# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DDE_3 PF13358.6 ETZ04335.1 - 9.3e-07 28.7 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TIG_plexin PF17960.1 ETZ04335.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 TIG domain Exonuc_VII_L PF02601.15 ETZ04336.1 - 1.2e-35 123.5 0.0 1.5e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 ETZ04337.1 - 1.7e-26 92.2 0.4 2.6e-26 91.7 0.4 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Exonuc_VII_L PF02601.15 ETZ04337.1 - 1.3e-20 74.2 0.0 2.3e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti-codon PF01336.25 ETZ04337.1 - 5.6e-06 26.3 0.2 9.9e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ROF PF07073.12 ETZ04337.1 - 0.037 14.2 0.2 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) DUF2608 PF11019.8 ETZ04341.1 - 3.3e-31 108.7 0.0 3.9e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) PGP_phosphatase PF09419.10 ETZ04341.1 - 0.062 12.9 0.0 4.1 7.0 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial PGP phosphatase NUDIX PF00293.28 ETZ04342.1 - 2.3e-12 47.1 0.1 2.6e-12 46.9 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ETZ04342.1 - 9.5e-07 28.8 0.1 2.1e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain Acetyltransf_10 PF13673.7 ETZ04343.1 - 7e-10 38.9 0.1 9.5e-10 38.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04343.1 - 5.2e-08 33.1 0.0 6.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04343.1 - 1.3e-07 32.0 0.1 1.8e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETZ04343.1 - 5.7e-05 23.3 0.2 6.8e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETZ04343.1 - 0.029 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 ETZ04344.1 - 6.3e-06 26.4 0.0 6.8e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04344.1 - 0.0037 17.7 0.0 0.0048 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PBECR2 PF18810.1 ETZ04344.1 - 0.041 14.2 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Acetyltransf_10 PF13673.7 ETZ04344.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EcKinase PF02958.20 ETZ04347.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_1 PF00561.20 ETZ04348.1 - 3.8e-23 82.5 0.0 3.4e-21 76.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETZ04348.1 - 4.5e-12 47.0 0.0 5.6e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ETZ04348.1 - 3.9e-06 26.6 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ETZ04348.1 - 1.3e-05 24.5 0.0 4.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ETZ04348.1 - 0.00054 18.7 0.0 0.0008 18.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 ETZ04348.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain MFS_1 PF07690.16 ETZ04349.1 - 8.1e-43 146.7 39.1 1.2e-42 146.2 39.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETZ04349.1 - 1.7e-08 33.8 15.2 1.7e-08 33.8 15.2 3.1 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ETZ04349.1 - 1.7e-06 26.8 2.5 1.7e-06 26.8 2.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Zn_ribbon_recom PF13408.6 ETZ04351.1 - 1.3e-12 48.0 2.6 2.4e-12 47.1 2.6 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 ETZ04351.1 - 5.8e-08 33.1 0.0 2.2e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Recombinase Ogr_Delta PF04606.12 ETZ04351.1 - 1.3 9.0 6.2 1 9.4 3.1 2.5 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Resolvase PF00239.21 ETZ04352.1 - 1.1e-35 122.9 0.1 1.3e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain MinC_N PF05209.13 ETZ04352.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DUF2924 PF11149.8 ETZ04353.1 - 5.2e-46 156.4 0.0 6e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2924) RAMA PF18755.1 ETZ04353.1 - 0.00029 21.2 0.0 0.00045 20.6 0.0 1.4 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated DUF4054 PF13262.6 ETZ04354.1 - 0.034 14.2 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) LexA_DNA_bind PF01726.16 ETZ04355.1 - 6.8e-11 41.8 0.1 1.1e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 ETZ04355.1 - 1.4e-09 37.8 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Fe_dep_repress PF01325.19 ETZ04355.1 - 0.004 17.3 0.0 0.0063 16.7 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 ETZ04355.1 - 0.0057 16.3 0.3 0.01 15.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 ETZ04355.1 - 0.0069 16.2 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ETZ04355.1 - 0.057 13.8 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator AAA_25 PF13481.6 ETZ04358.1 - 4e-21 75.5 0.0 1.1e-20 74.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain Toprim_4 PF13662.6 ETZ04358.1 - 0.00013 22.3 0.0 0.00034 21.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 ETZ04358.1 - 0.00086 19.7 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 ETZ04358.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Toprim domain PDDEXK_1 PF12705.7 ETZ04359.1 - 0.00033 20.7 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily YqaJ PF09588.10 ETZ04359.1 - 0.00038 20.6 0.0 0.00088 19.4 0.0 1.6 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain LAGLIDADG_3 PF14528.6 ETZ04362.1 - 1e-08 35.4 0.0 9.4e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 LAGLIDADG-like domain Hom_end PF05204.14 ETZ04362.1 - 2e-06 27.9 0.0 1.7e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Homing endonuclease Hom_end_hint PF05203.16 ETZ04363.1 - 4.7e-09 36.5 0.0 5.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint AAA_24 PF13479.6 ETZ04365.1 - 6.4e-38 130.5 0.0 7.7e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain Phage_Mu_Gam PF07352.12 ETZ04366.1 - 0.011 15.7 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Ribonuc_red_lgC PF02867.15 ETZ04366.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Sigma70_r2 PF04542.14 ETZ04367.1 - 0.00014 21.5 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 ETZ04367.1 - 0.0011 18.9 0.3 0.0029 17.5 0.3 1.7 1 1 0 1 1 1 1 ECF sigma factor HTH_11 PF08279.12 ETZ04367.1 - 0.035 14.1 0.1 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 HTH domain TrmB PF01978.19 ETZ04367.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ParBc PF02195.18 ETZ04369.1 - 4.7e-12 46.0 0.0 1.5e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain UBA_4 PF14555.6 ETZ04369.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain N6_N4_Mtase PF01555.18 ETZ04370.1 - 1.4e-23 83.9 0.0 2.6e-22 79.7 0.0 2.0 1 1 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 ETZ04370.1 - 0.00043 20.0 0.0 0.00054 19.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 ETZ04370.1 - 0.033 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 ETZ04370.1 - 0.055 13.2 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Terminase_GpA PF05876.12 ETZ04372.1 - 3.5e-148 494.6 0.0 4.2e-148 494.4 0.0 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) TFIIS_C PF01096.18 ETZ04372.1 - 0.041 13.7 0.2 0.082 12.8 0.2 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Terminase_GpA PF05876.12 ETZ04373.1 - 1e-32 113.5 0.6 1.1e-32 113.4 0.6 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Terminase_GpA PF05876.12 ETZ04374.1 - 1.6e-35 122.8 0.0 1.7e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) DUF2183 PF09949.9 ETZ04374.1 - 0.086 13.2 0.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) gpW PF02831.15 ETZ04375.1 - 1.1e-06 28.4 0.1 1.3e-06 28.2 0.1 1.3 1 1 0 1 1 1 1 gpW AAA_lid_7 PF17867.1 ETZ04375.1 - 0.033 14.4 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 Midasin AAA lid domain Phage_portal_2 PF05136.13 ETZ04377.1 - 1.3e-104 350.3 0.0 1.7e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein, lambda family Peptidase_S49 PF01343.18 ETZ04378.1 - 1.7e-31 109.2 0.1 3.1e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 ETZ04378.1 - 8.5e-05 22.5 1.2 0.0005 20.0 0.2 2.5 3 0 0 3 3 3 1 Clp protease HDPD PF02924.14 ETZ04379.1 - 9.6e-19 67.6 0.2 1e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 Bacteriophage lambda head decoration protein D Phage_cap_E PF03864.15 ETZ04380.1 - 7.9e-114 380.3 0.0 8.8e-114 380.1 0.0 1.0 1 0 0 1 1 1 1 Phage major capsid protein E Minor_tail_Z PF06763.11 ETZ04382.1 - 1.6e-13 50.9 3.8 6e-13 49.0 3.8 1.8 1 1 0 1 1 1 1 Prophage minor tail protein Z (GPZ) Phage_base_V PF04717.12 ETZ04384.1 - 1e-42 144.6 0.0 1.1e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector DUF4121 PF13497.6 ETZ04384.1 - 0.013 14.6 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Phage_Mu_Gp45 PF06890.12 ETZ04384.1 - 0.11 12.2 0.2 0.68 9.7 0.2 2.0 1 1 0 1 1 1 0 Bacteriophage Mu Gp45 protein PAAR_motif PF05488.13 ETZ04385.1 - 1e-12 48.1 2.9 7.1e-12 45.3 1.1 2.0 1 1 1 2 2 2 2 PAAR motif DUF4150 PF13665.6 ETZ04385.1 - 0.053 13.7 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) GPW_gp25 PF04965.14 ETZ04386.1 - 2.5e-14 52.8 0.0 3.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme DUF2634 PF10934.8 ETZ04386.1 - 0.00054 20.0 0.0 0.00071 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) Baseplate_J PF04865.14 ETZ04388.1 - 4.4e-20 71.9 0.0 5.7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Baseplate J-like protein Tail_P2_I PF09684.10 ETZ04389.1 - 2.2e-08 34.1 0.0 5.3e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Phage tail protein (Tail_P2_I) DUF2460 PF09343.10 ETZ04390.1 - 0.13 11.7 0.4 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 2217 (DUF2460) DUF4815 PF16075.5 ETZ04391.1 - 3.8e-189 629.7 0.0 4.8e-189 629.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4815) DBB PF14545.6 ETZ04391.1 - 0.041 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, PT-VENN PF04829.13 ETZ04391.1 - 0.1 12.7 0.4 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4082 PF13313.6 ETZ04392.1 - 0.043 13.9 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Glycohydro_20b2 PF14845.6 ETZ04393.1 - 0.075 13.7 0.0 0.086 13.5 0.0 1.0 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like Phage_sheath_1 PF04984.14 ETZ04397.1 - 5e-18 65.5 0.0 7.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 ETZ04398.1 - 1.2e-08 34.8 0.0 1.4e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain Phage_tube PF04985.14 ETZ04399.1 - 1.5e-47 161.3 0.0 2.1e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Phage tail tube protein FII MPC PF03650.13 ETZ04400.1 - 0.065 13.4 0.3 0.11 12.7 0.2 1.4 1 1 1 2 2 2 0 Mitochondrial pyruvate carriers Glycos_transf_1 PF00534.20 ETZ04402.1 - 3.9e-37 127.4 0.0 4.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ04402.1 - 8.8e-30 103.9 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ETZ04402.1 - 0.0013 19.1 0.0 0.0032 17.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 ROQ_II PF18386.1 ETZ04402.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Roquin II domain Glyco_transf_4 PF13439.6 ETZ04404.1 - 5.9e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ETZ04404.1 - 1.2e-06 28.2 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETZ04404.1 - 5e-06 27.0 0.0 7.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Asn_synthase PF00733.21 ETZ04405.1 - 3.2e-90 303.4 0.0 4.1e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ETZ04405.1 - 2.4e-40 137.2 0.0 4e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETZ04405.1 - 1.6e-32 112.5 0.0 2.6e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 ETZ04405.1 - 0.00075 18.7 0.0 0.002 17.3 0.0 1.7 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 ETZ04405.1 - 0.0037 16.8 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF3700 PF12481.8 ETZ04405.1 - 0.088 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein Methyltransf_11 PF08241.12 ETZ04406.1 - 4.9e-25 88.0 0.0 8.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04406.1 - 7.7e-24 84.2 0.0 1.4e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04406.1 - 1.1e-18 67.5 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04406.1 - 2.8e-18 66.3 0.0 4.6e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ04406.1 - 1.9e-17 63.8 0.0 4.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04406.1 - 1e-10 41.4 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ETZ04406.1 - 4.6e-08 32.7 0.0 6.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ETZ04406.1 - 7.4e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ETZ04406.1 - 2e-05 24.1 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 ETZ04406.1 - 0.00024 20.8 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 ETZ04406.1 - 0.00068 18.7 0.0 0.00095 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 ETZ04406.1 - 0.0024 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 ETZ04406.1 - 0.0024 17.8 0.0 0.0041 17.0 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Pox_MCEL PF03291.16 ETZ04406.1 - 0.0029 16.8 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_4 PF02390.17 ETZ04406.1 - 0.0043 16.5 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 ETZ04406.1 - 0.0052 16.2 0.0 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 ETZ04406.1 - 0.18 11.5 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein DUF5494 PF17598.2 ETZ04407.1 - 0.031 14.4 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5494) Polysacc_deac_1 PF01522.21 ETZ04408.1 - 3.7e-05 23.6 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETZ04408.1 - 0.0022 17.7 1.2 0.0033 17.1 1.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) MBOAT PF03062.19 ETZ04410.1 - 6.6e-27 94.8 19.3 6.6e-27 94.8 19.3 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ETZ04410.1 - 4.5e-05 23.6 1.7 0.00022 21.4 1.7 2.3 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Epimerase_2 PF02350.19 ETZ04411.1 - 1.3e-100 336.7 0.0 1.5e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 ETZ04411.1 - 0.0051 15.9 0.2 0.0069 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Glycos_transf_1 PF00534.20 ETZ04412.1 - 1.6e-16 60.3 0.1 3.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ04412.1 - 3.5e-13 50.1 0.0 6.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ04412.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Epimerase_2 PF02350.19 ETZ04412.1 - 0.085 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 ETZ04412.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Methyltransf_11 PF08241.12 ETZ04413.1 - 2e-16 60.4 0.0 3.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04413.1 - 1.6e-14 54.1 0.0 2.2e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04413.1 - 1.7e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04413.1 - 1.4e-12 48.2 0.0 2.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04413.1 - 2.7e-09 36.7 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETZ04413.1 - 3e-07 31.1 0.0 9e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ETZ04413.1 - 1.4e-05 24.6 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ETZ04413.1 - 6e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETZ04413.1 - 0.0025 17.4 0.0 0.0087 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 ETZ04413.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 1 1 2 2 2 0 DREV methyltransferase Methyltransf_11 PF08241.12 ETZ04414.1 - 1.7e-20 73.4 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04414.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04414.1 - 7.2e-15 55.5 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04414.1 - 6.7e-13 48.7 0.0 1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ04414.1 - 3.2e-12 47.1 0.0 5.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04414.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ETZ04414.1 - 4e-06 26.3 0.0 9.7e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ETZ04414.1 - 4.2e-06 26.5 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 ETZ04414.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.15 ETZ04414.1 - 0.034 14.0 0.1 0.52 10.1 0.0 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ETZ04415.1 - 9.4e-23 80.7 0.0 2.1e-22 79.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04415.1 - 3.2e-20 72.6 0.0 6.6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04415.1 - 6.4e-20 71.5 0.3 1e-19 70.8 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04415.1 - 1.2e-14 54.3 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETZ04415.1 - 4.4e-13 49.8 0.0 1.6e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04415.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETZ04415.1 - 1.5e-08 34.4 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ETZ04415.1 - 3.2e-06 26.3 0.0 4.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ETZ04415.1 - 5.2e-06 26.1 0.0 6e-05 22.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ETZ04415.1 - 5.9e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 ETZ04415.1 - 6e-06 25.8 0.4 8.4e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 ETZ04415.1 - 2e-05 24.3 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 ETZ04415.1 - 0.001 18.6 0.1 0.0014 18.2 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 ETZ04415.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ETZ04415.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04415.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 ETZ04415.1 - 0.004 16.9 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_4 PF02390.17 ETZ04415.1 - 0.0045 16.5 0.1 0.019 14.4 0.1 1.9 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 ETZ04415.1 - 0.012 15.5 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 ETZ04415.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 ETZ04415.1 - 0.014 15.0 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 ETZ04415.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF43 PF01861.16 ETZ04415.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain FemAB PF02388.16 ETZ04416.1 - 4.9e-15 55.3 5.6 6.2e-08 31.9 0.8 2.8 2 1 1 3 3 3 2 FemAB family Acetyltransf_6 PF13480.7 ETZ04416.1 - 1.2e-11 44.9 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04416.1 - 0.085 13.1 0.2 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family ABC_tran PF00005.27 ETZ04417.1 - 4.3e-29 101.8 0.0 6.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ04417.1 - 3.3e-08 33.2 0.9 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 ETZ04417.1 - 6e-08 32.7 10.1 9.2e-08 32.1 10.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_ATPase PF09818.9 ETZ04417.1 - 0.00013 21.0 0.7 0.004 16.0 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DEAD PF00270.29 ETZ04417.1 - 0.00066 19.5 0.7 0.013 15.3 0.1 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETZ04417.1 - 0.0011 19.3 0.1 0.065 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETZ04417.1 - 0.0028 17.3 0.2 0.0061 16.