 64.1 0.1 1.6e-06 28.2 0.5 4.0 2 2 1 4 4 4 3 Pentapeptide repeats (9 copies) DivIC PF04977.15 AAAP01003762.1_5 - 0.0035 17.1 0.3 0.0036 17.0 0.3 1.1 1 0 0 1 1 1 1 Septum formation initiator Dynamitin PF04912.14 AAAP01003762.1_5 - 0.009 15.4 0.1 0.009 15.4 0.1 1.1 1 0 0 1 1 1 1 Dynamitin ABC_tran_CTD PF16326.5 AAAP01003762.1_5 - 0.026 14.8 2.1 0.034 14.4 2.1 1.5 1 1 0 1 1 1 0 ABC transporter C-terminal domain GreA_GreB_N PF03449.15 AAAP01003762.1_5 - 0.029 14.5 1.3 0.049 13.8 0.6 1.7 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal MerR-DNA-bind PF09278.11 AAAP01003762.1_5 - 0.038 14.5 1.8 0.061 13.9 1.8 1.4 1 0 0 1 1 1 0 MerR, DNA binding DUF4230 PF14014.6 AAAP01003762.1_6 - 0.17 12.1 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Trypsin_2 PF13365.6 AAAP01003762.1_8 - 4.9e-29 102.2 2.3 1e-28 101.1 2.3 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain MCR PF18509.1 AAAP01003762.1_8 - 2.1e-28 97.5 17.7 5e-14 51.6 5.9 2.6 2 0 0 2 2 2 2 Magnetochrome domain Trypsin PF00089.26 AAAP01003762.1_8 - 1.1e-13 51.6 0.1 1.7e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 AAAP01003762.1_8 - 3.7e-10 39.5 0.2 8.6e-10 38.3 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AAAP01003762.1_8 - 5.2e-10 39.5 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AAAP01003762.1_8 - 3.6e-08 33.6 0.0 1.2e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 PDZ domain Peptidase_S55 PF05580.12 AAAP01003762.1_8 - 0.0041 17.1 0.9 0.013 15.4 0.8 1.8 2 0 0 2 2 2 1 SpoIVB peptidase S55 PDZ_1 PF12812.7 AAAP01003762.1_8 - 0.019 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain Peptidase_S29 PF02907.15 AAAP01003762.1_8 - 0.02 14.6 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Cytochrome_CBB3 PF13442.6 AAAP01003762.1_8 - 0.031 14.6 2.3 1.9 8.9 0.4 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Peptidase_S46 PF10459.9 AAAP01003762.1_8 - 0.057 12.1 1.6 2.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 Cytochrome_C7 PF14522.6 AAAP01003762.1_8 - 0.6 10.1 2.5 3.3 7.8 2.6 1.9 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C PF00034.21 AAAP01003762.1_8 - 0.72 11.0 9.9 3.1 9.0 3.3 2.4 1 1 1 2 2 2 0 Cytochrome c Cytochrom_c3_2 PF14537.6 AAAP01003762.1_8 - 2 9.0 5.2 12 6.4 5.3 1.9 1 1 0 1 1 1 0 Cytochrome c3 PSCyt3 PF07627.11 AAAP01003762.1_8 - 2.1 8.7 6.1 5.2 7.4 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) SPESP1 PF15754.5 AAAP01003762.1_9 - 0.06 12.5 9.6 0.099 11.8 9.6 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Trypsin_2 PF13365.6 AAAP01003762.1_10 - 2.6e-16 60.9 0.9 3.9e-16 60.3 0.9 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAAP01003762.1_10 - 0.012 15.4 0.8 0.19 11.5 0.8 2.1 1 1 0 1 1 1 0 Trypsin NAC PF01849.18 AAAP01003762.1_10 - 0.14 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 NAC domain LemA PF04011.12 AAAP01003762.1_11 - 2.9e-25 88.9 0.0 5.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 LemA family LptF_LptG PF03739.14 AAAP01003763.1_1 - 5.9e-44 150.3 0.4 7.2e-44 150.1 0.4 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF2975 PF11188.8 AAAP01003763.1_1 - 0.15 11.9 4.5 0.31 10.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) PAP2 PF01569.21 AAAP01003763.1_2 - 7e-21 74.4 0.2 7e-21 74.4 0.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AAAP01003763.1_2 - 6.3e-08 32.5 2.5 6.3e-08 32.5 2.5 1.6 2 1 0 2 2 2 1 PAP2 superfamily 5TM-5TMR_LYT PF07694.12 AAAP01003763.1_2 - 0.048 13.2 4.7 0.16 11.5 1.8 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT CSD PF00313.22 AAAP01003763.1_3 - 4.4e-37 125.8 0.5 5.4e-20 71.0 0.3 2.1 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01003763.1_3 - 2e-10 40.2 0.5 4.8e-05 23.0 0.2 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Epimerase PF01370.21 AAAP01003763.1_5 - 0.00015 21.3 0.0 0.13 11.7 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 AAAP01003763.1_5 - 0.014 15.6 0.0 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_6 PF13480.7 AAAP01003763.1_5 - 0.046 13.9 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_2 PF07719.17 AAAP01003763.1_6 - 3.1e-14 51.8 7.4 0.0016 18.4 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003763.1_6 - 5.3e-09 36.1 18.4 0.00023 21.2 0.1 4.7 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003763.1_6 - 8.2e-09 34.9 6.0 0.00081 19.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003763.1_6 - 1.9e-06 28.4 16.6 0.005 17.5 5.4 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003763.1_6 - 5.1e-05 22.9 4.6 0.0077 15.9 0.0 4.0 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 AAAP01003763.1_6 - 0.00014 22.3 9.6 0.0043 17.5 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003763.1_6 - 0.003 17.7 0.3 0.42 10.9 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AAAP01003763.1_6 - 0.0037 17.4 4.9 0.36 11.2 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003763.1_6 - 0.0041 17.4 12.1 0.44 10.9 3.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003763.1_6 - 0.0057 17.0 4.1 10 6.8 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat FhuF PF06276.12 AAAP01003763.1_6 - 0.056 13.9 0.3 0.086 13.2 0.3 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Fis1_TPR_C PF14853.6 AAAP01003763.1_6 - 0.1 12.7 0.6 17 5.6 0.1 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003763.1_6 - 1.1 10.0 11.0 13 6.6 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003763.1_6 - 2.2 9.3 23.4 1.6 9.7 0.9 5.4 2 1 4 6 6 5 0 Tetratricopeptide repeat BolA PF01722.18 AAAP01003763.1_7 - 7.4e-31 106.3 0.1 8.7e-31 106.0 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein DnaJ PF00226.31 AAAP01003763.1_8 - 2.7e-15 56.2 0.2 6.6e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain CobS_N PF12556.8 AAAP01003763.1_9 - 7.8e-17 60.7 0.2 1.5e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 Cobaltochelatase CobS subunit N terminal AAA_5 PF07728.14 AAAP01003763.1_9 - 6.5e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01003763.1_9 - 0.0003 21.2 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AAAP01003763.1_9 - 0.0022 18.1 0.0 0.0035 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AAAP01003763.1_9 - 0.0042 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbbQ_C PF08406.10 AAAP01003763.1_9 - 0.01 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_18 PF13238.6 AAAP01003763.1_9 - 0.023 15.3 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003763.1_9 - 0.027 14.9 0.0 0.099 13.0 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 AAAP01003763.1_9 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAAP01003763.1_9 - 0.18 12.0 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CobT_C PF11775.8 AAAP01003763.1_10 - 4.6e-103 343.5 0.1 7.8e-103 342.8 0.1 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain CobT PF06213.12 AAAP01003763.1_10 - 3e-78 263.0 8.2 5.3e-78 262.2 8.2 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA_2 PF13519.6 AAAP01003763.1_10 - 0.0097 16.5 0.0 1.6 9.4 0.0 3.3 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 AAAP01003763.1_10 - 0.043 14.1 0.0 0.5 10.6 0.0 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Roughex PF06020.11 AAAP01003763.1_10 - 0.83 8.7 5.7 1.3 8.0 5.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein HisKA_2 PF07568.12 AAAP01003763.1_11 - 1.7e-25 88.9 0.4 3.2e-25 88.0 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 AAAP01003763.1_11 - 5.8e-08 33.2 0.1 7.1e-07 29.7 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 AAAP01003763.1_11 - 4.4e-07 30.5 0.1 1.2e-06 29.1 0.1 1.8 1 0 0 1 1 1 1 HWE histidine kinase dCache_1 PF02743.18 AAAP01003763.1_11 - 1.9e-06 27.9 0.0 3.9e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Cache domain HATPase_c_2 PF13581.6 AAAP01003763.1_11 - 5e-05 23.3 0.0 0.00022 21.2 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain PGAP1 PF07819.13 AAAP01003763.1_11 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein SPOB_a PF14689.6 AAAP01003763.1_11 - 0.13 12.0 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain MoCF_biosynth PF00994.24 AAAP01003763.1_12 - 4.5e-30 104.2 0.0 5.5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain YbjQ_1 PF01906.17 AAAP01003763.1_13 - 1.5e-37 128.4 2.5 1.6e-37 128.3 2.5 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding PSCyt1 PF07635.11 AAAP01003763.1_14 - 1.8e-09 38.1 0.0 2.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Planctomycete cytochrome C Cytochrome_CBB3 PF13442.6 AAAP01003763.1_14 - 0.083 13.2 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Haem_bd PF14376.6 AAAP01003763.1_14 - 0.13 12.3 0.0 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain Extensin-like_C PF06904.12 AAAP01003763.1_15 - 5.8e-56 189.3 1.2 6.8e-56 189.1 1.2 1.0 1 0 0 1 1 1 1 Extensin-like protein C-terminus Izumo-Ig PF16706.5 AAAP01003763.1_15 - 0.038 14.1 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain HTH_Tnp_1 PF01527.20 AAAP01003764.1_1 - 7.2e-18 64.7 0.0 7.8e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01003764.1_1 - 0.00052 19.7 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003764.1_1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003764.1_1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAAP01003764.1_1 - 0.042 14.0 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Dyp_perox PF04261.12 AAAP01003764.1_2 - 1.3e-72 244.6 0.0 1.7e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family GreA_GreB_N PF03449.15 AAAP01003764.1_3 - 2e-31 107.9 1.6 2.7e-31 107.5 1.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AAAP01003764.1_3 - 1.8e-30 104.6 0.1 2.7e-30 104.1 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term WD40_alt PF14077.6 AAAP01003764.1_3 - 0.057 13.3 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif PapC_C PF13953.6 AAAP01003764.1_3 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PapC C-terminal domain CPSase_L_D2 PF02786.17 AAAP01003764.1_4 - 5.4e-106 352.8 0.3 6.4e-66 221.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AAAP01003764.1_4 - 4.1e-36 124.0 0.0 8.2e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AAAP01003764.1_4 - 1.2e-20 73.5 0.3 6.3e-20 71.2 0.1 2.5 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.22 AAAP01003764.1_4 - 3.8e-14 52.6 0.0 8.9e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 AAAP01003764.1_4 - 6.5e-11 42.1 0.1 3.5e-06 26.8 0.1 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 AAAP01003764.1_4 - 9.2e-11 42.0 0.1 2.9e-07 30.7 0.0 3.5 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAAP01003764.1_4 - 1e-07 31.7 0.1 0.00035 20.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.11 AAAP01003764.1_4 - 4.7e-06 26.3 0.0 0.0054 16.3 0.0 3.6 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 AAAP01003764.1_4 - 0.0003 20.3 0.0 0.0038 16.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 AAAP01003764.1_4 - 0.015 14.9 0.5 3.5 7.1 0.0 3.2 3 1 0 3 3 3 0 ATP-grasp domain TSR PF18487.1 AAAP01003764.1_4 - 0.13 12.5 0.4 0.32 11.2 0.4 1.6 1 0 0 1 1 1 0 Thrombospondin type 1 repeat CPSase_sm_chain PF00988.22 AAAP01003764.1_5 - 6.1e-49 165.1 0.0 9.7e-49 164.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AAAP01003764.1_5 - 2.2e-47 161.3 0.0 2.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01003764.1_5 - 3.7e-11 43.2 0.4 3.5e-05 23.6 0.1 2.3 1 1 1 2 2 2 2 Peptidase C26 GATase_3 PF07685.14 AAAP01003764.1_5 - 0.043 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain YqeY PF09424.10 AAAP01003764.1_6 - 1.8e-45 154.5 4.0 2e-45 154.4 4.0 1.0 1 0 0 1 1 1 1 Yqey-like protein Toprim_N PF08275.11 AAAP01003764.1_7 - 4.8e-42 143.0 0.0 7.6e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AAAP01003764.1_7 - 5.7e-36 122.3 0.0 9.8e-36 121.5 0.0 1.4 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_4 PF13662.6 AAAP01003764.1_7 - 2.1e-16 60.2 0.0 3.8e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAAP01003764.1_7 - 3.8e-12 46.5 0.0 7.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AAAP01003764.1_7 - 2.5e-05 24.4 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 AAAP01003764.1_7 - 0.058 13.8 0.1 0.14 12.6 0.0 1.6 2 0 0 2 2 2 0 Toprim domain Virulence_RhuM PF13310.6 AAAP01003764.1_8 - 0.017 14.4 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Virulence protein RhuM family DnaG_DnaB_bind PF08278.11 AAAP01003764.1_8 - 0.027 15.1 0.3 0.066 13.8 0.0 1.7 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding DnaB_bind PF10410.9 AAAP01003764.1_8 - 0.26 11.5 2.2 1.2 9.4 0.4 2.4 2 1 0 2 2 2 0 DnaB-helicase binding domain of primase Sigma70_r1_1 PF03979.14 AAAP01003764.1_9 - 2.6e-23 81.9 1.5 2.6e-23 81.9 1.5 2.4 2 1 0 2 2 2 1 Sigma-70 factor, region 1.1 Sigma70_ner PF04546.13 AAAP01003764.1_9 - 6.2e-15 55.6 0.1 6.2e-15 55.6 0.1 2.6 2 1 0 2 2 2 1 Sigma-70, non-essential region Sigma70_r1_2 PF00140.20 AAAP01003764.1_9 - 2.1e-14 53.2 0.4 5.2e-14 52.0 0.4 1.7 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 EFhand_Ca_insen PF08726.10 AAAP01003764.1_9 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Ub-RnfH PF03658.14 AAAP01003765.1_1 - 8.9e-36 122.1 0.0 1e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin Ub-Mut7C PF14451.6 AAAP01003765.1_1 - 0.0048 16.7 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Mut7-C ubiquitin SLBB PF10531.9 AAAP01003765.1_1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 SLBB domain EppA_BapA PF07268.11 AAAP01003765.1_1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Rnf-Nqr PF02508.14 AAAP01003765.1_2 - 3.8e-46 157.2 8.8 1.5e-45 155.3 8.8 1.8 1 1 0 1 1 1 1 Rnf-Nqr subunit, membrane protein FMN_bind PF04205.14 AAAP01003765.1_3 - 1.7e-20 73.3 0.0 3.1e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 FMN-binding domain NQR2_RnfD_RnfE PF03116.15 AAAP01003765.1_4 - 8.6e-105 350.3 15.8 9.8e-105 350.1 15.8 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family Complex1_51K PF01512.17 AAAP01003765.1_5 - 1.7e-48 164.3 0.6 3.3e-48 163.4 0.6 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit RnfC_N PF13375.6 AAAP01003765.1_5 - 3e-34 117.0 0.1 1.7e-33 114.6 0.0 2.3 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain SLBB PF10531.9 AAAP01003765.1_5 - 1.2e-14 53.9 0.8 2.5e-14 52.9 0.8 1.6 1 0 0 1 1 1 1 SLBB domain Fer4_10 PF13237.6 AAAP01003765.1_5 - 2e-06 27.8 11.1 8.2e-06 25.8 11.5 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003765.1_5 - 4.5e-06 27.2 9.0 1.3e-05 25.7 9.1 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003765.1_5 - 7.1e-06 26.1 9.3 2.6e-05 24.3 9.5 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003765.1_5 - 7.3e-06 26.4 11.7 0.0033 17.9 0.3 3.1 4 0 0 4 4 2 2 4Fe-4S dicluster domain NQRA PF05896.11 AAAP01003765.1_5 - 9.1e-06 25.3 0.1 0.00014 21.4 0.0 2.3 3 0 0 3 3 3 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Fer4_8 PF13183.6 AAAP01003765.1_5 - 1.5e-05 25.4 20.3 0.00021 21.7 11.3 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain NQRA_SLBB PF11973.8 AAAP01003765.1_5 - 4.7e-05 23.9 0.2 0.00012 22.6 0.2 1.7 1 0 0 1 1 1 1 NQRA C-terminal domain Fer4_4 PF12800.7 AAAP01003765.1_5 - 6.9e-05 23.0 12.8 0.038 14.5 4.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003765.1_5 - 7.7e-05 22.6 14.7 0.032 14.3 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003765.1_5 - 0.00016 21.9 11.6 0.016 15.4 0.5 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003765.1_5 - 0.00024 20.8 18.0 0.043 13.6 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003765.1_5 - 0.0014 18.7 11.4 0.0088 16.2 12.0 2.1 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAAP01003765.1_5 - 0.0082 15.9 3.2 0.021 14.6 3.2 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_16 PF13484.6 AAAP01003765.1_5 - 0.011 16.6 11.0 0.74 10.8 1.2 3.0 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AAAP01003765.1_5 - 0.017 15.2 16.8 0.18 11.9 5.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Biotin_lipoyl PF00364.22 AAAP01003765.1_5 - 0.017 14.9 0.1 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 Biotin-requiring enzyme Striatin PF08232.12 AAAP01003765.1_5 - 1.1 9.9 5.9 1.8 9.2 5.9 1.3 1 0 0 1 1 1 0 Striatin family Fer4_22 PF17179.4 AAAP01003765.1_5 - 1.1 10.2 16.6 0.3 11.9 1.1 2.6 1 1 3 4 4 4 0 4Fe-4S dicluster domain zf-CSL PF05207.13 AAAP01003765.1_5 - 2 8.2 6.9 88 2.9 6.9 2.4 1 1 0 1 1 1 0 CSL zinc finger Fer4_3 PF12798.7 AAAP01003765.1_5 - 5.5 8.2 20.7 3 9.0 3.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Biotin_lipoyl_2 PF13533.6 AAAP01003765.1_5 - 8.2 6.3 10.2 0.37 10.7 0.2 3.1 3 0 0 3 3 2 0 Biotin-lipoyl like Fer4_21 PF14697.6 AAAP01003765.1_6 - 5.5e-12 45.6 10.4 5.5e-12 45.6 10.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 AAAP01003765.1_6 - 3.6e-11 42.5 5.9 3.6e-11 42.5 5.9 2.6 3 0 0 3 3 2 1 Putative Fe-S cluster Fer4 PF00037.27 AAAP01003765.1_6 - 9.5e-11 41.0 21.1 1.9e-06 27.4 3.6 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003765.1_6 - 4.1e-08 32.9 21.0 3.6e-05 23.7 3.9 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003765.1_6 - 2.6e-06 27.5 10.3 2.6e-06 27.5 10.3 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003765.1_6 - 7.8e-06 26.7 12.9 0.00012 23.0 1.4 3.0 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01003765.1_6 - 5.6e-05 23.6 21.3 0.00057 20.4 10.7 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003765.1_6 - 9.4e-05 22.5 23.7 0.0033 17.5 3.0 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003765.1_6 - 0.032 14.3 21.8 0.032 14.3 2.3 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAAP01003765.1_6 - 0.71 10.8 14.5 0.7 10.8 0.6 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAAP01003765.1_6 - 1.7 9.4 11.8 0.36 11.6 1.1 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AAAP01003765.1_6 - 2.5 8.3 9.9 0.86 9.8 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003765.1_6 - 3.3 8.3 18.7 0.73 10.4 2.2 3.0 1 1 4 5 5 5 0 4Fe-4S dicluster domain Rnf-Nqr PF02508.14 AAAP01003765.1_7 - 1e-53 181.9 18.3 1.1e-53 181.7 18.3 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein SHS2_Rpb7-N PF03876.17 AAAP01003765.1_7 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RseC_MucC PF04246.12 AAAP01003765.1_8 - 3.1e-27 95.1 0.0 3.6e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC Gly-zipper_YMGG PF13441.6 AAAP01003765.1_8 - 3.1 7.6 8.0 8 6.3 8.0 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper ApbE PF02424.15 AAAP01003765.1_9 - 6.1e-61 206.2 0.1 7.6e-61 205.9 0.1 1.1 1 0 0 1 1 1 1 ApbE family Glyco_transf_41 PF13844.6 AAAP01003765.1_10 - 2.2e-45 155.0 0.0 3.1e-28 98.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 AAAP01003765.1_10 - 1.4e-30 102.9 19.5 6.5e-06 25.9 0.7 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003765.1_10 - 3.9e-29 99.2 7.8 1.4e-07 31.0 0.2 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003765.1_10 - 1.3e-26 90.5 2.1 1.2e-05 25.1 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003765.1_10 - 3.4e-22 78.8 33.5 1.4e-07 32.0 6.7 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003765.1_10 - 5.3e-21 74.0 6.3 3.5e-07 29.8 0.1 5.9 3 2 2 5 5 5 4 TPR repeat TPR_12 PF13424.6 AAAP01003765.1_10 - 1e-17 64.2 30.3 2.2e-08 34.2 1.2 5.7 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003765.1_10 - 4.7e-17 61.1 9.3 0.021 15.2 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003765.1_10 - 2e-15 57.1 21.8 0.0004 20.8 5.5 5.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003765.1_10 - 2.4e-15 55.9 38.2 9.1e-05 23.0 1.0 7.9 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003765.1_10 - 2.6e-11 43.5 29.6 0.00022 21.3 3.2 5.3 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003765.1_10 - 3.6e-11 42.9 15.1 0.0021 18.6 0.2 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003765.1_10 - 1.1e-10 40.7 16.4 0.019 15.0 0.1 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003765.1_10 - 9.6e-05 22.7 44.0 0.061 14.0 1.4 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003765.1_10 - 0.00047 19.9 32.4 1.4 8.9 0.4 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003765.1_10 - 0.00076 18.8 11.9 0.2 10.8 6.3 3.5 1 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003765.1_10 - 0.028 14.6 4.1 0.36 11.1 0.7 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AAAP01003765.1_10 - 0.1 13.0 27.8 0.1 13.0 8.6 4.5 3 1 2 5 5 4 0 Bacterial transcriptional activator domain NARP1 PF12569.8 AAAP01003765.1_10 - 0.17 10.7 0.3 18 4.1 0.1 2.9 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 AAAP01003765.1_10 - 2.1 8.2 7.2 2 8.3 1.1 3.3 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal CoA_transf_3 PF02515.17 AAAP01003765.1_11 - 8.9e-133 442.9 0.1 1e-132 442.7 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_42C PF08533.10 AAAP01003765.1_11 - 0.049 13.4 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain NMO PF03060.15 AAAP01003765.1_14 - 2.3e-41 142.3 6.0 3.4e-40 138.4 6.0 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 AAAP01003765.1_14 - 2.3e-07 30.1 5.0 4e-07 29.4 5.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 AAAP01003765.1_14 - 6.4e-05 22.4 6.4 6.5e-05 22.4 5.0 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 AAAP01003765.1_14 - 0.00012 21.2 1.0 0.00096 18.2 0.9 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 AAAP01003765.1_14 - 0.0005 19.6 0.3 0.00086 18.8 0.3 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.17 AAAP01003765.1_14 - 0.00073 18.8 4.8 0.0061 15.7 5.6 1.9 1 1 1 2 2 2 1 Conserved region in glutamate synthase Trp_syntA PF00290.20 AAAP01003765.1_14 - 0.002 17.0 0.2 0.0078 15.1 0.3 1.9 2 0 0 2 2 2 1 Tryptophan synthase alpha chain FlpD PF02662.16 AAAP01003765.1_14 - 0.11 12.4 0.9 2.7 8.0 0.1 2.4 1 1 1 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF1729 PF08354.10 AAAP01003765.1_14 - 0.2 10.6 1.9 0.48 9.3 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) 4HBT PF03061.22 AAAP01003765.1_15 - 8.3e-09 35.7 0.4 1.1e-08 35.2 0.4 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAAP01003765.1_15 - 0.0096 16.2 0.0 0.016 15.4 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 AAAP01003765.1_15 - 0.071 13.3 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) ABC_tran PF00005.27 AAAP01003765.1_16 - 1.1e-24 87.5 0.0 1.5e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003765.1_16 - 7.3e-09 35.9 0.1 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003765.1_16 - 5.4e-06 27.0 0.3 7.8e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003765.1_16 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AAAP01003765.1_16 - 0.0012 18.7 1.2 0.0046 16.7 1.2 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003765.1_16 - 0.0025 17.3 0.4 0.021 14.3 0.1 2.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AAAP01003765.1_16 - 0.0027 17.3 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01003765.1_16 - 0.0078 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 AAAP01003765.1_16 - 0.0087 16.0 0.5 0.014 15.3 0.5 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 AAAP01003765.1_16 - 0.011 16.2 0.1 0.016 15.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 AAAP01003765.1_16 - 0.035 12.9 1.5 0.098 11.4 1.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 AAAP01003765.1_16 - 0.081 13.2 0.2 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 AAAP01003765.1_16 - 0.081 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 AAAP01003765.1_16 - 0.082 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 AAAP01003765.1_16 - 0.14 12.4 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAAP01003765.1_16 - 0.14 11.2 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 AAAP01003765.1_16 - 0.17 12.3 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AAAP01003765.1_16 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 AAAP01003765.1_16 - 0.27 10.8 0.9 0.3 10.6 0.9 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain BCA_ABC_TP_C PF12399.8 AAAP01003765.1_17 - 4.4e-07 29.7 0.0 9.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter ABC_tran PF00005.27 AAAP01003765.1_18 - 3.2e-20 73.1 0.0 3.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01003765.1_18 - 3.8e-06 26.5 0.3 6.6e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01003765.1_18 - 0.0001 22.2 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003765.1_18 - 0.00016 22.3 0.1 0.00029 21.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAAP01003765.1_18 - 0.00074 19.2 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003765.1_18 - 0.026 15.0 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AAAP01003765.1_18 - 0.032 14.3 0.3 0.067 13.3 0.3 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01003765.1_18 - 0.036 14.0 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AAAP01003765.1_18 - 0.044 13.5 0.3 0.075 12.7 0.2 1.4 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 AAAP01003765.1_18 - 0.048 13.1 0.1 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 AAAP01003765.1_18 - 0.06 12.5 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 AAAP01003765.1_18 - 0.091 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 AAAP01003765.1_18 - 0.11 12.0 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 AAAP01003765.1_18 - 0.16 11.5 0.4 0.29 10.7 0.1 1.4 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 AAAP01003765.1_18 - 0.16 12.0 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE BPD_transp_2 PF02653.16 AAAP01003765.1_19 - 7.5e-19 67.9 10.1 9.4e-19 67.6 10.1 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component OapA_N PF08525.11 AAAP01003765.1_19 - 9.3 6.3 8.0 0.53 10.3 0.4 2.9 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif Cadherin_5 PF17892.1 AAAP01003766.1_1 - 3.9e-29 100.5 23.5 2.8e-22 78.5 7.8 6.9 7 0 0 7 7 7 2 Cadherin-like domain Big_9 PF17963.1 AAAP01003766.1_1 - 3.7e-26 91.7 33.1 3.3e-17 63.0 11.1 10.7 5 3 3 9 9 9 2 Bacterial Ig domain AFP_2 PF18815.1 AAAP01003766.1_1 - 6.3e-25 87.2 3.2 6.3e-25 87.2 3.2 8.4 8 0 0 8 8 8 1 Bacterial antifreeze protein repeat Cadherin_4 PF17803.1 AAAP01003766.1_1 - 4.2e-12 46.5 33.0 2.4e-07 31.3 9.4 12.4 10 4 0 10 10 10 4 Bacterial cadherin-like domain HemolysinCabind PF00353.19 AAAP01003766.1_1 - 1.2e-09 38.0 26.9 5.5e-08 32.6 12.3 13.1 11 3 2 13 13 13 4 RTX calcium-binding nonapeptide repeat (4 copies) Cadherin_3 PF16184.5 AAAP01003766.1_1 - 0.0043 17.0 6.3 0.16 12.0 0.0 4.2 4 1 0 4 4 4 1 Cadherin-like LptE PF04390.12 AAAP01003766.1_1 - 0.033 14.9 1.7 1.6 9.4 0.3 3.1 2 1 0 2 2 2 0 Lipopolysaccharide-assembly RGI_lyase PF18370.1 AAAP01003766.1_1 - 0.078 13.3 2.1 1.3 9.4 0.1 3.3 3 0 0 3 3 3 0 Rhamnogalacturonan I lyases beta-sheet domain Surp PF01805.20 AAAP01003766.1_1 - 0.22 11.6 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Surp module Pkinase PF00069.25 AAAP01003766.1_2 - 2.1e-31 109.3 0.0 3.7e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAAP01003766.1_2 - 2.7e-18 66.2 0.0 1.8e-16 60.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AAAP01003766.1_2 - 0.00015 21.8 1.4 0.0037 17.2 0.0 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 AAAP01003766.1_2 - 0.0043 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 AAAP01003766.1_2 - 0.048 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Flg_bb_rod PF00460.20 AAAP01003766.1_3 - 2.2e-05 24.3 2.0 3.1e-05 23.8 1.1 1.7 2 0 0 2 2 2 1 Flagella basal body rod protein Nuc_deoxyrib_tr PF05014.15 AAAP01003766.1_4 - 1.1e-42 145.1 0.0 1.6e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 AAAP01003766.1_4 - 0.0037 17.5 0.0 0.0063 16.8 0.0 1.5 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like HATPase_c PF02518.26 AAAP01003766.1_5 - 7.6e-25 87.6 0.0 1.6e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003766.1_5 - 4.7e-12 45.8 0.8 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003766.1_5 - 1.2e-11 44.8 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AAAP01003766.1_5 - 0.0044 16.9 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAAP01003766.1_5 - 0.0095 15.9 0.0 0.026 14.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AAAP01003766.1_5 - 0.017 15.2 0.0 0.16 12.2 0.0 2.4 1 1 0 1 1 1 0 PAS fold PAS_3 PF08447.12 AAAP01003766.1_5 - 0.093 13.0 0.0 3.9 7.8 0.0 2.5 2 0 0 2 2 2 0 PAS fold MCPsignal PF00015.21 AAAP01003766.1_6 - 7.4e-32 110.5 50.4 1.9e-31 109.2 26.0 3.4 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003766.1_6 - 0.00049 20.3 26.6 0.24 11.7 2.7 6.6 4 3 3 7 7 7 3 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 AAAP01003766.1_6 - 0.0012 18.6 6.8 0.0012 18.6 6.8 3.9 2 1 2 4 4 4 1 Laminin Domain I HAMP PF00672.25 AAAP01003766.1_6 - 0.0061 16.9 4.6 0.058 13.8 0.0 4.6 4 1 0 4 4 4 1 HAMP domain DUF1664 PF07889.12 AAAP01003766.1_6 - 0.0087 16.1 17.2 0.081 13.0 2.7 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF1664) Grg1 PF11034.8 AAAP01003766.1_6 - 0.073 13.3 0.1 0.073 13.3 0.1 3.4 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 DUF3450 PF11932.8 AAAP01003766.1_6 - 0.19 11.0 31.0 0.2 10.9 5.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 AAAP01003766.1_6 - 0.33 10.1 10.7 0.58 9.4 2.4 2.8 3 0 0 3 3 3 0 TMPIT-like protein AIP3 PF03915.13 AAAP01003766.1_6 - 0.5 9.4 23.0 0.065 12.3 1.5 3.2 2 1 1 3 3 3 0 Actin interacting protein 3 zf-C4H2 PF10146.9 AAAP01003766.1_6 - 7.3 6.8 12.0 0.26 11.6 0.2 3.0 3 1 1 4 4 4 0 Zinc finger-containing protein 4HB_MCP_1 PF12729.7 AAAP01003766.1_6 - 7.9 6.0 27.2 0.092 12.3 8.2 4.6 3 2 2 5 5 5 0 Four helix bundle sensory module for signal transduction RF-1 PF00472.20 AAAP01003766.1_7 - 2.1e-08 34.1 0.1 2.3e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 RF-1 domain RF-1 PF00472.20 AAAP01003766.1_8 - 6.8e-27 93.7 0.5 8.5e-27 93.4 0.5 1.0 1 0 0 1 1 1 1 RF-1 domain TonB_2 PF13103.6 AAAP01003766.1_8 - 0.14 12.4 0.2 12 6.2 0.0 2.7 2 1 1 3 3 3 0 TonB C terminal DUF1476 PF07345.11 AAAP01003766.1_9 - 4.3e-08 33.5 0.0 5.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta ETF_alpha PF00766.19 AAAP01003767.1_1 - 8.9e-37 125.0 0.4 8.9e-37 125.0 0.4 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 AAAP01003767.1_1 - 2e-23 83.2 2.4 4.3e-23 82.1 2.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain 3HCDH_N PF02737.18 AAAP01003767.1_2 - 1.4e-64 217.3 0.5 1.7e-64 217.0 0.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 AAAP01003767.1_2 - 2.6e-34 117.7 0.0 1.1e-33 115.7 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AAAP01003767.1_2 - 1.4e-06 28.6 0.7 2.8e-06 27.6 0.7 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01003767.1_2 - 0.00059 19.2 0.7 0.0011 18.3 0.4 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01003767.1_2 - 0.00089 18.9 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AAAP01003767.1_2 - 0.0013 19.3 0.9 0.0023 18.5 0.9 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAAP01003767.1_2 - 0.0016 18.7 0.2 0.0028 17.9 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 AAAP01003767.1_2 - 0.0023 17.9 0.1 0.0044 17.0 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.6 AAAP01003767.1_2 - 0.014 15.0 0.3 0.019 14.5 0.3 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.23 AAAP01003767.1_2 - 0.018 15.2 1.8 0.12 12.4 1.8 2.1 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 AAAP01003767.1_2 - 0.031 13.9 0.4 0.052 13.2 0.4 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AAAP01003767.1_2 - 0.036 14.5 0.2 0.06 13.8 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.13 AAAP01003767.1_2 - 0.069 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family DFP PF04127.15 AAAP01003767.1_2 - 0.082 12.7 0.4 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein XdhC_C PF13478.6 AAAP01003767.1_2 - 0.12 12.8 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 AAAP01003767.1_2 - 0.15 12.4 0.7 1 9.6 0.1 2.2 1 1 1 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 AAAP01003767.1_2 - 0.17 12.0 0.6 0.3 11.1 0.6 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TarH PF02203.15 AAAP01003767.1_3 - 1.6e-16 60.7 1.0 1.9e-16 60.5 1.0 1.1 1 0 0 1 1 1 1 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.7 AAAP01003767.1_3 - 1.6e-15 57.1 0.0 2e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF4811 PF16069.5 AAAP01003767.1_3 - 0.036 13.9 0.6 0.057 13.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) AfaD PF05775.12 AAAP01003767.1_3 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein MCPsignal PF00015.21 AAAP01003767.1_4 - 6.3e-32 110.8 42.0 6.4e-31 107.5 27.0 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003767.1_4 - 0.00093 19.4 19.4 0.12 12.7 3.2 4.3 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003767.1_4 - 0.0019 18.2 12.7 0.19 11.8 1.1 3.8 2 2 1 3 3 3 3 Protein of unknown function (DUF1664) HAMP PF00672.25 AAAP01003767.1_4 - 0.0054 17.1 0.4 0.0054 17.1 0.4 4.2 4 0 0 4 4 4 1 HAMP domain Mur_ligase_C PF02875.21 AAAP01003767.1_4 - 0.0061 16.8 2.5 0.36 11.1 0.0 3.6 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Nup88 PF10168.9 AAAP01003767.1_4 - 0.065 11.0 2.1 0.11 10.3 2.1 1.3 1 0 0 1 1 1 0 Nuclear pore component IFT57 PF10498.9 AAAP01003767.1_4 - 0.19 10.7 5.9 0.96 8.3 0.7 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 FliJ PF02050.16 AAAP01003767.1_4 - 0.29 11.4 13.4 1.6 9.0 4.8 3.0 1 1 1 3 3 3 0 Flagellar FliJ protein Syntaxin_2 PF14523.6 AAAP01003767.1_4 - 0.31 11.4 5.2 4.4 7.7 0.4 3.7 2 2 1 3 3 3 0 Syntaxin-like protein DUF3450 PF11932.8 AAAP01003767.1_4 - 1 8.6 18.8 0.033 13.5 2.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 AAAP01003767.1_4 - 1.2 9.6 8.5 11 6.6 0.2 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.13 AAAP01003767.1_4 - 1.3 7.6 6.5 0.37 9.4 1.2 2.1 2 0 0 2 2 2 0 Tweety Serine_rich PF08824.10 AAAP01003767.1_4 - 2.1 8.3 8.3 1.2 9.1 3.4 2.8 1 1 1 3 3 3 0 Serine rich protein interaction domain COG2 PF06148.11 AAAP01003767.1_4 - 2.8 8.0 10.7 7.5 6.7 2.3 4.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 T3SS_basalb_I PF17001.5 AAAP01003767.1_4 - 3.1 8.5 13.1 0.82 10.3 2.4 3.4 1 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF2894 PF11445.8 AAAP01003767.1_4 - 3.2 8.2 13.3 1.7 9.1 7.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2894) TACC_C PF05010.14 AAAP01003767.1_4 - 3.5 7.3 11.3 2.2 8.0 5.2 3.1 2 2 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ISG65-75 PF11727.8 AAAP01003767.1_4 - 5.2 6.2 18.8 5.3 6.2 3.6 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein TMPIT PF07851.13 AAAP01003767.1_4 - 9.1 5.4 5.5 15 4.7 1.4 2.3 1 1 0 2 2 2 0 TMPIT-like protein SecA_DEAD PF07517.14 AAAP01003767.1_5 - 5.5e-133 442.7 0.9 5.5e-133 442.7 0.9 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain SecA_SW PF07516.13 AAAP01003767.1_5 - 1.4e-64 217.9 7.9 1.4e-64 217.9 7.9 2.5 3 1 0 3 3 3 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AAAP01003767.1_5 - 8.1e-39 132.7 2.2 3.4e-38 130.7 0.6 2.7 2 0 0 2 2 2 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AAAP01003767.1_5 - 2.2e-10 40.2 8.2 3.6e-10 39.6 8.2 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 AAAP01003767.1_5 - 8.8e-05 22.3 0.1 0.00038 20.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AAAP01003767.1_5 - 0.0016 18.8 0.3 0.017 15.4 0.2 2.4 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 AAAP01003767.1_5 - 0.076 13.4 0.2 0.4 11.0 0.2 2.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain MCPsignal PF00015.21 AAAP01003767.1_6 - 1.6e-36 125.7 18.6 1.6e-36 125.7 18.6 2.9 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_3 PF14827.6 AAAP01003767.1_6 - 9e-27 94.3 0.6 2.5e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Double sensory domain of two-component sensor kinase CZB PF13682.6 AAAP01003767.1_6 - 1.8e-11 44.3 0.1 4.7e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain HAMP PF00672.25 AAAP01003767.1_6 - 9.1e-10 38.8 1.0 9.1e-10 38.8 1.0 4.0 3 0 0 3 3 3 1 HAMP domain NPV_P10 PF05531.12 AAAP01003767.1_6 - 0.038 14.5 2.4 21 5.7 0.1 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AAAP01003767.1_6 - 0.11 12.8 8.4 4.4 7.7 0.0 4.6 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 AAAP01003767.1_6 - 0.39 10.8 9.7 6 6.9 0.0 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) dCache_1 PF02743.18 AAAP01003767.1_6 - 0.53 10.0 2.0 13 5.4 0.0 3.0 2 1 1 3 3 3 0 Cache domain FH2 PF02181.23 AAAP01003767.1_6 - 1.4 8.0 4.0 5 6.1 1.1 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain Laminin_II PF06009.12 AAAP01003767.1_6 - 3.8 7.5 14.2 0.2 11.6 1.8 3.7 4 1 1 5 5 5 0 Laminin Domain II RNA_pol_Rpb2_6 PF00562.28 AAAP01003768.1_1 - 2.7e-85 286.8 0.3 3.7e-85 286.4 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 AAAP01003768.1_1 - 7.9e-28 96.7 0.0 1.4e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb1_1 PF04997.12 AAAP01003768.1_2 - 7e-91 304.8 0.0 1.2e-90 304.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AAAP01003768.1_2 - 2.1e-74 250.4 0.1 4.9e-74 249.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AAAP01003768.1_2 - 1.1e-37 129.8 0.0 4.5e-27 95.3 0.0 2.8 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AAAP01003768.1_2 - 2.8e-23 82.6 0.3 3.4e-22 79.0 0.3 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AAAP01003768.1_2 - 1.1e-17 64.0 0.4 2.6e-17 62.7 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.22 AAAP01003768.1_2 - 6.8e-07 29.4 0.2 0.047 13.9 0.0 4.5 4 1 0 4 4 4 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 AAAP01003768.1_2 - 5.4e-06 26.1 0.0 0.28 11.1 0.0 4.1 4 0 0 4 4 4 2 Biotin-lipoyl like Apocytochr_F_C PF01333.19 AAAP01003768.1_2 - 9.6e-06 25.6 0.0 0.13 12.3 0.0 3.0 3 0 0 3 3 3 2 Apocytochrome F, C-terminal PTS_EIIA_1 PF00358.20 AAAP01003768.1_2 - 0.00061 19.6 0.0 26 4.6 0.0 5.1 4 0 0 4 4 4 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF758 PF05527.11 AAAP01003768.1_2 - 0.14 12.2 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Biotin_lipoyl PF00364.22 AAAP01003768.1_2 - 0.66 9.9 4.5 21 5.0 0.0 4.0 5 0 0 5 5 5 0 Biotin-requiring enzyme Sel1 PF08238.12 AAAP01003768.1_3 - 2.9e-11 43.7 7.0 0.0026 18.4 0.3 3.7 3 0 0 3 3 3 3 Sel1 repeat Trypsin_2 PF13365.6 AAAP01003768.1_3 - 9.2e-07 29.9 0.0 1.7e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin_2 PF13365.6 AAAP01003768.1_4 - 6.1e-07 30.4 0.1 6.9e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAAP01003768.1_4 - 0.027 14.3 0.0 0.029 14.2 0.0 1.0 1 0 0 1 1 1 0 Trypsin SLT PF01464.20 AAAP01003768.1_5 - 2.1e-06 27.4 0.0 2.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Transglycosylase SLT domain Phage_lysozyme2 PF18013.1 AAAP01003768.1_5 - 0.0025 17.8 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Phage tail lysozyme Ribosom_S12_S23 PF00164.25 AAAP01003768.1_6 - 3.7e-42 142.6 0.7 4.2e-42 142.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 AAAP01003768.1_6 - 0.15 12.8 0.0 0.33 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 Ribosomal_S7 PF00177.21 AAAP01003768.1_7 - 7.9e-69 230.0 1.7 8.9e-69 229.9 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nup153 PF08604.10 AAAP01003768.1_7 - 0.14 11.0 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like GTP_EFTU PF00009.27 AAAP01003768.1_8 - 2.9e-70 235.8 0.0 4.3e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AAAP01003768.1_8 - 2.6e-43 146.7 0.2 5e-43 145.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AAAP01003768.1_8 - 2.3e-33 114.1 0.1 5.1e-33 113.0 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AAAP01003768.1_8 - 3.2e-32 110.4 0.6 8.8e-32 109.0 0.1 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAAP01003768.1_8 - 1.3e-15 57.5 1.1 4.5e-15 55.8 0.2 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AAAP01003768.1_8 - 8.6e-05 22.4 0.1 0.00019 21.3 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AAAP01003768.1_8 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 AAAP01003768.1_8 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ANP PF00212.18 AAAP01003768.1_8 - 0.099 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Atrial natriuretic peptide GTP_EFTU PF00009.27 AAAP01003768.1_9 - 5.2e-56 189.3 0.0 6.3e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AAAP01003768.1_9 - 4.4e-06 26.7 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 AAAP01003768.1_9 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AAAP01003768.1_9 - 0.064 13.1 0.0 0.2 11.6 0.0 1.7 1 1 1 2 2 2 0 RsgA GTPase bMG10 PF17973.1 AAAP01003769.1_2 - 5.3e-26 91.3 0.1 1.8e-24 86.4 0.0 3.1 3 0 0 3 3 3 1 Bacterial Alpha-2-macroglobulin MG10 domain MG2 PF01835.19 AAAP01003769.1_2 - 3.5e-18 65.9 0.2 1e-12 48.3 0.0 5.5 5 0 0 5 5 5 1 MG2 domain A2M_BRD PF07703.14 AAAP01003769.1_2 - 6.9e-17 62.1 0.0 2.3e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 AAAP01003769.1_2 - 4.7e-16 58.4 0.2 3.8e-11 42.7 0.0 3.6 4 0 0 4 4 4 2 Alpha-2-macroglobulin family bMG3 PF11974.8 AAAP01003769.1_2 - 7e-09 35.6 1.0 1.7e-06 28.0 0.1 3.6 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 AAAP01003769.1_2 - 5.4e-07 29.5 5.3 0.13 12.3 0.6 4.3 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 1) bMG6 PF17962.1 AAAP01003769.1_2 - 4.1e-06 26.9 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial macroglobulin domain 6 CarboxypepD_reg PF13620.6 AAAP01003769.1_2 - 0.0028 17.9 0.4 0.25 11.6 0.1 3.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 AAAP01003769.1_2 - 0.007 16.8 0.5 0.69 10.2 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4198) Big_5 PF13205.6 AAAP01003769.1_2 - 0.0078 16.9 0.0 5.1 7.9 0.0 3.5 2 1 1 3 3 3 1 Bacterial Ig-like domain CopC PF04234.12 AAAP01003769.1_2 - 0.016 16.2 0.7 2.1 9.4 0.0 4.6 5 0 0 5 5 5 0 CopC domain Big_10 PF17964.1 AAAP01003769.1_2 - 0.019 15.0 0.3 0.072 13.1 0.3 2.0 1 0 0 1 1 1 0 Bacterial Ig domain MG4 PF17789.1 AAAP01003769.1_2 - 0.023 14.8 0.5 14 5.9 0.1 4.0 4 0 0 4 4 4 0 Macroglobulin domain MG4 Transgly PF00912.22 AAAP01003769.1_3 - 1.2e-43 148.7 0.0 1.7e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AAAP01003769.1_3 - 8.1e-12 44.9 0.0 1.8e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain Ub-RnfH PF03658.14 AAAP01003770.1_2 - 1.4e-35 121.5 0.0 1.6e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin Ub-Mut7C PF14451.6 AAAP01003770.1_2 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Mut7-C ubiquitin SLBB PF10531.9 AAAP01003770.1_2 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 SLBB domain EppA_BapA PF07268.11 AAAP01003770.1_2 - 0.14 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Kei1 PF08552.11 AAAP01003770.1_3 - 0.34 10.8 4.2 0.41 10.5 4.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Na_H_Exchanger PF00999.21 AAAP01003770.1_4 - 2.3e-16 59.6 19.2 3e-16 59.2 19.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 AAAP01003770.1_5 - 1.6e-16 60.1 15.9 1.9e-16 59.8 15.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SpoVS PF04232.12 AAAP01003770.1_5 - 0.14 11.9 0.3 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) Toxin_30 PF08117.11 AAAP01003770.1_5 - 0.35 11.2 4.9 0.59 10.4 4.9 1.3 1 0 0 1 1 1 0 Ptu family BPD_transp_1 PF00528.22 AAAP01003770.1_6 - 2.8e-13 50.0 18.8 2.8e-13 50.0 18.8 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AAAP01003770.1_7 - 6.4e-17 61.9 13.7 6.4e-17 61.9 13.7 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01003770.1_8 - 7.2e-34 117.3 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AAAP01003770.1_8 - 1e-18 67.3 0.0 2.9e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 AAAP01003770.1_8 - 4.3e-05 23.5 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003770.1_8 - 5.8e-05 22.6 0.1 0.00054 19.5 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain CysA_C_terminal PF17850.1 AAAP01003770.1_8 - 0.0056 17.2 0.0 0.025 15.1 0.0 2.2 2 0 0 2 2 2 1 CysA C-terminal regulatory domain AAA_16 PF13191.6 AAAP01003770.1_8 - 0.0058 17.0 0.1 0.012 16.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 AAAP01003770.1_8 - 0.01 16.1 0.4 0.022 15.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003770.1_8 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 AAAP01003770.1_8 - 0.013 15.8 0.3 0.064 13.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003770.1_8 - 0.015 14.9 0.2 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AAAP01003770.1_8 - 0.022 15.2 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAAP01003770.1_8 - 0.078 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003770.1_8 - 0.18 12.3 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003770.1_8 - 0.18 11.7 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 NACHT domain SBP_bac_8 PF13416.6 AAAP01003770.1_9 - 7.7e-39 134.2 1.8 9.4e-39 133.9 1.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAAP01003770.1_9 - 2e-25 89.6 0.1 2.8e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01003770.1_9 - 2.6e-18 67.0 7.0 3.7e-18 66.5 7.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAAP01003770.1_9 - 6.4e-11 42.4 0.6 1.3e-10 41.4 0.5 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Lipoprotein_8 PF02030.15 AAAP01003770.1_9 - 0.00025 19.9 1.0 0.011 14.5 0.1 2.1 2 0 0 2 2 2 2 Hypothetical lipoprotein (MG045 family) SSF PF00474.17 AAAP01003770.1_10 - 3.1e-95 319.4 27.9 3.1e-95 319.4 27.9 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2818 PF10993.8 AAAP01003770.1_10 - 0.027 15.0 3.4 0.1 13.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) PepSY_2 PF13670.6 AAAP01003770.1_10 - 6.2 6.9 7.3 3.2 7.8 0.5 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF485 PF04341.12 AAAP01003770.1_11 - 1.1e-31 108.6 0.0 1.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 DUF1345 PF07077.11 AAAP01003770.1_11 - 0.066 12.9 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) dCache_2 PF08269.11 AAAP01003770.1_12 - 9.1e-55 185.9 0.0 1.3e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Cache domain sCache_2 PF17200.4 AAAP01003770.1_12 - 5.5e-52 175.7 0.0 1.4e-30 106.2 0.0 2.5 1 1 1 2 2 2 2 Single Cache domain 2 Cache_3-Cache_2 PF17201.4 AAAP01003770.1_12 - 1e-24 87.3 0.0 1.3e-15 57.4 0.0 2.3 1 1 1 2 2 2 2 Cache 3/Cache 2 fusion domain Response_reg PF00072.24 AAAP01003770.1_12 - 7.1e-16 58.4 0.0 1.6e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003770.1_12 - 1.6e-14 54.3 0.0 3.8e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003770.1_12 - 4.7e-14 52.6 0.1 2.8e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold HAMP PF00672.25 AAAP01003770.1_12 - 1.9e-13 50.6 0.8 7.6e-13 48.6 0.8 2.2 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AAAP01003770.1_12 - 1.1e-08 35.0 0.3 5.6e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 AAAP01003770.1_12 - 5.7e-07 29.6 0.1 0.00022 21.1 0.0 3.0 2 1 1 3 3 3 1 Cache domain sCache_3_2 PF17203.4 AAAP01003770.1_12 - 0.0014 18.8 0.2 1.3 9.2 0.0 3.0 3 0 0 3 3 3 1 Single cache domain 3 HATPase_c_2 PF13581.6 AAAP01003770.1_12 - 0.0056 16.6 0.0 0.023 14.7 0.0 2.0 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain PAS PF00989.25 AAAP01003770.1_12 - 0.015 15.3 0.0 0.081 12.9 0.0 2.4 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.7 AAAP01003770.1_12 - 0.079 13.0 0.1 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 PAS domain Response_reg PF00072.24 AAAP01003770.1_13 - 1.2e-25 89.8 0.0 1.8e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003770.1_13 - 5.8e-19 67.9 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal AMP-binding PF00501.28 AAAP01003770.1_14 - 2.4e-92 309.7 0.1 2.9e-92 309.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003770.1_14 - 7.5e-21 74.9 0.0 1.5e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ETF PF01012.21 AAAP01003770.1_15 - 1.2e-12 48.1 0.2 1.3e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain NapD PF03927.13 AAAP01003771.1_1 - 1.3e-25 89.3 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 NapD protein Molybdopterin PF00384.22 AAAP01003771.1_2 - 3.5e-91 306.3 0.1 4.3e-91 306.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003771.1_2 - 1.2e-27 96.1 0.0 5.2e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003771.1_2 - 1.9e-18 66.2 1.1 4.5e-18 65.0 0.5 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AAAP01003771.1_2 - 0.00042 20.1 3.8 0.001 18.8 3.8 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AAAP01003771.1_2 - 0.058 12.7 2.2 0.12 11.8 2.2 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_7 PF12838.7 AAAP01003771.1_3 - 4.1e-12 46.5 24.8 1.6e-06 28.5 7.8 2.8 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003771.1_3 - 1e-10 41.2 33.6 6.7e-05 22.8 1.7 4.6 4 1 0 4 4 4 4 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003771.1_3 - 9e-10 38.0 33.3 0.00018 21.2 1.6 4.7 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003771.1_3 - 7.6e-09 35.6 24.3 0.00016 21.7 9.1 3.5 1 1 4 5 5 5 5 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003771.1_3 - 5.4e-08 32.5 31.3 0.0093 16.0 2.8 4.5 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003771.1_3 - 2.4e-07 30.8 29.2 0.011 15.9 11.0 3.5 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003771.1_3 - 5.2e-07 29.7 35.3 0.014 15.9 0.5 4.5 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003771.1_3 - 1.9e-05 25.1 22.3 0.0068 16.9 0.1 3.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003771.1_3 - 3.6e-05 24.6 27.4 0.097 13.6 0.4 4.1 2 1 1 3 3 3 3 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003771.1_3 - 0.00054 20.0 27.6 0.0076 16.4 9.3 3.5 1 1 4 5 5 5 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003771.1_3 - 0.0014 19.1 25.8 0.025 15.0 1.3 3.9 1 1 4 5 5 5 4 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003771.1_3 - 0.011 16.6 41.1 0.11 13.5 5.8 4.6 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003771.1_3 - 0.61 10.3 0.1 0.61 10.3 0.1 4.0 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAAP01003771.1_3 - 1.6 8.5 18.6 0.94 9.3 4.0 3.1 2 1 1 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_22 PF17179.4 AAAP01003771.1_3 - 4 8.4 23.5 8.6 7.3 0.3 3.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_5 PF12801.7 AAAP01003771.1_4 - 8.4e-16 57.7 7.6 1.3e-12 47.5 0.4 3.6 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003771.1_4 - 1.4e-08 34.7 9.9 0.0001 22.4 1.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003771.1_4 - 1.7e-06 27.6 22.3 0.013 15.3 2.4 4.2 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003771.1_4 - 4.5e-06 26.5 24.9 0.00018 21.4 3.4 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003771.1_4 - 1.5e-05 25.5 15.5 0.0019 18.8 10.5 3.4 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003771.1_4 - 2.3e-05 25.3 12.3 0.089 13.7 1.0 4.1 4 0 0 4 4 4 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003771.1_4 - 0.00013 22.0 14.6 0.0035 17.4 8.3 3.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003771.1_4 - 0.00017 21.6 14.5 0.014 15.5 12.6 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003771.1_4 - 0.0012 19.6 24.5 0.75 10.9 3.6 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Furin-like_2 PF15913.5 AAAP01003771.1_4 - 0.017 15.3 2.3 0.028 14.6 0.1 2.1 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich Fer4_2 PF12797.7 AAAP01003771.1_4 - 0.044 13.9 3.5 0.044 13.9 3.5 4.0 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003771.1_4 - 0.83 9.9 13.9 1.7 8.8 9.7 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003771.1_4 - 0.88 10.2 21.7 0.22 12.1 2.9 3.5 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003771.1_4 - 2.1 8.9 18.3 4.5 7.8 3.9 3.8 3 1 2 5 5 5 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003771.1_4 - 2.3 8.8 14.5 1.5 9.5 1.5 3.8 3 1 1 4 4 4 0 4Fe-4S dicluster domain NapB PF03892.14 AAAP01003771.1_5 - 1.9e-40 137.8 1.3 2.4e-40 137.5 1.3 1.0 1 0 0 1 1 1 1 Nitrate reductase cytochrome c-type subunit (NapB) Cytochrom_NNT PF03264.14 AAAP01003771.1_5 - 0.00026 20.8 0.5 0.00026 20.8 0.5 1.8 2 1 0 2 2 2 1 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C7 PF14522.6 AAAP01003771.1_5 - 0.0024 17.8 0.5 0.0049 16.8 0.5 1.6 1 1 0 1 1 1 1 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003771.1_5 - 0.01 15.5 2.0 0.19 11.5 2.3 2.2 1 1 1 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 AAAP01003771.1_5 - 0.016 15.7 1.3 0.043 14.3 1.2 1.7 1 1 0 1 1 1 0 Cytochrome c3 DUF3365 PF11845.8 AAAP01003771.1_5 - 0.031 14.6 0.7 0.58 10.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) Cytochrome_CBB3 PF13442.6 AAAP01003771.1_5 - 0.037 14.4 0.5 10 6.5 0.0 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_NNT PF03264.14 AAAP01003771.1_6 - 4.3e-77 257.7 0.2 5e-77 257.5 0.2 1.0 1 0 0 1 1 1 1 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C7 PF14522.6 AAAP01003771.1_6 - 3.4e-07 30.2 10.8 3.8e-05 23.6 2.1 2.6 2 1 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 AAAP01003771.1_6 - 9.9e-07 29.1 9.7 0.0024 18.3 4.0 2.3 2 0 0 2 2 2 2 Cytochrome c3 Cytochrom_CIII PF02085.16 AAAP01003771.1_6 - 6.3e-06 26.5 7.4 0.0049 17.2 2.5 2.3 2 0 0 2 2 2 2 Class III cytochrome C family Paired_CXXCH_1 PF09699.10 AAAP01003771.1_6 - 0.00056 19.6 13.4 0.03 14.1 1.9 3.3 2 2 1 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) zf-C4pol PF14260.6 AAAP01003771.1_6 - 0.009 16.5 5.5 0.7 10.4 1.0 2.6 2 1 0 2 2 2 2 C4-type zinc-finger of DNA polymerase delta C1_1 PF00130.22 AAAP01003771.1_6 - 0.14 12.0 4.0 0.22 11.5 0.2 2.5 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cytochrome_C554 PF13435.6 AAAP01003771.1_6 - 0.33 11.9 14.9 12 6.9 10.6 3.0 1 1 1 3 3 3 0 Cytochrome c554 and c-prime Defensin_5 PF18251.1 AAAP01003771.1_6 - 0.68 10.1 12.3 8.9 6.5 0.2 4.0 4 0 0 4 4 4 0 Fungal defensin Copsin DUF455 PF04305.14 AAAP01003771.1_7 - 3.9e-94 314.8 0.0 4.4e-94 314.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Phenol_Hydrox PF02332.18 AAAP01003771.1_7 - 0.022 14.3 0.0 0.06 12.9 0.0 1.9 1 1 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase AhpC-TSA PF00578.21 AAAP01003771.1_8 - 1.3e-37 128.5 0.0 1.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01003771.1_8 - 2.1e-17 63.2 0.0 2.4e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AAAP01003771.1_8 - 1.2e-05 25.4 0.0 6.6e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AAAP01003771.1_8 - 0.00034 20.2 0.0 0.00042 19.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.6 AAAP01003771.1_8 - 0.017 15.4 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like SnoaL PF07366.12 AAAP01003771.1_8 - 0.03 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase GlnE PF03710.15 AAAP01003771.1_9 - 2.1e-65 220.6 0.2 5.2e-65 219.3 0.0 1.7 2 0 0 2 2 2 1 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AAAP01003771.1_9 - 2.3e-12 47.2 0.1 9.3e-12 45.3 0.1 2.0 2 0 0 2 2 2 1 GlnD PII-uridylyltransferase DUF294 PF03445.13 AAAP01003771.1_9 - 3.9e-05 23.5 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 AAAP01003771.1_9 - 0.083 12.7 0.3 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain DUF3971 PF13116.6 AAAP01003771.1_11 - 4.2e-12 46.2 0.0 1.6e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function AsmA_2 PF13502.6 AAAP01003771.1_11 - 0.0067 16.0 2.9 5.9 6.3 0.1 3.7 2 1 1 3 3 3 3 AsmA-like C-terminal region AsmA_2 PF13502.6 AAAP01003771.1_12 - 1.6e-17 63.8 0.0 1.7e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 AsmA-like C-terminal region AsmA_1 PF13109.6 AAAP01003771.1_12 - 6.4e-09 35.6 0.0 6.7e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 AsmA-like C-terminal region DUF1013 PF06242.11 AAAP01003771.1_14 - 2.3e-64 215.6 0.1 3.4e-64 215.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1013) HTH_Tnp_ISL3 PF13542.6 AAAP01003771.1_14 - 4.6e-05 22.8 0.0 0.12 11.8 0.0 2.6 3 0 0 3 3 3 2 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AAAP01003771.1_14 - 0.11 12.4 0.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 AAAP01003771.1_14 - 0.15 11.9 0.0 26 4.7 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Crp PF00325.20 AAAP01003771.1_14 - 0.16 11.7 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family zf-ribbon_3 PF13248.6 AAAP01003772.1_5 - 0.33 10.4 3.6 0.21 11.0 0.5 2.0 2 0 0 2 2 2 0 zinc-ribbon domain AAA_30 PF13604.6 AAAP01003772.1_6 - 8.9e-22 77.7 0.0 2.5e-21 76.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAAP01003772.1_6 - 1.8e-19 69.3 0.1 3.8e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAAP01003772.1_6 - 1.8e-12 47.8 0.0 4.6e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AAAP01003772.1_6 - 1.7e-08 34.5 0.0 0.0034 17.2 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 AAAP01003772.1_6 - 2.2e-05 24.8 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 AAAP01003772.1_6 - 9.5e-05 21.7 1.7 0.0031 16.7 0.0 3.0 2 1 1 3 3 3 1 PIF1-like helicase AAA_16 PF13191.6 AAAP01003772.1_6 - 0.012 16.0 0.5 0.035 14.5 0.2 1.9 2 1 0 2 2 2 0 AAA ATPase domain UvrD_C PF13361.6 AAAP01003772.1_6 - 0.035 13.5 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF927 PF06048.11 AAAP01003772.1_7 - 1e-39 136.9 0.0 1.5e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF927) Toprim_3 PF13362.6 AAAP01003772.1_7 - 3.6e-23 81.7 0.2 1.4e-22 79.8 0.2 2.1 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAAP01003772.1_7 - 0.0019 18.6 0.0 0.0056 17.1 0.0 1.8 1 0 0 1 1 1 1 Toprim-like YozE_SAM_like PF06855.12 AAAP01003772.1_8 - 1.2e-05 25.4 0.0 1.3e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 YozE SAM-like fold TetR_N PF00440.23 AAAP01003772.1_9 - 0.31 10.9 1.4 0.83 9.5 0.7 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DNA_methylase PF00145.17 AAAP01003772.1_12 - 2.8e-12 46.6 0.0 3.2e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Phage_integrase PF00589.22 AAAP01003773.1_2 - 4.4e-28 98.2 0.1 5.2e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Phage integrase family Integrase_1 PF12835.7 AAAP01003773.1_2 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Integrase Phage_integrase PF00589.22 AAAP01003773.1_3 - 3.8e-13 49.6 0.1 4e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 Phage integrase family HATPase_c PF02518.26 AAAP01003773.1_5 - 8.1e-24 84.3 0.0 2.1e-23 83.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003773.1_5 - 7.4e-15 55.2 0.0 1.5e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003773.1_5 - 3.2e-11 43.1 0.9 4.8e-11 42.5 0.2 1.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003773.1_5 - 4.6e-07 30.0 0.0 1.6e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AAAP01003773.1_5 - 1.1e-05 25.4 0.1 3.8e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003773.1_5 - 4.5e-05 23.4 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF594 PF04578.13 AAAP01003773.1_5 - 0.15 11.6 1.5 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF594 Hemerythrin PF01814.23 AAAP01003773.1_6 - 1.2e-07 32.4 8.3 0.0023 18.6 3.2 2.3 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain ParBc_2 PF08857.11 AAAP01003773.1_6 - 0.12 12.5 0.5 1.1 9.4 0.0 2.2 2 1 0 2 2 2 0 Putative ParB-like nuclease rve PF00665.26 AAAP01003773.1_7 - 2.9e-25 88.7 0.0 5.7e-25 87.8 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 AAAP01003773.1_7 - 7.3e-22 76.9 0.2 1.7e-21 75.8 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_1 PF01527.20 AAAP01003773.1_7 - 5e-18 65.2 0.0 8.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Transposase rve_2 PF13333.6 AAAP01003773.1_7 - 0.00049 20.2 0.0 0.0028 17.8 0.0 2.2 1 1 1 2 2 2 1 Integrase core domain HTH_23 PF13384.6 AAAP01003773.1_7 - 0.0033 17.2 0.0 0.0099 15.7 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003773.1_7 - 0.04 13.9 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003773.1_7 - 0.045 13.9 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAAP01003773.1_7 - 0.13 12.4 0.3 0.47 10.6 0.1 2.1 2 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase Phage_integrase PF00589.22 AAAP01003773.1_8 - 1.7e-17 63.8 0.0 9e-17 61.4 0.0 2.0 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 AAAP01003773.1_8 - 0.00014 22.0 0.0 0.00041 20.6 0.0 1.7 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain HTH_17 PF12728.7 AAAP01003773.1_9 - 1.8e-06 28.1 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MerR_1 PF13411.6 AAAP01003773.1_9 - 0.045 13.8 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 MerR HTH family regulatory protein MarR PF01047.22 AAAP01003773.1_10 - 0.0026 17.6 0.1 0.0055 16.6 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01003773.1_10 - 0.028 14.3 0.6 0.19 11.7 0.1 2.5 3 0 0 3 3 3 0 MarR family TrmB PF01978.19 AAAP01003773.1_10 - 0.17 11.8 0.0 0.79 9.7 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HsbA PF12296.8 AAAP01003773.1_10 - 0.56 10.7 5.7 0.24 11.8 2.4 2.0 2 0 0 2 2 2 0 Hydrophobic surface binding protein A HhH-GPD PF00730.25 AAAP01003773.1_11 - 0.068 13.6 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Nic96 PF04097.14 AAAP01003773.1_11 - 0.41 9.0 2.8 0.48 8.8 2.8 1.1 1 0 0 1 1 1 0 Nup93/Nic96 ABC_tran_CTD PF16326.5 AAAP01003773.1_11 - 3.7 7.9 7.1 22 5.4 0.4 3.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain Peptidase_S78_2 PF14550.6 AAAP01003773.1_12 - 2e-24 86.0 0.1 2.9e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Putative phage serine protease XkdF Herpes_U47 PF05467.11 AAAP01003773.1_12 - 0.041 12.1 0.1 0.05 11.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Lipoprotein_18 PF06804.11 AAAP01003773.1_14 - 0.01 14.9 1.7 0.036 13.1 0.0 1.9 1 1 0 2 2 2 0 NlpB/DapX lipoprotein Lipocalin_4 PF13648.6 AAAP01003773.1_14 - 1.3 10.0 5.0 19 6.3 0.3 2.3 1 1 1 2 2 2 0 Lipocalin-like domain DEAD PF00270.29 AAAP01003774.1_1 - 4.3e-16 59.2 0.1 6.8e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01003774.1_1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 AAAP01003774.1_1 - 3.6e-05 23.7 0.0 8.5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RecG_wedge PF17191.4 AAAP01003774.1_1 - 0.0002 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 RecG wedge domain SecA_DEAD PF07517.14 AAAP01003774.1_1 - 0.003 16.9 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.6 AAAP01003774.1_1 - 0.033 13.9 3.4 0.15 11.7 3.4 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 AAAP01003774.1_1 - 0.051 12.3 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain IMS_HHH PF11798.8 AAAP01003774.1_1 - 0.086 13.2 0.0 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif Helicase_C PF00271.31 AAAP01003774.1_1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Sdh5 PF03937.16 AAAP01003774.1_2 - 5.6e-22 77.5 0.0 6.7e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF5644 PF18712.1 AAAP01003774.1_2 - 0.016 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5644) DUF2624 PF11116.8 AAAP01003774.1_2 - 0.076 13.9 0.0 0.13 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) TRCF PF03461.15 AAAP01003774.1_3 - 1.9e-25 89.1 0.0 1.5e-24 86.2 0.0 2.3 2 0 0 2 2 2 1 TRCF domain CarD_CdnL_TRCF PF02559.16 AAAP01003774.1_3 - 7.8e-24 84.2 0.0 2e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 CarD-like/TRCF domain UvrB_inter PF17757.1 AAAP01003774.1_3 - 4.6e-18 65.2 0.0 8.7e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 AAAP01003774.1_3 - 7.8e-17 61.6 0.0 2.7e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AAAP01003774.1_3 - 4.3e-16 59.2 0.3 1.2e-15 57.7 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01003774.1_3 - 1.2e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UB2H PF14814.6 AAAP01003774.1_3 - 0.0081 16.2 0.0 0.023 14.7 0.0 1.8 1 1 0 1 1 1 1 Bifunctional transglycosylase second domain AAA_22 PF13401.6 AAAP01003774.1_3 - 0.056 13.7 1.0 3.5 7.9 0.3 3.4 3 1 0 3 3 3 0 AAA domain SecA_DEAD PF07517.14 AAAP01003774.1_3 - 0.079 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain NitrOD2 PF18550.1 AAAP01003774.1_3 - 0.16 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Nitrososphaera output domain 2 Aminotran_5 PF00266.19 AAAP01003774.1_4 - 3.4e-25 88.8 0.0 4.5e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DSBA PF01323.20 AAAP01003774.1_5 - 6.9e-38 130.4 0.0 7.7e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 AAAP01003774.1_5 - 0.00082 19.4 0.0 0.091 12.8 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.6 AAAP01003774.1_5 - 0.028 14.6 0.0 0.89 9.7 0.0 2.1 1 1 0 2 2 2 0 Thioredoxin GGDEF PF00990.21 AAAP01003774.1_6 - 7.2e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAAP01003774.1_6 - 2.2e-05 24.6 0.0 0.022 14.9 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain Peripla_BP_6 PF13458.6 AAAP01003774.1_7 - 1.7e-42 146.3 0.8 2.1e-42 146.1 0.8 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01003774.1_7 - 3.7e-06 26.3 0.0 7.1e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAAP01003774.1_7 - 4.1e-06 26.0 0.0 0.0029 16.7 0.0 2.3 2 1 0 2 2 2 2 Periplasmic binding protein domain LppC PF04348.13 AAAP01003774.1_7 - 9.7e-05 21.4 0.1 0.00011 21.1 0.1 1.2 1 0 0 1 1 1 1 LppC putative lipoprotein BPD_transp_2 PF02653.16 AAAP01003774.1_8 - 4.2e-37 127.8 38.7 4.8e-37 127.6 38.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01003774.1_9 - 1.7e-30 106.1 37.8 1.7e-30 106.1 37.8 1.6 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 AAAP01003774.1_10 - 1.2e-15 58.2 0.0 1.5e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 AAAP01003774.1_10 - 3.4e-05 24.4 0.0 4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003774.1_10 - 8.7e-05 22.2 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01003774.1_10 - 0.00024 21.0 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAAP01003774.1_10 - 0.0033 17.2 0.0 0.0033 17.2 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003774.1_10 - 0.0042 16.8 0.1 0.0066 16.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003774.1_10 - 0.0059 16.5 0.0 0.0068 16.3 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AAAP01003774.1_10 - 0.011 15.2 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 AAAP01003774.1_10 - 0.019 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MukB PF04310.12 AAAP01003774.1_10 - 0.021 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 MukB N-terminal Zeta_toxin PF06414.12 AAAP01003774.1_10 - 0.023 14.0 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 AAAP01003774.1_10 - 0.029 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AAAP01003774.1_10 - 0.035 14.5 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01003774.1_10 - 0.038 14.4 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AAAP01003774.1_10 - 0.046 13.3 0.1 0.054 13.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003774.1_10 - 0.053 13.8 0.0 0.065 13.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 AAAP01003774.1_10 - 0.056 13.0 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 AAAP01003774.1_10 - 0.079 12.6 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 AAAP01003774.1_10 - 0.081 13.3 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003774.1_10 - 0.082 13.0 0.1 0.15 12.2 0.0 1.5 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 AAAP01003774.1_10 - 0.087 12.5 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01003774.1_10 - 0.099 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DLIC PF05783.11 AAAP01003774.1_10 - 0.13 11.1 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 AAAP01003774.1_10 - 0.14 12.3 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01003774.1_10 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAAP01003774.1_10 - 0.17 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 NTPase Cytochrome_CBB3 PF13442.6 AAAP01003775.1_1 - 3.2e-12 46.6 0.0 5.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003775.1_1 - 1.4e-07 32.5 0.0 2.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c PNRC PF15365.6 AAAP01003775.1_1 - 0.88 9.5 4.0 19 5.2 0.5 2.6 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif GDP_Man_Dehyd PF16363.5 AAAP01003775.1_2 - 9.6e-82 275.0 0.0 1.1e-81 274.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003775.1_2 - 4.6e-62 209.6 0.0 5.9e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003775.1_2 - 6.1e-14 51.8 0.0 1.4e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003775.1_2 - 6.8e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 AAAP01003775.1_2 - 7.6e-09 35.3 0.0 0.00019 21.0 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase 3Beta_HSD PF01073.19 AAAP01003775.1_2 - 8e-09 34.9 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01003775.1_2 - 1.5e-07 30.9 0.0 8.5e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 AAAP01003775.1_2 - 0.0045 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003775.1_2 - 0.02 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 AAAP01003775.1_2 - 0.028 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family YAcAr PF10686.9 AAAP01003775.1_2 - 0.11 12.5 0.9 4.7 7.2 0.1 3.2 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family NTP_transferase PF00483.23 AAAP01003775.1_3 - 9.9e-62 208.7 0.0 1.2e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003775.1_3 - 2.6e-11 44.1 0.1 5.2e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain RmlD_sub_bind PF04321.17 AAAP01003775.1_4 - 5.5e-92 307.9 0.0 6.3e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAAP01003775.1_4 - 5.1e-23 81.8 0.0 7.1e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003775.1_4 - 2.7e-14 53.3 0.0 5.9e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AAAP01003775.1_4 - 1.5e-07 30.8 0.2 1.7e-06 27.4 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAAP01003775.1_4 - 1.4e-06 27.5 0.0 2.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01003775.1_4 - 3.7e-06 26.3 0.0 1.1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 AAAP01003775.1_4 - 0.0015 18.4 0.0 0.0015 18.4 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 AAAP01003775.1_4 - 0.0091 15.5 0.1 0.81 9.1 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 AAAP01003775.1_4 - 0.027 14.9 0.2 0.61 10.5 0.1 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF4776 PF16003.5 AAAP01003775.1_4 - 0.16 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) zf-TFIIB PF13453.6 AAAP01003775.1_5 - 2.2e-19 68.5 1.1 3e-19 68.1 1.1 1.2 1 0 0 1 1 1 1 Transcription factor zinc-finger zinc_ribbon_9 PF14369.6 AAAP01003775.1_5 - 1.3 9.3 5.4 5.8 7.3 0.2 2.3 1 1 1 2 2 2 0 zinc-ribbon DUF1936 PF09151.10 AAAP01003775.1_5 - 4.4 7.3 5.9 2.9 7.9 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1936) SBP_bac_3 PF00497.20 AAAP01003775.1_6 - 4.5e-47 160.4 0.0 6.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 AAAP01003775.1_6 - 9.4e-22 77.6 5.5 1.8e-21 76.8 5.5 1.5 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Phosphonate-bd PF12974.7 AAAP01003775.1_6 - 0.027 14.1 0.2 0.044 13.4 0.2 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAAP01003775.1_6 - 0.041 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 NMT1/THI5 like BPD_transp_1 PF00528.22 AAAP01003775.1_7 - 1.1e-18 67.6 12.2 1.7e-18 67.0 12.2 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01003775.1_8 - 3.2e-32 111.9 0.0 4e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003775.1_8 - 1.9e-08 34.5 0.0 0.002 18.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003775.1_8 - 1.2e-07 31.4 0.1 7.7e-06 25.5 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003775.1_8 - 0.0002 21.0 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003775.1_8 - 0.00033 20.6 0.1 0.00053 19.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01003775.1_8 - 0.0004 20.8 0.1 0.00047 20.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003775.1_8 - 0.00087 19.6 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003775.1_8 - 0.0019 18.4 0.1 0.0039 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAAP01003775.1_8 - 0.0032 17.4 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 AAAP01003775.1_8 - 0.01 16.4 0.0 0.015 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAAP01003775.1_8 - 0.018 13.9 0.6 4.6 5.9 0.1 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 AAAP01003775.1_8 - 0.021 14.6 0.2 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AAAP01003775.1_8 - 0.022 15.3 0.0 0.036 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAAP01003775.1_8 - 0.024 14.4 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01003775.1_8 - 0.056 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 AAAP01003775.1_8 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 AAAP01003775.1_8 - 0.075 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 AAAP01003775.1_8 - 0.077 12.6 0.2 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAAP01003775.1_8 - 0.093 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_13 PF13166.6 AAAP01003775.1_8 - 0.095 11.3 0.0 2.7 6.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAAP01003775.1_8 - 0.14 12.4 0.2 2.5 8.4 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 AAAP01003775.1_8 - 0.15 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAAP01003775.1_8 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 AAAP01003775.1_8 - 0.16 12.4 0.1 0.42 11.0 0.1 1.7 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 AAAP01003775.1_8 - 0.16 12.4 0.1 0.76 10.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AAAP01003775.1_8 - 0.17 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Phage_holin_3_6 PF07332.11 AAAP01003775.1_9 - 0.0047 17.0 2.0 0.0055 16.7 2.0 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SAMP PF05924.11 AAAP01003775.1_11 - 0.008 15.4 0.2 0.015 14.6 0.2 1.5 1 0 0 1 1 1 1 SAMP Motif dUTPase PF00692.19 AAAP01003775.1_13 - 7.6e-07 28.9 0.0 2.6e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 dUTPase Flagellar_put PF12611.8 AAAP01003775.1_13 - 0.013 15.2 0.3 0.023 14.4 0.3 1.4 1 0 0 1 1 1 0 Putative flagellar APH PF01636.23 AAAP01003775.1_14 - 1.8e-05 24.8 4.2 3.1e-05 24.0 4.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_33 PF13671.6 AAAP01003775.1_14 - 0.024 14.8 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Phage_capsid PF05065.13 AAAP01003776.1_1 - 3e-07 30.1 0.0 3.4e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Phage capsid family DUF4703 PF15775.5 AAAP01003776.1_4 - 0.012 15.4 1.8 0.012 15.4 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) DUF3343 PF11823.8 AAAP01003776.1_6 - 0.17 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Phage_integrase PF00589.22 AAAP01003776.1_7 - 2.3e-19 69.8 0.0 5.4e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 AAAP01003776.1_7 - 1.5e-07 31.5 0.0 4.1e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_4 PF14657.6 AAAP01003776.1_7 - 0.0013 18.4 0.0 0.0013 18.4 0.0 2.5 3 0 0 3 3 3 1 Arm DNA-binding domain ShlB PF03865.13 AAAP01003776.1_8 - 8.8e-28 97.6 0.2 1.1e-27 97.4 0.2 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AAAP01003776.1_8 - 1.2e-17 63.5 0.1 2.2e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 POTRA domain, ShlB-type TPR_12 PF13424.6 AAAP01003776.1_12 - 1.8e-19 69.8 10.3 9.8e-11 41.8 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003776.1_12 - 9.5e-12 44.4 20.9 1.1e-05 25.2 0.2 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003776.1_12 - 8.1e-10 38.1 0.2 0.46 10.4 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003776.1_12 - 5.2e-08 32.4 10.6 0.56 10.5 0.6 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003776.1_12 - 9.5e-08 31.7 0.0 0.65 10.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003776.1_12 - 0.00012 21.8 4.0 0.22 11.7 0.4 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003776.1_12 - 0.00018 22.0 20.9 0.65 11.0 2.1 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003776.1_12 - 0.0017 19.0 0.8 0.0017 19.0 0.8 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_3 PF07720.12 AAAP01003776.1_12 - 0.022 14.7 0.0 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003776.1_12 - 0.37 11.3 11.3 5.7 7.5 0.1 4.9 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003776.1_12 - 2.4 9.0 29.3 5.8 7.8 0.0 7.8 7 0 0 7 7 7 0 Tetratricopeptide repeat CHAT PF12770.7 AAAP01003776.1_13 - 9.3e-59 199.2 0.2 1.6e-58 198.4 0.2 1.3 1 0 0 1 1 1 1 CHAT domain CHASE2 PF05226.11 AAAP01003776.1_15 - 8.8e-35 120.6 0.1 1.8e-34 119.6 0.0 1.4 2 0 0 2 2 2 1 CHASE2 domain Guanylate_cyc PF00211.20 AAAP01003776.1_15 - 1.5e-21 76.8 0.0 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UbiA PF01040.18 AAAP01003777.1_1 - 2.6e-40 138.3 22.8 3.5e-40 137.9 22.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4064 PF13273.6 AAAP01003777.1_1 - 0.022 15.0 0.3 0.022 15.0 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) COX1 PF00115.20 AAAP01003777.1_2 - 2.2e-61 208.0 58.7 2.2e-61 208.0 58.7 1.6 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 AAAP01003777.1_3 - 0.00074 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AAAP01003777.1_3 - 0.052 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Sigma70_r4_2 PF08281.12 AAAP01003777.1_6 - 3.3e-15 55.5 1.1 6.3e-15 54.6 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAAP01003777.1_6 - 4.5e-14 52.0 2.2 7.1e-14 51.3 2.2 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAAP01003777.1_6 - 8.2e-09 34.9 0.1 1.8e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAAP01003777.1_6 - 0.00032 20.7 0.9 0.00049 20.0 0.9 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_AsnC-type PF13404.6 AAAP01003777.1_6 - 0.0078 16.0 0.6 0.067 13.0 0.1 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAAP01003777.1_6 - 0.027 14.0 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF134 PF02001.16 AAAP01003777.1_6 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 Lipoprotein_15 PF03640.15 AAAP01003777.1_7 - 8.8e-38 127.6 8.0 6.8e-21 73.5 3.4 2.1 2 0 0 2 2 2 2 Secreted repeat of unknown function Response_reg PF00072.24 AAAP01003777.1_8 - 4.9e-22 78.2 0.1 5.7e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PEP-utilizers_C PF02896.18 AAAP01003777.1_9 - 5e-94 314.7 0.0 8.2e-94 314.0 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AAAP01003777.1_9 - 5.2e-70 236.3 0.0 5.4e-66 223.1 0.0 3.2 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AAAP01003777.1_9 - 4.7e-27 93.5 2.1 1.3e-26 92.1 2.1 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain tRNA_synt_2f PF02092.17 AAAP01003777.1_10 - 2e-205 683.8 0.0 2.5e-205 683.4 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 AAAP01003777.1_10 - 1.6e-08 34.7 0.5 4.5e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_2e PF02091.15 AAAP01003777.1_11 - 5.5e-151 501.5 0.0 6.3e-151 501.3 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit N-glycanase_C PF09113.10 AAAP01003777.1_11 - 0.0021 17.8 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal DUF1937 PF09152.10 AAAP01003777.1_11 - 0.16 12.8 0.0 0.27 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) MCPsignal PF00015.21 AAAP01003777.1_12 - 2.2e-31 109.0 30.2 4.5e-30 104.7 27.9 2.9 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PilZ PF07238.14 AAAP01003777.1_12 - 3.9e-09 36.7 0.2 8.6e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 PilZ domain Laminin_II PF06009.12 AAAP01003777.1_12 - 0.00027 21.0 6.7 0.0078 16.2 1.6 2.6 1 1 2 3 3 3 2 Laminin Domain II DUF1664 PF07889.12 AAAP01003777.1_12 - 0.0011 19.0 6.3 0.14 12.2 2.0 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003777.1_12 - 0.011 16.0 12.0 4.1 7.7 0.1 3.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Myosin_tail_1 PF01576.19 AAAP01003777.1_12 - 0.066 11.0 0.3 0.088 10.6 0.3 1.1 1 0 0 1 1 1 0 Myosin tail APG6_N PF17675.1 AAAP01003777.1_12 - 0.13 12.8 0.8 0.58 10.7 0.2 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 AAAP01003777.1_12 - 0.13 11.5 5.3 0.12 11.7 3.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-G-binding_N PF07299.11 AAAP01003777.1_12 - 0.17 12.4 2.0 0.89 10.1 0.0 2.7 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Laminin_I PF06008.14 AAAP01003777.1_12 - 0.25 11.0 8.0 0.82 9.3 4.6 2.1 1 1 1 2 2 2 0 Laminin Domain I FlgN PF05130.12 AAAP01003777.1_12 - 0.49 10.9 4.9 4 7.9 0.4 2.4 1 1 2 3 3 3 0 FlgN protein Seryl_tRNA_N PF02403.22 AAAP01003777.1_12 - 0.51 10.6 5.7 10 6.4 1.2 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SGL PF08450.12 AAAP01003778.1_1 - 0.00098 18.8 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region MCR_alpha PF02249.17 AAAP01003778.1_1 - 0.041 14.3 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Arm-DNA-bind_3 PF13356.6 AAAP01003778.1_2 - 6.7e-09 36.0 0.3 2.2e-08 34.4 0.3 1.9 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 AAAP01003778.1_2 - 2e-05 24.5 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family HTH_29 PF13551.6 AAAP01003778.1_3 - 0.013 15.5 0.6 0.65 10.1 0.0 2.9 2 1 1 3 3 3 0 Winged helix-turn helix HTH_35 PF13693.6 AAAP01003778.1_3 - 0.037 14.1 0.5 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AAAP01003778.1_3 - 0.081 12.9 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain LPD22 PF18834.1 AAAP01003778.1_3 - 0.081 13.1 0.9 0.13 12.5 0.1 1.7 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 Fe_dep_repress PF01325.19 AAAP01003778.1_3 - 0.11 12.7 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Phage_AlpA PF05930.12 AAAP01003778.1_4 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) PriCT_2 PF08707.11 AAAP01003778.1_9 - 1.9e-14 53.8 0.5 1.9e-14 53.8 0.5 2.8 3 0 0 3 3 3 1 Primase C terminal 2 (PriCT-2) Prim-Pol PF09250.11 AAAP01003778.1_9 - 4.4e-07 30.4 3.6 6.3e-07 29.9 2.2 2.0 2 0 0 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal Phasin_2 PF09361.10 AAAP01003778.1_10 - 1.6e-21 76.4 14.3 2.1e-21 76.0 14.3 1.2 1 0 0 1 1 1 1 Phasin protein DUF5344 PF17279.2 AAAP01003778.1_10 - 0.039 14.5 0.4 0.039 14.5 0.4 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Terminase_4 PF05119.12 AAAP01003778.1_11 - 4.7e-19 68.7 0.0 6.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Phage terminase, small subunit MCPsignal PF00015.21 AAAP01003778.1_12 - 1e-32 113.3 23.9 1e-32 113.3 23.9 3.6 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003778.1_12 - 5.3e-08 33.1 0.0 5.3e-08 33.1 0.0 4.4 7 0 0 7 7 6 1 HAMP domain Hemerythrin PF01814.23 AAAP01003778.1_12 - 1.6e-06 28.7 1.2 1.6e-06 28.7 1.2 4.9 6 1 1 7 7 7 1 Hemerythrin HHE cation binding domain DUF1664 PF07889.12 AAAP01003778.1_12 - 0.0059 16.6 18.5 0.0086 16.1 1.9 4.8 3 2 1 4 4 4 2 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003778.1_12 - 0.021 15.1 28.9 0.052 13.8 2.7 6.1 3 3 4 7 7 7 0 Bacterial protein of unknown function (DUF948) Dor1 PF04124.12 AAAP01003778.1_12 - 0.22 10.2 9.9 0.064 11.9 2.1 3.2 3 1 0 3 3 3 0 Dor1-like family DUF812 PF05667.11 AAAP01003778.1_12 - 0.27 10.1 17.3 0.015 14.2 10.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TACC_C PF05010.14 AAAP01003778.1_12 - 0.41 10.4 9.5 1.1 9.1 0.2 2.7 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 AAAP01003778.1_12 - 1.2 7.7 10.9 0.84 8.2 8.6 1.7 1 1 0 1 1 1 0 AAA domain AIP3 PF03915.13 AAAP01003778.1_12 - 1.9 7.5 16.1 3 6.9 7.8 2.4 1 1 1 2 2 2 0 Actin interacting protein 3 BLOC1_2 PF10046.9 AAAP01003778.1_12 - 3.2 8.1 11.9 3.2 8.1 1.3 4.9 5 2 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 kleA_kleC PF17383.2 AAAP01003778.1_12 - 7.3 7.0 10.3 0.93 9.9 0.2 3.9 2 1 2 4 4 4 0 Uncharacterized KorC regulated protein A CDC37_N PF03234.14 AAAP01003778.1_12 - 8 7.4 10.6 6.9 7.6 4.4 3.1 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding Glyco_transf_41 PF13844.6 AAAP01003779.1_1 - 1.9e-25 89.3 0.0 2.2e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 Glyco_trans_1_4 PF13692.6 AAAP01003779.1_1 - 7e-05 23.3 0.0 0.0002 21.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003779.1_1 - 0.00035 20.1 0.0 0.001 18.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 adh_short_C2 PF13561.6 AAAP01003779.1_2 - 2e-41 142.1 0.2 2.9e-41 141.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003779.1_2 - 2.5e-37 128.2 0.0 3.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 AAAP01003779.1_2 - 1e-05 25.5 0.2 1.5e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AAAP01003779.1_2 - 8.4e-05 22.5 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AAAP01003779.1_2 - 0.045 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT_7 PF13840.6 AAAP01003779.1_2 - 0.076 12.8 0.0 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 ACT domain Bac_DnaA PF00308.18 AAAP01003779.1_3 - 1.3e-05 25.2 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 2 2 Bacterial dnaA protein IstB_IS21 PF01695.17 AAAP01003779.1_3 - 0.00068 19.4 0.2 0.037 13.7 0.2 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AAAP01003779.1_3 - 0.0045 17.3 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003779.1_3 - 0.0069 16.8 2.7 0.029 14.8 2.7 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AAAP01003779.1_3 - 0.0076 16.4 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003779.1_3 - 0.089 13.2 0.0 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAAP01003779.1_3 - 0.094 12.6 0.3 0.29 11.0 0.0 1.9 2 1 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 AAAP01003779.1_3 - 0.13 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAAP01003779.1_3 - 0.24 10.8 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AI-2E_transport PF01594.16 AAAP01003779.1_4 - 1.2e-59 202.1 22.1 1.6e-59 201.7 22.1 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF5518 PF17647.1 AAAP01003779.1_4 - 0.0016 18.6 5.7 0.0016 18.6 5.7 4.3 3 1 1 4 4 4 1 Family of unknown function (DUF5518) DUF2066 PF09839.9 AAAP01003779.1_5 - 5.6e-31 107.7 0.4 8.4e-31 107.2 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2066) AIRS_C PF02769.22 AAAP01003779.1_6 - 3.6e-38 131.2 0.8 6.1e-38 130.4 0.8 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAAP01003779.1_6 - 2.9e-15 56.7 1.3 6.3e-15 55.6 1.3 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Formyl_trans_N PF00551.19 AAAP01003779.1_7 - 3.7e-59 199.5 0.0 4.2e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Glyco_transf_9 PF01075.17 AAAP01003779.1_8 - 4.2e-17 62.3 0.0 5.8e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Pribosyltran PF00156.27 AAAP01003779.1_9 - 2.3e-18 66.2 0.0 2.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AAAP01003779.1_9 - 0.0014 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PAS_7 PF12860.7 AAAP01003779.1_10 - 6.8e-42 142.3 0.0 1.5e-20 73.5 0.0 4.0 3 1 0 3 3 3 3 PAS fold HATPase_c PF02518.26 AAAP01003779.1_10 - 3.3e-28 98.4 0.0 9.1e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AAAP01003779.1_10 - 3.8e-23 81.0 1.6 4.9e-07 29.6 0.1 3.9 4 0 0 4 4 4 3 PAS domain HisKA PF00512.25 AAAP01003779.1_10 - 2e-22 79.0 10.3 1.8e-19 69.5 0.0 4.2 5 0 0 5 5 5 2 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003779.1_10 - 9.4e-19 67.5 0.1 1.3e-13 50.9 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01003779.1_10 - 4.4e-18 65.4 0.0 5.3e-14 52.3 0.0 3.7 3 2 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AAAP01003779.1_10 - 5.1e-14 52.4 0.2 9.5e-09 35.5 0.0 4.2 3 2 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.6 AAAP01003779.1_10 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003779.1_10 - 0.026 14.5 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pyridoxal_deC PF00282.19 AAAP01003779.1_12 - 7.6e-39 133.5 0.0 9.2e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Abhydrolase_6 PF12697.7 AAAP01003779.1_12 - 6.6e-05 23.6 4.8 6.6e-05 23.6 4.8 3.2 1 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003779.1_12 - 0.00013 21.7 0.0 0.0054 16.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Beta_elim_lyase PF01212.21 AAAP01003779.1_12 - 0.00025 20.5 0.1 0.00038 19.8 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase ACR_tran PF00873.19 AAAP01003780.1_1 - 1.6e-107 360.5 10.5 1.8e-107 360.3 10.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003780.1_1 - 1.2e-06 27.8 9.4 1.3e-06 27.6 9.4 1.2 1 0 0 1 1 1 1 MMPL family DUF4448 PF14610.6 AAAP01003780.1_1 - 0.03 14.1 0.4 0.059 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 AAAP01003780.1_1 - 1.3 7.7 3.6 0.65 8.7 0.6 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.11 AAAP01003780.1_1 - 1.6 8.2 6.1 1.2 8.6 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Cupredoxin_1 PF13473.6 AAAP01003780.1_2 - 1.1e-17 64.1 0.0 1.3e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Cupredoxin-like domain Peptidase_A8 PF01252.18 AAAP01003780.1_5 - 3.3e-32 111.7 0.6 4e-32 111.4 0.6 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II Gram_pos_anchor PF00746.21 AAAP01003780.1_5 - 0.025 14.5 0.6 0.76 9.8 0.2 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif SecE PF00584.20 AAAP01003780.1_5 - 0.1 12.5 5.4 0.16 11.9 0.3 2.8 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex E1-E2_ATPase PF00122.20 AAAP01003780.1_6 - 2.9e-49 167.1 0.3 2.9e-49 167.1 0.3 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01003780.1_6 - 1.5e-46 159.4 1.1 2.5e-46 158.6 1.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003780.1_6 - 9e-05 22.9 0.3 0.00075 19.9 0.3 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GGDEF_2 PF17853.1 AAAP01003780.1_6 - 0.01 16.1 0.0 0.052 13.8 0.0 2.3 1 1 0 1 1 1 0 GGDEF-like domain DUF805 PF05656.14 AAAP01003780.1_6 - 0.05 14.0 0.3 0.05 14.0 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Hydrolase_3 PF08282.12 AAAP01003780.1_6 - 0.074 12.8 1.3 0.14 11.9 1.3 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HrpB1_HrpK PF09613.10 AAAP01003780.1_6 - 0.18 11.4 1.8 0.47 10.1 0.2 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) BacA PF02673.18 AAAP01003780.1_7 - 7.3e-73 245.4 9.9 8.4e-73 245.2 9.9 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA Polysacc_synt_C PF14667.6 AAAP01003780.1_7 - 0.0013 18.8 3.0 0.0013 18.8 3.0 3.1 1 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MerR-DNA-bind PF09278.11 AAAP01003780.1_8 - 1.9e-21 76.3 4.1 2.8e-21 75.8 4.1 1.2 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 AAAP01003780.1_8 - 1.1e-17 63.9 0.1 1.8e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003780.1_8 - 6.1e-15 54.7 1.9 1.5e-14 53.4 1.8 1.7 2 0 0 2 2 2 1 MerR family regulatory protein YtzH PF14165.6 AAAP01003780.1_8 - 0.23 11.9 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 YtzH-like protein UPF0060 PF02694.15 AAAP01003780.1_9 - 7.4e-34 116.2 8.2 8.1e-34 116.1 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 AAAP01003780.1_9 - 0.012 15.8 4.3 0.044 13.9 4.3 1.9 1 1 0 1 1 1 0 EamA-like transporter family EamA PF00892.20 AAAP01003780.1_10 - 4.9e-34 117.4 31.7 4.9e-22 78.6 12.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 AAAP01003780.1_10 - 0.02 14.9 2.3 0.13 12.3 0.1 2.7 3 0 0 3 3 3 0 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 AAAP01003780.1_10 - 6.2 7.6 16.8 3.5 8.4 5.9 3.1 3 1 1 4 4 4 0 Small Multidrug Resistance protein DUF3040 PF11239.8 AAAP01003780.1_11 - 2.7 8.3 5.6 15 6.0 5.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Phage-tail_3 PF13550.6 AAAP01003780.1_13 - 3.9e-26 91.9 0.0 7.8e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Putative phage tail protein Lambda_tail_I PF06805.12 AAAP01003780.1_13 - 1e-21 77.0 1.9 1.8e-21 76.2 0.8 2.0 2 0 0 2 2 2 1 Bacteriophage lambda tail assembly protein I NLPC_P60 PF00877.19 AAAP01003780.1_14 - 4e-05 23.6 0.0 4.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family CheW PF01584.19 AAAP01003781.1_2 - 4.9e-14 52.2 0.0 6.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain CheR PF01739.18 AAAP01003781.1_3 - 1.7e-49 168.0 0.0 2.3e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain TPR_2 PF07719.17 AAAP01003781.1_3 - 1.2e-06 28.2 3.5 0.027 14.6 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003781.1_3 - 0.00014 22.4 5.4 0.061 14.2 0.5 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003781.1_3 - 0.00027 20.6 1.0 0.02 14.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003781.1_3 - 0.00067 20.3 6.5 0.0058 17.3 1.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Methyltransf_12 PF08242.12 AAAP01003781.1_3 - 0.0007 20.3 0.0 0.012 16.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003781.1_3 - 0.0036 18.0 0.0 0.51 11.1 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.6 AAAP01003781.1_3 - 0.0051 16.5 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 AAAP01003781.1_3 - 0.013 15.6 0.0 0.3 11.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003781.1_3 - 0.013 15.8 0.1 3.1 8.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003781.1_3 - 0.059 13.9 1.6 0.42 11.1 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003781.1_3 - 0.077 13.2 2.1 0.22 11.7 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003781.1_3 - 0.47 10.8 3.2 4 7.8 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003781.1_3 - 4.8 8.0 4.8 28 5.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CheW PF01584.19 AAAP01003781.1_4 - 5.7e-17 61.6 0.1 6.9e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 CheW-like domain AAA_31 PF13614.6 AAAP01003781.1_5 - 4.6e-48 163.5 0.2 7.1e-48 162.9 0.2 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01003781.1_5 - 6.6e-19 68.2 0.1 9.4e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 AAAP01003781.1_5 - 3.2e-11 43.2 0.2 1.6e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 AAAP01003781.1_5 - 1.9e-09 37.4 2.0 8e-09 35.3 1.8 2.0 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAAP01003781.1_5 - 3.7e-09 36.2 0.3 1.8e-07 30.7 0.3 2.2 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 AAAP01003781.1_5 - 4.7e-09 36.1 0.0 3.5e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAAP01003781.1_5 - 0.00039 19.7 0.3 0.0008 18.7 0.2 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase sCache_2 PF17200.4 AAAP01003781.1_6 - 1.8e-11 44.1 0.1 2.2e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003781.1_6 - 2.5e-08 33.4 0.0 3.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Cache domain MCPsignal PF00015.21 AAAP01003781.1_7 - 2.8e-30 105.4 22.0 2.8e-30 105.4 22.0 3.8 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAAP01003781.1_7 - 2.6e-09 36.9 0.1 2.6e-09 36.9 0.1 3.2 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003781.1_7 - 8.5e-09 35.7 6.0 2.2e-08 34.3 0.3 3.9 4 1 0 4 4 4 1 HAMP domain TarH PF02203.15 AAAP01003781.1_7 - 1e-05 25.6 3.9 1e-05 25.6 3.9 4.1 4 1 1 5 5 5 1 Tar ligand binding domain homologue Laminin_I PF06008.14 AAAP01003781.1_7 - 0.0014 18.4 3.6 0.0014 18.4 3.6 4.1 2 1 1 4 4 4 1 Laminin Domain I DUF1664 PF07889.12 AAAP01003781.1_7 - 0.18 11.8 10.6 4.4 7.4 0.2 4.8 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) LXG PF04740.12 AAAP01003781.1_7 - 0.43 10.3 7.4 0.68 9.6 1.5 3.2 4 1 0 4 4 4 0 LXG domain of WXG superfamily Laminin_II PF06009.12 AAAP01003781.1_7 - 1.2 9.2 17.2 0.49 10.4 3.7 3.8 1 1 2 3 3 3 0 Laminin Domain II GCN5L1 PF06320.13 AAAP01003781.1_7 - 1.5 9.0 6.9 2.7 8.2 3.8 2.8 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF948 PF06103.11 AAAP01003781.1_7 - 2.2 8.6 29.0 0.61 10.4 1.5 6.4 4 3 4 8 8 8 0 Bacterial protein of unknown function (DUF948) PAS_7 PF12860.7 AAAP01003781.1_9 - 7e-43 145.5 0.0 1.3e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold Response_reg PF00072.24 AAAP01003781.1_9 - 8.4e-28 96.8 0.0 1.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003781.1_9 - 8.5e-23 81.0 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003781.1_9 - 6e-22 77.5 1.0 1.7e-21 76.0 0.1 2.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003781.1_9 - 0.001 19.3 0.1 0.0037 17.5 0.1 2.0 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003781.1_9 - 0.031 14.3 0.1 0.097 12.7 0.1 1.9 1 0 0 1 1 1 0 PAS domain Acetyltransf_5 PF13444.6 AAAP01003781.1_10 - 2.4e-32 111.7 0.2 4e-32 110.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAAP01003781.1_10 - 0.00038 20.5 0.0 0.086 12.9 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF3953 PF13129.6 AAAP01003781.1_11 - 0.049 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) PMSR PF01625.21 AAAP01003781.1_12 - 9.8e-62 207.7 0.0 1.1e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Hemerythrin PF01814.23 AAAP01003781.1_13 - 1.3e-10 42.0 2.2 1.5e-10 41.8 2.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TetR_C_31 PF17940.1 AAAP01003781.1_13 - 0.011 15.9 0.7 0.015 15.5 0.7 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pep_deformylase PF01327.21 AAAP01003781.1_13 - 0.084 12.5 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Polypeptide deformylase BALF1 PF06861.11 AAAP01003781.1_13 - 0.099 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 BALF1 protein CheX PF13690.6 AAAP01003781.1_15 - 1.1e-09 38.3 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX Patatin PF01734.22 AAAP01003781.1_16 - 0.031 14.4 0.1 0.061 13.5 0.1 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase Hemerythrin PF01814.23 AAAP01003782.1_1 - 6.2e-13 49.5 8.9 6.8e-13 49.4 8.9 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EAL PF00563.20 AAAP01003782.1_2 - 1.9e-56 191.3 0.0 2.7e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 EAL domain PAS_4 PF08448.10 AAAP01003782.1_2 - 1.7e-08 34.7 0.0 5.6e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold GGDEF PF00990.21 AAAP01003782.1_2 - 0.03 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003782.1_2 - 0.035 14.4 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 AAAP01003782.1_2 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold GGA_N-GAT PF18308.1 AAAP01003782.1_2 - 0.16 11.7 0.7 0.53 9.9 0.0 2.2 3 0 0 3 3 3 0 GGA N-GAT domain CorA PF01544.18 AAAP01003782.1_3 - 1.7e-56 191.7 0.0 2.2e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PetG PF02529.15 AAAP01003782.1_3 - 0.061 13.2 1.4 0.12 12.3 1.4 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF5610 PF18433.1 AAAP01003782.1_3 - 0.1 13.1 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) SBP_bac_3 PF00497.20 AAAP01003782.1_4 - 0.00063 19.2 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HATPase_c PF02518.26 AAAP01003782.1_5 - 1.6e-27 96.2 0.0 4.6e-27 94.8 0.0 1.8 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE5 PF17149.4 AAAP01003782.1_5 - 9.9e-13 48.0 0.0 5.4e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Periplasmic sensor domain found in signal transduction proteins HisKA PF00512.25 AAAP01003782.1_5 - 2.1e-10 40.5 1.8 2.6e-10 40.2 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003782.1_5 - 3.9e-05 23.5 0.0 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain ApoLp-III PF07464.11 AAAP01003782.1_5 - 0.039 14.1 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Seryl_tRNA_N PF02403.22 AAAP01003782.1_5 - 0.076 13.3 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ASD2 PF08687.11 AAAP01003782.1_5 - 0.077 12.6 1.0 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 HATPase_c_3 PF13589.6 AAAP01003782.1_5 - 0.17 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APG6_N PF17675.1 AAAP01003782.1_5 - 0.25 11.9 3.7 0.35 11.4 1.5 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Col_cuticle_N PF01484.17 AAAP01003782.1_5 - 0.59 10.2 2.1 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain ZapB PF06005.12 AAAP01003782.1_5 - 0.71 10.4 3.3 0.46 11.0 0.9 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Cytochrom_D1 PF02239.16 AAAP01003782.1_7 - 9.5e-105 350.1 0.0 5.2e-104 347.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain Cytochrome_CBB3 PF13442.6 AAAP01003782.1_7 - 1.5e-12 47.6 0.1 3.3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003782.1_7 - 5.5e-06 27.4 1.1 0.0001 23.4 1.1 2.4 1 1 0 1 1 1 1 Cytochrome c PQQ_3 PF13570.6 AAAP01003782.1_7 - 0.0064 16.9 1.8 8.6 7.0 0.0 4.0 5 0 0 5 5 5 1 PQQ-like domain Lactonase PF10282.9 AAAP01003782.1_7 - 0.015 14.6 0.0 0.067 12.4 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 AAAP01003782.1_7 - 0.021 15.1 0.0 11 6.4 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 AAAP01003782.1_7 - 0.042 12.9 0.0 0.47 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Cytochrom_C550 PF14495.6 AAAP01003782.1_7 - 0.085 12.6 0.0 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c-550 domain SPASM PF13186.6 AAAP01003782.1_8 - 0.0028 18.1 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain PurS PF02700.14 AAAP01003783.1_3 - 2.7e-34 117.2 0.0 3e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase SAICAR_synt PF01259.18 AAAP01003783.1_4 - 3.1e-62 210.5 0.0 3.5e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase TANGO2 PF05742.12 AAAP01003783.1_5 - 2.6e-27 96.5 0.0 2.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 DUF1476 PF07345.11 AAAP01003783.1_6 - 5.9e-33 113.3 3.3 6.6e-33 113.1 3.3 1.0 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta GGDEF PF00990.21 AAAP01003783.1_7 - 1.1e-52 178.0 0.0 2.1e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003783.1_7 - 6.2e-21 74.6 0.0 1.8e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003783.1_7 - 9.6e-20 70.7 0.0 2.5e-13 50.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01003783.1_7 - 1.5e-11 44.0 0.1 8.1e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAAP01003783.1_7 - 7.9e-11 42.2 0.0 7.6e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.7 AAAP01003783.1_7 - 0.0057 16.8 0.0 2.7 8.2 0.0 3.3 2 2 0 2 2 2 1 PAS fold Spidroin_MaSp PF11260.8 AAAP01003783.1_7 - 0.14 12.5 0.4 0.34 11.2 0.4 1.6 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 MeaB PF03308.16 AAAP01003783.1_8 - 3.4e-69 232.8 3.4 4.3e-69 232.5 3.4 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 AAAP01003783.1_8 - 1.2e-06 28.5 0.0 0.00047 20.0 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 AAAP01003783.1_8 - 9e-06 25.5 0.2 9e-06 25.5 0.2 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003783.1_8 - 5.3e-05 23.2 0.0 0.0074 16.2 0.0 2.7 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003783.1_8 - 6.3e-05 23.0 0.0 0.00043 20.3 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 AAAP01003783.1_8 - 0.00032 21.2 0.0 0.02 15.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 AAAP01003783.1_8 - 0.0008 19.0 0.2 0.011 15.4 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AAAP01003783.1_8 - 0.001 19.4 0.6 0.12 12.6 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AAAP01003783.1_8 - 0.0012 19.3 0.4 0.0097 16.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 AAAP01003783.1_8 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.27 AAAP01003783.1_8 - 0.0016 19.0 0.0 0.0083 16.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 AAAP01003783.1_8 - 0.002 18.1 0.1 0.007 16.3 0.2 1.9 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 AAAP01003783.1_8 - 0.0036 17.0 0.0 0.0093 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AAAP01003783.1_8 - 0.0078 16.6 0.1 0.088 13.2 0.1 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003783.1_8 - 0.01 16.1 0.0 0.043 14.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAAP01003783.1_8 - 0.014 15.7 0.1 0.04 14.3 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 AAAP01003783.1_8 - 0.025 14.2 0.8 0.074 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AAAP01003783.1_8 - 0.035 14.3 0.4 0.13 12.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.27 AAAP01003783.1_8 - 0.037 13.6 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.6 AAAP01003783.1_8 - 0.045 14.1 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AAAP01003783.1_8 - 0.062 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 AAAP01003783.1_8 - 0.073 13.0 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 AAAP01003783.1_8 - 0.086 12.6 0.1 0.24 11.1 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 AAAP01003783.1_8 - 0.1 12.6 0.1 0.58 10.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 AAAP01003783.1_8 - 0.12 12.3 1.1 0.79 9.6 0.0 2.4 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 AAAP01003783.1_8 - 0.14 11.7 0.1 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B CbiA PF01656.23 AAAP01003783.1_8 - 0.18 11.9 0.0 0.34 11.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 AAAP01003783.1_8 - 0.24 11.9 0.0 0.4 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAAP01003783.1_8 - 0.25 11.4 0.0 0.97 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAAP01003783.1_8 - 0.47 9.7 2.2 0.71 9.1 0.0 2.2 3 0 0 3 3 2 0 Zeta toxin DsbB PF02600.16 AAAP01003783.1_9 - 1.2e-29 103.6 10.9 1.4e-29 103.4 10.9 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB LysE PF01810.18 AAAP01003783.1_9 - 0.23 10.9 5.7 0.12 11.9 3.6 1.6 2 1 0 2 2 2 0 LysE type translocator 7TMR-DISM_7TM PF07695.11 AAAP01003783.1_9 - 1.3 8.8 7.0 0.36 10.7 3.8 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling COQ7 PF03232.13 AAAP01003783.1_10 - 4.1e-72 241.5 0.1 4.6e-72 241.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 AAAP01003783.1_10 - 7.3e-10 39.4 0.0 9.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Rubrerythrin LcrG PF07216.12 AAAP01003783.1_10 - 0.052 13.5 0.1 0.15 12.0 0.1 1.8 1 1 1 2 2 2 0 LcrG protein AOX PF01786.17 AAAP01003783.1_10 - 0.062 12.9 0.6 0.18 11.4 0.2 1.8 1 1 1 2 2 2 0 Alternative oxidase His_Phos_1 PF00300.22 AAAP01003783.1_11 - 1.2e-38 132.7 0.0 1.5e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NUDIX PF00293.28 AAAP01003783.1_12 - 1.9e-08 34.4 0.0 3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Usp PF00582.26 AAAP01003783.1_13 - 4.9e-16 59.5 4.5 2.5e-08 34.5 0.2 3.3 3 1 0 3 3 3 3 Universal stress protein family AAA_33 PF13671.6 AAAP01003783.1_14 - 1.2e-10 41.7 0.0 1.6e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain TetR_C_6 PF13977.6 AAAP01003783.1_14 - 0.007 16.6 2.0 0.013 15.7 2.0 1.5 1 1 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal Zeta_toxin PF06414.12 AAAP01003783.1_14 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Transket_pyr PF02779.24 AAAP01003784.1_1 - 1.3e-46 158.5 0.0 4.2e-46 156.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.21 AAAP01003784.1_1 - 1.6e-32 112.8 0.2 2.8e-32 112.0 0.2 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AAAP01003784.1_1 - 8.1e-13 48.3 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain F_bP_aldolase PF01116.20 AAAP01003784.1_2 - 2.8e-94 315.7 0.1 3.7e-94 315.3 0.1 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AP_endonuc_2 PF01261.24 AAAP01003784.1_2 - 0.0025 17.3 0.0 0.0081 15.6 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribul_P_3_epim PF00834.19 AAAP01003784.1_3 - 2.7e-86 288.0 0.5 3.1e-86 287.8 0.5 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 AAAP01003784.1_3 - 0.00026 20.5 0.5 0.0052 16.3 0.2 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.17 AAAP01003784.1_3 - 0.0043 16.5 1.7 0.29 10.5 0.0 2.1 1 1 1 2 2 2 2 PcrB family TMP-TENI PF02581.17 AAAP01003784.1_3 - 0.0075 15.6 0.3 0.0075 15.6 0.3 1.4 2 0 0 2 2 2 1 Thiamine monophosphate synthase ADH_zinc_N PF00107.26 AAAP01003784.1_3 - 0.0078 16.2 0.1 0.49 10.4 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase QRPTase_C PF01729.19 AAAP01003784.1_3 - 0.022 14.5 0.6 0.15 11.8 0.1 2.3 1 1 2 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pyridox_ox_2 PF12900.7 AAAP01003784.1_4 - 1.5e-44 151.4 0.0 1.8e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_1_2 PF00155.21 AAAP01003784.1_5 - 4e-21 75.6 0.0 5.5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AAAP01003784.1_5 - 1.1e-11 44.2 0.2 1.1e-11 44.2 0.2 2.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family PBP_like_2 PF12849.7 AAAP01003784.1_6 - 3.9e-46 158.0 0.4 4.6e-46 157.8 0.4 1.0 1 0 0 1 1 1 1 PBP superfamily domain DUF3708 PF12501.8 AAAP01003784.1_7 - 8.8e-38 129.7 8.9 8.8e-38 129.7 8.9 2.3 2 1 0 2 2 2 1 Phosphate ATP-binding cassette transporter BPD_transp_1 PF00528.22 AAAP01003784.1_7 - 4.1e-15 56.0 18.6 4.1e-15 56.0 18.6 3.1 1 1 3 4 4 4 1 Binding-protein-dependent transport system inner membrane component 2TM PF13239.6 AAAP01003784.1_7 - 2 8.8 5.9 0.25 11.7 0.5 2.3 2 0 0 2 2 2 0 2TM domain DUF3333 PF11812.8 AAAP01003784.1_8 - 2.5e-48 164.2 2.3 2.9e-48 163.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3333) BPD_transp_1 PF00528.22 AAAP01003784.1_8 - 1.1e-19 70.9 12.4 1.1e-19 70.9 12.4 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01003784.1_9 - 1.6e-30 106.4 0.0 2.3e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003784.1_9 - 9.2e-12 45.4 0.0 7.8e-05 22.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003784.1_9 - 7.7e-08 32.0 0.1 4.1e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAAP01003784.1_9 - 0.0001 22.0 0.1 0.0011 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003784.1_9 - 0.00052 19.9 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 AAAP01003784.1_9 - 0.00057 19.7 0.0 0.0015 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003784.1_9 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003784.1_9 - 0.0012 19.4 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003784.1_9 - 0.0032 17.8 0.1 0.0064 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003784.1_9 - 0.0041 17.4 0.0 0.0083 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01003784.1_9 - 0.0089 15.8 0.2 0.43 10.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01003784.1_9 - 0.04 14.4 0.1 1.3 9.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AAAP01003784.1_9 - 0.052 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 AAAP01003784.1_9 - 0.074 12.8 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 AAAP01003784.1_9 - 0.094 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AAAP01003784.1_9 - 0.098 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003784.1_9 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAAP01003784.1_9 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 AAAP01003784.1_9 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PhoU PF01895.19 AAAP01003784.1_10 - 1.3e-41 140.9 5.3 3.9e-21 75.3 0.5 2.1 2 0 0 2 2 2 2 PhoU domain Response_reg PF00072.24 AAAP01003784.1_11 - 2.3e-32 111.5 0.0 2.6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain AsmA PF05170.14 AAAP01003785.1_1 - 5.7e-61 207.1 1.1 2.6e-30 105.8 0.0 2.1 2 0 0 2 2 2 2 AsmA family AsmA_2 PF13502.6 AAAP01003785.1_1 - 6.7e-26 91.2 10.0 3e-24 85.8 5.9 3.0 2 2 1 3 3 3 2 AsmA-like C-terminal region DUF190 PF02641.15 AAAP01003785.1_2 - 4.8e-35 119.8 0.0 5.4e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 Adenine_glyco PF03352.13 AAAP01003785.1_2 - 0.23 11.2 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase CRCB PF02537.15 AAAP01003785.1_3 - 6.6e-24 84.1 11.7 7.7e-24 83.8 11.7 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF3180 PF11377.8 AAAP01003785.1_3 - 0.025 14.7 3.8 0.025 14.7 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) GGDEF PF00990.21 AAAP01003785.1_4 - 1.1e-48 165.0 0.2 1.6e-48 164.5 0.2 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003785.1_4 - 4.3e-31 107.2 0.0 5.3e-16 58.8 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 AAAP01003785.1_4 - 7.7e-25 87.1 0.0 2.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01003785.1_4 - 4.1e-17 62.4 0.1 1.9e-10 40.9 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01003785.1_4 - 2.2e-14 53.0 0.2 2e-05 24.5 0.0 3.7 4 0 0 4 4 4 2 PAS domain PAS_3 PF08447.12 AAAP01003785.1_4 - 4.9e-11 42.8 0.5 2.5e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 PAS fold DAGK_cat PF00781.24 AAAP01003785.1_4 - 0.039 13.6 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain BPD_transp_1 PF00528.22 AAAP01003785.1_5 - 5.8e-23 81.6 9.4 7.4e-23 81.2 9.4 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AAAP01003785.1_6 - 4.6e-29 101.7 0.0 7.2e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AAAP01003785.1_6 - 1e-11 45.0 1.2 5.9e-10 39.3 0.7 2.8 3 0 0 3 3 3 1 TOBE domain AAA_21 PF13304.6 AAAP01003785.1_6 - 1.3e-07 31.8 0.9 0.0013 18.6 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003785.1_6 - 0.00046 19.7 0.1 0.54 9.7 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003785.1_6 - 0.0035 17.8 0.2 0.0061 17.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAAP01003785.1_6 - 0.0095 16.5 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003785.1_6 - 0.035 14.4 0.1 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003785.1_6 - 0.055 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 AAAP01003785.1_6 - 0.076 13.4 0.0 0.41 11.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 AAAP01003785.1_6 - 0.077 13.2 0.0 2.5 8.4 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AAAP01003785.1_6 - 0.078 12.7 0.7 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Response_reg PF00072.24 AAAP01003785.1_7 - 2.1e-28 98.7 0.0 2.5e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Prim_Zn_Ribbon PF08273.12 AAAP01003785.1_7 - 0.041 14.2 2.1 0.33 11.2 2.5 2.2 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase PhnA_Zn_Ribbon PF08274.12 AAAP01003785.1_7 - 0.082 12.9 0.5 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Cys_rich_CPCC PF14206.6 AAAP01003785.1_7 - 0.093 12.6 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Cysteine-rich CPCC Zn_Tnp_IS1595 PF12760.7 AAAP01003785.1_7 - 0.31 11.1 3.0 4.4 7.4 3.0 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAAP01003785.1_7 - 3.8 7.7 5.6 1.7 8.8 0.5 2.3 1 1 1 2 2 2 0 Zinc ribbon domain PADR1 PF08063.12 AAAP01003785.1_7 - 4.6 7.1 5.0 9.6 6.1 0.1 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain PikAIV_N PF18605.1 AAAP01003785.1_9 - 0.024 14.2 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NiFeSe_Hases PF00374.19 AAAP01003785.1_11 - 5e-34 118.1 0.0 1.2e-16 60.7 0.0 2.8 3 0 0 3 3 3 2 Nickel-dependent hydrogenase Oxidored_q6 PF01058.22 AAAP01003785.1_12 - 2.7e-30 104.9 0.1 3.2e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NADH-G_4Fe-4S_3 PF10588.9 AAAP01003785.1_13 - 1.5e-13 50.0 0.3 1.5e-13 50.0 0.3 2.1 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 AAAP01003785.1_13 - 3.1e-13 49.6 0.0 9.6e-13 48.0 0.0 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.6 AAAP01003785.1_13 - 1.1e-12 48.5 1.5 1.2e-11 45.2 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer2 PF00111.27 AAAP01003785.1_13 - 5.1e-11 42.4 0.4 1.7e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AAAP01003785.1_13 - 0.033 14.0 8.4 0.049 13.5 0.3 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 AAAP01003785.1_13 - 1 10.0 6.1 0.14 12.7 0.9 2.3 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I NADH_4Fe-4S PF10589.9 AAAP01003785.1_14 - 7.3e-26 90.1 0.0 1.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AAAP01003785.1_14 - 0.00029 20.6 0.0 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Cys_Met_Meta_PP PF01053.20 AAAP01003786.1_1 - 9.7e-111 370.0 0.0 1.2e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01003786.1_1 - 0.00018 21.0 0.1 0.00032 20.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAAP01003786.1_1 - 0.073 12.3 0.1 0.42 9.9 0.1 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase ECH_2 PF16113.5 AAAP01003786.1_2 - 1.3e-119 399.6 0.0 1.5e-119 399.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAAP01003786.1_2 - 5.5e-32 111.1 0.0 7.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MotB_plug PF13677.6 AAAP01003786.1_4 - 7e-20 70.4 0.7 1.1e-19 69.7 0.7 1.3 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AAAP01003786.1_4 - 3.1e-14 53.1 0.0 6.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 OmpA family ExbD PF02472.16 AAAP01003786.1_4 - 0.018 15.2 0.1 0.049 13.8 0.0 1.8 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 AAAP01003786.1_5 - 1.1e-19 70.4 0.6 2.2e-19 69.5 0.6 1.6 1 1 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ATP-grasp_5 PF13549.6 AAAP01003786.1_6 - 3.3e-91 304.7 0.9 4.8e-91 304.2 0.9 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AAAP01003786.1_6 - 3.2e-59 198.7 0.2 6.2e-59 197.7 0.2 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAAP01003786.1_6 - 1.9e-20 73.5 0.0 9.1e-20 71.3 0.0 2.3 1 0 0 1 1 1 1 CoA binding domain Acetyltransf_1 PF00583.25 AAAP01003786.1_6 - 9e-10 38.8 0.0 3.3e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAAP01003786.1_6 - 1.9e-07 31.8 0.0 5.2e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003786.1_6 - 0.00033 20.6 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATP-grasp_2 PF08442.10 AAAP01003786.1_6 - 0.012 15.2 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Acetyltransf_8 PF13523.6 AAAP01003786.1_6 - 0.016 14.9 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003786.1_6 - 0.043 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAAP01003786.1_6 - 0.05 13.7 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 AAAP01003786.1_6 - 0.07 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PTA_PTB PF01515.19 AAAP01003786.1_7 - 4.4e-53 180.7 3.4 1.9e-48 165.4 2.8 2.2 1 1 1 2 2 2 2 Phosphate acetyl/butaryl transferase MaoC_dehydratas PF01575.19 AAAP01003786.1_7 - 5.5e-13 48.6 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01003786.1_7 - 7.3e-05 22.9 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Acetate_kinase PF00871.17 AAAP01003786.1_8 - 2.1e-111 372.4 0.0 2.4e-111 372.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family NAD_binding_10 PF13460.6 AAAP01003786.1_8 - 0.083 12.8 0.1 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding HATPase_c PF02518.26 AAAP01003786.1_9 - 1.5e-19 70.5 0.0 5.2e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAAP01003786.1_9 - 0.04 13.7 0.0 0.097 12.4 0.0 1.6 1 1 0 1 1 1 0 Cache domain HATPase_c_3 PF13589.6 AAAP01003786.1_9 - 0.073 12.9 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003786.1_9 - 0.14 12.2 0.2 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAAP01003786.1_10 - 2.7e-19 69.4 0.0 3.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GST_N_3 PF13417.6 AAAP01003786.1_10 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cyclophil_like PF04126.13 AAAP01003786.1_11 - 8.1e-40 135.4 0.0 9.2e-40 135.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 AAAP01003786.1_11 - 2.1e-06 27.7 0.0 2.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin-like family cNMP_binding PF00027.29 AAAP01003786.1_13 - 4e-21 74.9 0.2 6.6e-21 74.2 0.1 1.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain TPP_enzyme_C PF02775.21 AAAP01003786.1_14 - 4.3e-39 133.8 0.1 5.1e-38 130.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAAP01003786.1_14 - 1.3e-28 99.5 0.0 2.5e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 AAAP01003786.1_14 - 0.00067 18.6 0.1 0.39 9.5 0.1 2.2 2 0 0 2 2 2 2 XFP N-terminal domain E1_dh PF00676.20 AAAP01003786.1_14 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component 4HB_MCP_1 PF12729.7 AAAP01003787.1_1 - 2.3e-26 92.4 0.2 2.3e-26 92.4 0.2 3.0 3 0 0 3 3 3 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003787.1_1 - 1.6e-06 28.4 0.3 5.1e-06 26.8 0.3 2.0 1 0 0 1 1 1 1 HAMP domain Mod_r PF07200.13 AAAP01003787.1_1 - 7.3 6.7 7.7 5.7 7.0 3.5 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BPD_transp_2 PF02653.16 AAAP01003787.1_2 - 1.5e-51 175.2 44.3 1.8e-51 174.9 44.3 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01003787.1_3 - 1.8e-49 168.3 27.2 1.8e-49 168.3 27.2 1.9 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 AAAP01003787.1_3 - 4.8e-11 42.8 8.0 4.8e-11 42.8 8.0 3.4 4 2 0 4 4 4 1 Domain of unknown function (DUF3382) ABC_tran PF00005.27 AAAP01003787.1_4 - 6.8e-27 94.7 0.0 9.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01003787.1_4 - 1.1e-09 38.0 0.3 2e-09 37.2 0.3 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AAAP01003787.1_4 - 3.8e-07 30.2 0.0 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003787.1_4 - 7.7e-06 26.6 0.4 1.2e-05 25.9 0.4 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAAP01003787.1_4 - 0.00021 20.9 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003787.1_4 - 0.00024 21.4 0.1 0.0073 16.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003787.1_4 - 0.00089 19.7 0.0 0.0016 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003787.1_4 - 0.00099 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AAAP01003787.1_4 - 0.0024 17.7 0.0 0.033 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AAAP01003787.1_4 - 0.0037 16.7 0.0 0.0077 15.7 0.0 1.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01003787.1_4 - 0.0052 16.7 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003787.1_4 - 0.03 14.4 0.0 0.069 13.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01003787.1_4 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_30 PF13604.6 AAAP01003787.1_4 - 0.067 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AAAP01003787.1_4 - 0.11 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAAP01003787.1_4 - 0.19 10.5 0.0 1.5 7.5 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF3584 PF12128.8 AAAP01003787.1_4 - 0.27 8.7 0.1 0.36 8.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC_tran PF00005.27 AAAP01003787.1_5 - 5.9e-30 104.6 0.0 7.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003787.1_5 - 1.4e-11 44.7 1.3 4.4e-06 26.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003787.1_5 - 0.0012 19.4 0.1 0.0017 18.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003787.1_5 - 0.003 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003787.1_5 - 0.0055 17.1 0.1 0.0098 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAAP01003787.1_5 - 0.0071 15.9 1.7 0.027 14.0 0.6 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003787.1_5 - 0.015 15.2 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 AAAP01003787.1_5 - 0.016 14.8 0.2 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 AAAP01003787.1_5 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01003787.1_5 - 0.022 14.2 0.7 0.73 9.2 0.2 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 AAAP01003787.1_5 - 0.035 14.0 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 AAAP01003787.1_5 - 0.036 13.8 0.4 0.099 12.3 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AAAP01003787.1_5 - 0.039 13.7 0.2 0.081 12.6 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 AAAP01003787.1_5 - 0.053 13.7 0.1 0.095 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01003787.1_5 - 0.093 12.3 0.3 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AAAP01003787.1_5 - 0.11 12.7 0.4 0.62 10.3 0.4 2.1 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AAAP01003787.1_5 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 AAAP01003787.1_5 - 0.13 9.8 0.2 0.16 9.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_14 PF13173.6 AAAP01003787.1_5 - 0.14 12.2 0.0 0.74 9.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAAP01003787.1_5 - 0.15 12.3 0.2 0.74 10.1 0.2 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit VirC1 PF07015.11 AAAP01003787.1_5 - 0.17 11.2 0.4 0.37 10.0 0.3 1.7 1 1 0 1 1 1 0 VirC1 protein NB-ARC PF00931.22 AAAP01003787.1_5 - 0.18 11.0 0.2 0.34 10.1 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 AAAP01003787.1_5 - 0.24 10.9 0.2 3.1 7.3 0.1 2.1 1 1 0 2 2 2 0 P-loop containing dynein motor region SBP_bac_3 PF00497.20 AAAP01003787.1_7 - 1.4e-32 113.0 0.0 1.9e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HATPase_c PF02518.26 AAAP01003787.1_7 - 2.1e-20 73.3 0.3 8.4e-20 71.4 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AAAP01003787.1_7 - 2e-10 40.4 0.0 5.3e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAAP01003787.1_7 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 AAAP01003787.1_7 - 2.9e-08 33.6 0.0 1.3e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003787.1_7 - 2.7e-07 30.8 0.2 7.2e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003787.1_7 - 1.5e-06 28.4 0.1 3.7e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003787.1_7 - 1.6e-06 28.1 0.1 3.6e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 PAS fold GGDEF PF00990.21 AAAP01003787.1_8 - 1.5e-40 138.6 0.0 5e-40 136.9 0.0 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAAP01003787.1_8 - 1.4e-15 57.5 0.1 2.8e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain GAF_2 PF13185.6 AAAP01003787.1_8 - 0.084 13.2 0.3 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 GAF domain LpoB PF13036.6 AAAP01003787.1_9 - 4.2e-19 68.9 0.0 5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Peptidoglycan-synthase activator LpoB TPR_16 PF13432.6 AAAP01003787.1_10 - 0.00024 21.7 4.1 0.00024 21.7 4.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003787.1_10 - 0.00039 20.3 7.7 0.0037 17.3 2.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003787.1_10 - 0.00056 19.6 3.2 0.0052 16.5 2.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003787.1_10 - 0.0057 16.9 1.7 0.57 10.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003787.1_10 - 0.013 16.1 4.6 0.06 14.0 1.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.13 AAAP01003787.1_10 - 0.018 15.1 0.6 0.066 13.3 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF357) TPR_17 PF13431.6 AAAP01003787.1_10 - 0.027 14.8 0.5 0.074 13.5 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003787.1_10 - 0.1 12.9 1.1 0.36 11.1 1.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003787.1_10 - 0.58 11.1 7.2 1.4 9.9 0.7 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003787.1_10 - 0.76 9.7 3.8 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1425 PF07233.12 AAAP01003787.1_11 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) LPAM_1 PF08139.12 AAAP01003787.1_11 - 0.14 12.7 1.2 0.26 11.9 0.7 1.7 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4189 PF13827.6 AAAP01003787.1_13 - 2.7e-17 63.1 11.0 3.4e-17 62.8 11.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4189) Semialdhyde_dh PF01118.24 AAAP01003787.1_14 - 1.6e-11 44.7 0.0 1.7e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAAP01003787.1_14 - 0.051 13.8 0.0 0.062 13.6 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 AAAP01003787.1_14 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Fumerase PF05681.14 AAAP01003788.1_1 - 2.7e-87 292.6 0.0 3.5e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 AAAP01003788.1_1 - 9.2e-28 97.0 0.0 1.8e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Fumarase C-terminus Histone_H2A_C PF16211.5 AAAP01003788.1_1 - 0.0042 16.8 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Colipase_C PF02740.14 AAAP01003788.1_1 - 0.069 13.3 0.7 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Colipase, C-terminal domain SspB PF04386.13 AAAP01003788.1_2 - 1.8e-48 164.4 0.0 2.1e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Stringent starvation protein B GGDEF PF00990.21 AAAP01003788.1_3 - 3.6e-32 111.4 0.0 5e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAAP01003788.1_3 - 0.0032 17.7 0.4 0.011 16.0 0.4 1.9 1 1 0 1 1 1 1 GGDEF-like domain ptaRNA1_toxin PF12703.7 AAAP01003788.1_4 - 0.18 11.8 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system Thymidylat_synt PF00303.19 AAAP01003788.1_5 - 7.5e-124 412.2 0.0 8.4e-124 412.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 AAAP01003788.1_6 - 1.5e-56 190.5 0.0 1.7e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase BPD_transp_1 PF00528.22 AAAP01003788.1_7 - 8.6e-21 74.5 40.0 7.3e-13 48.7 9.7 3.3 3 1 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component CoatB PF10389.9 AAAP01003788.1_7 - 0.00064 19.5 4.3 0.0029 17.4 1.5 2.8 2 0 0 2 2 2 1 Bacteriophage coat protein B AAA_assoc_C PF09821.9 AAAP01003788.1_8 - 3.6e-42 143.6 0.8 5.8e-42 143.0 0.8 1.3 1 0 0 1 1 1 1 C-terminal AAA-associated domain ABC_tran PF00005.27 AAAP01003788.1_8 - 2.4e-32 112.3 0.0 4.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003788.1_8 - 4.6e-07 30.0 0.5 0.0099 15.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AAAP01003788.1_8 - 0.00023 20.9 0.2 0.00058 19.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003788.1_8 - 0.00026 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AAAP01003788.1_8 - 0.0042 17.5 0.4 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003788.1_8 - 0.015 15.0 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003788.1_8 - 0.02 15.2 0.7 0.82 9.9 0.1 2.8 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 AAAP01003788.1_8 - 0.032 14.3 1.4 1.8 8.7 0.8 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 AAAP01003788.1_8 - 0.04 13.8 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 AAAP01003788.1_8 - 0.13 12.4 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 AAAP01003788.1_8 - 0.14 12.2 0.2 0.38 10.7 0.2 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 AAAP01003788.1_8 - 0.16 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAAP01003788.1_8 - 0.28 10.3 0.0 0.45 9.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF87 PF01935.17 AAAP01003788.1_8 - 0.71 9.9 2.4 0.69 10.0 1.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain DctP PF03480.13 AAAP01003788.1_9 - 1.3e-28 100.1 0.0 1.7e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 NDUF_B12 PF08122.12 AAAP01003788.1_9 - 0.025 14.6 2.8 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Methyltransf_11 PF08241.12 AAAP01003788.1_10 - 4.9e-11 43.1 0.0 9.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003788.1_10 - 1.9e-09 37.6 0.1 3.3e-09 36.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003788.1_10 - 3.1e-06 27.8 0.0 5.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003788.1_10 - 1.2e-05 25.2 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003788.1_10 - 1.2e-05 24.7 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AAAP01003788.1_10 - 1.7e-05 25.4 0.0 4.1e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 AAAP01003788.1_10 - 0.019 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Oxidored_FMN PF00724.20 AAAP01003788.1_11 - 1.5e-73 248.0 0.0 2.1e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 AAAP01003788.1_11 - 3e-25 89.1 0.0 7.8e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003788.1_11 - 1.1e-09 38.1 0.4 0.002 17.4 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003788.1_11 - 1.2e-09 38.3 0.3 3.6e-09 36.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAAP01003788.1_11 - 3.8e-08 32.5 0.5 7.8e-08 31.4 0.5 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 AAAP01003788.1_11 - 5.4e-08 33.3 0.5 0.00056 20.4 0.1 4.4 6 0 0 6 6 5 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003788.1_11 - 3e-07 30.3 9.7 1.2e-06 28.3 0.7 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAAP01003788.1_11 - 4.1e-07 29.7 2.5 6.5e-07 29.0 2.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003788.1_11 - 4.6e-07 29.3 1.7 9.2e-07 28.3 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAAP01003788.1_11 - 0.00015 20.9 0.7 0.00029 20.0 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAAP01003788.1_11 - 0.0059 15.7 0.5 0.012 14.7 0.5 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 AAAP01003788.1_11 - 0.018 15.0 1.1 0.24 11.4 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Dus PF01207.17 AAAP01003788.1_11 - 0.042 12.9 0.2 0.075 12.1 0.2 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) 3HCDH_N PF02737.18 AAAP01003788.1_11 - 0.063 13.2 1.6 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01003788.1_11 - 0.076 12.6 0.1 0.52 9.9 0.0 2.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 AAAP01003788.1_11 - 0.13 11.5 1.8 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 AAAP01003788.1_11 - 0.14 11.3 0.0 22 4.1 0.0 3.1 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 AAAP01003788.1_11 - 0.14 12.8 0.4 68 4.1 0.1 3.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AAAP01003788.1_11 - 0.17 11.2 4.1 0.12 11.6 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 AAAP01003788.1_11 - 0.26 10.9 1.6 19 4.9 0.0 3.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AAAP01003788.1_11 - 1.2 8.3 4.2 0.21 10.8 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 AAAP01003788.1_12 - 5.7e-61 206.4 0.0 6.9e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein ECH_1 PF00378.20 AAAP01003789.1_1 - 1.8e-28 99.6 0.0 2.1e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003789.1_1 - 8.3e-14 51.8 0.2 5.1e-12 45.9 0.0 2.0 1 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase HGD-D PF06050.13 AAAP01003789.1_2 - 1.9e-45 156.1 0.0 2.1e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component HGD-D PF06050.13 AAAP01003789.1_3 - 1.5e-47 163.0 0.0 1.8e-47 162.7 0.0 1.0 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component BcrAD_BadFG PF01869.20 AAAP01003789.1_4 - 5.7e-119 396.5 0.5 6.5e-119 396.3 0.5 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 AAAP01003789.1_4 - 0.009 15.6 0.3 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FtsA PF14450.6 AAAP01003789.1_4 - 0.27 11.7 1.7 0.47 10.9 0.1 2.2 2 1 1 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 AAAP01003789.1_5 - 4e-57 193.7 3.9 4.5e-57 193.6 3.9 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 AAAP01003789.1_5 - 0.019 15.4 4.6 2.3 8.7 4.6 2.8 1 1 0 1 1 1 0 Cell division protein FtsA Fer4 PF00037.27 AAAP01003789.1_6 - 1.9e-08 33.7 18.4 3.6e-07 29.7 2.2 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003789.1_6 - 7.4e-07 28.9 14.0 0.00094 19.1 4.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003789.1_6 - 1.3e-06 29.3 12.9 3.4e-05 24.7 4.9 2.1 1 1 1 2 2 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01003789.1_6 - 5.9e-06 26.8 15.0 2.4e-05 24.8 15.3 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003789.1_6 - 8.9e-06 25.8 29.6 0.00071 19.7 4.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003789.1_6 - 6.9e-05 22.9 15.8 0.00044 20.3 14.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003789.1_6 - 0.00019 21.3 19.5 0.0006 19.8 4.7 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003789.1_6 - 0.00084 19.7 2.8 0.00084 19.7 2.8 2.8 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003789.1_6 - 0.0028 17.7 18.1 0.038 14.1 18.2 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003789.1_6 - 0.023 15.2 2.1 0.023 15.2 2.1 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003789.1_6 - 0.057 14.4 5.8 0.057 14.4 5.8 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain GF_recep_IV PF14843.6 AAAP01003789.1_6 - 0.074 12.8 12.7 0.15 11.8 12.7 1.5 1 1 0 1 1 1 0 Growth factor receptor domain IV Fer4_17 PF13534.6 AAAP01003789.1_6 - 0.12 12.9 4.3 0.12 12.9 4.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAAP01003789.1_6 - 0.26 11.5 13.4 2.9 8.1 13.7 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyco_transf_41 PF13844.6 AAAP01003789.1_7 - 7e-90 301.7 0.0 1.8e-46 158.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 AAAP01003789.1_7 - 2e-34 114.9 22.4 1e-05 25.2 2.8 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003789.1_7 - 6.8e-30 101.7 13.6 2.9e-06 26.9 1.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003789.1_7 - 4.8e-28 96.6 7.9 2.6e-06 27.0 0.1 7.6 5 3 3 8 8 8 5 TPR repeat TPR_16 PF13432.6 AAAP01003789.1_7 - 5.1e-28 97.4 62.6 4.9e-09 36.7 1.3 6.5 2 1 3 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003789.1_7 - 1.9e-26 90.0 0.7 0.019 15.1 0.0 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003789.1_7 - 3.9e-23 80.1 2.3 0.0076 16.6 0.1 8.1 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003789.1_7 - 3.8e-22 78.6 22.1 1.3e-05 25.6 0.8 6.7 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003789.1_7 - 1.7e-21 75.1 46.0 2.1e-05 24.9 1.3 9.8 2 1 8 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003789.1_7 - 8.9e-19 67.6 32.9 8.1e-05 22.8 5.4 6.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003789.1_7 - 7.6e-13 47.5 24.0 0.012 15.5 0.0 8.5 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003789.1_7 - 8.4e-13 47.7 39.6 0.042 13.7 0.1 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003789.1_7 - 1.1e-07 32.0 1.3 0.0065 16.7 0.3 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AAAP01003789.1_7 - 3.3e-05 23.9 38.2 0.00021 21.4 1.9 5.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003789.1_7 - 0.0012 19.3 10.3 8 7.3 0.0 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003789.1_7 - 0.0018 18.7 49.4 0.0083 16.7 1.0 8.8 8 0 0 8 8 6 4 Tetratricopeptide repeat PknG_TPR PF16918.5 AAAP01003789.1_7 - 0.054 12.2 5.8 0.013 14.2 2.0 1.9 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat MAS20 PF02064.15 AAAP01003789.1_7 - 0.081 13.0 0.5 0.83 9.7 0.0 2.7 3 1 0 3 3 3 0 MAS20 protein import receptor Fis1_TPR_C PF14853.6 AAAP01003789.1_7 - 0.11 12.6 0.3 29 4.8 0.1 4.1 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 AAAP01003789.1_7 - 0.58 10.6 29.1 1.5 9.2 4.8 4.3 3 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 AAAP01003789.1_7 - 0.6 10.5 15.8 20 5.6 2.1 5.3 2 1 2 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 AAAP01003789.1_7 - 0.7 9.9 6.4 18 5.4 0.5 4.3 2 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) Methyltransf_11 PF08241.12 AAAP01003789.1_8 - 1.2e-21 77.1 0.1 1.9e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003789.1_8 - 9.8e-21 74.3 0.1 1.5e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003789.1_8 - 2.2e-17 63.4 0.0 2.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003789.1_8 - 6.2e-15 55.3 0.0 8.6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003789.1_8 - 2.5e-12 47.4 0.0 4.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01003789.1_8 - 6.1e-09 35.6 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAAP01003789.1_8 - 1.2e-08 34.6 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AAAP01003789.1_8 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 AAAP01003789.1_8 - 2.7e-06 27.4 0.1 1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 AAAP01003789.1_8 - 1.4e-05 24.7 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 AAAP01003789.1_8 - 0.00035 19.6 0.0 0.00047 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AAAP01003789.1_8 - 0.00042 20.3 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 AAAP01003789.1_8 - 0.0039 16.9 0.1 0.0082 15.8 0.0 1.5 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 AAAP01003789.1_8 - 0.004 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 AAAP01003789.1_8 - 0.0073 15.8 0.1 0.41 10.1 0.0 2.4 3 0 0 3 3 3 1 Putative methyltransferase DREV PF05219.12 AAAP01003789.1_8 - 0.016 14.3 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_2 PF00891.18 AAAP01003789.1_8 - 0.025 13.9 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 AAAP01003789.1_8 - 0.063 13.0 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) AdoMet_MTase PF07757.13 AAAP01003789.1_8 - 0.072 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.19 AAAP01003789.1_8 - 0.084 12.6 0.1 0.2 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 AAAP01003789.1_8 - 0.088 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF218 PF02698.17 AAAP01003789.1_9 - 1.4e-27 96.3 0.0 1.7e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 DUF218 domain CoA_transf_3 PF02515.17 AAAP01003789.1_10 - 1.5e-119 399.5 0.0 1.6e-119 399.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DPBB_1 PF03330.18 AAAP01003789.1_11 - 4.2e-26 91.0 0.0 5.7e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase HMGL-like PF00682.19 AAAP01003789.1_12 - 3e-44 151.6 0.0 6e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AAAP01003789.1_12 - 4.6e-28 97.8 0.1 1.1e-27 96.5 0.1 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain HEPN_Toprim_N PF18871.1 AAAP01003789.1_12 - 0.078 12.9 0.5 9 6.2 0.1 3.0 2 1 1 3 3 3 0 HEPN/Toprim N-terminal domain 1 SpoU_methylase PF00588.19 AAAP01003789.1_13 - 1.5e-27 96.5 0.0 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Ribosomal_S4 PF00163.19 AAAP01003789.1_14 - 1.1e-25 90.3 2.3 1.6e-25 89.8 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AAAP01003789.1_14 - 1.6e-18 66.1 0.1 5.3e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.6 AAAP01003789.1_14 - 0.028 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin Elong-fact-P_C PF09285.11 AAAP01003789.1_14 - 0.032 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P, C-terminal S4_2 PF13275.6 AAAP01003789.1_14 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain E1-E2_ATPase PF00122.20 AAAP01003789.1_14 - 0.13 11.7 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 E1-E2 ATPase Glutaredoxin PF00462.24 AAAP01003789.1_16 - 2.2e-19 69.4 0.0 3.8e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin BolA PF01722.18 AAAP01003789.1_17 - 2.4e-11 43.8 0.0 2.5e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein OprB PF04966.12 AAAP01003790.1_2 - 5e-70 236.8 6.7 6.4e-70 236.5 6.7 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family ETC_C1_NDUFA4 PF04800.12 AAAP01003790.1_3 - 3.7e-33 113.6 0.2 4.1e-33 113.5 0.2 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region PilZ PF07238.14 AAAP01003790.1_4 - 0.0021 18.3 0.0 0.0025 18.1 0.0 1.1 1 0 0 1 1 1 1 PilZ domain Abhydrolase_1 PF00561.20 AAAP01003790.1_5 - 2.9e-22 79.6 0.2 3.4e-16 59.7 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003790.1_5 - 8e-22 78.9 7.9 9.5e-22 78.7 7.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01003790.1_5 - 6.3e-08 32.2 0.1 3.8e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 AAAP01003790.1_5 - 8.3e-05 22.4 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 AAAP01003790.1_5 - 0.00011 22.1 0.1 0.015 15.0 0.1 2.3 1 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 AAAP01003790.1_5 - 0.0012 19.0 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.11 AAAP01003790.1_5 - 0.011 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 AAAP01003790.1_5 - 0.014 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 AAAP01003790.1_5 - 0.017 15.0 0.1 0.079 12.8 0.0 2.0 2 1 0 2 2 2 0 Serine hydrolase Ndr PF03096.14 AAAP01003790.1_5 - 0.16 10.6 0.0 0.55 8.9 0.0 1.7 2 0 0 2 2 2 0 Ndr family Abhydro_lipase PF04083.16 AAAP01003790.1_5 - 0.2 11.3 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region HD PF01966.22 AAAP01003790.1_6 - 4.1e-21 75.4 0.0 8.8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01003790.1_6 - 6.6e-19 67.9 0.0 2e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAAP01003790.1_6 - 0.029 13.9 0.2 0.15 11.5 0.2 2.1 1 1 0 1 1 1 0 HDOD domain Cytochrom_D1 PF02239.16 AAAP01003790.1_7 - 2.1e-152 506.9 2.6 2.5e-152 506.7 2.6 1.0 1 0 0 1 1 1 1 Cytochrome D1 heme domain Cytochrome_CBB3 PF13442.6 AAAP01003790.1_7 - 1.5e-11 44.4 0.0 3.9e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003790.1_7 - 0.00018 22.6 0.9 0.0041 18.2 0.9 2.6 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 AAAP01003790.1_7 - 0.0024 17.6 0.1 0.69 9.6 0.0 2.5 1 1 1 2 2 2 2 Cytochrome c-550 domain PQQ_3 PF13570.6 AAAP01003790.1_7 - 0.065 13.7 0.0 0.27 11.8 0.0 2.0 1 0 0 1 1 1 0 PQQ-like domain cNMP_binding PF00027.29 AAAP01003790.1_8 - 2e-17 63.0 0.0 3.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003790.1_8 - 2.5e-16 59.4 0.7 5.9e-16 58.2 0.7 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003790.1_8 - 0.13 12.0 0.8 0.3 10.8 0.8 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_Crp_2 PF13545.6 AAAP01003790.1_9 - 7.2e-16 57.9 0.3 1.4e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003790.1_9 - 4.6e-12 45.9 0.0 8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MarR_2 PF12802.7 AAAP01003790.1_9 - 0.00039 20.2 0.2 0.0011 18.8 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 AAAP01003790.1_9 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 AAAP01003790.1_9 - 0.004 17.1 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAAP01003790.1_9 - 0.0062 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 AAAP01003790.1_9 - 0.0081 16.5 0.1 0.13 12.6 0.0 2.2 1 1 1 2 2 2 1 Transcriptional regulator HTH_36 PF13730.6 AAAP01003790.1_9 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 AAAP01003790.1_9 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_AraC PF00165.23 AAAP01003790.1_9 - 0.087 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Cytochrom_NNT PF03264.14 AAAP01003790.1_10 - 2.4e-71 239.0 12.1 1.3e-70 236.6 8.4 2.3 2 0 0 2 2 2 1 NapC/NirT cytochrome c family, N-terminal region EB_dh PF09459.10 AAAP01003790.1_10 - 1.6e-49 169.2 5.3 3.4e-48 164.8 0.3 2.8 2 2 0 2 2 2 1 Ethylbenzene dehydrogenase Cytochrome_C7 PF14522.6 AAAP01003790.1_10 - 5.5e-07 29.5 22.0 0.0011 18.9 5.7 4.5 4 1 0 4 4 4 3 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 AAAP01003790.1_10 - 2.8e-05 24.5 20.5 0.089 13.3 7.5 4.1 4 0 0 4 4 4 2 Cytochrome c3 Cytochrom_CIII PF02085.16 AAAP01003790.1_10 - 0.003 17.9 22.1 0.17 12.3 1.2 3.8 4 0 0 4 4 4 2 Class III cytochrome C family Paired_CXXCH_1 PF09699.10 AAAP01003790.1_10 - 0.014 15.2 22.9 1.4 8.7 3.9 5.3 4 2 3 7 7 7 0 Doubled CXXCH motif (Paired_CXXCH_1) Neuropep_like PF15161.6 AAAP01003790.1_10 - 0.022 14.4 1.0 0.022 14.4 1.0 3.6 4 1 1 5 5 5 0 Neuropeptide-like GF_recep_IV PF14843.6 AAAP01003790.1_10 - 2.8 7.8 11.9 0.46 10.3 1.2 3.2 3 0 0 3 3 3 0 Growth factor receptor domain IV Cupredoxin_1 PF13473.6 AAAP01003790.1_11 - 1.1e-11 44.8 0.0 1.2e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 AAAP01003790.1_11 - 6.1e-10 39.4 0.0 4e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cytochrome_CBB3 PF13442.6 AAAP01003790.1_12 - 6.7e-12 45.6 0.0 8.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003790.1_12 - 4.4e-06 27.7 0.2 0.00011 23.3 0.2 2.1 1 1 0 1 1 1 1 Cytochrome c Cytochrom_D1 PF02239.16 AAAP01003790.1_13 - 8.3e-102 340.4 0.0 9.6e-102 340.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome D1 heme domain Lactonase PF10282.9 AAAP01003790.1_13 - 8.5e-05 22.0 0.0 0.037 13.3 0.0 2.8 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller AsnC_trans_reg2 PF17805.1 AAAP01003790.1_14 - 2.3e-21 75.7 0.0 3.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAAP01003790.1_14 - 2.3e-11 43.3 1.0 4.9e-11 42.3 0.1 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg2 PF17805.1 AAAP01003790.1_15 - 1.1e-24 86.3 0.0 6.2e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAAP01003790.1_15 - 3.2e-06 26.9 0.1 5.7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAAP01003790.1_15 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AsnC_trans_reg2 PF17805.1 AAAP01003790.1_16 - 1.6e-18 66.6 0.0 2.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAAP01003790.1_16 - 3.2e-08 33.3 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AAAP01003790.1_16 - 0.0062 16.1 0.4 0.036 13.6 0.4 2.0 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg2 PF17805.1 AAAP01003790.1_17 - 7.3e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AAAP01003790.1_17 - 4.6e-10 39.2 0.2 9.9e-10 38.1 0.2 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01003790.1_17 - 8.2e-05 21.9 0.0 0.00039 19.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 AAAP01003790.1_17 - 0.013 15.1 0.0 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAAP01003790.1_17 - 0.035 13.6 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Fer4_12 PF13353.6 AAAP01003790.1_18 - 0.0032 17.7 0.0 0.0037 17.5 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003790.1_18 - 0.008 16.3 0.0 0.009 16.1 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AAAP01003790.1_18 - 0.061 13.7 0.0 0.07 13.5 0.0 1.1 1 0 0 1 1 1 0 Radical SAM superfamily HAMP PF00672.25 AAAP01003791.1_1 - 8e-12 45.4 0.6 6.7e-11 42.4 0.5 2.4 2 0 0 2 2 2 1 HAMP domain HD_2 PF12917.7 AAAP01003791.1_1 - 0.05 13.3 0.4 0.075 12.8 0.4 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF349 PF03993.12 AAAP01003791.1_1 - 5.3 7.4 6.9 33 4.9 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PA PF02225.22 AAAP01003791.1_2 - 0.054 13.5 0.5 0.068 13.2 0.5 1.2 1 0 0 1 1 1 0 PA domain PBP_like_2 PF12849.7 AAAP01003791.1_3 - 2.3e-15 57.0 0.0 2.8e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AAAP01003791.1_3 - 9.6e-06 24.8 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AAAP01003791.1_3 - 8.8e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AAAP01003791.1_3 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 LysR substrate binding domain SBP_bac_1 PF01547.25 AAAP01003791.1_3 - 0.012 15.6 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein Mob_synth_C PF06463.13 AAAP01003791.1_4 - 3.3e-32 111.1 0.0 4.9e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAAP01003791.1_4 - 1.2e-29 103.9 0.1 1.7e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01003791.1_4 - 1.4e-08 35.1 0.0 2.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003791.1_4 - 1.2e-06 28.6 0.5 2.5e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain NrfD PF03916.14 AAAP01003791.1_6 - 2.1e-24 86.8 28.5 4.3e-24 85.7 28.5 1.4 1 1 0 1 1 1 1 Polysulphide reductase, NrfD DUF3087 PF11286.8 AAAP01003791.1_6 - 1.5 8.2 8.8 2.2 7.7 0.1 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3087) CbtB PF09489.10 AAAP01003791.1_6 - 1.9 8.6 4.3 5.3 7.2 0.0 3.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Fer4_11 PF13247.6 AAAP01003791.1_7 - 1.4e-16 60.4 14.7 2e-13 50.3 4.0 4.0 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003791.1_7 - 3.8e-15 56.2 23.8 6.6e-07 29.8 10.1 3.7 3 2 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003791.1_7 - 1.6e-11 44.1 22.5 4.7e-05 23.4 3.8 3.9 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003791.1_7 - 3.1e-11 42.6 12.4 6e-08 32.2 2.6 4.8 6 0 0 6 6 5 3 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003791.1_7 - 4.2e-10 39.6 21.0 0.00011 22.3 9.4 3.2 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003791.1_7 - 2.1e-08 33.7 9.8 4.1e-05 23.4 2.1 4.1 5 0 0 5 5 3 3 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003791.1_7 - 8.8e-08 32.6 14.0 0.0013 19.2 1.9 3.7 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003791.1_7 - 1.2e-07 32.1 31.7 0.061 14.3 5.4 4.4 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003791.1_7 - 3.9e-06 26.7 11.3 3.9e-05 23.5 1.8 4.3 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_15 PF13459.6 AAAP01003791.1_7 - 2.7e-05 24.8 9.5 0.01 16.6 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_8 PF13183.6 AAAP01003791.1_7 - 6.9e-05 23.2 28.2 0.0023 18.4 2.6 4.0 3 2 1 4 4 4 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003791.1_7 - 0.00012 22.3 31.3 0.0041 17.5 2.6 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003791.1_7 - 0.00035 20.6 25.8 0.01 16.0 9.9 3.5 3 2 1 4 4 4 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003791.1_7 - 0.0013 19.6 21.8 0.71 10.9 3.8 3.7 3 1 0 3 3 3 3 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 AAAP01003791.1_7 - 0.086 13.4 0.6 0.086 13.4 0.6 3.8 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AAAP01003791.1_7 - 0.57 11.1 19.5 3.4 8.6 1.9 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAAP01003791.1_7 - 3.8 7.7 17.9 1.8 8.8 7.7 3.4 3 1 1 4 4 4 0 4Fe-4S dicluster domain Molybdopterin PF00384.22 AAAP01003791.1_8 - 2.5e-29 102.5 0.0 3.5e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003791.1_8 - 1.7e-18 66.6 0.0 3.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003791.1_8 - 3.1e-14 52.7 0.9 5.6e-14 51.9 0.9 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AAAP01003791.1_8 - 0.00059 19.6 4.5 0.0019 18.0 4.5 1.9 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence AFOR_C PF01314.18 AAAP01003791.1_8 - 0.024 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 UCR_Fe-S_N PF10399.9 AAAP01003791.1_8 - 0.043 13.2 3.6 0.14 11.5 3.6 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_7 PF12838.7 AAAP01003791.1_9 - 7.6e-13 48.8 31.7 1.9e-06 28.4 8.6 4.5 3 2 2 5 5 5 5 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003791.1_9 - 2.5e-12 47.5 25.3 0.00044 21.1 1.8 4.7 4 1 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4 PF00037.27 AAAP01003791.1_9 - 7.8e-12 44.5 48.1 7.5e-07 28.7 5.5 5.7 6 0 0 6 6 6 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003791.1_9 - 4.1e-09 36.4 25.7 3e-05 24.1 4.0 3.5 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003791.1_9 - 4.7e-09 36.3 30.7 0.00026 21.1 7.9 4.1 3 1 2 5 5 5 4 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003791.1_9 - 1.5e-08 34.4 20.6 8.8e-06 25.6 1.2 6.1 7 0 0 7 7 7 3 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003791.1_9 - 2.6e-06 27.4 35.4 0.00026 21.0 10.1 4.6 3 2 3 6 6 6 5 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003791.1_9 - 9.9e-06 25.4 15.7 8.4e-05 22.4 2.3 6.2 7 0 0 7 7 7 3 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003791.1_9 - 5.5e-05 23.5 34.7 0.016 15.6 4.9 4.8 4 1 2 6 6 5 4 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003791.1_9 - 9.6e-05 22.6 13.0 0.0021 18.4 1.7 6.1 7 0 0 7 7 6 2 4Fe-4S binding domain Fer4_13 PF13370.6 AAAP01003791.1_9 - 0.036 14.6 1.1 0.036 14.6 1.1 4.6 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I DZR PF12773.7 AAAP01003791.1_9 - 0.056 13.5 0.2 0.056 13.5 0.2 3.8 4 1 0 4 4 3 0 Double zinc ribbon Fer4_17 PF13534.6 AAAP01003791.1_9 - 0.12 13.0 35.1 0.094 13.3 1.6 5.3 2 2 4 6 6 6 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAAP01003791.1_9 - 2.7 8.8 22.1 0.89 10.3 0.2 4.8 4 0 0 4 4 4 0 4Fe-4S single cluster domain Phosphonate-bd PF12974.7 AAAP01003791.1_10 - 5e-56 190.0 0.0 6.1e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAAP01003791.1_10 - 4.1e-11 42.7 0.0 3.2e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AAAP01003791.1_10 - 0.00083 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like HATPase_c PF02518.26 AAAP01003791.1_11 - 3.1e-22 79.2 0.0 5.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003791.1_11 - 1.1e-13 51.0 0.0 3.5e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003791.1_11 - 6e-12 45.8 0.7 5.7e-11 42.6 0.3 2.9 3 0 0 3 3 3 1 HAMP domain sCache_3_2 PF17203.4 AAAP01003791.1_11 - 7e-07 29.5 0.3 1.8e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 Single cache domain 3 HATPase_c_3 PF13589.6 AAAP01003791.1_11 - 0.0018 18.1 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AAAP01003791.1_11 - 0.0034 17.2 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain CHASE8 PF17152.4 AAAP01003791.1_11 - 0.015 15.6 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 Periplasmic sensor domain Sigma54_activat PF00158.26 AAAP01003791.1_12 - 7.8e-22 77.8 0.0 2.6e-19 69.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAAP01003791.1_12 - 3.3e-21 75.5 0.0 5.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAAP01003791.1_12 - 1.5e-14 54.3 0.0 2.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 AAAP01003791.1_12 - 3.4e-05 24.3 0.0 5.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 AAAP01003791.1_12 - 0.0052 16.8 0.0 0.35 10.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01003791.1_12 - 0.015 15.8 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAAP01003791.1_12 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 AAAP01003792.1_2 - 1.4e-09 38.9 6.5 1.7e-09 38.6 6.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003792.1_2 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01003792.1_2 - 0.023 14.0 0.0 0.36 10.0 0.0 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 AAAP01003792.1_3 - 3.1e-14 53.5 0.0 5.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003792.1_3 - 1.2e-13 51.3 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003792.1_3 - 2.8e-13 50.5 0.0 4.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003792.1_3 - 9.3e-13 48.7 0.0 1.4e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003792.1_3 - 9.5e-13 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003792.1_3 - 6.6e-05 22.4 0.0 0.00016 21.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AAAP01003792.1_3 - 8.1e-05 22.3 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AAAP01003792.1_3 - 0.0045 17.0 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAAP01003792.1_3 - 0.0074 15.7 0.0 0.0096 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01003792.1_3 - 0.0088 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 AAAP01003792.1_3 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 AAAP01003792.1_3 - 0.034 13.9 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 AAAP01003792.1_3 - 0.042 13.1 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 AAAP01003792.1_3 - 0.045 12.9 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase CheR PF01739.18 AAAP01003792.1_3 - 0.18 11.2 0.0 0.53 9.7 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain AAA_26 PF13500.6 AAAP01003792.1_4 - 3.2e-56 190.3 0.0 3.5e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain P22_Cro PF14549.6 AAAP01003792.1_4 - 0.015 15.2 0.4 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro CbiA PF01656.23 AAAP01003792.1_4 - 0.041 14.0 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_3 PF00202.21 AAAP01003792.1_5 - 7.5e-105 350.9 0.0 9e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III AstE_AspA PF04952.14 AAAP01003792.1_5 - 0.027 13.6 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family HlyD_D23 PF16576.5 AAAP01003792.1_6 - 3.6e-24 85.2 0.6 6.2e-24 84.4 0.6 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003792.1_6 - 7.6e-19 68.4 1.1 9.8e-15 55.2 0.1 2.9 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01003792.1_6 - 1.1e-10 41.2 0.1 1e-09 38.1 0.0 2.6 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.20 AAAP01003792.1_6 - 1.7e-06 27.8 2.3 2.4e-06 27.3 0.2 2.2 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAAP01003792.1_6 - 0.00015 21.5 0.0 0.0012 18.6 0.0 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme DUF4131 PF13567.6 AAAP01003792.1_6 - 0.0017 18.0 2.8 1.7 8.3 0.1 3.4 3 1 0 3 3 3 2 Domain of unknown function (DUF4131) Peptidase_M23 PF01551.22 AAAP01003792.1_6 - 0.0054 16.9 0.0 8.2 6.7 0.0 3.5 3 1 0 3 3 3 2 Peptidase family M23 MacB_PCD PF12704.7 AAAP01003792.1_7 - 6.5e-14 52.7 1.1 9.9e-14 52.1 1.1 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 AAAP01003792.1_7 - 2.9e-09 37.3 0.4 2.9e-09 37.3 0.4 2.8 3 0 0 3 3 3 1 FtsX-like permease family Yip1 PF04893.17 AAAP01003792.1_7 - 1.2 8.9 5.9 0.47 10.2 1.6 2.1 2 0 0 2 2 2 0 Yip1 domain ABC_tran PF00005.27 AAAP01003792.1_8 - 2.2e-30 106.0 0.0 3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003792.1_8 - 4.7e-09 36.5 0.5 0.0017 18.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003792.1_8 - 1.3e-08 34.6 0.0 1.2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 AAAP01003792.1_8 - 0.00036 20.2 0.2 0.058 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003792.1_8 - 0.00044 20.7 5.6 0.0027 18.1 5.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003792.1_8 - 0.00069 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01003792.1_8 - 0.0023 18.2 0.5 0.11 12.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 AAAP01003792.1_8 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 AAAP01003792.1_8 - 0.038 13.7 0.0 0.77 9.5 0.0 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 AAAP01003792.1_8 - 0.049 14.2 0.6 0.37 11.4 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003792.1_8 - 0.05 13.3 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003792.1_8 - 0.1 12.7 2.6 0.75 10.0 2.6 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003792.1_8 - 0.11 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAAP01003792.1_8 - 0.19 12.2 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 AAAP01003792.1_8 - 0.2 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_15 PF13175.6 AAAP01003792.1_8 - 0.32 10.6 0.0 5.1 6.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Response_reg PF00072.24 AAAP01003792.1_9 - 2.8e-21 75.8 0.0 4.6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003792.1_9 - 2.2e-18 65.5 0.1 3.5e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003792.1_9 - 3.1e-06 26.8 0.3 1.4e-05 24.6 0.2 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003792.1_9 - 0.0082 15.6 0.2 0.027 14.0 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 MarR_2 PF12802.7 AAAP01003792.1_9 - 0.0098 15.8 1.3 0.1 12.5 0.0 2.9 2 1 1 3 3 3 1 MarR family HTH_40 PF14493.6 AAAP01003792.1_9 - 0.011 16.2 0.1 0.021 15.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AAAP01003792.1_9 - 0.023 14.7 0.1 0.066 13.3 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003792.1_9 - 0.068 13.0 0.1 0.27 11.1 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain DUF3798 PF12683.7 AAAP01003792.1_9 - 0.092 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) MobB PF03205.14 AAAP01003792.1_10 - 2.6e-33 114.7 0.0 3.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 AAAP01003792.1_10 - 0.00047 19.8 1.5 0.045 13.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 AAAP01003792.1_10 - 0.0019 18.1 0.1 0.11 12.5 0.3 2.3 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 AAAP01003792.1_10 - 0.0023 17.0 0.2 0.0035 16.4 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 AAAP01003792.1_10 - 0.0056 16.7 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AAAP01003792.1_10 - 0.0071 15.9 0.3 0.0092 15.6 0.3 1.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AAAP01003792.1_10 - 0.0078 16.7 0.0 0.01 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003792.1_10 - 0.04 14.2 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 AAAP01003792.1_10 - 0.063 13.0 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 AAAP01003792.1_10 - 0.079 13.1 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAAP01003792.1_10 - 0.084 12.6 0.2 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003792.1_10 - 0.093 13.1 0.0 0.28 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 AAAP01003792.1_10 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 AAAP01003792.1_10 - 0.12 12.9 0.3 0.18 12.3 0.1 1.5 2 0 0 2 2 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 AAAP01003792.1_10 - 0.24 10.7 0.4 0.39 10.0 0.4 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCPsignal PF00015.21 AAAP01003792.1_11 - 2.4e-28 99.1 16.7 2.4e-28 99.1 16.7 3.3 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003792.1_11 - 4.9e-10 39.6 0.2 4.9e-10 39.6 0.2 5.2 5 1 0 5 5 5 1 HAMP domain DUF1664 PF07889.12 AAAP01003792.1_11 - 0.0017 18.4 1.3 51 3.9 0.0 5.0 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) DUF3150 PF11348.8 AAAP01003792.1_11 - 0.028 13.6 0.3 0.084 12.1 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3150) DUF948 PF06103.11 AAAP01003792.1_11 - 0.059 13.6 9.8 0.37 11.1 0.1 5.0 5 2 0 5 5 5 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 AAAP01003792.1_11 - 0.16 11.2 6.2 0.11 11.7 4.2 1.7 1 1 0 1 1 1 0 Invariant surface glycoprotein Lactamase_B PF00753.27 AAAP01003792.1_12 - 1.5e-12 47.9 0.7 3e-12 47.0 0.7 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 AAAP01003792.1_12 - 6.9e-12 45.1 0.4 1.2e-09 37.9 0.2 2.8 2 1 0 2 2 2 2 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 AAAP01003792.1_12 - 1.2e-10 41.3 0.3 2.1e-09 37.2 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Pan_kinase PF03309.14 AAAP01003792.1_13 - 4.5e-72 242.2 0.0 7.7e-72 241.5 0.0 1.3 2 0 0 2 2 2 1 Type III pantothenate kinase BPL_LplA_LipB PF03099.19 AAAP01003792.1_14 - 5.2e-18 65.2 0.0 7.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB_2 PF16917.5 AAAP01003792.1_14 - 9.6e-15 54.6 0.2 1.7e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 AAAP01003792.1_14 - 1.6e-05 24.7 0.7 3.7e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF4444 PF14563.6 AAAP01003792.1_14 - 0.0023 17.6 0.3 0.005 16.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4444) Proton_antipo_M PF00361.20 AAAP01003792.1_15 - 5.2e-86 288.5 21.6 5.2e-86 288.5 21.6 1.9 2 0 0 2 2 2 1 Proton-conducting membrane transporter DUF751 PF05421.11 AAAP01003792.1_15 - 0.88 10.3 12.2 3.6 8.4 0.2 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF751) Transpeptidase PF00905.22 AAAP01003793.1_1 - 4.7e-21 75.3 0.1 5.3e-20 71.8 0.1 1.9 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain BacA PF02673.18 AAAP01003793.1_2 - 1.7e-49 168.9 16.6 2e-49 168.6 16.6 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA Fer4_20 PF14691.6 AAAP01003793.1_3 - 1.2e-34 118.4 1.5 1.9e-34 117.8 1.5 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AAAP01003793.1_3 - 2.1e-31 109.3 1.4 2.8e-31 108.9 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003793.1_3 - 1.9e-13 50.8 1.3 9e-06 26.2 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003793.1_3 - 7.6e-11 41.8 0.1 0.0001 21.7 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003793.1_3 - 2.3e-10 40.6 1.0 6.2e-10 39.2 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AAAP01003793.1_3 - 1.1e-06 29.1 2.4 0.011 16.2 0.3 3.1 2 2 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 AAAP01003793.1_3 - 1.4e-06 27.3 0.6 1.1e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 AAAP01003793.1_3 - 3.8e-06 26.7 2.2 0.00082 19.0 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AAAP01003793.1_3 - 1.5e-05 24.6 0.3 1.5e-05 24.6 0.3 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AAAP01003793.1_3 - 2.2e-05 23.9 0.2 4.9e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 AAAP01003793.1_3 - 4.3e-05 22.9 4.1 0.003 16.9 0.6 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 AAAP01003793.1_3 - 5.9e-05 22.5 1.0 0.00025 20.5 0.1 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AAAP01003793.1_3 - 0.00032 19.9 2.1 0.00075 18.7 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 AAAP01003793.1_3 - 0.0017 17.7 1.9 0.002 17.4 0.3 1.9 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 AAAP01003793.1_3 - 0.0041 16.5 0.8 0.044 13.2 0.2 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 AAAP01003793.1_3 - 0.005 16.9 0.3 0.023 14.7 0.3 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 AAAP01003793.1_3 - 0.011 15.7 0.1 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAAP01003793.1_3 - 0.014 16.0 1.8 0.69 10.5 0.1 3.4 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 AAAP01003793.1_3 - 0.018 14.2 0.1 0.078 12.1 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_2 PF03446.15 AAAP01003793.1_3 - 0.019 15.2 0.1 0.082 13.1 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 AAAP01003793.1_3 - 0.029 13.5 0.2 0.029 13.5 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A YjeF_N PF03853.15 AAAP01003793.1_3 - 0.042 13.7 0.3 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus zf-HIT PF04438.16 AAAP01003793.1_3 - 0.043 13.7 1.8 0.096 12.6 1.8 1.5 1 0 0 1 1 1 0 HIT zinc finger FMO-like PF00743.19 AAAP01003793.1_3 - 0.046 12.1 0.0 5.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 AAAP01003793.1_3 - 0.082 12.8 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AAAP01003793.1_3 - 0.12 12.3 0.7 0.59 10.0 0.2 2.4 3 0 0 3 3 3 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 AAAP01003793.1_3 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_2 PF00310.21 AAAP01003793.1_4 - 2.8e-153 510.6 0.0 3.7e-153 510.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 AAAP01003793.1_4 - 3e-152 507.0 0.0 5e-152 506.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AAAP01003793.1_4 - 9.1e-99 330.4 0.0 2.1e-98 329.3 0.0 1.6 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 AAAP01003793.1_4 - 3.8e-78 261.5 3.2 6.7e-78 260.6 3.2 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 AAAP01003793.1_4 - 0.00011 21.4 2.1 0.00028 20.0 1.4 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Hemerythrin PF01814.23 AAAP01003793.1_5 - 8.2e-05 23.2 0.1 0.28 11.8 0.0 2.0 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain SAPI PF16560.5 AAAP01003793.1_5 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative mobile pathogenicity island tRNA-synt_1b PF00579.25 AAAP01003793.1_6 - 3.8e-78 262.8 0.0 4.3e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MASE2 PF05230.11 AAAP01003793.1_7 - 0.16 12.1 3.2 0.26 11.4 1.9 2.1 2 1 1 3 3 3 0 MASE2 domain HIG_1_N PF04588.13 AAAP01003794.1_1 - 4.3 7.6 8.3 5.5 7.3 0.7 2.0 2 0 0 2 2 2 0 Hypoxia induced protein conserved region Cys_Met_Meta_PP PF01053.20 AAAP01003794.1_2 - 2e-98 329.4 0.0 2.3e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAAP01003794.1_2 - 1e-05 24.7 0.0 1.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAAP01003794.1_2 - 0.00056 19.2 0.0 0.0008 18.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAAP01003794.1_2 - 0.003 16.9 0.1 0.006 15.9 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1007 PF06226.13 AAAP01003794.1_3 - 7.4e-41 140.4 0.0 8.9e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1007) PIN_3 PF13470.6 AAAP01003794.1_3 - 0.024 15.4 0.1 0.036 14.8 0.1 1.2 1 0 0 1 1 1 0 PIN domain EF-hand_1 PF00036.32 AAAP01003794.1_3 - 0.033 13.7 0.2 0.1 12.2 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 AAAP01003794.1_3 - 0.12 12.4 0.1 0.37 10.8 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain NicO PF03824.16 AAAP01003794.1_4 - 2.3e-18 66.5 4.9 3.2e-18 66.1 4.9 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein CPBP PF02517.16 AAAP01003794.1_4 - 1.4 9.4 9.6 2.2 8.7 6.8 2.3 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease NicO PF03824.16 AAAP01003794.1_5 - 7.8e-09 35.3 12.1 8.5e-09 35.2 12.1 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF1905 PF08922.11 AAAP01003794.1_7 - 1.9e-27 95.1 0.0 2.2e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1905) OmpA PF00691.20 AAAP01003794.1_8 - 1.7e-17 63.6 0.0 7.3e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 OmpA family DUF4164 PF13747.6 AAAP01003794.1_8 - 0.0085 16.3 14.9 0.06 13.6 7.0 2.6 1 1 0 2 2 2 2 Domain of unknown function (DUF4164) FlxA PF14282.6 AAAP01003794.1_8 - 0.017 15.1 1.7 0.041 13.9 1.7 1.6 1 0 0 1 1 1 0 FlxA-like protein Golgin_A5 PF09787.9 AAAP01003794.1_8 - 0.092 12.2 6.1 0.13 11.7 6.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 AAAP01003794.1_8 - 0.4 11.3 12.6 0.52 11.0 10.0 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MerR-DNA-bind PF09278.11 AAAP01003794.1_8 - 1.5 9.4 11.7 0.28 11.8 6.9 2.2 2 0 0 2 2 2 0 MerR, DNA binding Apt1 PF10351.9 AAAP01003794.1_8 - 2.2 7.0 4.6 2.7 6.7 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Atg14 PF10186.9 AAAP01003794.1_8 - 4.5 6.3 8.7 6 5.9 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 AAAP01003794.1_8 - 5.6 5.7 11.9 8.4 5.2 11.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MotA_ExbB PF01618.16 AAAP01003794.1_9 - 0.00045 20.0 4.9 0.0064 16.2 4.9 3.0 1 1 1 2 2 2 1 MotA/TolQ/ExbB proton channel family Ribosomal_S15 PF00312.22 AAAP01003794.1_9 - 0.16 12.2 0.7 0.36 11.1 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S15 SlyX PF04102.12 AAAP01003794.1_9 - 3 8.5 4.6 38 5.0 1.1 2.7 2 0 0 2 2 2 0 SlyX DsbB PF02600.16 AAAP01003794.1_9 - 3.7 8.0 5.3 2.7 8.4 1.2 2.1 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB DUF4407 PF14362.6 AAAP01003794.1_9 - 5.3 6.3 6.5 9.8 5.4 1.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 AAAP01003794.1_9 - 7.4 6.9 5.8 5 7.4 0.2 3.2 4 1 0 4 4 4 0 Proteins of 100 residues with WXG OmpA PF00691.20 AAAP01003794.1_10 - 2.7e-09 37.3 0.0 4.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 OmpA family Pilus_CpaD PF09476.10 AAAP01003794.1_10 - 0.004 16.9 0.1 0.0072 16.1 0.1 1.3 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) Inositol_P PF00459.25 AAAP01003794.1_11 - 4.5e-67 226.4 0.0 5.3e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Elong-fact-P_C PF09285.11 AAAP01003794.1_12 - 5.7e-23 80.4 0.9 1e-22 79.6 0.2 1.8 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 AAAP01003794.1_12 - 2.4e-20 72.3 0.7 9.2e-20 70.4 0.1 2.3 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AAAP01003794.1_12 - 2.9e-18 65.7 0.9 1.6e-17 63.3 0.5 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Methyltransf_25 PF13649.6 AAAP01003794.1_13 - 3.8e-13 49.9 0.0 1.2e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003794.1_13 - 7.6e-13 48.6 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003794.1_13 - 9.3e-12 45.5 0.0 4.6e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003794.1_13 - 4.5e-08 33.0 0.0 8e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003794.1_13 - 6.9e-07 29.9 0.0 1.1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 AAAP01003794.1_13 - 0.00038 20.2 0.0 0.00073 19.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Radical_SAM PF04055.21 AAAP01003794.1_14 - 2.3e-09 37.9 0.0 2.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily LAM_C PF12544.8 AAAP01003794.1_14 - 4.5e-07 30.1 0.3 7e-07 29.5 0.3 1.3 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_12 PF13353.6 AAAP01003794.1_14 - 0.00015 22.0 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003794.1_14 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain tRNA-synt_2 PF00152.20 AAAP01003794.1_15 - 4.3e-47 160.7 0.0 5.4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 AAAP01003794.1_15 - 0.00096 18.7 0.0 0.036 13.6 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) DSBA PF01323.20 AAAP01003794.1_16 - 8.6e-26 90.9 2.1 4.2e-25 88.7 0.4 2.4 2 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AAAP01003794.1_16 - 4e-24 85.6 0.0 1.2e-23 84.1 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin ScsC_N PF18312.1 AAAP01003794.1_16 - 1.4e-13 50.4 1.5 1.4e-13 50.4 1.5 2.0 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain Thioredoxin_5 PF13743.6 AAAP01003794.1_16 - 9.9e-07 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAAP01003794.1_16 - 1.5e-06 28.6 0.1 6e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 AAAP01003794.1_16 - 0.004 17.1 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin MHB PF16525.5 AAAP01003794.1_16 - 0.02 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 Haemophore, haem-binding AvrPtoB_bdg PF16847.5 AAAP01003794.1_16 - 0.037 14.5 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain YqfD PF06898.11 AAAP01003794.1_16 - 0.062 12.1 1.5 0.073 11.9 0.2 1.7 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD IIGP PF05049.13 AAAP01003794.1_16 - 0.063 12.3 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) EcoR124_C PF12008.8 AAAP01003794.1_16 - 0.075 12.7 1.0 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF3860 PF12976.7 AAAP01003794.1_16 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) V-ATPase_G_2 PF16999.5 AAAP01003794.1_16 - 1.6 9.2 9.5 0.084 13.3 2.9 2.2 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit TPR_14 PF13428.6 AAAP01003794.1_17 - 1.2e-08 35.1 9.0 0.012 16.4 0.1 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003794.1_17 - 4.2e-06 27.2 6.0 0.057 13.9 1.2 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003794.1_17 - 1e-05 25.1 1.5 0.00068 19.3 0.0 3.1 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 AAAP01003794.1_17 - 1.1e-05 26.0 8.9 0.00016 22.3 0.7 3.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003794.1_17 - 2.8e-05 23.9 10.2 0.35 11.1 0.6 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003794.1_17 - 0.00014 22.0 0.1 4.1 8.0 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003794.1_17 - 0.00015 21.1 1.7 0.0004 19.7 1.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003794.1_17 - 0.00033 20.4 6.7 0.17 11.8 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003794.1_17 - 0.0013 18.9 0.1 0.083 13.1 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 AAAP01003794.1_17 - 0.0057 17.0 1.9 4.9 7.6 0.1 3.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003794.1_17 - 0.29 11.4 3.1 14 6.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SecY PF00344.20 AAAP01003795.1_1 - 2.4e-26 92.7 3.6 2.6e-26 92.6 3.6 1.0 1 0 0 1 1 1 1 SecY translocase Insulin_TMD PF17870.1 AAAP01003795.1_1 - 0.53 10.4 6.6 0.13 12.4 1.8 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Ribosomal_L27A PF00828.19 AAAP01003795.1_3 - 5.4e-37 127.3 3.8 6.4e-37 127.1 3.