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 ETZ04417.1 - 0.0031 17.7 0.8 0.0062 16.7 0.3 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 ETZ04417.1 - 0.0061 15.7 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ETZ04417.1 - 0.0079 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ04417.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ETZ04417.1 - 0.022 15.1 0.0 0.041 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ETZ04417.1 - 0.022 15.2 0.9 0.043 14.3 0.4 1.7 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.6 ETZ04417.1 - 0.023 14.9 0.4 0.11 12.7 0.4 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ETZ04417.1 - 0.033 14.6 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 ETZ04417.1 - 0.073 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Dynamin family AAA PF00004.29 ETZ04417.1 - 0.091 13.2 0.4 2.9 8.3 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 ETZ04417.1 - 0.093 12.5 1.2 1.1 9.0 0.2 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 ETZ04417.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 ETZ04417.1 - 0.15 11.9 2.5 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 NTPase Transpeptidase PF00905.22 ETZ04418.1 - 3.5e-42 144.7 0.6 5e-42 144.2 0.6 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Beta-lactamase2 PF13354.6 ETZ04418.1 - 0.04 13.5 0.0 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 Beta-lactamase enzyme family tRNA_bind PF01588.20 ETZ04419.1 - 6.5e-09 35.8 0.0 7.4e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Putative tRNA binding domain AAA_28 PF13521.6 ETZ04420.1 - 2.7e-08 34.2 0.1 2.8e-08 34.2 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETZ04420.1 - 3e-05 24.6 0.1 3.5e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETZ04420.1 - 0.0067 16.7 0.0 0.0068 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ETZ04420.1 - 0.012 15.4 0.1 0.012 15.4 0.1 1.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ETZ04420.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 ETZ04420.1 - 0.016 14.5 0.0 0.016 14.5 0.0 1.0 1 0 0 1 1 1 0 P-loop ATPase protein family KTI12 PF08433.10 ETZ04420.1 - 0.017 14.6 0.0 0.017 14.6 0.0 1.0 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 ETZ04420.1 - 0.027 14.8 0.0 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ETZ04420.1 - 0.027 14.6 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 ETZ04420.1 - 0.029 13.3 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Herpes_Helicase PF02689.14 ETZ04420.1 - 0.031 12.2 0.0 0.031 12.2 0.0 1.0 1 0 0 1 1 1 0 Helicase AAA_19 PF13245.6 ETZ04420.1 - 0.033 14.5 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ETZ04420.1 - 0.05 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETZ04420.1 - 0.052 13.3 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ETZ04420.1 - 0.057 12.8 0.0 0.057 12.8 0.0 1.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 ETZ04420.1 - 0.059 13.0 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 ETZ04420.1 - 0.075 12.5 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 ETZ04420.1 - 0.078 12.1 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.9 ETZ04420.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ETZ04420.1 - 0.13 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 ETZ04420.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 ETZ04421.1 - 2.6e-07 31.0 0.0 3e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain SnoaL_3 PF13474.6 ETZ04422.1 - 0.00044 20.5 0.0 0.00049 20.3 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ETZ04422.1 - 0.015 15.9 0.0 0.016 15.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 ETZ04422.1 - 0.034 14.5 0.0 0.035 14.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MarR PF01047.22 ETZ04423.1 - 4.5e-06 26.5 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ETZ04423.1 - 0.00022 21.0 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ETZ04423.1 - 0.0011 19.4 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain EcKinase PF02958.20 ETZ04423.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 ETZ04423.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETZ04423.1 - 0.012 15.2 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RNA_pol_Rpb2_6 PF00562.28 ETZ04423.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 SnoaL_2 PF12680.7 ETZ04424.1 - 1.4e-10 41.7 0.1 1.7e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ETZ04424.1 - 1.3e-06 28.6 0.0 1.7e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ETZ04424.1 - 4e-05 24.0 0.0 4.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4904 PF16247.5 ETZ04424.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) MarR_2 PF12802.7 ETZ04425.1 - 3.8e-10 39.5 0.1 6.2e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ETZ04425.1 - 5.1e-09 35.9 0.0 8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ETZ04425.1 - 4.4e-08 33.5 0.0 7.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ETZ04425.1 - 1e-05 25.0 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ETZ04425.1 - 0.0017 18.1 0.1 0.004 16.9 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 ETZ04425.1 - 0.09 13.1 0.2 0.28 11.6 0.1 1.9 1 1 1 2 2 2 0 Transcriptional regulator TrmB PF01978.19 ETZ04425.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SMC_ScpB PF04079.16 ETZ04425.1 - 0.099 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB His_Phos_1 PF00300.22 ETZ04426.1 - 7.1e-26 91.1 0.0 8.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PrpR_N PF06506.11 ETZ04426.1 - 0.004 16.7 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 2 Propionate catabolism activator HTH_23 PF13384.6 ETZ04429.1 - 3.8e-05 23.3 0.7 5.1e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 ETZ04429.1 - 0.0021 18.0 0.1 0.0048 16.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ETZ04429.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rubrerythrin PF02915.17 ETZ04430.1 - 3.4e-27 95.5 2.6 7.3e-27 94.4 2.6 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 ETZ04430.1 - 6.6e-09 35.8 0.4 0.0028 17.6 0.4 2.1 1 1 1 2 2 2 2 Ferritin-like domain RadC PF04002.15 ETZ04431.1 - 1.1e-36 125.5 0.0 1.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 ETZ04431.1 - 0.00084 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Toxin-JAB1 PF15659.6 ETZ04431.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 JAB-like toxin 1 Rsbr_N PF08678.10 ETZ04432.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Rsbr N terminal Bax1-I PF01027.20 ETZ04434.1 - 1.4e-50 172.0 26.0 1.7e-50 171.7 26.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PAPS_reduct PF01507.19 ETZ04435.1 - 0.045 13.8 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF1013 PF06242.11 ETZ04436.1 - 1.8e-36 125.2 0.0 3.5e-36 124.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1013) HipA_C PF07804.12 ETZ04438.1 - 1.6e-43 148.9 0.0 2.1e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 ETZ04438.1 - 5.2e-18 65.5 0.0 1.2e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 HipA N-terminal domain HTH_3 PF01381.22 ETZ04439.1 - 3.5e-08 33.4 0.2 6.2e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ETZ04439.1 - 8.5e-05 22.8 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ETZ04439.1 - 0.00033 21.0 0.6 0.0008 19.8 0.3 1.9 2 1 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 ETZ04439.1 - 0.008 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ETZ04439.1 - 0.035 14.1 0.2 0.062 13.3 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Trp_repressor PF01371.19 ETZ04439.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein Pou PF00157.17 ETZ04439.1 - 0.072 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain gpW PF02831.15 ETZ04440.1 - 1.1e-06 28.4 0.1 1.3e-06 28.2 0.1 1.3 1 1 0 1 1 1 1 gpW AAA_lid_7 PF17867.1 ETZ04440.1 - 0.033 14.4 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 Midasin AAA lid domain Phage_portal_2 PF05136.13 ETZ04442.1 - 1.3e-104 350.3 0.0 1.7e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein, lambda family Peptidase_S49 PF01343.18 ETZ04443.1 - 1.7e-31 109.2 0.1 3.1e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 ETZ04443.1 - 8.5e-05 22.5 1.2 0.0005 20.0 0.2 2.5 3 0 0 3 3 3 1 Clp protease HDPD PF02924.14 ETZ04444.1 - 9.6e-19 67.6 0.2 1e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 Bacteriophage lambda head decoration protein D Aminotran_3 PF00202.21 ETZ04446.1 - 5.1e-106 354.7 0.0 6.2e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF4167 PF13763.6 ETZ04447.1 - 2.8e-20 72.2 0.8 3.3e-20 72.0 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4167) tRNA-synt_1b PF00579.25 ETZ04448.1 - 8.9e-72 241.9 0.0 1.2e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ETZ04448.1 - 9.7e-07 28.4 0.1 2.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 S4 domain Bul1_N PF04425.12 ETZ04450.1 - 0.0022 16.9 2.7 0.003 16.4 2.7 1.1 1 0 0 1 1 1 1 Bul1 N terminus TonB_2 PF13103.6 ETZ04450.1 - 0.01 16.1 0.0 0.041 14.1 0.0 2.0 2 0 0 2 2 2 0 TonB C terminal CNDH2_C PF16858.5 ETZ04450.1 - 0.034 14.0 6.4 0.042 13.7 6.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Virul_Fac PF10139.9 ETZ04450.1 - 0.48 8.6 2.7 0.6 8.3 2.7 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor Rgp1 PF08737.10 ETZ04450.1 - 0.49 9.5 9.1 0.71 9.0 9.1 1.2 1 0 0 1 1 1 0 Rgp1 Draxin PF15550.6 ETZ04450.1 - 2.1 8.2 11.1 3.5 7.4 11.1 1.3 1 1 0 1 1 1 0 Draxin AP3D1 PF06375.11 ETZ04450.1 - 5.6 7.2 26.7 30 4.8 26.9 1.8 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 Ndc1_Nup PF09531.10 ETZ04450.1 - 7.6 5.1 5.9 8.5 4.9 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ExbD PF02472.16 ETZ04451.1 - 3.5e-23 82.2 1.1 4.1e-23 82.0 1.1 1.1 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 ETZ04451.1 - 0.022 15.0 1.2 0.045 14.0 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) MotA_ExbB PF01618.16 ETZ04452.1 - 3.3e-34 117.4 0.4 5.7e-34 116.6 0.4 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2207 PF09972.9 ETZ04452.1 - 0.16 10.7 0.5 0.22 10.3 0.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_31 PF13847.6 ETZ04455.1 - 1.2e-14 54.3 0.0 3.8e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ETZ04455.1 - 2.1e-11 43.7 0.0 1.5e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ETZ04455.1 - 7.1e-11 42.7 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 ETZ04455.1 - 2.6e-07 30.3 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 ETZ04455.1 - 3.8e-07 30.0 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 ETZ04455.1 - 1.7e-06 27.6 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ETZ04455.1 - 2.7e-06 27.9 0.0 8.4e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ETZ04455.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 ETZ04455.1 - 4.6e-05 22.8 0.0 6.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 ETZ04455.1 - 0.00013 22.6 0.0 0.00039 21.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04455.1 - 0.0003 20.7 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ETZ04455.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 ETZ04455.1 - 0.0023 17.4 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 ETZ04455.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_Tnp_Tc5 PF03221.16 ETZ04455.1 - 0.012 15.7 0.2 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Methyltransf_2 PF00891.18 ETZ04455.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DDE_3 PF13358.6 ETZ04456.1 - 7.4e-15 55.0 0.0 8.7e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3741 PF12552.8 ETZ04457.1 - 0.033 14.2 0.2 0.089 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) RCSD PF05177.12 ETZ04457.1 - 0.7 10.8 9.2 0.74 10.8 7.5 1.8 1 1 1 2 2 2 0 RCSD region Polysacc_deac_1 PF01522.21 ETZ04458.1 - 3.7e-05 23.6 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETZ04458.1 - 0.0022 17.7 1.2 0.0033 17.1 1.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) MBOAT PF03062.19 ETZ04460.1 - 6.6e-27 94.8 19.3 6.6e-27 94.8 19.3 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ETZ04460.1 - 4.5e-05 23.6 1.7 0.00022 21.4 1.7 2.3 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Epimerase_2 PF02350.19 ETZ04461.1 - 1.3e-100 336.7 0.0 1.5e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 ETZ04461.1 - 0.0051 15.9 0.2 0.0069 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Glycos_transf_1 PF00534.20 ETZ04462.1 - 1.6e-16 60.3 0.1 3.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ04462.1 - 3.5e-13 50.1 0.0 6.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ04462.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Epimerase_2 PF02350.19 ETZ04462.1 - 0.085 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 ETZ04462.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Methyltransf_11 PF08241.12 ETZ04463.1 - 2e-16 60.4 0.0 3.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04463.1 - 1.6e-14 54.1 0.0 2.2e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04463.1 - 1.7e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04463.1 - 1.4e-12 48.2 0.0 2.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04463.1 - 2.7e-09 36.7 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETZ04463.1 - 3e-07 31.1 0.0 9e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ETZ04463.1 - 1.4e-05 24.6 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ETZ04463.1 - 6e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETZ04463.1 - 0.0025 17.4 0.0 0.0087 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 ETZ04463.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 1 1 2 2 2 0 DREV methyltransferase Methyltransf_11 PF08241.12 ETZ04464.1 - 1.7e-20 73.4 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04464.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04464.1 - 7.2e-15 55.5 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04464.1 - 6.7e-13 48.7 0.0 1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ04464.1 - 3.2e-12 47.1 0.0 5.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04464.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ETZ04464.1 - 4e-06 26.3 0.0 9.7e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ETZ04464.1 - 4.2e-06 26.5 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 ETZ04464.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.15 ETZ04464.1 - 0.034 14.0 0.1 0.52 10.1 0.0 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ETZ04465.1 - 9.4e-23 80.7 0.0 2.1e-22 79.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04465.1 - 3.2e-20 72.6 0.0 6.6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04465.1 - 6.4e-20 71.5 0.3 1e-19 70.8 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04465.1 - 1.2e-14 54.3 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETZ04465.1 - 4.4e-13 49.8 0.0 1.6e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04465.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETZ04465.1 - 1.5e-08 34.4 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ETZ04465.1 - 3.2e-06 26.3 0.0 4.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ETZ04465.1 - 5.2e-06 26.1 0.0 6e-05 22.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ETZ04465.1 - 5.9e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 ETZ04465.1 - 6e-06 25.8 0.4 8.4e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 ETZ04465.1 - 2e-05 24.3 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 ETZ04465.1 - 0.001 18.6 0.1 0.0014 18.2 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 ETZ04465.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ETZ04465.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04465.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 ETZ04465.1 - 0.004 16.9 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_4 PF02390.17 ETZ04465.1 - 0.0045 16.5 0.1 0.019 14.4 0.1 1.9 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 ETZ04465.1 - 0.012 15.5 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 ETZ04465.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 ETZ04465.1 - 0.014 15.0 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 ETZ04465.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF43 PF01861.16 ETZ04465.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain FemAB PF02388.16 ETZ04466.1 - 4.9e-15 55.3 5.6 6.2e-08 31.9 0.8 2.8 2 1 1 3 3 3 2 FemAB family Acetyltransf_6 PF13480.7 ETZ04466.1 - 1.2e-11 44.9 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04466.1 - 0.085 13.1 0.2 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family ABC_tran PF00005.27 ETZ04467.1 - 4.6e-29 101.7 0.0 7.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ04467.1 - 3.7e-08 33.1 0.9 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 ETZ04467.1 - 9.5e-08 32.0 11.4 1.4e-07 31.5 11.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_ATPase PF09818.9 ETZ04467.1 - 0.00014 20.8 0.7 0.0043 15.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DEAD PF00270.29 ETZ04467.1 - 0.00075 19.3 0.7 0.013 15.2 0.1 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETZ04467.1 - 0.0012 19.1 0.1 0.069 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETZ04467.1 - 0.003 17.3 0.2 0.0065 16.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 ETZ04467.1 - 0.0032 17.6 0.8 0.0065 16.6 0.3 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 ETZ04467.1 - 0.0055 15.8 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ETZ04467.1 - 0.0083 16.2 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ04467.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 ETZ04467.1 - 0.022 15.2 0.8 0.045 14.2 0.4 1.7 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 ETZ04467.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 ETZ04467.1 - 0.025 14.8 0.3 0.12 12.7 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ETZ04467.1 - 0.038 14.4 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 ETZ04467.1 - 0.078 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 ETZ04467.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.6 ETZ04467.1 - 0.13 12.1 1.5 1.2 8.8 0.3 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 ETZ04467.1 - 0.17 11.7 2.5 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 NTPase Fic_N PF13784.6 ETZ04469.1 - 1.7e-25 88.8 0.0 4.2e-25 87.6 0.0 1.7 2 0 0 2 2 1 1 Fic/DOC family N-terminal Fic PF02661.18 ETZ04469.1 - 1.5e-23 83.5 0.0 3.3e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family HTH_DeoR PF08220.12 ETZ04469.1 - 7.2e-05 22.5 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TrmB PF01978.19 ETZ04469.1 - 0.00014 21.6 0.1 0.00032 20.5 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Ribosomal_S25 PF03297.15 ETZ04469.1 - 0.00017 21.7 0.1 0.00031 20.9 0.1 1.4 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 ETZ04469.1 - 0.00055 19.4 0.5 0.0013 18.