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L30 PF00327.20 AAAP01003795.1_4 - 4.4e-18 64.9 0.0 5.4e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 AAAP01003795.1_5 - 6.2e-30 102.5 0.2 1e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AAAP01003795.1_5 - 9e-29 99.3 4.7 1.7e-28 98.4 4.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L18p PF00861.22 AAAP01003795.1_6 - 1e-43 148.4 2.1 1.1e-43 148.3 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L6 PF00347.23 AAAP01003795.1_7 - 6e-40 135.8 1.4 2.6e-19 69.7 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S8 PF00410.19 AAAP01003795.1_8 - 1.5e-44 151.0 0.0 1.7e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 AAAP01003795.1_9 - 1.5e-24 85.5 2.2 2.7e-24 84.7 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e SpoIIIAH PF12685.7 AAAP01003795.1_9 - 0.2 11.5 0.5 0.25 11.2 0.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Ribosomal_L5_C PF00673.21 AAAP01003795.1_10 - 9.2e-43 144.4 0.0 1.4e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AAAP01003795.1_10 - 2.4e-28 98.3 0.9 4.3e-28 97.4 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 ribosomal_L24 PF17136.4 AAAP01003795.1_11 - 6.3e-26 90.6 1.3 6.3e-26 90.6 1.3 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AAAP01003795.1_11 - 3.2e-05 23.7 1.2 3.2e-05 23.7 1.2 1.9 2 0 0 2 2 2 1 KOW motif DUF1918 PF08940.11 AAAP01003795.1_11 - 0.65 9.7 5.1 6.9 6.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) Ribosomal_L14 PF00238.19 AAAP01003795.1_12 - 1.5e-54 183.3 3.1 1.6e-54 183.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 AAAP01003795.1_13 - 6.1e-32 109.5 6.1 6.9e-32 109.4 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L29 PF00831.23 AAAP01003795.1_14 - 7.4e-24 83.5 4.4 8.3e-24 83.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 AAAP01003795.1_14 - 0.0015 18.6 0.2 0.002 18.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) CdvA PF18822.1 AAAP01003795.1_14 - 0.023 14.5 0.5 0.046 13.6 0.4 1.6 1 1 0 1 1 1 0 CdvA-like coiled-coil domain APC_N_CC PF16689.5 AAAP01003795.1_14 - 0.087 12.9 0.6 0.13 12.3 0.6 1.6 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1192 PF06698.11 AAAP01003795.1_14 - 0.13 12.3 3.9 0.49 10.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) FlgM PF04316.13 AAAP01003795.1_14 - 0.44 10.9 3.4 5.9 7.3 0.4 2.2 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM Ribosomal_L16 PF00252.18 AAAP01003795.1_15 - 5.6e-49 165.5 0.4 6.3e-49 165.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.20 AAAP01003795.1_16 - 8.9e-40 135.1 0.7 1.9e-39 134.1 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AAAP01003795.1_16 - 1.1e-21 76.4 2.3 2.4e-21 75.3 2.3 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AAAP01003795.1_16 - 0.036 14.0 0.1 0.071 13.0 0.1 1.5 1 0 0 1 1 1 0 KH domain Ribosomal_L22 PF00237.19 AAAP01003795.1_17 - 1.2e-29 102.6 0.5 1.4e-29 102.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Gp58 PF07902.11 AAAP01003795.1_17 - 0.074 11.3 0.1 0.078 11.3 0.1 1.0 1 0 0 1 1 1 0 gp58-like protein DUF1173 PF06666.11 AAAP01003795.1_17 - 0.087 11.7 0.8 0.087 11.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Ribosomal_S19 PF00203.21 AAAP01003795.1_18 - 1.5e-34 117.7 0.0 1.7e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 AAAP01003795.1_19 - 7.4e-58 194.2 3.4 1.3e-57 193.5 3.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AAAP01003795.1_19 - 4.1e-32 110.0 0.5 7.8e-32 109.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 AAAP01003795.1_20 - 6.6e-32 109.7 0.4 7.7e-32 109.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 VWA PF00092.28 AAAP01003795.1_20 - 0.029 14.6 0.0 0.034 14.4 0.0 1.0 1 0 0 1 1 1 0 von Willebrand factor type A domain Ribosomal_L4 PF00573.22 AAAP01003795.1_21 - 4.4e-63 212.4 0.1 5e-63 212.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 AAAP01003795.1_22 - 7.9e-19 67.9 6.5 2.9e-16 59.4 3.5 2.6 1 1 2 3 3 3 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 AAAP01003795.1_23 - 2.3e-37 127.2 0.2 2.5e-37 127.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MazE_antitoxin PF04014.18 AAAP01003795.1_24 - 3.5e-10 39.5 0.1 4.9e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PIN PF01850.21 AAAP01003795.1_25 - 2.1e-16 60.5 0.0 2.4e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.6 AAAP01003795.1_25 - 0.027 14.4 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) GTP_EFTU PF00009.27 AAAP01003795.1_27 - 4.2e-56 189.6 0.0 5.6e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AAAP01003795.1_27 - 5.2e-33 113.7 0.0 1.2e-32 112.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AAAP01003795.1_27 - 7.7e-17 61.5 6.3 3.6e-16 59.3 6.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAAP01003795.1_27 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 AAAP01003795.1_27 - 0.051 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Lsm_C PF14894.6 AAAP01003795.1_27 - 0.28 11.0 4.2 0.6 9.9 4.2 1.5 1 0 0 1 1 1 0 Lsm C-terminal SpoU_methylase PF00588.19 AAAP01003795.1_28 - 5.3e-38 130.4 0.1 9.1e-38 129.6 0.0 1.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AAAP01003795.1_28 - 1.5e-11 44.4 0.0 3.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Rab_eff_C PF04698.12 AAAP01003795.1_30 - 0.21 9.8 0.0 0.25 9.6 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus SBP_bac_3 PF00497.20 AAAP01003795.1_31 - 1.4e-57 194.7 0.0 2.1e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AAAP01003795.1_31 - 1.1e-10 41.7 0.0 3.3e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 AAAP01003795.1_31 - 5.8e-08 32.7 0.0 9.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel NMT1 PF09084.11 AAAP01003795.1_31 - 0.007 16.3 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAAP01003795.1_31 - 0.0092 15.6 0.2 0.63 9.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4148 PF13663.6 AAAP01003795.1_31 - 1.7 8.9 5.6 6.5 7.0 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Lactamase_B PF00753.27 AAAP01003796.1_2 - 1.8e-13 51.0 0.0 2.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01003796.1_2 - 0.043 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MCPsignal PF00015.21 AAAP01003796.1_3 - 1.8e-09 37.7 4.5 0.00046 20.1 0.8 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Jnk-SapK_ap_N PF09744.9 AAAP01003796.1_3 - 5.9e-05 23.3 0.1 0.00026 21.2 0.0 1.9 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 DASH_Dad2 PF08654.10 AAAP01003796.1_3 - 0.017 15.5 3.2 0.61 10.5 0.3 3.2 2 1 0 3 3 3 0 DASH complex subunit Dad2 CdvA PF18822.1 AAAP01003796.1_3 - 0.022 14.6 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain HisKA_3 PF07730.13 AAAP01003796.1_3 - 0.029 14.9 12.0 2.5 8.7 0.4 4.2 4 0 0 4 4 4 0 Histidine kinase WXG100 PF06013.12 AAAP01003796.1_3 - 0.1 12.8 0.6 11 6.3 0.0 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Apolipoprotein PF01442.18 AAAP01003796.1_3 - 0.12 12.2 4.8 0.23 11.3 0.6 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MutS_III PF05192.18 AAAP01003796.1_3 - 0.22 11.7 1.7 0.29 11.4 1.7 1.2 1 0 0 1 1 1 0 MutS domain III MM_CoA_mutase PF01642.22 AAAP01003796.1_5 - 3e-244 811.3 0.8 3.6e-244 811.1 0.8 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 AAAP01003796.1_5 - 1e-14 54.6 0.3 2.4e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 AAAP01003796.1_5 - 0.13 12.5 0.1 0.89 9.7 0.0 2.4 2 0 0 2 2 2 0 HisG, C-terminal domain Pro_CA PF00484.19 AAAP01003796.1_6 - 2.3e-51 174.2 1.0 2.8e-51 173.9 1.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 AAAP01003796.1_6 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily Biotin_carb_C PF02785.19 AAAP01003796.1_7 - 7.7e-41 138.6 0.0 2.2e-40 137.1 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 AAAP01003796.1_7 - 2e-32 112.2 0.0 3e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 AAAP01003796.1_7 - 6.2e-16 58.0 0.3 2.4e-15 56.1 0.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAAP01003796.1_7 - 6.6e-07 29.1 0.0 6.8e-06 25.8 0.0 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like QRPTase_N PF02749.16 AAAP01003796.1_7 - 0.0029 17.6 0.0 0.0093 16.0 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_3 PF13437.6 AAAP01003796.1_7 - 0.11 13.2 0.1 2.4 8.9 0.0 2.6 2 1 1 3 3 3 0 HlyD family secretion protein PTS_EIIA_1 PF00358.20 AAAP01003796.1_7 - 0.14 11.9 0.1 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 CPSase_L_D2 PF02786.17 AAAP01003796.1_8 - 3.8e-58 196.4 0.2 1.9e-57 194.2 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAAP01003796.1_8 - 5.1e-45 152.5 0.4 1.1e-44 151.5 0.4 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 AAAP01003796.1_8 - 4.1e-07 29.7 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AAAP01003796.1_8 - 6.1e-07 29.2 0.3 4.3e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AAAP01003796.1_8 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AAAP01003796.1_8 - 0.00027 20.8 1.2 0.00065 19.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 AAAP01003796.1_8 - 0.047 13.7 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 AAAP01003796.1_8 - 0.053 13.1 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DNA_photolyase PF00875.18 AAAP01003796.1_8 - 0.13 12.2 0.0 0.6 10.1 0.0 1.9 2 0 0 2 2 2 0 DNA photolyase Carboxyl_trans PF01039.22 AAAP01003796.1_9 - 1.4e-199 663.9 0.0 1.6e-199 663.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAAP01003796.1_9 - 0.1 12.1 0.5 1 8.8 0.0 2.3 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) NUC130_3NT PF08158.12 AAAP01003796.1_9 - 0.13 12.6 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 NUC130/3NT domain DUF2083 PF09856.9 AAAP01003796.1_10 - 1.2e-71 239.6 0.1 2.2e-71 238.8 0.1 1.4 1 0 0 1 1 1 1 Predicted transcriptional regulator (DUF2083) Peptidase_M78 PF06114.13 AAAP01003796.1_10 - 1.7e-17 63.5 0.3 5.5e-17 61.8 0.0 2.0 2 1 1 3 3 3 1 IrrE N-terminal-like domain HTH_3 PF01381.22 AAAP01003796.1_10 - 8.7e-15 54.5 0.2 1.7e-14 53.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003796.1_10 - 8.6e-13 48.4 1.5 2.7e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003796.1_10 - 1e-11 44.7 0.1 2.9e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01003796.1_10 - 1.7e-05 24.7 0.2 3.8e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003796.1_10 - 3.8e-05 24.0 0.1 7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AAAP01003796.1_10 - 5.5e-05 22.9 0.2 0.00015 21.5 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-T_C PF15511.6 AAAP01003796.1_10 - 0.076 13.1 0.1 12 6.1 0.0 2.6 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T histone fold CinA_KH PF18146.1 AAAP01003796.1_10 - 0.14 12.3 0.0 0.89 9.8 0.0 2.3 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain B12-binding PF02310.19 AAAP01003797.1_3 - 1.5e-18 67.0 0.4 4.8e-18 65.3 0.1 2.0 2 0 0 2 2 2 1 B12 binding domain Radical_SAM PF04055.21 AAAP01003797.1_3 - 3.3e-18 66.6 0.3 2.4e-17 63.8 0.3 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Aldo_ket_red PF00248.21 AAAP01003797.1_3 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family Methyltransf_11 PF08241.12 AAAP01003797.1_4 - 1.7e-14 54.2 0.0 3.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003797.1_4 - 2.1e-13 50.8 0.0 7.7e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003797.1_4 - 3.2e-13 49.9 0.0 6.9e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003797.1_4 - 1.5e-08 35.2 0.0 3.5e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003797.1_4 - 4e-07 29.9 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003797.1_4 - 2.2e-05 23.9 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 AAAP01003797.1_4 - 0.0001 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 AAAP01003797.1_4 - 0.00032 20.3 0.0 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 AAAP01003797.1_4 - 0.0026 17.2 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 AAAP01003797.1_4 - 0.023 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 AAAP01003797.1_4 - 0.16 10.5 0.0 9.4 4.7 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase GidB PF02527.15 AAAP01003797.1_4 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Glycos_transf_2 PF00535.26 AAAP01003797.1_5 - 2.4e-22 79.6 0.0 3.7e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003797.1_5 - 1.8e-13 50.9 2.5 2.3e-11 44.1 2.5 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003797.1_5 - 8.9e-09 35.2 0.0 7.5e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 AAAP01003797.1_5 - 0.0017 18.0 1.5 0.0045 16.6 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 AAAP01003797.1_5 - 0.1 12.1 0.0 4.1 6.8 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferase family 21 Methyltransf_11 PF08241.12 AAAP01003797.1_6 - 1.6e-14 54.3 0.0 2.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003797.1_6 - 8.1e-13 48.9 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003797.1_6 - 1.6e-06 28.1 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003797.1_6 - 2.6e-05 24.9 0.0 4.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003797.1_6 - 3.5e-05 23.7 0.0 4.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 AAAP01003797.1_6 - 0.00039 19.1 0.0 0.00049 18.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 AAAP01003797.1_6 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAAP01003797.1_6 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Asn_synthase PF00733.21 AAAP01003797.1_7 - 1.9e-92 310.6 0.1 2.4e-92 310.3 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003797.1_7 - 1.3e-47 160.8 0.0 2.1e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003797.1_7 - 1.4e-39 135.3 0.0 2.9e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 AAAP01003797.1_7 - 0.00013 21.5 0.0 0.00031 20.3 0.0 1.5 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC DUF3700 PF12481.8 AAAP01003797.1_7 - 0.00028 20.4 0.0 0.00066 19.2 0.0 1.6 1 1 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 AAAP01003797.1_7 - 0.065 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.17 AAAP01003797.1_7 - 0.077 12.1 0.0 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 NAD synthase ATP_bind_3 PF01171.20 AAAP01003797.1_7 - 0.19 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Glycos_transf_1 PF00534.20 AAAP01003797.1_8 - 2.1e-09 37.2 0.0 3.5e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003797.1_8 - 3.3e-08 34.0 0.0 5.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003797.1_8 - 1.9e-06 28.1 0.0 4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Radical_SAM PF04055.21 AAAP01003797.1_9 - 2.3e-23 83.4 0.1 9.5e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003797.1_9 - 4.5e-06 26.7 0.1 9.4e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 B12 binding domain Fer4_12 PF13353.6 AAAP01003797.1_9 - 0.0065 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain RhoGAP-FF1 PF16512.5 AAAP01003797.1_9 - 0.041 14.6 0.0 0.54 11.0 0.0 2.5 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain ARL2_Bind_BART PF11527.8 AAAP01003797.1_9 - 0.05 13.7 0.1 22 5.2 0.0 3.2 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART Radical_SAM PF04055.21 AAAP01003797.1_10 - 4.8e-20 72.6 1.5 6.4e-20 72.2 0.7 1.7 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003797.1_10 - 5.3e-19 68.4 0.0 9.9e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain Ribosomal_L4 PF00573.22 AAAP01003797.1_10 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Radical_SAM_N PF08497.10 AAAP01003797.1_10 - 0.025 13.9 0.0 0.24 10.6 0.0 2.4 2 1 0 2 2 2 0 Radical SAM N-terminal AP_endonuc_2 PF01261.24 AAAP01003797.1_10 - 0.091 12.2 0.0 0.89 9.0 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Rubi_NSP_C PF12601.8 AAAP01003797.1_10 - 0.16 12.1 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein Glycos_transf_2 PF00535.26 AAAP01003797.1_11 - 1.6e-33 115.9 0.0 2.2e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003797.1_11 - 3.3e-21 76.2 0.0 4.9e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003797.1_11 - 1.1e-06 28.4 0.0 2.7e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003797.1_11 - 6.1e-06 26.7 0.0 2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAAP01003797.1_11 - 0.0001 22.3 2.1 0.00054 19.9 2.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_5 PF13712.6 AAAP01003797.1_11 - 0.0032 17.2 0.0 0.072 12.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family Glyco_transf_21 PF13506.6 AAAP01003797.1_11 - 0.013 15.0 0.0 0.03 13.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 B12-binding PF02310.19 AAAP01003797.1_12 - 3.4e-06 27.1 0.0 5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain GATase PF00117.28 AAAP01003798.1_1 - 1.8e-40 138.7 0.0 2.5e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01003798.1_1 - 2.8e-10 40.3 0.0 9.6e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 AAAP01003798.1_1 - 1.1e-09 37.8 0.3 3.5e-06 26.3 0.1 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 AAAP01003798.1_1 - 7.9e-06 24.9 0.2 3.4e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 AAAP01003798.1_1 - 0.00078 19.2 0.4 0.0015 18.3 0.4 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AAAP01003798.1_1 - 0.0019 17.7 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AAAP01003798.1_1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 AAAP01003798.1_1 - 0.027 14.0 0.1 0.069 12.7 0.1 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 AAAP01003798.1_1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MlaC PF05494.12 AAAP01003798.1_3 - 5.3e-24 84.8 0.0 6.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 MlaC protein tRNA_edit PF04073.15 AAAP01003798.1_4 - 2.1e-29 102.1 0.0 2.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain EAL PF00563.20 AAAP01003798.1_5 - 1.2e-60 205.0 0.0 2.8e-60 203.8 0.0 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003798.1_5 - 2.5e-44 150.9 0.0 3.9e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF3365 PF11845.8 AAAP01003798.1_5 - 3.2e-05 24.3 0.0 0.00038 20.8 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3365) GGDEF_2 PF17853.1 AAAP01003798.1_5 - 0.017 15.4 1.0 0.48 10.7 0.1 2.8 2 0 0 2 2 2 0 GGDEF-like domain MCPsignal PF00015.21 AAAP01003798.1_6 - 1.5e-29 103.0 30.5 1.5e-29 103.0 30.5 3.7 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003798.1_6 - 1.4e-09 38.2 0.2 1.4e-09 38.2 0.2 5.0 5 1 0 5 5 5 1 HAMP domain 4HB_MCP_1 PF12729.7 AAAP01003798.1_6 - 6.2e-06 25.9 0.1 6.2e-06 25.9 0.1 3.8 3 2 0 3 3 3 1 Four helix bundle sensory module for signal transduction V_ATPase_I PF01496.19 AAAP01003798.1_6 - 0.016 13.2 9.0 0.024 12.6 9.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cas_DxTHG PF09455.10 AAAP01003798.1_6 - 0.13 11.8 0.3 0.22 11.1 0.3 1.5 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family CorA PF01544.18 AAAP01003798.1_6 - 0.17 11.2 6.1 0.74 9.1 1.0 3.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 AAAP01003798.1_6 - 0.68 10.0 15.2 6.4 6.8 3.6 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 AAAP01003798.1_6 - 2.8 8.4 6.5 15 6.0 3.3 3.8 2 1 2 4 4 4 0 Syntaxin-like protein TMPIT PF07851.13 AAAP01003798.1_6 - 5.7 6.1 6.7 3.1 7.0 0.4 2.6 1 1 1 3 3 3 0 TMPIT-like protein PrmA PF06325.13 AAAP01003798.1_7 - 5.4e-55 186.9 0.0 5.7e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01003798.1_7 - 1.1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAAP01003798.1_7 - 1e-07 32.6 0.0 2.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AAAP01003798.1_7 - 4e-06 26.7 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 AAAP01003798.1_7 - 7.8e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AAAP01003798.1_7 - 1.3e-05 25.0 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 AAAP01003798.1_7 - 2e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 AAAP01003798.1_7 - 0.00083 19.2 0.0 0.0034 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003798.1_7 - 0.0048 17.5 0.0 0.011 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAAP01003798.1_7 - 0.01 15.6 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 AAAP01003798.1_7 - 0.031 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NNMT_PNMT_TEMT PF01234.17 AAAP01003798.1_7 - 0.04 13.1 0.0 6.1 6.0 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_18 PF12847.7 AAAP01003798.1_7 - 0.048 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 AAAP01003798.1_7 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 TRM PF02005.16 AAAP01003798.1_7 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_32 PF13679.6 AAAP01003798.1_7 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 AAAP01003798.1_7 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G UvrD-helicase PF00580.21 AAAP01003798.1_8 - 2.9e-70 237.3 0.0 1.4e-69 235.0 0.0 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AAAP01003798.1_8 - 1.6e-60 205.4 0.0 2.1e-59 201.6 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAAP01003798.1_8 - 3.4e-30 105.3 0.2 3.2e-29 102.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 AAAP01003798.1_8 - 8.5e-10 38.3 0.2 3.9e-09 36.2 0.2 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAAP01003798.1_8 - 2.8e-09 37.0 1.8 1.8e-06 27.8 0.3 3.5 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AAAP01003798.1_8 - 2.2e-07 30.9 0.0 0.076 12.7 0.0 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DinB_2 PF12867.7 AAAP01003798.1_8 - 0.04 14.4 1.4 0.1 13.1 0.3 2.4 2 0 0 2 2 2 0 DinB superfamily AAA_16 PF13191.6 AAAP01003798.1_8 - 0.2 12.1 3.6 0.33 11.3 1.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain Hemerythrin PF01814.23 AAAP01003798.1_10 - 9.6e-08 32.7 0.4 2.2e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Response_reg PF00072.24 AAAP01003798.1_10 - 6.2e-07 29.6 0.0 4e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 Response regulator receiver domain BPL_LplA_LipB PF03099.19 AAAP01003798.1_11 - 2.2e-08 34.1 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family malic PF00390.19 AAAP01003798.1_12 - 1.2e-26 93.6 0.6 2e-23 83.2 0.7 2.9 2 1 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 AAAP01003798.1_12 - 1.4e-23 83.5 1.2 4.9e-23 81.7 1.2 1.8 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain PTA_PTB PF01515.19 AAAP01003798.1_12 - 0.0046 16.3 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase Malate_DH PF12434.8 AAAP01003798.1_12 - 0.025 14.6 0.3 0.055 13.5 0.3 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme AlaDh_PNT_C PF01262.21 AAAP01003798.1_12 - 0.026 13.8 1.3 0.049 12.9 1.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HD_5 PF13487.6 AAAP01003799.1_1 - 1.6e-20 73.1 0.1 3.4e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 HD domain HD PF01966.22 AAAP01003799.1_1 - 7.9e-06 26.1 0.1 2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 HD domain Pox_I6 PF04595.13 AAAP01003799.1_1 - 0.076 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family HATPase_c PF02518.26 AAAP01003799.1_2 - 1.5e-25 89.9 0.0 2.6e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003799.1_2 - 8.3e-22 77.5 0.1 5.5e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01003799.1_2 - 1.5e-15 57.2 0.0 1.8e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003799.1_2 - 1.4e-13 51.0 0.0 3.3e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 AAAP01003799.1_2 - 1.3e-12 47.6 1.7 1.9e-12 47.0 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003799.1_2 - 4.3e-11 42.6 0.0 0.00026 20.9 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AAAP01003799.1_2 - 3.1e-10 40.2 0.0 2.1e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 AAAP01003799.1_2 - 0.0037 17.1 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Far-17a_AIG1 PF04750.14 AAAP01003799.1_2 - 0.43 9.8 3.4 0.81 9.0 3.4 1.3 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein GSHPx PF00255.19 AAAP01003799.1_3 - 7.3e-32 109.2 0.0 9.7e-32 108.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AAAP01003799.1_3 - 0.017 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF520 PF04461.13 AAAP01003799.1_6 - 6.5e-61 205.2 6.5 7.2e-61 205.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) DUF1948 PF09185.10 AAAP01003799.1_6 - 0.005 16.7 0.3 0.0077 16.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1948) DUF2120 PF09893.9 AAAP01003799.1_6 - 0.043 13.9 0.6 0.061 13.4 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) MCPsignal PF00015.21 AAAP01003799.1_7 - 1.7e-34 119.1 38.2 2.3e-33 115.4 20.0 3.6 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain CZB PF13682.6 AAAP01003799.1_7 - 1e-13 51.5 0.2 2.1e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain DUF948 PF06103.11 AAAP01003799.1_7 - 0.00036 20.7 22.8 0.016 15.5 3.8 4.6 2 2 3 5 5 5 3 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 AAAP01003799.1_7 - 0.39 10.3 10.3 0.12 12.0 5.5 2.5 1 1 0 2 2 2 0 Snf7 DUF3739 PF12545.8 AAAP01003799.1_7 - 0.42 11.1 4.8 1 9.9 3.8 2.1 1 1 1 2 2 2 0 Filamentous haemagglutinin family outer membrane protein T2SSF PF00482.23 AAAP01003799.1_7 - 0.44 10.5 16.4 0.11 12.5 1.0 4.2 1 1 2 4 4 4 0 Type II secretion system (T2SS), protein F NPV_P10 PF05531.12 AAAP01003799.1_7 - 0.45 11.0 16.5 6.2 7.4 0.0 5.2 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein DHR10 PF18595.1 AAAP01003799.1_7 - 0.5 10.4 13.6 0.12 12.4 1.3 4.3 3 2 2 5 5 4 0 Designed helical repeat protein 10 domain Serine_rich PF08824.10 AAAP01003799.1_7 - 0.57 10.2 11.7 1.1 9.2 2.5 3.3 1 1 3 4 4 4 0 Serine rich protein interaction domain Sec34 PF04136.15 AAAP01003799.1_7 - 0.65 9.9 11.0 17 5.2 0.3 4.5 2 2 2 4 4 4 0 Sec34-like family Fib_alpha PF08702.10 AAAP01003799.1_7 - 0.84 9.8 14.1 0.63 10.2 2.6 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 AAAP01003799.1_7 - 0.94 9.5 22.4 3.8 7.5 6.9 4.0 3 2 0 3 3 3 0 Laminin Domain II D5_N PF08706.11 AAAP01003799.1_7 - 0.95 9.7 2.7 0.7 10.2 0.5 1.9 2 1 0 2 2 2 0 D5 N terminal like BLOC1_2 PF10046.9 AAAP01003799.1_7 - 1.1 9.7 12.9 4.5 7.7 0.2 5.1 4 1 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 AAAP01003799.1_7 - 2.2 8.3 21.0 34 4.5 0.3 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) COMP PF11598.8 AAAP01003799.1_7 - 3.3 8.2 4.8 5.7 7.5 0.4 3.2 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Bep_C_terminal PF17841.1 AAAP01003799.1_7 - 4.1 7.7 9.0 15 5.9 0.3 4.4 5 0 0 5 5 4 0 BID domain of Bartonella effector protein (Bep) TMPIT PF07851.13 AAAP01003799.1_7 - 5.2 6.2 7.9 4.8 6.3 1.3 2.4 1 1 0 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 AAAP01003799.1_7 - 6.8 7.4 15.6 6.6 7.5 2.9 3.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lipoprotein_7 PF01540.16 AAAP01003799.1_7 - 7.2 5.8 9.4 6.5 5.9 4.5 2.1 1 1 1 2 2 2 0 Adhesin lipoprotein WXG100 PF06013.12 AAAP01003799.1_7 - 8.8 6.6 22.3 3 8.1 0.2 5.6 3 1 3 6 6 6 0 Proteins of 100 residues with WXG DUF16 PF01519.16 AAAP01003799.1_7 - 9 6.8 7.0 6.5 7.3 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 SpoIIE PF07228.12 AAAP01003799.1_8 - 1.3e-30 106.8 0.0 2.1e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAAP01003799.1_8 - 7.2e-28 97.0 0.0 1.1e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAAP01003799.1_8 - 8.1e-05 22.6 0.1 0.00086 19.3 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain STAS_2 PF13466.6 AAAP01003799.1_9 - 1.1e-12 48.1 0.2 1.2e-12 48.0 0.2 1.0 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003799.1_9 - 5.4e-08 32.5 0.0 5.6e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 STAS domain Methyltransf_25 PF13649.6 AAAP01003799.1_10 - 2e-06 28.4 0.0 7.9e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAAP01003799.1_10 - 2.8e-06 26.8 0.0 3.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003799.1_10 - 1.1e-05 26.0 0.0 2.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003799.1_10 - 4.4e-05 24.1 0.0 0.00011 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003799.1_10 - 0.0018 18.1 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003799.1_10 - 0.0029 17.4 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AAAP01003799.1_10 - 0.036 14.1 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain LCM PF04072.14 AAAP01003799.1_10 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase tRNA-synt_2b PF00587.25 AAAP01003799.1_11 - 4.1e-13 49.7 0.0 8.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 AAAP01003799.1_11 - 1.5e-10 41.1 0.0 3.8e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 AAAP01003799.1_11 - 0.00026 21.1 0.0 0.0007 19.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain DoxX PF07681.12 AAAP01003799.1_12 - 8.6e-17 61.5 13.2 1.7e-16 60.6 13.2 1.4 1 0 0 1 1 1 1 DoxX DoxD PF04173.13 AAAP01003799.1_12 - 0.001 19.0 1.1 0.0014 18.5 1.1 1.2 1 0 0 1 1 1 1 TQO small subunit DoxD DoxX_2 PF13564.6 AAAP01003799.1_12 - 0.38 10.9 11.7 0.84 9.8 11.8 1.8 1 1 0 1 1 1 0 DoxX-like family MlaC PF05494.12 AAAP01003799.1_13 - 4.7e-22 78.5 0.1 7.9e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 MlaC protein HPTransfase PF10090.9 AAAP01003799.1_13 - 0.17 11.7 0.2 0.17 11.7 0.2 2.0 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain PRIMA1 PF16101.5 AAAP01003799.1_13 - 7.6 6.6 8.2 13 5.8 8.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Transglut_core PF01841.19 AAAP01003799.1_14 - 5.2e-21 75.2 0.0 6.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AAAP01003799.1_14 - 0.031 13.8 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain Ribosomal_S18 PF01084.20 AAAP01003800.1_1 - 2.9e-12 46.6 0.5 3.1e-12 46.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S18 DUF2232 PF09991.9 AAAP01003800.1_2 - 8e-07 28.5 16.4 9.9e-06 24.9 0.3 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2232) Ribosomal_L9_C PF03948.14 AAAP01003800.1_3 - 1.4e-25 89.5 0.0 3.5e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AAAP01003800.1_3 - 3.9e-22 77.5 0.2 1.2e-21 75.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain FDF PF09532.10 AAAP01003800.1_3 - 0.24 12.3 2.3 0.75 10.7 0.0 2.1 2 0 0 2 2 2 0 FDF domain DnaB PF00772.21 AAAP01003800.1_4 - 2.5e-31 107.8 0.0 3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain DnaB_C PF03796.15 AAAP01003800.1_5 - 4.3e-107 357.2 0.2 5.2e-107 356.9 0.2 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 AAAP01003800.1_5 - 2e-14 53.7 0.0 3.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AAAP01003800.1_5 - 0.00061 19.2 0.1 0.0016 17.8 0.1 1.9 1 1 0 1 1 1 1 KaiC AAA PF00004.29 AAAP01003800.1_5 - 0.0031 17.9 0.4 0.059 13.8 0.4 2.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01003800.1_5 - 0.0055 17.1 0.7 0.022 15.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 AAAP01003800.1_5 - 0.04 14.5 1.0 91 3.6 0.1 3.7 2 2 1 3 3 3 0 AAA domain FtsX PF02687.21 AAAP01003800.1_6 - 0.13 12.8 6.1 0.049 14.1 2.1 2.0 2 0 0 2 2 2 0 FtsX-like permease family Ala_racemase_N PF01168.20 AAAP01003800.1_7 - 2.1e-50 171.4 0.1 2.5e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AAAP01003800.1_7 - 5e-35 120.0 0.0 6.9e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain MlaE PF02405.16 AAAP01003800.1_8 - 1.4e-79 266.7 21.9 2e-79 266.2 21.9 1.2 1 0 0 1 1 1 1 Permease MlaE SBP_bac_3 PF00497.20 AAAP01003800.1_10 - 3.8e-15 55.9 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 TctC PF03401.14 AAAP01003800.1_10 - 0.16 11.0 0.0 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor AAA_25 PF13481.6 AAAP01003800.1_11 - 2.3e-14 53.4 0.3 5.7e-14 52.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AAAP01003800.1_11 - 9.6e-10 38.2 0.0 0.00075 18.9 0.0 2.2 1 1 1 2 2 2 2 KaiC ChlI PF13541.6 AAAP01003800.1_11 - 4.8e-09 36.1 0.0 9.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 AAAP01003800.1_11 - 1.3e-06 28.1 0.1 2.9e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_16 PF13191.6 AAAP01003800.1_11 - 2.7e-06 27.9 0.1 6.8e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAAP01003800.1_11 - 0.00021 21.1 0.0 0.00078 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01003800.1_11 - 0.00025 21.5 0.0 0.0004 20.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003800.1_11 - 0.00039 20.7 0.0 0.001 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain GvpD PF07088.11 AAAP01003800.1_11 - 0.00055 18.7 0.0 0.087 11.4 0.0 2.1 1 1 1 2 2 2 2 GvpD gas vesicle protein DnaB_C PF03796.15 AAAP01003800.1_11 - 0.0029 17.0 0.1 0.02 14.2 0.0 1.9 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 AAAP01003800.1_11 - 0.0033 17.4 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 NTPase DUF2075 PF09848.9 AAAP01003800.1_11 - 0.013 14.7 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RecA PF00154.21 AAAP01003800.1_11 - 0.032 13.7 0.2 0.043 13.3 0.2 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein CBM_25 PF03423.13 AAAP01003800.1_11 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAA_5 PF07728.14 AAAP01003800.1_11 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AAAP01003800.1_11 - 0.069 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAAP01003800.1_11 - 0.2 11.3 0.0 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Colicin_V PF02674.16 AAAP01003800.1_12 - 3.8e-33 114.5 7.6 4.7e-33 114.2 7.6 1.1 1 0 0 1 1 1 1 Colicin V production protein HemY_N PF07219.13 AAAP01003800.1_12 - 0.078 13.2 0.2 0.078 13.2 0.2 2.8 3 0 0 3 3 3 0 HemY protein N-terminus GATase_6 PF13522.6 AAAP01003800.1_13 - 3.6e-19 69.3 0.0 7.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAAP01003800.1_13 - 9.1e-19 67.6 0.0 2.3e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AAAP01003800.1_13 - 6.6e-10 38.7 0.4 1.1e-09 38.0 0.4 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AAAP01003800.1_13 - 8.5e-06 24.9 0.1 1.5e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 AAAP01003800.1_13 - 0.082 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase MctB PF11382.8 AAAP01003800.1_13 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB adh_short PF00106.25 AAAP01003800.1_14 - 5e-43 146.8 0.0 5.6e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003800.1_14 - 4.5e-36 124.6 0.3 6.7e-36 124.0 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003800.1_14 - 7.9e-14 52.0 0.2 1.1e-13 51.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003800.1_14 - 1.5e-05 24.6 0.1 6.6e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AAAP01003800.1_14 - 0.005 16.7 0.6 0.015 15.2 0.2 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 AAAP01003800.1_14 - 0.069 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 AAAP01003800.1_14 - 0.13 11.3 0.3 0.56 9.3 0.0 2.1 3 0 0 3 3 3 0 RmlD substrate binding domain Trypsin PF00089.26 AAAP01003800.1_16 - 9.5e-15 55.0 0.0 1.8e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 AAAP01003800.1_16 - 4.6e-09 37.3 0.0 7.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 AAAP01003800.1_16 - 0.11 11.1 0.0 0.67 8.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 Mito_fiss_Elm1 PF06258.11 AAAP01003800.1_17 - 9.1e-95 317.3 0.0 1e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 KAAG1 PF15354.6 AAAP01003800.1_17 - 6.5 7.4 10.1 4.8 7.8 0.5 3.5 3 1 1 4 4 4 0 Kidney-associated antigen 1 AphA_like PF14557.6 AAAP01003800.1_18 - 1e-73 246.7 2.3 1.2e-73 246.6 2.3 1.0 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator Acyl_transf_3 PF01757.22 AAAP01003800.1_19 - 8.5e-19 67.8 31.0 1.7e-18 66.8 31.0 1.4 1 1 0 1 1 1 1 Acyltransferase family DnaB_C PF03796.15 AAAP01003801.1_1 - 7e-98 327.0 0.0 9.1e-98 326.6 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 AAAP01003801.1_1 - 2.3e-12 46.9 0.1 4.5e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AAAP01003801.1_1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 KaiC AAA PF00004.29 AAAP01003801.1_4 - 8e-20 71.6 0.0 1.3e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003801.1_4 - 9.8e-05 22.4 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AAAP01003801.1_4 - 0.00072 19.8 1.0 0.013 15.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003801.1_4 - 0.0021 18.5 0.2 0.0064 16.9 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Vps36_ESCRT-II PF11605.8 AAAP01003801.1_4 - 0.014 15.6 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_30 PF13604.6 AAAP01003801.1_4 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01003801.1_4 - 0.083 13.2 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Polysacc_deac_2 PF04748.13 AAAP01003801.1_4 - 0.086 12.0 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF4505 PF14956.6 AAAP01003801.1_4 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) ATPase PF06745.13 AAAP01003801.1_4 - 0.093 12.1 0.6 4.8 6.5 0.2 2.3 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 AAAP01003801.1_4 - 0.17 11.2 0.1 0.4 10.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsZ_C PF12327.8 AAAP01003801.1_7 - 3.2e-34 117.1 0.6 8e-34 115.8 0.6 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin PF00091.25 AAAP01003801.1_7 - 1.1e-28 100.8 0.0 2e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain NAD_binding_10 PF13460.6 AAAP01003801.1_7 - 0.033 14.1 0.4 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H-binding ADP_ribosyl_GH PF03747.14 AAAP01003801.1_8 - 7.7e-15 55.4 4.3 7.7e-15 55.4 4.3 2.8 1 1 1 2 2 2 1 ADP-ribosylglycohydrolase SpoVG PF04026.12 AAAP01003801.1_9 - 6.5e-06 26.3 0.0 9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 SpoVG SoPB_HTH PF18090.1 AAAP01003801.1_12 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Centromere-binding protein HTH domain Resolvase PF00239.21 AAAP01003801.1_13 - 5.7e-38 130.3 0.0 1.1e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 AAAP01003801.1_13 - 3.2e-15 56.4 1.3 6.2e-15 55.5 1.3 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 AAAP01003801.1_13 - 1.1e-09 38.7 0.0 2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Recombinase Ogr_Delta PF04606.12 AAAP01003801.1_13 - 0.49 10.4 2.6 1 9.4 2.6 1.6 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DUF2924 PF11149.8 AAAP01003801.1_14 - 7e-52 175.4 0.0 8e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2924) NMN_transporter PF04973.12 AAAP01003801.1_17 - 0.0046 17.0 5.1 0.0052 16.8 5.1 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter Imp-YgjV PF10688.9 AAAP01003801.1_17 - 0.023 14.5 2.7 0.036 13.9 2.7 1.4 1 1 0 1 1 1 0 Bacterial inner membrane protein PLDc_2 PF13091.6 AAAP01003801.1_18 - 1.2e-25 90.0 0.4 1.4e-25 89.7 0.4 1.1 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 AAAP01003801.1_18 - 9.2e-07 28.7 0.1 7.7e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 FAM83 A-H PLDc PF00614.22 AAAP01003801.1_18 - 0.0013 18.9 0.0 0.0046 17.1 0.0 2.0 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 AAAP01003801.1_18 - 0.03 13.5 0.2 0.068 12.4 0.1 1.5 1 1 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF4864 PF16156.5 AAAP01003801.1_18 - 0.031 15.0 0.1 0.24 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4864) DUF3572 PF12096.8 AAAP01003801.1_19 - 3.7e-25 87.9 0.2 4.2e-25 87.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3572) Peptidase_S24 PF00717.23 AAAP01003801.1_20 - 1.5e-05 24.9 0.1 2.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like DUF3572 PF12096.8 AAAP01003801.1_21 - 0.044 14.0 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) HTH_17 PF12728.7 AAAP01003801.1_22 - 0.00021 21.4 0.3 0.00029 20.9 0.3 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003801.1_22 - 0.04 13.7 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain AAA_24 PF13479.6 AAAP01003801.1_25 - 3.1e-43 147.8 0.0 3.5e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003801.1_25 - 0.00091 19.6 0.1 0.0015 18.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AAAP01003801.1_25 - 0.0021 18.5 0.0 0.0077 16.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003801.1_25 - 0.0021 18.3 0.0 0.0041 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003801.1_25 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AAAP01003801.1_25 - 0.02 15.4 0.0 0.054 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AAAP01003801.1_25 - 0.033 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003801.1_25 - 0.034 14.7 0.1 0.074 13.6 0.1 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 AAAP01003801.1_25 - 0.044 13.9 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 AAAP01003801.1_25 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 AAAP01003801.1_25 - 0.16 11.2 0.0 0.72 9.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain RuvB_N PF05496.12 AAAP01003801.1_25 - 0.18 11.6 0.0 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 AAAP01003801.1_25 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PilZ PF07238.14 AAAP01003802.1_2 - 0.0045 17.3 0.1 0.0084 16.4 0.1 1.4 1 1 0 1 1 1 1 PilZ domain HATPase_c PF02518.26 AAAP01003802.1_3 - 1.5e-24 86.7 0.0 2.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAAP01003802.1_3 - 7.3e-09 35.8 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003802.1_3 - 9.3e-09 35.1 0.0 4.7e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003802.1_3 - 1.4e-08 34.7 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003802.1_3 - 1.2e-07 31.7 0.0 2.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003802.1_3 - 4.7e-06 26.8 0.1 1e-05 25.8 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003802.1_3 - 2.4e-05 24.5 0.0 0.00024 21.3 0.0 2.5 2 0 0 2 2 2 1 PAS fold EamA PF00892.20 AAAP01003802.1_4 - 1.1e-17 64.5 33.3 2.4e-13 50.4 14.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family Rubrerythrin PF02915.17 AAAP01003802.1_5 - 7.4e-14 52.3 0.6 1.8e-06 28.4 0.0 2.0 2 0 0 2 2 2 2 Rubrerythrin Ferritin_2 PF13668.6 AAAP01003802.1_5 - 2e-06 28.1 1.3 4.8e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 Ferritin-like domain Ferritin PF00210.24 AAAP01003802.1_5 - 8.3e-05 22.6 5.0 0.00022 21.2 5.0 1.7 1 1 0 1 1 1 1 Ferritin-like domain DUF2383 PF09537.10 AAAP01003802.1_5 - 0.0034 17.7 1.1 0.018 15.4 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF2383) COQ7 PF03232.13 AAAP01003802.1_5 - 0.032 14.0 0.5 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF305 PF03713.13 AAAP01003802.1_5 - 0.035 14.3 3.1 0.14 12.3 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF305) DUF4861 PF16153.5 AAAP01003802.1_5 - 0.044 12.8 0.1 0.052 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) FCH PF00611.23 AAAP01003802.1_5 - 0.087 13.1 0.0 6.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain HSCB_C PF07743.13 AAAP01003802.1_5 - 0.28 11.7 4.4 0.4 11.2 0.8 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain GerE PF00196.19 AAAP01003802.1_6 - 3.9e-19 67.9 0.0 6.3e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAAP01003802.1_6 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAAP01003802.1_6 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 AAAP01003802.1_6 - 0.00028 20.9 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003802.1_6 - 0.00037 20.0 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AAAP01003802.1_6 - 0.0048 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 AAAP01003802.1_6 - 0.062 13.1 0.0 0.39 10.5 0.0 2.2 1 1 0 1 1 1 0 HTH DNA binding domain Hit1_C PF18268.1 AAAP01003802.1_6 - 0.2 11.8 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal CHAP PF05257.16 AAAP01003802.1_7 - 7.8e-09 36.0 0.7 7.8e-09 36.0 0.7 1.8 1 1 1 2 2 2 1 CHAP domain NMT1_3 PF16868.5 AAAP01003802.1_8 - 2.1e-56 191.5 0.0 2.6e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01003802.1_8 - 1.4e-08 35.0 0.1 3.1e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AAAP01003802.1_8 - 6.1e-05 22.7 0.1 0.00039 20.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 AAAP01003802.1_8 - 0.00052 19.8 0.3 0.027 14.2 0.3 2.1 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AAAP01003802.1_8 - 0.0079 15.7 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 PBP_like_2 PF12849.7 AAAP01003802.1_8 - 0.067 12.8 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 PBP superfamily domain Cytochrom_C PF00034.21 AAAP01003802.1_10 - 9.3e-09 36.3 0.0 1.3e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003802.1_10 - 0.00024 21.3 2.7 0.00094 19.5 2.7 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DEAD PF00270.29 AAAP01003802.1_11 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AAAP01003802.1_11 - 0.0018 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 AAAP01003802.1_11 - 0.023 14.7 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 AAAP01003802.1_11 - 0.027 14.8 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AAAP01003802.1_11 - 0.051 13.6 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 AAAP01003802.1_11 - 0.074 12.8 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain HrpB_C PF08482.10 AAAP01003802.1_12 - 1.3e-52 177.7 0.0 1.9e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal HA2 PF04408.23 AAAP01003802.1_12 - 1.2e-11 44.8 0.2 2.1e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 AAAP01003802.1_12 - 1.4e-11 44.7 0.0 2.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FeS_assembly_P PF01883.19 AAAP01003802.1_14 - 6e-19 68.0 0.9 1.1e-18 67.1 0.4 1.6 1 1 1 2 2 2 1 Iron-sulfur cluster assembly protein HATPase_c PF02518.26 AAAP01003802.1_15 - 1.4e-22 80.3 0.1 1.2e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAAP01003802.1_15 - 2.9e-14 53.5 0.0 9.2e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Cache domain PAS PF00989.25 AAAP01003802.1_15 - 1.6e-13 50.7 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003802.1_15 - 7.2e-13 48.4 0.1 7.2e-13 48.4 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003802.1_15 - 4.5e-09 36.5 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003802.1_15 - 1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003802.1_15 - 7.6e-05 22.6 0.0 0.00038 20.4 0.0 2.2 3 0 0 3 3 3 1 PAS domain HATPase_c_5 PF14501.6 AAAP01003802.1_15 - 0.00036 20.4 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAAP01003802.1_15 - 0.15 12.0 0.1 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF2681 PF10883.8 AAAP01003802.1_15 - 0.2 12.1 2.3 16 6.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Amidohydro_1 PF01979.20 AAAP01003802.1_16 - 3.3e-21 76.0 0.0 1.8e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003802.1_16 - 3.1e-09 36.8 1.1 1.3e-08 34.7 1.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family SBP_bac_11 PF13531.6 AAAP01003803.1_1 - 3.2e-45 154.7 1.2 4.2e-45 154.3 1.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01003803.1_1 - 1.8e-13 51.1 5.0 2.5e-13 50.7 5.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAAP01003803.1_1 - 6.4e-06 25.8 0.3 1.1e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAAP01003803.1_1 - 0.0029 16.7 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 PBP superfamily domain BPD_transp_1 PF00528.22 AAAP01003803.1_2 - 2.1e-23 83.0 14.7 2.1e-23 83.0 14.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3624 PF12292.8 AAAP01003803.1_2 - 3.4 8.2 5.0 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) BPD_transp_1 PF00528.22 AAAP01003803.1_3 - 1.6e-10 41.0 11.3 1.6e-10 41.0 11.3 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 AAAP01003803.1_3 - 0.25 11.4 0.1 0.25 11.4 0.1 3.1 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) ABC_tran PF00005.27 AAAP01003803.1_4 - 1.6e-34 119.3 0.0 2.3e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003803.1_4 - 1e-08 35.4 0.6 0.00055 19.8 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_3 PF12857.7 AAAP01003803.1_4 - 3.2e-08 33.4 0.4 8.1e-08 32.1 0.4 1.7 1 0 0 1 1 1 1 TOBE-like domain CysA_C_terminal PF17850.1 AAAP01003803.1_4 - 2.3e-07 31.3 4.4 1.5e-06 28.6 1.2 3.0 2 0 0 2 2 2 1 CysA C-terminal regulatory domain SMC_N PF02463.19 AAAP01003803.1_4 - 2.3e-07 30.5 0.0 5.5e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain TOBE PF03459.17 AAAP01003803.1_4 - 4.7e-05 23.6 2.0 9.4e-05 22.6 0.2 2.5 3 0 0 3 3 2 1 TOBE domain AAA_16 PF13191.6 AAAP01003803.1_4 - 6.8e-05 23.3 0.6 0.00012 22.5 0.5 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003803.1_4 - 0.00052 20.3 0.2 0.0059 16.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain TOBE_2 PF08402.10 AAAP01003803.1_4 - 0.00076 19.6 1.1 0.0032 17.6 0.3 2.5 2 0 0 2 2 2 1 TOBE domain AAA_29 PF13555.6 AAAP01003803.1_4 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AAAP01003803.1_4 - 0.003 17.5 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 AAAP01003803.1_4 - 0.0064 16.7 0.1 0.044 14.0 0.1 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DLIC PF05783.11 AAAP01003803.1_4 - 0.011 14.6 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 AAAP01003803.1_4 - 0.011 15.6 0.2 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AAAP01003803.1_4 - 0.013 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01003803.1_4 - 0.016 15.7 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003803.1_4 - 0.017 15.6 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAAP01003803.1_4 - 0.018 13.8 0.2 1.9 7.2 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 AAAP01003803.1_4 - 0.019 15.2 0.1 0.044 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AAAP01003803.1_4 - 0.019 14.9 0.1 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 AAAP01003803.1_4 - 0.029 14.6 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003803.1_4 - 0.042 13.6 0.1 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AAAP01003803.1_4 - 0.042 13.8 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 AAAP01003803.1_4 - 0.045 13.3 0.4 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AAAP01003803.1_4 - 0.051 14.0 0.0 0.24 11.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AAAP01003803.1_4 - 0.058 12.8 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 AAAP01003803.1_4 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 AAAP01003803.1_4 - 0.11 11.9 0.1 14 4.9 0.0 2.1 2 0 0 2 2 2 0 KaiC cobW PF02492.19 AAAP01003803.1_4 - 0.14 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 AAAP01003803.1_4 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase sCache_2 PF17200.4 AAAP01003803.1_5 - 1.3e-20 73.8 0.1 1.5e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003803.1_5 - 2.8e-20 72.7 0.0 3.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Cache domain Cache_3-Cache_2 PF17201.4 AAAP01003803.1_5 - 0.00048 19.5 0.1 0.00048 19.5 0.1 1.2 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain DUF1491 PF07372.12 AAAP01003803.1_5 - 0.098 13.0 0.0 0.15 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) Response_reg PF00072.24 AAAP01003803.1_6 - 6.4e-25 87.5 0.0 7.1e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain ALF PF03752.13 AAAP01003803.1_6 - 0.12 12.4 0.6 3.8 7.6 0.1 2.9 2 1 0 2 2 2 0 Short repeats of unknown function Methyltransf_8 PF05148.15 AAAP01003803.1_6 - 0.16 11.8 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase HATPase_c PF02518.26 AAAP01003803.1_7 - 9.8e-31 106.6 0.1 2.7e-30 105.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003803.1_7 - 4.3e-22 77.9 1.0 5.4e-21 74.4 0.4 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003803.1_7 - 9.4e-09 35.5 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 AAAP01003803.1_7 - 0.025 14.5 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 GHKL domain HATPase_c_2 PF13581.6 AAAP01003803.1_7 - 0.036 14.0 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain sCache_2 PF17200.4 AAAP01003803.1_8 - 0.17 11.7 0.0 0.55 10.1 0.1 1.7 2 0 0 2 2 2 0 Single Cache domain 2 PaaX_C PF08223.11 AAAP01003803.1_9 - 1.3e-34 118.4 0.0 2.1e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain PaaX PF07848.12 AAAP01003803.1_9 - 2.3e-26 91.8 0.2 5.1e-26 90.7 0.2 1.6 1 0 0 1 1 1 1 PaaX-like protein PadR PF03551.14 AAAP01003803.1_9 - 0.045 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Metal_resist PF13801.6 AAAP01003803.1_9 - 0.3 11.3 3.8 0.16 12.2 0.8 2.1 2 0 0 2 2 2 0 Heavy-metal resistance MarR PF01047.22 AAAP01003803.1_10 - 9e-14 51.2 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01003803.1_10 - 1.6e-12 47.1 0.0 3.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01003803.1_10 - 1.1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 AAAP01003803.1_10 - 2e-06 27.8 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.19 AAAP01003803.1_10 - 4.3e-06 26.5 0.0 7.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 AAAP01003803.1_10 - 6.4e-05 22.8 0.1 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003803.1_10 - 7.3e-05 22.3 0.1 0.00013 21.4 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAAP01003803.1_10 - 0.00048 20.0 0.0 0.00095 19.1 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AAAP01003803.1_10 - 0.00067 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_34 PF13601.6 AAAP01003803.1_10 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_29 PF13551.6 AAAP01003803.1_10 - 0.0016 18.5 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix SMC_ScpB PF04079.16 AAAP01003803.1_10 - 0.0016 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB GntR PF00392.21 AAAP01003803.1_10 - 0.0023 17.5 0.1 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TFIIE_alpha PF02002.17 AAAP01003803.1_10 - 0.0044 16.9 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_IclR PF09339.10 AAAP01003803.1_10 - 0.012 15.4 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 AAAP01003803.1_10 - 0.019 15.1 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 AAAP01003803.1_10 - 0.02 14.9 0.4 0.1 12.7 0.0 2.3 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003803.1_10 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix hemP PF10636.9 AAAP01003803.1_10 - 0.029 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP Penicillinase_R PF03965.16 AAAP01003803.1_10 - 0.029 14.7 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor DUF480 PF04337.12 AAAP01003803.1_10 - 0.052 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF480 Rrf2 PF02082.20 AAAP01003803.1_10 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR PF03551.14 AAAP01003803.1_10 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Fer2_2 PF01799.20 AAAP01003803.1_11 - 1.3e-16 60.3 0.1 1.3e-16 60.3 0.1 1.8 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003803.1_11 - 1.6e-09 37.5 1.8 2.3e-08 33.9 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01003803.1_11 - 2.7e-06 27.4 0.1 4.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAAP01003803.1_11 - 0.047 13.8 0.5 0.087 12.9 0.5 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer2_BFD PF04324.15 AAAP01003803.1_11 - 2.6 8.5 10.0 29 5.1 0.3 3.5 2 2 1 3 3 3 0 BFD-like [2Fe-2S] binding domain Ald_Xan_dh_C2 PF02738.18 AAAP01003803.1_12 - 3.6e-151 504.4 5.2 4.3e-151 504.1 5.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01003803.1_12 - 3.6e-32 111.0 0.6 8.1e-32 109.9 0.6 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain RAMA PF18755.1 AAAP01003803.1_12 - 0.044 14.2 0.1 3.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Restriction Enzyme Adenine Methylase Associated FAD_binding_5 PF00941.21 AAAP01003803.1_13 - 3.6e-41 140.7 0.0 5.4e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAAP01003803.1_13 - 1.1e-08 35.2 0.7 2.3e-08 34.1 0.7 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Baculo_p47 PF05112.12 AAAP01003803.1_13 - 0.16 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P47 protein XdhC_C PF13478.6 AAAP01003803.1_14 - 7.3e-37 126.7 0.7 1.4e-36 125.7 0.7 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AAAP01003803.1_14 - 4.8e-21 74.7 2.0 4.8e-21 74.7 2.0 3.2 3 1 0 3 3 3 1 XdhC and CoxI family TrkA_N PF02254.18 AAAP01003803.1_14 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Bac_DNA_binding PF00216.21 AAAP01003803.1_15 - 1.1e-32 112.0 0.1 1.4e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003803.1_15 - 5e-08 33.1 0.0 6.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 AAAP01003803.1_15 - 0.0046 17.1 0.1 0.0077 16.4 0.1 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 AAAP01003803.1_15 - 0.013 15.3 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DUF2267 PF10025.9 AAAP01003803.1_15 - 0.1 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Fibrinogen_BP PF08017.11 AAAP01003803.1_15 - 0.12 10.8 0.1 0.14 10.6 0.1 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein Acyl-CoA_dh_1 PF00441.24 AAAP01003803.1_16 - 8.1e-29 100.8 7.2 2.4e-28 99.2 7.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003803.1_16 - 1.7e-16 60.2 0.0 3.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAAP01003803.1_16 - 6.3e-14 52.6 0.2 2e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01003803.1_16 - 5.1e-08 33.3 2.0 5.1e-08 33.3 2.0 2.8 4 1 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_C PF12806.7 AAAP01003803.1_16 - 7.3e-07 29.4 3.6 2.1e-06 27.9 3.6 1.7 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like AMP-binding PF00501.28 AAAP01003803.1_17 - 7.4e-24 84.1 0.0 1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SBP_bac_3 PF00497.20 AAAP01003804.1_1 - 4.8e-08 32.7 0.0 1.6e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.6 AAAP01003804.1_1 - 0.016 15.0 0.2 0.22 11.3 0.0 2.5 1 1 2 3 3 3 0 Bacterial extracellular solute-binding protein Cadherin_5 PF17892.1 AAAP01003804.1_3 - 1.1e-93 307.5 66.6 1.8e-33 114.4 6.6 7.0 7 0 0 7 7 7 4 Cadherin-like domain Big_9 PF17963.1 AAAP01003804.1_3 - 1.6e-46 157.0 43.0 1.5e-18 67.3 9.1 10.8 6 3 3 9 9 9 4 Bacterial Ig domain Cadherin_4 PF17803.1 AAAP01003804.1_3 - 4.6e-30 104.0 41.4 7.3e-13 48.9 9.0 9.7 5 1 1 6 6 6 3 Bacterial cadherin-like domain GldM_C PF12080.8 AAAP01003804.1_3 - 1.4e-05 25.4 0.3 2.3 8.4 0.0 4.4 2 1 2 4 4 4 2 GldM C-terminal domain polyprenyl_synt PF00348.17 AAAP01003804.1_4 - 4.9e-72 242.1 0.0 6.1e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MTS PF05175.14 AAAP01003804.1_5 - 4.3e-12 45.9 0.0 3.5e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 AAAP01003804.1_5 - 1e-05 25.0 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 AAAP01003804.1_5 - 3.1e-05 24.6 0.1 6.9e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003804.1_5 - 0.00022 21.1 0.0 0.00051 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003804.1_5 - 0.0054 16.5 0.0 0.0089 15.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAAP01003804.1_5 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 AAAP01003804.1_5 - 0.013 16.1 0.2 0.077 13.7 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 AAAP01003804.1_5 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 AAAP01003804.1_5 - 0.13 13.0 0.1 2 9.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain COX3 PF00510.18 AAAP01003804.1_7 - 4.6e-88 295.4 22.3 5.2e-88 295.2 22.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III DUF2530 PF10745.9 AAAP01003804.1_7 - 0.02 15.1 0.5 0.02 15.1 0.5 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2530) DUF202 PF02656.15 AAAP01003804.1_7 - 0.18 12.3 0.4 0.18 12.3 0.4 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF202) DUF2975 PF11188.8 AAAP01003804.1_7 - 7.8 6.4 8.0 0.19 11.6 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) CtaG_Cox11 PF04442.14 AAAP01003804.1_8 - 4.5e-54 182.6 0.0 5.2e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 BrnA_antitoxin PF14384.6 AAAP01003804.1_8 - 0.077 13.5 0.0 0.9 10.1 0.0 2.2 1 1 1 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system COX1 PF00115.20 AAAP01003804.1_9 - 2.2e-156 521.1 72.3 2.7e-156 520.8 72.3 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 AAAP01003804.1_10 - 2.5e-51 172.6 0.0 3.5e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 AAAP01003804.1_10 - 2.3e-24 85.4 0.3 3.4e-24 84.8 0.3 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Cupredoxin_1 PF13473.6 AAAP01003804.1_10 - 0.0016 18.5 0.0 0.0045 17.1 0.0 1.8 1 1 1 2 2 2 1 Cupredoxin-like domain MFS_2 PF13347.6 AAAP01003804.1_10 - 0.04 12.5 0.7 0.054 12.1 0.7 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein NPCC PF08058.11 AAAP01003804.1_10 - 0.16 12.0 0.2 0.26 11.3 0.2 1.2 1 0 0 1 1 1 0 Nuclear pore complex component DUF2070 PF09843.9 AAAP01003804.1_10 - 0.26 9.5 0.6 0.36 9.1 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gemini_mov PF01708.16 AAAP01003804.1_10 - 0.68 9.7 3.1 1.8 8.4 0.1 2.2 1 1 1 2 2 2 0 Geminivirus putative movement protein Rhodanese PF00581.20 AAAP01003804.1_12 - 3.2e-11 43.7 0.0 5.7e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Cytochrome_CBB3 PF13442.6 AAAP01003804.1_13 - 0.0038 17.5 0.0 0.0052 17.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III FCSD-flav_bind PF09242.11 AAAP01003804.1_14 - 2.4e-26 91.9 0.1 6.3e-26 90.5 0.1 1.8 1 0 0 1 1 1 1 Flavocytochrome c sulphide dehydrogenase, flavin-binding Pyr_redox_2 PF07992.14 AAAP01003804.1_14 - 1.3e-11 44.3 0.1 1.2e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003804.1_14 - 3e-05 24.2 5.2 0.00071 19.8 0.0 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AAAP01003804.1_14 - 3.6e-05 23.8 0.1 0.044 13.8 0.1 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 AAAP01003804.1_14 - 0.00016 21.0 0.0 0.00034 19.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 AAAP01003804.1_14 - 0.00018 21.2 1.4 0.0021 17.7 1.5 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAAP01003804.1_14 - 0.0023 16.8 0.1 0.0036 16.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 AAAP01003804.1_14 - 0.014 14.5 0.0 0.037 13.1 0.0 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AAAP01003804.1_14 - 0.022 14.0 3.8 0.53 9.5 1.7 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_6 PF12697.7 AAAP01003804.1_14 - 0.12 13.0 7.4 0.019 15.6 2.6 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase family UPF0052 PF01933.18 AAAP01003804.1_14 - 0.12 11.6 0.3 7 5.8 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 zf-dskA_traR PF01258.17 AAAP01003804.1_16 - 2.1e-11 43.5 1.4 2.1e-11 43.5 1.4 1.6 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 AAAP01003804.1_16 - 0.0059 16.6 1.9 0.008 16.2 1.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon RNA_POL_M_15KD PF02150.16 AAAP01003804.1_16 - 0.054 13.4 1.0 0.083 12.8 1.0 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF2039 PF10217.9 AAAP01003804.1_16 - 0.1 13.0 2.1 4.6 7.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) FGase PF05013.12 AAAP01003804.1_18 - 5.2e-70 236.0 0.1 6.9e-70 235.6 0.1 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase Acetyltransf_4 PF13420.7 AAAP01003804.1_19 - 3.8e-27 95.3 0.0 4.4e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003804.1_19 - 2.9e-12 46.8 0.1 3.7e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AAAP01003804.1_19 - 2.8e-06 28.0 0.0 3.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003804.1_19 - 1.4e-05 25.0 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01003804.1_19 - 3.4e-05 24.2 0.1 5.9e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003804.1_19 - 0.00017 21.5 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 AAAP01003804.1_19 - 0.0021 18.2 0.5 0.003 17.7 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AAAP01003804.1_19 - 0.19 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF3265 PF11665.8 AAAP01003804.1_19 - 0.75 10.1 4.2 0.29 11.4 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3265) SLT PF01464.20 AAAP01003804.1_20 - 8e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain SNARE_assoc PF09335.11 AAAP01003804.1_21 - 9.4e-13 48.7 6.6 9.4e-13 48.7 6.6 2.2 1 1 2 3 3 3 1 SNARE associated Golgi protein Mntp PF02659.15 AAAP01003804.1_21 - 0.0016 18.2 1.3 0.0016 18.2 1.3 1.7 2 0 0 2 2 2 1 Putative manganese efflux pump ATPase_gene1 PF09527.10 AAAP01003804.1_21 - 1.6 9.0 13.0 3 8.1 8.7 3.2 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ATP-grasp PF02222.22 AAAP01003804.1_22 - 2.6e-50 170.3 0.0 3.6e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AAAP01003804.1_22 - 1.2e-15 56.9 0.0 2.2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain PALP PF00291.25 AAAP01003804.1_22 - 0.0014 18.1 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 AAAP01003804.1_22 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 AAAP01003804.1_22 - 0.014 14.5 0.7 0.021 13.9 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GARS_A PF01071.19 AAAP01003804.1_22 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 AAAP01003804.1_22 - 0.036 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain AlaDh_PNT_C PF01262.21 AAAP01003804.1_22 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 AAAP01003804.1_22 - 0.093 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01003804.1_22 - 0.11 13.1 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAAP01003804.1_22 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AIRC PF00731.20 AAAP01003804.1_23 - 4.6e-60 201.5 1.4 5.2e-60 201.3 1.4 1.0 1 0 0 1 1 1 1 AIR carboxylase GGDEF PF00990.21 AAAP01003804.1_24 - 6.2e-14 52.1 0.0 8.4e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GerE PF00196.19 AAAP01003804.1_25 - 4.3e-12 45.4 0.6 5.7e-12 45.0 0.6 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Methyltransf_5 PF01795.19 AAAP01003804.1_25 - 0.22 11.0 0.6 0.28 10.7 0.6 1.1 1 0 0 1 1 1 0 MraW methylase family SQS_PSY PF00494.19 AAAP01003805.1_1 - 9.8e-33 113.8 2.2 1.1e-32 113.6 2.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 AAAP01003805.1_3 - 5.6e-18 65.5 0.0 9.9e-18 64.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase PSP PF04046.16 AAAP01003805.1_3 - 2.1 8.3 5.8 0.8 9.6 0.4 2.8 4 0 0 4 4 4 0 PSP Sod_Fe_C PF02777.18 AAAP01003805.1_4 - 1.4e-35 121.5 0.3 6.6e-35 119.4 0.0 2.0 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AAAP01003805.1_4 - 7.4e-33 112.9 0.8 1.1e-32 112.3 0.8 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF498 PF04430.14 AAAP01003805.1_5 - 2.6e-33 114.4 0.0 2.9e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SecD_SecF PF02355.16 AAAP01003805.1_6 - 2.8e-53 180.1 10.1 3.2e-53 179.9 10.1 1.0 1 0 0 1 1 1 1 Protein export membrane protein ACR_tran PF00873.19 AAAP01003805.1_6 - 0.0019 16.0 3.7 0.0023 15.7 3.7 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF2207 PF09972.9 AAAP01003805.1_6 - 0.16 10.7 1.3 0.18 10.6 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SecD_SecF PF02355.16 AAAP01003805.1_7 - 2.6e-16 59.6 7.3 4.9e-16 58.7 7.3 1.4 1 0 0 1 1 1 1 Protein export membrane protein SecD-TM1 PF13721.6 AAAP01003805.1_7 - 3.6e-08 33.8 1.5 0.00067 20.1 0.1 3.0 3 0 0 3 3 3 2 SecD export protein N-terminal TM region MMPL PF03176.15 AAAP01003805.1_7 - 5.7e-06 25.5 19.5 1.1e-05 24.6 19.5 1.4 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 AAAP01003805.1_7 - 2.4e-05 23.6 0.0 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif Claudin_2 PF13903.6 AAAP01003805.1_7 - 0.045 13.5 2.2 0.091 12.5 2.2 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ACR_tran PF00873.19 AAAP01003805.1_7 - 0.27 8.9 11.8 0.38 8.3 11.8 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family YajC PF02699.15 AAAP01003805.1_8 - 4.1e-29 100.3 0.9 4.9e-29 100.0 0.9 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 AAAP01003805.1_8 - 0.014 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) YMF19 PF02326.15 AAAP01003805.1_8 - 0.076 13.8 0.1 0.14 12.9 0.1 1.4 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF815 PF05673.13 AAAP01003805.1_9 - 1.2e-102 342.4 0.0 1.4e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 AAAP01003805.1_9 - 5.7e-09 36.6 0.4 2.5e-07 31.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 AAAP01003805.1_9 - 0.0006 20.2 0.0 0.002 18.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AAAP01003805.1_9 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AAAP01003805.1_9 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 AAAP01003805.1_9 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01003805.1_9 - 0.067 12.7 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 AAAP01003805.1_9 - 0.076 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AAAP01003805.1_9 - 0.21 11.6 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01003805.1_9 - 0.23 11.8 0.0 0.47 10.9 0.0 1.5 1 1 0 1 1 1 0 RNA helicase Protoglobin PF11563.8 AAAP01003805.1_10 - 1.1e-35 122.9 0.6 1.1e-34 119.6 0.0 2.7 3 0 0 3 3 3 1 Protoglobin MCPsignal PF00015.21 AAAP01003805.1_10 - 1.1e-26 93.6 34.7 7.5e-25 87.7 19.6 3.0 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DHR10 PF18595.1 AAAP01003805.1_10 - 0.00064 19.8 3.8 0.00064 19.8 3.8 2.6 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain DUF948 PF06103.11 AAAP01003805.1_10 - 0.0033 17.6 25.7 0.29 11.4 3.1 4.7 2 2 2 4 4 4 3 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003805.1_10 - 0.029 14.4 12.2 0.035 14.2 2.2 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) MutS_III PF05192.18 AAAP01003805.1_10 - 0.033 14.4 4.9 0.84 9.8 4.9 2.5 1 1 0 1 1 1 0 MutS domain III Syntaxin_2 PF14523.6 AAAP01003805.1_10 - 0.077 13.4 5.1 2.7 8.4 0.6 3.5 2 2 0 2 2 2 0 Syntaxin-like protein GPS2_interact PF15784.5 AAAP01003805.1_10 - 0.088 13.3 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain V_ATPase_I PF01496.19 AAAP01003805.1_10 - 0.098 10.6 6.4 0.14 10.1 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipoprotein_7 PF01540.16 AAAP01003805.1_10 - 0.14 11.5 3.2 0.09 12.1 0.3 1.8 1 1 1 2 2 2 0 Adhesin lipoprotein Potyvirid-P3 PF13608.6 AAAP01003805.1_10 - 0.18 10.8 2.0 0.21 10.6 0.6 1.7 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein Fib_alpha PF08702.10 AAAP01003805.1_10 - 1.1 9.4 4.9 0.57 10.4 0.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dad2 PF08654.10 AAAP01003805.1_10 - 5.9 7.4 12.4 9.3 6.7 1.4 3.5 1 1 2 3 3 3 0 DASH complex subunit Dad2 Sec34 PF04136.15 AAAP01003805.1_10 - 9.4 6.1 6.0 8.3 6.3 0.3 2.8 2 1 1 3 3 3 0 Sec34-like family Peptidase_M23 PF01551.22 AAAP01003805.1_11 - 3.4e-29 100.9 0.1 7.3e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M23 LysM PF01476.20 AAAP01003805.1_11 - 6.9e-27 93.3 0.0 4.4e-13 49.1 0.0 2.6 2 0 0 2 2 2 2 LysM domain Biotin_lipoyl_2 PF13533.6 AAAP01003805.1_11 - 0.0017 18.1 0.0 0.019 14.8 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 AAAP01003805.1_11 - 0.026 14.5 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF2917 PF11142.8 AAAP01003805.1_11 - 0.031 13.7 0.2 8 5.9 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2917) Biotin_lipoyl PF00364.22 AAAP01003805.1_11 - 0.11 12.3 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Biotin-requiring enzyme PCMT PF01135.19 AAAP01003805.1_12 - 7.1e-59 199.1 0.0 8.7e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AAAP01003805.1_12 - 8e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003805.1_12 - 2.5e-06 28.1 0.0 4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AAAP01003805.1_12 - 1e-05 24.8 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 AAAP01003805.1_12 - 3.9e-05 24.2 0.0 9.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AAAP01003805.1_12 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 AAAP01003805.1_12 - 0.016 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 AAAP01003805.1_12 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.10 AAAP01003805.1_12 - 0.023 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 AAAP01003805.1_12 - 0.046 13.3 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF938 PF06080.12 AAAP01003805.1_12 - 0.065 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 AAAP01003805.1_12 - 0.21 11.4 0.0 0.35 10.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain SurE PF01975.17 AAAP01003805.1_13 - 1.5e-59 201.1 0.0 1.8e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE tRNA-synt_2b PF00587.25 AAAP01003805.1_14 - 8.6e-40 136.6 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AAAP01003805.1_14 - 6.7e-29 100.3 0.1 1.1e-28 99.6 0.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 AAAP01003805.1_14 - 0.068 13.0 0.7 0.13 12.1 0.2 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 TatC PF00902.18 AAAP01003805.1_15 - 1.5e-67 227.4 14.8 1.5e-67 227.4 14.8 1.3 2 0 0 2 2 2 1 Sec-independent protein translocase protein (TatC) MttA_Hcf106 PF02416.16 AAAP01003805.1_16 - 1.8e-05 24.0 0.1 2.6e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family cNMP_binding PF00027.29 AAAP01003806.1_1 - 6.4e-18 64.6 0.0 1.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GGDEF PF00990.21 AAAP01003806.1_2 - 7.7e-46 155.8 0.2 1.3e-45 155.0 0.2 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain cNMP_binding PF00027.29 AAAP01003806.1_2 - 3.8e-20 71.7 0.0 2.4e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain PAS_9 PF13426.7 AAAP01003806.1_2 - 1.9e-14 53.7 0.0 3.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003806.1_2 - 2.5e-14 53.2 0.0 4.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003806.1_2 - 1.4e-11 44.6 0.0 3.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003806.1_2 - 1.8e-09 37.7 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003806.1_2 - 1.1e-05 25.3 0.0 4.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 AAAP01003806.1_2 - 0.0039 17.4 2.1 0.0086 16.3 0.2 2.5 2 1 1 3 3 3 1 GGDEF-like domain PAS_12 PF18095.1 AAAP01003806.1_2 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain DUF1269 PF06897.12 AAAP01003806.1_3 - 0.038 14.3 0.1 0.042 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Med3 PF11593.8 AAAP01003806.1_3 - 0.26 10.4 13.4 0.28 10.3 13.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hydrolase_4 PF12146.8 AAAP01003806.1_4 - 3.8e-07 29.6 0.3 0.0003 20.2 0.2 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003806.1_4 - 3.4e-05 23.6 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 AAAP01003806.1_4 - 0.00042 20.0 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 AAAP01003806.1_4 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.25 AAAP01003806.1_4 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.16 AAAP01003806.1_4 - 0.0044 16.9 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 AAAP01003806.1_4 - 0.013 14.2 1.1 0.018 13.7 1.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 AAAP01003806.1_4 - 0.016 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 AAAP01003806.1_4 - 0.039 13.9 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 AAAP01003806.1_4 - 0.061 12.8 0.2 0.16 11.4 0.2 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 AAAP01003806.1_4 - 0.075 12.5 4.9 0.14 11.6 4.9 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF2974 PF11187.8 AAAP01003806.1_4 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.11 AAAP01003806.1_4 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PGAP1 PF07819.13 AAAP01003806.1_4 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein COX6C PF02937.15 AAAP01003806.1_4 - 0.23 11.6 0.3 0.58 10.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Abhydrolase_6 PF12697.7 AAAP01003806.1_4 - 0.34 11.5 22.1 0.015 16.0 13.1 2.4 1 1 1 2 2 1 0 Alpha/beta hydrolase family Autotransporter PF03797.19 AAAP01003806.1_5 - 1.4e-12 47.8 24.4 2.2e-12 47.2 24.4 1.3 1 0 0 1 1 1 1 Autotransporter beta-domain PqqD PF05402.12 AAAP01003806.1_6 - 1e-08 35.3 0.1 2.3e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) ATPgrasp_Ter PF15632.6 AAAP01003806.1_7 - 1.8e-07 30.9 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 AAAP01003806.1_7 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AAAP01003806.1_7 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Orn_Arg_deC_N PF02784.16 AAAP01003806.1_8 - 3.5e-33 115.0 0.0 4.9e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAAP01003806.1_8 - 6.9e-13 48.7 0.0 2e-12 47.2 0.0 1.5 1 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAAP01003806.1_8 - 3.2e-12 46.6 0.0 5e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Acetyltransf_3 PF13302.7 AAAP01003806.1_9 - 2e-20 73.8 0.0 2.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003806.1_9 - 2.2e-09 37.6 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAAP01003806.1_9 - 3.6e-06 26.7 0.0 7.6e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAAP01003806.1_9 - 0.037 14.2 0.0 0.05 13.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UT PF03253.14 AAAP01003806.1_10 - 2.3e-24 86.1 36.5 3e-24 85.7 36.5 1.2 1 0 0 1 1 1 1 Urea transporter Peptidase_M23 PF01551.22 AAAP01003806.1_10 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 Asn_synthase PF00733.21 AAAP01003806.1_11 - 1e-65 222.8 0.1 7.5e-43 147.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 AAAP01003806.1_11 - 7e-33 113.2 0.0 1e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003806.1_11 - 1.1e-27 96.9 0.0 1.8e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAAP01003806.1_11 - 0.00025 20.3 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD synthase UT PF03253.14 AAAP01003806.1_12 - 2.4e-14 53.2 5.3 2.4e-14 53.2 5.3 2.5 2 1 0 2 2 1 1 Urea transporter TPR_2 PF07719.17 AAAP01003806.1_12 - 6e-12 44.7 0.2 0.033 14.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003806.1_12 - 1.2e-09 38.5 0.2 0.00012 22.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003806.1_12 - 1.4e-08 34.8 8.3 0.14 13.1 0.1 4.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003806.1_12 - 2.2e-08 34.6 15.2 0.0002 21.9 0.8 3.3 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003806.1_12 - 4.5e-07 30.1 4.5 0.015 15.6 0.1 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003806.1_12 - 6.8e-07 28.8 0.0 0.22 11.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003806.1_12 - 0.00032 20.3 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 AAAP01003806.1_12 - 0.01 15.7 2.3 0.6 10.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003806.1_12 - 0.026 14.5 1.0 27 5.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003806.1_12 - 0.064 13.7 0.0 6.9 7.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003806.1_12 - 0.084 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AAAP01003806.1_12 - 0.1 12.9 0.0 42 4.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003806.1_12 - 0.12 13.1 17.7 7.2 7.5 2.3 5.3 5 0 0 5 5 3 0 Tetratricopeptide repeat HATPase_c PF02518.26 AAAP01003806.1_13 - 1e-17 64.7 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003806.1_13 - 9.9e-12 44.7 1.2 1.8e-11 43.9 0.3 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAAP01003806.1_14 - 4.5e-28 97.7 0.0 6.3e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003806.1_14 - 1.4e-20 73.1 0.0 3.2e-20 72.0 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAAP01003806.1_14 - 0.026 14.4 0.5 0.91 9.5 0.0 3.0 2 1 0 2 2 2 0 MarR family Glyco_hydro_25 PF01183.20 AAAP01003806.1_15 - 1.8e-27 96.6 0.0 6.6e-27 94.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 25 DUF2921 PF11145.8 AAAP01003806.1_15 - 0.33 8.7 0.0 0.41 8.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) GGDEF PF00990.21 AAAP01003806.1_16 - 2.1e-48 164.1 0.1 2.8e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AAAP01003806.1_16 - 0.011 16.0 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 GGDEF-like domain PRONE PF03759.13 AAAP01003806.1_16 - 0.017 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) FAD-oxidase_C PF02913.19 AAAP01003806.1_16 - 0.07 12.7 0.1 13 5.4 0.0 2.3 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Phage_integrase PF00589.22 AAAP01003807.1_2 - 1.5e-12 47.7 0.0 2.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 AAAP01003807.1_2 - 1.6e-05 25.1 0.2 3.4e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain TerB PF05099.13 AAAP01003807.1_3 - 2.9e-06 27.3 0.6 2.9e-05 24.0 0.1 2.0 1 1 1 2 2 2 2 Tellurite resistance protein TerB EAL PF00563.20 AAAP01003807.1_4 - 4.2e-72 242.5 0.0 7.5e-72 241.7 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003807.1_4 - 3.3e-51 173.2 0.6 6.2e-51 172.3 0.1 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AAAP01003807.1_4 - 2.4e-30 105.0 0.0 3e-15 56.4 0.0 4.7 3 1 0 3 3 3 3 PAS fold PAS PF00989.25 AAAP01003807.1_4 - 8e-21 74.2 0.0 1.2e-07 31.7 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01003807.1_4 - 9.9e-18 64.3 0.0 2.4e-08 34.2 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.7 AAAP01003807.1_4 - 4.6e-09 36.1 0.2 0.00018 21.5 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS_7 PF12860.7 AAAP01003807.1_4 - 1.1e-07 31.9 0.0 0.35 11.1 0.0 4.1 3 1 0 3 3 3 2 PAS fold DUF3422 PF11902.8 AAAP01003807.1_5 - 1e-166 555.2 0.1 1.2e-166 555.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) DnaG_DnaB_bind PF08278.11 AAAP01003807.1_5 - 0.022 15.4 2.2 0.027 15.1 0.5 2.0 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding ABC_tran_CTD PF16326.5 AAAP01003807.1_5 - 0.54 10.6 3.0 0.32 11.3 0.3 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain PmbA_TldD PF01523.16 AAAP01003807.1_6 - 9.2e-67 225.8 0.2 2e-66 224.7 0.0 1.6 2 0 0 2 2 2 1 Putative modulator of DNA gyrase Glucosaminidase PF01832.20 AAAP01003807.1_7 - 8.5e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Nfu_N PF08712.11 AAAP01003807.1_8 - 1.2e-31 108.6 0.0 1.8e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 AAAP01003807.1_8 - 2.1e-29 101.4 0.0 3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain GARS_N PF02844.15 AAAP01003807.1_8 - 0.098 13.4 0.0 0.22 12.3 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Usp PF00582.26 AAAP01003807.1_9 - 4e-14 53.3 0.0 4.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family DNA_photolyase PF00875.18 AAAP01003807.1_9 - 0.04 13.9 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 DNA photolyase DUF3088 PF11287.8 AAAP01003807.1_9 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Alph_Pro_TM PF09608.10 AAAP01003807.1_10 - 1.8e-80 270.0 0.0 2.1e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) KOW PF00467.29 AAAP01003807.1_10 - 0.0026 17.7 0.9 0.0052 16.7 0.9 1.6 1 0 0 1 1 1 1 KOW motif NIL PF09383.10 AAAP01003807.1_10 - 0.12 12.3 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 NIL domain TcfC PF16967.5 AAAP01003807.1_10 - 0.16 11.5 0.1 0.35 10.4 0.1 1.5 1 0 0 1 1 1 0 E-set like domain TauE PF01925.19 AAAP01003807.1_11 - 3.5e-51 174.1 41.9 4.6e-51 173.7 41.9 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF2333 PF10095.9 AAAP01003807.1_12 - 1.5e-08 34.1 0.1 0.0001 21.5 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2333) DUF1818 PF08848.11 AAAP01003807.1_12 - 0.082 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) SepF PF04472.12 AAAP01003807.1_12 - 0.2 12.0 0.2 4.5 7.6 0.0 2.4 3 0 0 3 3 3 0 Cell division protein SepF Relaxase PF03432.14 AAAP01003808.1_1 - 7.3e-10 38.9 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain LPD7 PF18821.1 AAAP01003808.1_1 - 3.1e-09 36.8 0.0 7.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 7 RHH_1 PF01402.21 AAAP01003808.1_2 - 0.2 11.7 1.5 0.89 9.6 0.1 2.6 3 1 0 3 3 3 0 Ribbon-helix-helix protein, copG family HTH_18 PF12833.7 AAAP01003808.1_3 - 1.5e-22 79.6 0.2 1.8e-21 76.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AAAP01003808.1_3 - 2.8e-12 46.4 0.1 1.2e-06 28.4 0.0 3.2 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_11 PF08279.12 AAAP01003808.1_3 - 0.12 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain DUF4347 PF14252.6 AAAP01003808.1_4 - 8.4e-64 214.4 9.6 7.9e-36 123.4 0.4 3.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4347) Big_9 PF17963.1 AAAP01003808.1_4 - 1.2e-07 32.4 24.0 1.9e-06 28.5 11.1 33.4 15 8 14 29 29 29 3 Bacterial Ig domain Cadherin_3 PF16184.5 AAAP01003808.1_4 - 1.6e-06 28.1 4.6 0.0014 18.7 0.1 5.3 5 0 0 5 5 5 1 Cadherin-like Cadherin_5 PF17892.1 AAAP01003808.1_4 - 2.1e-06 27.6 3.7 2.1e-06 27.6 3.7 15.4 19 0 0 19 19 19 1 Cadherin-like domain Cadherin PF00028.17 AAAP01003808.1_4 - 0.0032 17.9 6.8 0.26 11.7 0.2 4.7 5 0 0 5 5 5 2 Cadherin domain ADH_zinc_N PF00107.26 AAAP01003809.1_1 - 1.1e-29 103.1 0.7 1.9e-29 102.3 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01003809.1_1 - 1.5e-28 100.5 0.0 3.1e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003809.1_1 - 1.1e-09 38.2 0.0 1e-07 31.8 0.0 2.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AAAP01003809.1_1 - 0.01 15.2 0.6 0.018 14.4 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 AAAP01003809.1_1 - 0.044 13.2 0.8 0.08 12.4 0.8 1.4 1 0 0 1 1 1 0 short chain dehydrogenase EIIA-man PF03610.16 AAAP01003809.1_1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component MccV PF17508.2 AAAP01003809.1_1 - 0.64 10.6 4.3 0.9 10.1 0.1 2.5 2 0 0 2 2 2 0 Microcin V bacteriocin DUF1192 PF06698.11 AAAP01003809.1_2 - 1.8e-22 79.2 1.9 2e-22 79.0 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Spc7 PF08317.11 AAAP01003809.1_2 - 0.096 11.6 0.1 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein adh_short_C2 PF13561.6 AAAP01003809.1_3 - 8.7e-54 182.5 2.5 1.7e-53 181.6 2.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003809.1_3 - 3.5e-52 176.7 0.7 4.3e-52 176.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003809.1_3 - 7.5e-08 32.5 1.0 1.4e-07 31.6 1.0 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 AAAP01003809.1_3 - 0.037 14.0 1.1 0.12 12.4 1.1 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 AAAP01003809.1_3 - 0.11 12.6 1.1 0.59 10.2 1.1 2.1 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 4HBT_2 PF13279.6 AAAP01003809.1_4 - 3.5e-08 34.0 0.0 5.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAAP01003809.1_4 - 6.4e-08 32.8 0.2 1.5e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 AAAP01003809.1_4 - 1.4e-06 27.8 0.0 7.5e-05 22.1 0.1 2.0 2 0 0 2 2 2 2 Acyl-ACP thioesterase Hexapep PF00132.24 AAAP01003809.1_5 - 9.3e-14 50.5 6.9 1.5e-05 24.5 0.1 3.7 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003809.1_5 - 0.00012 21.7 11.6 0.02 14.7 4.9 3.5 2 2 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AAAP01003809.1_5 - 0.035 13.1 0.0 0.67 8.8 0.0 2.0 1 1 1 2 2 2 0 L-fucokinase Ni_hydr_CYTB PF01292.20 AAAP01003809.1_6 - 2.8e-18 66.2 17.7 2.8e-18 66.2 17.7 2.0 2 1 0 2 2 2 1 Prokaryotic cytochrome b561 PsbW PF07123.12 AAAP01003809.1_6 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Fer4_7 PF12838.7 AAAP01003809.1_8 - 2.6e-13 50.3 19.9 4.5e-08 33.6 0.5 2.8 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.6 AAAP01003809.1_8 - 4e-13 49.3 16.7 1.9e-10 40.8 6.6 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003809.1_8 - 8.3e-10 38.7 24.6 1.5e-06 28.3 1.8 3.2 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003809.1_8 - 7.5e-09 35.6 30.8 1.5e-06 28.2 5.2 3.3 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003809.1_8 - 8.7e-09 34.8 37.9 4.3e-08 32.6 1.4 5.6 6 0 0 6 6 6 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003809.1_8 - 2e-07 30.8 11.1 6.7e-07 29.1 1.2 4.3 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003809.1_8 - 7.7e-07 28.8 29.7 0.00013 21.9 0.7 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003809.1_8 - 1.1e-05 26.0 40.5 0.0047 17.8 3.8 4.6 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003809.1_8 - 5.2e-05 23.3 28.4 0.021 14.9 14.3 3.4 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003809.1_8 - 0.0031 17.9 30.5 0.0068 16.8 2.1 4.0 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003809.1_8 - 0.075 13.5 29.5 0.41 11.1 7.1 3.8 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003809.1_8 - 0.21 12.1 29.8 0.35 11.5 1.8 4.4 3 1 1 5 5 5 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003809.1_8 - 0.44 11.5 28.5 1.2 10.1 6.8 4.2 3 1 1 4 4 4 0 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AAAP01003809.1_8 - 0.54 11.0 0.3 0.54 11.0 0.3 4.2 3 2 0 3 3 3 0 4Fe-4S single cluster domain Molybdopterin PF00384.22 AAAP01003809.1_9 - 9.6e-62 209.3 0.2 1.2e-61 209.0 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003809.1_9 - 9.8e-19 67.4 0.0 2.3e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003809.1_9 - 1.7e-10 40.7 1.0 5e-10 39.2 0.6 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Nitrate_red_del PF02613.15 AAAP01003809.1_11 - 4e-27 94.9 0.0 5.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit V4R PF02830.18 AAAP01003809.1_11 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 V4R domain DUF3306 PF11748.8 AAAP01003809.1_12 - 1.1e-20 74.7 0.7 8.4e-16 58.9 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3306) DUF3305 PF11749.8 AAAP01003809.1_13 - 2.9e-36 124.7 0.0 4.9e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3305) NTP_transf_3 PF12804.7 AAAP01003809.1_13 - 1.7e-33 116.3 0.9 1.7e-33 116.3 0.9 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003809.1_13 - 0.021 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FdhD-NarQ PF02634.15 AAAP01003809.1_14 - 7.6e-71 238.5 0.0 8.8e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family EPSP_synthase PF00275.20 AAAP01003809.1_14 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Fer4_16 PF13484.6 AAAP01003809.1_15 - 2.5e-07 31.5 3.4 0.0043 18.0 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 AAAP01003809.1_15 - 2.6e-06 27.0 7.4 0.003 17.3 1.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003809.1_15 - 8.4e-05 23.1 7.4 0.0013 19.3 7.1 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003809.1_15 - 0.0021 18.2 3.1 0.0021 18.2 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003809.1_15 - 0.0023 17.9 15.1 0.0096 16.0 1.4 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003809.1_15 - 0.0026 17.8 4.3 0.0062 16.6 4.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003809.1_15 - 0.0062 16.6 7.0 0.0062 16.6 7.0 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003809.1_15 - 2.1 8.8 7.0 12 6.4 0.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003809.1_15 - 2.8 8.2 16.1 0.16 12.2 1.2 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003809.1_16 - 3.1e-09 37.3 11.9 0.00047 20.7 0.2 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003809.1_16 - 1.1e-08 34.5 23.2 1.4e-06 27.9 1.3 3.5 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003809.1_16 - 4.7e-07 29.5 21.8 0.0002 21.2 2.6 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003809.1_16 - 5.6e-07 29.4 12.1 1.7e-06 27.9 1.9 3.6 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003809.1_16 - 1.4e-06 28.3 10.4 1.4e-06 28.3 10.4 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003809.1_16 - 9.9e-06 25.6 18.8 0.00045 20.3 13.2 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003809.1_16 - 2.2e-05 24.5 11.3 2.2e-05 24.5 11.3 2.8 2 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003809.1_16 - 3e-05 24.4 15.2 0.012 16.0 4.9 2.9 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003809.1_16 - 6.6e-05 23.8 18.2 0.0039 18.1 1.8 2.9 2 1 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AAAP01003809.1_16 - 7.2e-05 23.0 21.4 0.0048 17.3 2.2 3.8 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003809.1_16 - 0.019 15.5 19.1 0.39 11.3 6.1 3.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Pellino PF04710.14 AAAP01003809.1_16 - 0.037 12.7 0.3 0.044 12.5 0.3 1.1 1 0 0 1 1 1 0 Pellino Fer4_13 PF13370.6 AAAP01003809.1_16 - 0.074 13.6 17.5 0.3 11.7 4.0 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAAP01003809.1_16 - 0.16 12.7 0.5 0.16 12.7 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain ETF_QO PF05187.13 AAAP01003809.1_16 - 0.16 12.1 2.2 0.45 10.7 2.4 1.7 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 AAAP01003809.1_16 - 1.6 9.9 31.2 0.19 12.7 5.6 3.7 4 0 0 4 4 4 0 4Fe-4S binding domain Cupin_2 PF07883.11 AAAP01003809.1_17 - 3.6e-14 52.2 0.0 6.4e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AAAP01003809.1_17 - 0.046 13.4 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) FGE-sulfatase PF03781.16 AAAP01003809.1_18 - 5.3e-53 180.2 2.9 8.2e-53 179.6 2.9 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 NiFe-hyd_HybE PF11939.8 AAAP01003809.1_19 - 1.5e-39 135.3 0.0 1.8e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 [NiFe]-hydrogenase assembly, chaperone, HybE FBPase PF00316.20 AAAP01003809.1_20 - 3.1e-64 215.9 0.2 4e-64 215.6 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain MCPsignal PF00015.21 AAAP01003809.1_21 - 1.2e-32 113.1 25.4 1.2e-32 113.1 25.4 3.1 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003809.1_21 - 8.2e-09 35.7 0.4 8.2e-09 35.7 0.4 4.1 5 0 0 5 5 5 1 HAMP domain 4HB_MCP_1 PF12729.7 AAAP01003809.1_21 - 1e-05 25.2 0.8 1e-05 25.2 0.8 3.8 3 2 0 3 3 3 1 Four helix bundle sensory module for signal transduction DUF948 PF06103.11 AAAP01003809.1_21 - 0.00023 21.3 28.5 0.12 12.7 5.3 6.0 2 2 3 6 6 6 3 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003809.1_21 - 0.091 12.8 17.0 0.96 9.5 1.6 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) TcA_TcB_BD PF18276.1 AAAP01003809.1_21 - 0.22 10.6 4.6 0.069 12.2 0.7 2.1 2 0 0 2 2 2 0 Tc toxin complex TcA C-terminal TcB-binding domain kleA_kleC PF17383.2 AAAP01003809.1_21 - 0.32 11.3 5.0 9.5 6.6 0.0 4.2 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A AAA_13 PF13166.6 AAAP01003809.1_21 - 0.66 8.5 11.8 0.2 10.3 8.2 2.0 2 0 0 2 2 2 0 AAA domain Baculo_LEF5_C PF11792.8 AAAP01003809.1_21 - 0.76 9.5 4.6 20 4.9 0.1 3.5 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain SKA1 PF07160.12 AAAP01003809.1_21 - 1.5 8.6 5.3 1.8 8.3 2.2 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Laminin_II PF06009.12 AAAP01003809.1_21 - 2.7 8.0 16.1 1.9 8.5 0.6 3.9 1 1 3 4 4 4 0 Laminin Domain II CK1gamma_C PF12605.8 AAAP01003809.1_21 - 3 9.1 14.2 3.9 8.7 6.3 3.3 2 1 1 3 3 3 0 Casein kinase 1 gamma C terminal Laminin_I PF06008.14 AAAP01003809.1_21 - 5.9 6.5 21.9 0.33 10.6 2.2 3.3 2 1 0 3 3 3 0 Laminin Domain I SpoIIE PF07228.12 AAAP01003809.1_22 - 7e-30 104.4 0.0 1e-29 103.9 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAAP01003809.1_22 - 6.9e-24 84.2 0.0 1.1e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAAP01003809.1_23 - 0.0068 16.4 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain STAS PF01740.21 AAAP01003809.1_24 - 3.5e-12 46.0 0.0 3.6e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAAP01003809.1_24 - 1.2e-07 32.0 0.0 1.6e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 STAS domain GldM_N PF12081.8 AAAP01003809.1_25 - 0.0068 16.5 2.6 0.25 11.4 2.6 1.9 1 1 1 2 2 2 1 GldM N-terminal domain DUF948 PF06103.11 AAAP01003809.1_25 - 0.017 15.4 5.1 0.091 13.0 4.7 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 AAAP01003809.1_25 - 0.024 14.4 9.2 0.05 13.4 9.2 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Ferritin PF00210.24 AAAP01003809.1_25 - 0.034 14.1 1.1 0.28 11.1 0.8 1.9 1 1 1 2 2 2 0 Ferritin-like domain HrpB2 PF09487.10 AAAP01003809.1_25 - 0.034 14.6 2.7 0.045 14.2 2.5 1.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Laminin_II PF06009.12 AAAP01003809.1_25 - 0.037 14.0 5.2 0.071 13.1 4.6 1.7 1 1 1 2 2 2 0 Laminin Domain II ATP-synt_ab PF00006.25 AAAP01003809.1_25 - 0.037 13.7 0.5 0.043 13.5 0.5 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain GARP PF16731.5 AAAP01003809.1_25 - 0.056 13.1 9.1 0.06 13.0 9.1 1.0 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF1664 PF07889.12 AAAP01003809.1_25 - 0.059 13.4 2.8 0.51 10.4 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vps53_N PF04100.12 AAAP01003809.1_25 - 0.078 11.9 2.7 0.082 11.9 2.7 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal TMPIT PF07851.13 AAAP01003809.1_25 - 0.2 10.9 0.3 0.22 10.8 0.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein YtxH PF12732.7 AAAP01003809.1_25 - 0.98 10.0 4.5 18 6.0 4.5 2.5 1 1 0 1 1 1 0 YtxH-like protein LPP PF04728.13 AAAP01003809.1_25 - 8.2 6.9 11.0 3.7e+02 1.6 11.0 2.8 1 1 0 1 1 1 0 Lipoprotein leucine-zipper MttA_Hcf106 PF02416.16 AAAP01003810.1_1 - 3e-09 36.0 0.8 3.3e-09 35.9 0.8 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family SMC_ScpB PF04079.16 AAAP01003810.1_2 - 4.1e-32 111.0 0.0 5.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB SMC_ScpA PF02616.14 AAAP01003810.1_3 - 2.5e-12 47.2 0.0 5.5e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Segregation and condensation protein ScpA Rad21_Rec8 PF04824.16 AAAP01003810.1_3 - 0.0046 16.2 0.0 0.0097 15.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Peptidase_M50 PF02163.22 AAAP01003810.1_4 - 0.0012 18.2 4.1 0.0012 18.2 4.1 2.5 1 1 1 2 2 2 2 Peptidase family M50 Glyco_hydro_3 PF00933.21 AAAP01003810.1_5 - 8.6e-17 61.5 0.1 1e-16 61.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3 PF00933.21 AAAP01003810.1_6 - 1.6e-29 103.3 0.0 2e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain SPOR PF05036.13 AAAP01003810.1_7 - 3.1e-12 46.7 1.0 5.9e-12 45.8 1.0 1.5 1 0 0 1 1 1 1 Sporulation related domain DALR_1 PF05746.15 AAAP01003810.1_8 - 4.3e-28 97.9 0.0 7.4e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AAAP01003810.1_8 - 2.8e-22 79.1 0.1 8.2e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1d PF00750.19 AAAP01003810.1_8 - 3.2e-19 69.1 0.2 4.6e-18 65.3 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.18 AAAP01003810.1_8 - 1.4e-07 30.8 0.0 2.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AAAP01003810.1_8 - 6.5e-07 29.0 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AAAP01003810.1_8 - 2e-05 23.6 0.0 0.042 12.6 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AAAP01003810.1_8 - 0.0026 16.1 0.1 0.089 11.0 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1b PF00579.25 AAAP01003810.1_8 - 0.26 10.6 0.2 18 4.5 0.2 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) HD_assoc PF13286.6 AAAP01003810.1_9 - 7.9e-31 106.5 0.5 2.4e-30 104.9 0.1 2.1 2 0 0 2 2 2 1 Phosphohydrolase-associated domain HD PF01966.22 AAAP01003810.1_9 - 1.6e-14 54.2 0.2 4.4e-14 52.7 0.2 1.8 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAAP01003810.1_9 - 6.3e-05 22.5 0.0 0.00016 21.3 0.0 1.5 2 0 0 2 2 2 1 HDOD domain GGDEF PF00990.21 AAAP01003810.1_10 - 1.2e-36 125.9 0.0 1.6e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Fe-S_biosyn PF01521.20 AAAP01003810.1_11 - 5.5e-22 78.1 0.0 6.2e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Exo_endo_phos PF03372.23 AAAP01003810.1_13 - 2.1e-26 92.9 1.9 2.4e-26 92.7 1.9 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Haem_oxygenas_2 PF14518.6 AAAP01003810.1_14 - 7.3e-07 29.1 0.1 2.5e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Iron-containing redox enzyme SRR1 PF07985.12 AAAP01003810.1_14 - 0.03 14.4 0.1 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 SRR1 TENA_THI-4 PF03070.16 AAAP01003810.1_14 - 0.032 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF423 PF04241.15 AAAP01003810.1_14 - 0.063 13.5 0.1 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Response_reg PF00072.24 AAAP01003810.1_15 - 4.7e-19 68.6 0.0 1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Hemerythrin PF01814.23 AAAP01003810.1_15 - 7.5e-13 49.2 1.1 1.4e-12 48.4 1.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain BRCT_3 PF18428.1 AAAP01003810.1_15 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF573 PF04504.14 AAAP01003810.1_15 - 0.13 13.0 0.0 0.39 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 ILVD_EDD PF00920.21 AAAP01003810.1_16 - 1.1e-214 713.9 4.8 1.2e-214 713.7 4.8 1.0 1 0 0 1 1 1 1 Dehydratase family DivIC PF04977.15 AAAP01003810.1_17 - 0.001 18.8 1.9 0.011 15.5 3.4 1.8 2 0 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 AAAP01003810.1_17 - 0.0014 18.6 1.2 0.0024 17.9 1.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor ZapB PF06005.12 AAAP01003810.1_17 - 0.0017 18.8 1.8 0.0027 18.1 1.8 1.4 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 AAAP01003810.1_17 - 0.0025 18.0 2.6 0.0041 17.3 2.1 1.7 2 0 0 2 2 1 1 Homeobox associated leucine zipper CENP-Q PF13094.6 AAAP01003810.1_17 - 0.0085 16.3 1.2 0.0093 16.2 1.2 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.6 AAAP01003810.1_17 - 0.014 14.8 0.5 0.017 14.5 0.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1843 PF08898.10 AAAP01003810.1_17 - 0.018 15.6 2.3 0.018 15.6 2.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) K-box PF01486.17 AAAP01003810.1_17 - 0.018 15.2 0.6 0.027 14.6 0.6 1.3 1 0 0 1 1 1 0 K-box region DUF2353 PF09789.9 AAAP01003810.1_17 - 0.02 14.3 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Mto2_bdg PF12808.7 AAAP01003810.1_17 - 0.03 14.6 5.4 0.086 13.2 5.4 1.8 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NRBF2 PF08961.10 AAAP01003810.1_17 - 0.033 13.8 0.6 0.042 13.5 0.6 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4407 PF14362.6 AAAP01003810.1_17 - 0.033 13.6 0.2 0.037 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Halo_GVPC PF05465.13 AAAP01003810.1_17 - 0.034 14.4 5.9 1.4 9.2 0.6 3.1 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat Spc7 PF08317.11 AAAP01003810.1_17 - 0.049 12.5 0.7 0.067 12.1 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 AAAP01003810.1_17 - 0.053 13.6 7.7 0.062 13.4 5.0 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 HAUS-augmin3 PF14932.6 AAAP01003810.1_17 - 0.058 13.0 0.2 0.074 12.6 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 JIP_LZII PF16471.5 AAAP01003810.1_17 - 0.059 13.6 1.9 0.19 11.9 2.2 1.6 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II HIP1_clath_bdg PF16515.5 AAAP01003810.1_17 - 0.062 13.9 1.0 0.094 13.3 1.0 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 AAAP01003810.1_17 - 0.062 13.4 2.4 0.2 11.8 2.6 1.6 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF2381 PF09544.10 AAAP01003810.1_17 - 0.073 12.6 0.9 0.086 12.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Rootletin PF15035.6 AAAP01003810.1_17 - 0.074 13.1 0.8 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.15 AAAP01003810.1_17 - 0.098 12.8 4.3 0.21 11.7 4.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper MAD PF05557.13 AAAP01003810.1_17 - 0.11 10.9 1.1 0.13 10.6 1.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.11 AAAP01003810.1_17 - 0.11 12.9 0.5 0.17 12.3 0.5 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 AAAP01003810.1_17 - 0.12 11.8 0.4 0.14 11.6 0.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1640 PF07798.11 AAAP01003810.1_17 - 0.14 12.2 0.7 0.2 11.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2968 PF11180.8 AAAP01003810.1_17 - 0.2 11.3 0.9 0.31 10.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Metal_resist PF13801.6 AAAP01003810.1_17 - 0.2 11.8 5.9 0.26 11.5 4.4 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Jnk-SapK_ap_N PF09744.9 AAAP01003810.1_17 - 0.26 11.5 5.3 0.4 10.9 5.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NUDE_C PF04880.13 AAAP01003810.1_17 - 0.32 11.5 3.1 0.45 11.0 3.1 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Spc24 PF08286.11 AAAP01003810.1_17 - 0.48 10.7 2.2 0.68 10.2 2.3 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 AAAP01003810.1_17 - 0.72 10.4 8.8 1.3 9.5 8.5 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 AAAP01003810.1_17 - 1.2 9.6 4.2 2 8.9 3.6 1.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HAD_2 PF13419.6 AAAP01003810.1_18 - 1e-15 58.3 0.0 1.6e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003810.1_18 - 2.6e-10 41.0 0.0 3.5e-08 34.0 0.0 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003810.1_18 - 0.00022 21.2 0.0 0.00055 20.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 AAAP01003810.1_18 - 0.0067 16.9 0.1 0.0092 16.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01003810.1_18 - 0.016 15.3 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Erythro-docking PF09277.11 AAAP01003810.1_18 - 2.4 8.1 5.2 1.4 8.8 1.0 2.2 2 0 0 2 2 2 0 Erythronolide synthase, docking SLT PF01464.20 AAAP01003810.1_19 - 3.6e-25 87.9 0.0 7.7e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain TPR_2 PF07719.17 AAAP01003810.1_19 - 1.1 9.6 5.8 13 6.2 0.2 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DHDPS PF00701.22 AAAP01003810.1_20 - 1.3e-93 312.9 0.0 1.4e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 AAAP01003810.1_20 - 0.034 14.2 0.2 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 PA domain SmpB PF01668.18 AAAP01003810.1_21 - 6.8e-55 184.9 0.1 7.7e-55 184.7 0.1 1.0 1 0 0 1 1 1 1 SmpB protein Oxidored_molyb PF00174.19 AAAP01003810.1_22 - 2.5e-35 121.6 0.0 3.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain DHDPS PF00701.22 AAAP01003810.1_23 - 8.7e-37 126.4 0.0 9.7e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Engrail_1_C_sig PF10525.9 AAAP01003810.1_23 - 0.41 9.9 1.8 0.8 9.0 1.8 1.4 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain DUF4147 PF13660.6 AAAP01003810.1_24 - 1.7e-81 273.1 1.1 2.8e-81 272.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AAAP01003810.1_24 - 2.3e-37 127.5 1.3 6.8e-37 126.0 0.8 2.0 2 0 0 2 2 2 1 MOFRL family Mem_trans PF03547.18 AAAP01003810.1_25 - 2.8e-07 29.3 0.4 3.5e-07 29.0 0.4 1.0 1 0 0 1 1 1 1 Membrane transport protein TMEM215 PF15746.5 AAAP01003810.1_25 - 0.0077 15.7 2.0 0.011 15.2 2.0 1.2 1 0 0 1 1 1 1 TMEM215 family GDC-P PF02347.16 AAAP01003811.1_1 - 6.8e-115 384.3 0.0 8.3e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 AAAP01003811.1_1 - 1.7e-06 27.3 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01003811.1_1 - 0.0016 17.1 0.3 0.0063 15.1 0.1 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme SLH PF00395.20 AAAP01003811.1_1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 S-layer homology domain GCV_H PF01597.19 AAAP01003811.1_2 - 1.2e-38 131.8 0.1 1.3e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 AAAP01003811.1_2 - 0.072 12.9 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme GCV_T PF01571.21 AAAP01003811.1_3 - 6.4e-87 291.2 0.1 7.7e-87 290.9 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AAAP01003811.1_3 - 7.2e-15 54.7 0.1 1.6e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain LYTB PF02401.18 AAAP01003811.1_5 - 4.3e-86 288.4 0.1 4.9e-86 288.2 0.1 1.0 1 0 0 1 1 1 1 LytB protein Ferrochelatase PF00762.19 AAAP01003811.1_5 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 2 0 0 2 2 2 0 Ferrochelatase APH PF01636.23 AAAP01003811.1_7 - 3.1e-21 76.4 0.3 4e-21 76.0 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AAAP01003811.1_7 - 2.1e-05 24.2 0.1 2.8e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RNase_H PF00075.24 AAAP01003811.1_8 - 4.9e-51 172.7 0.0 5.7e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 AAAP01003811.1_8 - 0.13 12.0 0.2 1 9.2 0.0 2.2 2 1 0 2 2 2 0 Reverse transcriptase-like Glycoprot_B_PH2 PF17417.2 AAAP01003811.1_9 - 0.12 12.8 0.0 3.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain Response_reg PF00072.24 AAAP01003811.1_10 - 1.9e-24 86.0 0.8 2.9e-24 85.4 0.8 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Hydrolase PF00702.26 AAAP01003811.1_10 - 0.0038 17.5 0.0 0.0076 16.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GGDEF PF00990.21 AAAP01003811.1_11 - 3.4e-49 166.7 0.4 1.4e-48 164.7 0.5 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Phage_GP20 PF06810.11 AAAP01003811.1_11 - 0.0004 20.2 1.1 0.00099 18.9 1.1 1.6 1 0 0 1 1 1 1 Phage minor structural protein GP20 Prefoldin_2 PF01920.20 AAAP01003811.1_11 - 0.058 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit Pentapeptide PF00805.22 AAAP01003811.1_12 - 1.2e-37 127.0 23.5 2.3e-11 43.1 1.5 3.7 1 1 5 6 6 6 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AAAP01003811.1_12 - 2.5e-13 50.0 0.0 2.6e-08 33.9 0.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AAAP01003811.1_12 - 1.7e-09 37.6 0.8 8.3e-05 22.7 1.1 3.4 1 1 0 2 2 2 1 Pentapeptide repeats (9 copies) TPR_12 PF13424.6 AAAP01003811.1_13 - 8.9e-17 61.2 27.5 1.1e-09 38.4 4.1 3.5 3 1 0 3 3 3 3 Tetratricopeptide repeat SNAP PF14938.6 AAAP01003811.1_13 - 7.8e-11 41.9 5.1 7.2e-06 25.6 0.1 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 AAAP01003811.1_13 - 2.3e-09 36.6 25.9 0.31 11.3 0.1 6.8 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003811.1_13 - 0.00011 21.9 12.7 2.9 7.9 0.1 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003811.1_13 - 0.00011 21.7 18.6 0.03 13.7 8.6 1.9 1 1 0 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 AAAP01003811.1_13 - 0.00024 21.1 9.7 13 6.3 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2225 PF09986.9 AAAP01003811.1_13 - 0.0027 17.5 0.0 0.27 10.9 0.0 2.5 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 AAAP01003811.1_13 - 0.011 15.6 34.8 0.23 11.4 1.8 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003811.1_13 - 0.018 15.8 31.1 4.6 8.3 2.7 6.2 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003811.1_13 - 0.025 15.1 24.2 1.5 9.4 1.9 5.3 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003811.1_13 - 0.036 13.8 3.9 0.36 10.6 0.1 3.5 3 0 0 3 3 3 0 TPR repeat RPN7 PF10602.9 AAAP01003811.1_13 - 0.041 13.6 0.7 0.074 12.8 0.2 1.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 MIT PF04212.18 AAAP01003811.1_13 - 0.078 13.1 8.9 3.2 7.9 0.3 3.9 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 AAAP01003811.1_13 - 0.11 12.6 22.9 1.1 9.5 0.3 6.9 6 2 1 7 7 7 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 AAAP01003811.1_13 - 0.13 12.5 0.3 0.13 12.5 0.3 2.5 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 TPR_6 PF13174.6 AAAP01003811.1_13 - 2.7 8.8 14.5 9.2 7.1 0.1 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TC1 PF15063.6 AAAP01003811.1_13 - 4.1 7.3 6.5 47 3.9 0.0 3.7 3 1 1 4 4 4 0 Thyroid cancer protein 1 NUDIX PF00293.28 AAAP01003811.1_14 - 2.3e-09 37.4 0.1 3e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.6 AAAP01003811.1_14 - 5.7e-08 32.5 0.0 9.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Nudix N-terminal ADH_zinc_N PF00107.26 AAAP01003811.1_17 - 6e-28 97.4 0.6 1.2e-27 96.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01003811.1_17 - 3.5e-20 73.4 0.0 6.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003811.1_17 - 2.7e-11 43.3 0.2 8.4e-11 41.7 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NeuB PF03102.14 AAAP01003811.1_18 - 2e-88 295.9 0.0 2.3e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 AAAP01003811.1_18 - 1.1e-09 38.8 0.0 2.9e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 SAF domain Glyco_tran_28_C PF04101.16 AAAP01003811.1_19 - 0.0012 18.8 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF354 PF04007.12 AAAP01003811.1_19 - 0.093 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF354) Acetyltransf_3 PF13302.7 AAAP01003811.1_20 - 1.8e-16 61.1 0.0 2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003811.1_20 - 6.5e-08 32.8 0.0 8.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AAAP01003811.1_20 - 6.4e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AAAP01003811.1_20 - 0.00051 19.8 0.1 0.0058 16.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AAAP01003811.1_20 - 0.0026 17.9 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003811.1_20 - 0.0029 17.5 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01003811.1_20 - 0.0038 17.6 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AAAP01003811.1_20 - 0.048 13.2 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase PBECR2 PF18810.1 AAAP01003811.1_20 - 0.18 12.1 0.0 0.51 10.6 0.0 1.8 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 DegT_DnrJ_EryC1 PF01041.17 AAAP01003811.1_21 - 2.4e-107 359.4 0.0 3.8e-107 358.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Polysacc_synt_2 PF02719.15 AAAP01003811.1_21 - 2e-99 332.4 0.0 2.6e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAAP01003811.1_21 - 6.3e-22 78.2 0.0 3.3e-21 75.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003811.1_21 - 8.2e-14 51.7 0.0 2.4e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003811.1_21 - 4e-13 49.0 0.0 7.3e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Aminotran_1_2 PF00155.21 AAAP01003811.1_21 - 1.3e-12 47.6 0.0 1.3e-11 44.4 0.0 2.4 3 0 0 3 3 3 1 Aminotransferase class I and II RmlD_sub_bind PF04321.17 AAAP01003811.1_21 - 3.4e-10 39.5 0.0 7.3e-09 35.1 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAAP01003811.1_21 - 1.4e-08 34.9 0.0 4.8e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)H-binding Beta_elim_lyase PF01212.21 AAAP01003811.1_21 - 1.4e-08 34.4 0.4 2.3e-08 33.7 0.4 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase adh_short PF00106.25 AAAP01003811.1_21 - 3.8e-07 29.7 0.1 6.7e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AAAP01003811.1_21 - 1.1e-05 24.8 1.2 0.0006 19.0 0.6 2.9 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.13 AAAP01003811.1_21 - 1.5e-05 24.6 0.1 3.1e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Cys_Met_Meta_PP PF01053.20 AAAP01003811.1_21 - 0.00025 19.7 0.0 0.00042 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme KR PF08659.10 AAAP01003811.1_21 - 0.00052 20.0 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 KR domain HutP PF09021.11 AAAP01003811.1_21 - 0.091 13.1 0.2 0.091 13.1 0.2 1.7 2 0 0 2 2 1 0 HutP CTP_transf_3 PF02348.19 AAAP01003811.1_22 - 2.7e-18 66.7 0.0 3.5e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01003811.1_22 - 7.9e-09 36.1 1.1 1.4e-08 35.2 0.4 1.6 1 1 0 2 2 2 1 MobA-like NTP transferase domain LAL_C2 PF18603.1 AAAP01003811.1_22 - 0.022 14.9 0.7 0.045 13.9 0.7 1.5 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 DUF2064 PF09837.9 AAAP01003811.1_22 - 0.041 13.7 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF3304 PF11745.8 AAAP01003811.1_22 - 0.12 12.8 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) PTA_PTB PF01515.19 AAAP01003811.1_23 - 8.2e-78 261.9 0.0 9.2e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase GAF PF01590.26 AAAP01003811.1_23 - 0.026 15.2 0.0 0.22 12.2 0.0 2.1 1 1 1 2 2 2 0 GAF domain 2-oxoacid_dh PF00198.23 AAAP01003812.1_1 - 7.2e-33 114.0 0.0 7.8e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 2-oxoacid_dh PF00198.23 AAAP01003812.1_2 - 1.6e-37 129.2 0.0 2.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AAAP01003812.1_2 - 7.6e-23 80.1 1.2 1.1e-22 79.7 0.6 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 AAAP01003812.1_2 - 3.3e-13 49.7 0.8 7.7e-13 48.5 0.8 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AAAP01003812.1_2 - 0.018 14.9 1.0 18 5.3 0.0 3.3 2 1 1 3 3 3 0 Biotin-lipoyl like GCV_H PF01597.19 AAAP01003812.1_2 - 0.045 13.6 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein ACC_epsilon PF13822.6 AAAP01003812.1_2 - 2.1 9.1 25.2 1.3 9.7 2.1 2.9 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DUF3682 PF12446.8 AAAP01003812.1_2 - 4.9 7.6 16.4 9.8 6.7 16.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Transket_pyr PF02779.24 AAAP01003812.1_3 - 5.2e-64 215.2 0.0 1.1e-63 214.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 AAAP01003812.1_3 - 6.6e-59 199.3 0.0 1.5e-58 198.1 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 AAAP01003812.1_3 - 2.1e-52 176.9 0.0 3.3e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 AAAP01003812.1_3 - 2.2e-17 62.4 0.3 5.1e-17 61.2 0.3 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF501 PF04417.12 AAAP01003812.1_3 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) CoA_binding PF02629.19 AAAP01003812.1_4 - 1.3e-31 109.1 0.6 1.3e-31 109.1 0.6 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AAAP01003812.1_4 - 7.2e-19 68.1 0.4 1.1e-18 67.6 0.4 1.2 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AAAP01003812.1_4 - 1.4e-09 37.9 0.1 2.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAAP01003812.1_4 - 0.00096 19.6 0.1 0.0024 18.4 0.1 1.7 2 0 0 2 2 2 1 CoA binding domain Phage_GPO PF05929.11 AAAP01003812.1_4 - 0.13 11.8 0.1 0.18 11.4 0.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ATP-grasp_2 PF08442.10 AAAP01003812.1_5 - 4.4e-78 261.5 2.8 4.7e-78 261.4 1.2 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 AAAP01003812.1_5 - 2.3e-28 99.0 0.7 3.9e-28 98.2 0.7 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AAAP01003812.1_5 - 5.2e-12 45.7 1.0 5.2e-12 45.7 1.0 2.2 2 1 0 2 2 2 1 ATP-grasp domain Ldh_1_N PF00056.23 AAAP01003812.1_6 - 7.2e-38 129.9 0.3 1.2e-37 129.1 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AAAP01003812.1_6 - 1.3e-29 103.3 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 AAAP01003812.1_6 - 0.0036 16.9 0.3 0.04 13.5 0.1 2.2 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 AAAP01003812.1_6 - 0.0071 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain UDPG_MGDP_dh_N PF03721.14 AAAP01003812.1_6 - 0.02 14.5 0.5 0.1 12.1 0.5 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CLN3 PF02487.17 AAAP01003812.1_8 - 0.0057 15.8 1.9 0.023 13.7 0.7 2.3 2 1 1 3 3 3 1 CLN3 protein kleA_kleC PF17383.2 AAAP01003812.1_8 - 7.1 7.0 7.2 0.96 9.8 1.3 2.4 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A OmpA PF00691.20 AAAP01003812.1_9 - 8.6e-22 77.3 0.0 1.9e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 OmpA family AFG1_ATPase PF03969.16 AAAP01003812.1_10 - 8.7e-122 406.5 0.0 1.2e-121 406.1 0.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase IstB_IS21 PF01695.17 AAAP01003812.1_10 - 0.0012 18.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AAAP01003812.1_10 - 0.0046 16.8 0.0 0.4 10.5 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_29 PF13555.6 AAAP01003812.1_10 - 0.0094 15.7 0.4 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003812.1_10 - 0.025 14.9 0.9 2 8.8 0.2 3.1 2 2 1 3 3 3 0 AAA ATPase domain AAA_10 PF12846.7 AAAP01003812.1_10 - 0.028 13.3 0.0 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 AAAP01003812.1_10 - 0.053 13.8 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003812.1_10 - 0.073 13.6 0.0 2.6 8.6 0.0 2.3 1 1 1 2 2 2 0 ABC transporter AAA_5 PF07728.14 AAAP01003812.1_10 - 0.19 11.7 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Fer2_3 PF13085.6 AAAP01003812.1_13 - 2.2e-32 111.3 0.0 3.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 AAAP01003812.1_13 - 4.8e-11 42.9 18.9 1.3e-08 35.2 7.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003812.1_13 - 3.1e-09 37.2 3.4 3.1e-09 37.2 3.4 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003812.1_13 - 1.4e-06 28.3 5.5 1.4e-06 28.3 5.5 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 AAAP01003812.1_13 - 0.0044 16.9 0.2 0.0044 16.9 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 AAAP01003812.1_13 - 0.027 14.6 7.5 0.027 14.6 7.5 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003812.1_13 - 0.83 10.3 16.0 2.2 8.9 11.2 3.2 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003812.1_13 - 1 10.4 9.8 3.2 8.7 1.2 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain FAD_binding_2 PF00890.24 AAAP01003812.1_14 - 6.9e-124 414.1 4.9 8.7e-124 413.8 4.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAAP01003812.1_14 - 2.7e-42 143.8 0.8 4e-42 143.2 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AAAP01003812.1_14 - 1.8e-05 24.1 0.3 0.00012 21.4 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003812.1_14 - 0.001 18.2 1.2 0.068 12.2 2.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 AAAP01003812.1_14 - 0.0083 15.4 1.0 0.026 13.8 0.3 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 AAAP01003812.1_14 - 0.035 13.4 2.6 0.032 13.5 0.9 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 AAAP01003812.1_14 - 0.085 11.5 0.8 0.58 8.8 1.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Sdh_cyt PF01127.22 AAAP01003812.1_15 - 3.2e-19 69.1 3.4 3.7e-19 68.9 3.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.12 AAAP01003812.1_15 - 3.5e-05 23.5 4.2 0.00045 19.9 4.2 2.0 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Osw5 PF17062.5 AAAP01003812.1_15 - 0.01 15.9 2.5 0.036 14.2 0.1 2.2 2 0 0 2 2 2 0 Outer spore wall 5 Fumarate_red_C PF02300.17 AAAP01003812.1_15 - 0.17 12.0 4.5 0.24 11.5 4.5 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit C Sdh_cyt PF01127.22 AAAP01003812.1_16 - 3.1e-31 107.9 4.4 3.8e-31 107.6 4.4 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AAAP01003812.1_16 - 6.4e-05 23.0 1.6 0.00045 20.3 0.9 1.9 1 1 1 2 2 2 2 Fumarate reductase subunit D NMD3 PF04981.13 AAAP01003813.1_1 - 0.021 14.3 0.2 0.047 13.2 0.0 1.6 1 1 0 1 1 1 0 NMD3 family zf-RING_7 PF02591.15 AAAP01003813.1_1 - 0.42 10.9 4.6 0.54 10.5 0.1 3.3 4 0 0 4 4 4 0 C4-type zinc ribbon domain FolB PF02152.18 AAAP01003813.1_2 - 8e-26 90.8 1.1 9.2e-26 90.6 1.1 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase DUF2312 PF10073.9 AAAP01003813.1_3 - 2.1e-33 113.8 5.4 2.5e-33 113.5 5.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) Val_tRNA-synt_C PF10458.9 AAAP01003813.1_3 - 0.0033 17.7 0.5 0.0043 17.3 0.5 1.2 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm CPSase_L_D3 PF02787.19 AAAP01003813.1_3 - 0.046 14.1 0.3 0.053 13.9 0.3 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF4303 PF14136.6 AAAP01003813.1_3 - 0.079 12.7 0.4 0.089 12.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) PhaP_Bmeg PF09602.10 AAAP01003813.1_3 - 0.096 12.6 2.0 0.48 10.3 0.1 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FGase PF05013.12 AAAP01003813.1_5 - 9.9e-40 137.0 0.0 1.1e-39 136.8 0.0 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase Ribosomal_L36 PF00444.18 AAAP01003813.1_6 - 7.4e-19 67.7 4.2 8.2e-19 67.5 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 HATPase_c PF02518.26 AAAP01003813.1_7 - 4.3e-31 107.7 0.0 1e-30 106.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003813.1_7 - 3.8e-27 94.7 0.0 1.8e-23 82.8 0.0 3.5 3 1 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 AAAP01003813.1_7 - 4.8e-20 71.4 8.8 1e-18 67.1 0.3 4.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003813.1_7 - 3.3e-09 37.0 1.0 1.9e-08 34.5 0.1 3.0 2 0 0 2 2 2 1 HAMP domain Hpt PF01627.23 AAAP01003813.1_7 - 1.6e-05 25.1 3.2 1.6e-05 25.1 3.2 2.9 2 0 0 2 2 2 1 Hpt domain PAS_8 PF13188.7 AAAP01003813.1_7 - 0.00024 21.0 0.0 0.00089 19.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAAP01003813.1_7 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003813.1_7 - 0.0022 18.2 0.0 0.0074 16.5 0.0 2.0 1 0 0 1 1 1 1 PAS fold 7TMR-HDED PF07697.11 AAAP01003813.1_7 - 6 6.9 6.5 19 5.3 0.1 2.4 2 0 0 2 2 2 0 7TM-HD extracellular Radical_SAM PF04055.21 AAAP01003813.1_8 - 2e-14 54.3 0.0 3.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TPR_19 PF14559.6 AAAP01003813.1_8 - 3.3e-10 40.3 9.1 1.1e-07 32.3 0.4 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat SPASM PF13186.6 AAAP01003813.1_8 - 4.7e-08 33.4 0.5 9.4e-08 32.5 0.5 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain TPR_12 PF13424.6 AAAP01003813.1_8 - 1e-06 28.9 8.1 7.2e-05 23.0 2.4 3.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003813.1_8 - 4.5e-06 27.2 22.8 0.00031 21.3 8.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003813.1_8 - 3e-05 23.6 2.6 0.0021 17.7 0.2 3.3 3 0 0 3 3 3 1 TPR repeat Fer4_14 PF13394.6 AAAP01003813.1_8 - 8.4e-05 22.7 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain ANAPC3 PF12895.7 AAAP01003813.1_8 - 0.00061 20.0 0.1 0.016 15.4 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AAAP01003813.1_8 - 0.0035 18.0 23.2 0.059 14.2 0.8 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003813.1_8 - 0.0039 17.7 22.8 0.15 12.8 0.9 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat Fer4_12 PF13353.6 AAAP01003813.1_8 - 0.0039 17.5 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain TPR_2 PF07719.17 AAAP01003813.1_8 - 0.014 15.5 12.0 0.4 10.9 0.2 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003813.1_8 - 0.73 9.8 14.0 0.35 10.8 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003813.1_8 - 0.87 9.5 4.2 9.9 6.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 AAAP01003813.1_9 - 1e-80 271.4 0.0 1.3e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003813.1_9 - 1.2e-22 80.6 0.4 2.7e-22 79.5 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RecO_C PF02565.15 AAAP01003813.1_11 - 9.6e-28 97.0 1.0 3.1e-27 95.3 0.7 1.8 2 0 0 2 2 2 1 Recombination protein O C terminal RecO_N PF11967.8 AAAP01003813.1_11 - 1e-14 54.2 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Recombination protein O N terminal MMR_HSR1 PF01926.23 AAAP01003813.1_12 - 3.1e-25 88.5 0.1 6e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 AAAP01003813.1_12 - 1.7e-19 69.4 0.4 3.3e-19 68.5 0.4 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 AAAP01003813.1_12 - 7.6e-15 54.8 0.1 1.2e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAAP01003813.1_12 - 1.7e-11 44.5 2.6 3e-06 27.4 0.6 2.5 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 AAAP01003813.1_12 - 5.2e-11 42.5 0.4 4.9e-08 32.8 0.4 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 AAAP01003813.1_12 - 4.5e-10 39.4 0.0 1.7e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 AAAP01003813.1_12 - 3.4e-09 36.8 0.2 0.002 18.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 AAAP01003813.1_12 - 4.1e-07 29.6 0.1 6.1e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 AAAP01003813.1_12 - 1.4e-05 24.8 0.6 0.0012 18.5 0.1 2.4 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 AAAP01003813.1_12 - 0.00018 21.1 0.2 0.37 10.2 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_28 PF13521.6 AAAP01003813.1_12 - 0.0022 18.2 0.9 0.079 13.2 0.1 2.8 2 1 1 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 AAAP01003813.1_12 - 0.0024 17.7 0.1 0.51 10.1 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 AAAP01003813.1_12 - 0.0041 17.1 0.0 0.0097 15.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FtsK_SpoIIIE PF01580.18 AAAP01003813.1_12 - 0.0048 16.3 0.0 0.038 13.3 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family SRP54 PF00448.22 AAAP01003813.1_12 - 0.0058 16.3 0.3 0.41 10.3 0.1 2.3 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Ras PF00071.22 AAAP01003813.1_12 - 0.013 15.1 0.0 0.047 13.3 0.0 1.8 1 1 0 1 1 1 0 Ras family MeaB PF03308.16 AAAP01003813.1_12 - 0.017 14.2 0.2 0.31 10.0 0.2 2.3 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AAAP01003813.1_12 - 0.026 14.9 0.9 2.1 8.7 0.0 2.8 2 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01003813.1_12 - 0.026 14.8 0.1 0.1 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain GBP PF02263.19 AAAP01003813.1_12 - 0.051 12.8 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.27 AAAP01003813.1_12 - 0.064 13.8 0.3 0.19 12.2 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 AAAP01003813.1_12 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 AAAP01003813.1_12 - 0.13 12.5 0.2 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ribonucleas_3_3 PF14622.6 AAAP01003813.1_14 - 8.7e-33 113.2 0.0 1.2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AAAP01003813.1_14 - 4.3e-17 62.7 0.0 7.5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 AAAP01003813.1_14 - 2.3e-13 50.6 0.0 3.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 AAAP01003813.1_14 - 0.086 13.1 0.1 0.43 10.9 0.0 2.2 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Peptidase_S24 PF00717.23 AAAP01003813.1_15 - 1.1e-18 67.0 0.3 1.8e-18 66.2 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AAAP01003813.1_15 - 1.8e-10 40.7 0.2 0.00076 19.3 0.1 2.5 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 PilN PF05137.13 AAAP01003813.1_15 - 0.098 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) ACPS PF01648.20 AAAP01003813.1_16 - 1.1e-18 67.4 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily tRNA_synthFbeta PF17759.1 AAAP01003813.1_16 - 0.071 12.5 0.0 0.086 12.3 0.0 1.0 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain AbfS_sensor PF18225.1 AAAP01003813.1_16 - 0.093 12.7 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain Fumerase_C PF05683.12 AAAP01003813.1_16 - 0.13 11.5 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Fumarase C-terminus PdxJ PF03740.13 AAAP01003813.1_17 - 3.6e-99 330.6 0.8 4.1e-99 330.5 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 AAAP01003813.1_17 - 5.5e-05 22.7 1.9 0.00017 21.1 1.9 2.0 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Agenet PF05641.12 AAAP01003813.1_18 - 0.00068 20.0 0.0 0.00093 19.6 0.0 1.2 1 0 0 1 1 1 1 Agenet domain SAWADEE PF16719.5 AAAP01003813.1_18 - 0.2 11.7 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 SAWADEE domain PepSY_2 PF13670.6 AAAP01003813.1_18 - 0.53 10.3 2.1 4.8 7.3 0.5 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain HD_4 PF13328.6 AAAP01003813.1_19 - 4.7e-46 156.4 0.1 8.3e-46 155.6 0.1 1.4 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AAAP01003813.1_19 - 1.7e-38 131.5 0.1 5.4e-38 129.9 0.0 1.9 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TGS PF02824.21 AAAP01003813.1_19 - 2e-20 72.6 0.0 9.1e-20 70.5 0.0 2.0 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.6 AAAP01003813.1_19 - 2.7e-19 69.6 0.7 1e-18 67.7 0.6 2.1 2 0 0 2 2 2 1 ACT domain HD PF01966.22 AAAP01003813.1_19 - 4.2e-08 33.5 0.3 8e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 HD domain ACT PF01842.25 AAAP01003813.1_19 - 0.00065 19.4 0.7 0.0028 17.4 0.3 2.3 2 0 0 2 2 2 1 ACT domain ThiS PF02597.20 AAAP01003813.1_19 - 0.015 15.9 0.0 0.048 14.3 0.0 1.8 1 0 0 1 1 1 0 ThiS family RNA_pol_Rpb6 PF01192.22 AAAP01003813.1_20 - 2.7e-14 52.8 0.0 4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF3911 PF13050.6 AAAP01003813.1_20 - 0.076 13.1 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) NYN PF01936.18 AAAP01003813.1_21 - 1.4e-38 132.6 0.0 1.8e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 NYN domain UDG PF03167.19 AAAP01003813.1_22 - 1.1e-19 70.9 0.0 1.4e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily NadA PF02445.16 AAAP01003814.1_1 - 3.4e-64 216.9 0.0 3.8e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein Response_reg PF00072.24 AAAP01003814.1_2 - 3.5e-11 43.3 0.0 4.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Hpr_kinase_N PF02603.16 AAAP01003814.1_2 - 0.015 15.3 0.0 0.048 13.7 0.0 1.8 2 0 0 2 2 2 0 HPr Serine kinase N terminus DRTGG PF07085.12 AAAP01003814.1_2 - 0.06 13.1 0.0 0.28 11.0 0.0 1.9 1 1 0 1 1 1 0 DRTGG domain E1-E2_ATPase PF00122.20 AAAP01003814.1_3 - 6.2e-54 182.3 1.6 1.4e-53 181.1 1.6 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AAAP01003814.1_3 - 1.2e-45 155.4 1.0 1.2e-45 155.4 1.0 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AAAP01003814.1_3 - 2.6e-22 80.2 6.8 1.3e-21 77.9 6.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AAAP01003814.1_3 - 1.1e-15 57.0 0.0 2.1e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AAAP01003814.1_3 - 5.9e-14 51.9 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 AAAP01003814.1_3 - 4e-05 24.1 0.5 0.00013 22.4 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003814.1_3 - 0.0009 19.1 0.5 0.021 14.6 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Response_reg PF00072.24 AAAP01003814.1_4 - 2.8e-20 72.6 0.0 4.1e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003814.1_4 - 2.8e-18 65.2 0.4 4.6e-18 64.5 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003814.1_4 - 6.2e-11 41.8 0.4 1.3e-10 40.8 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003814.1_4 - 5.7e-06 25.7 0.2 1.3e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AAAP01003814.1_4 - 0.00057 20.3 0.1 0.0046 17.4 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAAP01003814.1_4 - 0.0023 17.7 0.2 2.8 7.8 0.0 2.8 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 AAAP01003814.1_4 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AAAP01003814.1_4 - 0.022 14.8 0.3 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003814.1_4 - 0.078 12.6 0.1 0.5 10.0 0.0 2.1 1 1 1 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AAAP01003814.1_4 - 0.11 12.3 0.0 0.76 9.7 0.0 2.3 1 1 1 2 2 2 0 Homeodomain-like domain DUF952 PF06108.12 AAAP01003814.1_5 - 2.8e-27 94.5 0.0 3.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DHO_dh PF01180.21 AAAP01003814.1_6 - 2.8e-97 325.5 0.0 3.2e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 AAAP01003814.1_6 - 0.007 15.8 0.7 0.011 15.1 0.7 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase DUF1454 PF07305.12 AAAP01003814.1_6 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1454) Hydrolase_6 PF13344.6 AAAP01003814.1_7 - 4.7e-15 55.5 0.0 8.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003814.1_7 - 5.7e-14 51.9 0.4 1.1e-13 51.0 0.4 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AAAP01003814.1_7 - 3.7e-09 37.2 0.4 0.0018 18.6 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AAAP01003814.1_7 - 3.5e-08 33.7 0.0 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase YAcAr PF10686.9 AAAP01003814.1_7 - 0.0015 18.5 1.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 YspA, cpYpsA-related SLOG family Pyr_redox_2 PF07992.14 AAAP01003814.1_8 - 1.2e-23 83.8 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003814.1_8 - 3.4e-19 69.2 0.0 3.5e-16 59.3 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003814.1_8 - 2.1e-10 41.0 3.4 1.6e-09 38.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003814.1_8 - 2.1e-07 30.0 0.1 0.0059 15.3 0.4 3.1 3 0 0 3 3 3 2 HI0933-like protein FMO-like PF00743.19 AAAP01003814.1_8 - 8.8e-05 21.1 0.4 0.00013 20.5 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 AAAP01003814.1_8 - 0.00013 21.3 0.3 0.0063 15.8 0.2 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 AAAP01003814.1_8 - 0.00051 20.5 1.4 0.013 16.0 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 AAAP01003814.1_8 - 0.0037 16.7 0.2 0.11 11.8 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AAAP01003814.1_8 - 0.0052 16.0 0.1 0.034 13.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AAAP01003814.1_8 - 0.016 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 AAAP01003814.1_8 - 0.021 15.3 0.1 4.2 7.9 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 AAAP01003814.1_8 - 0.024 14.6 0.1 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AAAP01003814.1_8 - 0.041 13.1 1.7 0.11 11.7 0.2 2.2 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 AAAP01003814.1_8 - 0.06 12.4 6.0 0.14 11.2 1.2 2.7 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 AAAP01003814.1_8 - 0.081 12.5 2.3 3.8 7.0 0.6 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase GARS_N PF02844.15 AAAP01003814.1_8 - 0.1 13.4 0.0 0.46 11.3 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Oxidored_nitro PF00148.19 AAAP01003814.1_8 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF43 PF01861.16 AAAP01003814.1_8 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain AlaDh_PNT_C PF01262.21 AAAP01003814.1_8 - 0.13 11.5 0.1 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Mqo PF06039.15 AAAP01003814.1_8 - 0.23 10.0 0.0 0.52 8.8 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF2336 PF10098.9 AAAP01003814.1_9 - 1.6e-62 211.3 35.8 1.4e-61 208.3 15.4 2.2 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2336) LRV PF01816.17 AAAP01003814.1_9 - 0.013 15.9 0.9 0.013 15.9 0.9 6.5 7 0 0 7 7 7 0 Leucine rich repeat variant Dicer_dimer PF03368.14 AAAP01003814.1_9 - 0.1 12.8 2.1 0.18 12.0 0.2 2.3 2 0 0 2 2 2 0 Dicer dimerisation domain TAF PF02969.17 AAAP01003814.1_9 - 0.51 10.5 3.4 29 4.9 0.0 3.6 3 1 1 4 4 4 0 TATA box binding protein associated factor (TAF) PAS PF00989.25 AAAP01003814.1_10 - 3.8e-08 33.3 0.0 0.0033 17.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003814.1_10 - 1e-07 32.1 0.0 8.7e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAAP01003814.1_10 - 4.6e-07 30.1 0.7 0.012 15.9 0.1 3.8 2 2 1 3 3 3 2 PAS fold GAF_3 PF13492.6 AAAP01003814.1_10 - 0.00029 21.2 0.0 0.027 14.8 0.0 2.4 1 1 0 1 1 1 1 GAF domain HAD_2 PF13419.6 AAAP01003814.1_11 - 4.8e-11 43.1 0.0 1.9e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003814.1_11 - 1.2e-08 35.5 0.0 6.6e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003814.1_11 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAAP01003814.1_11 - 0.00099 19.6 0.1 0.0014 19.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3293 PF11697.8 AAAP01003814.1_15 - 0.022 15.2 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) DUF3394 PF11874.8 AAAP01003814.1_15 - 0.13 11.9 0.8 0.14 11.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) HATPase_c PF02518.26 AAAP01003815.1_1 - 1.3e-13 51.4 0.0 2.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 AAAP01003815.1_1 - 4.1e-09 37.2 0.6 1e-08 35.8 0.2 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AAAP01003815.1_1 - 9.5e-09 35.7 0.2 3.5e-08 33.8 0.2 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAAP01003815.1_1 - 0.0006 20.2 0.1 0.0013 19.0 0.1 1.7 1 0 0 1 1 1 1 GAF domain Hpt PF01627.23 AAAP01003815.1_1 - 0.0013 19.0 3.7 0.0049 17.1 0.0 3.0 3 0 0 3 3 3 1 Hpt domain HATPase_c_2 PF13581.6 AAAP01003815.1_1 - 0.022 14.7 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003815.1_1 - 0.11 12.3 0.0 0.34 10.8 0.1 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003815.1_2 - 3.2e-28 98.1 0.2 5.7e-28 97.3 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CheX PF13690.6 AAAP01003815.1_2 - 6.3e-14 51.9 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX GGDEF PF00990.21 AAAP01003815.1_3 - 1e-43 148.9 0.0 1.6e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF1905 PF08922.11 AAAP01003815.1_3 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1905) Acyl_transf_1 PF00698.21 AAAP01003815.1_3 - 0.045 13.3 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Acyl transferase domain PAS_8 PF13188.7 AAAP01003815.1_3 - 0.061 13.4 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 PAS domain AAA_16 PF13191.6 AAAP01003815.1_3 - 0.1 13.0 0.8 0.18 12.2 0.3 1.8 2 0 0 2 2 2 0 AAA ATPase domain UPF0126 PF03458.13 AAAP01003815.1_4 - 1.4e-36 124.2 27.3 2.6e-19 68.9 6.6 2.5 3 0 0 3 3 3 2 UPF0126 domain NADH5_C PF06455.11 AAAP01003815.1_4 - 0.26 10.9 1.7 0.35 10.4 0.9 1.7 1 1 1 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus Oxidored_q6 PF01058.22 AAAP01003815.1_5 - 1.6e-30 105.6 0.0 2.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 AAAP01003815.1_5 - 1.7e-17 63.5 8.4 2.2e-17 63.2 6.5 2.0 2 0 0 2 2 2 1 NiFe/NiFeSe hydrogenase small subunit C-terminal NiFeSe_Hases PF00374.19 AAAP01003815.1_6 - 4.7e-67 227.0 0.0 5.8e-50 170.6 0.0 2.8 2 1 0 2 2 2 2 Nickel-dependent hydrogenase OprF PF05736.11 AAAP01003815.1_7 - 0.12 12.1 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 OprF membrane domain Chlam_OMP3 PF03503.13 AAAP01003815.1_7 - 0.26 11.6 4.1 3.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 DUF4431 PF14485.6 AAAP01003815.1_8 - 0.0055 16.5 0.2 13 5.6 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4431) Cytochrome_C7 PF14522.6 AAAP01003815.1_10 - 2e-07 30.9 12.4 0.0039 17.2 8.5 3.3 1 1 2 3 3 3 3 Cytochrome c7 and related cytochrome c Cytochrome_C554 PF13435.6 AAAP01003815.1_10 - 3.1e-06 28.0 13.0 2.6e-05 25.0 3.2 4.0 1 1 4 5 5 5 1 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.6 AAAP01003815.1_10 - 0.0013 19.2 13.4 0.054 14.0 4.7 2.9 2 2 0 2 2 2 2 Cytochrome c3 Cytochrom_NNT PF03264.14 AAAP01003815.1_10 - 0.0078 15.9 11.4 0.1 12.3 1.4 3.1 1 1 1 3 3 3 3 NapC/NirT cytochrome c family, N-terminal region C1_1 PF00130.22 AAAP01003815.1_10 - 0.037 13.9 1.4 2.1 8.3 0.0 2.9 3 2 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Paired_CXXCH_1 PF09699.10 AAAP01003815.1_10 - 0.19 11.5 22.4 3.6 7.4 1.9 4.6 1 1 3 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_CIII PF02085.16 AAAP01003815.1_10 - 0.32 11.3 11.9 9.4 6.6 0.5 3.3 2 1 0 2 2 2 0 Class III cytochrome C family Cytochrom_C552 PF02335.15 AAAP01003815.1_10 - 3.8 6.3 8.8 1.6 7.6 0.2 2.9 2 1 1 3 3 3 0 Cytochrome c552 4HB_MCP_1 PF12729.7 AAAP01003815.1_11 - 8.4e-16 58.0 0.0 5.8e-14 52.0 0.0 2.2 1 1 1 2 2 2 2 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003815.1_11 - 5.8e-09 36.2 0.8 3.3e-08 33.8 0.2 2.6 2 0 0 2 2 2 1 HAMP domain CHASE3 PF05227.13 AAAP01003815.1_11 - 0.0013 18.6 2.6 0.0089 15.9 0.1 2.4 2 0 0 2 2 2 1 CHASE3 domain HBM PF16591.5 AAAP01003815.1_11 - 0.0097 15.4 1.1 0.13 11.7 1.2 2.1 1 1 0 1 1 1 1 Helical bimodular sensor domain MCPsignal PF00015.21 AAAP01003815.1_12 - 5.8e-32 110.9 42.1 2.2e-31 109.0 27.5 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 AAAP01003815.1_12 - 3.1e-05 24.0 12.7 0.016 15.2 1.6 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003815.1_12 - 0.0012 19.1 25.0 0.24 11.7 4.2 4.5 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.14 AAAP01003815.1_12 - 0.0028 17.6 5.6 0.022 14.6 2.2 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Sec34 PF04136.15 AAAP01003815.1_12 - 0.0053 16.6 2.6 3.8 7.4 0.0 3.4 3 1 1 4 4 4 1 Sec34-like family Laminin_II PF06009.12 AAAP01003815.1_12 - 0.031 14.3 24.2 0.16 12.0 3.1 3.9 1 1 2 3 3 3 0 Laminin Domain II TMPIT PF07851.13 AAAP01003815.1_12 - 0.088 12.0 3.3 3.2 6.9 1.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein CorA PF01544.18 AAAP01003815.1_12 - 0.12 11.7 4.4 1.6 8.0 1.6 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein GldM_N PF12081.8 AAAP01003815.1_12 - 0.14 12.3 0.3 0.14 12.3 0.3 3.3 1 1 1 3 3 3 0 GldM N-terminal domain LXG PF04740.12 AAAP01003815.1_12 - 0.19 11.4 16.6 0.86 9.3 5.4 3.3 1 1 1 2 2 2 0 LXG domain of WXG superfamily ADIP PF11559.8 AAAP01003815.1_12 - 0.22 11.6 11.5 0.38 10.8 3.2 2.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Vps51 PF08700.11 AAAP01003815.1_12 - 0.71 10.0 6.4 24 5.1 0.1 3.9 2 2 1 3 3 3 0 Vps51/Vps67 SlyX PF04102.12 AAAP01003815.1_12 - 0.72 10.5 10.3 8 7.2 0.0 4.1 4 1 1 5 5 4 0 SlyX COG6 PF06419.11 AAAP01003815.1_12 - 1 7.5 8.2 0.14 10.3 0.5 2.3 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 COG5 PF10392.9 AAAP01003815.1_12 - 1.2 9.4 4.7 2.1 8.5 1.1 2.7 1 1 2 3 3 3 0 Golgi transport complex subunit 5 AATF-Che1 PF13339.6 AAAP01003815.1_12 - 1.3 9.7 6.4 71 4.1 6.3 2.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2774 PF11242.8 AAAP01003815.1_12 - 1.4 9.1 3.7 1.9 8.8 0.1 2.9 3 1 1 4 4 3 0 Protein of unknown function (DUF2774) MIP-T3_C PF17749.1 AAAP01003815.1_12 - 2.3 8.2 11.7 2.8 7.9 0.9 3.4 2 2 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Pox_RNA_Pol_19 PF05320.12 AAAP01003815.1_12 - 2.6 8.0 5.7 1.6 8.7 0.9 2.6 2 2 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF5631 PF18645.1 AAAP01003815.1_12 - 2.8 8.4 11.3 8.9 6.8 0.3 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5631) TPR_MLP1_2 PF07926.12 AAAP01003815.1_12 - 4.6 7.3 21.1 2.6 8.1 6.8 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 AAAP01003815.1_12 - 4.8 7.9 16.1 2.6 8.8 2.3 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 AAAP01003815.1_12 - 5.7 7.0 12.1 5.7 7.0 1.6 3.7 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 AAAP01003815.1_12 - 7.6 5.8 24.8 0.53 9.5 3.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 AAAP01003815.1_12 - 7.8 6.3 6.8 4.2 7.2 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1223 PF06764.11 AAAP01003815.1_13 - 1.6e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) LysR_substrate PF03466.20 AAAP01003815.1_14 - 9e-38 129.7 8.4 1.3e-37 129.2 8.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003815.1_14 - 1.5e-19 69.7 0.3 3.3e-19 68.6 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CMD PF02627.20 AAAP01003815.1_15 - 1.5e-11 44.2 6.2 2.7e-11 43.4 2.3 2.1 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family DUF2710 PF10921.8 AAAP01003815.1_15 - 0.062 13.7 0.1 0.086 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) Ribosomal_L35Ae PF01247.18 AAAP01003815.1_15 - 0.19 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L35Ae Putative_PNPOx PF01243.20 AAAP01003815.1_16 - 1.6e-14 53.8 0.0 3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sigma70_r4_2 PF08281.12 AAAP01003815.1_17 - 2.9e-13 49.3 0.6 5.9e-13 48.3 0.6 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAAP01003815.1_17 - 1.1e-11 44.3 1.0 2e-11 43.5 1.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAAP01003815.1_17 - 5.3e-07 29.0 2.3 5.7e-07 29.0 0.5 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAAP01003815.1_17 - 0.017 15.0 0.2 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 ECF sigma factor NrsF PF06532.11 AAAP01003815.1_18 - 1.4e-31 109.8 25.0 1.6e-31 109.6 25.0 1.0 1 0 0 1 1 1 1 Negative regulator of sigma F BiPBP_C PF06832.12 AAAP01003815.1_19 - 3.2e-14 52.7 3.5 8.2e-12 45.0 0.6 2.8 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family VWA_2 PF13519.6 AAAP01003816.1_1 - 1.6e-07 31.9 0.0 2.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AAAP01003816.1_1 - 2.9e-05 24.4 0.0 3.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AAAP01003816.1_1 - 0.00071 19.0 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Topoisom_I_N PF02919.15 AAAP01003816.1_2 - 0.16 11.4 2.2 0.22 11.0 2.2 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TPX2 PF06886.11 AAAP01003816.1_2 - 3.9 7.8 10.8 90 3.4 8.1 2.7 2 1 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Terminase_GpA PF05876.12 AAAP01003816.1_4 - 8e-196 651.9 0.0 1e-195 651.5 0.0 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) SHR3_chaperone PF08229.11 AAAP01003816.1_4 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 KAAG1 PF15354.6 AAAP01003816.1_4 - 0.21 12.2 0.1 0.21 12.2 0.1 2.5 2 0 0 2 2 2 0 Kidney-associated antigen 1 MarR_2 PF12802.7 AAAP01003816.1_5 - 0.0044 16.9 0.2 2 8.4 0.0 2.4 2 0 0 2 2 2 2 MarR family KORA PF16509.5 AAAP01003816.1_5 - 0.02 15.2 0.0 0.09 13.1 0.0 2.0 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Prim-Pol PF09250.11 AAAP01003816.1_7 - 9.3e-38 130.1 0.1 1.6e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal PriCT_1 PF08708.11 AAAP01003816.1_7 - 4.3e-15 55.2 0.0 1e-14 54.0 0.0 1.6 2 0 0 2 2 2 1 Primase C terminal 1 (PriCT-1) tRNA-synt_His PF13393.6 AAAP01003816.1_8 - 0.049 12.9 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HTH_17 PF12728.7 AAAP01003816.1_10 - 0.087 13.0 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_integrase PF00589.22 AAAP01003816.1_12 - 1.9e-27 96.1 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 AAAP01003816.1_12 - 5.9e-16 58.6 0.1 5.9e-16 58.6 0.1 1.9 2 0 0 2 2 2 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 AAAP01003816.1_12 - 0.029 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_4 PF14657.6 AAAP01003816.1_13 - 0.11 12.2 2.4 0.13 12.0 0.5 2.0 2 0 0 2 2 2 0 Arm DNA-binding domain ADP_ribosyl_GH PF03747.14 AAAP01003816.1_14 - 0.00032 20.5 0.2 0.0015 18.3 0.2 1.8 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase WYL PF13280.6 AAAP01003816.1_15 - 4.7e-34 117.9 0.4 5.6e-34 117.7 0.4 1.0 1 0 0 1 1 1 1 WYL domain Tubulin PF00091.25 AAAP01003816.1_16 - 3.7e-33 115.4 0.1 6.4e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AAAP01003816.1_16 - 1.6e-23 82.8 0.1 3.7e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 FtsZ family, C-terminal domain ADP_ribosyl_GH PF03747.14 AAAP01003816.1_17 - 2.2e-06 27.6 0.3 2.2e-06 27.6 0.3 2.0 1 1 1 2 2 2 1 ADP-ribosylglycohydrolase LpxC PF03331.13 AAAP01003817.1_2 - 7.9e-104 346.9 0.0 9.1e-104 346.7 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase FtsZ_C PF12327.8 AAAP01003817.1_4 - 3.6e-40 136.2 2.0 3.6e-40 136.2 2.0 1.9 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin PF00091.25 AAAP01003817.1_4 - 3.1e-29 102.6 0.1 5e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 AAAP01003817.1_4 - 0.0091 15.2 1.9 0.017 14.3 1.9 1.4 1 0 0 1 1 1 1 Tubulin like Rib_recp_KP_reg PF05104.12 AAAP01003817.1_4 - 0.93 10.5 15.0 1.5 9.9 15.0 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region FtsA PF14450.6 AAAP01003817.1_5 - 2.5e-32 111.3 0.5 2.2e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AAAP01003817.1_5 - 3.5e-25 88.2 0.6 2.6e-24 85.4 0.4 2.3 2 0 0 2 2 2 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 AAAP01003817.1_5 - 1.6e-10 40.3 0.9 1.7e-08 33.7 0.2 2.3 2 0 0 2 2 2 2 MreB/Mbl protein EutA PF06277.11 AAAP01003817.1_5 - 1.6e-06 27.2 1.3 2.3e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 AAAP01003817.1_5 - 0.0011 18.1 0.1 0.048 12.7 0.0 2.6 3 0 0 3 3 3 1 Type IV pilus assembly protein PilM; HSP70 PF00012.20 AAAP01003817.1_5 - 0.0035 15.6 0.2 0.075 11.2 0.0 2.2 2 0 0 2 2 2 1 Hsp70 protein FtsQ PF03799.15 AAAP01003817.1_6 - 1.1e-14 55.3 0.2 1.3e-14 55.0 0.2 1.1 1 0 0 1 1 1 1 Cell division protein FtsQ Dala_Dala_lig_C PF07478.13 AAAP01003817.1_7 - 7e-40 136.7 0.0 9.6e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AAAP01003817.1_7 - 1.4e-20 73.6 0.1 7.3e-20 71.3 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus B12-binding PF02310.19 AAAP01003817.1_7 - 2.5e-07 30.8 0.1 9.4e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 B12 binding domain ATP-grasp_3 PF02655.14 AAAP01003817.1_7 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AAAP01003817.1_7 - 0.00071 19.2 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AAAP01003817.1_7 - 0.012 15.3 0.0 0.043 13.6 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 AAAP01003817.1_7 - 0.031 13.9 0.0 0.062 12.9 0.0 1.4 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 AAAP01003817.1_7 - 0.062 12.8 0.0 8.5 5.8 0.0 3.0 3 0 0 3 3 3 0 ATP-grasp domain NAD_binding_8 PF13450.6 AAAP01003817.1_7 - 0.067 13.4 0.1 0.34 11.2 0.0 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain MurB_C PF02873.16 AAAP01003817.1_8 - 1.2e-28 99.6 0.1 3.9e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 AAAP01003817.1_8 - 2.2e-18 66.4 3.4 3.5e-17 62.5 2.3 2.1 2 0 0 2 2 2 2 FAD binding domain Mur_ligase PF01225.25 AAAP01003817.1_9 - 3.5e-30 104.2 0.9 1.2e-29 102.5 0.6 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 AAAP01003817.1_9 - 1.3e-27 97.1 0.1 1.8e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAAP01003817.1_9 - 2e-21 76.1 0.3 9.8e-21 73.8 0.0 2.4 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Glyco_tran_28_C PF04101.16 AAAP01003817.1_10 - 3.2e-35 121.6 0.0 4.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 AAAP01003817.1_10 - 8.5e-30 103.6 0.5 2e-29 102.4 0.8 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.6 AAAP01003817.1_10 - 0.016 15.6 1.5 0.016 15.6 1.5 1.9 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain FTSW_RODA_SPOVE PF01098.19 AAAP01003817.1_11 - 8.9e-78 261.8 21.8 1e-77 261.6 21.8 1.0 1 0 0 1 1 1 1 Cell cycle protein Mur_ligase_M PF08245.12 AAAP01003817.1_12 - 4.6e-27 95.3 0.0 8.4e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAAP01003817.1_12 - 7.1e-05 23.0 0.0 0.00025 21.3 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain 2-Hacid_dh_C PF02826.19 AAAP01003817.1_12 - 0.00026 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAAP01003817.1_12 - 0.0014 19.1 0.0 0.0043 17.5 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Peptidase_M17_N PF02789.17 AAAP01003817.1_12 - 0.043 13.7 0.3 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Peripla_BP_4 PF13407.6 AAAP01003817.1_12 - 0.048 13.2 0.0 2.9 7.4 0.0 2.5 3 0 0 3 3 3 0 Periplasmic binding protein domain CbiA PF01656.23 AAAP01003817.1_12 - 0.32 11.1 2.9 0.31 11.1 1.2 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glycos_transf_4 PF00953.21 AAAP01003817.1_13 - 2.1e-35 122.1 13.5 2.1e-35 122.1 13.5 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 AAAP01003817.1_13 - 0.0016 17.9 5.2 0.0047 16.4 5.2 1.9 1 0 0 1 1 1 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 YtpI PF14007.6 AAAP01003817.1_13 - 2.2 8.5 0.0 2.2 8.5 0.0 3.5 4 0 0 4 4 4 0 YtpI-like protein Mur_ligase_M PF08245.12 AAAP01003817.1_14 - 5.6e-39 134.1 0.0 7.9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAAP01003817.1_14 - 3.2e-11 43.3 0.1 7.3e-10 39.0 0.0 2.8 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AAAP01003817.1_14 - 7.5e-10 39.0 0.1 2.3e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 AAAP01003817.1_15 - 1.2e-49 168.9 0.0 1.7e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAAP01003817.1_15 - 9.2e-23 80.3 0.1 5e-21 74.8 0.0 2.7 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AAAP01003817.1_15 - 3.8e-12 46.4 0.1 1.7e-10 41.1 0.0 2.9 2 0 0 2 2 2 1 Mur ligase family, catalytic domain RraA-like PF03737.15 AAAP01003817.1_15 - 0.034 14.3 0.1 1.7 8.8 0.1 2.8 2 1 0 2 2 2 0 Aldolase/RraA YCII PF03795.14 AAAP01003817.1_15 - 0.093 13.2 1.9 0.16 12.4 0.1 2.3 3 0 0 3 3 3 0 YCII-related domain Transpeptidase PF00905.22 AAAP01003817.1_16 - 1.3e-59 202.0 0.0 1.7e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAAP01003817.1_16 - 1.3e-11 45.2 0.0 3.1e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain DUF1522 PF07482.11 AAAP01003817.1_18 - 0.12 12.7 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) AIRS_C PF02769.22 AAAP01003818.1_1 - 2.6e-52 177.1 6.5 3.9e-33 114.8 0.5 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAAP01003818.1_1 - 1.2e-47 160.5 4.7 3.3e-23 82.2 0.5 2.5 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 AAAP01003818.1_1 - 5.2e-14 52.5 0.0 1.3e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_5 PF13507.6 AAAP01003818.1_2 - 4.1e-40 137.5 0.0 5.3e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 AAAP01003818.1_2 - 4.3e-08 33.0 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AAAP01003818.1_2 - 9.3e-08 32.0 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 AAAP01003818.1_2 - 0.0012 18.6 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Glucokinase PF02685.16 AAAP01003818.1_4 - 2e-107 358.9 0.2 2.2e-107 358.7 0.2 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 AAAP01003818.1_4 - 0.073 12.5 0.1 11 5.4 0.0 2.3 2 1 0 2 2 2 0 ROK family Glyco_transf_5 PF08323.11 AAAP01003818.1_5 - 1.9e-78 263.5 0.0 3.2e-78 262.8 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AAAP01003818.1_5 - 3.1e-12 46.4 0.0 4.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003818.1_5 - 1.6e-09 38.4 1.4 5.2e-09 36.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AAAP01003818.1_5 - 5.5e-09 36.6 0.1 8.7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003818.1_5 - 5.8e-06 26.4 0.5 1.5e-05 25.1 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 NTP_transferase PF00483.23 AAAP01003818.1_6 - 1.7e-65 221.1 0.0 2.1e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003818.1_6 - 6.1e-08 33.2 0.0 1.3e-07 32.1 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep PF00132.24 AAAP01003818.1_6 - 0.012 15.4 6.6 0.071 12.9 0.3 3.0 2 1 1 3 3 3 0 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 AAAP01003818.1_6 - 0.039 12.9 0.0 0.24 10.3 0.0 1.9 2 0 0 2 2 2 0 L-fucokinase dCache_2 PF08269.11 AAAP01003818.1_7 - 3.7e-75 252.8 0.0 1.1e-74 251.3 0.0 1.7 2 0 0 2 2 2 1 Cache domain sCache_2 PF17200.4 AAAP01003818.1_7 - 3.6e-58 195.8 0.0 4.5e-36 124.0 0.0 3.0 1 1 2 3 3 3 2 Single Cache domain 2 Cache_3-Cache_2 PF17201.4 AAAP01003818.1_7 - 3.5e-24 85.6 0.1 4e-12 46.0 0.0 3.2 2 1 1 3 3 3 2 Cache 3/Cache 2 fusion domain HATPase_c PF02518.26 AAAP01003818.1_7 - 1.1e-21 77.4 0.0 2.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003818.1_7 - 9.4e-10 38.4 3.7 4.1e-09 36.4 0.0 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain N_formyltrans_C PF18216.1 AAAP01003818.1_7 - 0.0029 17.2 0.0 0.076 12.7 0.0 2.5 2 0 0 2 2 2 1 N-formyltransferase dimerization C-terminal domain FtsX PF02687.21 AAAP01003818.1_7 - 0.063 13.7 0.0 7.8 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsX-like permease family HATPase_c_5 PF14501.6 AAAP01003818.1_7 - 0.091 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 GHKL domain ComFB PF10719.9 AAAP01003818.1_7 - 0.11 12.6 1.3 0.95 9.6 0.1 2.5 1 1 1 2 2 2 0 Late competence development protein ComFB Halogen_Hydrol PF10112.9 AAAP01003818.1_7 - 0.22 11.5 3.0 0.3 11.1 1.1 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MCPsignal PF00015.21 AAAP01003818.1_8 - 1.4e-30 106.4 38.3 4.6e-30 104.7 19.2 3.8 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 AAAP01003818.1_8 - 0.00075 19.5 4.5 0.21 11.6 0.1 4.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) HAMP PF00672.25 AAAP01003818.1_8 - 0.001 19.4 1.2 0.005 17.2 0.0 2.9 3 0 0 3 3 3 1 HAMP domain DUF948 PF06103.11 AAAP01003818.1_8 - 0.049 13.9 0.6 0.049 13.9 0.6 4.8 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3965 PF13112.6 AAAP01003818.1_8 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) Seryl_tRNA_N PF02403.22 AAAP01003818.1_8 - 3.8 7.8 5.5 8.8 6.6 0.2 3.6 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain PilJ PF13675.6 AAAP01003818.1_8 - 4.3 7.4 7.5 6.5 6.8 0.2 3.6 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term STAS_2 PF13466.6 AAAP01003818.1_9 - 1.6e-15 57.2 0.1 1.8e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003818.1_9 - 3e-10 39.8 0.0 3.1e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 STAS domain Peptidase_C25_C PF03785.14 AAAP01003818.1_9 - 0.039 13.8 0.1 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Response_reg PF00072.24 AAAP01003818.1_10 - 8.1e-16 58.2 0.0 9.2e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AAAP01003818.1_11 - 6.2e-31 106.9 0.2 2e-25 89.1 0.2 2.4 2 0 0 2 2 2 2 Response regulator receiver domain SpoIIE PF07228.12 AAAP01003818.1_11 - 3e-23 82.8 0.2 4.8e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 AAAP01003818.1_11 - 4.4e-12 46.0 0.0 9.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain TetR_C_15 PF17918.1 AAAP01003818.1_11 - 0.91 10.3 6.8 1.3 9.8 0.8 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain LysR_substrate PF03466.20 AAAP01003818.1_12 - 1e-37 129.5 4.7 1.5e-37 129.0 4.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003818.1_12 - 4.8e-18 64.9 0.7 1.2e-17 63.6 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Fumerase PF05681.14 AAAP01003818.1_13 - 3.1e-74 249.8 0.0 3.6e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) DUF3420 PF11900.8 AAAP01003818.1_13 - 0.036 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Fumerase_C PF05683.12 AAAP01003818.1_14 - 1.1e-26 93.4 0.1 1.3e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Fumarase C-terminus Tox-MPTase4 PF15640.6 AAAP01003818.1_14 - 0.033 14.1 0.0 5.1 7.0 0.0 2.0 1 1 1 2 2 2 0 Metallopeptidase toxin 4 AAA_3 PF07726.11 AAAP01003818.1_14 - 0.17 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 AAAP01003818.1_15 - 3.5e-48 164.3 45.1 3.5e-48 164.3 45.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01003818.1_15 - 1e-05 25.0 34.9 0.0023 17.3 12.0 2.0 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAAP01003818.1_15 - 7.2e-05 21.8 18.7 0.01 14.7 0.1 3.4 3 1 0 3 3 3 3 MFS_1 like family ATG22 PF11700.8 AAAP01003818.1_15 - 0.018 13.7 14.9 0.028 13.1 0.1 3.0 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like HAD_2 PF13419.6 AAAP01003818.1_16 - 2.5e-10 40.7 0.0 3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003818.1_16 - 3.7e-05 23.7 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AAAP01003818.1_16 - 0.00016 22.1 0.0 0.00029 21.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Iso_dh PF00180.20 AAAP01003818.1_17 - 3.5e-85 286.2 0.0 3.9e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4147 PF13660.6 AAAP01003818.1_18 - 2.1e-84 282.6 1.9 4e-84 281.7 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AAAP01003818.1_18 - 3.6e-35 120.5 0.3 3.6e-35 120.5 0.3 1.8 2 0 0 2 2 2 1 MOFRL family PK PF00224.21 AAAP01003818.1_19 - 1.1e-113 379.7 0.0 1.6e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AAAP01003818.1_19 - 1.3e-28 99.6 1.1 3.6e-28 98.1 1.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 AAAP01003818.1_19 - 0.0028 16.7 0.0 0.072 12.1 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain HpcH_HpaI PF03328.14 AAAP01003818.1_19 - 0.02 14.0 0.4 0.2 10.8 0.1 2.5 2 1 1 3 3 3 0 HpcH/HpaI aldolase/citrate lyase family DUF4253 PF14062.6 AAAP01003818.1_19 - 0.049 13.8 0.1 6.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) YceG PF02618.16 AAAP01003818.1_20 - 1e-80 271.2 0.0 1.2e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 YceG-like family DUF4747 PF15931.5 AAAP01003819.1_2 - 9.6e-49 166.3 0.0 1.1e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4747) DNA_gyraseB PF00204.25 AAAP01003819.1_3 - 6.1e-46 156.1 0.0 8.8e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 AAAP01003819.1_3 - 3.6e-20 72.5 0.0 7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AAAP01003819.1_3 - 3.5e-17 62.5 0.0 6.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AAAP01003819.1_3 - 0.026 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003819.1_3 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain 4HBT PF03061.22 AAAP01003819.1_4 - 2.4e-18 66.2 2.2 3.1e-18 65.9 1.0 1.7 1 1 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 AAAP01003819.1_4 - 0.00016 22.0 0.3 0.00018 21.8 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 AAAP01003819.1_4 - 0.002 18.6 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydrat_N PF13452.6 AAAP01003819.1_4 - 0.0092 16.1 0.0 0.021 15.0 0.0 1.7 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase SSB PF00436.25 AAAP01003819.1_5 - 6.6e-39 132.1 1.0 8.2e-39 131.8 1.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family LPAM_1 PF08139.12 AAAP01003819.1_7 - 5e-06 26.7 3.0 6.5e-06 26.3 3.0 1.2 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site LPAM_2 PF13627.6 AAAP01003819.1_7 - 2 8.3 6.0 2.8 7.9 6.0 1.2 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Guanylate_cyc PF00211.20 AAAP01003819.1_8 - 2.2e-13 50.2 0.0 3.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_53 PF18606.1 AAAP01003819.1_8 - 0.034 13.8 0.5 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain DNA_ligase_A_C PF04679.15 AAAP01003819.1_8 - 0.052 14.2 0.0 21 5.8 0.0 3.1 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region TPR_19 PF14559.6 AAAP01003819.1_8 - 0.067 13.7 5.6 0.24 11.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1641 PF07849.11 AAAP01003819.1_8 - 0.18 11.7 0.4 0.98 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) HATPase_c PF02518.26 AAAP01003819.1_9 - 4.7e-24 85.1 0.0 9.2e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003819.1_9 - 2.1e-07 30.9 0.6 6.9e-07 29.2 0.6 2.0 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003819.1_9 - 8.5e-06 26.1 1.1 8.5e-06 26.1 1.1 2.2 3 0 0 3 3 3 1 HAMP domain HATPase_c_3 PF13589.6 AAAP01003819.1_9 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Trehalase_Ca-bi PF07492.11 AAAP01003819.1_9 - 0.18 11.5 0.4 0.39 10.5 0.4 1.5 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain Trp_oprn_chp PF09534.10 AAAP01003819.1_9 - 1 9.1 9.5 0.61 9.9 3.0 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Response_reg PF00072.24 AAAP01003819.1_10 - 2e-31 108.4 0.2 2.7e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003819.1_10 - 5.9e-21 74.3 0.0 1.4e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HisG PF01634.18 AAAP01003819.1_11 - 3.6e-44 150.5 0.0 4.5e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Aminotran_MocR PF12897.7 AAAP01003819.1_11 - 0.05 12.4 0.1 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Histidinol_dh PF00815.20 AAAP01003819.1_12 - 8.7e-170 565.1 0.1 9.8e-170 565.0 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase UPF0262 PF06793.12 AAAP01003819.1_13 - 8.7e-69 230.5 0.1 9.8e-69 230.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) LMWPc PF01451.21 AAAP01003819.1_14 - 1.1e-17 64.8 0.0 1.3e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase eIF-1a PF01176.19 AAAP01003819.1_15 - 6.5e-28 96.3 0.0 7.2e-28 96.2 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 AAAP01003819.1_15 - 0.00062 19.5 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 AAAP01003819.1_15 - 0.0072 16.7 0.0 0.009 16.3 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNase_II_C_S1 PF18614.1 AAAP01003819.1_15 - 0.02 14.8 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Maf PF02545.14 AAAP01003819.1_16 - 7.8e-51 172.2 0.0 8.7e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Crp PF00325.20 AAAP01003819.1_16 - 0.033 13.8 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family RNase_E_G PF10150.9 AAAP01003819.1_17 - 5.7e-34 117.8 0.0 7.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family DUF3117 PF11314.8 AAAP01003819.1_17 - 0.043 13.6 0.0 0.28 11.0 0.0 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) YacG PF03884.14 AAAP01003819.1_18 - 3.9e-15 55.3 0.7 5.4e-15 54.9 0.7 1.2 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG zf-C6H2 PF15801.5 AAAP01003819.1_18 - 0.0078 16.5 0.3 0.0097 16.2 0.3 1.1 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DUF2116 PF09889.9 AAAP01003819.1_18 - 0.027 14.5 0.2 0.031 14.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ZZ PF00569.17 AAAP01003819.1_18 - 0.032 14.1 0.6 0.045 13.6 0.6 1.2 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-Di19 PF05605.12 AAAP01003819.1_18 - 0.049 13.9 1.7 0.77 10.1 0.3 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-HIT PF04438.16 AAAP01003819.1_18 - 0.71 9.8 5.6 9.1 6.3 5.6 2.0 1 1 0 1 1 1 0 HIT zinc finger CoA_transf_3 PF02515.17 AAAP01003819.1_19 - 1.3e-94 317.4 0.0 1.5e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III TetR_C_24 PF17932.1 AAAP01003819.1_20 - 1.9e-18 66.8 0.0 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAAP01003819.1_20 - 2.6e-15 55.9 0.1 5.1e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 AAAP01003819.1_20 - 0.099 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase UPF0122 PF04297.14 AAAP01003819.1_20 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Cut12 PF11500.8 AAAP01003819.1_20 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.12 AAAP01003819.1_20 - 0.44 10.5 3.6 1 9.3 3.6 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AMP-binding_C_2 PF14535.6 AAAP01003819.1_21 - 2.3e-15 56.7 0.2 4.1e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AAAP01003819.1_21 - 2.4e-13 49.5 1.6 2.4e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Peripla_BP_6 PF13458.6 AAAP01003819.1_22 - 1.3e-18 67.8 0.3 1.7e-18 67.4 0.3 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003819.1_22 - 7e-13 48.3 0.0 8e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003819.1_22 - 0.00073 18.7 0.0 0.00099 18.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2415 PF10313.9 AAAP01003820.1_1 - 0.052 13.5 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) SCO1-SenC PF02630.14 AAAP01003820.1_2 - 3.4e-43 146.8 0.0 4.2e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAAP01003820.1_2 - 0.00033 20.6 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family dCache_1 PF02743.18 AAAP01003820.1_2 - 0.074 12.8 0.0 4.9 6.9 0.0 2.7 2 1 0 3 3 3 0 Cache domain Redoxin PF08534.10 AAAP01003820.1_3 - 2.1e-13 50.3 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01003820.1_3 - 2.9e-12 46.6 0.0 5.2e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAAP01003820.1_3 - 1.4e-09 38.2 0.0 2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AAAP01003820.1_3 - 3.4e-05 23.8 0.0 0.0043 17.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AAAP01003820.1_3 - 0.0022 18.4 0.0 0.0061 17.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AAAP01003820.1_3 - 0.03 14.5 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like PCuAC PF04314.13 AAAP01003820.1_4 - 1.5e-36 124.5 0.2 2.2e-36 123.9 0.2 1.3 1 0 0 1 1 1 1 Copper chaperone PCu(A)C DUF2946 PF11162.8 AAAP01003820.1_5 - 0.85 10.3 7.0 1.2 9.9 7.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Hemerythrin PF01814.23 AAAP01003820.1_6 - 5e-08 33.6 1.4 6.3e-08 33.3 1.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Flavoprotein PF02441.19 AAAP01003820.1_6 - 0.081 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Flavoprotein EAL PF00563.20 AAAP01003820.1_8 - 1.2e-65 221.3 0.0 1.7e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 EAL domain cNMP_binding PF00027.29 AAAP01003820.1_8 - 2.6e-21 75.5 0.1 1.1e-20 73.5 0.0 2.2 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain LexA_DNA_bind PF01726.16 AAAP01003820.1_8 - 0.065 13.0 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 LexA DNA binding domain DUF326 PF03860.16 AAAP01003820.1_9 - 0.45 10.6 38.0 0.091 12.8 13.6 3.6 5 0 0 5 5 5 0 Domain of Unknown Function (DUF326) cNMP_binding PF00027.29 AAAP01003820.1_10 - 1.9e-19 69.5 0.1 1.3e-10 41.2 0.0 3.4 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Hemerythrin PF01814.23 AAAP01003820.1_10 - 2.1e-12 47.8 3.3 4.3e-12 46.8 3.3 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactamase_B_2 PF12706.7 AAAP01003820.1_10 - 1.4e-11 44.3 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01003820.1_10 - 1.6e-07 31.5 0.7 3.9e-07 30.3 0.3 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PAS_7 PF12860.7 AAAP01003820.1_11 - 4.7e-81 268.5 0.8 5.5e-40 136.1 0.0 3.9 3 1 1 4 4 4 2 PAS fold HATPase_c PF02518.26 AAAP01003820.1_11 - 5.6e-23 81.6 0.0 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003820.1_11 - 5.3e-19 68.0 1.3 9e-18 64.1 0.0 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003820.1_11 - 1.4e-16 60.7 0.6 1.7e-07 31.5 0.1 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAAP01003820.1_11 - 2.3e-11 43.7 0.9 0.018 15.0 0.0 4.3 3 1 1 4 4 4 3 PAS fold PAS_9 PF13426.7 AAAP01003820.1_11 - 1e-09 38.6 0.1 3.8e-06 27.1 0.0 3.1 3 1 0 3 3 3 2 PAS domain PAS_8 PF13188.7 AAAP01003820.1_11 - 6.8e-07 29.2 1.1 0.017 15.1 0.1 3.7 3 0 0 3 3 3 2 PAS domain Ribosomal_L14 PF00238.19 AAAP01003820.1_11 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L14p/L23e Replicase PF03090.17 AAAP01003820.1_11 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Replicase family ANAPC5 PF12862.7 AAAP01003820.1_11 - 1 9.4 3.1 10 6.3 0.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Radical_SAM_N PF08497.10 AAAP01003820.1_12 - 5.1e-142 472.5 0.0 6.6e-142 472.1 0.0 1.1 1 0 0 1 1 1 1 Radical SAM N-terminal DUF3362 PF11842.8 AAAP01003820.1_12 - 4e-40 137.6 0.1 9.7e-40 136.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3362) Radical_SAM PF04055.21 AAAP01003820.1_12 - 3e-19 70.0 0.0 1.1e-18 68.2 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003820.1_12 - 0.0081 16.2 0.0 1.8 8.6 0.0 2.8 2 1 0 2 2 2 2 B12 binding domain Helitron_like_N PF14214.6 AAAP01003820.1_12 - 0.19 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus dCache_1 PF02743.18 AAAP01003820.1_13 - 6.4e-08 32.7 0.0 8.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Cache domain MMPL PF03176.15 AAAP01003820.1_15 - 1.4e-25 90.0 37.6 2.1e-17 63.1 16.7 2.9 2 1 0 2 2 2 2 MMPL family ACR_tran PF00873.19 AAAP01003820.1_15 - 0.04 11.6 26.5 0.011 13.4 12.1 2.4 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Patched PF02460.18 AAAP01003820.1_15 - 5.2 5.0 7.7 11 4.0 7.7 1.5 1 0 0 1 1 1 0 Patched family YdjC PF04794.12 AAAP01003820.1_16 - 1.3e-55 188.9 0.0 1.5e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein LPG_synthase_TM PF03706.13 AAAP01003820.1_17 - 9.2e-25 87.8 32.2 1.1e-24 87.5 32.2 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region PseudoU_synth_2 PF00849.22 AAAP01003820.1_18 - 1.9e-35 122.3 0.0 2.6e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAAP01003820.1_18 - 0.00021 20.9 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain HAMP_N3 PF18575.1 AAAP01003820.1_18 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 HAD_2 PF13419.6 AAAP01003820.1_19 - 3.7e-28 98.8 0.0 4.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003820.1_19 - 7.3e-19 68.9 0.1 2.9e-15 57.1 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003820.1_19 - 9.9e-12 44.8 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AAAP01003820.1_19 - 2.1e-11 44.6 0.0 3.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003820.1_19 - 4.9e-07 29.7 0.0 0.33 10.6 0.0 3.1 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase GntR PF00392.21 AAAP01003820.1_19 - 0.02 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Hydrolase_6 PF13344.6 AAAP01003820.1_19 - 0.023 14.8 0.0 10 6.3 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 AAAP01003820.1_19 - 0.066 12.9 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase PaaX PF07848.12 AAAP01003820.1_19 - 0.096 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein ADH_zinc_N PF00107.26 AAAP01003820.1_19 - 0.097 12.7 0.3 0.32 11.0 0.4 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Put_Phosphatase PF06888.12 AAAP01003820.1_19 - 0.12 11.8 0.0 10 5.4 0.0 2.6 2 1 1 3 3 3 0 Putative Phosphatase AsmA PF05170.14 AAAP01003820.1_20 - 4.5e-06 25.8 0.0 5.1e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 AsmA family AMP-binding_C_2 PF14535.6 AAAP01003821.1_1 - 0.00089 19.5 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 AAAP01003821.1_2 - 2.6e-154 514.1 1.9 3e-154 514.0 1.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAAP01003821.1_2 - 2.6e-05 23.8 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Wtap PF17098.5 AAAP01003821.1_2 - 0.036 14.0 0.1 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 WTAP/Mum2p family HPTransfase PF10090.9 AAAP01003821.1_2 - 0.21 11.4 2.9 5.5 6.8 0.3 2.7 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain Thiolase_N PF00108.23 AAAP01003821.1_3 - 5.8e-82 274.9 2.3 9.9e-82 274.2 2.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAAP01003821.1_3 - 6.3e-42 142.1 6.9 1.3e-41 141.1 1.6 2.9 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01003821.1_3 - 0.0045 16.6 5.8 0.11 12.0 0.9 3.5 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAAP01003821.1_4 - 2.2e-54 183.7 2.2 3.5e-54 183.1 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAAP01003821.1_4 - 4.8e-39 133.5 0.2 1.4e-38 132.1 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AAAP01003821.1_4 - 3.4e-30 105.0 1.2 6.7e-30 104.1 1.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003821.1_4 - 1e-26 92.9 0.0 1.8e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 AAAP01003821.1_4 - 0.0035 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AMP-binding_C PF13193.6 AAAP01003821.1_4 - 0.048 14.6 0.1 0.27 12.2 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Usp PF00582.26 AAAP01003821.1_5 - 2.2e-19 70.4 2.0 2.4e-11 44.3 0.2 2.3 2 1 0 2 2 2 2 Universal stress protein family 4HBT PF03061.22 AAAP01003821.1_6 - 4.9e-15 55.6 0.2 7.7e-15 55.0 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAAP01003821.1_6 - 4.2e-13 49.6 0.1 5.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAAP01003821.1_6 - 0.00098 19.4 0.3 0.0013 19.1 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily GGDEF PF00990.21 AAAP01003821.1_7 - 4.1e-52 176.2 0.0 6e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AAAP01003821.1_7 - 5e-06 26.7 0.0 1.6e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003821.1_7 - 6.9e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003821.1_7 - 0.0024 17.8 0.0 0.0094 16.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 AAAP01003821.1_7 - 0.1 12.9 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 GGDEF-like domain CMD PF02627.20 AAAP01003821.1_8 - 5.2e-14 52.1 0.1 7e-11 42.0 0.0 2.3 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family TAL_effector PF03377.13 AAAP01003821.1_8 - 0.031 14.6 0.2 1.9 8.9 0.0 2.8 2 0 0 2 2 2 0 TAL effector repeat PA26 PF04636.13 AAAP01003821.1_8 - 0.048 12.6 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) 5_nucleotid_C PF02872.18 AAAP01003821.1_9 - 6.3e-43 146.7 0.0 1.1e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 AAAP01003821.1_9 - 6.5e-10 39.8 0.0 9.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 AAAP01003821.1_9 - 0.0018 17.8 0.1 0.0044 16.5 0.1 1.5 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Metallophos_2 PF12850.7 AAAP01003821.1_9 - 0.02 15.1 0.0 0.056 13.6 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NmrA PF05368.13 AAAP01003821.1_9 - 0.12 11.9 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family HrpB2 PF09487.10 AAAP01003821.1_9 - 0.45 11.0 3.3 0.23 11.9 0.5 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Helicase_C_2 PF13307.6 AAAP01003821.1_10 - 1.3e-15 58.0 0.0 2.