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ETZ04469.1 - 0.00056 19.8 0.2 0.0022 17.9 0.1 2.1 2 0 0 2 2 2 1 HTH domain MarR_2 PF12802.7 ETZ04469.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ETZ04469.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 ETZ04469.1 - 0.0038 17.0 0.1 0.079 12.8 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ETZ04469.1 - 0.0058 16.9 0.1 0.022 15.1 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulator Fe_dep_repress PF01325.19 ETZ04469.1 - 0.0072 16.5 0.2 0.024 14.8 0.0 2.1 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 ETZ04469.1 - 0.015 15.3 0.0 0.048 13.6 0.0 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain FtsK_gamma PF09397.10 ETZ04469.1 - 0.024 14.4 0.1 0.065 13.1 0.1 1.8 1 1 1 2 2 2 0 Ftsk gamma domain HTH_CodY PF08222.11 ETZ04469.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 CodY helix-turn-helix domain HTH_20 PF12840.7 ETZ04469.1 - 0.057 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 ETZ04469.1 - 0.09 12.8 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 ETZ04469.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain DUF5635 PF18685.1 ETZ04469.1 - 0.13 12.2 0.0 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5635) Acetyltransf_3 PF13302.7 ETZ04470.1 - 2.2e-21 76.9 0.0 2.5e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04470.1 - 1.8e-07 31.4 0.0 2.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ETZ04470.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain APH_6_hur PF04655.14 ETZ04471.1 - 2e-37 129.0 0.0 2.4e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 ETZ04471.1 - 1.7e-07 31.5 0.1 2.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETZ04471.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 ETZ04471.1 - 0.0094 15.2 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Fructosamine kinase HbrB PF08539.11 ETZ04473.1 - 0.022 14.8 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 HbrB-like TspO_MBR PF03073.15 ETZ04474.1 - 2.2e-38 131.3 22.9 2.7e-38 131.1 22.9 1.0 1 0 0 1 1 1 1 TspO/MBR family ASFV_J13L PF05568.11 ETZ04474.1 - 0.4 10.4 1.2 0.74 9.5 1.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein FAD_binding_4 PF01565.23 ETZ04475.1 - 8.2e-25 87.2 0.3 1.3e-24 86.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GDPD PF03009.17 ETZ04475.1 - 4.1e-19 69.3 0.0 1.4e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ALO PF04030.14 ETZ04475.1 - 0.006 16.4 0.2 0.026 14.3 0.2 2.0 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DUF1667 PF07892.11 ETZ04475.1 - 0.17 12.0 0.8 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) APH PF01636.23 ETZ04476.1 - 2.6e-06 27.5 0.3 3.3e-06 27.2 0.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ETZ04476.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF772 PF05598.11 ETZ04477.1 - 3e-06 27.1 0.0 9.2e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 ETZ04479.1 - 0.00037 20.2 0.0 0.00039 20.1 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ETZ04479.1 - 0.11 12.5 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Transposase DDE domain APH PF01636.23 ETZ04480.1 - 5.4e-14 52.7 0.0 8.6e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETZ04480.1 - 2.7e-05 23.8 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ETZ04480.1 - 0.0095 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 ETZ04480.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_S66 PF02016.15 ETZ04481.1 - 1.2e-28 99.6 0.0 1.9e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 ETZ04481.1 - 1.7e-27 96.4 0.0 3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain MarR PF01047.22 ETZ04481.1 - 0.072 13.0 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 MarR family RF3_C PF16658.5 ETZ04481.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Acetyltransf_1 PF00583.25 ETZ04483.1 - 2.3e-10 40.7 0.0 2.6e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ04483.1 - 3.9e-09 36.5 0.0 4.6e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ04483.1 - 1.3e-08 35.2 0.0 1.6e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ04483.1 - 1.9e-07 31.2 0.0 2.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ04483.1 - 0.0001 22.4 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ETZ04483.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 ETZ04483.1 - 0.04 13.5 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase UB2H PF14814.6 ETZ04483.1 - 0.072 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain Acetyltransf_1 PF00583.25 ETZ04485.1 - 1.5e-10 41.3 0.0 1.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04485.1 - 8.1e-10 39.0 0.1 1e-09 38.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ04485.1 - 1.2e-08 35.0 0.1 1.4e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ETZ04485.1 - 0.0011 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 ETZ04485.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ETZ04485.1 - 0.047 13.8 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 ETZ04485.1 - 0.048 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 ETZ04485.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BLYB PF05289.11 ETZ04485.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein APH PF01636.23 ETZ04486.1 - 7.6e-19 68.6 0.0 1.1e-18 68.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETZ04486.1 - 6.3e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 ETZ04486.1 - 0.0035 16.7 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 ETZ04486.1 - 0.029 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CENP-U PF13097.6 ETZ04486.1 - 0.14 12.1 0.4 0.21 11.5 0.4 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit HTH_24 PF13412.6 ETZ04488.1 - 1.9e-07 30.5 0.0 3.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ETZ04488.1 - 0.00047 20.0 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ETZ04488.1 - 0.0027 17.6 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 MarR family PHB_acc PF05233.13 ETZ04488.1 - 0.16 12.0 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 PHB accumulation regulatory domain NusG PF02357.19 ETZ04489.1 - 3.4e-16 59.5 0.0 6.9e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 ETZ04489.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 KOW motif ABC_tran PF00005.27 ETZ04490.1 - 4.6e-29 101.7 0.0 7.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ04490.1 - 3.7e-08 33.1 0.9 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 ETZ04490.1 - 9.5e-08 32.0 11.4 1.4e-07 31.5 11.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_ATPase PF09818.9 ETZ04490.1 - 0.00014 20.8 0.7 0.0043 15.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DEAD PF00270.29 ETZ04490.1 - 0.00075 19.3 0.7 0.013 15.2 0.1 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETZ04490.1 - 0.0012 19.1 0.1 0.069 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETZ04490.1 - 0.003 17.3 0.2 0.0065 16.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 ETZ04490.1 - 0.0032 17.6 0.8 0.0065 16.6 0.3 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 ETZ04490.1 - 0.0055 15.8 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ETZ04490.1 - 0.0083 16.2 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ04490.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 ETZ04490.1 - 0.022 15.2 0.8 0.045 14.2 0.4 1.7 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 ETZ04490.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 ETZ04490.1 - 0.025 14.8 0.3 0.12 12.7 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ETZ04490.1 - 0.038 14.4 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 ETZ04490.1 - 0.078 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 ETZ04490.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.6 ETZ04490.1 - 0.13 12.1 1.5 1.2 8.8 0.3 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 ETZ04490.1 - 0.17 11.7 2.5 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 NTPase FemAB PF02388.16 ETZ04491.1 - 4.9e-15 55.3 5.6 6.2e-08 31.9 0.8 2.8 2 1 1 3 3 3 2 FemAB family Acetyltransf_6 PF13480.7 ETZ04491.1 - 1.2e-11 44.9 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04491.1 - 0.085 13.1 0.2 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Methyltransf_11 PF08241.12 ETZ04492.1 - 9.4e-23 80.7 0.0 2.1e-22 79.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04492.1 - 3.2e-20 72.6 0.0 6.6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04492.1 - 6.4e-20 71.5 0.3 1e-19 70.8 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04492.1 - 1.2e-14 54.3 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETZ04492.1 - 4.4e-13 49.8 0.0 1.6e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04492.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETZ04492.1 - 1.5e-08 34.4 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ETZ04492.1 - 3.2e-06 26.3 0.0 4.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ETZ04492.1 - 5.2e-06 26.1 0.0 6e-05 22.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ETZ04492.1 - 5.9e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 ETZ04492.1 - 6e-06 25.8 0.4 8.4e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 ETZ04492.1 - 2e-05 24.3 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 ETZ04492.1 - 0.001 18.6 0.1 0.0014 18.2 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 ETZ04492.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ETZ04492.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04492.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 ETZ04492.1 - 0.004 16.9 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_4 PF02390.17 ETZ04492.1 - 0.0045 16.5 0.1 0.019 14.4 0.1 1.9 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 ETZ04492.1 - 0.012 15.5 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 ETZ04492.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 ETZ04492.1 - 0.014 15.0 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 ETZ04492.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF43 PF01861.16 ETZ04492.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_11 PF08241.12 ETZ04493.1 - 1.7e-20 73.4 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04493.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04493.1 - 7.2e-15 55.5 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04493.1 - 6.7e-13 48.7 0.0 1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ04493.1 - 3.2e-12 47.1 0.0 5.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04493.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ETZ04493.1 - 4e-06 26.3 0.0 9.7e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ETZ04493.1 - 4.2e-06 26.5 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 ETZ04493.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.15 ETZ04493.1 - 0.034 14.0 0.1 0.52 10.1 0.0 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ETZ04494.1 - 2e-16 60.4 0.0 3.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04494.1 - 1.6e-14 54.1 0.0 2.2e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04494.1 - 1.7e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04494.1 - 1.4e-12 48.2 0.0 2.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ04494.1 - 2.7e-09 36.7 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETZ04494.1 - 3e-07 31.1 0.0 9e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ETZ04494.1 - 1.4e-05 24.6 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ETZ04494.1 - 6e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETZ04494.1 - 0.0025 17.4 0.0 0.0087 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 ETZ04494.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 1 1 2 2 2 0 DREV methyltransferase Glycos_transf_1 PF00534.20 ETZ04495.1 - 1.6e-16 60.3 0.1 3.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ04495.1 - 3.5e-13 50.1 0.0 6.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ04495.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Epimerase_2 PF02350.19 ETZ04495.1 - 0.085 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 ETZ04495.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Epimerase_2 PF02350.19 ETZ04496.1 - 1.3e-100 336.7 0.0 1.5e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 ETZ04496.1 - 0.0051 15.9 0.2 0.0069 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF354) MBOAT PF03062.19 ETZ04497.1 - 6.6e-27 94.8 19.3 6.6e-27 94.8 19.3 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ETZ04497.1 - 4.5e-05 23.6 1.7 0.00022 21.4 1.7 2.3 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Polysacc_deac_1 PF01522.21 ETZ04499.1 - 3.7e-05 23.6 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETZ04499.1 - 0.0022 17.7 1.2 0.0033 17.1 1.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Acetyltransf_1 PF00583.25 ETZ04500.1 - 1.1e-13 51.5 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04500.1 - 2.3e-10 40.8 0.0 3.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ04500.1 - 3.9e-10 39.8 0.0 7.1e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETZ04500.1 - 0.00028 21.0 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ04500.1 - 0.0008 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ04500.1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ETZ04500.1 - 0.0074 16.2 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ETZ04500.1 - 0.038 14.7 0.0 0.052 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S21 PF01165.20 ETZ04501.1 - 1.3e-12 47.2 7.4 1.3e-12 47.2 7.4 1.6 1 1 1 2 2 2 1 Ribosomal protein S21 DDE_Tnp_1_2 PF13586.6 ETZ04502.1 - 6.3e-06 26.5 0.3 1.9e-05 25.0 0.3 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ETZ04502.1 - 0.0034 17.1 1.5 0.013 15.1 1.5 2.1 1 1 0 1 1 1 1 Transposase DDE domain CTP_transf_1 PF01148.20 ETZ04503.1 - 2.4e-33 116.1 13.4 3e-33 115.7 13.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2754 PF10953.8 ETZ04503.1 - 0.0056 16.9 1.4 0.0056 16.9 1.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2754) YibE_F PF07907.11 ETZ04503.1 - 2.1 7.8 12.1 3.1 7.2 12.1 1.2 1 0 0 1 1 1 0 YibE/F-like protein DUF3188 PF11384.8 ETZ04503.1 - 4.3 7.1 5.8 0.71 9.6 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) MafB19-deam PF14437.6 ETZ04504.1 - 1.9e-25 89.2 0.0 2.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 ETZ04504.1 - 2.2e-21 75.6 0.0 3.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 ETZ04504.1 - 0.0003 20.9 0.1 0.00053 20.1 0.1 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 ETZ04504.1 - 0.0032 17.6 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 ETZ04504.1 - 0.0049 17.0 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 NAD1 PF18778.1 ETZ04504.1 - 0.0067 16.5 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 ETZ04504.1 - 0.077 13.1 0.7 0.077 13.1 0.7 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase PrgI PF12666.7 ETZ04505.1 - 4.6 8.0 7.9 10 6.9 3.6 2.3 2 1 0 2 2 2 0 PrgI family protein HTH_Tnp_IS630 PF01710.16 ETZ04506.1 - 5.2e-06 26.5 0.6 7.9e-06 25.9 0.6 1.3 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 ETZ04506.1 - 0.025 14.2 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix MFS_1 PF07690.16 ETZ04507.1 - 2.5e-29 102.3 39.2 2.5e-29 102.3 39.2 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETZ04507.1 - 0.0044 15.4 11.5 0.024 13.0 1.4 2.9 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 ETZ04507.1 - 0.0059 16.0 20.8 0.028 13.7 20.7 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4096 PF13340.6 ETZ04509.1 - 4e-08 33.4 0.0 5.6e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) zf-CGNR PF11706.8 ETZ04509.1 - 0.1 12.4 0.8 0.55 10.1 0.0 2.3 3 0 0 3 3 3 0 CGNR zinc finger Tricorn_C1 PF14684.6 ETZ04510.1 - 5.8e-25 87.1 1.1 1.2e-24 86.1 1.1 1.6 1 0 0 1 1 1 1 Tricorn protease C1 domain Peptidase_S41 PF03572.18 ETZ04510.1 - 8.2e-25 87.3 0.0 2e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Tricorn_PDZ PF14685.6 ETZ04510.1 - 8.1e-08 32.1 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain ANAPC4_WD40 PF12894.7 ETZ04510.1 - 0.048 14.0 0.4 1.3 9.4 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain G0-G1_switch_2 PF15103.6 ETZ04510.1 - 0.16 12.4 1.2 1 9.8 0.0 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Peptidase_S66C PF17676.1 ETZ04511.1 - 4.2e-25 88.7 0.0 1.3e-24 87.1 0.0 1.8 2 0 0 2 2 2 1 LD-carboxypeptidase C-terminal domain Peptidase_S66 PF02016.15 ETZ04511.1 - 8.1e-21 74.4 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Fe-S_biosyn PF01521.20 ETZ04512.1 - 6.3e-16 58.6 0.0 7.6e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Methyltrans_RNA PF04452.14 ETZ04513.1 - 1.2e-45 155.6 0.0 1.4e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Mg_chelatase PF01078.21 ETZ04514.1 - 1.1e-81 273.2 0.0 1.5e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 ETZ04514.1 - 4.5e-35 120.1 0.0 7.9e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 ETZ04514.1 - 4.2e-18 65.8 0.2 7.9e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 ETZ04514.1 - 1.2e-09 37.6 0.0 5.6e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_5 PF07728.14 ETZ04514.1 - 2.5e-08 34.0 0.0 3.3e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ETZ04514.1 - 8.3e-06 25.6 0.0 0.0073 16.0 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 ETZ04514.1 - 1.7e-05 25.2 0.0 7e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETZ04514.1 - 0.002 17.7 0.1 0.021 14.4 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 ETZ04514.1 - 0.015 15.0 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETZ04514.1 - 0.03 14.5 0.3 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETZ04514.1 - 0.06 13.7 0.3 0.46 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 ETZ04514.1 - 0.063 13.8 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ETZ04514.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETZ04514.1 - 0.089 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_2 PF07724.14 ETZ04514.1 - 0.11 12.6 0.0 0.73 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ETZ04514.1 - 0.19 11.4 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SecD_SecF PF02355.16 ETZ04515.1 - 2.1e-16 59.9 9.6 4.1e-16 58.9 9.6 1.5 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 ETZ04515.1 - 7.3e-07 28.4 11.3 1.4e-06 27.5 11.3 1.5 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 ETZ04515.1 - 1.2e-06 27.8 0.0 2.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 ETZ04515.1 - 7e-06 24.0 15.4 1.6e-05 22.9 11.4 2.0 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family Glyco_hydro_106 PF17132.4 ETZ04515.1 - 0.062 11.6 0.7 0.085 11.1 0.7 1.1 1 0 0 1 1 1 0 alpha-L-rhamnosidase MgtE PF01769.16 ETZ04515.1 - 5.9 7.3 15.2 2 8.8 3.6 2.8 3 0 0 3 3 3 0 Divalent cation transporter SecD_SecF PF02355.16 ETZ04516.1 - 2.1e-52 177.3 6.3 2.1e-52 177.3 6.3 1.4 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 ETZ04516.1 - 5.8e-08 32.0 0.2 1.2e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif Bin3 PF06859.12 ETZ04516.1 - 0.11 13.1 0.1 5 7.8 0.0 2.4 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) DNA_pol_A_exo1 PF01612.20 ETZ04517.1 - 1.3e-29 103.2 0.0 1.6e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Pribosyltran PF00156.27 ETZ04518.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ETZ04518.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase PRTase_3 PF15610.6 ETZ04518.1 - 0.046 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like UPRTase PF14681.6 ETZ04518.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DZR PF12773.7 ETZ04518.1 - 1.1 9.3 4.7 0.65 10.1 1.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.6 ETZ04519.1 - 0.047 14.2 1.1 0.047 14.2 1.1 2.8 1 1 1 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 ETZ04519.1 - 0.59 10.1 11.1 0.5 10.4 9.3 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2 PF00096.26 ETZ04519.1 - 3.7 8.2 14.8 0.56 10.8 3.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type GTP_EFTU PF00009.27 ETZ04521.1 - 2.4e-30 105.6 12.2 4.5e-30 104.7 5.8 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ETZ04521.1 - 1.6e-27 95.7 1.2 5.3e-27 94.0 1.2 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ETZ04521.1 - 4.1e-11 43.0 1.2 3.4e-10 40.0 0.3 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase IF2_N PF04760.15 ETZ04521.1 - 1.2e-08 34.6 0.3 2.9e-08 33.4 0.3 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 ETZ04521.1 - 2e-06 28.1 0.5 0.02 15.3 0.0 3.5 3 0 0 3 3 2 2 Elongation factor Tu domain 2 PduV-EutP PF10662.9 ETZ04521.1 - 5.1e-06 26.3 0.3 1.4e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 ETZ04521.1 - 6.3e-06 25.7 0.2 6.3e-06 25.7 0.2 2.4 2 1 0 2 2 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ETZ04521.1 - 7.8e-05 22.3 2.0 0.00023 20.7 2.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 ETZ04521.1 - 0.00015 21.4 0.2 0.00038 20.1 0.2 1.7 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 ETZ04521.1 - 0.00024 21.1 6.3 0.019 14.8 0.4 3.1 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 ETZ04521.1 - 0.00099 19.3 0.1 0.0029 17.8 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETZ04521.1 - 0.0055 16.2 6.1 0.013 14.9 0.1 2.9 3 1 1 4 4 4 1 ADP-ribosylation factor family IF2_assoc PF08364.11 ETZ04521.1 - 0.013 15.7 4.9 0.053 13.8 4.9 2.0 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region SIS_2 PF13580.6 ETZ04521.1 - 0.015 15.4 0.2 0.075 13.1 0.1 2.2 2 0 0 2 2 2 0 SIS domain AAA_29 PF13555.6 ETZ04521.1 - 0.19 11.5 0.0 0.51 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ04521.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.4 2 1 1 3 3 2 0 AAA domain Dynamin_N PF00350.23 ETZ04521.1 - 5.1 7.1 11.1 4.3 7.4 0.1 3.7 2 2 1 3 3 2 0 Dynamin family Acetyltransf_6 PF13480.7 ETZ04523.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ins_allergen_rp PF06757.13 ETZ04523.1 - 0.28 11.1 5.2 1.3 9.0 0.1 3.9 4 1 0 4 4 4 0 Insect allergen related repeat, nitrile-specifier detoxification AAA_23 PF13476.6 ETZ04523.1 - 0.82 10.1 6.1 0.74 10.3 2.2 2.5 1 1 0 2 2 2 0 AAA domain PRD1_DD PF11087.8 ETZ04524.1 - 0.059 13.1 0.0 0.097 12.4 0.0 1.4 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery Rubrerythrin PF02915.17 ETZ04525.1 - 1e-27 97.2 1.8 2.1e-27 96.2 1.8 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 ETZ04525.1 - 7.4e-09 35.7 0.3 0.0028 17.6 0.5 2.1 1 1 1 2 2 2 2 Ferritin-like domain AAA_18 PF13238.6 ETZ04526.1 - 1.9e-06 28.4 0.4 4.1e-06 27.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 ETZ04526.1 - 2.1e-06 27.5 0.1 3.4e-06 26.9 0.1 1.3 1 1 0 1 1 1 1 Guanylate kinase Thymidylate_kin PF02223.17 ETZ04526.1 - 0.0023 17.7 0.9 0.53 9.9 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 ETZ04526.1 - 0.018 14.9 2.3 2.1 8.1 0.2 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_33 PF13671.6 ETZ04526.1 - 0.046 13.9 0.2 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 ETZ04526.1 - 0.51 10.4 2.0 5.7 7.0 2.0 2.5 1 1 0 1 1 1 0 Cytidylate kinase-like family GTP_EFTU PF00009.27 ETZ04527.1 - 2e-51 174.3 0.1 3.4e-51 173.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ETZ04527.1 - 3.6e-48 162.2 0.2 7.8e-48 161.1 0.2 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ETZ04527.1 - 6.5e-18 64.6 0.0 1.5e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ETZ04527.1 - 1.7e-08 34.4 0.0 5.4e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ETZ04527.1 - 9.1e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ETZ04527.1 - 4.6e-06 26.9 0.2 1.2e-05 25.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 ETZ04527.1 - 0.00036 20.2 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.9 ETZ04527.1 - 0.00096 18.9 0.1 0.0038 17.0 0.2 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 ETZ04527.1 - 0.0011 18.5 0.3 0.0032 17.0 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RF3_C PF16658.5 ETZ04527.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AAA_23 PF13476.6 ETZ04527.1 - 0.01 16.4 0.1 0.021 15.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 ETZ04527.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 ETZ04527.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase KAP PF05804.12 ETZ04527.1 - 0.12 10.5 0.1 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) ATP_bind_3 PF01171.20 ETZ04527.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 PP-loop family Lactamase_B_2 PF12706.7 ETZ04528.1 - 1.8e-22 79.9 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETZ04528.1 - 5e-07 29.9 0.0 8.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 ETZ04528.1 - 0.13 12.2 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain adh_short_C2 PF13561.6 ETZ04529.1 - 3e-57 193.9 0.0 3.4e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ04529.1 - 2.4e-54 183.8 0.0 2.8e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ04529.1 - 3.3e-13 50.0 0.1 5.3e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETZ04529.1 - 0.0063 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETZ04529.1 - 0.0087 16.0 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETZ04529.1 - 0.031 13.8 0.0 0.091 12.3 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 ETZ04529.1 - 0.043 13.2 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SmpB PF01668.18 ETZ04530.1 - 3e-51 173.1 2.2 3.4e-51 172.9 2.2 1.0 1 0 0 1 1 1 1 SmpB protein Ph1570 PF09638.10 ETZ04530.1 - 0.018 14.9 0.1 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 Ph1570 protein SPOR PF05036.13 ETZ04530.1 - 0.061 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Sporulation related domain NMO PF03060.15 ETZ04531.1 - 7.8e-09 35.4 0.0 1.4e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase N_methyl PF07963.12 ETZ04532.1 - 0.0013 18.2 0.1 0.0023 17.4 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GatB_N PF02934.15 ETZ04534.1 - 4.1e-104 347.8 0.0 2e-103 345.5 0.0 1.9 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ETZ04534.1 - 9.1e-29 100.3 1.3 1.4e-28 99.7 1.3 1.3 1 0 0 1 1 1 1 GatB domain DUF520 PF04461.13 ETZ04534.1 - 0.08 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF520) TFIIE_beta PF02186.15 ETZ04534.1 - 0.15 12.4 0.3 0.61 10.4 0.3 2.0 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF2802 PF10975.8 ETZ04534.1 - 2.5 8.3 5.7 26 5.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) Pyr_redox_2 PF07992.14 ETZ04536.1 - 3.8e-44 151.1 0.4 4.3e-44 150.9 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETZ04536.1 - 2.3e-20 73.1 0.7 5.5e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETZ04536.1 - 4.3e-16 59.2 1.5 3.2e-13 50.1 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETZ04536.1 - 9.7e-08 32.0 5.5 0.033 13.8 0.0 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.14 ETZ04536.1 - 3e-07 29.5 0.7 0.08 11.6 0.1 3.5 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 ETZ04536.1 - 2.1e-06 27.9 0.4 1.6e-05 25.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETZ04536.1 - 2.9e-06 26.7 1.1 0.011 15.0 0.1 3.2 2 1 1 3 3 3 2 Thi4 family GIDA PF01134.22 ETZ04536.1 - 1.6e-05 24.2 5.4 0.016 14.3 0.7 3.8 2 2 2 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETZ04536.1 - 1.7e-05 24.1 4.9 0.0008 18.6 0.5 3.1 2 1 2 4 4 4 2 FAD binding domain FMO-like PF00743.19 ETZ04536.1 - 0.00031 19.3 0.0 0.00054 18.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 ETZ04536.1 - 0.00082 18.7 0.7 0.087 12.1 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 ETZ04536.1 - 0.0051 16.8 0.1 2.5 8.0 0.1 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 ETZ04536.1 - 0.0067 16.5 0.1 0.13 12.3 0.0 2.9 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ETZ04536.1 - 0.0079 16.6 0.0 0.51 10.8 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 ETZ04536.1 - 0.012 14.8 0.5 0.39 9.8 0.0 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ETZ04536.1 - 0.063 12.6 1.9 0.3 10.4 0.6 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETZ04536.1 - 0.34 10.9 5.1 22 5.0 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding RuvC PF02075.17 ETZ04537.1 - 1.3e-36 125.7 0.0 1.4e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF5446 PF17522.2 ETZ04537.1 - 0.057 13.6 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) RecO_N PF11967.8 ETZ04538.1 - 1.1e-06 28.5 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Recombination protein O N terminal RecO_C PF02565.15 ETZ04538.1 - 0.034 14.0 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Recombination protein O C terminal DDE_3 PF13358.6 ETZ04540.1 - 0.00093 19.0 0.0 0.00099 18.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FH2 PF02181.23 ETZ04541.1 - 0.024 13.8 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Radical_SAM PF04055.21 ETZ04542.1 - 1.4e-29 103.6 0.1 8.6e-29 101.1 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 ETZ04542.1 - 4.2e-26 90.9 0.1 7.9e-26 90.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 ETZ04542.1 - 4.4e-05 23.4 0.0 0.00012 22.0 0.0 1.8 2 0 0 2 2 2 1 TRAM domain Acyltransferase PF01553.21 ETZ04543.1 - 2.1e-17 63.0 0.2 4.3e-17 62.0 0.1 1.5 2 0 0 2 2 2 1 Acyltransferase Acetyltransf_5 PF13444.6 ETZ04544.1 - 4.2e-29 101.2 0.2 6.6e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 ETZ04544.1 - 0.00048 19.7 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Autoinducer synthase Acetyltransf_10 PF13673.7 ETZ04544.1 - 0.066 13.2 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SecB PF02556.14 ETZ04545.1 - 1.4e-20 73.6 0.0 1.8e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB Ala_racemase_N PF01168.20 ETZ04548.1 - 8.7e-54 182.5 0.0 1.3e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 ETZ04548.1 - 4.1e-30 104.1 0.0 5.9e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain DNA_mis_repair PF01119.19 ETZ04549.1 - 1.2e-29 102.4 0.0 2.3e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 ETZ04549.1 - 2e-28 99.0 0.0 3.4e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 ETZ04549.1 - 7.2e-14 51.8 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ETZ04549.1 - 2.3e-07 31.3 0.0 4.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1827 PF08860.10 ETZ04551.1 - 0.035 14.3 0.0 0.035 14.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1827) Rotamase PF00639.21 ETZ04551.1 - 0.044 14.7 8.6 0.069 14.1 0.2 3.3 1 1 2 3 3 3 0 PPIC-type PPIASE domain CbiK PF06180.11 ETZ04551.1 - 0.11 11.9 4.8 0.47 9.7 0.1 2.5 1 1 1 2 2 2 0 Cobalt chelatase (CbiK) H-kinase_dim PF02895.14 ETZ04551.1 - 1.7 9.1 10.4 15 6.0 0.0 3.8 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain WHEP-TRS PF00458.20 ETZ04551.1 - 6.4 7.0 9.9 14 5.9 0.6 3.0 2 0 0 2 2 2 0 WHEP-TRS domain DDE_3 PF13358.6 ETZ04552.1 - 1.4e-09 37.8 0.0 1.5e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_transf_25 PF01755.17 ETZ04553.1 - 1.3e-17 64.4 0.0 4.3e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Methyltransf_25 PF13649.6 ETZ04554.1 - 2.5e-08 34.5 0.0 4.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ04554.1 - 2.4e-05 24.9 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ETZ04554.1 - 6.7e-05 22.1 0.0 7.9e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 ETZ04554.1 - 0.00053 20.7 0.0 0.00087 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETZ04554.1 - 0.00083 19.2 0.0 0.001 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ETZ04554.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ETZ04554.1 - 0.0018 18.1 0.0 0.0054 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ETZ04554.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ETZ04554.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 ETZ04554.1 - 0.22 11.0 0.1 0.5 9.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase RuvX PF03652.15 ETZ04555.1 - 5.8e-27 94.7 0.0 7.1e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Holliday junction resolvase GreA_GreB_N PF03449.15 ETZ04556.1 - 1.7e-26 92.2 4.5 2.8e-26 91.5 4.5 1.4 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 ETZ04556.1 - 8e-22 76.9 0.3 1.1e-21 76.4 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Sua5_yciO_yrdC PF01300.18 ETZ04558.1 - 5.9e-45 153.0 0.0 7.8e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ETZ04558.1 - 5.6e-15 56.1 0.0 2.3e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding KaiA PF07688.12 ETZ04559.1 - 0.016 15.3 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 KaiA C-terminal domain EloA-BP1 PF15870.5 ETZ04559.1 - 0.077 13.2 1.9 0.13 12.5 1.9 1.3 1 0 0 1 1 1 0 ElonginA binding-protein 1 DDE_3 PF13358.6 ETZ04560.1 - 1.3e-15 57.4 0.1 1.5e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve_3 PF13683.6 ETZ04560.1 - 0.00051 19.8 0.1 0.00077 19.2 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.11 ETZ04560.1 - 0.0041 16.1 0.3 0.0042 16.1 0.3 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain CxC4 PF18717.1 ETZ04560.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases DUF1965 PF09248.10 ETZ04560.1 - 0.022 14.5 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) HTH_33 PF13592.6 ETZ04561.1 - 1.6e-13 50.0 0.0 2.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 ETZ04563.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ETZ04563.1 - 0.00039 20.1 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 ETZ04563.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_AsnC-type PF13404.6 ETZ04563.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ETZ04563.1 - 0.038 13.9 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 ETZ04563.1 - 0.048 13.8 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ETZ04563.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 HTH domain TetR_N PF00440.23 ETZ04563.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.12 ETZ04563.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Bac_GH3_C PF18034.1 ETZ04563.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain HTH_psq PF05225.16 ETZ04563.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain E1_dh PF00676.20 ETZ04565.1 - 2e-75 253.6 0.0 2.5e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ETZ04565.1 - 4.2e-06 26.2 0.1 1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ETZ04565.1 - 0.00025 20.9 0.4 0.0021 17.8 0.4 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RhoGEF PF00621.20 ETZ04565.1 - 0.13 12.5 0.2 22 5.2 0.0 2.2 2 0 0 2 2 2 0 RhoGEF domain Response_reg PF00072.24 ETZ04566.1 - 1.2e-18 67.2 0.0 2.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ETZ04566.1 - 2.6e-17 63.3 0.0 4.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETZ04566.1 - 1.8e-08 34.3 0.0 4.5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ETZ04566.1 - 0.0047 17.2 0.0 4.1 7.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold HATPase_c_5 PF14501.6 ETZ04566.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 GHKL domain PAS PF00989.25 ETZ04566.1 - 0.11 12.5 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 PAS fold Secretin PF00263.21 ETZ04567.1 - 3.8e-27 95.0 0.4 6e-27 94.4 0.4 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein TPR_19 PF14559.6 ETZ04567.1 - 6.4e-07 29.8 6.2 0.021 15.3 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETZ04567.1 - 3.9e-05 23.4 17.0 0.55 10.5 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ04567.1 - 0.00011 22.7 4.0 0.0015 19.2 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETZ04567.1 - 0.0085 15.8 7.8 0.058 13.1 1.1 3.8 3 0 0 3 3 3 1 TPR repeat YfiO PF13525.6 ETZ04567.1 - 0.02 14.6 3.3 0.042 13.6 3.3 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_17 PF13431.6 ETZ04567.1 - 0.024 15.0 7.8 0.053 13.9 0.3 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETZ04567.1 - 0.061 13.6 5.8 0.3 11.4 1.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 ETZ04567.1 - 0.075 13.2 0.1 3.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETZ04567.1 - 0.14 12.4 4.1 0.23 11.7 2.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ETZ04567.1 - 3.3 8.8 6.1 7.7 7.6 0.4 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Secretin PF00263.21 ETZ04568.1 - 4.5e-21 75.2 3.1 6.8e-21 74.6 3.1 1.2 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein TPR_9 PF13371.6 ETZ04568.1 - 5.8e-07 29.6 0.2 0.023 14.8 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETZ04568.1 - 1.1e-05 25.9 3.1 0.052 14.1 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETZ04568.1 - 5.1e-05 23.1 0.3 0.12 12.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETZ04568.1 - 0.045 13.5 2.7 18 5.1 0.1 4.0 4 0 0 4 4 4 0 TPR repeat Fis1_TPR_C PF14853.6 ETZ04568.1 - 0.062 13.4 3.3 33 4.7 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 ETZ04568.1 - 0.17 11.5 0.0 0.48 10.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 ETZ04568.1 - 0.21 11.8 2.5 0.44 10.8 0.9 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MipZ PF09140.11 ETZ04569.1 - 6e-60 202.7 0.0 7.2e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 ATPase MipZ CbiA PF01656.23 ETZ04569.1 - 1.3e-06 28.4 0.0 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ETZ04569.