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 AAAP01003821.1_10 - 0.0049 16.6 0.0 0.1 12.4 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 AAAP01003821.1_10 - 0.022 14.8 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAAP01003821.1_10 - 0.098 13.0 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Hemerythrin PF01814.23 AAAP01003821.1_12 - 9.2e-15 55.4 5.4 1e-14 55.2 3.2 2.1 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain CRS1_YhbY PF01985.21 AAAP01003821.1_12 - 0.022 14.9 0.4 0.058 13.6 0.4 1.7 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain CAP_N PF01213.19 AAAP01003821.1_12 - 0.064 12.7 1.1 0.12 11.9 0.6 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TetR_C_15 PF17918.1 AAAP01003821.1_12 - 0.14 12.9 4.5 0.49 11.2 0.5 3.4 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain tRNA-synt_1f PF01921.18 AAAP01003821.1_13 - 1.9e-134 448.2 0.0 2.2e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 AAAP01003821.1_13 - 0.0044 15.3 0.0 0.0061 14.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AAAP01003821.1_13 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1b PF00579.25 AAAP01003821.1_13 - 0.13 11.6 0.1 0.91 8.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Cupin_2 PF07883.11 AAAP01003821.1_14 - 5.9e-09 35.5 0.1 7.4e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AAAP01003821.1_14 - 0.00026 20.9 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 AAAP01003821.1_14 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 AAAP01003821.1_14 - 0.0015 18.3 0.1 0.0016 18.2 0.1 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.14 AAAP01003821.1_14 - 0.0067 16.6 0.0 0.0089 16.2 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding_2 PF14525.6 AAAP01003821.1_14 - 0.051 13.3 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 AraC-binding-like domain DUF4087 PF13316.6 AAAP01003821.1_14 - 0.055 14.0 0.1 0.076 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) MannoseP_isomer PF01050.18 AAAP01003821.1_14 - 0.057 13.3 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase G3P_acyltransf PF02660.15 AAAP01003821.1_15 - 1.2e-47 162.0 15.3 1.4e-47 161.8 15.3 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase Amidohydro_1 PF01979.20 AAAP01003821.1_16 - 1.4e-21 77.2 0.2 2e-21 76.7 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AAAP01003821.1_16 - 4.1e-11 43.0 1.2 9.6e-09 35.2 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family DHOase PF12890.7 AAAP01003821.1_16 - 1.2e-07 31.8 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Dihydro-orotase-like OTCace PF00185.24 AAAP01003821.1_17 - 2.2e-14 53.9 0.0 2.5e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Hemerythrin PF01814.23 AAAP01003822.1_2 - 3.2e-07 31.0 4.3 4.3e-07 30.6 4.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Peptidase_M24 PF00557.24 AAAP01003822.1_3 - 2.5e-34 118.8 0.0 3.1e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 AAAP01003822.1_3 - 1.6e-23 82.5 0.0 2.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N_2 PF16189.5 AAAP01003822.1_4 - 1.6e-24 86.8 0.0 1.2e-23 84.0 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 AAAP01003822.1_4 - 1.1e-17 64.9 0.0 1.8e-13 51.3 0.0 2.2 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 AAAP01003822.1_4 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 UbiA PF01040.18 AAAP01003822.1_6 - 7.3e-47 159.8 38.6 1e-46 159.3 38.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2374 PF09574.10 AAAP01003822.1_6 - 0.72 9.7 0.0 0.72 9.7 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (Duf2374) DUF420 PF04238.12 AAAP01003822.1_7 - 1.2e-41 142.0 10.5 1.4e-41 141.9 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF420) DUF2306 PF10067.9 AAAP01003822.1_7 - 5.9e-05 23.3 8.0 0.0025 18.0 0.4 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2306) Spore_YhaL PF14147.6 AAAP01003822.1_7 - 0.035 13.8 1.6 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL DUF2070 PF09843.9 AAAP01003822.1_7 - 1.7 6.8 8.1 2 6.6 8.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF983 PF06170.12 AAAP01003822.1_7 - 3.3 8.2 13.3 2 8.9 5.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) CitMHS PF03600.16 AAAP01003822.1_8 - 5.6e-26 91.4 26.1 5.6e-26 91.4 26.1 2.0 1 1 1 2 2 2 1 Citrate transporter adh_short PF00106.25 AAAP01003822.1_9 - 1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003822.1_9 - 2.1e-26 93.0 0.0 2.5e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003822.1_9 - 2.2e-10 40.7 0.0 3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF86 PF01934.17 AAAP01003822.1_10 - 7e-29 100.1 0.0 8.1e-29 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 NTase_sub_bind PF08780.11 AAAP01003822.1_10 - 0.026 14.5 0.1 0.19 11.7 0.1 1.9 1 1 1 2 2 2 0 Nucleotidyltransferase substrate binding protein like NTP_transf_2 PF01909.23 AAAP01003822.1_11 - 2.5e-13 50.1 0.0 3.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AAAP01003822.1_11 - 1.3e-12 47.6 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DnaB_bind PF10410.9 AAAP01003822.1_11 - 0.066 13.4 0.7 0.12 12.6 0.7 1.3 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase DUF1732 PF08340.11 AAAP01003822.1_12 - 6.3e-34 115.8 0.6 3.3e-33 113.5 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) YicC_N PF03755.13 AAAP01003822.1_12 - 7.2e-33 114.2 0.1 7.2e-33 114.2 0.1 1.9 2 0 0 2 2 2 1 YicC-like family, N-terminal region DUF2018 PF09442.10 AAAP01003822.1_12 - 0.12 13.3 0.5 13 6.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Cluap1 PF10234.9 AAAP01003822.1_12 - 0.22 10.9 3.0 0.15 11.4 1.0 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 DinB_2 PF12867.7 AAAP01003822.1_12 - 1.2 9.7 6.6 41 4.7 6.3 2.6 1 1 0 1 1 1 0 DinB superfamily Guanylate_kin PF00625.21 AAAP01003822.1_13 - 6.5e-53 179.1 0.0 7.8e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AAAP01003822.1_13 - 1.4e-06 28.5 0.0 3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AAAP01003822.1_13 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase CPT PF07931.12 AAAP01003822.1_13 - 0.0017 18.2 0.1 0.0034 17.2 0.1 1.7 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 AAAP01003822.1_13 - 0.002 18.7 0.0 0.0053 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01003822.1_13 - 0.012 15.7 0.0 0.028 14.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AAAP01003822.1_13 - 0.074 13.3 0.0 0.22 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 AAAP01003822.1_13 - 0.15 12.6 0.0 0.26 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF1933 PF09147.10 AAAP01003822.1_14 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1933) 4HB_MCP_1 PF12729.7 AAAP01003822.1_15 - 7.3e-36 123.4 0.0 7.3e-36 123.4 0.0 3.6 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction MCPsignal PF00015.21 AAAP01003822.1_15 - 4.2e-33 114.6 44.3 5.9e-32 110.9 27.6 3.0 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 AAAP01003822.1_15 - 3.1e-22 79.4 1.1 3.1e-22 79.4 1.1 3.4 3 0 0 3 3 3 1 Tar ligand binding domain homologue DUF948 PF06103.11 AAAP01003822.1_15 - 1.2e-05 25.4 16.2 0.76 10.1 1.8 4.9 2 2 2 4 4 4 4 Bacterial protein of unknown function (DUF948) HAMP PF00672.25 AAAP01003822.1_15 - 0.00014 22.2 0.1 0.00014 22.2 0.1 4.8 4 1 1 5 5 5 1 HAMP domain DUF1664 PF07889.12 AAAP01003822.1_15 - 0.0019 18.2 10.1 0.46 10.5 0.8 3.4 2 2 0 2 2 2 2 Protein of unknown function (DUF1664) DUF3450 PF11932.8 AAAP01003822.1_15 - 0.0097 15.2 3.6 0.0097 15.2 3.6 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) IFT57 PF10498.9 AAAP01003822.1_15 - 0.027 13.5 5.8 0.99 8.3 0.3 2.6 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 AAAP01003822.1_15 - 0.039 14.0 19.1 1.3 9.0 3.7 4.6 1 1 2 4 4 4 0 Laminin Domain II UPF0242 PF06785.11 AAAP01003822.1_15 - 0.15 12.1 0.2 22 5.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_I PF06008.14 AAAP01003822.1_15 - 0.16 11.6 21.6 0.16 11.7 4.7 3.2 1 1 0 2 2 2 0 Laminin Domain I PIN_8 PF18476.1 AAAP01003822.1_15 - 0.37 10.6 13.6 0.094 12.6 0.3 3.3 2 1 2 4 4 4 0 PIN like domain Syntaxin_2 PF14523.6 AAAP01003822.1_15 - 0.73 10.2 4.1 11 6.5 1.0 3.4 2 2 1 3 3 3 0 Syntaxin-like protein Dor1 PF04124.12 AAAP01003822.1_15 - 1.2 7.7 5.3 0.97 8.1 1.3 2.2 1 1 1 2 2 2 0 Dor1-like family SKA1 PF07160.12 AAAP01003822.1_15 - 1.4 8.8 5.1 3.1 7.6 0.1 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 FliJ PF02050.16 AAAP01003822.1_15 - 1.8 8.8 14.2 0.92 9.7 2.5 2.9 2 1 0 2 2 2 0 Flagellar FliJ protein TMPIT PF07851.13 AAAP01003822.1_15 - 2.1 7.5 6.0 5.2 6.2 0.2 2.5 2 1 0 2 2 2 0 TMPIT-like protein Vps53_N PF04100.12 AAAP01003822.1_15 - 2.4 7.0 7.3 1.2 8.0 1.2 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal SNARE PF05739.19 AAAP01003822.1_15 - 7.9 6.6 6.6 8 6.5 0.1 3.4 3 1 1 4 4 4 0 SNARE domain EFG_IV PF03764.18 AAAP01003822.1_16 - 4e-42 142.8 0.0 7.4e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 AAAP01003822.1_16 - 3.5e-27 95.2 0.0 6.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AAAP01003822.1_16 - 2.3e-19 69.2 0.0 4.6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AAAP01003822.1_16 - 2.8e-15 56.1 0.0 6.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AAAP01003822.1_16 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 AAAP01003822.1_16 - 0.0037 17.1 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein SRPRB PF09439.10 AAAP01003822.1_16 - 0.0045 16.4 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 AAAP01003822.1_16 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 AAAP01003822.1_16 - 0.032 13.8 0.1 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 AAAP01003822.1_16 - 0.078 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003822.1_16 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECH_1 PF00378.20 AAAP01003822.1_17 - 3e-48 164.3 0.3 3.4e-48 164.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003822.1_17 - 2e-32 113.0 0.7 3.2e-32 112.4 0.7 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CDC37_C PF08564.10 AAAP01003822.1_17 - 0.13 12.4 0.2 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 Cdc37 C terminal domain CoA_transf_3 PF02515.17 AAAP01003822.1_18 - 1.5e-104 350.1 0.0 1.8e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III TPR_1 PF00515.28 AAAP01003822.1_19 - 2.4e-48 160.1 19.0 1.1e-07 31.3 0.1 11.2 13 0 0 13 13 12 9 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003822.1_19 - 3.6e-45 148.4 33.8 1.4e-07 31.0 0.2 12.8 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003822.1_19 - 1e-36 124.3 17.9 3.3e-07 29.9 0.0 10.0 7 3 4 11 11 11 9 TPR repeat TPR_8 PF13181.6 AAAP01003822.1_19 - 2.3e-36 120.9 5.6 4.3e-06 26.5 0.0 11.2 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003822.1_19 - 5.5e-36 122.9 60.1 4.9e-09 36.7 3.8 8.5 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003822.1_19 - 1.4e-34 118.4 36.4 1.4e-06 28.7 0.4 7.9 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003822.1_19 - 2.3e-31 105.9 10.6 3.9e-06 26.8 0.1 11.0 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003822.1_19 - 3.1e-30 102.3 54.4 0.00063 20.4 0.5 12.4 3 3 9 12 12 12 10 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003822.1_19 - 6.1e-29 100.1 43.5 7.2e-07 29.4 3.5 8.4 4 3 4 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003822.1_19 - 2.3e-28 96.1 24.4 2.3e-05 24.1 0.0 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003822.1_19 - 5.8e-20 70.5 60.9 0.00059 19.6 1.3 11.7 12 0 0 12 12 12 8 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003822.1_19 - 5e-17 61.9 1.1 6.3e-05 23.1 0.0 5.3 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 AAAP01003822.1_19 - 9.9e-12 44.3 56.2 0.083 13.6 0.2 12.8 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003822.1_19 - 1.2e-09 38.1 44.5 0.003 17.7 2.6 7.2 3 2 3 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003822.1_19 - 1.3e-09 38.1 26.3 4.1 8.3 0.0 10.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003822.1_19 - 2.5e-08 33.5 16.1 0.0098 15.1 3.4 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat NARP1 PF12569.8 AAAP01003822.1_19 - 9.6e-07 28.1 0.8 0.11 11.3 0.0 5.1 3 2 1 5 5 5 1 NMDA receptor-regulated protein 1 Glyco_transf_9 PF01075.17 AAAP01003822.1_19 - 9.7e-07 28.3 0.1 2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PPR PF01535.20 AAAP01003822.1_19 - 0.00013 22.0 6.0 1.1e+02 3.4 0.0 8.3 10 0 0 10 10 10 0 PPR repeat BTAD PF03704.17 AAAP01003822.1_19 - 0.00015 22.2 39.4 0.0052 17.2 8.8 6.2 2 2 4 6 6 6 1 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 AAAP01003822.1_19 - 0.0014 19.1 2.8 6.3 7.3 0.2 4.1 4 1 1 5 5 4 1 Alkyl sulfatase dimerisation Coatomer_E PF04733.14 AAAP01003822.1_19 - 0.0061 16.0 0.6 3.3 7.0 0.0 3.3 2 2 2 4 4 4 1 Coatomer epsilon subunit TPR_20 PF14561.6 AAAP01003822.1_19 - 0.073 13.4 19.8 2.3 8.6 0.1 6.9 3 3 2 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 AAAP01003822.1_19 - 0.11 12.6 9.8 11 6.1 0.5 7.1 4 2 2 7 7 7 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 AAAP01003822.1_19 - 0.18 11.8 6.4 9.4 6.3 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AAAP01003822.1_19 - 0.22 11.4 9.5 6.1 6.7 0.1 3.8 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal dCache_1 PF02743.18 AAAP01003822.1_20 - 1e-15 58.2 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Cache domain dCache_2 PF08269.11 AAAP01003822.1_20 - 0.064 12.4 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Cache domain ClpB_D2-small PF10431.9 AAAP01003823.1_1 - 5.1e-27 93.8 0.0 6.4e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.14 AAAP01003823.1_1 - 0.23 11.6 0.1 0.31 11.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NifW PF03206.14 AAAP01003823.1_2 - 2.8e-27 95.1 0.0 3.1e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Nitrogen fixation protein NifW HMGL-like PF00682.19 AAAP01003823.1_3 - 1.4e-81 273.9 1.8 2e-81 273.5 1.8 1.1 1 0 0 1 1 1 1 HMGL-like Ribosomal_S11 PF00411.19 AAAP01003823.1_3 - 0.085 13.3 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S11 Fe-S_biosyn PF01521.20 AAAP01003823.1_4 - 9.6e-15 54.7 0.1 1.8e-14 53.8 0.0 1.5 1 1 1 2 2 2 1 Iron-sulphur cluster biosynthesis NifQ PF04891.12 AAAP01003823.1_5 - 3.1e-58 196.7 0.0 3.6e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 NifQ Fer4_6 PF12837.7 AAAP01003823.1_6 - 5.4e-11 42.1 10.4 2.9e-05 24.0 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003823.1_6 - 7.2e-11 42.1 15.3 1.2e-08 34.9 7.0 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003823.1_6 - 4.7e-10 38.9 16.1 1.2e-05 24.9 1.6 2.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003823.1_6 - 3.2e-09 37.2 7.2 8.3e-09 35.9 7.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003823.1_6 - 1.2e-08 35.8 4.8 1.8e-08 35.2 4.8 1.3 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003823.1_6 - 6.2e-08 32.6 9.7 4.5e-07 29.9 9.7 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003823.1_6 - 8.3e-08 32.2 9.1 3.9e-07 30.1 9.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003823.1_6 - 1.3e-06 29.2 7.7 0.00037 21.3 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003823.1_6 - 1.4e-06 28.0 11.6 0.0016 18.4 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003823.1_6 - 2.4e-06 28.0 2.8 0.0091 16.5 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003823.1_6 - 2.1e-05 24.9 9.6 0.00028 21.2 10.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003823.1_6 - 8.7e-05 22.7 12.1 0.044 14.3 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003823.1_6 - 0.00012 22.8 17.5 0.052 14.5 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003823.1_6 - 0.0028 17.9 8.6 0.033 14.4 1.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003823.1_6 - 0.26 11.9 11.5 2 9.0 2.6 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAAP01003823.1_6 - 0.59 10.9 14.0 1.1 10.1 2.8 2.3 1 1 1 2 2 2 0 4Fe-4S single cluster domain zf-C2H2_11 PF16622.5 AAAP01003823.1_6 - 0.96 9.3 11.0 2.3 8.1 0.7 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF269 PF03270.13 AAAP01003823.1_7 - 2.1e-49 166.6 0.0 2.5e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF269 Nitro_FeMo-Co PF02579.17 AAAP01003823.1_8 - 4.4e-20 71.8 0.1 5.5e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Oxidored_nitro PF00148.19 AAAP01003823.1_9 - 1.9e-109 366.1 0.6 2.1e-109 365.9 0.6 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DHO_dh PF01180.21 AAAP01003823.1_9 - 0.047 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Oxidored_nitro PF00148.19 AAAP01003823.1_10 - 9.1e-103 344.1 0.0 1e-102 343.9 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Med22 PF06179.12 AAAP01003823.1_10 - 0.089 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex Acetyltransf_1 PF00583.25 AAAP01003823.1_11 - 4.8e-16 59.1 0.1 6.2e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003823.1_11 - 2.1e-09 37.7 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003823.1_11 - 9.9e-09 35.2 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003823.1_11 - 9.6e-05 22.3 0.0 0.00033 20.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 AAAP01003823.1_11 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01003823.1_11 - 0.00081 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 AAAP01003823.1_11 - 0.0046 17.1 0.0 0.0049 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Oxidored_nitro PF00148.19 AAAP01003823.1_12 - 9.3e-120 400.0 0.0 1.1e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF3364 PF11844.8 AAAP01003823.1_12 - 5.4e-24 84.2 2.9 1.1e-23 83.2 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3364) Flagellin_IN PF07196.13 AAAP01003823.1_12 - 0.072 13.3 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif Oxidored_nitro PF00148.19 AAAP01003823.1_13 - 5.2e-113 377.8 0.0 6.2e-113 377.5 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Fer4_NifH PF00142.18 AAAP01003823.1_14 - 7.2e-99 330.6 0.8 8.2e-99 330.4 0.8 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DNA_ligase_A_N PF04675.14 AAAP01003823.1_14 - 0.076 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA ligase N terminus DUF1896 PF08989.10 AAAP01003823.1_14 - 0.084 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) Fer4_NifH PF00142.18 AAAP01003823.1_15 - 5.2e-28 98.3 0.0 6e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 AAAP01003823.1_15 - 2.3e-09 37.4 0.0 2.3e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 AAAP01003823.1_15 - 2.5e-08 33.4 0.0 2.8e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 AAAP01003823.1_15 - 2.5e-07 30.8 0.2 3.1e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAAP01003823.1_15 - 3.5e-05 23.4 0.0 3.6e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MeaB PF03308.16 AAAP01003823.1_15 - 0.00086 18.4 0.0 0.00094 18.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MipZ PF09140.11 AAAP01003823.1_15 - 0.00099 18.5 0.0 0.001 18.4 0.0 1.0 1 0 0 1 1 1 1 ATPase MipZ AAA_24 PF13479.6 AAAP01003823.1_15 - 0.0031 17.3 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 AAAP01003823.1_15 - 0.013 14.4 0.0 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 AAAP01003823.1_15 - 0.016 14.8 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 AAAP01003823.1_15 - 0.036 13.8 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 AAAP01003823.1_15 - 0.089 12.8 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AAAP01003823.1_15 - 0.11 11.6 0.2 0.14 11.3 0.2 1.1 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 AAAP01003823.1_15 - 0.12 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 AAAP01003823.1_15 - 0.13 12.7 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 AAAP01003823.1_15 - 0.13 11.7 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DRAT PF07357.11 AAAP01003823.1_16 - 1.2e-113 378.6 0.0 1.3e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) ADP_ribosyl_GH PF03747.14 AAAP01003823.1_17 - 5.4e-59 200.3 5.6 4.7e-58 197.2 5.6 1.9 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase ArsC PF03960.15 AAAP01003823.1_18 - 0.00016 21.6 0.0 0.00066 19.6 0.0 1.8 2 0 0 2 2 2 1 ArsC family MCPsignal PF00015.21 AAAP01003823.1_19 - 4.7e-32 111.2 51.9 1.3e-31 109.7 27.1 4.0 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003823.1_19 - 1.1e-10 41.8 1.0 1.1e-09 38.5 0.0 3.5 3 0 0 3 3 2 1 HAMP domain DUF3450 PF11932.8 AAAP01003823.1_19 - 0.0071 15.7 13.7 0.23 10.7 3.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) HTH_Tnp_ISL3 PF13542.6 AAAP01003823.1_19 - 0.056 12.9 2.6 0.17 11.3 1.3 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF1664 PF07889.12 AAAP01003823.1_19 - 0.094 12.8 17.7 1.2 9.2 1.2 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 AAAP01003823.1_19 - 0.62 9.9 5.1 1.1 9.0 0.6 2.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 AAAP01003823.1_19 - 0.71 10.2 40.5 0.045 14.0 1.4 7.4 4 2 2 7 7 7 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 AAAP01003823.1_19 - 0.76 9.0 3.1 6.3 5.9 0.3 2.6 2 0 0 2 2 2 0 TMPIT-like protein FtsX PF02687.21 AAAP01003823.1_19 - 0.88 10.1 4.8 1.8 9.1 0.3 2.3 2 0 0 2 2 2 0 FtsX-like permease family Syntaxin_2 PF14523.6 AAAP01003823.1_19 - 1 9.7 12.5 15 6.0 0.0 5.0 4 2 1 5 5 5 0 Syntaxin-like protein Vps53_N PF04100.12 AAAP01003823.1_19 - 2.4 7.0 14.4 0.65 8.9 2.5 2.5 1 1 0 2 2 2 0 Vps53-like, N-terminal Sec34 PF04136.15 AAAP01003823.1_19 - 5.3 6.9 8.8 28 4.5 0.4 4.1 3 3 2 5 5 5 0 Sec34-like family Mer2 PF09074.10 AAAP01003823.1_19 - 7 6.4 10.0 3.8 7.3 1.4 3.3 2 1 1 3 3 3 0 Mer2 BLOC1_2 PF10046.9 AAAP01003823.1_19 - 8 6.8 12.5 21 5.5 0.3 5.0 4 2 1 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fer2 PF00111.27 AAAP01003823.1_20 - 1.3e-11 44.3 1.1 3.4e-11 42.9 1.1 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SIR2_2 PF13289.6 AAAP01003823.1_21 - 2.6e-25 89.2 0.0 3.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 SIR2-like domain NHL PF01436.21 AAAP01003823.1_21 - 0.048 13.7 0.1 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 NHL repeat NifT PF06988.11 AAAP01003823.1_22 - 8.4e-28 96.0 0.6 9.5e-28 95.8 0.6 1.0 1 0 0 1 1 1 1 NifT/FixU protein NifZ PF04319.13 AAAP01003823.1_23 - 3e-29 100.6 0.1 5.7e-29 99.7 0.0 1.5 2 0 0 2 2 2 1 NifZ domain Fer4 PF00037.27 AAAP01003823.1_24 - 2.3e-06 27.2 2.7 2.3e-06 27.2 2.7 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003823.1_24 - 4.1e-06 27.3 13.5 8.1e-06 26.3 13.5 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003823.1_24 - 1e-05 25.5 14.4 1.5e-05 25.0 14.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003823.1_24 - 3.7e-05 23.7 15.1 4.6e-05 23.5 14.6 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003823.1_24 - 0.00017 21.7 14.8 0.00027 21.1 14.8 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003823.1_24 - 0.00018 21.4 12.8 0.02 14.9 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003823.1_24 - 0.00093 20.1 15.9 0.022 15.7 8.7 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AAAP01003823.1_24 - 0.0025 18.2 14.8 0.017 15.6 3.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003823.1_24 - 0.0072 16.8 14.7 0.0086 16.6 4.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003823.1_24 - 0.0098 15.9 2.7 0.0098 15.9 2.7 2.4 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003823.1_24 - 0.013 16.0 14.3 0.16 12.5 1.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003823.1_24 - 0.47 11.5 20.7 1.8 9.7 4.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Radical_SAM PF04055.21 AAAP01003823.1_25 - 2.8e-25 89.6 0.0 5.3e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Nitro_FeMo-Co PF02579.17 AAAP01003823.1_25 - 3.8e-21 75.2 0.1 3.8e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor GatB_N PF02934.15 AAAP01003823.1_26 - 1e-109 366.2 0.0 1.4e-109 365.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AAAP01003823.1_26 - 4.4e-49 166.2 0.3 6.9e-49 165.5 0.3 1.2 1 0 0 1 1 1 1 GatB domain Amidase PF01425.21 AAAP01003823.1_27 - 4.1e-148 494.1 0.1 4.8e-148 493.9 0.1 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 AAAP01003823.1_28 - 7.2e-22 77.4 0.0 8.9e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit PAS PF00989.25 AAAP01003823.1_29 - 0.00078 19.4 0.0 0.00093 19.2 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003823.1_29 - 0.0047 17.2 0.0 0.0052 17.0 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_10 PF13596.6 AAAP01003823.1_29 - 0.0094 16.5 0.0 0.0097 16.5 0.0 1.0 1 0 0 1 1 1 1 PAS domain MLTR_LBD PF17765.1 AAAP01003823.1_29 - 0.018 15.2 0.1 0.025 14.7 0.1 1.4 1 1 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Asparaginase_C PF17763.1 AAAP01003823.1_29 - 0.074 13.3 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain PAS_8 PF13188.7 AAAP01003823.1_29 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 PAS domain DAO PF01266.24 AAAP01003823.1_29 - 0.11 12.0 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phage_holin_3_6 PF07332.11 AAAP01003824.1_1 - 0.015 15.3 3.6 0.018 15.1 3.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Bax1-I PF01027.20 AAAP01003824.1_1 - 0.032 14.0 1.4 0.036 13.9 1.4 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.6 AAAP01003824.1_1 - 0.095 12.3 1.7 0.099 12.3 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2892 PF11127.8 AAAP01003824.1_1 - 0.18 11.9 8.0 0.29 11.2 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) PEP-CTERM PF07589.11 AAAP01003824.1_1 - 1.3 9.2 7.5 3.2 8.0 2.0 2.3 2 0 0 2 2 2 0 PEP-CTERM motif FixS PF03597.15 AAAP01003824.1_1 - 3.1 7.6 10.7 1.8 8.3 4.4 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type MCR PF18509.1 AAAP01003824.1_2 - 2.6e-30 103.7 13.0 5.5e-15 54.6 4.5 2.6 2 0 0 2 2 2 2 Magnetochrome domain Trypsin_2 PF13365.6 AAAP01003824.1_2 - 2.2e-28 100.1 2.3 2.2e-28 100.1 2.3 2.1 2 0 0 2 2 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAAP01003824.1_2 - 1.9e-24 85.8 1.6 4.3e-13 49.4 0.0 3.6 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 AAAP01003824.1_2 - 5.4e-24 83.8 9.4 9.5e-14 51.0 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AAAP01003824.1_2 - 4e-19 68.8 0.2 2e-08 34.5 0.0 3.1 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AAAP01003824.1_2 - 1.1e-14 54.8 0.1 1.7e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AAAP01003824.1_2 - 3.2e-05 23.8 0.2 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 Tricorn protease PDZ domain Cytochrom_C PF00034.21 AAAP01003824.1_2 - 0.00047 21.3 0.4 0.036 15.2 0.1 2.5 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003824.1_2 - 0.0032 17.8 0.8 1.1 9.7 0.3 2.7 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Peptidase_S55 PF05580.12 AAAP01003824.1_2 - 0.0039 17.2 1.2 0.0058 16.6 0.4 1.6 2 0 0 2 2 2 1 SpoIVB peptidase S55 Peptidase_S29 PF02907.15 AAAP01003824.1_2 - 0.0073 16.1 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 AAAP01003824.1_2 - 0.015 14.0 0.7 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 CCP_MauG PF03150.14 AAAP01003824.1_2 - 0.096 13.3 0.0 6.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase PSCyt3 PF07627.11 AAAP01003824.1_2 - 0.13 12.5 0.1 27 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Cytochrom_c3_2 PF14537.6 AAAP01003824.1_2 - 0.25 11.8 2.3 1 9.9 2.3 1.8 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 AAAP01003824.1_2 - 0.6 10.1 3.3 6 6.9 3.7 2.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003824.1_2 - 1.5 8.6 4.1 21 4.9 4.1 2.2 1 1 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) MreB_Mbl PF06723.13 AAAP01003824.1_4 - 2.7e-22 79.0 0.0 3.4e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 AAAP01003824.1_4 - 3.2e-10 39.2 0.0 7.8e-07 28.0 0.0 2.1 1 1 0 2 2 2 2 Actin FtsA PF14450.6 AAAP01003824.1_4 - 0.00013 22.3 0.1 0.0035 17.7 0.0 2.3 2 0 0 2 2 2 1 Cell division protein FtsA DDR PF08841.10 AAAP01003824.1_4 - 0.028 13.4 0.0 0.63 9.0 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 AAAP01003824.1_4 - 0.037 12.2 0.5 0.63 8.2 0.2 2.3 2 1 0 2 2 2 0 Hsp70 protein ALP_N PF17989.1 AAAP01003824.1_4 - 0.14 12.4 0.0 0.4 10.8 0.0 1.9 1 1 0 1 1 1 0 Actin like proteins N terminal domain LapA_dom PF06305.11 AAAP01003824.1_5 - 0.016 15.0 0.2 0.016 15.0 0.2 2.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Cation_efflux PF01545.21 AAAP01003824.1_6 - 9e-42 143.1 11.6 1.1e-41 142.8 11.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003824.1_6 - 1.1e-15 57.5 0.6 1.9e-15 56.8 0.6 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter CitMHS PF03600.16 AAAP01003824.1_7 - 4.8e-26 91.7 41.1 1.1e-25 90.4 41.1 1.6 1 1 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 AAAP01003824.1_7 - 4.3e-06 26.0 27.8 0.00011 21.4 15.1 2.2 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region TauE PF01925.19 AAAP01003824.1_8 - 1.6e-35 122.8 30.6 1.6e-35 122.8 30.6 1.9 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE Trypsin_2 PF13365.6 AAAP01003824.1_8 - 4.4e-16 60.1 0.9 1e-15 59.0 0.9 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AAAP01003824.1_8 - 0.12 12.2 0.6 1.7 8.4 0.6 2.2 1 1 0 1 1 1 0 Trypsin MCR PF18509.1 AAAP01003824.1_9 - 8.9e-15 54.0 5.1 3.9e-10 39.1 0.8 2.5 2 0 0 2 2 2 2 Magnetochrome domain PDZ_2 PF13180.6 AAAP01003824.1_9 - 1.4e-05 25.3 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AAAP01003824.1_9 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_1 PF12812.7 AAAP01003824.1_9 - 0.01 15.8 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 PDZ-like domain TPR_2 PF07719.17 AAAP01003824.1_10 - 1.2e-19 68.8 0.1 4.2e-05 23.3 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003824.1_10 - 6e-19 68.4 0.9 7.8e-08 32.9 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003824.1_10 - 7.7e-19 66.7 0.1 3.4e-06 26.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003824.1_10 - 9.6e-18 64.5 0.5 1.4e-07 31.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003824.1_10 - 5.1e-16 57.5 0.0 0.00052 20.0 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003824.1_10 - 7.9e-15 54.3 1.0 0.004 17.9 0.0 5.2 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003824.1_10 - 1.6e-14 54.0 0.2 1.6e-05 25.1 0.0 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003824.1_10 - 6.7e-13 47.7 0.1 0.0036 17.2 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003824.1_10 - 2.5e-11 43.0 0.0 0.0071 16.0 0.0 4.5 2 1 2 4 4 4 4 TPR repeat TPR_17 PF13431.6 AAAP01003824.1_10 - 3.5e-10 39.5 0.0 0.0011 19.1 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003824.1_10 - 4.5e-10 39.1 1.6 2.2 8.3 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003824.1_10 - 2.7e-09 37.0 0.0 0.52 11.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003824.1_10 - 3.7e-09 36.7 0.0 0.0001 22.5 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 AAAP01003824.1_10 - 9.5e-07 29.0 0.6 0.036 14.1 0.0 3.1 2 1 1 3 3 3 3 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 AAAP01003824.1_10 - 1.3e-06 28.4 0.6 1.7 8.9 0.1 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003824.1_10 - 6.9e-06 26.3 0.0 0.05 13.9 0.0 3.9 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003824.1_10 - 0.00021 21.6 0.2 7.6 7.5 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003824.1_10 - 0.00045 19.5 0.0 0.077 12.2 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 AAAP01003824.1_10 - 0.0082 16.2 0.0 1.9 8.6 0.0 3.3 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 AAAP01003824.1_10 - 0.021 15.3 0.0 0.08 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain PPR PF01535.20 AAAP01003824.1_10 - 0.048 13.9 0.0 65 4.1 0.0 4.1 4 0 0 4 4 4 0 PPR repeat LemA PF04011.12 AAAP01003824.1_11 - 9.9e-25 87.1 0.0 3.1e-24 85.5 0.0 1.8 1 1 0 1 1 1 1 LemA family HTH_17 PF12728.7 AAAP01003824.1_12 - 3.6e-07 30.2 0.0 6.6e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain UPF0175 PF03683.13 AAAP01003824.1_12 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) Cation_efflux PF01545.21 AAAP01003824.1_13 - 1.1e-41 142.8 11.5 1.3e-41 142.5 11.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003824.1_13 - 8.6e-10 38.6 0.1 1.3e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Acyl_CoA_thio PF02551.15 AAAP01003824.1_13 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA thioesterase MCR PF18509.1 AAAP01003824.1_15 - 1.2e-16 60.0 16.2 1.4e-09 37.3 4.3 2.3 2 0 0 2 2 2 2 Magnetochrome domain Paired_CXXCH_1 PF09699.10 AAAP01003824.1_15 - 0.013 15.2 1.4 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DAGK_cat PF00781.24 AAAP01003824.1_16 - 1.2e-14 54.0 0.0 1.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cation_efflux PF01545.21 AAAP01003824.1_17 - 8.5e-38 130.1 14.9 1e-37 129.8 14.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003824.1_17 - 2.2e-10 40.5 0.4 3.7e-10 39.8 0.4 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF150 PF02576.17 AAAP01003824.1_17 - 0.019 15.4 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 RimP N-terminal domain Phage_holin_2_4 PF16082.5 AAAP01003824.1_17 - 0.43 10.4 7.0 0.23 11.2 3.9 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Response_reg PF00072.24 AAAP01003824.1_18 - 0.01 16.0 0.0 0.011 15.8 0.0 1.0 1 0 0 1 1 1 0 Response regulator receiver domain Response_reg PF00072.24 AAAP01003824.1_20 - 5.6e-05 23.3 0.0 8.8e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Response regulator receiver domain HTH_19 PF12844.7 AAAP01003824.1_23 - 3.6e-07 30.1 0.1 5.5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003824.1_23 - 1.7e-05 24.8 0.1 2.8e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 AAAP01003824.1_23 - 0.00015 21.5 0.4 0.0026 17.6 0.4 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAAP01003824.1_23 - 0.00022 21.5 0.3 0.00042 20.6 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003824.1_23 - 0.0043 17.4 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Herpes_UL4 PF03277.13 AAAP01003824.1_23 - 0.25 11.0 0.7 0.38 10.4 0.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL4 family Phage_integrase PF00589.22 AAAP01003825.1_4 - 2.7e-24 85.9 0.2 3e-24 85.7 0.2 1.0 1 0 0 1 1 1 1 Phage integrase family FliMN_C PF01052.20 AAAP01003825.1_4 - 0.0034 17.4 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term Phage_integr_3 PF16795.5 AAAP01003825.1_4 - 0.026 14.5 0.1 0.21 11.5 0.1 2.1 1 1 0 1 1 1 0 Archaeal phage integrase zf-CpG_bind_C PF12269.8 AAAP01003825.1_5 - 0.055 13.2 1.7 0.054 13.3 1.7 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF2500 PF10694.9 AAAP01003825.1_5 - 0.15 12.5 1.1 0.16 12.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Hemerythrin PF01814.23 AAAP01003825.1_6 - 1.1e-06 29.2 6.8 1.5e-06 28.8 6.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AAA_21 PF13304.6 AAAP01003825.1_7 - 3.9e-10 40.0 0.2 3.6e-06 27.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003825.1_7 - 2.8e-08 34.5 0.1 3.5e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01003825.1_7 - 1.8e-06 27.9 0.3 0.00012 22.0 0.4 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AAAP01003825.1_7 - 1.5e-05 24.6 0.1 8.4e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003825.1_7 - 4.8e-05 23.0 0.2 8.1e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAAP01003825.1_7 - 9.2e-05 23.0 0.1 0.00094 19.7 0.1 2.1 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 AAAP01003825.1_7 - 0.01 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAAP01003825.1_7 - 0.032 14.5 0.2 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003825.1_7 - 0.035 14.0 0.1 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AAAP01003825.1_7 - 0.088 13.2 0.3 0.12 12.7 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AAAP01003825.1_7 - 0.097 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01003825.1_7 - 0.15 11.7 0.1 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAAP01003825.1_7 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01003825.1_7 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 AAAP01003825.1_9 - 1.4e-31 109.8 0.0 1.9e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAAP01003825.1_9 - 6.2e-09 36.3 0.0 1.4e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 AAAP01003825.1_9 - 3.2e-07 30.9 0.0 5.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AAAP01003825.1_9 - 8.5e-07 29.1 0.0 0.0009 19.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AAAP01003825.1_9 - 9.3e-05 22.7 0.0 0.00072 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003825.1_9 - 0.00017 21.2 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 AAAP01003825.1_9 - 0.00051 20.0 0.0 0.055 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SMC_N PF02463.19 AAAP01003825.1_9 - 0.0023 17.4 0.0 0.0089 15.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01003825.1_9 - 0.0044 17.0 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 AAAP01003825.1_9 - 0.01 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 AAAP01003825.1_9 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 AAAP01003825.1_9 - 0.026 14.6 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 AAAP01003825.1_9 - 0.05 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 AAAP01003825.1_9 - 0.052 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 AAAP01003825.1_9 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 AAAP01003825.1_9 - 0.08 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01003825.1_9 - 0.09 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 AAAP01003825.1_9 - 0.099 12.2 0.0 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 AAAP01003825.1_9 - 0.099 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3265 PF11665.8 AAAP01003825.1_9 - 0.11 12.8 0.2 0.31 11.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) Sigma54_activat PF00158.26 AAAP01003825.1_9 - 0.17 11.6 0.0 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 AAAP01003825.1_9 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2813 PF11398.8 AAAP01003825.1_9 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) ABC_tran PF00005.27 AAAP01003825.1_10 - 5.4e-24 85.3 0.0 7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AAAP01003825.1_10 - 6.6e-15 55.4 0.6 1.2e-14 54.6 0.6 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AAAP01003825.1_10 - 4.6e-06 26.7 0.1 0.00011 22.2 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003825.1_10 - 0.002 17.6 0.0 0.0051 16.3 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain KDGP_aldolase PF07071.11 AAAP01003825.1_10 - 0.042 13.6 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 KDGP aldolase ATP-synt_ab PF00006.25 AAAP01003825.1_10 - 0.051 13.2 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ytp1 PF10355.9 AAAP01003825.1_10 - 0.076 12.2 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) AAA_29 PF13555.6 AAAP01003825.1_10 - 0.16 11.8 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain BPD_transp_1 PF00528.22 AAAP01003825.1_11 - 9.7e-31 106.9 8.5 9.7e-31 106.9 8.5 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAAP01003825.1_11 - 3.7e-05 23.6 0.7 3.7e-05 23.6 0.7 2.3 2 1 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AAAP01003825.1_12 - 6.8e-39 133.5 19.5 6.8e-39 133.5 19.5 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AAAP01003825.1_13 - 1.6e-80 270.9 4.6 1.9e-80 270.6 4.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Amidase PF01425.21 AAAP01003825.1_14 - 4.7e-89 299.4 1.2 6.6e-89 298.9 1.2 1.2 1 0 0 1 1 1 1 Amidase FCD PF07729.12 AAAP01003825.1_15 - 2.1e-24 86.4 7.4 3.2e-24 85.7 7.4 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01003825.1_15 - 2.2e-19 68.8 0.8 4.5e-19 67.9 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AAAP01003825.1_15 - 0.0003 20.7 0.4 0.0018 18.2 0.5 2.1 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAAP01003825.1_15 - 0.0034 17.2 0.3 0.012 15.5 0.1 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AAAP01003825.1_15 - 0.0041 17.0 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAAP01003825.1_15 - 0.01 15.4 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_CodY PF08222.11 AAAP01003825.1_15 - 0.02 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_11 PF08279.12 AAAP01003825.1_15 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 AAAP01003825.1_15 - 0.029 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AAAP01003825.1_15 - 0.039 13.7 0.2 0.096 12.5 0.2 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4423 PF14394.6 AAAP01003825.1_15 - 0.11 12.1 0.0 0.41 10.3 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4423) HTH_36 PF13730.6 AAAP01003825.1_15 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MCPsignal PF00015.21 AAAP01003825.1_16 - 1.4e-29 103.1 57.3 1.5e-29 103.0 29.8 4.7 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003825.1_16 - 1.3e-10 41.5 0.1 1.3e-10 41.5 0.1 4.1 4 0 0 4 4 4 1 HAMP domain PilZ PF07238.14 AAAP01003825.1_16 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 PilZ domain DUF1664 PF07889.12 AAAP01003825.1_16 - 0.036 14.1 21.2 0.53 10.3 0.6 5.5 3 3 2 5 5 5 0 Protein of unknown function (DUF1664) DASH_Dad4 PF08650.10 AAAP01003825.1_16 - 0.12 12.4 0.6 5.4 7.1 0.0 3.7 3 1 1 4 4 4 0 DASH complex subunit Dad4 DUF948 PF06103.11 AAAP01003825.1_16 - 0.54 10.5 25.6 3 8.2 0.3 6.1 3 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) HTH_15 PF12324.8 AAAP01003825.1_16 - 7.5 6.6 7.4 3.7 7.6 0.2 3.7 2 1 1 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase STAS_2 PF13466.6 AAAP01003825.1_17 - 1.1e-12 48.1 1.7 1.3e-12 47.8 1.7 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003825.1_17 - 9.6e-09 34.9 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 STAS domain SpoIIE PF07228.12 AAAP01003825.1_18 - 9.4e-29 100.7 0.0 1.6e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAAP01003825.1_18 - 3.8e-24 85.0 0.0 5.8e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAAP01003825.1_18 - 4.9e-12 45.9 0.0 1.9e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain KorB_C PF06613.11 AAAP01003825.1_18 - 0.29 11.2 1.2 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Response_reg PF00072.24 AAAP01003825.1_19 - 4.2e-42 142.8 0.1 1.7e-27 95.8 0.2 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003825.1_19 - 6.8e-27 94.2 0.1 3e-26 92.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 AAAP01003825.1_19 - 2.9e-12 46.7 2.1 2.9e-12 46.7 2.1 1.8 2 0 0 2 2 2 1 Hpt domain HATPase_c_3 PF13589.6 AAAP01003825.1_19 - 0.17 11.7 0.2 0.31 10.8 0.2 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EAL PF00563.20 AAAP01003826.1_1 - 3e-34 118.6 0.0 3.5e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 EAL domain MFS_1 PF07690.16 AAAP01003826.1_2 - 2.5e-29 102.3 47.4 7.6e-19 67.8 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3584 PF12128.8 AAAP01003826.1_3 - 0.0052 14.4 3.3 0.0064 14.1 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Phasin PF05597.11 AAAP01003826.1_3 - 0.0059 16.6 2.5 0.0086 16.1 2.0 1.5 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) APP_E2 PF12925.7 AAAP01003826.1_3 - 0.015 15.0 3.0 0.02 14.6 3.0 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein 7TMR-HDED PF07697.11 AAAP01003826.1_3 - 0.06 13.5 1.0 0.083 13.0 1.0 1.2 1 0 0 1 1 1 0 7TM-HD extracellular CDC37_N PF03234.14 AAAP01003826.1_3 - 0.063 14.2 2.9 9.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF948 PF06103.11 AAAP01003826.1_3 - 0.063 13.5 1.3 0.33 11.2 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LapA_dom PF06305.11 AAAP01003826.1_3 - 0.07 12.9 0.3 0.17 11.7 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Bacillus_HBL PF05791.11 AAAP01003826.1_3 - 0.13 12.1 2.9 2 8.2 2.9 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3496 PF12001.8 AAAP01003826.1_3 - 0.21 12.0 3.3 0.21 12.0 1.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) PspB PF06667.12 AAAP01003826.1_3 - 0.21 11.6 3.0 12 6.0 3.0 2.3 1 1 0 1 1 1 0 Phage shock protein B LUC7 PF03194.15 AAAP01003826.1_3 - 0.24 11.1 4.2 0.28 10.8 4.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus AF0941-like PF14591.6 AAAP01003826.1_3 - 0.63 10.6 5.5 0.32 11.6 1.5 2.0 1 1 1 2 2 2 0 AF0941-like Fib_alpha PF08702.10 AAAP01003826.1_3 - 0.96 9.6 3.5 2 8.6 2.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RHH_1 PF01402.21 AAAP01003826.1_3 - 1 9.4 5.0 4.6 7.3 0.3 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Adhesin_P1_N PF18652.1 AAAP01003826.1_3 - 2.4 8.2 8.9 0.29 11.2 0.7 2.3 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Metal_resist PF13801.6 AAAP01003826.1_3 - 2.9 8.1 13.2 1.3 9.2 9.8 2.1 1 1 0 2 2 2 0 Heavy-metal resistance CAP_N PF01213.19 AAAP01003826.1_3 - 8.8 5.7 12.8 5.4 6.4 0.5 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Lysine_decarbox PF03641.14 AAAP01003826.1_4 - 2.6e-32 111.7 0.0 4.4e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AAAP01003826.1_4 - 1.5e-08 34.4 0.0 4e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 SLOG cluster4 family Lactamase_B PF00753.27 AAAP01003826.1_5 - 9.7e-25 87.7 1.5 1.2e-24 87.4 1.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AAAP01003826.1_5 - 0.0089 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF5612 PF18462.1 AAAP01003826.1_6 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) DNA_methylase PF00145.17 AAAP01003826.1_7 - 1.4e-33 116.7 0.0 2.7e-27 96.0 0.0 2.0 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Vsr PF03852.15 AAAP01003826.1_8 - 1.3e-29 101.8 0.2 2.3e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 DNA mismatch endonuclease Vsr DUF5338 PF17273.2 AAAP01003826.1_8 - 0.073 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) AIPR PF10592.9 AAAP01003826.1_9 - 2.5e-78 263.7 0.0 3.2e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 AIPR protein DUF4420 PF14390.6 AAAP01003826.1_10 - 5.9e-63 212.9 0.0 6.7e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Putative PD-(D/E)XK family member, (DUF4420) Z1 PF10593.9 AAAP01003826.1_11 - 1.1e-83 280.3 0.0 1.6e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 Z1 domain HATPase_c_3 PF13589.6 AAAP01003826.1_12 - 5.4e-26 91.0 0.0 9.3e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01003826.1_12 - 0.042 14.4 0.0 0.085 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma70_r4 PF04545.16 AAAP01003826.1_13 - 7.7e-20 70.2 6.9 3.7e-19 68.0 1.2 3.0 2 1 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAAP01003826.1_13 - 3.3e-12 46.0 0.2 8.7e-12 44.6 0.2 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Ank_2 PF12796.7 AAAP01003826.1_13 - 4.9e-10 39.9 0.2 9.8e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Sigma70_r3 PF04539.16 AAAP01003826.1_13 - 4e-09 36.4 8.1 1.8e-08 34.4 0.5 3.7 3 0 0 3 3 3 1 Sigma-70 region 3 Ank_4 PF13637.6 AAAP01003826.1_13 - 1.5e-08 35.0 0.3 0.00015 22.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 AAAP01003826.1_13 - 1.9e-06 28.0 0.8 7.9e-06 26.1 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 AAAP01003826.1_13 - 2.4e-06 27.7 0.1 5.8e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 AAAP01003826.1_13 - 0.00021 21.5 0.2 0.00074 19.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Sigma70_ner PF04546.13 AAAP01003826.1_13 - 0.058 13.3 0.8 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Sigma70_r4_2 PF08281.12 AAAP01003826.1_13 - 0.52 10.0 2.8 2.3 8.0 0.3 3.0 2 1 0 2 2 2 0 Sigma-70, region 4 WYL PF13280.6 AAAP01003826.1_14 - 7.8e-09 35.8 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 WYL domain Baculo_gp41 PF04700.12 AAAP01003826.1_15 - 0.038 13.8 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region SoPB_HTH PF18090.1 AAAP01003826.1_15 - 0.042 14.0 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Centromere-binding protein HTH domain Resolvase PF00239.21 AAAP01003826.1_16 - 6.4e-38 130.1 0.0 1.1e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 AAAP01003826.1_16 - 3.1e-15 56.4 1.2 6e-15 55.5 1.2 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 AAAP01003826.1_16 - 1.1e-09 38.7 0.0 2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Recombinase Ogr_Delta PF04606.12 AAAP01003826.1_16 - 0.28 11.2 2.5 0.57 10.2 2.5 1.6 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DUF2924 PF11149.8 AAAP01003826.1_17 - 1.1e-50 171.5 0.0 1.3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2924) HTH_31 PF13560.6 AAAP01003826.1_19 - 1.7e-10 41.0 6.8 3.9e-10 39.9 3.8 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003826.1_19 - 5.7e-09 35.9 1.5 1e-08 35.1 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003826.1_19 - 5.8e-09 35.8 2.3 3.2e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AAAP01003826.1_19 - 0.0025 17.6 2.9 0.0063 16.3 0.5 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 AAAP01003826.1_19 - 0.012 15.6 0.0 0.73 9.8 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain T3SS_ATPase_C PF18269.1 AAAP01003826.1_19 - 0.045 13.6 0.0 0.083 12.8 0.0 1.6 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Peptidase_M78 PF06114.13 AAAP01003826.1_20 - 0.0076 16.2 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 IrrE N-terminal-like domain ABC_tran PF00005.27 AAAP01003827.1_1 - 6.1e-17 62.4 0.0 7.2e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01003827.1_1 - 8.2e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003827.1_1 - 0.00047 20.7 0.0 0.00047 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003827.1_1 - 0.0014 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 AAAP01003827.1_1 - 0.0016 18.1 0.1 0.0058 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AAAP01003827.1_1 - 0.012 15.3 0.2 0.039 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAAP01003827.1_1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 AAAP01003827.1_1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_21 PF13304.6 AAAP01003827.1_1 - 0.025 14.4 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 AAAP01003827.1_1 - 0.049 13.3 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 AAAP01003827.1_1 - 0.078 12.4 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 AAAP01003827.1_1 - 0.096 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MukB PF04310.12 AAAP01003827.1_1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal GATase_2 PF00310.21 AAAP01003827.1_2 - 2.6e-185 616.1 0.0 3.1e-185 615.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 AAAP01003827.1_2 - 1.8e-94 316.4 0.0 2.6e-94 315.8 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GATase_6 PF13522.6 AAAP01003827.1_2 - 0.025 14.8 0.0 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain GATase_7 PF13537.6 AAAP01003827.1_2 - 0.18 11.7 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase domain Glu_synthase PF01645.17 AAAP01003827.1_3 - 3.2e-156 520.1 0.1 4.2e-156 519.7 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase GXGXG PF01493.19 AAAP01003827.1_3 - 5.9e-82 273.9 7.3 9.4e-82 273.2 7.3 1.3 1 0 0 1 1 1 1 GXGXG motif Glu_syn_central PF04898.14 AAAP01003827.1_3 - 5.2e-05 22.9 0.7 8.8e-05 22.1 0.4 1.5 2 0 0 2 2 2 1 Glutamate synthase central domain FMN_dh PF01070.18 AAAP01003827.1_3 - 6.9e-05 22.0 0.1 0.00049 19.2 0.2 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Fer4_20 PF14691.6 AAAP01003827.1_4 - 1.6e-25 89.1 1.1 2.2e-25 88.6 1.1 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AAAP01003827.1_4 - 8.2e-11 41.7 0.1 1.4e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003827.1_4 - 6.8e-10 39.0 0.3 1.2e-09 38.2 0.3 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AAAP01003827.1_4 - 2.2e-08 33.9 1.6 3.3e-08 33.3 1.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AAAP01003827.1_4 - 1.6e-07 31.3 0.5 7e-06 25.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01003827.1_4 - 1.7e-07 30.3 1.3 2.8e-07 29.6 1.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 AAAP01003827.1_4 - 5e-06 25.9 0.4 6.3e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 AAAP01003827.1_4 - 1.1e-05 25.0 0.4 1.1e-05 25.0 0.4 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AAAP01003827.1_4 - 1.4e-05 24.4 3.0 2.1e-05 23.8 3.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AAAP01003827.1_4 - 1.7e-05 25.3 0.5 6.6e-05 23.4 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AAAP01003827.1_4 - 1.8e-05 24.2 0.7 3e-05 23.5 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 AAAP01003827.1_4 - 0.00016 21.0 0.3 0.0011 18.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAAP01003827.1_4 - 0.00017 20.9 0.1 0.00026 20.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 AAAP01003827.1_4 - 0.0016 18.4 0.3 0.0023 17.8 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAAP01003827.1_4 - 0.0027 17.0 0.5 0.0038 16.5 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AAAP01003827.1_4 - 0.0066 16.9 0.4 0.013 15.9 0.2 1.6 2 0 0 2 2 1 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 AAAP01003827.1_4 - 0.0079 15.1 1.2 0.012 14.5 1.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 AAAP01003827.1_4 - 0.012 15.6 1.2 0.016 15.2 0.2 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAAP01003827.1_4 - 0.014 14.5 1.1 0.021 13.9 1.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DJ-1_PfpI PF01965.24 AAAP01003827.1_4 - 0.022 14.6 0.4 0.1 12.4 0.2 2.0 1 1 1 2 2 2 0 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.23 AAAP01003827.1_4 - 0.029 14.4 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 AAAP01003827.1_4 - 0.036 12.5 0.0 0.048 12.1 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like TrkA_N PF02254.18 AAAP01003827.1_4 - 0.048 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Fer4_9 PF13187.6 AAAP01003827.1_4 - 0.67 10.2 7.2 0.78 10.0 2.1 2.0 1 1 2 3 3 3 0 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 AAAP01003827.1_5 - 2.3e-08 33.6 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase sCache_2 PF17200.4 AAAP01003827.1_6 - 1.5e-42 145.1 0.1 5.5e-42 143.3 0.1 2.0 1 0 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003827.1_6 - 7.5e-42 143.5 0.2 3.8e-41 141.2 0.0 2.1 2 0 0 2 2 2 1 Cache domain MCPsignal PF00015.21 AAAP01003827.1_6 - 1.1e-32 113.2 22.2 1.1e-32 113.2 22.2 3.0 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Cache_3-Cache_2 PF17201.4 AAAP01003827.1_6 - 7.8e-10 38.5 0.6 3.7e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain DUF1664 PF07889.12 AAAP01003827.1_6 - 0.00029 20.8 7.2 0.12 12.4 0.7 3.5 2 2 0 2 2 2 2 Protein of unknown function (DUF1664) HAMP PF00672.25 AAAP01003827.1_6 - 0.00043 20.6 0.1 0.00043 20.6 0.1 3.7 4 0 0 4 4 3 1 HAMP domain DUF948 PF06103.11 AAAP01003827.1_6 - 0.0021 18.3 23.2 0.56 10.5 1.5 5.7 3 1 3 6 6 6 4 Bacterial protein of unknown function (DUF948) Collagen_mid PF15984.5 AAAP01003827.1_6 - 0.046 13.5 14.2 0.88 9.3 3.7 2.5 1 1 0 2 2 2 0 Bacterial collagen, middle region DUF2574 PF10836.8 AAAP01003827.1_6 - 0.069 13.0 1.3 0.57 10.1 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2574) DUF3450 PF11932.8 AAAP01003827.1_6 - 0.076 12.3 9.6 1.3 8.3 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 AAAP01003827.1_6 - 0.091 12.4 13.6 1.2 8.8 2.1 2.7 1 1 0 2 2 2 0 Laminin Domain I LXG PF04740.12 AAAP01003827.1_6 - 0.17 11.6 6.3 4 7.1 0.8 3.3 2 2 0 2 2 2 0 LXG domain of WXG superfamily PIN_8 PF18476.1 AAAP01003827.1_6 - 0.21 11.4 3.6 3.1 7.6 0.3 2.5 1 1 1 2 2 2 0 PIN like domain HTH_15 PF12324.8 AAAP01003827.1_6 - 2.3 8.3 4.8 1.1 9.3 0.2 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase TMP_2 PF06791.13 AAAP01003827.1_6 - 5.8 6.5 42.4 0.02 14.6 5.5 4.1 2 1 2 4 4 4 0 Prophage tail length tape measure protein dCache_1 PF02743.18 AAAP01003827.1_6 - 6.1 6.6 5.5 4.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Cache domain Laminin_II PF06009.12 AAAP01003827.1_6 - 8.8 6.3 18.6 3.7 7.6 0.2 3.9 2 1 4 6 6 6 0 Laminin Domain II NnrS PF05940.12 AAAP01003827.1_7 - 2.3e-106 356.3 68.5 2.6e-106 356.1 68.5 1.0 1 0 0 1 1 1 1 NnrS protein SAM_adeno_trans PF01887.16 AAAP01003827.1_8 - 2.3e-64 217.0 0.0 2.6e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase DsbG_N PF18257.1 AAAP01003827.1_8 - 0.24 11.6 0.0 0.37 11.0 0.0 1.2 1 0 0 1 1 1 0 Disulfide isomerase DsbG N-terminal Lactamase_B_2 PF12706.7 AAAP01003827.1_9 - 6.5e-14 51.9 0.0 8.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AAAP01003827.1_9 - 0.00087 19.4 2.8 0.0018 18.3 2.8 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily ROS_MUCR PF05443.11 AAAP01003827.1_10 - 2e-50 170.0 0.0 2.3e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein LacAB_rpiB PF02502.18 AAAP01003827.1_11 - 9.3e-54 181.2 0.0 1.1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase ACP_syn_III_C PF08541.10 AAAP01003827.1_11 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cytidylate_kin PF02224.18 AAAP01003827.1_11 - 0.15 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase SHMT PF00464.19 AAAP01003827.1_12 - 1.8e-129 431.9 0.1 2.2e-129 431.6 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 AAAP01003827.1_12 - 1.9e-05 24.2 0.2 2.5e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AAAP01003827.1_12 - 1.9e-05 24.0 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AAAP01003827.1_12 - 0.017 14.4 0.1 0.04 13.2 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase SHMT PF00464.19 AAAP01003827.1_13 - 9.5e-31 106.8 0.0 1.1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase ATP-cone PF03477.16 AAAP01003827.1_14 - 8.7e-19 67.9 0.1 1.1e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 ATP cone domain TF_Zn_Ribbon PF08271.12 AAAP01003827.1_14 - 4.6e-05 22.8 2.2 0.19 11.2 0.3 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AAAP01003827.1_14 - 0.0015 17.9 0.5 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Lar_restr_allev PF14354.6 AAAP01003827.1_14 - 0.002 18.5 1.4 0.0058 17.0 1.5 1.7 1 1 0 1 1 1 1 Restriction alleviation protein Lar TFIIS_C PF01096.18 AAAP01003827.1_14 - 0.0024 17.7 1.1 0.046 13.6 0.1 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.6 AAAP01003827.1_14 - 0.005 17.5 2.3 1.5 9.6 0.1 2.6 2 0 0 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ogr_Delta PF04606.12 AAAP01003827.1_14 - 0.011 15.7 0.3 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger UPF0547 PF10571.9 AAAP01003827.1_14 - 0.011 15.8 4.0 0.72 10.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF3268 PF11672.8 AAAP01003827.1_14 - 0.082 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain A2L_zn_ribbon PF08792.10 AAAP01003827.1_14 - 0.13 12.0 0.4 7.1 6.5 0.0 2.6 3 0 0 3 3 3 0 A2L zinc ribbon domain Cys_rich_CPXG PF14255.6 AAAP01003827.1_14 - 0.22 11.4 0.7 9.8 6.2 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG Zn-ribbon_8 PF09723.10 AAAP01003827.1_14 - 0.3 11.2 4.8 1.5 9.0 4.7 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AAAP01003827.1_14 - 0.3 11.1 6.0 3.7 7.6 0.7 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 AAAP01003827.1_14 - 0.38 10.8 3.7 2.5 8.2 0.2 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_9 PF14369.6 AAAP01003827.1_14 - 0.4 11.0 0.1 0.4 11.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon DUF35_N PF12172.8 AAAP01003827.1_14 - 0.73 9.8 5.5 2.2 8.2 0.7 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 AAAP01003827.1_14 - 1.1 9.0 4.8 12 5.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AAAP01003827.1_14 - 4 7.5 6.8 1.2 9.1 3.2 2.0 2 1 0 2 2 2 0 Nudix N-terminal RibD_C PF01872.17 AAAP01003827.1_15 - 9.8e-50 169.2 0.1 1.4e-49 168.6 0.1 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AAAP01003827.1_15 - 5.6e-17 61.5 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AAAP01003827.1_15 - 2.1e-11 43.8 0.0 3.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 AAAP01003827.1_15 - 0.00043 20.1 0.0 0.0013 18.6 0.0 1.8 2 1 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase Lum_binding PF00677.17 AAAP01003827.1_16 - 1.9e-48 162.4 0.3 1.6e-24 85.7 0.0 2.0 2 0 0 2 2 2 2 Lumazine binding domain RGM_C PF06534.13 AAAP01003827.1_16 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus DHBP_synthase PF00926.19 AAAP01003827.1_17 - 1.4e-80 269.4 0.4 1.7e-80 269.1 0.4 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AAAP01003827.1_17 - 2.3e-11 43.6 0.0 5.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1643 PF07799.12 AAAP01003827.1_17 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) DMRL_synthase PF00885.19 AAAP01003827.1_18 - 6.4e-37 126.5 0.0 7.1e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase NusB PF01029.18 AAAP01003827.1_19 - 6.5e-27 94.4 0.0 7.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 NusB family AIRS PF00586.24 AAAP01003827.1_20 - 2.7e-22 79.2 1.1 2.7e-21 76.0 0.1 2.6 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AAAP01003827.1_20 - 3.2e-12 46.8 0.3 4.9e-12 46.2 0.3 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain LapA_dom PF06305.11 AAAP01003827.1_21 - 2 8.3 3.7 3.7 7.4 3.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain H_PPase PF03030.16 AAAP01003827.1_22 - 5e-263 874.6 56.3 5.8e-263 874.4 56.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase SmpA_OmlA PF04355.13 AAAP01003827.1_23 - 2.8e-18 65.5 0.0 3.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family Ubiq_cyt_C_chap PF03981.12 AAAP01003827.1_24 - 8.5e-44 149.1 2.2 1.1e-43 148.8 2.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF4605 PF15378.6 AAAP01003827.1_24 - 0.2 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) YceD PF02620.17 AAAP01003827.1_25 - 8.6e-13 48.5 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Ribosomal_L32p PF01783.23 AAAP01003827.1_26 - 2.2e-28 98.3 3.9 2.4e-28 98.1 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family OrfB_Zn_ribbon PF07282.11 AAAP01003827.1_26 - 0.002 18.0 2.2 0.0023 17.8 1.2 1.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain PolC_DP2 PF03833.13 AAAP01003827.1_26 - 0.14 10.0 0.5 0.15 9.9 0.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.6 AAAP01003827.1_26 - 0.24 10.8 8.5 1.1 8.8 8.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain YhfH PF14149.6 AAAP01003827.1_26 - 0.63 10.1 5.3 3.5 7.7 0.2 2.4 1 1 1 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.10 AAAP01003827.1_26 - 0.9 9.7 4.4 3.1 8.0 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 AAAP01003827.1_26 - 3 7.4 8.1 37 4.0 8.1 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding DUF1610 PF07754.11 AAAP01003827.1_26 - 5.4 7.1 10.0 1.2 9.2 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) FA_synthesis PF02504.15 AAAP01003827.1_27 - 2e-107 359.0 0.7 2.2e-107 358.8 0.7 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein ACP_syn_III_C PF08541.10 AAAP01003827.1_28 - 1.4e-37 127.7 0.0 4.7e-37 126.0 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AAAP01003827.1_28 - 3e-35 119.9 0.8 7e-35 118.7 0.8 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AAAP01003827.1_28 - 6.6e-09 35.5 2.3 4.1e-08 32.9 0.3 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AAAP01003827.1_28 - 0.0018 17.7 0.0 0.0044 16.3 0.0 1.7 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ketoacyl-synt PF00109.26 AAAP01003827.1_28 - 0.05 13.2 5.1 0.056 13.0 1.3 2.6 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Bac_DNA_binding PF00216.21 AAAP01003827.1_29 - 3.1e-28 97.8 0.0 3.5e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003827.1_29 - 3.1e-09 37.0 0.0 3.5e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 AAAP01003827.1_29 - 0.031 14.4 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 AAAP01003827.1_29 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 MerR_1 PF13411.6 AAAP01003827.1_30 - 3.3e-24 84.8 0.3 5.2e-24 84.1 0.0 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AAAP01003827.1_30 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein HTH_Tnp_1 PF01527.20 AAAP01003827.1_30 - 0.00091 19.5 0.0 0.02 15.2 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_17 PF12728.7 AAAP01003827.1_30 - 0.045 13.9 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain AKAP7_RIRII_bdg PF10470.9 AAAP01003827.1_30 - 0.11 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein TPR_2 PF07719.17 AAAP01003827.1_31 - 4.4e-54 176.3 25.8 6.3e-06 25.9 0.0 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003827.1_31 - 6e-54 177.8 11.1 7.4e-08 31.9 0.1 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003827.1_31 - 6.9e-48 160.1 12.9 4.7e-08 32.6 0.2 9.5 1 1 9 10 10 10 7 TPR repeat TPR_16 PF13432.6 AAAP01003827.1_31 - 8.1e-47 157.6 48.2 9.7e-11 42.1 2.9 6.3 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003827.1_31 - 3.5e-38 129.9 28.4 1.2e-09 38.6 3.1 6.1 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003827.1_31 - 7.1e-37 122.5 2.3 0.00015 21.7 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003827.1_31 - 1.5e-35 121.3 28.0 7.5e-08 32.6 0.0 7.0 4 2 1 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003827.1_31 - 7.3e-32 107.3 47.8 0.00022 21.8 0.2 10.2 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003827.1_31 - 1.3e-28 97.2 11.8 0.007 16.7 0.0 9.1 11 0 0 11 11 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003827.1_31 - 6.9e-27 91.5 10.9 0.0017 18.2 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003827.1_31 - 8.8e-22 75.4 42.0 0.0038 17.7 0.3 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003827.1_31 - 7.6e-21 74.0 39.1 1.1e-06 28.7 0.6 6.9 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003827.1_31 - 1.7e-17 62.8 14.5 0.0028 18.2 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003827.1_31 - 3.3e-16 59.3 0.1 0.0034 17.6 0.0 4.9 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AAAP01003827.1_31 - 1.5e-14 53.3 34.2 0.0057 16.5 0.7 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003827.1_31 - 2.9e-09 37.1 8.8 0.017 15.4 0.2 6.5 2 1 4 7 7 7 2 Tetratricopeptide repeat DUF3856 PF12968.7 AAAP01003827.1_31 - 1.2e-07 31.9 5.1 0.42 10.7 0.1 5.0 3 2 1 4 4 4 2 Domain of Unknown Function (DUF3856) BTAD PF03704.17 AAAP01003827.1_31 - 4.4e-07 30.4 23.2 0.0031 17.9 4.7 5.1 1 1 4 5 5 5 2 Bacterial transcriptional activator domain TPR_3 PF07720.12 AAAP01003827.1_31 - 5e-07 29.6 0.7 19 5.3 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AAAP01003827.1_31 - 9.3e-05 22.4 0.1 0.29 11.2 0.0 3.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 AAAP01003827.1_31 - 0.00015 20.8 0.1 0.037 13.0 0.1 3.6 2 2 2 4 4 4 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 AAAP01003827.1_31 - 0.00021 20.8 12.6 0.03 13.7 2.0 4.6 2 1 3 5 5 5 2 MalT-like TPR region TPR_15 PF13429.6 AAAP01003827.1_31 - 0.002 17.4 9.6 4.5 6.4 0.0 5.1 2 2 3 5 5 5 1 Tetratricopeptide repeat TPPII_N PF12583.8 AAAP01003827.1_31 - 0.0028 18.2 0.3 4.3 7.9 0.0 2.5 2 0 0 2 2 2 2 Tripeptidyl peptidase II N terminal PPR PF01535.20 AAAP01003827.1_31 - 0.0072 16.5 5.2 2.3 8.7 0.0 5.4 7 0 0 7 7 5 1 PPR repeat RPN7 PF10602.9 AAAP01003827.1_31 - 0.075 12.7 4.2 18 5.0 0.1 4.7 4 1 2 6 6 6 0 26S proteasome subunit RPN7 PknG_TPR PF16918.5 AAAP01003827.1_31 - 0.099 11.4 1.7 4.2 6.0 0.0 2.3 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat NRBF2_MIT PF17169.4 AAAP01003827.1_31 - 0.37 11.0 3.5 18 5.6 0.3 4.0 3 1 2 5 5 4 0 MIT domain of nuclear receptor-binding factor 2 TPR_21 PF09976.9 AAAP01003827.1_31 - 4.7 6.9 14.4 0.74 9.5 0.5 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat-like domain Molydop_binding PF01568.21 AAAP01003828.1_1 - 1.4e-19 70.2 0.0 2.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Nmad3 PF18754.1 AAAP01003828.1_1 - 0.086 12.4 0.1 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 Nucleotide modification associated domain 3 Fer4_11 PF13247.6 AAAP01003828.1_2 - 9e-32 109.2 7.3 9e-32 109.2 7.3 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003828.1_2 - 8.2e-09 35.9 14.7 8.2e-05 23.1 6.4 3.4 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003828.1_2 - 5e-08 32.9 21.8 8e-05 22.7 4.8 3.3 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003828.1_2 - 3.4e-05 23.9 23.2 0.12 12.6 11.7 3.3 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003828.1_2 - 3.6e-05 23.6 21.8 0.011 15.7 1.2 4.1 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003828.1_2 - 0.0055 16.8 13.2 0.011 15.9 5.3 3.0 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003828.1_2 - 0.01 15.6 24.2 0.069 13.0 0.5 4.9 5 0 0 5 5 5 0 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003828.1_2 - 0.011 16.7 18.8 0.7 10.9 1.2 3.7 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAAP01003828.1_2 - 0.018 15.6 20.5 0.39 11.3 0.4 3.8 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003828.1_2 - 0.043 14.4 11.7 0.39 11.3 0.1 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AAAP01003828.1_2 - 0.076 13.8 0.4 0.076 13.8 0.4 3.1 4 0 0 4 4 3 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 AAAP01003828.1_2 - 0.099 13.2 1.5 0.099 13.2 1.5 4.5 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003828.1_2 - 0.66 11.0 32.9 0.14 13.2 4.0 4.3 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003828.1_2 - 1.3 9.2 31.1 0.69 10.1 3.6 4.5 4 2 0 4 4 4 0 4Fe-4S binding domain Nitrate_red_del PF02613.15 AAAP01003828.1_3 - 5.3e-23 81.5 0.1 8.6e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 Nitrate reductase delta subunit Cytochrom_C PF00034.21 AAAP01003828.1_4 - 2.7e-08 34.8 0.0 1.9e-07 32.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003828.1_4 - 6.5e-08 32.8 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C1 PF02167.15 AAAP01003828.1_4 - 0.015 15.1 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Cupin_2 PF07883.11 AAAP01003828.1_5 - 6.8e-15 54.6 0.2 1.2e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 AAAP01003828.1_5 - 0.00053 19.9 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 AAAP01003828.1_5 - 0.0045 16.9 0.1 0.0088 16.0 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 AAAP01003828.1_5 - 0.012 15.3 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 AAAP01003828.1_5 - 0.016 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Sigma54_activat PF00158.26 AAAP01003828.1_6 - 5.9e-64 214.8 0.4 8.2e-64 214.3 0.4 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AAAP01003828.1_6 - 9.2e-26 90.2 0.3 2.1e-25 89.1 0.3 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AAAP01003828.1_6 - 2.1e-21 76.5 0.0 5.6e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01003828.1_6 - 1.2e-11 44.2 0.1 4.2e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA PF00004.29 AAAP01003828.1_6 - 9.9e-07 29.2 0.0 4.3e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003828.1_6 - 6.6e-06 26.2 0.1 1.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AAAP01003828.1_6 - 1.8e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AAAP01003828.1_6 - 0.0018 17.7 0.7 0.025 14.0 0.7 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI OKR_DC_1_N PF03709.15 AAAP01003828.1_6 - 0.0091 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_30 PF13604.6 AAAP01003828.1_6 - 0.072 12.8 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain FleQ PF06490.11 AAAP01003828.1_6 - 0.12 12.7 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ PK_C PF02887.16 AAAP01003828.1_6 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain HATPase_c PF02518.26 AAAP01003828.1_7 - 1.3e-21 77.2 0.1 2.2e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01003828.1_7 - 4.7e-05 23.2 0.0 9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAAP01003828.1_7 - 0.046 13.7 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain dCache_1 PF02743.18 AAAP01003828.1_7 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cache domain CZB PF13682.6 AAAP01003828.1_8 - 9.9e-22 77.2 3.6 5e-10 39.7 0.5 2.3 2 0 0 2 2 2 2 Chemoreceptor zinc-binding domain cNMP_binding PF00027.29 AAAP01003828.1_9 - 4.2e-12 46.0 0.0 8.8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003828.1_9 - 3.4e-08 33.4 0.2 8.8e-08 32.0 0.2 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003828.1_9 - 9.6e-05 22.0 0.2 0.00027 20.5 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family Phage_integrase PF00589.22 AAAP01003828.1_11 - 1e-06 28.6 0.0 2.8e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 AAAP01003828.1_11 - 0.00053 20.4 0.1 0.043 14.3 0.0 2.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 AAAP01003828.1_11 - 0.0049 17.1 0.1 1.3 9.3 0.0 2.6 1 1 1 2 2 2 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AAAP01003828.1_11 - 0.013 15.8 0.2 2.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Phage integrase SAM-like domain Asn_synthase PF00733.21 AAAP01003828.1_12 - 7e-64 216.7 0.6 8.6e-64 216.4 0.6 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003828.1_12 - 4e-41 139.8 0.0 6.5e-41 139.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003828.1_12 - 1.1e-35 122.7 0.4 4.4e-35 120.8 0.0 2.1 3 0 0 3 3 3 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAAP01003828.1_12 - 0.0072 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 AAAP01003828.1_12 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Glycos_transf_2 PF00535.26 AAAP01003828.1_14 - 7e-26 91.0 0.0 9.6e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003828.1_14 - 9e-12 45.4 0.2 1.2e-11 45.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003828.1_14 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003828.1_14 - 0.0048 16.4 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF808 PF05661.12 AAAP01003828.1_14 - 0.044 12.8 0.2 0.52 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF808) Radical_SAM PF04055.21 AAAP01003828.1_16 - 2.3e-22 80.1 0.1 5.6e-22 78.9 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003828.1_16 - 3.4e-10 40.0 0.0 7.4e-10 38.9 0.0 1.6 2 0 0 2 2 2 1 B12 binding domain Closter_coat PF01785.17 AAAP01003828.1_16 - 0.22 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Closterovirus coat protein CsiV PF10972.8 AAAP01003828.1_18 - 0.17 11.6 0.0 0.19 11.4 0.0 1.0 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV LPG_synthase_TM PF03706.13 AAAP01003828.1_19 - 9.2e-27 94.3 46.0 1.2e-26 94.0 46.0 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Methyltransf_11 PF08241.12 AAAP01003828.1_20 - 3.3e-24 85.4 0.0 5.3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003828.1_20 - 3.9e-24 85.2 0.0 6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003828.1_20 - 9.4e-20 71.0 0.0 1.3e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003828.1_20 - 3e-15 56.4 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003828.1_20 - 2.6e-14 53.8 0.0 4.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003828.1_20 - 5.3e-14 52.1 0.0 7.6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AAAP01003828.1_20 - 4.6e-08 32.8 0.0 6.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AAAP01003828.1_20 - 4.3e-05 22.9 0.0 5.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 AAAP01003828.1_20 - 9.4e-05 21.9 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 AAAP01003828.1_20 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 AAAP01003828.1_20 - 0.00073 18.2 0.0 0.00098 17.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 AAAP01003828.1_20 - 0.0035 17.0 0.0 0.0048 16.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 AAAP01003828.1_20 - 0.013 14.5 0.0 0.026 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 AAAP01003828.1_20 - 0.027 14.3 0.0 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.19 AAAP01003828.1_20 - 0.046 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AAAP01003828.1_20 - 0.096 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 AAAP01003828.1_20 - 0.14 11.8 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TauE PF01925.19 AAAP01003828.1_21 - 1.1e-35 123.4 37.8 1.3e-35 123.1 37.8 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE FCD PF07729.12 AAAP01003828.1_22 - 1.1e-28 100.2 9.5 1.8e-28 99.5 9.5 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01003828.1_22 - 3.2e-16 58.7 0.0 6.5e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 AAAP01003828.1_22 - 0.025 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_CodY PF08222.11 AAAP01003828.1_22 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_24 PF13412.6 AAAP01003828.1_22 - 0.19 11.3 0.5 0.97 9.1 0.0 2.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding MadL PF03817.13 AAAP01003828.1_23 - 8.4e-45 151.6 13.4 9.7e-45 151.4 13.4 1.0 1 0 0 1 1 1 1 Malonate transporter MadL subunit YobH PF13996.6 AAAP01003828.1_23 - 0.06 13.4 1.3 0.11 12.5 1.3 1.5 1 0 0 1 1 1 0 YobH-like protein Claudin_2 PF13903.6 AAAP01003828.1_23 - 0.32 10.7 5.6 0.2 11.4 4.2 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MadM PF03818.13 AAAP01003828.1_24 - 2.8e-23 81.5 1.8 2.8e-23 81.5 1.8 2.9 3 0 0 3 3 3 1 Malonate/sodium symporter MadM subunit BCAS3 PF12490.8 AAAP01003828.1_24 - 0.29 10.6 0.1 0.43 10.1 0.1 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Mal_decarbox_Al PF16957.5 AAAP01003828.1_25 - 4.4e-70 236.6 0.0 4.9e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter MFS_1 PF07690.16 AAAP01003829.1_1 - 4.5e-08 32.4 10.2 4.7e-08 32.3 10.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 AAAP01003829.1_1 - 2.9e-06 26.0 6.6 3e-06 25.9 6.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 AAAP01003829.1_1 - 0.018 13.9 1.0 0.02 13.7 1.0 1.0 1 0 0 1 1 1 0 MFS_1 like family HATPase_c PF02518.26 AAAP01003829.1_2 - 1.5e-22 80.2 0.0 8.8e-20 71.3 0.0 2.6 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003829.1_2 - 1.3e-09 37.9 1.2 4.9e-09 36.1 1.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003829.1_2 - 0.0025 17.8 0.1 0.14 12.1 0.0 2.9 2 1 1 3 3 3 1 Histidine kinase-like ATPase domain HAMP PF00672.25 AAAP01003829.1_2 - 0.019 15.3 2.1 0.02 15.3 0.2 2.1 2 0 0 2 2 2 0 HAMP domain Response_reg PF00072.24 AAAP01003829.1_3 - 8.4e-21 74.2 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003829.1_3 - 8.6e-19 67.4 0.3 5.8e-18 64.8 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal RNase_E_G PF10150.9 AAAP01003829.1_6 - 7.1e-95 317.5 0.6 1.1e-94 316.9 0.6 1.3 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AAAP01003829.1_6 - 2.6e-05 24.4 0.7 0.00058 20.1 0.0 2.9 3 0 0 3 3 3 1 S1 RNA binding domain Lar_restr_allev PF14354.6 AAAP01003829.1_6 - 0.14 12.5 0.0 0.5 10.8 0.0 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar AMIN PF11741.8 AAAP01003829.1_7 - 2.6e-07 30.7 0.0 1.8e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 AMIN domain Amidase_3 PF01520.18 AAAP01003829.1_8 - 5.5e-51 173.1 0.0 1.4e-50 171.8 0.0 1.6 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Transgly PF00912.22 AAAP01003829.1_10 - 7.2e-61 204.7 0.0 9.8e-61 204.3 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SHOCT PF09851.9 AAAP01003829.1_10 - 0.036 13.8 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain Transpeptidase PF00905.22 AAAP01003829.1_11 - 3.4e-38 131.6 0.0 2.6e-37 128.7 0.0 2.2 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain PCB_OB PF17092.5 AAAP01003829.1_11 - 9.2e-14 52.1 0.0 1.5e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain Response_reg PF00072.24 AAAP01003829.1_12 - 1.2e-25 89.9 0.1 1.3e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain UDPGP PF01704.18 AAAP01003829.1_12 - 0.06 12.0 0.2 0.074 11.7 0.2 1.1 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase POR PF01558.18 AAAP01003829.1_13 - 4.5e-42 144.1 0.2 5.3e-42 143.9 0.2 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase eIF-5a PF01287.20 AAAP01003829.1_13 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold HTH_38 PF13936.6 AAAP01003829.1_13 - 0.16 11.7 0.0 9 6.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TPP_enzyme_C PF02775.21 AAAP01003829.1_14 - 1.3e-24 86.7 0.1 2.6e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 AAAP01003829.1_14 - 2.8e-14 53.4 0.8 4.9e-14 52.6 0.8 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer4_10 PF13237.6 AAAP01003829.1_14 - 9e-06 25.7 9.7 9e-06 25.7 9.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003829.1_14 - 2e-05 24.7 9.2 2e-05 24.7 9.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003829.1_14 - 3.6e-05 23.8 10.3 0.035 14.2 1.0 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003829.1_14 - 9.1e-05 23.0 9.9 9.1e-05 23.0 9.9 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003829.1_14 - 0.00017 21.3 18.9 0.0016 18.2 3.2 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain DXP_synthase_N PF13292.6 AAAP01003829.1_14 - 0.00025 20.4 0.3 0.00025 20.4 0.3 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Fer4_8 PF13183.6 AAAP01003829.1_14 - 0.00044 20.6 8.3 0.0013 19.2 8.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003829.1_14 - 0.00074 19.5 22.9 0.0021 18.1 3.8 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain TPP_enzyme_N PF02776.18 AAAP01003829.1_14 - 0.0013 18.4 0.3 0.0025 17.4 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transket_pyr PF02779.24 AAAP01003829.1_14 - 0.011 15.4 0.2 0.11 12.1 0.1 2.4 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain Fer4_6 PF12837.7 AAAP01003829.1_14 - 0.013 15.6 20.3 0.018 15.1 1.9 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 AAAP01003829.1_14 - 0.022 15.5 5.1 0.31 11.8 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_16 PF13484.6 AAAP01003829.1_14 - 0.46 11.4 13.6 1.7 9.6 3.3 2.7 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAAP01003829.1_14 - 1.5 9.4 12.9 1.5 9.5 10.0 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003829.1_14 - 5.2 8.0 12.7 5.4 7.9 2.5 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain LysR_substrate PF03466.20 AAAP01003829.1_15 - 1e-35 123.0 8.1 1.5e-35 122.5 8.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003829.1_15 - 9.4e-22 76.7 0.2 4.6e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAAP01003829.1_15 - 0.0049 16.7 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_30 PF13556.6 AAAP01003829.1_15 - 0.015 15.1 0.1 0.04 13.7 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAAP01003829.1_15 - 0.018 15.1 0.2 0.061 13.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain GHMP_kinases_C PF08544.13 AAAP01003829.1_15 - 0.11 12.8 0.2 14 6.2 0.0 3.2 2 1 1 3 3 3 0 GHMP kinases C terminal BLACT_WH PF17778.1 AAAP01003829.1_15 - 0.15 12.1 1.7 3.7 7.6 1.3 2.4 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Acyl-CoA_dh_N PF02771.16 AAAP01003829.1_16 - 5.2e-35 120.5 0.0 1e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 AAAP01003829.1_16 - 2.1e-25 89.7 0.8 3.3e-25 89.1 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003829.1_16 - 0.00017 21.7 0.0 0.00084 19.5 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAAP01003829.1_16 - 0.00031 21.0 0.3 0.001 19.4 0.3 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 AAAP01003829.1_16 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ETF PF01012.21 AAAP01003829.1_17 - 4.9e-50 170.0 5.8 6e-50 169.6 5.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CoA_binding_2 PF13380.6 AAAP01003829.1_17 - 0.16 12.5 1.5 0.24 11.9 0.3 1.9 2 0 0 2 2 2 0 CoA binding domain ETF PF01012.21 AAAP01003829.1_18 - 3.5e-38 131.3 13.1 5.9e-38 130.6 13.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 AAAP01003829.1_18 - 1.6e-36 124.2 0.4 1.6e-36 124.2 0.4 2.8 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain Acyl-CoA_dh_1 PF00441.24 AAAP01003829.1_19 - 7.4e-27 94.4 4.1 2.7e-26 92.6 4.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003829.1_19 - 2.8e-16 59.5 0.0 6.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AAAP01003829.1_19 - 1e-14 55.1 0.1 4.2e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 AAAP01003829.1_19 - 1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_C PF12806.7 AAAP01003829.1_19 - 2.1e-10 40.8 3.9 4.5e-10 39.7 3.1 2.0 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_2 PF08028.11 AAAP01003829.1_19 - 2.5e-05 24.5 1.8 2.5e-05 24.5 1.8 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_C PF12806.7 AAAP01003829.1_20 - 1.1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Response_reg PF00072.24 AAAP01003829.1_21 - 2e-28 98.8 0.9 2.3e-28 98.6 0.9 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003829.1_22 - 3.4e-25 88.7 0.0 5.4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003829.1_22 - 2.1e-09 37.3 0.1 5e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003829.1_22 - 3.8e-06 26.9 0.3 1.1e-05 25.4 0.0 2.0 2 1 0 3 3 3 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003829.1_22 - 0.0011 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01003829.1_22 - 0.0064 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 GHKL domain CheX PF13690.6 AAAP01003829.1_23 - 3.6e-15 55.9 0.0 5.2e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX ProRS-C_2 PF09181.10 AAAP01003829.1_23 - 0.15 12.2 0.1 2.8 8.1 0.1 2.6 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Response_reg PF00072.24 AAAP01003829.1_24 - 8.4e-13 48.5 0.0 9.5e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AAAP01003829.1_25 - 0.00091 19.4 0.0 0.00091 19.4 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF4810 PF16068.5 AAAP01003830.1_1 - 3.2e-11 43.6 0.3 6.6e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) TPR_7 PF13176.6 AAAP01003830.1_1 - 0.0011 18.8 0.3 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003830.1_1 - 0.0038 17.2 1.7 0.005 16.9 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003830.1_1 - 0.0048 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003830.1_1 - 0.0071 17.1 0.3 0.025 15.4 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003830.1_1 - 0.01 16.4 0.9 0.035 14.8 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003830.1_1 - 0.018 15.7 0.1 0.018 15.7 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 AAAP01003830.1_1 - 0.074 13.3 0.1 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.6 AAAP01003830.1_1 - 0.084 13.2 0.3 0.13 12.5 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF799 PF05643.11 AAAP01003830.1_2 - 3.1e-35 121.5 0.0 3.4e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Putative bacterial lipoprotein (DUF799) Proteasome PF00227.26 AAAP01003830.1_3 - 1.3e-22 80.2 1.6 3.8e-22 78.7 1.6 1.6 1 1 0 1 1 1 1 Proteasome subunit AAA_2 PF07724.14 AAAP01003830.1_4 - 4.9e-44 150.4 0.0 4.4e-36 124.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AAAP01003830.1_4 - 5.3e-15 56.0 0.0 3.3e-06 27.5 0.1 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003830.1_4 - 2.9e-07 30.6 0.2 1.1e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003830.1_4 - 6.5e-06 26.6 3.1 0.00013 22.4 0.8 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 AAAP01003830.1_4 - 7e-06 25.9 0.6 0.0011 18.7 0.1 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AAAP01003830.1_4 - 1e-05 24.8 0.0 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain ClpB_D2-small PF10431.9 AAAP01003830.1_4 - 1.3e-05 25.2 2.9 1.7e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 AAAP01003830.1_4 - 1.8e-05 25.1 0.2 0.00027 21.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 AAAP01003830.1_4 - 0.00021 20.7 0.0 0.0063 15.9 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAAP01003830.1_4 - 0.0008 19.6 0.1 0.0018 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAAP01003830.1_4 - 0.0029 18.2 0.0 0.007 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AAAP01003830.1_4 - 0.0047 16.6 0.0 0.076 12.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 AAAP01003830.1_4 - 0.0058 16.6 0.1 0.96 9.4 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 AAAP01003830.1_4 - 0.0062 16.8 0.3 0.013 15.7 0.3 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 AAAP01003830.1_4 - 0.012 14.9 0.5 0.048 12.9 0.1 1.9 1 1 1 2 2 2 0 TIP49 P-loop domain TniB PF05621.11 AAAP01003830.1_4 - 0.014 14.8 0.2 0.056 12.9 0.0 2.0 2 1 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 AAAP01003830.1_4 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PIN_5 PF08745.11 AAAP01003830.1_4 - 0.026 13.9 0.4 0.07 12.5 0.4 1.7 1 0 0 1 1 1 0 PINc domain ribonuclease ATP-synt_ab PF00006.25 AAAP01003830.1_4 - 0.028 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 AAAP01003830.1_4 - 0.034 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 AAAP01003830.1_4 - 0.055 13.1 0.1 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 AAAP01003830.1_4 - 0.072 12.6 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_lid_3 PF17862.1 AAAP01003830.1_4 - 0.092 12.6 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA+ lid domain RsgA_GTPase PF03193.16 AAAP01003830.1_4 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 AAAP01003830.1_4 - 0.11 12.2 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01003830.1_4 - 0.14 11.4 0.6 0.67 9.2 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 AAAP01003830.1_4 - 0.16 12.0 0.0 3.1 7.9 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 AAAP01003830.1_4 - 0.17 11.6 1.0 0.5 10.1 0.2 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase Roc PF08477.13 AAAP01003830.1_4 - 0.19 11.9 0.0 0.74 10.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cNMP_binding PF00027.29 AAAP01003830.1_5 - 1.3e-11 44.4 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003830.1_5 - 0.054 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_31 PF13560.6 AAAP01003830.1_6 - 3.1e-11 43.5 2.2 7.4e-10 39.0 0.1 2.4 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003830.1_6 - 5.8e-10 39.1 0.1 2.8e-08 33.7 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003830.1_6 - 1.5e-08 34.5 0.0 9.2e-08 32.0 0.0 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_25 PF13413.6 AAAP01003830.1_6 - 1.9e-06 27.6 1.1 3e-06 27.0 0.1 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003830.1_6 - 0.00016 22.0 0.0 0.00055 20.3 0.0 1.9 2 1 1 3 3 3 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AAAP01003830.1_6 - 0.003 17.5 0.0 0.11 12.5 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain Smr PF01713.21 AAAP01003830.1_7 - 1.3e-22 79.9 0.0 2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Smr domain MltA PF03562.17 AAAP01003830.1_9 - 9e-74 248.0 0.0 1.1e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 MltA specific insert domain 3D PF06725.11 AAAP01003830.1_9 - 3.8e-22 78.2 0.0 8.1e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 3D domain Tim44 PF04280.15 AAAP01003830.1_10 - 1.9e-49 167.5 0.0 2.3e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain FxsA PF04186.13 AAAP01003830.1_11 - 7.7e-27 93.6 8.5 9.6e-27 93.3 8.5 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein SecB PF02556.14 AAAP01003830.1_12 - 4e-51 172.6 0.0 4.7e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB RNase_T PF00929.24 AAAP01003830.1_13 - 1.1e-33 117.1 0.0 1.4e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 AAAP01003830.1_13 - 0.0012 18.9 0.0 0.0054 16.7 0.0 1.9 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 AAAP01003830.1_13 - 0.0027 17.4 0.0 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Amidohydro_3 PF07969.11 AAAP01003830.1_13 - 0.1 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family CoaE PF01121.20 AAAP01003830.1_14 - 8.2e-41 139.6 0.0 1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase VEK-30 PF12107.8 AAAP01003830.1_14 - 0.22 11.5 2.8 7.5 6.6 0.9 2.7 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway Shikimate_dh_N PF08501.11 AAAP01003830.1_15 - 2.9e-27 94.8 0.0 4.8e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AAAP01003830.1_15 - 5.6e-08 32.4 0.7 1.3e-07 31.2 0.7 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AAAP01003830.1_15 - 7.8e-08 32.5 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AAAP01003830.1_15 - 0.00018 22.0 0.1 0.00048 20.7 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AAAP01003830.1_15 - 0.0017 18.6 0.3 0.0025 18.1 0.3 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Maf PF02545.14 AAAP01003830.1_16 - 1.6e-35 122.4 0.0 1.8e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF4140 PF13600.6 AAAP01003830.1_16 - 0.018 15.4 0.4 0.028 14.8 0.4 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Kinase-PPPase PF03618.14 AAAP01003830.1_17 - 1e-91 307.3 0.0 1.2e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase TmoB PF06234.12 AAAP01003830.1_17 - 0.095 12.8 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) URO-D PF01208.17 AAAP01003830.1_18 - 3.9e-114 381.4 0.0 4.4e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ferrochelatase PF00762.19 AAAP01003830.1_19 - 1.8e-106 355.8 0.0 2e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 AAAP01003830.1_19 - 0.045 14.1 0.0 14 6.1 0.0 2.8 2 1 1 3 3 3 0 CbiX GAF PF01590.26 AAAP01003830.1_19 - 0.11 13.1 0.0 0.27 11.8 0.0 1.6 2 0 0 2 2 2 0 GAF domain UPF0093 PF03653.13 AAAP01003830.1_20 - 4.2e-57 192.5 3.3 4.8e-57 192.3 3.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) SirB PF04247.12 AAAP01003830.1_20 - 0.052 13.6 6.3 0.13 12.3 6.3 1.7 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF4519 PF15012.6 AAAP01003830.1_20 - 0.054 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) CTV_P6 PF06706.11 AAAP01003830.1_20 - 0.17 11.6 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Rho_RNA_bind PF07497.12 AAAP01003830.1_21 - 2.1e-32 110.8 0.0 3.7e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AAAP01003830.1_21 - 5.1e-23 81.8 0.1 7.1e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AAAP01003830.1_21 - 6.5e-18 64.4 0.9 1.9e-17 62.9 0.9 1.9 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain AAA_25 PF13481.6 AAAP01003830.1_21 - 0.00033 20.3 0.1 0.0015 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain OB_RNB PF08206.11 AAAP01003830.1_21 - 0.0011 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_22 PF13401.6 AAAP01003830.1_21 - 0.0015 18.8 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AAAP01003830.1_21 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 AAAP01003830.1_21 - 0.017 15.6 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AAAP01003830.1_21 - 0.09 12.8 0.1 1 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain Terminase_GpA PF05876.12 AAAP01003830.1_21 - 0.19 10.2 0.0 13 4.2 0.0 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) ADH_zinc_N PF00107.26 AAAP01003830.1_23 - 1.8e-29 102.3 0.1 2.9e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AAAP01003830.1_23 - 1.3e-18 68.3 0.0 2.4e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003830.1_23 - 1.1e-10 41.4 0.0 2.5e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 AAAP01003830.1_23 - 0.00078 19.1 0.1 0.81 9.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain DNA_binding_1 PF01035.20 AAAP01003830.1_25 - 3.2e-31 107.3 0.0 4.1e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 AAAP01003830.1_25 - 0.00029 21.6 0.0 0.0023 18.7 0.0 2.1 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Thioredox_DsbH PF03190.15 AAAP01003830.1_26 - 2.4e-70 235.7 0.0 4e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 AAAP01003830.1_26 - 1.9e-07 31.1 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 AAAP01003830.1_26 - 2.4e-05 23.6 0.1 0.51 9.4 0.1 3.1 2 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 AAAP01003830.1_26 - 7.4e-05 22.4 9.5 0.0025 17.4 0.8 3.8 2 1 2 4 4 4 3 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 AAAP01003830.1_26 - 0.16 10.5 0.0 2.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 EAL PF00563.20 AAAP01003831.1_1 - 8.6e-71 238.2 0.1 2.7e-70 236.6 0.0 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AAAP01003831.1_1 - 7.3e-36 123.3 0.0 1.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AAAP01003831.1_1 - 2.3e-20 72.7 0.0 8.5e-08 32.4 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AAAP01003831.1_1 - 1.2e-18 67.1 0.0 3.5e-11 43.1 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01003831.1_1 - 5.3e-17 62.0 0.0 4.6e-10 39.7 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AAAP01003831.1_1 - 2.6e-13 50.2 2.0 1.8e-08 34.6 0.0 4.0 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AAAP01003831.1_1 - 2.1e-07 30.8 0.1 1.7e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 PAS domain TerC PF03741.16 AAAP01003831.1_2 - 1.1e-47 162.1 8.5 1.3e-47 161.8 8.5 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF475 PF04332.15 AAAP01003831.1_2 - 0.0022 17.8 2.3 0.0022 17.8 2.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF475) DUF3470 PF11953.8 AAAP01003831.1_3 - 6.3e-17 61.3 2.5 9.4e-17 60.7 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 AAAP01003831.1_3 - 2.8e-10 39.6 21.7 1.8e-07 30.7 6.4 3.1 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003831.1_3 - 1e-07 32.0 8.8 8.4e-05 22.6 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003831.1_3 - 5.9e-07 29.6 24.9 8.1e-05 22.7 14.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003831.1_3 - 7.2e-07 28.9 14.2 0.0017 18.3 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003831.1_3 - 9.5e-07 29.3 28.4 3.6e-05 24.3 16.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003831.1_3 - 1.6e-06 27.9 19.6 9.7e-05 22.3 5.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003831.1_3 - 2.2e-06 28.5 9.2 0.00073 20.4 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003831.1_3 - 3.8e-06 26.9 11.4 0.0028 17.8 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003831.1_3 - 6.2e-05 23.4 7.4 0.0026 18.1 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003831.1_3 - 7e-05 23.0 14.9 0.00058 20.2 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003831.1_3 - 0.0027 18.2 14.2 0.0064 17.0 1.5 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003831.1_3 - 0.012 16.2 11.8 0.021 15.4 1.3 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_11 PF13247.6 AAAP01003831.1_3 - 0.33 11.1 9.1 2.1 8.5 9.3 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003831.1_3 - 2.1 9.5 20.4 0.81 10.8 7.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 AAAP01003831.1_3 - 4.1 7.6 8.6 1.3 9.2 2.3 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_20 PF14691.6 AAAP01003831.1_3 - 5.8 6.7 14.1 0.22 11.3 3.8 2.1 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster CarD_CdnL_TRCF PF02559.16 AAAP01003831.1_4 - 1.7e-19 70.3 0.0 2.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 CarD-like/TRCF domain DUF4197 PF13852.6 AAAP01003831.1_6 - 3.7e-70 235.7 0.0 4.6e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) TrbC PF04956.13 AAAP01003831.1_6 - 0.12 12.6 0.4 0.25 11.6 0.4 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family GST_C_3 PF14497.6 AAAP01003831.1_7 - 2.2e-12 47.0 0.0 3.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAAP01003831.1_7 - 3.6e-12 46.3 0.0 8.3e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AAAP01003831.1_7 - 5.6e-11 42.6 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003831.1_7 - 5.1e-09 36.3 0.0 9.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003831.1_7 - 3.4e-08 33.4 0.3 6.7e-08 32.5 0.3 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AAAP01003831.1_7 - 3.7e-08 33.7 0.0 7.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 AAAP01003831.1_7 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_ribbon_SprT PF17283.2 AAAP01003831.1_8 - 0.0044 16.9 0.3 0.0062 16.4 0.3 1.2 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DNA_RNApol_7kD PF03604.13 AAAP01003831.1_8 - 0.079 12.6 1.3 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit YABBY PF04690.13 AAAP01003831.1_8 - 0.13 12.9 0.4 0.17 12.5 0.4 1.1 1 0 0 1 1 1 0 YABBY protein G_glu_transpept PF01019.21 AAAP01003831.1_9 - 2.5e-123 412.6 0.0 2.8e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Phage_TAC_11 PF11836.8 AAAP01003831.1_9 - 0.057 13.5 0.6 0.057 13.5 0.6 2.4 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 Pribosyltran PF00156.27 AAAP01003831.1_10 - 3.9e-08 33.0 0.1 7.3e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pox_F12L PF03337.13 AAAP01003831.1_10 - 0.065 11.4 0.0 0.08 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein FUR PF01475.19 AAAP01003831.1_11 - 4.1e-21 75.3 0.0 4.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_Crp_2 PF13545.6 AAAP01003831.1_11 - 0.034 14.1 1.7 0.37 10.8 0.2 2.4 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 AAAP01003831.1_11 - 0.13 12.4 1.3 0.27 11.3 1.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 AAAP01003831.1_11 - 0.17 12.2 0.7 0.4 10.9 0.1 1.8 2 0 0 2 2 2 0 Transposase CoA_transf_3 PF02515.17 AAAP01003831.1_12 - 2.5e-138 461.2 0.1 2.9e-138 461.0 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF4010 PF13194.6 AAAP01003831.1_12 - 0.02 14.6 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Aldedh PF00171.22 AAAP01003831.1_13 - 1.3e-172 574.5 2.2 1.4e-172 574.3 2.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 AAAP01003831.1_13 - 0.0022 17.5 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) HSP70 PF00012.20 AAAP01003831.1_14 - 5.8e-21 74.3 0.2 4e-09 35.2 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 AAAP01003831.1_14 - 1.5e-07 30.6 1.6 0.00018 20.5 0.4 2.9 3 0 0 3 3 3 2 MreB/Mbl protein MurJ PF03023.14 AAAP01003831.1_15 - 1.6e-118 396.2 30.5 2.1e-118 395.8 30.5 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AAAP01003831.1_15 - 3.1e-12 46.8 17.9 3.1e-12 46.8 17.9 4.3 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 AAAP01003831.1_15 - 9e-07 28.7 6.3 9e-07 28.7 6.3 3.3 4 0 0 4 4 4 2 MatE Polysacc_synt_3 PF13440.6 AAAP01003831.1_15 - 0.0001 21.7 2.8 0.0001 21.7 2.8 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein Acetyltransf_1 PF00583.25 AAAP01003831.1_16 - 1.1e-13 51.4 0.1 1.5e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAAP01003831.1_16 - 2.4e-09 37.2 0.0 3.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01003831.1_16 - 2.3e-08 34.4 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AAAP01003831.1_16 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003831.1_16 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 AAAP01003831.1_16 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cupredoxin_1 PF13473.6 AAAP01003831.1_17 - 2.3e-24 85.5 0.0 2.7e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Cupredoxin-like domain Iron_transport PF10634.9 AAAP01003831.1_18 - 1.7e-53 180.8 0.8 2.1e-53 180.5 0.8 1.0 1 0 0 1 1 1 1 Fe2+ transport protein Pyr_redox_2 PF07992.14 AAAP01003832.1_1 - 0.00014 21.3 0.2 0.00016 21.1 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Attacin_N PF03768.15 AAAP01003832.1_1 - 0.017 15.3 0.3 0.024 14.8 0.3 1.3 1 0 0 1 1 1 0 Attacin, N-terminal region HicB_lk_antitox PF15919.5 AAAP01003832.1_1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system LysR_substrate PF03466.20 AAAP01003832.1_2 - 6.4e-38 130.2 0.0 7.9e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003832.1_2 - 7.2e-23 80.3 0.3 1.2e-22 79.6 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AAAP01003832.1_2 - 0.051 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAAP01003832.1_2 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding IMS PF00817.20 AAAP01003832.1_4 - 1.3e-30 106.3 0.0 1.9e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AAAP01003832.1_4 - 3.2e-05 24.6 0.0 7.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cdd1 PF11731.8 AAAP01003832.1_4 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus DUF4113 PF13438.6 AAAP01003832.1_4 - 0.046 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) IMS_HHH PF11798.8 AAAP01003832.1_4 - 0.064 13.6 0.1 0.16 12.4 0.1 1.8 1 0 0 1 1 1 0 IMS family HHH motif DUF1805 PF08827.11 AAAP01003832.1_4 - 0.1 12.9 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DUF4337 PF14235.6 AAAP01003832.1_6 - 8.4e-12 45.5 3.3 8.4e-12 45.5 3.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4337) DUF5134 PF17197.4 AAAP01003832.1_6 - 0.045 13.7 0.5 0.045 13.7 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) DUF2371 PF10177.9 AAAP01003832.1_6 - 0.053 13.7 0.2 6.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF945 PF06097.11 AAAP01003832.1_6 - 0.11 11.6 0.6 0.2 10.7 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) ENOD93 PF03386.14 AAAP01003832.1_6 - 0.23 11.3 3.5 11 6.0 0.3 2.4 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein IMS PF00817.20 AAAP01003832.1_7 - 1.7e-46 157.9 0.0 2.9e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AAAP01003832.1_7 - 2.8e-22 79.6 0.1 1.8e-21 77.0 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AAAP01003832.1_7 - 0.00012 22.1 0.0 0.00033 20.8 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.6 AAAP01003832.1_7 - 0.0072 16.9 0.0 0.025 15.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 AAAP01003832.1_7 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DnaB_bind PF10410.9 AAAP01003832.1_7 - 2.3 8.5 5.6 28 5.0 0.0 3.4 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Methyltransf_11 PF08241.12 AAAP01003832.1_8 - 2.1e-08 34.7 0.2 4.4e-08 33.7 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003832.1_8 - 3.7e-06 26.9 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003832.1_8 - 2.9e-05 24.7 0.2 7.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003832.1_8 - 0.0048 17.6 0.0 0.014 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Hydrolase_4 PF12146.8 AAAP01003832.1_9 - 6.3e-21 74.7 0.0 1.2e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003832.1_9 - 5.3e-17 62.3 0.1 7.7e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003832.1_9 - 1.2e-15 58.8 5.2 1.5e-15 58.4 5.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAAP01003832.1_9 - 1.2e-10 41.3 0.0 5.6e-05 22.7 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AAAP01003832.1_9 - 2.1e-07 30.8 0.2 7.2e-07 29.1 0.2 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 AAAP01003832.1_9 - 9.3e-06 25.6 0.2 1.9e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 AAAP01003832.1_9 - 0.00044 19.9 0.0 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S28 PF05577.12 AAAP01003832.1_9 - 0.0011 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 AAAP01003832.1_9 - 0.002 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 AAAP01003832.1_9 - 0.011 15.4 0.0 6.8 6.3 0.0 2.8 3 0 0 3 3 3 0 Serine hydrolase (FSH1) AXE1 PF05448.12 AAAP01003832.1_9 - 0.016 13.9 0.1 4.8 5.8 0.1 2.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 AAAP01003832.1_9 - 0.067 13.0 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VirJ PF06057.11 AAAP01003832.1_9 - 0.093 12.6 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) BAAT_C PF08840.11 AAAP01003832.1_9 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HATPase_c PF02518.26 AAAP01003832.1_10 - 1.1e-23 83.9 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003832.1_10 - 1.5e-05 25.0 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HPTransfase PF10090.9 AAAP01003832.1_10 - 0.016 15.0 0.1 0.057 13.2 0.0 1.9 1 1 1 2 2 2 0 Histidine phosphotransferase C-terminal domain PAS_7 PF12860.7 AAAP01003832.1_11 - 5.1e-28 97.5 0.0 4.7e-13 49.3 0.0 3.3 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AAAP01003832.1_11 - 5.7e-14 51.8 0.1 0.0013 18.7 0.0 4.2 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AAAP01003832.1_11 - 3.9e-10 40.0 8.8 0.00033 20.9 0.4 4.7 4 1 0 4 4 4 3 PAS fold HisKA PF00512.25 AAAP01003832.1_11 - 2.1e-08 34.1 0.4 1.2e-07 31.6 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003832.1_11 - 3.5e-07 30.2 0.0 1.3 9.1 0.0 3.8 3 1 0 3 3 3 3 PAS fold Sec5 PF15469.6 AAAP01003832.1_11 - 0.24 11.2 0.0 0.42 10.4 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 SNARE_assoc PF09335.11 AAAP01003832.1_12 - 2.8e-09 37.5 7.5 2.8e-09 37.5 7.5 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3169 PF11368.8 AAAP01003832.1_12 - 0.037 13.5 2.5 0.038 13.5 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PT-VENN PF04829.13 AAAP01003832.1_12 - 0.22 11.6 0.5 0.4 10.8 0.5 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif FliJ PF02050.16 AAAP01003832.1_13 - 5.5e-09 36.3 12.7 7.4e-09 35.9 12.7 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein Cob_adeno_trans PF01923.18 AAAP01003832.1_13 - 0.0063 16.7 1.7 0.0099 16.0 1.7 1.3 1 1 0 1 1 1 1 Cobalamin adenosyltransferase DNA_photolyase PF00875.18 AAAP01003832.1_13 - 0.016 15.2 2.2 1.4 8.9 0.0 2.0 1 1 1 2 2 2 0 DNA photolyase Spore_III_AB PF09548.10 AAAP01003832.1_13 - 0.024 14.7 0.3 0.045 13.9 0.3 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF2203 PF09969.9 AAAP01003832.1_13 - 0.21 12.3 4.4 0.24 12.1 1.7 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ATP-synt_ab PF00006.25 AAAP01003832.1_14 - 2.7e-75 252.7 0.0 4e-75 252.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AAAP01003832.1_14 - 3.3e-21 74.9 0.2 5.8e-21 74.1 0.2 1.3 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AAAP01003832.1_14 - 0.0026 18.3 0.8 0.0059 17.1 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 AAAP01003832.1_14 - 0.032 14.7 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 AAAP01003832.1_14 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Response_reg PF00072.24 AAAP01003832.1_15 - 5.7e-29 100.5 0.1 8.4e-29 100.0 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003832.1_15 - 9.9e-21 73.6 0.1 2.5e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HMA PF00403.26 AAAP01003832.1_15 - 0.16 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain ABC1 PF03109.16 AAAP01003832.1_16 - 2.5e-35 121.2 0.0 4.2e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 AAAP01003832.1_16 - 0.00017 21.6 3.1 0.014 15.3 0.4 3.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 AAAP01003832.1_16 - 0.016 14.5 0.0 0.035 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Ubie_methyltran PF01209.18 AAAP01003832.1_17 - 1.4e-80 270.0 0.0 1.6e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AAAP01003832.1_17 - 6.7e-21 74.7 0.0 1.5e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003832.1_17 - 6.8e-20 71.6 0.0 2.6e-19 69.7 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003832.1_17 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003832.1_17 - 1.7e-09 38.3 0.0 2.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003832.1_17 - 2.5e-07 30.7 0.0 4.3e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AAAP01003832.1_17 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 AAAP01003832.1_17 - 0.001 18.7 0.0 0.0059 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AAAP01003832.1_17 - 0.012 14.9 0.0 0.028 13.7 0.0 1.8 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 AAAP01003832.1_17 - 0.069 12.4 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Fapy_DNA_glyco PF01149.24 AAAP01003832.1_18 - 3.4e-32 111.5 0.1 5.2e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AAAP01003832.1_18 - 1e-27 95.9 0.0 1.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AAAP01003832.1_18 - 0.013 15.3 1.9 0.021 14.6 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Prok_Ub PF14454.6 AAAP01003832.1_19 - 0.061 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic Ubiquitin ECH_1 PF00378.20 AAAP01003832.1_20 - 1.9e-89 299.3 2.2 2.2e-89 299.1 2.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003832.1_20 - 5.6e-37 128.0 4.7 5.2e-36 124.8 2.7 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 AAAP01003832.1_20 - 0.047 13.6 0.1 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Ribosomal_S20p PF01649.18 AAAP01003832.1_21 - 7e-28 97.1 7.4 7.8e-28 96.9 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 Bac_DnaA PF00308.18 AAAP01003832.1_22 - 5e-53 180.2 0.1 7.3e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein DnaA_N PF11638.8 AAAP01003832.1_22 - 6.3e-22 77.1 0.0 1.2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 AAAP01003832.1_22 - 9.3e-08 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 AAAP01003832.1_22 - 1.3e-05 25.6 0.0 2.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AAAP01003832.1_22 - 0.0037 16.2 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 AFG1-like ATPase AAA_22 PF13401.6 AAAP01003832.1_22 - 0.0057 16.9 0.2 3.8 7.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain NACHT PF05729.12 AAAP01003832.1_22 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 AAAP01003832.1_22 - 0.0093 16.3 0.5 0.056 13.8 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 AAAP01003832.1_22 - 0.011 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003832.1_22 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 AAAP01003832.1_22 - 0.016 15.2 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 AAAP01003832.1_22 - 0.016 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 AAAP01003832.1_22 - 0.02 14.9 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 AAAP01003832.1_22 - 0.04 13.7 0.3 0.15 11.8 0.0 2.1 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 AAAP01003832.1_22 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 AAAP01003832.1_22 - 0.17 11.9 0.0 0.34 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 AAAP01003832.1_22 - 0.19 10.9 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA_C PF08299.11 AAAP01003832.1_23 - 1.1e-32 111.9 0.9 4e-32 110.1 0.5 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein helix-turn-helix Bac_DnaA PF00308.18 AAAP01003832.1_23 - 5.9e-13 49.2 0.5 1.7e-12 47.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein HIGH_NTase1_ass PF16581.5 AAAP01003832.1_23 - 0.00055 20.0 0.2 0.00082 19.4 0.2 1.2 1 0 0 1 1 1 1 Cytidyltransferase-related C-terminal region DUF3583 PF12126.8 AAAP01003832.1_23 - 0.025 14.1 0.4 0.042 13.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3583) DUF2551 PF10826.8 AAAP01003832.1_23 - 0.044 14.0 0.2 0.63 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) DNA_pol3_beta PF00712.19 AAAP01003832.1_24 - 3.6e-39 133.6 0.0 7.2e-33 113.3 0.0 3.1 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 AAAP01003832.1_24 - 1.9e-37 128.0 0.1 7.1e-33 113.3 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 AAAP01003832.1_24 - 4.5e-35 120.1 0.2 1.1e-33 115.7 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase III beta subunit, C-terminal domain SMC_N PF02463.19 AAAP01003832.1_25 - 7.6e-09 35.3 0.0 1e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003832.1_25 - 1.4e-07 32.2 0.0 1.5e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01003832.1_25 - 2e-07 31.1 0.0 2.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAAP01003832.1_25 - 0.00017 21.4 0.0 0.00022 21.0 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003832.1_25 - 0.00033 20.4 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AAAP01003832.1_25 - 0.011 16.2 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AAAP01003832.1_25 - 0.045 14.1 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 AAAP01003832.1_25 - 0.071 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003832.1_25 - 0.081 12.6 0.1 0.099 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AAAP01003832.1_25 - 0.087 12.4 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01003832.1_25 - 0.092 12.7 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 AAAP01003832.1_25 - 0.25 11.0 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase NTPase_1 PF03266.15 AAAP01003832.1_25 - 0.25 11.2 0.0 0.34 10.8 0.0 1.1 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AAAP01003832.1_25 - 0.26 10.8 0.0 0.56 9.8 0.0 1.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 2Fe-2S_thioredx PF01257.19 AAAP01003833.1_1 - 8e-34 116.6 0.0 1e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_51K PF01512.17 AAAP01003833.1_1 - 5.2e-12 45.9 0.1 8.3e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit DUF3967 PF13152.6 AAAP01003833.1_1 - 0.014 15.1 0.8 0.032 14.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) YvfG PF09628.10 AAAP01003833.1_1 - 0.25 11.7 0.0 0.53 10.7 0.0 1.5 1 0 0 1 1 1 0 YvfG protein Acetyltransf_1 PF00583.25 AAAP01003833.1_2 - 5.7e-07 29.8 0.0 7.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003833.1_2 - 0.00062 20.1 0.0 0.0009 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AAAP01003833.1_2 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_10 PF13673.7 AAAP01003833.1_2 - 0.012 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003833.1_2 - 0.042 13.8 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 AAAP01003833.1_2 - 0.095 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rrf2 PF02082.20 AAAP01003833.1_3 - 3.5e-21 75.3 0.1 5.5e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 AAAP01003833.1_3 - 1.3e-05 25.1 0.3 2.5e-05 24.2 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 AAAP01003833.1_3 - 2.4e-05 23.9 0.3 4e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 AAAP01003833.1_3 - 2.4e-05 24.1 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAAP01003833.1_3 - 0.00013 21.8 0.3 0.00023 21.0 0.1 1.6 2 0 0 2 2 1 1 HTH domain HrcA_DNA-bdg PF03444.15 AAAP01003833.1_3 - 0.00015 21.3 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_27 PF13463.6 AAAP01003833.1_3 - 0.00018 21.9 0.0 0.00056 20.3 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_28 PF13518.6 AAAP01003833.1_3 - 0.0041 17.2 0.1 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 AAAP01003833.1_3 - 0.0052 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 HTH DNA binding domain HTH_47 PF16221.5 AAAP01003833.1_3 - 0.0068 15.9 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 winged helix-turn-helix HTH_IclR PF09339.10 AAAP01003833.1_3 - 0.0073 16.1 0.4 0.015 15.0 0.1 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AAAP01003833.1_3 - 0.011 15.2 0.1 0.03 13.9 0.1 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AAAP01003833.1_3 - 0.021 14.8 0.0 0.068 13.2 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAAP01003833.1_3 - 0.037 13.9 0.2 0.094 12.6 0.1 1.6 2 0 0 2 2 2 0 MarR family Ad_Cy_reg PF16701.5 AAAP01003833.1_3 - 0.071 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain HxlR PF01638.17 AAAP01003833.1_3 - 0.073 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix HTH_23 PF13384.6 AAAP01003833.1_3 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 AAAP01003833.1_3 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Peripla_BP_6 PF13458.6 AAAP01003833.1_4 - 7.5e-62 210.0 10.8 9.5e-62 209.6 10.8 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003833.1_4 - 1.7e-18 66.8 0.0 2.1e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003833.1_4 - 0.00022 20.5 0.0 0.00049 19.3 0.0 1.6 1 1 0 1 1 1 1 Receptor family ligand binding region Glyco_tran_WecB PF03808.13 AAAP01003833.1_4 - 0.0099 15.8 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family LppC PF04348.13 AAAP01003833.1_4 - 0.086 11.6 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein DUF2064 PF09837.9 AAAP01003833.1_4 - 0.093 12.5 0.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Phage_min_cap2 PF06152.11 AAAP01003833.1_4 - 0.26 10.1 0.0 0.49 9.3 0.0 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 Peptidase_M16 PF00675.20 AAAP01003833.1_5 - 1.5e-43 148.4 0.0 4.4e-42 143.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAAP01003833.1_5 - 3.9e-41 141.1 0.0 6.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain GP57 PF17594.2 AAAP01003833.1_5 - 0.017 14.8 0.1 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 Thr_synth_N PF14821.6 AAAP01003833.1_6 - 1.7e-28 98.6 0.0 5.2e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 AAAP01003833.1_6 - 1.3e-23 83.8 0.6 1.9e-22 80.1 0.6 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RELT PF12606.8 AAAP01003833.1_6 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Ntox44 PF15607.6 AAAP01003833.1_6 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 44 HATPase_c PF02518.26 AAAP01003833.1_7 - 1.3e-22 80.4 0.0 2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003833.1_7 - 2.1e-10 40.5 0.0 5.7e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AAAP01003833.1_7 - 2.9e-09 37.1 0.0 6.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003833.1_7 - 2e-06 27.7 0.0 7.9e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003833.1_7 - 0.00041 20.6 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AAAP01003833.1_7 - 0.0016 18.6 0.0 0.0069 16.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 AAAP01003833.1_7 - 0.007 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold Phasin_2 PF09361.10 AAAP01003833.1_8 - 2.8e-09 37.1 1.7 3.6e-09 36.8 1.7 1.2 1 0 0 1 1 1 1 Phasin protein DUF3417 PF11897.8 AAAP01003833.1_8 - 0.015 15.8 0.1 0.02 15.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) XPC-binding PF09280.11 AAAP01003833.1_8 - 0.073 12.8 4.3 6.6 6.6 3.3 3.3 1 1 2 3 3 3 0 XPC-binding domain Tsp45I PF06300.12 AAAP01003833.1_8 - 0.14 11.7 0.0 0.16 11.5 0.0 1.0 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme ABC_membrane PF00664.23 AAAP01003833.1_9 - 6.6e-35 121.1 4.6 8.6e-35 120.7 4.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003833.1_9 - 5e-33 114.5 0.0 1.6e-32 112.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AAAP01003833.1_9 - 3.7e-08 33.1 2.6 5.6e-07 29.2 0.9 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAAP01003833.1_9 - 0.0013 19.0 0.1 0.076 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003833.1_9 - 0.003 18.0 0.3 0.0097 16.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 AAAP01003833.1_9 - 0.0063 15.5 0.1 0.02 13.8 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.6 AAAP01003833.1_9 - 0.0081 15.9 0.3 0.035 13.8 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AAAP01003833.1_9 - 0.0097 15.7 0.6 0.13 12.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AAAP01003833.1_9 - 0.014 15.8 0.1 0.51 10.8 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAAP01003833.1_9 - 0.017 14.8 0.1 0.044 13.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAAP01003833.1_9 - 0.027 13.7 0.7 0.076 12.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 AAAP01003833.1_9 - 0.058 13.6 0.0 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003833.1_9 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 AAAP01003833.1_9 - 0.065 12.0 0.4 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 AAAP01003833.1_9 - 0.12 12.7 0.6 2.4 8.5 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TPR_11 PF13414.6 AAAP01003833.1_9 - 0.12 12.1 0.9 0.31 10.8 0.9 1.7 1 0 0 1 1 1 0 TPR repeat AAA_18 PF13238.6 AAAP01003833.1_9 - 0.12 12.9 0.1 0.36 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAAP01003833.1_9 - 0.26 11.8 0.8 0.46 10.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain Pentapeptide PF00805.22 AAAP01003833.1_10 - 3.4e-25 87.3 16.8 3.1e-07 29.9 2.0 4.3 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 AAAP01003833.1_10 - 3e-14 52.9 0.2 0.00072 19.7 0.0 3.4 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 AAAP01003833.1_10 - 1.4e-09 38.0 0.0 5.9e-06 26.4 0.0 2.9 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Response_reg PF00072.24 AAAP01003833.1_10 - 2.9e-07 30.7 0.0 4.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Mito_fiss_reg PF05308.11 AAAP01003833.1_10 - 0.3 11.1 5.1 0.47 10.5 5.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Response_reg PF00072.24 AAAP01003833.1_11 - 1.5e-22 79.9 0.0 1.7e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DsbC PF11412.8 AAAP01003833.1_12 - 4.9e-19 68.6 0.0 7.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 AAAP01003833.1_12 - 7.6e-12 45.2 0.0 1.4e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 AAAP01003833.1_12 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin PF00085.20 AAAP01003833.1_12 - 0.22 11.5 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Sulfate_transp PF00916.20 AAAP01003833.1_13 - 3.4e-41 141.3 23.6 5.7e-41 140.5 23.6 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 AAAP01003833.1_13 - 8.5e-16 57.8 0.1 2.8e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.21 AAAP01003833.1_13 - 5.9e-11 42.0 0.0 1.9e-09 37.2 0.0 2.3 1 1 0 2 2 2 1 STAS domain STAS_2 PF13466.6 AAAP01003833.1_13 - 0.015 15.6 0.0 0.087 13.2 0.0 2.4 1 0 0 1 1 1 0 STAS domain NrfD PF03916.14 AAAP01003833.1_15 - 2.1e-40 139.3 24.2 4.6e-40 138.2 24.2 1.5 1 1 0 1 1 1 1 Polysulphide reductase, NrfD Fer4_11 PF13247.6 AAAP01003833.1_16 - 7.2e-19 67.8 18.6 4.5e-18 65.2 15.2 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003833.1_16 - 4e-13 49.7 25.8 2.9e-07 31.0 7.6 2.5 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003833.1_16 - 9.4e-11 41.7 24.2 2.1e-07 31.0 6.9 2.5 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003833.1_16 - 6.1e-08 32.7 26.6 0.00024 21.2 8.6 3.0 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003833.1_16 - 6.3e-07 29.2 38.4 4.8e-06 26.4 2.7 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003833.1_16 - 2.1e-06 27.3 8.7 5e-06 26.1 1.4 5.5 6 1 0 6 6 6 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003833.1_16 - 4.1e-06 26.6 33.2 0.00041 20.3 1.5 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003833.1_16 - 9.1e-05 22.5 1.5 9.1e-05 22.5 1.5 3.9 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003833.1_16 - 0.00015 22.4 40.5 0.021 15.8 7.1 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003833.1_16 - 0.00025 21.9 23.1 0.046 14.7 1.9 4.7 4 1 1 5 5 5 3 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AAAP01003833.1_16 - 0.0052 17.3 24.0 0.68 10.5 9.7 3.8 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003833.1_16 - 0.011 16.2 24.9 0.34 11.4 9.4 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Rieske_3 PF18465.1 AAAP01003833.1_16 - 0.019 15.2 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 Rieske 3Fe-4S Fer4_4 PF12800.7 AAAP01003833.1_16 - 0.031 14.8 2.3 0.031 14.8 2.3 4.5 4 1 0 4 4 4 0 4Fe-4S binding domain Fer4_13 PF13370.6 AAAP01003833.1_16 - 0.047 14.2 0.5 0.047 14.2 0.5 4.0 5 0 0 5 5 4 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AAAP01003833.1_16 - 9.6 6.4 24.4 0.36 11.0 7.8 3.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Paired_CXXCH_1 PF09699.10 AAAP01003833.1_17 - 9.1e-05 22.1 12.3 0.00021 21.0 4.2 2.6 2 1 1 3 3 3 2 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C554 PF13435.6 AAAP01003833.1_17 - 0.027 15.4 10.7 0.67 10.9 4.3 2.7 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.6 AAAP01003833.1_17 - 0.034 14.2 10.6 0.083 12.9 4.6 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 AAAP01003833.1_17 - 0.062 13.7 9.2 0.52 10.7 4.3 2.3 1 1 1 2 2 2 0 Class III cytochrome C family Cytochrom_c3_2 PF14537.6 AAAP01003833.1_17 - 0.19 12.2 11.3 12 6.5 10.5 2.5 1 1 0 1 1 1 0 Cytochrome c3 RecR PF02132.15 AAAP01003833.1_17 - 0.55 9.8 4.0 11 5.7 0.1 2.4 2 0 0 2 2 2 0 RecR protein Cytochrome_CBB3 PF13442.6 AAAP01003833.1_17 - 1.2 9.5 12.9 5.9 7.3 0.9 3.1 1 1 2 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III DUF2024 PF09630.10 AAAP01003833.1_17 - 1.5 8.8 4.0 1 9.3 0.6 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2024) DUF3365 PF11845.8 AAAP01003833.1_17 - 2.7 8.3 9.8 8.6 6.7 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) Cytochrome_P460 PF16694.5 AAAP01003833.1_17 - 3.3 8.1 12.9 3.8 7.9 0.6 3.1 1 1 2 3 3 3 0 Cytochrome P460 Pyr_redox_2 PF07992.14 AAAP01003833.1_18 - 1.5e-24 86.8 0.1 5.9e-24 84.8 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 AAAP01003833.1_18 - 3.5e-15 55.7 13.2 3.7e-12 46.0 0.0 3.3 2 1 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 AAAP01003833.1_18 - 3.2e-10 40.1 0.1 1.1e-09 38.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAAP01003833.1_18 - 3.3e-09 37.2 4.7 0.0009 19.8 0.1 3.7 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.6 AAAP01003833.1_18 - 8.8e-09 35.4 14.5 6.3e-08 32.6 14.5 2.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003833.1_18 - 3.1e-07 30.9 16.8 3.1e-07 30.9 16.8 3.3 3 1 1 4 4 3 1 4Fe-4S dicluster domain FAD_oxidored PF12831.7 AAAP01003833.1_18 - 4e-07 29.8 0.2 4e-07 29.8 0.2 1.6 2 0 0 2 2 1 1 FAD dependent oxidoreductase DAO PF01266.24 AAAP01003833.1_18 - 8.6e-07 28.9 0.2 2.1e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AAAP01003833.1_18 - 2.3e-06 26.6 0.1 3.9e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AAAP01003833.1_18 - 7.3e-06 25.3 0.4 1.4e-05 24.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_9 PF13187.6 AAAP01003833.1_18 - 8e-06 25.9 14.7 8e-06 25.9 14.7 3.6 2 2 2 4 4 4 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003833.1_18 - 1e-05 25.1 3.9 1e-05 25.1 3.9 4.1 3 1 1 4 4 3 2 4Fe-4S binding domain Pyr_redox_3 PF13738.6 AAAP01003833.1_18 - 3.8e-05 23.1 0.1 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AAAP01003833.1_18 - 3.9e-05 23.0 0.3 9.5e-05 21.7 0.1 1.7 2 0 0 2 2 1 1 Thi4 family GIDA PF01134.22 AAAP01003833.1_18 - 5.3e-05 22.5 0.2 5.3e-05 22.5 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 AAAP01003833.1_18 - 5.5e-05 22.6 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 AAAP01003833.1_18 - 9.6e-05 21.8 0.1 0.00016 21.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Fer4_10 PF13237.6 AAAP01003833.1_18 - 0.00019 21.5 15.8 0.00019 21.5 15.8 3.4 3 1 0 3 3 2 1 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 AAAP01003833.1_18 - 0.00032 20.1 2.0 0.11 11.7 0.0 2.5 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Fer4_2 PF12797.7 AAAP01003833.1_18 - 0.0013 18.7 2.6 0.0013 18.7 2.6 4.5 4 1 0 4 4 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003833.1_18 - 0.0026 17.7 2.5 0.0026 17.7 2.5 4.2 3 1 0 3 3 1 1 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003833.1_18 - 0.0055 17.2 16.8 0.3 11.7 15.8 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003833.1_18 - 0.02 15.4 17.3 0.089 13.2 16.3 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 AAAP01003833.1_18 - 0.021 13.7 0.1 0.05 12.4 0.1 1.6 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 AAAP01003833.1_18 - 0.035 14.1 0.1 0.098 12.6 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AAAP01003833.1_18 - 0.038 13.0 0.1 0.063 12.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 AAAP01003833.1_18 - 0.15 12.5 0.0 0.15 12.5 0.0 2.9 4 0 0 4 4 3 0 Putative NAD(P)-binding Fer4_16 PF13484.6 AAAP01003833.1_18 - 0.33 11.9 22.7 0.085 13.8 3.2 3.4 2 1 3 5 5 4 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AAAP01003833.1_18 - 0.39 10.9 16.9 0.22 11.8 1.7 3.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003833.1_18 - 8.4 7.0 16.3 0.42 11.2 1.6 3.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CCG PF02754.16 AAAP01003833.1_19 - 0.00046 20.4 0.3 0.00089 19.4 0.3 1.5 1 1 0 1 1 1 1 Cysteine-rich domain Helicase_C PF00271.31 AAAP01003834.1_1 - 2e-08 34.5 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MarR PF01047.22 AAAP01003834.1_2 - 4.5e-13 48.9 0.0 6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01003834.1_2 - 2.1e-11 43.5 0.1 3.1e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01003834.1_2 - 4.1e-08 33.6 0.1 6.4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AAAP01003834.1_2 - 8.1e-05 22.4 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 AAAP01003834.1_2 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAAP01003834.1_2 - 0.00015 21.2 0.0 0.00035 20.1 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAAP01003834.1_2 - 0.00036 20.3 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 AAAP01003834.1_2 - 0.00074 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 AAAP01003834.1_2 - 0.0015 18.4 0.0 0.0045 16.9 0.0 1.8 1 1 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AAAP01003834.1_2 - 0.0055 16.5 0.1 0.0099 15.7 0.1 1.5 1 1 0 1 1 1 1 IclR helix-turn-helix domain DUF4423 PF14394.6 AAAP01003834.1_2 - 0.0063 16.2 0.0 0.0072 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_20 PF12840.7 AAAP01003834.1_2 - 0.015 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01003834.1_2 - 0.028 14.4 0.0 0.042 13.8 0.0 1.4 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain TBPIP PF07106.13 AAAP01003834.1_2 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain HTH_1 PF00126.27 AAAP01003834.1_2 - 0.065 13.2 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Rrf2 PF02082.20 AAAP01003834.1_2 - 0.086 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation2 PF16864.5 AAAP01003834.1_2 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain HTH_10 PF04967.12 AAAP01003834.1_2 - 0.13 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain NTP_transferase PF00483.23 AAAP01003834.1_3 - 2.6e-15 56.7 0.0 1e-13 51.5 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003834.1_3 - 2.7e-15 57.1 1.6 3.2e-15 56.8 1.6 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003834.1_3 - 0.0015 18.3 0.1 0.0032 17.2 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_4 PF13704.6 AAAP01003834.1_3 - 0.058 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 APH PF01636.23 AAAP01003834.1_4 - 2.1e-23 83.5 5.7 3.5e-23 82.8 5.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 AAAP01003834.1_4 - 0.00018 20.9 0.8 0.00053 19.4 0.8 1.9 1 1 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase EcKinase PF02958.20 AAAP01003834.1_4 - 0.037 13.3 0.0 0.098 12.0 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase TsaE PF02367.17 AAAP01003834.1_5 - 1.4e-33 115.5 0.0 1.7e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 AAAP01003834.1_5 - 0.0001 22.8 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 AAAP01003834.1_5 - 0.0003 21.3 0.0 0.00034 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AAAP01003834.1_5 - 0.0036 16.8 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 AAAP01003834.1_5 - 0.0049 17.3 0.1 0.0054 17.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003834.1_5 - 0.0073 16.0 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01003834.1_5 - 0.0086 16.4 0.0 0.011 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003834.1_5 - 0.012 15.7 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003834.1_5 - 0.015 15.7 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 AAAP01003834.1_5 - 0.016 15.1 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 AAAP01003834.1_5 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 AAAP01003834.1_5 - 0.017 15.5 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 AAAP01003834.1_5 - 0.017 15.4 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003834.1_5 - 0.018 14.6 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fimbrial_PilY2 PF14481.6 AAAP01003834.1_5 - 0.032 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 T2SSE PF00437.20 AAAP01003834.1_5 - 0.037 13.1 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 AAAP01003834.1_5 - 0.054 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AAAP01003834.1_5 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 AAAP01003834.1_5 - 0.091 11.9 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 AAAP01003834.1_5 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.20 AAAP01003834.1_5 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase CoA_trans PF01144.23 AAAP01003834.1_5 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase RsgA_GTPase PF03193.16 AAAP01003834.1_5 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 AAAP01003834.1_5 - 0.13 12.7 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AAAP01003834.1_5 - 0.16 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AAAP01003834.1_5 - 0.17 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 AAAP01003834.1_5 - 0.21 10.7 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 AAAP01003834.1_5 - 0.22 10.4 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 AAAP01003834.1_5 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Phage_integrase PF00589.22 AAAP01003834.1_6 - 5.7e-34 117.4 0.0 1.1e-33 116.4 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAAP01003834.1_6 - 1.4e-16 60.6 0.3 4.5e-16 58.9 0.1 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAAP01003834.1_6 - 0.0043 17.5 0.0 0.0083 16.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Smr PF01713.21 AAAP01003834.1_6 - 0.066 13.6 0.0 0.19 12.1 0.0 1.9 1 1 0 1 1 1 0 Smr domain Integrase_1 PF12835.7 AAAP01003834.1_6 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 Integrase DUF805 PF05656.14 AAAP01003834.1_7 - 2.7e-34 117.7 2.2 3.1e-34 117.5 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF805) PTR2 PF00854.21 AAAP01003834.1_7 - 0.017 14.0 0.4 0.029 13.2 0.4 1.4 1 1 0 1 1 1 0 POT family DUF2207 PF09972.9 AAAP01003834.1_7 - 0.098 11.4 7.4 0.41 9.4 7.5 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pox_EPC_I2-L1 PF12575.8 AAAP01003834.1_7 - 0.19 12.0 2.5 4.8 7.5 0.0 2.3 2 1 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF1129 PF06570.11 AAAP01003834.1_7 - 0.61 9.5 2.2 0.8 9.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4191 PF13829.6 AAAP01003834.1_7 - 2.3 7.5 3.9 2 7.7 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) PLDc_N PF13396.6 AAAP01003834.1_7 - 6.2 6.8 14.0 0.37 10.8 8.3 2.1 2 1 0 2 2 2 0 Phospholipase_D-nuclease N-terminal DUF484 PF04340.12 AAAP01003834.1_8 - 1.2e-27 97.0 0.2 1.1e-26 93.9 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF484 PriA_C PF18074.1 AAAP01003834.1_9 - 7.8e-19 68.3 0.0 2.1e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Primosomal protein N C-terminal domain PriA_3primeBD PF17764.1 AAAP01003834.1_9 - 4.2e-16 58.6 0.0 8.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) DEAD PF00270.29 AAAP01003834.1_9 - 5.3e-12 45.9 0.0 8.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PriA_CRR PF18319.1 AAAP01003834.1_9 - 6.2e-10 38.9 6.8 6.2e-10 38.9 6.8 2.4 3 0 0 3 3 3 1 PriA DNA helicase Cys-rich region (CRR) domain ResIII PF04851.15 AAAP01003834.1_9 - 5.1e-08 33.1 0.0 9.5e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAAP01003834.1_9 - 1e-06 29.0 0.0 0.0029 17.9 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 AAAP01003834.1_9 - 0.0044 16.7 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain zinc-ribbons_6 PF07191.12 AAAP01003834.1_9 - 0.033 14.2 7.7 0.12 12.4 7.9 1.7 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_12 PF11331.8 AAAP01003834.1_9 - 0.052 13.4 5.5 0.02 14.7 2.8 1.8 1 1 0 1 1 1 0 Probable zinc-ribbon domain HTH_Tnp_Tc5 PF03221.16 AAAP01003834.1_9 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain GHMP_kinases_N PF00288.26 AAAP01003834.1_10 - 6e-08 32.8 0.9 6e-08 32.8 0.9 2.0 2 1 1 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAAP01003834.1_10 - 1.2e-05 25.6 0.1 2.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal E1-N PF14463.6 AAAP01003834.1_10 - 0.007 16.2 2.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 E1 N-terminal domain TPR_2 PF07719.17 AAAP01003834.1_11 - 1.5e-27 93.5 34.3 8.3e-05 22.4 0.1 11.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003834.1_11 - 3.7e-26 91.5 53.0 2.5e-08 34.5 0.3 10.0 6 3 3 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003834.1_11 - 1e-25 90.0 29.3 0.00011 22.6 0.0 8.9 6 2 1 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003834.1_11 - 1.4e-21 75.3 56.2 3.1e-05 24.4 0.1 13.2 3 3 11 14 14 14 7 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003834.1_11 - 2.6e-18 65.4 21.7 4.5e-06 26.2 0.0 10.2 9 2 2 11 11 10 4 TPR repeat TPR_1 PF00515.28 AAAP01003834.1_11 - 9.5e-16 56.9 16.7 0.00013 21.6 0.0 9.1 11 0 0 11 11 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003834.1_11 - 6.4e-13 48.8 32.2 0.0018 18.5 0.0 10.1 7 3 3 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003834.1_11 - 1.1e-12 47.1 14.7 0.0011 19.0 0.0 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003834.1_11 - 9e-12 44.5 8.9 0.11 12.9 0.0 8.2 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_21 PF09976.9 AAAP01003834.1_11 - 1.8e-11 44.1 17.6 2.2e-06 27.5 2.8 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 AAAP01003834.1_11 - 5.1e-11 42.6 25.1 1.2e-05 25.3 0.0 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003834.1_11 - 2e-10 40.6 37.3 0.018 15.6 0.1 10.1 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003834.1_11 - 3.5e-10 39.6 22.5 5.8e-07 29.0 1.3 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003834.1_11 - 4.2e-09 35.8 20.0 0.0095 15.9 0.0 8.2 8 1 1 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003834.1_11 - 1.1e-05 25.5 3.1 1.3 9.3 0.1 4.4 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 AAAP01003834.1_11 - 0.0059 15.6 1.3 2.1 7.2 0.1 2.9 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 AAAP01003834.1_11 - 0.011 15.8 0.0 1.4 9.1 0.0 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Cohesin_load PF10345.9 AAAP01003834.1_11 - 0.012 14.1 0.1 1.2 7.4 0.0 2.5 3 0 0 3 3 3 0 Cohesin loading factor TPR_10 PF13374.6 AAAP01003834.1_11 - 0.013 15.3 0.1 0.013 15.3 0.1 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat PPR PF01535.20 AAAP01003834.1_11 - 0.015 15.5 1.2 23 5.5 0.0 4.8 4 0 0 4 4 4 0 PPR repeat HrpB1_HrpK PF09613.10 AAAP01003834.1_11 - 0.027 14.1 5.4 0.42 10.2 0.6 3.6 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 AAAP01003834.1_11 - 0.032 14.5 12.6 0.62 10.4 0.2 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003834.1_11 - 0.062 14.0 41.0 0.14 12.9 0.5 9.8 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.17 AAAP01003834.1_11 - 0.093 13.2 0.1 0.093 13.2 0.1 4.4 3 1 1 4 4 3 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 AAAP01003834.1_11 - 0.2 11.7 2.9 32 4.6 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 AAAP01003834.1_11 - 1.1 10.0 10.8 16 6.3 0.7 5.6 4 2 1 5 5 5 0 Sel1 repeat ETF_QO PF05187.13 AAAP01003834.1_12 - 1.7e-51 172.7 0.6 2.7e-51 172.0 0.1 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Thi4 PF01946.17 AAAP01003834.1_12 - 1.3e-09 37.7 0.1 1.3e-07 31.1 0.1 2.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 AAAP01003834.1_12 - 1.4e-08 34.7 1.3 6.1e-05 22.8 0.4 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003834.1_12 - 1.5e-07 31.6 0.0 1.5e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AAAP01003834.1_12 - 2.4e-07 30.2 0.7 2.7e-06 26.8 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AAAP01003834.1_12 - 8.1e-06 24.8 0.1 1.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 AAAP01003834.1_12 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003834.1_12 - 0.00013 21.4 0.3 0.0002 20.7 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AAAP01003834.1_12 - 0.00018 20.7 2.1 0.00026 20.1 0.3 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 AAAP01003834.1_12 - 0.0003 19.8 0.2 0.024 13.5 0.1 2.4 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 AAAP01003834.1_12 - 0.00051 20.6 0.1 0.16 12.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAAP01003834.1_12 - 0.0035 16.7 0.6 0.0061 16.0 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AAAP01003834.1_12 - 0.0059 15.8 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 AAAP01003834.1_12 - 0.01 15.2 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 AAAP01003834.1_12 - 0.012 15.6 0.1 0.033 14.2 0.1 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AAAP01003834.1_12 - 0.022 14.0 2.7 0.025 13.9 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 AAAP01003834.1_12 - 0.027 13.0 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Fer4_7 PF12838.7 AAAP01003834.1_12 - 0.03 14.9 0.7 0.061 13.9 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 AAAP01003834.1_12 - 0.081 12.0 0.4 0.15 11.1 0.3 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A UDG PF03167.19 AAAP01003834.1_13 - 3.6e-46 157.0 0.0 5.2e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RskA PF10099.9 AAAP01003834.1_13 - 0.13 12.6 12.3 0.63 10.3 0.2 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Cadherin_5 PF17892.1 AAAP01003834.1_14 - 1.9e-63 210.5 44.9 7.3e-29 99.6 4.1 5.9 5 0 0 5 5 5 4 Cadherin-like domain Big_9 PF17963.1 AAAP01003834.1_14 - 3.2e-40 136.8 59.4 4.6e-18 65.8 8.2 12.2 8 3 2 10 10 10 4 Bacterial Ig domain HemolysinCabind PF00353.19 AAAP01003834.1_14 - 1.2e-35 121.0 130.8 1.1e-09 38.1 14.2 10.5 9 3 3 12 12 12 8 RTX calcium-binding nonapeptide repeat (4 copies) Cadherin_4 PF17803.1 AAAP01003834.1_14 - 1.2e-20 73.9 38.4 2.3e-10 41.0 7.0 11.9 7 4 1 8 8 8 4 Bacterial cadherin-like domain DUF3446 PF11928.8 AAAP01003834.1_15 - 0.066 13.5 4.9 0.084 13.2 4.9 1.1 1 0 0 1 1 1 0 Early growth response N-terminal domain HTH_28 PF13518.6 AAAP01003835.1_1 - 7.4e-10 38.8 0.0 2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AAAP01003835.1_1 - 1.1e-06 28.6 0.1 2.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01003835.1_1 - 0.00076 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 AAAP01003835.1_1 - 0.052 14.2 1.7 0.14 12.8 0.1 2.7 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAAP01003835.1_1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Response_reg PF00072.24 AAAP01003835.1_2 - 6.3e-18 65.0 0.0 8.3e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003835.1_2 - 2.4e-14 53.1 0.0 5.3e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AAAP01003835.1_3 - 7.5e-26 90.8 0.0 1.3e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003835.1_3 - 2.6e-10 40.2 0.6 6.5e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAAP01003835.1_3 - 3.1e-08 33.8 0.1 6.2e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_5 PF14501.6 AAAP01003835.1_3 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AAAP01003835.1_3 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain GGDEF_2 PF17853.1 AAAP01003835.1_3 - 0.12 12.7 0.9 0.78 10.0 0.1 2.4 2 0 0 2 2 2 0 GGDEF-like domain DUF1987 PF09345.10 AAAP01003835.1_5 - 1.6e-44 150.4 0.0 1.8e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1987) HPTransfase PF10090.9 AAAP01003835.1_5 - 0.0061 16.4 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain HATPase_c PF02518.26 AAAP01003835.1_6 - 2.9e-20 72.9 0.0 6.3e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003835.1_6 - 5.2e-05 23.2 0.7 0.00028 20.9 0.0 2.4 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ERM PF00769.19 AAAP01003835.1_6 - 0.0041 17.0 1.7 0.0062 16.4 1.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MRFAP1 PF15155.6 AAAP01003835.1_6 - 0.05 14.1 2.0 0.098 13.2 2.0 1.4 1 0 0 1 1 1 0 MORF4 family-associated protein1 HD_3 PF13023.6 AAAP01003835.1_6 - 0.067 13.1 0.5 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 HD domain DUF4527 PF15030.6 AAAP01003835.1_6 - 0.24 10.8 3.0 0.38 10.1 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4527) HAUS-augmin3 PF14932.6 AAAP01003835.1_6 - 0.25 10.9 3.6 0.43 10.1 3.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TPR_MLP1_2 PF07926.12 AAAP01003835.1_6 - 0.3 11.1 7.3 0.5 10.4 7.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 AAAP01003835.1_6 - 0.43 10.8 2.4 0.86 9.9 2.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF883 PF05957.13 AAAP01003835.1_6 - 1.1 9.9 9.0 4.5 7.9 0.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.12 AAAP01003835.1_6 - 1.1 7.7 5.9 1.8 7.0 5.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DegS PF05384.11 AAAP01003835.1_6 - 1.4 8.4 6.1 1.1 8.7 0.4 2.7 2 1 1 3 3 3 0 Sensor protein DegS Cortex-I_coil PF09304.10 AAAP01003835.1_6 - 1.7 8.9 6.5 17 5.7 3.8 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil HisKA_3 PF07730.13 AAAP01003835.1_6 - 2 9.0 8.6 0.35 11.4 0.5 2.8 2 1 1 3 3 3 0 Histidine kinase APG6_N PF17675.1 AAAP01003835.1_6 - 3.3 8.3 8.4 4.9 7.7 6.4 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region GGDEF PF00990.21 AAAP01003835.1_7 - 3e-44 150.6 0.0 5.7e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AAAP01003835.1_7 - 2.3e-11 43.9 0.0 1.3e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold Response_reg PF00072.24 AAAP01003835.1_7 - 5.7e-08 32.9 0.1 1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AAAP01003835.1_7 - 5.2e-06 26.3 0.0 2.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AAAP01003835.1_7 - 1.9e-05 24.6 0.0 4.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003835.1_7 - 0.019 15.2 0.0 0.068 13.4 0.0 2.0 2 1 0 2 2 2 0 PAS domain PAS_7 PF12860.7 AAAP01003835.1_7 - 0.024 14.8 0.0 7.6 6.7 0.0 2.4 2 0 0 2 2 2 0 PAS fold SBP_bac_3 PF00497.20 AAAP01003835.1_8 - 3.3e-13 49.6 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Sel_put PF04328.13 AAAP01003835.1_8 - 0.15 12.1 0.1 0.39 10.8 0.1 1.7 1 0 0 1 1 1 0 Selenoprotein, putative Abhydrolase_6 PF12697.7 AAAP01003835.1_9 - 1.3e-20 75.0 5.5 1.6e-20 74.7 5.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003835.1_9 - 4.4e-15 56.0 0.0 4.8e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01003835.1_9 - 2.2e-06 27.1 0.0 1.3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PCP_red PF08369.10 AAAP01003835.1_9 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Hpt PF01627.23 AAAP01003835.1_10 - 0.00011 22.4 0.1 0.00086 19.5 0.1 2.1 1 1 0 1 1 1 1 Hpt domain Response_reg PF00072.24 AAAP01003835.1_10 - 0.00064 19.9 0.0 0.0025 18.0 0.0 1.9 2 1 1 3 3 3 1 Response regulator receiver domain Vps51 PF08700.11 AAAP01003835.1_10 - 0.022 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Vps51/Vps67 EspB_PE PF18625.1 AAAP01003835.1_10 - 0.11 13.0 0.1 0.26 11.8 0.1 1.6 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Rrf2 PF02082.20 AAAP01003835.1_11 - 3.8e-23 81.6 0.1 5.4e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01003835.1_11 - 4.8e-06 26.4 0.0 9.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAAP01003835.1_11 - 8.6e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.6 AAAP01003835.1_11 - 0.0018 18.7 0.1 0.003 18.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AAAP01003835.1_11 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 AAAP01003835.1_11 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 AAAP01003835.1_11 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAAP01003835.1_11 - 0.0053 16.7 0.1 0.011 15.7 0.0 1.5 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 AAAP01003835.1_11 - 0.0064 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 AAAP01003835.1_11 - 0.007 16.3 0.1 0.021 14.8 0.1 1.8 2 0 0 2 2 2 1 HTH domain HTH_6 PF01418.17 AAAP01003835.1_11 - 0.0071 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family Fe_dep_repress PF01325.19 AAAP01003835.1_11 - 0.0083 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain PuR_N PF09182.10 AAAP01003835.1_11 - 0.01 15.8 0.1 0.055 13.4 0.1 2.0 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal HTH_AraC PF00165.23 AAAP01003835.1_11 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Rio2_N PF09202.11 AAAP01003835.1_11 - 0.03 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Rio2, N-terminal HTH_28 PF13518.6 AAAP01003835.1_11 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003835.1_11 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AAAP01003835.1_11 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 HTH DNA binding domain HTH_46 PF15977.5 AAAP01003835.1_11 - 0.075 13.1 0.1 0.18 11.8 0.1 1.7 1 1 1 2 2 2 0 Winged helix-turn-helix DNA binding RQC PF09382.10 AAAP01003835.1_11 - 0.083 12.7 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 RQC domain HTH_17 PF12728.7 AAAP01003835.1_11 - 0.085 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003835.1_11 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain SgrR_N PF12793.7 AAAP01003835.1_11 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term HTH_36 PF13730.6 AAAP01003835.1_11 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HATPase_c PF02518.26 AAAP01003835.1_12 - 6.7e-27 94.2 0.0 1.3e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003835.1_12 - 2.8e-25 88.7 0.0 1e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003835.1_12 - 4.4e-16 58.7 0.2 4.4e-16 58.7 0.2 3.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003835.1_12 - 1.8e-05 25.1 9.2 0.00038 20.8 0.3 4.3 4 0 0 4 4 4 1 HAMP domain Phage_sheath_1 PF04984.14 AAAP01003835.1_12 - 0.1 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain FAM184 PF15665.5 AAAP01003835.1_12 - 1.5 8.6 8.4 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B ECH_1 PF00378.20 AAAP01003835.1_14 - 4.6e-46 157.2 0.0 5.6e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003835.1_14 - 1.8e-24 86.9 0.0 2.2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3599 PF12206.8 AAAP01003835.1_14 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) Pribosyltran PF00156.27 AAAP01003835.1_15 - 9.2e-09 35.0 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PQ-loop PF04193.14 AAAP01003835.1_16 - 1.8e-09 37.2 0.7 2.7e-09 36.7 0.7 1.2 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 AAAP01003835.1_16 - 2.1e-05 24.5 0.7 2.7e-05 24.1 0.7 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange DUF3040 PF11239.8 AAAP01003835.1_16 - 0.046 14.0 1.9 0.066 13.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Imp-YgjV PF10688.9 AAAP01003835.1_16 - 0.077 12.8 5.0 0.25 11.2 5.0 1.8 1 1 0 1 1 1 0 Bacterial inner membrane protein LrgA PF03788.14 AAAP01003835.1_17 - 4.3e-24 84.3 8.2 5.2e-24 84.0 8.2 1.1 1 0 0 1 1 1 1 LrgA family EmrE PF13536.6 AAAP01003835.1_17 - 0.038 13.6 2.4 0.073 12.7 1.8 1.6 1 1 1 2 2 2 0 Putative multidrug resistance efflux transporter LrgB PF04172.16 AAAP01003835.1_18 - 1.2e-79 266.9 18.4 1.3e-79 266.6 18.4 1.0 1 0 0 1 1 1 1 LrgB-like family DUF4148 PF13663.6 AAAP01003835.1_19 - 7 6.9 11.5 4.9 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Gate PF07670.14 AAAP01003835.1_20 - 7.2e-10 39.1 14.1 3.2e-09 37.0 0.5 3.4 4 0 0 4 4 4 2 Nucleoside recognition TerC PF03741.16 AAAP01003835.1_21 - 8.7e-21 74.4 0.1 9.6e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein TerC family Crp PF00325.20 AAAP01003835.1_21 - 0.098 12.3 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Mntp PF02659.15 AAAP01003835.1_21 - 0.22 11.3 5.7 0.27 11.0 2.5 2.0 1 1 1 2 2 2 0 Putative manganese efflux pump NUDIX PF00293.28 AAAP01003835.1_22 - 2.7e-12 46.9 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CopD PF05425.13 AAAP01003835.1_23 - 1.1e-05 25.8 2.1 1.1e-05 25.8 2.1 2.1 2 0 0 2 2 2 1 Copper resistance protein D DUF4149 PF13664.6 AAAP01003835.1_23 - 0.00032 21.0 7.0 0.00032 21.0 7.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2214 PF09980.9 AAAP01003835.1_23 - 0.037 13.8 7.4 0.11 12.3 7.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2214) AAA_31 PF13614.6 AAAP01003835.1_24 - 1.2e-19 70.9 0.2 2.4e-11 43.9 0.1 2.2 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 AAAP01003835.1_24 - 2.1e-16 60.2 0.0 3.2e-16 59.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AAAP01003835.1_24 - 4.3e-15 55.7 0.5 5.3e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 ATPase MipZ ParA PF10609.9 AAAP01003835.1_24 - 1.5e-09 37.7 5.2 2.8e-09 36.8 0.3 2.6 1 1 1 2 2 2 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 AAAP01003835.1_24 - 5.6e-08 32.4 0.3 4.1e-07 29.5 0.3 2.0 1 1 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 AAAP01003835.1_24 - 1.2e-07 31.4 0.2 0.0022 17.5 0.1 2.2 1 1 1 2 2 2 2 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAAP01003835.1_24 - 9.3e-06 25.0 0.1 2.6e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 AAAP01003835.1_24 - 0.0037 16.3 0.4 0.0097 14.9 0.2 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 AAAP01003835.1_24 - 0.02 14.5 1.8 0.026 14.1 0.3 2.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 AAAP01003835.1_24 - 0.027 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AAAP01003835.1_24 - 0.053 13.4 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 AAAP01003835.1_24 - 0.11 12.1 0.6 0.34 10.5 0.6 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3649 PF12365.8 AAAP01003835.1_25 - 0.013 15.2 1.9 0.013 15.2 1.9 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) Methyltransf_23 PF13489.6 AAAP01003835.1_26 - 3.2e-15 56.4 0.0 4.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003835.1_26 - 1.9e-09 38.1 0.1 2.8e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003835.1_26 - 6.8e-09 36.4 0.0 1.2e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003835.1_26 - 1.6e-08 35.1 0.1 2.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01003835.1_26 - 0.00093 18.6 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF3419 PF11899.8 AAAP01003835.1_26 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) CheR PF01739.18 AAAP01003835.1_26 - 0.0096 15.4 0.0 0.036 13.5 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.6 AAAP01003835.1_26 - 0.018 14.8 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 AAAP01003835.1_26 - 0.036 15.1 0.1 0.058 14.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 AAAP01003835.1_26 - 0.049 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 AAAP01003835.1_26 - 0.077 13.1 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pox_MCEL PF03291.16 AAAP01003835.1_26 - 0.081 12.0 0.0 0.68 9.0 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme Methyltransf_2 PF00891.18 AAAP01003835.1_26 - 0.15 11.3 0.1 0.29 10.4 0.1 1.4 1 1 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 AAAP01003835.1_26 - 0.18 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ribosomal_L37ae PF01780.19 AAAP01003835.1_26 - 0.23 11.6 0.2 0.46 10.6 0.0 1.6 2 0 0 2 2 1 0 Ribosomal L37ae protein family Fer2_2 PF01799.20 AAAP01003835.1_27 - 9.5e-28 96.0 0.2 9.5e-28 96.0 0.2 1.5 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003835.1_27 - 5e-06 26.4 0.2 5e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01003835.1_27 - 1e-05 25.5 0.9 1e-05 25.5 0.9 1.7 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAAP01003835.1_27 - 0.00047 20.2 0.9 0.0066 16.5 0.4 2.8 4 0 0 4 4 4 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AAAP01003835.1_27 - 0.043 13.6 4.3 0.043 13.6 4.3 1.8 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ald_Xan_dh_C2 PF02738.18 AAAP01003835.1_28 - 7.4e-70 235.9 0.0 1.6e-25 89.6 0.0 3.9 3 1 0 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01003835.1_28 - 0.0017 18.7 0.0 0.12 12.8 0.0 2.6 1 1 1 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD-SLDH PF12318.8 AAAP01003835.1_28 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase PALP PF00291.25 AAAP01003835.1_29 - 1.8e-56 191.7 0.1 2.6e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 AAAP01003835.1_30 - 9.6e-05 22.9 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain S-methyl_trans PF02574.16 AAAP01003836.1_2 - 1e-51 176.4 0.0 1.9e-51 175.5 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.17 AAAP01003836.1_2 - 6.8e-47 160.2 0.0 1e-46 159.7 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.22 AAAP01003836.1_2 - 8.5e-42 143.5 0.2 1.5e-41 142.7 0.2 1.4 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 AAAP01003836.1_2 - 6.9e-26 90.5 0.1 2.7e-25 88.6 0.1 2.1 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 AAAP01003836.1_2 - 1.9e-20 73.1 0.6 5.8e-20 71.5 0.6 1.9 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.16 AAAP01003836.1_2 - 0.033 12.9 0.1 0.065 11.9 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit MTHFR PF02219.17 AAAP01003836.1_3 - 1.1e-94 317.0 0.0 1.3e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_11 PF08241.12 AAAP01003836.1_4 - 8.5e-24 84.0 0.0 2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003836.1_4 - 5.8e-20 71.6 0.0 1.1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003836.1_4 - 4.2e-19 69.0 0.0 1e-18 67.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HTH_5 PF01022.20 AAAP01003836.1_4 - 2.3e-15 56.2 0.5 4.2e-15 55.3 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Methyltransf_12 PF08242.12 AAAP01003836.1_4 - 5.4e-14 52.7 0.0 1.6e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003836.1_4 - 1.5e-13 51.0 0.0 2.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003836.1_4 - 5.8e-12 45.4 0.0 8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MarR_2 PF12802.7 AAAP01003836.1_4 - 2.5e-09 36.9 0.5 1.8e-08 34.1 0.2 2.6 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAAP01003836.1_4 - 6.3e-09 35.8 0.8 6.3e-09 35.8 0.8 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Methyltransf_2 PF00891.18 AAAP01003836.1_4 - 1.2e-07 31.3 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_24 PF13412.6 AAAP01003836.1_4 - 2.8e-06 26.8 0.2 7.7e-06 25.4 0.1 1.9 2 0 0 2 2 1 1 Winged helix-turn-helix DNA-binding MTS PF05175.14 AAAP01003836.1_4 - 1.8e-05 24.4 0.1 3.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TrmB PF01978.19 AAAP01003836.1_4 - 0.00021 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PCMT PF01135.19 AAAP01003836.1_4 - 0.00031 20.6 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MarR PF01047.22 AAAP01003836.1_4 - 0.0014 18.5 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 MarR family NodS PF05401.11 AAAP01003836.1_4 - 0.0017 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 AAAP01003836.1_4 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase HTH_IclR PF09339.10 AAAP01003836.1_4 - 0.0058 16.4 4.3 0.02 14.7 0.6 2.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_29 PF13551.6 AAAP01003836.1_4 - 0.0092 16.0 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 AAAP01003836.1_4 - 0.0096 15.7 1.2 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain DREV PF05219.12 AAAP01003836.1_4 - 0.015 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase UPF0020 PF01170.18 AAAP01003836.1_4 - 0.029 14.1 0.0 0.08 12.6 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 HTH_27 PF13463.6 AAAP01003836.1_4 - 0.035 14.6 0.0 0.093 13.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain AbiEi_4 PF13338.6 AAAP01003836.1_4 - 0.071 13.3 0.0 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin HTH_Crp_2 PF13545.6 AAAP01003836.1_4 - 0.078 13.0 4.1 0.19 11.8 0.1 2.8 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_37 PF13744.6 AAAP01003836.1_4 - 0.15 12.0 1.7 0.58 10.1 0.1 2.7 4 0 0 4 4 3 0 Helix-turn-helix domain Lactamase_B_3 PF13483.6 AAAP01003836.1_4 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Methyltransf_32 PF13679.6 AAAP01003836.1_4 - 0.2 11.6 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MlaA PF04333.13 AAAP01003836.1_5 - 3.2e-72 242.4 0.0 3.7e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 MlaA lipoprotein MlaC PF05494.12 AAAP01003836.1_6 - 5.5e-39 133.6 0.2 6.8e-39 133.3 0.2 1.1 1 0 0 1 1 1 1 MlaC protein DUF4139 PF13598.6 AAAP01003836.1_7 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 AAAP01003836.1_7 - 0.042 14.3 0.2 0.2 12.1 0.0 2.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Mtf2_C PF14061.6 AAAP01003836.1_7 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Iso_dh PF00180.20 AAAP01003836.1_8 - 2.1e-131 438.2 0.0 2.4e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aconitase_C PF00694.19 AAAP01003836.1_9 - 5.6e-40 136.7 0.0 8.6e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 AAAP01003836.1_10 - 1.9e-60 205.2 0.1 2.1e-60 205.1 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AAAP01003836.1_10 - 0.00032 19.5 0.1 0.00099 17.9 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF521) DUF1471 PF07338.13 AAAP01003836.1_10 - 0.079 12.9 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Aconitase PF00330.20 AAAP01003836.1_11 - 2.8e-84 283.7 1.1 3.4e-84 283.5 1.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Ribosomal_L19 PF01245.20 AAAP01003836.1_12 - 7.9e-50 167.5 1.1 9.8e-50 167.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 tRNA_m1G_MT PF01746.21 AAAP01003836.1_13 - 1.5e-49 168.3 0.0 1.8e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RimM PF01782.18 AAAP01003836.1_14 - 2.2e-21 75.8 0.4 3.4e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AAAP01003836.1_14 - 1.6e-08 34.5 0.7 1.6e-08 34.5 0.7 1.7 2 0 0 2 2 2 1 PRC-barrel domain Ribosomal_S16 PF00886.19 AAAP01003836.1_15 - 2.7e-27 94.6 0.1 4.5e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 SRP54 PF00448.22 AAAP01003836.1_16 - 4.3e-70 235.3 1.2 8e-70 234.5 1.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AAAP01003836.1_16 - 4e-34 117.2 3.3 1.1e-33 115.7 3.3 1.8 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 AAAP01003836.1_16 - 2.7e-21 75.6 0.3 8.9e-21 73.9 0.3 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AAAP01003836.1_16 - 7.8e-08 32.4 0.8 2.9e-07 30.6 0.2 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AAAP01003836.1_16 - 2.1e-06 27.2 0.1 5.2e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.6 AAAP01003836.1_16 - 1.8e-05 24.7 2.4 0.00063 19.7 0.5 3.0 2 1 1 3 3 3 1 AAA domain ArsA_ATPase PF02374.15 AAAP01003836.1_16 - 0.00017 20.9 8.9 0.00022 20.5 0.5 3.4 2 2 1 4 4 4 1 Anion-transporting ATPase AAA_33 PF13671.6 AAAP01003836.1_16 - 0.00023 21.3 0.9 0.0013 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 AAAP01003836.1_16 - 0.0013 18.3 0.4 0.0031 17.0 0.3 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase APS_kinase PF01583.20 AAAP01003836.1_16 - 0.0045 16.9 0.2 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase 6PF2K PF01591.18 AAAP01003836.1_16 - 0.016 14.5 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.12 AAAP01003836.1_16 - 0.024 14.6 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 AAAP01003836.1_16 - 0.036 14.1 0.3 0.099 12.6 0.1 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AAAP01003836.1_16 - 0.039 13.5 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AAAP01003836.1_16 - 0.044 13.5 0.2 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 AAAP01003836.1_16 - 0.079 12.4 0.1 0.079 12.4 0.1 2.3 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 AAAP01003836.1_16 - 0.1 13.1 0.5 0.45 11.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA PF00004.29 AAAP01003836.1_16 - 0.13 12.7 0.8 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 AAAP01003836.1_16 - 1.5 8.5 4.6 0.26 10.9 0.4 1.8 2 0 0 2 2 2 0 Thymidylate kinase DUF2508 PF10704.9 AAAP01003836.1_16 - 2.7 8.2 5.2 44 4.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DEAD PF00270.29 AAAP01003836.1_17 - 1.2e-42 145.6 0.0 2.3e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAAP01003836.1_17 - 2.9e-25 88.8 0.0 1.3e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AAAP01003836.1_17 - 2.1e-16 59.6 0.1 4.1e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 AAAP01003836.1_17 - 0.00043 20.3 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AAAP01003836.1_17 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 AAAP01003836.1_17 - 0.24 11.7 1.1 3.9 7.7 1.1 2.5 1 1 0 1 1 1 0 AAA domain OEP PF02321.18 AAAP01003836.1_18 - 2.8e-21 76.2 9.4 1.4e-10 41.3 0.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein ABC_membrane PF00664.23 AAAP01003836.1_19 - 8.6e-19 68.2 1.4 1.1e-18 67.8 1.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003836.1_20 - 5.3e-18 65.8 0.0 7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01003836.1_20 - 3.4e-06 26.7 0.0 3.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain HlyD_3 PF13437.6 AAAP01003836.1_21 - 1.1e-16 61.4 0.2 6.8e-14 52.5 0.1 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003836.1_21 - 7.7e-11 41.6 3.3 1.1e-08 34.5 0.0 2.5 1 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAAP01003836.1_21 - 5.9e-08 32.5 0.0 8.5e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003836.1_21 - 3.5e-05 23.5 0.6 0.0038 17.0 0.1 2.9 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003836.1_21 - 0.0023 17.7 2.1 0.1 12.5 0.1 3.1 2 1 0 2 2 2 1 Biotin-requiring enzyme Csm1_N PF18504.1 AAAP01003836.1_21 - 0.04 14.3 0.2 0.04 14.3 0.2 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 AAAP01003836.1_21 - 0.36 11.1 5.4 0.95 9.8 1.2 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF724 PF05266.14 AAAP01003836.1_21 - 0.98 9.2 3.9 1.7 8.4 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) MscS_porin PF12795.7 AAAP01003836.1_21 - 4.4 6.8 8.5 0.15 11.6 0.7 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FecR PF04773.13 AAAP01003836.1_22 - 1.8e-06 28.5 0.1 3.7e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 FecR protein HAD_2 PF13419.6 AAAP01003837.1_1 - 1e-27 97.4 0.0 1.2e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003837.1_1 - 8.8e-15 55.6 0.1 4.5e-14 53.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003837.1_1 - 2.8e-07 31.1 0.0 3.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003837.1_1 - 0.0036 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Cupredoxin_1 PF13473.6 AAAP01003837.1_2 - 4.5e-06 26.7 0.0 4.2e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Cupredoxin-like domain Cupin_5 PF06172.11 AAAP01003837.1_3 - 5.2e-50 169.3 0.0 5.9e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) GST_N_3 PF13417.6 AAAP01003837.1_4 - 5.6e-18 65.1 0.0 1.6e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003837.1_4 - 3.7e-15 56.0 0.0 7.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01003837.1_4 - 3.6e-09 36.8 0.0 1.2e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003837.1_4 - 5.8e-05 23.0 1.4 0.00012 22.0 1.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RskA PF10099.9 AAAP01003837.1_5 - 0.0078 16.5 0.0 0.0089 16.3 0.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PEPCK_GTP PF00821.18 AAAP01003837.1_6 - 4.9e-167 555.2 0.2 6.7e-167 554.8 0.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 AAAP01003837.1_6 - 2.8e-104 347.5 0.0 3.6e-104 347.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Pyrid_oxidase_2 PF13883.6 AAAP01003837.1_7 - 3.6e-09 36.8 0.0 5.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 AAAP01003837.1_7 - 4e-09 36.5 0.1 1.1e-08 35.2 0.1 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Draxin PF15550.6 AAAP01003837.1_8 - 0.015 15.2 1.0 0.016 15.1 1.0 1.1 1 0 0 1 1 1 0 Draxin HTH_3 PF01381.22 AAAP01003837.1_9 - 4.2e-15 55.5 0.1 1e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003837.1_9 - 1.6e-11 44.4 0.2 1.9e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003837.1_9 - 1.1e-09 38.1 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AAAP01003837.1_9 - 0.0033 17.0 0.1 8.5 6.1 0.0 3.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AAAP01003837.1_9 - 0.0044 17.0 0.1 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_26 PF13443.6 AAAP01003837.1_9 - 0.0056 17.1 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AAAP01003837.1_9 - 0.019 14.9 0.1 0.066 13.2 0.0 1.8 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AAAP01003837.1_9 - 0.029 13.9 0.4 5.5 6.6 0.0 3.3 3 1 0 3 3 3 0 Sigma-70, region 4 YdaS_antitoxin PF15943.5 AAAP01003837.1_9 - 0.036 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MqsA_antitoxin PF15731.5 AAAP01003837.1_9 - 0.037 14.1 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Pou PF00157.17 AAAP01003837.1_9 - 0.057 13.4 0.2 0.12 12.4 0.1 1.6 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain DUF1730 PF08331.10 AAAP01003837.1_10 - 9.5e-24 83.1 0.0 1.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 AAAP01003837.1_10 - 8.1e-19 68.3 3.9 1.4e-18 67.6 3.9 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01003837.1_10 - 9.8e-08 32.5 6.4 2.9e-07 31.0 6.5 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003837.1_10 - 3.2e-07 30.3 4.5 0.0025 17.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003837.1_10 - 9.5e-07 28.9 1.1 0.0023 18.1 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003837.1_10 - 0.00011 22.1 15.1 0.0043 17.1 4.0 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003837.1_10 - 0.00012 21.7 14.1 0.00016 21.4 3.0 2.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003837.1_10 - 0.0017 18.8 5.2 0.064 13.7 1.6 2.6 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003837.1_10 - 0.0025 18.3 1.7 0.16 12.5 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003837.1_10 - 0.0039 18.0 11.7 0.37 11.8 4.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003837.1_10 - 0.0043 17.1 5.1 0.0043 17.1 5.1 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003837.1_10 - 0.006 17.0 9.7 0.45 11.1 4.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003837.1_10 - 1.8 8.8 7.1 14 5.9 3.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003837.1_10 - 2 8.6 12.2 2.7 8.2 3.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain QueF PF14489.6 AAAP01003837.1_11 - 4.1e-32 110.2 0.0 5.6e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein QueF_N PF14819.6 AAAP01003837.1_11 - 0.0011 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term PfkB PF00294.24 AAAP01003837.1_12 - 1.7e-40 139.3 1.8 2.4e-40 138.7 1.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AAAP01003837.1_12 - 9.6e-14 51.8 0.0 2.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 AAAP01003837.1_12 - 7.6e-11 41.9 0.9 2e-10 40.5 0.4 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AAAP01003837.1_12 - 0.00044 19.8 2.3 0.0015 18.1 0.9 2.1 2 0 0 2 2 2 1 Carbohydrate kinase Pantoate_ligase PF02569.15 AAAP01003837.1_12 - 0.022 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Metallophos PF00149.28 AAAP01003837.1_13 - 1.2e-12 48.7 0.0 1.8e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NTP_transf_3 PF12804.7 AAAP01003837.1_13 - 0.043 14.2 0.1 0.094 13.1 0.1 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Metallophos_2 PF12850.7 AAAP01003837.1_13 - 0.095 12.9 0.1 0.18 12.0 0.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AAAP01003837.1_13 - 0.16 11.3 0.0 0.5 9.6 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily EAL PF00563.20 AAAP01003837.1_15 - 0.0022 17.5 0.4 0.0061 16.1 0.1 2.0 2 1 0 2 2 2 1 EAL domain Cdh1_DBD_1 PF18196.1 AAAP01003837.1_15 - 0.11 12.8 0.2 0.26 11.6 0.2 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Methyltransf_18 PF12847.7 AAAP01003837.1_15 - 0.13 12.2 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 AAAP01003837.1_16 - 3.1e-29 102.2 0.0 4.3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003837.1_16 - 9.6e-11 42.0 1.5 2.5e-07 30.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003837.1_16 - 0.00018 21.0 0.0 0.045 13.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MukB PF04310.12 AAAP01003837.1_16 - 0.011 15.5 1.5 0.021 14.6 1.5 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA_23 PF13476.6 AAAP01003837.1_16 - 0.027 15.0 0.0 0.031 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01003837.1_16 - 0.033 13.8 0.2 0.074 12.7 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 AAAP01003837.1_16 - 0.035 13.8 2.2 0.059 13.1 2.2 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AAAP01003837.1_16 - 0.059 12.6 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 AAAP01003837.1_16 - 0.084 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SIS PF01380.22 AAAP01003837.1_16 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 SIS domain AAA_19 PF13245.6 AAAP01003837.1_16 - 0.11 12.9 0.6 0.25 11.7 0.6 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AAAP01003837.1_16 - 0.14 12.4 0.3 0.64 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003837.1_16 - 0.2 11.6 0.3 0.38 10.7 0.3 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 AAAP01003837.1_16 - 0.23 11.1 0.0 0.78 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 AAAP01003837.1_16 - 0.38 9.4 0.0 4.8 5.7 0.3 2.0 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 AAAP01003837.1_17 - 1.5e-10 40.8 20.8 2.2e-10 40.3 20.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01003837.1_17 - 1.6e-06 27.5 18.5 2e-06 27.2 18.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein CCB1 PF12046.8 AAAP01003837.1_17 - 0.0024 17.2 3.2 0.0032 16.8 2.0 1.8 1 1 1 2 2 2 1 Cofactor assembly of complex C subunit B PrmA PF06325.13 AAAP01003837.1_18 - 3.7e-13 49.5 0.4 7.7e-13 48.5 0.4 1.6 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01003837.1_18 - 1e-07 31.7 0.1 1.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 AAAP01003837.1_18 - 1.4e-05 24.9 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 AAAP01003837.1_18 - 3.9e-05 23.4 0.0 6.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 AAAP01003837.1_18 - 4.3e-05 23.3 0.0 6.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 AAAP01003837.1_18 - 7.1e-05 23.4 0.1 0.00011 22.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003837.1_18 - 0.0081 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 AAAP01003837.1_18 - 0.032 14.0 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 DNA methylase Methyltransf_15 PF09445.10 AAAP01003837.1_18 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 AAAP01003837.1_18 - 0.18 10.9 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 AAAP01003837.1_18 - 0.21 11.4 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UbiA PF01040.18 AAAP01003837.1_19 - 1.1e-63 214.9 23.4 1.3e-63 214.6 23.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 AAAP01003837.1_19 - 0.024 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Oligosaccaryltransferase PLDc_2 PF13091.6 AAAP01003837.1_20 - 2e-40 137.8 0.0 4.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AAAP01003837.1_20 - 3.9e-05 23.6 0.2 0.084 13.1 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif EAL PF00563.20 AAAP01003837.1_21 - 1.2e-60 205.1 0.0 3e-60 203.7 0.0 1.6 2 0 0 2 2 2 1 EAL domain PAS_9 PF13426.7 AAAP01003837.1_21 - 0.00032 20.9 0.0 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAAP01003837.1_21 - 0.00036 20.7 0.0 0.00086 19.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003837.1_21 - 0.00051 20.0 0.0 0.00099 19.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003837.1_21 - 0.0043 17.3 0.0 0.033 14.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PhageMin_Tail PF10145.9 AAAP01003837.1_21 - 0.026 14.4 0.9 0.026 14.4 0.9 2.1 2 0 0 2 2 2 0 Phage-related minor tail protein Aminotran_5 PF00266.19 AAAP01003837.1_22 - 2.8e-11 43.0 0.0 4.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 AAAP01003837.1_22 - 0.011 14.6 0.0 0.93 8.3 0.0 2.4 2 1 1 3 3 3 0 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AAAP01003837.1_22 - 0.079 12.2 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase TOBE PF03459.17 AAAP01003838.1_2 - 9.3e-35 118.7 4.8 2.1e-17 63.2 0.2 2.3 2 0 0 2 2 2 2 TOBE domain HTH_1 PF00126.27 AAAP01003838.1_2 - 2e-13 50.1 0.0 5.9e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 AAAP01003838.1_2 - 0.038 13.4 0.0 0.52 9.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Molybdopterin PF00384.22 AAAP01003838.1_3 - 1.1e-27 97.1 0.0 1.5e-26 93.3 0.0 2.7 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003838.1_3 - 7e-11 42.1 0.0 1.9e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003838.1_3 - 0.21 11.6 1.5 0.43 10.6 1.5 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain FdhD-NarQ PF02634.15 AAAP01003838.1_4 - 3.9e-71 239.5 0.0 4.5e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family DUF1677 PF07911.13 AAAP01003838.1_4 - 0.048 14.0 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) Fer4_11 PF13247.6 AAAP01003838.1_5 - 1.6e-15 57.0 16.9 9.6e-12 44.9 4.0 3.6 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003838.1_5 - 4.3e-14 52.8 19.2 2.3e-06 28.1 4.7 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003838.1_5 - 1.1e-10 41.4 24.3 7.9e-07 29.1 2.7 3.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003838.1_5 - 1.6e-07 30.9 4.6 1.6e-07 30.9 4.6 5.0 6 0 0 6 6 6 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003838.1_5 - 2.9e-07 30.5 24.2 0.00071 19.7 10.6 3.3 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003838.1_5 - 1e-06 29.1 16.7 0.00045 20.7 1.1 3.9 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003838.1_5 - 1.5e-06 28.0 31.9 1.8e-06 27.8 2.5 4.4 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003838.1_5 - 1.9e-06 27.6 10.8 0.00014 21.8 1.5 4.4 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003838.1_5 - 8.1e-05 22.8 33.5 0.011 16.2 2.4 4.5 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003838.1_5 - 0.00011 22.6 20.0 0.018 15.5 0.9 3.7 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003838.1_5 - 0.0005 20.8 36.4 0.29 12.2 5.9 4.4 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003838.1_5 - 0.0027 18.6 22.4 0.83 10.6 4.4 4.4 4 1 0 4 4 4 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AAAP01003838.1_5 - 0.0075 17.0 1.1 0.0075 17.0 1.1 2.9 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 AAAP01003838.1_5 - 0.035 14.2 5.3 0.035 14.2 5.3 3.7 2 1 2 4 4 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003838.1_5 - 2.5 9.0 19.3 0.46 11.4 1.6 3.3 2 1 2 4 4 4 0 4Fe-4S dicluster domain NrfD PF03916.14 AAAP01003838.1_6 - 1.2e-05 25.2 4.9 1.6e-05 24.7 4.9 1.1 1 0 0 1 1 1 1 Polysulphide reductase, NrfD EAL PF00563.20 AAAP01003838.1_7 - 1.6e-43 149.0 0.0 2e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 EAL domain SATase_N PF06426.14 AAAP01003838.1_8 - 2e-32 111.7 0.2 3e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 AAAP01003838.1_8 - 2.3e-08 33.4 2.0 3.8e-06 26.4 0.8 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Bactofilin PF04519.13 AAAP01003838.1_8 - 0.084 13.2 1.0 0.14 12.5 1.0 1.3 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Hexapep_2 PF14602.6 AAAP01003838.1_8 - 2.3 8.1 4.2 0.85 9.4 1.1 1.8 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF2325 PF10087.9 AAAP01003838.1_9 - 1.1e-24 86.3 0.0 1.3e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) Aminotran_5 PF00266.19 AAAP01003838.1_11 - 0.02 13.9 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V FeoB_N PF02421.18 AAAP01003838.1_14 - 1.7e-52 177.1 0.0 2.5e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Gate PF07670.14 AAAP01003838.1_14 - 8.2e-44 148.5 14.6 2.3e-30 105.1 0.4 2.9 2 0 0 2 2 2 2 Nucleoside recognition FeoB_C PF07664.12 AAAP01003838.1_14 - 3.1e-18 65.2 0.6 3.1e-18 65.2 0.6 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B C terminus MMR_HSR1 PF01926.23 AAAP01003838.1_14 - 1e-16 61.0 0.0 2.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_Cyto PF17910.1 AAAP01003838.1_14 - 2.9e-16 59.8 0.4 7.1e-16 58.5 0.1 1.9 2 0 0 2 2 2 1 FeoB cytosolic helical domain AIG1 PF04548.16 AAAP01003838.1_14 - 7.6e-05 22.1 0.1 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 AAAP01003838.1_14 - 0.0046 17.0 0.1 1.4 9.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 AAAP01003838.1_14 - 0.018 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoA PF04023.14 AAAP01003838.1_15 - 2.2e-14 53.4 0.1 2.5e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 FeoA domain OprB PF04966.12 AAAP01003838.1_16 - 3.5e-68 230.7 6.3 4.6e-68 230.3 6.3 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Pkinase PF00069.25 AAAP01003838.1_17 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 AAAP01003838.1_17 - 0.0019 18.2 1.5 0.0058 16.6 0.4 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 AAAP01003838.1_17 - 0.12 12.0 0.0 0.89 9.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 AAAP01003838.1_17 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SpoIIE PF07228.12 AAAP01003838.1_18 - 0.012 15.5 0.0 0.055 13.4 0.0 1.9 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 AAAP01003838.1_18 - 0.083 12.5 0.1 0.48 10.0 0.1 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C VWA_2 PF13519.6 AAAP01003838.1_19 - 0.06 14.0 0.0 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF2975 PF11188.8 AAAP01003838.1_20 - 0.016 15.1 2.8 0.039 13.8 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DASH_Dad4 PF08650.10 AAAP01003838.1_20 - 0.022 14.7 0.5 0.76 9.8 0.1 2.8 2 1 1 3 3 3 0 DASH complex subunit Dad4 Wzy_C PF04932.15 AAAP01003838.1_20 - 0.028 14.1 0.4 0.036 13.7 0.4 1.2 1 0 0 1 1 1 0 O-Antigen ligase CARD PF00619.21 AAAP01003838.1_20 - 0.063 13.3 0.3 0.47 10.5 0.3 2.5 1 1 0 1 1 1 0 Caspase recruitment domain ImpA_N PF06812.12 AAAP01003838.1_20 - 0.12 12.5 0.9 4.4 7.4 0.1 2.5 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system DUF3561 PF12084.8 AAAP01003838.1_20 - 0.13 12.3 1.7 0.22 11.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) Talin_middle PF09141.10 AAAP01003838.1_20 - 0.45 10.5 14.4 0.15 12.1 3.1 2.9 2 1 1 3 3 3 0 Talin, middle domain MCR PF18509.1 AAAP01003838.1_21 - 3.5e-26 90.5 13.6 2.9e-13 49.1 4.8 2.6 2 0 0 2 2 2 2 Magnetochrome domain Nudix_N_2 PF14803.6 AAAP01003838.1_21 - 0.014 15.3 2.5 0.81 9.7 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal CCP_MauG PF03150.14 AAAP01003838.1_21 - 0.054 14.1 0.2 5.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase DUF1924 PF09086.11 AAAP01003838.1_21 - 0.056 13.8 0.9 4.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Paired_CXXCH_1 PF09699.10 AAAP01003838.1_21 - 0.19 11.5 1.2 18 5.2 0.1 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_CBB3 PF13442.6 AAAP01003838.1_21 - 0.59 10.5 4.6 25 5.3 3.7 2.7 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003838.1_21 - 1.7 9.8 4.3 61 4.8 4.3 2.3 1 1 0 1 1 1 0 Cytochrome c MFS_1 PF07690.16 AAAP01003838.1_22 - 4.2e-21 75.3 62.0 5.5e-10 38.7 22.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferric_reduct PF01794.19 AAAP01003838.1_22 - 3.3e-15 56.3 4.5 3.3e-15 56.3 4.5 3.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component OATP PF03137.20 AAAP01003838.1_22 - 0.004 15.5 5.0 0.63 8.3 0.1 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family YfhO PF09586.10 AAAP01003838.1_22 - 6.2 4.9 16.5 0.024 12.9 2.1 2.2 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Tubulin PF00091.25 AAAP01003838.1_23 - 7.2e-42 143.8 0.7 1.1e-41 143.2 0.7 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AAAP01003838.1_23 - 8.2e-36 122.2 4.5 8.2e-36 122.2 4.5 2.1 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 AAAP01003838.1_23 - 0.0012 18.1 8.4 0.0051 16.1 2.2 2.6 1 1 1 2 2 2 2 Tubulin like UPF0060 PF02694.15 AAAP01003838.1_24 - 9.4e-31 106.2 6.7 1e-30 106.1 6.7 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 AAAP01003838.1_24 - 0.0045 17.2 2.8 0.0078 16.4 0.2 2.1 1 1 2 3 3 3 1 EamA-like transporter family Cation_efflux PF01545.21 AAAP01003838.1_25 - 4.1e-37 127.8 12.4 5.9e-37 127.3 12.4 1.2 1 0 0 1 1 1 1 Cation efflux family 7TM_GPCR_Srw PF10324.9 AAAP01003838.1_25 - 0.045 13.0 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Metal_resist PF13801.6 AAAP01003838.1_25 - 0.058 13.6 3.5 0.068 13.4 0.2 2.7 1 1 1 2 2 2 0 Heavy-metal resistance Hydrolase PF00702.26 AAAP01003838.1_26 - 2e-23 83.8 1.1 3.3e-23 83.1 1.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003838.1_26 - 0.0027 18.1 0.6 0.038 14.4 0.6 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003838.1_26 - 0.052 13.3 0.9 0.079 12.7 0.9 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_2 PF00890.24 AAAP01003839.1_1 - 5.2e-74 249.8 0.4 6.5e-74 249.5 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AAAP01003839.1_1 - 3.8e-12 46.3 0.0 9.5e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 AAAP01003839.1_1 - 0.0066 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003839.1_1 - 0.0084 15.4 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003839.1_1 - 0.049 12.3 0.0 0.19 10.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein cNMP_binding PF00027.29 AAAP01003839.1_2 - 4.8e-21 74.6 0.1 7.1e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FmdA_AmdA PF03069.15 AAAP01003839.1_3 - 0.1 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family HATPase_c PF02518.26 AAAP01003839.1_4 - 3.6e-24 85.4 0.0 9.4e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003839.1_4 - 3.3e-12 46.2 0.7 3.5e-11 43.0 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAAP01003839.1_4 - 1.8e-10 41.0 0.0 4.5e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c_3 PF13589.6 AAAP01003839.1_4 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AAAP01003839.1_4 - 0.0029 17.5 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_9 PF13426.7 AAAP01003839.1_4 - 0.0058 16.9 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 AAAP01003839.1_4 - 0.0069 16.6 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003839.1_4 - 0.0077 16.2 0.0 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003839.1_4 - 0.0089 16.3 0.1 0.025 14.8 0.1 1.9 1 1 0 1 1 1 1 PAS fold TPR_11 PF13414.6 AAAP01003839.1_4 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Response_reg PF00072.24 AAAP01003839.1_5 - 0.00016 21.8 0.1 0.00019 21.6 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain CheB_methylest PF01339.17 AAAP01003839.1_6 - 1.5e-55 187.5 0.1 1.7e-55 187.4 0.1 1.0 1 0 0 1 1 1 1 CheB methylesterase Abhydrolase_6 PF12697.7 AAAP01003839.1_6 - 0.01 16.4 4.8 0.019 15.6 4.8 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LSDAT_euk PF18139.1 AAAP01003839.1_6 - 0.036 13.4 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM CheR PF01739.18 AAAP01003839.1_7 - 1.6e-41 141.9 0.0 2.3e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAAP01003839.1_7 - 3.7e-10 39.4 0.0 8.2e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_31 PF13847.6 AAAP01003839.1_7 - 0.057 13.2 0.1 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Nif11 PF07862.11 AAAP01003839.1_7 - 0.06 13.7 0.1 0.59 10.5 0.0 2.6 1 1 1 2 2 2 0 Nif11 domain Response_reg PF00072.24 AAAP01003839.1_8 - 4.9e-57 190.9 0.1 1.2e-26 93.0 0.2 3.4 3 0 0 3 3 3 3 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003839.1_8 - 7.4e-27 94.1 0.0 1.4e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003839.1_8 - 2.8e-16 59.3 0.5 2.8e-16 59.3 0.5 3.5 2 1 0 2 2 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 AAAP01003839.1_8 - 7.8e-13 48.9 1.5 1.6e-12 47.9 0.4 2.2 2 0 0 2 2 1 1 GAF domain 4HB_MCP_1 PF12729.7 AAAP01003839.1_8 - 7.1e-12 45.2 0.0 7.1e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003839.1_8 - 2.3e-09 37.5 0.7 2.3e-09 37.5 0.7 2.7 3 0 0 3 3 2 1 HAMP domain GAF PF01590.26 AAAP01003839.1_8 - 7.2e-07 29.9 0.0 3.2e-06 27.8 0.0 2.2 1 0 0 1 1 1 1 GAF domain Methyltransf_24 PF13578.6 AAAP01003839.1_8 - 0.031 15.3 0.0 2.5 9.2 0.0 3.2 2 0 0 2 2 2 0 Methyltransferase domain LpxK PF02606.14 AAAP01003839.1_8 - 0.036 13.2 0.2 0.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase HATPase_c_3 PF13589.6 AAAP01003839.1_8 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FtsJ PF01728.19 AAAP01003839.1_8 - 0.085 13.0 0.0 0.71 10.0 0.0 2.6 4 0 0 4 4 3 0 FtsJ-like methyltransferase Pribosyltran PF00156.27 AAAP01003839.1_8 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Spc7 PF08317.11 AAAP01003839.1_8 - 0.38 9.6 16.4 0.96 8.3 16.3 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 AAAP01003839.1_8 - 0.55 9.6 11.6 0.86 9.0 11.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF16 PF01519.16 AAAP01003839.1_8 - 0.71 10.4 3.3 1.7 9.1 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 CCDC53 PF10152.9 AAAP01003839.1_8 - 1.7 9.1 6.0 42 4.5 0.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex UPF0242 PF06785.11 AAAP01003839.1_8 - 3.7 7.6 10.0 7.1 6.7 10.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0449 PF15136.6 AAAP01003839.1_8 - 9.3 6.8 9.1 30 5.1 8.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Redoxin PF08534.10 AAAP01003839.1_10 - 5.3e-26 91.1 0.0 6.1e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01003839.1_10 - 9e-17 61.2 0.0 1.1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Peripla_BP_5 PF13433.6 AAAP01003839.1_10 - 0.069 12.1 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Peptidase_M20 PF01546.28 AAAP01003839.1_12 - 3.7e-42 144.4 0.0 1.2e-41 142.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AAAP01003839.1_12 - 5.7e-21 74.5 0.0 1.1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain THDPS_N_2 PF14805.6 AAAP01003839.1_13 - 1.2e-24 86.4 2.9 1.8e-24 85.7 2.9 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep_2 PF14602.6 AAAP01003839.1_13 - 1.1e-12 47.5 1.8 1.1e-12 47.5 1.8 3.6 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AAAP01003839.1_13 - 5e-12 45.0 11.6 9.2e-06 25.2 0.9 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF5484 PF17583.2 AAAP01003839.1_13 - 0.049 13.3 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5484) FKBP_C PF00254.28 AAAP01003839.1_14 - 0.00079 19.7 0.0 0.00098 19.4 0.0 1.3 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 AAAP01003839.1_15 - 6.4e-14 51.1 1.0 4.2e-06 26.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003839.1_15 - 2e-11 43.4 1.6 3.5e-07 29.8 0.0 3.8 3 1 2 5 5 4 2 TPR repeat TPR_14 PF13428.6 AAAP01003839.1_15 - 9.9e-10 38.4 26.9 7.9e-05 23.2 0.3 4.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003839.1_15 - 1.8e-09 37.0 20.5 2.1e-05 24.3 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003839.1_15 - 3.5e-09 36.1 2.1 0.0018 18.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003839.1_15 - 4.8e-09 35.8 16.4 0.00097 18.9 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003839.1_15 - 9.5e-08 32.2 20.9 3.8e-05 23.9 4.4 3.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003839.1_15 - 2.3e-06 27.6 5.3 0.037 14.4 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003839.1_15 - 3.7e-06 26.4 10.3 5.2e-05 22.6 3.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003839.1_15 - 4.4e-06 27.3 39.0 6.7e-05 23.5 4.8 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003839.1_15 - 8.8e-05 22.3 12.1 0.0014 18.5 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 AAAP01003839.1_15 - 9.6e-05 21.8 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) TPR_19 PF14559.6 AAAP01003839.1_15 - 0.00015 22.2 22.4 0.0003 21.3 1.5 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003839.1_15 - 0.0013 18.8 1.2 0.0013 18.8 1.2 3.2 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003839.1_15 - 0.0021 18.4 9.8 0.78 10.1 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.7 AAAP01003839.1_15 - 0.026 14.8 3.2 0.026 14.8 3.2 2.0 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_4 PF07721.14 AAAP01003839.1_15 - 0.05 14.2 0.8 0.05 14.2 0.8 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat DHBP_synthase PF00926.19 AAAP01003839.1_15 - 0.22 11.0 1.0 2 7.9 0.1 2.1 2 0 0 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase SNAP PF14938.6 AAAP01003839.1_15 - 0.32 10.4 5.2 0.46 9.8 5.2 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF2934 PF11154.8 AAAP01003839.1_16 - 7.6e-13 47.9 0.9 1e-12 47.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) CorA PF01544.18 AAAP01003839.1_17 - 2.5e-53 181.3 0.0 3.1e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Bactofilin PF04519.13 AAAP01003839.1_18 - 5.1e-24 84.4 8.7 9.3e-24 83.6 8.7 1.4 1 0 0 1 1 1 1 Polymer-forming cytoskeletal DUF3224 PF11528.8 AAAP01003839.1_18 - 0.029 14.2 2.4 0.052 13.4 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3224) Phage_spike PF18715.1 AAAP01003839.1_18 - 0.068 13.2 5.9 14 5.8 0.0 3.3 1 1 1 2 2 2 0 Phage spike trimer Peptidase_M23 PF01551.22 AAAP01003839.1_19 - 7e-31 106.3 1.9 1.3e-30 105.5 1.9 1.4 1 0 0 1 1 1 1 Peptidase family M23 DUF1664 PF07889.12 AAAP01003839.1_19 - 0.025 14.6 0.4 0.34 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 AAAP01003839.1_19 - 0.045 14.1 1.7 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Surfac_D-trimer PF09006.11 AAAP01003839.1_19 - 0.048 13.6 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF3510 PF12022.8 AAAP01003839.1_19 - 0.17 12.3 0.2 0.33 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) GATase1_like PF07090.11 AAAP01003839.1_20 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative glutamine amidotransferase DUF4131 PF13567.6 AAAP01003839.1_20 - 0.058 13.1 3.6 0.054 13.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4381 PF14316.6 AAAP01003839.1_20 - 0.25 11.6 2.5 0.64 10.3 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4159 PF13709.6 AAAP01003839.1_21 - 3.6e-48 163.7 0.0 4.5e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) PNTB PF02233.16 AAAP01003840.1_1 - 3e-113 379.2 1.9 3.3e-113 379.0 1.9 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AAAP01003840.1_1 - 0.012 15.4 0.3 0.092 12.5 0.3 2.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_L10 PF00466.20 AAAP01003840.1_1 - 0.063 13.4 0.0 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L10 MCPsignal PF00015.21 AAAP01003840.1_2 - 9.7e-31 106.9 37.2 8.4e-29 100.6 26.2 2.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003840.1_2 - 9.6e-05 22.6 19.1 0.43 10.9 1.4 4.2 1 1 3 4 4 4 3 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003840.1_2 - 0.0014 18.7 7.9 1.2 9.2 0.2 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 AAAP01003840.1_2 - 0.017 15.3 5.0 0.88 9.8 0.1 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TelA PF05816.11 AAAP01003840.1_2 - 0.023 13.7 7.7 0.19 10.8 2.8 2.1 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Phage_Mu_Gam PF07352.12 AAAP01003840.1_2 - 0.079 12.9 0.9 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Laminin_I PF06008.14 AAAP01003840.1_2 - 0.082 12.6 15.1 0.48 10.1 3.0 2.4 1 1 0 2 2 2 0 Laminin Domain I Dynactin_p22 PF07426.11 AAAP01003840.1_2 - 0.14 12.0 0.2 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 Dynactin subunit p22 CENP-F_leu_zip PF10473.9 AAAP01003840.1_2 - 0.17 11.9 0.5 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 AAAP01003840.1_2 - 0.21 10.9 9.2 0.26 10.6 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 AAAP01003840.1_2 - 0.59 10.1 16.0 8 6.5 4.1 3.2 2 2 1 3 3 3 0 Laminin Domain II Dynactin PF12455.8 AAAP01003840.1_2 - 0.7 9.1 6.0 0.59 9.3 0.6 2.2 2 0 0 2 2 2 0 Dynein associated protein NPV_P10 PF05531.12 AAAP01003840.1_2 - 0.85 10.1 5.4 4.2 7.9 0.3 3.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein NIT PF08376.10 AAAP01003840.1_3 - 5.3e-53 180.8 6.6 5.3e-53 180.8 6.6 1.9 2 0 0 2 2 2 1 Nitrate and nitrite sensing HAMP PF00672.25 AAAP01003840.1_3 - 7.4e-06 26.2 0.8 1.7e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 HAMP domain PatG_C PF18065.1 AAAP01003840.1_3 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 PatG C-terminal Ribosomal_S21 PF01165.20 AAAP01003840.1_4 - 1.7e-19 69.3 10.3 1.7e-19 69.3 10.3 1.7 1 1 1 2 2 2 1 Ribosomal protein S21 DUF4337 PF14235.6 AAAP01003840.1_4 - 0.96 9.5 3.1 1.1 9.3 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RF-1 PF00472.20 AAAP01003840.1_4 - 1.1 9.2 6.9 1.3 8.9 6.9 1.1 1 0 0 1 1 1 0 RF-1 domain COQ9 PF08511.11 AAAP01003840.1_5 - 3.3e-30 103.7 0.6 5.3e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 COQ9 EF-hand_7 PF13499.6 AAAP01003840.1_6 - 1.4e-06 28.7 2.6 0.0022 18.4 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 AAAP01003840.1_6 - 8.9e-06 25.5 2.2 0.0057 16.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 AAAP01003840.1_6 - 3.7e-05 23.0 0.2 8.9e-05 21.8 0.2 1.6 1 0 0 1 1 1 1 EF hand DUF2680 PF10925.8 AAAP01003840.1_6 - 0.00013 21.9 1.5 0.00092 19.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2680) EF-hand_6 PF13405.6 AAAP01003840.1_6 - 0.00024 20.8 0.2 0.0011 18.7 0.2 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 AAAP01003840.1_6 - 0.00031 20.1 0.2 0.00072 18.9 0.2 1.6 1 0 0 1 1 1 1 EF hand Fmp27_GFWDK PF10347.9 AAAP01003840.1_6 - 0.12 12.5 1.5 0.27 11.4 0.2 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1018 PF06252.12 AAAP01003840.1_6 - 0.12 13.4 0.3 2.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) EF-hand_7 PF13499.6 AAAP01003840.1_7 - 3.5e-21 75.4 0.0 3.6e-08 33.8 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 AAAP01003840.1_7 - 1.9e-19 67.7 0.9 1.5e-05 24.2 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 AAAP01003840.1_7 - 2.7e-18 64.2 1.4 0.0022 17.8 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 AAAP01003840.1_7 - 4.6e-17 61.6 0.6 0.0011 18.7 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 AAAP01003840.1_7 - 3.3e-15 54.8 3.5 3.3e-05 23.2 0.2 3.8 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 AAAP01003840.1_7 - 0.00031 21.1 0.3 6.2 7.2 0.0 3.7 2 1 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Cation_ATPase_N PF00690.26 AAAP01003840.1_7 - 0.003 17.2 0.1 4 7.2 0.0 3.0 3 0 0 3 3 3 2 Cation transporter/ATPase, N-terminus EF-hand_11 PF08976.11 AAAP01003840.1_7 - 0.0047 17.8 0.1 0.55 11.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 AAAP01003840.1_7 - 0.019 14.8 2.5 5.4 7.0 0.1 4.1 4 0 0 4 4 4 0 EF hand FtsX_ECD PF18075.1 AAAP01003840.1_7 - 0.47 11.1 3.1 3.5 8.3 0.3 3.3 3 1 1 4 4 4 0 FtsX extracellular domain RIX1 PF08167.12 AAAP01003840.1_7 - 0.6 9.8 4.8 0.14 11.9 0.6 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis TcdB_N PF12918.7 AAAP01003840.1_7 - 0.63 10.4 6.0 0.39 11.0 0.3 2.9 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain GET2 PF08690.10 AAAP01003840.1_7 - 1 9.0 24.0 8 6.0 9.5 3.1 1 1 1 3 3 3 0 GET complex subunit GET2 Nif11 PF07862.11 AAAP01003840.1_7 - 6 7.2 7.2 70 3.8 5.0 3.1 2 1 0 2 2 2 0 Nif11 domain RsbRD_N PF14361.6 AAAP01003840.1_7 - 9.6 7.0 13.1 23 5.7 0.1 4.7 2 1 2 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Sigma70_r2 PF04542.14 AAAP01003840.1_8 - 1.7e-17 62.9 1.6 3.3e-17 62.0 1.6 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAAP01003840.1_8 - 3.9e-11 42.5 0.9 7.2e-11 41.6 0.9 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003840.1_8 - 2.4e-07 30.2 0.0 1.1e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 UPF0122 PF04297.14 AAAP01003840.1_8 - 0.064 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like RskA PF10099.9 AAAP01003840.1_9 - 0.0084 16.4 1.4 0.011 16.0 1.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Metal_resist PF13801.6 AAAP01003840.1_10 - 7.2e-29 100.5 2.9 7.2e-29 100.5 2.9 1.9 1 1 1 2 2 2 1 Heavy-metal resistance PCRF PF03462.18 AAAP01003840.1_11 - 1.6e-58 197.8 1.1 1.6e-58 197.8 1.1 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AAAP01003840.1_11 - 4.2e-42 142.7 0.2 1.3e-41 141.2 0.2 1.8 1 0 0 1 1 1 1 RF-1 domain Tim44 PF04280.15 AAAP01003840.1_12 - 2.5e-19 69.9 0.0 3.3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain TetR_N PF00440.23 AAAP01003840.1_14 - 6.2e-13 48.3 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family COXG PF06240.13 AAAP01003840.1_15 - 6.1e-37 126.5 0.0 6.8e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc2 PF10604.9 AAAP01003840.1_15 - 2.6e-08 34.2 0.1 3e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EamA PF00892.20 AAAP01003840.1_16 - 1.7e-34 118.9 36.9 3.4e-22 79.1 13.8 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAAP01003840.1_16 - 0.0011 18.4 1.6 0.32 10.3 0.7 2.2 1 1 0 2 2 2 2 Triose-phosphate Transporter family Sigma70_r4 PF04545.16 AAAP01003840.1_17 - 1.1e-18 66.4 1.7 1.1e-18 66.4 1.7 2.3 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AAAP01003840.1_17 - 5.4e-16 58.1 0.1 8e-15 54.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r1_2 PF00140.20 AAAP01003840.1_17 - 1e-06 28.6 0.1 8e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 UCR_14kD PF02271.16 AAAP01003840.1_17 - 0.0084 16.1 0.2 0.039 13.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Sigma70_r4_2 PF08281.12 AAAP01003840.1_17 - 0.0093 15.6 0.8 0.053 13.2 0.3 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_31 PF13560.6 AAAP01003840.1_17 - 0.12 12.8 2.3 0.9 9.9 0.3 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003840.1_18 - 5.7e-18 64.8 0.0 7e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Citrate_synt PF00285.21 AAAP01003840.1_19 - 1.4e-130 435.5 0.0 1.7e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain tRNA-synt_1c PF00749.21 AAAP01003840.1_20 - 3.7e-90 302.0 0.0 4.7e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Competence PF03772.16 AAAP01003840.1_21 - 1.1e-67 228.2 40.8 1.1e-67 228.2 40.8 2.2 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 AAAP01003840.1_21 - 4.9e-12 45.8 3.5 4.9e-12 45.8 3.5 5.3 3 2 3 6 6 6 2 Domain of unknown function (DUF4131) HATPase_c PF02518.26 AAAP01003840.1_22 - 5.1e-23 81.7 0.0 9.6e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003840.1_22 - 4.3e-15 55.5 0.2 3.6e-14 52.5 0.1 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 AAAP01003840.1_22 - 4.5e-08 33.2 0.0 8.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Cache domain HATPase_c_5 PF14501.6 AAAP01003840.1_22 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 GHKL domain HATPase_c_3 PF13589.6 AAAP01003840.1_22 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_4TM PF16926.5 AAAP01003840.1_22 - 0.91 9.1 4.0 0.22 11.0 0.8 1.6 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase DAO PF01266.24 AAAP01003840.1_23 - 2e-51 175.6 1.1 2.3e-51 175.5 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AAAP01003840.1_23 - 0.012 14.4 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 AAAP01003840.1_23 - 0.078 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein P22_AR_C PF10548.9 AAAP01003840.1_23 - 0.16 12.2 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 P22AR C-terminal domain DAO PF01266.24 AAAP01003840.1_24 - 2.1e-15 57.1 0.1 2.1e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003840.1_24 - 4.6e-08 33.2 0.1 7.6e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 AAAP01003840.1_24 - 1.2e-07 31.5 0.0 1.2e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AAAP01003840.1_24 - 1.1e-06 29.2 0.4 1.5e-06 28.6 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01003840.1_24 - 2e-06 27.2 0.4 2.4e-06 26.9 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01003840.1_24 - 3.8e-06 26.4 0.4 4.6e-06 26.1 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AAAP01003840.1_24 - 7.8e-06 25.6 0.6 9.9e-06 25.2 0.6 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAAP01003840.1_24 - 1.1e-05 25.4 0.5 1.1e-05 25.4 0.5 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAAP01003840.1_24 - 1.8e-05 24.2 0.7 9.1e-05 21.9 1.3 1.6 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AAAP01003840.1_24 - 0.00011 21.6 0.2 0.00013 21.3 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 AAAP01003840.1_24 - 0.00047 19.3 0.5 0.00054 19.2 0.5 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 AAAP01003840.1_24 - 0.0016 17.2 0.1 0.0019 17.0 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.18 AAAP01003840.1_24 - 0.0026 18.0 0.2 0.0035 17.6 0.2 1.2 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 AAAP01003840.1_24 - 0.0028 17.8 0.0 0.0034 17.6 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 AAAP01003840.1_24 - 0.0037 17.5 0.0 0.0043 17.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 AAAP01003840.1_24 - 0.004 16.4 0.3 0.0048 16.2 0.3 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 AAAP01003840.1_24 - 0.0046 17.4 0.0 0.0048 17.3 0.0 1.1 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 AAAP01003840.1_24 - 0.0074 16.8 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 AAAP01003840.1_24 - 0.011 15.1 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.23 AAAP01003840.1_24 - 0.013 15.5 0.2 0.013 15.5 0.2 1.4 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 AAAP01003840.1_24 - 0.016 15.7 0.0 0.019 15.5 0.0 1.2 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_oxidored PF12831.7 AAAP01003840.1_24 - 0.019 14.3 0.1 0.019 14.3 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 AAAP01003840.1_24 - 0.02 15.0 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01003840.1_24 - 0.024 14.0 0.3 0.031 13.6 0.3 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 AAAP01003840.1_24 - 0.035 13.4 0.1 0.035 13.4 0.1 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_4 PF13439.6 AAAP01003840.1_24 - 0.041 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Trp_halogenase PF04820.14 AAAP01003840.1_24 - 0.053 12.4 1.0 0.065 12.1 1.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Epimerase PF01370.21 AAAP01003840.1_24 - 0.072 12.5 0.3 0.088 12.3 0.3 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family IlvN PF07991.12 AAAP01003840.1_24 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amino_oxidase PF01593.24 AAAP01003840.1_24 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase adh_short PF00106.25 AAAP01003840.1_24 - 0.16 11.4 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_9 PF13454.6 AAAP01003840.1_24 - 0.18 11.8 0.3 0.39 10.7 0.3 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding Mqo PF06039.15 AAAP01003840.1_24 - 0.21 10.1 0.1 0.25 9.9 0.1 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Carb_kinase PF01256.17 AAAP01003840.1_25 - 7.9e-50 169.6 0.3 1.3e-49 168.9 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 AAAP01003840.1_25 - 1.1e-36 126.4 0.3 1.1e-36 126.4 0.3 1.6 2 0 0 2 2 2 1 YjeF-related protein N-terminus BDV_P10 PF06515.11 AAAP01003840.1_25 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Borna disease virus P10 protein Phos_pyr_kin PF08543.12 AAAP01003840.1_25 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MCD PF05292.11 AAAP01003840.1_26 - 4.8e-111 370.4 0.0 6e-111 370.1 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 AAAP01003840.1_26 - 9.8e-29 99.3 1.6 1.7e-28 98.5 0.4 2.1 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain Protoglobin PF11563.8 AAAP01003840.1_27 - 2.1e-41 141.5 0.2 2.1e-41 141.5 0.2 2.2 2 1 1 3 3 3 1 Protoglobin MCPsignal PF00015.21 AAAP01003840.1_27 - 4.3e-34 117.8 51.6 2.5e-31 108.8 28.7 2.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 AAAP01003840.1_27 - 0.0014 18.6 16.1 0.51 10.4 2.2 4.6 3 2 0 3 3 3 2 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAAP01003840.1_27 - 0.0088 16.3 13.0 1 9.7 0.1 4.5 3 1 1 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 AAAP01003840.1_27 - 0.027 14.7 27.4 0.94 9.8 5.1 5.1 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 AAAP01003840.1_27 - 0.41 9.8 8.7 1.1 8.4 3.3 2.4 2 0 0 2 2 2 0 TMPIT-like protein BAR PF03114.18 AAAP01003840.1_27 - 0.84 9.2 8.4 1 9.0 3.3 2.5 2 0 0 2 2 2 0 BAR domain Laminin_II PF06009.12 AAAP01003840.1_27 - 0.94 9.5 30.3 0.2 11.7 3.5 4.0 1 1 2 4 4 4 0 Laminin Domain II Syntaxin_2 PF14523.6 AAAP01003840.1_27 - 0.97 9.8 13.0 8.7 6.8 0.6 4.2 2 2 1 3 3 3 0 Syntaxin-like protein COMMD1_N PF17221.3 AAAP01003840.1_27 - 2.7 8.3 9.7 0.17 12.2 1.2 3.1 2 2 1 4 4 4 0 COMMD1 N-terminal domain Laminin_I PF06008.14 AAAP01003840.1_27 - 3.5 7.3 34.3 0.11 12.1 7.8 4.1 1 1 2 4 4 4 0 Laminin Domain I KORA PF16509.5 AAAP01003840.1_27 - 4.4 7.7 14.7 0.12 12.7 0.8 3.9 3 1 1 4 4 4 0 TrfB plasmid transcriptional repressor LOH1CR12 PF10158.9 AAAP01003840.1_27 - 4.6 7.3 9.2 15 5.6 0.1 3.0 2 1 0 2 2 2 0 Tumour suppressor protein AIP3 PF03915.13 AAAP01003840.1_27 - 6.9 5.7 18.9 4.9 6.1 3.1 2.3 1 1 1 2 2 2 0 Actin interacting protein 3 ADIP PF11559.8 AAAP01003840.1_27 - 9.6 6.3 13.2 0.083 13.0 2.6 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Trigger_C PF05698.14 AAAP01003840.1_28 - 5.3e-39 133.8 1.3 5.3e-39 133.8 1.3 2.6 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus Trigger_N PF05697.13 AAAP01003840.1_28 - 4.1e-37 127.7 3.0 8.9e-37 126.6 1.2 2.5 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) FKBP_C PF00254.28 AAAP01003840.1_28 - 9.2e-12 45.1 0.3 3.1e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase CLP_protease PF00574.23 AAAP01003840.1_29 - 1.2e-86 289.3 0.0 1.4e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease AAA_2 PF07724.14 AAAP01003840.1_30 - 2.4e-50 171.0 0.0 5.1e-50 169.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 AAAP01003840.1_30 - 2.3e-20 72.2 3.8 6.8e-20 70.7 3.8 1.9 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 AAAP01003840.1_30 - 4.1e-17 62.8 0.0 1.1e-16 61.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AAAP01003840.1_30 - 5.4e-16 58.4 0.3 1.6e-15 56.9 0.2 1.9 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAAP01003840.1_30 - 9.3e-07 28.9 0.0 1.1e-05 25.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AAAP01003840.1_30 - 1.3e-06 28.0 0.4 0.00029 20.3 0.6 2.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AAAP01003840.1_30 - 4e-06 27.2 0.2 7.7e-05 23.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AAAP01003840.1_30 - 1e-05 25.3 0.2 3.9e-05 23.4 0.2 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AAAP01003840.1_30 - 4.9e-05 22.5 0.1 8.1e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AAAP01003840.1_30 - 0.00017 21.4 0.0 0.028 14.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 AAAP01003840.1_30 - 0.00097 19.6 0.1 0.0061 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 AAAP01003840.1_30 - 0.0019 18.4 0.0 0.0057 16.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 AAAP01003840.1_30 - 0.0025 17.3 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AAAP01003840.1_30 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AAAP01003840.1_30 - 0.0054 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 AAAP01003840.1_30 - 0.0058 17.1 0.0 0.015 15.8 0.0 1.8 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.12 AAAP01003840.1_30 - 0.006 16.5 0.0 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 AAAP01003840.1_30 - 0.0079 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain PduV-EutP PF10662.9 AAAP01003840.1_30 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 AAAP01003840.1_30 - 0.012 16.0 0.0 0.034 14.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 AAAP01003840.1_30 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 AAAP01003840.1_30 - 0.013 16.0 0.1 0.067 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AAAP01003840.1_30 - 0.019 14.6 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 AAAP01003840.1_30 - 0.027 13.7 0.1 0.074 12.2 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 AAAP01003840.1_30 - 0.036 13.1 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_21 PF13304.6 AAAP01003840.1_30 - 0.039 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_3 PF07726.11 AAAP01003840.1_30 - 0.048 13.5 0.3 0.35 10.7 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAAP01003840.1_30 - 0.055 13.2 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01003840.1_30 - 0.064 13.6 0.3 3.3 8.0 0.1 2.6 2 1 1 3 3 2 0 AAA domain ATPase PF06745.13 AAAP01003840.1_30 - 0.066 12.6 0.3 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 AAAP01003840.1_30 - 0.077 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AAAP01003840.1_30 - 0.093 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 AAAP01003840.1_30 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ta0938 PF11494.8 AAAP01003840.1_30 - 0.16 12.3 0.1 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Ta0938 AAA_8 PF12780.7 AAAP01003840.1_30 - 0.23 10.8 0.0 0.56 9.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 Mob_Pre PF01076.19 AAAP01003841.1_1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme DUF3987 PF13148.6 AAAP01003841.1_2 - 8.2e-21 74.4 2.1 4.3e-18 65.5 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3987) ROQ_II PF18386.1 AAAP01003841.1_2 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Roquin II domain HIRAN PF08797.11 AAAP01003841.1_3 - 9.6e-08 31.9 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 HIRAN domain HTH_5 PF01022.20 AAAP01003841.1_4 - 4e-17 61.8 0.2 5.8e-17 61.3 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01003841.1_4 - 1.7e-13 50.4 0.3 3.9e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01003841.1_4 - 0.00053 19.8 0.6 0.001 18.9 0.2 1.7 2 0 0 2 2 2 1 MarR family DprA_WH PF17782.1 AAAP01003841.1_4 - 0.00056 20.0 1.1 0.19 11.9 0.2 2.2 2 0 0 2 2 2 2 DprA winged helix domain TrmB PF01978.19 AAAP01003841.1_4 - 0.0076 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 AAAP01003841.1_4 - 0.0089 16.2 0.0 0.023 14.9 0.0 1.7 2 0 0 2 2 2 1 PaaX-like protein HTH_38 PF13936.6 AAAP01003841.1_4 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003841.1_4 - 0.014 15.0 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AAAP01003841.1_4 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 AAAP01003841.1_4 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 AAAP01003841.1_4 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUF742 PF05331.11 AAAP01003841.1_4 - 0.04 13.7 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF742) HTH_IclR PF09339.10 AAAP01003841.1_4 - 0.045 13.6 0.3 0.08 12.8 0.3 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_29 PF13551.6 AAAP01003841.1_4 - 0.079 13.0 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Rrf2 PF02082.20 AAAP01003841.1_4 - 0.086 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 AAAP01003841.1_4 - 0.088 13.3 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AAAP01003841.1_4 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 LexA DNA binding domain HTH_DeoR PF08220.12 AAAP01003841.1_4 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF4423 PF14394.6 AAAP01003841.1_4 - 0.22 11.2 0.0 0.26 11.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Colipase PF01114.18 AAAP01003841.1_4 - 9.4 6.0 7.7 8.7 6.1 1.1 2.6 2 1 0 2 2 2 0 Colipase, N-terminal domain LMWPc PF01451.21 AAAP01003841.1_5 - 1.3e-18 67.8 0.0 1.6e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LMWPc PF01451.21 AAAP01003841.1_6 - 4.1e-19 69.4 0.0 5.1e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SBF PF01758.16 AAAP01003841.1_7 - 1.3e-35 122.9 15.9 1.3e-35 122.9 15.9 2.4 1 1 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 AAAP01003841.1_7 - 8.7e-07 28.5 25.9 1.1e-06 28.2 25.9 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) PetL PF05115.14 AAAP01003841.1_7 - 3.7 7.6 9.0 17 5.5 1.8 3.7 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) ArsC PF03960.15 AAAP01003841.1_8 - 1.3e-19 69.9 0.0 1.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AAAP01003841.1_8 - 0.007 16.6 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin ArsD PF06953.11 AAAP01003841.1_9 - 1.1e-43 148.5 0.1 1.2e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 Arsenical resistance operon trans-acting repressor ArsD ArsA_ATPase PF02374.15 AAAP01003841.1_10 - 1.7e-89 300.0 0.0 1.3e-48 165.8 0.0 4.1 2 2 1 3 3 3 3 Anion-transporting ATPase CbiA PF01656.23 AAAP01003841.1_10 - 1.7e-20 73.3 0.2 3.3e-09 36.9 0.0 2.4 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003841.1_10 - 4.1e-18 65.9 0.0 1.7e-10 41.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain ParA PF10609.9 AAAP01003841.1_10 - 2.7e-12 46.7 5.4 7.8e-06 25.5 1.1 3.1 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AAAP01003841.1_10 - 3.8e-11 42.9 0.1 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhoH PF02562.16 AAAP01003841.1_10 - 9.7e-09 35.0 0.3 0.0019 17.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein CBP_BcsQ PF06564.12 AAAP01003841.1_10 - 2e-08 34.0 0.7 0.0016 18.0 0.0 2.5 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ IstB_IS21 PF01695.17 AAAP01003841.1_10 - 1.3e-07 31.5 4.5 0.0055 16.5 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein MeaB PF03308.16 AAAP01003841.1_10 - 4.8e-07 29.0 4.9 0.00084 18.4 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AAAP01003841.1_10 - 2.4e-06 27.3 2.3 0.0021 17.7 0.1 3.2 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AAAP01003841.1_10 - 4.1e-06 26.5 5.2 0.013 15.0 2.5 2.8 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 AAAP01003841.1_10 - 1.6e-05 24.7 4.0 0.0016 18.2 0.7 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 AAAP01003841.1_10 - 9.6e-05 22.8 6.0 0.017 15.5 0.4 2.9 2 2 0 2 2 2 2 AAA ATPase domain MipZ PF09140.11 AAAP01003841.1_10 - 0.0011 18.3 5.4 0.021 14.1 1.2 2.7 3 0 0 3 3 2 1 ATPase MipZ APS_kinase PF01583.20 AAAP01003841.1_10 - 0.0014 18.6 1.1 0.9 9.4 0.1 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase YjeF_N PF03853.15 AAAP01003841.1_10 - 0.0025 17.7 2.7 0.6 10.0 0.2 2.9 3 0 0 3 3 3 1 YjeF-related protein N-terminus NB-ARC PF00931.22 AAAP01003841.1_10 - 0.0029 16.8 0.9 1.5 7.9 0.1 2.2 2 0 0 2 2 2 2 NB-ARC domain Mg_chelatase PF01078.21 AAAP01003841.1_10 - 0.0043 16.4 2.6 0.028 13.8 0.4 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AdoHcyase_NAD PF00670.21 AAAP01003841.1_10 - 0.0044 17.1 2.2 0.2 11.7 0.5 2.3 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AAA PF00004.29 AAAP01003841.1_10 - 0.0092 16.4 1.7 0.6 10.5 0.3 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer2_4 PF13510.6 AAAP01003841.1_10 - 0.021 14.8 0.0 0.077 13.1 0.0 2.0 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain VirC1 PF07015.11 AAAP01003841.1_10 - 0.024 14.0 1.4 4 6.7 0.1 2.4 2 0 0 2 2 2 0 VirC1 protein Glyco_transf_4 PF13439.6 AAAP01003841.1_10 - 0.04 13.9 0.1 0.24 11.4 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 AAA_7 PF12775.7 AAAP01003841.1_10 - 0.042 13.4 0.2 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 AAAP01003841.1_10 - 0.046 13.4 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003841.1_10 - 0.051 13.5 3.0 5.9 6.8 0.3 2.8 2 1 1 3 3 3 0 RsgA GTPase PIF1 PF05970.14 AAAP01003841.1_10 - 0.054 12.7 0.1 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase CTP_synth_N PF06418.14 AAAP01003841.1_10 - 0.088 12.1 0.3 5.3 6.3 0.1 2.2 2 0 0 2 2 2 0 CTP synthase N-terminus ABC_tran PF00005.27 AAAP01003841.1_10 - 0.1 13.1 0.0 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 AAAP01003841.1_10 - 0.11 12.7 0.2 17 5.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain adh_short_C2 PF13561.6 AAAP01003841.1_10 - 0.2 11.2 2.4 0.4 10.2 0.7 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ATP_bind_1 PF03029.17 AAAP01003841.1_10 - 0.22 11.3 1.6 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 AAAP01003841.1_10 - 0.29 11.1 0.2 23 4.9 0.2 2.5 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AAAP01003841.1_10 - 0.36 10.7 6.4 2 8.3 0.6 2.9 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 AAAP01003841.1_10 - 0.54 10.5 1.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 AAAP01003841.1_10 - 0.67 9.2 2.0 7.1 5.8 0.5 2.5 2 0 0 2 2 2 0 Zeta toxin LpxK PF02606.14 AAAP01003841.1_10 - 0.9 8.6 3.2 6.8 5.7 0.4 2.2 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase NTPase_1 PF03266.15 AAAP01003841.1_10 - 0.92 9.4 2.6 35 4.3 0.2 2.9 3 0 0 3 3 3 0 NTPase Glyco_trans_4_4 PF13579.6 AAAP01003841.1_10 - 6.6 7.2 15.3 0.18 12.2 3.6 3.4 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain Rhodanese PF00581.20 AAAP01003841.1_11 - 7.5e-09 36.1 0.0 1e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TraW_N PF12477.8 AAAP01003841.1_11 - 0.13 12.2 1.0 0.3 11.1 1.0 1.7 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal NMT1_3 PF16868.5 AAAP01003841.1_13 - 1.7e-17 63.8 0.0 1.4e-15 57.5 0.0 2.2 1 1 1 2 2 2 2 NMT1-like family NMT1 PF09084.11 AAAP01003841.1_13 - 1.7e-08 34.7 0.0 8.1e-08 32.5 0.0 1.9 1 1 1 2 2 2 1 NMT1/THI5 like LysR_substrate PF03466.20 AAAP01003841.1_13 - 6.7e-06 25.6 0.5 4e-05 23.1 0.3 2.1 1 1 1 2 2 2 1 LysR substrate binding domain SBP_bac_3 PF00497.20 AAAP01003841.1_13 - 0.00023 20.7 0.1 0.0022 17.5 0.1 2.1 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAAP01003841.1_13 - 0.026 14.1 0.7 0.51 9.9 0.1 2.8 3 1 0 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3834 PF12916.7 AAAP01003841.1_13 - 0.054 12.7 0.0 13 5.0 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3834) Cation_efflux PF01545.21 AAAP01003841.1_14 - 3.2e-48 164.1 17.7 3.8e-48 163.9 17.7 1.1 1 0 0 1 1 1 1 Cation efflux family HopA1 PF17914.1 AAAP01003841.1_14 - 0.013 15.3 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 HopA1 effector protein family Thiolase_N PF00108.23 AAAP01003841.1_15 - 1.3e-83 280.4 0.1 1.6e-83 280.0 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAAP01003841.1_15 - 1.5e-39 134.4 3.4 2e-39 134.0 0.3 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01003841.1_15 - 0.00015 21.4 2.5 0.00029 20.5 0.7 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 AAAP01003841.1_15 - 0.0071 16.5 0.4 0.028 14.6 0.1 2.2 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thioredoxin_3 PF13192.6 AAAP01003841.1_16 - 1.9e-22 79.1 0.0 2e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 AAAP01003841.1_16 - 0.17 12.1 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin ArsP_1 PF03773.13 AAAP01003841.1_17 - 2.4e-68 230.4 18.5 2.7e-68 230.3 18.5 1.0 1 0 0 1 1 1 1 Predicted permease NEMP PF10225.9 AAAP01003841.1_17 - 2.4 7.8 11.6 0.039 13.6 1.0 2.4 1 1 1 2 2 2 0 NEMP family HTH_5 PF01022.20 AAAP01003841.1_18 - 3.3e-12 46.1 0.0 6.6e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01003841.1_18 - 7.8e-09 35.5 0.1 1.1e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.6 AAAP01003841.1_18 - 0.0042 17.2 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AAAP01003841.1_18 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAAP01003841.1_18 - 0.033 14.5 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator TFIIE_alpha PF02002.17 AAAP01003841.1_18 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit Cytochrome_C7 PF14522.6 AAAP01003841.1_19 - 1.8e-06 27.8 15.6 0.072 13.1 15.9 2.8 1 1 1 2 2 2 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003841.1_19 - 9.8e-06 25.2 18.8 0.0019 17.9 1.4 4.1 1 1 3 4 4 4 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 AAAP01003841.1_19 - 3.5e-05 24.2 13.5 0.0017 18.8 1.7 2.7 1 1 1 2 2 2 2 Cytochrome c3 Cytochrom_CIII PF02085.16 AAAP01003841.1_19 - 6.5e-05 23.2 11.1 0.0022 18.3 1.0 2.4 1 1 1 2 2 2 2 Class III cytochrome C family Cytochrome_C554 PF13435.6 AAAP01003841.1_19 - 0.0058 17.5 19.7 0.54 11.2 11.5 3.7 1 1 0 2 2 2 1 Cytochrome c554 and c-prime zinc_ribbon_6 PF14599.6 AAAP01003841.1_19 - 0.039 14.0 3.7 2.4 8.2 0.5 2.8 2 1 1 3 3 3 0 Zinc-ribbon Cytochrom_NNT PF03264.14 AAAP01003841.1_19 - 0.44 10.2 18.0 0.13 11.9 3.3 3.0 1 1 2 3 3 3 0 NapC/NirT cytochrome c family, N-terminal region Cytochrome_CBB3 PF13442.6 AAAP01003841.1_19 - 1.5 9.2 27.0 1.8 9.0 0.2 5.3 1 1 4 5 5 5 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C552 PF02335.15 AAAP01003841.1_19 - 2.1 7.2 14.0 1.7 7.4 0.1 3.0 1 1 2 3 3 3 0 Cytochrome c552 zf-CHY PF05495.12 AAAP01003841.1_19 - 6.6 7.3 13.1 53 4.4 5.8 3.1 1 1 2 3 3 3 0 CHY zinc finger DnaJ_CXXCXGXG PF00684.19 AAAP01003841.1_19 - 7.6 7.0 10.5 0.51 10.7 2.8 2.5 1 1 1 2 2 2 0 DnaJ central domain TauE PF01925.19 AAAP01003841.1_20 - 6e-23 81.7 50.4 8.7e-23 81.2 50.4 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE MerE PF05052.12 AAAP01003841.1_20 - 1.3 9.0 11.2 0.5 10.3 0.6 3.6 3 1 0 3 3 3 0 MerE protein HTH_1 PF00126.27 AAAP01003841.1_21 - 8.3e-12 44.9 0.7 3.6e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AAAP01003841.1_22 - 2.4e-16 59.5 0.3 3.3e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AAAP01003841.1_22 - 2.2e-07 30.6 0.0 4.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AAAP01003841.1_22 - 5.2e-05 23.1 0.3 7.3e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AAAP01003841.1_22 - 0.00019 20.9 0.0 0.00075 19.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 AAAP01003841.1_22 - 0.00062 19.3 0.0 0.00094 18.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_Crp_2 PF13545.6 AAAP01003841.1_22 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AAAP01003841.1_22 - 0.0023 18.2 0.0 0.0036 17.6 0.0 1.3 1 1 0 1 1 1 1 Transcriptional regulator Penicillinase_R PF03965.16 AAAP01003841.1_22 - 0.0058 17.0 0.0 0.0066 16.8 0.0 1.1 1 0 0 1 1 1 1 Penicillinase repressor HTH_28 PF13518.6 AAAP01003841.1_22 - 0.0076 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01003841.1_22 - 0.012 15.4 0.3 0.033 14.0 0.3 1.8 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_10 PF04967.12 AAAP01003841.1_22 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_11 PF08279.12 AAAP01003841.1_22 - 0.02 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 AAAP01003841.1_22 - 0.027 14.7 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 AAAP01003841.1_22 - 0.044 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TrmB PF01978.19 AAAP01003841.1_22 - 0.045 13.6 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.15 AAAP01003841.1_22 - 0.048 13.7 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase RP-C PF03428.13 AAAP01003841.1_22 - 0.1 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_34 PF13601.6 AAAP01003841.1_22 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_40 PF14493.6 AAAP01003841.1_22 - 0.16 12.4 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_31 PF13847.6 AAAP01003841.1_23 - 7.2e-35 120.0 0.0 1.1e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003841.1_23 - 3.3e-22 79.0 0.1 1.6e-21 76.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003841.1_23 - 4.3e-21 75.4 0.4 1e-20 74.2 0.0 1.8 3 0 0 3 3 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003841.1_23 - 8.6e-20 71.1 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 AAAP01003841.1_23 - 6e-10 39.8 0.0 1.1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAAP01003841.1_23 - 3e-09 36.9 0.1 5.5e-09 36.1 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 AAAP01003841.1_23 - 4.2e-09 36.4 0.0 1e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AAAP01003841.1_23 - 6.8e-06 25.2 0.0 3.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AAAP01003841.1_23 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AAAP01003841.1_23 - 3.2e-05 23.5 0.2 4.9e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01003841.1_23 - 3.8e-05 23.3 0.1 6.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 AAAP01003841.1_23 - 0.00012 22.0 0.3 0.00037 20.4 0.2 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase UPF0020 PF01170.18 AAAP01003841.1_23 - 0.00057 19.6 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 AAAP01003841.1_23 - 0.0037 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 AAAP01003841.1_23 - 0.018 15.0 0.1 0.058 13.4 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase SymE_toxin PF08845.10 AAAP01003841.1_23 - 0.021 14.9 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system FtsJ PF01728.19 AAAP01003841.1_23 - 0.029 14.5 0.0 0.054 13.6 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 AAAP01003841.1_23 - 0.035 13.4 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 AAAP01003841.1_23 - 0.088 12.3 0.0 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase GidB PF02527.15 AAAP01003841.1_23 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G GntP_permease PF02447.16 AAAP01003841.1_24 - 1.6e-13 50.2 20.5 6.5e-10 38.3 10.1 3.1 2 1 0 3 3 3 3 GntP family permease 7TM-7TMR_HD PF07698.11 AAAP01003841.1_24 - 0.26 11.0 20.6 0.041 13.7 6.7 3.0 3 1 0 3 3 3 0 7TM receptor with intracellular HD hydrolase Sigma70_r2 PF04542.14 AAAP01003841.1_25 - 9.6e-14 50.9 0.6 1.7e-13 50.1 0.6 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAAP01003841.1_25 - 5.8e-11 41.9 0.2 1e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003841.1_25 - 3.4e-07 29.7 0.1 7.1e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Gmad1 PF10647.9 AAAP01003841.1_25 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain MFS_1 PF07690.16 AAAP01003841.1_26 - 4.5e-29 101.5 83.5 8.3e-24 84.2 46.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01003841.1_26 - 0.00096 18.1 24.4 0.072 11.9 15.1 2.1 1 1 1 2 2 2 2 MFS_1 like family CMD PF02627.20 AAAP01003841.1_28 - 2e-16 59.8 3.5 4.2e-08 33.1 0.2 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family HTH_8 PF02954.19 AAAP01003841.1_29 - 2.2e-13 49.7 0.3 4.1e-13 48.9 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 AAAP01003841.1_29 - 3.4e-05 23.4 0.0 6.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 AAAP01003841.1_29 - 0.1 12.3 0.5 0.4 10.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) TonB_C PF03544.14 AAAP01003842.1_3 - 8.8e-22 77.3 0.0 1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAAP01003842.1_3 - 0.00046 20.4 0.1 0.00073 19.7 0.1 1.4 1 1 0 1 1 1 1 TonB C terminal MotA_ExbB PF01618.16 AAAP01003842.1_4 - 2.8e-33 114.4 0.8 4.4e-33 113.7 0.8 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AAAP01003842.1_5 - 2e-25 89.5 0.1 2.4e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TauD PF02668.16 AAAP01003842.1_5 - 0.08 12.7 0.0 0.092 12.5 0.0 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DUF4070 PF13282.6 AAAP01003842.1_6 - 1.4e-08 34.9 0.0 1.9e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) Radical_SAM PF04055.21 AAAP01003842.1_6 - 0.02 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Radical_SAM PF04055.21 AAAP01003842.1_7 - 1.5e-08 35.2 0.0 2.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003842.1_7 - 2.3e-06 27.6 0.1 4.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 B12 binding domain Response_reg PF00072.24 AAAP01003842.1_8 - 2e-24 85.9 0.0 2.8e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003842.1_8 - 4.8e-17 61.2 0.2 8.4e-17 60.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003842.1_8 - 0.00034 20.2 0.2 0.00055 19.5 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 AAAP01003842.1_8 - 0.025 14.7 0.1 0.076 13.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003842.1_8 - 0.032 14.1 0.1 0.074 12.9 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain TadZ_N PF16968.5 AAAP01003842.1_8 - 0.044 13.5 0.2 0.083 12.6 0.2 1.4 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal SpoVS PF04232.12 AAAP01003842.1_8 - 0.075 12.8 0.1 0.33 10.7 0.1 2.0 1 1 1 2 2 2 0 Stage V sporulation protein S (SpoVS) HTH_38 PF13936.6 AAAP01003842.1_8 - 0.087 12.6 0.2 7 6.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Coatamer_beta_C PF07718.12 AAAP01003842.1_8 - 0.19 11.6 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta C-terminal region HisKA_3 PF07730.13 AAAP01003842.1_9 - 4.7e-12 46.2 0.3 4.7e-12 46.2 0.3 2.5 2 0 0 2 2 2 1 Histidine kinase PAS_9 PF13426.7 AAAP01003842.1_9 - 4.6e-07 30.0 0.0 7.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain HATPase_c PF02518.26 AAAP01003842.1_9 - 1.8e-06 28.5 0.3 1.8e-05 25.2 0.3 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003842.1_9 - 0.012 15.5 0.4 0.061 13.3 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain PAS PF00989.25 AAAP01003842.1_9 - 0.02 14.9 0.0 0.054 13.5 0.0 1.8 1 1 0 1 1 1 0 PAS fold PAS_4 PF08448.10 AAAP01003842.1_9 - 0.031 14.5 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 AAAP01003842.1_10 - 1.1e-31 110.2 0.0 1.7e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAAP01003842.1_10 - 1.2e-18 67.4 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 AAAP01003842.1_10 - 1e-05 25.0 0.0 0.00054 19.4 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 AAAP01003842.1_10 - 3.7e-05 23.8 0.4 0.00011 22.2 0.1 1.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AAAP01003842.1_10 - 0.00089 18.1 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 AAAP01003842.1_10 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Big_9 PF17963.1 AAAP01003842.1_11 - 1.6e-156 509.5 519.0 3e-15 56.7 13.7 27.4 26 2 0 26 26 25 20 Bacterial Ig domain Cadherin_5 PF17892.1 AAAP01003842.1_11 - 3.1e-115 376.6 328.2 2.3e-33 114.0 8.2 27.7 25 5 0 25 25 25 15 Cadherin-like domain Cadherin_4 PF17803.1 AAAP01003842.1_11 - 2.7e-102 335.5 496.7 1.4e-12 48.0 12.8 29.5 26 2 2 28 28 25 21 Bacterial cadherin-like domain HemolysinCabind PF00353.19 AAAP01003842.1_11 - 9.2e-35 118.2 131.3 1.1e-07 31.7 5.6 12.5 9 1 2 11 11 11 9 RTX calcium-binding nonapeptide repeat (4 copies) DUF4114 PF13448.6 AAAP01003842.1_11 - 3.4e-06 27.8 2.8 3.5e-05 24.5 0.7 4.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4114) DUF5643 PF18705.1 AAAP01003842.1_11 - 1.9e-05 24.6 60.2 1.1 9.2 0.2 13.4 14 0 0 14 14 14 6 Family of unknown function (DUF5643) Bombesin PF02044.17 AAAP01003842.1_11 - 0.074 13.1 14.8 30 5.0 0.3 5.4 4 0 0 4 4 4 0 Bombesin-like peptide DUF1573 PF07610.11 AAAP01003842.1_11 - 0.92 9.6 7.7 67 3.6 0.1 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1573) DUF4959 PF16323.5 AAAP01003842.1_11 - 1.8 8.9 12.4 3.5e+02 1.5 0.0 7.8 7 0 0 7 7 7 0 Domain of unknown function (DUF4959) YbbR PF07949.12 AAAP01003842.1_11 - 4.3 7.7 49.7 15 6.0 0.0 15.1 14 5 1 15 15 15 0 YbbR-like protein Phage_Mu_Gp45 PF06890.12 AAAP01003842.1_11 - 8.8 6.1 21.0 61 3.4 0.3 7.0 5 0 0 5 5 5 0 Bacteriophage Mu Gp45 protein MCPsignal PF00015.21 AAAP01003842.1_13 - 8.4e-30 103.8 33.5 1.8e-28 99.5 20.3 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_3 PF14827.6 AAAP01003842.1_13 - 3.6e-26 92.3 0.1 1.7e-25 90.1 0.0 2.2 2 0 0 2 2 2 1 Double sensory domain of two-component sensor kinase HAMP PF00672.25 AAAP01003842.1_13 - 1.7e-12 47.5 3.0 1.1e-11 45.0 0.6 3.5 3 0 0 3 3 3 1 HAMP domain DUF948 PF06103.11 AAAP01003842.1_13 - 0.026 14.8 12.8 0.42 10.9 1.0 4.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003842.1_13 - 0.034 14.2 0.7 0.034 14.2 0.7 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) PAS_6 PF08348.11 AAAP01003842.1_13 - 0.095 12.6 1.2 0.21 11.4 0.6 1.9 2 0 0 2 2 2 0 YheO-like PAS domain Ferritin PF00210.24 AAAP01003842.1_13 - 0.11 12.5 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 Ferritin-like domain NPV_P10 PF05531.12 AAAP01003842.1_13 - 0.25 11.8 4.4 26 5.4 0.2 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 AAAP01003842.1_13 - 0.41 11.1 6.7 0.55 10.6 2.7 2.7 1 1 1 2 2 2 0 Fez1 Dor1 PF04124.12 AAAP01003842.1_13 - 0.59 8.8 5.1 1.1 7.9 3.6 2.1 1 1 0 2 2 2 0 Dor1-like family BLOC1_2 PF10046.9 AAAP01003842.1_13 - 2.5 8.5 7.4 3.3 8.1 0.1 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5304 PF17230.2 AAAP01003842.1_13 - 3.6 7.8 10.5 1.3 9.3 0.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5304) CheB_methylest PF01339.17 AAAP01003842.1_14 - 2.1e-52 177.3 0.3 4e-52 176.4 0.3 1.5 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 AAAP01003842.1_14 - 1.8e-20 73.1 0.1 4.1e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.18 AAAP01003842.1_15 - 1.1e-53 181.7 0.0 1.6e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 AAAP01003842.1_15 - 0.0041 17.8 0.3 1.2 9.9 0.0 3.0 3 1 1 4 4 4 1 Methyltransferase domain TPR_6 PF13174.6 AAAP01003842.1_15 - 0.0068 17.0 0.7 0.061 14.0 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat CheR_N PF03705.15 AAAP01003842.1_15 - 0.013 15.3 0.0 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain TPR_2 PF07719.17 AAAP01003842.1_15 - 0.016 15.3 9.4 0.38 11.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003842.1_15 - 0.087 13.2 0.1 4 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003842.1_15 - 0.098 12.5 0.1 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003842.1_15 - 0.1 13.2 4.3 0.35 11.4 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003842.1_15 - 1.6 9.5 16.9 0.22 12.2 0.8 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003842.1_15 - 2.4 8.5 5.0 9.7 6.6 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Response_reg PF00072.24 AAAP01003842.1_16 - 2.6e-24 85.5 0.1 6.7e-24 84.2 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 AAAP01003842.1_16 - 1.1e-18 67.3 0.0 4.3e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 Hpt domain CheW PF01584.19 AAAP01003842.1_16 - 1.5e-17 63.5 1.4 4.8e-17 61.9 1.4 1.9 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AAAP01003842.1_16 - 8.5e-16 58.5 0.0 1.8e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAAP01003842.1_16 - 4e-11 43.1 1.6 1.5e-10 41.3 1.6 2.0 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain Rx_N PF18052.1 AAAP01003842.1_16 - 0.056 13.7 0.4 0.41 11.0 0.1 2.3 2 0 0 2 2 2 0 Rx N-terminal domain Response_reg PF00072.24 AAAP01003842.1_17 - 3.3e-17 62.6 0.1 3.9e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AAAP01003842.1_17 - 0.0038 17.6 0.0 0.0047 17.3 0.0 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Ins134_P3_kin_N PF17927.1 AAAP01003842.1_17 - 0.17 12.3 0.0 0.5 10.8 0.0 1.8 1 1 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain GGDEF PF00990.21 AAAP01003842.1_18 - 2e-41 141.5 0.0 3.2e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAAP01003842.1_18 - 2.6e-38 130.6 0.0 8.7e-23 80.6 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Hpt PF01627.23 AAAP01003842.1_18 - 3.6e-07 30.4 0.2 1.2e-06 28.7 0.2 1.9 1 0 0 1 1 1 1 Hpt domain CheW PF01584.19 AAAP01003842.1_19 - 6.6e-28 97.1 0.0 8.3e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain Oxidored_q6 PF01058.22 AAAP01003842.1_19 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit CheW PF01584.19 AAAP01003842.1_20 - 2.2e-05 24.1 0.0 0.038 13.6 0.0 2.0 1 1 1 2 2 2 2 CheW-like domain UTRA PF07702.13 AAAP01003842.1_20 - 0.16 11.8 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 UTRA domain DivIC PF04977.15 AAAP01003842.1_21 - 6.8e-15 54.6 0.0 8.7e-15 54.3 0.0 1.0 1 0 0 1 1 1 1 Septum formation initiator Oxidored_q6 PF01058.22 AAAP01003842.1_23 - 3.2e-33 114.4 1.5 4.2e-33 114.0 0.9 1.5 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 AAAP01003842.1_23 - 1.8e-29 101.9 3.8 4.9e-29 100.5 1.6 2.2 2 0 0 2 2 2 1 NiFe/NiFeSe hydrogenase small subunit C-terminal TAT_signal PF10518.9 AAAP01003842.1_23 - 0.0004 20.1 0.1 0.0004 20.1 0.1 3.8 3 1 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_11 PF13247.6 AAAP01003842.1_24 - 9e-22 77.1 12.3 9e-22 77.1 12.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003842.1_24 - 7.5e-16 58.5 21.6 2.7e-08 34.3 1.4 3.1 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003842.1_24 - 1.8e-12 46.8 34.2 6.6e-07 29.1 4.3 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003842.1_24 - 8.1e-12 44.4 33.6 1.2e-06 28.1 3.8 4.8 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003842.1_24 - 9.2e-12 45.0 25.3 3.1e-05 24.0 6.7 3.1 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003842.1_24 - 2.1e-10 40.6 53.8 1.2e-05 25.3 14.0 3.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003842.1_24 - 4e-10 39.2 29.6 5.7e-05 23.0 3.4 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003842.1_24 - 3.1e-09 36.6 30.4 0.00073 19.9 3.0 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003842.1_24 - 1e-06 28.8 25.1 2e-05 24.6 9.6 3.4 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003842.1_24 - 5.7e-06 26.9 40.9 0.11 13.5 4.9 4.5 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003842.1_24 - 5.7e-05 23.5 27.4 0.00013 22.4 4.3 3.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003842.1_24 - 0.00018 22.3 30.4 0.48 11.4 3.0 4.8 2 1 3 5 5 5 3 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AAAP01003842.1_24 - 0.0056 16.5 9.7 0.0056 16.5 9.7 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AAAP01003842.1_24 - 0.0082 16.7 28.0 0.073 13.6 1.9 4.1 1 1 3 4 4 4 4 4Fe-4S dicluster domain UCR_Fe-S_N PF10399.9 AAAP01003842.1_24 - 0.017 14.4 6.0 0.055 12.8 6.0 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_18 PF13746.6 AAAP01003842.1_24 - 6.6 7.0 23.6 0.68 10.2 3.0 4.2 2 2 2 4 4 4 0 4Fe-4S dicluster domain NrfD PF03916.14 AAAP01003842.1_25 - 2.1e-05 24.3 3.5 2.1e-05 24.3 3.5 2.0 1 1 1 2 2 2 2 Polysulphide reductase, NrfD RuBisCO_small PF00101.20 AAAP01003842.1_25 - 0.18 11.8 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain SBP_bac_5 PF00496.22 AAAP01003843.1_1 - 0.084 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AAAP01003843.1_2 - 1.5e-36 125.8 11.6 1.5e-36 125.8 11.6 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TMP_2 PF06791.13 AAAP01003843.1_2 - 0.069 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF2754 PF10953.8 AAAP01003843.1_2 - 0.087 13.1 0.3 0.3 11.4 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) BPD_transp_1 PF00528.22 AAAP01003843.1_3 - 1.1e-27 97.0 9.4 1.1e-27 97.0 9.4 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AAAP01003843.1_3 - 0.00023 21.1 0.1 0.00023 21.1 0.1 4.3 5 1 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_4 PF12730.7 AAAP01003843.1_3 - 1.5 8.8 9.7 0.13 12.2 3.2 2.3 3 0 0 3 3 3 0 ABC-2 family transporter protein ABC_tran PF00005.27 AAAP01003843.1_4 - 5.6e-58 195.3 0.0 2.2e-29 102.7 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AAAP01003843.1_4 - 1.9e-12 47.6 9.3 2.8e-05 24.1 0.1 4.1 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 AAAP01003843.1_4 - 2.6e-10 40.6 0.0 4.3e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AAAP01003843.1_4 - 1.7e-09 37.5 0.0 0.0053 16.2 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AAAP01003843.1_4 - 1.3e-08 35.2 1.1 0.004 17.4 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AAAP01003843.1_4 - 7.8e-07 29.6 0.5 0.0057 17.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AAAP01003843.1_4 - 9.3e-07 28.5 1.0 0.048 13.4 0.3 2.3 2 0 0 2 2 2 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 AAAP01003843.1_4 - 0.00014 21.4 1.3 0.25 10.7 0.1 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AAAP01003843.1_4 - 0.00031 20.3 0.3 0.61 9.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 AAAP01003843.1_4 - 0.00087 19.3 0.1 1.5 8.8 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 AAAP01003843.1_4 - 0.0011 18.5 5.9 0.85 9.2 0.1 3.9 3 1 0 3 3 3 2 AAA domain Pox_A32 PF04665.12 AAAP01003843.1_4 - 0.0012 18.3 0.7 0.97 8.8 0.1 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein AAA PF00004.29 AAAP01003843.1_4 - 0.0014 19.0 0.0 3 8.3 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003843.1_4 - 0.0018 18.3 1.5 2 8.4 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) DUF87 PF01935.17 AAAP01003843.1_4 - 0.0031 17.6 1.3 0.49 10.5 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain CbiA PF01656.23 AAAP01003843.1_4 - 0.0042 17.1 0.7 2.5 8.1 0.2 2.9 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 AAAP01003843.1_4 - 0.0045 17.2 0.6 4.8 7.3 0.3 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003843.1_4 - 0.0048 16.8 1.2 2.9 7.8 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 AAAP01003843.1_4 - 0.0071 16.1 1.3 1 9.1 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 AAAP01003843.1_4 - 0.0089 15.8 0.5 2.1 8.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 AAAP01003843.1_4 - 0.0099 15.3 1.5 0.37 10.1 0.2 2.2 2 0 0 2 2 2 1 KaiC AAA_23 PF13476.6 AAAP01003843.1_4 - 0.017 15.6 0.2 4.4 7.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 AAAP01003843.1_4 - 0.02 14.1 0.3 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 AAAP01003843.1_4 - 0.021 14.7 0.4 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 AAAP01003843.1_4 - 0.022 14.5 0.2 0.62 9.8 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 AAAP01003843.1_4 - 0.023 14.0 1.0 5.7 6.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family APS_kinase PF01583.20 AAAP01003843.1_4 - 0.029 14.3 0.3 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.25 AAAP01003843.1_4 - 0.045 13.4 0.1 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 AAAP01003843.1_4 - 0.05 12.8 0.8 5 6.2 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 AAAP01003843.1_4 - 0.078 13.2 0.6 3.2 8.1 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 AAAP01003843.1_4 - 0.11 13.0 0.1 0.79 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain GvpD PF07088.11 AAAP01003843.1_4 - 0.12 11.0 0.2 4.4 5.8 0.1 2.2 2 0 0 2 2 2 0 GvpD gas vesicle protein T2SSE PF00437.20 AAAP01003843.1_4 - 0.13 11.3 0.9 2.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 AAAP01003843.1_4 - 0.15 11.7 3.2 4.3 7.0 0.0 3.1 4 0 0 4 4 3 0 Sigma-54 interaction domain TsaE PF02367.17 AAAP01003843.1_4 - 0.2 11.6 0.3 10 6.1 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 AAAP01003843.1_4 - 0.21 10.7 0.4 6.2 5.9 0.2 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_30 PF13604.6 AAAP01003843.1_4 - 0.27 10.9 1.6 4.8 6.9 0.2 2.7 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 AAAP01003843.1_4 - 0.33 10.2 1.4 0.58 9.4 0.0 1.9 2 0 0 2 2 2 0 AIG1 family AAA_13 PF13166.6 AAAP01003843.1_4 - 0.37 9.4 0.2 5.6 5.5 0.1 2.5 3 0 0 3 3 3 0 AAA domain EamA PF00892.20 AAAP01003843.1_5 - 2.3e-29 102.3 34.1 1.6e-15 57.5 17.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 AAAP01003843.1_5 - 1.2 7.3 12.8 0.18 10.1 0.4 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) FecR PF04773.13 AAAP01003843.1_6 - 0.00017 22.1 0.0 0.00032 21.3 0.0 1.4 1 0 0 1 1 1 1 FecR protein S4 PF01479.25 AAAP01003843.1_6 - 0.16 11.7 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 S4 domain AdoHcyase PF05221.17 AAAP01003843.1_7 - 1.2e-146 487.5 0.0 1.4e-146 487.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AAAP01003843.1_7 - 1.3e-81 272.4 1.2 2e-81 271.8 1.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAAP01003843.1_7 - 1.6e-06 27.6 0.0 3.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AAAP01003843.1_7 - 0.00034 20.2 0.1 0.00077 19.1 0.1 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 AAAP01003843.1_7 - 0.0078 16.1 0.3 0.019 14.9 0.3 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AAAP01003843.1_7 - 0.016 15.6 0.3 0.039 14.4 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 AAAP01003843.1_7 - 0.042 14.1 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain SpoVAE PF14097.6 AAAP01003843.1_7 - 0.068 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AE1 F420_oxidored PF03807.17 AAAP01003843.1_7 - 0.13 12.9 0.3 1.1 9.9 0.1 2.6 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent PEP-utilizers_C PF02896.18 AAAP01003843.1_8 - 1.4e-98 329.7 0.0 2.4e-98 328.9 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AAAP01003843.1_8 - 3e-28 98.3 0.7 7.8e-28 97.0 0.7 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAAP01003843.1_8 - 1.5e-18 66.2 1.8 3.9e-18 64.9 1.8 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PTS-HPr PF00381.19 AAAP01003843.1_9 - 4e-25 87.9 0.4 4.5e-25 87.7 0.4 1.1 1 0 0 1 1 1 1 PTS HPr component phosphorylation site EIIA-man PF03610.16 AAAP01003843.1_10 - 1.4e-28 99.4 0.2 1.7e-28 99.2 0.2 1.1 1 0 0 1 1 1 1 PTS system fructose IIA component Tubulin PF00091.25 AAAP01003843.1_10 - 0.037 14.2 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain ATP_bind_2 PF03668.15 AAAP01003843.1_11 - 8e-86 287.8 0.0 9.9e-86 287.5 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_30 PF13604.6 AAAP01003843.1_11 - 0.00068 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003843.1_11 - 0.0019 18.4 0.7 1 9.5 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 AAAP01003843.1_11 - 0.0021 18.6 1.3 0.1 13.2 1.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003843.1_11 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01003843.1_11 - 0.049 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003843.1_11 - 0.054 13.9 0.2 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AAAP01003843.1_11 - 0.2 12.2 0.0 0.29 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 AAAP01003843.1_11 - 0.32 9.1 0.0 0.43 8.7 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Hpr_kinase_C PF07475.12 AAAP01003843.1_12 - 1.3e-20 73.6 0.0 2.2e-20 72.9 0.0 1.4 1 1 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 AAAP01003843.1_12 - 0.034 13.9 0.2 0.057 13.2 0.2 1.4 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AAAP01003843.1_12 - 0.047 13.9 0.0 0.052 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 AAAP01003843.1_12 - 0.23 10.6 0.1 0.32 10.2 0.1 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain SLT PF01464.20 AAAP01003843.1_13 - 8.1e-24 83.5 0.0 2.9e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 Transglycosylase SLT domain TPR_2 PF07719.17 AAAP01003843.1_13 - 0.00086 19.2 0.8 0.19 11.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003843.1_13 - 0.0019 18.7 9.3 0.31 11.8 0.2 4.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003843.1_13 - 0.1 13.3 1.5 4.2 8.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1848 PF08902.11 AAAP01003843.1_14 - 4.2e-81 272.6 0.0 4.8e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) Radical_SAM PF04055.21 AAAP01003843.1_14 - 0.064 13.6 0.3 3 8.2 0.2 2.8 2 1 0 2 2 2 0 Radical SAM superfamily Aconitase_2_N PF06434.13 AAAP01003843.1_15 - 1.6e-94 315.3 0.0 2.4e-94 314.7 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 AAAP01003843.1_15 - 5.3e-61 205.2 0.1 9.5e-61 204.4 0.1 1.4 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 AAAP01003843.1_15 - 2.8e-40 138.7 0.0 1.8e-38 132.7 0.0 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Ketoacyl-synt_C PF02801.22 AAAP01003843.1_15 - 0.093 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain PDDEXK_1 PF12705.7 AAAP01003843.1_16 - 2.4e-21 76.8 0.0 6.5e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Response_reg PF00072.24 AAAP01003843.1_17 - 5.8e-26 90.9 0.0 1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003843.1_17 - 5.9e-22 77.5 0.0 3e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal PALP PF00291.25 AAAP01003843.1_17 - 0.024 14.1 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme PulG PF11773.8 AAAP01003843.1_17 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin DctP PF03480.13 AAAP01003843.1_18 - 1.6e-44 152.4 0.0 2.3e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 DctQ PF04290.12 AAAP01003843.1_19 - 9.8e-05 22.3 0.3 9.8e-05 22.3 0.3 1.9 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF997 PF06196.12 AAAP01003843.1_19 - 0.0017 18.3 1.9 0.83 9.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF997) DUF3918 PF13056.6 AAAP01003843.1_19 - 0.088 12.4 1.1 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) DUF4131 PF13567.6 AAAP01003843.1_19 - 0.13 11.9 5.0 0.16 11.6 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CT_C_D PF02682.16 AAAP01003844.1_1 - 8.4e-63 211.8 0.0 9.4e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D MCPsignal PF00015.21 AAAP01003844.1_2 - 1.7e-29 102.9 50.1 3.1e-29 102.0 29.0 4.1 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003844.1_2 - 3.3e-07 30.6 0.2 3.3e-07 30.6 0.2 4.0 3 0 0 3 3 3 1 HAMP domain 4HB_MCP_1 PF12729.7 AAAP01003844.1_2 - 0.00044 19.8 0.3 0.00044 19.8 0.3 3.3 3 1 1 4 4 4 1 Four helix bundle sensory module for signal transduction DUF1664 PF07889.12 AAAP01003844.1_2 - 0.15 12.1 15.2 0.42 10.7 0.8 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 AAAP01003844.1_2 - 3.2 7.6 6.2 4.1 7.3 0.3 3.4 3 2 1 4 4 4 0 Sec34-like family OmpA PF00691.20 AAAP01003844.1_3 - 2.1e-19 69.7 0.1 2.7e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 OmpA family PsbQ PF05757.11 AAAP01003844.1_3 - 0.014 15.1 2.2 0.035 13.8 1.7 2.0 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Pilus_CpaD PF09476.10 AAAP01003844.1_3 - 0.032 13.9 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) 3HCDH PF00725.22 AAAP01003844.1_4 - 5.5e-31 107.1 0.1 3.7e-17 62.7 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 AAAP01003844.1_4 - 3.8e-16 59.5 0.0 5.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thiolase_C PF02803.18 AAAP01003844.1_6 - 4.7e-20 71.5 0.2 1e-19 70.4 0.1 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 AAAP01003844.1_6 - 4e-19 69.0 0.0 1.3e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain MarR PF01047.22 AAAP01003844.1_7 - 4.5e-11 42.5 0.0 9.1e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01003844.1_7 - 3.3e-10 39.7 0.3 1.1e-09 38.0 0.1 2.0 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 AAAP01003844.1_7 - 8.5e-05 23.0 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAAP01003844.1_7 - 0.076 12.6 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DNA_meth_N PF18284.1 AAAP01003844.1_7 - 0.084 12.8 0.8 0.15 12.0 0.8 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain HTH_36 PF13730.6 AAAP01003844.1_7 - 0.15 12.1 0.0 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain zf-ribbon_3 PF13248.6 AAAP01003844.1_8 - 0.0018 17.6 1.1 0.0031 16.9 1.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AAAP01003844.1_8 - 0.0049 16.9 0.3 0.0075 16.3 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AAAP01003844.1_8 - 0.0063 16.2 1.2 0.0092 15.7 1.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Fzo_mitofusin PF04799.13 AAAP01003844.1_8 - 0.014 15.0 0.4 4.4 6.8 0.0 2.6 3 0 0 3 3 3 0 fzo-like conserved region CdvA PF18822.1 AAAP01003844.1_8 - 0.018 14.9 0.1 6.2 6.7 0.1 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3819 PF12842.7 AAAP01003844.1_8 - 0.036 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) CLZ PF16526.5 AAAP01003844.1_8 - 0.13 12.7 2.1 8.4 6.8 0.2 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-Di19 PF05605.12 AAAP01003844.1_8 - 0.13 12.6 1.3 0.22 11.9 1.3 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ni_hydr_CYTB PF01292.20 AAAP01003844.1_8 - 0.17 11.4 5.6 0.37 10.4 5.6 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 GspL_C PF12693.7 AAAP01003844.1_8 - 0.22 11.3 1.9 19 5.0 0.8 2.6 2 0 0 2 2 2 0 GspL periplasmic domain Prok-RING_1 PF14446.6 AAAP01003844.1_8 - 0.23 11.4 3.1 0.34 10.9 3.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 BMFP PF04380.13 AAAP01003844.1_8 - 0.71 10.4 5.3 34 5.0 3.0 2.8 2 1 0 2 2 2 0 Membrane fusogenic activity E1-E2_ATPase PF00122.20 AAAP01003844.1_8 - 0.82 9.2 0.0 0.82 9.2 0.0 2.7 2 2 0 2 2 2 0 E1-E2 ATPase UPF0547 PF10571.9 AAAP01003844.1_8 - 1.1 9.4 6.2 2.2 8.5 6.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Caps_synth_CapC PF14102.6 AAAP01003844.1_8 - 2 8.8 8.1 2.1 8.8 6.6 1.8 1 1 1 2 2 2 0 Capsule biosynthesis CapC zf-LITAF-like PF10601.9 AAAP01003844.1_8 - 6.5 7.1 7.7 0.39 11.0 1.0 2.4 3 0 0 3 3 2 0 LITAF-like zinc ribbon domain DUF2189 PF09955.9 AAAP01003844.1_10 - 1e-35 122.7 9.4 1e-35 122.7 9.4 2.5 3 0 0 3 3 3 1 Predicted integral membrane protein (DUF2189) DUF4231 PF14015.6 AAAP01003844.1_10 - 4.7 7.7 5.4 1.3 9.5 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HTH_5 PF01022.20 AAAP01003844.1_12 - 3e-17 62.2 0.3 4.8e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01003844.1_12 - 2.8e-12 46.5 2.1 4.7e-12 45.8 0.5 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01003844.1_12 - 0.0006 19.6 0.6 0.0017 18.2 0.4 1.8 2 0 0 2 2 2 1 MarR family HTH_38 PF13936.6 AAAP01003844.1_12 - 0.0043 16.8 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAAP01003844.1_12 - 0.013 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 AAAP01003844.1_12 - 0.026 14.7 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_29 PF13551.6 AAAP01003844.1_12 - 0.029 14.4 0.2 0.052 13.6 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix MarR PF01047.22 AAAP01003844.1_12 - 0.029 14.3 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 MarR family DprA_WH PF17782.1 AAAP01003844.1_12 - 0.035 14.2 2.5 0.87 9.8 0.3 2.2 2 0 0 2 2 2 0 DprA winged helix domain HTH_Crp_2 PF13545.6 AAAP01003844.1_12 - 0.077 13.0 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 AAAP01003844.1_12 - 0.095 12.3 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 AAAP01003844.1_12 - 0.097 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AAAP01003844.1_12 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 LexA DNA binding domain HTH_27 PF13463.6 AAAP01003844.1_12 - 0.13 12.8 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.20 AAAP01003844.1_12 - 0.15 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator LMWPc PF01451.21 AAAP01003844.1_13 - 6.2e-18 65.5 0.0 7.8e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LMWPc PF01451.21 AAAP01003844.1_14 - 3.3e-19 69.7 0.0 4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SBF PF01758.16 AAAP01003844.1_15 - 5e-35 120.9 15.9 5e-35 120.9 15.9 2.4 1 1 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 AAAP01003844.1_15 - 1.2e-06 28.1 23.3 1.6e-06 27.6 23.3 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) PetL PF05115.14 AAAP01003844.1_15 - 0.62 10.1 6.3 9.2 6.3 1.3 3.6 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) ArsC PF03960.15 AAAP01003844.1_16 - 2.2e-19 69.2 0.0 3.8e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AAAP01003844.1_16 - 0.0099 16.1 0.0 0.059 13.6 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin ArsD PF06953.11 AAAP01003844.1_17 - 1.5e-43 148.0 0.0 1.7e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Arsenical resistance operon trans-acting repressor ArsD ArsA_ATPase PF02374.15 AAAP01003844.1_18 - 3e-89 299.2 0.0 4.4e-48 164.0 0.0 4.0 2 2 1 3 3 3 3 Anion-transporting ATPase CbiA PF01656.23 AAAP01003844.1_18 - 2.3e-19 69.7 0.1 1.9e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003844.1_18 - 5.3e-17 62.3 0.0 1.4e-09 38.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain ParA PF10609.9 AAAP01003844.1_18 - 3e-11 43.2 6.1 2.2e-05 24.0 0.8 3.1 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AAAP01003844.1_18 - 8.7e-10 38.5 0.1 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhoH PF02562.16 AAAP01003844.1_18 - 6.9e-08 32.2 2.0 0.0005 19.6 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.6 AAAP01003844.1_18 - 1e-07 32.5 2.1 0.0023 18.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 AAAP01003844.1_18 - 1.5e-07 31.3 1.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein CBP_BcsQ PF06564.12 AAAP01003844.1_18 - 2.3e-06 27.3 2.5 0.0067 15.9 0.1 2.5 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 AAAP01003844.1_18 - 6.5e-06 25.3 5.1 0.0045 16.0 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 AAAP01003844.1_18 - 1.3e-05 24.9 4.6 0.072 12.7 1.9 2.9 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 AAAP01003844.1_18 - 8.9e-05 22.2 7.3 0.0054 16.4 0.9 3.3 3 1 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_30 PF13604.6 AAAP01003844.1_18 - 0.00014 21.7 5.7 0.0059 16.4 1.2 2.7 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 AAAP01003844.1_18 - 0.0012 18.1 1.3 0.61 9.2 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Mg_chelatase PF01078.21 AAAP01003844.1_18 - 0.0021 17.5 3.5 0.02 14.3 0.4 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 AAAP01003844.1_18 - 0.0028 17.6 0.9 1.3 8.9 0.1 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase YjeF_N PF03853.15 AAAP01003844.1_18 - 0.0039 17.1 4.6 0.37 10.6 0.3 2.8 3 0 0 3 3 3 2 YjeF-related protein N-terminus RsgA_GTPase PF03193.16 AAAP01003844.1_18 - 0.014 15.3 0.8 4.5 7.1 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 AAAP01003844.1_18 - 0.021 15.3 2.2 1.7 9.1 0.1 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CTP_synth_N PF06418.14 AAAP01003844.1_18 - 0.032 13.6 0.6 1.1 8.5 0.1 2.2 2 0 0 2 2 2 0 CTP synthase N-terminus Fer2_4 PF13510.6 AAAP01003844.1_18 - 0.036 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PIF1 PF05970.14 AAAP01003844.1_18 - 0.041 13.0 0.1 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase ABC_tran PF00005.27 AAAP01003844.1_18 - 0.053 14.0 0.1 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AdoHcyase_NAD PF00670.21 AAAP01003844.1_18 - 0.056 13.5 1.9 0.7 9.9 0.4 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ATP_bind_1 PF03029.17 AAAP01003844.1_18 - 0.056 13.2 2.2 7.5 6.3 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 AAAP01003844.1_18 - 0.062 12.8 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region VirC1 PF07015.11 AAAP01003844.1_18 - 0.079 12.2 0.7 7.5 5.8 0.0 2.3 2 0 0 2 2 2 0 VirC1 protein MipZ PF09140.11 AAAP01003844.1_18 - 0.097 11.9 7.2 0.3 10.3 2.1 2.8 3 1 0 3 3 3 0 ATPase MipZ AAA_24 PF13479.6 AAAP01003844.1_18 - 0.1 12.3 0.5 13 5.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAAP01003844.1_18 - 0.68 9.7 3.5 15 5.5 0.4 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 AAAP01003844.1_18 - 1.5 8.7 6.9 6.5 6.6 0.6 2.9 3 0 0 3 3 3 0 NACHT domain Glyco_trans_4_4 PF13579.6 AAAP01003844.1_18 - 4.1 7.8 11.9 0.63 10.5 2.3 2.9 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain FAD-oxidase_C PF02913.19 AAAP01003844.1_19 - 2.7e-67 227.0 1.2 6.5e-67 225.8 0.2 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAAP01003844.1_19 - 1.5e-38 131.6 1.4 1.5e-38 131.6 1.4 1.7 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.16 AAAP01003844.1_20 - 8.5e-40 136.8 78.6 6.1e-32 110.9 43.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01003844.1_20 - 0.00057 19.3 36.1 0.00078 18.8 36.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 AAAP01003844.1_20 - 0.0041 16.0 10.6 0.0041 16.0 10.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2732 PF10809.8 AAAP01003844.1_22 - 0.046 13.6 0.2 0.063 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) DUF326 PF03860.16 AAAP01003844.1_22 - 1.3 9.1 27.9 0.27 11.3 8.8 4.0 5 0 0 5 5 5 0 Domain of Unknown Function (DUF326) Peripla_BP_6 PF13458.6 AAAP01003844.1_23 - 7e-58 196.9 12.4 8.2e-58 196.7 12.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01003844.1_23 - 1.8e-31 109.6 0.0 2.2e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAAP01003844.1_23 - 1e-20 74.1 0.2 1.5e-20 73.5 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain PGM_PMM_I PF02878.16 AAAP01003844.1_23 - 0.003 17.3 0.1 0.066 12.9 0.2 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Bmp PF02608.14 AAAP01003844.1_23 - 0.025 13.6 0.2 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter substrate-binding protein PnrA-like Fe-ADH PF00465.19 AAAP01003844.1_23 - 0.026 13.3 0.7 0.04 12.7 0.1 1.6 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase RL10P_insert PF17777.1 AAAP01003844.1_23 - 0.07 13.1 0.0 33 4.6 0.0 3.2 2 1 1 3 3 3 0 Insertion domain in 60S ribosomal protein L10P PRCC PF10253.9 AAAP01003844.1_24 - 0.22 12.3 11.1 0.27 12.0 11.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ecl1 PF12855.7 AAAP01003844.1_24 - 0.31 12.2 2.6 0.35 12.0 2.6 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF3405 PF11885.8 AAAP01003844.1_24 - 0.61 8.6 3.8 0.66 8.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) NPL PF17800.1 AAAP01003844.1_24 - 0.67 10.5 2.4 1 9.9 2.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin-like domain BCIP PF13862.6 AAAP01003844.1_24 - 0.95 9.2 5.6 1.5 8.6 5.6 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Mitofilin PF09731.9 AAAP01003844.1_24 - 6.7 5.4 21.1 6.8 5.4 21.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF5427 PF10310.9 AAAP01003844.1_24 - 8.3 5.2 13.0 8.9 5.1 13.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) EAL PF00563.20 AAAP01003844.1_25 - 4.4e-70 235.9 0.0 9.7e-70 234.8 0.0 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003844.1_25 - 5.3e-55 185.6 0.1 1.8e-54 183.8 0.1 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003844.1_25 - 3.1e-31 107.7 0.0 4.7e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AAAP01003844.1_25 - 7.5e-28 96.8 0.0 9.2e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAAP01003844.1_25 - 2e-23 82.5 0.2 1e-13 51.4 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01003844.1_25 - 3e-21 75.7 0.8 2.8e-10 40.4 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AAAP01003844.1_25 - 3.7e-21 74.7 0.0 3.1e-09 36.6 0.0 3.3 3 0 0 3 3 3 2 PAS domain Response_reg PF00072.24 AAAP01003844.1_25 - 5.6e-20 71.6 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_7 PF12860.7 AAAP01003844.1_25 - 1.2e-08 35.1 0.1 0.0025 18.0 0.0 3.4 2 1 0 2 2 2 2 PAS fold PAS_11 PF14598.6 AAAP01003844.1_25 - 0.00062 19.9 0.0 0.0053 16.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain TadZ_N PF16968.5 AAAP01003844.1_25 - 0.0076 15.9 0.3 0.024 14.3 0.3 1.9 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal Response_reg PF00072.24 AAAP01003844.1_26 - 4.9e-18 65.3 0.0 5.8e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Sod_Cu PF00080.20 AAAP01003844.1_27 - 3.9e-33 114.6 2.8 4.5e-33 114.4 2.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF5642 PF18702.1 AAAP01003844.1_27 - 0.012 15.4 0.2 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) cNMP_binding PF00027.29 AAAP01003844.1_28 - 5.5e-18 64.8 0.0 9.3e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003844.1_28 - 1.1e-14 54.2 0.1 3.4e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AAAP01003844.1_28 - 0.033 14.1 0.2 0.033 14.1 0.2 2.4 3 0 0 3 3 3 0 MarR family ROK PF00480.20 AAAP01003844.1_29 - 1.2e-73 248.2 0.0 1.3e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 AAAP01003844.1_29 - 5.7e-05 22.3 0.1 0.00032 19.8 0.1 2.1 1 1 0 1 1 1 1 Glucokinase BcrAD_BadFG PF01869.20 AAAP01003844.1_29 - 0.00011 21.8 2.7 0.016 14.8 2.3 2.4 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.13 AAAP01003844.1_29 - 0.0027 17.4 0.4 0.004 16.9 0.4 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region DUF1974 PF09317.11 AAAP01003844.1_29 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) TylF PF05711.11 AAAP01003844.1_31 - 6e-10 38.8 0.0 8.9e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 AAAP01003844.1_31 - 2e-06 28.8 0.0 8e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain TPR_19 PF14559.6 AAAP01003844.1_31 - 7e-05 23.3 11.7 0.0082 16.6 2.5 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003844.1_31 - 0.023 15.3 29.3 0.082 13.6 1.8 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003844.1_31 - 0.049 14.5 35.4 0.084 13.7 2.8 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003844.1_31 - 0.079 13.6 0.1 0.079 13.6 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003844.1_31 - 0.13 12.5 0.1 5.8 7.2 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AMP-binding PF00501.28 AAAP01003844.1_32 - 8.5e-66 222.3 0.0 1.2e-65 221.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Acyltransferase PF01553.21 AAAP01003844.1_32 - 3.6e-16 59.0 0.0 8.1e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.16 AAAP01003844.1_32 - 6.8e-09 35.1 60.9 2.4e-08 33.3 35.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily AMP-binding_C PF13193.6 AAAP01003844.1_32 - 0.00022 22.2 0.1 0.00058 20.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TetR_N PF00440.23 AAAP01003844.1_33 - 1.4e-13 50.4 0.1 2.8e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AAAP01003844.1_33 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 AAAP01003844.1_33 - 0.017 15.2 0.0 0.096 12.7 0.0 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_20 PF17925.1 AAAP01003844.1_33 - 0.063 13.6 0.5 0.38 11.1 0.1 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 AAAP01003844.1_33 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF1849 PF08904.11 AAAP01003844.1_36 - 2.8e-25 89.3 0.1 3e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1849) RHS_repeat PF05593.14 AAAP01003844.1_36 - 0.035 14.6 0.7 0.55 10.8 0.1 2.4 1 1 1 2 2 2 0 RHS Repeat Urease_alpha PF00449.20 AAAP01003845.1_1 - 0.0009 19.6 0.1 0.0013 19.0 0.1 1.3 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Asn_synthase PF00733.21 AAAP01003845.1_2 - 3.8e-81 273.5 0.0 4.7e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003845.1_2 - 6.5e-36 123.0 0.0 1.7e-35 121.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003845.1_2 - 5.8e-26 91.3 0.0 2e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAAP01003845.1_2 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 AAAP01003845.1_2 - 0.054 13.0 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Glyco_trans_1_4 PF13692.6 AAAP01003845.1_3 - 2.4e-35 121.9 0.1 4e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003845.1_3 - 1.7e-34 118.9 0.0 2.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003845.1_3 - 3.8e-12 46.5 1.0 1.8e-10 41.0 0.3 2.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01003845.1_3 - 2e-10 40.9 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003845.1_3 - 1.4e-08 35.3 12.1 0.00022 21.7 0.8 3.2 2 1 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AAAP01003845.1_4 - 2.9e-09 37.5 0.0 4.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003845.1_4 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003845.1_4 - 0.009 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003845.1_4 - 0.039 13.9 0.1 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 GCV_T PF01571.21 AAAP01003845.1_5 - 4.5e-09 36.1 0.0 7.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Acetyltransf_10 PF13673.7 AAAP01003845.1_6 - 0.042 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase_3 PF13468.6 AAAP01003845.1_6 - 0.058 13.5 0.0 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain CAAP1 PF15335.6 AAAP01003845.1_7 - 1.9e-14 53.9 0.0 27 5.4 0.0 21.7 23 8 9 33 33 33 1 Caspase activity and apoptosis inhibitor 1 Pepsin-I3 PF06394.13 AAAP01003845.1_7 - 0.064 13.4 0.0 0.63 10.3 0.0 2.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain AbiEi_4 PF13338.6 AAAP01003845.1_7 - 0.22 11.7 9.4 80 3.5 0.0 9.6 8 0 0 8 8 8 0 Transcriptional regulator, AbiEi antitoxin CPSase_L_D3 PF02787.19 AAAP01003845.1_7 - 0.24 11.8 0.5 2.1e+02 2.3 0.0 6.6 5 0 0 5 5 5 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain IspA PF04279.15 AAAP01003845.1_8 - 5.2e-58 196.1 7.0 6e-58 195.9 7.0 1.0 1 0 0 1 1 1 1 Intracellular septation protein A SIS PF01380.22 AAAP01003845.1_9 - 3.4e-57 191.9 0.1 2.1e-30 105.3 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AAAP01003845.1_9 - 1.3e-22 80.4 0.4 3.4e-22 79.1 0.4 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AAAP01003845.1_9 - 3.8e-16 59.1 0.0 8.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AAAP01003845.1_9 - 0.007 15.3 0.1 0.015 14.2 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II ABC_transp_aux PF09822.9 AAAP01003845.1_9 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Hexapep PF00132.24 AAAP01003845.1_10 - 4.8e-26 89.5 18.8 3.5e-08 32.8 1.3 4.5 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AAAP01003845.1_10 - 1.2e-21 77.7 0.5 2.2e-21 76.9 0.5 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003845.1_10 - 5.6e-12 45.9 0.3 2.4e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 AAAP01003845.1_10 - 1.9e-10 40.3 17.4 1.5e-08 34.3 2.0 5.3 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 AAAP01003845.1_10 - 1.7e-05 24.6 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase CofC PF01983.16 AAAP01003845.1_10 - 0.043 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like GIT_CC PF16559.5 AAAP01003845.1_10 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CTP_transf_3 PF02348.19 AAAP01003845.1_10 - 0.19 11.6 0.0 0.64 9.9 0.0 1.8 1 1 0 1 1 1 0 Cytidylyltransferase HAD_2 PF13419.6 AAAP01003845.1_11 - 1.1e-36 126.6 0.0 1.2e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003845.1_11 - 9e-24 84.9 0.1 2.1e-21 77.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003845.1_11 - 1.4e-12 48.4 0.0 2.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003845.1_11 - 6.1e-11 42.2 0.1 1.2e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AAAP01003845.1_11 - 2.8e-07 30.6 0.0 8.9e-06 25.7 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003845.1_11 - 1.8e-05 24.6 0.0 0.85 9.3 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase NIF PF03031.18 AAAP01003845.1_11 - 0.00022 21.0 0.0 0.0072 16.1 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 AAAP01003845.1_11 - 0.038 13.8 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase PNK3P PF08645.11 AAAP01003845.1_11 - 0.21 11.3 0.0 54 3.4 0.1 3.3 3 1 1 4 4 4 0 Polynucleotide kinase 3 phosphatase EAL PF00563.20 AAAP01003845.1_12 - 8.1e-74 248.1 0.0 1.4e-73 247.3 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003845.1_12 - 1.4e-48 164.7 0.0 2.3e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AAAP01003845.1_12 - 1.6e-18 66.9 0.0 5.1e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AAAP01003845.1_12 - 2.3e-12 46.9 0.0 7.6e-12 45.2 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003845.1_12 - 3.5e-12 46.5 0.0 2.3e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAAP01003845.1_12 - 2e-09 37.7 1.1 1.2e-08 35.2 0.1 3.1 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 AAAP01003845.1_12 - 1.7e-06 27.9 0.0 8.9e-06 25.6 0.0 2.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AAAP01003845.1_12 - 2.7e-06 27.6 0.0 1e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold Hpt PF01627.23 AAAP01003845.1_12 - 1.4e-05 25.2 2.7 2.3e-05 24.6 0.6 2.6 2 0 0 2 2 2 1 Hpt domain Rrf2 PF02082.20 AAAP01003845.1_13 - 4.6e-21 75.0 0.0 6e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01003845.1_13 - 0.0001 22.1 0.1 0.00018 21.3 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 AAAP01003845.1_13 - 0.0054 16.7 0.1 0.0095 15.9 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_17 PF12728.7 AAAP01003845.1_13 - 0.0057 16.8 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAAP01003845.1_13 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 AAAP01003845.1_13 - 0.0097 16.4 0.1 0.016 15.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_42 PF06224.12 AAAP01003845.1_13 - 0.013 15.1 0.1 0.017 14.7 0.0 1.3 1 1 0 1 1 1 0 Winged helix DNA-binding domain Tn916-Xis PF09035.10 AAAP01003845.1_13 - 0.019 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Sigma70_r4 PF04545.16 AAAP01003845.1_13 - 0.022 14.3 0.3 0.04 13.4 0.3 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HrcA_DNA-bdg PF03444.15 AAAP01003845.1_13 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_23 PF13384.6 AAAP01003845.1_13 - 0.045 13.6 0.2 0.094 12.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 AAAP01003845.1_13 - 0.061 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain PuR_N PF09182.10 AAAP01003845.1_13 - 0.079 12.9 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal HTH_Tnp_ISL3 PF13542.6 AAAP01003845.1_13 - 0.12 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 B-block_TFIIIC PF04182.12 AAAP01003845.1_13 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Response_reg PF00072.24 AAAP01003845.1_14 - 6.7e-28 97.1 0.2 1.1e-27 96.4 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AAAP01003845.1_14 - 3.8e-21 75.6 0.0 6.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01003845.1_14 - 1.1e-13 51.2 0.0 2.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 HD domain Response_reg PF00072.24 AAAP01003845.1_15 - 4.7e-39 133.0 0.3 2.1e-25 89.1 0.2 2.5 2 0 0 2 2 2 2 Response regulator receiver domain PAS PF00989.25 AAAP01003845.1_15 - 3.4e-32 110.8 0.0 5.6e-15 55.3 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01003845.1_15 - 8e-32 109.6 0.0 2.9e-12 46.7 0.0 3.6 3 0 0 3 3 3 3 PAS domain HATPase_c PF02518.26 AAAP01003845.1_15 - 1.2e-31 109.5 0.0 3e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003845.1_15 - 6.8e-23 81.0 1.4 3.8e-07 30.3 0.0 4.9 4 1 0 4 4 4 3 PAS fold HisKA PF00512.25 AAAP01003845.1_15 - 1.2e-19 70.1 0.0 1.2e-19 70.1 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003845.1_15 - 3.7e-15 55.5 0.6 2.1e-07 30.8 0.0 3.0 2 0 0 2 2 2 2 PAS domain Hpt PF01627.23 AAAP01003845.1_15 - 1e-14 54.6 2.1 1e-14 54.6 2.1 2.8 2 0 0 2 2 2 1 Hpt domain PAS_7 PF12860.7 AAAP01003845.1_15 - 8.7e-10 38.8 0.1 0.0026 17.9 0.0 4.4 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.12 AAAP01003845.1_15 - 2.4e-05 24.5 0.0 0.85 9.9 0.0 3.7 3 0 0 3 3 3 2 PAS fold PAS_10 PF13596.6 AAAP01003845.1_15 - 0.049 14.2 0.0 16 6.1 0.0 3.0 3 0 0 3 3 3 0 PAS domain FIST_C PF10442.9 AAAP01003845.1_16 - 1.9e-34 118.4 0.2 4.2e-32 110.8 0.0 2.5 2 0 0 2 2 2 2 FIST C domain FIST PF08495.10 AAAP01003845.1_16 - 1.2e-33 116.6 2.1 2.3e-33 115.6 0.6 1.9 2 0 0 2 2 2 1 FIST N domain HlyD_D23 PF16576.5 AAAP01003845.1_17 - 2.1e-14 53.3 2.9 3.5e-14 52.5 2.9 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003845.1_17 - 2.3e-14 52.9 1.5 1.8e-13 50.1 0.4 2.9 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAAP01003845.1_17 - 6.3e-10 39.7 1.3 0.001 19.7 0.3 2.8 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAAP01003845.1_17 - 0.00071 19.4 0.2 0.003 17.4 0.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AAAP01003845.1_17 - 0.041 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 MM_CoA_mutase PF01642.22 AAAP01003846.1_1 - 3.5e-59 200.7 0.0 4.2e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase ADH_zinc_N PF00107.26 AAAP01003846.1_2 - 1.6e-32 112.2 0.1 3e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003846.1_2 - 4.2e-15 55.6 1.2 6.5e-15 55.0 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AAAP01003846.1_2 - 0.00011 23.3 0.0 0.00021 22.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acyl-CoA_dh_1 PF00441.24 AAAP01003846.1_3 - 2.1e-40 138.4 4.1 2.1e-40 138.4 4.1 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAAP01003846.1_3 - 3.6e-32 111.4 1.8 1.6e-31 109.3 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003846.1_3 - 2.4e-16 59.7 0.1 5.1e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAAP01003846.1_3 - 1.9e-13 50.8 0.9 4.5e-13 49.6 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HWE_HK PF07536.14 AAAP01003846.1_4 - 0.018 15.7 0.3 0.76 10.5 0.0 2.4 2 0 0 2 2 2 0 HWE histidine kinase Astacin PF01400.24 AAAP01003846.1_5 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 AAAP01003846.1_5 - 0.0026 17.6 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 AAAP01003846.1_5 - 0.021 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 BA14K PF07886.11 AAAP01003846.1_5 - 0.024 14.5 2.1 66 3.5 0.0 5.7 6 0 0 6 6 6 0 BA14K-like protein EF-hand_5 PF13202.6 AAAP01003846.1_5 - 0.029 13.9 2.0 21 4.8 0.0 5.0 5 0 0 5 5 5 0 EF hand Peptidase_M7 PF02031.16 AAAP01003846.1_5 - 0.061 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 AAAP01003846.1_5 - 0.1 11.8 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Met-zincin TauE PF01925.19 AAAP01003846.1_6 - 0.032 13.9 41.4 0.29 10.7 2.5 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Metalloenzyme PF01676.18 AAAP01003846.1_7 - 1.1e-78 264.0 0.0 1.3e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AAAP01003846.1_7 - 2.2e-71 239.8 0.0 3.2e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Peptidase_M23 PF01551.22 AAAP01003846.1_8 - 1.4e-20 73.3 0.0 2.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M23 KASH_CCD PF14662.6 AAAP01003846.1_8 - 0.0076 16.1 3.3 0.0076 16.1 3.3 3.3 2 1 0 3 3 3 2 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 AAAP01003846.1_8 - 0.93 9.5 10.0 4 7.5 1.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S41 PF03572.18 AAAP01003846.1_9 - 8.3e-56 188.1 0.0 1.2e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 AAAP01003846.1_9 - 7.4e-13 48.1 0.1 2.3e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 AAAP01003846.1_9 - 1e-12 48.2 0.1 2e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AAAP01003846.1_9 - 5.6e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain TSP_NTD PF17804.1 AAAP01003846.1_9 - 9.9e-05 22.7 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Tail specific protease N-terminal domain Polysacc_deac_2 PF04748.13 AAAP01003846.1_10 - 8.8e-35 119.8 0.0 1.3e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase NUDIX PF00293.28 AAAP01003846.1_11 - 4.2e-23 81.8 0.1 5.2e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Lipase_GDSL_2 PF13472.6 AAAP01003846.1_12 - 2.4e-08 34.6 0.0 5e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M48 PF01435.18 AAAP01003846.1_13 - 8.5e-33 113.8 0.0 1.4e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 LysM PF01476.20 AAAP01003846.1_13 - 0.0015 18.5 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF3071 PF11268.8 AAAP01003846.1_13 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) TP_methylase PF00590.20 AAAP01003846.1_14 - 8.2e-36 123.9 0.5 1.5e-35 123.0 0.5 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiG_C PF01890.16 AAAP01003846.1_14 - 1.9e-29 102.6 1.9 3.5e-29 101.7 1.9 1.5 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus CbiG_N PF11760.8 AAAP01003846.1_14 - 2.8e-23 81.7 0.0 7.6e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis G N-terminal CbiG_mid PF11761.8 AAAP01003846.1_14 - 0.00021 21.4 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 Cobalamin biosynthesis central region TP_methylase PF00590.20 AAAP01003846.1_15 - 6.7e-46 156.9 1.3 7.5e-46 156.7 1.3 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UTRA PF07702.13 AAAP01003846.1_15 - 0.18 11.6 0.6 4.1 7.3 0.0 2.6 2 1 0 2 2 2 0 UTRA domain DUF4219 PF13961.6 AAAP01003846.1_15 - 0.25 11.1 0.1 0.45 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TP_methylase PF00590.20 AAAP01003846.1_16 - 1.2e-17 64.6 0.3 2.7e-17 63.4 0.2 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_25 PF13649.6 AAAP01003846.1_16 - 0.00032 21.4 0.0 0.00065 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AAAP01003846.1_16 - 0.0046 16.6 0.0 0.0092 15.6 0.0 1.4 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_11 PF08241.12 AAAP01003846.1_16 - 0.03 14.9 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003846.1_16 - 0.098 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain BcsB PF03170.13 AAAP01003846.1_16 - 0.15 10.4 0.1 0.22 9.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit CbiC PF02570.15 AAAP01003846.1_17 - 1.1e-66 224.2 2.5 1.3e-66 224.0 2.5 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase Cons_hypoth95 PF03602.15 AAAP01003846.1_17 - 0.0082 15.8 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CbiX PF01903.17 AAAP01003846.1_18 - 5.6e-48 161.7 0.0 4.9e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 AAAP01003846.1_18 - 2.1e-06 27.3 0.0 0.034 13.5 0.0 2.3 2 0 0 2 2 2 2 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 AAAP01003846.1_18 - 6.9e-05 22.1 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 2 Ferrochelatase SelP_N PF04592.14 AAAP01003846.1_18 - 0.25 10.7 12.4 0.36 10.2 12.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CobD_Cbib PF03186.13 AAAP01003846.1_19 - 1.7e-94 316.1 0.5 2e-94 315.9 0.5 1.0 1 0 0 1 1 1 1 CobD/Cbib protein FA_desaturase PF00487.24 AAAP01003846.1_19 - 0.026 14.4 0.7 0.026 14.4 0.7 2.2 1 1 1 2 2 2 0 Fatty acid desaturase GATase_3 PF07685.14 AAAP01003846.1_20 - 1.5e-14 54.1 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF5568 PF17724.1 AAAP01003846.1_20 - 0.25 11.2 0.4 0.31 10.8 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5568) SBP_bac_5 PF00496.22 AAAP01003847.1_1 - 4.3e-73 246.4 0.4 5.4e-73 246.1 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_L35p PF01632.19 AAAP01003847.1_2 - 1.9e-21 76.3 8.4 2e-21 76.2 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 AAAP01003847.1_3 - 4.2e-50 168.3 3.8 4.8e-50 168.1 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 DDE_Tnp_IS66 PF03050.14 AAAP01003847.1_3 - 0.0055 16.2 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 Transposase IS66 family Phe_tRNA-synt_N PF02912.18 AAAP01003847.1_4 - 4.8e-08 32.8 0.0 2.3e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA-synt_2d PF01409.20 AAAP01003847.1_5 - 4.4e-103 344.0 0.0 5e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AAAP01003847.1_5 - 1.8e-08 34.2 0.3 9.3e-08 31.9 1.1 1.7 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 AAAP01003847.1_5 - 0.047 13.1 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain DUF3008 PF11450.8 AAAP01003847.1_5 - 3.1 8.0 5.8 4.6 7.5 5.0 1.6 1 1 0 1 1 1 0 Protein of unknwon function (DUF3008) B3_4 PF03483.17 AAAP01003847.1_6 - 9.4e-61 204.5 0.0 1.4e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 AAAP01003847.1_6 - 1.6e-43 148.6 0.0 2.5e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AAAP01003847.1_6 - 2.4e-23 82.4 0.1 4.6e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AAAP01003847.1_6 - 2.4e-23 82.0 0.6 2.1e-22 79.1 0.1 2.6 3 0 0 3 3 3 1 Putative tRNA binding domain B5 PF03484.15 AAAP01003847.1_6 - 2.9e-18 65.9 0.1 2.4e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF4908 PF16252.5 AAAP01003847.1_6 - 0.023 14.2 1.7 0.086 12.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) His_Phos_1 PF00300.22 AAAP01003847.1_7 - 1.6e-42 145.5 0.1 1.9e-42 145.2 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4648 PF15505.6 AAAP01003847.1_7 - 0.06 14.2 0.0 18 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) MarR_2 PF12802.7 AAAP01003847.1_8 - 7e-12 45.1 1.2 1.2e-11 44.3 0.2 1.8 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAAP01003847.1_8 - 2.6e-08 34.2 0.0 3.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AAAP01003847.1_8 - 2.9e-08 33.5 0.0 5.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AAAP01003847.1_8 - 0.0014 18.6 0.2 0.0039 17.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 AAAP01003847.1_8 - 0.033 14.0 1.7 0.043 13.6 0.2 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain AbiEi_4 PF13338.6 AAAP01003847.1_8 - 0.078 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin DLH PF01738.18 AAAP01003847.1_9 - 4.7e-68 229.0 0.0 5.6e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAAP01003847.1_9 - 4.9e-06 26.2 0.3 0.0053 16.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AAAP01003847.1_9 - 0.00023 21.0 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 AAAP01003847.1_9 - 0.00069 18.7 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 AAAP01003847.1_9 - 0.005 16.1 0.0 1.5 8.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003847.1_9 - 0.0087 15.7 0.0 0.094 12.3 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 AAAP01003847.1_9 - 0.012 15.5 0.0 1.4 8.7 0.1 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 AAAP01003847.1_9 - 0.029 14.0 1.0 0.071 12.7 0.9 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 AAAP01003847.1_9 - 0.043 13.7 2.2 0.24 11.2 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AAAP01003847.1_9 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme YGGT PF02325.17 AAAP01003847.1_10 - 2.3e-16 59.9 9.0 3.1e-16 59.6 9.0 1.2 1 0 0 1 1 1 1 YGGT family DUF167 PF02594.16 AAAP01003847.1_11 - 6.8e-24 83.8 0.2 8e-24 83.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Nas2_N PF18265.1 AAAP01003847.1_11 - 0.038 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Nas2 N_terminal domain THF_DHG_CYH_C PF02882.19 AAAP01003847.1_12 - 1.3e-66 222.8 2.7 1.3e-66 222.8 2.7 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AAAP01003847.1_12 - 4.1e-39 133.4 0.0 6.2e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 AAAP01003847.1_12 - 0.014 14.4 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NnrU PF07298.11 AAAP01003847.1_13 - 2.3e-58 197.2 12.6 2.5e-58 197.0 12.6 1.0 1 0 0 1 1 1 1 NnrU protein PmbA_TldD PF01523.16 AAAP01003847.1_14 - 2.7e-26 93.0 1.2 3.3e-26 92.8 1.2 1.0 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 AAAP01003847.1_15 - 9.1e-24 84.8 0.0 1.5e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Putative modulator of DNA gyrase 2-Hacid_dh_C PF02826.19 AAAP01003847.1_16 - 5.3e-59 198.6 0.1 9.5e-59 197.7 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01003847.1_16 - 3.7e-32 110.8 0.0 4.5e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AAAP01003847.1_16 - 1.4e-05 25.3 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01003847.1_16 - 0.0027 18.2 0.0 0.02 15.5 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 AAAP01003847.1_16 - 0.0037 16.9 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 AAAP01003847.1_16 - 0.041 14.7 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SH3_4 PF06347.13 AAAP01003847.1_17 - 8.1e-25 86.4 0.7 3.5e-16 58.8 0.2 2.2 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_3 PF08239.11 AAAP01003847.1_17 - 2.2e-06 27.8 0.1 0.0012 19.0 0.6 2.8 2 1 0 2 2 2 2 Bacterial SH3 domain DHC PF09626.10 AAAP01003847.1_18 - 2e-38 131.9 0.0 2.3e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Dihaem cytochrome c Cytochrome_C7 PF14522.6 AAAP01003847.1_18 - 0.0016 18.4 0.3 0.98 9.5 0.1 2.2 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrom_NNT PF03264.14 AAAP01003847.1_18 - 0.0018 18.0 0.3 0.044 13.5 0.1 2.1 2 0 0 2 2 2 1 NapC/NirT cytochrome c family, N-terminal region Paired_CXXCH_1 PF09699.10 AAAP01003847.1_18 - 0.035 13.8 1.3 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_C PF00034.21 AAAP01003847.1_18 - 0.13 13.4 1.4 5.6 8.2 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003847.1_18 - 0.22 11.9 2.5 10 6.5 0.0 2.5 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1924 PF09086.11 AAAP01003847.1_19 - 4.6e-38 129.5 0.2 6.2e-38 129.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1924) Ni_hydr_CYTB PF01292.20 AAAP01003847.1_19 - 0.0021 17.7 17.1 0.0021 17.7 17.1 2.0 2 1 0 2 2 2 1 Prokaryotic cytochrome b561 CCP_MauG PF03150.14 AAAP01003847.1_19 - 0.012 16.3 0.1 0.018 15.7 0.1 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Peptidase_U4 PF03419.13 AAAP01003847.1_19 - 0.012 14.9 3.3 0.022 14.0 3.2 1.5 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF4079 PF13301.6 AAAP01003847.1_19 - 2.3 8.4 14.2 0.28 11.3 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4658 PF15555.6 AAAP01003847.1_19 - 3 8.0 7.8 0.42 10.7 0.5 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4658) DUF4405 PF14358.6 AAAP01003847.1_19 - 8.1 7.1 13.5 3.2 8.4 3.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Peptidase_M73 PF12389.8 AAAP01003847.1_20 - 0.14 11.9 0.1 0.14 11.9 0.1 1.0 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase PepSY PF03413.19 AAAP01003847.1_21 - 2.3e-07 31.3 0.0 2.7e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AAAP01003847.1_21 - 0.0009 19.2 0.0 0.0044 17.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain AbiEi_4 PF13338.6 AAAP01003847.1_21 - 0.048 13.8 1.1 0.081 13.1 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Response_reg PF00072.24 AAAP01003847.1_22 - 6.2e-26 90.8 0.0 1.3e-25 89.8 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003847.1_22 - 1.2e-21 76.5 0.1 3.7e-21 75.0 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAAP01003847.1_22 - 0.064 13.1 0.0 0.2 11.6 0.0 1.8 1 1 0 1 1 1 0 MarR family HATPase_c PF02518.26 AAAP01003847.1_23 - 1.6e-07 31.8 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003847.1_23 - 0.0071 16.3 0.3 0.081 12.9 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain 2CSK_N PF08521.10 AAAP01003847.1_23 - 0.011 15.8 0.9 0.022 14.8 0.9 1.5 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal HAMP PF00672.25 AAAP01003847.1_23 - 0.018 15.4 2.4 0.051 14.0 0.0 3.0 3 0 0 3 3 3 0 HAMP domain Ric8 PF10165.9 AAAP01003847.1_23 - 0.19 10.8 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn HisKA PF00512.25 AAAP01003847.1_23 - 2 8.5 5.2 0.37 10.9 0.2 2.4 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain SpoIIE PF07228.12 AAAP01003847.1_24 - 4.2e-25 88.8 0.0 8.5e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HAMP PF00672.25 AAAP01003847.1_24 - 0.0087 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 HAMP domain SBP_bac_3 PF00497.20 AAAP01003847.1_25 - 4.5e-18 65.5 0.0 5.3e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF1566 PF07603.11 AAAP01003847.1_26 - 8.7e-38 129.2 0.0 3.2e-19 69.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1566) CHAT PF12770.7 AAAP01003847.1_27 - 6e-51 173.6 0.0 6e-51 173.6 0.0 2.5 3 0 0 3 3 3 1 CHAT domain TPR_12 PF13424.6 AAAP01003847.1_27 - 2.3e-15 56.7 25.3 1e-06 28.9 1.8 6.0 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003847.1_27 - 7.8e-10 38.6 3.8 7.8e-10 38.6 3.8 3.0 1 1 2 3 3 3 2 MalT-like TPR region TPR_1 PF00515.28 AAAP01003847.1_27 - 2.7e-06 26.9 11.7 0.0083 15.9 1.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003847.1_27 - 1.6e-05 24.7 15.2 0.04 14.1 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003847.1_27 - 1.8e-05 24.5 32.3 0.035 14.2 1.3 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003847.1_27 - 0.0036 17.1 27.9 0.093 12.6 0.4 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF3856 PF12968.7 AAAP01003847.1_27 - 0.011 15.9 5.1 1.2 9.2 0.0 3.8 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 AAAP01003847.1_27 - 0.15 11.7 9.6 0.46 10.2 2.0 4.8 2 1 2 4 4 4 0 TPR repeat PAS_3 PF08447.12 AAAP01003847.1_28 - 3.8e-11 43.1 0.0 6.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003847.1_28 - 3.8e-09 36.7 0.0 5.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003847.1_28 - 3.8e-08 33.3 0.0 5.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003847.1_28 - 3e-05 24.2 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003847.1_28 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain HAMP PF00672.25 AAAP01003847.1_29 - 1.6e-06 28.3 3.1 0.00049 20.4 0.4 2.5 2 0 0 2 2 2 2 HAMP domain Laminin_I PF06008.14 AAAP01003847.1_29 - 0.019 14.7 0.6 0.034 13.8 0.6 1.4 1 0 0 1 1 1 0 Laminin Domain I ArsP_1 PF03773.13 AAAP01003847.1_29 - 0.075 12.2 4.4 0.12 11.5 4.4 1.2 1 0 0 1 1 1 0 Predicted permease Phage_Gp19 PF09355.10 AAAP01003847.1_29 - 0.2 12.1 2.4 0.58 10.6 0.3 2.5 2 1 1 3 3 3 0 Phage protein Gp19/Gp15/Gp42 DUF2157 PF09925.9 AAAP01003847.1_29 - 3.8 7.3 11.2 6.5 6.5 11.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF4282 PF14110.6 AAAP01003847.1_29 - 5.6 7.8 7.7 11 6.9 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) MaoC_dehydratas PF01575.19 AAAP01003848.1_1 - 2e-14 53.2 0.5 4.1e-07 29.6 0.1 2.5 2 1 0 2 2 2 2 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01003848.1_1 - 0.0034 17.5 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase HpcH_HpaI PF03328.14 AAAP01003848.1_2 - 9.2e-50 168.8 0.0 1.5e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01003848.1_2 - 9.1e-09 34.9 0.1 0.0026 17.0 0.0 2.3 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.18 AAAP01003848.1_2 - 0.00035 19.8 0.0 0.00057 19.1 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Phos_pyr_kin PF08543.12 AAAP01003848.1_3 - 1.3e-19 70.6 0.0 1.7e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AAAP01003848.1_3 - 3.5e-09 36.4 0.0 8.7e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase LysE PF01810.18 AAAP01003848.1_4 - 6.5e-21 74.7 12.9 7.9e-21 74.4 12.9 1.0 1 0 0 1 1 1 1 LysE type translocator CopD PF05425.13 AAAP01003848.1_4 - 0.0032 17.8 4.4 0.0032 17.8 4.4 2.4 2 0 0 2 2 2 1 Copper resistance protein D Acetyltransf_1 PF00583.25 AAAP01003848.1_5 - 3.6e-11 43.3 0.0 4.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003848.1_5 - 3.6e-10 40.1 0.0 5.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003848.1_5 - 6.3e-09 35.8 0.0 7.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003848.1_5 - 0.00018 21.4 0.0 0.00058 19.8 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 AAAP01003848.1_5 - 0.19 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Polysacc_deac_1 PF01522.21 AAAP01003848.1_6 - 1.4e-25 89.6 0.1 2e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 AAAP01003848.1_6 - 0.075 12.2 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 GST_N_3 PF13417.6 AAAP01003848.1_7 - 2.7e-18 66.2 0.0 5.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003848.1_7 - 1.3e-12 47.8 0.0 3.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01003848.1_7 - 9.3e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003848.1_7 - 3.2e-07 30.3 1.4 8.1e-07 29.0 1.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AAAP01003848.1_7 - 5.6e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AAAP01003848.1_7 - 0.00015 21.9 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AAAP01003848.1_7 - 0.051 13.9 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein DUF4743 PF15916.5 AAAP01003848.1_8 - 4.1e-33 113.9 0.0 5.8e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) HSP20 PF00011.21 AAAP01003848.1_9 - 2.8e-16 59.5 0.0 4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AAAP01003848.1_9 - 0.036 13.6 0.0 0.08 12.5 0.0 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA DUF1150 PF06620.11 AAAP01003848.1_10 - 1.3e-10 41.2 0.1 1.9e-08 34.3 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1150) PTS_EIIA_2 PF00359.22 AAAP01003848.1_11 - 2.3e-35 121.6 0.0 2.6e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Sigma54_DBD PF04552.13 AAAP01003848.1_12 - 2e-68 229.1 0.7 3e-68 228.6 0.7 1.3 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 AAAP01003848.1_12 - 6.3e-51 172.8 0.0 1.2e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 AAAP01003848.1_12 - 2.6e-19 68.8 7.2 6.1e-19 67.6 7.2 1.7 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) Arg_repressor PF01316.21 AAAP01003848.1_12 - 0.0085 15.8 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_23 PF13384.6 AAAP01003848.1_12 - 0.058 13.2 0.1 22 5.0 0.0 3.5 3 0 0 3 3 3 0 Homeodomain-like domain Sigma70_r3 PF04539.16 AAAP01003848.1_12 - 0.099 12.7 0.1 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_38 PF13936.6 AAAP01003848.1_12 - 0.14 11.9 0.2 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_tran PF00005.27 AAAP01003848.1_13 - 3.3e-33 115.1 0.0 4.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003848.1_13 - 2.7e-07 30.7 1.2 0.011 15.6 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAAP01003848.1_13 - 1.7e-05 24.6 0.2 3.2e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAAP01003848.1_13 - 0.009 16.5 0.1 0.012 16.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003848.1_13 - 0.012 15.0 0.1 3.9 6.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003848.1_13 - 0.045 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 AAAP01003848.1_13 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain OstA PF03968.14 AAAP01003848.1_14 - 6.6e-13 48.8 0.1 2.3e-06 27.8 0.0 2.7 2 1 1 3 3 3 2 OstA-like protein LptC PF06835.13 AAAP01003848.1_14 - 0.0088 15.6 0.0 0.98 9.0 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide-assembly, LptC-related OstA_2 PF13100.6 AAAP01003848.1_14 - 0.079 12.5 0.1 16 5.1 0.0 2.3 2 1 0 2 2 2 0 OstA-like protein LptC PF06835.13 AAAP01003848.1_15 - 1.3e-11 44.4 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related SIS PF01380.22 AAAP01003848.1_16 - 1.6e-29 102.4 0.0 2.8e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 AAAP01003848.1_16 - 5.4e-17 62.0 0.0 4.7e-10 39.7 0.0 3.4 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 AAAP01003848.1_16 - 0.00045 20.3 0.4 0.038 14.0 0.0 2.6 1 1 1 2 2 2 2 SIS domain DNA_pol_A_exo1 PF01612.20 AAAP01003848.1_17 - 3e-33 115.0 0.0 3.6e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease RNase_H_2 PF13482.6 AAAP01003848.1_17 - 0.00041 20.4 0.0 0.0025 17.9 0.0 1.9 1 1 0 1 1 1 1 RNase_H superfamily RNase_T PF00929.24 AAAP01003848.1_17 - 0.0065 17.0 0.0 1.6 9.3 0.0 2.2 1 1 0 2 2 2 2 Exonuclease NAD_binding_10 PF13460.6 AAAP01003848.1_18 - 2.8e-21 76.2 5.8 1.4e-19 70.7 5.7 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 AAAP01003848.1_18 - 8.6e-19 67.9 0.0 2.6e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AAAP01003848.1_18 - 9.1e-19 67.9 2.3 3.5e-14 52.9 4.0 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 AAAP01003848.1_18 - 1.1e-16 60.7 0.1 9.2e-13 47.8 0.1 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003848.1_18 - 2.4e-14 53.1 0.0 8.2e-12 44.8 0.0 3.0 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 AAAP01003848.1_18 - 9.1e-06 25.3 1.3 1.8e-05 24.3 1.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 AAAP01003848.1_18 - 3.2e-05 24.2 0.6 6.1e-05 23.3 0.4 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 AAAP01003848.1_18 - 0.00039 19.7 0.1 0.027 13.7 0.0 2.6 1 1 1 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AAAP01003848.1_18 - 0.00098 18.6 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 AAAP01003848.1_18 - 0.0014 18.5 0.9 0.0024 17.8 0.9 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 AAAP01003848.1_18 - 0.018 14.6 4.1 0.068 12.7 3.4 2.1 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Glyco_trans_4_4 PF13579.6 AAAP01003848.1_18 - 0.029 14.8 2.3 0.046 14.2 2.3 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4808 PF16066.5 AAAP01003848.1_18 - 0.074 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Polysacc_synt_2 PF02719.15 AAAP01003848.1_18 - 0.16 11.1 1.8 1.1 8.4 2.1 2.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein NTP_transf_3 PF12804.7 AAAP01003848.1_19 - 0.025 14.9 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 MobA-like NTP transferase domain HTH_31 PF13560.6 AAAP01003848.1_19 - 0.026 14.9 2.9 0.035 14.4 2.9 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAAP01003848.1_19 - 0.027 14.3 1.4 0.12 12.3 1.4 2.1 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TilS PF09179.11 AAAP01003848.1_19 - 0.13 12.8 3.5 1.1 9.8 0.3 2.1 2 0 0 2 2 2 0 TilS substrate binding domain Phage_integrase PF00589.22 AAAP01003848.1_20 - 6.7e-41 139.9 0.0 8.5e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAAP01003848.1_20 - 1.4e-17 63.7 0.0 5.5e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AAAP01003848.1_20 - 2.2e-07 31.3 0.0 4.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Gram_pos_anchor PF00746.21 AAAP01003848.1_22 - 2.6 8.1 4.8 3.1 7.8 4.8 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SKI PF01202.22 AAAP01003848.1_23 - 2.3e-40 138.3 0.0 2.9e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AAAP01003848.1_23 - 8.7e-06 26.3 0.0 2.6e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003848.1_23 - 1.9e-05 24.8 0.0 3.8e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AAAP01003848.1_23 - 0.00025 21.3 0.1 0.0013 18.9 0.1 1.8 1 1 1 2 2 2 1 Cytidylate kinase-like family TsaE PF02367.17 AAAP01003848.1_23 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AAAP01003848.1_23 - 0.018 15.4 0.1 0.021 15.2 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 AAAP01003848.1_23 - 0.067 12.9 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase Asp_protease_2 PF13650.6 AAAP01003848.1_23 - 0.14 12.8 0.0 0.31 11.7 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease AAA_22 PF13401.6 AAAP01003848.1_23 - 0.16 12.2 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DHQ_synthase PF01761.20 AAAP01003848.1_24 - 4.8e-102 340.6 0.1 5.9e-102 340.3 0.1 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AAAP01003848.1_24 - 3.7e-19 69.4 0.6 1.3e-17 64.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AAAP01003848.1_24 - 9.5e-16 57.6 3.3 3.1e-13 49.3 0.3 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF21 PF01595.20 AAAP01003848.1_25 - 6.8e-39 133.4 3.7 9.7e-39 132.9 3.7 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AAAP01003848.1_25 - 3.4e-20 71.9 0.0 8.5e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AAAP01003848.1_25 - 3.6e-17 62.6 3.8 2.7e-07 30.9 0.1 3.8 4 0 0 4 4 4 2 CBS domain PhoH PF02562.16 AAAP01003848.1_26 - 8.4e-78 260.5 0.0 9.6e-78 260.3 0.0 1.0 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AAAP01003848.1_26 - 1.3e-09 38.1 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAAP01003848.1_26 - 5e-07 30.1 0.1 5.3e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003848.1_26 - 0.00044 20.5 0.1 0.0017 18.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAAP01003848.1_26 - 0.00061 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD-helicase PF00580.21 AAAP01003848.1_26 - 0.00068 19.2 0.1 0.095 12.2 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 AAAP01003848.1_26 - 0.00078 19.3 0.0 0.0078 16.0 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 AAAP01003848.1_26 - 0.0021 17.7 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AAAP01003848.1_26 - 0.018 14.3 0.0 0.051 12.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.12 AAAP01003848.1_26 - 0.019 14.6 0.0 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 AAAP01003848.1_26 - 0.038 13.8 0.0 8.7 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AAAP01003848.1_26 - 0.042 14.2 0.0 0.083 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AAAP01003848.1_26 - 0.13 12.7 0.4 0.23 11.9 0.1 1.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 AAAP01003848.1_26 - 0.14 11.9 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase TP_methylase PF00590.20 AAAP01003849.1_1 - 3.5e-05 23.8 0.1 4.2e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ion_trans PF00520.31 AAAP01003849.1_2 - 4.7e-29 101.3 6.7 5.4e-29 101.1 6.7 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AAAP01003849.1_2 - 2.4e-14 53.0 2.5 2.4e-14 53.0 2.5 1.9 2 0 0 2 2 2 1 Ion channel Metal_resist PF13801.6 AAAP01003849.1_3 - 0.054 13.7 0.8 0.15 12.2 0.8 1.7 1 0 0 1 1 1 0 Heavy-metal resistance GGDEF PF00990.21 AAAP01003849.1_5 - 1.1e-45 155.3 0.0 1.9e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AAAP01003849.1_5 - 0.08 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cache domain CMD PF02627.20 AAAP01003849.1_6 - 1.4e-19 69.9 0.3 2e-19 69.4 0.3 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF533 PF04391.12 AAAP01003849.1_6 - 0.45 10.1 5.7 0.65 9.5 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF533) Sulf_transp PF04143.14 AAAP01003849.1_7 - 4.9e-08 32.9 21.1 1.2e-07 31.6 21.1 1.6 1 1 0 1 1 1 1 Sulphur transport VacA2 PF03077.14 AAAP01003849.1_7 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative vacuolating cytotoxin cNMP_binding PF00027.29 AAAP01003849.1_9 - 6.6e-14 51.7 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003849.1_9 - 4.1e-09 36.3 0.1 9.8e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003849.1_9 - 9.5e-06 25.2 0.0 3e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family DUF1670 PF07900.11 AAAP01003849.1_9 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1670) MarR_2 PF12802.7 AAAP01003849.1_9 - 0.0088 15.9 0.2 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 MarR family DUF2857 PF11198.8 AAAP01003849.1_9 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Fer4_18 PF13746.6 AAAP01003849.1_10 - 7.6e-39 132.4 7.3 3.1e-38 130.5 7.3 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AAAP01003849.1_10 - 1.6e-29 102.5 0.0 2.2e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_9 PF13187.6 AAAP01003849.1_10 - 4e-09 36.5 4.7 6.5e-05 23.0 0.9 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003849.1_10 - 3e-08 34.1 5.4 0.00083 19.9 1.6 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003849.1_10 - 3.6e-07 30.5 3.5 0.018 15.5 0.1 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003849.1_10 - 5e-07 30.2 4.8 0.0014 19.1 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_5 PF12801.7 AAAP01003849.1_10 - 8.7e-07 28.8 7.2 8.7e-07 28.8 7.2 3.6 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003849.1_10 - 5.3e-05 22.9 24.2 0.0037 17.0 4.2 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003849.1_10 - 0.004 17.2 12.1 0.004 17.2 12.1 2.8 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003849.1_10 - 0.0089 16.1 13.6 0.012 15.7 3.2 3.3 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003849.1_10 - 0.012 16.0 18.3 0.098 13.2 2.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAAP01003849.1_10 - 0.14 13.0 9.4 1.1 10.1 2.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003849.1_10 - 0.16 12.9 16.5 0.76 10.7 3.5 2.9 1 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 AAAP01003849.1_10 - 0.26 12.3 24.4 0.41 11.7 5.2 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003849.1_10 - 0.28 11.3 23.0 0.17 12.0 3.4 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003849.1_10 - 0.8 9.9 18.4 1.1 9.4 4.1 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003849.1_10 - 2 9.0 13.7 2.8 8.5 1.1 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF2892 PF11127.8 AAAP01003849.1_11 - 7.7e-24 83.5 4.4 8.3e-24 83.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) HTH_Crp_2 PF13545.6 AAAP01003849.1_12 - 7.5e-13 48.3 0.5 1.3e-12 47.5 0.5 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003849.1_12 - 6.7e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Crp PF00325.20 AAAP01003849.1_12 - 3.2e-07 29.9 0.0 6.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 AAAP01003849.1_12 - 4.5e-05 23.3 0.4 9.8e-05 22.2 0.4 1.6 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 AAAP01003849.1_12 - 0.042 13.9 2.7 0.059 13.4 0.3 2.3 3 0 0 3 3 3 0 Winged helix-turn helix TrmB PF01978.19 AAAP01003849.1_12 - 0.096 12.6 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AAAP01003849.1_12 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DUF1670 PF07900.11 AAAP01003849.1_12 - 0.12 11.8 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) HTH_24 PF13412.6 AAAP01003849.1_12 - 0.14 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AAAP01003849.1_12 - 0.26 11.1 3.0 0.21 11.4 0.3 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AAAP01003849.1_13 - 0.0034 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 AAAP01003849.1_13 - 0.0083 15.8 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AAAP01003849.1_13 - 0.02 14.8 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 AAAP01003849.1_13 - 0.065 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4167 PF13763.6 AAAP01003849.1_14 - 0.058 13.5 0.1 0.086 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) HATPase_c PF02518.26 AAAP01003849.1_16 - 8.7e-24 84.2 0.0 1.6e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003849.1_16 - 1.4e-15 57.1 0.1 4.4e-15 55.5 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01003849.1_16 - 0.00019 21.2 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003849.1_16 - 0.0049 16.8 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain B12-binding PF02310.19 AAAP01003849.1_17 - 2.9e-17 62.8 0.0 5.7e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AAAP01003849.1_17 - 1.2e-07 32.1 0.1 1.7e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 B12 binding domain EAL PF00563.20 AAAP01003849.1_18 - 1.1e-69 234.6 0.0 2e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003849.1_18 - 4.6e-11 42.7 0.0 7.6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AAAP01003849.1_18 - 0.0024 18.1 0.0 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003849.1_18 - 0.0071 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain Response_reg PF00072.24 AAAP01003849.1_19 - 3.1e-21 75.6 0.0 5.5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003849.1_19 - 4.9e-19 68.2 0.1 8e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal RuvA_N PF01330.21 AAAP01003849.1_19 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 RuvA N terminal domain Response_reg PF00072.24 AAAP01003849.1_20 - 6.1e-17 61.8 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 AAAP01003849.1_20 - 5.4e-07 29.8 1.4 5.4e-07 29.8 1.4 2.3 2 1 0 2 2 2 1 Hpt domain Peptidase_C4 PF00863.19 AAAP01003849.1_20 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 Hemerythrin PF01814.23 AAAP01003849.1_22 - 1.1e-09 39.1 4.2 1.4e-09 38.7 4.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DnaB PF00772.21 AAAP01003849.1_22 - 0.15 12.1 0.3 20 5.3 0.0 2.8 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain MerR_1 PF13411.6 AAAP01003849.1_23 - 4e-10 39.6 0.0 8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein B12-binding PF02310.19 AAAP01003849.1_23 - 9.1e-10 38.6 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AAAP01003849.1_23 - 1.2e-06 28.9 0.0 3.6e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 B12 binding domain MerR PF00376.23 AAAP01003849.1_23 - 2.3e-06 27.3 0.2 4.7e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 MerR family regulatory protein Heme_oxygenase PF01126.20 AAAP01003849.1_26 - 7.1e-10 39.0 0.0 3.9e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Heme oxygenase RepB PF07506.11 AAAP01003849.1_27 - 4.8e-56 189.8 0.4 6.3e-56 189.4 0.4 1.2 1 0 0 1 1 1 1 RepB plasmid partitioning protein ParBc PF02195.18 AAAP01003849.1_27 - 2.4e-08 34.1 0.0 5.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_23 PF13384.6 AAAP01003849.1_27 - 0.049 13.4 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Lectin_N PF03954.14 AAAP01003849.1_27 - 0.12 12.1 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain RepB PF07506.11 AAAP01003849.1_28 - 1.2e-30 107.0 3.5 1.6e-30 106.6 3.5 1.1 1 0 0 1 1 1 1 RepB plasmid partitioning protein ParBc PF02195.18 AAAP01003849.1_28 - 2.3e-10 40.6 0.0 9.1e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain Lectin_like PF18560.1 AAAP01003849.1_28 - 0.09 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Lectin like domain Resolvase PF00239.21 AAAP01003849.1_29 - 8.3e-22 77.9 0.4 1.4e-21 77.1 0.4 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 AAAP01003849.1_29 - 2.9e-18 66.2 0.0 6e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Recombinase OAD_gamma PF04277.13 AAAP01003849.1_32 - 0.01 16.4 0.6 0.013 16.1 0.6 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TniQ PF06527.11 AAAP01003849.1_33 - 1.1e-18 68.3 0.7 4.9e-18 66.2 0.3 2.3 2 0 0 2 2 2 1 TniQ HTH_17 PF12728.7 AAAP01003849.1_33 - 1.6e-12 47.4 0.3 0.0039 17.4 0.0 4.2 4 0 0 4 4 4 3 Helix-turn-helix domain AbiEi_4 PF13338.6 AAAP01003849.1_33 - 0.00024 21.2 6.6 3.4 7.9 0.1 4.5 4 0 0 4 4 4 3 Transcriptional regulator, AbiEi antitoxin HTH_IclR PF09339.10 AAAP01003849.1_33 - 0.051 13.4 0.4 0.051 13.4 0.4 3.5 4 0 0 4 4 4 0 IclR helix-turn-helix domain DUF134 PF02001.16 AAAP01003849.1_33 - 0.12 12.9 0.2 21 5.8 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function DUF134 DUF746 PF05344.11 AAAP01003849.1_33 - 0.13 12.1 0.1 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Tn916-Xis PF09035.10 AAAP01003849.1_33 - 0.16 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Zn_Tnp_IS1595 PF12760.7 AAAP01003849.1_33 - 5.9 6.9 8.5 13 5.8 3.4 2.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TniB PF05621.11 AAAP01003849.1_34 - 0.00013 21.5 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein CBS PF00571.28 AAAP01003850.1_1 - 2.4e-23 82.3 1.9 2.1e-09 37.7 0.3 3.1 3 0 0 3 3 3 3 CBS domain IF3_N PF05198.16 AAAP01003850.1_1 - 0.15 12.4 0.1 26 5.2 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Hpt PF01627.23 AAAP01003850.1_2 - 7.4e-06 26.1 0.1 1e-05 25.7 0.1 1.2 1 0 0 1 1 1 1 Hpt domain Mst1_SARAH PF11629.8 AAAP01003850.1_2 - 0.16 12.1 0.9 0.36 10.9 0.7 1.7 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Response_reg PF00072.24 AAAP01003850.1_3 - 1e-09 38.5 0.1 1.2e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Fer2_2 PF01799.20 AAAP01003850.1_3 - 0.2 11.7 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 [2Fe-2S] binding domain DLH PF01738.18 AAAP01003850.1_4 - 5.1e-16 58.9 0.0 1.1e-15 57.8 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AAAP01003850.1_4 - 1.1e-09 38.0 0.0 0.0013 18.3 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 AAAP01003850.1_4 - 0.0023 16.7 0.0 0.025 13.3 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 AAAP01003850.1_4 - 0.0025 17.7 0.1 0.43 10.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003850.1_4 - 0.0038 17.9 7.4 0.051 14.2 2.7 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01003850.1_4 - 0.01 15.1 0.0 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 AAAP01003850.1_4 - 0.015 15.3 0.0 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 AAAP01003850.1_4 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 AAAP01003850.1_4 - 0.12 12.0 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) sCache_2 PF17200.4 AAAP01003850.1_5 - 1.3e-38 132.3 0.4 5.1e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003850.1_5 - 7.1e-35 120.6 1.9 1.5e-33 116.2 0.0 2.8 3 0 0 3 3 3 1 Cache domain MCPsignal PF00015.21 AAAP01003850.1_5 - 2e-29 102.6 48.3 1.1e-28 100.1 24.5 3.4 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003850.1_5 - 1.1e-10 41.6 0.7 1.1e-10 41.6 0.7 3.1 3 0 0 3 3 3 1 HAMP domain Cache_3-Cache_2 PF17201.4 AAAP01003850.1_5 - 4.4e-10 39.3 0.1 2.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Cache 3/Cache 2 fusion domain DUF416 PF04222.12 AAAP01003850.1_5 - 0.013 14.9 2.8 0.072 12.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF416) DUF4229 PF14012.6 AAAP01003850.1_5 - 0.029 14.4 0.7 0.029 14.4 0.7 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF4229) FlaC_arch PF05377.11 AAAP01003850.1_5 - 0.25 11.8 1.0 7.3 7.1 0.0 3.3 4 0 0 4 4 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 AAAP01003850.1_5 - 0.26 11.5 17.3 2.2 8.5 0.7 3.5 3 0 0 3 3 3 0 Flagellar FliJ protein ZapB PF06005.12 AAAP01003850.1_5 - 0.42 11.1 2.7 14 6.2 0.7 3.0 3 0 0 3 3 2 0 Cell division protein ZapB TruB_N PF01509.18 AAAP01003850.1_5 - 0.44 10.9 6.0 1.5 9.1 0.5 3.2 3 1 0 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) dCache_1 PF02743.18 AAAP01003850.1_5 - 0.49 10.1 0.0 0.49 10.1 0.0 3.4 3 1 0 3 3 3 0 Cache domain DUF1664 PF07889.12 AAAP01003850.1_5 - 0.53 10.3 12.2 1.2 9.1 0.8 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003850.1_5 - 0.97 9.7 30.7 1 9.6 0.4 6.3 2 1 3 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 AAAP01003850.1_5 - 1.2 8.4 33.8 0.12 11.7 4.4 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) SKA1 PF07160.12 AAAP01003850.1_5 - 2.2 8.1 5.0 4.8 7.0 0.1 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Laminin_I PF06008.14 AAAP01003850.1_5 - 8.3 6.0 29.4 0.48 10.1 5.7 3.9 1 1 0 4 4 4 0 Laminin Domain I MaoC_dehydratas PF01575.19 AAAP01003850.1_6 - 1.8e-18 66.2 0.0 5.8e-18 64.6 0.0 1.7 1 1 1 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01003850.1_6 - 9e-06 25.9 0.0 2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase FabA PF07977.13 AAAP01003850.1_6 - 0.017 14.7 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain DAHP_synth_2 PF01474.16 AAAP01003850.1_7 - 7.5e-209 693.7 0.0 8.5e-209 693.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Tsi6 PF18660.1 AAAP01003850.1_7 - 0.031 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Tsi6 Methyltransf_25 PF13649.6 AAAP01003850.1_8 - 2.7e-07 31.2 0.0 4.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003850.1_8 - 3.1e-06 27.8 0.0 4.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 AAAP01003850.1_8 - 4.1e-05 23.4 0.0 9.6e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 AAAP01003850.1_8 - 0.00011 22.8 0.0 0.00016 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003850.1_8 - 0.0039 17.0 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 AAAP01003850.1_8 - 0.027 14.0 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase ILVD_EDD PF00920.21 AAAP01003850.1_8 - 0.15 10.6 0.0 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 Dehydratase family PrmA PF06325.13 AAAP01003850.1_8 - 0.16 11.3 0.7 0.25 10.7 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HTH_Crp_2 PF13545.6 AAAP01003850.1_9 - 2e-14 53.3 1.8 3.6e-14 52.5 1.8 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003850.1_9 - 1.5e-09 37.8 0.0 3.7e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Crp PF00325.20 AAAP01003850.1_9 - 2.4e-06 27.1 0.6 6e-06 25.8 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family Rrf2 PF02082.20 AAAP01003850.1_9 - 0.00069 19.9 0.1 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01003850.1_9 - 0.0014 18.5 2.4 0.0028 17.5 1.0 2.2 1 1 1 2 2 2 1 MarR family HTH_24 PF13412.6 AAAP01003850.1_9 - 0.02 14.5 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAAP01003850.1_9 - 0.035 14.0 0.1 0.092 12.7 0.1 1.7 1 1 1 2 2 2 0 MarR family CCP_MauG PF03150.14 AAAP01003850.1_10 - 5.2e-53 179.7 0.2 1.9e-52 177.9 0.0 1.8 2 0 0 2 2 2 1 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 AAAP01003850.1_10 - 0.00022 22.3 2.3 0.28 12.4 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c DUF1924 PF09086.11 AAAP01003850.1_10 - 0.041 14.2 0.2 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrome_CBB3 PF13442.6 AAAP01003850.1_10 - 0.062 13.6 4.0 6.3 7.2 0.9 2.7 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AAAP01003850.1_10 - 0.12 12.4 0.3 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c rve PF00665.26 AAAP01003850.1_11 - 9.7e-26 90.3 0.0 1.5e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AAAP01003850.1_11 - 1.3e-21 76.2 0.2 2.3e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AAAP01003850.1_11 - 1.9e-05 24.7 0.4 3.7e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 AAAP01003850.1_11 - 0.00084 19.5 0.2 0.0042 17.2 0.0 2.2 2 1 1 3 3 3 1 Integrase core domain HTH_Tnp_1 PF01527.20 AAAP01003850.1_12 - 5.6e-19 68.2 0.0 7.2e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AAAP01003850.1_12 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003850.1_12 - 0.018 15.1 0.0 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003850.1_12 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AAAP01003850.1_12 - 0.054 13.6 0.1 0.07 13.3 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF4242 PF14026.6 AAAP01003850.1_13 - 5.6e-18 64.9 0.0 6.7e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4242) PGM1_C PF18105.1 AAAP01003850.1_13 - 0.0024 17.3 1.0 0.0045 16.5 1.0 1.4 1 0 0 1 1 1 1 PGM1 C-terminal domain DctP PF03480.13 AAAP01003850.1_14 - 1.8e-57 194.8 0.0 2.4e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Guanylate_cyc PF00211.20 AAAP01003850.1_15 - 5.2e-27 94.6 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 AAAP01003850.1_15 - 1.6e-21 77.2 0.0 2.6e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Cache domain Cache_3-Cache_2 PF17201.4 AAAP01003850.1_15 - 1.1e-06 28.1 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain HAMP PF00672.25 AAAP01003850.1_15 - 0.0001 22.6 1.0 0.00022 21.5 0.2 2.0 2 0 0 2 2 2 1 HAMP domain FtsL PF04999.13 AAAP01003850.1_15 - 0.65 10.0 2.0 3 7.9 0.1 2.2 2 0 0 2 2 2 0 Cell division protein FtsL Nitroreductase PF00881.24 AAAP01003850.1_16 - 3.1e-29 102.2 0.0 5.5e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAAP01003850.1_16 - 0.21 11.1 0.0 3.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase ChaC PF04752.12 AAAP01003850.1_17 - 5.5e-48 163.4 0.0 6.3e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 AAAP01003850.1_17 - 0.00015 22.3 0.0 0.00023 21.7 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 AAAP01003850.1_17 - 0.2 12.1 0.0 0.31 11.5 0.0 1.2 1 0 0 1 1 1 0 AIG2-like family DUF3095 PF11294.8 AAAP01003850.1_20 - 1.1e-124 416.3 0.0 1.3e-124 416.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) NAD_synthase PF02540.17 AAAP01003850.1_21 - 3.9e-71 239.0 0.0 5.2e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 AAAP01003850.1_21 - 1.8e-28 99.6 0.0 2.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_Me_trans PF03054.16 AAAP01003850.1_21 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.21 AAAP01003850.1_21 - 0.033 13.9 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 AAAP01003850.1_21 - 0.05 13.1 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Osmo_MPGsynth PF09488.10 AAAP01003850.1_21 - 0.18 10.4 0.0 0.59 8.8 0.0 1.7 2 0 0 2 2 2 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Cation_efflux PF01545.21 AAAP01003850.1_22 - 4.8e-36 124.4 10.5 6.6e-36 123.9 10.5 1.2 1 0 0 1 1 1 1 Cation efflux family Zn_peptidase_2 PF04298.12 AAAP01003850.1_22 - 4.2 6.7 7.0 1.2 8.5 1.4 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase tRNA-synt_1c PF00749.21 AAAP01003850.1_23 - 4.8e-66 222.8 0.0 6.1e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1e PF01406.19 AAAP01003850.1_24 - 7.5e-117 390.0 0.0 9.1e-117 389.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AAAP01003850.1_24 - 2e-10 41.0 0.0 4.5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 AAAP01003850.1_24 - 3.4e-07 29.3 0.0 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 AAAP01003850.1_24 - 3e-06 26.4 0.0 0.0017 17.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 AAAP01003850.1_24 - 2.2e-05 22.9 0.0 3.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) ATP-grasp_5 PF13549.6 AAAP01003850.1_26 - 1e-78 263.8 0.1 1.5e-78 263.3 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AAAP01003850.1_26 - 1.1e-47 161.3 0.0 2.2e-47 160.3 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AAAP01003850.1_26 - 5.8e-24 84.8 0.4 2.5e-21 76.4 0.0 3.9 4 0 0 4 4 4 1 CoA binding domain Acetyltransf_3 PF13302.7 AAAP01003850.1_26 - 4.3e-08 33.9 0.0 1e-07 32.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 AAAP01003850.1_26 - 1.2e-07 32.3 0.0 3.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Acetyltransf_1 PF00583.25 AAAP01003850.1_26 - 1.8e-07 31.4 0.0 3.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AAAP01003850.1_26 - 0.0001 22.5 0.0 0.00031 20.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AAAP01003850.1_26 - 0.0038 16.9 0.1 0.013 15.2 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003850.1_26 - 0.0082 16.1 0.1 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Nudix_hydro PF18290.1 AAAP01003850.1_26 - 0.018 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain Acetyltransf_10 PF13673.7 AAAP01003850.1_26 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SMC_N PF02463.19 AAAP01003850.1_27 - 2.3e-24 86.1 0.0 3.2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AAAP01003850.1_27 - 6e-07 29.6 0.0 7.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003850.1_27 - 1.4e-06 29.0 0.0 1.9e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01003850.1_27 - 0.0004 20.2 0.0 0.00048 20.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AAAP01003850.1_27 - 0.003 18.1 0.0 0.0061 17.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AAAP01003850.1_27 - 0.0088 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AWPM-19 PF05512.11 AAAP01003850.1_27 - 0.14 12.4 0.6 0.23 11.6 0.6 1.3 1 0 0 1 1 1 0 AWPM-19-like family RsgA_GTPase PF03193.16 AAAP01003850.1_27 - 0.24 11.3 0.0 0.44 10.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase HTH_17 PF12728.7 AAAP01003851.1_2 - 3.7e-08 33.4 0.1 6.1e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003851.1_2 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AAAP01003851.1_2 - 0.0037 17.2 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 AAAP01003851.1_2 - 0.0094 16.1 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_28 PF13518.6 AAAP01003851.1_2 - 0.035 14.2 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MerR_1 PF13411.6 AAAP01003851.1_2 - 0.074 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein Phage_integrase PF00589.22 AAAP01003851.1_3 - 1.8e-06 27.9 0.2 3.8e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AAAP01003851.1_3 - 0.048 14.0 0.0 0.2 12.0 0.0 2.0 2 1 0 2 2 2 0 Phage integrase SAM-like domain Phage_integrase PF00589.22 AAAP01003851.1_4 - 0.0083 15.9 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family HTH_Tnp_ISL3 PF13542.6 AAAP01003851.1_4 - 0.012 15.0 1.5 0.013 14.9 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF2711 PF10924.8 AAAP01003851.1_4 - 0.05 13.2 0.1 0.051 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Formyl_trans_N PF00551.19 AAAP01003851.1_5 - 4.4e-08 33.1 0.0 6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Statherin PF03875.13 AAAP01003851.1_5 - 2 8.5 5.8 6.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Statherin GATase PF00117.28 AAAP01003851.1_6 - 2.5e-55 187.2 0.0 2.8e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01003851.1_6 - 2.1e-12 47.3 0.0 6.6e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.21 AAAP01003851.1_7 - 3.6e-97 324.9 2.9 4.6e-97 324.5 2.9 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AAAP01003851.1_7 - 5.1e-19 67.9 0.9 1.3e-18 66.6 0.9 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain IGPS PF00218.21 AAAP01003851.1_8 - 3.4e-94 314.8 0.0 3.8e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase MoaC PF01967.21 AAAP01003851.1_9 - 1.9e-58 196.4 3.6 2.2e-58 196.2 3.6 1.0 1 0 0 1 1 1 1 MoaC family MoeA_N PF03453.17 AAAP01003851.1_10 - 2.3e-41 141.2 3.2 3.3e-41 140.7 3.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAAP01003851.1_10 - 5.6e-24 84.4 0.2 1.6e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAAP01003851.1_10 - 7.9e-16 58.0 0.1 4.9e-15 55.5 0.0 2.4 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) LexA_DNA_bind PF01726.16 AAAP01003851.1_11 - 5.3e-14 51.8 0.1 1.6e-12 47.0 0.1 2.3 2 0 0 2 2 2 1 LexA DNA binding domain Peptidase_S24 PF00717.23 AAAP01003851.1_11 - 7.8e-12 45.0 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like MarR_2 PF12802.7 AAAP01003851.1_11 - 0.0069 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01003851.1_11 - 0.017 15.0 0.1 0.043 13.7 0.1 1.7 1 1 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AAAP01003851.1_11 - 0.031 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF1967 PF09269.11 AAAP01003851.1_11 - 0.043 13.8 0.3 0.66 10.0 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1967) Rbsn PF11464.8 AAAP01003851.1_12 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Rabenosyn Rab binding domain AMP-binding PF00501.28 AAAP01003851.1_14 - 3.5e-90 302.6 0.0 4.3e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003851.1_14 - 6.5e-20 71.9 2.0 1.9e-19 70.4 1.5 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 AAAP01003851.1_15 - 1e-32 113.5 0.0 1.6e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003851.1_15 - 2.4e-05 24.3 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AAAP01003851.1_15 - 0.0001 22.2 0.5 0.00018 21.4 0.5 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAAP01003851.1_15 - 0.00012 21.8 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AAAP01003851.1_15 - 0.00049 19.7 0.2 0.088 12.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AAAP01003851.1_15 - 0.00068 20.1 0.1 0.0012 19.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003851.1_15 - 0.0056 17.0 0.5 0.079 13.2 0.5 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AAAP01003851.1_15 - 0.015 14.7 0.0 0.04 13.4 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AAAP01003851.1_15 - 0.019 15.0 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AAAP01003851.1_15 - 0.036 14.0 0.5 0.079 12.9 0.2 1.7 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 AAAP01003851.1_15 - 0.06 12.3 0.5 0.11 11.4 0.3 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 AAAP01003851.1_15 - 0.093 12.6 0.5 2.4 8.0 0.2 2.1 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 AAAP01003851.1_15 - 0.17 11.6 0.9 0.88 9.3 0.5 2.2 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 AAAP01003851.1_15 - 0.18 10.6 0.7 4.7 5.9 0.1 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 AAAP01003851.1_15 - 0.19 11.4 0.5 1.1 8.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain OHCU_decarbox PF09349.10 AAAP01003851.1_15 - 0.22 12.0 0.0 0.31 11.5 0.0 1.2 1 0 0 1 1 1 0 OHCU decarboxylase AAA_23 PF13476.6 AAAP01003851.1_15 - 0.25 11.8 0.0 0.33 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003851.1_16 - 1.2e-27 97.1 0.0 1.5e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003851.1_16 - 3.8e-05 23.6 0.4 0.01 15.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 AAAP01003851.1_16 - 0.00074 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 AAAP01003851.1_16 - 0.0012 18.4 0.4 0.068 12.6 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003851.1_16 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003851.1_16 - 0.0019 18.6 0.1 0.0037 17.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AAAP01003851.1_16 - 0.0034 17.9 0.2 0.0052 17.3 0.2 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003851.1_16 - 0.005 16.8 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ATP_bind_1 PF03029.17 AAAP01003851.1_16 - 0.0073 16.1 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 AAAP01003851.1_16 - 0.0093 16.0 0.1 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AAAP01003851.1_16 - 0.02 14.6 0.6 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AAAP01003851.1_16 - 0.056 13.0 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003851.1_16 - 0.056 13.7 0.1 0.25 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 AAAP01003851.1_16 - 0.092 11.6 0.1 0.2 10.6 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 AAAP01003851.1_16 - 0.11 12.2 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AAAP01003851.1_16 - 0.13 12.4 0.1 0.21 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AAAP01003851.1_16 - 0.21 11.6 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family BPD_transp_2 PF02653.16 AAAP01003851.1_17 - 9.8e-37 126.6 43.4 1.5e-36 125.9 43.0 1.5 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01003851.1_18 - 1.8e-41 142.1 41.0 2.2e-41 141.8 41.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Phage_HK97_TLTM PF06120.11 AAAP01003851.1_18 - 9.7 5.3 5.0 14 4.8 5.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Peripla_BP_6 PF13458.6 AAAP01003851.1_19 - 7e-70 236.4 12.1 8.5e-70 236.1 12.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003851.1_19 - 1.9e-26 92.9 0.0 2.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003851.1_19 - 2.2e-10 40.2 0.0 2.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region LppC PF04348.13 AAAP01003851.1_19 - 1.9e-07 30.3 0.3 2.8e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 LppC putative lipoprotein Metal_resist PF13801.6 AAAP01003851.1_19 - 0.11 12.6 0.4 0.22 11.7 0.4 1.4 1 0 0 1 1 1 0 Heavy-metal resistance FAA_hydrolase PF01557.18 AAAP01003851.1_20 - 1.1e-51 175.5 0.0 1.3e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HATPase_c PF02518.26 AAAP01003851.1_21 - 2.9e-21 76.1 0.0 6e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003851.1_21 - 6.8e-12 45.2 0.1 6.4e-10 38.9 0.0 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 AAAP01003851.1_21 - 4.4e-07 30.0 0.0 9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Cache domain HATPase_c_5 PF14501.6 AAAP01003851.1_21 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 1 1 0 1 1 1 0 GHKL domain HATPase_c_3 PF13589.6 AAAP01003851.1_21 - 0.026 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NifU_N PF01592.16 AAAP01003851.1_23 - 5.6e-06 26.5 0.0 6.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Aminotran_5 PF00266.19 AAAP01003851.1_24 - 3e-120 401.6 0.0 3.4e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AAAP01003851.1_24 - 1.3e-05 24.6 0.0 0.00017 20.9 0.0 2.1 2 1 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01003851.1_24 - 0.00012 20.7 0.0 0.00024 19.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01003851.1_24 - 0.039 13.3 0.1 0.071 12.4 0.1 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NTP_transf_3 PF12804.7 AAAP01003851.1_25 - 3.3e-40 138.0 3.4 4.4e-40 137.7 3.4 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003851.1_25 - 4.4e-05 23.3 0.1 6.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FAD_binding_5 PF00941.21 AAAP01003851.1_26 - 1.7e-40 138.6 0.1 2.1e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 AAAP01003851.1_26 - 0.00092 19.3 2.9 0.0014 18.8 0.1 2.5 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 AAAP01003851.1_27 - 9.2e-30 102.5 3.6 1.1e-29 102.3 0.1 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003851.1_27 - 1.5e-07 31.3 0.8 1.5e-07 31.3 0.8 1.9 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AAAP01003851.1_27 - 0.00021 21.2 1.0 0.00052 20.0 1.0 1.8 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01003851.1_27 - 0.0033 17.4 0.7 0.0033 17.4 0.7 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4065 PF13274.6 AAAP01003851.1_28 - 1.1e-06 29.5 0.0 4.7e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4065) Glyco_hydro_25 PF01183.20 AAAP01003851.1_29 - 3.2e-25 89.3 0.0 3.4e-24 86.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 25 Polysacc_deac_1 PF01522.21 AAAP01003851.1_30 - 1.8e-33 115.1 0.0 2.5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AAAP01003851.1_30 - 0.00086 19.0 0.0 0.005 16.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) MFS_1 PF07690.16 AAAP01003851.1_31 - 2.1e-36 125.6 69.4 8.4e-31 107.2 43.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01003851.1_31 - 1.8e-07 30.8 36.0 0.00016 21.1 8.4 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 AAAP01003851.1_31 - 1.7 7.4 13.4 0.12 11.1 0.9 2.3 2 0 0 2 2 2 0 LacY proton/sugar symporter TetR_N PF00440.23 AAAP01003851.1_32 - 3.9e-13 49.0 0.2 3.9e-13 49.0 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAAP01003851.1_32 - 0.0069 16.6 2.4 0.0069 16.6 2.4 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain OHCU_decarbox PF09349.10 AAAP01003851.1_32 - 0.022 15.3 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 OHCU decarboxylase HTH_IclR PF09339.10 AAAP01003851.1_32 - 0.051 13.4 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain Oxidored_FMN PF00724.20 AAAP01003851.1_33 - 9.7e-64 215.8 0.0 1.1e-63 215.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AAAP01003851.1_33 - 0.00053 19.2 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 AAAP01003851.1_33 - 0.031 13.7 0.1 0.075 12.5 0.1 1.6 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 AAAP01003851.1_33 - 0.088 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 AAAP01003851.1_33 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase SDF PF00375.18 AAAP01003851.1_34 - 9.8e-103 344.2 34.8 1.1e-102 344.0 34.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MFS_1 PF07690.16 AAAP01003851.1_35 - 6.4e-34 117.4 42.2 6.4e-34 117.4 42.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EIID-AGA PF03613.14 AAAP01003851.1_35 - 0.044 12.9 2.2 0.093 11.9 2.2 1.5 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component DUF2583 PF10762.9 AAAP01003851.1_35 - 0.37 11.2 4.9 0.52 10.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) UCR_UQCRX_QCR9 PF05365.12 AAAP01003851.1_35 - 2.5 8.1 6.0 4 7.4 0.0 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like HATPase_c PF02518.26 AAAP01003851.1_37 - 0.013 16.0 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NMT1 PF09084.11 AAAP01003852.1_2 - 8.9e-10 38.9 0.0 7.4e-09 35.9 0.0 1.9 1 1 1 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.7 AAAP01003852.1_2 - 3.5e-05 23.5 0.0 7.8e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AAAP01003852.1_2 - 4.9e-05 22.9 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 AAAP01003852.1_2 - 0.0057 16.4 0.2 0.79 9.4 0.0 2.2 2 0 0 2 2 2 2 NMT1-like family Rhodanese PF00581.20 AAAP01003852.1_3 - 0.0016 19.0 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain sCache_2 PF17200.4 AAAP01003852.1_4 - 1e-15 57.9 0.2 1.4e-15 57.5 0.2 1.2 1 0 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003852.1_4 - 2.1e-14 53.4 0.2 2.8e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 Cache domain Cytochrom_C PF00034.21 AAAP01003852.1_4 - 9.6e-08 33.1 0.0 6.2e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c Cache_3-Cache_2 PF17201.4 AAAP01003852.1_4 - 0.0046 16.3 0.1 0.0061 15.9 0.1 1.1 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain Cytochrome_CBB3 PF13442.6 AAAP01003852.1_4 - 0.0047 17.2 0.3 0.046 14.1 0.1 2.4 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Ish1 PF10281.9 AAAP01003852.1_4 - 0.08 13.3 0.0 3 8.2 0.1 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Fer4_5 PF12801.7 AAAP01003852.1_5 - 3.7e-12 46.0 18.5 1.9e-10 40.5 2.7 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain FMN_bind PF04205.14 AAAP01003852.1_5 - 0.0012 19.3 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 FMN-binding domain Peptidase_M48 PF01435.18 AAAP01003852.1_6 - 2.1e-17 63.6 0.0 3.2e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 AAAP01003852.1_6 - 0.0026 17.6 0.1 0.0073 16.1 0.0 1.7 2 0 0 2 2 2 1 SprT-like family DUF2201_N PF13203.6 AAAP01003852.1_6 - 0.024 14.2 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain PqqD PF05402.12 AAAP01003852.1_7 - 8.2e-10 38.8 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Radical_SAM PF04055.21 AAAP01003852.1_8 - 2e-20 73.9 0.0 3.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AAAP01003852.1_8 - 5.5e-07 30.0 1.0 1.6e-06 28.5 0.1 2.2 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AAAP01003852.1_8 - 3.4e-05 24.1 0.0 6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003852.1_8 - 0.0018 18.4 0.0 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 AAAP01003852.1_8 - 0.084 12.3 0.1 3.1 7.2 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Hydrolase PF00702.26 AAAP01003852.1_8 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ThiS PF02597.20 AAAP01003852.1_9 - 0.0032 18.1 0.0 0.0055 17.3 0.0 1.4 1 1 0 1 1 1 1 ThiS family TGS PF02824.21 AAAP01003852.1_9 - 0.05 13.7 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 TGS domain Urate_ox_N PF06181.11 AAAP01003852.1_11 - 1.7e-10 40.8 4.6 2.4e-06 27.1 0.0 2.9 2 1 1 3 3 3 3 Urate oxidase N-terminal FIST PF08495.10 AAAP01003852.1_12 - 6e-32 111.0 0.6 4.7e-31 108.1 0.2 2.1 2 0 0 2 2 2 1 FIST N domain FIST_C PF10442.9 AAAP01003852.1_12 - 9.1e-14 51.6 0.2 7.3e-12 45.4 0.1 2.5 2 0 0 2 2 2 2 FIST C domain PAS_7 PF12860.7 AAAP01003852.1_13 - 4.8e-63 210.4 0.0 8.8e-36 122.6 0.0 2.7 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAAP01003852.1_13 - 4.2e-19 69.1 0.0 7.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AAAP01003852.1_13 - 1e-08 35.0 0.1 0.0068 16.4 0.0 3.0 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 AAAP01003852.1_13 - 2.8e-08 33.7 0.3 2.8e-08 33.7 0.3 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AAAP01003852.1_13 - 1.5e-07 31.6 0.0 3.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 AAAP01003852.1_13 - 3.1e-07 30.6 0.4 0.048 13.9 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AAAP01003852.1_13 - 0.011 15.7 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 0 PAS fold DASH_Duo1 PF08651.10 AAAP01003852.1_13 - 0.022 14.5 0.2 6.3 6.6 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 Syntaxin-6_N PF09177.11 AAAP01003852.1_13 - 0.12 13.0 6.3 4.7 7.8 0.3 3.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal T2SSB PF16537.5 AAAP01003852.1_13 - 0.14 11.8 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Type II secretion system protein B Baculo_PEP_C PF04513.12 AAAP01003852.1_13 - 1.4 9.0 6.4 8.6 6.4 2.9 3.4 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GerE PF00196.19 AAAP01003852.1_14 - 1.3e-20 72.7 0.8 3.5e-20 71.3 0.8 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AAAP01003852.1_14 - 4.4e-16 59.0 0.0 7.7e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AAAP01003852.1_14 - 4.5e-07 29.4 0.1 9.3e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003852.1_14 - 0.00064 19.2 0.2 0.0016 17.9 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AAAP01003852.1_14 - 0.037 13.8 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 AAAP01003852.1_14 - 0.041 13.9 0.8 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Trans_reg_C PF00486.28 AAAP01003852.1_14 - 0.044 13.9 2.1 0.27 11.3 2.1 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal HTH_10 PF04967.12 AAAP01003852.1_14 - 0.05 13.4 0.2 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 HTH DNA binding domain TonB_C PF03544.14 AAAP01003852.1_15 - 3e-10 40.4 0.0 6.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAAP01003852.1_15 - 0.011 16.0 0.0 0.047 13.9 0.0 2.1 2 1 0 2 2 2 0 TonB C terminal TolA PF06519.11 AAAP01003852.1_15 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 TolA C-terminal HATPase_c PF02518.26 AAAP01003852.1_16 - 1.2e-22 80.5 0.0 2.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE5 PF17149.4 AAAP01003852.1_16 - 1.3e-16 60.4 0.0 2.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic sensor domain found in signal transduction proteins HisKA PF00512.25 AAAP01003852.1_16 - 5.4e-06 26.3 0.1 5.4e-06 26.3 0.1 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003852.1_16 - 9.5e-05 22.4 1.2 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003852.1_16 - 0.0091 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PhoR PF11808.8 AAAP01003852.1_16 - 0.059 13.8 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR HAMP PF00672.25 AAAP01003852.1_16 - 0.071 13.5 6.0 0.12 12.8 1.3 3.4 2 1 1 3 3 3 0 HAMP domain HATPase_c_5 PF14501.6 AAAP01003852.1_16 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Helo_like_N PF17111.5 AAAP01003852.1_16 - 0.13 11.6 0.4 8.7 5.6 0.1 2.9 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins SBP_bac_3 PF00497.20 AAAP01003852.1_17 - 5.4e-08 32.5 0.0 1.8e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 AAAP01003852.1_17 - 0.00082 18.8 0.0 0.066 12.6 0.0 2.5 1 1 1 2 2 2 2 LysR substrate binding domain Enolase_C PF00113.22 AAAP01003852.1_18 - 1.7e-130 434.6 0.4 2.1e-130 434.3 0.4 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AAAP01003852.1_18 - 1.7e-60 202.9 0.0 3.7e-60 201.8 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AAAP01003852.1_18 - 2.4e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AAAP01003852.1_18 - 8.9e-05 21.8 0.2 0.0002 20.6 0.2 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DAHP_synth_1 PF00793.20 AAAP01003852.1_19 - 5.1e-71 238.8 0.0 5.9e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CTP_synth_N PF06418.14 AAAP01003852.1_20 - 2e-121 404.3 0.0 2.6e-121 403.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AAAP01003852.1_20 - 1.5e-54 184.6 0.0 2.2e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01003852.1_20 - 1.6e-08 34.6 0.0 3.6e-07 30.2 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 AAAP01003852.1_20 - 0.027 14.5 0.0 0.043 13.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SecG PF03840.14 AAAP01003852.1_21 - 1.2e-16 60.5 10.5 1.7e-16 60.0 9.8 1.5 2 0 0 2 2 2 1 Preprotein translocase SecG subunit Peptidase_S9 PF00326.21 AAAP01003852.1_21 - 0.025 14.0 0.2 0.027 13.9 0.2 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family TIM PF00121.18 AAAP01003852.1_22 - 1.5e-85 286.5 0.0 1.7e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Methyltransf_11 PF08241.12 AAAP01003852.1_23 - 7.4e-19 68.2 0.0 1.6e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003852.1_23 - 2.9e-18 66.3 0.0 7.3e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003852.1_23 - 6.3e-17 62.2 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003852.1_23 - 2.7e-14 53.4 0.0 4.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003852.1_23 - 3.5e-14 52.9 0.0 1.2e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TPR_19 PF14559.6 AAAP01003852.1_23 - 6.6e-10 39.4 0.8 0.00027 21.4 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat NodS PF05401.11 AAAP01003852.1_23 - 3.1e-09 36.8 0.0 5.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPR_14 PF13428.6 AAAP01003852.1_23 - 1.1e-07 32.1 6.2 0.5 11.3 0.0 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003852.1_23 - 1.8e-07 30.8 0.2 0.012 15.7 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003852.1_23 - 1.5e-06 27.8 0.3 12 6.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003852.1_23 - 1.5e-06 28.4 1.7 0.018 15.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003852.1_23 - 4.1e-06 26.9 2.0 0.33 11.7 0.0 4.6 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003852.1_23 - 1.6e-05 24.5 0.0 0.015 15.1 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003852.1_23 - 2.9e-05 23.8 3.5 0.34 10.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003852.1_23 - 0.00032 20.8 1.4 0.055 13.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Ubie_methyltran PF01209.18 AAAP01003852.1_23 - 0.00094 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPR_11 PF13414.6 AAAP01003852.1_23 - 0.0037 16.9 0.0 2.3 7.9 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPMT PF05724.11 AAAP01003852.1_23 - 0.0097 15.6 0.0 0.097 12.3 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 AAAP01003852.1_23 - 0.012 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain BTAD PF03704.17 AAAP01003852.1_23 - 0.014 15.8 1.0 0.59 10.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain CheR PF01739.18 AAAP01003852.1_23 - 0.025 14.1 0.0 5.3 6.5 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PPR PF01535.20 AAAP01003852.1_23 - 0.035 14.4 0.3 1.6 9.1 0.0 3.2 3 0 0 3 3 2 0 PPR repeat TPR_8 PF13181.6 AAAP01003852.1_23 - 0.036 14.3 0.0 5.5 7.