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 ETZ04569.1 - 3.6e-05 23.8 0.1 0.0014 18.6 0.0 2.4 1 1 0 2 2 2 1 AAA domain VirC1 PF07015.11 ETZ04569.1 - 0.0001 21.7 0.0 0.00022 20.6 0.0 1.5 1 1 0 1 1 1 1 VirC1 protein AAA_25 PF13481.6 ETZ04569.1 - 0.0013 18.3 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETZ04569.1 - 0.0042 16.8 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Glyco_transf_34 PF05637.12 ETZ04569.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family ArsA_ATPase PF02374.15 ETZ04569.1 - 0.13 11.4 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase BPD_transp_1 PF00528.22 ETZ04570.1 - 1.2e-12 48.0 20.0 1.6e-12 47.6 20.0 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF1218 PF06749.12 ETZ04570.1 - 1.4 9.5 6.4 0.51 10.9 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) HTH_Tnp_IS630 PF01710.16 ETZ04571.1 - 2.9e-09 37.0 0.0 3.6e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ETZ04571.1 - 0.059 13.5 0.0 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_Tnp_1_2 PF13586.6 ETZ04572.1 - 1.8e-05 25.0 0.0 2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Pox_G7 PF05503.12 ETZ04573.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like GFO_IDH_MocA PF01408.22 ETZ04575.1 - 1.2e-16 61.6 0.1 2.1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ETZ04575.1 - 0.00092 19.5 0.0 0.01 16.1 0.0 2.5 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_2 PF03446.15 ETZ04575.1 - 0.0032 17.7 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETZ04575.1 - 0.03 14.9 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_18 PF13238.6 ETZ04576.1 - 6.8e-07 29.9 0.8 2.1e-06 28.3 0.8 1.8 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 ETZ04576.1 - 2.1e-05 24.3 0.4 4.1e-05 23.3 0.4 1.5 1 1 0 1 1 1 1 Guanylate kinase PRK PF00485.18 ETZ04576.1 - 0.0012 18.6 0.1 0.08 12.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 ETZ04576.1 - 0.014 14.7 1.3 0.062 12.6 1.3 1.8 1 1 0 1 1 1 0 Zeta toxin dNK PF01712.19 ETZ04576.1 - 0.026 14.4 1.7 1.1 9.0 1.1 2.5 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_33 PF13671.6 ETZ04576.1 - 0.031 14.4 2.1 0.42 10.8 2.1 2.6 1 1 0 1 1 1 0 AAA domain PPK2 PF03976.14 ETZ04576.1 - 0.054 13.0 0.2 0.073 12.6 0.2 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Thymidylate_kin PF02223.17 ETZ04576.1 - 0.22 11.2 2.7 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin2 PF13189.6 ETZ04576.1 - 0.24 11.5 2.0 5.4 7.1 2.0 2.5 1 1 0 1 1 1 0 Cytidylate kinase-like family Rubrerythrin PF02915.17 ETZ04577.1 - 3.4e-27 95.5 2.6 7.3e-27 94.4 2.6 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 ETZ04577.1 - 6.6e-09 35.8 0.4 0.0028 17.6 0.4 2.1 1 1 1 2 2 2 2 Ferritin-like domain Bac_DNA_binding PF00216.21 ETZ04578.1 - 8.1e-24 83.6 0.0 1.1e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 ETZ04578.1 - 2.4e-05 24.1 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-HIG PF18291.1 ETZ04578.1 - 4.1e-05 23.7 0.0 4.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 ETZ04578.1 - 0.008 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 PIEZO PF15917.5 ETZ04580.1 - 0.0063 16.0 2.2 0.01 15.3 2.2 1.3 1 0 0 1 1 1 1 Piezo MlaA PF04333.13 ETZ04581.1 - 3.9e-49 167.0 0.0 4.8e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 MlaA lipoprotein CDP-OH_P_transf PF01066.21 ETZ04582.1 - 5.3e-13 49.5 0.4 5.3e-13 49.5 0.4 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M22 PF00814.25 ETZ04583.1 - 4.4e-78 262.7 0.0 5.2e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family tRNA-synt_1f PF01921.18 ETZ04584.1 - 3.9e-122 407.7 0.0 4.6e-122 407.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.11 ETZ04584.1 - 0.0042 15.9 0.0 0.0078 15.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ETZ04584.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ABC1 PF03109.16 ETZ04585.1 - 8.8e-18 64.6 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ETZ04585.1 - 3.8e-05 23.7 0.2 0.0006 19.8 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 ETZ04585.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Glucos_trans_II PF14264.6 ETZ04585.1 - 0.052 12.9 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Glucosyl transferase GtrII tRNA-synt_2e PF02091.15 ETZ04587.1 - 4.8e-113 377.0 0.0 5.4e-113 376.8 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit PolyA_pol PF01743.20 ETZ04588.1 - 6.5e-26 91.2 0.0 9.5e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ETZ04588.1 - 3.7e-07 29.8 0.1 1.3e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A MreB_Mbl PF06723.13 ETZ04589.1 - 4.6e-131 436.5 4.0 5.3e-131 436.3 4.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 ETZ04589.1 - 1.7e-14 53.0 2.4 4e-13 48.4 0.2 2.7 2 1 0 2 2 2 1 Hsp70 protein Actin PF00022.19 ETZ04589.1 - 2.2e-11 43.0 0.1 2.2e-08 33.1 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 ETZ04589.1 - 3.9e-08 33.7 1.0 1.8e-07 31.5 0.1 2.3 2 1 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 ETZ04589.1 - 3.3e-07 29.7 0.1 0.009 15.1 0.0 3.0 2 1 1 3 3 3 2 Type IV pilus assembly protein PilM; EutA PF06277.11 ETZ04589.1 - 0.00028 19.9 0.4 0.0028 16.6 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA Ppx-GppA PF02541.16 ETZ04589.1 - 0.0016 17.9 0.5 0.007 15.8 0.2 2.1 3 0 0 3 3 3 1 Ppx/GppA phosphatase family StbA PF06406.11 ETZ04589.1 - 0.0019 17.5 0.4 0.024 13.9 0.3 2.2 1 1 0 1 1 1 1 StbA protein DDR PF08841.10 ETZ04589.1 - 0.0039 16.2 0.7 0.011 14.8 0.4 1.8 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 ETZ04589.1 - 0.024 14.2 2.7 0.44 10.0 0.0 2.4 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEAD PF00270.29 ETZ04590.1 - 1e-14 54.7 0.1 7.5e-14 51.9 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETZ04590.1 - 8.5e-12 45.4 0.0 3.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecG_wedge PF17191.4 ETZ04590.1 - 2.5e-09 37.0 0.0 4.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RecG wedge domain ResIII PF04851.15 ETZ04590.1 - 4.8e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 ETZ04590.1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Hexapep PF00132.24 ETZ04591.1 - 2.2e-18 65.2 0.9 2.1e-05 24.0 0.0 4.4 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ETZ04591.1 - 4.5e-15 56.4 0.0 7.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ETZ04591.1 - 3e-08 33.3 2.0 2.7e-06 27.0 0.0 3.7 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 ETZ04591.1 - 0.0003 20.6 0.0 0.00072 19.4 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 ETZ04591.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase NAD_kinase PF01513.21 ETZ04592.1 - 2.3e-07 30.3 0.0 1.5e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase UDPG_MGDP_dh_N PF03721.14 ETZ04593.1 - 8.8e-30 103.7 0.0 1.4e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ETZ04593.1 - 1.1e-22 80.1 0.0 1.8e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ETZ04593.1 - 3.5e-15 56.3 0.0 8.7e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 ETZ04593.1 - 0.0042 17.3 0.0 0.025 14.8 0.0 2.4 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase MauJ PF17419.2 ETZ04593.1 - 0.055 12.9 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylamine utilization protein MauJ ArsR PF09824.9 ETZ04593.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 ArsR transcriptional regulator Epimerase PF01370.21 ETZ04594.1 - 4.3e-42 144.2 0.0 5.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETZ04594.1 - 1e-39 136.9 0.0 1.2e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETZ04594.1 - 6.3e-12 45.1 0.0 8.4e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETZ04594.1 - 7e-10 38.5 0.0 4.7e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ETZ04594.1 - 1.6e-09 37.3 0.0 2.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETZ04594.1 - 2.4e-07 30.2 1.4 2.2e-06 27.1 0.7 2.6 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 ETZ04594.1 - 3.5e-05 23.8 0.0 0.00013 22.0 0.0 1.9 2 1 0 2 2 2 1 KR domain Autoind_bind PF03472.15 ETZ04594.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain adh_short PF00106.25 ETZ04594.1 - 0.05 13.0 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase MarR PF01047.22 ETZ04596.1 - 0.0015 18.4 0.1 0.0053 16.6 0.1 1.9 1 1 1 2 2 2 1 MarR family MarR_2 PF12802.7 ETZ04596.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ETZ04596.1 - 0.02 15.4 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.12 ETZ04596.1 - 0.076 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DDE_Tnp_IS1 PF03400.13 ETZ04597.1 - 9e-10 39.0 1.6 1.1e-09 38.7 1.6 1.1 1 0 0 1 1 1 1 IS1 transposase Rsbr_N PF08678.10 ETZ04598.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Rsbr N terminal MurB_C PF02873.16 ETZ04600.1 - 1.2e-23 83.4 0.0 2.4e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 ETZ04600.1 - 1.8e-19 69.9 0.1 6.3e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Mur_ligase_M PF08245.12 ETZ04601.1 - 2.1e-22 80.1 0.0 4.1e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ETZ04601.1 - 3.5e-22 78.4 0.0 4.4e-21 74.9 0.0 2.6 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 ETZ04601.1 - 2.2e-20 72.8 0.0 4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, catalytic domain BRCT PF00533.26 ETZ04601.1 - 9.9e-05 22.6 0.0 0.00022 21.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain F420_oxidored PF03807.17 ETZ04601.1 - 0.045 14.3 0.1 0.39 11.3 0.0 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ETZ04601.1 - 0.15 11.5 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_tran_28_C PF04101.16 ETZ04602.1 - 9.3e-24 84.3 0.0 2e-23 83.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 ETZ04602.1 - 3.4e-13 49.8 0.0 7.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain DDE_Tnp_1 PF01609.21 ETZ04603.1 - 0.019 14.6 0.0 0.021 14.5 0.0 1.0 1 0 0 1 1 1 0 Transposase DDE domain ABC_tran PF00005.27 ETZ04605.1 - 7e-31 107.6 0.0 2.4e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ETZ04605.1 - 3.3e-08 33.7 0.5 0.0089 15.9 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ04605.1 - 0.00043 19.8 0.1 0.54 9.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ETZ04605.1 - 0.0019 18.4 0.1 0.017 15.4 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit BCA_ABC_TP_C PF12399.8 ETZ04605.1 - 0.0044 16.9 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_29 PF13555.6 ETZ04605.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain OstA PF03968.14 ETZ04606.1 - 7.8e-09 35.7 0.5 2.3e-05 24.5 0.0 3.2 1 1 1 2 2 2 2 OstA-like protein OstA_2 PF13100.6 ETZ04606.1 - 4.5e-05 23.1 0.1 0.57 9.8 0.0 3.1 2 1 1 3 3 3 3 OstA-like protein LptC PF06835.13 ETZ04606.1 - 0.00077 19.1 0.1 0.098 12.2 0.0 2.9 2 1 0 3 3 3 1 Lipopolysaccharide-assembly, LptC-related Reductase_C PF14759.6 ETZ04606.1 - 0.088 13.4 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Reductase C-terminal PRP3 PF08572.10 ETZ04607.1 - 0.04 13.6 0.8 0.041 13.6 0.8 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Ribonuc_red_lgC PF02867.15 ETZ04608.1 - 7.2e-106 354.8 0.0 6.5e-68 229.5 0.0 2.2 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ETZ04608.1 - 3.1e-12 46.3 0.1 2.6e-11 43.4 0.1 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain FBPase_2 PF06874.11 ETZ04608.1 - 0.14 10.4 0.1 0.22 9.8 0.1 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Ribonuc_red_sm PF00268.21 ETZ04609.1 - 2.9e-65 220.5 2.0 4e-65 220.1 2.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain tRNA-synt_1 PF00133.22 ETZ04611.1 - 2e-184 614.2 2.3 4e-183 610.0 2.3 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ETZ04611.1 - 5.3e-27 94.6 0.5 1.4e-26 93.3 0.5 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ETZ04611.1 - 5.6e-25 87.9 0.6 2e-08 33.4 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 ETZ04611.1 - 8.4e-09 35.6 0.9 1.8e-08 34.5 0.9 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 ETZ04611.1 - 1.1e-08 34.8 0.0 7.4e-06 25.6 0.1 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ETZ04611.1 - 0.0037 16.7 0.0 0.99 8.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ADIP PF11559.8 ETZ04611.1 - 0.017 15.2 1.5 0.033 14.3 1.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding tRNA-synt_1f PF01921.18 ETZ04611.1 - 0.024 13.5 0.0 0.074 12.0 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (K) CdiI_2 PF18593.1 ETZ04611.1 - 0.076 13.7 0.4 0.3 11.8 0.1 2.2 2 0 0 2 2 2 0 CdiI immunity protein tRNA-synt_1d PF00750.19 ETZ04611.1 - 0.12 11.3 0.7 2.9 6.7 0.0 3.2 4 0 0 4 4 4 0 tRNA synthetases class I (R) Mur_ligase_M PF08245.12 ETZ04613.1 - 8.3e-29 100.9 0.0 1.9e-27 96.5 0.0 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ETZ04613.1 - 8.7e-19 67.6 0.0 2.9e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain BolA PF01722.18 ETZ04614.1 - 2.7e-14 53.2 0.0 3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein SAICAR_synt PF01259.18 ETZ04615.1 - 4.5e-08 33.0 0.0 6.7e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 SAICAR synthetase Colicin_V PF02674.16 ETZ04616.1 - 4.3e-24 85.1 5.3 5.3e-24 84.8 5.3 1.2 1 0 0 1 1 1 1 Colicin V production protein RhodobacterPufX PF11511.8 ETZ04616.1 - 0.096 12.3 0.6 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 Intrinsic membrane protein PufX PIG-Y PF15159.6 ETZ04616.1 - 3.7 8.6 7.5 27 5.8 6.6 2.4 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TcpE PF12648.7 ETZ04616.1 - 8.5 7.0 7.7 2.4 8.8 0.3 2.2 2 0 0 2 2 2 0 TcpE family TPR_1 PF00515.28 ETZ04617.1 - 4.7e-06 26.2 0.7 0.00022 20.9 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ04617.1 - 6.3e-06 26.8 0.0 4.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETZ04617.1 - 0.00012 22.0 4.3 0.0023 17.9 1.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETZ04617.1 - 0.0002 21.8 0.4 1.1 10.1 0.3 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat PknG_TPR PF16918.5 ETZ04617.1 - 0.00063 18.6 0.0 0.00086 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 ETZ04617.1 - 0.0016 18.6 3.3 0.016 15.4 0.3 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ETZ04617.1 - 0.0039 17.4 1.1 0.11 12.8 0.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETZ04617.1 - 0.024 15.1 0.1 4.9 7.7 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETZ04617.1 - 0.024 14.6 0.1 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETZ04617.1 - 0.025 14.8 3.0 6.8 7.2 0.7 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 ETZ04617.1 - 0.029 14.1 1.5 0.3 10.8 0.1 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF4988 PF16378.5 ETZ04617.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function TPR_3 PF07720.12 ETZ04617.1 - 0.11 12.5 2.0 0.24 11.4 1.5 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 ETZ04617.1 - 0.19 12.2 1.7 0.6 10.6 0.1 2.7 4 0 0 4 4 3 0 Tetratricopeptide repeat FYRC PF05965.14 ETZ04618.1 - 0.00052 20.1 0.2 0.11 12.6 0.1 2.4 1 1 1 2 2 2 2 F/Y rich C-terminus DUF4899 PF16240.5 ETZ04618.1 - 0.014 14.6 4.0 0.2 10.8 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4899) NAPRTase_N PF17767.1 ETZ04618.1 - 0.2 12.1 5.1 0.6 10.5 0.6 2.6 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain HTH_23 PF13384.6 ETZ04619.1 - 1.9e-06 27.5 0.0 4.5e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ETZ04619.1 - 0.00016 21.3 0.1 0.00082 19.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Terminase_5 PF06056.12 ETZ04619.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 ETZ04619.1 - 0.0043 17.2 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.16 ETZ04619.1 - 0.0078 15.9 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_38 PF13936.6 ETZ04619.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 ETZ04619.1 - 0.026 14.2 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 ETZ04619.1 - 0.037 13.4 0.1 0.081 12.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 P22_Cro PF14549.6 ETZ04619.1 - 0.06 13.2 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro HTH_AsnC-type PF13404.6 ETZ04619.1 - 0.1 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_ECF PF07638.11 ETZ04619.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor Homez PF11569.8 ETZ04620.1 - 0.00012 21.4 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_Tnp_IS630 PF01710.16 ETZ04620.1 - 0.0021 18.1 1.4 0.0025 17.9 0.4 1.6 2 0 0 2 2 2 1 Transposase Phage_Gp111 PF07410.11 ETZ04620.1 - 0.013 16.0 0.4 0.1 13.1 0.4 2.0 1 1 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein HTH_33 PF13592.6 ETZ04620.1 - 0.11 12.2 1.3 0.24 11.1 0.3 2.0 2 0 0 2 2 2 0 Winged helix-turn helix FtsK_SpoIIIE PF01580.18 ETZ04621.1 - 2e-60 204.2 0.1 3.4e-60 203.4 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_gamma PF09397.10 ETZ04621.1 - 9.5e-28 95.8 0.7 2.8e-27 94.3 0.7 1.9 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_alpha PF17854.1 ETZ04621.1 - 4.8e-26 90.9 0.0 9.5e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_4TM PF13491.6 ETZ04621.1 - 2e-16 60.2 18.9 3.6e-16 59.3 18.9 1.4 1 1 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE DUF87 PF01935.17 ETZ04621.1 - 2.5e-05 24.5 0.1 6.2e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 ETZ04621.1 - 2.6e-05 23.3 0.0 0.042 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.6 ETZ04621.1 - 0.0092 16.3 0.3 0.041 14.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ETZ04621.1 - 0.018 15.4 0.0 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 ETZ04621.1 - 0.026 14.0 3.4 7.7 5.9 0.0 3.9 4 0 0 4 4 4 0 Bacterial TniB protein EAP30 PF04157.16 ETZ04621.1 - 0.093 12.0 0.1 0.19 11.0 0.1 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family DUF350 PF03994.14 ETZ04621.1 - 9.5 6.5 8.0 0.25 11.5 0.9 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Ribosomal_L28 PF00830.19 ETZ04622.1 - 1.2e-17 63.8 0.9 1.2e-17 63.8 0.9 1.9 2 1 0 2 2 2 1 Ribosomal L28 family AA_kinase PF00696.28 ETZ04623.1 - 5.5e-20 72.0 0.0 9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family EF_TS PF00889.19 ETZ04624.1 - 3.5e-54 183.6 0.0 4.7e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor TS Atypical_Card PF18461.1 ETZ04624.1 - 0.0074 16.5 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Atypical caspase recruitment domain UBA PF00627.31 ETZ04624.1 - 0.026 14.4 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain GerD PF17898.1 ETZ04624.1 - 0.094 12.7 0.9 2.6 8.0 0.2 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain Ribosomal_S2 PF00318.20 ETZ04625.1 - 8.1e-82 273.6 0.0 9.7e-82 273.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ABC_tran_CTD PF16326.5 ETZ04625.1 - 0.044 14.0 0.6 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain HTH_38 PF13936.6 ETZ04626.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ETZ04626.1 - 0.041 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 ETZ04626.1 - 0.056 13.2 0.2 0.11 12.3 0.2 1.7 1 1 0 1 1 1 0 helix-turn-helix, Psq domain HTH_6 PF01418.17 ETZ04626.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family ABC_tran PF00005.27 ETZ04627.1 - 1.2e-28 100.3 0.0 2e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ04627.1 - 3.7e-16 59.6 5.4 6e-16 58.9 5.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ04627.1 - 1.7e-06 27.7 0.0 7.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ04627.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PsbX PF06596.11 ETZ04627.1 - 0.1 12.6 0.2 0.56 10.2 0.2 2.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) MMR_HSR1 PF01926.23 ETZ04627.1 - 0.15 12.2 0.1 0.51 10.4 0.0 1.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Peptidase_S78_2 PF14550.6 ETZ04627.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative phage serine protease XkdF DUF5563 PF17718.1 ETZ04630.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Phage_capsid PF05065.13 ETZ04631.1 - 1.1e-35 123.3 0.0 1.5e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Phage capsid family DUF16 PF01519.16 ETZ04631.1 - 0.055 14.0 0.4 0.13 12.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Peptidase_S78 PF04586.17 ETZ04632.1 - 2.5e-20 73.3 0.0 3.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Caudovirus prohead serine protease Phage_portal PF04860.12 ETZ04633.1 - 3.7e-71 239.9 0.0 4.2e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein UPF0102 PF02021.17 ETZ04635.1 - 4.2e-12 46.1 0.1 5.4e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 ETZ04635.1 - 0.00019 21.8 0.0 0.00024 21.6 0.0 1.2 1 0 0 1 1 1 1 Nuclease-related domain NucS PF01939.16 ETZ04635.1 - 0.00076 18.9 0.0 0.00095 18.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease NucS DUF4143 PF13635.6 ETZ04635.1 - 0.012 15.7 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) DUF3971 PF13116.6 ETZ04636.1 - 1.1e-10 41.6 0.5 1.1e-10 41.6 0.5 2.1 3 0 0 3 3 3 1 Protein of unknown function AsmA_1 PF13109.6 ETZ04636.1 - 1.7e-07 30.9 0.2 1.7e-07 30.9 0.2 3.5 4 0 0 4 4 4 2 AsmA-like C-terminal region AsmA_2 PF13502.6 ETZ04636.1 - 0.0017 18.0 0.1 0.0073 15.9 0.0 2.2 1 1 1 2 2 2 1 AsmA-like C-terminal region Cut8 PF08559.10 ETZ04636.1 - 0.008 15.8 0.2 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein NAD_Gly3P_dh_C PF07479.14 ETZ04637.1 - 8.1e-19 68.3 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ETZ04637.1 - 1.1e-16 61.2 0.1 2.7e-14 53.4 0.1 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 ETZ04637.1 - 0.015 15.8 0.0 0.033 14.8 0.0 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 ETZ04639.1 - 4e-18 65.8 0.0 9.1e-18 64.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETZ04639.1 - 2.7e-05 23.6 0.9 0.0052 16.1 0.8 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETZ04639.1 - 3.3e-05 23.7 0.6 5.1e-05 23.0 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETZ04639.1 - 0.00011 21.5 0.5 0.00018 20.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETZ04639.1 - 0.00095 19.4 1.4 0.0025 18.0 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETZ04639.1 - 0.0057 15.7 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 ETZ04639.1 - 0.0065 15.2 0.6 0.034 12.9 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 ETZ04639.1 - 0.012 14.5 0.1 0.68 8.7 0.2 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Fusion_gly_K PF01621.17 ETZ04639.1 - 0.026 13.6 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Cell fusion glycoprotein K Pyr_redox_2 PF07992.14 ETZ04639.1 - 0.055 12.7 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETZ04639.1 - 0.059 12.4 0.3 0.23 10.5 0.3 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 ETZ04639.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 ETZ04639.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DDE_3 PF13358.6 ETZ04641.1 - 3.7e-10 39.7 0.0 4.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease OMP_b-brl PF13505.6 ETZ04642.1 - 1.1e-05 25.7 0.0 0.00094 19.3 0.0 2.3 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ04642.1 - 0.00023 20.9 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 OmpA-like transmembrane domain SBP_bac_3 PF00497.20 ETZ04643.1 - 7.6e-46 156.3 0.0 8.6e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ETZ04643.1 - 5.8e-08 32.9 0.2 5.9e-06 26.5 0.2 2.2 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site BPD_transp_1 PF00528.22 ETZ04644.1 - 3.8e-19 69.1 5.0 5.2e-19 68.7 5.0 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 ETZ04645.1 - 1.9e-28 99.7 0.0 3.1e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ04645.1 - 5e-13 49.5 0.1 4e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ04645.1 - 1.1e-06 28.3 0.2 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ETZ04645.1 - 0.0018 18.2 0.1 0.0058 16.6 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ETZ04645.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ETZ04645.1 - 0.0078 16.6 0.1 0.018 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ETZ04645.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ETZ04645.1 - 0.03 13.1 0.3 5.6 5.6 0.0 2.9 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 ETZ04645.1 - 0.032 14.8 0.6 0.23 12.0 0.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ETZ04645.1 - 0.041 14.4 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETZ04645.1 - 0.063 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.12 ETZ04645.1 - 0.079 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 ETZ04645.1 - 0.11 12.2 0.6 0.21 11.3 0.1 1.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DHHA1 PF02272.19 ETZ04646.1 - 1.1e-14 55.0 0.0 2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 ETZ04646.1 - 4.2e-13 49.5 0.0 8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 ETZ04646.1 - 3.5e-10 40.0 0.0 6.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 DHH family Toprim PF01751.22 ETZ04646.1 - 0.12 12.7 0.0 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 Toprim domain DeoRC PF00455.22 ETZ04646.1 - 0.12 12.3 0.1 20 5.1 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain PilO PF04350.13 ETZ04646.1 - 1.7 8.8 3.7 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilO Glycos_transf_1 PF00534.20 ETZ04647.1 - 1.8e-27 95.9 0.0 4.7e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ04647.1 - 4.1e-23 82.3 0.0 6.6e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ETZ04647.1 - 9.7e-09 35.4 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ETZ04647.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DDE_Tnp_1 PF01609.21 ETZ04648.1 - 0.00033 20.4 0.0 0.00034 20.3 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ETZ04648.1 - 0.038 14.0 0.0 0.04 13.9 0.0 1.0 1 0 0 1 1 1 0 Transposase DDE domain OMP_b-brl PF13505.6 ETZ04650.1 - 0.00016 21.9 0.4 0.0066 16.6 0.0 2.6 2 1 0 2 2 2 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ04650.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 OmpA-like transmembrane domain OMP_b-brl PF13505.6 ETZ04651.1 - 1e-05 25.7 0.6 0.0077 16.4 0.0 2.9 2 1 0 2 2 2 2 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ04651.1 - 0.0011 18.7 0.0 0.0034 17.2 0.0 1.7 1 1 0 2 2 2 1 OmpA-like transmembrane domain HTH_23 PF13384.6 ETZ04653.1 - 2.5e-05 23.9 0.3 4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ04653.1 - 5e-05 23.3 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 ETZ04653.1 - 9.7e-05 22.1 0.3 0.001 18.8 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 ETZ04653.1 - 0.0002 21.3 0.1 0.00041 20.3 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix GerE PF00196.19 ETZ04653.1 - 0.0063 16.0 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family DUF1670 PF07900.11 ETZ04653.1 - 0.0094 15.3 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1670) Sigma70_r4_2 PF08281.12 ETZ04653.1 - 0.016 14.8 0.1 0.03 14.0 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 ETZ04653.1 - 0.025 14.2 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 ETZ04653.1 - 0.062 13.8 0.2 0.11 13.0 0.2 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2285 PF10074.9 ETZ04653.1 - 0.066 13.9 0.1 0.078 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) tRNA_m1G_MT PF01746.21 ETZ04656.1 - 1.1e-43 149.3 0.0 1.3e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Elong-fact-P_C PF09285.11 ETZ04657.1 - 6.5e-21 73.8 0.0 1.6e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 ETZ04657.1 - 4.3e-19 68.3 1.2 6.4e-19 67.7 0.0 2.0 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 ETZ04657.1 - 5.7e-14 51.9 0.2 9.6e-14 51.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain ATP_bind_3 PF01171.20 ETZ04658.1 - 4.7e-40 137.3 0.0 7e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 ETZ04658.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 NAD synthase dUTPase PF00692.19 ETZ04659.1 - 6.7e-28 96.9 0.0 7.9e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase ABC_tran PF00005.27 ETZ04661.1 - 9.1e-35 120.1 0.1 1.4e-34 119.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ04661.1 - 4.1e-13 49.6 28.5 5.6e-13 49.2 28.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ04661.1 - 3.4e-06 26.7 0.0 9.9e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETZ04661.1 - 0.03 14.0 0.2 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.20 ETZ04661.1 - 0.035 13.3 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 ETZ04661.1 - 0.04 14.0 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ04661.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 ETZ04661.1 - 0.056 13.4 0.1 0.89 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 ETZ04661.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain LIP PF03583.14 ETZ04661.1 - 0.16 11.2 1.5 2 7.7 0.3 2.4 1 1 1 2 2 2 0 Secretory lipase TrkA_N PF02254.18 ETZ04663.1 - 1.5e-21 76.8 0.0 2.6e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 ETZ04663.1 - 3.2e-07 30.1 0.0 0.00046 20.0 0.0 2.8 3 0 0 3 3 3 2 TrkA-C domain Thioredoxin_13 PF18401.1 ETZ04663.1 - 0.012 15.5 0.0 0.046 13.6 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_M48 PF01435.18 ETZ04664.1 - 4.9e-21 75.4 0.0 8.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 TPR_2 PF07719.17 ETZ04664.1 - 2.6e-06 27.1 1.6 0.24 11.6 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETZ04664.1 - 0.00017 22.0 0.6 0.068 13.7 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ04664.1 - 0.0019 18.8 0.2 0.072 13.8 0.0 3.1 4 1 0 4 4 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETZ04664.1 - 0.002 18.4 0.8 0.048 14.0 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETZ04664.1 - 0.0021 17.5 0.7 1.4 8.3 0.1 2.4 2 0 0 2 2 2 2 MalT-like TPR region TPR_15 PF13429.6 ETZ04664.1 - 0.0033 16.7 0.1 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETZ04664.1 - 0.0043 17.7 0.1 1.7 9.7 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETZ04664.1 - 0.0087 15.8 3.0 2.9 7.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETZ04664.1 - 0.013 15.6 1.1 1.3 9.4 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 ETZ04664.1 - 0.035 13.0 0.1 6.4 5.6 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 ETZ04664.1 - 0.16 12.2 0.0 0.56 10.5 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ETZ04664.1 - 0.17 11.6 0.0 27 4.6 0.0 3.1 3 0 0 3 3 3 0 TPR repeat EamA PF00892.20 ETZ04665.1 - 9.6e-11 42.0 35.2 1.6e-06 28.3 12.2 2.8 2 2 0 2 2 2 2 EamA-like transporter family Ribosomal_L9_C PF03948.14 ETZ04666.1 - 2.9e-15 56.5 4.4 3.6e-15 56.2 0.3 2.9 3 1 0 3 3 3 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 ETZ04666.1 - 7e-15 54.3 0.1 1.2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain YbhQ PF11076.8 ETZ04667.1 - 0.16 12.0 4.3 0.11 12.6 2.6 1.6 1 1 0 1 1 1 0 Putative inner membrane protein YbhQ Polysacc_synt_C PF14667.6 ETZ04667.1 - 2.3 8.3 22.6 2.9 7.9 9.0 3.6 1 1 2 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Ribosomal_S18 PF01084.20 ETZ04668.1 - 1.5e-10 41.1 0.8 0.00046 20.4 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S18 Ribosomal_S6 PF01250.17 ETZ04669.1 - 3.8e-18 65.5 0.0 6.1e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 ParBc PF02195.18 ETZ04670.1 - 2.5e-25 88.6 0.3 5.7e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 ETZ04670.1 - 4.5e-12 45.6 0.4 4.5e-12 45.6 0.4 2.5 3 0 0 3 3 3 1 HTH domain found in ParB protein HTH_3 PF01381.22 ETZ04670.1 - 0.0053 16.8 0.1 0.051 13.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix SoPB_HTH PF18090.1 ETZ04670.1 - 0.17 12.1 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Centromere-binding protein HTH domain Hydantoinase_B PF02538.14 ETZ04670.1 - 0.25 9.7 0.0 0.35 9.2 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Maf PF02545.14 ETZ04671.1 - 1.4e-05 25.0 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein NusG PF02357.19 ETZ04672.1 - 2.7e-13 50.2 0.0 6.9e-13 48.9 0.0 1.6 1 1 1 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 ETZ04672.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 KOW motif CodY PF06018.14 ETZ04673.1 - 0.19 11.2 2.4 0.42 10.1 0.4 2.2 2 0 0 2 2 2 0 CodY GAF-like domain DUF3484 PF11983.8 ETZ04673.1 - 0.19 12.9 1.2 15 6.8 0.3 2.7 2 1 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch DUF1798 PF08807.10 ETZ04673.1 - 1.5 9.0 12.0 0.11 12.7 0.9 3.1 3 1 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) ACPS PF01648.20 ETZ04675.1 - 2.7e-21 75.8 0.0 3.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PGM_PMM_I PF02878.16 ETZ04676.1 - 4.2e-31 107.5 0.0 8.1e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ETZ04676.1 - 5.6e-20 71.7 0.1 1e-19 70.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ETZ04676.1 - 1.2e-12 48.4 0.0 5.1e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ETZ04676.1 - 0.0017 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNA_pol_Rpb1_1 PF04997.12 ETZ04677.1 - 2.6e-83 280.0 0.0 4.2e-83 279.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ETZ04677.1 - 3.9e-62 210.1 0.1 6.2e-62 209.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ETZ04677.1 - 1.3e-38 132.8 0.0 1.6e-27 96.7 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ETZ04677.1 - 9.5e-21 74.4 0.0 2.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ETZ04677.1 - 2.1e-11 43.7 0.0 5.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Biotin_lipoyl_2 PF13533.6 ETZ04677.1 - 8.3e-09 35.1 0.8 0.21 11.4 0.1 3.6 3 0 0 3 3 3 3 Biotin-lipoyl like Apocytochr_F_C PF01333.19 ETZ04677.1 - 0.00076 19.5 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 Apocytochrome F, C-terminal Peptidase_M23 PF01551.22 ETZ04677.1 - 0.022 14.9 1.5 30 4.9 0.1 4.4 5 1 0 5 5 5 0 Peptidase family M23 RnfC_N PF13375.6 ETZ04677.1 - 0.13 12.2 0.1 8.6 6.4 0.0 2.9 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain OxoDH_E1alpha_N PF12573.8 ETZ04677.1 - 0.15 11.8 0.2 0.46 10.3 0.2 1.8 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal YqfD PF06898.11 ETZ04677.1 - 0.21 10.4 0.6 1.4 7.7 0.0 2.4 3 0 0 3 3 3 0 Putative stage IV sporulation protein YqfD RNA_pol_Rpb2_6 PF00562.28 ETZ04678.1 - 3.2e-149 497.3 0.1 5.1e-148 493.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 ETZ04678.1 - 2e-28 98.4 0.0 9.2e-28 96.2 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 ETZ04678.1 - 9.9e-24 84.0 0.0 4.1e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ETZ04678.1 - 4.8e-22 78.2 0.1 1.3e-21 76.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ETZ04678.1 - 1.5e-21 76.9 0.0 1.2e-15 57.7 0.0 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.9 ETZ04678.1 - 2.7e-15 56.4 2.5 6.2e-15 55.2 1.2 2.4 3 0 0 3 3 3 1 RNA polymerase beta subunit external 1 domain Ribosomal_L12 PF00542.19 ETZ04679.1 - 1.1e-20 73.7 4.9 2.4e-20 72.6 4.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ETZ04679.1 - 1.2e-15 57.0 2.3 1.2e-15 57.0 2.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_L10 PF00466.20 ETZ04680.1 - 2.8e-15 56.3 0.0 3.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L1 PF00687.21 ETZ04681.1 - 8.7e-41 139.9 0.0 1.1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Phenol_hyd_sub PF06099.11 ETZ04681.1 - 0.0093 16.0 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase subunit Ribosomal_L11_N PF03946.14 ETZ04682.1 - 3.4e-26 90.9 0.2 5.4e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ETZ04682.1 - 6.2e-19 68.3 0.2 1e-18 67.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NusG PF02357.19 ETZ04683.1 - 2.1e-16 60.2 0.0 3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 ETZ04683.1 - 0.02 14.8 0.0 0.066 13.2 0.0 1.9 1 0 0 1 1 1 0 KOW motif SecE PF00584.20 ETZ04684.1 - 2.7e-10 40.0 3.8 3.2e-10 39.8 3.8 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex KAP PF05804.12 ETZ04684.1 - 0.0034 15.6 0.1 0.0037 15.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) SecG PF03840.14 ETZ04685.1 - 1e-10 41.5 6.0 1.3e-10 41.2 6.0 1.1 1 0 0 1 1 1 1 Preprotein translocase SecG subunit EIID-AGA PF03613.14 ETZ04685.1 - 0.019 14.2 0.5 0.02 14.1 0.5 1.1 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component GPDPase_memb PF10110.9 ETZ04685.1 - 0.021 13.6 0.2 0.022 13.5 0.2 1.0 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Prok_Ub PF14454.6 ETZ04686.1 - 0.052 13.2 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic Ubiquitin Focal_AT PF03623.13 ETZ04686.1 - 0.054 13.5 0.5 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Focal adhesion targeting region TsaE PF02367.17 ETZ04688.1 - 1.2e-29 102.8 0.0 1.6e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ETZ04688.1 - 2.3e-05 24.8 0.0 2.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ETZ04688.1 - 5.6e-05 22.7 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 ETZ04688.1 - 0.0017 18.5 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 ETZ04688.1 - 0.0021 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 ETZ04688.1 - 0.0026 18.2 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ETZ04688.1 - 0.0032 17.4 0.1 0.0098 15.8 0.0 1.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ETZ04688.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.26 ETZ04688.1 - 0.0084 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 ETZ04688.1 - 0.027 14.2 0.0 0.072 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ETZ04688.1 - 0.043 13.1 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Septin Viral_helicase1 PF01443.18 ETZ04688.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 ETZ04688.1 - 0.052 13.8 0.1 0.074 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETZ04688.1 - 0.065 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 ETZ04688.