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003852.1_23 - 0.062 14.0 5.0 10 6.9 0.1 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat PrmA PF06325.13 AAAP01003852.1_23 - 0.073 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01003852.1_23 - 0.092 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 AAAP01003852.1_23 - 0.098 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 AAAP01003852.1_23 - 0.13 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TPR_20 PF14561.6 AAAP01003852.1_23 - 0.15 12.4 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 AAAP01003852.1_23 - 0.25 10.7 0.0 1.3 8.4 0.0 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit Hemerythrin PF01814.23 AAAP01003852.1_24 - 2.3e-08 34.7 4.0 4.1e-08 33.9 4.0 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain UvrB_inter PF17757.1 AAAP01003852.1_24 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 UvrB interaction domain DUF1641 PF07849.11 AAAP01003852.1_25 - 6.5e-06 25.9 0.2 0.001 18.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1641) Phage_mat-A PF03863.13 AAAP01003852.1_25 - 0.025 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Phage maturation protein Pyr_redox_2 PF07992.14 AAAP01003852.1_26 - 2e-17 63.4 0.0 2.7e-12 46.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01003852.1_26 - 0.00024 21.1 0.4 0.45 10.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 AAAP01003852.1_26 - 0.12 11.5 0.2 6 5.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TusA PF01206.17 AAAP01003852.1_27 - 3.2e-20 71.7 0.0 3.5e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DrsE_2 PF13686.6 AAAP01003852.1_28 - 0.00049 20.0 0.1 0.79 9.6 0.0 2.0 1 1 1 2 2 2 2 DsrE/DsrF/DrsH-like family DrsE PF02635.15 AAAP01003852.1_28 - 0.00064 20.1 0.0 0.00075 19.8 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family Rotamase_2 PF13145.6 AAAP01003852.1_29 - 1.1e-44 152.1 10.5 4.8e-28 98.4 0.3 4.4 4 1 0 4 4 4 4 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AAAP01003852.1_29 - 5.4e-40 136.8 0.3 1.3e-38 132.3 0.0 2.6 3 0 0 3 3 3 1 SurA N-terminal domain SurA_N_2 PF13623.6 AAAP01003852.1_29 - 7.4e-19 68.1 0.0 3.4e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 SurA N-terminal domain Rotamase PF00639.21 AAAP01003852.1_29 - 7e-10 39.7 2.8 1.2e-06 29.3 0.0 3.5 3 0 0 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAAP01003852.1_29 - 3.4e-06 27.6 4.4 8.2e-05 23.1 0.0 3.4 4 0 0 4 4 4 1 PPIC-type PPIASE domain Arm-DNA-bind_3 PF13356.6 AAAP01003852.1_29 - 0.3 11.5 3.1 3.7 8.0 0.2 3.3 3 0 0 3 3 3 0 Arm DNA-binding domain Lant_dehydr_C PF14028.6 AAAP01003852.1_29 - 0.4 10.2 3.4 0.23 11.0 0.1 2.3 4 0 0 4 4 4 0 Lantibiotic biosynthesis dehydratase C-term DUF3071 PF11268.8 AAAP01003852.1_29 - 1.1 9.3 5.2 1 9.4 0.9 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3071) Chorismate_bind PF00425.18 AAAP01003852.1_30 - 1e-95 320.2 0.0 1.6e-95 319.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AAAP01003852.1_30 - 5.6e-32 110.9 0.0 5.8e-30 104.4 0.0 3.1 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region DUF835 PF05763.12 AAAP01003852.1_31 - 0.0056 16.4 0.0 0.0061 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF835) Band_7 PF01145.25 AAAP01003852.1_32 - 5.4e-36 124.3 4.1 6.3e-36 124.0 4.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAAP01003852.1_32 - 0.00058 19.6 0.5 0.0028 17.4 0.1 1.9 1 1 1 2 2 2 1 SPFH domain-Band 7 family Rota_NSP4 PF01452.16 AAAP01003852.1_32 - 0.053 13.2 0.1 0.067 12.9 0.1 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein AphA_like PF14557.6 AAAP01003852.1_33 - 3.4e-65 219.0 0.3 3.8e-65 218.9 0.3 1.0 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HMA PF00403.26 AAAP01003852.1_34 - 2.7e-10 40.5 0.2 3.4e-10 40.2 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Polysacc_deac_2 PF04748.13 AAAP01003852.1_35 - 4.6e-80 267.8 0.0 5.7e-80 267.5 0.0 1.1 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase MerR-DNA-bind PF09278.11 AAAP01003852.1_36 - 3e-19 69.3 0.8 6.1e-19 68.3 0.4 1.7 2 0 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 AAAP01003852.1_36 - 9.5e-17 60.5 1.6 9.5e-17 60.5 1.6 1.9 2 0 0 2 2 2 1 MerR family regulatory protein MerR_1 PF13411.6 AAAP01003852.1_36 - 5.6e-16 58.4 0.0 9.1e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_31 PF13560.6 AAAP01003852.1_36 - 0.037 14.4 1.1 0.28 11.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 AAAP01003852.1_36 - 0.066 13.0 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family E1-E2_ATPase PF00122.20 AAAP01003852.1_37 - 8.9e-56 188.3 2.3 8.9e-56 188.3 2.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01003852.1_37 - 8.5e-42 143.8 3.7 1.7e-41 142.8 3.7 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAAP01003852.1_37 - 4.4e-12 46.3 0.0 1.1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AAAP01003852.1_37 - 0.00013 21.8 0.5 0.0011 18.8 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003852.1_37 - 0.0015 19.0 0.7 0.0093 16.4 0.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 AAAP01003852.1_37 - 0.069 13.2 3.0 2.7 8.1 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) MCPsignal PF00015.21 AAAP01003852.1_38 - 0.00017 21.4 12.1 0.00023 21.0 5.2 2.0 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003852.1_38 - 0.0039 17.4 3.3 0.011 16.0 1.1 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AAAP01003852.1_38 - 0.026 14.5 2.4 0.05 13.6 2.3 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.12 AAAP01003852.1_38 - 0.051 13.6 0.9 0.14 12.2 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Vps53_N PF04100.12 AAAP01003852.1_38 - 0.054 12.4 0.9 0.059 12.3 0.9 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal ISG65-75 PF11727.8 AAAP01003852.1_38 - 0.061 12.5 3.7 0.063 12.5 3.7 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein COG6 PF06419.11 AAAP01003852.1_38 - 0.11 10.7 0.2 0.1 10.8 0.2 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 CP_ATPgrasp_2 PF14403.6 AAAP01003853.1_1 - 4.8e-155 516.1 0.0 5.6e-155 515.9 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AAAP01003853.1_1 - 9.7e-147 488.3 0.0 1.2e-146 488.0 0.0 1.1 1 0 0 1 1 1 1 A circularly permuted ATPgrasp GSH-S_ATP PF02955.16 AAAP01003853.1_1 - 0.16 11.3 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Alpha-E PF04168.12 AAAP01003853.1_2 - 6.8e-78 262.4 1.7 7.6e-78 262.2 1.7 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. L27_1 PF09058.10 AAAP01003853.1_2 - 0.0066 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 L27_1 MarR PF01047.22 AAAP01003853.1_3 - 6.2e-16 58.1 0.8 1.2e-15 57.2 0.8 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AAAP01003853.1_3 - 2.5e-12 46.5 2.4 3.1e-12 46.2 0.8 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AAAP01003853.1_3 - 1e-08 35.5 0.3 1e-08 35.5 0.3 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 AAAP01003853.1_3 - 5e-07 29.5 0.0 1.1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HxlR PF01638.17 AAAP01003853.1_3 - 2.9e-06 27.1 0.4 6e-06 26.0 0.3 1.5 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_IclR PF09339.10 AAAP01003853.1_3 - 2.1e-05 24.2 0.8 8.4e-05 22.3 0.4 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 AAAP01003853.1_3 - 0.00058 19.7 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AAAP01003853.1_3 - 0.00088 18.8 0.3 0.0016 17.9 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 AAAP01003853.1_3 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AAAP01003853.1_3 - 0.0022 18.0 0.6 0.006 16.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AAAP01003853.1_3 - 0.01 15.8 0.9 0.032 14.2 0.8 2.0 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain TetR_C_25 PF17933.1 AAAP01003853.1_3 - 0.03 14.6 0.3 2.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rrf2 PF02082.20 AAAP01003853.1_3 - 0.042 14.2 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_45 PF14947.6 AAAP01003853.1_3 - 0.046 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix SMC_ScpB PF04079.16 AAAP01003853.1_3 - 0.062 12.9 0.2 0.1 12.2 0.1 1.6 1 1 0 1 1 1 0 Segregation and condensation complex subunit ScpB PadR PF03551.14 AAAP01003853.1_3 - 0.084 12.8 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Aldedh PF00171.22 AAAP01003853.1_4 - 5.6e-166 552.6 0.3 6.3e-166 552.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SASP PF00269.20 AAAP01003853.1_4 - 0.074 13.1 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Haem_degrading PF03928.14 AAAP01003853.1_5 - 5.7e-31 107.0 3.3 6.3e-31 106.9 3.3 1.0 1 0 0 1 1 1 1 Haem-degrading DUF1244 PF06844.11 AAAP01003853.1_5 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Aminotran_3 PF00202.21 AAAP01003853.1_6 - 3.8e-112 374.9 0.0 4.7e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MarR_2 PF12802.7 AAAP01003853.1_7 - 8.6e-10 38.4 0.1 1.5e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01003853.1_7 - 8.9e-09 35.2 0.1 1.5e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01003853.1_7 - 7.5e-07 29.5 0.1 1.5e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AAAP01003853.1_7 - 0.096 12.6 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 AAAP01003853.1_7 - 0.14 12.2 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DctP PF03480.13 AAAP01003853.1_8 - 1.2e-53 182.3 0.0 1.5e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 DctQ PF04290.12 AAAP01003853.1_9 - 4.9e-20 71.8 1.8 7.2e-20 71.2 1.8 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4383 PF14325.6 AAAP01003853.1_9 - 0.0064 16.8 0.7 0.0064 16.8 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4383) DUF997 PF06196.12 AAAP01003853.1_9 - 0.081 12.9 1.0 2.3 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DctM PF06808.12 AAAP01003853.1_10 - 3.8e-89 299.4 47.6 4.3e-89 299.2 47.6 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Pmp3 PF01679.17 AAAP01003853.1_10 - 0.076 13.2 0.9 0.076 13.2 0.9 4.0 4 1 0 4 4 4 0 Proteolipid membrane potential modulator VPDSG-CTERM PF18205.1 AAAP01003853.1_10 - 0.42 10.5 5.0 2.8 7.9 5.0 2.6 1 0 0 1 1 1 0 VPDSG-CTERM motif Phage_holin_1 PF04531.13 AAAP01003853.1_10 - 7.7 7.1 8.6 1.4 9.5 0.5 3.4 3 1 1 4 4 4 0 Bacteriophage holin FAA_hydrolase PF01557.18 AAAP01003853.1_11 - 2.9e-39 135.0 0.0 3.6e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 AAAP01003853.1_12 - 3.2e-56 190.4 0.0 3.9e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AAAP01003853.1_12 - 0.067 14.1 0.6 0.32 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) Aldedh PF00171.22 AAAP01003853.1_13 - 1.3e-172 574.5 0.2 1.5e-172 574.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LigB PF02900.18 AAAP01003853.1_14 - 3.4e-58 196.9 0.6 3.9e-58 196.7 0.6 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase COR PF16095.5 AAAP01003853.1_14 - 0.037 13.9 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain CHMI PF02962.15 AAAP01003853.1_15 - 2.4e-51 173.3 0.0 2.6e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase Ribosomal_L30 PF00327.20 AAAP01003853.1_15 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e HpcH_HpaI PF03328.14 AAAP01003853.1_17 - 2.6e-60 203.3 0.0 3e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MFS_3 PF05977.13 AAAP01003853.1_18 - 1.1e-53 182.5 36.1 1.3e-53 182.2 36.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAAP01003853.1_18 - 2.6e-26 92.4 74.6 6.9e-23 81.1 43.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 AAAP01003853.1_18 - 0.00086 18.0 6.4 0.00086 18.0 6.4 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein SLATT_fungal PF18142.1 AAAP01003853.1_18 - 0.063 13.3 0.5 0.063 13.3 0.5 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Transketolase_N PF00456.21 AAAP01003853.1_19 - 4.3e-37 127.8 0.0 6.3e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AAAP01003853.1_19 - 2.1e-09 37.0 0.2 0.0015 17.8 0.1 3.0 2 1 0 3 3 3 3 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AAAP01003853.1_19 - 6.6e-09 35.1 0.0 8.9e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AAAP01003853.1_19 - 2.4e-05 24.2 0.2 0.00036 20.3 0.2 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 AAAP01003853.1_19 - 4.1e-05 22.5 0.0 5.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain Transketolase_C PF02780.20 AAAP01003853.1_20 - 4.9e-22 78.1 0.1 1.4e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 AAAP01003853.1_20 - 2.5e-21 76.2 0.0 3.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 AAAP01003853.1_20 - 0.00037 20.7 0.1 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Glyco_trans_4_4 PF13579.6 AAAP01003853.1_21 - 0.033 14.6 0.6 0.086 13.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain B12-binding PF02310.19 AAAP01003853.1_22 - 5e-07 29.8 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 AAAP01003853.1_22 - 0.00026 21.4 0.1 0.0063 16.9 0.1 2.5 2 1 0 2 2 2 1 Radical SAM superfamily Spp-24 PF07448.11 AAAP01003853.1_22 - 2.2 8.5 6.6 2.4 8.4 2.7 2.4 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain Methyltransf_25 PF13649.6 AAAP01003853.1_23 - 0.019 15.7 0.0 0.073 13.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF5319 PF17252.2 AAAP01003853.1_23 - 0.15 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Glyco_trans_1_2 PF13524.6 AAAP01003853.1_24 - 0.0014 19.0 0.0 0.0042 17.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 GHMP_kinases_C PF08544.13 AAAP01003853.1_25 - 2.3e-10 40.7 0.1 6.6e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AAAP01003853.1_25 - 3.2e-10 40.1 0.4 9.5e-10 38.6 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 AAAP01003853.1_25 - 0.083 12.5 0.1 0.26 10.9 0.1 1.8 1 1 0 1 1 1 0 Galactokinase galactose-binding signature NTP_transferase PF00483.23 AAAP01003853.1_26 - 9.8e-21 74.4 0.0 1.2e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003853.1_26 - 4.6e-13 49.8 0.2 4.9e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain GDP_Man_Dehyd PF16363.5 AAAP01003853.1_27 - 8.5e-71 239.0 0.0 1e-70 238.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003853.1_27 - 2.1e-49 168.2 0.0 2.5e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AAAP01003853.1_27 - 5.6e-07 29.0 0.0 9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003853.1_27 - 4.4e-06 26.1 0.0 0.00079 18.7 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003853.1_27 - 0.00035 19.8 0.0 0.00058 19.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01003853.1_27 - 0.0043 16.1 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DEP PF00610.21 AAAP01003853.1_27 - 0.046 13.8 0.0 17 5.6 0.0 2.7 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Phos_pyr_kin PF08543.12 AAAP01003853.1_27 - 0.24 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase dTDP_sugar_isom PF00908.17 AAAP01003853.1_28 - 1.2e-46 158.5 0.0 1.3e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase NUDIX PF00293.28 AAAP01003853.1_29 - 6.6e-11 42.4 0.0 9.5e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.21 AAAP01003853.1_30 - 5.1e-13 49.7 0.1 2.1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003853.1_30 - 4.7e-12 46.0 0.1 4.8e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain Lipase_GDSL_2 PF13472.6 AAAP01003853.1_30 - 0.18 12.2 0.2 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SQHop_cyclase_N PF13249.6 AAAP01003854.1_1 - 5.2e-115 383.5 0.1 6e-115 383.3 0.1 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 AAAP01003854.1_1 - 2.5e-06 27.1 0.0 0.01 15.6 0.0 2.9 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 AAAP01003854.1_1 - 0.0025 17.0 0.0 0.29 10.2 0.0 2.7 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain PSD5 PF07637.11 AAAP01003854.1_1 - 0.15 12.4 0.5 1.8 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) SQS_PSY PF00494.19 AAAP01003854.1_2 - 9.2e-67 225.3 1.2 1.1e-66 225.0 1.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Glyco_tranf_2_3 PF13641.6 AAAP01003854.1_3 - 3e-19 69.8 0.2 4.2e-19 69.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AAAP01003854.1_3 - 8.1e-17 61.5 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAAP01003854.1_3 - 7.5e-13 48.3 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AAAP01003854.1_3 - 0.0018 18.2 2.1 0.0033 17.4 2.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AAAP01003854.1_3 - 0.0094 16.4 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Epimerase PF01370.21 AAAP01003854.1_4 - 1.1e-10 41.4 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AAAP01003854.1_4 - 3.2e-06 26.5 0.0 4.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AAAP01003854.1_4 - 0.0037 16.7 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sel1 PF08238.12 AAAP01003854.1_6 - 3.4e-52 173.7 34.8 3.2e-09 37.2 2.0 7.7 8 0 0 8 8 8 7 Sel1 repeat TPR_7 PF13176.6 AAAP01003854.1_6 - 0.44 10.7 4.6 15 5.9 0.7 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat PPR_long PF17177.4 AAAP01003854.1_6 - 0.76 9.1 4.6 2.4 7.4 0.3 3.3 3 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP ACPS PF01648.20 AAAP01003854.1_7 - 7.2e-15 55.1 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily AMP-binding PF00501.28 AAAP01003854.1_8 - 3.4e-89 299.4 0.0 4.6e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003854.1_8 - 1.2e-11 45.4 0.0 3.5e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 AAAP01003854.1_8 - 3.2e-05 23.5 22.9 0.85 9.4 1.1 7.1 6 1 0 6 6 6 4 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 AAAP01003854.1_8 - 0.00011 22.4 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Phage_holin_3_2 PF04550.12 AAAP01003854.1_8 - 0.16 12.5 2.0 3.5 8.2 0.5 3.0 2 0 0 2 2 2 0 Phage holin family 2 RHH_4 PF13467.6 AAAP01003854.1_9 - 1.2e-27 95.6 0.0 1.3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Ribbon-helix-helix domain Gram_pos_anchor PF00746.21 AAAP01003854.1_10 - 0.078 12.9 1.5 0.085 12.8 1.5 1.1 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF2934 PF11154.8 AAAP01003854.1_12 - 6.7e-14 51.3 3.6 6.7e-14 51.3 3.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2934) FlaF PF07309.11 AAAP01003854.1_12 - 0.069 13.2 1.1 0.48 10.4 1.1 2.1 1 1 0 1 1 1 0 Flagellar protein FlaF EAL PF00563.20 AAAP01003854.1_13 - 1.8e-71 240.4 0.0 3.3e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003854.1_13 - 1e-44 152.2 0.0 1.8e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAAP01003854.1_13 - 2.7e-17 62.8 0.0 1e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01003854.1_13 - 3.9e-13 49.6 0.0 7.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain HAMP PF00672.25 AAAP01003854.1_13 - 5.7e-13 49.0 0.3 1.3e-12 47.8 0.3 1.7 1 0 0 1 1 1 1 HAMP domain dCache_1 PF02743.18 AAAP01003854.1_13 - 8.7e-10 38.8 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Cache domain PAS_8 PF13188.7 AAAP01003854.1_13 - 1.5e-09 37.7 0.0 4.5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003854.1_13 - 1e-06 28.9 0.1 3.3e-06 27.3 0.1 2.0 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 AAAP01003854.1_13 - 0.0054 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold Phage_holin_3_6 PF07332.11 AAAP01003854.1_13 - 0.01 15.8 6.8 0.68 10.0 0.3 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PAS_10 PF13596.6 AAAP01003854.1_13 - 0.061 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain ABC_sub_bind PF04392.12 AAAP01003854.1_14 - 1.9e-42 145.5 0.0 2.3e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_6 PF13458.6 AAAP01003854.1_14 - 0.0017 18.1 0.1 0.0024 17.6 0.1 1.4 1 1 0 1 1 1 1 Periplasmic binding protein DUF3572 PF12096.8 AAAP01003854.1_16 - 9.6e-30 102.6 3.9 1.1e-29 102.5 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3572) FtsK_SpoIIIE PF01580.18 AAAP01003854.1_16 - 0.083 12.2 0.0 0.094 12.1 0.0 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3199 PF11436.8 AAAP01003854.1_17 - 0.13 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) DUF1822 PF08852.11 AAAP01003854.1_18 - 0.095 11.7 0.0 1 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) Gaa1 PF04114.14 AAAP01003854.1_19 - 0.14 11.1 1.0 0.17 10.9 1.0 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component BatA PF07584.11 AAAP01003854.1_19 - 0.2 12.0 4.5 0.46 10.9 4.5 1.7 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal DAG1 PF05454.11 AAAP01003854.1_19 - 0.29 10.5 0.0 0.4 10.0 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3040 PF11239.8 AAAP01003854.1_19 - 0.31 11.3 0.1 0.31 11.3 0.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3040) DUF4064 PF13273.6 AAAP01003854.1_19 - 1.2 9.5 6.4 0.46 10.8 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) RseC_MucC PF04246.12 AAAP01003854.1_19 - 3.7 7.5 6.5 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Response_reg PF00072.24 AAAP01003854.1_21 - 1.1e-27 96.4 0.5 1.8e-27 95.7 0.5 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003854.1_21 - 1.9e-22 78.5 0.3 4.7e-22 77.3 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003854.1_21 - 1.2e-05 24.8 1.2 1.7e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003854.1_21 - 0.00046 19.6 0.4 0.0013 18.2 0.4 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01003854.1_21 - 0.0028 17.4 0.1 0.008 16.0 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_10 PF04967.12 AAAP01003854.1_21 - 0.0097 15.7 1.0 0.16 11.8 1.0 2.4 1 1 0 1 1 1 1 HTH DNA binding domain HTH_24 PF13412.6 AAAP01003854.1_21 - 0.014 15.0 0.3 0.046 13.3 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 AAAP01003854.1_21 - 0.038 14.4 0.2 0.099 13.1 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain 3HCDH_RFF PF18321.1 AAAP01003854.1_21 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HTH_38 PF13936.6 AAAP01003854.1_21 - 0.12 12.2 0.2 0.29 10.9 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF22 PF01629.16 AAAP01003854.1_21 - 0.34 10.6 1.9 1.4 8.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF22 Nitro_FeMo-Co PF02579.17 AAAP01003854.1_22 - 8e-08 32.5 0.1 1.8e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor MMR_HSR1 PF01926.23 AAAP01003854.1_23 - 2.1e-50 169.6 0.1 1.2e-26 93.1 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 AAAP01003854.1_23 - 2.6e-34 117.4 0.1 4.5e-34 116.6 0.1 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 AAAP01003854.1_23 - 1.5e-28 99.3 0.0 3.4e-13 49.4 0.2 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 AAAP01003854.1_23 - 1e-21 77.4 0.6 9.7e-10 38.3 0.3 5.5 2 2 0 3 3 3 3 Elongation factor Tu GTP binding domain AIG1 PF04548.16 AAAP01003854.1_23 - 1.5e-13 50.6 0.0 1.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 AAAP01003854.1_23 - 1.5e-10 41.4 1.3 0.027 14.5 0.0 4.2 2 2 2 4 4 4 3 Dynamin family RsgA_GTPase PF03193.16 AAAP01003854.1_23 - 5.1e-09 36.3 0.0 0.17 11.8 0.0 3.8 4 0 0 4 4 4 3 RsgA GTPase Ras PF00071.22 AAAP01003854.1_23 - 3e-07 30.2 0.0 0.0049 16.5 0.0 3.0 2 2 0 2 2 2 2 Ras family Roc PF08477.13 AAAP01003854.1_23 - 2.3e-06 27.8 0.0 0.0065 16.7 0.0 3.1 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 AAAP01003854.1_23 - 2.4e-05 23.4 3.7 0.049 12.6 0.6 4.0 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AAAP01003854.1_23 - 0.00013 21.8 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AAAP01003854.1_23 - 0.00045 20.5 0.1 0.82 9.9 0.1 2.8 2 2 0 2 2 2 2 AAA domain ABC_tran PF00005.27 AAAP01003854.1_23 - 0.0005 20.6 0.2 1.6 9.2 0.0 2.8 2 1 0 2 2 2 2 ABC transporter PduV-EutP PF10662.9 AAAP01003854.1_23 - 0.00071 19.3 0.1 5.5 6.7 0.0 3.9 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 AAAP01003854.1_23 - 0.00076 20.0 0.1 1.9 9.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain Septin PF00735.18 AAAP01003854.1_23 - 0.0014 17.9 0.0 0.53 9.5 0.0 2.8 2 1 0 2 2 2 1 Septin SRPRB PF09439.10 AAAP01003854.1_23 - 0.0023 17.4 0.0 1.3 8.4 0.0 2.4 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit TniB PF05621.11 AAAP01003854.1_23 - 0.0033 16.9 0.0 0.62 9.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_29 PF13555.6 AAAP01003854.1_23 - 0.0048 16.6 0.0 3.3 7.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 AAAP01003854.1_23 - 0.02 14.1 0.0 4.1 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 AAAP01003854.1_23 - 0.024 15.0 0.1 11 6.5 0.0 2.6 3 0 0 3 3 2 0 RNA helicase cobW PF02492.19 AAAP01003854.1_23 - 0.043 13.4 2.5 0.14 11.7 0.3 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 AAAP01003854.1_23 - 0.054 13.4 0.1 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 AAAP01003854.1_23 - 0.12 12.6 0.0 12 6.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain PQQ_2 PF13360.6 AAAP01003854.1_24 - 2.6e-68 230.2 9.1 2.3e-60 204.1 5.3 2.8 2 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AAAP01003854.1_24 - 6.6e-37 125.1 9.1 1.4e-05 25.4 0.1 8.3 8 0 0 8 8 8 7 PQQ-like domain PQQ PF01011.21 AAAP01003854.1_24 - 6.6e-26 89.0 1.0 0.00027 20.7 0.0 7.6 7 0 0 7 7 7 5 PQQ enzyme repeat RHS PF03527.14 AAAP01003854.1_24 - 2.2 8.1 4.5 30 4.5 0.0 4.0 5 0 0 5 5 5 0 RHS protein TPR_21 PF09976.9 AAAP01003854.1_25 - 1.6e-16 60.6 12.4 2.3e-16 60.1 12.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 AAAP01003854.1_25 - 4.2e-06 27.3 23.9 0.0031 18.1 4.5 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003854.1_25 - 0.00013 22.1 0.2 0.4 10.9 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PAP_PilO PF06864.12 AAAP01003854.1_25 - 0.0016 17.3 0.4 0.0025 16.7 0.4 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) TPR_19 PF14559.6 AAAP01003854.1_25 - 0.0065 17.0 15.2 1.3 9.6 0.2 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 AAAP01003854.1_25 - 0.031 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 AAAP01003854.1_25 - 0.24 11.6 6.5 24 5.3 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003854.1_25 - 0.36 11.5 10.8 15 6.5 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003854.1_25 - 3.9 8.6 17.6 36 5.6 4.0 4.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003854.1_25 - 5.6 7.9 27.0 0.67 10.7 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 AAAP01003854.1_26 - 7.3e-18 64.7 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01003854.1_26 - 7.7e-13 48.4 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF2794 PF10984.8 AAAP01003854.1_28 - 4.4e-23 81.2 0.0 5.3e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2794) HATPase_c PF02518.26 AAAP01003854.1_30 - 7.1e-19 68.4 0.0 1.6e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003854.1_30 - 3.4e-06 27.0 1.4 2e-05 24.5 0.0 2.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003854.1_30 - 0.0002 21.2 0.0 0.0005 19.9 0.0 1.6 1 1 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01003854.1_30 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TarH PF02203.15 AAAP01003854.1_30 - 0.049 13.6 0.9 3.1 7.7 0.6 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue HATPase_c_2 PF13581.6 AAAP01003854.1_30 - 0.1 12.6 1.5 0.24 11.3 0.0 2.3 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain DUF1043 PF06295.12 AAAP01003854.1_30 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Gram_pos_anchor PF00746.21 AAAP01003854.1_30 - 1.7 8.6 5.1 30 4.7 2.1 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Response_reg PF00072.24 AAAP01003854.1_31 - 8.7e-28 96.7 0.2 1.6e-27 95.9 0.1 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003854.1_31 - 1.8e-24 85.6 0.5 6.9e-23 80.5 0.1 2.6 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAAP01003854.1_31 - 0.0013 18.6 0.4 0.004 17.0 0.4 1.9 1 0 0 1 1 1 1 MarR family DUF983 PF06170.12 AAAP01003854.1_32 - 1.1e-25 89.8 3.6 1.9e-25 89.1 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF983) zf-ribbon_3 PF13248.6 AAAP01003854.1_32 - 0.15 11.5 2.6 11 5.6 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AAAP01003854.1_32 - 7.9 6.6 7.7 9.4 6.3 3.3 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TfoX_N PF04993.13 AAAP01003854.1_33 - 5.5e-29 100.2 0.0 6.4e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 TfoX N-terminal domain OEP PF02321.18 AAAP01003854.1_34 - 9.4e-52 175.6 30.2 2.7e-26 92.5 14.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein CAP-ZIP_m PF15255.6 AAAP01003854.1_34 - 0.0088 16.3 2.0 0.026 14.8 1.9 1.9 1 1 0 1 1 1 1 WASH complex subunit CAP-Z interacting, central region EzrA PF06160.12 AAAP01003854.1_34 - 0.042 12.0 0.1 0.076 11.2 0.1 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Resolvase PF00239.21 AAAP01003854.1_35 - 2.7e-12 47.0 0.1 4.5e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_29 PF13551.6 AAAP01003854.1_35 - 8e-06 25.8 1.2 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn helix HTH_28 PF13518.6 AAAP01003854.1_35 - 2.3e-05 24.4 1.4 5.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 AAAP01003854.1_35 - 9.9e-05 22.0 0.2 0.00028 20.6 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003854.1_35 - 0.00011 21.9 0.6 0.00046 19.9 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AAAP01003854.1_35 - 0.00012 21.5 1.0 0.00055 19.3 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 AAAP01003854.1_35 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 AAAP01003854.1_35 - 0.0024 18.2 0.0 0.0059 16.9 0.0 1.7 2 0 0 2 2 1 1 Transposase HTH_32 PF13565.6 AAAP01003854.1_35 - 0.0031 18.1 0.8 0.0072 16.9 0.8 1.6 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 AAAP01003854.1_35 - 0.017 15.0 3.2 0.019 14.8 1.4 2.1 2 1 0 2 2 2 0 MarR family Trp_repressor PF01371.19 AAAP01003854.1_35 - 0.054 13.6 0.1 0.94 9.7 0.0 2.5 2 1 1 3 3 3 0 Trp repressor protein HTH_30 PF13556.6 AAAP01003854.1_35 - 0.062 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain GerE PF00196.19 AAAP01003854.1_35 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Fe_dep_repress PF01325.19 AAAP01003854.1_35 - 0.16 12.2 0.3 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Microvir_J PF04726.13 AAAP01003854.1_35 - 0.28 11.2 1.3 0.5 10.4 1.3 1.4 1 0 0 1 1 1 0 Microvirus J protein ACR_tran PF00873.19 AAAP01003854.1_36 - 3.2e-32 111.2 2.3 3.6e-32 111.1 2.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ACR_tran PF00873.19 AAAP01003854.1_37 - 2.6e-12 45.3 4.5 2.7e-12 45.3 4.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family ACR_tran PF00873.19 AAAP01003854.1_38 - 1.8e-241 803.9 5.0 2.2e-241 803.7 5.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AAAP01003854.1_38 - 5.4e-05 22.7 16.4 0.00013 21.4 16.4 1.6 1 0 0 1 1 1 1 Protein export membrane protein ACR_tran PF00873.19 AAAP01003854.1_39 - 0 1021.2 17.4 0 1021.0 17.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003854.1_39 - 5.7e-05 22.2 19.8 5.7e-05 22.2 19.8 3.5 3 1 1 4 4 4 1 MMPL family SecD_SecF PF02355.16 AAAP01003854.1_39 - 7e-05 22.3 26.9 0.0011 18.3 15.9 2.8 3 0 0 3 3 3 2 Protein export membrane protein TMEM138 PF14935.6 AAAP01003854.1_39 - 0.67 10.6 4.7 0.56 10.9 0.6 2.6 2 0 0 2 2 2 0 Transmembrane protein 138 FixQ PF05545.11 AAAP01003854.1_39 - 0.7 9.9 4.9 0.59 10.1 0.2 3.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Glyco_transf_9 PF01075.17 AAAP01003855.1_1 - 6.9e-09 35.4 0.0 9.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_9 PF01075.17 AAAP01003855.1_2 - 8.4e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_9 PF01075.17 AAAP01003855.1_3 - 1.6e-17 63.6 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) GYF_2 PF14237.6 AAAP01003855.1_3 - 0.062 13.1 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 GYF domain 2 GlnD_UR_UTase PF08335.11 AAAP01003855.1_4 - 7.8e-35 120.1 0.0 1.4e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase ACT PF01842.25 AAAP01003855.1_4 - 1.4e-09 37.5 0.4 0.00012 21.8 0.0 2.7 2 0 0 2 2 2 2 ACT domain HD PF01966.22 AAAP01003855.1_4 - 3.4e-08 33.7 0.2 4.1e-07 30.2 0.0 2.8 2 1 1 3 3 3 1 HD domain ACT_6 PF13740.6 AAAP01003855.1_4 - 8.6e-08 32.1 0.1 0.023 14.7 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 AAAP01003855.1_4 - 1.9e-06 28.4 0.1 0.0054 17.3 0.0 2.6 2 0 0 2 2 2 2 ACT domain NTP_transf_2 PF01909.23 AAAP01003855.1_4 - 1.1e-05 25.6 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain GlnE PF03710.15 AAAP01003855.1_4 - 0.0033 16.9 0.0 0.0076 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutamate-ammonia ligase adenylyltransferase CobA_CobO_BtuR PF02572.15 AAAP01003855.1_5 - 4.8e-63 212.5 0.1 7e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Co_AT_N PF12557.8 AAAP01003855.1_5 - 0.00018 21.3 8.6 0.00033 20.5 8.6 1.5 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal AAA_25 PF13481.6 AAAP01003855.1_5 - 0.0081 15.8 2.9 0.021 14.4 2.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01003855.1_5 - 0.13 12.0 3.9 0.3 10.8 3.9 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AAAP01003855.1_6 - 1.5e-29 103.2 0.0 2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003855.1_6 - 2e-11 44.2 0.0 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003855.1_6 - 2.9e-06 26.9 0.0 0.0049 16.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AAAP01003855.1_6 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAAP01003855.1_6 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01003855.1_6 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AAAP01003855.1_6 - 0.0027 17.5 0.0 0.0064 16.3 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 AAAP01003855.1_6 - 0.0036 17.7 0.1 0.0069 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAAP01003855.1_6 - 0.0063 16.1 0.1 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAAP01003855.1_6 - 0.0081 16.7 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AAAP01003855.1_6 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 AAAP01003855.1_6 - 0.027 14.6 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003855.1_6 - 0.073 13.5 0.2 1.7 9.1 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01003855.1_6 - 0.1 12.3 0.1 0.69 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAAP01003855.1_6 - 0.12 12.2 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 AAAP01003855.1_6 - 0.14 12.7 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003855.1_6 - 0.18 11.5 0.1 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 AAAP01003855.1_6 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PhoU PF01895.19 AAAP01003855.1_7 - 2.4e-36 124.1 8.7 5.5e-19 68.4 2.0 2.1 2 0 0 2 2 2 2 PhoU domain IclR PF01614.18 AAAP01003855.1_7 - 0.058 13.2 0.1 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 Bacterial transcriptional regulator PHO4 PF01384.20 AAAP01003855.1_8 - 2.9e-86 289.6 41.0 1.1e-85 287.7 41.0 1.7 1 1 0 1 1 1 1 Phosphate transporter family PhoU_div PF01865.16 AAAP01003855.1_9 - 3.7e-35 121.2 4.0 4.2e-35 121.0 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 Rogdi_lz PF10259.9 AAAP01003855.1_9 - 0.051 13.0 0.0 0.077 12.4 0.0 1.3 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein DUF4872 PF16169.5 AAAP01003855.1_9 - 0.057 13.2 0.1 0.36 10.6 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4872) DUF2524 PF10732.9 AAAP01003855.1_9 - 0.1 12.9 0.1 0.81 10.0 0.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2524) Metal_resist PF13801.6 AAAP01003855.1_9 - 0.51 10.5 7.0 3.6 7.8 0.1 3.1 3 0 0 3 3 3 0 Heavy-metal resistance Methyltransf_4 PF02390.17 AAAP01003855.1_10 - 1.3e-40 138.7 0.0 1.6e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 AAAP01003855.1_10 - 0.017 15.8 0.0 0.23 12.1 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003855.1_10 - 0.069 13.9 0.0 0.19 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003855.1_10 - 0.13 13.1 0.0 0.41 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain S-AdoMet_synt_C PF02773.16 AAAP01003855.1_11 - 9.9e-64 213.5 0.1 4.6e-63 211.3 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AAAP01003855.1_11 - 3.5e-38 130.5 0.0 6.4e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AAAP01003855.1_11 - 8.2e-37 125.9 0.1 6.4e-36 123.0 0.0 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain HTH_3 PF01381.22 AAAP01003855.1_12 - 3e-11 43.2 0.1 6.2e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003855.1_12 - 2.1e-08 34.4 0.3 5.6e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003855.1_12 - 5.1e-05 23.2 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003855.1_12 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CN_hydrolase PF00795.22 AAAP01003855.1_13 - 2.2e-22 79.7 0.0 3.9e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 AAAP01003855.1_13 - 0.091 12.5 1.0 0.38 10.6 1.0 2.1 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal CorC_HlyC PF03471.17 AAAP01003855.1_14 - 1.7e-17 63.2 2.3 5.7e-17 61.5 0.2 2.4 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AAAP01003855.1_14 - 9.4e-11 42.0 9.6 2.9e-05 24.4 0.2 3.4 2 1 1 3 3 3 3 CBS domain PT-VENN PF04829.13 AAAP01003855.1_14 - 0.099 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif UPF0054 PF02130.17 AAAP01003855.1_15 - 5.6e-36 123.2 0.0 6.5e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PhoH PF02562.16 AAAP01003855.1_16 - 6.7e-89 296.8 0.0 8.7e-89 296.4 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AAAP01003855.1_16 - 4.1e-08 33.2 0.0 8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AAAP01003855.1_16 - 7e-06 26.4 0.1 2.5e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 AAAP01003855.1_16 - 0.00037 20.1 0.5 0.043 13.3 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain KH_1 PF00013.29 AAAP01003855.1_16 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 KH domain Secretin_N PF03958.17 AAAP01003855.1_16 - 0.0088 16.4 0.2 0.13 12.7 0.1 2.7 2 1 1 3 3 3 1 Bacterial type II/III secretion system short domain DEAD PF00270.29 AAAP01003855.1_16 - 0.023 14.5 0.1 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 AAAP01003855.1_16 - 0.052 13.1 1.1 0.091 12.3 0.4 1.9 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AAAP01003855.1_16 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 AAAP01003855.1_16 - 0.059 13.6 0.1 9.9 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pro_Al_protease PF02983.14 AAAP01003855.1_16 - 0.077 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Radical_SAM PF04055.21 AAAP01003855.1_17 - 4.1e-29 102.1 0.0 1e-28 100.8 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 AAAP01003855.1_17 - 3.3e-23 81.6 0.0 5.2e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AAAP01003855.1_17 - 3.7e-10 39.6 0.0 7.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 AAAP01003855.1_17 - 0.026 14.7 0.0 0.075 13.2 0.0 1.8 1 1 0 1 1 1 0 TRAM domain B12-binding PF02310.19 AAAP01003855.1_17 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Acyltransferase PF01553.21 AAAP01003855.1_18 - 1.1e-19 70.4 0.0 1.5e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acetyltransf_5 PF13444.6 AAAP01003855.1_19 - 4.9e-32 110.6 0.0 7.7e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyl-CoA_dh_2 PF08028.11 AAAP01003855.1_19 - 0.065 13.5 0.7 0.11 12.7 0.7 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acetyltransf_9 PF13527.7 AAAP01003855.1_19 - 0.14 12.3 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FUR PF01475.19 AAAP01003855.1_20 - 6.4e-40 136.0 0.2 7.3e-40 135.9 0.2 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family RepL PF05732.11 AAAP01003855.1_20 - 0.00026 20.5 0.0 0.085 12.3 0.0 2.1 2 0 0 2 2 2 2 Firmicute plasmid replication protein (RepL) TPR_14 PF13428.6 AAAP01003855.1_20 - 0.13 13.1 0.1 0.77 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_23 PF13384.6 AAAP01003855.1_20 - 0.15 11.9 0.9 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain ROS_MUCR PF05443.11 AAAP01003855.1_21 - 1.5e-50 170.4 0.0 1.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein TusA PF01206.17 AAAP01003855.1_22 - 1e-16 60.5 0.0 1.2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA Acetyltransf_1 PF00583.25 AAAP01003855.1_23 - 1.8e-11 44.3 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AAAP01003855.1_23 - 1.4e-07 31.9 0.0 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AAAP01003855.1_23 - 4.1e-07 30.0 0.0 4.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AAAP01003855.1_23 - 4e-06 26.7 0.0 1.8e-05 24.6 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein PanZ PF12568.8 AAAP01003855.1_23 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 AAAP01003855.1_23 - 0.02 14.8 0.0 0.055 13.5 0.0 1.7 1 1 1 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 AAAP01003855.1_23 - 0.043 13.9 0.0 0.08 13.1 0.0 1.4 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AAAP01003855.1_23 - 0.07 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01003855.1_23 - 0.082 13.6 0.0 0.091 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M22 PF00814.25 AAAP01003855.1_24 - 4.3e-21 75.8 0.9 7.7e-21 75.0 0.9 1.3 1 0 0 1 1 1 1 Glycoprotease family Peptidase_M15 PF01427.17 AAAP01003855.1_25 - 6.1e-36 124.1 0.0 1.1e-35 123.2 0.0 1.3 1 1 0 1 1 1 1 D-ala-D-ala dipeptidase VanY PF02557.17 AAAP01003855.1_25 - 0.00024 20.9 0.6 0.00074 19.3 0.0 2.1 2 1 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_4 PF13539.6 AAAP01003855.1_25 - 0.0079 16.7 0.7 0.62 10.6 0.7 2.9 2 1 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase FMN_dh PF01070.18 AAAP01003855.1_26 - 1e-116 389.8 0.1 1.1e-116 389.7 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AAAP01003855.1_26 - 0.00038 19.6 1.7 0.00094 18.3 1.7 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 AAAP01003855.1_26 - 0.017 14.3 0.6 0.033 13.3 0.3 1.6 1 1 1 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 AAAP01003855.1_26 - 0.034 13.4 0.4 0.053 12.7 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1485 PF07364.12 AAAP01003855.1_26 - 0.042 13.1 0.1 0.083 12.1 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase family M81 His_biosynth PF00977.21 AAAP01003855.1_26 - 0.046 13.2 0.2 0.16 11.4 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 AAAP01003855.1_26 - 0.28 10.3 0.0 0.4 9.8 0.0 1.1 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DUF825 PF05695.12 AAAP01003855.1_27 - 0.16 9.1 0.0 0.2 8.7 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Zn_peptidase PF04228.13 AAAP01003855.1_27 - 0.21 11.0 0.1 0.31 10.4 0.1 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Endonuclease_NS PF01223.23 AAAP01003855.1_28 - 5.4e-29 101.6 0.0 6.8e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease NTP_transferase PF00483.23 AAAP01003855.1_29 - 8.4e-28 97.6 0.0 1e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003855.1_29 - 3.5e-09 37.2 1.1 9.8e-09 35.8 1.1 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003855.1_29 - 0.021 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ChaC PF04752.12 AAAP01003855.1_30 - 1.6e-34 119.5 0.0 1.7e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 AAAP01003855.1_30 - 9.9e-05 22.9 0.0 0.00014 22.5 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2125 PF09898.9 AAAP01003855.1_31 - 2.5e-55 188.4 11.7 3e-55 188.1 11.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2125) Aminotran_5 PF00266.19 AAAP01003855.1_32 - 4.6e-38 131.1 0.0 5.5e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAAP01003855.1_32 - 0.11 11.8 3.2 0.08 12.2 1.7 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family RelB PF04221.12 AAAP01003856.1_1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 RelB antitoxin DUF4149 PF13664.6 AAAP01003856.1_1 - 0.069 13.5 1.1 0.069 13.5 1.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) sCache_3_3 PF17202.4 AAAP01003856.1_2 - 7.9e-34 116.3 2.5 1.1e-33 115.8 0.2 2.4 2 0 0 2 2 2 1 Single cache domain 3 Cache_3-Cache_2 PF17201.4 AAAP01003856.1_2 - 1.2e-30 106.8 1.0 1.2e-30 106.8 1.0 2.6 3 1 0 3 3 3 1 Cache 3/Cache 2 fusion domain MCPsignal PF00015.21 AAAP01003856.1_2 - 1.4e-30 106.4 45.4 5.4e-30 104.4 25.9 2.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_3_2 PF17203.4 AAAP01003856.1_2 - 1.1e-14 54.7 0.1 1.1e-14 54.7 0.1 3.3 3 1 0 3 3 3 1 Single cache domain 3 HAMP PF00672.25 AAAP01003856.1_2 - 3.5e-08 33.7 0.1 3.5e-08 33.7 0.1 3.5 4 0 0 4 4 4 1 HAMP domain DUF1664 PF07889.12 AAAP01003856.1_2 - 0.016 15.2 10.5 0.87 9.6 2.2 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Imm51 PF15595.6 AAAP01003856.1_2 - 0.033 14.1 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 Immunity protein 51 CENP-F_leu_zip PF10473.9 AAAP01003856.1_2 - 0.25 11.4 4.1 0.15 12.1 1.1 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA1 PF07160.12 AAAP01003856.1_2 - 0.86 9.4 5.4 0.45 10.3 0.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Mur_ligase_C PF02875.21 AAAP01003856.1_2 - 1.1 9.6 5.8 0.99 9.7 0.1 3.5 2 2 1 3 3 3 0 Mur ligase family, glutamate ligase domain Laminin_II PF06009.12 AAAP01003856.1_2 - 2.4 8.2 22.1 0.55 10.3 2.0 3.7 1 1 2 3 3 3 0 Laminin Domain II dCache_1 PF02743.18 AAAP01003856.1_2 - 8.2 6.1 10.7 1.4 8.7 0.0 3.4 2 1 1 4 4 4 0 Cache domain Spc7 PF08317.11 AAAP01003856.1_2 - 9.5 5.0 11.8 4 6.2 5.6 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Fer4_6 PF12837.7 AAAP01003856.1_3 - 3.7e-14 52.1 33.1 0.0002 21.3 0.8 4.2 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003856.1_3 - 1.4e-13 51.2 28.4 1.8e-05 25.2 12.1 3.6 2 1 3 5 5 5 5 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003856.1_3 - 1.1e-12 48.0 28.7 5.6e-06 26.4 10.5 2.7 1 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003856.1_3 - 1.9e-12 46.4 39.9 0.00014 21.5 5.2 5.6 4 2 0 4 4 4 4 4Fe-4S binding domain Fer4_11 PF13247.6 AAAP01003856.1_3 - 3.6e-12 46.3 12.6 3.6e-12 46.3 12.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003856.1_3 - 1.1e-10 41.5 31.4 4.7e-06 26.6 12.8 3.2 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003856.1_3 - 1.9e-10 40.7 27.7 1.1e-07 31.9 11.9 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003856.1_3 - 1.6e-09 38.6 27.8 0.015 16.3 1.1 4.3 2 1 2 4 4 4 4 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AAAP01003856.1_3 - 1.4e-08 34.4 32.6 0.0013 18.7 3.2 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003856.1_3 - 3e-08 33.5 35.0 0.00072 19.9 3.1 4.2 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003856.1_3 - 5.5e-05 23.8 43.2 0.041 14.8 5.3 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003856.1_3 - 7.4e-05 23.1 28.1 0.0019 18.6 8.7 3.2 2 1 3 5 5 4 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003856.1_3 - 0.00038 20.9 30.1 0.79 10.3 4.6 4.0 1 1 4 5 5 5 4 4Fe-4S dicluster domain ETF_QO PF05187.13 AAAP01003856.1_3 - 0.04 14.0 12.8 0.047 13.8 3.6 3.1 1 1 2 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_15 PF13459.6 AAAP01003856.1_3 - 0.074 13.8 22.8 0.59 10.9 9.0 3.8 3 1 0 3 3 3 0 4Fe-4S single cluster domain AFOR_C PF01314.18 AAAP01003856.1_4 - 3.3e-132 441.1 0.3 4.5e-132 440.7 0.3 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 AAAP01003856.1_4 - 2.6e-79 265.7 0.4 2.6e-79 265.7 0.4 1.6 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Pyr_redox_2 PF07992.14 AAAP01003856.1_5 - 2.1e-52 178.2 0.2 2.7e-52 177.8 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003856.1_5 - 1.4e-12 48.0 0.2 1e-08 35.6 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01003856.1_5 - 1.1e-06 28.7 2.1 0.29 11.1 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AAAP01003856.1_5 - 0.00011 22.4 0.1 0.53 10.5 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AAAP01003856.1_5 - 0.0012 17.7 0.0 1.8 7.2 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 AAAP01003856.1_5 - 0.0036 16.4 1.9 0.92 8.5 0.2 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AAAP01003856.1_5 - 0.0039 16.5 0.1 0.55 9.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAAP01003856.1_5 - 0.0083 15.0 0.1 0.94 8.2 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase ThiF PF00899.21 AAAP01003856.1_5 - 0.15 11.4 0.6 0.59 9.5 0.1 2.1 2 0 0 2 2 2 0 ThiF family Slx4 PF09494.10 AAAP01003856.1_5 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Slx4 endonuclease Sacchrp_dh_NADP PF03435.18 AAAP01003856.1_5 - 0.24 11.6 1.0 1 9.7 0.6 2.2 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 AAAP01003856.1_6 - 2.3e-47 161.7 0.0 2.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003856.1_6 - 8.6e-11 42.3 0.3 1.7e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003856.1_6 - 3e-09 36.6 0.0 1.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AAAP01003856.1_6 - 3.5e-09 36.8 0.8 0.029 14.4 0.0 4.0 5 0 0 5 5 5 3 FAD-NAD(P)-binding HI0933_like PF03486.14 AAAP01003856.1_6 - 2.7e-06 26.3 0.3 0.028 13.1 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Rubredoxin_C PF18267.1 AAAP01003856.1_6 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_8 PF13450.6 AAAP01003856.1_6 - 0.00025 21.2 1.2 0.0052 17.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AAAP01003856.1_6 - 0.00074 18.5 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 AAAP01003856.1_6 - 0.00097 18.3 0.4 0.076 12.1 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 AAAP01003856.1_6 - 0.0016 18.1 9.7 0.052 13.1 0.4 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AAAP01003856.1_6 - 0.0024 18.3 0.2 0.69 10.4 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AAAP01003856.1_6 - 0.0079 16.5 0.6 6.6 7.0 0.0 3.0 2 1 1 3 3 3 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 AAAP01003856.1_6 - 0.011 14.9 0.6 0.86 8.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 AAAP01003856.1_6 - 0.044 12.9 0.0 0.87 8.7 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) CZB PF13682.6 AAAP01003856.1_6 - 0.11 12.9 0.0 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain Reductase_C PF14759.6 AAAP01003856.1_6 - 0.13 12.9 0.0 0.45 11.1 0.0 2.0 1 0 0 1 1 1 0 Reductase C-terminal Amino_oxidase PF01593.24 AAAP01003856.1_6 - 0.14 11.4 0.1 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 AAAP01003856.1_6 - 0.2 11.7 0.7 0.75 9.9 0.0 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ThiS PF02597.20 AAAP01003856.1_7 - 1.3e-09 38.5 0.0 1.6e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 ThiS family Ub-Mut7C PF14451.6 AAAP01003856.1_7 - 0.00078 19.2 0.0 0.00098 18.9 0.0 1.1 1 0 0 1 1 1 1 Mut7-C ubiquitin GntR PF00392.21 AAAP01003856.1_9 - 1.7e-13 50.0 0.0 2.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 AAAP01003856.1_9 - 7.9e-07 29.5 0.3 3.1e-06 27.6 0.1 2.1 2 1 0 2 2 2 1 FCD domain TPR_2 PF07719.17 AAAP01003856.1_10 - 1.5e-27 93.4 13.8 2.9e-08 33.2 0.1 7.6 8 1 1 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003856.1_10 - 1.2e-26 91.4 4.6 1.3e-09 37.5 0.0 7.2 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003856.1_10 - 4e-25 87.2 3.3 1.1e-08 34.6 0.1 7.3 6 1 1 7 7 7 5 TPR repeat TPR_8 PF13181.6 AAAP01003856.1_10 - 1.2e-22 78.1 0.1 2.9e-06 27.1 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003856.1_10 - 1.9e-22 79.7 32.5 1.2e-08 35.5 0.8 4.9 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003856.1_10 - 3e-17 62.7 38.7 2.9e-07 30.7 5.8 5.2 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003856.1_10 - 3.5e-17 61.6 34.7 6.3e-05 23.5 0.2 7.8 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003856.1_10 - 2.8e-16 58.7 3.0 0.29 11.6 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003856.1_10 - 1.3e-13 49.9 7.4 0.0099 15.8 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003856.1_10 - 3.2e-12 46.8 23.9 0.0015 19.0 0.5 5.8 1 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003856.1_10 - 5e-11 42.1 32.7 3e-05 23.7 0.8 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003856.1_10 - 2.5e-05 24.3 23.2 0.0015 18.7 0.8 4.5 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003856.1_10 - 2.5e-05 23.6 13.7 0.0045 16.2 4.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003856.1_10 - 2.6e-05 24.5 8.2 0.23 12.2 0.1 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 AAAP01003856.1_10 - 5.4e-05 22.6 0.2 0.00013 21.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) ANAPC3 PF12895.7 AAAP01003856.1_10 - 0.0002 21.5 0.1 0.46 10.8 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 AAAP01003856.1_10 - 0.0031 18.0 1.5 0.0031 18.0 1.5 8.1 8 1 0 8 8 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 AAAP01003856.1_10 - 0.006 16.0 0.2 0.68 9.3 0.0 2.6 2 1 1 3 3 3 1 Coatomer epsilon subunit OEP PF02321.18 AAAP01003856.1_11 - 1.7e-52 177.9 8.6 1e-26 93.9 1.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Phosphorylase PF00343.20 AAAP01003856.1_12 - 0 1070.1 0.0 0 1069.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Glyco_hydro_77 PF02446.17 AAAP01003856.1_13 - 5.9e-11 41.9 0.0 6.5e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Glyco_hydro_77 PF02446.17 AAAP01003856.1_14 - 4.4e-107 358.8 0.0 5.4e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_48 PF02922.18 AAAP01003856.1_15 - 3e-20 72.3 0.0 6.6e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 AAAP01003856.1_15 - 1.2e-13 51.4 0.1 7.7e-09 35.6 0.2 3.1 2 1 0 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 AAAP01003856.1_16 - 2.1e-28 98.5 0.0 3e-22 78.8 0.0 2.7 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 AAAP01003856.1_16 - 8.7e-19 67.8 0.0 2.6e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 AAAP01003856.1_16 - 2.9e-12 46.8 0.0 2.8e-06 27.2 0.0 2.3 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 AAAP01003856.1_16 - 0.033 12.4 0.0 0.05 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 AMPK1_CBM PF16561.5 AAAP01003856.1_16 - 0.12 12.7 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase LPAM_1 PF08139.12 AAAP01003856.1_17 - 0.12 12.9 1.5 0.34 11.5 1.5 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site 5_3_exonuc_N PF02739.16 AAAP01003856.1_18 - 0.074 13.0 0.1 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Ferric_reduct PF01794.19 AAAP01003856.1_19 - 4.9e-18 65.5 6.7 8.9e-18 64.6 6.7 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Oxidored_molyb PF00174.19 AAAP01003856.1_20 - 1.8e-29 102.6 0.0 2.6e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TAT_signal PF10518.9 AAAP01003856.1_20 - 0.75 9.7 4.6 1.3 9.0 4.6 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Peptidase_M48 PF01435.18 AAAP01003856.1_21 - 5.5e-25 88.3 0.1 1.1e-24 87.4 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M48 DUF4157 PF13699.6 AAAP01003856.1_21 - 0.0012 19.0 1.1 0.0091 16.2 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4157) BSP PF04450.12 AAAP01003856.1_21 - 0.071 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria DUF898 PF05987.13 AAAP01003856.1_22 - 2.4e-78 263.6 17.9 2.7e-78 263.4 17.9 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Pox_A14 PF05767.12 AAAP01003856.1_22 - 0.17 12.1 0.8 1.6 9.0 0.1 2.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PrgI PF12666.7 AAAP01003856.1_22 - 1.7 9.4 11.5 0.46 11.2 1.6 2.9 3 0 0 3 3 3 0 PrgI family protein ADH_zinc_N PF00107.26 AAAP01003856.1_23 - 6.2e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AAAP01003856.1_23 - 5.6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 AAAP01003856.1_23 - 0.0049 17.9 0.0 0.0084 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 AAAP01003856.1_23 - 0.011 15.6 0.1 0.15 12.0 0.1 2.5 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase adh_short PF00106.25 AAAP01003856.1_23 - 0.03 13.8 0.3 0.056 12.9 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase SBF PF01758.16 AAAP01003856.1_24 - 8.9e-31 107.1 7.8 8.9e-31 107.1 7.8 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 AAAP01003856.1_24 - 4.1e-19 69.0 17.9 4.6e-19 68.9 17.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 AAAP01003856.1_24 - 0.0002 19.9 12.6 0.0002 19.9 12.6 2.0 2 1 0 2 2 2 1 Membrane transport protein Anophelin PF10731.9 AAAP01003856.1_24 - 0.1 12.4 0.4 0.1 12.4 0.4 2.1 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito OAD_beta PF03977.13 AAAP01003856.1_24 - 1 8.3 19.6 0.025 13.6 6.9 2.5 2 1 0 2 2 2 0 Na+-transporting oxaloacetate decarboxylase beta subunit UbiA PF01040.18 AAAP01003856.1_25 - 2.8e-35 121.8 22.6 3.6e-35 121.5 22.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Acyl_transf_3 PF01757.22 AAAP01003856.1_25 - 2.1 7.3 17.9 3.8 6.5 11.0 2.2 1 1 1 2 2 2 0 Acyltransferase family Ubie_methyltran PF01209.18 AAAP01003856.1_26 - 1.9e-70 236.8 0.0 2.3e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AAAP01003856.1_26 - 1.9e-19 70.1 0.0 2.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003856.1_26 - 4.7e-18 65.7 0.0 1.1e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003856.1_26 - 5.9e-12 45.7 0.0 7.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003856.1_26 - 7.2e-09 35.6 0.0 9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003856.1_26 - 3e-08 34.3 0.0 4.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAAP01003856.1_26 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 AAAP01003856.1_26 - 0.19 11.6 0.0 0.44 10.3 0.0 1.7 2 1 0 2 2 2 0 Hypothetical methyltransferase ABC2_membrane_2 PF12679.7 AAAP01003856.1_27 - 1.6e-18 67.0 21.7 5.3e-18 65.3 21.7 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAAP01003856.1_27 - 1.4e-09 37.7 21.9 2.4e-09 36.9 21.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01003856.1_27 - 5.1e-09 35.7 19.5 5.1e-09 35.7 19.5 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAAP01003856.1_27 - 0.00091 19.2 11.7 0.00091 19.2 11.7 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein NosL PF05573.12 AAAP01003856.1_28 - 0.00022 21.6 0.0 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 NosL UCR_Fe-S_N PF10399.9 AAAP01003856.1_28 - 0.079 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ABC_tran PF00005.27 AAAP01003856.1_29 - 3.4e-23 82.7 0.0 6.2e-23 81.8 0.0 1.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003856.1_29 - 2.2e-11 44.1 0.1 9.6e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003856.1_29 - 6.7e-08 32.2 0.0 9.4e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 AAAP01003856.1_29 - 8.1e-06 25.7 0.2 0.011 15.5 0.1 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 AAAP01003856.1_29 - 0.00032 20.5 0.1 0.0014 18.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003856.1_29 - 0.0019 18.6 0.2 0.0039 17.6 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 AAAP01003856.1_29 - 0.0038 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 AAAP01003856.1_29 - 0.0044 16.2 0.8 0.073 12.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 AAAP01003856.1_29 - 0.0063 16.3 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 AAAP01003856.1_29 - 0.0072 16.9 0.0 0.01 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003856.1_29 - 0.0073 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase DUF3584 PF12128.8 AAAP01003856.1_29 - 0.015 12.9 0.1 0.021 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 AAAP01003856.1_29 - 0.016 15.3 0.4 0.037 14.1 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AAAP01003856.1_29 - 0.019 15.2 0.5 0.093 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AAAP01003856.1_29 - 0.021 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 AAAP01003856.1_29 - 0.023 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AAAP01003856.1_29 - 0.052 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003856.1_29 - 0.059 13.5 0.1 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AAAP01003856.1_29 - 0.066 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 AAAP01003856.1_29 - 0.092 12.3 0.6 0.18 11.4 0.2 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 AAAP01003856.1_29 - 0.096 12.6 1.4 0.32 10.9 0.1 2.1 2 1 0 2 2 2 0 NTPase ATP-synt_ab PF00006.25 AAAP01003856.1_29 - 0.1 12.3 0.1 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 AAAP01003856.1_29 - 0.12 12.6 0.5 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AAAP01003856.1_29 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 AAAP01003856.1_29 - 0.15 12.5 0.3 0.6 10.5 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 AAAP01003856.1_29 - 0.17 11.4 2.2 1.1 8.8 0.1 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B Fer4_5 PF12801.7 AAAP01003856.1_30 - 2.5e-10 40.2 13.6 9.7e-09 35.1 1.5 3.1 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003856.1_30 - 1.2e-05 25.8 9.5 0.015 15.8 2.0 3.4 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003856.1_30 - 1.2e-05 24.9 2.2 1.2e-05 24.9 2.2 3.3 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003856.1_30 - 0.00097 19.3 9.6 0.2 11.8 10.3 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003856.1_30 - 0.0013 18.7 3.1 0.0013 18.7 3.1 3.8 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003856.1_30 - 0.0018 19.1 0.9 0.0018 19.1 0.9 3.4 5 0 0 5 5 4 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003856.1_30 - 0.0031 17.6 7.9 0.0031 17.6 7.9 2.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003856.1_30 - 0.0097 16.0 2.7 0.0097 16.0 2.7 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003856.1_30 - 0.012 15.7 2.5 0.012 15.7 2.5 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003856.1_30 - 0.017 15.6 3.3 0.017 15.6 3.3 3.6 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003856.1_30 - 0.019 15.4 0.7 0.019 15.4 0.7 3.5 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003856.1_30 - 0.03 15.2 3.4 0.03 15.2 3.4 4.0 4 0 0 4 4 4 0 4Fe-4S binding domain DUF3493 PF11998.8 AAAP01003856.1_30 - 0.046 13.9 3.6 0.86 9.8 0.1 2.4 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Fer4_19 PF06902.11 AAAP01003856.1_30 - 0.05 13.7 2.2 0.1 12.7 2.2 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_18 PF13746.6 AAAP01003856.1_30 - 0.12 12.6 9.8 1.3 9.2 8.3 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Nodulin_late PF07127.11 AAAP01003856.1_30 - 0.31 11.4 0.1 0.31 11.4 0.1 2.2 2 0 0 2 2 2 0 Late nodulin protein Fer4_17 PF13534.6 AAAP01003856.1_30 - 0.61 10.7 14.6 0.52 10.9 2.6 3.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003856.1_31 - 1.8e-14 52.8 33.0 2.2e-06 27.2 5.4 4.5 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003856.1_31 - 2.6e-14 53.9 17.3 0.00011 23.1 1.5 3.9 3 1 0 3 3 3 3 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01003856.1_31 - 3.8e-14 53.0 23.5 5.1e-08 33.4 8.6 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003856.1_31 - 3.4e-13 49.5 15.6 1.5e-05 25.1 0.0 3.5 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003856.1_31 - 9.6e-12 44.5 34.1 0.00044 20.2 3.1 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003856.1_31 - 4.5e-10 39.5 26.3 8.9e-05 22.5 1.7 3.8 3 1 1 4 4 4 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003856.1_31 - 8.1e-09 35.3 29.6 0.0026 18.2 3.3 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_8 PF13183.6 AAAP01003856.1_31 - 4.1e-06 27.1 19.5 0.0014 19.0 0.0 3.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003856.1_31 - 4.4e-06 26.7 28.1 0.0045 17.1 10.9 3.5 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003856.1_31 - 4.4e-06 27.2 42.2 0.00091 20.0 6.6 4.5 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003856.1_31 - 3.6e-05 23.6 31.1 0.0043 17.1 2.3 4.5 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003856.1_31 - 0.00025 21.5 24.8 0.0083 16.6 0.8 4.2 3 2 0 3 3 3 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AAAP01003856.1_31 - 0.0013 19.5 16.8 0.082 13.8 1.6 3.5 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AAAP01003856.1_31 - 0.0016 18.6 21.0 0.052 13.8 3.4 4.0 3 1 0 4 4 4 2 4Fe-4S dicluster domain NosD PF05048.13 AAAP01003856.1_32 - 4.3e-50 170.2 18.4 1.8e-46 158.3 13.7 2.1 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 AAAP01003856.1_32 - 3.2e-33 114.8 26.0 8.5e-23 80.9 9.2 2.1 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 AAAP01003856.1_32 - 5.1e-06 26.0 8.4 0.012 14.9 2.1 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) Pectate_lyase_3 PF12708.7 AAAP01003856.1_32 - 0.00021 21.2 7.9 0.064 13.1 5.1 3.2 1 1 1 2 2 2 2 Pectate lyase superfamily protein DUF2502 PF10697.9 AAAP01003856.1_32 - 1.1 9.6 7.5 0.47 10.9 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) TMEM125 PF15109.6 AAAP01003856.1_33 - 0.012 16.0 0.1 0.023 15.1 0.1 1.5 1 0 0 1 1 1 0 TMEM125 protein family IF-2B PF01008.17 AAAP01003857.1_1 - 6.6e-53 179.7 0.0 8.3e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family HAP2-GCS1 PF10699.9 AAAP01003857.1_1 - 0.022 14.7 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 Male gamete fusion factor TRAM PF01938.20 AAAP01003857.1_1 - 0.11 12.6 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 TRAM domain DUF4351 PF14261.6 AAAP01003857.1_3 - 0.18 11.9 77.3 0.5 10.5 0.1 25.5 15 10 10 27 27 27 0 Domain of unknown function (DUF4351) ATHILA PF03078.15 AAAP01003857.1_3 - 0.28 9.9 8.3 0.15 10.9 0.1 4.2 2 1 1 3 3 3 0 ATHILA ORF-1 family BON PF04972.17 AAAP01003857.1_4 - 7.4e-19 67.8 7.0 2.8e-09 37.2 0.6 2.4 3 0 0 3 3 3 2 BON domain SNARE_assoc PF09335.11 AAAP01003857.1_5 - 7.4e-21 74.9 10.0 7.4e-21 74.9 10.0 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF418 PF04235.12 AAAP01003857.1_5 - 0.059 13.3 5.3 1 9.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF418) PA28_alpha PF02251.18 AAAP01003857.1_5 - 0.098 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit RseC_MucC PF04246.12 AAAP01003857.1_5 - 4.2 7.3 6.6 4.4 7.3 0.8 2.6 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 AAAP01003857.1_5 - 7.2 5.3 6.7 0.36 9.5 1.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Glycos_transf_2 PF00535.26 AAAP01003857.1_6 - 2e-23 83.0 0.0 3.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003857.1_6 - 1.5e-10 41.4 0.1 2e-10 41.0 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003857.1_6 - 0.00042 19.9 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003857.1_6 - 0.027 15.0 0.0 0.054 14.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 ACCA PF03255.14 AAAP01003857.1_7 - 3.8e-62 208.4 0.0 5.3e-62 207.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AAAP01003857.1_7 - 4e-20 71.9 0.1 4.7e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAAP01003857.1_7 - 3.8e-08 33.1 0.5 5.3e-08 32.6 0.5 1.1 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 AAAP01003857.1_7 - 0.12 11.7 0.2 0.35 10.1 0.2 1.7 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ABC_tran_CTD PF16326.5 AAAP01003857.1_7 - 0.15 12.3 0.2 0.79 10.0 0.1 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Hydrolase_4 PF12146.8 AAAP01003857.1_8 - 1.1e-14 54.3 0.4 5.7e-10 38.9 0.2 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003857.1_8 - 1.4e-08 34.7 0.2 7.4e-05 22.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003857.1_8 - 6.5e-07 30.2 5.7 5.6e-06 27.1 2.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family AXE1 PF05448.12 AAAP01003857.1_8 - 1.9e-06 26.8 0.0 0.049 12.3 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 AAAP01003857.1_8 - 0.00023 21.1 1.0 0.00053 19.9 0.5 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AAAP01003857.1_8 - 0.0042 16.6 1.3 2.7 7.4 1.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AAAP01003857.1_8 - 0.0047 16.5 0.1 0.02 14.5 0.1 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 AAAP01003857.1_8 - 0.04 13.7 0.0 11 5.8 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.18 AAAP01003857.1_8 - 0.18 11.3 0.0 1 8.9 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 AAAP01003857.1_8 - 0.22 11.4 0.0 0.75 9.7 0.1 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.12 AAAP01003857.1_8 - 0.24 10.4 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) AMP-binding PF00501.28 AAAP01003857.1_9 - 1.8e-94 316.8 0.1 2.2e-94 316.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003857.1_9 - 5.1e-25 88.2 0.0 9.6e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AAAP01003857.1_9 - 1.1e-20 73.2 0.9 2.5e-20 72.2 0.9 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Rieske PF00355.26 AAAP01003857.1_10 - 1.5e-08 34.5 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAAP01003857.1_10 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 Rieske-like [2Fe-2S] domain EVE PF01878.18 AAAP01003857.1_13 - 3.2e-47 160.2 0.0 3.6e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 EVE domain YCII PF03795.14 AAAP01003857.1_14 - 2e-16 60.2 0.0 2.2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF4337 PF14235.6 AAAP01003857.1_15 - 1.6e-42 145.3 1.9 2.3e-42 144.8 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Foamy_virus_ENV PF03408.14 AAAP01003857.1_15 - 0.018 12.9 0.1 0.021 12.7 0.1 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein FA_hydroxylase PF04116.13 AAAP01003857.1_15 - 0.62 10.4 8.4 0.23 11.8 4.2 1.9 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily Hemerythrin PF01814.23 AAAP01003857.1_16 - 2.5e-11 44.3 0.5 3e-11 44.0 0.5 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HhH-GPD PF00730.25 AAAP01003857.1_17 - 5.5e-20 71.8 0.0 7.6e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAAP01003857.1_17 - 6.5e-08 32.1 0.0 1.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAAP01003857.1_17 - 0.0001 22.5 6.4 0.00019 21.6 6.4 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Inositol_P PF00459.25 AAAP01003857.1_18 - 1.1e-48 166.1 0.0 1.3e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RQC PF09382.10 AAAP01003857.1_19 - 4e-40 136.1 0.0 7.2e-40 135.3 0.0 1.4 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 AAAP01003857.1_19 - 9e-23 80.0 0.7 2.3e-22 78.8 0.2 2.0 2 0 0 2 2 2 1 HRDC domain RecQ_Zn_bind PF16124.5 AAAP01003857.1_19 - 7.4e-19 68.3 0.3 1.8e-18 67.0 0.3 1.7 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 AAAP01003857.1_19 - 8e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AAAP01003857.1_19 - 5.2e-16 59.0 0.0 8.8e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Zn-ribbon_8 PF09723.10 AAAP01003857.1_20 - 1.2e-12 47.7 2.5 1.6e-12 47.3 2.5 1.2 1 0 0 1 1 1 1 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 AAAP01003857.1_20 - 0.00034 20.5 0.4 0.00048 20.0 0.4 1.3 1 0 0 1 1 1 1 SprT-like zinc ribbon domain NOB1_Zn_bind PF08772.11 AAAP01003857.1_20 - 0.0013 18.8 0.1 0.0014 18.7 0.1 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 AAAP01003857.1_20 - 0.0049 16.9 0.3 0.0068 16.4 0.3 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 AAAP01003857.1_20 - 0.043 14.1 1.7 0.067 13.5 1.7 1.3 1 0 0 1 1 1 0 zinc-ribbon PhnA_Zn_Ribbon PF08274.12 AAAP01003857.1_20 - 0.049 13.6 0.2 0.092 12.7 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF1451 PF07295.11 AAAP01003857.1_20 - 0.049 13.7 0.9 0.076 13.0 0.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF35_N PF12172.8 AAAP01003857.1_20 - 1.2 9.1 8.1 2.9 7.8 0.3 2.5 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_4 PF13717.6 AAAP01003857.1_20 - 2 8.4 5.7 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain OSCP PF00213.18 AAAP01003857.1_21 - 1.9e-49 168.1 0.4 2.1e-49 168.0 0.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_ab PF00006.25 AAAP01003857.1_22 - 3e-74 249.3 0.0 4.6e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AAAP01003857.1_22 - 1.3e-48 164.5 2.2 2.3e-48 163.7 2.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AAAP01003857.1_22 - 1.5e-17 63.9 4.6 3.9e-17 62.5 4.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AAAP01003857.1_22 - 1.7e-05 24.9 0.8 5.3e-05 23.3 0.8 1.9 1 1 0 1 1 1 1 HAS barrel domain PanZ PF12568.8 AAAP01003857.1_22 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ CSD2 PF17876.1 AAAP01003857.1_22 - 0.15 12.3 1.0 1.1 9.5 0.2 2.3 2 0 0 2 2 2 0 Cold shock domain ATP-synt PF00231.19 AAAP01003857.1_23 - 2.9e-96 322.5 3.5 3.2e-96 322.3 3.5 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 AAAP01003857.1_24 - 6.7e-62 208.9 0.0 9.4e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AAAP01003857.1_24 - 1.5e-22 79.9 0.4 3.3e-22 78.8 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 AAAP01003857.1_24 - 0.00078 19.4 0.1 0.0019 18.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 AAAP01003857.1_24 - 0.0096 15.1 0.1 0.022 14.0 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain T3SS_ATPase_C PF18269.1 AAAP01003857.1_24 - 0.01 15.6 0.5 0.086 12.7 0.5 2.3 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 AAAP01003857.1_24 - 0.11 12.8 0.2 0.31 11.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003857.1_24 - 0.12 12.7 0.1 0.42 11.0 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 AAAP01003857.1_24 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAAP01003857.1_24 - 0.15 12.0 0.2 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 AAAP01003857.1_24 - 0.18 11.1 1.5 0.3 10.4 0.4 1.9 3 0 0 3 3 3 0 KaiC ATP-synt_DE_N PF02823.16 AAAP01003857.1_25 - 1.3e-25 89.1 0.3 1.7e-25 88.7 0.3 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain FA_desaturase_2 PF03405.14 AAAP01003857.1_26 - 1.6e-06 27.2 0.1 2.1e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 AAAP01003857.1_26 - 0.0011 19.4 0.0 0.0062 16.9 0.0 2.1 2 0 0 2 2 2 1 Rubrerythrin COQ7 PF03232.13 AAAP01003857.1_26 - 0.0055 16.5 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 NHR2 PF08788.11 AAAP01003857.1_26 - 0.25 11.1 1.4 1.2 9.0 1.4 2.4 1 1 0 1 1 1 0 NHR2 domain like ECH_1 PF00378.20 AAAP01003857.1_29 - 2.9e-49 167.6 0.0 3.4e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003857.1_29 - 2.3e-22 80.0 0.0 3.1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAD-oxidase_C PF02913.19 AAAP01003857.1_30 - 1.8e-56 191.5 0.1 3.1e-56 190.8 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAAP01003857.1_30 - 2.3e-24 85.7 0.1 4.1e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 AAAP01003857.1_30 - 9.4e-11 42.0 3.9 2.1e-10 40.9 3.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003857.1_30 - 2.8e-10 40.6 5.0 7.6e-10 39.2 5.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003857.1_30 - 2e-09 37.8 5.4 4.3e-09 36.8 5.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003857.1_30 - 1e-06 29.6 3.9 2.9e-06 28.1 3.9 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AAAP01003857.1_30 - 2.4e-06 27.6 5.4 6.9e-06 26.1 5.4 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003857.1_30 - 6.6e-06 25.7 13.9 0.0059 16.4 2.1 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003857.1_30 - 1.8e-05 24.7 9.9 0.0014 18.7 11.9 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003857.1_30 - 0.00025 21.0 13.1 0.066 13.3 2.7 3.2 2 0 0 2 2 2 2 4Fe-4S binding domain CCG PF02754.16 AAAP01003857.1_30 - 0.00026 21.2 11.7 0.00035 20.7 0.0 3.9 5 0 0 5 5 5 1 Cysteine-rich domain Fer4_18 PF13746.6 AAAP01003857.1_30 - 0.002 18.3 0.6 0.84 9.9 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003857.1_30 - 0.0054 16.8 11.3 0.079 13.1 11.3 2.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003857.1_30 - 0.048 14.2 17.7 0.086 13.4 1.7 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003857.1_30 - 0.069 13.3 16.3 0.56 10.4 2.3 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003857.1_30 - 3 9.0 17.6 11 7.3 4.1 3.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAAP01003857.1_30 - 5.7 7.9 11.0 7.2 7.5 1.3 2.7 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003857.1_30 - 6.7 7.3 15.7 2 9.0 2.6 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I LUD_dom PF02589.15 AAAP01003857.1_31 - 1.8e-30 106.1 0.0 1.1e-29 103.5 0.0 1.9 1 1 0 1 1 1 1 LUD domain LUD_dom PF02589.15 AAAP01003857.1_32 - 1.4e-53 181.4 0.1 2e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 LUD domain DUF3390 PF11870.8 AAAP01003857.1_32 - 7e-27 93.6 0.4 1.5e-26 92.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4_8 PF13183.6 AAAP01003857.1_32 - 6.4e-08 32.9 5.8 1.6e-07 31.7 5.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003857.1_32 - 2.2e-06 27.3 9.1 0.0011 18.7 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003857.1_32 - 1.8e-05 24.7 8.5 0.0037 17.3 10.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003857.1_32 - 9e-05 23.3 5.2 0.00022 22.1 5.2 1.7 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AAAP01003857.1_32 - 0.00012 22.2 4.8 0.019 15.1 0.1 2.6 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAAP01003857.1_32 - 0.00032 20.5 0.8 0.2 11.5 0.2 2.4 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_7 PF12838.7 AAAP01003857.1_32 - 0.00035 21.1 10.4 0.0012 19.4 10.4 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003857.1_32 - 0.00088 19.2 10.5 0.083 13.0 2.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003857.1_32 - 0.0013 19.3 5.9 0.0041 17.6 5.9 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AAAP01003857.1_32 - 0.0073 16.4 5.8 0.39 10.9 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003857.1_32 - 0.018 15.5 12.0 0.13 12.8 2.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003857.1_32 - 0.03 14.4 15.0 0.066 13.3 3.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AAAP01003857.1_32 - 0.043 14.0 3.5 5.1 7.3 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003857.1_32 - 0.053 14.5 13.5 0.3 12.1 1.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AAAP01003857.1_32 - 0.13 12.8 6.6 0.042 14.4 3.0 2.1 2 1 0 2 2 1 0 4Fe-4S single cluster domain of Ferredoxin I CCG PF02754.16 AAAP01003857.1_33 - 1.1e-15 57.6 0.4 2.8e-15 56.3 0.2 1.8 2 0 0 2 2 2 1 Cysteine-rich domain Rrf2 PF02082.20 AAAP01003858.1_1 - 1.6e-22 79.6 0.1 2.4e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01003858.1_1 - 0.00061 19.6 0.4 0.0095 15.8 0.1 2.3 2 0 0 2 2 2 1 MarR family HrcA_DNA-bdg PF03444.15 AAAP01003858.1_1 - 0.015 15.0 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_20 PF12840.7 AAAP01003858.1_1 - 0.034 14.2 0.1 0.16 12.0 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain PanZ PF12568.8 AAAP01003858.1_1 - 0.093 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ dUTPase PF00692.19 AAAP01003858.1_2 - 2.9e-31 107.8 0.0 3.3e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase DFP PF04127.15 AAAP01003858.1_3 - 2.3e-67 226.5 0.2 4.2e-67 225.6 0.0 1.5 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AAAP01003858.1_3 - 2.5e-45 154.0 0.2 4.8e-45 153.1 0.1 1.5 2 0 0 2 2 2 1 Flavoprotein Glyco_trans_4_4 PF13579.6 AAAP01003858.1_3 - 0.018 15.5 3.5 1.3 9.4 1.0 3.1 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain DUF3006 PF11213.8 AAAP01003858.1_3 - 0.12 12.6 0.9 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Cpn60_TCP1 PF00118.24 AAAP01003858.1_4 - 4.3e-99 332.4 17.8 6.6e-99 331.8 17.8 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn10 PF00166.21 AAAP01003858.1_5 - 8.4e-36 121.9 0.1 9.2e-36 121.8 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2076 PF09849.9 AAAP01003858.1_6 - 7.3e-50 170.4 5.5 8.4e-50 170.2 5.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1178 PF06676.11 AAAP01003858.1_7 - 9.6e-22 78.0 0.0 1.1e-21 77.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) Zn-ribbon_8 PF09723.10 AAAP01003858.1_7 - 0.0017 18.4 0.3 0.0017 18.4 0.3 2.6 2 2 0 2 2 2 1 Zinc ribbon domain Fer2_BFD PF04324.15 AAAP01003858.1_7 - 0.51 10.7 2.6 0.95 9.9 2.6 1.5 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Oxidored_q6 PF01058.22 AAAP01003858.1_8 - 3.2e-29 101.4 0.1 4.1e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_49kDa PF00346.19 AAAP01003858.1_9 - 4.9e-39 134.1 0.0 1.9e-32 112.4 0.0 2.2 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 AAAP01003858.1_9 - 2.6e-08 33.2 0.0 1.8e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Nickel-dependent hydrogenase Complex1_30kDa PF00329.19 AAAP01003858.1_9 - 0.01 16.5 0.1 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Proton_antipo_M PF00361.20 AAAP01003858.1_10 - 5.1e-52 176.9 23.5 1e-51 175.9 23.5 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAAP01003858.1_10 - 0.14 12.2 3.5 0.14 12.2 0.5 2.6 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF4818 PF16089.5 AAAP01003858.1_11 - 0.09 13.2 7.2 0.21 12.0 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4818) NADHdh PF00146.21 AAAP01003858.1_12 - 1.4e-18 67.3 14.8 1.5e-18 67.1 14.8 1.0 1 0 0 1 1 1 1 NADH dehydrogenase NADHdh PF00146.21 AAAP01003858.1_13 - 0.0067 15.8 0.0 0.0086 15.4 0.0 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Proton_antipo_M PF00361.20 AAAP01003858.1_15 - 1.2e-50 172.4 19.4 1.2e-50 172.4 19.4 2.3 1 1 1 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AAAP01003858.1_15 - 0.00022 21.2 0.0 0.00022 21.2 0.0 2.9 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF962 PF06127.11 AAAP01003858.1_15 - 0.0043 17.1 0.0 0.73 10.0 0.0 3.6 2 1 0 2 2 2 1 Protein of unknown function (DUF962) DUF1378 PF07125.11 AAAP01003858.1_15 - 0.095 12.9 0.6 0.61 10.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Glucosaminidase PF01832.20 AAAP01003858.1_16 - 1.9e-09 37.9 0.0 4.4e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase GARS_A PF01071.19 AAAP01003858.1_18 - 4.9e-78 261.4 0.8 1.1e-77 260.2 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AAAP01003858.1_18 - 1.8e-35 121.6 1.6 3.9e-35 120.5 0.1 2.3 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AAAP01003858.1_18 - 3.8e-27 94.4 1.0 3.8e-27 94.4 1.0 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 AAAP01003858.1_18 - 7.9e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AAAP01003858.1_18 - 0.00046 19.8 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AAAP01003858.1_18 - 0.00055 19.5 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 AAAP01003858.1_18 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 AAAP01003858.1_18 - 0.031 13.8 0.0 0.087 12.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain LAL_C2 PF18603.1 AAAP01003858.1_18 - 1.7 8.9 6.2 2.8 8.2 3.8 2.5 2 1 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 tRNA_anti_2 PF13742.6 AAAP01003858.1_19 - 1.5e-28 98.9 0.0 2.1e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Exonuc_VII_L PF02601.15 AAAP01003858.1_19 - 4.2e-26 92.2 0.1 5.7e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti-codon PF01336.25 AAAP01003858.1_19 - 3.6e-09 36.5 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RecJ_OB PF17768.1 AAAP01003858.1_19 - 0.0025 18.0 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 RecJ OB domain UPF0126 PF03458.13 AAAP01003858.1_19 - 0.085 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 UPF0126 domain Exonuc_VII_L PF02601.15 AAAP01003858.1_20 - 5.5e-55 187.1 3.7 1.3e-53 182.6 3.7 2.0 1 1 0 1 1 1 1 Exonuclease VII, large subunit Spc7 PF08317.11 AAAP01003858.1_20 - 0.0019 17.1 1.0 0.0025 16.7 1.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1704 PF08014.11 AAAP01003858.1_20 - 0.014 14.4 0.7 0.019 14.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) PRKG1_interact PF15898.5 AAAP01003858.1_20 - 0.06 14.3 2.1 0.14 13.1 2.1 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CorA PF01544.18 AAAP01003858.1_20 - 0.11 11.8 2.9 0.16 11.3 2.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ERM PF00769.19 AAAP01003858.1_20 - 0.21 11.4 8.9 0.36 10.6 8.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tcell_CD4_C PF12104.8 AAAP01003858.1_20 - 2.1 8.3 4.3 21 5.2 1.0 3.1 2 1 0 2 2 2 0 T cell CD4 receptor C terminal region SRP54 PF00448.22 AAAP01003858.1_21 - 7.5e-70 234.6 1.0 1e-69 234.1 1.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AAAP01003858.1_21 - 3.3e-10 40.0 1.1 7.8e-10 38.8 1.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 AAAP01003858.1_21 - 5.5e-08 32.8 0.7 1.2e-07 31.6 0.7 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AAAP01003858.1_21 - 2.1e-05 24.2 2.0 5.1e-05 22.9 2.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AAAP01003858.1_21 - 2.6e-05 24.5 0.1 6.5e-05 23.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 AAAP01003858.1_21 - 5.2e-05 23.7 0.5 0.00011 22.7 0.2 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 AAAP01003858.1_21 - 7.5e-05 23.2 0.2 0.00021 21.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AAAP01003858.1_21 - 0.00013 21.3 0.1 0.00024 20.5 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 AAAP01003858.1_21 - 0.0025 18.2 0.1 0.0041 17.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 AAAP01003858.1_21 - 0.0033 17.2 0.8 0.12 12.1 0.8 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 AAAP01003858.1_21 - 0.0058 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AAAP01003858.1_21 - 0.0064 16.7 1.3 0.017 15.3 0.6 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01003858.1_21 - 0.0069 16.8 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AAAP01003858.1_21 - 0.0092 16.0 0.0 0.029 14.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 AAAP01003858.1_21 - 0.02 15.4 0.1 0.047 14.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 AAAP01003858.1_21 - 0.024 13.6 1.0 0.055 12.4 0.9 1.8 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 AAAP01003858.1_21 - 0.038 13.9 1.0 0.39 10.6 0.4 2.2 2 0 0 2 2 2 0 NTPase MobB PF03205.14 AAAP01003858.1_21 - 0.053 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 AAAP01003858.1_21 - 0.059 13.3 0.9 0.34 10.8 0.3 2.1 2 0 0 2 2 2 0 NACHT domain DnaB_bind PF10410.9 AAAP01003858.1_21 - 0.062 13.5 0.6 10 6.4 0.1 3.1 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Thymidylate_kin PF02223.17 AAAP01003858.1_21 - 0.064 12.9 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.6 AAAP01003858.1_21 - 0.073 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEK_C PF08766.11 AAAP01003858.1_21 - 0.083 12.8 1.9 0.16 11.9 1.5 1.8 2 0 0 2 2 1 0 DEK C terminal domain AAA_28 PF13521.6 AAAP01003858.1_21 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AAAP01003858.1_21 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit TniQ PF06527.11 AAAP01003858.1_21 - 0.14 12.9 0.0 0.38 11.5 0.0 1.7 2 0 0 2 2 2 0 TniQ AAA_14 PF13173.6 AAAP01003858.1_21 - 0.14 12.2 0.1 0.3 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003858.1_21 - 0.18 11.5 0.4 0.48 10.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AAAP01003858.1_21 - 0.2 11.1 0.1 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Radical_SAM PF04055.21 AAAP01003858.1_22 - 1.1e-23 84.5 0.0 1.4e-22 80.9 0.0 2.5 2 1 1 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 AAAP01003858.1_22 - 1.7e-17 63.2 0.3 9.2e-17 60.9 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 B12-binding PF02310.19 AAAP01003858.1_22 - 0.0014 18.7 0.3 0.027 14.5 0.1 2.5 2 0 0 2 2 2 1 B12 binding domain TRAM_2 PF18693.1 AAAP01003858.1_22 - 0.02 15.1 0.4 0.52 10.5 0.1 3.2 2 1 0 2 2 2 0 TRAM domain Lipase_GDSL_2 PF13472.6 AAAP01003858.1_22 - 0.023 15.1 0.2 1.6 9.1 0.1 2.9 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DAP_epimerase PF01678.19 AAAP01003858.1_23 - 1.1e-53 180.5 0.2 8.1e-26 90.6 0.1 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AAAP01003858.1_23 - 0.012 15.0 0.0 0.031 13.7 0.0 1.6 1 1 0 1 1 1 0 Phenazine biosynthesis-like protein DHODB_Fe-S_bind PF10418.9 AAAP01003858.1_23 - 0.16 11.8 1.5 0.35 10.7 1.5 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Na_H_Exchanger PF00999.21 AAAP01003858.1_24 - 2.6e-46 158.2 44.2 3.2e-46 157.8 44.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorC_HlyC PF03471.17 AAAP01003858.1_24 - 3.9e-06 26.8 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Transporter associated domain YlaH PF14036.6 AAAP01003858.1_24 - 0.2 12.0 2.8 4.3 7.7 0.1 3.4 3 0 0 3 3 3 0 YlaH-like protein Rhodanese PF00581.20 AAAP01003858.1_25 - 5.3e-14 52.6 0.0 6.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Nitroreductase PF00881.24 AAAP01003858.1_26 - 4.1e-15 56.2 0.1 3e-06 27.4 0.0 3.1 2 1 0 2 2 2 2 Nitroreductase family DAGK_cat PF00781.24 AAAP01003858.1_28 - 3.4e-28 97.8 0.3 5.4e-28 97.1 0.3 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AAAP01003858.1_28 - 0.0098 15.1 0.2 0.014 14.6 0.2 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Fe-ADH_2 PF13685.6 AAAP01003858.1_28 - 0.079 12.7 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Metallophos_2 PF12850.7 AAAP01003858.1_29 - 1.3e-11 45.0 2.0 1.5e-10 41.5 2.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AAAP01003858.1_29 - 4.8e-11 43.6 3.5 8.5e-11 42.7 3.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_trans_1_4 PF13692.6 AAAP01003858.1_30 - 2.9e-19 69.8 0.0 5.6e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003858.1_30 - 7.8e-16 58.1 0.0 2.7e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003858.1_30 - 5.1e-13 49.4 0.1 2.1e-12 47.4 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01003858.1_30 - 0.00046 20.7 0.3 0.00046 20.7 0.3 2.4 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAAP01003858.1_30 - 0.035 14.5 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 MCPsignal PF00015.21 AAAP01003858.1_32 - 6.4e-30 104.2 49.7 7.9e-30 103.9 24.9 3.3 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003858.1_32 - 1.8e-08 34.6 0.0 1.8e-08 34.6 0.0 3.6 4 0 0 4 4 4 1 HAMP domain 4HB_MCP_1 PF12729.7 AAAP01003858.1_32 - 4e-05 23.2 0.0 4e-05 23.2 0.0 3.7 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction DUF1664 PF07889.12 AAAP01003858.1_32 - 0.00022 21.2 12.1 0.018 15.1 2.3 4.1 3 1 0 3 3 3 2 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003858.1_32 - 0.00034 20.8 19.5 0.053 13.8 1.3 4.8 2 2 3 5 5 5 4 Bacterial protein of unknown function (DUF948) DegQ PF08181.11 AAAP01003858.1_32 - 0.065 13.3 0.9 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 DegQ (SacQ) family ChaC PF04752.12 AAAP01003858.1_32 - 0.26 11.3 2.5 0.4 10.7 0.1 2.4 2 1 1 3 3 3 0 ChaC-like protein DUF3450 PF11932.8 AAAP01003858.1_32 - 0.66 9.2 27.5 0.23 10.7 1.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 AAAP01003858.1_32 - 0.78 8.9 3.9 2.2 7.5 1.6 2.3 2 0 0 2 2 2 0 TMPIT-like protein Laminin_I PF06008.14 AAAP01003858.1_32 - 2.3 7.8 22.8 1.5 8.5 10.8 3.3 1 1 3 4 4 4 0 Laminin Domain I FlaC_arch PF05377.11 AAAP01003858.1_32 - 2.9 8.3 7.9 4.5 7.8 0.0 4.3 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 AAAP01003858.1_32 - 4.6 7.3 22.6 0.62 10.1 8.5 3.7 2 1 0 3 3 3 0 Laminin Domain II Lin-8 PF03353.15 AAAP01003858.1_32 - 5.8 6.4 7.3 11 5.4 7.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GAS PF13851.6 AAAP01003858.1_32 - 6.8 6.0 9.9 0.53 9.6 3.5 2.4 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding PMT_2 PF13231.6 AAAP01003858.1_33 - 3.9e-09 36.9 13.8 3.9e-09 36.9 13.8 3.8 2 1 2 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 AAAP01003858.1_33 - 1.2e-07 31.6 7.2 1.2e-07 31.6 7.2 2.7 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PAP2 PF01569.21 AAAP01003858.1_34 - 2.3e-23 82.5 6.9 2.3e-23 82.5 6.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AAAP01003858.1_34 - 3.1e-06 27.0 8.3 3.1e-06 27.0 8.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily WzyE PF06899.11 AAAP01003858.1_34 - 0.0042 16.1 2.7 0.047 12.6 0.1 2.2 1 1 1 2 2 2 2 WzyE protein, O-antigen assembly polymerase MFS_1 PF07690.16 AAAP01003858.1_35 - 3.9e-47 160.9 80.0 3.2e-41 141.5 52.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01003858.1_35 - 5.7e-25 88.1 8.1 5.7e-25 88.1 8.1 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 AAAP01003858.1_35 - 1.7e-08 34.1 14.7 1.7e-08 34.1 14.7 2.3 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAAP01003858.1_35 - 0.00011 21.2 10.8 0.045 12.6 4.1 2.3 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 AAAP01003858.1_35 - 8.9 4.5 9.2 52 1.9 6.3 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 AAAP01003858.1_36 - 8.6e-87 291.6 0.0 9.8e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003858.1_36 - 0.00024 21.3 0.9 0.00052 20.2 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAAP01003858.1_36 - 0.0038 16.5 1.0 0.0055 16.0 1.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 AAAP01003858.1_36 - 0.0065 15.8 1.6 0.011 15.0 1.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AAAP01003858.1_36 - 0.05 12.8 1.8 0.052 12.8 0.7 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003858.1_36 - 0.097 11.4 0.8 0.14 10.8 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 AAAP01003858.1_36 - 0.19 10.7 0.7 0.35 9.9 0.7 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein LigB PF02900.18 AAAP01003858.1_37 - 1e-58 198.6 0.0 1.2e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LigA PF07746.11 AAAP01003858.1_38 - 7e-34 115.8 0.3 8.2e-34 115.6 0.3 1.1 1 0 0 1 1 1 1 Aromatic-ring-opening dioxygenase LigAB, LigA subunit FAP206 PF12018.8 AAAP01003858.1_38 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function S4 PF01479.25 AAAP01003859.1_1 - 5.4e-12 45.2 0.0 6.1e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AAAP01003859.1_1 - 0.00022 21.0 0.0 0.00023 20.9 0.0 1.0 1 0 0 1 1 1 1 S4 domain Ribonuc_red_lgC PF02867.15 AAAP01003859.1_2 - 1e-138 463.2 0.0 2.8e-138 461.7 0.0 1.7 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AAAP01003859.1_2 - 6.2e-09 35.7 0.0 1.8e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain IBR PF01485.21 AAAP01003859.1_2 - 0.12 12.6 3.6 0.27 11.5 3.6 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Acyltransferase PF01553.21 AAAP01003859.1_3 - 4.4e-20 71.7 0.0 6.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase FtsX PF02687.21 AAAP01003859.1_5 - 0.0006 20.2 3.1 0.0006 20.2 3.1 2.8 2 1 0 2 2 2 1 FtsX-like permease family Adeno_PX PF05829.12 AAAP01003859.1_5 - 3.8 7.5 6.5 0.61 10.0 1.7 2.2 2 1 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) DUF2207 PF09972.9 AAAP01003859.1_5 - 4 6.1 4.7 7.2 5.3 0.8 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ABC_tran PF00005.27 AAAP01003859.1_6 - 5.1e-33 114.5 0.0 6.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003859.1_6 - 6.4e-08 32.8 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003859.1_6 - 0.00083 18.8 0.0 0.0035 16.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003859.1_6 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003859.1_6 - 0.0034 17.8 0.0 0.0047 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AAAP01003859.1_6 - 0.0081 15.8 0.2 0.022 14.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003859.1_6 - 0.012 15.6 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AAAP01003859.1_6 - 0.046 14.3 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAAP01003859.1_6 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 AAAP01003859.1_6 - 0.071 12.0 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 AAAP01003859.1_6 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_27 PF13514.6 AAAP01003859.1_6 - 0.092 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AAAP01003859.1_6 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 AAAP01003859.1_6 - 0.16 12.5 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003859.1_6 - 0.17 11.6 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 AAAP01003859.1_6 - 0.21 10.7 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF4393 PF14337.6 AAAP01003859.1_7 - 0.00035 20.4 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4393) DnaJ_C PF01556.18 AAAP01003859.1_8 - 1.3e-40 138.9 0.0 1.7e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AAAP01003859.1_8 - 7.9e-28 96.4 2.3 7.9e-28 96.4 2.3 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AAAP01003859.1_8 - 2.4e-13 50.2 17.6 4.5e-13 49.4 17.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AAAP01003859.1_8 - 0.00083 19.3 18.1 0.025 14.6 5.8 2.9 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein UvsW PF11637.8 AAAP01003859.1_8 - 0.0074 16.4 0.1 0.055 13.6 0.0 2.4 2 0 0 2 2 2 1 ATP-dependant DNA helicase UvsW LTXXQ PF07813.12 AAAP01003859.1_8 - 0.028 15.1 0.5 10 6.9 0.0 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein DUF1356 PF07092.12 AAAP01003859.1_8 - 0.91 8.8 10.2 2.8 7.1 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) TackOD1 PF18551.1 AAAP01003859.1_8 - 1.1 8.9 4.3 1.5 8.5 0.4 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 AAAP01003859.1_8 - 2.5 8.1 8.3 1.3e+02 2.6 8.3 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RseC_MucC PF04246.12 AAAP01003859.1_8 - 5.5 6.9 4.9 76 3.3 4.9 2.3 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC HSP70 PF00012.20 AAAP01003859.1_9 - 6.5e-276 916.3 11.8 7.4e-276 916.1 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AAAP01003859.1_9 - 1.7e-18 66.6 2.2 1.8e-16 59.9 0.8 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 AAAP01003859.1_9 - 0.00048 20.5 4.3 0.15 12.5 0.0 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DMRL_synthase PF00885.19 AAAP01003859.1_9 - 0.016 15.1 0.2 0.053 13.3 0.2 1.8 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase MrpF_PhaF PF04066.13 AAAP01003859.1_10 - 0.0048 17.3 0.2 0.0062 16.9 0.2 1.2 1 0 0 1 1 1 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) CobN-Mg_chel PF02514.16 AAAP01003859.1_11 - 0 1243.8 0.0 0 1243.6 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase cobW PF02492.19 AAAP01003859.1_13 - 4.2e-57 192.6 0.0 5.5e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AAAP01003859.1_13 - 1.6e-14 53.5 0.0 3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_28 PF13521.6 AAAP01003859.1_13 - 0.0045 17.2 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003859.1_13 - 0.011 16.1 0.3 0.036 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01003859.1_13 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AAAP01003859.1_13 - 0.016 15.2 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AAAP01003859.1_13 - 0.029 14.5 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAAP01003859.1_13 - 0.047 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arf PF00025.21 AAAP01003859.1_13 - 0.052 13.0 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.14 AAAP01003859.1_13 - 0.055 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 AAAP01003859.1_13 - 0.068 13.1 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 AAAP01003859.1_13 - 0.069 13.7 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAAP01003859.1_13 - 0.078 11.9 0.3 0.72 8.8 0.1 2.3 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 AAAP01003859.1_13 - 0.17 11.4 0.4 3.2 7.2 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 AAAP01003859.1_13 - 0.23 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CobU PF02283.16 AAAP01003859.1_14 - 7.3e-60 201.4 0.0 8.2e-60 201.2 0.0 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase RHH_1 PF01402.21 AAAP01003859.1_14 - 0.2 11.7 1.1 0.34 10.9 0.0 2.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Cytochrom_C PF00034.21 AAAP01003859.1_15 - 3.2e-18 66.7 0.5 1.7e-07 32.3 0.2 2.7 2 2 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003859.1_15 - 2e-15 56.8 0.1 1.3e-06 28.6 0.1 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DHOR PF06537.11 AAAP01003859.1_15 - 0.0023 16.6 0.3 0.56 8.8 0.0 2.2 1 1 0 2 2 2 2 Di-haem oxidoreductase, putative peroxidase Cytochrome_C7 PF14522.6 AAAP01003859.1_15 - 0.0047 16.9 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003859.1_15 - 0.0054 16.5 0.3 0.93 9.3 0.1 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) FixO PF02433.15 AAAP01003859.1_15 - 0.07 12.6 0.1 8.8 5.7 0.0 2.5 2 1 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO PSCyt1 PF07635.11 AAAP01003859.1_15 - 0.13 12.9 1.0 25 5.5 0.1 2.7 2 0 0 2 2 2 0 Planctomycete cytochrome C DUF3365 PF11845.8 AAAP01003859.1_15 - 0.41 11.0 5.3 8.9 6.6 0.2 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3365) HemY_N PF07219.13 AAAP01003859.1_16 - 1.7e-26 92.5 6.7 1.7e-26 92.5 6.7 5.6 3 1 1 5 5 5 2 HemY protein N-terminus TPR_19 PF14559.6 AAAP01003859.1_16 - 2.3e-09 37.6 21.4 0.0013 19.2 0.4 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003859.1_16 - 0.0082 16.8 4.3 0.0082 16.8 4.3 5.4 3 1 1 5 5 5 2 Tetratricopeptide repeat Cyt_bd_oxida_II PF02322.15 AAAP01003859.1_16 - 0.2 11.0 5.5 0.32 10.3 5.5 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Sec6 PF06046.13 AAAP01003859.1_16 - 0.28 9.5 0.0 0.4 9.0 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 TPR_2 PF07719.17 AAAP01003859.1_16 - 0.73 10.1 0.1 0.73 10.1 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Anti-TRAP PF15777.5 AAAP01003859.1_16 - 1.1 9.2 3.8 2.3 8.3 3.8 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Mitofilin PF09731.9 AAAP01003859.1_17 - 5.6e-15 55.2 15.8 7.6e-15 54.8 15.8 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Seryl_tRNA_N PF02403.22 AAAP01003859.1_17 - 0.0025 18.0 6.1 0.047 13.9 0.6 2.6 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Wbp11 PF09429.10 AAAP01003859.1_17 - 0.0076 16.6 4.1 2.1 8.8 0.1 3.0 3 0 0 3 3 3 2 WW domain binding protein 11 DUF3584 PF12128.8 AAAP01003859.1_17 - 0.062 10.8 2.5 0.095 10.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 AAAP01003859.1_17 - 0.062 13.1 0.8 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 AAAP01003859.1_17 - 0.063 12.1 3.2 0.1 11.4 3.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc29 PF17082.5 AAAP01003859.1_17 - 0.064 13.1 0.1 0.092 12.6 0.1 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4366 PF14283.6 AAAP01003859.1_17 - 0.13 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zw10 PF06248.13 AAAP01003859.1_17 - 0.21 10.1 0.2 0.28 9.7 0.2 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Phage_GP20 PF06810.11 AAAP01003859.1_17 - 0.23 11.2 0.9 2.6 7.9 0.1 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 AAAP01003859.1_17 - 0.27 11.7 1.0 18 5.8 0.5 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GAS PF13851.6 AAAP01003859.1_17 - 0.31 10.4 4.1 1.1 8.6 0.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 AAAP01003859.1_17 - 0.32 11.2 5.1 0.57 10.4 3.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 AAAP01003859.1_17 - 0.64 10.4 5.4 19 5.7 0.2 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain Atg14 PF10186.9 AAAP01003859.1_17 - 0.71 8.9 5.0 0.25 10.4 2.5 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 AAAP01003859.1_17 - 1.5 9.5 6.6 55 4.5 0.0 3.7 1 1 1 2 2 2 0 SlyX ABC_tran_CTD PF16326.5 AAAP01003859.1_17 - 2.4 8.5 11.9 17 5.8 4.2 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain ZapB PF06005.12 AAAP01003859.1_17 - 4.9 7.7 11.0 19 5.8 6.5 2.8 1 1 0 2 2 2 0 Cell division protein ZapB Trimer_CC PF08954.11 AAAP01003859.1_17 - 6 6.5 9.8 9 6.0 0.1 2.9 3 0 0 3 3 3 0 Trimerisation motif HEM4 PF02602.15 AAAP01003859.1_18 - 5.5e-29 101.2 3.6 6.3e-29 101.0 3.6 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Porphobil_deam PF01379.20 AAAP01003859.1_19 - 1.4e-79 266.4 0.1 1.7e-79 266.1 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AAAP01003859.1_19 - 1.4e-18 67.0 0.0 2.5e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Peptidase_M22 PF00814.25 AAAP01003859.1_20 - 1e-90 304.2 0.1 1.1e-90 304.0 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF1487 PF07368.11 AAAP01003859.1_20 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) FGGY_C PF02782.16 AAAP01003859.1_20 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain GreA_GreB PF01272.19 AAAP01003859.1_21 - 2.3e-25 88.3 0.1 4.4e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 AAAP01003859.1_21 - 2.5e-23 82.0 0.0 4.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal Hemerythrin PF01814.23 AAAP01003859.1_22 - 1.9e-10 41.5 0.0 2.1e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MutL_C PF08676.11 AAAP01003859.1_23 - 1.2e-49 167.8 0.0 1.9e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 AAAP01003859.1_23 - 6.1e-35 119.5 0.0 8.7e-35 119.0 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AAAP01003859.1_23 - 1.6e-10 40.9 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01003859.1_23 - 1.4e-05 25.5 0.0 3.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GGDEF PF00990.21 AAAP01003859.1_24 - 2.1e-45 154.3 0.1 4.1e-45 153.4 0.1 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AAAP01003859.1_24 - 1.4e-25 89.7 0.3 1.8e-13 50.7 0.1 3.4 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01003859.1_24 - 1.1e-15 57.7 0.0 2.4e-05 24.5 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AAAP01003859.1_24 - 4.3e-12 46.0 0.1 8.4e-07 29.0 0.0 3.6 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 AAAP01003859.1_24 - 6e-07 29.3 0.4 0.16 12.1 0.0 3.5 3 0 0 3 3 3 2 PAS domain PGI PF00342.19 AAAP01003859.1_25 - 2.5e-234 778.3 0.0 2.8e-234 778.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF3387 PF11867.8 AAAP01003859.1_25 - 0.0082 15.6 0.2 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3387) Fer4_5 PF12801.7 AAAP01003859.1_26 - 7.9e-10 38.5 17.9 4.4e-08 32.9 9.6 4.2 4 0 0 4 4 4 2 4Fe-4S binding domain OprB PF04966.12 AAAP01003859.1_27 - 1.9e-20 73.6 7.5 1.4e-19 70.8 7.5 2.3 1 1 0 1 1 1 1 Carbohydrate-selective porin, OprB family DUF4164 PF13747.6 AAAP01003859.1_27 - 0.97 9.8 5.3 2 8.8 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ABC_tran_CTD PF16326.5 AAAP01003859.1_27 - 1.4 9.2 9.0 6.3 7.1 9.0 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain Rrf2 PF02082.20 AAAP01003860.1_1 - 3.3e-23 81.8 0.2 5.3e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Transcriptional regulator DUF3124 PF11322.8 AAAP01003860.1_3 - 1.6e-45 154.3 0.0 1.8e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3124) DUF4164 PF13747.6 AAAP01003860.1_4 - 2.2e-08 34.3 4.4 0.00026 21.2 0.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) ZapA PF05164.13 AAAP01003860.1_5 - 1.7e-20 73.3 0.1 2e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Cell division protein ZapA 5-FTHF_cyc-lig PF01812.20 AAAP01003860.1_6 - 9.1e-29 100.6 0.0 1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family YmdB PF13277.6 AAAP01003860.1_7 - 1.1e-95 319.8 0.0 1.2e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 YmdB-like protein Metallophos PF00149.28 AAAP01003860.1_7 - 0.0028 18.2 0.1 0.0093 16.5 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 AAAP01003860.1_7 - 0.012 15.1 0.1 0.56 9.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap MlaC PF05494.12 AAAP01003860.1_8 - 1.3e-29 103.1 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 MlaC protein Transcrip_reg PF01709.20 AAAP01003860.1_9 - 8.3e-90 300.4 0.0 9.4e-90 300.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator RuvC PF02075.17 AAAP01003860.1_10 - 5.9e-45 152.8 0.1 6.8e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC RuvA_C PF07499.13 AAAP01003860.1_11 - 2.4e-13 50.3 0.4 5.9e-13 49.0 0.4 1.7 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH_5 PF14520.6 AAAP01003860.1_11 - 5.7e-12 46.1 1.4 9.6e-12 45.3 0.6 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_N PF01330.21 AAAP01003860.1_11 - 0.00016 21.7 0.0 0.001 19.1 0.0 2.2 2 1 0 2 2 2 1 RuvA N terminal domain Transposase_20 PF02371.16 AAAP01003860.1_11 - 0.095 13.0 0.2 20 5.6 0.0 2.5 2 1 0 2 2 2 0 Transposase IS116/IS110/IS902 family HHH PF00633.23 AAAP01003860.1_11 - 0.097 12.6 4.7 5.6 7.0 0.3 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif RuvB_N PF05496.12 AAAP01003860.1_12 - 1.1e-79 265.7 0.0 1.6e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AAAP01003860.1_12 - 3.4e-30 103.6 0.4 7.3e-30 102.5 0.4 1.6 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AAAP01003860.1_12 - 1.4e-27 95.4 0.0 2.3e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AAAP01003860.1_12 - 9.3e-19 68.2 0.0 1.6e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003860.1_12 - 3.5e-07 30.3 0.3 0.00014 21.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003860.1_12 - 4e-05 24.1 0.5 0.00097 19.6 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AAAP01003860.1_12 - 0.00011 21.7 0.1 0.042 13.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAAP01003860.1_12 - 0.00014 21.7 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 AAAP01003860.1_12 - 0.00021 20.6 0.2 0.0024 17.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 AAAP01003860.1_12 - 0.00024 21.4 0.5 0.067 13.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 AAAP01003860.1_12 - 0.00027 21.1 0.0 0.00074 19.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AAAP01003860.1_12 - 0.0011 18.7 0.0 0.89 9.2 0.0 2.2 1 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 AAAP01003860.1_12 - 0.0031 17.5 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 AAAP01003860.1_12 - 0.0042 17.1 0.0 2.3 8.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 AAAP01003860.1_12 - 0.0049 16.1 0.0 0.044 13.0 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 AAAP01003860.1_12 - 0.0084 16.0 0.2 0.17 11.8 0.0 2.2 1 1 1 2 2 2 1 NTPase Rad17 PF03215.15 AAAP01003860.1_12 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 AAAP01003860.1_12 - 0.014 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AAAP01003860.1_12 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 AAAP01003860.1_12 - 0.022 14.8 0.0 0.062 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AAAP01003860.1_12 - 0.025 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.18 AAAP01003860.1_12 - 0.055 13.3 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein Cytidylate_kin PF02224.18 AAAP01003860.1_12 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 AAAP01003860.1_12 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AAAP01003860.1_12 - 0.13 12.0 0.2 0.92 9.2 0.2 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 AAAP01003860.1_12 - 0.17 12.0 0.0 2.4 8.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) MCM PF00493.23 AAAP01003860.1_12 - 0.2 10.7 0.0 4.5 6.3 0.0 2.1 1 1 0 1 1 1 0 MCM P-loop domain GAIN_A PF18619.1 AAAP01003860.1_13 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A 4HBT PF03061.22 AAAP01003860.1_14 - 2.6e-18 66.2 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAAP01003860.1_14 - 2e-13 50.9 0.0 2.4e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AAAP01003860.1_14 - 0.00034 20.0 0.0 0.00035 20.0 0.0 1.0 1 0 0 1 1 1 1 Acyl-ACP thioesterase MotA_ExbB PF01618.16 AAAP01003860.1_15 - 2.9e-39 133.7 0.1 4.3e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF5305 PF17231.2 AAAP01003860.1_15 - 0.19 11.1 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Rhomboid PF01694.22 AAAP01003860.1_15 - 1.3 9.1 5.8 1.7 8.6 0.3 2.1 2 0 0 2 2 2 0 Rhomboid family ExbD PF02472.16 AAAP01003860.1_16 - 5.9e-32 110.6 0.1 7.3e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 AAAP01003860.1_17 - 2.8e-05 24.3 0.2 2.8e-05 24.3 0.2 3.8 4 2 0 4 4 4 1 TonB C terminal TolB_N PF04052.13 AAAP01003860.1_18 - 1.3e-36 124.9 0.0 2.1e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 TolB amino-terminal domain PD40 PF07676.12 AAAP01003860.1_18 - 1.2e-28 98.4 10.0 6.1e-11 42.0 0.0 6.2 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Pectate_lyase22 PF14583.6 AAAP01003860.1_18 - 3.4e-06 26.0 0.0 0.42 9.2 0.0 3.2 1 1 2 3 3 3 3 Oligogalacturonate lyase DUF5050 PF16472.5 AAAP01003860.1_18 - 3.9e-05 23.0 0.0 0.0017 17.7 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5050) DPPIV_N PF00930.21 AAAP01003860.1_18 - 0.0004 19.3 0.0 0.32 9.7 0.0 3.5 2 1 2 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 AAAP01003860.1_18 - 0.0039 17.0 0.2 0.035 13.9 0.0 2.6 3 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain OmpA PF00691.20 AAAP01003860.1_19 - 2.1e-24 85.7 0.2 3.1e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 OmpA family RXLR PF16810.5 AAAP01003860.1_19 - 0.046 14.2 0.0 0.087 13.3 0.0 1.5 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity TAT_signal PF10518.9 AAAP01003860.1_19 - 6.1 6.9 10.2 2.3 8.2 1.5 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence TPR_6 PF13174.6 AAAP01003860.1_23 - 8.6e-09 35.5 1.4 0.018 15.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003860.1_23 - 3e-07 31.0 0.1 6.4e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat YfiO PF13525.6 AAAP01003860.1_23 - 0.0049 16.6 0.1 0.027 14.2 0.1 1.7 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_2 PF07719.17 AAAP01003860.1_23 - 0.011 15.8 0.9 0.6 10.4 0.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003860.1_23 - 0.021 15.6 0.1 6.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP_bind_3 PF01171.20 AAAP01003860.1_24 - 5.8e-52 176.1 0.0 7.9e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Peptidase_M41 PF01434.18 AAAP01003860.1_25 - 2.1e-68 230.0 0.1 3.1e-68 229.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AAAP01003860.1_25 - 2.1e-46 157.6 0.0 1.2e-45 155.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AAAP01003860.1_25 - 2.7e-12 46.3 0.3 5.5e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 AAAP01003860.1_25 - 9.5e-10 38.8 0.0 3.2e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 AAAP01003860.1_25 - 5.3e-07 29.7 0.1 8.5e-06 25.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AAAP01003860.1_25 - 5.7e-05 22.5 0.0 0.00016 21.0 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 AAAP01003860.1_25 - 8.4e-05 23.0 0.2 0.00036 21.0 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 AAAP01003860.1_25 - 0.00047 19.9 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAAP01003860.1_25 - 0.00084 19.6 0.1 0.028 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AAAP01003860.1_25 - 0.0039 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 AAAP01003860.1_25 - 0.0058 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 AAAP01003860.1_25 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AAAP01003860.1_25 - 0.028 13.8 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AAAP01003860.1_25 - 0.092 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 AAAP01003860.1_25 - 0.12 12.8 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AAAP01003860.1_25 - 0.13 12.8 0.0 0.51 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 AAAP01003860.1_25 - 0.16 11.8 0.2 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 AAAP01003860.1_25 - 0.17 11.2 0.2 0.73 9.1 0.1 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_7 PF12775.7 AAAP01003860.1_25 - 0.18 11.3 0.1 0.54 9.7 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 AAAP01003860.1_25 - 0.2 12.2 0.1 0.52 10.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter Pterin_bind PF00809.22 AAAP01003860.1_26 - 2.7e-77 259.7 0.0 4.1e-77 259.1 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme DUF4405 PF14358.6 AAAP01003860.1_27 - 2.9e-07 30.9 4.5 5.8e-07 30.0 4.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) Ferric_reduct PF01794.19 AAAP01003860.1_27 - 0.00097 19.3 3.3 0.002 18.2 3.3 1.5 1 1 0 1 1 1 1 Ferric reductase like transmembrane component PepSY_TM_like_2 PF16357.5 AAAP01003860.1_27 - 0.072 13.1 1.0 0.15 12.1 1.0 1.4 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF202 PF02656.15 AAAP01003860.1_27 - 0.23 11.9 5.6 0.29 11.6 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PGM_PMM_I PF02878.16 AAAP01003860.1_28 - 6.6e-43 145.7 0.0 1.4e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AAAP01003860.1_28 - 4.3e-34 117.1 0.0 7.9e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AAAP01003860.1_28 - 3.4e-17 62.9 0.0 7.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AAAP01003860.1_28 - 1.1e-12 48.0 1.1 3.5e-12 46.3 0.9 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4253 PF14062.6 AAAP01003860.1_29 - 0.0056 16.8 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4253) TPR_14 PF13428.6 AAAP01003860.1_29 - 0.042 14.7 0.2 0.16 12.9 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Cas3_C PF18395.1 AAAP01003860.1_29 - 0.14 12.7 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Cas3 C-terminal domain Phos_pyr_kin PF08543.12 AAAP01003860.1_30 - 1.4e-90 303.0 0.2 1.6e-90 302.8 0.2 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AAAP01003860.1_30 - 6.2e-09 35.6 0.4 8.7e-09 35.1 0.4 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AAAP01003860.1_30 - 1.8 8.0 8.1 5.6 6.4 8.1 1.9 1 1 0 1 1 1 0 Carbohydrate kinase HK PF02110.15 AAAP01003860.1_30 - 2.2 7.6 6.9 5.8 6.2 0.1 2.4 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family CxxCxxCC PF03692.15 AAAP01003860.1_31 - 1.8e-06 28.5 1.7 2.8e-06 27.9 1.7 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Aminotran_5 PF00266.19 AAAP01003860.1_32 - 2.8e-05 23.2 0.0 4.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V 2-Hacid_dh_C PF02826.19 AAAP01003860.1_33 - 2.6e-63 212.6 0.0 4.5e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01003860.1_33 - 3.6e-38 130.3 0.6 3.6e-38 130.3 0.6 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 AAAP01003860.1_33 - 8.8e-09 35.0 0.0 2.9e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 AAAP01003860.1_33 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 AAAP01003860.1_33 - 0.00059 19.9 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HutP PF09021.11 AAAP01003860.1_33 - 0.012 15.9 0.8 0.058 13.7 0.0 2.6 3 0 0 3 3 3 0 HutP NAD_binding_2 PF03446.15 AAAP01003860.1_33 - 0.02 15.1 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TMP-TENI PF02581.17 AAAP01003860.1_33 - 0.04 13.3 1.9 0.42 9.9 0.0 2.8 3 0 0 3 3 3 0 Thiamine monophosphate synthase MCPsignal PF00015.21 AAAP01003860.1_34 - 1.2e-36 126.2 26.5 1.2e-36 126.2 26.5 3.1 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain CZB PF13682.6 AAAP01003860.1_34 - 0.00027 21.3 0.1 0.00056 20.3 0.1 1.5 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain DUF1664 PF07889.12 AAAP01003860.1_34 - 0.012 15.7 10.9 0.53 10.3 0.7 4.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAAP01003860.1_34 - 0.015 15.5 3.9 1.3 9.4 0.7 4.1 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 AAAP01003860.1_34 - 0.44 11.1 8.4 10 6.6 0.4 4.4 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 AAAP01003860.1_34 - 0.52 10.6 17.7 11 6.3 0.6 4.7 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) tRNA-synt_His PF13393.6 AAAP01003860.1_35 - 3.8e-89 299.0 0.2 4.4e-89 298.8 0.2 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase SUKH-4 PF14435.6 AAAP01003860.1_35 - 0.12 12.4 3.9 1.6 8.7 0.0 2.5 2 1 0 2 2 2 0 SUKH-4 immunity protein Adenylsucc_synt PF00709.21 AAAP01003860.1_36 - 3e-173 576.6 0.0 3.5e-173 576.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Pkinase PF00069.25 AAAP01003860.1_37 - 8.8e-05 22.0 0.0 0.00052 19.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Acyl_transf_3 PF01757.22 AAAP01003860.1_38 - 0.022 13.8 6.1 0.028 13.5 6.1 1.0 1 0 0 1 1 1 0 Acyltransferase family MCPsignal PF00015.21 AAAP01003860.1_39 - 2.6e-33 115.3 29.6 2.6e-33 115.3 29.6 3.0 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003860.1_39 - 3.7e-10 40.0 5.9 1.3e-09 38.2 0.0 4.6 5 1 0 5 5 4 1 HAMP domain Rx_N PF18052.1 AAAP01003860.1_39 - 0.00051 20.3 0.4 0.0077 16.5 0.4 2.9 1 1 1 2 2 2 1 Rx N-terminal domain 4HB_MCP_1 PF12729.7 AAAP01003860.1_39 - 0.0093 15.5 2.2 0.0093 15.5 2.2 3.8 3 2 0 3 3 3 1 Four helix bundle sensory module for signal transduction DUF1664 PF07889.12 AAAP01003860.1_39 - 0.015 15.4 4.3 0.015 15.4 4.3 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 AAAP01003860.1_39 - 0.038 14.4 9.4 0.74 10.2 0.3 4.1 3 1 1 4 4 4 0 Syntaxin-like protein DUF3042 PF11240.8 AAAP01003860.1_39 - 0.063 13.3 0.9 1.9 8.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) BLOC1_2 PF10046.9 AAAP01003860.1_39 - 0.13 12.6 8.9 4.7 7.6 0.8 4.1 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 AAAP01003860.1_39 - 0.25 11.2 4.3 0.46 10.3 0.7 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 AAAP01003860.1_39 - 0.64 10.3 37.9 0.06 13.6 1.4 5.7 5 1 1 6 6 5 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 AAAP01003860.1_39 - 0.69 9.1 3.1 1.9 7.7 0.7 2.4 2 0 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 AAAP01003860.1_39 - 1.3 9.1 22.0 1.3 9.1 7.8 3.7 2 2 2 4 4 4 0 Laminin Domain II AAA_13 PF13166.6 AAAP01003860.1_39 - 1.6 7.3 11.5 3.2 6.3 11.0 1.8 1 1 0 1 1 1 0 AAA domain LXG PF04740.12 AAAP01003860.1_39 - 1.6 8.4 12.8 0.14 11.8 4.7 2.7 3 0 0 3 3 2 0 LXG domain of WXG superfamily Sec34 PF04136.15 AAAP01003860.1_39 - 2.2 8.2 5.1 39 4.1 0.2 3.2 2 1 1 3 3 3 0 Sec34-like family Baculo_PEP_C PF04513.12 AAAP01003860.1_39 - 4 7.5 21.5 1.2 9.2 11.3 3.5 2 1 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.13 AAAP01003860.1_39 - 4.3 6.3 14.2 26 3.8 13.8 2.1 1 1 0 1 1 1 0 Actin interacting protein 3 DUF3450 PF11932.8 AAAP01003860.1_39 - 4.5 6.5 17.2 0.26 10.5 6.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 AAAP01003860.1_39 - 4.6 6.9 20.6 7.1 6.2 3.2 3.4 1 1 2 3 3 3 0 Laminin Domain I Lipase_GDSL_2 PF13472.6 AAAP01003860.1_39 - 4.8 7.5 6.2 2.1 8.7 0.1 3.1 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ERM PF00769.19 AAAP01003860.1_39 - 7.6 6.3 10.5 6.7 6.4 1.6 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Sec8_exocyst PF04048.14 AAAP01003860.1_39 - 7.8 6.4 8.7 11 5.9 0.9 2.7 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DASH_Dad2 PF08654.10 AAAP01003860.1_39 - 7.8 7.0 14.7 2.8 8.4 4.6 4.1 3 2 0 3 3 3 0 DASH complex subunit Dad2 Fib_alpha PF08702.10 AAAP01003860.1_39 - 8.1 6.6 8.9 3.1 8.0 2.1 2.9 3 1 0 3 3 2 0 Fibrinogen alpha/beta chain family Sigma70_r2 PF04542.14 AAAP01003860.1_40 - 6.1e-18 64.3 0.1 2e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AAAP01003860.1_40 - 4.5e-17 61.3 2.8 4.5e-17 61.3 2.8 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AAAP01003860.1_40 - 2.7e-07 30.5 0.1 2.7e-07 30.5 0.1 2.5 3 0 0 3 3 3 1 Sigma-70 factor, region 1.2 HTH_19 PF12844.7 AAAP01003860.1_40 - 0.00064 19.7 0.2 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r3 PF04539.16 AAAP01003860.1_40 - 0.00066 19.7 3.3 0.011 15.8 0.6 2.4 2 0 0 2 2 2 1 Sigma-70 region 3 HTH_3 PF01381.22 AAAP01003860.1_40 - 0.0093 16.0 0.5 0.99 9.5 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix UCR_14kD PF02271.16 AAAP01003860.1_40 - 0.02 14.8 0.0 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit HTH_25 PF13413.6 AAAP01003860.1_40 - 0.021 14.7 0.2 0.38 10.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 AAAP01003860.1_40 - 0.026 14.5 1.1 0.087 12.8 0.5 2.1 2 0 0 2 2 2 0 HTH domain LysM PF01476.20 AAAP01003860.1_40 - 0.034 14.2 0.0 8.7 6.5 0.0 2.9 3 0 0 3 3 3 0 LysM domain PseudoU_synth_2 PF00849.22 AAAP01003860.1_41 - 1.3e-37 129.3 0.0 1.8e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AAAP01003860.1_41 - 7.2e-08 32.0 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain Prok-JAB PF14464.6 AAAP01003860.1_43 - 7.8e-22 77.3 0.4 9.4e-22 77.0 0.4 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 AAAP01003860.1_43 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RadC PF04002.15 AAAP01003860.1_43 - 0.22 11.5 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain HisKA PF00512.25 AAAP01003861.1_1 - 1.3e-18 66.7 1.0 2.9e-18 65.7 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 AAAP01003861.1_1 - 1.9e-12 47.5 0.0 7.2e-12 45.6 0.0 1.6 1 1 1 2 2 2 2 Cache domain sCache_2 PF17200.4 AAAP01003861.1_2 - 2.9e-06 27.2 0.0 4.2e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003861.1_2 - 0.00076 18.7 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Cache domain Peptidase_S15 PF02129.18 AAAP01003861.1_3 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 AAAP01003861.1_3 - 1.3e-06 27.9 0.0 7.2e-06 25.4 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAAP01003861.1_3 - 6.5e-06 26.9 1.7 9.4e-06 26.4 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAAP01003861.1_3 - 2.1e-05 24.1 0.1 5.6e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 AAAP01003861.1_3 - 2.1e-05 24.2 0.0 9.2e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 AAAP01003861.1_3 - 0.00098 18.8 0.0 0.0091 15.7 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 AAAP01003861.1_3 - 0.0095 14.6 0.2 0.039 12.6 0.2 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 AAAP01003861.1_3 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF4189 PF13827.6 AAAP01003861.1_3 - 0.11 13.0 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) Beta-lactamase PF00144.24 AAAP01003861.1_4 - 2.1e-50 171.9 0.7 2.4e-50 171.6 0.7 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 AAAP01003861.1_4 - 3.7e-05 23.4 0.0 0.007 16.0 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family HTH_IclR PF09339.10 AAAP01003861.1_4 - 0.073 12.9 0.1 6.8 6.6 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Peptidase_S11 PF00768.20 AAAP01003861.1_4 - 0.12 11.8 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Med25_NR-box PF11244.8 AAAP01003861.1_4 - 0.2 12.1 0.6 10 6.6 0.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing PhnA PF03831.14 AAAP01003861.1_5 - 1.2e-32 111.6 5.4 1.4e-32 111.3 5.4 1.1 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 AAAP01003861.1_5 - 2.6e-14 52.9 5.4 4e-14 52.3 5.4 1.3 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AAAP01003861.1_5 - 0.00032 20.1 0.5 0.0007 19.1 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 AAAP01003861.1_5 - 0.0015 18.4 1.8 0.0016 18.3 0.6 1.7 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Zn_Tnp_IS1 PF03811.13 AAAP01003861.1_5 - 0.017 14.9 2.2 0.034 13.9 0.1 2.3 2 0 0 2 2 2 0 InsA N-terminal domain DUF4469 PF14734.6 AAAP01003861.1_5 - 0.035 14.3 0.2 0.048 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold PADR1 PF08063.12 AAAP01003861.1_5 - 0.056 13.2 1.4 0.11 12.2 1.4 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain A2L_zn_ribbon PF08792.10 AAAP01003861.1_5 - 0.058 13.1 0.7 0.11 12.2 0.7 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2318 PF10080.9 AAAP01003861.1_5 - 0.09 12.9 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.18 AAAP01003861.1_5 - 0.33 10.8 4.7 4 7.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Anti-TRAP PF15777.5 AAAP01003861.1_5 - 0.4 10.7 2.6 5.3 7.1 0.4 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein UPF0547 PF10571.9 AAAP01003861.1_5 - 1.2 9.3 9.1 4.1 7.6 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ISL3 PF14690.6 AAAP01003861.1_5 - 1.8 9.3 4.8 5.6 7.7 0.2 2.8 2 2 2 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF4379 PF14311.6 AAAP01003861.1_5 - 2.4 8.6 7.4 0.21 12.0 1.1 2.1 1 1 0 2 2 2 0 Probable Zinc-ribbon domain Rubredoxin_2 PF18073.1 AAAP01003861.1_5 - 10 6.0 8.6 4.1 7.2 1.4 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Na_sulph_symp PF00939.19 AAAP01003861.1_6 - 5.5e-116 388.4 48.5 6.2e-116 388.2 48.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AAAP01003861.1_6 - 3.3e-15 56.1 64.7 1.9e-08 33.9 23.4 2.6 1 1 2 3 3 3 2 Citrate transporter HATPase_c PF02518.26 AAAP01003861.1_8 - 7.2e-19 68.4 0.0 1.7e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003861.1_8 - 1.3e-10 41.5 0.2 5.9e-10 39.4 0.2 2.3 1 0 0 1 1 1 1 HAMP domain PAS_4 PF08448.10 AAAP01003861.1_8 - 2.2e-07 31.1 0.0 7e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003861.1_8 - 3.7e-05 23.7 0.8 0.00055 19.9 0.0 3.2 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003861.1_8 - 0.0008 19.4 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003861.1_8 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Phosphonate-bd PF12974.7 AAAP01003861.1_9 - 1.6e-47 162.2 0.1 1.8e-47 162.0 0.1 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAAP01003861.1_9 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like Response_reg PF00072.24 AAAP01003861.1_10 - 1.5e-20 73.4 0.0 3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HD_5 PF13487.6 AAAP01003861.1_10 - 2.3e-19 69.4 0.0 1.2e-18 67.1 0.0 2.1 3 0 0 3 3 3 1 HD domain HDOD PF08668.12 AAAP01003861.1_11 - 5.1e-42 143.6 0.0 6.8e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Response_reg PF00072.24 AAAP01003861.1_11 - 5.6e-12 45.8 0.0 1.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain RecJ_OB PF17768.1 AAAP01003861.1_13 - 4.4e-23 81.6 0.0 6.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RecJ OB domain DHHA1 PF02272.19 AAAP01003861.1_13 - 2.9e-20 73.1 0.5 5.5e-20 72.2 0.5 1.4 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 AAAP01003861.1_13 - 2.2e-08 34.2 0.0 1.1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 DHH family Peripla_BP_6 PF13458.6 AAAP01003861.1_13 - 4.9e-06 26.4 0.4 1e-05 25.4 0.4 1.4 1 0 0 1 1 1 1 Periplasmic binding protein ThiG PF05690.14 AAAP01003861.1_13 - 0.0076 15.6 0.8 0.019 14.3 0.8 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Nitro_FeMo-Co PF02579.17 AAAP01003861.1_13 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Toprim PF01751.22 AAAP01003861.1_13 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Toprim domain FBPase_glpX PF03320.13 AAAP01003861.1_14 - 5.6e-117 390.0 5.9 6.3e-117 389.8 5.9 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Homoserine_dh PF00742.19 AAAP01003861.1_15 - 5.1e-65 218.6 0.0 1.3e-64 217.3 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 AAAP01003861.1_15 - 5.9e-12 46.3 0.7 1.2e-11 45.3 0.7 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 AAAP01003861.1_15 - 4.5e-10 39.1 0.0 9.7e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AAAP01003861.1_15 - 0.0017 18.9 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain Aminotran_1_2 PF00155.21 AAAP01003861.1_16 - 1e-54 186.2 0.0 1.1e-54 186.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OmpA PF00691.20 AAAP01003861.1_17 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 OmpA family Pilus_CpaD PF09476.10 AAAP01003861.1_17 - 0.077 12.7 1.1 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) PhaC_N PF07167.13 AAAP01003861.1_18 - 2.2e-78 261.8 0.4 6.6e-78 260.3 0.1 1.7 2 0 0 2 2 2 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.20 AAAP01003861.1_19 - 1.3e-12 47.9 0.0 2.5e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3141 PF11339.8 AAAP01003861.1_19 - 0.00081 17.9 0.0 0.001 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) DLH PF01738.18 AAAP01003861.1_19 - 0.0016 18.0 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF5596 PF18082.1 AAAP01003861.1_19 - 0.96 9.3 3.3 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) PAS_4 PF08448.10 AAAP01003861.1_20 - 1.4e-31 109.0 3.0 5.6e-18 65.2 0.1 2.9 3 0 0 3 3 2 2 PAS fold PAS PF00989.25 AAAP01003861.1_20 - 5e-25 87.7 0.0 2.8e-16 59.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAAP01003861.1_20 - 1.1e-24 87.1 0.0 3.3e-24 85.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AAAP01003861.1_20 - 4.8e-19 68.5 0.0 5.4e-10 39.5 0.0 2.9 2 0 0 2 2 2 2 PAS domain GAF_2 PF13185.6 AAAP01003861.1_20 - 6.1e-15 55.7 4.5 2.1e-11 44.3 0.1 3.7 4 0 0 4 4 4 2 GAF domain HisKA PF00512.25 AAAP01003861.1_20 - 4.3e-12 45.9 0.6 4.3e-12 45.9 0.6 2.8 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003861.1_20 - 3e-11 43.1 0.1 1.4e-06 28.1 0.0 2.8 2 0 0 2 2 2 2 PAS domain GAF PF01590.26 AAAP01003861.1_20 - 5.2e-11 43.3 3.4 1.3e-07 32.3 0.3 2.8 2 1 0 2 2 2 2 GAF domain GAF_3 PF13492.6 AAAP01003861.1_20 - 7e-11 42.6 0.1 9.8e-10 38.9 0.0 2.7 3 0 0 3 3 3 1 GAF domain PAS_7 PF12860.7 AAAP01003861.1_20 - 7.4e-07 29.3 0.0 0.00099 19.3 0.0 3.6 2 1 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 AAAP01003861.1_20 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01003861.1_20 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AAAP01003861.1_20 - 0.005 17.4 0.0 0.2 12.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain SpoVT_C PF15714.5 AAAP01003861.1_20 - 0.0084 16.2 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor dCache_1 PF02743.18 AAAP01003861.1_21 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cache domain SPOR PF05036.13 AAAP01003861.1_22 - 0.00023 21.4 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Sporulation related domain Ni_hydr_CYTB PF01292.20 AAAP01003861.1_23 - 4.8e-29 101.3 9.6 5.4e-29 101.1 9.6 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF2231 PF09990.9 AAAP01003861.1_23 - 0.026 15.0 8.1 0.027 14.9 2.0 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2231) Cytochrom_B561 PF03188.16 AAAP01003861.1_23 - 0.034 14.3 1.0 0.034 14.3 1.0 2.0 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 AAAP01003861.1_23 - 0.11 12.6 7.1 0.36 11.0 0.3 2.7 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF4405 PF14358.6 AAAP01003861.1_23 - 0.52 10.9 11.0 0.2 12.3 2.1 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4405) Cytidylate_kin2 PF13189.6 AAAP01003861.1_24 - 8.8e-40 136.7 0.0 1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family MCPsignal PF00015.21 AAAP01003861.1_25 - 1.3e-27 96.7 10.6 1.3e-27 96.7 10.6 3.0 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003861.1_25 - 1.6e-06 28.2 6.7 0.069 13.4 0.1 4.5 2 2 3 5 5 5 2 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 AAAP01003861.1_25 - 0.00091 19.3 1.5 2.3 8.3 0.1 3.5 2 2 1 3 3 3 2 Protein of unknown function (DUF1664) Laminin_II PF06009.12 AAAP01003861.1_25 - 0.0014 18.6 0.7 5.4 7.0 0.1 3.7 2 1 1 3 3 3 1 Laminin Domain II Vps53_N PF04100.12 AAAP01003861.1_25 - 0.1 11.5 0.3 0.97 8.3 0.1 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal DivIVA PF05103.13 AAAP01003861.1_25 - 0.12 12.5 0.7 0.67 10.0 0.1 2.5 2 1 1 3 3 3 0 DivIVA protein NPV_P10 PF05531.12 AAAP01003861.1_25 - 0.15 12.5 4.2 13 6.3 0.0 4.2 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.13 AAAP01003861.1_25 - 0.18 10.4 0.3 9.3 4.8 0.1 2.7 2 1 2 4 4 4 0 Tweety RrnaAD PF00398.20 AAAP01003861.1_27 - 4.5e-47 160.3 0.0 5.1e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AAAP01003861.1_27 - 0.00038 21.1 0.0 0.00072 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003861.1_27 - 0.037 14.7 0.0 0.07 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PdxA PF04166.12 AAAP01003861.1_28 - 1.3e-99 333.2 0.0 1.5e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA BtrH_N PF14399.6 AAAP01003861.1_28 - 0.19 12.0 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Rotamase PF00639.21 AAAP01003861.1_29 - 4.1e-21 75.7 0.0 3.7e-17 63.1 0.0 3.1 2 1 0 2 2 2 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AAAP01003861.1_29 - 1.6e-17 64.1 0.0 1.5e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain SurA_N PF09312.11 AAAP01003861.1_29 - 1.5e-15 57.3 2.9 2.7e-15 56.5 2.0 1.9 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_3 PF13624.6 AAAP01003861.1_29 - 5.4e-10 39.3 0.1 1.4e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 SurA N-terminal domain Rotamase_2 PF13145.6 AAAP01003861.1_29 - 5.7e-07 30.4 0.0 0.0005 20.9 0.0 2.8 3 0 0 3 3 3 2 PPIC-type PPIASE domain SurA_N_2 PF13623.6 AAAP01003861.1_29 - 0.0001 22.2 0.1 0.00034 20.5 0.0 1.9 2 0 0 2 2 2 1 SurA N-terminal domain LptD PF04453.14 AAAP01003861.1_30 - 6.6e-46 157.3 0.3 8.8e-46 156.9 0.3 1.1 1 0 0 1 1 1 1 LPS transport system D OstA PF03968.14 AAAP01003861.1_30 - 0.041 14.1 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 OstA-like protein OstA_2 PF13100.6 AAAP01003861.1_30 - 0.06 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 OstA-like protein LptC PF06835.13 AAAP01003861.1_30 - 0.16 11.5 0.0 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide-assembly, LptC-related Phage_pRha PF09669.10 AAAP01003862.1_2 - 1.3e-17 64.2 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Vps5 PF09325.10 AAAP01003862.1_4 - 0.029 13.9 1.8 2.4 7.6 1.0 2.2 1 1 1 2 2 2 0 Vps5 C terminal like HMGL-like PF00682.19 AAAP01003862.1_4 - 0.044 13.3 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 HMGL-like DUF1664 PF07889.12 AAAP01003862.1_4 - 0.079 13.0 3.1 32 4.6 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 AAAP01003862.1_4 - 0.09 13.0 0.9 0.24 11.6 0.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_U32 PF01136.19 AAAP01003862.1_5 - 2.9e-16 59.3 0.0 3.7e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32 PF01136.19 AAAP01003862.1_6 - 1.5e-61 207.5 0.0 2e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family U32 SCP2 PF02036.17 AAAP01003862.1_7 - 3e-10 40.5 0.0 4.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family cNMP_binding PF00027.29 AAAP01003862.1_8 - 2.1e-21 75.8 0.1 8.9e-21 73.8 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Response_reg PF00072.24 AAAP01003862.1_8 - 2.3e-21 76.1 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DnaJ PF00226.31 AAAP01003862.1_9 - 4.8e-18 65.0 0.0 7.4e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain SH3_3 PF08239.11 AAAP01003862.1_9 - 4.1e-06 27.0 0.0 8.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain ComX PF05952.12 AAAP01003862.1_10 - 0.079 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX CbiA PF01656.23 AAAP01003862.1_11 - 4.9e-17 62.2 0.0 6.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AAAP01003862.1_11 - 2.2e-13 50.2 1.5 6.3e-11 42.2 1.5 2.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 AAAP01003862.1_11 - 4e-11 43.1 0.0 9.3e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 AAAP01003862.1_11 - 6.3e-11 42.2 0.0 3.7e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AAAP01003862.1_11 - 7.2e-06 25.4 0.2 0.00042 19.6 0.2 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AAAP01003862.1_11 - 0.00064 19.3 0.3 0.0048 16.4 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 AAAP01003862.1_11 - 0.00092 18.6 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 VirC1 protein IstB_IS21 PF01695.17 AAAP01003862.1_11 - 0.0023 17.7 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein CLP1_P PF16575.5 AAAP01003862.1_11 - 0.026 14.3 0.1 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MipZ PF09140.11 AAAP01003862.1_11 - 0.036 13.4 0.7 0.064 12.5 0.1 1.6 2 0 0 2 2 2 0 ATPase MipZ AAA_25 PF13481.6 AAAP01003862.1_11 - 0.043 13.4 2.4 0.076 12.6 0.1 2.4 3 1 0 3 3 3 0 AAA domain APS_kinase PF01583.20 AAAP01003862.1_11 - 0.057 13.3 0.4 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 AAAP01003862.1_11 - 0.13 12.0 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01003862.1_12 - 2.6e-22 79.4 0.0 3.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 AAAP01003862.1_12 - 1.8e-05 24.6 0.0 0.00054 19.7 0.0 2.5 2 1 0 2 2 2 1 IstB-like ATP binding protein ALF PF03752.13 AAAP01003862.1_12 - 0.0017 18.3 0.2 0.0098 15.8 0.2 2.4 1 0 0 1 1 1 1 Short repeats of unknown function AAA_33 PF13671.6 AAAP01003862.1_12 - 0.0019 18.4 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003862.1_12 - 0.0037 17.7 0.5 0.013 15.8 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 AAAP01003862.1_12 - 0.013 15.4 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase CLP1_P PF16575.5 AAAP01003862.1_12 - 0.022 14.5 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 AAAP01003862.1_12 - 0.027 14.0 0.6 0.39 10.3 0.6 2.6 1 1 0 1 1 1 0 AAA domain DUF3700 PF12481.8 AAAP01003862.1_12 - 0.084 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein Zeta_toxin PF06414.12 AAAP01003862.1_12 - 0.096 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 AAAP01003862.1_12 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01003862.1_12 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AAAP01003862.1_12 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 AAAP01003862.1_12 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003862.1_12 - 0.24 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain FHIPEP PF00771.20 AAAP01003862.1_13 - 6.2e-264 877.5 6.7 7.4e-264 877.2 6.7 1.0 1 0 0 1 1 1 1 FHIPEP family DFF-C PF09033.10 AAAP01003862.1_13 - 0.035 14.0 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Competence PF03772.16 AAAP01003862.1_13 - 0.33 10.2 19.5 0.012 14.9 13.4 1.6 2 0 0 2 2 2 0 Competence protein DUF5423 PF17461.2 AAAP01003862.1_13 - 7.1 5.4 8.2 24 3.6 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5423) Sigma54_activat PF00158.26 AAAP01003862.1_14 - 3.5e-71 238.3 0.2 5e-71 237.8 0.2 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AAAP01003862.1_14 - 4.3e-20 72.2 0.0 1.5e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AAAP01003862.1_14 - 7.6e-16 57.6 0.0 2.8e-15 55.8 0.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AAAP01003862.1_14 - 1.2e-07 31.8 0.1 1.9e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Response_reg PF00072.24 AAAP01003862.1_14 - 4.6e-06 26.8 0.1 1.2e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 Response regulator receiver domain AAA PF00004.29 AAAP01003862.1_14 - 7.3e-06 26.4 0.0 1.8e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 AAAP01003862.1_14 - 9.6e-05 22.3 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01003862.1_14 - 0.0015 18.3 1.3 0.0043 16.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain HTH_50 PF18024.1 AAAP01003862.1_14 - 0.0031 17.1 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain ADH_zinc_N PF00107.26 AAAP01003862.1_14 - 0.0035 17.3 0.8 0.47 10.4 0.0 2.5 1 1 1 2 2 2 2 Zinc-binding dehydrogenase MCM PF00493.23 AAAP01003862.1_14 - 0.0037 16.4 0.1 0.0082 15.3 0.1 1.5 1 1 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 AAAP01003862.1_14 - 0.0039 16.6 0.1 0.93 8.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_28 PF13518.6 AAAP01003862.1_14 - 0.0047 17.0 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01003862.1_14 - 0.0073 15.7 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 AAA_19 PF13245.6 AAAP01003862.1_14 - 0.012 15.9 0.0 0.35 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAAP01003862.1_14 - 0.018 15.3 0.0 0.052 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AAAP01003862.1_14 - 0.045 13.9 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 AAAP01003862.1_14 - 0.048 13.0 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 AAAP01003862.1_14 - 0.049 14.0 0.1 0.19 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain HTH_23 PF13384.6 AAAP01003862.1_14 - 0.06 13.2 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 1 0 Homeodomain-like domain AAA_7 PF12775.7 AAAP01003862.1_14 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_29 PF13551.6 AAAP01003862.1_14 - 0.082 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix AAA_PrkA PF08298.11 AAAP01003862.1_14 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain FliMN_C PF01052.20 AAAP01003862.1_15 - 2.4e-25 88.3 3.0 3e-25 88.0 3.0 1.1 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term DUF1839 PF08893.10 AAAP01003862.1_15 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) FliH PF02108.16 AAAP01003862.1_16 - 3.2e-13 49.9 2.8 3.3e-13 49.8 1.8 1.5 2 0 0 2 2 2 1 Flagellar assembly protein FliH T6SS_VasJ PF16989.5 AAAP01003862.1_16 - 0.0029 17.1 0.9 0.0041 16.6 0.9 1.2 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Anti-adapt_IraP PF10796.9 AAAP01003862.1_16 - 0.0037 17.8 0.2 0.084 13.4 0.3 2.3 2 1 0 2 2 2 1 Sigma-S stabilisation anti-adaptor protein PspA_IM30 PF04012.12 AAAP01003862.1_16 - 0.031 13.9 5.5 0.046 13.3 5.5 1.2 1 0 0 1 1 1 0 PspA/IM30 family zf-Dof PF02701.15 AAAP01003862.1_16 - 0.22 11.7 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Dof domain, zinc finger TetR_C_15 PF17918.1 AAAP01003862.1_16 - 1.9 9.3 8.9 0.76 10.6 5.5 2.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FliG_C PF01706.16 AAAP01003862.1_17 - 2.4e-41 140.3 15.3 5.7e-39 132.7 2.6 4.6 2 1 3 5 5 5 2 FliG C-terminal domain FliG_N PF14842.6 AAAP01003862.1_17 - 1.4e-32 112.3 9.6 5.6e-25 87.9 0.0 3.6 2 1 2 4 4 4 2 FliG N-terminal domain FliG_M PF14841.6 AAAP01003862.1_17 - 1.5e-30 105.3 1.6 3.4e-24 84.8 0.6 3.0 3 0 0 3 3 3 2 FliG middle domain MgtE_N PF03448.17 AAAP01003862.1_17 - 1.5e-08 35.1 8.0 0.00039 21.0 2.7 4.8 3 1 1 4 4 4 2 MgtE intracellular N domain IFT81_CH PF18383.1 AAAP01003862.1_17 - 0.011 16.0 0.2 0.023 14.9 0.2 1.5 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain STAS PF01740.21 AAAP01003862.1_17 - 0.017 14.8 0.1 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 STAS domain STAS_2 PF13466.6 AAAP01003862.1_17 - 0.074 13.4 0.1 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 STAS domain AAA_16 PF13191.6 AAAP01003862.1_17 - 0.086 13.2 0.4 0.18 12.2 0.2 1.7 2 0 0 2 2 2 0 AAA ATPase domain YscJ_FliF PF01514.17 AAAP01003862.1_18 - 1.2e-64 217.5 0.4 3.8e-64 215.9 0.0 2.0 2 1 0 2 2 2 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AAAP01003862.1_18 - 9.2e-40 136.4 10.8 9.2e-40 136.4 10.8 2.1 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal Flg_bbr_C PF06429.13 AAAP01003862.1_19 - 8.4e-16 57.9 1.7 8.9e-16 57.8 1.7 1.0 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01003862.1_20 - 2.1e-07 30.7 0.5 8.5e-07 28.8 0.5 2.2 1 0 0 1 1 1 1 Flagella basal body rod protein FlaE PF07559.14 AAAP01003862.1_20 - 0.00054 20.5 43.1 2.2e+02 2.4 34.4 5.0 2 2 0 2 2 2 0 Flagellar basal body protein FlaE FlgD PF03963.14 AAAP01003862.1_21 - 1.9e-21 76.2 11.6 1.9e-21 76.2 11.6 2.7 3 0 0 3 3 3 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AAAP01003862.1_21 - 1.7e-18 66.2 1.2 1.7e-18 66.2 1.2 2.1 2 0 0 2 2 2 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AAAP01003862.1_21 - 4.4e-10 39.6 0.0 1.4e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 FlgD Tudor-like domain DUF2271 PF10029.9 AAAP01003862.1_21 - 0.00034 20.3 0.6 0.00034 20.3 0.6 2.0 2 0 0 2 2 2 1 Predicted periplasmic protein (DUF2271) Flg_hook PF02120.16 AAAP01003862.1_22 - 5.9e-18 64.5 7.3 7.1e-18 64.3 0.2 3.0 2 1 0 2 2 2 1 Flagellar hook-length control protein FliK DUF2664 PF10867.8 AAAP01003862.1_22 - 0.031 14.7 2.0 0.33 11.4 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) DUF5063 PF16702.5 AAAP01003862.1_22 - 0.14 12.6 0.5 0.27 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) HZS_alpha PF18582.1 AAAP01003862.1_22 - 1.4 9.5 3.9 0.85 10.1 0.1 2.7 3 0 0 3 3 3 0 Hydrazine synthase alpha subunit middle domain MoCF_biosynth PF00994.24 AAAP01003862.1_24 - 1e-31 109.6 0.1 1.4e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain YAcAr PF10686.9 AAAP01003862.1_24 - 0.059 13.3 0.3 0.18 11.8 0.2 1.9 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Acetyltransf_3 PF13302.7 AAAP01003862.1_25 - 6.3e-31 107.9 0.1 1.3e-30 106.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 AAAP01003862.1_25 - 5e-19 68.6 0.0 1.6e-18 67.0 0.0 1.8 3 0 0 3 3 3 1 NUDIX domain NUDIX_4 PF14815.6 AAAP01003862.1_25 - 4.2e-18 65.3 0.0 9.7e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 AAAP01003862.1_25 - 8.6e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAAP01003862.1_25 - 0.075 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ArgJ PF01960.18 AAAP01003862.1_26 - 2.4e-134 447.8 11.0 2.7e-134 447.6 11.0 1.0 1 0 0 1 1 1 1 ArgJ family Rotamase_3 PF13616.6 AAAP01003862.1_27 - 9.7e-25 87.4 0.0 2.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AAAP01003862.1_27 - 2.7e-22 79.5 0.0 9.1e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AAAP01003862.1_27 - 9.3e-18 65.2 0.6 1.7e-17 64.3 0.1 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Gp_dh_C PF02800.20 AAAP01003862.1_28 - 4.7e-68 227.7 0.0 6.6e-68 227.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AAAP01003862.1_28 - 6.5e-38 129.1 0.0 1.2e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAAP01003862.1_28 - 0.08 13.8 0.0 0.31 11.9 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 AAAP01003862.1_28 - 0.084 13.0 0.2 0.29 11.3 0.2 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PGK PF00162.19 AAAP01003862.1_29 - 9.3e-147 488.9 0.4 1.1e-146 488.7 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TP_methylase PF00590.20 AAAP01003862.1_30 - 1.7e-41 142.5 0.6 2e-41 142.3 0.6 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 AAAP01003862.1_30 - 0.049 14.0 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily TP_methylase PF00590.20 AAAP01003862.1_31 - 2.2e-43 148.7 3.0 2.5e-43 148.5 3.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DsbD_2 PF13386.6 AAAP01003862.1_32 - 5.6e-35 121.1 29.5 7e-35 120.8 29.5 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region SCO1-SenC PF02630.14 AAAP01003862.1_33 - 3.1e-52 176.1 0.0 3.7e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 AAAP01003862.1_33 - 9.7e-08 32.0 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AAAP01003862.1_33 - 0.00026 21.3 0.0 0.00045 20.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like GATase_3 PF07685.14 AAAP01003862.1_34 - 2.1e-29 102.5 0.0 2.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 AAAP01003862.1_34 - 1.6e-15 57.5 0.0 7e-09 35.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain CbiA PF01656.23 AAAP01003862.1_34 - 3.9e-14 52.8 0.0 5.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 AAAP01003862.1_34 - 0.0074 16.2 0.1 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PHB_depo_C PF06850.11 AAAP01003862.1_35 - 3.6e-96 320.5 0.1 5.2e-96 319.9 0.1 1.2 1 0 0 1 1 1 1 PHB de-polymerase C-terminus Radical_SAM_C PF16199.5 AAAP01003862.1_35 - 0.061 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Lsm_C PF14894.6 AAAP01003862.1_35 - 0.16 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Lsm C-terminal CxxCxxCC PF03692.15 AAAP01003862.1_36 - 2e-07 31.6 5.6 3.4e-07 30.8 5.6 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain GCS2 PF04107.13 AAAP01003862.1_37 - 1.2e-94 317.0 0.0 1.5e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Asp_decarbox PF02261.16 AAAP01003862.1_38 - 2.2e-37 127.5 0.0 2.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate decarboxylase QueC PF06508.13 AAAP01003862.1_39 - 1.3e-74 250.2 0.0 1.5e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAAP01003862.1_39 - 3.2e-07 30.3 0.1 4.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 AAAP01003862.1_39 - 0.039 13.5 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Radical_SAM PF04055.21 AAAP01003862.1_39 - 0.074 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily tRNA_Me_trans PF03054.16 AAAP01003862.1_39 - 0.21 10.3 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase HupF_HypC PF01455.18 AAAP01003863.1_2 - 2.6e-17 62.7 0.4 3e-17 62.5 0.4 1.1 1 0 0 1 1 1 1 HupF/HypC family DUF2748 PF10871.8 AAAP01003863.1_3 - 0.17 10.5 1.3 0.24 10.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) NiFeSe_Hases PF00374.19 AAAP01003863.1_4 - 2.6e-10 39.8 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Nickel-dependent hydrogenase HypA PF01155.19 AAAP01003863.1_5 - 3.5e-34 117.2 0.4 3.9e-34 117.0 0.4 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 AAAP01003863.1_5 - 4.5e-05 23.6 1.2 9.2e-05 22.6 1.2 1.5 1 0 0 1 1 1 1 zinc-ribbon DZR PF12773.7 AAAP01003863.1_5 - 0.0086 16.1 0.2 0.016 15.2 0.2 1.4 1 1 0 1 1 1 1 Double zinc ribbon DUF1451 PF07295.11 AAAP01003863.1_5 - 0.019 15.0 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-TFIIB PF13453.6 AAAP01003863.1_5 - 0.042 13.2 0.3 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF1272 PF06906.11 AAAP01003863.1_5 - 0.083 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Anti-TRAP PF15777.5 AAAP01003863.1_5 - 0.12 12.4 0.9 0.22 11.5 0.9 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein NOB1_Zn_bind PF08772.11 AAAP01003863.1_5 - 0.14 12.3 0.4 0.26 11.5 0.4 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like cobW PF02492.19 AAAP01003863.1_6 - 3.6e-36 124.4 0.0 4.8e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 AAAP01003863.1_6 - 0.024 14.7 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zip PF02535.22 AAAP01003863.1_6 - 0.046 13.0 6.9 0.062 12.5 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MobB PF03205.14 AAAP01003863.1_6 - 0.067 13.1 2.1 0.34 10.8 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 AAAP01003863.1_6 - 0.17 11.8 0.0 0.54 10.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain HypF_C PF17788.1 AAAP01003863.1_7 - 7e-26 90.9 1.0 1e-25 90.3 1.0 1.3 1 0 0 1 1 1 1 HypF Kae1-like domain HupF_HypC PF01455.18 AAAP01003863.1_8 - 7.8e-26 90.0 0.0 9e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 HupF/HypC family eIF-1a PF01176.19 AAAP01003863.1_8 - 0.12 12.2 0.1 0.5 10.2 0.1 1.9 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 HypD PF01924.16 AAAP01003863.1_9 - 3.5e-157 523.0 0.0 4e-157 522.8 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family Methyltransf_4 PF02390.17 AAAP01003863.1_9 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AIRS_C PF02769.22 AAAP01003863.1_10 - 3.3e-26 92.3 0.5 5.3e-26 91.6 0.5 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AAAP01003863.1_10 - 2.9e-16 59.9 0.5 6.5e-16 58.8 0.5 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ECH_1 PF00378.20 AAAP01003863.1_11 - 3.5e-15 56.0 0.0 5.3e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_N PF00551.19 AAAP01003863.1_11 - 6.8e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AAAP01003863.1_11 - 1.2e-05 25.4 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain HI0933_like PF03486.14 AAAP01003863.1_14 - 3.2e-106 355.5 0.0 3.6e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 AAAP01003863.1_14 - 3.9e-05 23.0 0.0 0.0035 16.6 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003863.1_14 - 0.00014 22.0 0.1 0.00037 20.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AAAP01003863.1_14 - 0.00032 20.0 0.1 0.00049 19.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 AAAP01003863.1_14 - 0.0013 18.4 1.3 0.045 13.3 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AAAP01003863.1_14 - 0.0014 17.8 1.8 0.0082 15.3 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 AAAP01003863.1_14 - 0.0034 16.7 0.1 0.0061 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 AAAP01003863.1_14 - 0.0089 16.0 0.0 0.066 13.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 AAAP01003863.1_14 - 0.0094 16.5 0.0 0.19 12.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003863.1_14 - 0.047 12.8 2.6 0.091 11.8 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AAAP01003863.1_14 - 0.065 12.5 0.4 0.099 11.9 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 AAAP01003863.1_14 - 0.065 12.3 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 AAAP01003863.1_14 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 AAAP01003863.1_14 - 0.3 10.3 0.4 0.43 9.8 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PMT_2 PF13231.6 AAAP01003863.1_15 - 1.3e-27 97.0 16.0 1.3e-27 97.0 16.0 2.2 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Hemerythrin PF01814.23 AAAP01003863.1_16 - 2e-08 34.9 6.0 5.6e-08 33.5 6.0 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4167 PF13763.6 AAAP01003863.1_17 - 1.4e-31 108.4 1.7 2.5e-31 107.6 1.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4167) PaREP1 PF05942.11 AAAP01003863.1_17 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family PrmC_N PF17827.1 AAAP01003863.1_18 - 1.8e-17 63.7 1.2 8.8e-17 61.5 1.2 2.0 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 AAAP01003863.1_18 - 5.1e-13 49.1 0.0 2.1e-12 47.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAAP01003863.1_18 - 3.1e-09 36.6 0.0 6.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAAP01003863.1_18 - 1.8e-07 31.7 0.5 3.6e-06 27.6 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain PrmA PF06325.13 AAAP01003863.1_18 - 4.7e-05 22.9 0.0 8.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 AAAP01003863.1_18 - 8.6e-05 22.4 0.0 0.00093 19.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003863.1_18 - 0.00076 20.1 0.0 0.011 16.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003863.1_18 - 0.0019 18.9 4.2 0.014 16.2 0.0 3.4 4 0 0 4 4 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AAAP01003863.1_18 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 AAAP01003863.1_18 - 0.0041 16.8 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 AAAP01003863.1_18 - 0.01 15.8 0.0 0.027 14.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 AAAP01003863.1_18 - 0.044 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.8 AAAP01003863.1_18 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 AAAP01003863.1_18 - 0.18 11.4 0.5 4.2 6.9 0.1 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCRF PF03462.18 AAAP01003863.1_19 - 3.8e-69 232.4 0.3 7.2e-69 231.5 0.3 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 AAAP01003863.1_19 - 7.2e-40 135.5 1.3 1.6e-39 134.5 1.3 1.6 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 AAAP01003863.1_19 - 0.029 14.2 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 MIR domain Calpain_inhib PF00748.19 AAAP01003863.1_19 - 2.2 8.8 5.4 27 5.3 0.8 3.0 3 0 0 3 3 3 0 Calpain inhibitor GlutR_N PF05201.15 AAAP01003863.1_20 - 3e-37 127.6 0.0 5.8e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AAAP01003863.1_20 - 1.2e-29 103.2 0.0 2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AAAP01003863.1_20 - 2.2e-10 40.9 1.5 1.3e-09 38.4 1.5 2.2 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AAAP01003863.1_20 - 4.4e-06 27.2 0.4 1.8e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAAP01003863.1_20 - 0.00012 22.3 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 AAAP01003863.1_20 - 0.00014 22.3 0.0 0.00035 21.0 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.6 AAAP01003863.1_20 - 0.001 19.0 1.6 0.0023 17.8 1.6 1.7 1 0 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 AAAP01003863.1_20 - 0.0023 18.8 0.0 0.0049 17.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 AAAP01003863.1_20 - 0.013 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AAAP01003863.1_20 - 0.092 12.8 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 AAAP01003863.1_20 - 0.095 13.0 3.2 0.34 11.2 0.1 3.1 3 1 0 3 3 3 0 TrkA-N domain ThiF PF00899.21 AAAP01003863.1_20 - 0.25 10.7 2.3 0.46 9.8 1.0 2.0 1 1 1 2 2 2 0 ThiF family tRNA-synt_His PF13393.6 AAAP01003863.1_21 - 1.9e-45 155.5 0.0 2.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AAAP01003863.1_21 - 2.1e-19 70.2 0.0 4.3e-19 69.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAAP01003863.1_21 - 1.5e-12 47.5 0.1 4e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 AAAP01003863.1_21 - 9.5e-08 31.8 0.1 8.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Methyltransf_25 PF13649.6 AAAP01003863.1_22 - 7e-10 39.5 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003863.1_22 - 2.5e-09 36.9 0.0 3.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AAAP01003863.1_22 - 1.6e-07 31.9 0.0 2.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003863.1_22 - 3.5e-07 30.1 0.0 5.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003863.1_22 - 1.1e-05 26.0 0.0 1.8e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AAAP01003863.1_22 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain GcpE PF04551.14 AAAP01003863.1_23 - 3.2e-128 427.7 0.1 3.7e-128 427.5 0.1 1.0 1 0 0 1 1 1 1 GcpE protein HTH_25 PF13413.6 AAAP01003863.1_24 - 3.5e-20 71.6 0.1 6e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4115 PF13464.6 AAAP01003863.1_24 - 6e-18 64.8 0.0 1.2e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) HTH_19 PF12844.7 AAAP01003863.1_24 - 9.9e-05 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAAP01003863.1_24 - 0.00015 22.0 0.8 0.00034 20.9 0.8 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PEP-utilizers_C PF02896.18 AAAP01003863.1_25 - 1.5e-87 293.4 0.0 2.6e-87 292.6 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AAAP01003863.1_25 - 3.7e-24 85.1 0.1 1.2e-23 83.4 0.1 1.9 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AAAP01003863.1_25 - 4.6e-17 61.5 0.1 2e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain GAF_2 PF13185.6 AAAP01003863.1_25 - 2.4e-14 53.8 0.4 6.4e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 AAAP01003863.1_25 - 4.3e-11 43.6 0.9 7.2e-11 42.9 0.2 1.8 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAAP01003863.1_25 - 0.00019 21.7 0.1 0.00049 20.4 0.1 1.7 1 1 0 1 1 1 1 GAF domain NMO PF03060.15 AAAP01003863.1_26 - 1.4e-52 179.2 2.7 1.5e-32 113.3 1.7 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AAAP01003863.1_26 - 2.3e-06 27.1 2.7 3.5e-06 26.5 2.7 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 AAAP01003863.1_26 - 1.8e-05 23.9 0.1 5.5e-05 22.3 0.0 1.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AAAP01003863.1_26 - 6.3e-05 22.2 2.7 6.3e-05 22.2 2.7 2.3 1 1 1 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 AAAP01003863.1_26 - 0.00017 20.9 0.6 0.00026 20.3 0.5 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AAAP01003863.1_26 - 0.0012 18.3 0.1 0.012 15.1 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein CoA_binding_2 PF13380.6 AAAP01003863.1_26 - 0.071 13.6 0.0 4.8 7.7 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain Glu_synthase PF01645.17 AAAP01003863.1_26 - 0.14 11.2 2.5 0.17 11.0 0.3 1.9 1 1 1 2 2 2 0 Conserved region in glutamate synthase AA_kinase PF00696.28 AAAP01003863.1_27 - 6.7e-46 156.8 2.6 6.7e-46 156.8 2.6 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 AAAP01003863.1_27 - 4.1e-20 71.3 3.6 1.1e-13 50.6 0.2 3.3 4 0 0 4 4 4 2 ACT domain ACT_7 PF13840.6 AAAP01003863.1_27 - 2.2e-19 69.0 3.1 1.2e-14 53.8 0.4 2.7 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.6 AAAP01003863.1_27 - 0.03 14.3 0.1 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 ACT domain ACT_4 PF13291.6 AAAP01003863.1_27 - 1 10.0 4.8 4.9 7.8 0.1 2.9 3 0 0 3 3 3 0 ACT domain Methyltransf_23 PF13489.6 AAAP01003863.1_28 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003863.1_28 - 5.6e-19 68.6 0.1 1.2e-18 67.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003863.1_28 - 2.3e-15 57.1 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003863.1_28 - 2.6e-13 50.5 0.0 4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003863.1_28 - 9.7e-13 48.2 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01003863.1_28 - 2.7e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 AAAP01003863.1_28 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 AAAP01003863.1_28 - 0.00019 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AAAP01003863.1_28 - 0.00078 19.0 0.0 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 AAAP01003863.1_28 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AAAP01003863.1_28 - 0.0038 17.2 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AAAP01003863.1_28 - 0.028 13.3 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 AAAP01003863.1_28 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1275 PF06912.11 AAAP01003863.1_29 - 1.1e-39 136.3 14.8 1.4e-39 136.1 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1178 PF06676.11 AAAP01003863.1_30 - 2.7e-48 164.1 0.3 1.2e-47 162.1 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1178) Zn-ribbon_8 PF09723.10 AAAP01003863.1_30 - 0.0062 16.6 0.1 0.018 15.1 0.1 1.8 1 1 0 1 1 1 1 Zinc ribbon domain Methyltransf_23 PF13489.6 AAAP01003863.1_31 - 2.3e-08 34.0 0.0 4.9e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003863.1_31 - 1.4e-07 32.1 0.0 2.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003863.1_31 - 2.3e-06 28.2 0.0 3.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 AAAP01003863.1_31 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TehB PF03848.14 AAAP01003863.1_31 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 2 0 0 2 2 2 1 Tellurite resistance protein TehB MetW PF07021.12 AAAP01003863.1_31 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 AAAP01003863.1_31 - 0.006 16.4 0.0 0.0097 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 AAAP01003863.1_31 - 0.15 12.2 0.0 0.37 10.9 0.0 1.5 1 1 1 2 2 2 0 FtsJ-like methyltransferase CN_hydrolase PF00795.22 AAAP01003863.1_32 - 3e-46 157.9 0.1 3.4e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipocalin_2 PF08212.12 AAAP01003863.1_32 - 0.081 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like domain Glutaredoxin PF00462.24 AAAP01003863.1_33 - 4e-22 78.2 0.1 4.8e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 AAAP01003863.1_33 - 0.0014 18.7 0.1 0.0025 17.8 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 AAAP01003863.1_33 - 0.0042 17.5 0.0 0.006 17.0 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 AAAP01003863.1_33 - 0.027 14.9 0.0 0.032 14.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 AAAP01003863.1_33 - 0.038 14.1 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Pribosyltran PF00156.27 AAAP01003863.1_34 - 3.7e-06 26.5 0.1 6.9e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mu-like_Com PF10122.9 AAAP01003863.1_34 - 0.027 13.9 2.2 0.88 9.1 0.1 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com FAM76 PF16046.5 AAAP01003863.1_34 - 3.1 7.1 3.5 4.5 6.5 3.5 1.1 1 0 0 1 1 1 0 FAM76 protein DNA_RNApol_7kD PF03604.13 AAAP01003863.1_34 - 7.3 6.4 7.6 1.2 8.8 3.1 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Methyltransf_11 PF08241.12 AAAP01003863.1_35 - 2.6e-10 40.8 0.0 4.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003863.1_35 - 1.6e-07 31.3 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003863.1_35 - 1.5e-05 25.6 0.0 3.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003863.1_35 - 1.9e-05 25.3 0.0 3.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003863.1_35 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AAAP01003863.1_35 - 0.0015 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 AAAP01003863.1_35 - 0.0036 16.7 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 AAAP01003863.1_35 - 0.0079 14.8 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase SfsA PF03749.13 AAAP01003863.1_36 - 7.9e-51 171.6 0.0 1e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 AAAP01003863.1_36 - 2.1e-22 79.0 0.0 5.1e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 SfsA N-terminal OB domain Peptidase_M24 PF00557.24 AAAP01003863.1_37 - 1.7e-52 178.2 0.2 1.9e-52 178.0 0.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 adh_short_C2 PF13561.6 AAAP01003863.1_41 - 6e-48 163.4 0.0 7e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003863.1_41 - 2.2e-46 157.8 0.0 2.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAAP01003863.1_41 - 0.001 18.6 0.0 0.0063 16.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 AAAP01003863.1_41 - 0.0054 16.7 0.2 0.021 14.7 0.2 2.0 1 1 0 1 1 1 1 KR domain Glyco_trans_4_4 PF13579.6 AAAP01003863.1_41 - 0.069 13.6 2.0 0.82 10.1 0.1 2.5 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain DUF1776 PF08643.10 AAAP01003863.1_41 - 0.16 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_S49 PF01343.18 AAAP01003863.1_42 - 1.8e-73 245.6 0.0 1.7e-47 161.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 AAAP01003863.1_42 - 7.6e-06 25.9 0.0 0.0099 15.8 0.1 2.9 3 0 0 3 3 3 2 Clp protease SDH_sah PF01972.16 AAAP01003863.1_42 - 0.00072 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Herpes_ICP4_N PF03584.15 AAAP01003863.1_42 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region ECH_1 PF00378.20 AAAP01003863.1_42 - 0.2 11.0 0.6 0.83 8.9 0.1 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Rhodanese PF00581.20 AAAP01003863.1_43 - 5.2e-09 36.6 0.0 8.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain TraW_N PF12477.8 AAAP01003863.1_44 - 0.0017 18.2 1.5 0.0036 17.2 1.5 1.6 1 0 0 1 1 1 1 Sex factor F TraW protein N terminal CSD PF00313.22 AAAP01003863.1_45 - 1.1e-23 82.9 0.0 1.1e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AAAP01003863.1_45 - 0.00013 21.6 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 AAAP01003863.1_45 - 0.035 14.0 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain CBS PF00571.28 AAAP01003863.1_46 - 2.3e-09 37.6 0.0 2.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 CBS domain Sugar-bind PF04198.13 AAAP01003863.1_46 - 0.017 14.3 0.1 0.02 14.0 0.1 1.0 1 0 0 1 1 1 0 Putative sugar-binding domain DeoRC PF00455.22 AAAP01003863.1_46 - 0.1 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 DeoR C terminal sensor domain CBS PF00571.28 AAAP01003863.1_47 - 2.2e-10 40.8 0.1 2.7e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 CBS domain adh_short_C2 PF13561.6 AAAP01003863.1_48 - 1.4e-86 289.8 0.0 1.6e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003863.1_48 - 1.2e-18 67.3 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003863.1_48 - 0.0029 17.5 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Chorismate_synt PF01264.21 AAAP01003863.1_49 - 1.1e-142 474.6 0.0 1.3e-142 474.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF4863 PF16155.5 AAAP01003863.1_50 - 5.9e-45 152.8 0.0 6.7e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) RuvX PF03652.15 AAAP01003863.1_52 - 2.3e-40 138.1 0.0 2.6e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase SidE PF12252.8 AAAP01003863.1_52 - 0.17 9.4 0.0 0.21 9.1 0.0 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein LytTR PF04397.15 AAAP01003863.1_54 - 3.1e-18 65.8 0.0 4.1e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 LytTr DNA-binding domain CCG PF02754.16 AAAP01003864.1_1 - 1.5e-10 41.1 0.0 1.6e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Cysteine-rich domain FCD PF07729.12 AAAP01003864.1_2 - 1.7e-25 89.8 11.4 2.2e-25 89.5 10.7 1.5 2 0 0 2 2 2 1 FCD domain HBS1_N PF08938.10 AAAP01003864.1_2 - 0.054 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus MMPL PF03176.15 AAAP01003864.1_2 - 0.058 12.3 0.3 0.069 12.1 0.3 1.2 1 0 0 1 1 1 0 MMPL family Lactate_perm PF02652.14 AAAP01003864.1_3 - 1.8e-209 696.9 45.1 2e-209 696.7 45.1 1.0 1 0 0 1 1 1 1 L-lactate permease DUF1980 PF09323.10 AAAP01003864.1_3 - 0.75 9.7 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Peptidase_C26 PF07722.13 AAAP01003864.1_4 - 1.3e-59 201.6 0.0 1.4e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 AAAP01003864.1_4 - 1.6e-16 60.7 0.0 3e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AAAP01003864.1_4 - 0.0043 16.7 0.1 0.0066 16.1 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain S4 PF01479.25 AAAP01003864.1_5 - 2e-13 49.8 0.0 5.9e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 AAAP01003864.1_5 - 3.2e-13 50.1 0.0 2.2e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Cons_hypoth95 PF03602.15 AAAP01003864.1_6 - 2.1e-46 157.9 0.0 2.4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AAAP01003864.1_6 - 0.00016 21.3 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.15 AAAP01003864.1_6 - 0.025 14.3 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 AAAP01003864.1_6 - 0.26 10.6 0.0 0.35 10.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RmuC PF02646.16 AAAP01003864.1_7 - 3e-78 262.9 1.9 3.6e-78 262.7 0.1 1.9 2 1 0 2 2 2 1 RmuC family IFT57 PF10498.9 AAAP01003864.1_7 - 0.001 18.2 0.1 0.64 8.9 0.1 2.3 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 MLD PF11647.8 AAAP01003864.1_7 - 0.009 16.3 0.1 0.092 13.0 0.0 2.6 1 1 1 2 2 2 1 Membrane Localization Domain DUF1664 PF07889.12 AAAP01003864.1_7 - 0.0098 15.9 8.1 1 9.4 0.7 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 AAAP01003864.1_7 - 0.0098 15.9 0.1 1.2 9.2 0.1 2.8 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.12 AAAP01003864.1_7 - 0.0099 16.1 3.9 12 6.2 0.1 3.9 4 0 0 4 4 4 1 Proteins of 100 residues with WXG DUF948 PF06103.11 AAAP01003864.1_7 - 0.014 15.7 4.1 4.5 7.6 0.1 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HEPN_SAV_6107 PF18726.1 AAAP01003864.1_7 - 0.044 14.3 0.8 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 SAV_6107-like HEPN Apolipoprotein PF01442.18 AAAP01003864.1_7 - 0.27 11.1 25.4 0.043 13.7 16.0 3.1 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF16 PF01519.16 AAAP01003864.1_7 - 0.45 11.0 7.8 0.75 10.3 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 HSBP1 PF06825.12 AAAP01003864.1_7 - 0.55 10.1 3.4 11 5.9 0.7 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF745 PF05335.13 AAAP01003864.1_7 - 1.3 8.7 11.6 2 8.1 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF745) DUF2218 PF09981.9 AAAP01003864.1_7 - 1.3 9.5 4.1 6.1 7.3 0.1 3.2 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2218) PDT PF00800.18 AAAP01003864.1_8 - 5.1e-52 176.3 0.0 6.3e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase CTP_transf_3 PF02348.19 AAAP01003864.1_9 - 3.7e-41 141.5 0.0 4.6e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01003864.1_9 - 1.8e-10 41.4 0.5 2.7e-10 40.8 0.5 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain ACT_7 PF13840.6 AAAP01003864.1_9 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 ACT domain Thioredoxin PF00085.20 AAAP01003864.1_10 - 2.4e-33 114.2 0.0 2.6e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AAAP01003864.1_10 - 1.1e-08 35.3 0.0 1.9e-06 28.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAAP01003864.1_10 - 4.2e-08 33.6 0.0 4e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 AAAP01003864.1_10 - 1.5e-05 24.8 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 AAAP01003864.1_10 - 2.9e-05 23.8 0.0 0.00029 20.6 0.0 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 AAAP01003864.1_10 - 0.00027 20.8 0.0 0.00044 20.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 AAAP01003864.1_10 - 0.00063 19.9 0.0 0.0009 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like DUF836 PF05768.14 AAAP01003864.1_10 - 0.0011 19.3 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 AAAP01003864.1_10 - 0.0026 17.8 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 AAAP01003864.1_10 - 0.0034 17.2 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 AAAP01003864.1_10 - 0.0044 16.4 0.0 0.0053 16.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 AAAP01003864.1_10 - 0.18 12.1 0.0 0.33 11.2 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin Rubrerythrin PF02915.17 AAAP01003864.1_12 - 1.5e-12 48.1 0.8 8.2e-06 26.3 0.1 2.0 2 0 0 2 2 2 2 Rubrerythrin Ferritin_2 PF13668.6 AAAP01003864.1_12 - 2.1e-07 31.2 0.4 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 2 Ferritin-like domain Ferritin PF00210.24 AAAP01003864.1_12 - 0.0005 20.0 2.9 0.0011 18.9 2.9 1.6 1 1 0 1 1 1 1 Ferritin-like domain DUF2383 PF09537.10 AAAP01003864.1_12 - 0.069 13.5 0.7 0.23 11.8 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) GTA_holin_3TM PF11351.8 AAAP01003864.1_13 - 1.9e-26 93.0 2.7 2.4e-26 92.7 2.7 1.1 1 0 0 1 1 1 1 Holin of 3TMs, for gene-transfer release Phasin_2 PF09361.10 AAAP01003864.1_13 - 0.18 12.1 3.6 0.31 11.3 3.6 1.3 1 0 0 1 1 1 0 Phasin protein DUF3040 PF11239.8 AAAP01003864.1_13 - 7.4 6.9 9.3 3.5 8.0 3.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) Hemerythrin PF01814.23 AAAP01003864.1_15 - 3.6e-05 24.4 1.8 4.4e-05 24.1 1.8 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain FYDLN_acid PF09538.10 AAAP01003864.1_16 - 2.3e-27 95.8 5.2 2.8e-27 95.5 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) DZR PF12773.7 AAAP01003864.1_16 - 0.0015 18.5 2.1 0.0025 17.8 2.1 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 AAAP01003864.1_16 - 0.011 15.9 3.2 0.023 14.8 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 AAAP01003864.1_16 - 0.014 14.8 4.9 0.023 14.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AAAP01003864.1_16 - 0.019 14.8 1.2 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 AAAP01003864.1_16 - 0.033 13.9 0.1 0.033 13.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 AAAP01003864.1_16 - 0.1 12.7 0.5 0.15 12.2 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-NADH-PPase PF09297.11 AAAP01003864.1_16 - 0.1 12.2 4.6 5 6.9 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CpXC PF14353.6 AAAP01003864.1_16 - 0.16 12.0 0.0 0.16 12.0 0.0 2.2 1 1 1 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 AAAP01003864.1_16 - 0.19 11.7 8.4 1.1 9.3 1.4 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 AAAP01003864.1_16 - 0.25 11.4 1.4 0.4 10.7 1.4 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 AAAP01003864.1_16 - 1 9.0 0.1 1 9.0 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 AAAP01003864.1_16 - 2.4 7.7 9.9 0.36 10.4 5.2 2.1 2 1 0 2 2 2 0 TFIIB zinc-binding EPSP_synthase PF00275.20 AAAP01003864.1_17 - 6.3e-108 361.1 0.0 7.2e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Cytidylate_kin PF02224.18 AAAP01003864.1_18 - 6.5e-56 189.4 0.6 2.3e-55 187.6 0.6 1.7 1 1 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AAAP01003864.1_18 - 6.7e-07 29.6 0.1 1.3e-06 28.7 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 AAAP01003864.1_18 - 0.00013 22.4 0.1 0.00063 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AAAP01003864.1_18 - 0.00045 20.8 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003864.1_18 - 0.0017 18.5 0.0 0.0064 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 AAAP01003864.1_18 - 0.01 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase SKI PF01202.22 AAAP01003864.1_18 - 0.043 14.0 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase dNK PF01712.19 AAAP01003864.1_18 - 0.082 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase S1 PF00575.23 AAAP01003864.1_19 - 6.4e-99 324.4 22.8 5.8e-21 74.6 0.1 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 AAAP01003864.1_19 - 1.8e-10 41.5 5.1 0.79 10.5 0.0 6.1 2 2 4 6 6 6 3 Penicillin-binding protein OB-like domain S1_2 PF13509.6 AAAP01003864.1_19 - 2.8e-08 33.7 6.5 0.46 10.6 0.1 6.4 6 1 0 6 6 6 2 S1 domain Peptidase_A4 PF01828.17 AAAP01003864.1_19 - 0.0016 18.0 0.2 0.93 8.9 0.0 2.8 2 0 0 2 2 2 2 Peptidase A4 family SH3_2 PF07653.17 AAAP01003864.1_19 - 0.0042 16.7 2.0 1.6 8.4 0.0 4.4 5 1 0 5 5 5 1 Variant SH3 domain SH3_4 PF06347.13 AAAP01003864.1_19 - 0.09 12.6 0.0 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain PLD_C PF12357.8 AAAP01003864.1_19 - 0.092 12.7 0.1 17 5.4 0.0 2.8 3 0 0 3 3 3 0 Phospholipase D C terminal HupF_HypC PF01455.18 AAAP01003864.1_19 - 0.11 12.6 2.0 34 4.7 0.2 3.9 4 0 0 4 4 4 0 HupF/HypC family RNase_II_C_S1 PF18614.1 AAAP01003864.1_19 - 0.13 12.2 11.7 29 4.7 1.0 5.7 6 0 0 6 6 6 0 RNase II-type exonuclease C-terminal S1 domain RuvA_N PF01330.21 AAAP01003864.1_19 - 0.27 11.4 2.1 6.8 6.9 0.0 3.3 3 0 0 3 3 3 0 RuvA N terminal domain Ribosomal_L19 PF01245.20 AAAP01003864.1_19 - 0.28 11.1 4.6 23 4.9 0.9 4.3 3 1 1 4 4 4 0 Ribosomal protein L19 EXOSC1 PF10447.9 AAAP01003864.1_19 - 0.41 11.3 4.1 59 4.3 0.0 4.3 5 0 0 5 5 5 0 Exosome component EXOSC1/CSL4 CsrA PF02599.16 AAAP01003864.1_19 - 0.6 10.1 7.7 2.1 8.4 0.0 4.4 4 0 0 4 4 4 0 Global regulator protein family RNA_pol_Rbc25 PF08292.12 AAAP01003864.1_19 - 0.62 10.3 4.0 6 7.1 0.0 3.9 5 0 0 5 5 5 0 RNA polymerase III subunit Rpc25 BPL_C PF02237.17 AAAP01003864.1_19 - 1.7 8.6 11.7 8.9 6.3 0.0 5.7 6 1 1 7 7 7 0 Biotin protein ligase C terminal domain Polyketide_cyc PF03364.20 AAAP01003864.1_20 - 2.2e-24 86.1 0.0 2.7e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AAAP01003864.1_20 - 1.5e-07 31.8 0.0 1.9e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport cNMP_binding PF00027.29 AAAP01003864.1_21 - 4.6e-22 77.9 0.0 5.4e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2786 PF10979.8 AAAP01003864.1_22 - 0.0023 17.8 1.2 0.0055 16.6 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) OmpA PF00691.20 AAAP01003864.1_23 - 0.079 13.4 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 OmpA family Fez1 PF06818.15 AAAP01003864.1_23 - 0.09 13.2 0.8 0.15 12.5 0.8 1.3 1 0 0 1 1 1 0 Fez1 DUF948 PF06103.11 AAAP01003864.1_23 - 2.7 8.3 6.9 26 5.1 1.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HTH_24 PF13412.6 AAAP01003864.1_24 - 0.0041 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAAP01003864.1_24 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.12 AAAP01003864.1_24 - 0.025 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_36 PF13730.6 AAAP01003864.1_24 - 0.033 14.1 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3606 PF12244.8 AAAP01003864.1_24 - 0.063 13.2 0.3 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) HATPase_c PF02518.26 AAAP01003864.1_25 - 6.3e-24 84.6 0.1 2e-23 83.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003864.1_25 - 5.6e-13 48.7 0.2 9.6e-13 48.0 0.2 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003864.1_25 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 1 0 1 1 1 0 GHKL domain His_kinase PF06580.13 AAAP01003864.1_25 - 0.13 12.6 0.2 0.26 11.6 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase dCache_1 PF02743.18 AAAP01003864.1_26 - 1.2e-05 25.3 0.0 1.6e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Cache domain MobB PF03205.14 AAAP01003864.1_27 - 0.031 14.2 0.1 0.055 13.4 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 AAAP01003864.1_27 - 0.14 12.2 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NMN_transporter PF04973.12 AAAP01003864.1_28 - 1.7e-05 24.9 7.4 2e-05 24.6 7.4 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter Tenui_NS4 PF03300.13 AAAP01003864.1_28 - 0.16 11.3 0.2 0.19 11.1 0.2 1.1 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 Hemerythrin PF01814.23 AAAP01003864.1_30 - 1.3e-10 42.0 0.1 1.5e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LPG_synthase_TM PF03706.13 AAAP01003864.1_35 - 1.5e-33 116.6 36.6 1.9e-33 116.3 36.6 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Colicin PF01024.19 AAAP01003864.1_35 - 0.4 10.5 1.4 0.82 9.5 0.5 2.2 2 1 0 2 2 2 0 Colicin pore forming domain Glyco_trans_1_4 PF13692.6 AAAP01003864.1_36 - 1.7e-21 77.1 0.1 3.8e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003864.1_36 - 9.7e-21 74.1 0.0 1.6e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003864.1_36 - 4.1e-05 23.7 0.7 0.00019 21.5 0.7 2.2 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01003864.1_36 - 0.00012 22.4 0.0 0.00032 21.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIG-L PF02585.17 AAAP01003864.1_37 - 6e-20 72.2 0.0 9.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cep57_CLD_2 PF14197.6 AAAP01003864.1_38 - 0.013 15.6 8.6 0.029 14.4 8.5 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 cwf21 PF08312.12 AAAP01003864.1_38 - 0.02 15.1 2.9 0.02 15.1 2.9 1.8 2 0 0 2 2 2 0 cwf21 domain Nas2_N PF18265.1 AAAP01003864.1_38 - 0.041 13.8 1.8 4.4 7.3 0.0 2.5 2 1 0 2 2 2 0 Nas2 N_terminal domain HpaP PF09483.10 AAAP01003864.1_38 - 0.06 13.6 0.4 0.56 10.5 0.0 2.2 1 1 1 2 2 2 0 Type III secretion protein (HpaP) Flg_hook PF02120.16 AAAP01003864.1_38 - 0.061 13.2 1.7 0.077 12.9 0.2 1.9 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK DUF4164 PF13747.6 AAAP01003864.1_38 - 0.18 12.1 0.3 0.18 12.1 0.3 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) KfrA_N PF11740.8 AAAP01003864.1_38 - 1.3 9.7 9.1 2.1 9.1 9.1 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DNA_pol_A PF00476.20 AAAP01003864.1_40 - 1.2e-142 475.5 0.0 1.5e-142 475.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AAAP01003864.1_40 - 2.7e-57 193.1 0.0 4.3e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 AAAP01003864.1_40 - 6.2e-37 127.0 0.0 9.3e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease 5_3_exonuc PF01367.20 AAAP01003864.1_40 - 7.7e-33 113.0 0.0 1.6e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 AAAP01003864.1_40 - 0.032 14.3 0.0 0.088 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 AAAP01003864.1_40 - 0.049 14.2 0.0 0.26 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain zf-CHCC PF10276.9 AAAP01003864.1_41 - 4.7e-14 52.1 0.2 6.7e-14 51.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain ABC_tran PF00005.27 AAAP01003864.1_42 - 6.5e-32 110.9 0.0 9.2e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003864.1_42 - 7.9e-12 45.6 0.4 5.3e-06 26.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003864.1_42 - 3.3e-05 23.4 0.1 0.00084 18.8 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003864.1_42 - 0.0058 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003864.1_42 - 0.018 15.5 0.1 0.035 14.6 0.0 1.4 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003864.1_42 - 0.035 14.0 0.0 0.096 12.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase DUF4162 PF13732.6 AAAP01003864.1_42 - 0.087 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) MMR_HSR1 PF01926.23 AAAP01003864.1_42 - 0.1 12.7 0.1 0.21 11.7 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 AAAP01003864.1_42 - 0.12 12.7 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003864.1_42 - 0.12 12.1 0.1 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.19 AAAP01003864.1_42 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CLP1_P PF16575.5 AAAP01003864.1_42 - 0.18 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Hydrolase_4 PF12146.8 AAAP01003864.1_43 - 4e-66 222.7 0.0 4.8e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003864.1_43 - 4e-15 56.1 0.0 2e-13 50.6 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003864.1_43 - 1.1e-10 42.5 9.0 1.6e-10 41.9 9.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AAAP01003864.1_43 - 0.0065 16.0 0.2 0.025 14.0 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family DUF1590 PF07629.11 AAAP01003864.1_43 - 0.042 13.7 0.4 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) LRV PF01816.17 AAAP01003864.1_43 - 0.69 10.4 4.9 0.71 10.4 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat variant DUF1800 PF08811.11 AAAP01003864.1_47 - 2.4e-121 405.8 0.0 2.7e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) DUF1501 PF07394.12 AAAP01003864.1_48 - 4.6e-36 124.7 0.1 8.8e-35 120.5 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) GTP_cyclohydroI PF01227.22 AAAP01003864.1_49 - 5.1e-77 257.3 0.0 5.9e-77 257.1 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 AAAP01003864.1_49 - 0.00069 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein EIF_2_alpha PF07541.12 AAAP01003864.1_49 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit DUF525 PF04379.14 AAAP01003864.1_50 - 3.5e-36 123.3 0.0 4.2e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 ApaG domain Cys_Met_Meta_PP PF01053.20 AAAP01003864.1_51 - 1.5e-129 431.9 0.0 1.6e-129 431.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AAAP01003864.1_51 - 1.4e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAAP01003864.1_51 - 2.7e-07 30.2 0.1 5.4e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAAP01003864.1_51 - 1.6e-06 27.4 0.0 2.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 AAAP01003864.1_51 - 2.6e-05 23.3 0.0 3.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 AAAP01003864.1_51 - 0.1 11.1 0.1 0.47 8.9 0.0 1.8 2 0 0 2 2 2 0 Methionine gamma-lyase adh_short_C2 PF13561.6 AAAP01003864.1_52 - 1.4e-82 276.8 0.0 1.6e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003864.1_52 - 1.2e-22 80.3 0.0 1.6e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 AAAP01003864.1_52 - 0.013 14.8 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region PNP_UDP_1 PF01048.20 AAAP01003864.1_53 - 0.19 10.9 0.2 0.22 10.7 0.2 1.0 1 0 0 1 1 1 0 Phosphorylase superfamily Peptidase_S24 PF00717.23 AAAP01003864.1_54 - 2.6e-17 62.5 0.0 4.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_31 PF13560.6 AAAP01003864.1_54 - 0.012 16.0 0.9 0.02 15.2 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003864.1_54 - 0.017 15.5 0.0 0.04 14.4 0.0 1.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MarR_2 PF12802.7 AAAP01003864.1_54 - 0.027 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AAAP01003864.1_54 - 0.075 12.8 0.4 0.53 10.1 0.2 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain Molydop_binding PF01568.21 AAAP01003864.1_54 - 0.086 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF4726 PF15855.5 AAAP01003864.1_57 - 0.015 15.5 0.5 0.025 14.8 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) Head-tail_con PF12236.8 AAAP01003864.1_58 - 3.4e-161 536.9 0.0 4e-161 536.7 0.0 1.0 1 0 0 1 1 1 1 Bacteriophage head to tail connecting protein Phage_integrase PF00589.22 AAAP01003865.1_1 - 2.3e-09 37.3 0.0 5.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAAP01003865.1_1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FTSW_RODA_SPOVE PF01098.19 AAAP01003865.1_2 - 2.6e-100 335.9 27.7 3.3e-100 335.6 27.7 1.0 1 0 0 1 1 1 1 Cell cycle protein LapA_dom PF06305.11 AAAP01003865.1_2 - 0.7 9.8 0.0 0.7 9.8 0.0 3.6 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Transpeptidase PF00905.22 AAAP01003865.1_3 - 9.3e-14 51.3 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Transpeptidase PF00905.22 AAAP01003865.1_4 - 1.6e-42 145.8 0.0 2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AAAP01003865.1_4 - 3.7e-38 131.7 0.0 5.8e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Peptidase_S13 PF02113.15 AAAP01003865.1_4 - 0.21 10.3 0.3 0.92 8.2 0.0 2.0 3 0 0 3 3 3 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family MreD PF04093.12 AAAP01003865.1_5 - 1.6e-10 41.3 13.1 2.3e-10 40.8 12.9 1.3 1 1 0 1 1 1 1 rod shape-determining protein MreD MreC PF04085.14 AAAP01003865.1_6 - 7.5e-31 107.1 0.2 1.1e-30 106.5 0.2 1.3 1 0 0 1 1 1 1 rod shape-determining protein MreC PRKG1_interact PF15898.5 AAAP01003865.1_6 - 0.0022 18.9 0.2 0.0046 17.8 0.2 1.5 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain DHR10 PF18595.1 AAAP01003865.1_6 - 0.033 14.2 0.2 0.05 13.7 0.2 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain XRCC4 PF06632.12 AAAP01003865.1_6 - 0.045 12.6 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ZapB PF06005.12 AAAP01003865.1_6 - 0.14 12.6 0.9 0.26 11.7 0.9 1.4 1 0 0 1 1 1 0 Cell division protein ZapB RnfC_N PF13375.6 AAAP01003865.1_6 - 0.26 11.3 1.3 19 5.3 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain MreB_Mbl PF06723.13 AAAP01003865.1_7 - 5.1e-153 508.6 7.3 5.8e-153 508.5 7.3 1.0 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 AAAP01003865.1_7 - 2.3e-13 49.5 0.0 2.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 Actin FtsA PF14450.6 AAAP01003865.1_7 - 2e-12 47.5 1.9 3.4e-12 46.7 0.2 2.1 2 1 0 2 2 2 1 Cell division protein FtsA HSP70 PF00012.20 AAAP01003865.1_7 - 6.1e-12 44.5 0.5 1.1e-11 43.7 0.1 1.8 2 1 0 2 2 2 1 Hsp70 protein PilM_2 PF11104.8 AAAP01003865.1_7 - 2.9e-08 33.1 0.0 0.0026 16.8 0.0 3.0 3 0 0 3 3 3 2 Type IV pilus assembly protein PilM; EutA PF06277.11 AAAP01003865.1_7 - 0.0018 17.2 0.3 0.0018 17.2 0.3 1.8 3 0 0 3 3 3 1 Ethanolamine utilisation protein EutA U79_P34 PF03064.16 AAAP01003865.1_7 - 0.0062 15.9 0.2 1.8 7.9 0.0 2.1 2 0 0 2 2 2 2 HSV U79 / HCMV P34 HMGL-like PF00682.19 AAAP01003865.1_8 - 2.1e-98 329.1 0.4 3e-98 328.6 0.4 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AAAP01003865.1_8 - 3.2e-28 98.3 0.1 7.5e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4351 PF14261.6 AAAP01003865.1_9 - 0.013 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Trypan_PARP PF05887.11 AAAP01003865.1_9 - 0.4 10.6 5.2 0.75 9.8 5.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IlvN PF07991.12 AAAP01003865.1_10 - 2.3e-71 238.7 1.8 3.2e-71 238.2 1.8 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AAAP01003865.1_10 - 1.6e-66 223.0 0.1 2.2e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.21 AAAP01003865.1_10 - 8.4e-06 25.9 0.1 1.5e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAAP01003865.1_10 - 2.6e-05 23.7 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAAP01003865.1_10 - 0.00013 22.1 0.2 0.00025 21.3 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01003865.1_10 - 0.00018 22.0 0.1 0.00034 21.1 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.19 AAAP01003865.1_10 - 0.017 13.8 0.2 0.033 12.9 0.2 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Shikimate_DH PF01488.20 AAAP01003865.1_10 - 0.024 14.7 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 AAAP01003865.1_10 - 0.027 15.3 0.0 0.049 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 AAAP01003865.1_10 - 0.033 14.6 0.1 0.099 13.1 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1103 PF06513.11 AAAP01003865.1_10 - 0.038 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) NT5C PF06941.12 AAAP01003865.1_10 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) GARS_N PF02844.15 AAAP01003865.1_10 - 0.11 13.3 0.1 0.45 11.3 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain ThiF PF00899.21 AAAP01003865.1_10 - 0.12 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family ALS_ss_C PF10369.9 AAAP01003865.1_11 - 6.5e-26 90.4 1.4 1.1e-25 89.6 0.3 1.9 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 AAAP01003865.1_11 - 1.9e-10 40.4 0.1 4.1e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AAAP01003865.1_11 - 5.8e-10 38.8 2.0 6.3e-10 38.6 0.3 1.9 2 1 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AAAP01003865.1_11 - 0.0038 17.8 0.3 0.0083 16.7 0.3 1.6 1 1 0 1 1 1 1 ACT domain Glycoprotein PF03409.15 AAAP01003865.1_11 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein TPP_enzyme_C PF02775.21 AAAP01003865.1_12 - 7.7e-49 165.4 0.1 8.7e-48 162.0 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AAAP01003865.1_12 - 8.8e-46 155.0 0.0 1.8e-45 154.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 AAAP01003865.1_12 - 3.7e-30 104.8 0.1 3.7e-29 101.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CO_dh PF02552.16 AAAP01003865.1_12 - 0.08 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPP_enzyme_N PF02776.18 AAAP01003865.1_13 - 1.2e-22 80.4 0.1 1.3e-22 80.3 0.1 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PrpR_N PF06506.11 AAAP01003865.1_13 - 0.065 12.8 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Propionate catabolism activator IPPT PF01715.17 AAAP01003865.1_14 - 9.9e-57 192.4 0.0 1.2e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AAAP01003865.1_14 - 5.5e-05 22.7 0.0 0.00019 20.9 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 AAAP01003865.1_14 - 0.0013 18.9 0.1 0.013 15.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain Hydin_ADK PF17213.3 AAAP01003865.1_14 - 0.0025 18.1 0.8 0.032 14.5 0.2 2.3 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 AAAP01003865.1_14 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 AAAP01003865.1_14 - 0.016 15.6 0.1 0.067 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 AAAP01003865.1_14 - 0.016 14.4 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 AAAP01003865.1_14 - 0.027 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TPR_2 PF07719.17 AAAP01003865.1_18 - 0.0051 16.8 2.5 7.9 6.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003865.1_18 - 0.036 14.7 9.5 0.42 11.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003865.1_18 - 0.084 13.5 23.7 0.41 11.3 0.1 5.3 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003865.1_18 - 0.34 11.5 13.9 4.2 8.0 0.2 5.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003865.1_18 - 7.3 7.7 19.8 1 10.4 0.0 6.7 6 2 2 8 8 8 0 Tetratricopeptide repeat CheZ PF04344.13 AAAP01003865.1_19 - 8.1e-17 61.8 1.3 3.2e-11 43.5 0.0 2.6 2 1 1 3 3 3 2 Chemotaxis phosphatase, CheZ SH3BP5 PF05276.14 AAAP01003865.1_19 - 0.053 13.3 0.0 0.096 12.5 0.0 1.4 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) MnmE_helical PF12631.7 AAAP01003865.1_19 - 0.078 13.1 1.7 0.2 11.8 0.4 2.1 1 1 1 2 2 2 0 MnmE helical domain ABC_tran_CTD PF16326.5 AAAP01003865.1_19 - 0.079 13.2 1.5 4.2 7.7 0.8 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF1018 PF06252.12 AAAP01003865.1_19 - 0.09 13.8 0.0 0.15 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) DUF1664 PF07889.12 AAAP01003865.1_19 - 0.14 12.2 0.6 1.3 9.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Response_reg PF00072.24 AAAP01003865.1_20 - 1.3e-28 99.4 0.1 1.5e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Secretin_N PF03958.17 AAAP01003865.1_20 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain ApoB100_C PF12491.8 AAAP01003865.1_20 - 0.15 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal MgtE_N PF03448.17 AAAP01003865.1_21 - 9.4e-07 29.4 1.5 9.4e-07 29.4 1.5 2.0 2 0 0 2 2 2 1 MgtE intracellular N domain FliG_M PF14841.6 AAAP01003865.1_21 - 0.0039 17.4 5.0 0.12 12.6 0.1 3.0 2 2 1 3 3 3 2 FliG middle domain ECM11 PF15463.6 AAAP01003865.1_21 - 0.014 16.0 1.3 0.014 16.0 1.3 2.5 2 1 0 2 2 2 0 Extracellular mutant protein 11 FliG_N PF14842.6 AAAP01003865.1_21 - 0.054 14.0 4.2 0.6 10.7 0.2 3.2 2 1 1 3 3 3 0 FliG N-terminal domain DUF3552 PF12072.8 AAAP01003865.1_21 - 0.095 12.1 11.3 0.15 11.5 11.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) PPR_3 PF13812.6 AAAP01003865.1_21 - 0.1 12.7 1.4 0.26 11.4 0.2 2.2 1 1 1 2 2 2 0 Pentatricopeptide repeat domain Jnk-SapK_ap_N PF09744.9 AAAP01003865.1_22 - 0.0018 18.5 0.9 0.0029 17.8 0.1 1.6 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 AAAP01003865.1_22 - 0.0091 13.6 1.4 0.012 13.1 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 AAAP01003865.1_22 - 0.019 13.9 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.11 AAAP01003865.1_22 - 0.036 13.0 1.3 0.053 12.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2570 PF10828.8 AAAP01003865.1_22 - 0.04 13.7 0.2 0.077 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DegS PF05384.11 AAAP01003865.1_22 - 0.24 10.9 3.9 2 7.9 1.6 2.2 1 1 1 2 2 2 0 Sensor protein DegS FlgN PF05130.12 AAAP01003865.1_22 - 0.65 10.5 6.3 0.074 13.6 1.4 1.7 2 0 0 2 2 2 0 FlgN protein DUF4200 PF13863.6 AAAP01003865.1_22 - 2.9 8.3 7.1 0.25 11.7 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 AAAP01003865.1_22 - 3.4 7.7 11.2 0.076 13.1 3.0 2.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FliM PF02154.15 AAAP01003865.1_23 - 1.1e-65 221.1 0.1 1.6e-65 220.6 0.1 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AAAP01003865.1_23 - 2.6e-18 65.8 0.0 1.6e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Type III flagellar switch regulator (C-ring) FliN C-term FliL PF03748.14 AAAP01003865.1_24 - 4.6e-19 68.9 0.8 8.3e-19 68.1 0.8 1.4 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL Flg_bbr_C PF06429.13 AAAP01003865.1_25 - 2.9e-14 52.9 1.4 8.5e-14 51.5 1.4 1.8 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01003865.1_25 - 9.2e-08 31.9 0.4 1.9e-07 30.9 0.4 1.6 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAAP01003865.1_26 - 1.7e-27 95.3 0.3 6e-27 93.6 0.3 2.0 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01003865.1_26 - 1.3e-09 37.8 8.2 3e-09 36.6 8.2 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein Nuc_deoxyrib_tr PF05014.15 AAAP01003865.1_26 - 0.11 12.5 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase ChapFlgA PF13144.6 AAAP01003865.1_27 - 8e-32 109.9 3.6 8e-32 109.9 3.6 1.9 2 0 0 2 2 2 1 Chaperone for flagella basal body P-ring formation SAF PF08666.12 AAAP01003865.1_27 - 0.00028 21.4 1.2 0.00099 19.7 0.1 2.5 3 0 0 3 3 3 1 SAF domain ChapFlgA_N PF17656.1 AAAP01003865.1_27 - 0.0036 17.4 0.1 0.0096 16.1 0.0 1.7 2 0 0 2 2 2 1 FlgA N-terminal domain FlgH PF02107.16 AAAP01003865.1_28 - 6.9e-53 178.7 0.8 8.4e-53 178.4 0.8 1.1 1 0 0 1 1 1 1 Flagellar L-ring protein Trypsin_2 PF13365.6 AAAP01003865.1_29 - 1.6e-32 113.5 0.2 2.6e-32 112.8 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAAP01003865.1_29 - 3.2e-29 101.1 0.2 1.5e-16 60.5 0.2 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 AAAP01003865.1_29 - 2.5e-22 78.4 1.3 4.8e-11 42.3 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AAAP01003865.1_29 - 6.2e-19 68.1 0.3 4.7e-09 36.5 0.0 2.9 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AAAP01003865.1_29 - 4.4e-14 52.8 0.0 1e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 AAAP01003865.1_29 - 0.02 14.8 0.2 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 AAAP01003865.1_29 - 0.035 12.7 0.2 0.19 10.3 0.2 1.8 2 0 0 2 2 2 0 Peptidase S46 GRASP55_65 PF04495.14 AAAP01003865.1_29 - 0.083 13.2 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain DUF2065 PF09838.9 AAAP01003865.1_30 - 4.6e-18 65.0 12.4 5.2e-18 64.8 12.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2065) Tetraspanin PF00335.20 AAAP01003865.1_30 - 0.21 11.3 1.5 0.24 11.1 1.5 1.0 1 0 0 1 1 1 0 Tetraspanin family Band_7 PF01145.25 AAAP01003865.1_31 - 9.9e-30 103.8 3.2 9.9e-30 103.8 3.2 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AAAP01003865.1_31 - 0.0077 16.0 0.3 0.014 15.1 0.3 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family MgtE_N PF03448.17 AAAP01003865.1_31 - 0.024 15.2 1.4 0.06 13.9 1.4 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain DUF3323 PF11796.8 AAAP01003865.1_31 - 0.058 13.3 5.1 0.084 12.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DNMT1-RFD PF12047.8 AAAP01003865.1_31 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain FXMR_C2 PF16098.5 AAAP01003865.1_31 - 0.14 12.7 1.6 0.29 11.6 1.6 1.4 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 Band_7 PF01145.25 AAAP01003865.1_32 - 1.3e-28 100.2 2.8 1.5e-28 100.0 0.6 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family FTCD_C PF04961.12 AAAP01003865.1_32 - 0.00075 19.3 0.4 0.00075 19.3 0.4 2.3 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase HflK_N PF12221.8 AAAP01003865.1_32 - 0.0014 18.6 35.8 0.8 9.8 35.8 2.5 1 1 0 1 1 1 1 Bacterial membrane protein N terminal SIKE PF05769.11 AAAP01003865.1_32 - 0.035 14.0 0.3 0.078 12.9 0.0 1.6 2 0 0 2 2 2 0 SIKE family DivIVA PF05103.13 AAAP01003865.1_32 - 2 8.5 5.4 4.3 7.4 0.4 2.2 1 1 1 2 2 2 0 DivIVA protein ParA PF10609.9 AAAP01003865.1_33 - 3.1e-105 351.0 0.3 4.1e-105 350.7 0.3 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AAAP01003865.1_33 - 2.6e-16 59.5 0.8 6.9e-16 58.2 0.4 1.9 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AAAP01003865.1_33 - 6.7e-14 52.0 0.0 1.3e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003865.1_33 - 6.1e-10 39.3 0.2 2.9e-08 33.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 AAAP01003865.1_33 - 1.9e-08 34.1 0.1 7.1e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 AAAP01003865.1_33 - 2.7e-08 33.4 0.0 5.8e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AAAP01003865.1_33 - 1.2e-05 24.7 2.7 0.00037 19.8 0.9 2.7 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AAAP01003865.1_33 - 0.0026 17.1 0.3 0.0051 16.1 0.3 1.4 1 0 0 1 1 1 1 VirC1 protein SRP54 PF00448.22 AAAP01003865.1_33 - 0.013 15.1 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 AAAP01003865.1_33 - 0.041 12.8 0.2 0.07 12.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 AAAP01003865.1_33 - 0.07 12.7 0.4 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AAAP01003865.1_33 - 0.081 12.8 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase Pirin_C PF05726.13 AAAP01003865.1_33 - 0.1 13.0 0.0 16 5.9 0.0 2.4 2 0 0 2 2 2 0 Pirin C-terminal cupin domain AAA_26 PF13500.6 AAAP01003865.1_33 - 0.12 12.1 1.5 22 4.8 0.3 3.1 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.15 AAAP01003865.1_33 - 0.15 11.9 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 NTPase A2L_zn_ribbon PF08792.10 AAAP01003865.1_33 - 0.17 11.6 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain FTHFS PF01268.19 AAAP01003865.1_33 - 0.22 9.7 1.0 0.31 9.2 1.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase BRK PF07533.16 AAAP01003865.1_34 - 0.23 11.1 0.8 19 5.0 0.0 3.0 3 0 0 3 3 3 0 BRK domain MlaC PF05494.12 AAAP01003865.1_35 - 8.4e-35 120.0 0.0 9.7e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 MlaC protein TrbC PF04956.13 AAAP01003865.1_35 - 0.02 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF3828 PF12883.7 AAAP01003865.1_35 - 0.065 13.6 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Glyco_transf_21 PF13506.6 AAAP01003865.1_36 - 1.6e-48 164.4 0.1 2.6e-48 163.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 AAAP01003865.1_36 - 8.4e-29 101.1 0.0 1.1e-28 100.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AAAP01003865.1_36 - 1.4e-13 51.2 0.2 2.6e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 AAAP01003865.1_36 - 7.9e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Radical_SAM PF04055.21 AAAP01003865.1_37 - 1.5e-15 58.0 0.1 2.6e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003865.1_37 - 0.00035 20.6 0.2 0.016 15.2 0.1 2.7 2 1 0 2 2 2 1 B12 binding domain MgsA_C PF12002.8 AAAP01003865.1_38 - 1.1e-71 240.1 0.1 1.7e-71 239.6 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AAAP01003865.1_38 - 7.2e-18 64.7 0.1 1.5e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 AAAP01003865.1_38 - 1.3e-14 54.8 0.0 2.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAAP01003865.1_38 - 5.1e-11 42.6 0.0 9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AAAP01003865.1_38 - 4.8e-06 26.6 0.1 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AAAP01003865.1_38 - 5.1e-06 27.0 1.0 0.00043 20.7 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 AAAP01003865.1_38 - 4.5e-05 23.2 0.0 0.059 13.1 0.0 2.3 1 1 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 AAAP01003865.1_38 - 4.5e-05 24.0 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AAAP01003865.1_38 - 0.00014 22.1 0.1 0.019 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 AAAP01003865.1_38 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 AAAP01003865.1_38 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AAAP01003865.1_38 - 0.00027 20.4 0.2 0.017 14.5 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AAAP01003865.1_38 - 0.00091 19.0 0.0 1.2 8.8 0.0 2.5 1 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 AAAP01003865.1_38 - 0.0066 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 AAAP01003865.1_38 - 0.0069 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AAAP01003865.1_38 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AAAP01003865.1_38 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 AAAP01003865.1_38 - 0.012 15.8 0.0 0.028 14.5 0.0 1.6 2 0 0 2 2 1 0 Shikimate kinase RNA_helicase PF00910.22 AAAP01003865.1_38 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 AAAP01003865.1_38 - 0.017 15.2 0.0 1.6 8.7 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 AAAP01003865.1_38 - 0.021 15.3 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AAAP01003865.1_38 - 0.022 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 AAAP01003865.1_38 - 0.023 14.6 0.0 0.088 12.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AAAP01003865.1_38 - 0.029 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01003865.1_38 - 0.029 14.7 0.1 3.9 7.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 AAAP01003865.1_38 - 0.03 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 AAAP01003865.1_38 - 0.032 13.4 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 AAAP01003865.1_38 - 0.056 13.0 1.6 0.1 12.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAAP01003865.1_38 - 0.068 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 AAAP01003865.1_38 - 0.085 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 AAAP01003865.1_38 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Parvo_NS1 PF01057.17 AAAP01003865.1_38 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 AAAP01003865.1_38 - 0.2 11.6 0.2 0.54 10.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Trypsin_2 PF13365.6 AAAP01003865.1_39 - 2.2e-33 116.3 3.7 3.9e-33 115.5 3.7 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AAAP01003865.1_39 - 6.6e-21 74.4 0.4 4e-13 49.5 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 AAAP01003865.1_39 - 6.7e-19 67.5 4.1 6e-08 32.4 0.0 3.9 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AAAP01003865.1_39 - 4e-16 59.5 0.3 7.5e-16 58.6 0.3 1.4 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 AAAP01003865.1_39 - 8.1e-16 58.1 0.8 2e-06 28.1 0.0 3.8 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 AAAP01003865.1_39 - 9e-06 25.6 0.8 0.0025 17.7 0.0 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 AAAP01003865.1_39 - 0.0017 17.1 1.0 0.66 8.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 ThiS PF02597.20 AAAP01003865.1_39 - 0.013 16.1 0.1 3.6 8.3 0.0 3.4 3 0 0 3 3 3 0 ThiS family DUF4148 PF13663.6 AAAP01003865.1_39 - 2.8 8.2 8.7 1 9.6 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF1015 PF06245.11 AAAP01003865.1_40 - 4.2e-128 427.6 0.0 4.7e-128 427.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) ParBc_2 PF08857.11 AAAP01003865.1_40 - 0.076 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative ParB-like nuclease HAD PF12710.7 AAAP01003865.1_41 - 1.8e-17 64.3 0.3 6.8e-17 62.5 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003865.1_41 - 6.2e-10 39.7 0.7 1.1e-09 38.9 0.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003865.1_41 - 2.8e-08 33.8 0.0 8e-08 32.3 0.0 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AAAP01003865.1_41 - 0.0029 17.2 0.2 0.47 9.9 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Sigma70_r2 PF04542.14 AAAP01003865.1_42 - 4.2e-14 52.1 1.4 8.5e-14 51.1 1.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAAP01003865.1_42 - 4.5e-12 45.5 2.4 8.3e-12 44.6 0.2 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003865.1_42 - 1.1e-07 31.2 0.8 1.6e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 AAAP01003865.1_42 - 0.0024 18.5 0.0 0.005 17.5 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain CMD PF02627.20 AAAP01003865.1_43 - 8e-15 54.7 0.4 1.4e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family HlyD_3 PF13437.6 AAAP01003865.1_44 - 1.5e-14 54.6 0.5 1.5e-14 54.6 0.5 3.0 3 2 1 4 4 4 1 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003865.1_44 - 7.6e-10 38.4 2.6 1.4e-07 30.9 0.3 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AAAP01003865.1_44 - 4e-06 26.6 0.0 9.7e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003865.1_44 - 2.3e-05 24.1 0.8 0.012 15.4 0.0 3.8 3 2 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003865.1_44 - 0.0057 16.5 1.6 0.1 12.4 0.2 2.9 2 1 0 2 2 2 1 Biotin-requiring enzyme FH2 PF02181.23 AAAP01003865.1_44 - 0.006 15.7 2.8 0.0092 15.1 2.8 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain OEP PF02321.18 AAAP01003865.1_44 - 0.015 15.1 7.3 0.015 15.1 7.3 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein FoP_duplication PF13865.6 AAAP01003865.1_44 - 0.59 10.7 2.3 1.9 9.1 0.4 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 TPR_MLP1_2 PF07926.12 AAAP01003865.1_44 - 1.4 9.0 13.0 4 7.5 7.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 AAAP01003865.1_44 - 4.8 5.7 8.9 0.91 8.1 1.3 2.1 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AAAP01003865.1_45 - 1.1e-31 110.1 0.0 2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AAAP01003865.1_45 - 3.3e-29 102.4 3.8 4.1e-29 102.1 3.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 AAAP01003865.1_45 - 9.5e-15 55.2 0.2 2.8e-07 30.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAAP01003865.1_45 - 1.2e-07 31.8 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AAAP01003865.1_45 - 9.1e-07 28.5 0.1 0.027 13.9 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003865.1_45 - 0.00044 19.9 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003865.1_45 - 0.00058 20.4 0.0 0.00092 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003865.1_45 - 0.015 15.6 0.3 0.058 13.8 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 AAAP01003865.1_45 - 0.033 13.9 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003865.1_45 - 0.037 14.3 0.5 0.23 11.8 0.5 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 AAAP01003865.1_45 - 0.051 12.6 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3584 PF12128.8 AAAP01003865.1_45 - 0.058 10.9 0.0 0.08 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DLIC PF05783.11 AAAP01003865.1_45 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 AAAP01003865.1_45 - 0.12 12.8 0.0 29 5.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AAAP01003865.1_45 - 0.15 12.0 0.2 0.49 10.3 0.2 1.8 1 0 0 1 1 1 0 NACHT domain ABC_ATPase PF09818.9 AAAP01003865.1_45 - 0.23 10.2 0.1 0.59 8.9 0.2 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class HAMP PF00672.25 AAAP01003865.1_46 - 2.2e-08 34.4 1.4 4e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 HAMP domain 4HB_MCP_1 PF12729.7 AAAP01003865.1_46 - 3.9e-06 26.5 0.0 1.3e-05 24.8 0.0 2.0 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction CHASE3 PF05227.13 AAAP01003865.1_46 - 0.046 13.6 0.1 0.046 13.6 0.1 2.2 2 1 0 2 2 2 0 CHASE3 domain DUF4254 PF14063.6 AAAP01003866.1_2 - 0.00018 21.4 0.2 0.18 11.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4254) YwqJ-deaminase PF14431.6 AAAP01003866.1_2 - 0.027 14.7 0.1 0.033 14.4 0.1 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase HAD_2 PF13419.6 AAAP01003866.1_2 - 0.065 13.3 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FmdE PF02663.14 AAAP01003866.1_3 - 0.00069 19.7 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CreA PF05981.12 AAAP01003866.1_4 - 3.2e-56 188.9 0.1 3.8e-56 188.7 0.1 1.0 1 0 0 1 1 1 1 CreA protein Pyrophosphatase PF00719.19 AAAP01003866.1_7 - 3.1e-52 176.6 0.0 3.5e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase AlaDh_PNT_C PF01262.21 AAAP01003866.1_8 - 2.1e-80 269.0 3.9 2.8e-80 268.7 3.9 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AAAP01003866.1_8 - 1.5e-47 161.3 0.0 2.5e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.20 AAAP01003866.1_8 - 1.4e-06 28.4 0.1 2.6e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01003866.1_8 - 9.7e-05 21.8 0.1 0.00021 20.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 AAAP01003866.1_8 - 0.0013 18.1 0.8 0.0023 17.3 0.8 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 AAAP01003866.1_8 - 0.0017 18.6 1.0 0.022 14.9 0.4 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 AAAP01003866.1_8 - 0.0046 16.2 1.1 0.011 15.0 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003866.1_8 - 0.0047 17.5 0.5 0.011 16.2 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 AAAP01003866.1_8 - 0.0066 16.7 0.4 0.024 14.9 0.2 2.0 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AAAP01003866.1_8 - 0.017 15.6 0.2 0.034 14.6 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 AAAP01003866.1_8 - 0.022 14.7 0.6 0.044 13.7 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 AAAP01003866.1_9 - 4.6e-21 75.1 42.9 4.6e-21 75.1 42.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 AAAP01003866.1_9 - 4.7e-14 51.8 4.4 1.7e-12 46.6 1.3 2.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Lyase_1 PF00206.20 AAAP01003866.1_10 - 1.7e-81 274.0 0.0 2.6e-81 273.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AAAP01003866.1_10 - 1.7e-20 73.5 0.0 4.7e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal LPAM_2 PF13627.6 AAAP01003866.1_11 - 1.2e-06 28.2 0.1 1.5e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site Orn_Arg_deC_N PF02784.16 AAAP01003866.1_12 - 7.7e-59 199.0 0.0 1.3e-58 198.3 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AAAP01003866.1_12 - 1.9e-27 95.3 0.0 2.3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AAAP01003866.1_12 - 6.9e-10 38.9 0.1 1.2e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4175 PF13779.6 AAAP01003866.1_13 - 3.2e-196 653.9 48.0 3.7e-196 653.7 48.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) SesA PF17107.5 AAAP01003866.1_13 - 0.0036 17.5 0.8 0.32 11.2 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AP_endonuc_2 PF01261.24 AAAP01003866.1_13 - 0.016 14.6 0.7 0.045 13.2 0.7 1.8 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel YfdX PF10938.8 AAAP01003866.1_13 - 0.041 13.8 2.7 0.3 11.0 0.0 2.7 2 0 0 2 2 2 0 YfdX protein 7TMR-HDED PF07697.11 AAAP01003866.1_13 - 0.061 13.4 5.2 2 8.5 5.3 2.2 1 1 0 1 1 1 0 7TM-HD extracellular GrpE PF01025.19 AAAP01003866.1_13 - 0.16 11.6 0.1 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 GrpE WXG100 PF06013.12 AAAP01003866.1_13 - 0.7 10.2 10.8 0.48 10.7 4.7 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG RsbRD_N PF14361.6 AAAP01003866.1_13 - 1.4 9.7 5.4 9 7.1 0.1 3.8 2 2 1 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF4795 PF16043.5 AAAP01003866.1_13 - 2.3 7.8 7.9 54 3.3 7.9 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3426 PF11906.8 AAAP01003866.1_14 - 1.9e-19 70.3 0.2 3.9e-19 69.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3426) zinc_ribbon_4 PF13717.6 AAAP01003866.1_14 - 3.1e-14 52.6 0.3 5.3e-14 51.9 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 AAAP01003866.1_14 - 8.4e-10 38.2 0.5 1.5e-09 37.5 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain EAL PF00563.20 AAAP01003866.1_15 - 3.8e-72 242.7 0.0 6.3e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003866.1_15 - 2.6e-48 163.8 0.0 4.5e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003866.1_15 - 1.8e-23 82.7 0.0 1.3e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AAAP01003866.1_15 - 6.9e-20 70.6 0.3 6.5e-10 38.8 0.1 3.6 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 AAAP01003866.1_15 - 2.3e-17 63.0 0.1 2.5e-09 37.1 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01003866.1_15 - 5.5e-13 49.1 2.5 2.4e-07 31.0 0.2 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAAP01003866.1_15 - 1.9e-11 44.1 0.0 4.2e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.7 AAAP01003866.1_15 - 0.025 14.8 0.1 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 PAS fold GGDEF_2 PF17853.1 AAAP01003866.1_15 - 0.034 14.4 1.2 0.24 11.6 0.0 2.8 2 2 1 3 3 3 0 GGDEF-like domain DapB_C PF05173.14 AAAP01003866.1_16 - 7.1e-45 151.9 0.0 1.1e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 AAAP01003866.1_16 - 3.9e-35 120.7 0.1 7e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NDUF_B12 PF08122.12 AAAP01003866.1_17 - 0.11 12.5 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family GrpE PF01025.19 AAAP01003866.1_18 - 4e-51 173.0 1.0 4.7e-51 172.8 1.0 1.1 1 0 0 1 1 1 1 GrpE DUF5098 PF17023.5 AAAP01003866.1_18 - 0.015 14.3 0.1 0.019 13.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) Pil1 PF13805.6 AAAP01003866.1_18 - 0.052 13.0 2.8 0.075 12.5 2.6 1.3 1 1 0 1 1 1 0 Eisosome component PIL1 eIF3_subunit PF08597.10 AAAP01003866.1_18 - 0.11 12.4 7.8 0.14 12.1 7.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit V_ATPase_I PF01496.19 AAAP01003866.1_18 - 0.24 9.3 0.2 0.29 9.0 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 AAAP01003866.1_18 - 0.33 9.5 2.5 0.38 9.3 2.5 1.1 1 0 0 1 1 1 0 Macoilin family Golgin_A5 PF09787.9 AAAP01003866.1_18 - 0.58 9.6 4.7 0.83 9.1 4.7 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 DivIC PF04977.15 AAAP01003866.1_18 - 0.95 9.3 4.2 4.3 7.2 4.2 2.0 1 1 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 AAAP01003866.1_18 - 2 7.7 7.2 2.3 7.5 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HalX PF08663.10 AAAP01003866.1_18 - 7.4 7.0 9.9 73 3.8 0.1 3.1 2 1 0 2 2 2 0 HalX domain HrcA PF01628.21 AAAP01003866.1_19 - 3.2e-54 184.1 0.0 4.4e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 HrcA protein C terminal domain HrcA_DNA-bdg PF03444.15 AAAP01003866.1_19 - 0.00095 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding LexA_DNA_bind PF01726.16 AAAP01003866.1_19 - 0.023 14.5 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 LexA DNA binding domain DUF2111 PF09884.9 AAAP01003866.1_19 - 0.045 13.8 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) HTH_11 PF08279.12 AAAP01003866.1_19 - 0.059 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain RNase_PH PF01138.21 AAAP01003866.1_20 - 1.3e-23 83.9 0.0 2.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AAAP01003866.1_20 - 2.6e-09 37.0 0.0 5.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ham1p_like PF01725.16 AAAP01003866.1_21 - 4.9e-62 209.2 0.0 5.5e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Radical_SAM PF04055.21 AAAP01003866.1_22 - 1.3e-18 67.9 0.0 1.9e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AAAP01003866.1_22 - 1.1e-12 47.8 2.0 3.1e-12 46.4 2.0 1.8 1 0 0 1 1 1 1 HemN C-terminal domain Fer4_14 PF13394.6 AAAP01003866.1_22 - 0.027 14.6 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Peripla_BP_6 PF13458.6 AAAP01003866.1_23 - 4.1e-34 118.8 12.3 3.1e-33 115.9 12.3 1.9 1 1 0 1 1 1 1 Periplasmic binding protein LppC PF04348.13 AAAP01003866.1_23 - 2.1e-14 53.2 0.5 2.9e-14 52.8 0.5 1.1 1 0 0 1 1 1 1 LppC putative lipoprotein ANF_receptor PF01094.28 AAAP01003866.1_23 - 6.8e-09 35.3 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAAP01003866.1_23 - 0.0014 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_4 PF13407.6 AAAP01003866.1_23 - 0.1 12.1 1.2 0.32 10.5 1.2 1.7 1 1 0 1 1 1 0 Periplasmic binding protein domain TP_methylase PF00590.20 AAAP01003866.1_24 - 4.7e-29 101.8 1.1 6.6e-29 101.4 1.1 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UPF0102 PF02021.17 AAAP01003866.1_25 - 1.8e-17 63.3 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DUF1853 PF08907.11 AAAP01003866.1_25 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1853) NERD PF08378.11 AAAP01003866.1_25 - 0.0078 16.7 0.0 0.013 16.0 0.0 1.3 1 1 0 1 1 1 1 Nuclease-related domain Hjc PF01870.18 AAAP01003866.1_25 - 0.011 15.7 0.1 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) BON PF04972.17 AAAP01003866.1_26 - 7.6e-23 80.6 8.7 4.5e-12 46.1 1.4 2.3 2 0 0 2 2 2 2 BON domain B3_4 PF03483.17 AAAP01003866.1_26 - 0.091 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain Transglut_core2 PF13369.6 AAAP01003866.1_27 - 5e-34 117.1 0.8 6.1e-34 116.8 0.1 1.5 2 0 0 2 2 2 1 Transglutaminase-like superfamily TPR_9 PF13371.6 AAAP01003866.1_27 - 7.1e-16 58.1 4.6 2.5e-15 56.4 4.6 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003866.1_27 - 0.057 13.6 0.3 1.4 9.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GSH-S_ATP PF02955.16 AAAP01003866.1_28 - 6e-74 247.2 0.0 8.9e-74 246.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AAAP01003866.1_28 - 1.1e-44 151.3 0.2 1.7e-44 150.8 0.2 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AAAP01003866.1_28 - 5.6e-19 68.5 0.0 7.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AAAP01003866.1_28 - 1.5e-05 24.4 0.1 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AAAP01003866.1_28 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GSP_synth PF03738.14 AAAP01003866.1_28 - 0.05 12.8 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp ATPgrasp_ST PF14397.6 AAAP01003866.1_28 - 0.14 11.4 0.1 2.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp EAL PF00563.20 AAAP01003866.1_29 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 EAL domain FKBP_C PF00254.28 AAAP01003866.1_30 - 0.0093 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1885 PF08968.10 AAAP01003866.1_30 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Mg_chelatase PF01078.21 AAAP01003866.1_31 - 9.5e-95 315.8 0.0 1.5e-94 315.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 AAAP01003866.1_31 - 1e-39 135.1 0.0 1.7e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 AAAP01003866.1_31 - 2.6e-28 98.5 5.9 5e-28 97.6 5.9 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 AAAP01003866.1_31 - 7.7e-08 31.7 0.0 6.1e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 AAAP01003866.1_31 - 1.3e-07 31.7 0.0 3.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AAAP01003866.1_31 - 4.4e-06 26.5 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_32 PF13654.6 AAAP01003866.1_31 - 0.0059 15.5 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 AAAP01003866.1_31 - 0.01 15.9 0.0 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 AAAP01003866.1_31 - 0.023 14.8 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003866.1_31 - 0.026 14.9 0.0 0.3 11.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003866.1_31 - 0.029 14.6 0.0 0.096 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003866.1_31 - 0.031 14.7 1.2 0.084 13.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 AAAP01003866.1_31 - 0.063 13.0 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 AAAP01003866.1_31 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 AAAP01003866.1_31 - 0.22 11.0 0.0 1.6 8.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region HIT PF01230.23 AAAP01003866.1_33 - 1.9e-25 89.5 0.0 2.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AAAP01003866.1_33 - 1.9e-14 54.1 0.0 2.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PRA-PH PF01503.17 AAAP01003866.1_34 - 8.5e-19 67.8 0.0 1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TRL PF13146.6 AAAP01003866.1_34 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TRL-like protein family His_biosynth PF00977.21 AAAP01003866.1_35 - 2.7e-91 305.1 0.6 3.1e-91 304.9 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 AAAP01003866.1_35 - 2.5e-05 23.9 2.5 0.0033 16.8 0.7 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AAAP01003866.1_35 - 5e-05 22.7 2.0 0.021 14.1 0.5 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 AAAP01003866.1_35 - 0.00011 21.4 1.5 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 AAAP01003866.1_35 - 0.0011 18.4 0.1 0.041 13.3 0.0 2.2 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 AAAP01003866.1_35 - 0.0028 17.0 0.1 0.54 9.6 0.1 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase Dus PF01207.17 AAAP01003866.1_35 - 0.0045 16.1 0.1 0.67 9.0 0.0 2.1 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AAAP01003866.1_35 - 0.0067 15.7 0.1 2.3 7.3 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 AAAP01003866.1_35 - 0.57 9.2 4.7 0.34 9.9 0.1 2.3 1 1 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 AAAP01003866.1_36 - 8.6e-11 41.7 0.1 9.3e-11 41.6 0.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAAP01003866.1_36 - 0.0002 20.6 0.0 0.0002 20.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 AAAP01003866.1_36 - 0.016 14.6 0.2 0.017 14.5 0.2 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase DUF561 PF04481.12 AAAP01003866.1_36 - 0.068 12.3 0.1 0.068 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF561) His_biosynth PF00977.21 AAAP01003866.1_37 - 2e-51 174.7 0.0 2.4e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AAAP01003866.1_37 - 4.5e-05 22.7 0.1 0.0002 20.6 0.1 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) GATase PF00117.28 AAAP01003866.1_38 - 3.7e-20 72.5 0.0 4.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AAAP01003866.1_38 - 7.3e-06 25.9 0.9 0.00011 22.0 0.9 2.2 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AAAP01003866.1_38 - 5.4e-05 23.1 0.0 0.039 13.8 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 AAAP01003866.1_38 - 0.00033 20.3 0.0 0.00049 19.8 0.0 1.3 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 AAAP01003866.1_38 - 0.13 11.3 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain IGPD PF00475.18 AAAP01003866.1_39 - 5.8e-67 224.5 0.3 7.9e-67 224.0 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PQQ PF01011.21 AAAP01003867.1_1 - 3.8e-42 140.3 13.3 9.6e-09 34.8 0.0 8.5 8 0 0 8 8 8 6 PQQ enzyme repeat PQQ_2 PF13360.6 AAAP01003867.1_1 - 8.8e-32 110.6 7.7 3.4e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AAAP01003867.1_1 - 1.4e-22 79.5 25.4 2.2e-06 28.0 0.1 9.1 8 1 0 8 8 8 5 PQQ-like domain ssDBP_DBD PF18361.1 AAAP01003867.1_1 - 0.0067 16.6 0.1 8.9 6.4 0.0 4.2 5 0 0 5 5 5 1 Single stranded DNA-binding protein ss DNA binding domain SUKH-4 PF14435.6 AAAP01003867.1_1 - 0.034 14.2 0.0 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 SUKH-4 immunity protein Kelch_6 PF13964.6 AAAP01003867.1_1 - 0.12 12.7 0.1 4 7.9 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Response_reg PF00072.24 AAAP01003867.1_2 - 2.1e-23 82.6 0.0 3.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003867.1_2 - 6.6e-21 73.6 1.5 9.3e-21 73.1 1.5 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003867.1_2 - 1.9e-06 27.4 0.4 3.6e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003867.1_2 - 3.7e-05 23.2 0.4 0.00011 21.7 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_40 PF14493.6 AAAP01003867.1_2 - 0.0067 16.9 0.3 0.019 15.4 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 AAAP01003867.1_2 - 0.0073 16.4 0.4 0.018 15.1 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003867.1_2 - 0.0097 15.7 0.1 0.031 14.1 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 AAAP01003867.1_2 - 0.012 15.6 0.1 0.049 13.7 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF2089 PF09862.9 AAAP01003867.1_2 - 0.034 14.2 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_10 PF04967.12 AAAP01003867.1_2 - 0.046 13.5 0.6 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_38 PF13936.6 AAAP01003867.1_2 - 0.047 13.5 0.5 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain SHOCT PF09851.9 AAAP01003867.1_4 - 2.3e-06 27.1 0.6 4.9e-06 26.1 0.6 1.6 1 0 0 1 1 1 1 Short C-terminal domain DMAP_binding PF06464.11 AAAP01003867.1_4 - 0.0011 19.8 2.8 0.0012 19.6 0.0 2.4 3 0 0 3 3 3 1 DMAP1-binding Domain GET2 PF08690.10 AAAP01003867.1_4 - 0.036 13.7 0.2 0.044 13.4 0.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Borrelia_P83 PF05262.11 AAAP01003867.1_4 - 0.038 12.5 0.2 0.05 12.1 0.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 AAAP01003867.1_4 - 0.11 12.8 6.3 0.18 12.2 6.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 AAAP01003867.1_4 - 0.13 12.9 5.6 0.36 11.5 5.6 1.7 1 0 0 1 1 1 0 SlyX DUF3138 PF11336.8 AAAP01003867.1_4 - 0.16 10.5 4.9 0.23 10.1 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TonB_dep_Rec PF00593.24 AAAP01003867.1_5 - 1.1e-43 150.8 19.6 1.4e-43 150.5 19.6 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAAP01003867.1_5 - 2.5e-12 47.3 0.2 6.4e-12 46.0 0.2 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF779 PF05610.11 AAAP01003867.1_6 - 8.1e-42 141.4 0.0 9.5e-42 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF779) Aldedh PF00171.22 AAAP01003867.1_7 - 4.2e-161 536.6 0.0 4.7e-161 536.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 AAAP01003867.1_7 - 0.032 14.3 0.7 0.077 13.0 0.7 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated QRPTase_C PF01729.19 AAAP01003867.1_8 - 5.2e-37 127.2 0.3 7.3e-37 126.7 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AAAP01003867.1_8 - 1.2e-17 63.7 0.1 3.2e-17 62.4 0.1 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TrkA_N PF02254.18 AAAP01003867.1_8 - 0.095 13.0 1.0 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Glyco_transf_4 PF13439.6 AAAP01003867.1_8 - 0.11 12.6 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase Family 4 TMP-TENI PF02581.17 AAAP01003867.1_8 - 0.11 11.9 6.8 0.14 11.5 3.5 2.5 2 1 0 2 2 2 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 AAAP01003867.1_8 - 0.52 9.7 2.1 1.3 8.4 0.2 2.1 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family NPCBM_assoc PF10633.9 AAAP01003867.1_8 - 2.7 8.3 9.8 0.17 12.2 3.2 2.5 3 1 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase NifQ PF04891.12 AAAP01003867.1_9 - 1.1e-52 178.6 0.0 1.3e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 NifQ SBP_bac_11 PF13531.6 AAAP01003867.1_10 - 9.5e-17 61.5 0.3 1.5e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Nitro_FeMo-Co PF02579.17 AAAP01003867.1_10 - 2.6e-10 40.5 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor TOBE PF03459.17 AAAP01003867.1_11 - 8.5e-14 51.6 0.2 9.2e-14 51.5 0.2 1.0 1 0 0 1 1 1 1 TOBE domain Rad9_Rad53_bind PF08605.10 AAAP01003867.1_11 - 0.042 14.0 0.1 0.049 13.8 0.1 1.1 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding IRK_C PF17655.1 AAAP01003867.1_13 - 1.2e-26 93.4 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 AAAP01003867.1_13 - 2.9e-10 39.9 2.6 3.6e-10 39.7 1.8 1.5 1 1 0 1 1 1 1 Ion channel IRK PF01007.20 AAAP01003867.1_13 - 1.5e-08 34.6 0.4 3.7e-07 30.0 0.4 2.3 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain SBF_like PF13593.6 AAAP01003867.1_14 - 4.1e-96 322.0 11.1 4.6e-96 321.8 11.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 AAAP01003867.1_14 - 3.3e-13 49.7 7.7 3.3e-13 49.7 7.7 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family MFS_1 PF07690.16 AAAP01003867.1_15 - 3.2e-41 141.4 67.6 2.1e-27 96.0 38.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01003867.1_15 - 6.1e-33 114.6 48.8 4.3e-32 111.8 48.8 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 AAAP01003867.1_15 - 4.3e-05 22.6 14.9 0.003 16.5 0.0 3.6 1 1 2 4 4 4 3 MFS_1 like family LacY_symp PF01306.19 AAAP01003867.1_15 - 5.2e-05 22.2 10.0 0.016 14.0 0.2 2.3 2 1 0 2 2 2 2 LacY proton/sugar symporter Sugar_tr PF00083.24 AAAP01003867.1_15 - 6.2 5.6 41.0 1.3 7.8 3.7 3.2 2 1 1 3 3 3 0 Sugar (and other) transporter Pyr_redox_2 PF07992.14 AAAP01003867.1_16 - 1.3e-66 224.9 3.3 1.5e-66 224.6 3.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAAP01003867.1_16 - 5.7e-33 113.5 0.1 1e-32 112.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAAP01003867.1_16 - 2.8e-21 75.9 9.5 3.3e-21 75.6 0.5 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003867.1_16 - 1.1e-15 57.7 0.4 4.4e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003867.1_16 - 2.3e-05 23.3 3.5 0.026 13.3 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 AAAP01003867.1_16 - 4.1e-05 22.9 0.1 0.003 16.7 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 AAAP01003867.1_16 - 0.00077 18.9 2.2 0.0015 17.9 1.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAAP01003867.1_16 - 0.00087 18.7 0.4 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AAAP01003867.1_16 - 0.0009 19.3 0.2 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 AAAP01003867.1_16 - 0.0096 15.2 0.2 0.028 13.6 0.2 1.9 1 0 0 1 1 1 1 Thi4 family XdhC_C PF13478.6 AAAP01003867.1_16 - 0.071 13.6 0.1 8.5 6.9 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_2 PF00890.24 AAAP01003867.1_16 - 1.3 8.0 8.7 0.44 9.6 4.0 2.5 3 1 1 4 4 4 0 FAD binding domain MCPsignal PF00015.21 AAAP01003867.1_17 - 1.1e-30 106.7 26.2 1.1e-30 106.7 26.2 3.6 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAAP01003867.1_17 - 7.2e-11 42.0 0.4 7.2e-11 42.0 0.4 4.4 3 2 0 3 3 2 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AAAP01003867.1_17 - 8.9e-09 35.6 0.9 9.4e-08 32.3 0.1 3.5 3 0 0 3 3 3 1 HAMP domain HBM PF16591.5 AAAP01003867.1_17 - 2.9e-08 33.4 1.0 2.9e-08 33.4 1.0 3.7 2 1 0 3 3 3 1 Helical bimodular sensor domain DUF1664 PF07889.12 AAAP01003867.1_17 - 0.034 14.2 18.8 0.13 12.3 2.3 4.3 3 3 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003867.1_17 - 0.046 14.0 33.3 0.43 10.9 3.9 6.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 AAAP01003867.1_17 - 0.31 10.9 3.5 22 4.9 0.0 3.5 2 2 1 3 3 3 0 Sec34-like family Laminin_II PF06009.12 AAAP01003867.1_17 - 0.49 10.4 31.1 0.39 10.7 0.8 4.8 2 1 2 4 4 4 0 Laminin Domain II GldM_N PF12081.8 AAAP01003867.1_17 - 0.53 10.3 18.4 1.3 9.0 0.3 3.8 1 1 2 3 3 3 0 GldM N-terminal domain TACC_C PF05010.14 AAAP01003867.1_17 - 2.7 7.7 16.7 1.5 8.6 0.0 3.2 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PGF-CTERM PF18204.1 AAAP01003867.1_17 - 9.5 6.4 10.6 2.2 8.4 5.2 2.7 2 0 0 2 2 2 0 PGF-CTERM motif Radical_SAM PF04055.21 AAAP01003867.1_18 - 1.1e-11 45.4 0.0 1.5e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily IDEAL PF08858.10 AAAP01003867.1_18 - 0.26 11.1 1.3 0.52 10.1 1.3 1.5 1 0 0 1 1 1 0 IDEAL domain Amidase PF01425.21 AAAP01003867.1_19 - 4.9e-68 230.1 1.4 8.1e-53 180.0 3.3 2.0 2 0 0 2 2 2 2 Amidase EAL PF00563.20 AAAP01003867.1_20 - 1.7e-55 188.2 0.0 2.7e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 EAL domain PAS_3 PF08447.12 AAAP01003867.1_20 - 0.0027 17.9 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003867.1_20 - 0.0083 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003867.1_20 - 0.029 14.6 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold AP_endonuc_2 PF01261.24 AAAP01003867.1_20 - 0.14 11.6 0.0 7.6 5.9 0.0 3.2 4 0 0 4 4 4 0 Xylose isomerase-like TIM barrel Peripla_BP_6 PF13458.6 AAAP01003867.1_21 - 6.8e-68 229.8 1.5 8.1e-68 229.6 1.5 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 AAAP01003867.1_21 - 7e-21 74.6 0.2 6.1e-20 71.5 0.2 2.1 1 1 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 AAAP01003867.1_21 - 1.4e-14 54.0 0.0 2.3e-14 53.3 0.0 1.3 1 1 0 1 1 1 1 Receptor family ligand binding region BPD_transp_2 PF02653.16 AAAP01003867.1_22 - 1.6e-40 139.0 43.9 1.8e-40 138.8 43.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AAAP01003867.1_23 - 6.3e-40 137.0 34.9 6.3e-40 137.0 34.9 1.5 1 1 1 2 2 2 2 Branched-chain amino acid transport system / permease component DUF5455 PF17537.2 AAAP01003867.1_23 - 6.8 7.2 14.4 1.7 9.1 0.8 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5455) ABC_tran PF00005.27 AAAP01003867.1_25 - 1.5e-30 106.5 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003867.1_25 - 1.3e-15 58.0 0.4 4.1e-07 30.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003867.1_25 - 2.6e-05 24.8 0.0 3.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 AAAP01003867.1_25 - 0.0011 18.1 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain AAA_25 PF13481.6 AAAP01003867.1_25 - 0.0021 17.6 0.4 0.015 14.9 0.2 2.3 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 AAAP01003867.1_25 - 0.0033 16.9 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003867.1_25 - 0.0049 17.3 0.4 0.01 16.3 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003867.1_25 - 0.0061 16.3 0.5 0.023 14.4 0.5 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AAAP01003867.1_25 - 0.0064 15.8 0.1 0.026 13.8 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 AAAP01003867.1_25 - 0.0065 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 AAAP01003867.1_25 - 0.0094 13.5 0.1 0.013 13.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BCA_ABC_TP_C PF12399.8 AAAP01003867.1_25 - 0.011 15.7 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter AAA_15 PF13175.6 AAAP01003867.1_25 - 0.017 14.9 0.0 0.031 14.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 AAAP01003867.1_25 - 0.028 13.2 0.0 2 7.1 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_27 PF13514.6 AAAP01003867.1_25 - 0.031 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AAAP01003867.1_25 - 0.032 14.1 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 AAAP01003867.1_25 - 0.043 14.1 0.3 0.79 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003867.1_25 - 0.05 13.7 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AAAP01003867.1_25 - 0.061 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 AAAP01003867.1_25 - 0.074 13.3 0.6 0.21 11.8 0.2 2.0 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 AAAP01003867.1_25 - 0.078 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 AAAP01003867.1_25 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003867.1_25 - 0.12 12.5 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain POR PF01558.18 AAAP01003867.1_27 - 1.2e-23 84.1 0.1 1.4e-23 83.9 0.1 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4 PF00037.27 AAAP01003867.1_28 - 5.4e-12 45.0 20.0 2.5e-08 33.4 2.1 2.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003867.1_28 - 6e-09 35.9 8.8 6e-09 35.9 8.8 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003867.1_28 - 3.5e-08 33.1 11.4 7.3e-05 22.6 1.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AAAP01003867.1_28 - 8.6e-08 31.9 15.9 0.0001 22.2 2.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003867.1_28 - 2.4e-07 31.6 12.0 8.7e-05 23.4 2.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AAAP01003867.1_28 - 6.3e-06 26.7 14.1 0.0015 19.0 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003867.1_28 - 3e-05 24.1 14.9 9.2e-05 22.5 14.7 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003867.1_28 - 0.00016 21.7 16.6 0.002 18.2 15.8 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAAP01003867.1_28 - 0.00073 20.2 10.8 0.15 12.8 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_17 PF13534.6 AAAP01003867.1_28 - 0.004 17.7 11.7 0.019 15.5 0.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003867.1_28 - 0.0055 17.2 14.3 0.057 14.0 5.1 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AAAP01003867.1_28 - 0.13 12.8 14.0 2.2 9.0 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAAP01003867.1_28 - 0.38 11.6 15.2 0.92 10.4 3.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 AAAP01003867.1_28 - 0.61 10.2 5.5 0.37 10.9 0.8 2.0 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_8 PF13183.6 AAAP01003867.1_28 - 0.79 10.2 17.2 1.1 9.7 3.2 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain POR_N PF01855.19 AAAP01003867.1_29 - 1.1e-44 152.9 0.2 2.5e-44 151.7 0.0 1.5 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 AAAP01003867.1_29 - 1.2e-30 105.8 0.2 1.9e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AAAP01003867.1_29 - 5e-06 26.4 0.1 1e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pyr_redox_2 PF07992.14 AAAP01003867.1_30 - 8.4e-52 176.2 0.7 1.2e-51 175.7 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003867.1_30 - 2.3e-15 56.9 0.1 8.1e-15 55.1 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003867.1_30 - 5.3e-06 25.9 0.0 2.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AAAP01003867.1_30 - 1e-05 25.3 3.7 0.0018 17.9 0.8 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003867.1_30 - 4.6e-05 23.6 0.2 9.9e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AAAP01003867.1_30 - 5.6e-05 22.6 1.6 0.19 11.0 0.4 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 AAAP01003867.1_30 - 0.00029 19.6 1.2 0.036 12.8 0.4 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 AAAP01003867.1_30 - 0.00045 19.4 6.3 0.017 14.2 2.1 2.3 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 AAAP01003867.1_30 - 0.0011 18.8 0.4 0.0018 18.2 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AAAP01003867.1_30 - 0.0038 16.5 0.7 0.0074 15.6 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AAAP01003867.1_30 - 0.0061 15.8 0.1 0.0096 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Rubredoxin_C PF18267.1 AAAP01003867.1_30 - 0.0094 15.9 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_7 PF13241.6 AAAP01003867.1_30 - 0.037 14.5 0.1 0.075 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AAAP01003867.1_30 - 0.044 13.4 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 AAAP01003867.1_30 - 0.14 11.2 0.9 0.33 10.0 0.3 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAAP01003867.1_30 - 1 8.3 6.0 0.35 9.9 0.4 2.5 4 0 0 4 4 4 0 Lycopene cyclase protein TPP_enzyme_C PF02775.21 AAAP01003867.1_31 - 2.9e-19 69.4 0.1 4.6e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_6 PF12837.7 AAAP01003867.1_31 - 1.4e-14 53.4 30.6 4.5e-06 26.5 0.7 4.8 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_11 PF13247.6 AAAP01003867.1_31 - 7.6e-11 42.0 8.3 7.6e-11 42.0 8.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003867.1_31 - 4.5e-08 33.6 29.8 0.00025 21.5 9.6 3.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003867.1_31 - 5.1e-08 32.9 29.6 0.0012 18.9 10.1 3.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003867.1_31 - 1.1e-07 31.9 30.0 0.0011 19.1 11.2 3.6 1 1 4 5 5 5 5 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003867.1_31 - 3.4e-07 30.0 32.0 0.051 13.7 1.6 4.8 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003867.1_31 - 0.00069 19.7 28.8 0.0033 17.5 7.8 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003867.1_31 - 0.012 16.6 29.3 0.88 10.6 3.3 4.7 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 AAAP01003867.1_31 - 0.021 15.7 5.0 0.021 15.7 5.0 5.3 5 0 0 5 5 4 0 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003867.1_31 - 0.046 13.6 44.1 0.078 12.8 2.5 5.6 5 1 0 5 5 5 0 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003867.1_31 - 2.6 8.6 30.6 2.3 8.8 0.9 4.9 3 2 1 4 4 4 0 4Fe-4S dicluster domain Fer4_19 PF06902.11 AAAP01003867.1_31 - 4.9 7.3 10.5 24 5.1 0.1 3.5 2 1 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4_8 PF13183.6 AAAP01003867.1_31 - 5.3 7.6 31.5 0.18 12.3 8.2 3.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain FTR1 PF03239.14 AAAP01003867.1_32 - 9.9e-27 93.9 19.0 1.3e-26 93.6 19.0 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family CcmD PF04995.14 AAAP01003867.1_32 - 0.85 9.8 6.9 4.7 7.4 0.3 3.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) cNMP_binding PF00027.29 AAAP01003867.1_33 - 2.4e-17 62.7 0.0 3.4e-08 33.4 0.0 3.0 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 AAAP01003867.1_33 - 6.6e-09 35.6 0.0 2.8e-08 33.5 0.0 2.0 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Hemerythrin PF01814.23 AAAP01003867.1_33 - 1.7e-08 35.1 5.3 3.2e-08 34.3 5.3 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactamase_B PF00753.27 AAAP01003867.1_33 - 3.8e-08 33.6 0.1 8.4e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Aminotran_1_2 PF00155.21 AAAP01003867.1_34 - 2e-80 270.7 0.0 2.3e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01003867.1_34 - 1.2e-05 24.0 0.0 2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AAAP01003867.1_34 - 0.00022 20.3 0.0 0.0005 19.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01003867.1_34 - 0.024 13.9 0.1 0.034 13.4 0.1 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AAAP01003867.1_34 - 0.48 9.7 2.4 0.93 8.7 1.0 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 AAAP01003867.1_35 - 2.4e-95 319.6 0.0 3e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF2190 PF09956.9 AAAP01003867.1_38 - 1.8e-20 73.3 9.3 2.2e-20 73.0 9.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2190) STAS_2 PF13466.6 AAAP01003867.1_39 - 0.0029 17.9 0.7 0.0036 17.6 0.7 1.1 1 0 0 1 1 1 1 STAS domain gpW PF02831.15 AAAP01003867.1_39 - 0.067 13.1 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 gpW Mu-like_gpT PF10124.9 AAAP01003867.1_40 - 1.5e-11 44.2 0.0 3.1e-05 23.4 0.0 2.1 1 1 1 2 2 2 2 Mu-like prophage major head subunit gpT Peptidase_S78 PF04586.17 AAAP01003867.1_40 - 0.00015 22.0 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 Caudovirus prohead serine protease Phage_portal_2 PF05136.13 AAAP01003867.1_41 - 1.3e-99 333.8 0.0 1.6e-99 333.5 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein, lambda family FLgD_tudor PF13861.6 AAAP01003867.1_43 - 0.00087 19.5 0.0 0.013 15.7 0.0 3.1 2 1 0 2 2 2 1 FlgD Tudor-like domain DUF3787 PF12655.7 AAAP01003867.1_44 - 0.11 12.4 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) ADP_ribosyl_GH PF03747.14 AAAP01003868.1_1 - 4.9e-22 79.0 0.1 1.3e-21 77.6 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase HNH_2 PF13391.6 AAAP01003868.1_3 - 3.8e-12 46.2 0.4 1.3e-11 44.4 0.4 2.0 1 1 0 1 1 1 1 HNH endonuclease WYL PF13280.6 AAAP01003868.1_4 - 2.9e-33 115.3 0.2 5.8e-33 114.4 0.2 1.5 1 0 0 1 1 1 1 WYL domain HD_2 PF12917.7 AAAP01003868.1_5 - 6.4e-09 35.8 0.1 4.4e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD_3 PF13023.6 AAAP01003868.1_5 - 0.00017 21.6 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 AAAP01003868.1_5 - 0.0016 18.2 0.1 0.0024 17.6 0.1 1.5 1 1 0 1 1 1 1 HD domain Sel1 PF08238.12 AAAP01003868.1_6 - 2.1e-12 47.3 1.3 6.1e-07 29.9 0.1 2.4 2 0 0 2 2 2 2 Sel1 repeat Uteroglobin PF01099.17 AAAP01003868.1_6 - 0.0029 17.9 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 Uteroglobin family Sel1 PF08238.12 AAAP01003868.1_7 - 1.7e-64 212.7 40.6 1.4e-06 28.8 0.0 10.7 11 0 0 11 11 11 10 Sel1 repeat TPR_16 PF13432.6 AAAP01003868.1_7 - 0.0047 17.6 19.4 1.1 10.0 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003868.1_7 - 0.012 15.3 4.2 27 4.5 0.0 5.4 5 0 0 5 5 5 0 TPR repeat PPR PF01535.20 AAAP01003868.1_7 - 0.63 10.4 2.5 64 4.1 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.6 AAAP01003868.1_7 - 5.4 8.1 19.5 2.9 9.0 0.1 6.6 6 2 1 7 7 7 0 Tetratricopeptide repeat PLDc_2 PF13091.6 AAAP01003868.1_9 - 2.9e-08 33.7 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Tyr-DNA_phospho PF06087.12 AAAP01003868.1_9 - 0.00095 18.2 0.0 0.31 9.9 0.0 2.1 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase DUF4726 PF15855.5 AAAP01003868.1_9 - 0.013 15.7 0.1 0.04 14.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) SDA1 PF05285.12 AAAP01003868.1_9 - 0.069 12.6 0.7 0.11 11.9 0.7 1.2 1 0 0 1 1 1 0 SDA1 RNase_H_2 PF13482.6 AAAP01003868.1_10 - 4.2e-32 111.4 0.1 7.2e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 RNase_H superfamily AAA_12 PF13087.6 AAAP01003868.1_10 - 6.2e-25 88.0 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AAAP01003868.1_10 - 3.1e-17 63.2 0.1 2.6e-08 34.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 AAAP01003868.1_10 - 2.5e-11 43.6 0.3 8.1e-11 42.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AAAP01003868.1_10 - 2.3e-08 34.5 0.1 7.3e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAAP01003868.1_10 - 3.2e-05 23.6 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 AAAP01003868.1_10 - 0.00039 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 AAAP01003868.1_10 - 0.00058 19.2 0.0 0.0022 17.3 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 AAAP01003868.1_10 - 0.0027 17.5 0.3 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 AAAP01003868.1_10 - 0.0049 16.1 0.3 0.0098 15.1 0.3 1.4 1 0 0 1 1 1 1 PIF1-like helicase PhoH PF02562.16 AAAP01003868.1_10 - 0.027 13.9 0.2 0.095 12.1 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.12 AAAP01003868.1_10 - 0.032 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 AAAP01003868.1_10 - 0.032 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 AAAP01003868.1_10 - 0.071 13.5 0.2 0.23 11.9 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YCII PF03795.14 AAAP01003868.1_10 - 0.093 13.1 0.1 20 5.7 0.0 3.5 3 0 0 3 3 3 0 YCII-related domain PDDEXK_1 PF12705.7 AAAP01003868.1_10 - 0.14 12.0 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily ATPase PF06745.13 AAAP01003868.1_10 - 0.19 11.1 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 KaiC UvrD-helicase PF00580.21 AAAP01003868.1_10 - 0.34 10.4 0.6 1.5 8.2 0.1 2.0 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DDE_Tnp_1 PF01609.21 AAAP01003868.1_11 - 1.5e-07 31.3 0.0 4.8e-06 26.4 0.0 2.7 2 1 0 2 2 2 1 Transposase DDE domain HEPN_Apea PF18739.1 AAAP01003868.1_12 - 6e-14 52.3 0.1 1.1e-12 48.3 0.1 2.1 1 1 0 1 1 1 1 Apea-like HEPN DUF3040 PF11239.8 AAAP01003868.1_14 - 0.5 10.7 3.9 21 5.5 2.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Glyco_hydro_19 PF00182.19 AAAP01003868.1_15 - 8.8e-11 42.1 0.0 2.7e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 Chitinase class I Phage-tail_3 PF13550.6 AAAP01003868.1_16 - 3.5e-23 82.3 0.0 7.4e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Putative phage tail protein Lambda_tail_I PF06805.12 AAAP01003868.1_16 - 1.7e-08 34.7 0.3 4.5e-08 33.3 0.3 1.8 1 0 0 1 1 1 1 Bacteriophage lambda tail assembly protein I NLPC_P60 PF00877.19 AAAP01003868.1_17 - 1.5e-06 28.1 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family DUF1287 PF06940.11 AAAP01003868.1_17 - 0.23 11.1 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF1833 PF08875.11 AAAP01003868.1_18 - 3.4e-62 208.4 0.1 3.8e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1833) DUF736 PF05284.12 AAAP01003868.1_18 - 0.072 13.0 0.0 0.57 10.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF736) DUF3379 PF11859.8 AAAP01003868.1_19 - 0.011 15.1 0.4 0.013 14.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) RCC1 PF00415.18 AAAP01003868.1_21 - 1.1e-41 141.1 12.6 3.7e-12 46.7 0.4 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 AAAP01003868.1_21 - 7.2e-21 73.5 19.1 5.8e-06 26.0 0.3 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Baculo_PEP_C PF04513.12 AAAP01003868.1_24 - 0.075 13.1 18.6 0.36 10.9 2.9 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 AAAP01003868.1_24 - 0.1 13.0 6.7 13 6.2 0.1 4.5 4 1 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.12 AAAP01003868.1_24 - 0.16 12.0 6.8 7.2 6.7 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Transthyretin PF00576.21 AAAP01003868.1_24 - 0.67 10.7 3.3 3.9 8.2 0.2 3.1 3 0 0 3 3 3 0 HIUase/Transthyretin family MLTD_N PF06474.12 AAAP01003868.1_24 - 1.8 8.8 5.1 1.8 8.8 0.4 2.8 2 0 0 2 2 2 0 MltD lipid attachment motif Tape_meas_lam_C PF09718.10 AAAP01003868.1_26 - 5.2e-20 71.3 0.6 5.2e-20 71.3 0.6 3.7 4 0 0 4 4 4 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TMP_2 PF06791.13 AAAP01003868.1_26 - 6.5e-16 58.6 11.3 6.5e-16 58.6 11.3 3.9 3 1 0 3 3 3 1 Prophage tail length tape measure protein Plasmid_stab_B PF10784.9 AAAP01003868.1_28 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein DUF2384 PF09722.10 AAAP01003868.1_31 - 1.6e-12 47.2 0.1 2.4e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) HTH_Crp_2 PF13545.6 AAAP01003868.1_31 - 0.11 12.5 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RES PF08808.11 AAAP01003868.1_32 - 7.1e-28 97.5 0.4 1e-27 97.0 0.4 1.2 1 0 0 1 1 1 1 RES domain Phage_cap_E PF03864.15 AAAP01003868.1_35 - 1.7e-92 310.2 0.3 2e-92 309.9 0.3 1.0 1 0 0 1 1 1 1 Phage major capsid protein E HDPD PF02924.14 AAAP01003868.1_36 - 2.7e-27 95.2 0.2 3e-27 95.0 0.2 1.0 1 0 0 1 1 1 1 Bacteriophage lambda head decoration protein D Peptidase_S49 PF01343.18 AAAP01003868.1_37 - 2.2e-29 102.4 0.2 3.5e-29 101.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 AAAP01003868.1_37 - 0.0017 18.2 0.2 0.049 13.5 0.0 2.3 1 1 1 2 2 2 1 Clp protease HigB-like_toxin PF05015.13 AAAP01003868.1_38 - 3e-19 69.2 0.0 3.1e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB HTH_3 PF01381.22 AAAP01003868.1_39 - 1.2e-13 50.9 0.0 1.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003868.1_39 - 2.8e-06 27.3 0.0 3.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAAP01003868.1_39 - 3.3e-06 27.4 0.0 5.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAAP01003868.1_39 - 0.00023 21.0 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CENP-B_N PF04218.13 AAAP01003868.1_39 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_26 PF13443.6 AAAP01003868.1_39 - 0.15 12.5 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma54_DBD PF04552.13 AAAP01003868.1_39 - 0.16 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Phage_portal_2 PF05136.13 AAAP01003868.1_40 - 3.4e-106 355.4 0.0 4.7e-106 355.0 0.0 1.2 1 0 0 1 1 1 1 Phage portal protein, lambda family PspA_IM30 PF04012.12 AAAP01003868.1_41 - 0.024 14.2 0.3 0.025 14.2 0.3 1.0 1 0 0 1 1 1 0 PspA/IM30 family PRiA4_ORF3 PF07929.11 AAAP01003868.1_42 - 4.4e-58 195.8 0.1 5.2e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Saw1 PF11561.8 AAAP01003868.1_42 - 0.23 11.0 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Terminase_GpA PF05876.12 AAAP01003868.1_43 - 1.7e-205 683.8 1.5 2e-205 683.6 1.5 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.6 AAAP01003868.1_43 - 0.039 14.3 0.4 0.087 13.2 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF3489 PF11994.8 AAAP01003868.1_45 - 6.1e-31 106.3 0.1 1.6e-30 105.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3489) MarR_2 PF12802.7 AAAP01003868.1_45 - 0.0054 16.6 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 MarR family FrhB_FdhB_N PF04422.13 AAAP01003868.1_45 - 0.076 13.2 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Penicillinase_R PF03965.16 AAAP01003868.1_45 - 0.12 12.8 0.0 7.7 6.9 0.0 2.7 2 1 1 3 3 3 0 Penicillinase repressor DUF1495 PF07381.11 AAAP01003868.1_45 - 0.13 12.1 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Bac_DNA_binding PF00216.21 AAAP01003868.1_46 - 3.3e-24 84.9 0.4 3.6e-24 84.8 0.4 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein Ribosomal_L12 PF00542.19 AAAP01003868.1_46 - 0.0035 17.7 0.1 0.0058 16.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain HU-CCDC81_bac_2 PF18175.1 AAAP01003868.1_46 - 0.069 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-HIG PF18291.1 AAAP01003868.1_46 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif N6_N4_Mtase PF01555.18 AAAP01003868.1_47 - 1e-14 54.8 0.6 1.2e-12 48.1 0.6 2.7 1 1 0 1 1 1 1 DNA methylase ParBc PF02195.18 AAAP01003868.1_47 - 1.3e-11 44.6 0.0 4.2e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 ParB-like nuclease domain UPF0020 PF01170.18 AAAP01003868.1_47 - 0.025 14.3 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 HTH_Tnp_4 PF13613.6 AAAP01003868.1_48 - 0.0007 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_AsnC-type PF13404.6 AAAP01003868.1_48 - 0.0065 16.3 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 AAAP01003868.1_48 - 0.023 14.8 0.9 0.064 13.4 0.9 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AAAP01003868.1_48 - 0.026 14.3 0.3 0.069 13.0 0.2 1.8 1 1 0 1 1 1 0 Homeodomain-like domain D5_N PF08706.11 AAAP01003868.1_51 - 5.3e-23 82.0 0.2 2.7e-22 79.7 0.1 2.2 2 1 0 2 2 2 1 D5 N terminal like PDDEXK_1 PF12705.7 AAAP01003868.1_52 - 8.8e-05 22.5 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Endotoxin_C2 PF18449.1 AAAP01003868.1_53 - 0.037 14.3 0.1 0.061 13.7 0.1 1.3 1 0 0 1 1 1 0 Delta endotoxin ResIII PF04851.15 AAAP01003868.1_54 - 3.8e-17 62.8 0.0 6.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AAAP01003868.1_54 - 3.9e-12 46.5 0.0 1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UPF0547 PF10571.9 AAAP01003868.1_54 - 1.1e-08 35.0 2.9 2.1e-08 34.1 2.9 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DEAD PF00270.29 AAAP01003868.1_54 - 1.2e-07 31.6 0.2 7.6e-07 29.1 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 AAAP01003868.1_54 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 AAAP01003868.1_54 - 1.2e-05 25.1 0.1 3.2e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain zf-ribbon_3 PF13248.6 AAAP01003868.1_54 - 0.00064 19.0 2.8 0.0014 18.0 2.8 1.6 1 0 0 1 1 1 1 zinc-ribbon domain AAA_22 PF13401.6 AAAP01003868.1_54 - 0.0013 19.1 0.0 0.0045 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain zinc_ribbon_2 PF13240.6 AAAP01003868.1_54 - 0.0032 17.1 1.3 0.0032 17.1 1.3 1.7 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 AAAP01003868.1_54 - 0.028 14.4 0.3 0.061 13.4 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon THF_DHG_CYH_C PF02882.19 AAAP01003868.1_54 - 0.034 13.5 0.6 1.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2075 PF09848.9 AAAP01003868.1_54 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Acetone_carb_G PF08882.11 AAAP01003868.1_54 - 0.17 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Zn-ribbon_8 PF09723.10 AAAP01003868.1_54 - 0.17 12.0 1.8 5.4 7.2 0.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 AAAP01003868.1_54 - 0.17 11.4 1.2 1.4 8.5 1.2 2.3 1 1 0 1 1 1 0 TFIIB zinc-binding YhfH PF14149.6 AAAP01003868.1_54 - 0.44 10.6 2.1 1.1 9.2 0.5 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-tcix PF14952.6 AAAP01003868.1_54 - 4.1 7.1 5.0 12 5.7 0.5 2.6 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding AAA_24 PF13479.6 AAAP01003868.1_56 - 1.9e-42 145.2 0.0 2.3e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AAAP01003868.1_56 - 0.073 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 AAAP01003868.1_56 - 0.11 12.9 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AAAP01003868.1_56 - 0.22 12.0 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma70_r4_2 PF08281.12 AAAP01003868.1_59 - 0.00097 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003868.1_59 - 0.0015 18.0 0.2 0.0049 16.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 KORA PF16509.5 AAAP01003868.1_59 - 0.08 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor zinc_ribbon_10 PF10058.9 AAAP01003868.1_60 - 0.054 13.2 0.2 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_2 PF13831.6 AAAP01003868.1_60 - 1.2 8.7 4.4 0.9 9.1 1.1 2.0 2 0 0 2 2 2 0 PHD-finger Fumerase_C PF05683.12 AAAP01003869.1_1 - 6.8e-25 87.6 0.1 7.3e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 Fumarase C-terminus Rubrerythrin PF02915.17 AAAP01003869.1_2 - 1.4e-18 67.6 21.0 2.2e-16 60.5 14.3 3.0 2 1 0 2 2 2 2 Rubrerythrin Ferritin PF00210.24 AAAP01003869.1_2 - 0.00012 22.0 8.0 0.02 14.8 7.1 2.3 1 1 0 1 1 1 1 Ferritin-like domain DUF892 PF05974.12 AAAP01003869.1_2 - 0.13 12.3 7.9 1 9.4 2.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF892) Rubredoxin PF00301.20 AAAP01003869.1_3 - 1.9e-23 82.2 3.8 2.1e-23 82.0 3.8 1.0 1 0 0 1 1 1 1 Rubredoxin Zn-ribbon_8 PF09723.10 AAAP01003869.1_3 - 0.0042 17.2 1.2 0.071 13.2 1.1 2.1 1 1 0 1 1 1 1 Zinc ribbon domain Rubredoxin_2 PF18073.1 AAAP01003869.1_3 - 0.014 15.1 4.2 0.76 9.6 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-piccolo PF05715.13 AAAP01003869.1_3 - 0.034 14.3 0.4 0.37 11.0 0.1 2.0 2 0 0 2 2 2 0 Piccolo Zn-finger zf-C2H2_3 PF13878.6 AAAP01003869.1_3 - 0.041 13.7 0.5 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-RanBP PF00641.18 AAAP01003869.1_3 - 0.059 12.7 4.3 0.21 11.0 0.8 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others OrfB_Zn_ribbon PF07282.11 AAAP01003869.1_3 - 0.082 12.8 0.2 9.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 AAAP01003869.1_3 - 0.085 12.8 3.4 4.4 7.3 0.6 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain A2L_zn_ribbon PF08792.10 AAAP01003869.1_3 - 0.15 11.8 1.8 10 6.0 0.3 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Mss51 PF13824.6 AAAP01003869.1_3 - 0.16 12.1 4.4 0.41 10.8 0.4 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PHD_4 PF16866.5 AAAP01003869.1_3 - 0.23 11.6 4.2 0.7 10.0 4.2 1.7 1 1 0 1 1 1 0 PHD-finger zf-C2H2 PF00096.26 AAAP01003869.1_3 - 0.24 11.9 3.0 9 7.0 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 AAAP01003869.1_3 - 0.44 10.2 2.3 4.1 7.1 0.5 2.0 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 AAAP01003869.1_3 - 0.49 10.9 1.8 13 6.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Pyr_redox_2 PF07992.14 AAAP01003869.1_4 - 3.8e-49 167.5 0.0 4.8e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rbx_binding PF18113.1 AAAP01003869.1_4 - 5.2e-24 83.8 0.1 9.4e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 Rubredoxin binding C-terminal domain Pyr_redox PF00070.27 AAAP01003869.1_4 - 1.1e-14 54.7 0.1 2e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AAAP01003869.1_4 - 9e-05 22.6 1.5 0.12 12.6 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 AAAP01003869.1_4 - 0.0004 19.8 0.6 0.001 18.5 0.1 1.9 2 0 0 2 2 2 1 ThiF family K_oxygenase PF13434.6 AAAP01003869.1_4 - 0.0054 15.9 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 AAAP01003869.1_4 - 0.0062 15.9 0.0 0.079 12.3 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AAAP01003869.1_4 - 0.012 15.5 0.8 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AAAP01003869.1_4 - 0.022 14.3 7.4 3.9 6.9 0.3 3.8 2 2 1 4 4 4 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003869.1_4 - 0.023 14.0 0.6 4.7 6.4 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 AAAP01003869.1_4 - 0.026 13.6 0.8 4.2 6.3 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 AAAP01003869.1_4 - 0.039 14.2 0.0 9.2 6.6 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 AAAP01003869.1_4 - 0.072 12.3 3.8 2.3 7.4 0.2 2.6 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 AAAP01003869.1_4 - 0.082 12.0 2.7 0.22 10.6 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 AAAP01003869.1_4 - 0.11 13.0 0.0 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Cytochrom_C PF00034.21 AAAP01003869.1_5 - 1.3e-08 35.9 0.0 2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003869.1_5 - 0.0012 19.1 3.7 0.013 15.8 3.7 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Pilus_CpaD PF09476.10 AAAP01003869.1_5 - 0.17 11.6 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) ACR_tran PF00873.19 AAAP01003869.1_6 - 0 1128.1 13.7 0 1127.9 13.7 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003869.1_6 - 4.8e-11 42.2 37.7 2.3e-10 39.9 12.4 2.7 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AAAP01003869.1_6 - 0.0093 15.4 24.3 0.043 13.2 13.8 2.5 2 0 0 2 2 2 2 Protein export membrane protein HlyD_D23 PF16576.5 AAAP01003869.1_7 - 1.4e-14 53.8 0.0 2.6e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003869.1_7 - 2.9e-14 52.6 0.1 1.2e-12 47.4 0.0 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 AAAP01003869.1_7 - 1.3e-12 48.4 0.0 1.4e-07 32.1 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AAAP01003869.1_7 - 0.00071 19.4 0.1 0.0027 17.5 0.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD PF00529.20 AAAP01003869.1_7 - 0.0021 17.9 0.6 0.26 11.2 0.2 2.4 2 0 0 2 2 2 2 HlyD membrane-fusion protein of T1SS PAS_9 PF13426.7 AAAP01003869.1_8 - 3e-28 98.1 0.0 2.1e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAAP01003869.1_8 - 4.5e-25 88.0 1.2 2e-14 53.8 0.1 2.9 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAAP01003869.1_8 - 1.4e-24 86.2 0.0 1e-16 61.0 0.0 3.2 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAAP01003869.1_8 - 9e-24 84.1 0.0 2.3e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01003869.1_8 - 1.1e-23 83.4 0.0 4.1e-14 52.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AAAP01003869.1_8 - 3e-16 59.0 0.2 6.5e-08 32.4 0.0 3.7 4 0 0 4 4 4 2 PAS domain dCache_1 PF02743.18 AAAP01003869.1_8 - 1.1e-15 58.1 0.0 1.2e-14 54.8 0.0 2.1 2 0 0 2 2 2 1 Cache domain HisKA PF00512.25 AAAP01003869.1_8 - 8.5e-11 41.7 1.7 1.4e-10 41.1 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AAAP01003869.1_8 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_7 PF12860.7 AAAP01003869.1_8 - 0.0081 16.3 0.0 0.24 11.6 0.0 3.1 2 1 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AAAP01003869.1_8 - 0.079 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CIDE-N PF02017.15 AAAP01003869.1_8 - 0.19 11.8 0.0 25 5.0 0.0 2.6 2 0 0 2 2 2 0 CIDE-N domain Laminin_G_3 PF13385.6 AAAP01003869.1_9 - 0 1145.9 312.4 4.6e-24 85.3 7.1 25.1 25 0 0 25 25 22 18 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 AAAP01003869.1_9 - 6e-92 304.8 48.5 2e-08 34.9 0.0 19.8 19 0 0 19 19 18 15 Laminin G domain Laminin_G_1 PF00054.23 AAAP01003869.1_9 - 4.8e-44 149.7 45.7 2.2e-07 31.1 0.1 18.4 18 0 0 18 18 18 11 Laminin G domain Big_9 PF17963.1 AAAP01003869.1_9 - 1.2e-42 144.5 136.0 5.5e-11 43.1 6.8 54.7 52 9 5 57 57 29 20 Bacterial Ig domain Cadherin_5 PF17892.1 AAAP01003869.1_9 - 9e-27 92.9 158.2 1.2e-06 28.3 3.4 27.8 22 7 0 22 22 22 10 Cadherin-like domain HemolysinCabind PF00353.19 AAAP01003869.1_9 - 4.2e-25 87.3 236.0 1.4e-07 31.3 12.8 22.9 21 2 2 23 23 23 14 RTX calcium-binding nonapeptide repeat (4 copies) Pentaxin PF00354.17 AAAP01003869.1_9 - 9.1e-21 74.4 43.6 0.04 13.6 0.4 15.3 16 0 0 16 16 16 9 Pentaxin family Cadherin_3 PF16184.5 AAAP01003869.1_9 - 1.7e-18 66.6 2.6 9.6e-06 25.6 0.0 9.0 10 0 0 10 10 10 2 Cadherin-like Sialidase PF02973.16 AAAP01003869.1_9 - 5.8e-08 32.5 20.4 0.039 13.4 0.1 7.6 8 0 0 8 8 8 3 Sialidase, N-terminal domain FecR PF04773.13 AAAP01003869.1_9 - 2e-07 31.6 0.3 2e-07 31.6 0.3 6.4 5 0 0 5 5 4 1 FecR protein Toxin_R_bind_N PF07953.12 AAAP01003869.1_9 - 6.1e-07 29.4 5.7 2.9 7.6 0.5 8.7 9 0 0 9 9 9 1 Clostridium neurotoxin, N-terminal receptor binding Cadherin_4 PF17803.1 AAAP01003869.1_9 - 4.8e-06 27.1 38.7 0.00011 22.8 3.9 47.1 45 7 3 48 48 27 14 Bacterial cadherin-like domain BNR PF02012.20 AAAP01003869.1_9 - 0.077 13.0 20.7 1.4 9.2 1.0 6.5 4 0 0 4 4 4 0 BNR/Asp-box repeat Alginate_exp PF13372.6 AAAP01003869.1_10 - 3.5e-12 45.8 6.9 3.8e-12 45.6 5.0 2.0 2 1 0 2 2 2 1 Alginate export PilZ PF07238.14 AAAP01003869.1_11 - 2.4e-07 31.0 0.0 3.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 PilZ domain Tex_N PF09371.10 AAAP01003869.1_13 - 9.3e-72 240.5 0.1 1.5e-71 239.8 0.1 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 AAAP01003869.1_13 - 4.2e-51 172.6 0.0 8.9e-51 171.6 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 AAAP01003869.1_13 - 4.2e-25 87.8 0.0 1.2e-24 86.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 AAAP01003869.1_13 - 2.2e-24 86.1 0.0 6.7e-24 84.6 0.0 1.9 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 AAAP01003869.1_13 - 8.5e-23 80.5 1.2 2.1e-22 79.2 1.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 AAAP01003869.1_13 - 6.5e-06 26.0 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 AAAP01003869.1_13 - 0.00016 22.0 0.0 0.00031 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 AAAP01003869.1_13 - 0.00067 19.1 0.2 0.0031 16.9 0.0 2.0 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K FAD_binding_4 PF01565.23 AAAP01003869.1_13 - 0.001 18.8 0.4 0.0039 16.9 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain TetR_C_28 PF17937.1 AAAP01003869.1_14 - 2.5e-17 63.1 0.3 4.2e-17 62.4 0.1 1.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAAP01003869.1_14 - 2.8e-10 39.8 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAAP01003869.1_14 - 0.0027 17.9 0.1 0.021 15.0 0.0 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HlyD_D23 PF16576.5 AAAP01003869.1_15 - 2.2e-31 108.7 0.7 3.9e-31 107.9 0.7 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003869.1_15 - 1.2e-15 58.1 0.2 1.1e-14 55.0 0.0 2.5 2 1 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01003869.1_15 - 1.2e-06 28.3 0.7 1.2e-06 28.3 0.7 3.4 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD PF00529.20 AAAP01003869.1_15 - 0.1 12.5 9.1 0.28 11.1 0.3 2.4 2 0 0 2 2 2 0 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAAP01003869.1_15 - 0.65 9.9 7.9 0.43 10.4 0.2 3.4 4 0 0 4 4 4 0 Biotin-requiring enzyme ACR_tran PF00873.19 AAAP01003869.1_16 - 1.2e-241 804.5 13.5 1.4e-241 804.3 13.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AAAP01003869.1_16 - 6.3e-15 54.9 21.0 1.2e-11 44.1 9.3 2.8 2 0 0 2 2 2 2 MMPL family PALP PF00291.25 AAAP01003870.1_1 - 9.5e-33 113.8 1.3 1.1e-32 113.7 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiF PF00899.21 AAAP01003870.1_2 - 1.4e-60 204.7 0.0 1.8e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 AAAP01003870.1_2 - 0.019 15.6 0.6 0.044 14.4 0.4 1.7 1 1 0 1 1 1 0 PglD N-terminal domain Sacchrp_dh_NADP PF03435.18 AAAP01003870.1_2 - 0.054 13.8 0.3 0.1 12.9 0.3 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AAAP01003870.1_2 - 0.058 13.0 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 AAAP01003870.1_2 - 0.17 11.4 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DrsE_2 PF13686.6 AAAP01003870.1_3 - 5.3e-15 55.6 0.2 6.2e-13 48.9 0.2 2.0 1 1 0 1 1 1 1 DsrE/DsrF/DrsH-like family DrsE PF02635.15 AAAP01003870.1_3 - 1.2e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 DsrE/DsrF-like family DUF3390 PF11870.8 AAAP01003870.1_3 - 0.013 15.8 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Phosphoesterase PF04185.14 AAAP01003870.1_4 - 3.8e-93 312.5 0.0 4.5e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 AAAP01003870.1_4 - 0.00097 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase LTXXQ PF07813.12 AAAP01003870.1_5 - 4.5e-17 62.7 7.5 4.5e-17 62.7 7.5 1.5 1 1 1 2 2 2 1 LTXXQ motif family protein Metal_resist PF13801.6 AAAP01003870.1_5 - 0.00058 20.1 2.5 0.016 15.4 0.0 2.3 2 0 0 2 2 2 2 Heavy-metal resistance Pantoate_ligase PF02569.15 AAAP01003870.1_6 - 2.1e-96 322.3 0.0 2.3e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Pantoate_transf PF02548.15 AAAP01003870.1_7 - 4.1e-105 350.8 0.1 4.7e-105 350.6 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase HTH_Crp_2 PF13545.6 AAAP01003870.1_8 - 5.1e-20 71.2 0.0 9e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AAAP01003870.1_8 - 4.1e-17 61.5 0.0 1.1e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family cNMP_binding PF00027.29 AAAP01003870.1_8 - 7.5e-15 54.8 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Sigma70_r4_2 PF08281.12 AAAP01003870.1_8 - 0.0016 18.1 0.1 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01003870.1_8 - 0.011 15.6 0.1 0.051 13.4 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 AAAP01003870.1_8 - 0.018 14.6 0.0 0.053 13.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 AAAP01003870.1_8 - 0.023 14.1 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 AAAP01003870.1_8 - 0.027 14.4 0.0 0.27 11.1 0.0 2.6 3 0 0 3 3 3 0 MarR family HTH_11 PF08279.12 AAAP01003870.1_8 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 HTH domain MarR PF01047.22 AAAP01003870.1_8 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 AAAP01003870.1_8 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FixS PF03597.15 AAAP01003870.1_9 - 1.3e-21 76.1 3.2 1.5e-21 75.8 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type E1-E2_ATPase PF00122.20 AAAP01003870.1_10 - 3.2e-46 157.1 3.2 5.4e-46 156.4 0.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AAAP01003870.1_10 - 9.4e-32 111.0 0.2 1.8e-31 110.1 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AAAP01003870.1_10 - 1.7e-08 34.7 0.0 7.7e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain ATPase-cat_bd PF12156.8 AAAP01003870.1_10 - 1.6e-06 28.7 0.0 3.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Hydrolase_3 PF08282.12 AAAP01003870.1_10 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4342 PF14242.6 AAAP01003870.1_10 - 9.4 6.3 7.0 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) FixH PF05751.11 AAAP01003870.1_11 - 1.2e-39 135.8 0.0 1.3e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 FixH YtkA PF13115.6 AAAP01003870.1_11 - 2.1e-06 28.2 0.0 3.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 YtkA-like Fer4_18 PF13746.6 AAAP01003870.1_12 - 2.4e-39 134.0 7.0 6.8e-39 132.6 7.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AAAP01003870.1_12 - 6.8e-29 100.5 0.0 9.3e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_7 PF12838.7 AAAP01003870.1_12 - 8.8e-09 35.8 5.2 9.4e-05 22.9 1.5 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AAAP01003870.1_12 - 6.9e-08 32.5 6.5 8.6e-05 22.6 1.5 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003870.1_12 - 2.4e-07 31.2 5.7 0.00041 20.8 1.3 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003870.1_12 - 1.5e-06 28.5 4.5 0.0055 17.1 0.9 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_5 PF12801.7 AAAP01003870.1_12 - 3.2e-05 23.8 6.3 3.2e-05 23.8 6.3 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003870.1_12 - 0.00083 19.1 22.0 0.0046 16.7 4.5 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003870.1_12 - 0.00091 19.3 12.9 0.02 15.0 3.3 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003870.1_12 - 0.002 18.1 19.3 0.012 15.6 6.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003870.1_12 - 0.0088 16.5 3.3 0.0088 16.5 3.3 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AAAP01003870.1_12 - 0.025 14.7 3.2 0.025 14.7 3.2 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003870.1_12 - 0.06 14.3 15.0 0.33 11.9 4.9 2.8 1 1 3 4 4 4 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003870.1_12 - 0.31 11.2 18.2 1.5 9.0 16.1 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AAAP01003870.1_12 - 0.75 10.9 21.9 0.99 10.5 4.5 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_20 PF14691.6 AAAP01003870.1_12 - 2.6 7.8 6.0 7.7 6.3 6.0 1.7 1 1 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_15 PF13459.6 AAAP01003870.1_12 - 3.4 8.5 12.2 5.8 7.7 2.7 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain FixP_N PF14715.6 AAAP01003870.1_13 - 2.4e-25 88.0 8.2 4.6e-25 87.1 8.2 1.5 1 0 0 1 1 1 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrome_CBB3 PF13442.6 AAAP01003870.1_13 - 1.9e-23 82.5 1.0 3.4e-11 43.3 0.2 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003870.1_13 - 2.2e-17 64.0 0.2 4.7e-07 30.9 0.0 3.3 2 2 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 AAAP01003870.1_13 - 0.0045 16.7 0.2 1.1 9.0 0.0 2.7 2 1 1 3 3 3 2 Cytochrome c-550 domain Cytochrome_C7 PF14522.6 AAAP01003870.1_13 - 0.091 12.8 0.0 19 5.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c GSu_C4xC__C2xCH PF09698.10 AAAP01003870.1_13 - 3.3 8.5 7.4 42 5.0 0.1 3.2 2 1 1 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) FixQ PF05545.11 AAAP01003870.1_14 - 5.5e-15 55.1 0.6 6.2e-15 54.9 0.6 1.2 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ SLC3A2_N PF16028.5 AAAP01003870.1_14 - 0.033 13.7 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus FixO PF02433.15 AAAP01003870.1_15 - 4.4e-95 317.2 0.0 5.1e-95 317.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_C PF00034.21 AAAP01003870.1_15 - 1.6e-06 29.2 0.4 9.5e-05 23.5 0.4 2.2 1 1 0 1 1 1 1 Cytochrome c COX1 PF00115.20 AAAP01003870.1_16 - 5.7e-119 397.8 61.4 7.9e-119 397.3 61.4 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Methyltrans_SAM PF10672.9 AAAP01003870.1_17 - 4.9e-23 81.7 0.0 7.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PUA_3 PF17785.1 AAAP01003870.1_17 - 5.9e-20 70.8 0.0 1.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain Methyltransf_31 PF13847.6 AAAP01003870.1_17 - 4.8e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 AAAP01003870.1_17 - 8.5e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 AAAP01003870.1_17 - 1.1e-06 28.4 0.1 2.8e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.14 AAAP01003870.1_17 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AAAP01003870.1_17 - 0.00012 22.7 0.2 0.00031 21.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 AAAP01003870.1_17 - 0.0002 20.9 0.1 0.0003 20.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 AAAP01003870.1_17 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 AAAP01003870.1_17 - 0.0042 17.2 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N PF00107.26 AAAP01003870.1_17 - 0.014 15.3 0.5 0.03 14.3 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 AAAP01003870.1_17 - 0.042 14.5 0.3 0.12 13.0 0.2 1.9 2 1 0 2 2 1 0 Methyltransferase domain UPF0020 PF01170.18 AAAP01003870.1_17 - 0.046 13.4 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 LAL_C2 PF18603.1 AAAP01003870.1_17 - 0.055 13.6 0.8 15 5.9 0.1 3.4 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Methyltransf_23 PF13489.6 AAAP01003870.1_17 - 0.066 13.0 0.1 0.69 9.7 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain HTH_3 PF01381.22 AAAP01003870.1_18 - 7.8e-11 41.9 0.5 1.2e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003870.1_18 - 8.7e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003870.1_18 - 7.1e-05 22.8 0.1 0.00013 21.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003870.1_18 - 0.045 14.2 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HPP PF04982.13 AAAP01003870.1_19 - 8.1e-31 106.7 15.7 1.1e-30 106.3 13.2 1.9 2 0 0 2 2 2 1 HPP family Xan_ur_permease PF00860.20 AAAP01003870.1_20 - 1.7e-46 158.7 39.4 1.7e-46 158.7 39.4 1.7 1 1 1 2 2 2 2 Permease family AA_kinase PF00696.28 AAAP01003870.1_21 - 1.8e-44 152.1 2.5 2.1e-44 151.9 2.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family GatB_Yqey PF02637.18 AAAP01003870.1_21 - 0.011 15.6 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 GatB domain MMR_HSR1 PF01926.23 AAAP01003870.1_22 - 3.8e-22 78.5 0.0 5.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01003870.1_22 - 4.7e-09 36.4 0.2 2e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AAAP01003870.1_22 - 8.9e-08 31.8 0.1 1.5e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AAAP01003870.1_22 - 1.8e-06 28.1 0.1 0.00087 19.4 0.1 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 AAAP01003870.1_22 - 8e-05 22.3 0.2 0.0015 18.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 AAAP01003870.1_22 - 0.00033 20.0 1.6 0.1 11.8 0.2 2.3 2 1 0 2 2 2 2 Septin SRPRB PF09439.10 AAAP01003870.1_22 - 0.014 14.9 0.0 0.025 14.0 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 AAAP01003870.1_22 - 0.035 13.7 0.2 0.087 12.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 AAAP01003870.1_22 - 0.072 12.4 0.1 0.14 11.4 0.1 1.5 1 1 0 1 1 1 0 AIG1 family Roc PF08477.13 AAAP01003870.1_22 - 0.09 13.0 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 AAAP01003870.1_22 - 0.11 12.2 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AAAP01003870.1_22 - 0.13 12.8 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter YidC_periplas PF14849.6 AAAP01003870.1_23 - 1.2e-81 274.8 0.1 1.5e-81 274.4 0.1 1.2 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 AAAP01003870.1_23 - 5.1e-59 198.9 12.2 7.3e-59 198.4 12.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein YidD PF01809.18 AAAP01003870.1_24 - 2.4e-29 101.0 0.1 3e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Ribonuclease_P PF00825.18 AAAP01003870.1_25 - 5.3e-24 84.4 0.3 6.5e-24 84.1 0.3 1.0 1 0 0 1 1 1 1 Ribonuclease P THF_DHG_CYH_C PF02882.19 AAAP01003870.1_25 - 0.12 11.6 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_L34 PF00468.17 AAAP01003870.1_26 - 9.6e-23 79.9 10.1 1e-22 79.8 10.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Methyltransf_25 PF13649.6 AAAP01003870.1_27 - 4e-15 56.3 0.0 6.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003870.1_27 - 1.1e-13 51.6 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003870.1_27 - 1.7e-12 47.5 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003870.1_27 - 2.1e-10 40.6 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003870.1_27 - 1.8e-08 35.1 0.0 3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003870.1_27 - 9.3e-05 22.0 0.0 0.00013 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 AAAP01003870.1_27 - 0.00061 19.8 0.0 0.00091 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAAP01003870.1_27 - 0.0037 17.1 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 AAAP01003870.1_27 - 0.0044 16.3 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 AAAP01003870.1_27 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.12 AAAP01003870.1_27 - 0.0094 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 AAAP01003870.1_27 - 0.016 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 AAAP01003870.1_27 - 0.022 14.1 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 AAAP01003870.1_27 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase TrkA_N PF02254.18 AAAP01003870.1_27 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RrnaAD PF00398.20 AAAP01003870.1_27 - 0.21 10.6 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA-synt_1c PF00749.21 AAAP01003870.1_28 - 1.6e-48 165.3 0.0 1.8e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Abhydrolase_2 PF02230.16 AAAP01003870.1_29 - 2.3e-32 112.6 0.0 3e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 AAAP01003870.1_29 - 1.2e-06 28.3 0.0 1.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 AAAP01003870.1_29 - 1.3e-05 25.0 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 AAAP01003870.1_29 - 1.7e-05 24.4 0.0 0.00032 20.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AAAP01003870.1_29 - 8.2e-05 23.3 11.0 0.00037 21.2 9.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AAAP01003870.1_29 - 0.001 19.0 0.2 0.11 12.4 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 AAAP01003870.1_29 - 0.0012 18.8 0.0 0.38 10.6 0.1 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AAAP01003870.1_29 - 0.0015 17.8 0.6 1.1 8.5 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003870.1_29 - 0.0042 16.8 0.1 0.19 11.3 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold HNH_5 PF14279.6 AAAP01003870.1_30 - 9.2e-17 60.6 0.2 1.5e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 AAAP01003870.1_30 - 1.2e-13 50.9 0.1 2.3e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 AAAP01003870.1_30 - 2.5e-05 24.1 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease zf-C2H2 PF00096.26 AAAP01003870.1_30 - 0.0051 17.2 0.3 0.014 15.8 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 AAAP01003870.1_30 - 0.021 15.6 0.2 0.1 13.5 0.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 AAAP01003870.1_30 - 0.043 13.8 0.6 0.12 12.4 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Polysacc_deac_1 PF01522.21 AAAP01003870.1_31 - 4.6e-24 84.7 0.0 6.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Nitroreductase PF00881.24 AAAP01003870.1_32 - 7.4e-13 48.9 0.1 1.3e-12 48.2 0.1 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AAAP01003870.1_32 - 0.066 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative TM nitroreductase Pentapeptide PF00805.22 AAAP01003870.1_32 - 0.23 11.1 1.6 0.96 9.2 0.5 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) HD_3 PF13023.6 AAAP01003870.1_33 - 1.5e-52 177.9 0.2 1.8e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 AAAP01003870.1_33 - 4.9e-17 62.3 0.1 6.2e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AAAP01003870.1_33 - 0.0034 17.6 1.3 0.0066 16.7 1.3 1.4 1 0 0 1 1 1 1 HD domain MFS_3 PF05977.13 AAAP01003870.1_34 - 1.7e-35 122.4 31.3 2.2e-35 122.1 31.3 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AAAP01003870.1_34 - 3e-29 102.0 32.0 3e-29 102.0 32.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_TL5_C PF14693.6 AAAP01003870.1_35 - 1.3e-29 102.4 0.4 1.9e-29 101.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AAAP01003870.1_35 - 8.6e-23 80.7 0.0 3.4e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L25p family Pept_tRNA_hydro PF01195.19 AAAP01003870.1_36 - 8.6e-39 133.2 0.0 1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase YchF-GTPase_C PF06071.13 AAAP01003870.1_37 - 9.5e-41 137.9 0.5 2.4e-40 136.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AAAP01003870.1_37 - 3.8e-24 85.0 0.0 7.9e-24 83.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01003870.1_37 - 4.1e-08 32.9 0.0 1.5e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 AAAP01003870.1_37 - 0.17 11.3 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family UbiA PF01040.18 AAAP01003870.1_38 - 2e-28 99.4 23.9 2.6e-28 99.0 23.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family GGDEF PF00990.21 AAAP01003870.1_39 - 1.6e-45 154.8 0.1 2.1e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HSP90 PF00183.18 AAAP01003870.1_40 - 1.5e-125 420.1 0.0 1.4e-122 410.2 0.0 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 AAAP01003870.1_40 - 1.5e-10 41.0 0.0 2.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AAAP01003870.1_40 - 5.6e-08 33.3 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S30AE PF02482.19 AAAP01003870.1_41 - 3.3e-16 59.8 0.6 3.9e-16 59.6 0.6 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein DUF4478 PF14793.6 AAAP01003870.1_41 - 0.036 13.9 0.1 0.043 13.7 0.1 1.1 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF4795 PF16043.5 AAAP01003870.1_41 - 0.05 13.2 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) HTH_1 PF00126.27 AAAP01003870.1_42 - 3.3e-23 81.4 0.7 2.3e-22 78.7 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AAAP01003870.1_42 - 9.1e-18 64.4 1.1 1.4e-17 63.8 1.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 AAAP01003870.1_42 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 AAAP01003870.1_42 - 0.01 15.9 0.1 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 AAAP01003870.1_42 - 0.025 14.5 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 AAAP01003870.1_42 - 0.044 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran PF00005.27 AAAP01003870.1_45 - 4.9e-31 108.1 0.0 6.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003870.1_45 - 1.8e-10 41.1 0.1 9.5e-05 22.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003870.1_45 - 3.7e-09 36.3 0.4 1.8e-07 30.9 0.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003870.1_45 - 0.00023 20.8 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 AAAP01003870.1_45 - 0.00069 19.8 0.6 0.018 15.3 0.6 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AAAP01003870.1_45 - 0.00079 19.6 0.3 1 9.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AAAP01003870.1_45 - 0.0069 16.3 0.1 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.9 AAAP01003870.1_45 - 0.0073 15.3 0.0 0.0074 15.2 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AAAP01003870.1_45 - 0.0099 15.6 0.2 0.018 14.8 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003870.1_45 - 0.012 16.0 1.2 0.033 14.6 1.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 AAAP01003870.1_45 - 0.025 12.1 0.0 0.035 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DLIC PF05783.11 AAAP01003870.1_45 - 0.043 12.6 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 AAAP01003870.1_45 - 0.059 13.9 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AAAP01003870.1_45 - 0.064 12.6 0.0 0.14 11.5 0.1 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 AAAP01003870.1_45 - 0.094 12.9 0.4 0.34 11.2 0.2 1.9 1 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 AAAP01003870.1_45 - 0.23 10.6 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 AAAP01003870.1_45 - 0.28 10.8 0.0 0.36 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain CbiQ PF02361.16 AAAP01003870.1_46 - 8.8e-26 90.9 10.7 1.1e-25 90.5 10.7 1.0 1 0 0 1 1 1 1 Cobalt transport protein CbiM PF01891.16 AAAP01003870.1_48 - 7.9e-50 169.6 22.9 8.8e-50 169.4 22.9 1.0 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region DUF4198 PF10670.9 AAAP01003870.1_49 - 5.3e-46 157.7 0.1 6.2e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) EamA PF00892.20 AAAP01003870.1_50 - 1.1e-24 87.1 38.9 4.7e-14 52.7 17.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family LigT_PEase PF02834.16 AAAP01003870.1_53 - 8.3e-34 115.6 0.2 4e-16 59.0 0.1 2.0 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AAAP01003870.1_53 - 1.3e-15 57.7 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 AAAP01003870.1_53 - 1.8e-07 31.3 0.0 2.9e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain FIST_C PF10442.9 AAAP01003870.1_54 - 2.5e-26 92.2 0.0 4.7e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 AAAP01003870.1_54 - 1.3e-19 70.9 0.3 4.6e-17 62.6 0.2 2.3 2 0 0 2 2 2 2 FIST N domain Lipase_GDSL_2 PF13472.6 AAAP01003870.1_55 - 4e-25 89.3 0.1 4.6e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AAAP01003870.1_55 - 1.4e-12 48.0 0.0 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 AAAP01003870.1_55 - 0.027 14.6 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ABC_tran PF00005.27 AAAP01003870.1_56 - 2.8e-33 115.3 0.0 3.5e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003870.1_56 - 1.1e-05 25.4 0.0 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003870.1_56 - 0.00056 19.4 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003870.1_56 - 0.0018 17.9 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003870.1_56 - 0.0053 17.2 0.1 0.0065 16.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 AAAP01003870.1_56 - 0.026 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AAAP01003870.1_56 - 0.033 14.1 0.1 0.048 13.6 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 AAAP01003870.1_56 - 0.039 13.3 0.1 0.078 12.3 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAAP01003870.1_56 - 0.091 12.9 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAAP01003870.1_56 - 0.11 12.2 0.5 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AAAP01003870.1_56 - 0.15 12.3 0.1 3 8.2 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 AAAP01003870.1_56 - 0.18 12.0 0.2 1 9.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AAAP01003870.1_56 - 0.2 11.4 0.0 6.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsX PF02687.21 AAAP01003870.1_57 - 0.00032 21.1 6.8 0.00032 21.1 6.8 4.8 4 1 1 5 5 5 1 FtsX-like permease family Bax1-I PF01027.20 AAAP01003870.1_58 - 9.6e-66 221.5 31.4 1.1e-65 221.4 31.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DnaJ PF00226.31 AAAP01003870.1_59 - 2.5e-07 30.7 0.0 5.8e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain Mito_fiss_reg PF05308.11 AAAP01003870.1_59 - 0.0059 16.7 1.3 0.0059 16.7 1.3 1.5 2 0 0 2 2 2 1 Mitochondrial fission regulator CAP_N PF01213.19 AAAP01003870.1_59 - 0.0099 15.4 5.7 0.013 15.0 5.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Phe_hydrox_dim PF07976.12 AAAP01003871.1_1 - 8.5e-42 143.0 0.0 1.2e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.19 AAAP01003871.1_1 - 2.9e-17 63.0 0.0 3.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain TPR_20 PF14561.6 AAAP01003871.1_2 - 4.3e-31 107.1 1.6 4.3e-31 107.1 1.6 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.20 AAAP01003871.1_2 - 9.3e-28 96.2 0.0 1.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TPR_19 PF14559.6 AAAP01003871.1_2 - 3.8e-16 59.4 12.8 5.8e-13 49.1 1.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 AAAP01003871.1_2 - 7.4e-08 32.8 0.1 3.7e-07 30.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain TPR_16 PF13432.6 AAAP01003871.1_2 - 3.4e-06 27.6 14.8 0.013 16.2 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003871.1_2 - 4.3e-06 26.1 2.9 6.2e-06 25.6 2.9 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 AAAP01003871.1_2 - 1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TPR_14 PF13428.6 AAAP01003871.1_2 - 1e-05 25.9 16.7 0.04 14.7 3.1 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003871.1_2 - 1.1e-05 25.7 6.1 0.1 13.3 0.9 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 AAAP01003871.1_2 - 4.3e-05 23.7 0.0 0.00019 21.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 AAAP01003871.1_2 - 4.9e-05 23.2 0.0 9.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family ANAPC3 PF12895.7 AAAP01003871.1_2 - 0.00021 21.4 0.1 0.81 10.0 0.2 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 OST3_OST6 PF04756.13 AAAP01003871.1_2 - 0.0003 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DSBA PF01323.20 AAAP01003871.1_2 - 0.0007 19.4 5.1 0.036 13.8 0.0 2.8 2 2 1 3 3 3 2 DSBA-like thioredoxin domain Alkyl_sulf_dimr PF14863.6 AAAP01003871.1_2 - 0.0028 18.1 1.2 0.049 14.1 0.0 2.3 1 1 0 2 2 2 1 Alkyl sulfatase dimerisation Thioredoxin_3 PF13192.6 AAAP01003871.1_2 - 0.0093 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.10 AAAP01003871.1_2 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin TPR_12 PF13424.6 AAAP01003871.1_2 - 0.023 15.0 6.4 1.4 9.3 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003871.1_2 - 0.024 15.0 0.8 6 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003871.1_2 - 0.058 13.5 8.0 0.084 13.0 3.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 AAAP01003871.1_2 - 0.088 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 AAAP01003871.1_2 - 0.14 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 AAAP01003871.1_2 - 0.17 12.0 0.4 8.5 6.5 0.0 3.0 2 2 1 3 3 3 0 Thioredoxin DUF1593 PF07632.11 AAAP01003871.1_2 - 0.2 11.1 0.0 0.46 9.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1593) TPR_2 PF07719.17 AAAP01003871.1_2 - 0.25 11.5 2.7 15 6.0 0.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat LON_substr_bdg PF02190.16 AAAP01003871.1_3 - 1.2e-18 67.8 0.0 2.9e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Trm112p PF03966.16 AAAP01003871.1_4 - 0.00027 21.4 0.0 0.00073 20.1 0.0 1.6 1 1 0 1 1 1 1 Trm112p-like protein DUF971 PF06155.12 AAAP01003871.1_5 - 1.1e-28 99.7 0.0 1.4e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF2442 PF10387.9 AAAP01003871.1_5 - 0.0083 16.4 0.0 0.33 11.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2442) tRNA_edit PF04073.15 AAAP01003871.1_6 - 5.2e-24 84.7 0.2 6.4e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain FAD_binding_3 PF01494.19 AAAP01003871.1_7 - 2e-29 102.9 0.0 2.8e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AAAP01003871.1_7 - 5e-06 25.8 0.3 0.28 10.2 0.5 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein SE PF08491.10 AAAP01003871.1_7 - 6.8e-05 22.1 0.2 0.00013 21.1 0.1 1.4 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 AAAP01003871.1_7 - 0.0002 20.7 0.2 0.59 9.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAAP01003871.1_7 - 0.012 14.5 0.2 2.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase XdhC_C PF13478.6 AAAP01003871.1_7 - 0.079 13.5 0.2 0.54 10.8 0.0 2.2 2 1 0 2 2 2 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 AAAP01003871.1_7 - 0.085 13.1 0.1 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain P-II PF00543.22 AAAP01003871.1_8 - 1e-43 148.0 1.6 1.2e-43 147.9 1.6 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AAAP01003871.1_8 - 0.0059 16.7 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) SHS2_FTSA PF02491.20 AAAP01003871.1_8 - 0.023 15.1 0.1 8.9 6.8 0.1 2.2 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA Cdc6_C PF09079.11 AAAP01003871.1_8 - 0.062 13.3 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain SecB PF02556.14 AAAP01003871.1_8 - 0.11 12.4 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit SecB DUF3574 PF12098.8 AAAP01003871.1_8 - 0.12 12.2 0.1 0.29 10.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) MSP1_C PF07462.11 AAAP01003871.1_10 - 1 8.0 1.7 1 8.0 1.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ammonium_transp PF00909.21 AAAP01003871.1_12 - 1.4e-92 310.5 29.6 1.5e-92 310.3 29.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Aminotran_1_2 PF00155.21 AAAP01003871.1_13 - 3.8e-33 115.2 0.0 4.5e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF697 PF05128.12 AAAP01003871.1_13 - 0.032 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) Cys_Met_Meta_PP PF01053.20 AAAP01003871.1_13 - 0.05 12.1 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FtsK_SpoIIIE PF01580.18 AAAP01003871.1_14 - 5.8e-65 219.0 0.2 9.5e-65 218.3 0.2 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_alpha PF17854.1 AAAP01003871.1_14 - 3.4e-29 101.0 0.0 5.9e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 AAAP01003871.1_14 - 5.3e-27 93.4 0.0 1.1e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_4TM PF13491.6 AAAP01003871.1_14 - 3.3e-16 59.5 19.1 1e-15 57.9 18.0 2.0 1 1 1 2 2 2 1 4TM region of DNA translocase FtsK/SpoIIIE AAA_10 PF12846.7 AAAP01003871.1_14 - 3.8e-06 26.1 0.0 0.0021 17.1 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 AAAP01003871.1_14 - 1.7e-05 25.0 0.1 3.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 AAAP01003871.1_14 - 0.002 17.2 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 AAAP01003871.1_14 - 0.0051 15.8 0.0 0.0094 14.9 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain TniB PF05621.11 AAAP01003871.1_14 - 0.0088 15.5 0.0 1 8.7 0.0 2.9 3 0 0 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 AAAP01003871.1_14 - 0.023 15.0 0.0 0.18 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01003871.1_14 - 0.067 13.5 0.2 0.41 11.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 AAAP01003871.1_14 - 0.074 12.8 0.1 0.3 10.8 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 AAAP01003871.1_14 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain LolA PF03548.15 AAAP01003871.1_15 - 1.2e-23 83.6 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA Exo_endo_phos PF03372.23 AAAP01003871.1_16 - 3.6e-23 82.3 0.2 4.1e-23 82.1 0.2 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AAAP01003871.1_16 - 0.0092 15.8 0.0 0.076 12.9 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Trans_reg_C PF00486.28 AAAP01003871.1_17 - 1.9e-16 59.9 0.0 3.9e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_20 PF12840.7 AAAP01003871.1_17 - 0.068 13.2 1.4 0.23 11.5 0.4 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain GTP_cyclohydro2 PF00925.20 AAAP01003871.1_18 - 1.4e-61 206.8 0.0 6.3e-61 204.7 0.0 2.0 3 0 0 3 3 3 1 GTP cyclohydrolase II DHBP_synthase PF00926.19 AAAP01003871.1_18 - 8.9e-06 25.3 0.4 0.05 13.1 0.0 2.3 2 0 0 2 2 2 2 3,4-dihydroxy-2-butanone 4-phosphate synthase Ala_racemase_N PF01168.20 AAAP01003871.1_20 - 1.5e-28 99.9 0.2 1.9e-28 99.6 0.2 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TMP-TENI PF02581.17 AAAP01003871.1_21 - 7.3e-20 71.1 0.0 1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase TPR_2 PF07719.17 AAAP01003871.1_22 - 2.5e-18 64.6 10.1 6.8e-05 22.7 0.1 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003871.1_22 - 6.5e-18 63.9 24.7 0.0017 19.0 0.2 6.4 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003871.1_22 - 3.1e-16 59.6 22.7 1e-06 29.1 4.0 4.9 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003871.1_22 - 1.6e-14 52.8 0.2 0.00039 20.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003871.1_22 - 3.5e-14 53.2 38.2 3.6e-07 30.7 3.7 5.1 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003871.1_22 - 2.6e-13 49.4 5.1 0.00064 19.3 0.4 4.0 3 0 0 3 3 3 3 TPR repeat TPR_17 PF13431.6 AAAP01003871.1_22 - 5.7e-13 48.3 11.8 0.017 15.4 0.0 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003871.1_22 - 7.1e-13 48.5 25.0 9.1e-07 28.9 1.9 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003871.1_22 - 1.2e-12 47.0 4.0 0.00056 19.6 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003871.1_22 - 1.1e-07 32.0 16.4 0.0091 16.3 5.5 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003871.1_22 - 1.7e-06 27.7 3.8 0.54 10.4 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003871.1_22 - 3e-05 24.1 1.3 0.21 11.8 0.0 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AAAP01003871.1_22 - 6.6e-05 23.3 4.1 12 6.8 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 AAAP01003871.1_22 - 0.0014 18.0 0.4 0.004 16.5 0.2 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 9 (heptosyltransferase) TPR_20 PF14561.6 AAAP01003871.1_22 - 0.0015 18.8 15.6 0.052 13.9 0.3 4.7 1 1 6 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003871.1_22 - 0.0032 16.7 11.9 0.015 14.5 7.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 AAAP01003871.1_22 - 0.02 14.4 0.1 0.02 14.4 0.1 1.7 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 AAAP01003871.1_22 - 0.074 12.9 0.6 0.074 12.9 0.6 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 AAAP01003871.1_22 - 0.14 12.5 16.1 2.2 8.7 0.1 3.9 2 1 2 4 4 4 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 AAAP01003871.1_22 - 0.48 10.1 6.6 0.33 10.6 0.4 2.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 AAAP01003871.1_22 - 2.3 9.1 37.7 0.37 11.6 0.8 7.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Porin_4 PF13609.6 AAAP01003871.1_23 - 2.4e-43 149.1 42.5 2.9e-43 148.8 42.5 1.1 1 0 0 1 1 1 1 Gram-negative porin DUF3576 PF12100.8 AAAP01003871.1_24 - 2.2e-43 146.5 0.0 2.8e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3576) tRNA-synt_1 PF00133.22 AAAP01003871.1_25 - 1.5e-66 225.0 1.1 5.3e-26 91.0 0.8 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 AAAP01003871.1_25 - 1.7e-65 220.0 0.0 2.4e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 AAAP01003871.1_25 - 3.1e-30 105.2 0.0 2.7e-20 72.5 0.0 4.1 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AAAP01003871.1_25 - 2.8e-19 69.6 0.0 2.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AAAP01003871.1_25 - 5.7e-05 22.6 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAAP01003871.1_25 - 0.00032 19.8 0.0 0.37 9.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (K) DNA_ligase_ZBD PF03119.16 AAAP01003871.1_25 - 0.044 13.8 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 AAAP01003871.1_25 - 0.12 11.8 3.1 1.7 8.2 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 AAAP01003871.1_25 - 0.14 12.2 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon LptE PF04390.12 AAAP01003871.1_26 - 3.5e-10 40.5 1.3 4.8e-10 40.1 1.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide-assembly ComFB PF10719.9 AAAP01003871.1_26 - 0.0067 16.5 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 Late competence development protein ComFB DNA_pol3_delta PF06144.13 AAAP01003871.1_27 - 7.9e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delt_C PF14840.6 AAAP01003871.1_27 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Lipase_GDSL_2 PF13472.6 AAAP01003871.1_28 - 9.8e-16 58.7 0.1 2.5e-14 54.1 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Bac_GDH PF05088.12 AAAP01003871.1_29 - 0 2121.5 0.0 0 2121.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase DUF1866 PF08952.11 AAAP01003871.1_29 - 0.092 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) SIS_2 PF13580.6 AAAP01003871.1_30 - 2.4e-25 89.2 0.6 3e-25 88.9 0.6 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AAAP01003871.1_30 - 0.00054 19.8 0.1 0.021 14.6 0.0 2.2 1 1 1 2 2 2 1 SIS domain ADH_zinc_N PF00107.26 AAAP01003871.1_30 - 0.037 14.0 0.2 6.2 6.8 0.1 2.3 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Wzy_C PF04932.15 AAAP01003871.1_32 - 0.073 12.7 1.5 0.072 12.7 1.5 1.0 1 0 0 1 1 1 0 O-Antigen ligase Carbam_trans_N PF02543.15 AAAP01003871.1_33 - 3.7e-107 358.9 0.0 4.7e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Carbam_trans_C PF16861.5 AAAP01003871.1_33 - 1.5e-75 252.5 0.0 4.9e-75 250.8 0.0 1.8 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Peptidase_M22 PF00814.25 AAAP01003871.1_33 - 0.0015 18.3 0.0 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 Glycoprotease family Sua5_yciO_yrdC PF01300.18 AAAP01003871.1_33 - 0.038 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Telomere recombination Hepar_II_III PF07940.13 AAAP01003871.1_34 - 2e-23 83.3 0.3 4.4e-23 82.1 0.3 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein Hepar_II_III_N PF16889.5 AAAP01003871.1_34 - 8.5e-05 22.0 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 Heparinase II/III N-terminus Nsp3_PL2pro PF12124.8 AAAP01003871.1_34 - 0.027 14.3 0.1 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain Glycos_transf_2 PF00535.26 AAAP01003871.1_35 - 5.3e-30 104.5 0.0 6.8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003871.1_35 - 8.8e-21 74.8 0.9 4.7e-20 72.5 0.9 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003871.1_35 - 2e-14 53.8 0.0 3.7e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003871.1_35 - 8e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AAAP01003871.1_35 - 0.00067 19.6 0.3 0.001 19.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_1 PF00534.20 AAAP01003871.1_36 - 7.9e-31 106.9 0.0 1.2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003871.1_36 - 1.2e-25 90.5 0.2 2.8e-25 89.3 0.2 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003871.1_36 - 1.4e-08 35.0 0.0 3.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003871.1_36 - 0.00018 21.5 0.2 0.00034 20.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01003871.1_37 - 1.7e-31 109.0 0.0 2.7e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003871.1_37 - 1.4e-28 100.0 0.2 2.4e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003871.1_37 - 1.9e-07 31.7 3.0 1.9e-07 31.7 3.0 2.9 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAAP01003871.1_37 - 1.6e-05 25.2 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003871.1_37 - 4.7e-05 23.5 0.4 0.00017 21.7 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01003871.1_38 - 6.2e-16 58.6 0.0 4.2e-15 55.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3880 PF12996.7 AAAP01003871.1_38 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 DUF based on E. rectale Gene description (DUF3880) Glyco_transf_4 PF13439.6 AAAP01003871.1_38 - 0.05 13.6 0.3 0.65 10.0 0.1 2.3 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01003871.1_39 - 9.2e-16 57.8 0.0 2.8e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003871.1_39 - 1.8e-14 54.3 0.0 2.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003871.1_39 - 1.2e-08 35.2 0.0 2.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003871.1_39 - 1.4e-05 25.2 0.1 0.00017 21.6 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01003871.1_39 - 0.00057 20.4 0.3 0.00057 20.4 0.3 2.3 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Hepar_II_III PF07940.13 AAAP01003871.1_40 - 6.7e-64 215.8 0.2 1.1e-63 215.0 0.2 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein Hepar_II_III_N PF16889.5 AAAP01003871.1_40 - 2.8e-12 46.6 0.0 4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Heparinase II/III N-terminus Polysacc_synt_3 PF13440.6 AAAP01003871.1_41 - 1.6e-17 63.7 4.0 4.5e-17 62.2 4.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AAAP01003871.1_41 - 0.0026 17.2 12.6 0.0026 17.2 12.6 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein DUF1933 PF09147.10 AAAP01003871.1_41 - 0.14 11.7 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Glycos_transf_1 PF00534.20 AAAP01003871.1_42 - 9.9e-28 96.8 0.0 1.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003871.1_42 - 2.2e-25 89.6 0.1 5.2e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003871.1_42 - 1.2e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003871.1_42 - 0.018 15.1 0.2 0.076 13.0 0.1 2.3 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01003871.1_42 - 0.03 14.8 13.4 0.18 12.2 5.7 2.9 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain MannoseP_isomer PF01050.18 AAAP01003871.1_43 - 5.9e-67 224.3 0.2 8.3e-67 223.8 0.2 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AAAP01003871.1_43 - 1.2e-63 215.0 0.0 3.5e-63 213.5 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Cupin_2 PF07883.11 AAAP01003871.1_43 - 1e-11 44.4 0.1 2.3e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Cupin domain NTP_transf_3 PF12804.7 AAAP01003871.1_43 - 2.2e-08 34.6 4.3 4.4e-07 30.4 0.9 3.0 1 1 1 3 3 3 1 MobA-like NTP transferase domain Cupin_6 PF12852.7 AAAP01003871.1_43 - 0.00022 21.0 3.9 0.39 10.4 0.0 3.7 2 2 1 3 3 3 2 Cupin AraC_binding PF02311.19 AAAP01003871.1_43 - 0.00039 20.3 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.8 AAAP01003871.1_43 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Epimerase PF01370.21 AAAP01003871.1_44 - 2.1e-24 86.3 0.0 2.7e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AAAP01003871.1_44 - 7e-14 51.6 0.0 1.5e-10 40.7 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AAAP01003871.1_44 - 6.2e-12 45.8 0.0 8.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AAAP01003871.1_44 - 7.3e-12 44.9 0.0 2.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AAAP01003871.1_44 - 7.6e-12 45.3 0.0 6e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01003871.1_44 - 4.8e-11 42.3 0.0 6.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003871.1_44 - 0.00045 19.4 1.3 0.0047 16.1 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 AAAP01003871.1_44 - 0.028 14.4 1.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 KR domain Glycos_transf_4 PF00953.21 AAAP01003871.1_45 - 2e-28 99.4 12.4 2e-28 99.4 12.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 GFO_IDH_MocA PF01408.22 AAAP01003871.1_46 - 1.1e-20 74.6 0.4 1.2e-18 68.0 0.0 3.1 4 0 0 4 4 3 1 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.26 AAAP01003871.1_46 - 1.4e-15 57.4 0.2 5.8e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01003871.1_46 - 3.7e-05 23.1 1.5 3.7e-05 23.1 1.5 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 AAAP01003871.1_46 - 0.0009 18.6 0.2 0.36 10.2 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAAP01003871.1_46 - 0.0021 18.6 0.7 1.1 9.9 0.1 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 AAAP01003871.1_46 - 0.0022 17.6 0.1 0.004 16.7 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 AAAP01003871.1_46 - 0.0022 17.9 2.3 0.0024 17.8 0.4 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AAAP01003871.1_46 - 0.0075 16.9 3.1 0.011 16.4 0.1 2.7 3 0 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAAP01003871.1_46 - 0.013 15.7 3.8 0.032 14.5 0.1 2.8 3 0 0 3 3 2 0 TrkA-N domain ADH_zinc_N_2 PF13602.6 AAAP01003871.1_46 - 0.014 16.4 0.4 2.8 9.0 0.0 3.7 3 0 0 3 3 3 0 Zinc-binding dehydrogenase GFO_IDH_MocA_C PF02894.17 AAAP01003871.1_46 - 0.034 14.2 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain XdhC_C PF13478.6 AAAP01003871.1_46 - 0.074 13.6 2.7 1.4 9.5 0.1 3.1 3 0 0 3 3 3 0 XdhC Rossmann domain ApbA PF02558.16 AAAP01003871.1_46 - 0.1 12.2 0.7 0.32 10.6 0.2 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 AAAP01003871.1_46 - 1.1 9.5 3.4 6.5 7.0 0.1 3.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Polysacc_deac_1 PF01522.21 AAAP01003871.1_47 - 9.1e-20 70.8 0.0 1.3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Methyltransf_11 PF08241.12 AAAP01003871.1_48 - 5.8e-18 65.3 0.0 8.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003871.1_48 - 5.5e-16 59.1 0.0 9.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003871.1_48 - 3.1e-12 46.7 0.0 4.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003871.1_48 - 1.8e-11 44.6 0.0 3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003871.1_48 - 3.7e-09 36.6 0.0 6.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003871.1_48 - 3e-06 26.8 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 AAAP01003871.1_48 - 0.00021 20.3 0.0 0.00034 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PhnA_Zn_Ribbon PF08274.12 AAAP01003871.1_48 - 0.0032 17.4 1.4 0.0081 16.1 1.4 1.6 1 0 0 1 1 1 1 PhnA Zinc-Ribbon FtsJ PF01728.19 AAAP01003871.1_48 - 0.0041 17.2 0.0 0.0063 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 AAAP01003871.1_48 - 0.07 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 AAAP01003871.1_48 - 0.075 12.3 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Trm112p PF03966.16 AAAP01003871.1_48 - 0.1 13.2 0.5 0.52 10.9 0.7 2.0 1 1 0 1 1 1 0 Trm112p-like protein Zn_Tnp_IS91 PF14319.6 AAAP01003871.1_48 - 0.14 12.2 0.3 0.98 9.5 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain PrmA PF06325.13 AAAP01003871.1_48 - 0.15 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Zn-ribbon_8 PF09723.10 AAAP01003871.1_48 - 0.26 11.5 3.6 1.4 9.1 3.6 2.3 1 1 0 1 1 1 0 Zinc ribbon domain zf-ISL3 PF14690.6 AAAP01003871.1_48 - 0.45 11.2 3.1 2.9 8.6 0.6 3.0 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Asn_synthase PF00733.21 AAAP01003871.1_49 - 1.2e-56 193.0 0.0 1.5e-56 192.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003871.1_49 - 3e-40 137.0 0.0 4.6e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003871.1_49 - 2.1e-35 121.9 0.0 8e-35 120.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AAAP01003871.1_49 - 0.0011 18.5 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein CoA_binding_3 PF13727.6 AAAP01003871.1_50 - 4.1e-11 43.2 0.5 5.7e-11 42.7 0.5 1.2 1 0 0 1 1 1 1 CoA-binding domain CoA_binding PF02629.19 AAAP01003871.1_50 - 0.039 14.6 0.0 0.075 13.7 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Polysacc_synt_2 PF02719.15 AAAP01003871.1_51 - 5.5e-114 380.2 0.0 6.4e-114 380.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AAAP01003871.1_51 - 3.2e-21 75.9 0.0 2.9e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003871.1_51 - 2e-14 53.4 0.0 2.8e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AAAP01003871.1_51 - 1.6e-13 50.8 0.0 2.5e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003871.1_51 - 3.1e-11 42.8 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AAAP01003871.1_51 - 0.0012 18.4 0.0 0.0039 16.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AAAP01003871.1_51 - 0.021 14.0 0.6 0.31 10.2 0.1 2.3 2 1 1 3 3 3 0 Male sterility protein SIS_2 PF13580.6 AAAP01003871.1_52 - 1.6e-20 73.6 0.2 2e-20 73.2 0.2 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AAAP01003871.1_52 - 4.6e-10 39.5 0.2 8.1e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 SIS domain CCG PF02754.16 AAAP01003871.1_52 - 0.11 12.7 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich domain Wzy_C PF04932.15 AAAP01003871.1_53 - 1.7e-06 27.8 0.2 1.7e-06 27.8 0.2 3.8 3 2 0 3 3 3 1 O-Antigen ligase MIG-14_Wnt-bd PF06664.12 AAAP01003871.1_53 - 0.025 13.8 0.3 0.052 12.8 0.3 1.4 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion RNase_PH PF01138.21 AAAP01003872.1_1 - 7.1e-29 101.0 0.0 5.2e-26 91.7 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 AAAP01003872.1_1 - 2e-15 57.1 0.2 4e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_PH_C PF03725.15 AAAP01003872.1_1 - 4.1e-10 39.6 0.0 8.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ribosomal_S15 PF00312.22 AAAP01003872.1_2 - 8.5e-38 128.4 1.5 9.7e-38 128.3 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 FACT-Spt16_Nlob PF14826.6 AAAP01003872.1_2 - 0.01 15.6 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain TruB_N PF01509.18 AAAP01003872.1_3 - 2.2e-53 180.7 0.0 3e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AAAP01003872.1_3 - 5.4e-14 52.1 0.0 1.3e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AAAP01003872.1_3 - 0.00012 22.1 0.6 0.00058 19.9 0.1 2.3 2 0 0 2 2 2 1 Pseudouridine synthase II TruB, C-terminal TruB_C PF09142.11 AAAP01003872.1_3 - 0.0019 18.0 3.2 0.058 13.2 0.6 3.6 3 1 0 3 3 3 1 tRNA Pseudouridine synthase II, C terminal DJ-1_PfpI PF01965.24 AAAP01003872.1_4 - 1.8e-06 27.9 0.2 1.1e-05 25.2 0.2 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ATP-grasp_5 PF13549.6 AAAP01003872.1_4 - 0.036 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_M32 PF02074.15 AAAP01003872.1_5 - 1.2e-164 548.7 0.0 1.3e-164 548.6 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase OAD_gamma PF04277.13 AAAP01003872.1_7 - 1.8 9.2 3.7 2.3 8.8 3.6 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MeaB PF03308.16 AAAP01003872.1_8 - 2.5e-108 361.1 0.2 2.9e-108 360.9 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 AAAP01003872.1_8 - 1.2e-06 28.3 0.1 4.8e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AAAP01003872.1_8 - 4.6e-06 26.5 0.0 7.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 AAAP01003872.1_8 - 0.0021 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF463 PF04317.12 AAAP01003872.1_8 - 0.014 14.3 0.1 0.029 13.3 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 PALP PF00291.25 AAAP01003872.1_8 - 0.035 13.5 2.3 2.6 7.4 0.1 2.9 1 1 1 3 3 3 0 Pyridoxal-phosphate dependent enzyme Viral_helicase1 PF01443.18 AAAP01003872.1_8 - 0.036 13.8 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 AAAP01003872.1_8 - 0.053 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003872.1_8 - 0.064 13.3 0.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 AAAP01003872.1_8 - 0.12 11.8 0.0 9.8 5.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 AAAP01003872.1_8 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AAAP01003872.1_8 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AAAP01003872.1_8 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiC CheZ PF04344.13 AAAP01003872.1_9 - 8.3e-11 42.2 3.1 1.6e-09 38.0 3.1 2.0 1 1 1 2 2 2 2 Chemotaxis phosphatase, CheZ DUF4164 PF13747.6 AAAP01003872.1_9 - 0.074 13.3 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) MetJ PF01340.20 AAAP01003872.1_9 - 0.11 12.5 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ TrkH PF02386.16 AAAP01003872.1_10 - 7e-45 153.4 12.0 2.3e-44 151.7 12.0 1.7 1 1 0 1 1 1 1 Cation transport protein TrkH PF02386.16 AAAP01003872.1_11 - 3.1e-55 187.5 21.5 2.7e-31 108.6 7.1 2.0 2 0 0 2 2 2 2 Cation transport protein DUF5353 PF17304.2 AAAP01003872.1_11 - 0.024 14.4 0.5 0.024 14.4 0.5 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5353) DUF5423 PF17461.2 AAAP01003872.1_11 - 0.29 10.0 1.9 0.72 8.6 1.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Peptidase_M17 PF00883.21 AAAP01003872.1_12 - 2.2e-104 349.1 0.0 2.7e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain GST_N_3 PF13417.6 AAAP01003872.1_13 - 1.9e-14 53.8 0.0 3.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AAAP01003872.1_13 - 3.5e-12 46.5 0.0 5.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AAAP01003872.1_13 - 3.1e-11 43.4 0.0 4.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AAAP01003872.1_13 - 0.00011 22.1 0.1 0.00023 21.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AAAP01003872.1_13 - 0.011 16.5 0.0 0.02 15.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_4 PF14834.6 AAAP01003872.1_13 - 0.015 15.7 0.3 0.029 14.8 0.0 1.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AAAP01003872.1_13 - 0.18 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Toprim_4 PF13662.6 AAAP01003872.1_14 - 2.4e-24 85.6 0.1 5e-24 84.6 0.0 1.6 2 0 0 2 2 2 1 Toprim domain RecR PF02132.15 AAAP01003872.1_14 - 7.6e-15 54.2 1.2 1.6e-14 53.2 1.2 1.6 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AAAP01003872.1_14 - 0.0036 17.5 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Toprim domain YbaB_DNA_bd PF02575.16 AAAP01003872.1_15 - 2.9e-35 120.3 9.7 3.3e-35 120.2 9.7 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DNA_pol3_gamma3 PF12169.8 AAAP01003872.1_16 - 6.8e-57 191.4 4.1 1.5e-56 190.2 4.1 1.6 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_delta2 PF13177.6 AAAP01003872.1_16 - 1.1e-38 132.6 0.0 1.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF3646 PF12362.8 AAAP01003872.1_16 - 9.7e-38 129.0 0.6 2.1e-37 127.9 0.6 1.6 1 0 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal AAA PF00004.29 AAAP01003872.1_16 - 3.5e-11 43.6 0.8 1.9e-10 41.3 0.8 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003872.1_16 - 5.7e-06 26.7 0.0 0.00049 20.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AAAP01003872.1_16 - 1.4e-05 24.9 0.2 0.00029 20.6 0.0 2.3 1 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 AAAP01003872.1_16 - 3.6e-05 23.6 2.3 0.00011 21.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AAAP01003872.1_16 - 4.4e-05 23.5 0.2 0.3 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AAAP01003872.1_16 - 0.00033 20.7 0.1 0.0018 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 AAAP01003872.1_16 - 0.00094 18.5 0.5 0.79 8.9 0.1 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 AAAP01003872.1_16 - 0.002 18.7 0.0 0.004 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003872.1_16 - 0.0024 18.3 6.9 0.034 14.5 4.9 3.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.6 AAAP01003872.1_16 - 0.014 15.7 0.9 0.27 11.6 0.9 2.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AAAP01003872.1_16 - 0.017 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AAAP01003872.1_16 - 0.018 15.1 0.8 0.79 9.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_assoc_2 PF16193.5 AAAP01003872.1_16 - 0.022 15.1 0.1 0.062 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA C-terminal domain TsaE PF02367.17 AAAP01003872.1_16 - 0.12 12.4 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AAAP01003872.1_16 - 0.13 11.4 0.1 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Herpes_Helicase PF02689.14 AAAP01003872.1_16 - 0.18 9.7 0.2 0.27 9.1 0.2 1.2 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.15 AAAP01003872.1_16 - 0.28 11.1 1.5 0.51 10.2 0.6 1.8 2 0 0 2 2 2 0 NTPase NMT1_3 PF16868.5 AAAP01003872.1_17 - 9.1e-75 251.7 0.0 1e-74 251.6 0.0 1.0 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01003872.1_17 - 1.3e-07 31.5 0.5 8.7e-07 28.8 0.5 1.9 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAAP01003872.1_17 - 1.8e-07 31.3 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AAAP01003872.1_17 - 0.0063 16.2 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 NMT1-like family Response_reg PF00072.24 AAAP01003872.1_19 - 8.1e-24 83.9 0.2 9.1e-24 83.8 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain EAL PF00563.20 AAAP01003872.1_20 - 8.9e-75 251.3 0.0 1.8e-74 250.3 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003872.1_20 - 9.5e-40 136.0 0.0 2.2e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AAAP01003872.1_20 - 3.2e-29 101.2 0.0 2e-12 47.1 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AAAP01003872.1_20 - 9.1e-29 99.9 0.3 1.5e-11 44.5 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AAAP01003872.1_20 - 1.6e-25 89.3 0.0 3.3e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.7 AAAP01003872.1_20 - 1.9e-14 53.3 0.2 3.6e-06 26.9 0.0 4.8 4 0 0 4 4 4 3 PAS domain Response_reg PF00072.24 AAAP01003872.1_20 - 1.6e-13 50.8 0.0 5.9e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AAAP01003872.1_20 - 5.4e-08 32.8 0.0 5.4e-08 32.8 0.0 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Joubert PF15392.6 AAAP01003872.1_20 - 0.12 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated Nucleos_tra2_C PF07662.13 AAAP01003872.1_21 - 3.3e-61 206.7 5.8 3.3e-61 206.7 5.8 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 AAAP01003872.1_21 - 1e-21 77.3 2.4 1e-21 77.3 2.4 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 AAAP01003872.1_21 - 0.0024 18.1 6.5 0.0024 18.1 6.5 2.8 2 0 0 2 2 2 1 Nucleoside recognition FtsJ PF01728.19 AAAP01003872.1_23 - 1.1e-09 38.6 0.0 1.5e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Lip_A_acyltrans PF03279.13 AAAP01003872.1_24 - 1.3e-54 185.4 0.0 1.5e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase LpxK PF02606.14 AAAP01003872.1_25 - 1.5e-88 297.0 0.0 1.8e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Glycos_transf_N PF04413.16 AAAP01003872.1_26 - 4.1e-57 192.7 0.0 6.7e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) NQR2_RnfD_RnfE PF03116.15 AAAP01003872.1_26 - 0.092 12.2 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family DUF374 PF04028.13 AAAP01003872.1_27 - 4.9e-30 102.9 0.6 1.1e-29 101.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF374) ABC_membrane PF00664.23 AAAP01003872.1_28 - 1.9e-54 185.2 3.1 2.4e-54 184.8 3.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AAAP01003872.1_28 - 3.4e-33 115.0 0.0 7.3e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AAAP01003872.1_28 - 3e-08 33.4 0.0 2.8e-06 26.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003872.1_28 - 6.7e-05 23.3 0.3 0.00018 21.9 0.3 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003872.1_28 - 0.00015 21.8 0.0 0.00093 19.1 0.0 2.3 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 AAAP01003872.1_28 - 0.0013 19.0 0.1 0.011 16.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 AAAP01003872.1_28 - 0.0014 18.5 0.0 0.01 15.6 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_21 PF13304.6 AAAP01003872.1_28 - 0.0048 16.8 0.3 0.12 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AAAP01003872.1_28 - 0.0085 15.8 0.1 0.023 14.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AAAP01003872.1_28 - 0.0095 15.7 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 AAAP01003872.1_28 - 0.01 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_29 PF13555.6 AAAP01003872.1_28 - 0.012 15.4 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAAP01003872.1_28 - 0.018 13.9 0.4 0.1 11.4 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 AAAP01003872.1_28 - 0.04 14.3 0.1 0.9 10.0 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AAAP01003872.1_28 - 0.045 14.0 0.1 3.2 8.0 0.0 2.5 1 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003872.1_28 - 0.051 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AAAP01003872.1_28 - 0.065 12.5 0.0 0.2 10.9 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 AAAP01003872.1_28 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 AAAP01003872.1_28 - 0.18 11.9 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Cytochrom_C1 PF02167.15 AAAP01003872.1_29 - 7e-93 310.4 0.0 1.3e-92 309.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_B PF00033.19 AAAP01003872.1_29 - 3.2e-76 255.4 18.9 6.1e-76 254.5 18.9 1.5 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 AAAP01003872.1_29 - 1.9e-41 141.9 15.4 2.2e-40 138.5 10.4 2.6 2 0 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 AAAP01003872.1_29 - 2.7e-39 133.6 4.1 2.7e-39 133.6 4.1 3.6 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Ni_hydr_CYTB PF01292.20 AAAP01003872.1_29 - 0.0014 18.3 4.0 0.0014 18.3 4.0 4.8 2 1 1 4 4 4 2 Prokaryotic cytochrome b561 Cytochrome_CBB3 PF13442.6 AAAP01003872.1_29 - 0.057 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III UCR_Fe-S_N PF10399.9 AAAP01003872.1_30 - 5.2e-19 67.3 0.2 8.9e-19 66.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Rieske PF00355.26 AAAP01003872.1_30 - 7.6e-12 45.0 0.0 1.5e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 AAAP01003872.1_30 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence SpoU_methylase PF00588.19 AAAP01003872.1_31 - 4.5e-27 95.0 0.0 5e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Methyltransf_25 PF13649.6 AAAP01003872.1_32 - 4.6e-15 56.1 0.0 9.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003872.1_32 - 3.3e-13 50.2 0.0 5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003872.1_32 - 1e-11 45.3 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003872.1_32 - 1.2e-10 41.3 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003872.1_32 - 1.7e-08 34.4 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003872.1_32 - 7.9e-05 22.1 0.0 8.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 AAAP01003872.1_32 - 0.0023 17.4 0.0 0.0083 15.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 AAAP01003872.1_32 - 0.003 17.3 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AAAP01003872.1_32 - 0.0052 16.4 0.0 0.0083 15.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AAAP01003872.1_32 - 0.0064 16.1 0.0 0.008 15.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 AAAP01003872.1_32 - 0.038 12.9 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CheR PF01739.18 AAAP01003872.1_32 - 0.065 12.7 0.0 7.8 5.9 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_19 PF04672.12 AAAP01003872.1_32 - 0.11 12.0 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_34 PF11312.8 AAAP01003872.1_32 - 0.13 11.5 0.0 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase DUF938 PF06080.12 AAAP01003872.1_32 - 0.14 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.20 AAAP01003872.1_32 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SPOUT_MTase PF02590.17 AAAP01003872.1_34 - 3.9e-44 150.3 0.0 4.4e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase RsfS PF02410.15 AAAP01003872.1_35 - 1.2e-24 86.6 0.0 1.5e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation FbpC_C_terminal PF17845.1 AAAP01003872.1_35 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain Chal_sti_synt_C PF02797.15 AAAP01003872.1_35 - 0.16 11.9 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain CTP_transf_like PF01467.26 AAAP01003872.1_36 - 2.6e-19 69.8 0.0 3.1e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Aldedh PF00171.22 AAAP01003872.1_37 - 7.2e-14 51.1 3.5 2.8e-12 45.9 1.1 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Amidase_3 PF01520.18 AAAP01003872.1_38 - 2.4e-27 96.2 0.0 2.9e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AA_kinase PF00696.28 AAAP01003872.1_39 - 3.3e-42 144.7 0.6 4.6e-42 144.3 0.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 AAAP01003872.1_39 - 2.9e-22 78.4 0.2 2.9e-22 78.4 0.2 2.7 3 0 0 3 3 3 1 PUA domain PUA_3 PF17785.1 AAAP01003872.1_39 - 0.00053 19.7 0.1 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 PUA-like domain UPF0113 PF03657.13 AAAP01003872.1_39 - 0.00095 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain TruB_C PF09142.11 AAAP01003872.1_39 - 0.086 12.6 0.8 0.47 10.3 0.8 2.4 1 1 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Big_6 PF17936.1 AAAP01003872.1_39 - 0.09 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig domain GTP1_OBG PF01018.22 AAAP01003872.1_40 - 4.6e-60 201.7 3.4 4.6e-60 201.7 3.4 1.9 2 0 0 2 2 2 1 GTP1/OBG MMR_HSR1 PF01926.23 AAAP01003872.1_40 - 2.4e-25 88.8 0.0 3.7e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AAAP01003872.1_40 - 2e-13 50.2 0.0 1.2e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 AAAP01003872.1_40 - 0.046 13.2 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family Ribosomal_L27 PF01016.19 AAAP01003872.1_41 - 2.4e-38 130.0 2.6 2.7e-38 129.9 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 AAAP01003872.1_42 - 7.4e-40 135.3 3.1 8.2e-40 135.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF1289 PF06945.13 AAAP01003872.1_43 - 3e-13 49.4 0.7 3.4e-13 49.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) PFK PF00365.20 AAAP01003872.1_44 - 1e-48 166.2 0.0 1.2e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase BclA_C PF18573.1 AAAP01003872.1_44 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 BclA C-terminal domain DUF150 PF02576.17 AAAP01003872.1_45 - 6.6e-26 90.5 0.1 1.1e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 AAAP01003872.1_45 - 8.7e-14 51.4 0.0 2.7e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 RimP C-terminal SH3 domain TOBE PF03459.17 AAAP01003872.1_45 - 0.082 13.2 0.1 5.1 7.5 0.1 2.4 2 0 0 2 2 2 0 TOBE domain NusA_N PF08529.11 AAAP01003872.1_46 - 1.4e-36 125.5 5.6 1.8e-36 125.1 4.1 2.0 2 0 0 2 2 2 1 NusA N-terminal domain KH_5 PF13184.6 AAAP01003872.1_46 - 2.6e-31 107.5 1.0 3.4e-29 100.7 0.1 2.9 3 0 0 3 3 3 1 NusA-like KH domain HHH_5 PF14520.6 AAAP01003872.1_46 - 6.6e-08 33.1 2.1 0.0059 17.2 1.5 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain S1 PF00575.23 AAAP01003872.1_46 - 6.1e-06 26.5 0.0 2.1e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 S1 RNA binding domain KH_2 PF07650.17 AAAP01003872.1_46 - 2.8e-05 23.8 0.2 0.00034 20.4 0.0 2.7 2 0 0 2 2 2 1 KH domain KH_1 PF00013.29 AAAP01003872.1_46 - 0.00048 19.9 0.0 0.087 12.7 0.0 2.6 2 0 0 2 2 2 1 KH domain DUF448 PF04296.13 AAAP01003872.1_48 - 7.7e-21 73.7 0.0 1.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF448) Ribosomal_L7Ae PF01248.26 AAAP01003872.1_48 - 5.5e-06 26.0 0.0 9.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family IF2_assoc PF08364.11 AAAP01003872.1_49 - 2.7e-14 53.1 6.3 4.7e-14 52.4 6.3 1.3 1 0 0 1 1 1 1 Bacterial translation initiation factor IF-2 associated region DUF1682 PF07946.14 AAAP01003872.1_49 - 4.4 6.4 10.6 4.9 6.3 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) IF-2 PF11987.8 AAAP01003872.1_50 - 4.4e-38 129.6 0.2 1.4e-37 128.0 0.2 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 AAAP01003872.1_50 - 5.3e-33 114.2 9.1 1.7e-32 112.5 4.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 AAAP01003872.1_50 - 8.7e-16 57.5 0.0 2.5e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 AAAP01003872.1_50 - 1.2e-10 41.5 0.2 4.7e-10 39.6 0.2 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AAAP01003872.1_50 - 2.6e-09 37.3 9.5 1.8e-08 34.7 1.0 3.9 3 1 0 3 3 3 1 Elongation factor Tu domain 2 SRPRB PF09439.10 AAAP01003872.1_50 - 2.2e-07 30.5 0.5 1.4e-06 27.8 0.1 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 AAAP01003872.1_50 - 1.2e-05 24.9 1.0 3.6e-05 23.3 1.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 AAAP01003872.1_50 - 6.7e-05 22.4 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 AAAP01003872.1_50 - 0.0003 20.4 0.1 0.00055 19.6 0.1 1.4 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 AAAP01003872.1_50 - 0.00066 19.6 3.4 0.043 13.7 0.2 2.6 1 1 1 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 AAAP01003872.1_50 - 0.0011 18.7 0.1 0.0034 17.1 0.1 1.9 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 AAAP01003872.1_50 - 0.0015 18.6 0.0 0.39 10.8 0.0 3.0 1 1 0 1 1 1 1 Dynamin family Roc PF08477.13 AAAP01003872.1_50 - 0.0036 17.5 0.2 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 AAAP01003872.1_50 - 0.0062 16.5 0.6 0.024 14.7 0.1 2.3 2 1 1 3 3 3 1 C-terminal region of MMR_HSR1 domain Cul7 PF11515.8 AAAP01003872.1_50 - 0.012 15.9 0.2 0.061 13.6 0.0 2.1 1 1 1 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 SIS_2 PF13580.6 AAAP01003872.1_50 - 0.017 15.1 0.5 0.054 13.5 0.2 2.1 2 0 0 2 2 2 0 SIS domain RBFA PF02033.18 AAAP01003872.1_51 - 1.5e-25 89.7 0.0 1.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A TetR_C_7 PF14246.6 AAAP01003872.1_52 - 8.9e-26 90.3 1.6 1.7e-25 89.4 1.6 1.5 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AAAP01003872.1_52 - 9e-17 60.6 2.1 9e-17 60.6 2.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AAAP01003872.1_52 - 2.8e-10 40.5 2.9 2.8e-10 40.5 2.9 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAAP01003872.1_52 - 0.035 14.3 1.2 0.13 12.5 0.8 2.2 1 1 1 2 2 2 0 BetI-type transcriptional repressor, C-terminal Radical_SAM PF04055.21 AAAP01003872.1_54 - 1.4e-17 64.6 1.0 7.3e-17 62.3 1.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAAP01003872.1_54 - 0.00012 22.2 0.3 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAAP01003872.1_54 - 0.00014 22.1 0.2 0.00075 19.8 0.0 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain LGT PF01790.18 AAAP01003872.1_55 - 6.5e-17 61.6 3.8 8.3e-17 61.2 3.8 1.2 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase UvrD-helicase PF00580.21 AAAP01003872.1_56 - 5.3e-52 177.3 0.0 1.5e-51 175.8 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AAAP01003872.1_56 - 6.1e-20 72.0 0.0 5.2e-18 65.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 AAAP01003872.1_56 - 9.7e-18 64.7 0.0 1.5e-15 57.4 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AAAP01003872.1_56 - 2.1e-12 46.7 0.7 2.1e-05 24.2 0.9 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 AAAP01003872.1_56 - 7.7e-08 32.5 0.0 4.1e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 AAAP01003872.1_56 - 0.013 15.2 2.6 0.045 13.5 0.2 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 AAAP01003872.1_56 - 0.29 10.9 0.3 46 3.6 0.1 3.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 AAAP01003872.1_57 - 4.5e-57 191.5 0.0 6.7e-57 191.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AAAP01003872.1_57 - 1.4e-11 44.1 5.1 2.9e-11 43.1 5.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AAAP01003872.1_57 - 9.4e-10 38.6 0.0 2.5e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AAAP01003872.1_57 - 0.0059 15.7 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 2 MCM P-loop domain Sigma54_activat PF00158.26 AAAP01003872.1_57 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 AAAP01003872.1_57 - 0.056 13.2 0.0 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 AAAP01003872.1_57 - 0.085 12.2 0.1 1.8 7.9 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1285 PF06938.11 AAAP01003872.1_58 - 8.1e-55 184.9 0.0 9.2e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1285) NUDIX PF00293.28 AAAP01003872.1_59 - 8.4e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PolyA_pol PF01743.20 AAAP01003872.1_60 - 8e-29 100.6 0.1 1.8e-28 99.5 0.0 1.7 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AAAP01003872.1_60 - 4.9e-12 45.4 0.0 2.6e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 AAAP01003872.1_60 - 7.6e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Peroxin-22 PF12827.7 AAAP01003872.1_61 - 0.14 12.1 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family POC1 PF10450.9 AAAP01003872.1_61 - 0.25 10.3 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 POC1 chaperone UPF0160 PF03690.13 AAAP01003872.1_62 - 2.8e-77 260.5 0.0 3.2e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF2786 PF10979.8 AAAP01003872.1_63 - 7.5e-08 32.2 3.0 7.5e-08 32.2 3.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Histone_HNS PF00816.21 AAAP01003872.1_63 - 0.15 12.9 1.9 0.15 12.9 0.3 1.8 2 0 0 2 2 2 0 H-NS histone family GPS2_interact PF15784.5 AAAP01003872.1_63 - 0.16 12.4 2.8 3.8 8.0 1.3 2.3 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain UPF0114 PF03350.16 AAAP01003872.1_64 - 5.7e-37 126.5 1.8 5.7e-37 126.5 1.8 1.7 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 UXS1_N PF11803.8 AAAP01003872.1_64 - 0.056 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal GPDPase_memb PF10110.9 AAAP01003872.1_65 - 0.0038 16.0 2.2 0.0038 16.0 2.2 2.2 2 0 0 2 2 2 2 Membrane domain of glycerophosphoryl diester phosphodiesterase Peripla_BP_6 PF13458.6 AAAP01003872.1_66 - 1.8e-50 172.6 5.1 3e-50 171.8 5.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AAAP01003872.1_66 - 2.5e-18 66.3 0.0 5.1e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AAAP01003872.1_66 - 5.2e-14 52.0 0.0 8.6e-07 28.3 0.0 2.9 4 0 0 4 4 4 2 Periplasmic binding protein domain Neur_chan_LBD PF02931.23 AAAP01003872.1_66 - 2.7e-05 23.7 1.2 0.012 15.1 0.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 AAAP01003872.1_66 - 0.0017 18.5 1.8 0.0027 17.8 1.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Claudin_3 PF06653.11 AAAP01003872.1_66 - 0.82 9.6 10.7 1.4 8.9 10.7 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like RseC_MucC PF04246.12 AAAP01003872.1_66 - 1.6 8.7 5.1 0.35 10.8 1.0 1.9 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DctM PF06808.12 AAAP01003872.1_67 - 2.8e-73 247.1 38.9 3.5e-73 246.8 38.9 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component LapA_dom PF06305.11 AAAP01003872.1_67 - 0.1 12.4 0.2 0.1 12.4 0.2 5.4 5 1 1 6 6 6 0 Lipopolysaccharide assembly protein A domain SBP_bac_3 PF00497.20 AAAP01003873.1_1 - 4.1e-05 23.1 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HTH_39 PF14090.6 AAAP01003873.1_1 - 0.15 11.9 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Asn_synthase PF00733.21 AAAP01003873.1_2 - 3e-103 346.2 0.2 3.9e-103 345.9 0.2 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003873.1_2 - 9.6e-45 151.5 0.0 2.1e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003873.1_2 - 3.5e-42 143.8 0.0 1.4e-40 138.6 0.0 2.8 3 0 0 3 3 3 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAAP01003873.1_2 - 2.3e-05 23.7 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 AAAP01003873.1_2 - 7.9e-05 22.2 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 AAAP01003873.1_2 - 0.018 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 AAAP01003873.1_2 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase TPR_2 PF07719.17 AAAP01003873.1_3 - 3.2e-35 117.4 31.9 3.9e-06 26.6 0.4 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003873.1_3 - 4.8e-31 105.3 9.3 4.7e-05 23.0 0.2 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003873.1_3 - 2.6e-30 102.0 1.4 0.0022 18.1 0.0 8.9 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003873.1_3 - 6.5e-29 98.2 12.3 2.7e-05 24.3 0.0 9.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003873.1_3 - 6.3e-26 88.8 50.1 2.7e-05 24.6 2.1 9.9 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003873.1_3 - 6.2e-25 87.5 38.0 4.3e-06 27.1 8.4 6.9 5 1 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003873.1_3 - 1.9e-21 76.4 67.1 9.9e-07 29.3 4.9 7.0 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003873.1_3 - 4.9e-18 64.5 20.4 0.0036 17.0 0.6 9.4 3 2 7 10 10 10 7 TPR repeat TPR_12 PF13424.6 AAAP01003873.1_3 - 3.9e-15 55.9 44.3 5.2e-06 26.7 3.4 6.8 4 2 4 8 8 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003873.1_3 - 4.7e-13 49.2 10.6 0.011 15.9 0.0 5.0 3 1 1 5 5 4 4 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_23 PF13489.6 AAAP01003873.1_3 - 8.8e-13 48.4 0.0 2.9e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TPR_7 PF13176.6 AAAP01003873.1_3 - 1.3e-12 46.8 25.6 0.032 14.2 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003873.1_3 - 3.7e-12 46.1 18.2 0.23 12.2 0.0 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat Methyltransf_25 PF13649.6 AAAP01003873.1_3 - 8.4e-12 45.6 1.0 4.2e-11 43.4 0.1 2.7 3 0 0 3 3 2 1 Methyltransferase domain TPR_9 PF13371.6 AAAP01003873.1_3 - 1.3e-11 44.5 40.8 3.4e-05 23.9 0.3 6.5 2 1 3 7 7 6 5 Tetratricopeptide repeat Methyltransf_12 PF08242.12 AAAP01003873.1_3 - 2.6e-11 44.1 0.2 3.2e-10 40.6 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003873.1_3 - 7.9e-11 42.5 0.0 2.8e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain TPR_20 PF14561.6 AAAP01003873.1_3 - 1.5e-08 34.9 14.4 0.032 14.6 0.7 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat Methyltransf_31 PF13847.6 AAAP01003873.1_3 - 4.1e-08 33.2 0.0 7.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AAAP01003873.1_3 - 1.2e-06 28.3 0.1 3.1e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) TPR_10 PF13374.6 AAAP01003873.1_3 - 1.7e-05 24.5 6.2 0.0019 18.0 0.4 9.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003873.1_3 - 0.0002 21.7 70.8 0.14 12.9 5.0 10.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003873.1_3 - 0.0011 18.3 18.9 0.22 10.7 4.2 3.9 1 1 3 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 AAAP01003873.1_3 - 0.0074 15.3 2.2 0.16 10.8 0.0 2.8 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 PrmA PF06325.13 AAAP01003873.1_3 - 0.0075 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Fis1_TPR_C PF14853.6 AAAP01003873.1_3 - 0.033 14.2 2.6 2.3 8.3 0.1 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Barstar PF01337.18 AAAP01003873.1_3 - 0.054 13.5 0.0 19 5.3 0.0 3.4 3 0 0 3 3 3 0 Barstar (barnase inhibitor) MetW PF07021.12 AAAP01003873.1_3 - 0.058 13.0 0.1 0.16 11.5 0.1 1.7 2 0 0 2 2 1 0 Methionine biosynthesis protein MetW Sel1 PF08238.12 AAAP01003873.1_3 - 0.062 14.0 3.1 0.14 12.9 0.5 3.1 2 0 0 2 2 2 0 Sel1 repeat CheR PF01739.18 AAAP01003873.1_3 - 0.068 12.6 0.0 3.2 7.2 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 AAAP01003873.1_3 - 0.11 12.1 0.1 0.33 10.5 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase small domain BTAD PF03704.17 AAAP01003873.1_3 - 0.34 11.3 30.3 3.3 8.1 2.6 4.3 1 1 2 3 3 3 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 AAAP01003873.1_3 - 5.1 7.5 8.9 17 5.9 0.5 4.6 4 1 0 4 4 4 0 Alkyl sulfatase dimerisation Rrf2 PF02082.20 AAAP01003873.1_4 - 1.1e-21 77.0 0.1 1.9e-21 76.2 0.0 1.4 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 AAAP01003873.1_4 - 0.00085 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_Crp_2 PF13545.6 AAAP01003873.1_4 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 AAAP01003873.1_4 - 0.091 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF4423 PF14394.6 AAAP01003873.1_4 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) FMN_red PF03358.15 AAAP01003873.1_5 - 5.5e-13 49.0 0.3 1.3e-12 47.7 0.4 1.7 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 AAAP01003873.1_5 - 4.4e-10 40.0 0.1 6.2e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_2 PF02525.17 AAAP01003873.1_5 - 0.00015 21.6 0.1 0.0014 18.4 0.1 2.1 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 AAAP01003873.1_5 - 0.00018 21.7 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 AAAP01003873.1_5 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Mur_ligase_M PF08245.12 AAAP01003873.1_6 - 1.9e-08 34.5 0.0 3.7e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AAAP01003873.1_6 - 2e-05 24.8 0.0 6.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain MASE3 PF17159.4 AAAP01003873.1_7 - 6.8e-66 222.1 1.1 9.6e-66 221.6 1.1 1.1 1 0 0 1 1 1 1 Membrane-associated sensor domain HATPase_c PF02518.26 AAAP01003873.1_7 - 2.2e-24 86.1 0.0 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003873.1_7 - 3.4e-21 75.6 0.0 6.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003873.1_7 - 1.3e-12 47.7 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003873.1_7 - 3.3e-09 36.9 0.0 5.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 AAAP01003873.1_7 - 2e-07 30.9 0.1 4.2e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003873.1_7 - 0.00092 19.2 0.0 0.0029 17.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain Bax1-I PF01027.20 AAAP01003873.1_7 - 0.001 18.9 3.7 0.001 18.9 3.7 2.0 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 HATPase_c_2 PF13581.6 AAAP01003873.1_7 - 0.011 15.7 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAAP01003873.1_7 - 0.016 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 GHKL domain DUF1772 PF08592.11 AAAP01003873.1_7 - 3.5 7.9 21.1 3.1 8.1 1.1 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Carboxyl_trans PF01039.22 AAAP01003873.1_8 - 1.7e-17 63.2 0.1 2.3e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 AAAP01003873.1_8 - 2.5e-11 43.4 1.3 4.1e-11 42.7 1.3 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain OrfB_Zn_ribbon PF07282.11 AAAP01003873.1_8 - 0.044 13.7 0.5 0.087 12.8 0.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cys_rich_CPCC PF14206.6 AAAP01003873.1_8 - 0.19 11.6 0.5 0.33 10.8 0.5 1.3 1 0 0 1 1 1 0 Cysteine-rich CPCC DNA_RNApol_7kD PF03604.13 AAAP01003873.1_8 - 0.3 10.8 1.1 26 4.6 0.0 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF4379 PF14311.6 AAAP01003873.1_8 - 0.36 11.2 1.1 25 5.3 0.1 2.2 1 1 0 2 2 2 0 Probable Zinc-ribbon domain zinc_ribbon_4 PF13717.6 AAAP01003873.1_8 - 0.43 10.6 1.4 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 AAAP01003873.1_8 - 0.61 9.9 2.7 8.2 6.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.11 AAAP01003873.1_8 - 1.7 8.7 3.1 31 4.6 0.4 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain UPF0547 PF10571.9 AAAP01003873.1_8 - 2.5 8.3 4.8 26 5.0 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 AAAP01003873.1_8 - 2.9 7.4 5.9 41 3.8 0.8 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Trp_syntA PF00290.20 AAAP01003873.1_9 - 2.5e-96 321.5 0.2 2.9e-96 321.3 0.2 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 AAAP01003873.1_9 - 0.00012 21.6 0.3 0.00032 20.2 0.2 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 AAAP01003873.1_9 - 0.0012 18.3 0.2 0.0051 16.3 0.1 2.1 2 1 0 3 3 3 1 PcrB family PALP PF00291.25 AAAP01003873.1_10 - 5.6e-46 157.3 0.4 6.7e-46 157.0 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EAL PF00563.20 AAAP01003873.1_11 - 1e-49 169.2 0.1 2e-49 168.3 0.1 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AAAP01003873.1_11 - 3e-10 40.1 0.0 5.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CBS PF00571.28 AAAP01003873.1_11 - 8.4e-09 35.7 0.7 0.00043 20.7 0.0 3.4 3 0 0 3 3 3 2 CBS domain DUF5380 PF17351.2 AAAP01003873.1_11 - 0.00057 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5380) PseudoU_synth_1 PF01416.20 AAAP01003873.1_11 - 0.096 13.2 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase PAS_3 PF08447.12 AAAP01003873.1_12 - 5.2e-11 42.7 0.0 8.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003873.1_12 - 3.4e-09 36.9 0.0 5.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003873.1_12 - 1.9e-08 34.3 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003873.1_12 - 2.3e-05 24.6 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold Ku PF02735.16 AAAP01003873.1_12 - 0.082 12.6 0.1 5.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Ku70/Ku80 beta-barrel domain NAD_Gly3P_dh_N PF01210.23 AAAP01003873.1_13 - 1.8e-45 154.7 1.3 3.4e-45 153.8 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 AAAP01003873.1_13 - 2.1e-43 148.0 0.7 2.1e-43 148.0 0.7 2.7 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus MCPsignal PF00015.21 AAAP01003873.1_13 - 2.6e-29 102.2 25.9 2.6e-29 102.2 25.9 2.4 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ApbA PF02558.16 AAAP01003873.1_13 - 1.1e-07 31.6 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AAAP01003873.1_13 - 1.8e-05 25.2 0.0 1.8e-05 25.2 0.0 3.4 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAAP01003873.1_13 - 0.00045 20.4 0.0 0.00045 20.4 0.0 3.1 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 AAAP01003873.1_13 - 0.014 15.6 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AAAP01003873.1_13 - 0.068 13.7 0.0 0.39 11.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF948 PF06103.11 AAAP01003873.1_13 - 0.24 11.7 26.2 0.12 12.7 2.7 5.2 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Gly-zipper_OmpA PF13436.6 AAAP01003873.1_14 - 0.0038 17.0 16.4 0.037 13.8 1.2 2.6 2 0 0 2 2 2 2 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 AAAP01003873.1_14 - 0.0089 15.9 24.6 0.081 12.8 24.6 2.3 1 1 2 3 3 3 3 Glycine zipper 2TM domain 17kDa_Anti_2 PF16998.5 AAAP01003873.1_14 - 0.012 15.5 0.3 0.019 14.9 0.3 1.2 1 0 0 1 1 1 0 17 kDa outer membrane surface antigen DUF5061 PF16587.5 AAAP01003873.1_14 - 0.042 13.9 1.8 0.43 10.7 0.1 2.2 2 0 0 2 2 2 0 17 kDa common-antigen outer membrane protein Gly-zipper_Omp PF13488.6 AAAP01003873.1_14 - 0.079 13.0 25.4 0.079 13.0 5.4 2.4 1 1 2 3 3 3 0 Glycine zipper Gly-zipper_YMGG PF13441.6 AAAP01003873.1_14 - 1 9.1 30.2 6 6.7 30.2 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 AAAP01003873.1_14 - 4.9 7.3 24.0 17 5.6 24.0 2.0 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PT-VENN PF04829.13 AAAP01003873.1_14 - 5.2 7.2 8.2 8.2 6.6 0.3 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Bac_DNA_binding PF00216.21 AAAP01003873.1_15 - 2.1e-31 107.9 0.0 2.4e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AAAP01003873.1_15 - 9e-07 29.0 0.0 1e-06 28.9 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 AAAP01003873.1_15 - 0.0066 16.6 0.0 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 AAAP01003873.1_15 - 0.044 13.9 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 AAAP01003873.1_15 - 0.079 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-DNA_bdg PF14848.6 AAAP01003873.1_15 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 DNA-binding domain LapA_dom PF06305.11 AAAP01003873.1_16 - 1.5e-11 43.9 1.2 9e-11 41.4 0.0 1.9 1 1 1 2 2 2 1 Lipopolysaccharide assembly protein A domain YbgT_YccB PF08173.11 AAAP01003873.1_16 - 0.0018 18.4 2.2 0.0018 18.4 2.2 2.0 2 1 0 2 2 2 1 Membrane bound YbgT-like protein OMPdecase PF00215.24 AAAP01003873.1_17 - 4e-39 134.5 0.3 4.5e-39 134.4 0.3 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PRAI PF00697.22 AAAP01003873.1_18 - 4.6e-48 163.6 0.0 5.2e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Phage_lysozyme PF00959.19 AAAP01003873.1_19 - 1.8e-14 54.1 0.0 2.