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 ETZ04688.1 - 0.1 12.0 0.3 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein Bac_DnaA PF00308.18 ETZ04688.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_5 PF07728.14 ETZ04688.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 ETZ04688.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase HHH_5 PF14520.6 ETZ04689.1 - 2.4e-14 53.7 0.5 1.7e-13 50.9 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain RuvA_N PF01330.21 ETZ04689.1 - 3.1e-13 49.6 1.6 3.3e-12 46.3 0.5 2.5 3 0 0 3 3 3 1 RuvA N terminal domain HHH PF00633.23 ETZ04689.1 - 1.7e-07 30.7 0.4 0.001 18.8 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif RuvA_C PF07499.13 ETZ04689.1 - 8.1e-07 29.4 0.4 1.8e-06 28.3 0.4 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH_2 PF12826.7 ETZ04689.1 - 1.5e-06 28.2 0.2 0.0044 17.1 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 ETZ04689.1 - 9.5e-05 22.9 0.0 0.0029 18.2 0.0 2.3 1 1 1 2 2 2 2 5'-3' exonuclease, C-terminal SAM fold HHH_3 PF12836.7 ETZ04689.1 - 0.0001 22.5 0.0 0.57 10.5 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 ETZ04689.1 - 0.00012 22.4 0.0 0.44 11.0 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain DUF3701 PF12482.8 ETZ04689.1 - 0.00086 19.3 0.0 0.29 11.2 0.0 2.6 1 1 1 2 2 2 2 Phage integrase protein Transposase_20 PF02371.16 ETZ04689.1 - 0.0013 18.9 0.0 3.3 8.1 0.0 3.0 3 0 0 3 3 3 2 Transposase IS116/IS110/IS902 family Cdd1 PF11731.8 ETZ04689.1 - 0.0046 17.2 0.0 1.5 9.1 0.0 2.5 2 1 0 2 2 2 1 Pathogenicity locus IMS_HHH PF11798.8 ETZ04689.1 - 0.0088 16.3 0.1 6.1 7.4 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif Thymidylate_kin PF02223.17 ETZ04690.1 - 3.1e-41 141.1 0.0 3.5e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 ETZ04690.1 - 8.1e-05 22.9 0.0 9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETZ04690.1 - 0.037 14.3 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Peptidase_S11 PF00768.20 ETZ04691.1 - 6.9e-53 179.6 0.0 8.7e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 ETZ04691.1 - 2e-10 40.8 0.6 3.5e-10 40.0 0.6 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 ETZ04691.1 - 1.9e-08 34.2 0.0 2.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 ETZ04691.1 - 0.021 13.6 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family NES_C_h PF18208.1 ETZ04691.1 - 0.11 12.8 0.1 3 8.2 0.0 2.6 3 0 0 3 3 3 0 Nicking enzyme C-terminal middle helical domain DPBB_1 PF03330.18 ETZ04692.1 - 1.3e-20 73.4 0.0 2.7e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase SPOR PF05036.13 ETZ04692.1 - 0.0025 18.1 0.0 0.0088 16.4 0.0 2.0 1 1 0 1 1 1 1 Sporulation related domain Transcrip_reg PF01709.20 ETZ04693.1 - 5.3e-73 245.4 0.2 6e-73 245.2 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator AA_permease_2 PF13520.6 ETZ04694.1 - 1.3e-22 80.2 54.1 1.6e-22 79.9 54.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETZ04694.1 - 7.2e-06 24.9 40.1 0.00016 20.4 40.0 2.5 1 1 0 1 1 1 1 Amino acid permease PMP1_2 PF08114.11 ETZ04694.1 - 1.8 8.4 6.6 0.34 10.7 2.0 2.2 2 0 0 2 2 2 0 ATPase proteolipid family S1FA PF04689.13 ETZ04696.1 - 0.0019 18.3 0.1 0.0058 16.8 0.1 1.8 1 0 0 1 1 1 1 DNA binding protein S1FA YMF19 PF02326.15 ETZ04696.1 - 4.8 8.0 7.1 0.76 10.6 1.1 2.7 2 1 0 2 2 2 0 Plant ATP synthase F0 Transpeptidase PF00905.22 ETZ04697.1 - 2.1e-36 125.7 0.0 2.6e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 ETZ04697.1 - 7.8e-08 32.9 0.0 2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MnmE_helical PF12631.7 ETZ04698.1 - 0.024 14.8 1.3 0.024 14.8 1.3 2.4 1 1 0 2 2 2 0 MnmE helical domain NPV_P10 PF05531.12 ETZ04698.1 - 0.053 14.0 1.4 0.17 12.4 1.4 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 ETZ04698.1 - 0.62 10.2 5.0 1.9 8.6 1.2 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase PSP1 PF04468.12 ETZ04698.1 - 0.72 10.2 9.3 0.35 11.2 3.0 2.5 2 1 0 2 2 2 0 PSP1 C-terminal conserved region DASH_Duo1 PF08651.10 ETZ04698.1 - 0.8 9.5 11.4 0.88 9.4 1.7 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 APG6_N PF17675.1 ETZ04698.1 - 0.8 10.2 23.1 0.053 14.1 10.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Fra10Ac1 PF09725.9 ETZ04698.1 - 2 8.5 11.7 0.2 11.7 0.8 2.8 1 1 1 3 3 3 0 Folate-sensitive fragile site protein Fra10Ac1 ABC_tran_CTD PF16326.5 ETZ04698.1 - 2.2 8.6 14.4 0.38 11.0 4.9 2.9 2 2 0 2 2 2 0 ABC transporter C-terminal domain TMPIT PF07851.13 ETZ04698.1 - 4.5 6.4 16.6 0.61 9.3 6.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 ETZ04698.1 - 4.9 6.8 6.9 2.2 8.0 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF5320 PF17253.2 ETZ04698.1 - 8.1 7.6 17.6 0.84 10.7 0.3 3.6 2 2 1 3 3 3 0 Family of unknown function (DUF5320) Rx_N PF18052.1 ETZ04698.1 - 8.7 6.7 11.3 21 5.5 2.2 3.4 2 2 1 3 3 3 0 Rx N-terminal domain Exonuc_VII_L PF02601.15 ETZ04698.1 - 9.7 5.7 14.1 18 4.8 14.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit RBFA PF02033.18 ETZ04699.1 - 1e-14 54.8 1.0 1.2e-14 54.6 1.0 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A SCP2 PF02036.17 ETZ04699.1 - 0.017 15.6 0.0 0.021 15.3 0.0 1.1 1 0 0 1 1 1 0 SCP-2 sterol transfer family MFS_1 PF07690.16 ETZ04700.1 - 2e-30 105.9 43.8 2e-30 105.9 43.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Prenyltransf PF01255.19 ETZ04701.1 - 8e-73 244.7 0.0 9e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DNA_pol3_delta2 PF13177.6 ETZ04702.1 - 1.8e-34 118.9 0.0 3.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 ETZ04702.1 - 1.9e-22 79.7 1.7 1.9e-22 79.7 0.2 1.9 2 0 0 2 2 1 1 DNA polymerase III subunits gamma and tau domain III AAA PF00004.29 ETZ04702.1 - 7.3e-12 45.8 0.0 2.2e-11 44.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF3646 PF12362.8 ETZ04702.1 - 4.2e-08 33.5 0.7 8.5e-08 32.5 0.4 1.7 2 0 0 2 2 1 1 DNA polymerase III gamma and tau subunits C terminal AAA_22 PF13401.6 ETZ04702.1 - 1.1e-07 32.2 0.1 7.7e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETZ04702.1 - 1.9e-06 27.9 1.5 0.049 13.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ04702.1 - 4.5e-06 27.1 1.2 4.4e-05 23.9 0.1 3.0 3 2 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 ETZ04702.1 - 4.9e-06 26.4 0.0 0.00056 19.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ETZ04702.1 - 0.00023 21.2 0.2 0.0028 17.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETZ04702.1 - 0.00035 20.4 0.0 0.0012 18.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 ETZ04702.1 - 0.00087 18.6 0.1 0.94 8.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 ETZ04702.1 - 0.00093 19.2 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 ETZ04702.1 - 0.0013 19.1 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETZ04702.1 - 0.0022 18.5 0.1 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 ETZ04702.1 - 0.0033 17.2 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 ETZ04702.1 - 0.0034 17.1 0.0 0.01 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 ETZ04702.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_assoc_2 PF16193.5 ETZ04702.1 - 0.014 15.7 0.0 0.051 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain Sigma54_activat PF00158.26 ETZ04702.1 - 0.015 15.0 0.0 0.052 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ETZ04702.1 - 0.022 14.8 0.1 2.2 8.4 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 ETZ04702.1 - 0.03 14.2 0.3 0.1 12.5 0.4 1.8 2 0 0 2 2 2 0 NTPase ResIII PF04851.15 ETZ04702.1 - 0.033 14.2 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 ETZ04702.1 - 0.062 13.7 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 ETZ04702.1 - 0.089 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 ETZ04702.1 - 0.099 12.9 3.4 0.31 11.3 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETZ04702.1 - 0.14 12.3 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ETZ04702.1 - 0.15 11.9 0.1 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase K-box PF01486.17 ETZ04703.1 - 0.33 11.1 9.0 0.028 14.6 3.4 2.1 3 0 0 3 3 3 0 K-box region DegT_DnrJ_EryC1 PF01041.17 ETZ04704.1 - 2.3e-109 366.0 0.0 2.6e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ETZ04704.1 - 2.6e-10 40.0 0.0 3.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ETZ04704.1 - 0.00092 18.6 0.0 0.0048 16.2 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ETZ04704.1 - 0.0016 17.5 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 ETZ04704.1 - 0.13 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain FtsJ PF01728.19 ETZ04705.1 - 4.5e-44 150.7 0.0 5.2e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ETZ04705.1 - 6.3e-05 22.9 0.0 0.00038 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04705.1 - 0.00087 19.1 0.0 0.04 13.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETZ04705.1 - 0.0082 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 ETZ04705.1 - 0.013 16.2 0.3 0.063 14.0 0.3 2.1 1 1 0 1 1 1 0 Methyltransferase domain MMR_HSR1 PF01926.23 ETZ04706.1 - 5.3e-40 136.0 0.0 8.6e-23 80.6 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 ETZ04706.1 - 4.8e-24 84.5 0.1 1e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 ETZ04706.1 - 2.9e-17 62.6 0.0 3.5e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 ETZ04706.1 - 5.5e-12 45.6 0.0 0.0015 18.1 0.0 5.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ETZ04706.1 - 4.4e-09 36.6 0.0 0.0041 17.2 0.0 3.3 3 0 0 3 3 3 2 Dynamin family ABC_tran PF00005.27 ETZ04706.1 - 3.6e-07 30.8 0.1 0.0045 17.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 ETZ04706.1 - 1.1e-06 28.7 0.1 0.081 12.8 0.0 3.8 4 0 0 4 4 4 2 RsgA GTPase AIG1 PF04548.16 ETZ04706.1 - 3.6e-06 26.4 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 2 AIG1 family Arf PF00025.21 ETZ04706.1 - 0.00077 19.0 0.0 0.48 9.9 0.0 3.1 2 2 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 ETZ04706.1 - 0.00085 19.1 0.0 0.022 14.5 0.0 3.0 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ETZ04706.1 - 0.0013 18.4 0.9 1.2 8.9 0.0 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain Roc PF08477.13 ETZ04706.1 - 0.0013 18.9 0.1 0.092 13.0 0.1 3.1 2 2 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ETZ04706.1 - 0.0022 17.4 0.1 0.016 14.6 0.0 2.2 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Septin PF00735.18 ETZ04706.1 - 0.0086 15.4 0.1 0.42 9.8 0.0 2.6 2 1 0 2 2 2 1 Septin NB-ARC PF00931.22 ETZ04706.1 - 0.02 14.1 0.0 0.084 12.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 ETZ04706.1 - 0.022 14.5 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 ETZ04706.1 - 0.053 13.0 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 ETZ04706.1 - 0.087 12.2 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 ETZ04706.1 - 0.12 12.3 0.1 7 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 ETZ04706.1 - 0.13 12.0 0.2 45 3.7 0.1 3.3 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein Ras PF00071.22 ETZ04706.1 - 0.15 11.7 0.1 1.3 8.6 0.0 2.5 2 1 0 2 2 2 0 Ras family MeaB PF03308.16 ETZ04706.1 - 0.17 10.8 0.8 9.8 5.1 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 ETZ04706.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PQQ_2 PF13360.6 ETZ04707.1 - 8.5e-31 107.4 0.0 1.3e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 ETZ04707.1 - 5e-12 45.1 0.1 0.00045 20.0 0.0 5.2 5 0 0 5 5 5 3 PQQ enzyme repeat PQQ_3 PF13570.6 ETZ04707.1 - 2.2e-11 43.9 7.5 0.00029 21.2 0.6 5.9 5 1 0 5 5 5 2 PQQ-like domain KBP_C PF12309.8 ETZ04708.1 - 0.0034 17.0 2.4 0.0034 17.0 2.4 1.7 2 1 0 2 2 2 1 KIF-1 binding protein C terminal TPR_21 PF09976.9 ETZ04708.1 - 0.013 15.2 1.6 0.053 13.2 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Halogen_Hydrol PF10112.9 ETZ04708.1 - 0.033 14.2 0.2 0.033 14.2 0.2 1.6 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ArnB_C PF18677.1 ETZ04708.1 - 0.071 13.2 1.7 1.8 8.7 0.4 2.5 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain ATP_bind_2 PF03668.15 ETZ04709.1 - 3.6e-74 249.6 0.0 4.1e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_22 PF13401.6 ETZ04709.1 - 0.0027 18.0 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETZ04709.1 - 0.036 14.6 0.6 0.44 11.1 0.6 2.2 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETZ04709.1 - 0.036 13.3 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 ETZ04709.1 - 0.041 14.0 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 ETZ04709.1 - 0.075 13.2 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Shikimate kinase ROS_MUCR PF05443.11 ETZ04710.1 - 9.8e-40 135.5 0.0 1.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein DUF1013 PF06242.11 ETZ04711.1 - 1.6e-36 125.4 0.0 3.2e-36 124.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1013) LpxK PF02606.14 ETZ04712.1 - 2e-62 211.2 0.0 2.7e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase UvrD-helicase PF00580.21 ETZ04713.1 - 2.2e-67 227.8 8.8 1e-65 222.4 5.5 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ETZ04713.1 - 6.8e-59 200.0 0.3 3.8e-58 197.6 0.0 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ETZ04713.1 - 1.1e-32 113.4 0.0 3.3e-32 111.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ETZ04713.1 - 2.7e-09 36.7 0.2 9.2e-09 35.0 0.2 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 ETZ04713.1 - 1.4e-06 28.2 0.2 0.0004 20.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ETZ04713.1 - 1.8e-05 24.6 0.2 0.00017 21.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 ETZ04713.1 - 0.014 14.5 0.1 0.042 12.9 0.1 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 ETZ04713.1 - 0.017 15.1 0.7 0.048 13.7 0.1 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_12 PF13087.6 ETZ04713.1 - 0.046 13.3 0.4 13 5.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ETZ04713.1 - 0.051 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 ETZ04714.1 - 1.5e-55 189.0 16.6 5.5e-32 111.5 2.5 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ETZ04714.1 - 6.1e-49 167.3 8.5 1.9e-28 99.8 1.3 2.6 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ETZ04714.1 - 4.2e-29 101.8 0.0 8.8e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ETZ04714.1 - 8.2e-08 32.0 0.1 1.1e-06 28.4 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 ETZ04714.1 - 2.5e-05 24.1 0.0 0.052 13.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ETZ04714.1 - 0.00046 20.0 0.4 0.022 14.5 0.4 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 ETZ04714.1 - 0.043 13.8 1.8 1.2 9.1 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ETZ04714.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Hydrolase_4 PF12146.8 ETZ04715.1 - 6.8e-07 28.8 0.0 2.9e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETZ04715.1 - 1.4e-05 24.9 0.0 7.1e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETZ04715.1 - 3.4e-05 23.4 0.0 0.049 13.1 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ETZ04715.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ETZ04715.1 - 0.00088 19.9 0.0 0.0032 18.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 ETZ04715.1 - 0.0056 15.7 0.0 0.0081 15.2 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 ETZ04715.1 - 0.076 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family malic PF00390.19 ETZ04716.1 - 2.1e-21 76.5 0.1 1.3e-18 67.4 0.1 2.4 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ETZ04716.1 - 7.8e-20 71.2 0.0 2.4e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain MgtE PF01769.16 ETZ04717.1 - 6.2e-24 84.7 4.6 6.2e-24 84.7 4.6 1.9 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 ETZ04717.1 - 1.7e-14 54.2 1.2 1.7e-14 54.2 1.2 1.8 2 0 0 2 2 2 1 MgtE intracellular N domain CBS PF00571.28 ETZ04717.1 - 5.4e-11 42.8 4.0 4.2e-05 23.9 1.1 2.7 3 0 0 3 3 3 2 CBS domain RNA_binding PF01877.17 ETZ04717.1 - 0.11 12.7 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 RNA binding FliG_M PF14841.6 ETZ04717.1 - 0.25 11.6 1.3 8.4 6.7 0.6 3.0 2 1 1 3 3 3 0 FliG middle domain Ribosomal_L35p PF01632.19 ETZ04718.1 - 2.2e-20 72.9 9.2 2.6e-20 72.6 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 ETZ04719.1 - 1.3e-43 147.5 2.6 1.5e-43 147.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 DUF2312 PF10073.9 ETZ04720.1 - 2.6e-22 78.2 5.5 2.9e-22 78.1 5.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) sCache_like PF16736.5 ETZ04720.1 - 0.018 15.1 0.6 0.021 14.9 0.6 1.1 1 0 0 1 1 1 0 Single Cache-like Nif11 PF07862.11 ETZ04720.1 - 0.049 13.9 0.2 0.097 13.0 0.2 1.5 1 0 0 1 1 1 0 Nif11 domain HBD PF18534.1 ETZ04720.1 - 0.062 13.4 1.8 0.16 12.1 1.8 1.7 1 1 0 1 1 1 0 Helical bundle domain Abhydrolase_2 PF02230.16 ETZ04721.1 - 6e-22 78.5 0.0 9.5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ETZ04721.1 - 0.0013 18.0 0.7 1.5 8.0 0.3 3.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 ETZ04721.1 - 0.0044 16.7 0.6 0.085 12.5 0.6 2.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ETZ04721.1 - 0.0056 17.3 0.0 0.0076 16.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETZ04721.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LptF_LptG PF03739.14 ETZ04722.1 - 3.6e-29 101.7 2.5 4.2e-29 101.5 2.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG LptF_LptG PF03739.14 ETZ04723.1 - 8.4e-11 41.3 23.5 4.4e-10 38.9 23.5 2.0 1 1 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG LpxB PF02684.15 ETZ04724.1 - 1.5e-85 287.4 0.0 1.8e-85 287.1 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase DUF354 PF04007.12 ETZ04724.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF354) PNTB_4TM PF12769.7 ETZ04725.1 - 4.7e-17 62.2 4.0 4.7e-17 62.2 4.0 1.6 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF1077 PF06417.12 ETZ04725.1 - 0.63 10.1 4.6 5.3 7.1 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) AlaDh_PNT_C PF01262.21 ETZ04726.1 - 3.9e-45 153.8 0.0 5.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ETZ04726.1 - 3.1e-16 59.9 0.0 4.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ETZ04726.1 - 0.034 13.5 0.1 0.26 10.6 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 ETZ04726.1 - 0.041 14.4 0.0 0.58 10.7 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain ADH_zinc_N PF00107.26 ETZ04726.1 - 0.24 11.4 1.0 2.4 8.1 0.2 2.6 3 1 0 3 3 3 0 Zinc-binding dehydrogenase MutS_V PF00488.21 ETZ04727.1 - 0.052 13.6 0.0 0.052 13.6 0.0 1.0 1 0 0 1 1 1 0 MutS domain V APH_6_hur PF04655.14 ETZ04729.1 - 3.6e-13 49.5 0.1 5e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 ETZ04729.1 - 4.5e-06 26.8 0.1 5.5e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ETZ04729.