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Polysacc_synt_4 PF04669.13 AAAP01003873.1_19 - 0.19 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis N6_N4_Mtase PF01555.18 AAAP01003873.1_21 - 7.1e-57 192.8 0.0 9.3e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 DNA methylase RAMA PF18755.1 AAAP01003873.1_21 - 7e-16 58.6 0.0 1.2e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated UPF0020 PF01170.18 AAAP01003873.1_21 - 0.0011 18.6 0.0 0.42 10.3 0.0 3.0 3 0 0 3 3 3 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 AAAP01003873.1_21 - 0.0087 15.8 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 AAAP01003873.1_21 - 0.027 15.2 0.0 0.55 11.0 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.15 AAAP01003873.1_21 - 0.027 14.1 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 RNase_HII PF01351.18 AAAP01003873.1_22 - 1.2e-48 165.6 0.0 1.4e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Na_H_Exchanger PF00999.21 AAAP01003873.1_23 - 5.5e-57 193.3 41.9 6.7e-57 193.0 41.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Orai-1 PF07856.12 AAAP01003873.1_23 - 0.018 14.7 1.0 0.018 14.7 1.0 2.5 2 1 0 2 2 2 0 Mediator of CRAC channel activity ATPase_gene1 PF09527.10 AAAP01003873.1_24 - 9.2e-19 67.4 9.1 1.2e-18 67.0 9.1 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Sterol-sensing PF12349.8 AAAP01003873.1_24 - 0.047 13.5 0.0 0.055 13.3 0.0 1.1 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation ATP-synt_A PF00119.20 AAAP01003873.1_25 - 5.1e-57 193.2 28.2 6.1e-57 193.0 28.2 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_C PF00137.21 AAAP01003873.1_26 - 6.2e-13 48.9 10.0 7.7e-13 48.6 10.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_B PF00430.18 AAAP01003873.1_27 - 6e-25 87.9 14.8 7.9e-25 87.5 14.8 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) YMF19 PF02326.15 AAAP01003873.1_27 - 6e-12 46.2 0.0 1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 Plant ATP synthase F0 Mt_ATP-synt_B PF05405.14 AAAP01003873.1_27 - 7.1e-09 35.5 0.5 9e-09 35.2 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NACHT_N PF17100.5 AAAP01003873.1_27 - 0.0028 17.5 2.3 0.0035 17.2 2.3 1.1 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Fun_ATP-synt_8 PF05933.13 AAAP01003873.1_27 - 0.024 14.8 0.9 0.034 14.3 0.9 1.2 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) YbjQ_1 PF01906.17 AAAP01003873.1_27 - 3.2 8.4 6.3 1.4 9.6 1.9 2.1 1 1 1 2 2 2 0 Putative heavy-metal-binding ATP-synt_B PF00430.18 AAAP01003873.1_28 - 7.1e-25 87.6 22.6 9.3e-25 87.2 22.6 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 AAAP01003873.1_28 - 4.9e-12 45.8 2.3 5.8e-12 45.5 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) OmpH PF03938.14 AAAP01003873.1_28 - 0.0014 19.0 10.0 0.0019 18.6 10.0 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF948 PF06103.11 AAAP01003873.1_28 - 0.057 13.7 3.5 1 9.7 3.5 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Actin_micro PF17003.5 AAAP01003873.1_28 - 0.067 12.4 0.5 0.08 12.1 0.5 1.1 1 0 0 1 1 1 0 Putative actin-like family DUF2894 PF11445.8 AAAP01003873.1_28 - 0.087 13.3 9.3 0.11 12.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF2937 PF11157.8 AAAP01003873.1_28 - 0.12 12.1 8.9 0.22 11.2 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) YMF19 PF02326.15 AAAP01003873.1_28 - 0.21 12.4 0.0 0.4 11.5 0.0 1.4 1 1 0 1 1 1 0 Plant ATP synthase F0 TMPIT PF07851.13 AAAP01003873.1_28 - 0.44 9.7 4.9 0.54 9.4 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 AAAP01003873.1_28 - 0.47 10.6 10.4 0.24 11.6 7.5 1.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour dCache_1 PF02743.18 AAAP01003873.1_28 - 2.1 8.0 3.8 0.83 9.4 1.0 1.7 2 0 0 2 2 2 0 Cache domain DUF2203 PF09969.9 AAAP01003873.1_28 - 3.3 8.5 7.9 5.4 7.8 7.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) MutS_IV PF05190.18 AAAP01003873.1_28 - 3.3 8.1 5.6 2.5 8.5 1.1 2.2 1 1 1 2 2 2 0 MutS family domain IV ISG65-75 PF11727.8 AAAP01003873.1_28 - 5.2 6.2 17.5 6.7 5.8 0.7 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein V-ATPase_G_2 PF16999.5 AAAP01003873.1_28 - 6.6 7.2 29.9 56 4.2 29.7 2.3 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit baeRF_family3 PF18845.1 AAAP01003873.1_28 - 7 6.9 12.4 5.3 7.3 1.0 2.3 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Pirin PF02678.16 AAAP01003873.1_29 - 7.8e-37 125.6 2.3 8.1e-37 125.5 0.8 1.7 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 AAAP01003873.1_29 - 1.2e-29 102.3 0.4 9.4e-29 99.4 0.2 2.0 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 AAAP01003873.1_29 - 0.002 17.8 0.4 0.38 10.5 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Pirin_C PF05726.13 AAAP01003873.1_29 - 0.0091 16.3 0.0 0.15 12.4 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain DPPIV_rep PF18811.1 AAAP01003873.1_29 - 0.1 12.5 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region HlyD_D23 PF16576.5 AAAP01003873.1_30 - 6.3e-23 81.1 2.3 1.2e-21 77.0 2.3 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003873.1_30 - 1.2e-21 77.4 4.9 8.1e-18 65.1 0.2 2.6 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AAAP01003873.1_30 - 1.3e-16 60.1 10.1 5.2e-12 45.4 0.4 3.3 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD PF00529.20 AAAP01003873.1_30 - 4.7e-12 45.6 0.0 7.6e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AAAP01003873.1_30 - 0.0013 18.5 0.2 2.6 8.0 0.0 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme SIS PF01380.22 AAAP01003873.1_30 - 0.018 14.9 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 SIS domain YqfD PF06898.11 AAAP01003873.1_30 - 0.067 12.0 1.2 1.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD FliJ PF02050.16 AAAP01003873.1_30 - 1.5 9.1 7.4 0.35 11.1 0.7 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.16 AAAP01003873.1_31 - 2e-45 155.3 42.1 2e-45 155.3 42.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AAAP01003873.1_31 - 0.95 8.3 27.5 0.086 11.7 4.0 2.3 2 0 0 2 2 2 0 MFS_1 like family UL42 PF17638.2 AAAP01003873.1_31 - 2.3 8.2 4.6 0.51 10.3 0.5 2.0 2 0 0 2 2 2 0 HCMV UL42 GGDEF PF00990.21 AAAP01003873.1_32 - 3.1e-52 176.6 0.0 4.6e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AAAP01003873.1_32 - 1.4e-09 38.1 0.0 2.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003873.1_32 - 4.2e-08 33.2 0.0 1e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003873.1_32 - 1.4e-07 31.7 0.3 1.8e-06 28.1 0.3 2.3 1 1 0 1 1 1 1 PAS fold MLTR_LBD PF17765.1 AAAP01003873.1_32 - 0.012 15.8 0.6 0.062 13.4 0.1 2.4 2 1 1 3 3 3 0 MmyB-like transcription regulator ligand binding domain PAS_8 PF13188.7 AAAP01003873.1_32 - 0.11 12.6 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.12 AAAP01003873.1_32 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold Glyco_hydro_85 PF03644.13 AAAP01003873.1_33 - 0.036 13.5 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 NUDIX_4 PF14815.6 AAAP01003873.1_34 - 6.1e-25 87.4 0.2 1.6e-24 86.0 0.2 1.8 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 AAAP01003873.1_34 - 2.4e-17 63.3 0.0 4.4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AAAP01003873.1_34 - 2.2e-05 24.1 0.0 8.6e-05 22.2 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AAAP01003873.1_34 - 0.35 11.3 8.1 0.75 10.2 8.1 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DciA PF05258.12 AAAP01003873.1_35 - 1.4e-18 67.0 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA DUF3328 PF11807.8 AAAP01003873.1_36 - 0.12 12.2 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Thioredoxin_4 PF13462.6 AAAP01003873.1_37 - 9.5e-43 146.2 0.0 1.2e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 AAAP01003873.1_37 - 8.5e-09 35.5 0.0 0.00015 21.6 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 AAAP01003873.1_37 - 6.7e-05 23.3 0.2 0.00095 19.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 AAAP01003873.1_37 - 0.0011 19.0 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_12 PF18400.1 AAAP01003873.1_37 - 0.02 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain SMC_N PF02463.19 AAAP01003873.1_38 - 9.6e-57 191.9 0.0 1.3e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AAAP01003873.1_38 - 8.7e-11 42.7 9.2 8.7e-11 42.7 9.2 4.4 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.6 AAAP01003873.1_38 - 4e-10 40.0 0.2 4.5e-06 26.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AAAP01003873.1_38 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AAAP01003873.1_38 - 2.9e-05 24.6 3.9 0.021 15.4 0.0 4.3 4 0 0 4 4 4 2 ABC transporter AAA_29 PF13555.6 AAAP01003873.1_38 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vac_Fusion PF02346.16 AAAP01003873.1_38 - 7.9 6.2 8.9 12 5.6 0.2 3.9 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 PAS_3 PF08447.12 AAAP01003873.1_39 - 4.9e-27 94.0 0.0 1.9e-14 53.7 0.0 2.9 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 AAAP01003873.1_39 - 9.7e-26 90.5 0.0 2.2e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAAP01003873.1_39 - 1.5e-15 57.6 0.0 3.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Cache domain HisKA PF00512.25 AAAP01003873.1_39 - 1.5e-11 44.1 0.2 6.2e-11 42.2 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AAAP01003873.1_39 - 2.9e-07 30.7 0.6 0.00015 22.0 0.1 3.0 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01003873.1_39 - 4.7e-06 26.6 0.0 0.0059 16.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold HATPase_c_5 PF14501.6 AAAP01003873.1_39 - 8.9e-05 22.3 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_9 PF13426.7 AAAP01003873.1_39 - 0.055 13.7 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 PAS domain Pro_Al_protease PF02983.14 AAAP01003873.1_39 - 0.071 13.2 0.8 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Alpha-lytic protease prodomain FTA2 PF13095.6 AAAP01003873.1_39 - 0.19 11.3 0.0 0.9 9.1 0.0 2.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Arginosuc_synth PF00764.19 AAAP01003873.1_40 - 3.6e-148 494.0 0.0 4.6e-148 493.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 AAAP01003873.1_40 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AAAP01003873.1_40 - 0.0058 16.3 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Radical_SAM PF04055.21 AAAP01003873.1_41 - 1.4e-14 54.8 0.1 3.1e-14 53.7 0.1 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAAP01003873.1_41 - 0.19 11.8 0.7 0.87 9.7 0.7 2.0 1 1 0 1 1 1 0 4Fe-4S single cluster domain TetR_N PF00440.23 AAAP01003873.1_42 - 7.3e-17 60.9 0.9 1.3e-16 60.0 0.9 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AAAP01003873.1_42 - 0.0034 17.5 1.7 0.0034 17.5 1.7 2.6 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain AAA_2 PF07724.14 AAAP01003873.1_43 - 1.5e-49 168.4 0.0 2e-46 158.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AAAP01003873.1_43 - 1.2e-28 99.1 1.9 3.5e-28 97.6 1.9 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AAAP01003873.1_43 - 2.8e-25 89.3 0.1 9.7e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AAAP01003873.1_43 - 7e-25 86.9 0.0 2.8e-24 85.0 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AAAP01003873.1_43 - 5e-20 71.9 0.0 2.2e-13 50.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AAAP01003873.1_43 - 4e-12 46.1 0.7 1.2e-11 44.6 0.7 1.9 1 0 0 1 1 1 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AAAP01003873.1_43 - 4.8e-12 46.6 2.9 0.00025 21.4 0.0 4.0 4 1 0 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 AAAP01003873.1_43 - 1.1e-09 38.2 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 AAAP01003873.1_43 - 1.2e-08 34.9 1.0 0.018 14.8 0.0 4.4 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AAAP01003873.1_43 - 3.8e-07 30.5 1.7 0.034 14.4 1.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AAAP01003873.1_43 - 1.1e-06 29.2 0.0 0.027 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AAAP01003873.1_43 - 1.8e-06 27.5 0.0 0.056 12.8 0.0 3.4 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AAAP01003873.1_43 - 1.9e-06 27.8 0.1 0.00031 20.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AAAP01003873.1_43 - 1.4e-05 24.6 0.0 0.039 13.4 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 AAAP01003873.1_43 - 7.7e-05 22.7 0.0 0.45 10.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AAAP01003873.1_43 - 0.0002 20.9 0.0 0.97 8.9 0.0 3.0 4 0 0 4 4 3 2 P-loop containing dynein motor region RNA_helicase PF00910.22 AAAP01003873.1_43 - 0.00028 21.2 0.0 0.81 10.1 0.0 3.2 3 0 0 3 3 3 1 RNA helicase TIP49 PF06068.13 AAAP01003873.1_43 - 0.00035 19.9 0.2 0.84 8.8 0.0 2.5 3 0 0 3 3 2 2 TIP49 P-loop domain TsaE PF02367.17 AAAP01003873.1_43 - 0.00052 20.0 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 AAAP01003873.1_43 - 0.00056 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region IstB_IS21 PF01695.17 AAAP01003873.1_43 - 0.00097 18.9 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Torsin PF06309.11 AAAP01003873.1_43 - 0.0013 18.8 0.0 0.0042 17.2 0.0 1.8 2 0 0 2 2 1 1 Torsin AAA_33 PF13671.6 AAAP01003873.1_43 - 0.0035 17.5 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 AAAP01003873.1_43 - 0.0082 15.9 0.1 0.36 10.6 0.0 3.3 5 0 0 5 5 4 1 DNA polymerase III, delta subunit ResIII PF04851.15 AAAP01003873.1_43 - 0.0096 15.9 0.0 0.56 10.2 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AAAP01003873.1_43 - 0.013 15.1 0.7 1.3 8.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 AAAP01003873.1_43 - 0.021 14.8 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 AAAP01003873.1_43 - 0.022 14.7 0.0 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 AAAP01003873.1_43 - 0.022 14.9 0.0 13 5.9 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 AAAP01003873.1_43 - 0.027 14.7 0.0 3 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 AAAP01003873.1_43 - 0.045 13.8 0.0 37 4.4 0.0 3.7 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AAAP01003873.1_43 - 0.05 12.9 0.0 5.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 AAAP01003873.1_43 - 0.069 13.6 0.0 5.4 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 AAAP01003873.1_43 - 0.1 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Isopentenyl transferase NTPase_1 PF03266.15 AAAP01003873.1_43 - 0.14 12.0 0.2 56 3.6 0.0 3.7 4 0 0 4 4 4 0 NTPase ClpS PF02617.17 AAAP01003873.1_44 - 6e-36 122.1 0.5 7.3e-36 121.8 0.5 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Phasin_2 PF09361.10 AAAP01003873.1_45 - 1.6e-20 73.2 0.4 2.2e-20 72.8 0.4 1.2 1 0 0 1 1 1 1 Phasin protein Cauli_AT PF03233.13 AAAP01003873.1_45 - 0.041 13.8 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Aphid transmission protein DUF4031 PF13223.6 AAAP01003873.1_46 - 1 9.6 3.6 19 5.6 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4031) Activator-TraM PF11657.8 AAAP01003873.1_46 - 1.1 9.1 10.1 4.2 7.2 1.7 2.3 1 1 1 2 2 2 0 Transcriptional activator TraM DUF1896 PF08989.10 AAAP01003873.1_46 - 7.4 6.7 5.1 21 5.2 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF1896) MCPsignal PF00015.21 AAAP01003873.1_47 - 2.2e-33 115.5 28.4 2.2e-33 115.5 28.4 3.9 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Hemerythrin PF01814.23 AAAP01003873.1_47 - 6.3e-10 39.8 3.5 6.3e-10 39.8 3.5 4.2 3 1 1 4 4 4 1 Hemerythrin HHE cation binding domain HAMP PF00672.25 AAAP01003873.1_47 - 7.2e-09 35.9 3.9 3.8e-08 33.6 0.0 4.2 4 0 0 4 4 4 1 HAMP domain HBM PF16591.5 AAAP01003873.1_47 - 8.2e-07 28.7 13.6 8.2e-07 28.7 13.6 4.3 2 1 1 4 4 4 1 Helical bimodular sensor domain DUF1664 PF07889.12 AAAP01003873.1_47 - 0.0057 16.7 22.9 0.11 12.5 2.5 4.9 2 2 1 3 3 3 2 Protein of unknown function (DUF1664) Dor1 PF04124.12 AAAP01003873.1_47 - 0.2 10.3 13.5 0.007 15.1 3.0 3.2 2 1 0 3 3 3 0 Dor1-like family EB_dh PF09459.10 AAAP01003873.1_47 - 1.9 8.4 6.4 2.7 7.9 2.6 2.2 1 1 1 2 2 2 0 Ethylbenzene dehydrogenase Laminin_II PF06009.12 AAAP01003873.1_47 - 2.1 8.4 33.4 3.3 7.7 8.7 5.2 2 2 4 6 6 6 0 Laminin Domain II TACC_C PF05010.14 AAAP01003873.1_47 - 2.3 8.0 19.0 0.18 11.6 0.5 4.0 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CDC37_N PF03234.14 AAAP01003873.1_47 - 3.7 8.5 19.7 0.036 15.0 4.1 4.5 4 1 0 5 5 5 0 Cdc37 N terminal kinase binding Peptidase_S11 PF00768.20 AAAP01003873.1_49 - 5.1e-57 193.1 0.0 6.9e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AAAP01003873.1_49 - 2.4e-10 40.4 0.1 3.6e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family SPOR PF05036.13 AAAP01003873.1_49 - 2e-06 28.1 0.6 2e-06 28.1 0.6 2.2 2 0 0 2 2 2 1 Sporulation related domain GGACT PF06094.12 AAAP01003873.1_50 - 1.8e-16 60.8 0.0 2.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GAF_2 PF13185.6 AAAP01003873.1_51 - 0.0004 20.7 0.0 0.00078 19.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 AAAP01003873.1_51 - 0.0036 17.9 0.0 0.0048 17.5 0.0 1.3 1 1 0 1 1 1 1 GAF domain cNMP_binding PF00027.29 AAAP01003873.1_52 - 4e-16 58.8 0.0 6.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003873.1_52 - 4.6e-11 42.5 0.0 1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 AAAP01003873.1_52 - 0.00016 21.2 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Flp_Fap PF04964.14 AAAP01003873.1_53 - 3.9e-16 58.6 0.3 6.8e-16 57.8 0.2 1.5 1 1 0 1 1 1 1 Flp/Fap pilin component Flp_Fap PF04964.14 AAAP01003873.1_54 - 4.8e-16 58.3 0.5 6.2e-16 58.0 0.1 1.4 2 0 0 2 2 2 1 Flp/Fap pilin component Peptidase_A24 PF01478.18 AAAP01003873.1_55 - 5.5e-09 36.4 10.9 8.2e-09 35.8 10.9 1.2 1 0 0 1 1 1 1 Type IV leader peptidase family RcpC PF16976.5 AAAP01003873.1_56 - 1.8e-27 95.7 2.0 8.1e-27 93.6 2.0 2.0 1 1 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB SAF PF08666.12 AAAP01003873.1_56 - 6.9e-09 36.2 0.2 5.3e-08 33.4 0.1 2.5 2 0 0 2 2 2 1 SAF domain Secretin PF00263.21 AAAP01003873.1_57 - 1.1e-36 126.0 0.3 1.8e-36 125.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein T2SS-T3SS_pil_N PF13629.6 AAAP01003873.1_57 - 7.6e-19 67.2 1.8 7.6e-19 67.2 1.8 1.9 2 0 0 2 2 2 1 Pilus formation protein N terminal region BON PF04972.17 AAAP01003873.1_57 - 1.5e-05 25.2 2.9 1.5e-05 25.2 0.7 2.1 1 1 1 2 2 2 1 BON domain Pilus_CpaD PF09476.10 AAAP01003873.1_58 - 5.2e-44 150.4 0.1 6.2e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) CBP_BcsQ PF06564.12 AAAP01003873.1_59 - 1.3e-08 34.7 0.6 2.3e-08 33.8 0.6 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 AAAP01003873.1_59 - 2.6e-07 30.7 0.0 2.6e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01003873.1_59 - 2e-05 24.7 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 AAAP01003873.1_59 - 3.9e-05 23.2 0.0 0.00023 20.7 0.0 2.0 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 AAAP01003873.1_59 - 0.00045 19.7 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AAAP01003873.1_59 - 0.018 14.3 0.2 0.81 8.9 0.2 2.8 2 1 0 2 2 2 0 ATPase MipZ AAA_25 PF13481.6 AAAP01003873.1_59 - 0.05 13.2 3.6 2.7 7.5 1.1 2.6 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 AAAP01003873.1_60 - 9e-81 270.9 0.4 1.4e-80 270.3 0.4 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAAP01003873.1_60 - 0.00031 21.2 0.0 0.00078 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AAAP01003873.1_60 - 0.00034 21.1 0.0 0.0011 19.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.21 AAAP01003873.1_60 - 0.00083 18.8 0.0 0.0018 17.7 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AAAP01003873.1_60 - 0.0011 19.6 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AAAP01003873.1_60 - 0.0025 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 AAAP01003873.1_60 - 0.0029 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 AAAP01003873.1_60 - 0.0054 16.1 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.6 AAAP01003873.1_60 - 0.0057 17.0 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AAAP01003873.1_60 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AAAP01003873.1_60 - 0.021 14.4 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AAAP01003873.1_60 - 0.026 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AAAP01003873.1_60 - 0.032 14.5 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AAAP01003873.1_60 - 0.045 13.4 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 AAAP01003873.1_60 - 0.074 13.2 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 AAAP01003873.1_60 - 0.075 12.4 0.1 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.9 AAAP01003873.1_60 - 0.076 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.18 AAAP01003873.1_60 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 AAAP01003873.1_60 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 AAAP01003873.1_60 - 0.11 11.8 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.20 AAAP01003873.1_60 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit UvrD-helicase PF00580.21 AAAP01003873.1_60 - 0.14 11.7 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 AAAP01003873.1_60 - 0.19 11.3 1.1 1.5 8.4 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain T2SSF PF00482.23 AAAP01003873.1_61 - 1.9e-19 69.8 3.6 1.9e-19 69.8 3.6 1.8 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F T2SSF PF00482.23 AAAP01003873.1_62 - 1.5e-18 66.9 1.5 1.5e-18 66.9 1.5 2.0 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F TPR_2 PF07719.17 AAAP01003873.1_64 - 1.5e-09 37.2 13.9 4.1e-05 23.4 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003873.1_64 - 2e-09 37.2 5.2 7.1e-05 22.9 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003873.1_64 - 3.7e-09 36.1 4.5 1.2e-05 24.9 1.0 3.5 1 1 2 3 3 3 2 TPR repeat TPR_19 PF14559.6 AAAP01003873.1_64 - 1.1e-08 35.4 23.6 2.1e-05 24.9 2.7 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003873.1_64 - 2.7e-08 33.3 1.0 0.0041 16.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003873.1_64 - 6.1e-08 33.2 18.9 6.3e-05 23.5 8.4 4.6 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003873.1_64 - 5.7e-06 26.7 31.2 0.0032 18.2 0.5 5.7 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003873.1_64 - 2.1e-05 24.7 27.4 0.00093 19.4 3.9 4.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003873.1_64 - 7.2e-05 22.7 0.5 0.0034 17.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AAAP01003873.1_64 - 0.0039 17.1 2.8 0.5 10.3 0.7 2.7 1 1 1 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 AAAP01003873.1_64 - 0.0062 16.7 1.8 0.0062 16.7 1.8 3.6 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003873.1_64 - 0.0088 16.4 12.2 0.53 10.6 0.2 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003873.1_64 - 0.017 15.0 24.6 0.2 11.5 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 AAAP01003873.1_64 - 0.11 11.4 0.3 0.61 8.9 0.1 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 AAAP01003873.1_64 - 0.52 10.5 0.1 0.52 10.5 0.1 3.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003873.1_64 - 0.69 10.7 16.0 5.9 7.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat T2SS-T3SS_pil_N PF13629.6 AAAP01003873.1_65 - 1.9e-19 69.2 1.3 2.8e-19 68.6 1.3 1.3 1 0 0 1 1 1 1 Pilus formation protein N terminal region Tad PF13400.6 AAAP01003873.1_66 - 2.1e-09 37.5 5.1 2.1e-09 37.5 5.1 2.3 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like TadE PF07811.12 AAAP01003873.1_67 - 2.8e-14 53.1 1.3 4.7e-14 52.4 1.3 1.4 1 0 0 1 1 1 1 TadE-like protein Tad PF13400.6 AAAP01003873.1_67 - 0.012 15.9 2.3 0.021 15.1 2.3 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF983 PF06170.12 AAAP01003873.1_67 - 0.21 12.0 1.4 0.21 12.0 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TadE PF07811.12 AAAP01003873.1_68 - 3.7e-11 43.1 2.8 6.5e-11 42.3 2.8 1.4 1 0 0 1 1 1 1 TadE-like protein Flp_Fap PF04964.14 AAAP01003873.1_68 - 0.0005 19.8 0.4 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Flp/Fap pilin component Tad PF13400.6 AAAP01003873.1_68 - 0.00098 19.4 3.4 0.00098 19.4 3.4 2.2 3 0 0 3 3 3 1 Putative Flp pilus-assembly TadE/G-like TadF PF16964.5 AAAP01003873.1_68 - 0.2 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative tight adherence pilin protein F HpcH_HpaI PF03328.14 AAAP01003873.1_69 - 1.5e-27 96.2 0.0 5.8e-27 94.3 0.0 1.9 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AAAP01003873.1_69 - 0.0035 16.6 0.0 0.67 9.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Glyoxalase_3 PF13468.6 AAAP01003873.1_70 - 2.1e-39 135.4 0.8 8.6e-37 126.9 0.2 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AAAP01003873.1_70 - 6.3e-08 32.9 0.1 2.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4224 PF13986.6 AAAP01003873.1_70 - 0.00023 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4224) Glyoxalase PF00903.25 AAAP01003873.1_70 - 0.00073 19.7 0.0 0.006 16.8 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PDH PF02153.17 AAAP01003873.1_71 - 5.7e-76 254.9 0.0 6.6e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 AAAP01003873.1_71 - 3.6e-07 30.7 0.0 7.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AAAP01003873.1_71 - 5.2e-07 30.0 0.0 2.7e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AAAP01003873.1_71 - 0.0039 16.6 0.0 0.0084 15.5 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAAP01003873.1_71 - 0.03 15.1 0.1 0.096 13.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 AAAP01003873.1_71 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Aminotran_1_2 PF00155.21 AAAP01003873.1_72 - 2.9e-47 161.6 0.0 4.2e-47 161.1 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAAP01003873.1_72 - 7.3e-06 25.2 0.0 2.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AAAP01003873.1_72 - 4.2e-05 23.0 0.0 5.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAAP01003873.1_72 - 0.032 12.8 0.0 0.043 12.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CM_2 PF01817.21 AAAP01003873.1_73 - 1.3e-16 60.7 0.4 2.2e-16 60.0 0.4 1.4 1 0 0 1 1 1 1 Chorismate mutase type II Abhydrolase_1 PF00561.20 AAAP01003873.1_74 - 1.3e-33 116.7 0.2 1.7e-33 116.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003873.1_74 - 6.3e-05 23.7 1.0 8.5e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AAAP01003873.1_74 - 0.0003 20.1 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 AAAP01003873.1_74 - 0.044 13.4 0.0 0.093 12.4 0.0 1.5 2 0 0 2 2 2 0 Putative esterase MetW PF07021.12 AAAP01003873.1_75 - 5.1e-84 280.7 0.0 5.8e-84 280.5 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 AAAP01003873.1_75 - 7.9e-10 38.8 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003873.1_75 - 3.3e-08 34.1 0.0 5.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003873.1_75 - 7.5e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003873.1_75 - 2.2e-07 31.5 0.0 3.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003873.1_75 - 1.1e-05 26.0 0.1 2.5e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01003873.1_75 - 0.0028 17.0 0.1 0.0038 16.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 AAAP01003873.1_75 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003873.1_75 - 0.22 11.1 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain sCache_2 PF17200.4 AAAP01003873.1_76 - 1.2e-36 125.9 0.4 5.6e-36 123.7 0.0 2.3 2 0 0 2 2 2 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003873.1_76 - 2.8e-33 115.4 0.0 2.8e-33 115.4 0.0 2.7 3 0 0 3 3 3 1 Cache domain MCPsignal PF00015.21 AAAP01003873.1_76 - 2.4e-28 99.1 30.9 2.4e-28 99.1 30.9 3.0 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Cache_3-Cache_2 PF17201.4 AAAP01003873.1_76 - 1.1e-10 41.2 0.0 1.1e-10 41.2 0.0 3.1 3 1 0 3 3 3 1 Cache 3/Cache 2 fusion domain HAMP PF00672.25 AAAP01003873.1_76 - 3.5e-08 33.7 2.3 1.6e-07 31.6 0.1 3.4 3 0 0 3 3 3 1 HAMP domain DUF4756 PF15948.5 AAAP01003873.1_76 - 0.021 14.7 1.1 0.021 14.7 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) DUF1664 PF07889.12 AAAP01003873.1_76 - 0.09 12.8 20.8 1.2 9.1 2.4 4.6 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 AAAP01003873.1_76 - 0.37 9.4 16.7 0.17 10.5 13.9 1.7 1 1 1 2 2 2 0 AAA domain Syntaxin_2 PF14523.6 AAAP01003873.1_76 - 0.72 10.3 3.8 1.7 9.0 0.2 2.9 2 2 0 2 2 2 0 Syntaxin-like protein IFT46_B_C PF12317.8 AAAP01003873.1_76 - 0.84 9.3 5.4 1.6 8.4 0.6 2.8 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal V_ATPase_I PF01496.19 AAAP01003873.1_76 - 2.2 6.1 13.9 5 4.9 13.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5312 PF17239.2 AAAP01003873.1_76 - 2.3 6.5 7.3 1.8 6.8 1.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5312) PPK2 PF03976.14 AAAP01003873.1_77 - 1.2e-136 453.6 10.0 4.1e-84 281.6 2.6 2.0 2 0 0 2 2 2 2 Polyphosphate kinase 2 (PPK2) Thymidylate_kin PF02223.17 AAAP01003873.1_77 - 0.00078 19.2 0.0 0.77 9.4 0.0 3.1 3 0 0 3 3 3 2 Thymidylate kinase Zeta_toxin PF06414.12 AAAP01003873.1_77 - 0.0069 15.7 0.0 0.12 11.6 0.0 2.7 2 1 1 3 3 3 1 Zeta toxin DUF190 PF02641.15 AAAP01003873.1_77 - 0.1 13.0 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 AAA_18 PF13238.6 AAAP01003873.1_77 - 0.14 12.7 0.0 5.5 7.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain Npun_R1517 PF18068.1 AAAP01003873.1_78 - 0.072 13.4 0.0 0.089 13.1 0.0 1.1 1 0 0 1 1 1 0 Npun R1517 ParE_toxin PF05016.15 AAAP01003873.1_79 - 2.1e-11 44.2 0.0 2.4e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE MFS_1 PF07690.16 AAAP01003873.1_80 - 1.5e-29 103.0 66.2 2.9e-26 92.2 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 AAAP01003873.1_80 - 6.3e-10 38.9 43.2 8.8e-10 38.4 43.2 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 AAAP01003873.1_80 - 1.1e-06 27.4 31.7 0.00016 20.4 7.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 AAAP01003873.1_80 - 3.1 6.0 7.8 0.31 9.3 0.5 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Hemerythrin PF01814.23 AAAP01003873.1_81 - 0.00012 22.7 4.3 0.00018 22.1 4.3 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF3228 PF11539.8 AAAP01003873.1_81 - 0.0063 16.0 0.0 0.033 13.7 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3228) Pyr_redox_2 PF07992.14 AAAP01003873.1_82 - 4e-65 220.0 4.8 6.2e-65 219.3 4.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AAAP01003873.1_82 - 7.7e-39 132.4 0.2 7.7e-39 132.4 0.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AAAP01003873.1_82 - 6.8e-21 74.6 1.7 1.7e-20 73.4 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003873.1_82 - 2.5e-09 36.8 0.0 4.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AAAP01003873.1_82 - 3.7e-06 26.3 0.5 0.0017 17.6 0.1 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 AAAP01003873.1_82 - 0.0034 16.7 0.5 0.013 14.8 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AAAP01003873.1_82 - 0.008 16.1 0.3 0.024 14.5 0.3 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 AAAP01003873.1_82 - 0.0091 15.4 8.7 0.03 13.7 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.24 AAAP01003873.1_82 - 0.017 14.7 12.3 0.11 12.0 0.1 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 AAAP01003873.1_82 - 0.034 13.2 9.9 0.58 9.2 4.0 2.9 2 1 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.15 AAAP01003873.1_82 - 0.053 12.1 1.0 1 7.9 0.0 2.2 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 AAAP01003873.1_82 - 0.065 12.3 18.0 0.89 8.6 0.2 4.5 3 1 2 5 5 5 0 FAD binding domain NAD_binding_8 PF13450.6 AAAP01003873.1_82 - 0.07 13.4 3.1 3.1 8.1 0.1 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AAAP01003873.1_82 - 0.074 13.5 3.1 1.3 9.5 0.1 3.3 3 1 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 AAAP01003873.1_82 - 0.16 10.7 7.9 2.5 6.7 0.1 3.9 3 1 1 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 AAAP01003873.1_82 - 0.59 9.3 7.7 7.3 5.7 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain Hydrolase PF00702.26 AAAP01003874.1_1 - 3.1e-32 112.6 1.5 3.1e-32 112.6 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 AAAP01003874.1_1 - 4e-30 104.7 3.3 4e-30 104.7 3.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 AAAP01003874.1_1 - 0.00027 21.4 0.1 0.0018 18.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AAAP01003874.1_1 - 0.0013 18.5 0.4 0.0026 17.5 0.2 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EMP70 PF02990.16 AAAP01003874.1_1 - 0.49 9.0 1.2 1 7.9 1.2 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 KdpC PF02669.15 AAAP01003874.1_2 - 2.5e-69 232.7 0.0 2.9e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain KdpD PF02702.17 AAAP01003874.1_3 - 3.3e-68 229.3 0.2 5.4e-68 228.6 0.2 1.4 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 AAAP01003874.1_3 - 4.3e-29 100.4 15.0 9e-29 99.4 15.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AAAP01003874.1_3 - 1.9e-24 86.3 0.0 4.2e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003874.1_3 - 2.1e-14 53.3 2.6 4.2e-13 49.1 0.9 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 AAAP01003874.1_3 - 2e-13 50.8 0.1 5.1e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 GAF domain Usp PF00582.26 AAAP01003874.1_3 - 6.9e-09 36.3 6.1 8.6e-09 36.0 1.9 3.1 2 1 0 2 2 2 1 Universal stress protein family GAF_2 PF13185.6 AAAP01003874.1_3 - 5.6e-08 33.2 0.4 4.5e-07 30.2 0.1 2.8 2 1 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.6 AAAP01003874.1_3 - 0.024 14.6 0.0 0.095 12.7 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AAAP01003874.1_4 - 1.6e-27 95.9 0.2 6.7e-27 93.9 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HD_5 PF13487.6 AAAP01003874.1_4 - 1.3e-18 67.0 0.1 4.4e-17 62.1 0.0 2.8 3 0 0 3 3 3 1 HD domain HD PF01966.22 AAAP01003874.1_4 - 9.9e-17 61.3 0.0 2.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 HD domain 2-oxoacid_dh PF00198.23 AAAP01003874.1_4 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Response_reg PF00072.24 AAAP01003874.1_5 - 2e-19 69.8 0.0 2.3e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 AAAP01003874.1_6 - 5.7e-48 161.7 6.1 5.4e-28 97.4 2.2 2.7 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.7 AAAP01003874.1_6 - 8.1e-35 119.2 0.0 1e-11 45.0 0.0 3.6 3 0 0 3 3 3 3 PAS domain HATPase_c PF02518.26 AAAP01003874.1_6 - 4e-28 98.2 0.1 1.2e-27 96.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01003874.1_6 - 3.2e-25 88.3 0.0 6.4e-09 35.8 0.0 3.6 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 AAAP01003874.1_6 - 2.9e-21 75.3 0.0 2.9e-21 75.3 0.0 3.7 4 0 0 4 4 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003874.1_6 - 7.2e-17 61.0 0.1 1.9e-06 27.7 0.0 4.0 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AAAP01003874.1_6 - 7.6e-17 61.6 3.5 1.4e-06 28.6 0.0 4.3 4 1 0 4 4 4 3 PAS fold GAF_2 PF13185.6 AAAP01003874.1_6 - 7.6e-10 39.2 0.4 5.7e-09 36.4 0.1 2.7 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 AAAP01003874.1_6 - 3.8e-09 36.7 0.0 0.0001 22.5 0.0 3.7 3 0 0 3 3 3 1 PAS fold HAMP PF00672.25 AAAP01003874.1_6 - 3.4e-07 30.5 2.2 1.1e-06 28.9 1.3 2.6 2 0 0 2 2 2 1 HAMP domain Hpt PF01627.23 AAAP01003874.1_6 - 7.2e-07 29.4 1.5 7.2e-07 29.4 1.5 2.8 2 0 0 2 2 1 1 Hpt domain PAS_7 PF12860.7 AAAP01003874.1_6 - 0.084 13.0 0.0 46 4.2 0.0 4.3 3 2 0 3 3 3 0 PAS fold PRT_C PF08372.10 AAAP01003874.1_6 - 0.089 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal GAF PF01590.26 AAAP01003874.1_6 - 0.098 13.3 0.0 0.47 11.1 0.0 2.2 2 0 0 2 2 1 0 GAF domain Tankyrase_bdg_C PF15327.6 AAAP01003874.1_6 - 0.12 12.9 0.1 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain CheR PF01739.18 AAAP01003874.1_7 - 2.3e-49 167.5 0.0 3.5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheB_methylest PF01339.17 AAAP01003874.1_7 - 9.3e-45 152.4 0.1 1.7e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 CheB methylesterase CheR_N PF03705.15 AAAP01003874.1_7 - 3.7e-14 52.2 0.1 7e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 AAAP01003874.1_7 - 0.0014 19.3 0.0 0.07 13.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003874.1_7 - 0.023 15.4 0.0 1.8 9.3 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain Response_reg PF00072.24 AAAP01003874.1_8 - 7.3e-46 155.0 5.8 1.9e-24 86.0 0.8 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 AAAP01003874.1_8 - 4e-30 104.6 0.1 7.1e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003874.1_8 - 3.3e-21 75.1 0.1 1.2e-20 73.3 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAAP01003874.1_8 - 4.9e-11 42.7 1.4 4.9e-11 42.7 1.4 2.7 2 0 0 2 2 2 1 Hpt domain HATPase_c_3 PF13589.6 AAAP01003874.1_8 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRCT_3 PF18428.1 AAAP01003874.1_8 - 0.14 12.2 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PAS PF00989.25 AAAP01003874.1_9 - 1.4e-28 99.2 0.0 8.2e-15 54.8 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AAAP01003874.1_9 - 8.7e-26 90.2 0.0 9.1e-13 48.4 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AAAP01003874.1_9 - 2e-24 86.0 1.8 7.3e-14 52.0 0.1 3.3 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AAAP01003874.1_9 - 3.1e-18 65.4 0.0 3e-10 39.9 0.0 4.3 4 0 0 4 4 4 2 PAS domain 4HB_MCP_1 PF12729.7 AAAP01003874.1_9 - 1.5e-17 63.7 3.1 2.8e-17 62.9 3.1 1.4 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction GAF_2 PF13185.6 AAAP01003874.1_9 - 3.8e-17 62.9 0.5 4.1e-16 59.5 0.1 2.8 3 0 0 3 3 3 1 GAF domain PAS_7 PF12860.7 AAAP01003874.1_9 - 8.6e-10 38.8 0.3 0.0012 19.0 0.0 3.8 3 0 0 3 3 3 2 PAS fold GAF PF01590.26 AAAP01003874.1_9 - 1.6e-09 38.5 0.0 3.3e-06 27.8 0.0 2.9 2 0 0 2 2 2 2 GAF domain PAS_3 PF08447.12 AAAP01003874.1_9 - 1.1e-05 25.6 0.0 0.054 13.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold HAMP PF00672.25 AAAP01003874.1_9 - 3e-05 24.3 0.0 8.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 HAMP domain TarH PF02203.15 AAAP01003874.1_9 - 0.0006 19.8 6.4 0.0006 19.8 6.4 2.4 2 1 0 2 2 1 1 Tar ligand binding domain homologue CBP_BcsR PF10945.8 AAAP01003874.1_9 - 0.03 13.8 1.0 7.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR DUF4375 PF14300.6 AAAP01003874.1_9 - 0.094 13.0 2.3 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) FAD-SLDH PF12318.8 AAAP01003874.1_9 - 1.3 9.0 4.9 1.1 9.3 0.1 3.0 3 1 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Synaptobrevin PF00957.21 AAAP01003874.1_9 - 2.5 7.9 4.8 1.6 8.5 1.0 2.6 2 0 0 2 2 2 0 Synaptobrevin XhlA PF10779.9 AAAP01003874.1_9 - 5.8 7.2 5.5 3.1 8.1 2.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA PocR PF10114.9 AAAP01003874.1_10 - 1.6e-40 138.6 0.0 8.3e-40 136.2 0.0 2.1 2 0 0 2 2 2 1 Sensory domain found in PocR GAF_2 PF13185.6 AAAP01003874.1_10 - 2.1e-12 47.5 2.5 5.1e-12 46.3 0.9 2.6 2 1 1 3 3 3 1 GAF domain PAS_4 PF08448.10 AAAP01003874.1_10 - 5.6e-11 42.7 0.0 3e-10 40.3 0.0 2.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003874.1_10 - 9.9e-09 35.2 0.0 4.2e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 AAAP01003874.1_10 - 2.5e-06 28.2 1.0 0.00014 22.5 0.2 3.7 3 1 0 3 3 3 1 GAF domain PAS_8 PF13188.7 AAAP01003874.1_10 - 0.00032 20.7 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AAAP01003874.1_10 - 0.0009 19.5 0.0 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain Phasin_2 PF09361.10 AAAP01003874.1_11 - 0.038 14.2 0.3 0.048 13.9 0.3 1.1 1 0 0 1 1 1 0 Phasin protein PNMA PF14893.6 AAAP01003874.1_11 - 0.041 13.3 0.4 0.048 13.1 0.4 1.0 1 0 0 1 1 1 0 PNMA STAS_2 PF13466.6 AAAP01003874.1_12 - 1e-09 38.6 0.0 1.5e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003874.1_12 - 5.8e-08 32.4 0.0 6.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 STAS domain SpoIIE PF07228.12 AAAP01003874.1_13 - 3.1e-50 170.8 0.1 5.5e-50 170.0 0.1 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 AAAP01003874.1_13 - 1.7e-19 70.0 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HAMP PF00672.25 AAAP01003874.1_13 - 4.4e-08 33.4 1.8 0.00014 22.2 0.1 3.0 2 0 0 2 2 2 2 HAMP domain dCache_3 PF14827.6 AAAP01003874.1_13 - 5.3e-06 26.3 0.3 5.3e-06 26.3 0.3 2.6 2 1 0 2 2 2 1 Double sensory domain of two-component sensor kinase FUSC PF04632.12 AAAP01003874.1_13 - 0.035 12.7 7.9 0.072 11.6 7.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PAS_4 PF08448.10 AAAP01003874.1_13 - 0.066 13.5 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 PAS fold Formyl_trans_N PF00551.19 AAAP01003874.1_14 - 6e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase LysM PF01476.20 AAAP01003874.1_14 - 0.036 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 LysM domain ABC_sub_bind PF04392.12 AAAP01003874.1_15 - 3.7e-27 95.3 0.1 4.8e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_6 PF13458.6 AAAP01003874.1_15 - 0.00026 20.8 0.5 0.0006 19.6 0.4 1.5 1 1 0 1 1 1 1 Periplasmic binding protein Rhomboid_N PF12122.8 AAAP01003874.1_15 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease MFS_1 PF07690.16 AAAP01003874.1_16 - 4.9e-34 117.8 70.8 4.2e-29 101.6 37.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01003874.1_16 - 1.1e-06 27.8 14.8 1.1e-06 27.8 14.8 3.7 2 2 0 2 2 2 1 Sugar (and other) transporter sCache_3_2 PF17203.4 AAAP01003874.1_16 - 8.1e-05 22.8 0.1 0.00023 21.3 0.1 1.7 1 1 0 1 1 1 1 Single cache domain 3 HAMP PF00672.25 AAAP01003874.1_16 - 0.00025 21.4 0.0 0.00062 20.1 0.0 1.7 1 0 0 1 1 1 1 HAMP domain MFS_1_like PF12832.7 AAAP01003874.1_16 - 0.00034 19.6 2.8 0.00034 19.6 2.8 2.5 2 1 0 3 3 3 1 MFS_1 like family LacY_symp PF01306.19 AAAP01003874.1_16 - 0.0018 17.1 3.9 0.0018 17.1 3.9 3.0 3 0 0 3 3 3 1 LacY proton/sugar symporter BT1 PF03092.16 AAAP01003874.1_16 - 0.0031 15.8 4.2 0.0031 15.8 4.2 2.0 2 0 0 2 2 2 1 BT1 family TetR_C_25 PF17933.1 AAAP01003874.1_16 - 0.073 13.4 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain sCache_3_2 PF17203.4 AAAP01003874.1_17 - 0.009 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Single cache domain 3 DUF2275 PF10039.9 AAAP01003874.1_17 - 0.24 11.5 2.1 14 5.7 0.3 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) Vma12 PF11712.8 AAAP01003874.1_17 - 7.9 6.5 7.5 25 4.9 0.3 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Asp_Glu_race PF01177.22 AAAP01003874.1_18 - 1.1e-28 100.7 0.0 1.3e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Glyco_transf_4 PF13439.6 AAAP01003874.1_19 - 4.2e-17 62.7 4.7 3.4e-16 59.7 4.5 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AAAP01003874.1_19 - 6.6e-14 52.5 0.2 1.2e-13 51.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003874.1_19 - 3e-13 49.7 0.0 1.5e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003874.1_19 - 1.3e-07 32.2 9.8 1.3e-07 32.2 9.8 2.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AAAP01003874.1_19 - 0.039 14.3 0.0 0.092 13.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 SNase PF00565.17 AAAP01003874.1_21 - 0.0029 18.0 0.0 0.0042 17.5 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue tRNA-synt_2c PF01411.19 AAAP01003874.1_22 - 1e-215 717.4 0.0 1.3e-215 717.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AAAP01003874.1_22 - 1.2e-21 77.6 2.9 3.3e-21 76.2 2.9 1.8 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 AAAP01003874.1_22 - 2.6e-18 65.9 0.3 6.4e-18 64.6 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Sulfate_transp PF00916.20 AAAP01003874.1_24 - 1.5e-33 116.1 24.5 2.1e-33 115.6 24.5 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 AAAP01003874.1_24 - 3.7e-15 55.8 0.0 1e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 AAAP01003874.1_24 - 4.1e-12 45.8 0.0 7.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAAP01003874.1_24 - 0.019 15.3 0.3 0.078 13.3 0.3 2.1 1 0 0 1 1 1 0 STAS domain PAS_9 PF13426.7 AAAP01003874.1_25 - 7.4e-28 96.9 0.0 4.2e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.26 AAAP01003874.1_25 - 8.9e-24 84.2 0.0 2.1e-23 83.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01003874.1_25 - 2.3e-19 69.5 0.0 8.8e-11 41.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AAAP01003874.1_25 - 2.4e-19 69.6 0.0 3.8e-08 33.6 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AAAP01003874.1_25 - 1.4e-14 54.2 0.2 3.1e-08 33.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 AAAP01003874.1_25 - 6.7e-12 45.3 3.4 3e-11 43.2 0.0 3.1 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003874.1_25 - 5.2e-10 39.1 0.1 3.7e-07 30.0 0.0 3.4 3 0 0 3 3 3 1 PAS domain HATPase_c_5 PF14501.6 AAAP01003874.1_25 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 GHKL domain DUF2353 PF09789.9 AAAP01003874.1_25 - 0.064 12.6 0.2 0.76 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) CMV_1a PF12467.8 AAAP01003874.1_26 - 0.16 12.3 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family SpoIIE PF07228.12 AAAP01003874.1_27 - 1.1e-30 107.0 0.0 1.8e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AAAP01003874.1_27 - 8.6e-18 64.5 0.0 1.5e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AAAP01003874.1_28 - 4.4e-16 59.0 0.1 7.1e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AAAP01003874.1_28 - 0.1 13.1 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2863 PF11062.8 AAAP01003874.1_28 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) STAS PF01740.21 AAAP01003874.1_29 - 8.9e-12 44.7 0.0 9.9e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAAP01003874.1_29 - 1.8e-09 37.8 0.1 2.3e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 STAS domain MCPsignal PF00015.21 AAAP01003874.1_30 - 3.1e-35 121.5 28.0 3.1e-35 121.5 28.0 2.6 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003874.1_30 - 2.8e-10 40.4 0.3 2.8e-10 40.4 0.3 4.2 5 1 0 5 5 5 1 HAMP domain DUF1664 PF07889.12 AAAP01003874.1_30 - 0.00014 21.8 16.9 0.0029 17.6 2.2 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003874.1_30 - 0.031 14.5 25.4 0.029 14.6 3.5 5.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) LapA_dom PF06305.11 AAAP01003874.1_30 - 0.82 9.5 4.1 7.2 6.5 0.3 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Baculo_F PF12259.8 AAAP01003874.1_30 - 1.2 7.5 4.4 1.9 6.9 4.4 1.3 1 0 0 1 1 1 0 Baculovirus F protein DUF3450 PF11932.8 AAAP01003874.1_30 - 1.2 8.3 22.4 0.042 13.2 2.5 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 AAAP01003874.1_30 - 2.2 8.8 12.3 5.1 7.6 3.4 3.5 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 AAAP01003874.1_30 - 3.2 8.2 8.0 11 6.4 0.7 3.1 2 2 0 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.9 AAAP01003874.1_30 - 3.7 7.9 12.3 6.9 7.0 1.8 4.0 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 AAAP01003874.1_30 - 5.3 7.1 16.6 3 7.9 8.1 2.8 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 AAAP01003874.1_30 - 6.9 6.7 23.2 5.2 7.1 5.5 3.2 2 1 2 4 4 4 0 Laminin Domain II SKA1 PF07160.12 AAAP01003874.1_30 - 7.1 6.4 15.1 14 5.4 0.3 3.3 1 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Molybdopterin PF00384.22 AAAP01003874.1_32 - 1.4e-33 116.6 0.0 1.7e-21 76.7 0.0 2.8 2 2 0 2 2 2 2 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 AAAP01003874.1_32 - 3.4e-16 59.0 2.6 5.9e-16 58.2 2.6 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Molydop_binding PF01568.21 AAAP01003874.1_32 - 8.8e-11 41.8 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer4_11 PF13247.6 AAAP01003874.1_33 - 1.8e-23 82.5 8.7 1.8e-23 82.5 8.7 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003874.1_33 - 2.6e-14 53.5 23.3 9.4e-07 29.3 5.7 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003874.1_33 - 2e-11 43.8 25.0 1.1e-05 25.4 12.4 3.8 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AAAP01003874.1_33 - 9.6e-11 41.3 32.9 6.4e-06 26.0 1.2 5.0 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003874.1_33 - 1.1e-10 40.9 38.2 6.8e-08 32.0 1.7 5.5 6 0 0 6 6 6 3 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003874.1_33 - 1.3e-10 41.2 21.9 4.1e-05 23.7 6.8 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003874.1_33 - 4.3e-10 39.1 34.7 2.6e-05 24.0 1.2 4.8 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003874.1_33 - 7.8e-09 35.9 32.9 0.032 15.2 6.6 4.7 4 1 0 4 4 4 4 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003874.1_33 - 5.4e-06 26.5 34.2 0.029 14.9 0.8 4.8 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003874.1_33 - 7.6e-05 22.8 24.9 0.0024 18.0 8.9 3.8 4 1 0 4 4 4 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003874.1_33 - 0.00047 20.6 22.9 0.46 11.1 9.7 4.1 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003874.1_33 - 0.0039 17.6 25.3 0.27 11.7 8.9 3.9 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003874.1_33 - 0.038 14.5 1.4 0.038 14.5 1.4 3.8 5 0 0 5 5 4 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_16 PF13484.6 AAAP01003874.1_33 - 0.19 12.7 28.0 5.6 8.0 1.4 4.6 3 1 1 4 4 4 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AAAP01003874.1_33 - 0.54 10.5 21.1 0.36 11.0 1.6 4.0 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 AAAP01003874.1_33 - 1.8 8.4 18.8 0.12 12.1 2.4 3.8 3 1 1 4 4 4 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DmsC PF04976.12 AAAP01003874.1_34 - 2.7e-29 102.5 19.6 4.1e-29 101.9 19.6 1.2 1 0 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) DUF2946 PF11162.8 AAAP01003874.1_36 - 0.75 10.5 15.8 1.1 9.9 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TonB_dep_Rec PF00593.24 AAAP01003874.1_37 - 6.8e-52 177.9 27.5 6.8e-52 177.9 27.5 1.5 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AAAP01003874.1_37 - 6.2e-12 46.0 0.9 1.9e-09 38.0 0.0 3.1 2 0 0 2 2 2 2 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAAP01003874.1_37 - 2e-09 37.0 5.6 2e-09 37.0 5.6 1.9 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family BNR_2 PF13088.6 AAAP01003874.1_38 - 4.3e-08 32.8 0.0 0.0025 17.2 0.0 2.7 3 1 0 3 3 3 2 BNR repeat-like domain BNR_4 PF15892.5 AAAP01003874.1_38 - 0.00069 19.1 0.0 0.033 13.5 0.0 2.8 2 2 2 4 4 4 1 BNR repeat-containing family member BNR PF02012.20 AAAP01003874.1_38 - 0.0017 18.1 4.9 5.6 7.4 0.9 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat DUF4224 PF13986.6 AAAP01003874.1_38 - 0.022 14.6 0.0 0.73 9.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) TonB_C PF03544.14 AAAP01003874.1_39 - 3.7e-18 65.7 0.0 9.2e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AAAP01003874.1_39 - 0.029 14.6 0.0 0.029 14.6 0.0 2.1 2 0 0 2 2 2 0 TonB C terminal MotA_ExbB PF01618.16 AAAP01003874.1_40 - 3e-31 107.8 0.3 4.3e-31 107.3 0.3 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AAAP01003874.1_41 - 2.5e-29 102.1 0.0 2.7e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 AAAP01003874.1_41 - 0.035 14.3 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) PsbH PF00737.20 AAAP01003874.1_41 - 0.98 9.2 4.4 1.7 8.5 4.4 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein ExbD PF02472.16 AAAP01003874.1_42 - 2.9e-22 79.2 0.0 3.8e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TauE PF01925.19 AAAP01003874.1_43 - 1.6e-45 155.6 45.4 1.9e-45 155.3 45.4 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Ribosomal_S9 PF00380.19 AAAP01003874.1_45 - 1.9e-46 157.5 0.1 2.3e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 AAAP01003874.1_46 - 3e-50 169.7 0.0 3.7e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HATPase_c PF02518.26 AAAP01003874.1_47 - 4.2e-16 59.4 0.0 6.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003874.1_47 - 6.6e-11 42.1 0.1 2.3e-10 40.4 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 AAAP01003874.1_47 - 2.4e-10 40.6 0.0 3.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Cache domain Oberon_cc PF16312.5 AAAP01003874.1_47 - 0.0081 16.1 2.3 0.013 15.4 2.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of Oberon HATPase_c_2 PF13581.6 AAAP01003874.1_47 - 0.19 11.7 0.6 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 AAAP01003874.1_48 - 3.2e-46 157.3 0.1 7.6e-25 88.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 AAAP01003874.1_48 - 1e-27 95.9 1.6 1e-27 95.9 1.6 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AAAP01003874.1_48 - 8e-19 68.6 9.4 1.1e-06 28.7 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003874.1_48 - 4.2e-09 36.2 2.9 0.00021 20.8 0.0 4.2 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003874.1_48 - 9.8e-06 25.2 0.1 0.08 12.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_CTD PF16326.5 AAAP01003874.1_48 - 0.0001 22.4 7.6 0.00022 21.4 4.5 2.7 2 0 0 2 2 2 1 ABC transporter C-terminal domain RsgA_GTPase PF03193.16 AAAP01003874.1_48 - 0.00011 22.2 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003874.1_48 - 0.00021 21.4 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 AAAP01003874.1_48 - 0.00062 20.3 0.1 0.28 11.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 AAAP01003874.1_48 - 0.001 19.5 3.6 0.12 12.8 0.0 3.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 AAAP01003874.1_48 - 0.0016 18.6 2.7 1.1 9.3 0.0 3.1 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_30 PF13604.6 AAAP01003874.1_48 - 0.0018 18.0 0.4 0.13 12.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AAAP01003874.1_48 - 0.0027 17.4 0.3 3.4 7.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 AAAP01003874.1_48 - 0.003 17.3 0.5 0.83 9.4 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 AAAP01003874.1_48 - 0.0034 17.3 0.4 3.5 7.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.6 AAAP01003874.1_48 - 0.0035 17.5 1.1 0.61 10.4 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 AAAP01003874.1_48 - 0.0056 16.7 0.6 1.5 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AAAP01003874.1_48 - 0.0071 15.6 0.9 0.61 9.2 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.6 AAAP01003874.1_48 - 0.0095 15.7 4.1 5 6.7 0.0 3.5 4 0 0 4 4 3 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01003874.1_48 - 0.011 16.0 0.7 1.5 9.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 AAAP01003874.1_48 - 0.012 15.5 0.4 0.073 13.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 AAAP01003874.1_48 - 0.017 15.5 0.3 4.9 7.6 0.1 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 AAAP01003874.1_48 - 0.024 14.2 0.2 0.58 9.7 0.0 2.4 3 0 0 3 3 2 0 P-loop containing dynein motor region TsaE PF02367.17 AAAP01003874.1_48 - 0.025 14.6 0.8 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 AAAP01003874.1_48 - 0.026 14.3 0.6 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 AAAP01003874.1_48 - 0.029 14.6 4.4 0.47 10.7 0.0 3.4 3 1 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 AAAP01003874.1_48 - 0.049 13.5 1.5 0.54 10.2 0.1 2.8 3 0 0 3 3 2 0 NTPase AAA_25 PF13481.6 AAAP01003874.1_48 - 0.052 13.1 3.6 2.2 7.8 0.1 3.6 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 AAAP01003874.1_48 - 0.061 12.3 1.6 1.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 AAAP01003874.1_48 - 0.077 12.4 0.2 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AAAP01003874.1_48 - 0.1 12.7 4.0 7.2 6.8 0.2 3.8 3 2 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 AAAP01003874.1_48 - 0.11 12.2 0.2 16 5.2 0.0 3.4 3 1 1 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.6 AAAP01003874.1_48 - 0.15 12.6 10.3 0.66 10.4 0.1 3.8 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 AAAP01003874.1_48 - 0.68 10.3 9.7 0.57 10.5 0.0 3.5 3 1 0 3 3 2 0 AAA ATPase domain cobW PF02492.19 AAAP01003874.1_48 - 0.82 9.2 2.2 25 4.4 0.2 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DivIC PF04977.15 AAAP01003874.1_48 - 1.1 9.0 9.9 0.74 9.6 2.6 2.9 3 0 0 3 3 2 0 Septum formation initiator AAA_13 PF13166.6 AAAP01003874.1_48 - 4.3 5.8 11.5 2.7 6.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain NDK PF00334.19 AAAP01003874.1_49 - 3.5e-53 179.2 0.1 3.9e-53 179.1 0.1 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HTH_3 PF01381.22 AAAP01003874.1_50 - 4.4e-13 49.1 0.1 2.7e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AAAP01003874.1_50 - 2.1e-10 40.8 0.8 2.1e-10 40.8 0.8 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 AAAP01003874.1_50 - 3.5e-08 33.3 0.1 5.7e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4228 PF14009.6 AAAP01003874.1_50 - 0.0089 16.4 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) Pou PF00157.17 AAAP01003874.1_50 - 0.047 13.7 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain YdaS_antitoxin PF15943.5 AAAP01003874.1_50 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT IF2_N PF04760.15 AAAP01003874.1_50 - 0.17 11.7 0.0 5.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_26 PF13443.6 AAAP01003874.1_50 - 0.19 12.2 0.0 0.47 10.9 0.0 1.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain GGDEF PF00990.21 AAAP01003874.1_51 - 1.4e-45 154.9 0.0 3e-45 153.8 0.0 1.6 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AAAP01003874.1_51 - 2.4e-13 50.5 0.0 3.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Cache domain Pkr1 PF08636.10 AAAP01003874.1_51 - 0.12 12.5 0.2 0.33 11.1 0.2 1.6 1 0 0 1 1 1 0 ER protein Pkr1 HATPase_c PF02518.26 AAAP01003874.1_52 - 1.1e-25 90.3 0.0 2.2e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAAP01003874.1_52 - 1.3e-15 57.9 0.0 7.6e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Cache domain PAS_4 PF08448.10 AAAP01003874.1_52 - 7.2e-14 52.0 1.1 7.2e-14 52.0 1.1 2.7 2 1 1 3 3 3 1 PAS fold HisKA PF00512.25 AAAP01003874.1_52 - 8.7e-12 44.9 0.7 3.6e-11 42.9 0.2 2.3 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AAAP01003874.1_52 - 2.6e-09 37.1 0.2 5.3e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AAAP01003874.1_52 - 2.9e-09 37.1 0.1 8e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01003874.1_52 - 8.8e-08 32.3 0.0 1.9e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AAAP01003874.1_52 - 0.00022 21.2 0.1 0.00069 19.6 0.1 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AAAP01003874.1_52 - 0.0035 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AAAP01003874.1_52 - 0.031 14.1 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003874.1_52 - 0.049 13.6 0.2 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF4570 PF15134.6 AAAP01003874.1_52 - 0.16 12.0 0.3 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) BPD_transp_1 PF00528.22 AAAP01003874.1_53 - 7.2e-11 42.2 9.6 7.2e-11 42.2 9.6 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 AAAP01003874.1_53 - 0.0026 17.7 0.3 0.035 14.1 0.0 2.9 2 0 0 2 2 2 1 Small integral membrane protein (DUF2273) BPD_transp_1 PF00528.22 AAAP01003874.1_54 - 3.9e-25 88.7 10.6 3.9e-25 88.7 10.6 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_11 PF13531.6 AAAP01003874.1_55 - 1.6e-41 142.5 1.6 2.1e-41 142.2 1.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01003874.1_55 - 6.5e-12 46.0 6.5 8.6e-12 45.6 6.5 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AAAP01003874.1_55 - 3.3e-09 36.5 0.1 1.1e-08 34.8 0.1 1.8 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAAP01003874.1_55 - 1.5e-05 24.9 0.2 2e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AAAP01003874.1_55 - 0.00039 19.6 0.0 0.00075 18.7 0.0 1.5 1 0 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 AAAP01003874.1_55 - 0.00047 19.9 0.6 0.00083 19.1 0.6 1.5 1 1 0 1 1 1 1 PBP superfamily domain GGDEF PF00990.21 AAAP01003874.1_56 - 1.7e-30 105.9 0.0 1.6e-29 102.7 0.0 2.1 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Ribosomal_L33 PF00471.20 AAAP01003874.1_57 - 3.1e-15 56.3 0.2 3.5e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Response_reg PF00072.24 AAAP01003874.1_58 - 5.7e-27 94.1 0.3 6.4e-27 93.9 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF423 PF04241.15 AAAP01003874.1_59 - 2.7e-20 72.3 0.9 4.7e-20 71.6 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) FecR PF04773.13 AAAP01003874.1_60 - 1.9e-12 47.6 0.0 4.6e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 FecR protein Formyl_trans_N PF00551.19 AAAP01003874.1_61 - 9.8e-36 123.2 0.2 1.2e-35 122.9 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AAAP01003874.1_61 - 0.00014 21.5 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 AAAP01003874.1_61 - 0.019 14.9 0.1 0.059 13.4 0.0 1.7 2 0 0 2 2 2 0 ACT domain DUF3006 PF11213.8 AAAP01003874.1_62 - 0.07 13.4 0.2 0.07 13.4 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) Hemerythrin PF01814.23 AAAP01003874.1_63 - 9.2e-12 45.7 5.1 1.3e-11 45.2 4.7 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1708 PF08101.11 AAAP01003874.1_63 - 0.029 13.5 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF2249 PF10006.9 AAAP01003874.1_65 - 2.3e-27 94.6 1.3 1.9e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2249) TusA PF01206.17 AAAP01003874.1_65 - 0.024 14.4 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Sulfurtransferase TusA HTH_Crp_2 PF13545.6 AAAP01003874.1_66 - 2.4e-18 65.9 0.5 4.7e-18 64.9 0.5 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003874.1_66 - 2.6e-12 46.6 0.0 4.4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MarR_2 PF12802.7 AAAP01003874.1_66 - 0.0021 17.9 0.5 0.012 15.4 0.5 2.2 1 1 0 1 1 1 1 MarR family Crp PF00325.20 AAAP01003874.1_66 - 0.019 14.6 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_24 PF13412.6 AAAP01003874.1_66 - 0.04 13.5 0.2 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AAAP01003874.1_66 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain cNMP_binding PF00027.29 AAAP01003874.1_67 - 7.4e-15 54.8 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AAAP01003874.1_67 - 5.2e-11 42.4 0.0 1.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Asp_Glu_race PF01177.22 AAAP01003874.1_68 - 5.1e-25 88.6 0.0 6.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FIST PF08495.10 AAAP01003874.1_68 - 0.0018 18.3 0.1 0.0043 17.1 0.1 1.6 1 1 1 2 2 2 1 FIST N domain Rop-like PF05082.13 AAAP01003874.1_69 - 4.2e-29 100.2 2.0 4.9e-29 99.9 2.0 1.0 1 0 0 1 1 1 1 Rop-like Seryl_tRNA_N PF02403.22 AAAP01003874.1_69 - 0.037 14.3 0.5 0.057 13.7 0.4 1.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.13 AAAP01003874.1_69 - 0.059 13.8 2.5 0.082 13.3 1.3 1.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Cys_rich_KTR PF14205.6 AAAP01003874.1_70 - 0.012 15.4 3.2 0.015 15.0 3.2 1.3 1 0 0 1 1 1 0 Cysteine-rich KTR B12-binding PF02310.19 AAAP01003874.1_71 - 1.9e-20 73.1 0.1 2.9e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AAAP01003874.1_71 - 3.8e-13 49.7 0.2 8.5e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 B12 binding domain HATPase_c PF02518.26 AAAP01003874.1_72 - 7.3e-25 87.7 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003874.1_72 - 1.6e-13 50.5 0.0 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01003874.1_72 - 0.0031 17.3 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_4TM PF16926.5 AAAP01003874.1_72 - 0.029 14.0 0.2 0.16 11.5 0.0 2.1 2 1 0 2 2 2 0 Archaeal 4TM region of histidine kinase DUF1192 PF06698.11 AAAP01003874.1_72 - 0.099 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) adh_short PF00106.25 AAAP01003874.1_73 - 1.9e-43 148.2 3.7 2.4e-43 147.9 3.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003874.1_73 - 9.1e-42 143.2 4.4 1.1e-41 142.9 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003874.1_73 - 8.1e-07 29.1 2.5 2.9e-06 27.3 2.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003874.1_73 - 0.0021 17.6 0.6 0.0056 16.2 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 AAAP01003874.1_73 - 0.0048 17.1 0.8 0.012 15.8 0.8 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 AAAP01003874.1_73 - 0.024 14.8 0.2 0.04 14.1 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AAAP01003874.1_73 - 0.03 14.2 1.8 0.042 13.7 1.8 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAAP01003874.1_73 - 0.042 14.1 0.2 0.09 13.0 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.26 AAAP01003874.1_73 - 0.096 12.7 3.7 0.18 11.8 3.7 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 AAAP01003874.1_73 - 0.16 12.1 0.5 0.24 11.4 0.5 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 AAAP01003874.1_73 - 0.16 12.0 1.0 0.27 11.3 1.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ECH_2 PF16113.5 AAAP01003874.1_74 - 6.6e-125 417.0 0.0 7.9e-125 416.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 AAAP01003874.1_74 - 6.2e-31 107.6 0.0 8.3e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 2_5_RNA_ligase2 PF13563.6 AAAP01003874.1_74 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily AMP-binding PF00501.28 AAAP01003874.1_75 - 6.5e-102 341.3 0.0 8.2e-102 340.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003874.1_75 - 5e-14 53.0 0.6 1.1e-13 51.9 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTS-HPr PF00381.19 AAAP01003874.1_75 - 0.18 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 PTS HPr component phosphorylation site FCD PF07729.12 AAAP01003874.1_76 - 1.1e-30 106.6 5.6 1.1e-30 106.6 5.6 1.9 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 AAAP01003874.1_76 - 1.7e-16 59.6 0.5 3e-16 58.8 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Acyl-CoA_dh_1 PF00441.24 AAAP01003874.1_77 - 2.7e-50 170.5 1.0 3.9e-50 169.9 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAAP01003874.1_77 - 3.1e-33 114.8 0.1 5.8e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003874.1_77 - 3.6e-27 94.4 0.0 8.3e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAAP01003874.1_77 - 1.8e-25 89.7 0.5 3.2e-25 89.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AAAP01003874.1_78 - 1.4e-49 168.3 5.3 2.4e-49 167.5 5.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AAAP01003874.1_78 - 1.6e-41 141.4 0.1 1.6e-41 141.4 0.1 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AAAP01003874.1_78 - 1.5e-08 35.1 0.5 4.1e-08 33.7 0.3 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AAAP01003874.1_78 - 0.0016 18.4 0.7 0.0028 17.6 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AAAP01003874.1_78 - 0.012 14.9 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC_tran PF00005.27 AAAP01003874.1_79 - 1.6e-27 96.7 0.0 2.1e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AAAP01003874.1_79 - 3.9e-10 39.4 0.0 7.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AAAP01003874.1_79 - 5.5e-05 23.8 0.1 9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AAAP01003874.1_79 - 0.007 16.2 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003874.1_79 - 0.0089 15.5 0.7 0.096 12.1 0.2 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AAAP01003874.1_79 - 0.012 15.4 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003874.1_79 - 0.013 15.9 0.1 0.58 10.6 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 AAAP01003874.1_79 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AAAP01003874.1_79 - 0.048 14.0 0.1 0.058 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003874.1_79 - 0.062 13.2 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 AAAP01003874.1_79 - 0.073 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 AAAP01003874.1_79 - 0.34 10.6 0.2 0.59 9.8 0.1 1.4 2 0 0 2 2 2 0 AAA ATPase domain AMP-binding PF00501.28 AAAP01003874.1_80 - 3.2e-73 246.8 0.0 3.8e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SH3_2 PF07653.17 AAAP01003874.1_80 - 0.062 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain BPD_transp_2 PF02653.16 AAAP01003874.1_81 - 1.7e-08 33.9 4.3 2e-08 33.7 4.3 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component OST3_OST6 PF04756.13 AAAP01003874.1_81 - 0.03 13.7 1.5 0.03 13.7 1.5 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF4579 PF15158.6 AAAP01003874.1_81 - 0.036 13.8 2.9 0.041 13.7 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) DUF3789 PF12664.7 AAAP01003874.1_81 - 0.12 12.1 2.0 0.23 11.2 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF2407_C PF13373.6 AAAP01003874.1_81 - 0.31 11.2 1.5 0.38 10.9 1.5 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Peptidase_M23 PF01551.22 AAAP01003875.1_1 - 5e-33 113.2 2.9 5e-33 113.2 2.9 2.2 3 0 0 3 3 3 1 Peptidase family M23 Proteasome PF00227.26 AAAP01003875.1_2 - 1.4e-06 28.0 0.1 3.6e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit DUF192 PF02643.15 AAAP01003875.1_3 - 4.3e-30 103.7 0.0 5.4e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 TOBE_3 PF12857.7 AAAP01003875.1_3 - 0.096 12.6 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 TOBE-like domain Response_reg PF00072.24 AAAP01003875.1_4 - 1.1e-25 90.0 0.1 1.8e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003875.1_4 - 3.9e-19 68.0 0.5 6e-19 67.4 0.5 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003875.1_4 - 7.5e-09 35.1 1.0 3.4e-08 33.0 0.3 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01003875.1_4 - 5.1e-06 26.1 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain GFO_IDH_MocA PF01408.22 AAAP01003875.1_4 - 0.001 19.9 0.1 0.0051 17.6 0.0 2.1 2 1 1 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold Sigma70_ECF PF07638.11 AAAP01003875.1_4 - 0.0022 17.9 0.2 0.004 17.1 0.2 1.4 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AAAP01003875.1_4 - 0.0049 16.4 0.1 0.015 14.8 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 AAAP01003875.1_4 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AAAP01003875.1_4 - 0.014 14.8 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AAAP01003875.1_4 - 0.024 14.7 0.6 0.077 13.0 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix FleQ PF06490.11 AAAP01003875.1_4 - 0.033 14.6 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HTH_3 PF01381.22 AAAP01003875.1_4 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix Response_reg PF00072.24 AAAP01003875.1_5 - 1.4e-26 92.9 0.0 2.3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AAAP01003875.1_5 - 3.4e-18 64.9 0.3 5.5e-18 64.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AAAP01003875.1_5 - 0.011 15.4 0.2 0.023 14.4 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 AAAP01003875.1_5 - 0.015 15.1 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain ABC1 PF03109.16 AAAP01003875.1_5 - 0.028 14.6 0.3 0.049 13.8 0.3 1.5 1 1 0 1 1 1 0 ABC1 family HATPase_c PF02518.26 AAAP01003875.1_6 - 5.6e-19 68.7 0.0 9.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AAAP01003875.1_6 - 4.4e-17 62.1 0.0 9.7e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003875.1_6 - 1.9e-11 44.1 0.0 3.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003875.1_6 - 2.6e-11 43.7 0.1 8.2e-11 42.1 0.1 1.9 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003875.1_6 - 5e-08 32.9 0.9 1.2e-07 31.6 0.0 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01003875.1_6 - 1.3e-06 28.6 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AAAP01003875.1_6 - 2.1e-06 27.6 0.0 4.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 AAAP01003875.1_6 - 4.4e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AAAP01003875.1_6 - 0.0032 17.3 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003875.1_6 - 0.011 15.7 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF3188 PF11384.8 AAAP01003875.1_6 - 0.017 14.9 0.2 0.066 12.9 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Tricorn_PDZ PF14685.6 AAAP01003875.1_6 - 0.066 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain DctP PF03480.13 AAAP01003875.1_7 - 7.4e-105 350.4 0.0 9e-105 350.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 DUF1850 PF08905.11 AAAP01003875.1_8 - 4.1e-25 87.9 0.0 4.9e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1850) DctM PF06808.12 AAAP01003875.1_9 - 7.1e-83 278.7 59.5 1.1e-57 195.8 23.2 2.3 1 1 1 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component NMT1_3 PF16868.5 AAAP01003875.1_10 - 1.5e-88 297.0 0.3 1.7e-88 296.8 0.3 1.0 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 AAAP01003875.1_10 - 1.5e-08 34.5 0.6 2.7e-08 33.7 0.5 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAAP01003875.1_10 - 4.2e-08 33.4 0.1 6.3e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AAAP01003875.1_10 - 0.00014 21.3 0.2 0.0005 19.6 0.1 1.8 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Cofac_haem_bdg PF04187.13 AAAP01003875.1_11 - 5.4e-52 176.9 0.9 7.8e-52 176.4 0.9 1.2 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN TraB PF01963.17 AAAP01003875.1_11 - 0.0044 17.0 0.5 0.016 15.1 0.1 1.9 1 1 1 2 2 2 1 TraB family Erythro_esteras PF05139.14 AAAP01003875.1_11 - 0.034 14.0 0.2 0.044 13.6 0.2 1.2 1 0 0 1 1 1 0 Erythromycin esterase DnaJ_C PF01556.18 AAAP01003875.1_12 - 1.8e-34 118.9 0.0 2.7e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AAAP01003875.1_12 - 2.5e-23 82.0 0.2 4.9e-23 81.0 0.1 1.6 2 0 0 2 2 2 1 DnaJ domain 17kDa_Anti_2 PF16998.5 AAAP01003875.1_13 - 2.4e-13 50.0 0.3 3e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 17 kDa outer membrane surface antigen Rick_17kDa_Anti PF05433.15 AAAP01003875.1_13 - 1.1e-05 25.1 19.5 2.6e-05 24.0 19.5 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF5061 PF16587.5 AAAP01003875.1_13 - 0.00035 20.6 0.3 0.00035 20.6 0.3 2.3 2 1 1 3 3 3 1 17 kDa common-antigen outer membrane protein DUF456 PF04306.13 AAAP01003875.1_13 - 0.0078 16.5 1.7 0.01 16.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 AAAP01003875.1_13 - 0.11 12.6 17.7 0.84 9.7 17.7 2.2 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 AAAP01003875.1_13 - 0.44 10.3 17.8 0.9 9.3 17.8 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Putative_PNPOx PF01243.20 AAAP01003875.1_14 - 7.9e-25 86.9 0.0 1.1e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 AAAP01003875.1_14 - 1.9e-15 56.7 6.8 3.4e-15 55.8 6.8 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 AAAP01003875.1_14 - 1.2e-05 25.8 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AAAP01003875.1_14 - 0.0041 16.7 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Cation_efflux PF01545.21 AAAP01003875.1_15 - 4.5e-37 127.7 10.9 5.3e-37 127.5 10.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003875.1_15 - 1.5e-24 85.9 0.4 4.2e-24 84.5 0.3 1.8 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter PhoR PF11808.8 AAAP01003875.1_15 - 1.1 9.7 5.9 3.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR DUF179 PF02622.15 AAAP01003875.1_16 - 9.4e-47 158.9 0.0 1.1e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 FAD_binding_6 PF00970.24 AAAP01003875.1_16 - 0.031 14.6 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Cytochrom_C PF00034.21 AAAP01003875.1_18 - 1.3e-10 42.2 1.2 0.00021 22.4 0.0 2.7 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AAAP01003875.1_18 - 2.7e-10 40.4 0.9 0.00094 19.5 0.8 2.4 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Lon_2 PF13337.6 AAAP01003875.1_18 - 0.0056 15.3 0.0 0.0076 14.8 0.0 1.1 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease Cytochrome_C7 PF14522.6 AAAP01003875.1_18 - 0.034 14.2 0.0 8.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AAAP01003875.1_18 - 0.065 13.0 1.3 9.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) EB_dh PF09459.10 AAAP01003875.1_19 - 8.5e-44 150.4 0.1 8.3e-42 143.9 0.1 2.0 1 1 0 1 1 1 1 Ethylbenzene dehydrogenase CBS PF00571.28 AAAP01003875.1_20 - 1e-26 93.1 1.0 1.2e-15 57.7 0.3 2.1 2 0 0 2 2 2 2 CBS domain adh_short_C2 PF13561.6 AAAP01003875.1_21 - 1.4e-61 208.0 1.1 1.6e-61 207.8 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003875.1_21 - 4.9e-54 182.8 0.3 6.6e-54 182.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003875.1_21 - 1.5e-12 47.8 0.3 2.5e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003875.1_21 - 1.4e-06 28.3 2.2 2.1e-06 27.8 2.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 AAAP01003875.1_21 - 0.00032 20.0 0.3 0.0011 18.4 0.0 1.9 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 AAAP01003875.1_21 - 0.00074 19.1 0.4 0.0015 18.0 0.2 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AAAP01003875.1_21 - 0.0067 15.8 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.15 AAAP01003875.1_21 - 0.012 15.7 0.1 0.031 14.5 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 AAAP01003875.1_21 - 0.082 12.5 0.8 0.12 11.9 0.8 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 AAAP01003875.1_21 - 0.2 11.0 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_S41 PF03572.18 AAAP01003875.1_22 - 3.8e-42 143.7 0.0 5.8e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 AAAP01003875.1_22 - 5.9e-13 48.5 3.5 9.9e-13 47.7 1.1 2.7 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 AAAP01003875.1_22 - 9.3e-12 45.1 0.2 2.5e-11 43.7 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AAAP01003875.1_22 - 1.3e-06 28.7 0.2 2.8e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 AAAP01003875.1_22 - 0.0022 17.9 0.4 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain RNB PF00773.19 AAAP01003875.1_23 - 3.3e-93 312.6 0.0 4.2e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain S1 PF00575.23 AAAP01003875.1_23 - 7.6e-10 39.0 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain CSD2 PF17876.1 AAAP01003875.1_23 - 6.3e-08 32.7 0.0 3.7e-06 27.0 0.0 3.3 4 0 0 4 4 4 1 Cold shock domain HTH_12 PF08461.10 AAAP01003875.1_23 - 0.47 10.4 2.0 3.4 7.7 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain DctQ PF04290.12 AAAP01003875.1_25 - 3.2e-06 27.1 5.8 3.2e-06 27.1 5.8 1.7 1 1 1 2 2 2 2 Tripartite ATP-independent periplasmic transporters, DctQ component DctM PF06808.12 AAAP01003875.1_26 - 1.1e-45 156.3 48.5 1.5e-45 155.8 48.5 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component ABC_tran PF00005.27 AAAP01003875.1_27 - 1e-51 175.0 0.1 2.8e-24 86.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 AAAP01003875.1_27 - 3.4e-16 59.9 5.6 0.00013 21.9 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AAAP01003875.1_27 - 8.4e-15 54.6 3.4 1e-12 47.9 0.5 2.8 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 AAAP01003875.1_27 - 2.6e-09 36.9 1.2 0.31 10.4 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003875.1_27 - 1.9e-05 24.3 0.7 0.056 13.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AAAP01003875.1_27 - 2.2e-05 24.5 0.1 0.05 13.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 AAAP01003875.1_27 - 4.2e-05 23.9 1.4 0.082 13.2 0.2 3.5 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AAAP01003875.1_27 - 5.2e-05 23.8 0.3 5.2e-05 23.8 0.3 3.4 4 0 0 4 4 3 2 AAA domain NB-ARC PF00931.22 AAAP01003875.1_27 - 6.8e-05 22.2 0.0 0.032 13.4 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain AAA_18 PF13238.6 AAAP01003875.1_27 - 8.6e-05 23.1 0.1 0.35 11.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 AAAP01003875.1_27 - 0.00012 22.2 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_24 PF13479.6 AAAP01003875.1_27 - 0.00053 19.8 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.6 AAAP01003875.1_27 - 0.0017 17.1 3.3 0.19 10.4 0.0 3.5 2 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 AAAP01003875.1_27 - 0.0018 18.2 0.5 0.72 9.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 AAAP01003875.1_27 - 0.0019 18.4 1.6 3.8 7.8 0.0 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 AAAP01003875.1_27 - 0.0022 18.2 0.8 0.77 10.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain DLIC PF05783.11 AAAP01003875.1_27 - 0.0022 16.9 0.3 0.28 10.0 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 AAAP01003875.1_27 - 0.0059 16.8 0.9 1.1 9.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 AAAP01003875.1_27 - 0.0076 15.9 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AAAP01003875.1_27 - 0.012 16.0 6.9 0.5 10.7 0.1 3.6 2 2 1 3 3 3 0 AAA ATPase domain cobW PF02492.19 AAAP01003875.1_27 - 0.015 14.9 1.7 0.76 9.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 AAAP01003875.1_27 - 0.019 15.2 2.1 0.99 9.6 0.0 3.1 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 AAAP01003875.1_27 - 0.02 13.9 0.5 0.25 10.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 AAAP01003875.1_27 - 0.036 14.1 0.0 4.7 7.3 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA PF00004.29 AAAP01003875.1_27 - 0.038 14.4 0.8 1.1 9.6 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AAAP01003875.1_27 - 0.094 12.4 5.2 3.9 7.1 0.8 2.7 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 AAAP01003875.1_27 - 0.096 12.1 1.1 7.5 6.0 0.2 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 AAAP01003875.1_27 - 0.099 12.2 0.7 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.6 AAAP01003875.1_27 - 0.1 13.0 1.7 6 7.3 0.5 2.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AAAP01003875.1_27 - 0.13 12.1 2.8 7.1 6.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 AAAP01003875.1_27 - 0.14 11.8 1.2 15 5.1 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_15 PF13175.6 AAAP01003875.1_27 - 0.16 11.7 0.7 4.7 6.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 AAAP01003875.1_27 - 0.2 11.7 1.5 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 AAAP01003875.1_27 - 0.28 10.9 0.4 25 4.6 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 AAAP01003875.1_27 - 0.41 10.4 1.2 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ank_5 PF13857.6 AAAP01003875.1_28 - 6.1e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 AAAP01003875.1_28 - 0.0015 19.1 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AAAP01003875.1_28 - 0.012 16.1 0.0 0.77 10.5 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 AAAP01003875.1_28 - 0.014 15.8 0.1 5.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 AAAP01003875.1_28 - 0.054 14.1 0.0 0.22 12.1 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) CBS PF00571.28 AAAP01003875.1_29 - 4.2e-26 91.2 4.7 3.3e-14 53.0 1.6 2.1 2 0 0 2 2 2 2 CBS domain VAPB_antitox PF02697.14 AAAP01003875.1_29 - 0.13 13.0 0.1 2.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Putative antitoxin LMWPc PF01451.21 AAAP01003875.1_32 - 1.8e-40 138.6 0.0 2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SIR2 PF02146.17 AAAP01003875.1_33 - 8.9e-47 159.3 0.0 1.1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.20 AAAP01003875.1_33 - 0.002 18.2 0.1 0.0033 17.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Tmemb_55A PF09788.9 AAAP01003875.1_33 - 0.027 13.5 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Mu-like_Com PF10122.9 AAAP01003875.1_33 - 0.098 12.1 0.9 0.19 11.2 0.9 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com K_trans PF02705.16 AAAP01003875.1_34 - 2.8e-213 709.3 16.9 3.2e-213 709.1 16.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter K_trans PF02705.16 AAAP01003875.1_35 - 2e-211 703.2 14.9 2.4e-211 702.9 14.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter Pro_CA PF00484.19 AAAP01003875.1_36 - 4.5e-06 27.1 0.5 1.7e-05 25.1 0.5 1.8 1 1 0 1 1 1 1 Carbonic anhydrase TAT_signal PF10518.9 AAAP01003875.1_36 - 0.0063 16.3 0.6 0.0063 16.3 0.6 1.8 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Hemerythrin PF01814.23 AAAP01003875.1_38 - 3.7e-06 27.6 2.1 4.6e-06 27.3 2.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ABC_tran PF00005.27 AAAP01003875.1_39 - 2.8e-46 157.4 0.0 1.3e-21 77.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_CTD PF16326.5 AAAP01003875.1_39 - 1.3e-20 73.3 5.1 1.3e-20 73.3 5.1 1.7 2 0 0 2 2 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 AAAP01003875.1_39 - 1.4e-16 61.2 6.3 0.00039 20.3 0.1 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003875.1_39 - 5.3e-09 35.8 0.1 0.056 12.9 0.0 3.7 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003875.1_39 - 2.8e-08 33.4 0.2 0.0006 19.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003875.1_39 - 2.9e-08 34.3 3.3 0.00026 21.4 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 AAAP01003875.1_39 - 1.1e-06 28.6 0.2 0.0028 17.4 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003875.1_39 - 1.6e-06 28.1 0.1 0.039 13.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AAAP01003875.1_39 - 3.1e-06 27.3 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 AAAP01003875.1_39 - 3.5e-06 27.2 0.4 0.029 14.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 AAAP01003875.1_39 - 4.8e-06 26.3 3.5 0.001 18.7 0.1 3.5 4 1 0 4 4 2 1 AAA domain AAA_23 PF13476.6 AAAP01003875.1_39 - 6.7e-06 26.7 6.7 0.027 15.0 0.1 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 AAAP01003875.1_39 - 9.5e-06 25.6 0.2 0.09 12.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.12 AAAP01003875.1_39 - 1.3e-05 24.6 0.1 0.0088 15.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 AAAP01003875.1_39 - 2e-05 24.4 5.5 0.028 14.1 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 AAAP01003875.1_39 - 0.00016 22.0 4.0 0.3 11.4 1.1 3.6 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 AAAP01003875.1_39 - 0.00024 21.5 0.2 0.59 10.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AAAP01003875.1_39 - 0.00048 20.1 0.9 2 8.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AAAP01003875.1_39 - 0.00065 20.1 0.0 0.96 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 AAAP01003875.1_39 - 0.00067 19.4 0.1 0.45 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AAAP01003875.1_39 - 0.0007 20.1 0.1 2.1 8.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 AAAP01003875.1_39 - 0.0012 19.1 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 AAAP01003875.1_39 - 0.0012 18.8 0.4 0.23 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 AAAP01003875.1_39 - 0.0013 18.4 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 AAAP01003875.1_39 - 0.0022 17.6 0.7 0.68 9.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AAAP01003875.1_39 - 0.0039 16.2 1.4 0.15 11.0 0.2 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 AAAP01003875.1_39 - 0.0053 16.5 1.1 1.4 8.6 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 AAAP01003875.1_39 - 0.0068 16.3 0.3 1 9.3 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 AAAP01003875.1_39 - 0.012 15.3 1.2 2 8.1 0.1 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_13 PF13166.6 AAAP01003875.1_39 - 0.013 14.2 2.3 6 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 AAAP01003875.1_39 - 0.015 14.8 0.1 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 AAAP01003875.1_39 - 0.024 14.5 0.2 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 AAAP01003875.1_39 - 0.032 14.1 0.2 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 AAAP01003875.1_39 - 0.036 14.2 0.1 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 AAAP01003875.1_39 - 0.041 13.8 0.0 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain RuvB_N PF05496.12 AAAP01003875.1_39 - 0.045 13.5 0.1 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 AAAP01003875.1_39 - 0.064 13.5 8.2 0.53 10.5 0.0 3.7 4 1 1 5 5 2 0 AAA domain Dynamin_N PF00350.23 AAAP01003875.1_39 - 0.066 13.3 0.4 5 7.2 0.0 2.6 3 0 0 3 3 2 0 Dynamin family AAA_14 PF13173.6 AAAP01003875.1_39 - 0.097 12.7 0.0 8.2 6.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 AAAP01003875.1_39 - 0.1 12.2 0.6 11 5.6 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1192 PF06698.11 AAAP01003875.1_39 - 0.1 12.6 0.0 0.1 12.6 0.0 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF1192) CLP1_P PF16575.5 AAAP01003875.1_39 - 0.11 12.3 0.1 20 4.9 0.0 2.7 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 AAAP01003875.1_39 - 0.12 11.5 0.4 13 4.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 AAAP01003875.1_39 - 0.12 11.5 0.1 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 AAAP01003875.1_39 - 0.13 11.6 0.6 12 5.2 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 AAAP01003875.1_39 - 0.15 11.1 0.1 17 4.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Arf PF00025.21 AAAP01003875.1_39 - 0.23 10.9 0.3 6.6 6.2 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family dNK PF01712.19 AAAP01003875.1_39 - 0.34 10.8 0.4 23 4.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase HalX PF08663.10 AAAP01003875.1_39 - 0.35 11.2 4.5 1.5 9.2 4.5 2.1 1 0 0 1 1 1 0 HalX domain DUF1843 PF08898.10 AAAP01003875.1_39 - 0.41 11.2 0.1 0.41 11.2 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) ABC_tran_Xtn PF12848.7 AAAP01003875.1_39 - 1.7 8.7 4.1 6.1 6.9 0.0 2.8 3 0 0 3 3 3 0 ABC transporter EamA PF00892.20 AAAP01003875.1_40 - 2.3e-34 118.5 38.9 2.1e-19 70.0 11.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAAP01003875.1_40 - 3.6e-06 26.5 3.5 5.1e-06 26.1 3.5 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 AAAP01003875.1_40 - 1.2 8.3 5.7 2.3 7.3 2.1 2.2 2 0 0 2 2 2 0 UAA transporter family Amidase_2 PF01510.25 AAAP01003875.1_41 - 7.5e-32 110.4 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase TusA PF01206.17 AAAP01003875.1_42 - 2.8e-24 84.7 0.0 3e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 AAAP01003875.1_42 - 0.056 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Sulf_transp PF04143.14 AAAP01003875.1_43 - 2e-32 113.0 18.6 3.1e-32 112.4 18.6 1.2 1 0 0 1 1 1 1 Sulphur transport SoxY PF13501.6 AAAP01003875.1_44 - 1.5e-32 112.1 0.6 1.8e-32 111.8 0.0 1.4 2 0 0 2 2 2 1 Sulfur oxidation protein SoxY TAT_signal PF10518.9 AAAP01003875.1_44 - 0.018 14.9 7.2 0.046 13.6 7.2 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence SoxZ PF08770.11 AAAP01003875.1_45 - 2.4e-28 97.7 0.0 2.9e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ NIT PF08376.10 AAAP01003875.1_46 - 7.5e-52 177.1 7.8 7.5e-52 177.1 7.8 3.2 2 1 1 3 3 2 1 Nitrate and nitrite sensing MCPsignal PF00015.21 AAAP01003875.1_46 - 8.1e-33 113.6 44.4 5.2e-31 107.8 28.3 3.0 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003875.1_46 - 7.5e-08 32.6 1.7 5.1e-07 30.0 0.3 3.4 2 0 0 2 2 2 1 HAMP domain DUF948 PF06103.11 AAAP01003875.1_46 - 0.0096 16.2 28.6 0.81 10.0 0.4 6.3 3 1 2 5 5 5 1 Bacterial protein of unknown function (DUF948) Mur_ligase_C PF02875.21 AAAP01003875.1_46 - 0.057 13.7 1.0 0.38 11.0 0.2 2.8 1 1 1 2 2 2 0 Mur ligase family, glutamate ligase domain TMF_TATA_bd PF12325.8 AAAP01003875.1_46 - 0.064 13.5 0.3 0.064 13.5 0.3 4.3 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding Laminin_I PF06008.14 AAAP01003875.1_46 - 0.44 10.2 23.9 0.15 11.8 3.0 3.5 1 1 1 3 3 3 0 Laminin Domain I AAA_13 PF13166.6 AAAP01003875.1_46 - 1.5 7.3 10.2 0.56 8.8 6.1 1.9 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.12 AAAP01003875.1_46 - 1.6 8.8 15.0 1.5 8.9 2.7 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 AAAP01003875.1_46 - 2.4 8.0 5.2 4.4 7.2 0.2 3.5 3 1 1 4 4 4 0 Sec34-like family COG2 PF06148.11 AAAP01003875.1_46 - 4.9 7.3 10.9 11 6.1 1.3 4.0 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 AAAP01003875.1_46 - 6.1 7.0 7.8 39 4.4 0.5 3.7 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 AAAP01003875.1_46 - 6.8 6.7 26.7 0.48 10.4 3.8 4.6 2 1 2 4 4 4 0 Laminin Domain II BLOC1_2 PF10046.9 AAAP01003875.1_46 - 8.8 6.7 11.9 39 4.6 0.0 4.8 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 STAS PF01740.21 AAAP01003875.1_47 - 4.2e-08 32.8 0.0 5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AAAP01003875.1_47 - 3e-07 30.7 0.0 3.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 STAS domain ECH_1 PF00378.20 AAAP01003875.1_48 - 2e-55 187.8 0.2 2.3e-55 187.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003875.1_48 - 1.7e-29 103.4 0.8 7.4e-26 91.4 0.5 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase 4HBT PF03061.22 AAAP01003875.1_49 - 2e-11 44.0 0.1 3.4e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 AAAP01003875.1_49 - 1.7e-05 25.0 0.1 1.9e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 AAAP01003875.1_49 - 0.00064 20.1 0.1 0.00077 19.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily ydhR PF08803.11 AAAP01003875.1_50 - 1.3e-07 31.4 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR PAC1 PF16094.5 AAAP01003875.1_50 - 0.061 12.5 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 Biotin_lipoyl_2 PF13533.6 AAAP01003875.1_51 - 0.00038 20.2 0.3 0.075 12.9 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like TetR_C_24 PF17932.1 AAAP01003875.1_52 - 9.9e-35 119.3 0.1 1.8e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AAAP01003875.1_52 - 5e-12 45.4 1.1 8.8e-12 44.6 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 AAAP01003875.1_52 - 0.00054 20.0 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_29 PF17938.1 AAAP01003875.1_52 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AAAP01003875.1_52 - 0.0022 18.2 0.2 0.0073 16.5 0.2 1.9 1 1 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_27 PF17935.1 AAAP01003875.1_52 - 0.0026 17.8 0.3 0.013 15.6 0.1 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 AAAP01003875.1_52 - 0.055 13.6 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TetR_C_5 PF08360.11 AAAP01003875.1_52 - 0.17 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 QacR-like protein, C-terminal region ZnuA PF01297.17 AAAP01003875.1_52 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Response_reg PF00072.24 AAAP01003875.1_53 - 1.1e-21 77.1 0.0 1.5e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003875.1_53 - 4e-14 52.5 0.0 1.5e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAAP01003875.1_53 - 0.022 14.6 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 MarR family 7TMR-DISMED2 PF07696.11 AAAP01003875.1_54 - 5.6e-28 97.6 0.0 1.3e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 HATPase_c PF02518.26 AAAP01003875.1_54 - 2.4e-23 82.8 0.0 4.2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 7TMR-DISM_7TM PF07695.11 AAAP01003875.1_54 - 4.8e-22 78.9 8.6 7.9e-22 78.2 8.6 1.3 1 0 0 1 1 1 1 7TM diverse intracellular signalling PAS PF00989.25 AAAP01003875.1_54 - 1.2e-09 38.2 0.0 2.7e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AAAP01003875.1_54 - 6.6e-09 35.7 0.3 2.2e-08 34.0 0.3 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003875.1_54 - 3e-06 27.2 0.0 1.1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_9 PF13426.7 AAAP01003875.1_54 - 6e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AAAP01003875.1_54 - 0.0018 18.5 0.9 0.0031 17.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold SF-assemblin PF06705.11 AAAP01003875.1_54 - 0.9 8.8 4.5 0.94 8.8 2.6 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin TonB_dep_Rec PF00593.24 AAAP01003875.1_55 - 8.5e-15 55.6 18.8 1.7e-14 54.6 18.8 1.4 1 1 0 1 1 1 1 TonB dependent receptor HD PF01966.22 AAAP01003875.1_56 - 4e-17 62.6 0.0 7.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AAAP01003875.1_56 - 2.1e-15 56.7 0.5 6.8e-15 55.1 0.0 2.1 3 0 0 3 3 3 1 HD domain Response_reg PF00072.24 AAAP01003875.1_56 - 0.0019 18.3 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HDOD PF08668.12 AAAP01003875.1_56 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 HDOD domain adh_short_C2 PF13561.6 AAAP01003875.1_57 - 1.2e-58 198.5 3.0 1.4e-58 198.2 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003875.1_57 - 1.7e-54 184.3 2.1 2e-54 184.0 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003875.1_57 - 2e-17 63.7 0.3 2.8e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003875.1_57 - 0.00056 19.9 0.4 0.00077 19.4 0.4 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAAP01003875.1_57 - 0.0011 18.5 0.3 0.0029 17.1 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 AAAP01003875.1_57 - 0.014 16.3 0.3 3.5 8.7 0.0 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Thiolase_N PF00108.23 AAAP01003875.1_58 - 1.8e-100 335.6 9.2 2.3e-100 335.3 9.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 AAAP01003875.1_58 - 1.4e-50 170.1 4.8 1.5e-50 170.0 0.8 2.6 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 AAAP01003875.1_58 - 9.8e-06 25.3 4.5 0.00052 19.7 0.5 3.2 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain DUF2802 PF10975.8 AAAP01003875.1_58 - 0.059 13.5 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Abhydrolase_1 PF00561.20 AAAP01003875.1_59 - 1.3e-11 44.6 0.0 1.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003875.1_59 - 8.9e-07 29.7 6.8 8.9e-07 29.7 6.8 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family PhaC_N PF07167.13 AAAP01003875.1_59 - 1.5e-06 27.9 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Hydrolase_4 PF12146.8 AAAP01003875.1_59 - 1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 AAAP01003875.1_59 - 0.0001 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 AAAP01003875.1_59 - 0.00033 20.3 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3141 PF11339.8 AAAP01003875.1_59 - 0.0066 14.9 0.0 0.0093 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) Thioesterase PF00975.20 AAAP01003875.1_59 - 0.04 14.0 0.0 0.08 13.0 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 AAAP01003875.1_59 - 0.067 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.11 AAAP01003875.1_59 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal KA1 PF02149.19 AAAP01003875.1_59 - 0.6 10.0 2.3 1.5 8.7 0.3 2.2 2 0 0 2 2 2 0 Kinase associated domain 1 PHB_acc_N PF07879.11 AAAP01003875.1_60 - 4.4e-31 106.8 1.3 6.7e-31 106.2 1.3 1.3 1 0 0 1 1 1 1 PHB/PHA accumulation regulator DNA-binding domain PHB_acc PF05233.13 AAAP01003875.1_60 - 6.9e-16 58.0 6.5 8.5e-16 57.7 0.4 3.3 3 0 0 3 3 3 1 PHB accumulation regulatory domain LPP PF04728.13 AAAP01003875.1_60 - 2 8.9 6.1 3.3 8.2 1.7 2.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Peptidase_M16_C PF05193.21 AAAP01003875.1_61 - 3.3e-27 95.7 0.0 6.1e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAAP01003875.1_61 - 2.1e-05 24.5 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AAAP01003875.1_62 - 2.4e-29 102.7 0.0 4.3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AAAP01003875.1_62 - 2.5e-25 89.2 0.0 4.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3035 PF11233.8 AAAP01003875.1_63 - 1.2e-44 152.0 1.8 1.5e-44 151.7 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3035) Peptidase_A8 PF01252.18 AAAP01003875.1_64 - 1.9e-37 128.6 3.6 2.2e-37 128.4 3.6 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II tRNA-synt_1 PF00133.22 AAAP01003875.1_65 - 2.1e-184 614.2 0.0 2.5e-184 613.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AAAP01003875.1_65 - 1.1e-22 80.6 0.0 1.8e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AAAP01003875.1_65 - 5.1e-21 74.9 0.0 9.3e-11 41.1 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AAAP01003875.1_65 - 1.5e-07 31.1 0.0 0.00039 19.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AAAP01003875.1_65 - 8.4e-06 24.9 0.0 5.3e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.6 AAAP01003875.1_65 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 AAAP01003875.1_65 - 0.00072 19.4 3.4 0.0016 18.3 3.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FAD_syn PF06574.12 AAAP01003875.1_66 - 2.1e-50 170.7 0.1 2.9e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 AAAP01003875.1_66 - 5.5e-37 126.5 0.0 9e-37 125.8 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 AAAP01003875.1_66 - 0.014 15.6 0.0 0.052 13.7 0.1 2.0 2 0 0 2 2 2 0 Cytidylyltransferase-like MaoC_dehydratas PF01575.19 AAAP01003875.1_67 - 1.5e-26 92.3 0.2 1.9e-26 92.0 0.2 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AAAP01003875.1_67 - 3.5e-07 30.4 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 AAAP01003875.1_67 - 0.0045 17.3 0.0 0.0079 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Homoserine_dh PF00742.19 AAAP01003875.1_67 - 0.022 14.7 0.4 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase 4HBT PF03061.22 AAAP01003875.1_70 - 1.5e-10 41.3 0.1 1.9e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AAAP01003875.1_70 - 4.2e-10 40.2 0.0 5.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AAAP01003875.1_70 - 2.2e-05 23.9 0.0 0.035 13.4 0.0 2.0 2 0 0 2 2 2 2 Acyl-ACP thioesterase EamA PF00892.20 AAAP01003875.1_71 - 1.7e-35 122.2 34.8 1.3e-20 73.9 13.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AAAP01003875.1_71 - 0.00011 21.7 0.7 0.00011 21.7 0.7 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family SLC35F PF06027.12 AAAP01003875.1_71 - 0.04 13.4 0.5 0.057 12.9 0.5 1.2 1 0 0 1 1 1 0 Solute carrier family 35 LysR_substrate PF03466.20 AAAP01003875.1_72 - 1.8e-35 122.2 10.2 3.1e-35 121.4 10.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003875.1_72 - 8.6e-19 67.3 3.9 1.7e-18 66.3 3.9 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AAAP01003875.1_72 - 0.014 15.2 0.4 0.034 13.9 0.4 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AAAP01003875.1_72 - 0.028 14.3 0.1 0.098 12.6 0.1 1.9 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AAAP01003875.1_72 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AAAP01003875.1_72 - 0.14 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AAAP01003875.1_72 - 1.8 8.7 5.6 2.9 8.0 0.2 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Ferritin PF00210.24 AAAP01003875.1_73 - 8e-36 123.1 0.9 9.2e-36 122.9 0.9 1.0 1 0 0 1 1 1 1 Ferritin-like domain Ferritin PF00210.24 AAAP01003875.1_74 - 2.8e-36 124.5 4.9 3.4e-36 124.3 4.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF5446 PF17522.2 AAAP01003875.1_74 - 0.0043 17.2 1.1 0.16 12.2 0.1 2.7 2 1 1 3 3 3 1 Family of unknown function (DUF5446) Phage_TAC_12 PF12363.8 AAAP01003875.1_74 - 0.022 15.2 1.0 0.053 13.9 0.3 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Imm6 PF14434.6 AAAP01003875.1_74 - 0.054 13.4 0.4 0.098 12.6 0.4 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 HATPase_c PF02518.26 AAAP01003875.1_75 - 8.6e-24 84.2 0.0 1.9e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AAAP01003875.1_75 - 7e-15 55.2 1.9 4.4e-10 39.8 0.7 2.8 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AAAP01003875.1_75 - 2.2e-12 47.0 0.0 1.2e-06 28.5 0.0 2.7 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 AAAP01003875.1_75 - 3.8e-12 46.1 0.6 1.3e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01003875.1_75 - 2.8e-10 40.4 0.2 2.6e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AAAP01003875.1_75 - 1e-08 35.3 0.0 0.0021 18.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain dCache_1 PF02743.18 AAAP01003875.1_75 - 4e-08 33.4 0.0 9.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Cache domain PAS_8 PF13188.7 AAAP01003875.1_75 - 2.6e-07 30.5 0.0 0.016 15.3 0.0 2.8 2 0 0 2 2 2 2 PAS domain HATPase_c_5 PF14501.6 AAAP01003875.1_75 - 4.4e-05 23.3 0.0 7.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 GHKL domain DUF4381 PF14316.6 AAAP01003875.1_75 - 0.0075 16.5 0.5 0.0075 16.5 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) RCC1_2 PF13540.6 AAAP01003875.1_76 - 0.13 12.1 0.4 0.2 11.5 0.1 1.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Hom_end_hint PF05203.16 AAAP01003875.1_77 - 8.3e-11 42.3 0.0 1.2e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint Hint_2 PF13403.6 AAAP01003875.1_77 - 2.8e-05 24.4 0.0 0.00019 21.8 0.0 2.0 2 0 0 2 2 2 1 Hint domain Vint PF14623.6 AAAP01003875.1_77 - 0.00044 20.1 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Hint PF01079.20 AAAP01003875.1_77 - 0.00069 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Hint module AXH PF08517.12 AAAP01003875.1_77 - 0.00086 19.8 0.0 0.051 14.1 0.0 2.2 2 0 0 2 2 2 1 Ataxin-1 and HBP1 module (AXH) Intein_splicing PF14890.6 AAAP01003875.1_77 - 0.043 13.8 0.1 0.21 11.6 0.1 1.9 1 1 0 1 1 1 0 Intein splicing domain Response_reg PF00072.24 AAAP01003875.1_78 - 1.3e-22 80.1 0.1 2e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003875.1_78 - 3.7e-11 42.9 0.0 1.5e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Ribosomal_S21 PF01165.20 AAAP01003875.1_78 - 0.11 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 7TMR-DISMED2 PF07696.11 AAAP01003875.1_79 - 4.3e-20 72.1 0.0 7.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 7TMR-DISM extracellular 2 HATPase_c PF02518.26 AAAP01003875.1_79 - 1.7e-13 51.0 0.0 2.8e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 7TMR-DISM_7TM PF07695.11 AAAP01003875.1_79 - 2.5e-12 47.2 20.4 4.1e-12 46.4 20.4 1.3 1 0 0 1 1 1 1 7TM diverse intracellular signalling HisKA PF00512.25 AAAP01003875.1_79 - 3.7e-06 26.9 0.0 8.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003875.1_79 - 0.092 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DNA_pol3_chi PF04364.13 AAAP01003875.1_80 - 6.1e-38 130.1 0.0 6.9e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC JSRP PF15312.6 AAAP01003875.1_80 - 0.058 13.3 0.1 8.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Glycos_transf_2 PF00535.26 AAAP01003875.1_81 - 3.5e-18 66.0 0.0 4.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003875.1_81 - 3e-06 27.3 0.0 4.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF4141 PF13605.6 AAAP01003875.1_81 - 0.021 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Peptidase_M17 PF00883.21 AAAP01003875.1_82 - 1.4e-108 362.9 0.0 1.8e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AAAP01003875.1_82 - 8.9e-12 45.0 0.1 3.1e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Peptidase_M17 PF00883.21 AAAP01003875.1_83 - 1.3e-123 412.3 2.1 1.7e-123 411.9 2.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AAAP01003875.1_83 - 1.9e-25 89.1 1.7 6.6e-25 87.4 1.7 2.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain LPG_synthase_TM PF03706.13 AAAP01003875.1_84 - 2.1e-46 158.8 42.2 2.6e-46 158.6 42.2 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF2568 PF10823.8 AAAP01003875.1_84 - 0.028 14.7 1.0 0.028 14.7 1.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2568) Radical_SAM PF04055.21 AAAP01003875.1_85 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily DZR PF12773.7 AAAP01003875.1_85 - 0.031 14.3 0.1 0.13 12.3 0.0 2.0 2 1 0 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AAAP01003875.1_85 - 0.1 12.1 1.7 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AAAP01003875.1_85 - 0.34 10.4 4.5 6.7 6.3 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AAAP01003875.1_85 - 1.1 9.3 4.8 4.9 7.1 0.3 2.7 3 0 0 3 3 3 0 Nudix N-terminal Memo PF01875.17 AAAP01003875.1_87 - 9.9e-44 149.5 0.0 1.3e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein AMMECR1 PF01871.17 AAAP01003875.1_87 - 3e-43 147.3 0.0 4.7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 Ald_Xan_dh_C2 PF02738.18 AAAP01003875.1_88 - 2e-161 538.2 0.1 2.4e-161 538.0 0.1 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AAAP01003875.1_88 - 9.9e-21 74.2 0.0 2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Inositol_P PF00459.25 AAAP01003875.1_89 - 2.2e-50 171.7 0.0 2.6e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Acetyltransf_1 PF00583.25 AAAP01003875.1_90 - 8.1e-09 35.7 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AAAP01003875.1_90 - 0.0003 20.7 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AAAP01003875.1_90 - 0.00033 21.4 0.0 0.00049 20.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AAAP01003875.1_90 - 0.0027 18.1 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AAAP01003875.1_90 - 0.16 12.1 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase 4HB PF17947.1 AAAP01003875.1_90 - 0.26 11.4 0.7 20 5.3 0.0 2.3 2 0 0 2 2 2 0 Four helical bundle domain Sua5_yciO_yrdC PF01300.18 AAAP01003875.1_91 - 1.6e-56 190.6 0.0 2e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 AAAP01003875.1_91 - 2.1e-22 80.1 0.1 1e-21 77.9 0.1 2.0 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding PE PF00934.20 AAAP01003875.1_91 - 5.7 7.3 7.9 5.8 7.3 2.6 2.9 2 1 0 2 2 2 0 PE family FAD-oxidase_C PF02913.19 AAAP01003875.1_92 - 4e-57 193.7 0.0 5.9e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AAAP01003875.1_92 - 2.3e-36 124.6 1.1 4.6e-36 123.6 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro2_C5 PF18565.1 AAAP01003875.1_92 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 LptF_LptG PF03739.14 AAAP01003875.1_93 - 1.8e-66 224.4 6.3 2e-66 224.3 6.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG AraC_binding PF02311.19 AAAP01003875.1_93 - 0.17 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Phage-tail_3 PF13550.6 AAAP01003876.1_1 - 1.7e-24 86.5 0.0 2.3e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Putative phage tail protein Lambda_tail_I PF06805.12 AAAP01003876.1_2 - 1.1e-21 77.0 1.1 2.8e-21 75.6 1.1 1.8 1 0 0 1 1 1 1 Bacteriophage lambda tail assembly protein I NLPC_P60 PF00877.19 AAAP01003876.1_3 - 3.8e-06 26.9 0.0 4.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family DUF1833 PF08875.11 AAAP01003876.1_4 - 6.9e-71 236.7 0.1 7.8e-71 236.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1833) DUF736 PF05284.12 AAAP01003876.1_4 - 0.0091 15.9 0.0 0.069 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF736) FAM196 PF15265.6 AAAP01003876.1_10 - 1.2 8.6 13.1 1.4 8.3 13.1 1.0 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.13 AAAP01003876.1_10 - 3.5 7.5 18.7 4.3 7.2 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CiPC PF15800.5 AAAP01003876.1_10 - 3.7 7.2 13.9 5.1 6.7 13.9 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian ParD_antitoxin PF03693.14 AAAP01003876.1_12 - 4.8e-11 42.9 1.7 9.1e-11 42.0 1.2 1.7 1 1 1 2 2 2 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DUF4226 PF10774.9 AAAP01003876.1_12 - 0.015 15.5 0.9 0.018 15.3 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Fur_reg_FbpA PF13076.6 AAAP01003876.1_12 - 0.033 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein A Ribosomal_S7 PF00177.21 AAAP01003876.1_12 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Tape_meas_lam_C PF09718.10 AAAP01003876.1_14 - 4.4e-20 71.6 3.1 4.4e-20 71.6 3.1 2.8 3 0 0 3 3 3 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SHOCT PF09851.9 AAAP01003876.1_14 - 0.0097 15.6 2.5 0.0097 15.6 2.5 3.2 4 0 0 4 4 4 1 Short C-terminal domain BCSC_C PF05420.11 AAAP01003876.1_14 - 0.05 12.7 0.4 0.12 11.5 0.4 1.6 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) TPR_22 PF18833.1 AAAP01003876.1_14 - 0.051 13.7 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_H_T_join PF05521.11 AAAP01003876.1_22 - 0.071 13.6 0.1 0.079 13.5 0.1 1.2 1 0 0 1 1 1 0 Phage head-tail joining protein Gifsy-2 PF13856.6 AAAP01003876.1_22 - 0.14 12.5 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage Phage_cap_E PF03864.15 AAAP01003876.1_23 - 1.7e-92 310.2 0.3 2e-92 309.9 0.3 1.0 1 0 0 1 1 1 1 Phage major capsid protein E HDPD PF02924.14 AAAP01003876.1_24 - 4.7e-30 104.1 3.5 5.3e-30 103.9 3.5 1.0 1 0 0 1 1 1 1 Bacteriophage lambda head decoration protein D Peptidase_S49 PF01343.18 AAAP01003876.1_25 - 2.2e-31 108.9 0.1 3.5e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 AAAP01003876.1_25 - 0.14 12.1 0.3 1.2 9.0 0.0 2.2 1 1 0 2 2 2 0 Clp protease Phage_portal_2 PF05136.13 AAAP01003876.1_26 - 2.3e-104 349.4 0.1 4.5e-104 348.5 0.0 1.5 2 0 0 2 2 2 1 Phage portal protein, lambda family MerR_1 PF13411.6 AAAP01003876.1_26 - 0.0041 17.2 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 MerR HTH family regulatory protein PspA_IM30 PF04012.12 AAAP01003876.1_27 - 0.02 14.5 0.2 0.021 14.4 0.2 1.0 1 0 0 1 1 1 0 PspA/IM30 family Terminase_GpA PF05876.12 AAAP01003876.1_28 - 1.6e-211 703.8 1.8 1.8e-211 703.6 1.8 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.6 AAAP01003876.1_28 - 0.009 16.4 0.8 0.019 15.3 0.8 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 AAAP01003876.1_28 - 0.021 14.8 2.2 0.071 13.1 2.2 2.0 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AAAP01003876.1_28 - 0.25 11.5 1.0 23 5.2 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-HYPF PF07503.12 AAAP01003876.1_28 - 2.1 8.2 4.2 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 HypF finger HTH_50 PF18024.1 AAAP01003876.1_29 - 0.049 13.2 0.2 0.13 11.8 0.2 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF737 PF05300.11 AAAP01003876.1_29 - 0.14 12.5 1.0 0.16 12.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3489 PF11994.8 AAAP01003876.1_31 - 1.9e-31 107.9 0.4 3.6e-31 107.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3489) Bac_DNA_binding PF00216.21 AAAP01003876.1_33 - 1.8e-23 82.5 0.1 2e-23 82.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 AAAP01003876.1_33 - 0.016 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-HIG PF18291.1 AAAP01003876.1_33 - 0.02 15.0 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif N6_N4_Mtase PF01555.18 AAAP01003876.1_37 - 1.6e-16 60.8 0.1 1e-14 54.8 0.1 2.5 1 1 0 1 1 1 1 DNA methylase ParBc PF02195.18 AAAP01003876.1_37 - 6.8e-11 42.3 0.0 1.9e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain UPF0020 PF01170.18 AAAP01003876.1_37 - 0.017 14.8 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 AAAP01003876.1_37 - 0.039 13.7 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cupin_6 PF12852.7 AAAP01003876.1_37 - 0.098 12.4 0.2 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Cupin DNA_methylase PF00145.17 AAAP01003876.1_38 - 1.6e-40 139.5 0.0 7.6e-22 78.1 0.0 3.0 3 0 0 3 3 3 3 C-5 cytosine-specific DNA methylase DUF3277 PF11681.8 AAAP01003876.1_38 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) YozE_SAM_like PF06855.12 AAAP01003876.1_42 - 2.5e-06 27.5 0.0 2.9e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 YozE SAM-like fold DUF927 PF06048.11 AAAP01003876.1_43 - 4.8e-40 137.9 0.0 7.3e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF927) Toprim_3 PF13362.6 AAAP01003876.1_43 - 1.4e-23 83.1 0.2 6.7e-23 80.9 0.2 2.3 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AAAP01003876.1_43 - 0.0096 16.3 0.0 0.029 14.8 0.0 1.9 1 0 0 1 1 1 1 Toprim-like AAA_30 PF13604.6 AAAP01003876.1_43 - 0.089 12.5 2.3 0.26 11.0 2.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003876.1_44 - 8.6e-22 77.8 0.1 3e-21 76.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AAAP01003876.1_44 - 2.3e-19 68.9 0.1 5.2e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AAAP01003876.1_44 - 2.4e-12 47.4 0.0 6.6e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AAAP01003876.1_44 - 4.1e-08 33.2 0.0 0.0057 16.4 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 AAAP01003876.1_44 - 2.3e-05 24.7 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 AAAP01003876.1_44 - 6.4e-05 22.3 0.7 0.0088 15.3 0.2 2.8 2 1 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.6 AAAP01003876.1_44 - 0.0027 18.1 0.1 0.0084 16.5 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C PF13361.6 AAAP01003876.1_44 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain HTH_23 PF13384.6 AAAP01003876.1_45 - 0.014 15.2 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Terminase_5 PF06056.12 AAAP01003876.1_45 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Nudix_N_2 PF14803.6 AAAP01003876.1_45 - 4.1 7.4 5.6 20 5.2 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal HWE_HK PF07536.14 AAAP01003876.1_47 - 0.046 14.4 0.1 0.059 14.1 0.1 1.2 1 0 0 1 1 1 0 HWE histidine kinase MSA-2c PF12238.8 AAAP01003876.1_49 - 9.1 6.2 10.7 12 5.8 10.7 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c AAA_24 PF13479.6 AAAP01003876.1_50 - 1.9e-43 148.5 0.0 2.2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003876.1_50 - 0.0013 19.1 0.0 0.0065 16.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AAAP01003876.1_50 - 0.0018 18.7 0.0 0.0048 17.3 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AAAP01003876.1_50 - 0.0044 17.3 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAAP01003876.1_50 - 0.0053 17.3 0.1 0.012 16.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 AAAP01003876.1_50 - 0.014 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AAAP01003876.1_50 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AAAP01003876.1_50 - 0.076 13.6 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AAAP01003876.1_50 - 0.13 11.7 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AAAP01003876.1_50 - 0.14 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01003876.1_50 - 0.16 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 AAAP01003876.1_50 - 0.18 12.1 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AAAP01003876.1_50 - 0.21 10.7 0.0 0.67 9.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain PDEase_I_N PF08499.12 AAAP01003876.1_52 - 0.038 13.8 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal HTH_31 PF13560.6 AAAP01003876.1_53 - 2e-08 34.4 0.6 4.4e-08 33.4 0.6 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Peptidase_S24 PF00717.23 AAAP01003876.1_53 - 2.6e-06 27.3 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 AAAP01003876.1_53 - 9.9e-05 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003876.1_53 - 0.007 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003876.1_53 - 0.0081 16.6 0.0 0.018 15.5 0.0 1.5 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain DUF2924 PF11149.8 AAAP01003876.1_55 - 5.1e-52 175.8 0.0 5.8e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2924) Resolvase PF00239.21 AAAP01003876.1_56 - 5e-38 130.5 0.0 1e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 AAAP01003876.1_56 - 5.5e-15 55.6 1.0 1e-14 54.8 1.0 1.4 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 AAAP01003876.1_56 - 9.2e-10 38.9 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Recombinase Ogr_Delta PF04606.12 AAAP01003876.1_56 - 0.2 11.7 2.3 0.39 10.7 2.3 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger SoPB_HTH PF18090.1 AAAP01003876.1_57 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Centromere-binding protein HTH domain SpoVG PF04026.12 AAAP01003876.1_60 - 6.5e-06 26.3 0.0 9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 SpoVG IF3_C PF00707.22 AAAP01003876.1_61 - 8.2e-40 134.7 3.2 1.2e-39 134.1 3.2 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AAAP01003876.1_61 - 5.1e-29 100.4 0.0 1e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain tRNA-synt_2b PF00587.25 AAAP01003876.1_62 - 9.3e-42 143.0 0.0 1.6e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AAAP01003876.1_62 - 2e-19 69.5 2.7 6.1e-19 68.0 2.7 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 AAAP01003876.1_62 - 1.2e-13 50.9 0.0 2.3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF5555 PF17710.1 AAAP01003876.1_62 - 0.11 12.0 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5555) IPPT PF01715.17 AAAP01003876.1_62 - 0.15 11.9 0.5 0.79 9.5 0.1 2.1 2 0 0 2 2 2 0 IPP transferase Lipoprotein_15 PF03640.15 AAAP01003876.1_62 - 0.16 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function Glyco_transf_9 PF01075.17 AAAP01003876.1_63 - 6.6e-21 74.8 0.0 1.1e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_4 PF13439.6 AAAP01003876.1_64 - 5.6e-33 114.3 3.0 4.4e-28 98.4 2.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01003876.1_64 - 1.7e-27 96.0 0.0 2.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003876.1_64 - 2.9e-23 82.8 0.0 5.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003876.1_64 - 7.7e-20 71.9 16.1 2.9e-16 60.3 4.4 2.6 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AAAP01003876.1_64 - 2.7e-08 33.9 0.0 5.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 AAAP01003876.1_64 - 0.00011 22.6 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hydrolase_4 PF12146.8 AAAP01003876.1_65 - 3.6e-17 62.4 1.5 4e-12 45.9 0.7 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AAAP01003876.1_65 - 2.3e-14 54.5 1.9 3.1e-14 54.1 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003876.1_65 - 2.6e-10 40.4 0.8 4.7e-08 33.0 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold UPF0227 PF05728.12 AAAP01003876.1_65 - 3.8e-06 27.0 0.0 1.6e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 AAAP01003876.1_65 - 3.7e-05 23.3 0.0 8.6e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 AAAP01003876.1_65 - 0.00031 20.5 0.0 0.00077 19.2 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 AAAP01003876.1_65 - 0.00076 19.2 0.3 0.057 13.0 0.1 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Patatin PF01734.22 AAAP01003876.1_65 - 0.0023 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2920 PF11144.8 AAAP01003876.1_65 - 0.082 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 AAAP01003876.1_65 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 AAAP01003876.1_65 - 0.18 11.6 0.0 7.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase SpoIIE PF07228.12 AAAP01003876.1_68 - 9.9e-40 136.5 0.2 2e-39 135.5 0.2 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 AAAP01003876.1_68 - 9.4e-25 87.0 0.0 1.9e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_2 PF13185.6 AAAP01003876.1_68 - 3.6e-17 63.0 0.8 1.2e-16 61.3 0.2 2.1 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 AAAP01003876.1_68 - 7.7e-14 52.5 0.0 1.6e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAAP01003876.1_68 - 1e-07 32.3 0.0 2.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 AAAP01003876.1_68 - 0.063 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor STAS_2 PF13466.6 AAAP01003876.1_69 - 1.8e-19 69.8 0.5 2.3e-19 69.5 0.5 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003876.1_69 - 4e-17 61.9 0.0 4.4e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 STAS domain MlaE PF02405.16 AAAP01003876.1_70 - 1.4e-66 224.2 22.2 1.7e-66 223.9 22.2 1.1 1 0 0 1 1 1 1 Permease MlaE ABC_tran PF00005.27 AAAP01003876.1_71 - 2e-29 102.8 0.0 2.9e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003876.1_71 - 8.6e-06 25.8 0.5 0.039 13.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003876.1_71 - 0.0003 21.2 1.3 0.0018 18.7 1.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 AAAP01003876.1_71 - 0.0018 18.6 0.1 0.003 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 AAAP01003876.1_71 - 0.0021 17.7 0.1 0.0042 16.7 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AAAP01003876.1_71 - 0.0021 18.0 0.8 0.0037 17.2 0.8 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 AAAP01003876.1_71 - 0.0024 17.6 0.1 0.0036 17.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003876.1_71 - 0.0032 17.2 0.6 0.0059 16.3 0.6 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 AAAP01003876.1_71 - 0.0044 15.9 3.2 0.66 8.7 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class T2SSE PF00437.20 AAAP01003876.1_71 - 0.0052 15.9 0.3 0.009 15.1 0.3 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 AAAP01003876.1_71 - 0.0068 16.7 0.5 0.026 14.7 0.4 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 AAAP01003876.1_71 - 0.0084 16.0 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 AAAP01003876.1_71 - 0.016 15.0 0.4 0.074 12.8 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAAP01003876.1_71 - 0.016 15.4 0.6 0.043 14.1 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AAAP01003876.1_71 - 0.018 15.0 0.6 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 AAAP01003876.1_71 - 0.039 13.4 1.2 0.061 12.8 1.2 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Zeta_toxin PF06414.12 AAAP01003876.1_71 - 0.054 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AAAP01003876.1_71 - 0.065 13.1 0.5 0.065 13.1 0.5 1.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 AAAP01003876.1_71 - 0.072 13.0 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DLIC PF05783.11 AAAP01003876.1_71 - 0.078 11.8 0.3 0.16 10.8 0.3 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 AAAP01003876.1_71 - 0.1 12.2 0.3 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AAAP01003876.1_71 - 0.11 13.0 0.2 0.15 12.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AAAP01003876.1_71 - 0.12 11.4 1.0 0.35 9.8 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AAAP01003876.1_71 - 0.14 12.3 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 AAAP01003876.1_71 - 0.2 11.4 0.5 1 9.1 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 AAAP01003876.1_71 - 0.24 10.8 0.3 11 5.4 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 AAAP01003876.1_71 - 0.27 10.0 0.1 1.7 7.4 0.1 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein DAP3 PF10236.9 AAAP01003876.1_71 - 0.31 10.2 0.7 1 8.5 0.8 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 AAAP01003876.1_71 - 0.31 10.2 0.3 0.43 9.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MlaD PF02470.20 AAAP01003876.1_72 - 7.2e-12 45.4 0.0 1.9e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 MlaD protein FlgN PF05130.12 AAAP01003876.1_72 - 0.00023 21.7 2.3 0.00035 21.1 2.3 1.4 1 1 0 1 1 1 1 FlgN protein DUF948 PF06103.11 AAAP01003876.1_72 - 0.0039 17.4 8.1 0.51 10.6 0.0 4.1 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) DUF1351 PF07083.11 AAAP01003876.1_72 - 0.0067 16.2 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) Mce4_CUP1 PF11887.8 AAAP01003876.1_72 - 0.0071 15.8 3.1 0.016 14.7 2.9 1.5 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative BORCS6 PF10157.9 AAAP01003876.1_72 - 0.01 16.0 2.2 1.6 9.0 0.6 2.5 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 Apolipoprotein PF01442.18 AAAP01003876.1_72 - 0.011 15.6 1.1 0.02 14.7 1.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 AAAP01003876.1_72 - 0.014 15.4 10.0 0.021 14.9 4.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 AAAP01003876.1_72 - 0.016 15.3 2.5 0.075 13.1 0.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 AAAP01003876.1_72 - 0.038 14.0 0.9 0.22 11.5 0.1 2.3 1 1 1 2 2 2 0 Short coiled-coil protein Bacillus_HBL PF05791.11 AAAP01003876.1_72 - 0.041 13.7 3.3 0.28 11.0 1.5 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 AAAP01003876.1_72 - 0.046 13.9 1.1 0.078 13.2 1.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DASH_Duo1 PF08651.10 AAAP01003876.1_72 - 0.055 13.3 2.5 6.4 6.6 0.0 3.1 1 1 2 3 3 3 0 DASH complex subunit Duo1 Z1 PF10593.9 AAAP01003876.1_72 - 0.085 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Z1 domain Laminin_II PF06009.12 AAAP01003876.1_72 - 0.085 12.9 3.6 6.3 6.8 3.2 2.8 1 1 0 1 1 1 0 Laminin Domain II HWE_HK PF07536.14 AAAP01003876.1_72 - 0.24 12.1 3.4 1.9 9.3 0.2 2.7 2 1 1 3 3 3 0 HWE histidine kinase DUF4107 PF13389.6 AAAP01003876.1_72 - 0.32 11.1 1.1 0.98 9.6 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4107) DUF4407 PF14362.6 AAAP01003876.1_72 - 0.36 10.1 3.2 0.15 11.3 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_trans_aux PF03886.13 AAAP01003876.1_73 - 1.1e-12 47.9 0.2 1.3e-12 47.6 0.2 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component LPAM_1 PF08139.12 AAAP01003876.1_73 - 0.1 13.1 1.2 0.2 12.2 1.2 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site tRNA_U5-meth_tr PF05958.11 AAAP01003876.1_75 - 1.5e-13 50.5 0.0 2.1e-10 40.1 0.0 2.0 1 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 AAAP01003876.1_75 - 0.022 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 AAAP01003876.1_75 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB HPTransfase PF10090.9 AAAP01003876.1_76 - 3e-25 88.4 0.0 4.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain CheW PF01584.19 AAAP01003876.1_77 - 2.3e-32 111.5 5.0 2.6e-22 79.0 1.1 2.4 2 0 0 2 2 2 2 CheW-like domain Response_reg PF00072.24 AAAP01003876.1_77 - 5.4e-20 71.6 0.0 1.2e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 AAAP01003876.1_77 - 7.5e-17 61.4 0.0 2.4e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Hpt domain HATPase_c PF02518.26 AAAP01003876.1_77 - 1.2e-15 57.9 0.5 2.7e-15 56.8 0.5 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AAAP01003876.1_77 - 3.9e-15 56.0 2.2 1.1e-14 54.5 2.2 1.9 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain CheW PF01584.19 AAAP01003876.1_78 - 3.5e-27 94.7 0.1 3.9e-27 94.6 0.1 1.0 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AAAP01003876.1_79 - 5.4e-29 100.6 0.1 5.9e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain URO-D PF01208.17 AAAP01003876.1_79 - 0.063 12.4 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) CheB_methylest PF01339.17 AAAP01003876.1_80 - 4.6e-54 182.7 0.1 7.8e-54 181.9 0.1 1.4 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 AAAP01003876.1_80 - 1.6e-24 86.3 0.3 2.5e-24 85.6 0.3 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Nitro_FeMo-Co PF02579.17 AAAP01003876.1_80 - 0.17 12.3 0.1 0.38 11.1 0.1 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor CheR PF01739.18 AAAP01003876.1_81 - 7.4e-62 208.3 0.0 9e-62 208.0 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AAAP01003876.1_81 - 1.5e-09 37.4 0.1 2.7e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AAAP01003876.1_81 - 5.6e-08 33.4 0.0 1.4e-05 25.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003876.1_81 - 6.6e-08 33.2 0.0 8.7e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003876.1_81 - 2e-06 28.4 0.0 6.6e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003876.1_81 - 2.3e-06 27.5 0.0 3.3e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003876.1_81 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 AAAP01003876.1_81 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein PEPCK_GTP PF00821.18 AAAP01003876.1_81 - 0.18 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Ribosomal_L28 PF00830.19 AAAP01003876.1_82 - 6.7e-25 87.1 0.2 1.1e-24 86.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L28 family HSP33 PF01430.19 AAAP01003876.1_84 - 2.2e-73 247.0 0.0 2.5e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein NapD PF03927.13 AAAP01003876.1_84 - 0.0073 16.3 0.0 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 NapD protein OTCace_N PF02729.21 AAAP01003876.1_85 - 1.2e-48 164.9 0.0 1.6e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AAAP01003876.1_85 - 1.7e-47 161.4 0.0 2.9e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain TusA PF01206.17 AAAP01003876.1_85 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA Aminotran_3 PF00202.21 AAAP01003876.1_86 - 9.4e-114 380.2 0.0 1.2e-113 379.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ABC2_membrane PF01061.24 AAAP01003876.1_87 - 1e-28 100.2 18.2 1.5e-28 99.6 18.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AAAP01003876.1_87 - 1.7e-07 30.7 17.5 1.7e-07 30.7 17.5 1.5 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF92 PF01940.16 AAAP01003876.1_87 - 9.2 5.6 12.0 47 3.3 12.0 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF92 RecX PF02631.16 AAAP01003876.1_88 - 1e-19 71.2 0.1 1.2e-19 71.0 0.1 1.0 1 0 0 1 1 1 1 RecX family GAF_2 PF13185.6 AAAP01003876.1_89 - 0.00012 22.4 0.0 0.00014 22.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AAAP01003876.1_89 - 0.022 15.1 0.0 0.11 12.8 0.0 2.0 1 1 1 2 2 2 0 GAF domain GAF PF01590.26 AAAP01003876.1_89 - 0.025 15.2 0.0 0.032 14.8 0.0 1.3 1 1 0 1 1 1 0 GAF domain MCM_lid PF17855.1 AAAP01003876.1_89 - 0.14 12.6 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 MCM AAA-lid domain MS_channel PF00924.18 AAAP01003876.1_90 - 1.9e-39 135.4 0.5 1.9e-39 135.4 0.5 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel MscS_TM PF12794.7 AAAP01003876.1_90 - 0.0021 17.0 6.2 0.016 14.1 3.9 2.3 1 1 1 2 2 2 2 Mechanosensitive ion channel inner membrane domain 1 DUF2721 PF11026.8 AAAP01003876.1_90 - 0.0041 17.0 1.6 0.0041 17.0 1.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2721) LAL_C2 PF18603.1 AAAP01003876.1_90 - 0.0096 16.1 0.1 0.03 14.5 0.1 1.8 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 7tm_7 PF08395.12 AAAP01003876.1_90 - 0.056 12.7 0.2 0.09 12.0 0.2 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF2171 PF09939.9 AAAP01003876.1_90 - 0.074 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) DEC-1_N PF04625.13 AAAP01003876.1_90 - 0.96 8.4 4.4 1.3 7.9 4.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ArsC PF03960.15 AAAP01003876.1_91 - 2.3e-13 50.0 0.0 2.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AAAP01003876.1_91 - 0.00085 19.5 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin AbiEi_4 PF13338.6 AAAP01003876.1_91 - 0.13 12.4 0.2 6.3 7.0 0.0 3.0 3 2 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin OprF PF05736.11 AAAP01003876.1_92 - 0.0092 15.7 0.3 0.023 14.5 0.3 1.7 1 0 0 1 1 1 1 OprF membrane domain LID PF17916.1 AAAP01003876.1_92 - 0.039 13.6 0.2 0.083 12.6 0.2 1.5 1 0 0 1 1 1 0 LIM interaction domain (LID) MM_CoA_mutase PF01642.22 AAAP01003876.1_93 - 1.1e-59 202.3 2.5 1.5e-59 201.9 2.5 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 AAAP01003876.1_93 - 1.9e-16 60.2 0.4 4.9e-16 58.9 0.4 1.7 1 0 0 1 1 1 1 B12 binding domain DUF2236 PF09995.9 AAAP01003876.1_93 - 0.039 14.2 0.2 0.082 13.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) AAA_26 PF13500.6 AAAP01003877.1_1 - 1.2e-21 77.4 0.0 2e-21 76.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AAAP01003877.1_1 - 1.6e-17 63.7 0.0 1.8e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF45 PF01863.17 AAAP01003877.1_2 - 2.6e-49 168.1 0.0 3e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AAAP01003877.1_2 - 0.048 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 WLM domain MFS_1 PF07690.16 AAAP01003877.1_3 - 2.4e-43 148.4 48.1 2.4e-43 148.4 48.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AAAP01003877.1_3 - 7e-09 35.1 9.6 7e-09 35.1 9.6 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 AAAP01003877.1_3 - 7.3e-05 21.4 1.1 7.3e-05 21.4 1.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 AAAP01003877.1_3 - 0.00032 19.3 25.0 0.00041 18.9 25.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector 7TM_GPCR_Sri PF10327.9 AAAP01003877.1_3 - 0.013 14.7 1.4 0.039 13.2 1.1 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri UL42 PF17638.2 AAAP01003877.1_3 - 0.035 14.1 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 HCMV UL42 HATPase_c PF02518.26 AAAP01003877.1_4 - 7.5e-24 84.4 0.0 1.2e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003877.1_4 - 7.5e-17 61.1 2.8 1.6e-16 60.1 0.2 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AAAP01003877.1_4 - 3.9e-08 33.1 0.2 3e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AAAP01003877.1_4 - 1.4e-06 28.5 0.1 4.8e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AAAP01003877.1_4 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AAAP01003877.1_4 - 0.00029 20.8 0.0 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AAAP01003877.1_4 - 0.0073 16.2 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 1 GHKL domain AP_endonuc_2 PF01261.24 AAAP01003877.1_4 - 0.046 13.2 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Pentapeptide_3 PF13576.6 AAAP01003877.1_4 - 0.22 11.7 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) PTA_PTB PF01515.19 AAAP01003877.1_5 - 1.2e-87 294.2 0.1 1.8e-87 293.7 0.1 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase malic PF00390.19 AAAP01003877.1_5 - 1.1e-28 100.3 0.0 1.3e-26 93.5 0.0 2.5 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 AAAP01003877.1_5 - 1.3e-19 70.5 1.8 6.8e-19 68.1 1.8 2.2 2 1 0 2 2 2 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 AAAP01003877.1_5 - 0.00024 20.5 0.8 0.00047 19.5 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 AAAP01003877.1_5 - 0.0082 15.9 0.3 0.018 14.8 0.3 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DXP_synthase_N PF13292.6 AAAP01003877.1_5 - 0.18 11.0 0.2 0.39 9.9 0.2 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase YflT PF11181.8 AAAP01003877.1_6 - 0.017 15.6 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Heat induced stress protein YflT MutS_V PF00488.21 AAAP01003877.1_7 - 2.1e-83 279.0 0.0 4.2e-83 278.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AAAP01003877.1_7 - 1.7e-39 134.6 0.0 3e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 AAAP01003877.1_7 - 9.1e-38 130.4 0.4 2.2e-37 129.1 0.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 AAAP01003877.1_7 - 4.3e-21 75.6 0.0 9.9e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 AAAP01003877.1_7 - 7.3e-20 71.1 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 AAAP01003877.1_7 - 0.0032 17.1 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AAAP01003877.1_7 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gate PF07670.14 AAAP01003877.1_8 - 1.9e-05 24.9 14.8 4.7e-05 23.6 8.1 2.8 2 1 0 2 2 2 2 Nucleoside recognition EII-GUT PF03608.13 AAAP01003877.1_8 - 0.61 10.0 5.1 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 PTS system enzyme II sorbitol-specific factor Pyr_redox_2 PF07992.14 AAAP01003877.1_9 - 2.2e-17 63.2 0.0 3.5e-15 56.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 AAAP01003877.1_9 - 9.7e-05 22.1 1.6 0.00076 19.2 1.6 2.2 1 1 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K_oxygenase PF13434.6 AAAP01003877.1_9 - 0.0062 15.7 0.0 1.1 8.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AAAP01003877.1_9 - 0.025 13.7 0.3 6.1 5.8 0.1 2.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 AAAP01003877.1_9 - 0.057 12.7 0.2 0.16 11.2 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 AAAP01003877.1_9 - 0.12 12.7 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 AAAP01003877.1_9 - 0.15 12.5 0.1 0.92 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 AAAP01003877.1_9 - 0.34 11.5 1.3 54 4.4 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M23 PF01551.22 AAAP01003877.1_11 - 1.2e-26 92.7 0.0 2e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M23 Glyco_hydro_65C PF03633.15 AAAP01003877.1_11 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain adh_short_C2 PF13561.6 AAAP01003877.1_13 - 2.9e-41 141.6 4.5 4.4e-41 141.0 4.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003877.1_13 - 2.4e-38 131.6 1.3 3.9e-38 130.9 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Aldolase_II PF00596.21 AAAP01003877.1_13 - 4.5e-30 105.0 0.0 6.8e-27 94.6 0.0 2.8 2 1 0 2 2 2 2 Class II Aldolase and Adducin N-terminal domain KR PF08659.10 AAAP01003877.1_13 - 1.5e-08 34.7 0.8 2.8e-08 33.9 0.8 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003877.1_13 - 0.00018 21.0 1.8 0.00025 20.6 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAAP01003877.1_13 - 0.011 14.7 0.2 0.017 14.2 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003877.1_13 - 0.021 14.0 1.0 0.034 13.2 1.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 AAAP01003877.1_13 - 0.022 14.6 1.2 0.047 13.6 1.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BBE PF08031.12 AAAP01003877.1_13 - 0.036 14.2 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Polysacc_synt_2 PF02719.15 AAAP01003877.1_13 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HI0933_like PF03486.14 AAAP01003877.1_13 - 0.18 10.5 2.4 0.27 9.9 2.0 1.5 2 0 0 2 2 2 0 HI0933-like protein NmrA PF05368.13 AAAP01003877.1_13 - 0.23 11.0 2.1 0.42 10.1 2.1 1.3 1 0 0 1 1 1 0 NmrA-like family Rhodanese PF00581.20 AAAP01003877.1_15 - 6.7e-08 33.0 0.0 8.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain ABC_tran PF00005.27 AAAP01003877.1_16 - 2.1e-29 102.8 0.0 3.2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003877.1_16 - 1.8e-11 44.4 0.6 2.1e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003877.1_16 - 3.9e-05 24.1 0.7 7.2e-05 23.2 0.7 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAAP01003877.1_16 - 0.011 15.1 0.1 4 6.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 AAAP01003877.1_16 - 0.038 13.7 0.0 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AAAP01003877.1_16 - 0.04 14.2 0.0 0.081 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AAAP01003877.1_16 - 0.041 13.6 0.8 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AAAP01003877.1_16 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AAAP01003877.1_16 - 0.08 13.4 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AAAP01003877.1_16 - 0.082 12.5 1.7 0.75 9.3 1.7 2.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AAAP01003877.1_16 - 0.085 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AAAP01003877.1_16 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RecA PF00154.21 AAAP01003877.1_16 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_19 PF13245.6 AAAP01003877.1_16 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003877.1_16 - 0.17 12.1 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain CbiQ PF02361.16 AAAP01003877.1_17 - 1e-39 136.4 7.0 1.4e-39 136.0 7.0 1.1 1 0 0 1 1 1 1 Cobalt transport protein CbiN PF02553.15 AAAP01003877.1_18 - 1.5e-20 72.9 0.1 1.8e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Cobalt transport protein component CbiN DUF4229 PF14012.6 AAAP01003877.1_18 - 0.14 12.3 1.1 29 4.8 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) CbiM PF01891.16 AAAP01003877.1_19 - 3.3e-44 151.2 21.8 3.7e-44 151.0 21.8 1.0 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region Response_reg PF00072.24 AAAP01003877.1_20 - 2.8e-28 98.3 0.2 4.2e-28 97.8 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003877.1_20 - 2.3e-22 78.9 0.0 5.2e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_11 PF08279.12 AAAP01003877.1_20 - 0.087 12.8 0.4 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 HTH domain Stimulus_sens_1 PF13756.6 AAAP01003877.1_21 - 9.7e-31 106.6 0.2 3.3e-30 104.9 0.2 2.0 1 0 0 1 1 1 1 Stimulus-sensing domain HATPase_c PF02518.26 AAAP01003877.1_21 - 3.3e-22 79.1 0.0 8.5e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sensor_TM1 PF13755.6 AAAP01003877.1_21 - 1.5e-17 63.0 0.1 4.1e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Sensor N-terminal transmembrane domain HisKA PF00512.25 AAAP01003877.1_21 - 9.6e-13 48.0 0.4 9.6e-13 48.0 0.4 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AAAP01003877.1_21 - 2e-11 44.1 2.4 7.7e-11 42.2 0.3 2.7 2 0 0 2 2 2 1 HAMP domain VWA_3 PF13768.6 AAAP01003877.1_21 - 0.0027 17.7 0.4 0.0087 16.0 0.1 1.9 3 0 0 3 3 3 1 von Willebrand factor type A domain HATPase_c_2 PF13581.6 AAAP01003877.1_21 - 0.013 15.5 0.3 0.043 13.8 0.0 2.0 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain HPTransfase PF10090.9 AAAP01003877.1_21 - 0.06 13.1 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 AAAP01003877.1_21 - 0.22 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S49_N PF08496.10 AAAP01003877.1_22 - 0.42 10.7 7.4 0.75 9.8 7.4 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal V_ATPase_I PF01496.19 AAAP01003877.1_22 - 1.2 6.9 3.8 1.3 6.8 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 AAAP01003877.1_22 - 3.3 6.2 13.6 3.3 6.1 13.6 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 AAAP01003877.1_22 - 5.1 5.7 7.1 5.6 5.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin KfrA_N PF11740.8 AAAP01003877.1_22 - 6.4 7.5 12.8 1.8 9.3 1.0 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term AAA_11 PF13086.6 AAAP01003877.1_22 - 7.4 6.3 11.1 8.5 6.1 11.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 AAAP01003877.1_22 - 10 5.4 10.2 12 5.2 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ysc84 PF04366.12 AAAP01003877.1_23 - 3.6e-25 88.2 1.0 3.6e-25 88.2 1.0 1.8 2 1 0 2 2 2 1 Las17-binding protein actin regulator Fer2_2 PF01799.20 AAAP01003877.1_24 - 1.1e-23 83.1 0.1 1.6e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 AAAP01003877.1_24 - 9.5e-09 35.1 0.1 2.3e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AAAP01003877.1_24 - 1.9e-05 24.6 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AAAP01003877.1_24 - 0.021 14.6 3.0 0.063 13.1 3.0 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ald_Xan_dh_C2 PF02738.18 AAAP01003877.1_25 - 2.8e-66 224.2 0.6 6.6e-32 110.7 0.0 3.0 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase TAT_signal PF10518.9 AAAP01003877.1_25 - 0.0092 15.8 0.2 0.0092 15.8 0.2 3.6 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence Ald_Xan_dh_C PF01315.22 AAAP01003877.1_25 - 0.026 14.9 0.0 0.074 13.4 0.0 1.9 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Cytochrom_C_asm PF01578.20 AAAP01003877.1_26 - 2e-31 109.4 14.2 2e-31 109.4 14.2 1.4 2 0 0 2 2 2 1 Cytochrome C assembly protein CcmD PF04995.14 AAAP01003877.1_27 - 1.5e-11 44.2 4.5 2.6e-11 43.4 4.5 1.4 1 1 0 1 1 1 1 Heme exporter protein D (CcmD) RIC3 PF15361.6 AAAP01003877.1_27 - 0.0092 16.4 0.0 0.0096 16.3 0.0 1.0 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 CcmE PF03100.15 AAAP01003877.1_28 - 2.4e-46 156.9 0.0 2.8e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 CcmE DUF2061 PF09834.9 AAAP01003877.1_28 - 3.2 8.3 4.2 20 5.8 0.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) CcmF_C PF16327.5 AAAP01003877.1_29 - 9.5e-117 389.9 5.1 9.5e-117 389.9 5.1 2.1 3 0 0 3 3 3 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 AAAP01003877.1_29 - 1.7e-53 181.5 16.2 1.7e-53 181.5 16.2 2.2 2 0 0 2 2 2 1 Cytochrome C assembly protein ResB PF05140.14 AAAP01003877.1_29 - 0.094 11.4 0.3 11 4.6 0.0 2.3 2 0 0 2 2 2 0 ResB-like family Redoxin PF08534.10 AAAP01003877.1_30 - 1.8e-08 34.2 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AAAP01003877.1_30 - 4.3e-05 23.4 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 AAAP01003877.1_30 - 0.097 12.7 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin CcmH PF03918.14 AAAP01003877.1_31 - 6.6e-54 181.1 0.0 7.6e-54 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein TPR_2 PF07719.17 AAAP01003877.1_32 - 4.3e-11 42.0 1.1 1.4e-06 28.0 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003877.1_32 - 1.1e-08 34.6 0.0 0.0026 17.4 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 AAAP01003877.1_32 - 1.7e-08 34.0 0.4 4.6e-07 29.5 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003877.1_32 - 5.7e-08 33.3 9.1 0.00018 22.1 0.1 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003877.1_32 - 4.4e-07 30.2 15.4 1.5e-05 25.4 1.4 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003877.1_32 - 3.8e-06 26.3 2.5 1e-05 24.9 2.5 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003877.1_32 - 1.5e-05 24.6 0.2 7.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003877.1_32 - 1.6e-05 25.3 10.9 0.033 14.7 0.6 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003877.1_32 - 1.9e-05 25.0 9.6 0.0027 18.2 0.2 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003877.1_32 - 4.7e-05 23.5 0.0 0.071 13.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003877.1_32 - 0.0017 18.3 3.3 0.23 11.6 0.5 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 AAAP01003877.1_32 - 0.0057 17.1 2.0 0.0057 17.1 2.0 2.4 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 AAAP01003877.1_32 - 0.0068 16.2 1.8 0.077 12.9 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003877.1_32 - 0.0084 16.4 7.1 0.033 14.5 1.7 3.4 2 2 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.12 AAAP01003877.1_32 - 0.013 15.2 0.0 0.97 9.2 0.0 2.2 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4919 PF16266.5 AAAP01003877.1_32 - 0.022 14.7 0.0 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) ANAPC3 PF12895.7 AAAP01003877.1_32 - 0.085 13.1 0.0 18 5.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 AAAP01003877.1_32 - 0.21 12.3 0.3 0.21 12.3 0.3 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat CcmB PF03379.13 AAAP01003877.1_33 - 3.7e-76 255.4 27.4 4.2e-76 255.2 27.4 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 AAAP01003877.1_33 - 0.0016 17.9 7.1 0.0018 17.7 6.9 1.3 1 1 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 AAAP01003877.1_34 - 6.6e-25 88.2 0.0 8.6e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003877.1_34 - 5.9e-10 39.5 0.0 3.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003877.1_34 - 1.1e-09 38.1 0.1 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AAAP01003877.1_34 - 7.4e-05 22.4 0.2 0.00015 21.5 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AAAP01003877.1_34 - 0.00014 22.3 0.3 0.00024 21.6 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AAAP01003877.1_34 - 0.0036 17.1 0.0 0.0072 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AAAP01003877.1_34 - 0.012 16.2 0.1 0.017 15.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AAAP01003877.1_34 - 0.029 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 AAAP01003877.1_34 - 0.033 14.2 0.2 0.072 13.1 0.2 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2813 PF11398.8 AAAP01003877.1_34 - 0.044 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Mg_chelatase PF01078.21 AAAP01003877.1_34 - 0.05 13.0 0.2 0.066 12.6 0.2 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AAAP01003877.1_34 - 0.071 13.0 0.5 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 AAAP01003877.1_34 - 0.093 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 AAAP01003877.1_34 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AAAP01003877.1_34 - 0.21 12.0 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 AAAP01003877.1_34 - 0.24 10.3 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain DUF748 PF05359.11 AAAP01003877.1_35 - 1.3e-25 90.3 3.3 3.8e-17 62.9 0.0 4.8 3 2 1 5 5 5 2 Domain of Unknown Function (DUF748) AsmA PF05170.14 AAAP01003877.1_35 - 2.3e-05 23.4 0.0 6.7e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 AsmA family OmpA PF00691.20 AAAP01003877.1_35 - 0.0058 17.0 0.0 0.037 14.4 0.0 2.2 1 1 0 1 1 1 1 OmpA family GTP_EFTU PF00009.27 AAAP01003877.1_36 - 5.3e-53 179.4 0.0 7.5e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AAAP01003877.1_36 - 1.1e-19 70.2 0.0 2.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AAAP01003877.1_36 - 2.5e-11 43.8 0.2 1.1e-10 41.7 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAAP01003877.1_36 - 1.3e-06 28.5 0.1 2.6e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 AAAP01003877.1_36 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 AAAP01003877.1_36 - 0.055 12.8 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 AAAP01003877.1_36 - 0.12 11.9 0.0 0.77 9.3 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B EFG_II PF14492.6 AAAP01003877.1_36 - 0.13 12.3 0.1 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Elongation Factor G, domain II PfkB PF00294.24 AAAP01003877.1_37 - 5.2e-43 147.5 0.4 6.6e-43 147.1 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase EI24 PF07264.11 AAAP01003877.1_38 - 2.4e-24 86.5 16.5 2.8e-24 86.3 16.5 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SpoIIM PF01944.17 AAAP01003877.1_38 - 0.18 11.8 14.9 0.6 10.1 5.9 2.3 1 1 1 2 2 2 0 Stage II sporulation protein M FCD PF07729.12 AAAP01003877.1_40 - 1.6e-27 96.4 14.2 3e-27 95.5 14.2 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01003877.1_40 - 2.1e-16 59.3 0.4 8.1e-16 57.4 0.0 2.2 3 0 0 3 3 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 AAAP01003877.1_40 - 4.1e-08 32.6 0.0 8.1e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AAAP01003877.1_40 - 1e-07 31.8 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 AAAP01003877.1_40 - 4.8e-06 26.3 0.0 2e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AAAP01003877.1_40 - 2.6e-05 24.0 0.1 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 AAAP01003877.1_40 - 0.00015 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 AAAP01003877.1_40 - 0.00044 20.0 2.0 0.016 15.0 0.0 3.2 3 1 0 3 3 3 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 AAAP01003877.1_40 - 0.00067 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 AAAP01003877.1_40 - 0.0014 18.6 0.0 0.0048 16.9 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix MarR PF01047.22 AAAP01003877.1_40 - 0.0023 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AAAP01003877.1_40 - 0.0037 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_1 PF00126.27 AAAP01003877.1_40 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_CodY PF08222.11 AAAP01003877.1_40 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_IclR PF09339.10 AAAP01003877.1_40 - 0.016 15.0 0.0 0.062 13.1 0.0 2.0 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 AAAP01003877.1_40 - 0.035 14.2 0.0 0.3 11.2 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AAAP01003877.1_40 - 0.051 13.7 2.3 0.086 13.0 0.0 2.5 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_41 PF14502.6 AAAP01003877.1_40 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 AAAP01003877.1_40 - 0.055 13.3 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain Rrf2 PF02082.20 AAAP01003877.1_40 - 0.069 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HSCB_C PF07743.13 AAAP01003877.1_40 - 0.092 13.3 4.6 0.074 13.5 2.2 2.0 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain HTH_36 PF13730.6 AAAP01003877.1_40 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain WXG100 PF06013.12 AAAP01003877.1_40 - 0.1 12.9 1.8 0.17 12.1 0.9 1.9 2 0 0 2 2 1 0 Proteins of 100 residues with WXG Halo_GVPC PF05465.13 AAAP01003877.1_40 - 3.3 8.1 6.3 0.49 10.7 1.0 2.2 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Na_sulph_symp PF00939.19 AAAP01003877.1_41 - 2.8e-27 95.9 26.6 3.7e-27 95.5 26.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 AAAP01003877.1_41 - 2e-12 47.0 32.8 2e-12 47.0 32.8 1.8 1 1 2 3 3 3 2 Citrate transporter TSC22 PF01166.18 AAAP01003877.1_42 - 8e-06 26.1 0.5 0.08 13.3 0.1 2.5 2 0 0 2 2 2 2 TSC-22/dip/bun family DUF2786 PF10979.8 AAAP01003877.1_42 - 0.00015 21.6 0.6 0.00015 21.6 0.6 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF2786) Cnn_1N PF07989.11 AAAP01003877.1_42 - 0.00025 21.2 1.4 0.0011 19.1 0.1 2.1 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 YabA PF06156.13 AAAP01003877.1_42 - 0.00027 21.5 5.6 0.3 11.8 0.3 3.0 1 1 2 3 3 3 2 Initiation control protein YabA NRBF2 PF08961.10 AAAP01003877.1_42 - 0.0009 18.9 2.9 0.52 9.9 0.0 2.3 2 0 0 2 2 2 2 Nuclear receptor-binding factor 2, autophagy regulator HAUS-augmin3 PF14932.6 AAAP01003877.1_42 - 0.0011 18.6 5.3 0.17 11.5 0.0 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 HALZ PF02183.18 AAAP01003877.1_42 - 0.0017 18.5 6.8 0.023 14.9 0.3 3.5 3 0 0 3 3 3 1 Homeobox associated leucine zipper Leu_zip PF15294.6 AAAP01003877.1_42 - 0.0029 17.2 1.4 0.0051 16.4 1.4 1.4 1 1 0 1 1 1 1 Leucine zipper ZapB PF06005.12 AAAP01003877.1_42 - 0.0046 17.4 11.3 0.57 10.7 1.5 3.2 1 1 2 3 3 3 2 Cell division protein ZapB MCC-bdg_PDZ PF10506.9 AAAP01003877.1_42 - 0.005 16.8 2.5 4 7.5 0.1 3.7 2 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 AAAP01003877.1_42 - 0.0073 16.5 1.3 0.033 14.4 0.3 2.0 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF3426 PF11906.8 AAAP01003877.1_42 - 0.0087 16.2 0.2 0.015 15.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) bZIP_1 PF00170.21 AAAP01003877.1_42 - 0.012 15.7 3.4 3.6 7.8 0.2 2.8 2 1 0 2 2 2 0 bZIP transcription factor ATG16 PF08614.11 AAAP01003877.1_42 - 0.012 15.8 10.7 0.034 14.4 10.7 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 AAAP01003877.1_42 - 0.014 15.8 3.3 0.22 12.0 0.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) betaPIX_CC PF16523.5 AAAP01003877.1_42 - 0.016 15.0 0.4 0.061 13.2 0.0 2.1 2 1 1 3 3 2 0 betaPIX coiled coil PRKG1_interact PF15898.5 AAAP01003877.1_42 - 0.018 15.9 5.6 0.93 10.4 3.4 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain K-box PF01486.17 AAAP01003877.1_42 - 0.023 14.9 0.8 7 6.9 0.0 2.7 2 1 0 2 2 2 0 K-box region GAS PF13851.6 AAAP01003877.1_42 - 0.034 13.5 6.8 0.034 13.5 2.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4795 PF16043.5 AAAP01003877.1_42 - 0.035 13.7 0.1 0.082 12.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FUSC PF04632.12 AAAP01003877.1_42 - 0.048 12.2 13.0 0.058 11.9 13.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MAD PF05557.13 AAAP01003877.1_42 - 0.053 11.9 5.1 0.12 10.7 1.5 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF3450 PF11932.8 AAAP01003877.1_42 - 0.054 12.8 4.8 0.41 9.9 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 AAAP01003877.1_42 - 0.059 12.7 6.2 0.073 12.4 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YscO PF07321.12 AAAP01003877.1_42 - 0.065 13.2 8.5 0.039 13.9 2.8 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO ACCA PF03255.14 AAAP01003877.1_42 - 0.067 13.1 0.6 0.099 12.5 0.6 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-F_leu_zip PF10473.9 AAAP01003877.1_42 - 0.067 13.2 8.1 2.2 8.3 4.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 AAAP01003877.1_42 - 0.072 13.1 6.7 0.19 11.8 6.7 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CtIP_N PF10482.9 AAAP01003877.1_42 - 0.088 12.9 2.9 0.99 9.5 0.1 2.5 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Uso1_p115_C PF04871.13 AAAP01003877.1_42 - 0.091 13.1 5.6 0.77 10.1 1.7 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 AAAP01003877.1_42 - 0.096 12.8 10.3 39 4.3 0.1 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 AAAP01003877.1_42 - 0.1 12.4 7.1 0.79 9.5 7.1 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Nnf1 PF03980.14 AAAP01003877.1_42 - 0.11 12.9 8.1 2.6 8.5 5.2 2.3 2 0 0 2 2 2 0 Nnf1 APG6_N PF17675.1 AAAP01003877.1_42 - 0.11 13.0 8.5 9.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region SOGA PF11365.8 AAAP01003877.1_42 - 0.15 13.2 3.5 0.38 11.9 1.3 2.1 1 1 1 2 2 2 0 Protein SOGA Herpes_BLRF2 PF05812.12 AAAP01003877.1_42 - 0.16 12.1 2.1 5 7.3 0.3 2.7 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein DASH_Dam1 PF08653.10 AAAP01003877.1_42 - 0.16 11.8 0.7 9.6 6.1 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 GIDA_assoc PF13932.6 AAAP01003877.1_42 - 0.16 12.1 1.7 0.22 11.7 1.7 1.1 1 0 0 1 1 1 0 GidA associated domain TAN PF11640.8 AAAP01003877.1_42 - 0.17 12.0 1.5 0.36 10.9 1.5 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DivIC PF04977.15 AAAP01003877.1_42 - 0.19 11.5 5.9 8.9 6.2 0.0 3.2 2 1 1 3 3 3 0 Septum formation initiator CASP_C PF08172.12 AAAP01003877.1_42 - 0.24 10.7 2.6 7 5.9 0.2 2.1 2 0 0 2 2 2 0 CASP C terminal DUF4201 PF13870.6 AAAP01003877.1_42 - 0.24 11.1 3.7 3.8 7.2 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 AAAP01003877.1_42 - 0.25 10.2 4.3 0.62 8.9 4.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 AAAP01003877.1_42 - 0.26 11.4 7.0 4.1 7.5 0.0 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation FlaC_arch PF05377.11 AAAP01003877.1_42 - 0.29 11.6 1.6 2.1 8.8 0.3 2.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 AAAP01003877.1_42 - 0.32 10.9 2.9 0.26 11.2 0.5 2.1 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region Spectrin PF00435.21 AAAP01003877.1_42 - 0.34 11.4 5.1 0.63 10.6 3.1 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF3584 PF12128.8 AAAP01003877.1_42 - 0.36 8.3 5.5 0.44 8.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.12 AAAP01003877.1_42 - 0.36 8.9 5.4 0.73 7.9 5.4 1.4 1 1 0 1 1 1 0 HOOK protein GIT_CC PF16559.5 AAAP01003877.1_42 - 0.42 10.5 2.8 6.3 6.8 0.2 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4349 PF14257.6 AAAP01003877.1_42 - 0.44 9.9 6.1 0.31 10.5 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) UPF0449 PF15136.6 AAAP01003877.1_42 - 0.47 10.9 2.7 3.9 8.0 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2205 PF10224.9 AAAP01003877.1_42 - 0.49 10.4 5.7 7.7 6.6 0.3 2.6 2 1 1 3 3 3 0 Short coiled-coil protein SlyX PF04102.12 AAAP01003877.1_42 - 0.57 10.8 10.0 2.8 8.6 0.2 3.7 1 1 2 3 3 3 0 SlyX Prefoldin_2 PF01920.20 AAAP01003877.1_42 - 0.68 9.9 3.0 15 5.6 0.1 2.8 2 1 1 3 3 3 0 Prefoldin subunit HAP1_N PF04849.13 AAAP01003877.1_42 - 0.8 8.9 7.6 2.3 7.3 2.4 2.2 1 1 0 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 AAAP01003877.1_42 - 0.9 10.0 6.0 0.7 10.3 2.9 1.9 1 1 1 2 2 2 0 Fez1 DUF1192 PF06698.11 AAAP01003877.1_42 - 1.6 8.8 0.0 1.6 8.8 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.15 AAAP01003877.1_42 - 1.9 8.6 10.8 1.7 8.8 0.6 3.4 4 0 0 4 4 3 0 Basic region leucine zipper Spc24 PF08286.11 AAAP01003877.1_42 - 2 8.7 6.2 21 5.4 2.0 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DHR10 PF18595.1 AAAP01003877.1_42 - 2 8.5 11.8 8.9 6.4 11.2 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 AAAP01003877.1_42 - 2.3 8.3 5.1 18 5.4 5.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 AAAP01003877.1_42 - 3.3 6.2 4.5 7.4 5.0 4.4 1.3 1 1 0 1 1 1 0 Macoilin family ADIP PF11559.8 AAAP01003877.1_42 - 3.8 7.6 9.3 14 5.7 4.0 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding COMP PF11598.8 AAAP01003877.1_42 - 5.9 7.5 7.0 0.35 11.4 1.0 2.0 3 0 0 3 3 1 0 Cartilage oligomeric matrix protein Fer4_18 PF13746.6 AAAP01003877.1_43 - 1.7e-39 134.5 5.9 5.2e-39 133.0 5.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AAAP01003877.1_43 - 1.9e-28 99.1 0.0 3.1e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_9 PF13187.6 AAAP01003877.1_43 - 2.6e-08 33.9 7.8 1.9e-05 24.8 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003877.1_43 - 3e-08 34.1 6.8 9.2e-05 23.0 1.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_5 PF12801.7 AAAP01003877.1_43 - 1.4e-07 31.4 4.6 1.4e-07 31.4 4.6 3.4 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003877.1_43 - 1.1e-06 29.1 7.6 0.00029 21.3 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003877.1_43 - 4.3e-05 23.9 7.5 0.011 16.1 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AAAP01003877.1_43 - 0.00055 20.2 19.5 0.048 14.2 4.2 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4 PF00037.27 AAAP01003877.1_43 - 0.00097 18.9 22.3 0.0039 16.9 3.7 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003877.1_43 - 0.0013 18.8 14.5 0.011 15.9 12.8 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003877.1_43 - 0.0018 18.2 20.6 0.005 16.8 3.6 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain EMP70 PF02990.16 AAAP01003877.1_43 - 0.066 11.9 1.2 0.13 11.0 1.2 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 Fer4_6 PF12837.7 AAAP01003877.1_43 - 0.2 11.8 21.0 0.19 11.8 5.0 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003877.1_43 - 0.38 11.8 24.1 0.22 12.6 4.9 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 AAAP01003877.1_43 - 0.46 11.5 18.0 0.43 11.6 4.9 3.2 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AAAP01003877.1_43 - 0.76 9.9 18.7 3.5 7.8 16.0 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003877.1_43 - 1.8 9.1 14.0 1.5 9.4 1.6 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I HAGH_C PF16123.5 AAAP01003877.1_44 - 2.6e-25 88.7 0.0 4.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AAAP01003877.1_44 - 1.2e-17 64.6 5.1 7e-17 62.1 5.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4177 PF13783.6 AAAP01003877.1_44 - 0.17 12.2 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Lactamase_B_2 PF12706.7 AAAP01003877.1_44 - 0.43 10.1 3.4 1.5 8.3 3.4 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Methyltransf_11 PF08241.12 AAAP01003877.1_45 - 1.7e-07 31.8 0.0 3.6e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003877.1_45 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003877.1_45 - 0.001 19.7 0.0 0.0023 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003877.1_45 - 0.021 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 AAAP01003877.1_45 - 0.036 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.6 AAAP01003877.1_45 - 0.046 13.5 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AAAP01003877.1_45 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 AAAP01003877.1_45 - 0.15 12.8 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.27 AAAP01003877.1_46 - 2e-47 161.2 0.0 3.2e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 AAAP01003877.1_46 - 1.7e-44 150.8 0.0 2.7e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AAAP01003877.1_46 - 1e-06 29.0 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AAAP01003877.1_46 - 2e-05 24.6 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AAAP01003877.1_46 - 0.025 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II Arf PF00025.21 AAAP01003877.1_46 - 0.03 13.8 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 AAAP01003877.1_46 - 0.21 11.1 0.0 5.4 6.5 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Herpes_gI PF01688.17 AAAP01003877.1_48 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Acylphosphatase PF00708.18 AAAP01003877.1_49 - 3.7e-22 78.5 0.0 4.1e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Glyco_hydro_1 PF00232.18 AAAP01003877.1_50 - 4e-146 487.0 0.0 5e-146 486.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 AAAP01003877.1_50 - 0.0054 16.2 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Self-incomp_S1 PF05938.11 AAAP01003877.1_50 - 0.11 13.0 0.0 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 MCPsignal PF00015.21 AAAP01003877.1_51 - 6.4e-33 114.0 27.7 6.4e-33 114.0 27.7 3.5 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003877.1_51 - 5.7e-09 36.2 4.0 1.1e-08 35.3 0.2 3.7 3 1 0 3 3 3 1 HAMP domain DUF1664 PF07889.12 AAAP01003877.1_51 - 0.003 17.6 21.4 0.037 14.0 1.4 4.6 2 2 2 4 4 4 3 Protein of unknown function (DUF1664) HTH_Tnp_Tc3_1 PF11427.8 AAAP01003877.1_51 - 0.047 13.6 1.1 0.14 12.0 0.2 2.3 3 0 0 3 3 3 0 Tc3 transposase DUF2525 PF10733.9 AAAP01003877.1_51 - 0.16 12.2 2.9 0.32 11.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) DUF948 PF06103.11 AAAP01003877.1_51 - 0.26 11.6 35.7 0.18 12.1 4.8 6.7 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) MtrB PF05440.12 AAAP01003877.1_51 - 0.59 10.6 3.0 2.5 8.6 0.1 3.5 4 1 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B SNARE PF05739.19 AAAP01003877.1_51 - 3.2 7.8 5.6 18 5.4 0.0 3.8 3 0 0 3 3 3 0 SNARE domain Syntaxin_2 PF14523.6 AAAP01003877.1_51 - 3.9 7.9 12.4 13 6.2 0.9 5.1 4 2 1 5 5 5 0 Syntaxin-like protein BLOC1_2 PF10046.9 AAAP01003877.1_51 - 5.4 7.4 14.0 20 5.5 1.3 4.7 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 AAAP01003877.1_51 - 7.3 4.4 16.7 0.33 8.9 3.2 2.7 1 1 0 2 2 2 0 Prominin Sec34 PF04136.15 AAAP01003877.1_51 - 8.7 6.2 11.4 7.4 6.4 0.1 4.3 3 2 1 4 4 4 0 Sec34-like family TMPIT PF07851.13 AAAP01003877.1_51 - 9.6 5.4 12.1 3.2 6.9 1.0 2.9 2 1 0 2 2 2 0 TMPIT-like protein MCPsignal PF00015.21 AAAP01003877.1_52 - 1.1e-35 123.0 60.7 1.9e-33 115.7 31.0 4.0 2 1 1 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain Hemerythrin PF01814.23 AAAP01003877.1_52 - 6e-10 39.8 0.1 6e-10 39.8 0.1 4.4 5 1 1 6 6 6 1 Hemerythrin HHE cation binding domain HAMP PF00672.25 AAAP01003877.1_52 - 2.7e-09 37.2 2.5 6.6e-09 36.0 0.1 3.1 3 0 0 3 3 2 1 HAMP domain DUF812 PF05667.11 AAAP01003877.1_52 - 0.0013 17.7 13.1 0.0013 17.7 13.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF812) DUF1664 PF07889.12 AAAP01003877.1_52 - 0.13 12.3 25.7 0.52 10.4 3.5 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) Dynactin_p22 PF07426.11 AAAP01003877.1_52 - 0.14 12.0 16.4 0.18 11.6 0.4 4.6 4 2 0 4 4 4 0 Dynactin subunit p22 BLOC1_2 PF10046.9 AAAP01003877.1_52 - 0.46 10.8 19.1 6.8 7.1 0.5 5.4 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ING PF12998.7 AAAP01003877.1_52 - 1.2 9.8 6.0 9.2 6.9 0.0 4.6 5 2 0 5 5 5 0 Inhibitor of growth proteins N-terminal histone-binding DUF2935 PF11155.8 AAAP01003877.1_52 - 3 8.2 11.3 57 4.1 0.4 5.3 3 2 1 4 4 4 0 Domain of unknown function (DUF2935) IFT46_B_C PF12317.8 AAAP01003877.1_52 - 7.8 6.2 6.3 2.4 7.8 0.4 2.9 1 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal XhlA PF10779.9 AAAP01003877.1_52 - 7.9 6.8 9.0 4 7.7 0.6 4.4 4 0 0 4 4 4 0 Haemolysin XhlA ThiC_Rad_SAM PF01964.18 AAAP01003877.1_53 - 6.2e-199 661.0 0.0 7.4e-199 660.8 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AAAP01003877.1_53 - 1.9e-30 104.5 0.1 5.2e-30 103.1 0.1 1.8 1 0 0 1 1 1 1 ThiC-associated domain SPOR PF05036.13 AAAP01003877.1_54 - 2.8e-10 40.4 0.1 2.8e-10 40.4 0.1 2.1 3 0 0 3 3 3 1 Sporulation related domain Sel1 PF08238.12 AAAP01003877.1_54 - 1.3e-09 38.4 10.3 0.00012 22.6 1.6 3.6 3 0 0 3 3 3 2 Sel1 repeat LysR_substrate PF03466.20 AAAP01003877.1_56 - 4.8e-48 163.3 1.6 4.8e-48 163.3 1.6 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003877.1_56 - 2.1e-21 75.7 0.7 3.4e-21 74.9 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AAAP01003877.1_56 - 0.0036 17.2 0.4 0.028 14.3 0.1 2.5 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AAAP01003877.1_56 - 0.032 14.3 0.1 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 AAAP01003877.1_56 - 0.032 13.8 0.1 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding VirD1 PF07328.11 AAAP01003877.1_56 - 0.058 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 LigB PF02900.18 AAAP01003877.1_57 - 7.6e-32 110.5 0.0 1.1e-31 109.9 0.0 1.3 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Hemerythrin PF01814.23 AAAP01003877.1_58 - 4e-14 53.3 3.0 4.4e-14 53.2 3.0 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4455 PF14643.6 AAAP01003877.1_58 - 0.0064 15.2 0.1 0.0076 15.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Glycos_transf_2 PF00535.26 AAAP01003877.1_59 - 4.3e-27 95.0 0.0 6.5e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003877.1_59 - 2.8e-05 24.1 0.0 4.4e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003877.1_59 - 0.011 15.3 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CopC PF04234.12 AAAP01003877.1_60 - 1.4e-14 54.9 0.0 1.8e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 CopC domain CopD PF05425.13 AAAP01003877.1_61 - 2.4e-15 56.8 9.4 2.4e-15 56.8 9.4 3.9 4 1 1 5 5 5 1 Copper resistance protein D NMT1_3 PF16868.5 AAAP01003877.1_62 - 4.9e-13 49.1 0.0 1.7e-12 47.4 0.0 1.8 1 1 1 2 2 2 1 NMT1-like family NMT1 PF09084.11 AAAP01003877.1_62 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like RibD_C PF01872.17 AAAP01003877.1_63 - 3.2e-18 66.3 0.0 7.4e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 AAAP01003877.1_63 - 1.9e-07 30.9 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase HD_5 PF13487.6 AAAP01003877.1_64 - 6.1e-24 84.1 0.0 1.2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 HD domain GAF PF01590.26 AAAP01003877.1_64 - 4.6e-12 46.7 0.0 8.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 GAF domain HD PF01966.22 AAAP01003877.1_64 - 8.1e-11 42.2 0.0 2.8e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 HD domain GAF_2 PF13185.6 AAAP01003877.1_64 - 4.2e-08 33.6 0.0 1.3e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AAAP01003877.1_64 - 2.3e-05 24.7 0.0 0.00057 20.2 0.0 2.5 3 0 0 3 3 3 1 GAF domain UbiD PF01977.16 AAAP01003877.1_65 - 6.1e-171 568.8 0.0 6.9e-171 568.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TNT PF14021.6 AAAP01003877.1_66 - 8.8e-28 96.7 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin MafB19-deam PF14437.6 AAAP01003877.1_67 - 6.7e-28 97.2 0.0 7.1e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AAAP01003877.1_67 - 1.3e-27 95.6 0.0 1.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 AAAP01003877.1_67 - 0.0017 18.4 1.2 0.0052 16.9 0.6 2.0 1 1 1 2 2 2 1 Bd3614-like deaminase Orbi_VP7 PF00897.17 AAAP01003877.1_67 - 0.064 12.2 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 SNAD4 PF18750.1 AAAP01003877.1_67 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 AAAP01003877.1_67 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 FCD PF07729.12 AAAP01003877.1_68 - 6.8e-25 87.9 7.0 1.8e-24 86.5 7.0 1.7 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 AAAP01003877.1_68 - 2.3e-18 65.6 0.4 5.8e-18 64.3 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AAAP01003877.1_68 - 9.9e-05 22.6 0.7 0.0011 19.3 0.0 2.5 3 0 0 3 3 3 1 Transcriptional regulator MarR_2 PF12802.7 AAAP01003877.1_68 - 0.0013 18.5 1.5 0.0079 16.1 0.1 2.5 2 0 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 AAAP01003877.1_68 - 0.0071 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 AAAP01003877.1_68 - 0.0072 16.3 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 AAAP01003877.1_68 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AAAP01003877.1_68 - 0.01 15.9 0.4 0.038 14.1 0.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AAAP01003877.1_68 - 0.015 15.2 0.0 0.053 13.4 0.0 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AAAP01003877.1_68 - 0.016 14.8 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AAAP01003877.1_68 - 0.022 14.7 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 MarR family PaaX PF07848.12 AAAP01003877.1_68 - 0.043 14.0 0.2 0.11 12.7 0.2 1.7 2 0 0 2 2 1 0 PaaX-like protein Queuosine_synth PF02547.15 AAAP01003877.1_68 - 0.1 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein HTH_IclR PF09339.10 AAAP01003877.1_68 - 0.1 12.4 1.0 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_27 PF13463.6 AAAP01003877.1_68 - 0.11 13.0 0.2 0.56 10.7 0.0 2.3 3 0 0 3 3 2 0 Winged helix DNA-binding domain HTH_5 PF01022.20 AAAP01003877.1_68 - 0.38 10.6 2.2 0.41 10.6 0.1 2.2 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family PYC_OADA PF02436.18 AAAP01003877.1_69 - 6.3e-73 244.7 0.0 1.2e-72 243.8 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_D2 PF02786.17 AAAP01003877.1_69 - 4.3e-71 238.8 0.1 7.5e-71 238.0 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAAP01003877.1_69 - 7.6e-40 135.9 0.1 1.1e-38 132.1 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAAP01003877.1_69 - 7.6e-33 112.8 0.0 2.1e-32 111.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 AAAP01003877.1_69 - 2e-31 109.5 0.0 3.5e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AAAP01003877.1_69 - 5.2e-14 51.8 2.9 1e-13 50.9 2.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AAAP01003877.1_69 - 2.2e-08 33.8 1.0 2.2e-06 27.4 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 AAAP01003877.1_69 - 7.4e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 AAAP01003877.1_69 - 0.016 15.9 1.5 0.11 13.2 1.1 2.4 1 1 0 1 1 1 0 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003877.1_69 - 0.019 14.2 0.8 0.45 9.7 0.1 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 AAAP01003877.1_69 - 0.021 14.9 0.0 0.059 13.4 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 AAAP01003877.1_69 - 0.031 14.0 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon PMT_2 PF13231.6 AAAP01003877.1_70 - 1.6e-06 28.4 3.3 1.6e-06 28.4 3.3 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PTPS_related PF10131.9 AAAP01003877.1_70 - 0.01 14.2 8.7 0.019 13.3 8.7 1.6 1 1 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein PseudoU_synth_1 PF01416.20 AAAP01003877.1_71 - 5.4e-44 149.1 0.0 1.2e-30 106.2 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase AAA_25 PF13481.6 AAAP01003877.1_71 - 0.051 13.1 0.2 0.15 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain Formyl_trans_N PF00551.19 AAAP01003877.1_72 - 1.6e-43 148.6 0.0 2.3e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AAAP01003877.1_72 - 2.2e-25 88.8 0.0 3.6e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Pep_deformylase PF01327.21 AAAP01003877.1_73 - 3.9e-53 179.3 0.0 4.4e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Methyltrans_RNA PF04452.14 AAAP01003877.1_74 - 1.1e-54 185.2 0.0 1.3e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MCPsignal PF00015.21 AAAP01003877.1_75 - 4.6e-29 101.4 41.4 9.1e-28 97.2 22.9 3.4 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003877.1_75 - 5.7e-09 36.2 0.5 5.7e-09 36.2 0.5 4.2 5 1 1 6 6 5 1 HAMP domain LPP PF04728.13 AAAP01003877.1_75 - 0.0025 18.2 1.4 0.0025 18.2 1.4 5.3 4 3 1 5 5 5 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 AAAP01003877.1_75 - 0.0035 17.4 8.1 0.33 11.0 0.4 4.0 2 2 3 5 5 5 3 Protein of unknown function (DUF1664) Laminin_I PF06008.14 AAAP01003877.1_75 - 0.02 14.6 21.8 0.046 13.4 6.3 3.3 1 1 2 3 3 3 0 Laminin Domain I MCC-bdg_PDZ PF10506.9 AAAP01003877.1_75 - 0.065 13.3 1.6 2.8 8.0 0.3 3.5 2 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA_13 PF13166.6 AAAP01003877.1_75 - 0.069 11.8 8.8 0.11 11.1 8.8 1.4 1 0 0 1 1 1 0 AAA domain Not3 PF04065.15 AAAP01003877.1_75 - 0.1 12.0 1.2 0.25 10.7 1.2 1.6 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF812 PF05667.11 AAAP01003877.1_75 - 0.25 10.2 8.7 0.046 12.6 4.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Transcrip_act PF04949.13 AAAP01003877.1_75 - 0.31 10.9 2.3 2.7 7.8 0.5 2.8 2 2 0 2 2 2 0 Transcriptional activator Laminin_II PF06009.12 AAAP01003877.1_75 - 0.41 10.7 18.5 0.16 12.0 2.6 4.2 2 2 2 4 4 4 0 Laminin Domain II Spc7 PF08317.11 AAAP01003877.1_75 - 0.47 9.3 13.2 6.4 5.6 7.4 3.5 3 1 1 4 4 4 0 Spc7 kinetochore protein IFT57 PF10498.9 AAAP01003877.1_75 - 0.51 9.3 6.5 12 4.8 0.0 2.8 4 0 0 4 4 4 0 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 AAAP01003877.1_75 - 0.54 10.5 8.1 2.6 8.2 5.0 3.2 4 1 0 4 4 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 AAAP01003877.1_75 - 0.77 9.8 7.0 0.13 12.3 0.7 2.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 AAAP01003877.1_75 - 0.79 10.2 3.1 25 5.4 0.2 3.8 2 1 3 5 5 5 0 Protein of unknown function DUF16 TMPIT PF07851.13 AAAP01003877.1_75 - 2.2 7.4 3.9 4.4 6.5 1.1 2.6 3 0 0 3 3 3 0 TMPIT-like protein DUF948 PF06103.11 AAAP01003877.1_75 - 5.2 7.4 22.9 1.8 8.9 1.6 5.6 4 2 1 5 5 4 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 AAAP01003877.1_75 - 5.4 6.3 6.4 13 5.0 1.1 3.4 2 2 0 3 3 3 0 CorA-like Mg2+ transporter protein Vps53_N PF04100.12 AAAP01003877.1_75 - 8.5 5.2 7.8 15 4.4 2.0 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal Atg14 PF10186.9 AAAP01003877.1_75 - 8.9 5.3 8.2 16 4.5 7.8 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Radical_SAM PF04055.21 AAAP01003877.1_77 - 2.5e-07 31.2 0.0 3.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AAAP01003877.1_77 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAAP01003877.1_77 - 0.033 14.5 0.1 0.053 13.8 0.1 1.4 1 1 0 1 1 1 0 4Fe-4S single cluster domain PTPS PF01242.19 AAAP01003877.1_78 - 5.3e-36 123.3 0.0 6.1e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase LysR_substrate PF03466.20 AAAP01003877.1_79 - 3.7e-41 140.8 4.9 5.1e-41 140.3 4.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003877.1_79 - 1.3e-21 76.3 1.0 3.8e-21 74.8 1.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PrpF PF04303.13 AAAP01003877.1_80 - 2.1e-108 362.6 0.3 2.4e-108 362.4 0.3 1.0 1 0 0 1 1 1 1 PrpF protein Pro_racemase PF05544.11 AAAP01003877.1_80 - 0.0016 17.5 0.9 0.036 13.1 0.0 2.1 2 0 0 2 2 2 2 Proline racemase Amidohydro_2 PF04909.14 AAAP01003877.1_81 - 2.1e-58 198.4 0.0 2.4e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase RraA-like PF03737.15 AAAP01003877.1_82 - 2.2e-39 135.0 4.4 3e-39 134.6 4.4 1.2 1 0 0 1 1 1 1 Aldolase/RraA DUF1932 PF09130.11 AAAP01003877.1_83 - 9e-16 57.6 1.3 1.9e-15 56.6 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 AAAP01003877.1_83 - 5.8e-10 39.6 0.2 5.1e-09 36.5 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AAAP01003877.1_83 - 8.6e-08 32.7 1.5 2.8e-07 31.0 0.2 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AAAP01003877.1_83 - 0.00052 19.4 0.1 0.00099 18.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAAP01003877.1_83 - 0.00064 20.0 0.2 0.0015 18.8 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 AAAP01003877.1_83 - 0.027 14.0 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_11 PF14833.6 AAAP01003877.1_83 - 0.03 14.5 0.5 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Amidohydro_2 PF04909.14 AAAP01003877.1_84 - 3.8e-52 177.9 5.1 4.4e-52 177.7 5.1 1.0 1 0 0 1 1 1 1 Amidohydrolase GFO_IDH_MocA PF01408.22 AAAP01003877.1_85 - 1.9e-22 80.3 1.7 2.9e-22 79.7 1.7 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 AAAP01003877.1_85 - 0.00089 19.7 0.3 0.0015 19.0 0.3 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAAP01003877.1_85 - 0.0035 17.9 0.6 0.0062 17.1 0.6 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 AAAP01003877.1_85 - 0.004 17.8 2.0 0.0064 17.1 2.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 AAAP01003877.1_85 - 0.014 15.7 0.8 0.028 14.7 0.9 1.5 1 1 0 1 1 1 0 TrkA-N domain OCD_Mu_crystall PF02423.15 AAAP01003877.1_85 - 0.039 12.9 0.5 0.055 12.4 0.5 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 AAAP01003877.1_85 - 0.063 13.5 0.7 0.11 12.8 0.7 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 AAAP01003877.1_85 - 0.37 11.5 1.6 4.4 8.1 1.6 2.4 1 1 0 1 1 1 0 CoA binding domain Aldo_ket_red PF00248.21 AAAP01003877.1_86 - 1.1e-54 185.7 0.0 1.2e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transgly PF00912.22 AAAP01003878.1_1 - 2e-61 206.5 0.0 2.7e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AAAP01003878.1_1 - 6.5e-09 35.4 0.0 9.3e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain RHH_5 PF07878.11 AAAP01003878.1_2 - 4.6e-06 26.4 0.3 6.5e-06 25.9 0.3 1.2 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 RHH_1 PF01402.21 AAAP01003878.1_2 - 8.7e-06 25.5 0.0 2e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family ParD PF09386.10 AAAP01003878.1_2 - 4.3e-05 23.8 0.0 0.00012 22.4 0.0 1.6 1 1 0 1 1 1 1 Antitoxin ParD RHH_3 PF12651.7 AAAP01003878.1_2 - 0.042 13.8 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF5063 PF16702.5 AAAP01003878.1_2 - 0.052 13.9 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) NMO PF03060.15 AAAP01003878.1_3 - 8.5e-08 31.9 0.0 3.4e-07 30.0 0.0 2.0 2 1 0 2 2 2 1 Nitronate monooxygenase GDPD PF03009.17 AAAP01003878.1_4 - 2e-40 139.2 0.0 2.3e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 AAAP01003878.1_4 - 0.0052 17.2 0.7 0.029 14.8 0.1 2.6 2 1 1 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family ThiG PF05690.14 AAAP01003878.1_4 - 0.086 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Glyco_transf_9 PF01075.17 AAAP01003878.1_5 - 1.5e-27 96.5 0.0 2.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glycos_transf_1 PF00534.20 AAAP01003878.1_5 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Copper-fist PF00649.18 AAAP01003878.1_5 - 0.19 11.3 0.7 0.36 10.4 0.7 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain PMT_2 PF13231.6 AAAP01003878.1_6 - 4.8e-37 127.6 18.3 4.8e-37 127.6 18.3 2.6 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 AAAP01003878.1_6 - 2.6e-09 37.0 14.8 2.6e-09 37.0 14.8 3.1 3 1 2 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Molybdopterin PF00384.22 AAAP01003878.1_8 - 6.1e-73 246.2 0.0 1.5e-72 244.9 0.0 1.6 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003878.1_8 - 4.1e-25 88.0 0.0 7.3e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003878.1_8 - 7.6e-16 57.9 0.1 1.6e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 AAAP01003878.1_8 - 4.4e-15 55.8 1.5 8e-15 54.9 0.9 1.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 AAAP01003878.1_9 - 2.9e-16 59.2 0.0 3.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AAAP01003878.1_9 - 1.3e-13 50.8 0.0 1.5e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_2 PF07992.14 AAAP01003878.1_10 - 7.9e-53 179.6 0.2 7.9e-53 179.6 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AAAP01003878.1_10 - 1.3e-28 99.1 6.7 3.1e-15 56.3 3.0 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 AAAP01003878.1_10 - 6e-27 94.1 0.2 1.1e-26 93.2 0.2 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rubredoxin_C PF18267.1 AAAP01003878.1_10 - 5.2e-20 71.1 0.0 1.8e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 AAAP01003878.1_10 - 1.4e-17 64.0 0.9 1.9e-14 53.9 0.1 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 AAAP01003878.1_10 - 1.6e-13 50.3 0.0 3.7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain DAO PF01266.24 AAAP01003878.1_10 - 3e-06 27.1 0.5 0.064 12.8 0.1 4.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AAAP01003878.1_10 - 3.7e-06 26.4 0.0 6.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AAAP01003878.1_10 - 1.9e-05 23.9 3.1 0.00013 21.1 0.1 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AAAP01003878.1_10 - 0.00032 19.9 0.6 0.066 12.2 0.0 3.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 AAAP01003878.1_10 - 0.0016 18.6 0.0 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AAAP01003878.1_10 - 0.002 17.4 2.0 0.36 10.1 0.1 3.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AAAP01003878.1_10 - 0.0028 16.8 0.8 0.033 13.3 0.2 2.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 AAAP01003878.1_10 - 0.0053 16.7 4.9 0.94 9.4 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 AAAP01003878.1_10 - 0.09 13.2 0.2 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 AAAP01003878.1_10 - 0.092 11.4 1.6 8.9 4.9 0.2 3.5 3 1 1 4 4 4 0 HI0933-like protein K_oxygenase PF13434.6 AAAP01003878.1_10 - 0.19 10.8 0.0 0.75 8.9 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NMT1_2 PF13379.6 AAAP01003878.1_11 - 2.8e-77 259.9 0.5 4.6e-77 259.1 0.5 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01003878.1_11 - 1.1e-05 25.6 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 NMT1/THI5 like ABC_tran PF00005.27 AAAP01003878.1_12 - 1.1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003878.1_12 - 2.2e-06 27.7 0.2 0.015 15.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AAAP01003878.1_12 - 5.4e-05 23.6 0.0 7.7e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003878.1_12 - 0.00026 21.0 0.1 0.00055 19.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AAAP01003878.1_12 - 0.001 18.7 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AAAP01003878.1_12 - 0.0011 19.2 0.0 0.0022 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003878.1_12 - 0.0071 16.5 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003878.1_12 - 0.008 16.6 0.0 0.045 14.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 AAAP01003878.1_12 - 0.014 14.2 1.4 0.22 10.3 0.0 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 AAAP01003878.1_12 - 0.06 12.9 0.6 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AAAP01003878.1_12 - 0.062 13.4 0.3 0.16 12.0 0.3 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 AAAP01003878.1_12 - 0.077 12.4 0.1 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAAP01003878.1_12 - 0.23 11.2 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain BPD_transp_1 PF00528.22 AAAP01003878.1_13 - 6.9e-24 84.6 18.8 1e-23 84.0 18.8 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component NMT1_2 PF13379.6 AAAP01003878.1_14 - 3.9e-102 341.3 1.8 5.1e-102 340.9 1.8 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AAAP01003878.1_14 - 6.4e-06 26.3 0.0 0.022 14.7 0.0 2.2 2 0 0 2 2 2 2 NMT1/THI5 like ANTAR PF03861.14 AAAP01003878.1_16 - 5.2e-19 67.8 4.5 5.2e-19 67.8 4.5 2.0 2 0 0 2 2 2 1 ANTAR domain Response_reg PF00072.24 AAAP01003878.1_16 - 6.4e-12 45.6 0.8 8.7e-12 45.2 0.2 1.6 2 0 0 2 2 2 1 Response regulator receiver domain OKR_DC_1_N PF03709.15 AAAP01003878.1_16 - 0.048 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain ATPgrasp_N PF18130.1 AAAP01003878.1_16 - 0.087 13.4 2.8 18 6.0 0.1 3.3 1 1 1 3 3 3 0 ATP-grasp N-terminal domain DUF2946 PF11162.8 AAAP01003878.1_18 - 0.004 17.8 14.7 0.0051 17.5 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Plug PF07715.15 AAAP01003878.1_19 - 5.1e-12 46.3 0.0 1.3e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AAAP01003878.1_19 - 0.0024 16.9 0.0 0.029 13.4 0.0 2.2 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family His_Phos_1 PF00300.22 AAAP01003878.1_20 - 3.3e-38 131.3 0.0 3.7e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CobS PF02654.15 AAAP01003878.1_22 - 1.4e-46 159.2 25.0 1.6e-46 159.1 25.0 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DBI_PRT PF02277.17 AAAP01003878.1_23 - 1.8e-109 365.9 12.6 2.1e-109 365.8 12.6 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase CW_binding_2 PF04122.12 AAAP01003878.1_23 - 0.87 10.3 4.0 25 5.6 0.1 3.2 3 1 0 3 3 3 0 Putative cell wall binding repeat 2 BMFP PF04380.13 AAAP01003878.1_24 - 5.5e-26 90.8 4.1 6.8e-26 90.6 4.1 1.1 1 0 0 1 1 1 1 Membrane fusogenic activity DUF3583 PF12126.8 AAAP01003878.1_24 - 0.00058 19.4 0.3 0.00066 19.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) YbjN PF10722.9 AAAP01003878.1_25 - 1.5e-34 118.8 0.2 1.8e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator P5CR_dimer PF14748.6 AAAP01003878.1_26 - 5.7e-32 110.1 5.5 1e-31 109.2 5.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AAAP01003878.1_26 - 5.1e-07 30.2 0.0 2.6e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Phasin_2 PF09361.10 AAAP01003878.1_27 - 1.7e-22 79.6 6.1 2.6e-22 78.9 6.1 1.3 1 0 0 1 1 1 1 Phasin protein DUF2935 PF11155.8 AAAP01003878.1_27 - 0.031 14.6 1.4 0.085 13.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) HisKA_3 PF07730.13 AAAP01003878.1_27 - 0.048 14.2 2.0 4.3 7.9 0.4 3.1 1 1 2 3 3 3 0 Histidine kinase Chlorosome_CsmC PF11098.8 AAAP01003878.1_27 - 0.072 13.1 0.0 0.098 12.6 0.0 1.3 1 1 0 1 1 1 0 Chlorosome envelope protein C TMP_2 PF06791.13 AAAP01003878.1_27 - 0.097 12.3 2.6 0.19 11.4 0.5 1.9 1 1 1 2 2 2 0 Prophage tail length tape measure protein MIF4G_like_2 PF09090.11 AAAP01003878.1_27 - 0.17 11.4 2.6 0.19 11.2 2.6 1.2 1 0 0 1 1 1 0 MIF4G like DUF883 PF05957.13 AAAP01003878.1_27 - 0.36 11.4 4.1 1 10.0 0.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HATPase_c PF02518.26 AAAP01003878.1_28 - 8.9e-29 100.3 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AAAP01003878.1_28 - 3.3e-17 63.1 0.0 5.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Cache domain HisKA PF00512.25 AAAP01003878.1_28 - 4.6e-17 61.8 0.0 4.6e-17 61.8 0.0 3.2 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01003878.1_28 - 0.034 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003878.1_28 - 0.037 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain LapA_dom PF06305.11 AAAP01003878.1_28 - 0.044 13.6 0.5 0.7 9.8 0.6 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Sensor PF13796.6 AAAP01003878.1_28 - 0.06 13.4 1.9 0.1 12.6 0.6 2.0 2 0 0 2 2 2 0 Putative sensor EVC2_like PF12297.8 AAAP01003878.1_28 - 0.087 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein TPR_14 PF13428.6 AAAP01003878.1_28 - 3.2 8.8 6.1 0.51 11.3 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CbiA PF01656.23 AAAP01003878.1_29 - 7.7e-12 45.4 0.0 9.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003878.1_29 - 3.2e-09 36.9 0.0 6.7e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 AAAP01003878.1_29 - 1e-08 34.8 0.6 1.8e-07 30.8 0.0 2.5 1 1 2 3 3 3 1 ATPase MipZ ParA PF10609.9 AAAP01003878.1_29 - 6.9e-05 22.4 0.2 0.00025 20.6 0.1 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 AAAP01003878.1_29 - 0.038 13.3 0.1 0.084 12.2 0.1 1.5 2 0 0 2 2 2 0 VirC1 protein AAA_16 PF13191.6 AAAP01003878.1_29 - 0.066 13.6 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ArsA_ATPase PF02374.15 AAAP01003878.1_29 - 0.093 11.9 0.4 0.14 11.3 0.4 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase SRP54 PF00448.22 AAAP01003878.1_29 - 0.17 11.5 0.3 0.42 10.2 0.3 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_26 PF13500.6 AAAP01003878.1_29 - 0.36 10.6 1.2 1.9 8.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain HATPase_c PF02518.26 AAAP01003878.1_30 - 8.6e-19 68.1 0.0 2.2e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003878.1_30 - 1e-08 35.4 3.8 1.2e-08 35.2 0.4 2.9 2 1 1 3 3 3 1 HAMP domain HisKA PF00512.25 AAAP01003878.1_30 - 2.9e-08 33.6 0.1 9.5e-08 32.0 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AAAP01003878.1_30 - 0.05 13.6 1.1 0.39 10.7 0.1 2.7 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AAAP01003878.1_30 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003878.1_31 - 4.1e-31 107.4 0.0 7.3e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003878.1_31 - 6.2e-20 71.1 0.1 1.6e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AAAP01003878.1_32 - 9.9e-15 54.2 0.1 1.8e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AAAP01003878.1_32 - 1.6e-06 27.9 0.1 2.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AAAP01003878.1_32 - 5.4e-06 26.8 0.2 1.4e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AAAP01003878.1_32 - 0.0064 16.0 0.1 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 AAAP01003878.1_32 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Aminotran_4 PF01063.19 AAAP01003878.1_33 - 1.1e-46 159.5 0.0 1.3e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MCPsignal PF00015.21 AAAP01003878.1_34 - 3.3e-33 114.9 44.3 3.5e-31 108.3 23.2 2.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003878.1_34 - 5.4e-08 33.1 0.1 5.4e-08 33.1 0.1 3.8 4 0 0 4 4 3 1 HAMP domain DUF948 PF06103.11 AAAP01003878.1_34 - 0.0004 20.6 31.7 0.0012 19.1 2.7 5.2 3 1 2 5 5 5 3 Bacterial protein of unknown function (DUF948) TACC_C PF05010.14 AAAP01003878.1_34 - 0.00049 20.0 9.4 0.12 12.1 0.3 2.4 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 AAAP01003878.1_34 - 0.003 17.6 29.2 0.016 15.2 5.2 4.4 2 2 2 4 4 4 2 Laminin Domain II AAA_13 PF13166.6 AAAP01003878.1_34 - 0.0032 16.2 17.3 0.024 13.3 17.3 2.0 1 1 0 1 1 1 1 AAA domain DUF1664 PF07889.12 AAAP01003878.1_34 - 0.009 16.0 17.2 0.55 10.3 0.7 4.2 2 2 2 4 4 4 3 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 AAAP01003878.1_34 - 0.049 13.9 14.3 2.8 8.3 0.2 4.6 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 AAAP01003878.1_34 - 0.077 10.9 10.3 0.12 10.2 10.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 AAAP01003878.1_34 - 0.097 13.0 7.5 6 7.1 0.1 3.3 2 1 1 3 3 3 0 Zinc finger-containing protein Laminin_I PF06008.14 AAAP01003878.1_34 - 0.11 12.1 26.1 0.5 10.0 8.4 3.7 1 1 2 3 3 3 0 Laminin Domain I DUF3450 PF11932.8 AAAP01003878.1_34 - 0.13 11.5 28.1 0.042 13.1 1.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) DUF2935 PF11155.8 AAAP01003878.1_34 - 0.17 12.2 2.3 4.5 7.6 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF3042 PF11240.8 AAAP01003878.1_34 - 0.27 11.3 0.1 0.27 11.3 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3042) SKA1 PF07160.12 AAAP01003878.1_34 - 0.49 10.2 9.2 2.5 7.9 0.6 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Nsp1_C PF05064.13 AAAP01003878.1_34 - 0.52 10.1 6.6 0.13 12.1 1.4 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region TMPIT PF07851.13 AAAP01003878.1_34 - 0.7 9.1 6.2 3.4 6.8 1.2 2.5 2 0 0 2 2 2 0 TMPIT-like protein PLU-1 PF08429.11 AAAP01003878.1_34 - 0.77 8.9 9.1 1.1 8.3 3.1 2.3 2 1 0 2 2 2 0 PLU-1-like protein PIN_8 PF18476.1 AAAP01003878.1_34 - 0.86 9.4 11.1 0.8 9.5 2.4 2.8 1 1 0 2 2 2 0 PIN like domain Sec34 PF04136.15 AAAP01003878.1_34 - 0.91 9.4 6.6 7.3 6.5 0.3 3.3 2 1 1 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 AAAP01003878.1_34 - 1.8 8.7 11.8 2.4 8.3 1.4 2.8 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 AAAP01003878.1_34 - 5.8 7.4 12.6 10 6.6 0.4 4.9 5 2 2 7 7 6 0 Flagella accessory protein C (FlaC) zf-DNL PF05180.12 AAAP01003878.1_35 - 0.00016 21.5 0.2 0.00018 21.4 0.2 1.2 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 AAAP01003878.1_35 - 0.0039 17.2 0.1 0.0053 16.8 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 AAAP01003878.1_35 - 0.021 15.0 0.3 0.031 14.4 0.3 1.3 1 0 0 1 1 1 0 Zinc ribbon domain zf-LITAF-like PF10601.9 AAAP01003878.1_35 - 0.069 13.4 0.9 0.11 12.8 1.0 1.4 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain DUF5040 PF16443.5 AAAP01003878.1_35 - 0.094 12.1 0.0 0.094 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) HD PF01966.22 AAAP01003878.1_36 - 8.8e-20 71.2 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 HD domain Response_reg PF00072.24 AAAP01003878.1_36 - 1.7e-18 66.8 0.0 2.8e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HD_5 PF13487.6 AAAP01003878.1_36 - 4.9e-17 62.0 0.1 1.2e-16 60.7 0.1 1.7 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AAAP01003878.1_36 - 4.2e-06 26.4 0.4 3e-05 23.6 0.4 2.1 1 1 0 1 1 1 1 HDOD domain sCache_2 PF17200.4 AAAP01003878.1_37 - 1.2e-44 151.8 0.1 1.2e-44 151.8 0.1 2.8 3 1 0 3 3 3 1 Single Cache domain 2 dCache_2 PF08269.11 AAAP01003878.1_37 - 8.7e-38 130.2 11.1 1.1e-36 126.5 0.0 3.3 3 1 0 3 3 3 1 Cache domain MCPsignal PF00015.21 AAAP01003878.1_37 - 6e-33 114.1 51.0 2.9e-32 111.9 27.2 3.3 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AAAP01003878.1_37 - 5.7e-12 45.8 0.6 5.7e-12 45.8 0.6 5.0 5 1 0 5 5 4 1 HAMP domain Cache_3-Cache_2 PF17201.4 AAAP01003878.1_37 - 6.4e-10 38.8 0.0 6.4e-10 38.8 0.0 3.7 3 1 0 3 3 3 1 Cache 3/Cache 2 fusion domain DUF3450 PF11932.8 AAAP01003878.1_37 - 0.00037 19.9 2.2 0.00037 19.9 2.2 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3450) DUF1664 PF07889.12 AAAP01003878.1_37 - 0.0011 19.0 15.5 0.1 12.7 3.2 3.6 2 2 0 2 2 2 2 Protein of unknown function (DUF1664) IFT57 PF10498.9 AAAP01003878.1_37 - 0.0015 17.6 9.0 0.059 12.3 0.4 2.2 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 DUF948 PF06103.11 AAAP01003878.1_37 - 0.0022 18.2 29.5 0.11 12.7 5.9 5.5 3 2 2 5 5 5 3 Bacterial protein of unknown function (DUF948) Rab5-bind PF09311.11 AAAP01003878.1_37 - 0.0087 15.5 4.1 0.0087 15.5 4.1 2.2 2 0 0 2 2 2 1 Rabaptin-like protein Sensor_TM1 PF13755.6 AAAP01003878.1_37 - 0.047 13.4 0.7 0.17 11.6 0.7 2.0 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF3584 PF12128.8 AAAP01003878.1_37 - 0.063 10.8 20.6 0.1 10.1 20.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.16 AAAP01003878.1_37 - 0.07 13.4 0.4 0.07 13.4 0.4 3.5 3 1 1 4 4 4 0 Flagellar FliJ protein COG5 PF10392.9 AAAP01003878.1_37 - 0.074 13.2 3.8 1.8 8.7 0.2 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 SKA1 PF07160.12 AAAP01003878.1_37 - 0.13 12.1 10.6 0.24 11.2 0.5 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Muted PF14942.6 AAAP01003878.1_37 - 0.18 12.1 9.9 1.2 9.4 3.7 3.0 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein zf-C4H2 PF10146.9 AAAP01003878.1_37 - 0.19 12.0 8.8 0.15 12.4 0.7 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein TMPIT PF07851.13 AAAP01003878.1_37 - 0.35 10.1 10.5 0.73 9.0 0.6 2.6 2 1 0 2 2 2 0 TMPIT-like protein Spc7 PF08317.11 AAAP01003878.1_37 - 0.44 9.4 14.3 0.54 9.1 1.2 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein PHM7_cyt PF14703.6 AAAP01003878.1_37 - 0.7 10.1 3.8 4.2 7.6 0.8 2.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter UPF0449 PF15136.6 AAAP01003878.1_37 - 0.74 10.3 6.8 0.74 10.3 2.2 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Fib_alpha PF08702.10 AAAP01003878.1_37 - 0.98 9.6 11.8 16 5.7 0.0 3.6 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family RmuC PF02646.16 AAAP01003878.1_37 - 2.4 7.2 20.0 0.49 9.5 2.7 4.0 3 2 1 4 4 4 0 RmuC family COG6 PF06419.11 AAAP01003878.1_37 - 2.5 6.2 10.9 3.3 5.8 3.2 2.2 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Seryl_tRNA_N PF02403.22 AAAP01003878.1_37 - 3 8.1 16.6 1.7 8.9 4.2 3.5 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain APH PF01636.23 AAAP01003878.1_37 - 3.1 7.6 9.0 0.54 10.1 2.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family GCN5L1 PF06320.13 AAAP01003878.1_37 - 3.4 7.8 21.9 0.12 12.5 6.1 3.4 3 1 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) STAT_alpha PF01017.20 AAAP01003878.1_37 - 4.2 7.2 7.9 2.3 8.1 0.9 3.0 2 1 1 3 3 3 0 STAT protein, all-alpha domain Syntaxin_2 PF14523.6 AAAP01003878.1_37 - 5 7.6 11.0 23 5.4 2.0 3.7 2 2 0 2 2 2 0 Syntaxin-like protein HAUS6_N PF14661.6 AAAP01003878.1_37 - 5.7 6.4 12.5 2.9 7.4 0.7 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Prominin PF05478.11 AAAP01003878.1_37 - 6.4 4.6 10.4 1.6 6.6 1.0 2.0 1 1 1 2 2 2 0 Prominin Aminotran_1_2 PF00155.21 AAAP01003878.1_38 - 8.5e-77 258.8 0.0 9.7e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AAAP01003878.1_38 - 9.5e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AAAP01003878.1_38 - 0.059 11.9 0.0 0.1 11.1 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Sel1 PF08238.12 AAAP01003878.1_39 - 9.3e-22 77.0 29.0 7.1e-05 23.4 0.1 7.1 7 0 0 7 7 7 6 Sel1 repeat TPR_14 PF13428.6 AAAP01003878.1_39 - 0.022 15.5 1.6 0.022 15.5 1.6 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat HisKA PF00512.25 AAAP01003878.1_39 - 0.054 13.5 0.2 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AAAP01003878.1_40 - 4.3e-06 26.9 0.1 8.1e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 Hpt domain DUF3670 PF12419.8 AAAP01003878.1_40 - 0.062 13.2 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 SNF2 Helicase protein Response_reg PF00072.24 AAAP01003878.1_41 - 2.4e-14 53.4 0.0 2.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GFO_IDH_MocA PF01408.22 AAAP01003878.1_41 - 0.01 16.6 0.1 0.014 16.2 0.1 1.3 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Synuclein PF01387.17 AAAP01003878.1_41 - 0.047 13.9 0.0 0.065 13.4 0.0 1.3 1 1 0 1 1 1 0 Synuclein DUF5536 PF17688.1 AAAP01003878.1_43 - 0.35 10.7 5.3 0.4 10.5 5.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5536) Pterin_4a PF01329.19 AAAP01003878.1_44 - 1.3e-32 111.8 0.3 1.5e-32 111.6 0.3 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sun2_CC2 PF18580.1 AAAP01003878.1_44 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 SUN2 coiled coil domain 2 Zincin_1 PF06262.11 AAAP01003878.1_45 - 7.2e-31 106.2 0.2 1.1e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 Zincin-like metallopeptidase Reprolysin_3 PF13582.6 AAAP01003878.1_45 - 0.064 13.8 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 AAAP01003878.1_45 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.24 AAAP01003878.1_45 - 0.16 11.8 1.1 0.32 10.8 1.1 1.2 1 1 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 AAAP01003878.1_45 - 0.23 11.6 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 AAAP01003878.1_45 - 0.25 10.9 0.7 0.37 10.4 0.7 1.1 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase SBP_bac_6 PF13343.6 AAAP01003878.1_46 - 3.6e-17 62.6 0.0 5.2e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AAAP01003878.1_46 - 3.1e-16 60.0 0.0 1.2e-15 58.1 0.0 1.7 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AAAP01003878.1_46 - 1.1e-05 25.6 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AAAP01003878.1_46 - 2.1e-05 24.4 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF805 PF05656.14 AAAP01003878.1_47 - 0.55 10.7 3.7 1 9.8 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Hydrolase_4 PF12146.8 AAAP01003878.1_48 - 5.8e-09 35.6 0.0 9.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AAAP01003878.1_48 - 3.2e-05 23.7 0.0 0.0001 22.0 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AAAP01003878.1_48 - 0.0001 23.0 5.1 0.0001 23.0 5.1 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family HATPase_c PF02518.26 AAAP01003878.1_49 - 9.7e-27 93.7 0.0 1.7e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AAAP01003878.1_49 - 1.2e-19 70.1 0.3 1.2e-18 66.9 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 AAAP01003878.1_49 - 4e-17 62.3 0.0 1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003878.1_49 - 3.2e-11 43.4 0.1 1.3e-10 41.5 0.1 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AAAP01003878.1_49 - 4.1e-11 43.1 0.0 8.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003878.1_49 - 1.6e-09 37.8 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AAAP01003878.1_49 - 4.4e-07 30.2 2.4 9e-07 29.2 0.7 2.6 2 0 0 2 2 2 1 HAMP domain PAS_8 PF13188.7 AAAP01003878.1_49 - 3.8e-05 23.6 0.0 0.00013 21.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain dCache_1 PF02743.18 AAAP01003878.1_49 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Cache domain HATPase_c_3 PF13589.6 AAAP01003878.1_49 - 0.042 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VWA_CoxE PF05762.14 AAAP01003878.1_50 - 1.2e-12 47.7 0.2 8.4e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein GFD1 PF17331.2 AAAP01003878.1_50 - 0.39 11.0 3.9 0.76 10.0 3.9 1.5 1 0 0 1 1 1 0 GFD1 mRNA transport factor Hemerythrin PF01814.23 AAAP01003878.1_51 - 3.3e-14 53.6 1.5 3.7e-14 53.5 1.5 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ANAPC2 PF08672.11 AAAP01003878.1_51 - 0.19 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 AAA_5 PF07728.14 AAAP01003878.1_52 - 3.5e-13 49.7 0.0 5.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AAAP01003878.1_52 - 1e-12 48.6 0.0 2e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAAP01003878.1_52 - 2.9e-06 27.6 0.0 1.2e-05 25.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AAAP01003878.1_52 - 4.9e-06 26.4 0.0 0.0076 16.0 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 AAAP01003878.1_52 - 7.7e-06 26.4 1.8 9.9e-05 22.8 0.9 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 AAAP01003878.1_52 - 0.00084 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 AAAP01003878.1_52 - 0.0014 18.6 0.2 0.0057 16.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF2075 PF09848.9 AAAP01003878.1_52 - 0.0019 17.5 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 AAAP01003878.1_52 - 0.0026 17.0 0.2 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 AAAP01003878.1_52 - 0.0031 18.0 0.0 0.008 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AAAP01003878.1_52 - 0.0051 17.2 0.0 0.054 13.9 0.1 2.6 2 1 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 AAAP01003878.1_52 - 0.0065 16.0 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 AAAP01003878.1_52 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AAAP01003878.1_52 - 0.0098 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AAAP01003878.1_52 - 0.017 15.0 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AAAP01003878.1_52 - 0.021 14.5 0.1 0.043 13.6 0.0 1.5 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 AAAP01003878.1_52 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AAAP01003878.1_52 - 0.025 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AAAP01003878.1_52 - 0.032 14.6 0.2 0.11 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AAAP01003878.1_52 - 0.047 13.0 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 AAAP01003878.1_52 - 0.053 12.9 0.2 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 AAAP01003878.1_52 - 0.068 13.3 0.1 0.28 11.3 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain gag-asp_proteas PF13975.6 AAAP01003878.1_52 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ResIII PF04851.15 AAAP01003878.1_52 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Asp_protease_2 PF13650.6 AAAP01003878.1_52 - 0.16 12.6 0.0 0.31 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Phasin_2 PF09361.10 AAAP01003878.1_53 - 3.1e-21 75.5 8.1 3.6e-21 75.3 8.1 1.1 1 0 0 1 1 1 1 Phasin protein PTH2 PF01981.16 AAAP01003878.1_53 - 0.088 13.1 0.5 0.11 12.8 0.5 1.1 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 CBS PF00571.28 AAAP01003878.1_54 - 2.3e-23 82.4 2.1 5.7e-13 49.1 0.6 2.1 2 0 0 2 2 2 2 CBS domain PGM_PMM_I PF02878.16 AAAP01003878.1_55 - 1.9e-31 108.6 0.0 3.2e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AAAP01003878.1_55 - 3.2e-21 75.9 0.0 6.6e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AAAP01003878.1_55 - 9.6e-21 74.1 0.0 2.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AAAP01003878.1_55 - 3.7e-13 49.5 0.1 9.1e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2218 PF09981.9 AAAP01003878.1_55 - 0.031 14.7 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) PGM_PMM_I PF02878.16 AAAP01003878.1_56 - 1.2e-35 122.2 0.1 2.1e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AAAP01003878.1_56 - 3.1e-29 101.5 0.0 5.5e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AAAP01003878.1_56 - 3.6e-13 50.0 0.1 4.2e-12 46.6 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AAAP01003878.1_56 - 6.3e-09 35.9 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain UDPG_MGDP_dh_C PF03720.15 AAAP01003878.1_57 - 3.7e-32 110.9 0.0 4.5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01003878.1_58 - 3.3e-69 232.2 0.2 4.1e-69 231.9 0.2 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAAP01003878.1_58 - 1.4e-19 70.1 0.0 4.8e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 AAAP01003878.1_58 - 5.1e-06 26.5 0.1 1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AAAP01003878.1_58 - 1.7e-05 25.3 0.1 0.0083 16.7 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 AAAP01003878.1_58 - 0.0019 18.1 1.2 0.0057 16.6 1.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 AAAP01003878.1_58 - 0.003 18.4 0.1 1.9 9.3 0.1 2.8 1 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_3 PF01494.19 AAAP01003878.1_58 - 0.0072 15.6 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AAAP01003878.1_58 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA OTCace PF00185.24 AAAP01003878.1_58 - 0.022 14.8 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ADH_zinc_N PF00107.26 AAAP01003878.1_58 - 0.026 14.5 0.5 0.55 10.2 0.1 2.6 2 1 1 3 3 3 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 AAAP01003878.1_58 - 0.027 14.6 0.2 0.09 12.9 0.2 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AAAP01003878.1_58 - 0.051 13.6 0.1 0.23 11.4 0.1 2.3 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AnmK PF03702.14 AAAP01003878.1_58 - 0.063 12.4 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase NTP_transferase PF00483.23 AAAP01003878.1_59 - 2e-26 93.1 0.0 2.5e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003878.1_59 - 1.3e-08 35.4 0.1 1.6e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DnaJ PF00226.31 AAAP01003878.1_60 - 8.4e-08 32.2 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CcmF_C PF16327.5 AAAP01003878.1_60 - 0.016 14.5 1.8 0.019 14.3 1.8 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Vma12 PF11712.8 AAAP01003878.1_60 - 0.033 14.2 0.9 0.16 12.0 0.4 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Wzy_C PF04932.15 AAAP01003878.1_60 - 0.047 13.3 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase DUF3318 PF11780.8 AAAP01003878.1_60 - 0.68 9.9 12.7 0.54 10.2 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) Phage_holin_3_6 PF07332.11 AAAP01003878.1_60 - 6.1 6.9 13.4 2.4 8.2 0.1 2.4 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III STAS_2 PF13466.6 AAAP01003878.1_61 - 2.2e-09 37.5 0.1 2.6e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AAAP01003878.1_61 - 1.2e-08 34.6 0.0 1.3e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 STAS domain AMP-binding PF00501.28 AAAP01003878.1_62 - 1.6e-42 145.6 0.0 2.3e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 AAAP01003878.1_62 - 1.8e-08 34.1 0.5 3.9e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 AAAP01003878.1_62 - 2.3e-06 28.5 2.1 4.7e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Carb_anhydrase PF00194.21 AAAP01003878.1_63 - 7.3e-43 146.9 0.0 1.4e-42 146.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TAT_signal PF10518.9 AAAP01003878.1_63 - 0.0037 17.0 1.5 0.0037 17.0 1.5 2.3 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence DEC-1_N PF04625.13 AAAP01003878.1_64 - 0.38 9.7 4.6 0.39 9.7 4.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OMP_b-brl PF13505.6 AAAP01003878.1_65 - 0.096 12.8 4.1 0.17 12.0 4.1 1.5 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain RsmJ PF04378.13 AAAP01003878.1_66 - 5e-86 287.9 0.0 5.8e-86 287.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 AAAP01003878.1_66 - 0.0039 16.8 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PAS_3 PF08447.12 AAAP01003878.1_67 - 4.8e-15 55.6 0.0 8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AAAP01003878.1_67 - 1.1e-12 48.1 0.0 1.7e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AAAP01003878.1_67 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AAAP01003878.1_67 - 5.9e-06 26.5 0.0 1.6e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AAAP01003878.1_67 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 1 1 0 1 1 1 1 PAS domain MCPsignal PF00015.21 AAAP01003878.1_68 - 2.6e-32 112.0 46.6 2.4e-30 105.6 28.7 3.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 AAAP01003878.1_68 - 5.2e-05 23.3 16.2 0.025 14.6 1.4 3.8 2 2 1 3 3 3 3 Protein of unknown function (DUF1664) DUF948 PF06103.11 AAAP01003878.1_68 - 0.0015 18.7 27.3 0.21 11.9 3.3 5.5 1 1 4 6 6 6 3 Bacterial protein of unknown function (DUF948) Myosin_tail_1 PF01576.19 AAAP01003878.1_68 - 0.0061 14.4 0.9 0.94 7.2 0.0 2.1 2 0 0 2 2 2 2 Myosin tail Serine_rich PF08824.10 AAAP01003878.1_68 - 0.011 15.8 7.3 0.14 12.2 2.5 2.9 2 1 1 3 3 3 0 Serine rich protein interaction domain Laminin_II PF06009.12 AAAP01003878.1_68 - 0.034 14.2 22.1 0.61 10.1 5.2 4.2 1 1 3 4 4 4 0 Laminin Domain II HAP1_N PF04849.13 AAAP01003878.1_68 - 0.044 13.0 2.9 5 6.2 1.6 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region CALCOCO1 PF07888.11 AAAP01003878.1_68 - 0.058 12.2 0.2 0.058 12.2 0.2 2.1 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMPIT PF07851.13 AAAP01003878.1_68 - 0.086 12.1 4.6 4.6 6.4 1.6 2.4 2 1 1 3 3 3 0 TMPIT-like protein Laminin_I PF06008.14 AAAP01003878.1_68 - 0.2 11.3 25.2 1.6 8.3 5.1 3.6 1 1 2 3 3 3 0 Laminin Domain I LXG PF04740.12 AAAP01003878.1_68 - 0.21 11.3 15.1 1.1 8.9 1.5 3.4 1 1 2 3 3 3 0 LXG domain of WXG superfamily Syntaxin-6_N PF09177.11 AAAP01003878.1_68 - 0.22 12.1 9.5 0.68 10.5 0.3 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal APG17 PF04108.12 AAAP01003878.1_68 - 0.27 10.3 9.5 1.6 7.7 3.1 2.3 2 0 0 2 2 2 0 Autophagy protein Apg17 IFT57 PF10498.9 AAAP01003878.1_68 - 0.46 9.4 6.5 6.6 5.6 1.0 2.6 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 AAAP01003878.1_68 - 0.57 9.0 10.2 0.95 8.3 4.2 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Prominin PF05478.11 AAAP01003878.1_68 - 0.62 7.9 7.4 2.5 5.9 0.5 2.4 1 1 2 3 3 3 0 Prominin Tropomyosin PF00261.20 AAAP01003878.1_68 - 0.68 9.3 15.1 2.9 7.2 8.7 3.0 1 1 2 3 3 3 0 Tropomyosin Fib_alpha PF08702.10 AAAP01003878.1_68 - 0.89 9.7 7.3 5.7 7.1 1.1 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 AAAP01003878.1_68 - 0.99 9.7 9.1 8 6.7 0.6 3.4 1 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 AAAP01003878.1_68 - 1 10.0 7.7 14 6.3 0.1 3.8 2 2 2 4 4 3 0 SlyX DUF724 PF05266.14 AAAP01003878.1_68 - 1 9.1 9.6 4.1 7.2 0.3 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF724) ALIX_LYPXL_bnd PF13949.6 AAAP01003878.1_68 - 1.1 8.4 8.8 2.2 7.5 0.2 2.7 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV COG2 PF06148.11 AAAP01003878.1_68 - 1.2 9.2 11.0 6.3 6.9 0.8 3.8 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 AAAP01003878.1_68 - 1.3 6.8 3.9 2 6.2 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec8_exocyst PF04048.14 AAAP01003878.1_68 - 1.4 8.8 7.0 3.8 7.4 2.3 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Dor1 PF04124.12 AAAP01003878.1_68 - 1.9 7.1 6.3 5.8 5.5 1.5 2.4 2 0 0 2 2 2 0 Dor1-like family DUF2935 PF11155.8 AAAP01003878.1_68 - 2.7 8.4 4.4 47 4.3 1.3 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) AAA_13 PF13166.6 AAAP01003878.1_68 - 2.8 6.5 13.9 5 5.6 12.1 1.8 1 1 1 2 2 2 0 AAA domain DUF3450 PF11932.8 AAAP01003878.1_68 - 3.1 7.0 19.6 1.5 8.1 3.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Filament PF00038.21 AAAP01003878.1_68 - 4.5 6.8 11.2 1.3 8.6 3.8 2.2 1 1 0 2 2 2 0 Intermediate filament protein HisKA_3 PF07730.13 AAAP01003878.1_68 - 5.5 7.6 18.6 2.1 8.9 0.1 4.9 4 1 1 5 5 4 0 Histidine kinase LOH1CR12 PF10158.9 AAAP01003878.1_68 - 8.7 6.4 12.8 20 5.2 0.4 3.6 2 2 0 3 3 3 0 Tumour suppressor protein Semialdhyde_dhC PF02774.18 AAAP01003878.1_70 - 6.8e-57 192.5 0.0 9.8e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AAAP01003878.1_70 - 3.9e-32 111.2 0.0 8e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 AAAP01003878.1_70 - 0.0026 17.4 1.5 0.0086 15.7 0.1 2.2 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ldh_1_N PF00056.23 AAAP01003878.1_70 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 AAAP01003878.1_70 - 0.037 14.7 0.1 0.13 13.0 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 AAAP01003878.1_70 - 0.069 13.3 0.6 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 AAAP01003878.1_70 - 0.074 13.6 0.2 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RAP-1 PF03085.15 AAAP01003878.1_70 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NmrA PF05368.13 AAAP01003878.1_70 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ABC_tran PF00005.27 AAAP01003878.1_71 - 1.1e-25 90.8 0.0 1.5e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003878.1_71 - 0.00012 22.0 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AAAP01003878.1_71 - 0.0025 17.3 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AAAP01003878.1_71 - 0.0055 17.1 0.1 0.01 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AAAP01003878.1_71 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 AAAP01003878.1_71 - 0.019 14.7 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 AAAP01003878.1_71 - 0.023 13.8 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 AAAP01003878.1_71 - 0.084 13.1 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 AAAP01003878.1_71 - 0.096 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 AAAP01003878.1_71 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 AAAP01003878.1_71 - 0.12 12.7 0.0 0.61 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AAAP01003878.1_71 - 0.13 12.0 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AAAP01003878.1_71 - 0.13 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 AAAP01003878.1_71 - 0.14 11.4 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin CbiA PF01656.23 AAAP01003878.1_71 - 0.15 12.1 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 AAAP01003878.1_71 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 AAAP01003878.1_71 - 0.18 11.8 0.2 0.3 11.1 0.2 1.3 1 0 0 1 1 1 0 Dynamin family NB-ARC PF00931.22 AAAP01003878.1_71 - 0.26 10.4 0.1 0.39 9.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain LysR_substrate PF03466.20 AAAP01003878.1_72 - 1.9e-47 161.4 8.8 3.1e-47 160.7 8.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AAAP01003878.1_72 - 8.9e-18 64.0 2.2 8.9e-18 64.0 2.2 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family Methyltransf_24 PF13578.6 AAAP01003878.1_73 - 9.8e-10 39.4 0.1 1.8e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 AAAP01003878.1_73 - 0.0012 18.1 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RecA PF00154.21 AAAP01003878.1_74 - 1.4e-144 480.4 3.0 1.7e-144 480.1 3.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AAAP01003878.1_74 - 3.7e-11 42.8 0.6 1.9e-10 40.5 0.6 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AAAP01003878.1_74 - 4.1e-08 32.8 1.5 1.1e-06 28.2 1.5 2.7 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 AAAP01003878.1_74 - 2.4e-06 27.7 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AAAP01003878.1_74 - 9.4e-05 22.9 0.1 0.00018 21.9 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AAAP01003878.1_74 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AAAP01003878.1_74 - 0.0015 18.2 0.5 0.012 15.2 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AAAP01003878.1_74 - 0.0016 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CobU PF02283.16 AAAP01003878.1_74 - 0.0047 16.5 0.0 0.0098 15.5 0.0 1.5 1 1 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.27 AAAP01003878.1_74 - 0.017 15.6 0.0 0.045 14.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter CLP1_P PF16575.5 AAAP01003878.1_74 - 0.035 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_35 PF14516.6 AAAP01003878.1_74 - 0.039 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 AAAP01003878.1_74 - 0.052 13.8 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AAAP01003878.1_74 - 0.072 13.0 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B DnaB_C PF03796.15 AAAP01003878.1_74 - 0.11 11.8 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 AAAP01003878.1_74 - 0.13 12.3 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PAS_4 PF08448.10 AAAP01003878.1_75 - 2e-30 105.3 4.1 2e-14 53.8 0.0 4.5 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 AAAP01003878.1_75 - 7.3e-21 74.3 0.0 1.6e-10 41.0 0.0 3.9 3 1 0 3 3 3 2 PAS fold HATPase_c PF02518.26 AAAP01003878.1_75 - 1.9e-19 70.2 0.0 4.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AAAP01003878.1_75 - 3.8e-17 62.5 0.0 7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 AAAP01003878.1_75 - 1.6e-15 57.2 0.0 1.9e-05 24.9 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.7 AAAP01003878.1_75 - 3.3e-15 55.7 1.0 2.3e-07 30.7 0.1 3.7 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 AAAP01003878.1_75 - 1e-08 35.1 0.0 3.3e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 AAAP01003878.1_75 - 0.0008 20.0 0.0 0.0084 16.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 AAAP01003878.1_75 - 0.078 13.1 0.1 2.7 8.2 0.0 3.1 3 1 0 3 3 3 0 PAS fold OB_aCoA_assoc PF01796.17 AAAP01003878.1_75 - 0.15 12.1 3.3 0.18 11.8 0.3 2.8 3 0 0 3 3 3 0 DUF35 OB-fold domain, acyl-CoA-associated Bac_export_2 PF01312.19 AAAP01003878.1_76 - 9.9e-126 419.4 7.4 1.1e-125 419.2 7.4 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family DUF3263 PF11662.8 AAAP01003878.1_76 - 0.019 14.8 0.6 0.04 13.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) DUF4808 PF16066.5 AAAP01003878.1_76 - 0.056 14.0 0.3 0.11 13.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Wzy_C PF04932.15 AAAP01003878.1_76 - 0.44 10.2 5.4 4.1 7.0 1.3 2.3 1 1 1 2 2 2 0 O-Antigen ligase PepSY_TM PF03929.16 AAAP01003878.1_76 - 0.56 9.8 3.1 0.83 9.3 1.9 1.5 1 1 0 1 1 1 0 PepSY-associated TM region DUF2085 PF09858.9 AAAP01003878.1_76 - 7 7.2 8.3 0.39 11.2 0.5 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) OppC_N PF12911.7 AAAP01003878.1_76 - 8.9 6.4 13.0 2.5 8.1 0.3 3.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Bac_export_1 PF01311.20 AAAP01003878.1_77 - 9.1e-58 195.5 31.2 1e-57 195.4 31.2 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_3 PF01313.19 AAAP01003878.1_78 - 4.1e-29 100.3 9.3 4.7e-29 100.1 9.3 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Bac_export_1 PF01311.20 AAAP01003878.1_78 - 0.0052 16.4 6.9 0.0059 16.2 6.9 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 MgtE PF01769.16 AAAP01003878.1_78 - 0.045 14.1 3.1 0.049 14.0 3.1 1.1 1 0 0 1 1 1 0 Divalent cation transporter Col_cuticle_N PF01484.17 AAAP01003878.1_78 - 0.14 12.3 2.3 1.8 8.7 0.2 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Bac_export_2 PF01312.19 AAAP01003878.1_78 - 2.7 7.1 6.9 7.4 5.7 6.9 1.6 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family FliE PF02049.18 AAAP01003878.1_79 - 1.2e-21 76.7 1.7 1.2e-21 76.7 1.7 1.3 1 1 0 1 1 1 1 Flagellar hook-basal body complex protein FliE DUF3972 PF13118.6 AAAP01003878.1_79 - 0.082 13.4 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Flg_bbr_C PF06429.13 AAAP01003878.1_80 - 9.1e-12 44.9 0.5 2.6e-11 43.5 0.5 1.8 1 1 1 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01003878.1_80 - 0.0051 16.7 0.1 0.0051 16.7 0.1 1.9 2 0 0 2 2 2 1 Flagella basal body rod protein PilM PF07419.12 AAAP01003878.1_80 - 0.035 14.3 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 PilM Flg_bb_rod PF00460.20 AAAP01003878.1_81 - 6.6e-06 25.9 0.2 1.8e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAAP01003878.1_81 - 0.034 14.3 0.4 0.056 13.6 0.4 1.6 1 1 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Bac_export_2 PF01312.19 AAAP01003878.1_82 - 9.6e-16 57.9 1.5 1.2e-15 57.6 1.5 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family LPD7 PF18821.1 AAAP01003878.1_82 - 0.022 14.9 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 FliO PF04347.13 AAAP01003878.1_84 - 1.1e-10 41.6 0.1 1.3e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO FliP PF00813.20 AAAP01003878.1_85 - 1.7e-80 269.4 13.1 2.1e-80 269.2 13.1 1.1 1 0 0 1 1 1 1 FliP family GTA_holin_3TM PF11351.8 AAAP01003878.1_85 - 0.031 14.8 1.7 3.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Flagellin_C PF00700.21 AAAP01003878.1_86 - 0.01 16.1 0.0 0.012 15.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Snapin_Pallidin PF14712.6 AAAP01003878.1_86 - 0.019 15.3 0.0 0.019 15.3 0.0 1.0 1 0 0 1 1 1 0 Snapin/Pallidin Iso_dh PF00180.20 AAAP01003878.1_87 - 1.7e-76 257.6 0.0 2e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 AAAP01003878.1_87 - 0.024 15.3 0.2 0.073 13.8 0.0 1.9 2 0 0 2 2 2 0 Phenylalanine zipper IDH PF03971.14 AAAP01003878.1_88 - 0 1324.0 0.8 0 1323.8 0.8 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DUF4115 PF13464.6 AAAP01003878.1_88 - 0.12 12.5 0.2 7.2 6.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) Big_6 PF17936.1 AAAP01003878.1_89 - 9e-14 51.5 0.0 1.9e-05 24.9 0.0 2.8 3 1 0 3 3 3 2 Bacterial Ig domain LysM PF01476.20 AAAP01003878.1_89 - 3.6e-09 36.5 0.0 6.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain bMG3 PF11974.8 AAAP01003878.1_89 - 6.1e-05 23.0 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial alpha-2-macroglobulin MG3 domain Big_3_5 PF16640.5 AAAP01003878.1_89 - 0.0038 17.4 0.1 2.3 8.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) BiPBP_C PF06832.12 AAAP01003878.1_89 - 0.016 15.3 0.2 0.099 12.7 0.1 2.4 1 1 1 2 2 2 0 Penicillin-Binding Protein C-terminus Family PS_Dcarbxylase PF02666.15 AAAP01003878.1_91 - 3.9e-32 111.4 0.0 2.1e-31 109.0 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF4131 PF13567.6 AAAP01003878.1_91 - 0.017 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CDP-OH_P_tran_2 PF08009.11 AAAP01003878.1_92 - 5.2e-14 51.9 9.2 5.2e-14 51.9 9.2 2.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase 2 CDP-OH_P_transf PF01066.21 AAAP01003878.1_92 - 1.9e-12 47.8 0.5 1.9e-12 47.8 0.5 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OmpA PF00691.20 AAAP01003878.1_93 - 4.7e-17 62.2 0.1 7.3e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 OmpA family OMP_b-brl PF13505.6 AAAP01003878.1_93 - 5.9e-16 59.1 14.0 6.8e-16 58.9 13.2 1.4 2 0 0 2 2 2 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 AAAP01003878.1_93 - 9.6e-08 32.2 2.5 3.4e-07 30.4 1.3 2.4 2 1 0 2 2 2 1 Opacity family porin protein OmpA_membrane PF01389.17 AAAP01003878.1_93 - 6.9e-07 29.2 5.2 9.8e-07 28.7 5.2 1.2 1 0 0 1 1 1 1 OmpA-like transmembrane domain Surface_Ag_2 PF01617.17 AAAP01003878.1_93 - 3.1e-06 26.8 1.3 0.00029 20.3 0.1 2.3 1 1 1 2 2 2 2 Surface antigen PagL PF09411.10 AAAP01003878.1_93 - 1.8e-05 24.9 2.5 0.00031 20.9 0.9 2.3 1 1 1 2 2 2 1 Lipid A 3-O-deacylase (PagL) OmpW PF03922.14 AAAP01003878.1_93 - 4.4e-05 23.4 0.6 8.7e-05 22.5 0.2 1.7 2 0 0 2 2 2 1 OmpW family C1ORF64 PF15547.6 AAAP01003878.1_93 - 0.0079 16.7 2.1 0.012 16.1 2.1 1.3 1 0 0 1 1 1 1 Steroid receptor-associated and regulated protein Pilus_CpaD PF09476.10 AAAP01003878.1_93 - 0.021 14.6 0.2 0.033 13.9 0.2 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) BBP2_2 PF10082.9 AAAP01003878.1_93 - 0.074 11.9 0.8 2.3 6.9 0.2 2.2 2 0 0 2 2 2 0 Putative beta-barrel porin 2 IalB PF06776.12 AAAP01003878.1_94 - 6.5e-05 23.0 0.1 0.0001 22.4 0.1 1.6 1 1 0 1 1 1 1 Invasion associated locus B (IalB) protein PEMT PF04191.13 AAAP01003878.1_95 - 0.00021 21.6 0.0 0.00048 20.5 0.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Wzy_C_2 PF11846.8 AAAP01003878.1_95 - 0.033 14.1 0.0 0.087 12.7 0.0 1.6 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ICMT PF04140.14 AAAP01003878.1_95 - 0.059 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TPR_2 PF07719.17 AAAP01003878.1_96 - 7.6e-06 25.6 7.6 0.00018 21.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003878.1_96 - 3.1e-05 23.6 0.1 0.0035 17.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003878.1_96 - 8.4e-05 23.1 11.1 0.0023 18.6 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003878.1_96 - 0.0015 18.8 6.2 0.022 15.0 0.0 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003878.1_96 - 0.0018 18.3 0.2 0.015 15.5 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003878.1_96 - 0.0039 17.7 2.5 1.9 9.1 1.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003878.1_96 - 0.031 14.1 4.8 2.8 7.9 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003878.1_96 - 0.054 13.2 0.2 0.52 10.0 0.0 2.5 3 0 0 3 3 3 0 TPR repeat TPR_4 PF07721.14 AAAP01003878.1_96 - 0.16 12.7 0.0 0.16 12.7 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TGT PF01702.18 AAAP01003878.1_97 - 2.6e-143 477.4 0.0 3.3e-143 477.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Queuosine_synth PF02547.15 AAAP01003878.1_98 - 4.2e-125 417.2 0.0 4.7e-125 417.0 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein Glyoxalase_6 PF18029.1 AAAP01003878.1_98 - 0.016 16.0 0.7 0.032 15.0 0.7 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Abhydrolase_1 PF00561.20 AAAP01003878.1_99 - 4.5e-27 95.3 0.0 1.4e-25 90.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01003878.1_99 - 4.8e-13 48.9 0.0 1.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 AAAP01003878.1_99 - 0.0029 17.7 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 AAAP01003878.1_99 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S28 PF05577.12 AAAP01003878.1_99 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Epimerase PF01370.21 AAAP01003878.1_100 - 8e-40 136.8 0.0 1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003878.1_100 - 6.2e-17 62.0 0.0 9.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01003878.1_100 - 1.7e-11 43.7 0.0 1.4e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01003878.1_100 - 7e-09 35.1 0.0 1.6e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01003878.1_100 - 9.4e-05 21.7 0.0 0.048 12.8 0.2 3.2 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003878.1_100 - 0.00011 21.5 0.2 0.09 11.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein KR PF08659.10 AAAP01003878.1_100 - 0.00028 20.8 1.0 0.0038 17.2 1.0 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 AAAP01003878.1_100 - 0.012 16.2 0.0 0.02 15.5 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AAAP01003878.1_100 - 0.2 11.9 0.2 1.5 9.1 0.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LGT PF01790.18 AAAP01003878.1_101 - 5.2e-74 248.5 8.2 5.9e-74 248.3 8.2 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Methyltransf_28 PF02636.17 AAAP01003878.1_102 - 7.2e-68 229.1 0.0 8.8e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Cu-oxidase_4 PF02578.15 AAAP01003878.1_103 - 1.1e-69 234.6 0.0 1.3e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Pribosyltran_N PF13793.6 AAAP01003878.1_105 - 1.6e-49 166.6 2.2 2.3e-48 163.0 0.1 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AAAP01003878.1_105 - 1.2e-26 93.9 3.7 1.4e-26 93.7 1.1 2.2 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AAAP01003878.1_105 - 8.3e-19 67.7 4.2 2e-18 66.4 2.6 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Sigma70_r2 PF04542.14 AAAP01003878.1_107 - 1.6e-19 69.4 0.4 2.9e-19 68.6 0.4 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AAAP01003878.1_107 - 3.7e-14 52.1 0.2 6.2e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AAAP01003878.1_107 - 2.3e-13 49.4 0.1 4.9e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AAAP01003878.1_107 - 5.4e-05 23.2 0.6 0.0027 17.6 0.6 2.1 1 1 0 1 1 1 1 ECF sigma factor DUF742 PF05331.11 AAAP01003878.1_107 - 0.00076 19.3 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_24 PF13412.6 AAAP01003878.1_107 - 0.021 14.4 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GerE PF00196.19 AAAP01003878.1_107 - 0.045 13.3 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_16 PF12645.7 AAAP01003878.1_107 - 0.087 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Cupin_7 PF12973.7 AAAP01003878.1_108 - 2.7e-10 40.0 0.0 3.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain zf-HC2 PF13490.6 AAAP01003878.1_108 - 0.00042 20.5 3.3 0.0012 19.1 3.3 1.8 1 0 0 1 1 1 1 Putative zinc-finger Cupin_2 PF07883.11 AAAP01003878.1_108 - 0.0057 16.3 0.3 0.017 14.8 0.3 1.8 1 1 0 1 1 1 1 Cupin domain adh_short PF00106.25 AAAP01003878.1_110 - 8.8e-44 149.3 0.0 1.2e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AAAP01003878.1_110 - 3.5e-29 102.0 0.2 4.3e-29 101.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AAAP01003878.1_110 - 1.4e-10 41.4 0.9 1.8e-10 41.0 0.9 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AAAP01003878.1_110 - 2.6e-07 30.7 1.4 3.7e-07 30.2 1.4 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AAAP01003878.1_110 - 8.6e-06 25.4 0.1 1.9e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glucokinase PF02685.16 AAAP01003878.1_110 - 0.021 13.9 3.7 0.032 13.2 3.7 1.2 1 0 0 1 1 1 0 Glucokinase NmrA PF05368.13 AAAP01003878.1_110 - 0.061 12.9 0.1 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 AAAP01003878.1_110 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 AAAP01003878.1_110 - 0.086 13.4 0.8 0.19 12.3 0.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SnoaL_2 PF12680.7 AAAP01003878.1_111 - 1.9e-11 44.5 0.3 2.6e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AAAP01003878.1_111 - 1.8e-06 27.7 0.1 3.8e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF2358 PF10184.9 AAAP01003878.1_111 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) DUF3833 PF12915.7 AAAP01003878.1_112 - 1.9e-67 225.9 0.3 2.2e-67 225.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3833) LPAM_1 PF08139.12 AAAP01003878.1_112 - 0.39 11.3 1.7 0.77 10.4 1.7 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MFS_2 PF13347.6 AAAP01003878.1_113 - 1.2e-67 228.3 16.6 1.4e-67 228.1 16.6 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 AAAP01003878.1_113 - 3.1e-09 36.2 52.0 2.7e-07 29.8 23.6 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily CMAS PF02353.20 AAAP01003878.1_114 - 7.8e-87 291.0 0.0 9.5e-87 290.8 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 AAAP01003878.1_114 - 3.1e-12 46.6 0.0 4.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003878.1_114 - 2.2e-11 44.3 0.0 4.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003878.1_114 - 1.2e-10 41.8 0.0 2.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003878.1_114 - 5e-07 30.4 0.0 8.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003878.1_114 - 0.00077 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAAP01003878.1_114 - 0.0025 17.6 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 AAAP01003878.1_114 - 0.025 14.7 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 AAAP01003878.1_114 - 0.028 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1365 PF07103.11 AAAP01003878.1_115 - 1.9e-63 214.3 0.0 2.2e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) NAD_binding_8 PF13450.6 AAAP01003878.1_116 - 2.2e-14 53.4 0.2 5.6e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AAAP01003878.1_116 - 3.2e-14 53.1 2.1 7.8e-12 45.2 0.0 2.3 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 AAAP01003878.1_116 - 6.9e-05 22.6 2.9 0.0013 18.4 0.4 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AAAP01003878.1_116 - 0.00078 19.5 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AAAP01003878.1_116 - 0.0015 17.8 0.0 0.022 14.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01003878.1_116 - 0.072 12.1 0.5 0.12 11.5 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 AAAP01003878.1_116 - 0.13 10.9 0.3 0.25 10.0 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 AAAP01003878.1_116 - 0.14 11.3 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_gyraseB PF00204.25 AAAP01003878.1_117 - 2.7e-54 183.3 0.0 4.2e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AAAP01003878.1_117 - 1.7e-29 101.7 0.0 4.5e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AAAP01003878.1_117 - 3.3e-19 69.4 0.0 6.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AAAP01003878.1_117 - 7e-18 64.8 0.0 2.7e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Toprim domain GyrB_insert PF18053.1 AAAP01003878.1_117 - 1.6e-06 28.2 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain Toprim_4 PF13662.6 AAAP01003878.1_117 - 0.047 14.2 0.0 0.64 10.5 0.0 2.7 2 0 0 2 2 2 0 Toprim domain SMC_N PF02463.19 AAAP01003878.1_118 - 3.2e-05 23.5 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AAAP01003878.1_118 - 0.028 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AhpC-TSA PF00578.21 AAAP01003879.1_1 - 5.1e-32 110.4 0.0 6.5e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AAAP01003879.1_1 - 1.8e-13 50.5 0.0 2.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AAAP01003879.1_1 - 6.4e-12 45.1 0.1 2.7e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AsnC_trans_reg PF01037.21 AAAP01003879.1_2 - 1.3e-20 73.2 0.0 2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AAAP01003879.1_2 - 7.3e-19 67.1 0.1 1.1e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AAAP01003879.1_2 - 3.6e-16 58.7 4.1 5.6e-16 58.1 4.1 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AAAP01003879.1_2 - 4.2e-06 26.7 0.1 9.4e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AAAP01003879.1_2 - 5.9e-05 22.9 0.1 9.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AAAP01003879.1_2 - 0.00032 20.4 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 AAAP01003879.1_2 - 0.00066 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_39 PF14090.6 AAAP01003879.1_2 - 0.0026 17.4 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AAAP01003879.1_2 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_47 PF16221.5 AAAP01003879.1_2 - 0.068 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 winged helix-turn-helix Rrf2 PF02082.20 AAAP01003879.1_2 - 0.094 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 AAAP01003879.1_2 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Cas_Cas1 PF01867.16 AAAP01003879.1_3 - 0.064 12.4 0.6 0.073 12.2 0.6 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas1 OST-HTH PF12872.7 AAAP01003879.1_5 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 OST-HTH/LOTUS domain Dfp1_Him1_M PF08630.10 AAAP01003879.1_6 - 0.14 12.4 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Dfp1/Him1, central region DUF760 PF05542.11 AAAP01003879.1_6 - 0.14 12.5 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF760) DUF4239 PF14023.6 AAAP01003879.1_7 - 1.7e-15 57.3 0.1 2e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Viral_DNA_bp PF00747.17 AAAP01003879.1_7 - 0.033 11.4 0.1 0.041 11.0 0.1 1.0 1 0 0 1 1 1 0 ssDNA binding protein Glucos_trans_II PF14264.6 AAAP01003879.1_7 - 0.033 13.5 0.3 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 Glucosyl transferase GtrII AveC_like PF17198.4 AAAP01003879.1_7 - 0.068 12.6 2.7 0.14 11.6 0.1 2.5 3 0 0 3 3 3 0 Spirocyclase AveC-like SirB PF04247.12 AAAP01003879.1_7 - 0.92 9.6 7.0 0.21 11.7 2.6 1.9 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Wzy_C PF04932.15 AAAP01003879.1_7 - 2 8.0 5.0 15 5.2 5.0 2.1 1 1 0 1 1 1 0 O-Antigen ligase HMGL-like PF00682.19 AAAP01003879.1_8 - 1.8e-59 201.5 0.1 2e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 HMGL-like Molydop_binding PF01568.21 AAAP01003879.1_8 - 0.13 12.2 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain PRA-PH PF01503.17 AAAP01003879.1_8 - 0.14 12.7 0.0 0.52 10.8 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase CPSase_L_D2 PF02786.17 AAAP01003879.1_9 - 3.3e-77 258.7 0.0 5e-77 258.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AAAP01003879.1_9 - 2.5e-45 153.5 0.2 6.5e-45 152.2 0.2 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AAAP01003879.1_9 - 1e-39 134.9 0.0 2.7e-39 133.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 AAAP01003879.1_9 - 1.1e-18 66.7 0.9 2.7e-18 65.6 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 AAAP01003879.1_9 - 7.5e-09 35.4 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AAAP01003879.1_9 - 3e-08 33.4 0.0 1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 AAAP01003879.1_9 - 5.3e-08 32.6 4.5 3.5e-06 26.7 0.1 3.0 2 1 1 3 3 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 AAAP01003879.1_9 - 6.4e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 AAAP01003879.1_9 - 0.00022 21.9 0.6 0.012 16.3 0.2 2.8 2 0 0 2 2 2 1 HlyD family secretion protein ATPgrasp_N PF18130.1 AAAP01003879.1_9 - 0.0061 17.1 1.2 2.5 8.7 0.1 2.9 3 0 0 3 3 3 1 ATP-grasp N-terminal domain RnfC_N PF13375.6 AAAP01003879.1_9 - 0.011 15.7 0.2 0.031 14.2 0.2 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.19 AAAP01003879.1_9 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAL_C2 PF18603.1 AAAP01003879.1_9 - 0.028 14.6 3.3 4.7 7.5 0.0 4.3 4 1 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 NQRA PF05896.11 AAAP01003879.1_9 - 0.048 13.1 0.3 0.089 12.2 0.3 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 AAAP01003879.1_9 - 0.055 12.7 0.3 0.68 9.1 0.1 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion FokI_N PF02981.15 AAAP01003879.1_9 - 0.081 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain PTS_EIIA_1 PF00358.20 AAAP01003879.1_9 - 0.12 12.1 0.1 2.1 8.1 0.0 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ECH_1 PF00378.20 AAAP01003879.1_10 - 5.6e-60 202.8 0.0 6.2e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003879.1_10 - 2.1e-32 113.0 0.5 1.4e-31 110.2 0.5 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3731 PF12531.8 AAAP01003879.1_10 - 0.0094 15.8 0.4 0.016 15.0 0.4 1.3 1 0 0 1 1 1 1 DNA-K related protein Abhydrolase_6 PF12697.7 AAAP01003879.1_10 - 0.36 11.4 2.7 0.55 10.8 2.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Carboxyl_trans PF01039.22 AAAP01003879.1_11 - 3.1e-150 501.1 0.1 3.7e-150 500.8 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AAAP01003879.1_11 - 0.0019 17.7 0.2 0.24 10.8 0.0 2.4 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 AAAP01003879.1_12 - 1.4e-40 138.9 0.4 2.4e-40 138.2 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 AAAP01003879.1_12 - 1.1e-38 132.4 0.1 2.8e-38 131.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 AAAP01003879.1_12 - 8.1e-27 93.3 0.1 1.6e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 AAAP01003879.1_12 - 2.8e-10 40.6 0.0 6.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mem_trans PF03547.18 AAAP01003879.1_13 - 4.5e-10 38.5 12.8 4.5e-10 38.5 12.8 2.0 2 0 0 2 2 2 2 Membrane transport protein SBF PF01758.16 AAAP01003879.1_13 - 0.002 17.9 4.0 0.002 17.9 4.0 2.3 2 0 0 2 2 2 1 Sodium Bile acid symporter family cNMP_binding PF00027.29 AAAP01003879.1_14 - 1.2e-20 73.3 0.0 1.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Patatin PF01734.22 AAAP01003879.1_15 - 7.7e-12 45.8 11.3 5.2e-11 43.1 11.3 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DNA_processg_A PF02481.15 AAAP01003879.1_16 - 8.4e-70 234.3 0.0 1.1e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AAAP01003879.1_16 - 7.3e-18 64.4 0.6 2.2e-17 62.9 0.6 1.9 1 0 0 1 1 1 1 DprA winged helix domain LDcluster4 PF18306.1 AAAP01003879.1_16 - 0.089 12.4 1.3 0.19 11.3 1.3 1.5 1 1 0 1 1 1 0 SLOG cluster4 family MarR_2 PF12802.7 AAAP01003879.1_16 - 0.14 12.1 2.7 0.51 10.3 0.0 3.2 4 0 0 4 4 4 0 MarR family Topoisom_bac PF01131.20 AAAP01003879.1_17 - 1.1e-121 406.7 0.0 1.5e-121 406.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim_C_rpt PF13368.6 AAAP01003879.1_17 - 2e-49 165.4 2.5 1.4e-18 66.6 0.0 4.5 4 0 0 4 4 4 3 Topoisomerase C-terminal repeat Toprim PF01751.22 AAAP01003879.1_17 - 8.3e-25 87.0 0.0 1.9e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 AAAP01003879.1_17 - 5.4e-14 51.7 1.4 1.5e-13 50.2 1.4 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Flagellin_N PF00669.20 AAAP01003879.1_18 - 8.4e-13 48.6 11.6 8.4e-13 48.6 11.6 2.9 3 1 0 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AAAP01003879.1_18 - 1.8e-06 28.2 2.1 1.8e-06 28.2 2.1 2.9 3 0 0 3 3 3 1 Bacterial flagellin C-terminal helical region DUF4156 PF13698.6 AAAP01003879.1_18 - 0.015 15.7 2.4 0.9 9.9 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4156) MAF_flag10 PF01973.18 AAAP01003879.1_19 - 1.3e-35 122.6 0.0 2.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPR_19 PF14559.6 AAAP01003879.1_20 - 7.2e-09 36.0 4.4 0.00016 22.1 1.3 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003879.1_20 - 2.3e-08 34.2 5.1 0.0012 19.5 1.2 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003879.1_20 - 3.6e-08 33.9 0.7 0.0042 17.7 2.7 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003879.1_20 - 0.0002 21.2 0.0 0.3 11.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 AAAP01003879.1_20 - 0.0003 20.9 3.5 0.37 11.0 4.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003879.1_20 - 0.014 15.6 0.1 0.048 13.9 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AAAP01003879.1_20 - 0.023 15.1 6.4 0.029 14.8 2.5 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 AAAP01003879.1_20 - 0.037 14.3 5.5 1.9 8.8 2.3 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003879.1_20 - 0.051 13.4 0.0 23 5.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CPT PF07931.12 AAAP01003879.1_20 - 0.12 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_4 PF07721.14 AAAP01003879.1_20 - 0.61 10.9 13.2 0.66 10.8 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 AAAP01003879.1_21 - 1.1e-07 30.7 0.0 1.1e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_19 PF14559.6 AAAP01003879.1_22 - 5.6e-05 23.6 1.2 0.00018 21.9 1.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003879.1_22 - 6.3e-05 23.5 2.9 6.3e-05 23.5 2.9 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 AAAP01003879.1_22 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) TPR_14 PF13428.6 AAAP01003879.1_22 - 0.011 16.5 1.6 0.011 16.5 1.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003879.1_22 - 0.038 13.7 0.2 0.081 12.6 0.2 1.6 1 0 0 1 1 1 0 TPR repeat FlaF PF07309.11 AAAP01003879.1_23 - 2.9e-18 65.9 0.0 3.5e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FlaF DUF2389 PF09493.10 AAAP01003879.1_23 - 0.16 12.7 0.0 0.23 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) CK2S PF15011.6 AAAP01003879.1_24 - 0.0099 15.8 2.4 0.0099 15.8 2.4 2.5 2 2 0 2 2 2 1 Casein Kinase 2 substrate Allexi_40kDa PF05549.11 AAAP01003879.1_24 - 0.036 13.6 6.7 0.42 10.1 2.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 AAAP01003879.1_24 - 0.058 13.8 7.9 8.1 6.9 0.1 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 AAAP01003879.1_24 - 0.27 11.5 10.8 2.1 8.6 0.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tweety PF04906.13 AAAP01003879.1_24 - 0.32 9.6 6.1 3.4 6.2 1.4 2.2 2 0 0 2 2 2 0 Tweety DUF1925 PF09094.11 AAAP01003879.1_24 - 0.48 10.8 2.5 0.55 10.6 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1925) Fib_alpha PF08702.10 AAAP01003879.1_24 - 0.51 10.5 14.1 0.17 12.1 0.7 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 AAAP01003879.1_24 - 0.57 10.7 5.2 2.2 8.9 0.6 2.6 2 1 0 2 2 2 0 YtxH-like protein Exonuc_VII_L PF02601.15 AAAP01003879.1_24 - 0.57 9.7 7.6 4.9 6.6 2.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF5344 PF17279.2 AAAP01003879.1_24 - 0.69 10.5 14.0 1 10.0 0.9 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5344) NPV_P10 PF05531.12 AAAP01003879.1_24 - 1.5 9.4 16.7 19 5.8 3.0 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 AAAP01003879.1_24 - 1.8 9.1 14.1 1.1 9.8 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 Vps5 PF09325.10 AAAP01003879.1_24 - 1.9 8.0 13.8 1.1 8.7 1.6 3.0 2 2 1 3 3 3 0 Vps5 C terminal like TMPIT PF07851.13 AAAP01003879.1_24 - 2 7.6 8.6 1.8 7.8 3.8 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 AAAP01003879.1_24 - 2.6 8.8 8.8 3 8.6 3.6 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Phage_Mu_Gam PF07352.12 AAAP01003879.1_24 - 2.9 7.8 13.1 1 9.3 5.9 2.6 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein UPF0242 PF06785.11 AAAP01003879.1_24 - 3.2 7.8 11.4 5.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 AAAP01003879.1_24 - 6.7 6.8 16.7 4.6 7.3 2.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaF PF07309.11 AAAP01003879.1_25 - 3.3e-19 69.0 0.0 4.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Flagellar protein FlaF TPR_16 PF13432.6 AAAP01003879.1_27 - 2e-21 76.3 30.8 5.4e-08 33.4 2.7 4.7 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003879.1_27 - 6.8e-21 73.2 0.8 3.6e-05 23.4 0.0 6.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003879.1_27 - 9.8e-20 69.0 9.4 0.00013 21.8 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003879.1_27 - 1.5e-18 66.8 19.3 2.5e-08 34.1 0.8 5.5 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003879.1_27 - 5.1e-17 60.6 0.1 0.0049 17.0 0.0 6.1 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003879.1_27 - 9.6e-15 54.9 9.7 1e-06 29.2 0.2 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003879.1_27 - 3.2e-14 52.4 25.8 0.00083 20.0 0.2 6.9 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003879.1_27 - 1.7e-12 46.7 40.0 0.025 15.2 2.7 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003879.1_27 - 5.1e-11 42.2 3.7 0.056 13.8 0.0 5.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003879.1_27 - 4e-10 39.2 19.4 0.0035 17.2 0.4 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003879.1_27 - 4e-10 39.7 9.7 0.002 18.6 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AAAP01003879.1_27 - 2.4e-08 34.1 0.0 0.0058 16.8 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AAAP01003879.1_27 - 1.7e-07 31.8 12.8 1.2e-06 29.1 4.1 2.7 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_7 PF13176.6 AAAP01003879.1_27 - 1.9e-07 30.6 14.0 0.1 12.6 0.1 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 AAAP01003879.1_27 - 4.1e-07 29.5 2.3 1.8e-06 27.4 0.7 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003879.1_27 - 9.5e-07 28.4 1.8 0.15 11.8 0.0 4.5 3 1 0 4 4 4 2 TPR repeat Wzy_C_2 PF11846.8 AAAP01003879.1_27 - 8.1e-06 25.9 0.8 0.27 11.2 0.0 3.3 2 1 2 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal TPR_21 PF09976.9 AAAP01003879.1_27 - 1.6e-05 24.7 4.4 0.03 14.0 0.2 3.4 1 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 AAAP01003879.1_27 - 2.4e-05 24.4 19.6 0.0032 17.6 2.2 4.3 1 1 3 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003879.1_27 - 0.00062 19.2 5.3 0.0035 16.8 4.1 3.0 1 1 0 1 1 1 1 MalT-like TPR region Coatomer_E PF04733.14 AAAP01003879.1_27 - 0.0034 16.8 0.1 0.013 14.9 0.0 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 AAAP01003879.1_27 - 0.02 15.3 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 AAAP01003879.1_27 - 0.036 14.1 0.1 8 6.6 0.0 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 AAAP01003879.1_27 - 0.077 13.1 0.6 9.6 6.3 0.1 3.4 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 AAAP01003879.1_27 - 0.34 11.3 4.5 4.1 7.8 0.5 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 AAAP01003879.1_28 - 7.7e-54 183.2 0.0 9.5e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAAP01003879.1_28 - 8.2e-05 21.7 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01003879.1_28 - 0.00011 20.9 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AAAP01003879.1_28 - 0.056 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family P-II PF00543.22 AAAP01003879.1_29 - 3e-42 143.4 1.0 3.7e-42 143.1 1.0 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AAAP01003879.1_29 - 0.014 15.5 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) VbhA PF18495.1 AAAP01003879.1_29 - 0.057 13.3 0.5 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Antitoxin VbhA Gln-synt_C PF00120.24 AAAP01003879.1_30 - 6.3e-137 456.2 0.0 7.5e-137 455.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AAAP01003879.1_30 - 2.5e-29 100.8 0.3 4.7e-29 99.9 0.3 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Flagellin_N PF00669.20 AAAP01003879.1_31 - 1.4e-06 28.5 8.6 1.4e-06 28.5 8.6 2.6 2 0 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AAAP01003879.1_31 - 5.3e-06 26.7 2.9 1.1e-05 25.7 0.6 2.8 2 0 0 2 2 2 1 Bacterial flagellin C-terminal helical region Flg_bbr_C PF06429.13 AAAP01003879.1_32 - 5.6e-14 52.0 6.0 6.3e-14 51.9 1.3 3.5 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01003879.1_32 - 2.4e-06 27.3 0.7 1.4e-05 24.9 0.7 2.5 1 0 0 1 1 1 1 Flagella basal body rod protein Flagellin_IN PF07196.13 AAAP01003879.1_32 - 0.00011 22.3 21.5 0.0047 17.1 5.0 4.6 4 0 0 4 4 4 2 Flagellin hook IN motif KinB_sensor PF16767.5 AAAP01003879.1_32 - 0.11 12.9 6.1 0.43 11.0 0.7 2.7 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Syntaxin_2 PF14523.6 AAAP01003879.1_32 - 0.57 10.6 3.7 1.3 9.4 1.5 2.7 2 0 0 2 2 2 0 Syntaxin-like protein CSN5_C PF18323.1 AAAP01003879.1_32 - 1.1 10.2 7.8 2.1 9.3 0.1 4.2 4 1 0 4 4 4 0 Cop9 signalosome subunit 5 C-terminal domain FlgN PF05130.12 AAAP01003879.1_33 - 0.00012 22.6 0.7 0.0039 17.7 0.7 2.1 1 1 0 1 1 1 1 FlgN protein Rod-binding PF10135.9 AAAP01003879.1_34 - 1.6e-10 41.4 0.2 1.6e-10 41.4 0.2 2.3 1 1 1 2 2 2 1 Rod binding protein DUF305 PF03713.13 AAAP01003879.1_34 - 0.0013 18.9 1.9 0.0019 18.4 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) TGase_elicitor PF16683.5 AAAP01003879.1_34 - 0.097 11.4 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Transglutaminase elicitor FlgI PF02119.16 AAAP01003879.1_35 - 2.9e-139 463.8 6.9 3.3e-139 463.6 6.9 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein FliX PF10768.9 AAAP01003879.1_36 - 2.8e-45 154.2 3.7 3.1e-45 154.0 3.7 1.0 1 0 0 1 1 1 1 Class II flagellar assembly regulator RsmF_methylt_CI PF17126.5 AAAP01003879.1_36 - 0.013 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 RsmF rRNA methyltransferase first C-terminal domain zf-dskA_traR PF01258.17 AAAP01003879.1_37 - 2.8e-12 46.3 0.4 4.2e-12 45.8 0.4 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger MCPsignal PF00015.21 AAAP01003879.1_38 - 5.1e-15 55.7 1.1 8.1e-15 55.1 1.1 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AAAP01003879.1_38 - 1.3e-11 44.8 0.2 4e-11 43.2 0.2 1.8 1 1 0 1 1 1 1 Cache domain EamA PF00892.20 AAAP01003879.1_39 - 9e-21 74.5 15.4 1e-20 74.3 15.4 1.0 1 0 0 1 1 1 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 AAAP01003879.1_39 - 0.0048 16.0 0.7 0.0048 16.0 0.7 1.7 2 0 0 2 2 2 1 Magnesium transporter NIPA DUF202 PF02656.15 AAAP01003879.1_39 - 0.042 14.3 18.8 0.043 14.3 3.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF3021 PF11457.8 AAAP01003879.1_39 - 0.11 12.8 6.3 0.086 13.2 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) MipZ PF09140.11 AAAP01003879.1_40 - 3e-118 393.8 0.0 3.6e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 ATPase MipZ CbiA PF01656.23 AAAP01003879.1_40 - 4.5e-10 39.7 0.0 1.2e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AAAP01003879.1_40 - 2.4e-09 37.4 0.0 2.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ParA PF10609.9 AAAP01003879.1_40 - 4.7e-08 32.8 0.2 9.6e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase LpxK PF02606.14 AAAP01003879.1_40 - 0.0043 16.2 0.4 0.0068 15.5 0.4 1.2 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase CLP1_P PF16575.5 AAAP01003879.1_40 - 0.0046 16.8 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 AAAP01003879.1_40 - 0.029 13.4 0.0 0.073 12.0 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 AAAP01003879.1_40 - 0.043 13.2 0.7 0.076 12.4 0.7 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_26 PF13500.6 AAAP01003879.1_40 - 0.053 13.3 0.0 0.23 11.3 0.0 2.1 1 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AAAP01003879.1_40 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase GPHH PF16905.5 AAAP01003879.1_40 - 0.12 12.1 0.0 19 5.1 0.0 2.4 1 1 1 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Molybdopterin PF00384.22 AAAP01003879.1_41 - 2.4e-57 194.9 0.0 2e-56 191.8 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003879.1_41 - 9e-16 57.9 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003879.1_41 - 0.0017 18.3 0.4 0.0034 17.3 0.4 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain SCO1-SenC PF02630.14 AAAP01003879.1_41 - 0.17 11.8 0.1 14 5.6 0.0 2.3 2 0 0 2 2 2 0 SCO1/SenC DAO PF01266.24 AAAP01003879.1_42 - 9.4e-59 199.8 8.0 1e-58 199.6 8.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003879.1_42 - 0.00019 21.6 1.6 0.00053 20.2 1.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01003879.1_42 - 0.00084 18.7 2.4 0.0016 17.8 1.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AAAP01003879.1_42 - 0.0015 17.3 4.3 0.14 10.8 3.5 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 AAAP01003879.1_42 - 0.003 16.8 2.1 0.0065 15.7 2.1 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 AAAP01003879.1_42 - 0.014 14.7 0.9 0.022 14.1 0.9 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 AAAP01003879.1_42 - 0.019 14.3 0.8 0.026 13.8 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AAAP01003879.1_42 - 0.095 13.3 2.8 0.18 12.4 2.8 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AAAP01003879.1_42 - 0.098 11.7 9.3 0.14 11.2 9.3 1.4 1 1 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01003879.1_42 - 0.47 10.0 1.4 0.75 9.3 1.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 AAAP01003879.1_42 - 0.54 9.4 4.8 0.95 8.6 4.8 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 AAAP01003879.1_42 - 0.73 9.0 4.3 1.3 8.2 4.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AAAP01003879.1_42 - 2.9 7.1 5.6 0.64 9.3 2.7 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_114 PF03537.13 AAAP01003879.1_43 - 0.0021 17.4 0.1 0.0046 16.3 0.0 1.5 2 0 0 2 2 2 1 Glycoside-hydrolase family GH114 AMP-binding PF00501.28 AAAP01003879.1_44 - 5.8e-46 156.9 0.0 8.3e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AAAP01003879.1_44 - 0.016 16.2 0.6 0.016 16.2 0.6 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 AAAP01003879.1_47 - 2.2e-25 89.6 0.0 3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AAAP01003879.1_47 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Allinase FlaF PF07309.11 AAAP01003879.1_48 - 2.5e-12 46.8 0.1 2.9e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 Flagellar protein FlaF GIT_CC PF16559.5 AAAP01003879.1_48 - 0.031 14.1 0.0 0.084 12.8 0.0 1.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Glyco_transf_41 PF13844.6 AAAP01003879.1_49 - 3.8e-94 315.8 0.0 1.5e-51 175.3 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_16 PF13432.6 AAAP01003879.1_49 - 5.4e-14 52.6 1.9 1.8e-06 28.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003879.1_49 - 2.8e-12 45.8 0.0 0.00056 19.8 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003879.1_49 - 2.3e-10 40.0 0.0 0.0028 17.3 0.0 3.6 1 1 2 3 3 3 3 TPR repeat TPR_19 PF14559.6 AAAP01003879.1_49 - 6.6e-08 32.9 1.8 0.00027 21.4 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003879.1_49 - 2.9e-07 30.0 0.0 4.5e-05 23.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003879.1_49 - 1.5e-06 28.5 14.6 0.05 14.4 0.0 6.0 3 2 4 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003879.1_49 - 5e-06 26.3 0.0 0.01 16.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003879.1_49 - 1.8e-05 24.8 0.0 2.8 8.5 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003879.1_49 - 0.00025 20.8 0.8 0.047 13.6 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AAAP01003879.1_49 - 0.0016 18.7 0.2 0.0016 18.7 0.2 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003879.1_49 - 0.0055 16.6 0.1 0.3 11.2 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003879.1_49 - 0.016 15.8 8.8 0.047 14.3 0.1 5.2 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 AAAP01003879.1_49 - 0.086 13.3 2.5 0.13 12.7 0.2 2.4 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 AAAP01003879.1_49 - 0.11 12.7 10.1 0.46 10.7 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003879.1_49 - 0.25 12.1 1.7 21 6.0 0.0 4.1 3 1 0 3 3 2 0 Tetratricopeptide repeat Acetyltransf_6 PF13480.7 AAAP01003879.1_50 - 7.4e-07 29.4 1.0 7.4e-07 29.4 1.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 AAAP01003879.1_50 - 0.044 12.7 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 FemAB family DegT_DnrJ_EryC1 PF01041.17 AAAP01003879.1_51 - 2.1e-91 307.0 0.0 7.1e-91 305.2 0.0 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAAP01003879.1_51 - 6.5e-05 22.0 0.2 9.5e-05 21.5 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AAAP01003879.1_51 - 0.0032 16.1 0.2 0.005 15.4 0.2 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 AAAP01003879.1_51 - 0.059 12.1 0.3 0.13 11.0 0.3 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain GFO_IDH_MocA PF01408.22 AAAP01003879.1_52 - 9.1e-13 49.1 0.0 1.7e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CTP_transf_3 PF02348.19 AAAP01003879.1_53 - 1.2e-28 100.5 0.0 1.5e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01003879.1_53 - 9.4e-11 42.3 0.5 1.5e-10 41.7 0.3 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 AAAP01003879.1_53 - 0.05 13.4 0.2 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) PseudoU_synth_2 PF00849.22 AAAP01003879.1_55 - 3e-15 56.6 0.0 4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase SgrR_N PF12793.7 AAAP01003879.1_55 - 0.13 12.5 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term UvrB_inter PF17757.1 AAAP01003879.1_56 - 1.6e-33 114.7 0.0 9.9e-33 112.2 0.0 2.1 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 AAAP01003879.1_56 - 3.7e-20 71.5 0.2 9.9e-20 70.1 0.2 1.8 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AAAP01003879.1_56 - 9.6e-18 64.5 0.1 2.3e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAAP01003879.1_56 - 2.5e-10 40.6 0.0 1.6e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 AAAP01003879.1_56 - 7.1e-08 32.0 7.1 2.6e-07 30.1 7.1 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 AAAP01003879.1_56 - 1.3e-05 25.0 0.0 4.4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AAAP01003879.1_56 - 3.1e-05 23.8 0.0 0.0019 18.0 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 AAAP01003879.1_56 - 0.0024 18.2 0.0 0.87 9.9 0.0 3.0 3 1 0 3 3 3 1 AAA domain Microtub_bd PF16796.5 AAAP01003879.1_56 - 0.024 14.6 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 Microtubule binding UB2H PF14814.6 AAAP01003879.1_56 - 0.031 14.3 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain eIF3_p135 PF12807.7 AAAP01003879.1_56 - 0.064 13.3 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Kinesin PF00225.23 AAAP01003879.1_56 - 0.16 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Phe_tRNA-synt_N PF02912.18 AAAP01003879.1_56 - 1.2 9.1 3.6 12 5.9 0.2 2.6 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pkinase PF00069.25 AAAP01003879.1_57 - 1.1e-24 87.2 0.0 2.2e-24 86.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 AAAP01003879.1_57 - 2.9e-17 62.8 0.0 2.7e-16 59.6 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 AAAP01003879.1_57 - 0.0014 18.6 0.5 0.34 10.8 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 AAAP01003879.1_57 - 0.017 14.4 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 AAAP01003879.1_57 - 0.044 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short_C2 PF13561.6 AAAP01003879.1_58 - 7e-36 123.9 0.6 8.1e-36 123.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003879.1_58 - 2.1e-35 122.0 0.1 2.6e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003879.1_58 - 1e-07 32.1 0.6 1.5e-07 31.5 0.6 1.2 1 0 0 1 1 1 1 KR domain UvrC_HhH_N PF08459.11 AAAP01003879.1_59 - 2.8e-52 176.7 0.0 5.9e-52 175.7 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal HHH_2 PF12826.7 AAAP01003879.1_59 - 9.2e-08 32.1 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif UVR PF02151.19 AAAP01003879.1_59 - 4.8e-07 29.3 2.3 9.8e-07 28.3 2.3 1.5 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_5 PF14520.6 AAAP01003879.1_59 - 4.8e-07 30.3 0.0 1.6e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain GIY-YIG PF01541.24 AAAP01003879.1_59 - 1.7e-06 28.2 0.0 3.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH PF00633.23 AAAP01003879.1_59 - 5.7e-06 25.9 0.1 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 AAAP01003879.1_59 - 0.07 13.4 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Translat_reg PF01818.17 AAAP01003879.1_59 - 0.13 12.3 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage translational regulator CDP-OH_P_transf PF01066.21 AAAP01003879.1_60 - 5.7e-18 65.4 0.7 5.7e-18 65.4 0.7 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MobB PF03205.14 AAAP01003879.1_61 - 1.1e-31 109.5 0.0 1.3e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MoeA_N PF03453.17 AAAP01003879.1_62 - 5.7e-42 143.1 1.4 1.1e-41 142.2 1.4 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AAAP01003879.1_62 - 1.1e-23 83.5 0.0 1.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AAAP01003879.1_62 - 5.8e-19 68.0 0.0 1.5e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ThiS PF02597.20 AAAP01003879.1_63 - 1e-17 64.5 0.0 1.1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family MoaE PF02391.17 AAAP01003879.1_64 - 8.9e-34 116.2 0.0 1.1e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein MCPsignal PF00015.21 AAAP01003879.1_66 - 2.5e-34 118.5 29.2 2.5e-34 118.5 29.2 3.5 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AAAP01003879.1_66 - 7.8e-16 58.1 1.0 7.8e-16 58.1 1.0 4.2 2 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction Hemerythrin PF01814.23 AAAP01003879.1_66 - 5.6e-11 43.2 2.9 5.6e-11 43.2 2.9 4.2 4 2 0 4 4 4 1 Hemerythrin HHE cation binding domain HAMP PF00672.25 AAAP01003879.1_66 - 4.5e-10 39.8 2.9 2e-09 37.6 0.0 3.6 3 0 0 3 3 3 1 HAMP domain TACC_C PF05010.14 AAAP01003879.1_66 - 0.0094 15.8 1.6 0.0094 15.8 1.6 3.3 3 1 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 AAAP01003879.1_66 - 0.01 15.8 28.4 0.038 14.0 3.6 5.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 AAAP01003879.1_66 - 0.1 11.7 21.0 0.3 10.1 9.2 2.5 1 1 1 2 2 2 0 Actin interacting protein 3 DUF948 PF06103.11 AAAP01003879.1_66 - 0.51 10.6 32.2 1.5 9.1 5.0 6.1 3 2 4 7 7 7 0 Bacterial protein of unknown function (DUF948) RapH_N PF18801.1 AAAP01003879.1_66 - 2.5 8.2 4.0 37 4.5 0.1 4.1 4 0 0 4 4 4 0 response regulator aspartate phosphatase H, N terminal CDC37_N PF03234.14 AAAP01003879.1_66 - 4 8.4 17.4 0.52 11.2 6.5 3.8 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding Spc7 PF08317.11 AAAP01003879.1_66 - 5.9 5.7 20.6 2.7 6.8 9.6 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 AAAP01003879.1_66 - 6.8 6.7 33.1 3.2 7.8 11.0 4.7 2 1 3 5 5 5 0 Laminin Domain II DUF155 PF02582.14 AAAP01003879.1_66 - 8.1 6.5 7.3 65 3.6 7.3 2.4 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Glyco_transf_41 PF13844.6 AAAP01003879.1_67 - 1.5e-89 300.7 0.0 3.3e-46 157.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_16 PF13432.6 AAAP01003879.1_67 - 6.5e-08 33.1 5.6 7.7e-05 23.3 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003879.1_67 - 1.3e-06 27.9 0.0 0.0031 17.3 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AAAP01003879.1_67 - 3.1e-06 26.8 0.1 0.19 11.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003879.1_67 - 5.1e-06 26.3 0.5 0.047 13.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003879.1_67 - 2e-05 24.3 1.0 0.04 14.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003879.1_67 - 2.4e-05 24.4 0.3 0.013 15.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003879.1_67 - 4.7e-05 23.0 12.3 5.3e-05 22.8 0.0 3.8 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.6 AAAP01003879.1_67 - 0.00095 19.4 1.7 0.4 11.0 0.6 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003879.1_67 - 0.011 16.3 0.0 0.8 10.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003879.1_67 - 0.011 16.2 0.4 0.045 14.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AAAP01003879.1_67 - 0.024 14.5 0.0 2.4 8.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 AAAP01003879.1_67 - 0.03 14.7 0.4 1.3 9.4 0.0 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat OKR_DC_1_N PF03709.15 AAAP01003879.1_67 - 0.075 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain TPR_14 PF13428.6 AAAP01003879.1_67 - 0.097 13.5 0.1 0.097 13.5 0.1 5.3 5 1 2 7 7 4 0 Tetratricopeptide repeat RVT_thumb PF06817.14 AAAP01003879.1_67 - 0.18 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Glyco_transf_41 PF13844.6 AAAP01003879.1_68 - 7.5e-87 291.7 0.0 1.4e-43 149.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_12 PF13424.6 AAAP01003879.1_68 - 1.3e-08 35.0 2.0 0.0011 19.2 0.5 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AAAP01003879.1_68 - 2e-08 33.8 0.2 4.2e-05 23.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AAAP01003879.1_68 - 2.5e-08 33.4 0.8 2.9e-05 23.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AAAP01003879.1_68 - 1.6e-07 31.6 8.1 0.002 18.8 0.0 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 AAAP01003879.1_68 - 6.3e-07 29.3 0.6 0.0063 16.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AAAP01003879.1_68 - 1.6e-06 27.7 0.4 0.00033 20.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AAAP01003879.1_68 - 1.1e-05 26.0 4.6 0.00013 22.6 0.2 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AAAP01003879.1_68 - 0.00018 22.0 3.8 0.0011 19.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AAAP01003879.1_68 - 0.00028 21.3 0.0 0.2 12.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 AAAP01003879.1_68 - 0.00073 19.9 5.4 0.057 14.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AAAP01003879.1_68 - 0.00088 18.9 1.9 0.0015 18.2 0.4 2.1 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 AAAP01003879.1_68 - 0.015 15.2 0.6 9.8 6.5 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 AAAP01003879.1_68 - 0.046 13.1 1.5 0.075 12.4 1.5 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_10 PF13374.6 AAAP01003879.1_68 - 0.072 13.0 3.0 2 8.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Epiglycanin_TR PF05647.11 AAAP01003879.1_69 - 0.45 10.5 26.7 0.037 13.9 9.0 3.3 1 1 2 3 3 3 0 Tandem-repeating region of mucin, epiglycanin-like Fibrinogen_BP PF08017.11 AAAP01003879.1_70 - 0.24 9.8 0.0 24 3.2 0.0 3.5 3 0 0 3 3 3 0 Fibrinogen binding protein Arc_PepC PF06819.11 AAAP01003879.1_70 - 1.1 9.5 53.0 26 5.0 0.0 22.2 21 9 5 29 29 29 0 Archaeal Peptidase A24 C-terminal Domain DUF4351 PF14261.6 AAAP01003879.1_71 - 0.12 12.5 76.8 14 5.9 0.4 23.9 7 5 18 26 26 26 0 Domain of unknown function (DUF4351) HTH_26 PF13443.6 AAAP01003879.1_71 - 3 8.4 111.5 1.8 9.0 0.3 24.9 4 3 23 28 28 28 0 Cro/C1-type HTH DNA-binding domain Radical_SAM PF04055.21 AAAP01003879.1_72 - 3.9e-12 46.8 0.0 6.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ANP PF00212.18 AAAP01003879.1_72 - 0.082 13.1 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Atrial natriuretic peptide B12-binding PF02310.19 AAAP01003879.1_72 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain Glycos_transf_1 PF00534.20 AAAP01003879.1_73 - 7.1e-06 25.7 0.0 1.5e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003879.1_73 - 8.2e-06 26.3 0.1 1.6e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase PF01370.21 AAAP01003879.1_74 - 2.2e-35 122.3 0.1 5.1e-35 121.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003879.1_74 - 2.5e-27 96.1 0.0 2.8e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01003879.1_74 - 1.2e-10 41.0 0.0 2.2e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAAP01003879.1_74 - 3.9e-07 29.5 0.0 5.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AAAP01003879.1_74 - 1.1e-05 24.7 0.0 3.4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 AAAP01003879.1_74 - 0.00016 21.7 0.0 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 AAAP01003879.1_74 - 0.00036 20.0 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 AAAP01003879.1_74 - 0.00049 19.2 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltr_RsmB-F PF01189.17 AAAP01003879.1_76 - 3.5e-49 167.2 0.0 5.1e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 AAAP01003879.1_76 - 4.2e-09 36.4 0.0 8.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003879.1_76 - 4e-08 33.8 0.8 1.2e-05 25.9 0.2 3.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003879.1_76 - 3.4e-07 29.8 0.0 4.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 AAAP01003879.1_76 - 0.00018 21.7 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 AAAP01003879.1_76 - 0.00038 20.3 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 AAAP01003879.1_76 - 0.00049 21.1 0.9 0.002 19.1 0.1 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 AAAP01003879.1_76 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_11 PF08241.12 AAAP01003879.1_76 - 0.0017 19.0 0.3 0.035 14.7 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AAAP01003879.1_76 - 0.007 15.9 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_3 PF01596.17 AAAP01003879.1_76 - 0.045 12.9 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase GCD14 PF08704.10 AAAP01003879.1_76 - 0.054 13.2 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit GA-like PF17573.2 AAAP01003879.1_76 - 0.063 13.2 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 GA-like domain PrmA PF06325.13 AAAP01003879.1_76 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 AAAP01003879.1_76 - 0.081 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 AAAP01003879.1_76 - 0.087 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003879.1_76 - 0.14 12.9 0.1 6.3 7.6 0.0 3.0 4 0 0 4 4 3 0 Methyltransferase domain SBP_bac_3 PF00497.20 AAAP01003879.1_77 - 1.5e-48 165.2 0.3 1.8e-48 164.9 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AAAP01003879.1_77 - 2.1e-05 24.2 0.4 3e-05 23.7 0.4 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 AAAP01003879.1_77 - 0.11 12.5 0.5 3.7 7.4 0.2 2.7 1 1 1 2 2 2 0 NMT1/THI5 like IMPDH PF00478.25 AAAP01003879.1_78 - 3.5e-160 532.7 9.4 4e-160 532.5 9.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AAAP01003879.1_78 - 1.5e-19 70.2 4.0 3.9e-12 46.4 0.1 3.1 3 0 0 3 3 2 2 CBS domain NMO PF03060.15 AAAP01003879.1_78 - 9.2e-13 48.3 8.8 5e-08 32.7 6.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AAAP01003879.1_78 - 4e-08 32.7 14.3 9.9e-08 31.4 12.7 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 AAAP01003879.1_78 - 6.4e-07 28.8 6.7 1.2e-06 28.0 6.7 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 AAAP01003879.1_78 - 8.7e-06 25.4 4.3 0.0051 16.3 0.3 2.6 1 1 0 2 2 2 2 Histidine biosynthesis protein IGPS PF00218.21 AAAP01003879.1_78 - 2.1e-05 23.8 0.6 0.059 12.5 0.0 2.6 3 0 0 3 3 3 2 Indole-3-glycerol phosphate synthase Dus PF01207.17 AAAP01003879.1_78 - 9.7e-05 21.6 1.1 0.021 13.9 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 AAAP01003879.1_78 - 0.0016 17.7 3.7 0.0077 15.4 3.7 2.2 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Beta_elim_lyase PF01212.21 AAAP01003879.1_78 - 0.0042 16.4 0.6 0.0078 15.5 0.6 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase PcrB PF01884.17 AAAP01003879.1_78 - 0.012 15.1 5.2 0.91 8.9 0.4 2.8 3 0 0 3 3 3 0 PcrB family G3P_antiterm PF04309.12 AAAP01003879.1_78 - 0.025 14.0 3.3 0.96 8.8 0.3 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 AAAP01003879.1_78 - 0.044 13.1 6.0 0.03 13.6 3.7 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase DHO_dh PF01180.21 AAAP01003879.1_78 - 0.057 12.6 7.5 0.21 10.8 2.2 2.3 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Cys_Met_Meta_PP PF01053.20 AAAP01003879.1_78 - 0.094 11.2 0.7 0.29 9.6 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Ribul_P_3_epim PF00834.19 AAAP01003879.1_78 - 0.27 10.6 4.6 0.22 10.9 2.4 2.1 2 1 0 2 2 2 0 Ribulose-phosphate 3 epimerase family FtsJ PF01728.19 AAAP01003879.1_79 - 4.4e-56 189.8 0.0 5.2e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 AAAP01003879.1_79 - 0.0055 16.5 0.0 2.8 7.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Ppx-GppA PF02541.16 AAAP01003879.1_80 - 4.6e-51 174.0 0.1 5.3e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Phage_integrase PF00589.22 AAAP01003879.1_81 - 6.3e-09 35.9 0.1 1.9e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AAAP01003879.1_81 - 0.0078 16.5 0.1 0.061 13.7 0.0 2.4 2 1 0 2 2 2 1 Phage integrase SAM-like domain Cation_efflux PF01545.21 AAAP01003879.1_82 - 2.6e-34 118.7 15.1 3.1e-34 118.5 15.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003879.1_82 - 1.1e-21 76.7 1.2 1.1e-21 76.7 1.2 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter HTH_17 PF12728.7 AAAP01003879.1_83 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 AAAP01003879.1_83 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Cation_efflux PF01545.21 AAAP01003879.1_85 - 1e-28 100.4 12.1 1.5e-28 99.9 12.1 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AAAP01003879.1_85 - 6.1e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4536 PF15055.6 AAAP01003879.1_85 - 0.098 12.9 1.6 0.17 12.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4536) Borrelia_P13 PF05628.12 AAAP01003879.1_85 - 0.91 9.5 3.7 1 9.3 0.4 2.3 1 1 1 2 2 2 0 Borrelia membrane protein P13 Mob_Pre PF01076.19 AAAP01003879.1_86 - 8.8e-13 48.5 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Plasmid recombination enzyme DUF3987 PF13148.6 AAAP01003879.1_87 - 2.9e-20 72.6 2.9 1.2e-17 64.0 1.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3987) HIRAN PF08797.11 AAAP01003879.1_88 - 1e-07 31.8 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 HIRAN domain Response_reg PF00072.24 AAAP01003879.1_89 - 7e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AAAP01003879.1_89 - 1.3e-20 73.2 0.0 3.3e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TrkA_N PF02254.18 AAAP01003879.1_89 - 0.14 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HATPase_c PF02518.26 AAAP01003879.1_90 - 7.6e-22 77.9 0.0 1.5e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AAAP01003879.1_90 - 6e-08 33.0 1.2 1.2e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AAAP01003879.1_90 - 2.9e-07 30.4 0.7 3.5e-06 26.9 0.5 2.7 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AAAP01003879.1_90 - 4e-05 23.5 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AAAP01003879.1_90 - 0.00055 19.9 0.9 0.00088 19.2 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain YtkA PF13115.6 AAAP01003879.1_91 - 5.5e-13 49.3 0.0 7.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 YtkA-like OEP PF02321.18 AAAP01003879.1_92 - 7.9e-39 133.4 18.5 3.5e-24 85.7 6.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_D23 PF16576.5 AAAP01003879.1_93 - 9e-80 266.9 0.1 1.3e-79 266.4 0.1 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AAAP01003879.1_93 - 3.6e-20 72.6 0.0 3.1e-15 56.8 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AAAP01003879.1_93 - 3.9e-08 33.0 0.6 1.3e-07 31.4 0.6 2.0 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AAAP01003879.1_93 - 0.00032 20.4 0.0 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D4 PF16572.5 AAAP01003879.1_93 - 0.041 13.8 0.7 0.43 10.5 0.7 2.4 1 1 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB ACR_tran PF00873.19 AAAP01003879.1_94 - 5.2e-233 775.9 11.5 6.1e-233 775.7 11.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Cytochrome_CBB3 PF13442.6 AAAP01003879.1_95 - 1.2e-13 51.2 1.2 2e-13 50.4 0.2 1.9 3 0 0 3 3 3 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AAAP01003879.1_95 - 0.00062 20.9 0.2 0.0013 19.8 0.1 1.7 1 1 0 1 1 1 1 Cytochrome c HD_5 PF13487.6 AAAP01003879.1_96 - 1.3e-18 67.0 0.1 3.5e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 HD domain HD PF01966.22 AAAP01003879.1_96 - 1.6e-17 63.8 0.1 3.7e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 HD domain Hpt PF01627.23 AAAP01003879.1_96 - 0.033 14.4 1.1 0.25 11.6 0.2 2.4 2 0 0 2 2 2 0 Hpt domain Helicase_C_3 PF13625.6 AAAP01003879.1_96 - 0.036 14.2 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain HD_6 PF18019.1 AAAP01003879.1_96 - 0.049 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 HD domain 4HB_MCP_1 PF12729.7 AAAP01003879.1_96 - 0.14 11.6 0.2 18 4.8 0.1 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF411 PF04214.13 AAAP01003879.1_97 - 9.3e-31 105.6 0.1 1.3e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF Glutaredoxin PF00462.24 AAAP01003879.1_97 - 0.00022 21.4 0.1 0.00036 20.7 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 AAAP01003879.1_97 - 0.008 16.6 0.1 0.01 16.2 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) CbiA PF01656.23 AAAP01003879.1_97 - 0.078 13.0 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF5065 PF16723.5 AAAP01003879.1_97 - 0.15 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) DUF4148 PF13663.6 AAAP01003879.1_98 - 0.0055 16.9 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4148) PSK PF06404.12 AAAP01003879.1_99 - 0.031 15.3 0.2 0.041 14.9 0.2 1.1 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) LPAM_1 PF08139.12 AAAP01003879.1_100 - 0.031 14.8 4.8 0.044 14.3 4.8 1.2 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DMP1 PF07263.11 AAAP01003879.1_100 - 0.067 12.1 0.0 0.078 11.9 0.0 1.0 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) Flg_bb_rod PF00460.20 AAAP01003879.1_101 - 3.1e-06 27.0 0.1 5.7e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AAAP01003879.1_102 - 5.1e-13 48.9 0.1 1.3e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AAAP01003879.1_102 - 1.8e-05 24.6 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Flagella basal body rod protein Methyltransf_11 PF08241.12 AAAP01003879.1_106 - 1.7e-14 54.2 0.0 2.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003879.1_106 - 1.2e-10 42.0 0.1 1.9e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003879.1_106 - 1.7e-10 41.0 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003879.1_106 - 8.6e-10 39.3 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003879.1_106 - 1.9e-09 37.5 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003879.1_106 - 0.00029 20.2 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AAAP01003879.1_106 - 0.01 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MCPsignal PF00015.21 AAAP01003880.1_1 - 2.3e-33 115.4 23.0 2.3e-33 115.4 23.0 1.5 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AAAP01003880.1_1 - 7.7e-05 22.9 11.0 0.39 11.0 0.5 4.0 1 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 AAAP01003880.1_1 - 0.059 13.2 6.1 0.4 10.5 5.9 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain GP41 PF00517.17 AAAP01003880.1_1 - 0.061 13.2 0.3 0.061 13.2 0.3 1.8 3 0 0 3 3 3 0 Retroviral envelope protein Laminin_II PF06009.12 AAAP01003880.1_1 - 0.081 12.9 8.5 0.099 12.7 1.0 2.9 1 1 3 4 4 4 0 Laminin Domain II LPP PF04728.13 AAAP01003880.1_1 - 0.09 13.2 12.3 14 6.1 0.3 4.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 AAAP01003880.1_1 - 0.096 12.7 4.3 2.1 8.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 AAAP01003880.1_1 - 0.12 11.4 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Syntaxin_2 PF14523.6 AAAP01003880.1_1 - 0.13 12.6 0.0 1.7 9.0 0.0 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Gloverin PF10793.9 AAAP01003880.1_1 - 0.16 11.9 1.1 0.23 11.3 0.6 1.6 1 1 0 1 1 1 0 Gloverin-like protein DUF2203 PF09969.9 AAAP01003880.1_1 - 0.66 10.7 3.5 13 6.5 0.2 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 AAAP01003880.1_1 - 1.6 9.2 3.5 24 5.4 0.3 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) ABC2_membrane_3 PF12698.7 AAAP01003880.1_2 - 3.1e-46 158.1 0.5 3.5e-46 157.9 0.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AAAP01003880.1_2 - 2.3e-37 128.5 22.1 7.5e-35 120.2 16.7 2.4 2 1 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AAAP01003880.1_2 - 4.8e-25 88.4 6.0 6.2e-25 88.1 6.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AAAP01003880.1_2 - 4.3e-07 30.1 9.5 2.1e-06 27.8 8.0 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 AAAP01003880.1_3 - 2.8e-31 108.8 0.0 3.7e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AAAP01003880.1_3 - 2.6e-10 40.6 0.4 6.9e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AAAP01003880.1_3 - 7.5e-05 23.3 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAAP01003880.1_3 - 0.0035 17.7 0.0 0.0073 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AAAP01003880.1_3 - 0.01 15.3 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AAAP01003880.1_3 - 0.015 15.0 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 AAAP01003880.1_3 - 0.027 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CysG_dimeriser PF10414.9 AAAP01003880.1_3 - 0.045 13.5 0.3 3.2 7.5 0.0 3.0 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region SbcCD_C PF13558.6 AAAP01003880.1_3 - 0.045 14.0 0.0 0.74 10.1 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 AAAP01003880.1_3 - 0.06 13.5 0.1 0.1 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AAAP01003880.1_3 - 0.22 11.1 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain HlyD_3 PF13437.6 AAAP01003880.1_4 - 1.9e-13 51.0 0.1 8.7e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AAAP01003880.1_4 - 2.5e-06 26.9 0.0 0.00032 20.0 0.0 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AAAP01003880.1_4 - 1.4e-05 24.8 3.9 0.0017 18.1 0.4 3.1 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AAAP01003880.1_4 - 0.00083 19.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme DUF3584 PF12128.8 AAAP01003880.1_4 - 0.16 9.5 6.9 0.2 9.2 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) POR PF01558.18 AAAP01003880.1_5 - 1.4e-13 51.3 0.1 2.5e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 AAAP01003880.1_6 - 3.4e-18 65.9 0.3 6.5e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 AAAP01003880.1_6 - 0.028 14.1 1.0 0.31 10.6 0.3 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fer4_10 PF13237.6 AAAP01003880.1_6 - 1.8 8.7 5.8 0.31 11.2 1.7 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain ECH_1 PF00378.20 AAAP01003880.1_7 - 9.5e-64 215.1 0.1 1.1e-63 214.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003880.1_7 - 1.6e-31 110.0 0.7 5.4e-28 98.4 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase 4HBT_2 PF13279.6 AAAP01003880.1_8 - 5.8e-08 33.3 0.0 7.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AAAP01003880.1_8 - 0.00012 22.4 0.0 0.00031 21.0 0.0 1.8 1 1 0 1 1 1 1 Thioesterase superfamily DUF3305 PF11749.8 AAAP01003880.1_8 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) NAD_binding_1 PF00175.21 AAAP01003880.1_9 - 5.3e-15 56.0 0.0 9.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4 PF00037.27 AAAP01003880.1_9 - 1.3e-14 53.2 14.8 2.1e-07 30.5 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AAAP01003880.1_9 - 6.1e-10 39.1 11.4 1e-09 38.4 11.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AAAP01003880.1_9 - 6.6e-09 36.6 5.8 0.0012 19.7 1.4 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AAAP01003880.1_9 - 1.6e-08 34.6 11.8 2.8e-08 33.8 11.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AAAP01003880.1_9 - 5.7e-08 33.2 14.1 1.2e-07 32.2 14.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_6 PF00970.24 AAAP01003880.1_9 - 4e-07 30.3 0.0 7.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer4_6 PF12837.7 AAAP01003880.1_9 - 6.1e-07 29.3 15.9 0.0013 18.7 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AAAP01003880.1_9 - 1.2e-06 28.5 15.0 9e-06 25.7 15.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003880.1_9 - 1.6e-06 27.8 15.9 0.0017 18.4 4.4 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003880.1_9 - 0.00039 20.7 15.6 0.059 13.9 4.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003880.1_9 - 0.00054 20.7 18.3 0.037 15.0 4.1 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AAAP01003880.1_9 - 0.055 14.0 14.6 0.65 10.6 2.9 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003880.1_9 - 0.059 13.8 15.8 2 8.9 4.3 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_11 PF13247.6 AAAP01003880.1_9 - 0.21 11.8 5.8 0.35 11.0 5.8 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003880.1_9 - 3.7 8.1 17.0 3.2 8.4 2.3 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AAAP01003880.1_9 - 9.3 6.5 12.9 4.7 7.5 2.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PaaA_PaaC PF05138.12 AAAP01003880.1_10 - 0.0074 15.5 0.0 0.018 14.2 0.0 1.7 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein CcdA PF07362.12 AAAP01003880.1_10 - 0.13 12.7 0.1 0.37 11.3 0.1 1.7 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA ECH_1 PF00378.20 AAAP01003880.1_11 - 7e-20 71.4 0.0 2.1e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AAAP01003880.1_11 - 3.3e-09 36.7 0.0 5.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 AAAP01003880.1_12 - 2e-61 207.9 0.1 2.3e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_6 PF12697.7 AAAP01003880.1_13 - 9.7e-16 59.0 5.5 1.7e-15 58.2 5.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AAAP01003880.1_13 - 6.9e-10 39.0 0.4 1.5e-08 34.6 0.3 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AAAP01003880.1_13 - 7.3e-09 35.2 0.1 7.5e-05 22.1 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 AAAP01003880.1_13 - 0.0033 17.6 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 AAAP01003880.1_13 - 0.011 15.3 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ndr PF03096.14 AAAP01003880.1_13 - 0.019 13.7 0.0 0.51 9.0 0.0 2.0 2 0 0 2 2 2 0 Ndr family Tnp_DNA_bind PF14706.6 AAAP01003880.1_13 - 0.038 13.9 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Transposase DNA-binding DUF4863 PF16155.5 AAAP01003880.1_14 - 4.6e-53 179.2 0.0 5.2e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) Molybdopterin PF00384.22 AAAP01003880.1_15 - 3.1e-86 290.0 0.0 3.8e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AAAP01003880.1_15 - 2.4e-24 85.5 0.0 8.9e-24 83.7 0.0 2.0 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Fer2_4 PF13510.6 AAAP01003880.1_15 - 8.1e-16 57.8 0.5 1.9e-15 56.6 0.1 1.9 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Molybdop_Fe4S4 PF04879.16 AAAP01003880.1_15 - 6.8e-14 51.6 0.4 1.9e-13 50.1 0.4 1.9 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4_21 PF14697.6 AAAP01003880.1_15 - 3.5e-07 30.2 22.4 1.7e-06 28.1 9.6 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AAAP01003880.1_15 - 3.8e-06 26.5 4.8 3.8e-06 26.5 4.8 3.5 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_7 PF12838.7 AAAP01003880.1_15 - 4e-06 27.3 27.3 2.1e-05 25.0 10.8 3.1 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 AAAP01003880.1_15 - 4.8e-06 27.0 5.8 1.9e-05 25.1 5.8 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AAAP01003880.1_15 - 5.3e-06 26.8 5.1 5.3e-06 26.8 5.1 2.5 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 AAAP01003880.1_15 - 7.3e-06 25.8 0.2 2e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_6 PF12837.7 AAAP01003880.1_15 - 1.1e-05 25.2 19.3 7.9e-05 22.6 3.5 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AAAP01003880.1_15 - 1.3e-05 25.3 9.3 1.3e-05 25.3 9.3 3.1 2 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AAAP01003880.1_15 - 2e-05 24.6 26.5 4.2e-05 23.6 11.0 2.5 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AAAP01003880.1_15 - 0.0093 16.0 4.4 0.0093 16.0 4.4 4.0 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_3 PF12798.7 AAAP01003880.1_15 - 0.013 16.4 7.9 0.013 16.4 7.9 4.0 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_4 PF12800.7 AAAP01003880.1_15 - 0.017 15.6 20.4 0.035 14.6 4.6 3.7 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 AAAP01003880.1_15 - 0.021 15.6 1.7 0.021 15.6 1.7 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AAAP01003880.1_15 - 0.11 13.3 8.0 1.4 9.7 0.5 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain CDC48_N PF02359.18 AAAP01003880.1_15 - 0.17 12.1 0.0 0.65 10.2 0.0 1.9 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain Fer4_16 PF13484.6 AAAP01003880.1_15 - 0.27 12.2 14.7 0.059 14.3 5.4 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AAAP01003880.1_15 - 0.51 10.5 11.6 0.62 10.3 1.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AAAP01003880.1_15 - 3.1 8.4 12.4 8.6 7.0 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Complex1_51K PF01512.17 AAAP01003880.1_16 - 4.6e-44 150.0 0.0 7.9e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AAAP01003880.1_16 - 2e-21 75.8 0.0 4.3e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 2Fe-2S_thioredx PF01257.19 AAAP01003880.1_16 - 2.5e-13 50.1 0.0 1.1e-09 38.3 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like [2Fe-2S] ferredoxin SLBB PF10531.9 AAAP01003880.1_16 - 3.4e-08 33.2 0.4 3e-07 30.2 0.1 2.4 2 0 0 2 2 2 1 SLBB domain SKI PF01202.22 AAAP01003880.1_17 - 5.9e-28 98.0 0.0 8.7e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase HTH_31 PF13560.6 AAAP01003880.1_17 - 5e-10 39.6 0.5 1.6e-09 37.9 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AAAP01003880.1_17 - 7.1e-09 35.6 0.0 2.7e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 AAAP01003880.1_17 - 2.1e-07 30.9 0.1 1e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AAAP01003880.1_17 - 6.4e-06 26.5 0.1 1.8e-05 25.1 0.0 1.8 2 0 0 2 2 1 1 Cro/C1-type HTH DNA-binding domain AAA_18 PF13238.6 AAAP01003880.1_17 - 0.00063 20.3 0.0 0.0023 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAAP01003880.1_17 - 0.001 19.2 0.0 0.0026 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain HTH_25 PF13413.6 AAAP01003880.1_17 - 0.0019 18.0 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Cytidylate_kin2 PF13189.6 AAAP01003880.1_17 - 0.0038 17.4 0.1 0.21 11.7 0.0 2.7 2 1 0 2 2 2 1 Cytidylate kinase-like family AAA PF00004.29 AAAP01003880.1_17 - 0.0076 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AAAP01003880.1_17 - 0.0097 16.4 0.1 0.029 14.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.13 AAAP01003880.1_17 - 0.023 13.9 0.1 0.081 12.1 0.1 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF815) TsaE PF02367.17 AAAP01003880.1_17 - 0.048 13.6 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AAAP01003880.1_17 - 0.061 13.7 0.3 0.12 12.7 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AAAP01003880.1_17 - 0.085 13.1 0.1 0.18 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 AAAP01003880.1_17 - 0.1 11.9 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 AAAP01003880.1_17 - 0.13 12.4 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 AAAP01003880.1_17 - 0.14 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Peptidase_S66 PF02016.15 AAAP01003880.1_18 - 3.8e-21 75.4 0.0 5.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 AAAP01003880.1_18 - 3.5e-17 63.1 0.0 5.6e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Mur_ligase_M PF08245.12 AAAP01003880.1_19 - 5.7e-20 72.1 0.0 8.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AAAP01003880.1_19 - 2e-14 53.7 0.0 1.6e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AAAP01003880.1_19 - 7.9e-11 42.1 0.1 4.8e-10 39.6 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain CrgA PF06781.12 AAAP01003880.1_20 - 0.063 13.3 6.0 0.099 12.7 0.1 3.5 3 0 0 3 3 3 0 Cell division protein CrgA DUF992 PF06186.11 AAAP01003880.1_21 - 1.1e-29 103.2 4.6 1.3e-29 102.9 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF992) Cupin_2 PF07883.11 AAAP01003880.1_22 - 0.002 17.8 0.2 0.015 15.0 0.2 2.3 1 1 0 1 1 1 1 Cupin domain AbrB PF05145.12 AAAP01003880.1_23 - 9.3e-83 277.8 42.1 1.3e-82 277.3 42.1 1.2 1 0 0 1 1 1 1 Transition state regulatory protein AbrB NAD_kinase PF01513.21 AAAP01003880.1_24 - 4.1e-19 68.9 0.0 5.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AAAP01003880.1_24 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain HAD_2 PF13419.6 AAAP01003880.1_27 - 1e-35 123.4 0.0 1.2e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003880.1_27 - 7.2e-15 55.8 0.0 2e-14 54.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003880.1_27 - 7.2e-05 22.8 0.1 0.00012 22.1 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 AAAP01003880.1_27 - 0.00041 20.1 0.1 0.003 17.3 0.0 2.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 AAAP01003880.1_27 - 0.0039 17.6 0.0 0.005 17.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01003880.1_27 - 0.076 13.1 0.5 2.4 8.3 0.5 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Band_7_1 PF13421.6 AAAP01003880.1_27 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family NTP_transf_3 PF12804.7 AAAP01003880.1_28 - 5.9e-11 43.0 0.0 7.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AAAP01003880.1_28 - 3.1e-09 36.8 0.0 3.9e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transferase PF00483.23 AAAP01003880.1_29 - 2.4e-13 50.3 0.0 3.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AAAP01003880.1_29 - 1.5e-08 35.2 0.2 2.1e-08 34.7 0.1 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003880.1_29 - 0.00042 20.1 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MBOAT PF03062.19 AAAP01003880.1_30 - 2e-32 112.9 4.8 2e-32 112.9 4.8 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AAAP01003880.1_30 - 1.3e-06 28.6 1.9 4.5e-06 26.8 1.9 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Mob_synth_C PF06463.13 AAAP01003880.1_32 - 1.2e-41 141.6 0.0 1.8e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AAAP01003880.1_32 - 8.4e-26 91.3 0.0 1.3e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01003880.1_32 - 1.1e-07 32.2 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003880.1_32 - 4.1e-06 26.9 0.0 1.6e-05 25.0 0.0 2.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain DUF2478 PF10649.9 AAAP01003880.1_33 - 1.7e-51 174.0 0.0 4.1e-51 172.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) DUF364 PF04016.12 AAAP01003880.1_33 - 1.6e-29 102.3 0.0 2.6e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Putative heavy-metal chelation DUF4213 PF13938.6 AAAP01003880.1_33 - 1.2e-18 67.1 0.2 2.9e-18 65.9 0.2 1.7 1 0 0 1 1 1 1 Putative heavy-metal chelation NTPase_1 PF03266.15 AAAP01003880.1_33 - 0.032 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 NTPase Polysacc_deac_1 PF01522.21 AAAP01003880.1_34 - 5.5e-23 81.2 0.0 7.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glycos_transf_1 PF00534.20 AAAP01003880.1_35 - 2.2e-34 118.5 0.0 3.7e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003880.1_35 - 1.7e-28 99.7 0.4 7.6e-28 97.6 0.5 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003880.1_35 - 3.9e-10 40.0 0.3 8.7e-10 38.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01003880.1_35 - 8.1e-10 39.0 0.1 1.6e-08 34.8 0.1 2.3 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003880.1_35 - 3.7e-05 24.2 3.0 3.7e-05 24.2 3.0 3.0 2 2 1 3 3 3 1 Glycosyl transferase 4-like domain Gemini_V2 PF01524.17 AAAP01003880.1_35 - 0.046 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Geminivirus V2 protein Glyco_trans_4_2 PF13477.6 AAAP01003880.1_35 - 0.053 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glycos_transf_2 PF00535.26 AAAP01003880.1_36 - 6.7e-09 35.8 0.2 1.4e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_36 - 0.00017 21.5 0.5 0.00082 19.3 0.2 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003880.1_36 - 0.00064 20.2 0.2 0.0032 18.0 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 RHH_1 PF01402.21 AAAP01003880.1_37 - 4.8e-10 39.0 0.1 4.8e-10 39.0 0.1 2.0 3 0 0 3 3 3 1 Ribbon-helix-helix protein, copG family RHH_5 PF07878.11 AAAP01003880.1_37 - 0.003 17.4 0.5 0.0076 16.1 0.0 1.8 2 0 0 2 2 2 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 BrnA_antitoxin PF14384.6 AAAP01003880.1_37 - 0.072 13.6 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system ParE_toxin PF05016.15 AAAP01003880.1_38 - 6.6e-10 39.5 0.0 7.2e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Glyco_trans_1_4 PF13692.6 AAAP01003880.1_39 - 4.2e-10 40.2 0.1 7.2e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003880.1_39 - 4.3e-06 26.4 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003880.1_39 - 4.7e-06 26.7 0.2 9e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AAAP01003880.1_39 - 0.00019 21.7 0.2 0.0004 20.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AAAP01003880.1_39 - 0.0016 18.9 1.5 0.0016 18.9 1.5 2.3 1 1 0 2 2 2 1 Glycosyl transferase 4-like domain Wzy_C PF04932.15 AAAP01003880.1_40 - 8.7e-13 48.2 1.5 8.7e-13 48.2 1.5 5.2 2 2 3 5 5 5 1 O-Antigen ligase DUF460 PF04312.13 AAAP01003880.1_40 - 0.16 11.6 0.2 0.27 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Radical_SAM PF04055.21 AAAP01003880.1_41 - 3.4e-08 34.0 0.0 6.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AAAP01003880.1_41 - 1.4e-07 31.9 0.1 3.3e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Methyltransf_21 PF05050.12 AAAP01003880.1_42 - 4.2e-12 46.4 0.0 5.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_trans_4_4 PF13579.6 AAAP01003880.1_43 - 3.5e-06 27.5 8.9 3.5e-06 27.5 8.9 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01003880.1_43 - 6.5e-06 26.3 2.2 9.3e-05 22.5 2.2 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Asn_synthase PF00733.21 AAAP01003880.1_44 - 1.8e-72 245.0 0.0 2.1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003880.1_44 - 1.9e-41 140.8 0.0 2.9e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003880.1_44 - 1.7e-38 131.9 0.0 2.8e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAAP01003880.1_44 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Methyltr_RsmB-F PF01189.17 AAAP01003880.1_45 - 3.8e-43 147.5 0.0 5.3e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 AAAP01003880.1_45 - 3.1e-21 76.0 0.0 4.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 NusB family Methyltransf_31 PF13847.6 AAAP01003880.1_45 - 1.1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003880.1_45 - 1.8e-05 25.4 0.1 0.00015 22.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAAP01003880.1_45 - 0.0012 18.4 0.0 0.0089 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 AAAP01003880.1_45 - 0.054 14.1 0.0 0.31 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 AAAP01003880.1_45 - 0.061 13.4 0.5 1 9.4 0.3 2.7 2 1 0 2 2 2 0 FtsJ-like methyltransferase Hydrolase_like PF13242.6 AAAP01003880.1_46 - 7.1e-15 54.8 0.1 1.1e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AAAP01003880.1_46 - 9e-09 35.7 0.0 7.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 AAAP01003880.1_46 - 4.1e-05 23.3 0.0 4.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.26 AAAP01003880.1_46 - 0.00067 20.0 0.0 0.0021 18.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01003880.1_46 - 0.00073 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_trans_4_4 PF13579.6 AAAP01003880.1_47 - 6e-20 72.3 2.7 6e-20 72.3 2.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AAAP01003880.1_47 - 6.3e-19 68.6 0.3 1.2e-18 67.7 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AAAP01003880.1_47 - 5.2e-16 58.7 0.0 8.8e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AAAP01003880.1_47 - 8.1e-14 52.2 0.1 2.6e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003880.1_47 - 0.00016 22.0 2.2 0.00037 20.8 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 UDPG_MGDP_dh_N PF03721.14 AAAP01003880.1_48 - 5.1e-32 111.0 0.0 7.8e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AAAP01003880.1_48 - 1.4e-21 76.5 0.0 2.4e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AAAP01003880.1_48 - 1.7e-18 67.0 0.0 3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 AAAP01003880.1_48 - 0.0019 18.4 0.0 0.017 15.3 0.0 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_4 PF13439.6 AAAP01003880.1_48 - 0.11 12.5 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_9 PF01075.17 AAAP01003880.1_49 - 1.4e-26 93.4 0.0 4.2e-26 91.8 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_trans_1_4 PF13692.6 AAAP01003880.1_50 - 1.9e-26 93.1 0.0 3e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AAAP01003880.1_50 - 2.7e-26 92.1 0.0 3.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AAAP01003880.1_50 - 7.9e-14 51.8 0.0 9.7e-13 48.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AAAP01003880.1_50 - 0.00013 22.0 0.8 0.00071 19.6 0.9 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_2 PF00535.26 AAAP01003880.1_51 - 6.5e-34 117.2 0.1 9.1e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_51 - 1.8e-14 54.2 0.0 2.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003880.1_51 - 2.1e-07 30.7 0.0 2.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003880.1_51 - 6.3e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AAAP01003880.1_51 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cupin_2 PF07883.11 AAAP01003880.1_52 - 1.5e-06 27.8 0.1 2.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AAAP01003880.1_52 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 AAAP01003880.1_52 - 0.058 13.0 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin FdtA PF05523.11 AAAP01003880.1_52 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal Methyltransf_14 PF08484.11 AAAP01003880.1_53 - 1.5e-53 180.9 0.0 2.1e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 AAAP01003880.1_53 - 1.9e-21 76.1 1.2 2.9e-21 75.4 1.2 1.3 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 AAAP01003880.1_53 - 2.1e-13 50.4 0.0 3.2e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_53 - 1e-07 32.6 0.0 2.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003880.1_53 - 1.5e-06 28.8 0.0 3.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003880.1_53 - 8.6e-05 23.2 0.0 0.00019 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAAP01003880.1_53 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 AAAP01003880.1_53 - 0.029 14.2 0.0 0.12 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 AAAP01003880.1_54 - 1.4e-43 149.1 0.0 1.8e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_54 - 2.4e-31 109.4 0.0 3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003880.1_54 - 1e-12 47.7 0.0 1.9e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01003880.1_54 - 1.2e-07 31.2 0.0 2.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003880.1_54 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003880.1_54 - 0.0013 18.0 0.0 0.7 9.0 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.22 AAAP01003880.1_55 - 4e-23 82.5 0.1 5.6e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 AAAP01003880.1_55 - 0.0097 16.6 0.1 0.014 16.1 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 AAAP01003880.1_55 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.17 AAAP01003880.1_55 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain GDP_Man_Dehyd PF16363.5 AAAP01003880.1_56 - 4.3e-48 164.4 0.0 1.1e-47 163.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003880.1_56 - 4.3e-44 150.8 0.0 5.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AAAP01003880.1_56 - 4.1e-09 36.0 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003880.1_56 - 9.6e-06 24.9 0.0 2.3e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01003880.1_56 - 1.1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01003880.1_56 - 3.7e-05 23.0 0.0 0.053 12.7 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 AAAP01003880.1_56 - 0.0066 15.9 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase SecM PF06558.12 AAAP01003880.1_56 - 0.1 12.7 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Acetyltransf_6 PF13480.7 AAAP01003880.1_57 - 3.2e-15 56.5 1.2 5.9e-15 55.7 1.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 AAAP01003880.1_57 - 5.4e-11 42.0 0.0 1.4e-07 30.7 0.0 2.3 3 0 0 3 3 3 2 FemAB family DegT_DnrJ_EryC1 PF01041.17 AAAP01003880.1_58 - 4e-09 36.2 0.0 6.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AAAP01003880.1_58 - 0.043 12.8 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Asn_synthase PF00733.21 AAAP01003880.1_59 - 1.1e-78 265.4 0.0 1.4e-78 265.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003880.1_59 - 4.4e-44 149.3 0.0 2.4e-43 147.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003880.1_59 - 5.9e-40 136.6 0.0 4.6e-39 133.7 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AAAP01003880.1_59 - 0.0051 16.0 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 AAAP01003880.1_59 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein tRNA_Me_trans PF03054.16 AAAP01003880.1_59 - 0.091 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.21 AAAP01003880.1_60 - 3.3e-81 273.7 0.0 5.2e-81 273.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003880.1_60 - 3.6e-37 127.0 0.0 5.6e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003880.1_60 - 7.1e-27 94.2 0.0 1.8e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AAAP01003880.1_60 - 0.24 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein 2-Hacid_dh_C PF02826.19 AAAP01003880.1_61 - 1.3e-56 190.7 0.0 1.8e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01003880.1_61 - 1.2e-16 60.6 0.0 1.6e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 AAAP01003880.1_61 - 4e-05 23.8 0.0 6.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 AAAP01003880.1_61 - 7e-05 23.0 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 AAAP01003880.1_61 - 8e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 AAAP01003880.1_61 - 0.012 16.2 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 AAAP01003880.1_61 - 0.014 15.9 0.1 0.025 15.1 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 AAAP01003880.1_61 - 0.11 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAD_2 PF13419.6 AAAP01003880.1_62 - 1.4e-37 129.5 0.0 1.6e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003880.1_62 - 2.5e-19 70.4 0.1 3.2e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003880.1_62 - 2.1e-13 51.1 0.4 2.6e-13 50.8 0.4 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AAAP01003880.1_62 - 1.1e-08 35.0 0.1 2.7e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 AAAP01003880.1_62 - 0.0032 17.2 0.0 2.1 8.1 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase_3 PF08282.12 AAAP01003880.1_62 - 0.0084 15.9 0.0 2.2 7.9 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AAAP01003880.1_62 - 0.024 14.7 0.0 0.35 11.0 0.0 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase KfrA_N PF11740.8 AAAP01003880.1_62 - 0.055 14.1 0.2 0.091 13.4 0.2 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term PNK3P PF08645.11 AAAP01003880.1_62 - 0.15 11.8 0.0 23 4.6 0.0 2.9 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DUF2608 PF11019.8 AAAP01003880.1_62 - 0.22 11.0 0.0 13 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) CTP_transf_3 PF02348.19 AAAP01003880.1_63 - 2.9e-30 105.8 0.0 3.6e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01003880.1_63 - 5.9e-11 43.0 0.0 8.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_63 - 0.054 13.4 0.1 0.14 12.0 0.0 1.8 2 1 0 2 2 2 0 Glycosyltransferase like family 2 GFO_IDH_MocA PF01408.22 AAAP01003880.1_64 - 1.3e-14 55.1 0.0 2.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAAP01003880.1_64 - 4.7e-05 23.4 0.1 9e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 AAAP01003880.1_64 - 0.0013 19.1 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ox_reductase_C PF08635.10 AAAP01003880.1_64 - 0.015 15.0 0.0 0.034 13.8 0.0 1.7 1 1 0 1 1 1 0 Putative oxidoreductase C terminal domain NAD_binding_3 PF03447.16 AAAP01003880.1_64 - 0.13 12.9 0.1 0.43 11.2 0.1 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AAAP01003880.1_65 - 1.1e-19 71.4 0.0 1.9e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAAP01003880.1_65 - 8.5e-14 51.6 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ox_reductase_C PF08635.10 AAAP01003880.1_65 - 9.3e-05 22.1 0.0 0.0095 15.6 0.0 2.2 1 1 1 2 2 2 2 Putative oxidoreductase C terminal domain Gp_dh_N PF00044.24 AAAP01003880.1_65 - 0.061 13.7 0.0 0.29 11.5 0.0 2.1 1 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_21 PF05050.12 AAAP01003880.1_67 - 1.7e-18 67.2 0.0 2.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 AAAP01003880.1_67 - 1.7e-07 30.8 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_25 PF13649.6 AAAP01003880.1_67 - 0.0067 17.1 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AAAP01003880.1_67 - 0.017 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 AAAP01003880.1_67 - 0.037 13.6 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FA_synthesis PF02504.15 AAAP01003880.1_67 - 0.043 12.9 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein Methyltransf_23 PF13489.6 AAAP01003880.1_67 - 0.044 13.6 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003880.1_67 - 0.053 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003880.1_67 - 0.18 12.4 0.0 0.3 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Radical_SAM PF04055.21 AAAP01003880.1_69 - 1.5e-21 77.5 0.0 5.2e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003880.1_69 - 2.5e-20 72.7 0.0 4.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain PhyH PF05721.13 AAAP01003880.1_70 - 0.033 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Radical_SAM PF04055.21 AAAP01003880.1_72 - 5.2e-22 79.0 0.0 1.3e-20 74.4 0.0 2.1 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AAAP01003880.1_72 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003880.1_72 - 1.6e-05 25.1 0.1 3.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain SPASM PF13186.6 AAAP01003880.1_72 - 2.9e-05 24.5 0.1 7.5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain GTPase_binding PF09027.10 AAAP01003880.1_72 - 0.034 14.1 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 GTPase binding ABC_tran PF00005.27 AAAP01003880.1_74 - 1e-30 107.0 0.0 5.6e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AAAP01003880.1_74 - 3.4e-06 26.7 0.3 0.00012 21.6 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MeaB PF03308.16 AAAP01003880.1_74 - 3.2e-05 23.1 0.3 5e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 AAAP01003880.1_74 - 3.3e-05 23.5 0.7 6.9e-05 22.5 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 AAAP01003880.1_74 - 0.0069 16.3 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 NTPase T2SSE PF00437.20 AAAP01003880.1_74 - 0.0092 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 AAAP01003880.1_74 - 0.028 14.8 0.1 0.065 13.6 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 AAAP01003880.1_74 - 0.041 13.2 0.2 0.076 12.3 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.6 AAAP01003880.1_74 - 0.062 13.5 0.5 0.35 11.1 0.5 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 AAAP01003880.1_74 - 0.11 12.6 1.5 0.19 11.8 1.5 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 AAAP01003880.1_74 - 0.12 12.2 0.2 4 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 AAAP01003880.1_74 - 0.17 12.0 0.3 0.35 11.0 0.3 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AAAP01003880.1_74 - 0.17 11.8 0.3 0.34 10.8 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 AAAP01003880.1_74 - 0.21 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 AAAP01003880.1_74 - 0.22 11.2 1.0 1.6 8.4 1.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AAAP01003880.1_74 - 0.33 11.4 0.7 0.61 10.5 0.7 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_11 PF08241.12 AAAP01003880.1_75 - 9e-17 61.5 0.0 1.9e-16 60.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003880.1_75 - 8.9e-16 58.4 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003880.1_75 - 1.2e-15 57.6 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003880.1_75 - 1.9e-09 37.6 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_75 - 9.8e-09 35.9 0.0 1.9e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AAAP01003880.1_75 - 2.9e-05 23.7 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 AAAP01003880.1_75 - 5.1e-05 22.7 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAAP01003880.1_75 - 6.9e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AAAP01003880.1_75 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 AAAP01003880.1_75 - 0.0007 18.3 0.0 0.00089 17.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 AAAP01003880.1_75 - 0.0029 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 AAAP01003880.1_75 - 0.0035 16.8 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 AAAP01003880.1_75 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 AAAP01003880.1_75 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 AAAP01003880.1_75 - 0.049 13.0 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 AAAP01003880.1_75 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 AAAP01003880.1_75 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF2309 PF10070.9 AAAP01003880.1_75 - 0.16 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) RmlD_sub_bind PF04321.17 AAAP01003880.1_76 - 1.1e-34 119.8 0.0 1.4e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AAAP01003880.1_76 - 5.8e-09 35.8 0.0 9.3e-09 35.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.26 AAAP01003880.1_77 - 6.3e-36 123.7 0.0 9.7e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_77 - 5.9e-11 42.7 0.0 9.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003880.1_77 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 EutH PF04346.12 AAAP01003880.1_77 - 0.00017 20.9 0.4 0.00024 20.4 0.4 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH DUF4282 PF14110.6 AAAP01003880.1_77 - 0.23 12.2 3.3 0.42 11.4 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Asn_synthase PF00733.21 AAAP01003880.1_78 - 6.8e-76 256.2 0.0 9.9e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AAAP01003880.1_78 - 9.5e-45 151.5 0.0 1.5e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AAAP01003880.1_78 - 1e-39 135.8 0.0 2.8e-39 134.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AAAP01003880.1_78 - 0.022 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein ATP_bind_3 PF01171.20 AAAP01003880.1_78 - 0.029 14.1 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 PP-loop family DUF1933 PF09147.10 AAAP01003880.1_78 - 0.11 12.1 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) YqjK PF13997.6 AAAP01003880.1_79 - 0.044 14.0 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 YqjK-like protein Radical_SAM PF04055.21 AAAP01003880.1_80 - 2.2e-19 70.4 0.1 2.4e-18 67.1 0.0 2.2 2 1 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003880.1_80 - 2.3e-13 50.2 0.0 4.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain Fer4_12 PF13353.6 AAAP01003880.1_80 - 0.0093 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AAAP01003880.1_80 - 0.095 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Methyltransf_11 PF08241.12 AAAP01003880.1_81 - 1.5e-21 76.8 0.0 3.2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003880.1_81 - 8.6e-21 74.5 0.0 4.3e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003880.1_81 - 6.1e-12 45.6 0.0 9.8e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_81 - 7.6e-12 45.9 0.0 3.2e-11 43.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 AAAP01003880.1_81 - 2.5e-10 40.1 0.0 3.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AAAP01003880.1_81 - 6.1e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AAAP01003880.1_81 - 0.019 14.8 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Hexapep PF00132.24 AAAP01003880.1_83 - 2.1e-16 58.9 12.9 1.4e-06 27.8 0.3 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003880.1_83 - 3.1e-10 39.6 14.4 6.6e-06 25.8 2.2 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase MBOAT PF03062.19 AAAP01003880.1_84 - 1.6e-25 90.2 5.8 3.6e-25 89.0 5.8 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Mur_ligase PF01225.25 AAAP01003880.1_85 - 0.093 13.1 0.0 0.33 11.3 0.0 1.9 1 1 0 1 1 1 0 Mur ligase family, catalytic domain DUF1574 PF07611.11 AAAP01003880.1_85 - 0.18 11.1 0.0 0.92 8.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) adh_short_C2 PF13561.6 AAAP01003880.1_86 - 3e-28 99.0 0.0 3.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003880.1_86 - 2e-20 73.1 0.0 3.2e-20 72.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AAAP01003880.1_86 - 0.0001 21.9 0.0 0.0017 17.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 AAAP01003880.1_86 - 0.058 13.5 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 AAAP01003880.1_86 - 0.097 11.7 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 AAAP01003880.1_86 - 0.11 11.6 0.0 0.82 8.8 0.1 1.9 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 AAAP01003880.1_86 - 0.15 12.0 0.3 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 KR domain MBOAT PF03062.19 AAAP01003880.1_88 - 1.6e-28 100.0 6.5 1.6e-28 100.0 6.5 2.4 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AAAP01003880.1_88 - 1.4e-06 28.4 1.5 1.4e-06 28.4 1.5 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MGTL PF17059.5 AAAP01003880.1_88 - 0.45 10.4 1.7 1.4 8.9 1.7 1.8 1 0 0 1 1 1 0 MgtA leader peptide AP_endonuc_2 PF01261.24 AAAP01003880.1_89 - 8.7e-21 74.3 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 AAAP01003880.1_89 - 0.08 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus Epimerase_2 PF02350.19 AAAP01003880.1_90 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF282 PF03380.14 AAAP01003880.1_90 - 0.17 11.8 0.4 0.36 10.8 0.4 1.5 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 MBOAT PF03062.19 AAAP01003880.1_91 - 3.2e-30 105.7 4.3 9.7e-30 104.1 2.5 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AAAP01003880.1_91 - 1.7e-05 25.0 1.8 4.8e-05 23.5 1.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_93 - 4.3e-60 203.9 0.0 1.1e-52 179.6 0.0 2.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003880.1_93 - 4.6e-58 196.5 0.0 5.6e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAAP01003880.1_93 - 2.2e-24 85.9 0.0 3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAAP01003880.1_93 - 4.8e-13 49.4 0.0 7.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAAP01003880.1_93 - 6.5e-13 48.4 0.2 2.9e-07 29.9 0.0 2.6 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 AAAP01003880.1_93 - 4.6e-12 45.7 0.0 1.4e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AAAP01003880.1_93 - 2e-09 37.0 0.0 2.6e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AAAP01003880.1_93 - 2.4e-08 33.8 0.0 9.5e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 AAAP01003880.1_93 - 0.00051 19.6 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 AAAP01003880.1_93 - 0.0032 17.7 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 AAAP01003880.1_93 - 0.011 15.7 0.2 0.034 14.1 0.2 1.8 1 1 0 1 1 1 0 KR domain NAD_binding_7 PF13241.6 AAAP01003880.1_93 - 0.017 15.6 0.0 0.069 13.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Glyco_transf_4 PF13439.6 AAAP01003880.1_93 - 0.089 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 TrkA_N PF02254.18 AAAP01003880.1_93 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PfkB PF00294.24 AAAP01003880.1_94 - 6.4e-21 74.9 0.1 9.5e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AAAP01003880.1_94 - 6.3e-12 45.9 0.0 1.4e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF4357 PF14267.6 AAAP01003880.1_94 - 0.029 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) FAD_syn PF06574.12 AAAP01003880.1_94 - 0.14 12.1 0.2 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 FAD synthetase Epimerase PF01370.21 AAAP01003880.1_95 - 1.5e-36 126.0 0.0 2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_95 - 1.8e-25 90.1 0.0 3.8e-25 89.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003880.1_95 - 2.2e-22 79.4 0.0 2.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AAAP01003880.1_95 - 2.5e-14 53.6 0.0 3.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AAAP01003880.1_95 - 2.6e-13 50.1 0.0 2.3e-12 47.0 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 AAAP01003880.1_95 - 1.6e-12 47.1 0.0 2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003880.1_95 - 3.1e-08 33.1 0.0 1.9e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003880.1_95 - 0.00018 20.8 0.0 0.052 12.7 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AAAP01003880.1_95 - 0.088 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 AAAP01003880.1_95 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ZnuA PF01297.17 AAAP01003880.1_95 - 0.17 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic HAD PF12710.7 AAAP01003880.1_96 - 0.0052 17.2 0.9 0.014 15.8 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF630 PF04783.12 AAAP01003880.1_97 - 0.035 14.3 0.5 0.087 13.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF630) CHASE3 PF05227.13 AAAP01003880.1_97 - 0.1 12.5 2.1 0.18 11.7 0.4 2.0 2 0 0 2 2 2 0 CHASE3 domain Transketolase_N PF00456.21 AAAP01003880.1_98 - 1.7e-48 165.3 0.0 2.8e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AAAP01003880.1_98 - 1e-10 41.3 0.0 1.3e-08 34.4 0.0 2.2 2 1 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AAAP01003880.1_98 - 7e-09 35.1 0.0 9.4e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AAAP01003880.1_98 - 1.7e-05 24.6 0.5 0.00049 19.9 0.5 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 AAAP01003880.1_98 - 0.00076 18.4 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain Transket_pyr PF02779.24 AAAP01003880.1_99 - 3.8e-27 95.1 0.1 6.6e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AAAP01003880.1_99 - 2.7e-24 85.4 0.0 5.1e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 AAAP01003880.1_99 - 0.0021 18.4 0.1 0.0074 16.6 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Epimerase PF01370.21 AAAP01003880.1_100 - 1e-34 120.1 0.0 1.3e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_100 - 2.9e-23 82.8 0.0 6.6e-21 75.0 0.0 2.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AAAP01003880.1_100 - 4.8e-16 58.7 0.0 6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01003880.1_100 - 9.1e-16 57.7 0.0 1.9e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01003880.1_100 - 3.1e-12 46.2 0.0 3.1e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 AAAP01003880.1_100 - 3e-10 39.7 0.0 2.7e-08 33.3 0.0 2.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AAAP01003880.1_100 - 3.8e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding E1_dh PF00676.20 AAAP01003880.1_101 - 4.4e-27 94.8 0.0 5.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AAAP01003880.1_101 - 4.9e-06 26.0 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AAAP01003880.1_101 - 1.1e-05 25.3 1.2 0.00017 21.4 0.2 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 AAAP01003880.1_101 - 0.093 11.7 0.0 0.18 10.8 0.0 1.5 1 1 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AAAP01003880.1_102 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain GDP_Man_Dehyd PF16363.5 AAAP01003880.1_103 - 1.4e-66 225.2 0.0 1.7e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003880.1_103 - 1.3e-45 155.8 0.0 1.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003880.1_103 - 3.6e-07 29.6 0.0 5.6e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003880.1_103 - 1.5e-06 27.5 0.0 3.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAAP01003880.1_103 - 2.6e-05 23.4 0.0 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01003880.1_103 - 3.6e-05 23.1 0.0 0.0011 18.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein dTDP_sugar_isom PF00908.17 AAAP01003880.1_104 - 6e-11 42.3 0.0 7.8e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase FdtA PF05523.11 AAAP01003880.1_104 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 WxcM-like, C-terminal PNK3P PF08645.11 AAAP01003880.1_105 - 1.6e-08 34.4 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 AAAP01003880.1_105 - 4.2e-08 33.1 0.0 7.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AAAP01003880.1_105 - 1.1e-07 32.2 0.0 5.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AAAP01003880.1_105 - 2.8e-06 27.8 0.0 4.8e-05 23.7 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NTP_transferase PF00483.23 AAAP01003880.1_105 - 0.00017 21.3 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hydrolase_6 PF13344.6 AAAP01003880.1_105 - 0.00087 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AAAP01003880.1_105 - 0.0019 18.6 0.1 0.0039 17.6 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NTP_transf_3 PF12804.7 AAAP01003880.1_105 - 0.043 14.2 1.1 0.3 11.4 0.6 2.4 2 1 0 2 2 2 0 MobA-like NTP transferase domain GHMP_kinases_N PF00288.26 AAAP01003880.1_106 - 7.3e-09 35.7 0.5 1.7e-08 34.6 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AAAP01003880.1_106 - 5.7e-08 33.0 0.2 2.2e-07 31.1 0.2 2.1 1 1 0 1 1 1 1 GHMP kinases C terminal Epimerase PF01370.21 AAAP01003880.1_107 - 5.5e-35 121.0 0.0 6.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_107 - 1.2e-34 120.2 0.0 1e-33 117.2 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AAAP01003880.1_107 - 2.8e-11 43.7 0.2 4.2e-11 43.1 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AAAP01003880.1_107 - 3.7e-10 40.0 0.3 6.2e-09 36.0 0.3 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 AAAP01003880.1_107 - 5.5e-10 38.8 0.0 8.8e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003880.1_107 - 9.3e-09 34.8 0.0 2.1e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AAAP01003880.1_107 - 9.1e-08 31.4 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AAAP01003880.1_107 - 3.8e-07 29.5 0.7 6.5e-05 22.2 0.7 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 AAAP01003880.1_107 - 6.4e-06 25.9 0.0 8.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AAAP01003880.1_107 - 3.7e-05 23.3 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 AAAP01003880.1_107 - 0.0015 18.2 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glyco_transf_4 PF13439.6 AAAP01003880.1_107 - 0.0022 18.0 0.2 0.0046 17.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AAAP01003880.1_107 - 0.021 15.3 6.3 0.071 13.5 6.4 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Sacchrp_dh_NADP PF03435.18 AAAP01003880.1_107 - 0.022 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 AAAP01003880.1_107 - 0.046 13.3 0.2 0.089 12.3 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_14 PF08484.11 AAAP01003880.1_108 - 1.8e-56 190.3 0.0 4.4e-56 189.1 0.0 1.6 2 0 0 2 2 2 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 AAAP01003880.1_108 - 1.5e-18 66.8 0.3 2.7e-18 66.0 0.3 1.4 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 AAAP01003880.1_108 - 1.1e-14 54.6 0.0 2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003880.1_108 - 2.2e-10 41.0 0.0 5.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_108 - 1.2e-07 32.4 0.0 2.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AAAP01003880.1_108 - 1.7e-07 31.8 0.1 8.1e-07 29.7 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003880.1_108 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain NBD_C PF17042.5 AAAP01003880.1_108 - 0.015 15.8 0.2 0.034 14.7 0.2 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DOT1 PF08123.13 AAAP01003880.1_108 - 0.016 14.8 0.0 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 CMAS PF02353.20 AAAP01003880.1_108 - 0.19 11.0 0.0 0.7 9.1 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase dTDP_sugar_isom PF00908.17 AAAP01003880.1_109 - 4.9e-44 150.0 0.0 5.5e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Methyltransf_25 PF13649.6 AAAP01003880.1_110 - 2.9e-19 69.5 0.0 4.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003880.1_110 - 5.6e-16 59.0 0.0 8.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003880.1_110 - 2.1e-13 50.3 0.0 2.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_110 - 3.4e-13 50.2 0.0 5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003880.1_110 - 8.3e-13 48.5 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AAAP01003880.1_110 - 6.2e-07 29.0 0.0 9.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAAP01003880.1_110 - 0.00024 20.5 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAAP01003880.1_110 - 0.00071 19.2 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AAAP01003880.1_110 - 0.0063 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 AAAP01003880.1_110 - 0.0077 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 AAAP01003880.1_110 - 0.068 12.1 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Glycos_transf_2 PF00535.26 AAAP01003880.1_111 - 2.3e-29 102.4 0.1 3e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_111 - 0.00068 19.6 0.0 0.0009 19.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AAAP01003880.1_111 - 0.041 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 AAAP01003880.1_111 - 0.19 12.1 0.0 0.52 10.7 0.0 1.6 1 1 0 2 2 2 0 MobA-like NTP transferase domain AMP-binding PF00501.28 AAAP01003880.1_112 - 1.2e-06 27.4 0.5 3.9e-06 25.7 0.0 2.0 3 0 0 3 3 3 1 AMP-binding enzyme Epimerase_2 PF02350.19 AAAP01003880.1_113 - 5e-84 282.1 0.0 5.7e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase LSDAT_prok PF18171.1 AAAP01003880.1_113 - 0.028 13.7 0.1 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote DRTGG PF07085.12 AAAP01003880.1_113 - 0.098 12.5 0.4 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 DRTGG domain DUF4417 PF14386.6 AAAP01003880.1_113 - 0.21 11.2 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) NeuB PF03102.14 AAAP01003880.1_114 - 2.9e-84 282.3 0.0 3.4e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 AAAP01003880.1_114 - 2.1e-11 44.3 0.1 1.8e-10 41.3 0.0 2.5 3 0 0 3 3 3 1 SAF domain Acetyltransf_6 PF13480.7 AAAP01003880.1_115 - 1.9e-12 47.5 5.8 1.2e-11 45.0 2.7 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 AAAP01003880.1_115 - 3.8e-08 32.6 0.0 0.00011 21.2 0.0 3.0 1 1 1 3 3 3 2 FemAB family Mig-14 PF07395.11 AAAP01003880.1_115 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Mig-14 CTP_transf_3 PF02348.19 AAAP01003880.1_116 - 2.3e-24 86.5 0.0 2.8e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01003880.1_116 - 9.4e-07 29.3 1.4 1.3e-06 28.9 1.4 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AAAP01003880.1_116 - 0.0022 17.8 0.1 0.0033 17.2 0.1 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Methyltransf_23 PF13489.6 AAAP01003880.1_117 - 9.2e-13 48.3 0.0 1.3e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003880.1_117 - 0.012 16.3 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_117 - 0.044 14.5 0.0 0.17 12.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 AAAP01003880.1_118 - 6.4e-54 183.0 1.5 7.3e-54 182.8 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AAAP01003880.1_118 - 1e-49 168.6 0.1 1.4e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AAAP01003880.1_118 - 6.2e-10 39.3 0.3 9.8e-10 38.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AAAP01003880.1_118 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AAAP01003880.1_118 - 0.066 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 AAAP01003880.1_118 - 0.095 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Radical_SAM PF04055.21 AAAP01003880.1_120 - 2.9e-17 63.6 0.1 7e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AAAP01003880.1_120 - 1.7e-11 44.2 0.0 3.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 AAAP01003880.1_121 - 3.3e-12 47.1 0.2 5.9e-12 46.3 0.1 1.5 2 0 0 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 AAAP01003880.1_121 - 2.3e-05 24.8 0.0 5.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AAAP01003880.1_121 - 0.0072 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain IlvC PF01450.19 AAAP01003880.1_121 - 0.16 12.2 0.1 0.25 11.6 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.22 AAAP01003880.1_122 - 5.4e-26 91.8 0.0 8.5e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 AAAP01003880.1_122 - 0.00031 21.4 0.0 0.0006 20.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AAAP01003880.1_122 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 AAAP01003880.1_122 - 0.0019 18.3 0.0 0.0046 17.1 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 AAAP01003880.1_122 - 0.012 16.1 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 AAAP01003880.1_122 - 0.15 12.4 0.0 0.72 10.2 0.0 2.1 1 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Epimerase PF01370.21 AAAP01003880.1_123 - 1.9e-50 171.6 0.0 2.2e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_123 - 1.4e-47 162.7 0.0 4.5e-47 161.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003880.1_123 - 5.3e-23 81.4 0.0 6.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01003880.1_123 - 1.3e-11 44.2 0.0 4.1e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AAAP01003880.1_123 - 4.7e-08 33.1 0.1 7.3e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AAAP01003880.1_123 - 1.5e-07 31.1 0.3 6.4e-07 29.0 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AAAP01003880.1_123 - 1.1e-06 28.0 0.0 9.2e-05 21.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 AAAP01003880.1_123 - 1.6e-06 27.9 0.1 8.3e-06 25.5 0.1 2.0 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 AAAP01003880.1_123 - 2.2e-05 23.7 0.0 3.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 AAAP01003880.1_123 - 0.00043 20.2 0.6 0.0012 18.8 0.6 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 AAAP01003880.1_123 - 0.0012 18.5 0.3 0.0064 16.1 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M55 PF04951.13 AAAP01003880.1_123 - 0.026 13.9 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 D-aminopeptidase ThiF PF00899.21 AAAP01003880.1_123 - 0.14 11.5 0.3 0.39 10.0 0.4 1.7 2 0 0 2 2 2 0 ThiF family Epimerase PF01370.21 AAAP01003880.1_125 - 5.5e-07 29.3 0.0 6.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_125 - 0.00083 18.8 0.0 0.0088 15.5 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AAAP01003880.1_125 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 AAAP01003880.1_125 - 0.013 14.6 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 AAAP01003880.1_125 - 0.015 14.3 0.1 0.021 13.8 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_trans_4_4 PF13579.6 AAAP01003880.1_125 - 0.018 15.5 3.3 0.023 15.1 3.3 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain adh_short PF00106.25 AAAP01003880.1_125 - 0.022 14.2 0.0 0.032 13.7 0.0 1.4 2 0 0 2 2 2 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 AAAP01003880.1_125 - 0.049 12.9 0.2 0.51 9.6 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 AAAP01003880.1_125 - 0.067 13.1 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 AAAP01003880.1_125 - 0.19 10.9 0.1 1.4 8.1 0.4 1.8 2 0 0 2 2 2 0 Male sterility protein Glycos_transf_2 PF00535.26 AAAP01003880.1_127 - 4.5e-27 94.9 0.0 6.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_127 - 4.7e-07 29.9 0.0 7.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 AAAP01003880.1_127 - 0.00026 21.4 0.1 0.00037 20.9 0.1 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain MFS_1 PF07690.16 AAAP01003880.1_127 - 0.0013 17.7 3.7 0.0022 17.0 3.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PPR_1 PF12854.7 AAAP01003880.1_127 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 PPR repeat DUF2975 PF11188.8 AAAP01003880.1_127 - 0.28 11.1 3.7 0.21 11.5 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) FAA_hydrolase PF01557.18 AAAP01003880.1_128 - 0.09 12.4 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family GLF PF03275.13 AAAP01003880.1_129 - 7.9e-32 110.6 0.9 7.9e-32 110.6 0.9 1.6 2 0 0 2 2 2 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 AAAP01003880.1_129 - 1.3e-10 41.4 0.2 2.8e-10 40.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AAAP01003880.1_129 - 9e-07 28.8 2.0 4.8e-06 26.4 2.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AAAP01003880.1_129 - 5.2e-06 26.0 0.0 2.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AAAP01003880.1_129 - 0.00021 20.5 0.3 0.0003 20.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AAAP01003880.1_129 - 0.00054 19.3 0.2 0.0013 18.0 0.2 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AAAP01003880.1_129 - 0.0065 17.0 0.1 0.015 15.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 AAAP01003880.1_129 - 0.011 14.7 0.3 0.21 10.4 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 AAAP01003880.1_129 - 0.066 12.4 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 AAAP01003880.1_129 - 0.073 12.3 1.3 0.14 11.4 1.3 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 AAAP01003880.1_129 - 0.073 12.4 3.3 0.052 12.9 1.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 AAAP01003880.1_129 - 0.35 9.9 0.6 0.49 9.4 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Radical_SAM PF04055.21 AAAP01003880.1_130 - 3.4e-14 53.6 0.1 2.5e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 AAAP01003880.1_130 - 4.2e-09 36.8 0.4 1.1e-08 35.4 0.4 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 AAAP01003880.1_130 - 6.5e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AAAP01003880.1_130 - 9.3e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain zf-IS66 PF13005.7 AAAP01003880.1_130 - 0.02 15.3 0.4 0.068 13.6 0.4 1.9 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 Toprim_3 PF13362.6 AAAP01003880.1_130 - 0.14 12.5 0.2 3 8.3 0.2 2.5 1 1 0 1 1 1 0 Toprim domain Lipase_GDSL_2 PF13472.6 AAAP01003880.1_131 - 1e-08 35.8 2.5 5.5e-07 30.2 2.5 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF433 PF04255.14 AAAP01003880.1_131 - 0.016 15.0 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF433) zf-HC2 PF13490.6 AAAP01003880.1_133 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative zinc-finger Aminotran_3 PF00202.21 AAAP01003880.1_134 - 1.3e-73 248.0 0.0 1.6e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AAAP01003880.1_134 - 0.00022 20.5 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Imm40 PF15569.6 AAAP01003880.1_134 - 0.071 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 40 Epimerase PF01370.21 AAAP01003880.1_135 - 1.7e-51 175.0 0.0 2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_135 - 6.6e-50 170.4 0.0 1.1e-42 146.6 0.0 2.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AAAP01003880.1_135 - 3.2e-17 62.5 0.0 4.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01003880.1_135 - 3.2e-14 52.8 0.4 6.6e-13 48.4 0.4 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AAAP01003880.1_135 - 1.6e-12 47.1 2.6 4.6e-08 32.5 0.1 2.8 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003880.1_135 - 1.8e-11 43.7 0.0 2.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AAAP01003880.1_135 - 1.3e-09 38.2 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AAAP01003880.1_135 - 0.00013 21.5 0.4 0.0023 17.4 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 AAAP01003880.1_135 - 0.017 14.7 0.1 0.035 13.7 0.1 1.6 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 AAAP01003880.1_135 - 0.041 13.8 0.5 0.72 9.7 0.2 2.3 2 0 0 2 2 2 0 KR domain Acetyltransf_3 PF13302.7 AAAP01003880.1_136 - 1.1e-29 103.8 0.0 1.4e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AAAP01003880.1_136 - 5e-08 33.2 0.0 6.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AAAP01003880.1_136 - 0.0013 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PsbM PF05151.12 AAAP01003880.1_137 - 0.062 13.1 0.3 0.062 13.1 0.3 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) Methyltransf_25 PF13649.6 AAAP01003880.1_138 - 1.4e-19 70.6 0.0 2.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAAP01003880.1_138 - 1.6e-16 60.7 0.0 2.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AAAP01003880.1_138 - 3.8e-14 52.7 0.0 5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AAAP01003880.1_138 - 1.7e-13 50.7 0.0 2.2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AAAP01003880.1_138 - 2.2e-13 50.8 0.0 3.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AAAP01003880.1_138 - 1.1e-05 24.5 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 AAAP01003880.1_138 - 1.8e-05 24.2 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 AAAP01003880.1_138 - 2e-05 24.1 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 AAAP01003880.1_138 - 0.00028 20.5 0.0 0.00084 19.0 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 AAAP01003880.1_138 - 0.002 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AAAP01003880.1_138 - 0.0077 15.9 0.0 0.0092 15.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Pox_MCEL PF03291.16 AAAP01003880.1_138 - 0.011 14.9 0.0 0.78 8.8 0.0 2.0 1 1 0 1 1 1 0 mRNA capping enzyme CheR PF01739.18 AAAP01003880.1_138 - 0.027 14.0 0.0 0.061 12.8 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 AAAP01003880.1_138 - 0.1 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 AAAP01003880.1_138 - 0.17 11.7 0.0 2.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 AAAP01003880.1_138 - 0.17 11.2 0.0 0.25 10.6 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain CTP_transf_3 PF02348.19 AAAP01003880.1_139 - 3.8e-33 115.3 0.0 4.8e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AAAP01003880.1_139 - 3.9e-08 33.8 0.0 6.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain PK_C PF02887.16 AAAP01003880.1_139 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain B12-binding PF02310.19 AAAP01003880.1_140 - 4e-10 39.8 0.0 9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 AAAP01003880.1_140 - 2.3e-07 31.3 0.0 7e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily ADH_N PF08240.12 AAAP01003880.1_141 - 1.4e-27 95.8 1.5 2.3e-27 95.0 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glycos_transf_2 PF00535.26 AAAP01003880.1_141 - 6e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glu_dehyd_C PF16912.5 AAAP01003880.1_141 - 1.6e-13 50.6 0.0 2.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_141 - 2.4e-12 47.3 0.1 9.4e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 ADH_zinc_N PF00107.26 AAAP01003880.1_141 - 2.7e-08 33.9 0.0 9.3e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 AAAP01003880.1_141 - 0.00024 21.0 0.0 0.00068 19.6 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AAAP01003880.1_141 - 0.00036 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 AAAP01003880.1_141 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 AAAP01003880.1_141 - 0.0033 18.5 0.0 0.011 16.8 0.0 1.9 2 0 0 2 2 1 1 Zinc-binding dehydrogenase DAO PF01266.24 AAAP01003880.1_141 - 0.0054 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AAAP01003880.1_141 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AAAP01003880.1_141 - 0.017 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 AAAP01003880.1_141 - 0.018 15.2 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HU-DNA_bdg PF14848.6 AAAP01003880.1_141 - 0.035 14.1 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA-binding domain adh_short PF00106.25 AAAP01003880.1_141 - 0.06 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase DUF531 PF04407.12 AAAP01003880.1_141 - 0.11 12.5 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF531) HI0933_like PF03486.14 AAAP01003880.1_141 - 0.2 10.3 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 AAAP01003880.1_142 - 1.1e-54 184.5 0.0 3.8e-54 182.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AAAP01003880.1_142 - 7.5e-17 61.2 0.0 8.5e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 AAAP01003880.1_142 - 0.038 13.3 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 AAAP01003880.1_142 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cyclase PF04199.13 AAAP01003880.1_143 - 4.4e-21 75.5 0.0 6.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Epimerase PF01370.21 AAAP01003880.1_144 - 4.6e-49 167.1 0.0 5.5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AAAP01003880.1_144 - 3.4e-42 145.0 0.0 4.6e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 AAAP01003880.1_144 - 1.3e-09 38.0 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 AAAP01003880.1_144 - 2.6e-09 36.5 0.0 1.2e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AAAP01003880.1_144 - 9.5e-09 34.8 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AAAP01003880.1_144 - 4.9e-08 32.5 0.0 1.8e-06 27.3 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AAAP01003880.1_144 - 1.2e-05 25.3 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 AAAP01003880.1_144 - 0.012 15.0 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase TrkA_N PF02254.18 AAAP01003880.1_144 - 0.035 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 AAAP01003880.1_144 - 0.045 13.7 0.2 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 KR domain ApbA PF02558.16 AAAP01003880.1_144 - 0.16 11.6 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NTP_transferase PF00483.23 AAAP01003880.1_145 - 1.1e-36 126.7 0.0 1.5e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase CBS PF00571.28 AAAP01003880.1_145 - 3.6e-11 43.4 0.8 0.00017 21.9 0.6 2.6 2 0 0 2 2 2 2 CBS domain NTP_transf_3 PF12804.7 AAAP01003880.1_145 - 1.6e-10 41.6 0.5 4.2e-10 40.2 0.1 1.9 3 0 0 3 3 3 1 MobA-like NTP transferase domain DegT_DnrJ_EryC1 PF01041.17 AAAP01003880.1_147 - 3.5e-87 293.1 0.0 4.3e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AAAP01003880.1_147 - 2.1e-05 24.0 0.1 3.5e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AAAP01003880.1_147 - 2.8e-05 23.5 0.0 3.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AAAP01003880.1_147 - 0.004 15.8 0.1 0.006 15.2 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GDP_Man_Dehyd PF16363.5 AAAP01003880.1_148 - 9.4e-70 235.6 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AAAP01003880.1_148 - 1.2e-55 188.7 0.0 1.4e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AAAP01003880.1_148 - 5.4e-25 87.9 0.0 7.1e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AAAP01003880.1_148 - 4.9e-17 62.0 0.0 8.7e-16 57.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AAAP01003880.1_148 - 3.3e-14 53.2 0.0 2.2e-13 50.5 0.0 2.2 1 1 1 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AAAP01003880.1_148 - 3.9e-13 49.2 0.0 3.8e-11 42.6 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 AAAP01003880.1_148 - 4.8e-12 45.6 0.0 6.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AAAP01003880.1_148 - 4.3e-08 32.8 0.0 1.1e-06 28.3 0.0 3.0 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 AAAP01003880.1_148 - 4.6e-05 23.1 0.0 0.00017 21.2 0.0 1.9 2 1 0 2 2 2 1 NmrA-like family HTH_8 PF02954.19 AAAP01003880.1_148 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family PMT_2 PF13231.6 AAAP01003880.1_149 - 3.1e-10 40.5 20.0 1.3e-09 38.5 10.7 2.5 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Glycos_transf_2 PF00535.26 AAAP01003880.1_151 - 3.8e-13 49.6 0.2 5.6e-13 49.0 0.2 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AAAP01003880.1_151 - 0.0033 17.3 0.0 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AAAP01003880.1_151 - 0.048 14.2 0.1 0.29 11.7 0.0 2.2 3 0 0 3 3 3 0 Glycosyl transferase family 2 Hexapep PF00132.24 AAAP01003880.1_152 - 1.6e-22 78.3 13.4 4.2e-08 32.6 0.3 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AAAP01003880.1_152 - 3.7e-14 52.2 12.9 1.1e-05 25.1 1.4 4.2 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase GFO_IDH_MocA PF01408.22 AAAP01003880.1_153 - 3.3e-26 92.5 0.0 5.5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AAAP01003880.1_153 - 1.4e-05 25.1 0.0 0.00013 22.0 0.0 2.6 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 AAAP01003880.1_153 - 0.024 15.2 0.0 0.077 13.6 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_deac_2 PF04748.13 AAAP01003880.1_153 - 0.033 13.4 0.1 1.8 7.7 0.0 2.3 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase NAD_binding_3 PF03447.16 AAAP01003880.1_153 - 0.12 13.1 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DegT_DnrJ_EryC1 PF01041.17 AAAP01003880.1_154 - 2.3e-118 395.7 0.0 2.6e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AAAP01003880.1_154 - 4.5e-13 49.1 0.0 6.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AAAP01003880.1_154 - 1.1e-08 34.5 0.0 2.6e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AAAP01003880.1_154 - 6.3e-06 25.7 0.4 2.5e-05 23.7 0.4 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AAAP01003880.1_154 - 0.0084 14.7 0.1 0.012 14.2 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 AAAP01003880.1_154 - 0.065 12.0 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Magnetospirillum_magnetotacticum-MS-1-ASM16687v1/Prodigal-protein.translations.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Magnetospirillum_magnetotacticum-MS-1-ASM16687v1/Prodigal-protein.translations.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Magnetospirillum_magnetotacticum-MS-1-ASM16687v1/Prodigal-protein.translations.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Magnetospirillum_magnetotacticum-MS-1-ASM16687v1/Prodigal-protein.translations.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:58:20 2019 # [ok]