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Dynein_heavy PF03028.15 ETZ04729.1 - 0.017 15.2 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain DUF3991 PF13154.6 ETZ04729.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) DUF2975 PF11188.8 ETZ04730.1 - 5.1e-06 26.4 0.1 5.8e-06 26.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) FUSC-like PF12805.7 ETZ04730.1 - 0.3 10.1 3.3 0.25 10.4 0.3 1.9 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS HTH_26 PF13443.6 ETZ04731.1 - 0.02 15.3 0.3 0.021 15.3 0.3 1.1 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Hydrolase_4 PF12146.8 ETZ04732.1 - 0.033 13.4 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NUDIX-like PF09296.11 ETZ04732.1 - 0.13 13.0 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain Peptidase_S9 PF00326.21 ETZ04733.1 - 5.8e-05 22.7 0.1 6.4e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ETZ04733.1 - 0.0017 18.3 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 ETZ04733.1 - 0.019 14.6 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) ATR13 PF16829.5 ETZ04733.1 - 0.08 13.3 0.2 0.16 12.4 0.2 1.4 1 1 0 1 1 1 0 Avirulence protein ATR13, RxLR effector BAAT_C PF08840.11 ETZ04733.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ETZ04733.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GyrI-like PF06445.15 ETZ04734.1 - 2.2e-26 93.0 0.0 2.4e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 ETZ04734.1 - 9.1e-14 51.9 0.0 1.1e-13 51.6 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein HTH_18 PF12833.7 ETZ04735.1 - 3.5e-05 24.0 0.0 4.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ETZ04735.1 - 0.00014 21.8 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family TspO_MBR PF03073.15 ETZ04736.1 - 1.1e-38 132.3 23.2 1.3e-38 132.1 23.2 1.0 1 0 0 1 1 1 1 TspO/MBR family ASFV_J13L PF05568.11 ETZ04736.1 - 0.46 10.2 1.3 0.84 9.4 1.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Peptidase_M23 PF01551.22 ETZ04737.1 - 3.2e-32 110.6 0.7 5.5e-32 109.8 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M23 PseudoU_synth_1 PF01416.20 ETZ04738.1 - 7.1e-29 100.4 0.2 3.4e-23 82.2 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Mlo PF03094.15 ETZ04738.1 - 0.016 13.6 0.0 0.021 13.2 0.0 1.1 1 0 0 1 1 1 0 Mlo family DUF809 PF05663.11 ETZ04739.1 - 0.043 13.9 4.6 0.051 13.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF809) TRAP_alpha PF03896.16 ETZ04739.1 - 0.16 11.2 8.0 0.16 11.1 8.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit dsRBD2 PF17842.1 ETZ04739.1 - 0.17 12.0 2.3 0.2 11.8 2.3 1.1 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 V_ATPase_I PF01496.19 ETZ04739.1 - 0.19 9.6 3.9 0.2 9.5 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 ETZ04739.1 - 0.28 10.4 2.5 0.29 10.3 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 ETZ04739.1 - 0.36 10.6 3.3 0.4 10.4 3.3 1.1 1 0 0 1 1 1 0 Connexin MAP17 PF15807.5 ETZ04739.1 - 0.42 10.8 5.4 0.51 10.6 5.4 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PI3K_1B_p101 PF10486.9 ETZ04739.1 - 0.56 7.9 8.2 0.59 7.8 8.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SID-1_RNA_chan PF13965.6 ETZ04739.1 - 0.58 8.5 2.6 0.59 8.5 2.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 ETZ04739.1 - 0.65 8.9 1.6 0.66 8.9 1.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 ETZ04739.1 - 0.71 8.6 4.1 0.73 8.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 ETZ04739.1 - 0.91 8.8 11.5 0.95 8.7 11.5 1.0 1 0 0 1 1 1 0 NOA36 protein PPL5 PF18168.1 ETZ04739.1 - 1 8.6 7.3 1.1 8.5 7.3 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Serinc PF03348.15 ETZ04739.1 - 1.2 7.9 2.6 1.3 7.8 2.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Vfa1 PF08432.10 ETZ04739.1 - 1.4 9.2 15.8 1.5 9.1 15.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.16 ETZ04739.1 - 1.9 8.0 6.2 2.1 7.8 6.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Ureide_permease PF07168.11 ETZ04739.1 - 2.1 7.0 2.9 2.3 6.9 2.9 1.2 1 0 0 1 1 1 0 Ureide permease Astro_capsid_p PF12226.8 ETZ04739.1 - 3.4 6.7 11.2 3.6 6.6 11.2 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ATP-synt_C PF00137.21 ETZ04740.1 - 3.7e-08 33.6 8.3 4.4e-08 33.3 8.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit C YMF19 PF02326.15 ETZ04741.1 - 2.9e-08 34.4 0.9 5.8e-08 33.4 0.7 1.8 1 1 0 1 1 1 1 Plant ATP synthase F0 Plasmid_RAQPRD PF09686.10 ETZ04741.1 - 0.0058 16.8 3.0 0.0097 16.1 2.5 1.7 1 1 0 1 1 1 1 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1139 PF06599.11 ETZ04741.1 - 0.037 13.4 0.5 0.045 13.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) Phage_Mu_Gam PF07352.12 ETZ04741.1 - 0.055 13.4 5.6 0.39 10.6 5.5 2.0 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF883 PF05957.13 ETZ04741.1 - 0.11 13.1 4.8 0.072 13.7 1.9 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 ETZ04741.1 - 0.19 11.8 5.0 1.1 9.3 4.2 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 ETZ04741.1 - 0.19 11.8 2.8 0.29 11.2 2.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.10 ETZ04741.1 - 0.28 11.5 7.3 0.61 10.4 7.2 1.7 1 1 0 1 1 1 0 Tup N-terminal PIN_4 PF13638.6 ETZ04741.1 - 0.37 11.1 3.7 0.53 10.6 3.7 1.3 1 1 0 1 1 1 0 PIN domain NPV_P10 PF05531.12 ETZ04741.1 - 1 9.9 4.7 8.9 6.9 4.7 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LCIB_C_CA PF18599.1 ETZ04741.1 - 2.4 7.4 6.0 4.4 6.5 1.2 1.9 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4407 PF14362.6 ETZ04741.1 - 7.8 5.8 12.0 4.9 6.4 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.18 ETZ04742.1 - 0.002 18.2 0.7 0.0046 17.1 0.8 1.7 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) DUF948 PF06103.11 ETZ04742.1 - 0.028 14.7 0.1 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF445 PF04286.12 ETZ04742.1 - 0.086 12.6 4.4 0.11 12.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) OmpH PF03938.14 ETZ04742.1 - 0.57 10.5 15.4 9.4 6.6 15.4 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 ETZ04742.1 - 0.83 9.2 6.6 1 8.9 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 ETZ04742.1 - 4.1 7.1 7.7 6.2 6.5 7.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) tRNA_Me_trans PF03054.16 ETZ04743.1 - 2.5e-101 339.0 0.0 2.9e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 ETZ04743.1 - 0.00036 19.7 0.2 0.00085 18.5 0.2 1.6 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 ETZ04743.1 - 0.0006 19.4 0.2 0.0015 18.0 0.1 1.7 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 ETZ04743.1 - 0.00091 19.0 0.0 0.0019 18.0 0.0 1.5 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 ETZ04743.1 - 0.036 13.8 0.2 0.15 11.8 0.2 2.0 1 1 0 1 1 1 0 PP-loop family ThiI PF02568.14 ETZ04743.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 ETZ04743.1 - 0.055 12.7 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase DDE_Tnp_4 PF13359.6 ETZ04744.1 - 0.008 15.9 1.7 0.012 15.3 1.5 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2681 PF10883.8 ETZ04744.1 - 0.086 13.3 8.3 0.069 13.6 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) ATP-synt PF00231.19 ETZ04747.1 - 2.9e-50 171.6 1.0 3.3e-50 171.4 1.0 1.0 1 0 0 1 1 1 1 ATP synthase PriX PF18689.1 ETZ04747.1 - 0.027 14.8 0.4 0.066 13.6 0.4 1.6 1 0 0 1 1 1 0 Primase X Alpha_Helical PF18489.1 ETZ04747.1 - 0.087 13.0 1.1 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Alpha helical domain ATP-synt_ab PF00006.25 ETZ04748.1 - 2.7e-73 246.1 0.0 3.9e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ETZ04748.1 - 8.4e-43 145.7 0.6 2.7e-42 144.1 0.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ETZ04748.1 - 4.1e-14 52.8 1.2 1.4e-13 51.1 1.2 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HTH_38 PF13936.6 ETZ04749.1 - 0.00036 20.2 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ETZ04749.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 ETZ04749.1 - 0.0052 17.0 0.0 0.007 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_11 PF08279.12 ETZ04749.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 ETZ04749.1 - 0.076 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_GH3_C PF18034.1 ETZ04749.1 - 0.096 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain HTH_psq PF05225.16 ETZ04749.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_19 PF12844.7 ETZ04749.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 ETZ04749.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) SIT PF15330.6 ETZ04750.1 - 0.36 11.3 3.0 1.2 9.6 3.0 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT GTP_EFTU PF00009.27 ETZ04751.1 - 3.1e-61 206.3 0.1 4.1e-61 205.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ETZ04751.1 - 2.7e-30 104.9 0.0 5e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ETZ04751.1 - 1.7e-17 63.6 6.2 4.3e-17 62.3 6.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETZ04751.1 - 7.2e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ04751.1 - 0.0081 16.1 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 ETZ04751.1 - 0.022 14.3 0.5 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ETZ04751.1 - 0.035 13.9 0.3 9.5 6.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 ETZ04751.1 - 0.22 11.3 0.8 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_S10 PF00338.22 ETZ04752.1 - 1.3e-25 89.4 0.0 1.5e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L3 PF00297.22 ETZ04753.1 - 2.1e-17 63.1 2.1 3.6e-15 55.8 1.0 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_L4 PF00573.22 ETZ04754.1 - 2e-56 190.7 0.0 2.3e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 ETZ04755.1 - 7.3e-23 80.7 2.1 9.2e-23 80.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Spy1 PF11357.8 ETZ04755.1 - 0.047 14.0 0.1 0.06 13.6 0.1 1.2 1 0 0 1 1 1 0 Cell cycle regulatory protein Ribosomal_L2_C PF03947.18 ETZ04756.1 - 5.8e-57 191.3 0.5 9.6e-57 190.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ETZ04756.1 - 1.6e-21 76.0 0.0 4.2e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S19 PF00203.21 ETZ04757.1 - 6.1e-37 125.4 0.1 6.8e-37 125.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.19 ETZ04758.1 - 2.7e-19 69.3 0.0 3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 ETZ04759.1 - 2e-34 118.0 0.3 2.9e-34 117.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ETZ04759.1 - 1.9e-12 46.9 0.0 3.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 KH domain GerPC PF10737.9 ETZ04759.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC MRP-S24 PF14955.6 ETZ04759.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Ribosomal_L16 PF00252.18 ETZ04760.1 - 1.4e-44 151.3 0.3 1.6e-44 151.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L29 PF00831.23 ETZ04761.1 - 1.6e-06 28.0 0.5 2.2e-06 27.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S17 PF00366.20 ETZ04762.1 - 3.8e-26 91.0 1.8 4.3e-26 90.8 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 ETZ04763.1 - 5.6e-46 155.6 1.3 6.2e-46 155.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ribosomal_L24 PF17136.4 ETZ04764.1 - 2e-15 56.9 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ETZ04764.1 - 1.1e-07 31.5 0.8 2.8e-07 30.2 0.8 1.7 1 0 0 1 1 1 1 KOW motif SRR1 PF07985.12 ETZ04764.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 SRR1 Ribosomal_L5_C PF00673.21 ETZ04765.1 - 2.8e-35 120.4 0.0 4.2e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ETZ04765.1 - 3.3e-18 65.8 0.0 4.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Endosulfine PF04667.17 ETZ04765.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Ribosomal_S14 PF00253.21 ETZ04766.1 - 1.1e-23 82.7 1.1 1.1e-23 82.7 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Ribosomal_S8 PF00410.19 ETZ04767.1 - 6.1e-40 136.1 0.1 6.8e-40 135.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 YjhX_toxin PF09857.9 ETZ04767.1 - 0.14 12.1 0.7 1.8 8.6 0.1 2.4 2 1 0 2 2 2 0 Putative toxin of bacterial toxin-antitoxin pair Ribosomal_L6 PF00347.23 ETZ04768.1 - 1e-10 42.1 0.1 1.5e-08 35.1 0.1 2.7 2 1 1 3 3 3 2 Ribosomal protein L6 Ribosomal_L18p PF00861.22 ETZ04769.1 - 4.8e-40 136.5 0.8 5.3e-40 136.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L5e PF17144.4 ETZ04769.1 - 0.0075 16.3 0.2 0.0085 16.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 RraA-like PF03737.15 ETZ04769.1 - 0.035 14.3 0.1 0.051 13.7 0.1 1.4 1 1 0 1 1 1 0 Aldolase/RraA Chordopox_A33R PF05966.12 ETZ04769.1 - 0.063 12.5 0.1 0.072 12.4 0.1 1.4 1 1 0 1 1 1 0 Chordopoxvirus A33R protein Ribosomal_S5_C PF03719.15 ETZ04770.1 - 1.4e-26 91.8 0.3 2.2e-26 91.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ETZ04770.1 - 4.8e-26 90.5 5.1 1.2e-25 89.3 5.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L30 PF00327.20 ETZ04771.1 - 1.3e-12 47.4 0.5 1.4e-12 47.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 ETZ04772.1 - 2.7e-30 105.7 0.0 3.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SecY PF00344.20 ETZ04773.1 - 9.3e-85 284.6 18.0 1.2e-84 284.2 18.0 1.1 1 0 0 1 1 1 1 SecY translocase ADK PF00406.22 ETZ04774.1 - 1.7e-30 106.1 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ETZ04774.1 - 3.6e-16 59.8 0.0 1.1e-15 58.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETZ04774.1 - 4.9e-10 40.1 0.0 1.3e-09 38.7 0.0 1.6 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 ETZ04774.1 - 0.00013 21.7 1.9 0.061 13.0 0.0 3.0 1 1 1 3 3 3 2 Thymidylate kinase AAA_33 PF13671.6 ETZ04774.1 - 0.06 13.5 0.1 0.35 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ETZ04774.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Frataxin_Cyay PF01491.16 ETZ04776.1 - 1.7e-16 60.2 0.0 2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain HATPase_c PF02518.26 ETZ04777.1 - 3.8e-15 56.4 0.0 7.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETZ04777.1 - 2.3e-10 40.3 0.4 2.8e-09 36.9 0.0 3.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ETZ04777.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HAMP PF00672.25 ETZ04777.1 - 0.012 16.0 2.5 0.014 15.7 0.3 2.4 2 1 0 2 2 2 0 HAMP domain ER PF01133.17 ETZ04777.1 - 0.058 13.4 0.5 0.16 12.0 0.5 1.8 1 0 0 1 1 1 0 Enhancer of rudimentary Sigma70_r1_1 PF03979.14 ETZ04777.1 - 0.12 12.4 1.2 1.3 9.1 0.3 2.6 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF1129 PF06570.11 ETZ04777.1 - 0.14 11.7 2.7 0.18 11.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) T_Ag_DNA_bind PF02217.16 ETZ04777.1 - 0.45 11.2 3.3 2 9.1 0.4 3.0 2 1 0 2 2 2 0 Origin of replication binding protein DHHC PF01529.20 ETZ04777.1 - 0.77 9.9 4.7 1.8 8.7 0.5 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Dus PF01207.17 ETZ04778.1 - 6.9e-88 294.7 0.0 8.5e-88 294.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) LRR_4 PF12799.7 ETZ04779.1 - 2e-10 40.7 0.3 0.00034 20.9 0.0 2.9 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ETZ04779.1 - 0.017 14.7 0.1 0.06 12.9 0.0 1.9 1 1 1 2 2 2 0 Leucine-rich repeat S4_2 PF13275.6 ETZ04779.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 S4 domain S4 PF01479.25 ETZ04779.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 S4 domain TyrRSs_C PF16714.5 ETZ04779.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain DciA PF05258.12 ETZ04780.1 - 1.3e-10 41.5 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA HTH_Tnp_IS630 PF01710.16 ETZ04782.1 - 0.00023 21.2 0.0 0.00025 21.1 0.0 1.0 1 0 0 1 1 1 1 Transposase rve_2 PF13333.6 ETZ04783.1 - 4.7e-06 26.7 0.1 6.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ETZ04783.1 - 0.0003 20.5 0.1 0.00042 20.0 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain Acetyltransf_10 PF13673.7 ETZ04784.1 - 5.6e-09 36.0 0.0 6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04784.1 - 1.2e-08 35.1 0.0 1.5e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04784.1 - 5.4e-08 33.2 0.0 7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETZ04784.1 - 0.0031 17.4 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltr_2 PF13718.6 ETZ04784.1 - 0.02 14.3 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF4253 PF14062.6 ETZ04784.1 - 0.024 14.8 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) GrpB PF04229.14 ETZ04785.1 - 2.3e-18 66.9 0.1 2.6e-18 66.7 0.1 1.0 1 0 0 1 1 1 1 GrpB protein DDE_3 PF13358.6 ETZ04786.1 - 9.3e-07 28.7 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TIG_plexin PF17960.1 ETZ04786.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 TIG domain DDE_3 PF13358.6 ETZ04787.1 - 0.00033 20.4 0.0 0.00038 20.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M50 PF02163.22 ETZ04790.1 - 5e-56 189.7 0.0 6.6e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 ETZ04790.1 - 5.8e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ETZ04790.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Peptidase_M50B PF13398.6 ETZ04790.1 - 0.29 10.8 6.5 0.18 11.4 0.4 2.9 2 1 0 2 2 2 0 Peptidase M50B-like Glu-tRNAGln PF02686.15 ETZ04791.1 - 3.2e-07 30.6 0.0 5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Osmo_MPGsynth PF09488.10 ETZ04791.1 - 0.018 13.7 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Amidase PF01425.21 ETZ04792.1 - 2.1e-142 475.3 0.0 2.4e-142 475.1 0.0 1.0 1 0 0 1 1 1 1 Amidase HTH_psq PF05225.16 ETZ04794.1 - 0.0073 16.0 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 ETZ04794.1 - 0.0079 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain ETC_C1_NDUFA5 PF04716.14 ETZ04796.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 ETC complex I subunit conserved region BPL_LplA_LipB PF03099.19 ETZ04797.1 - 2.4e-10 40.4 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SBP_bac_5 PF00496.22 ETZ04798.1 - 1.1e-43 149.6 0.4 1.7e-43 149.1 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF1033 PF06279.11 ETZ04798.1 - 0.98 9.6 6.4 6.3 7.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) RRF PF01765.19 ETZ04799.1 - 5.8e-37 127.2 0.2 6.7e-37 126.9 0.2 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Nucleocapsid-N PF11030.8 ETZ04799.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N Gp_dh_C PF02800.20 ETZ04799.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 ETZ04802.1 - 3e-50 171.0 0.2 3.4e-50 170.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ04802.1 - 8.3e-48 162.4 0.3 1e-47 162.2 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ04802.1 - 1.3e-12 48.0 0.1 2e-12 47.4 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETZ04802.1 - 1.4e-06 28.0 0.4 3.1e-06 26.8 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETZ04802.1 - 0.002 18.1 0.1 0.003 17.5 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 ETZ04802.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ETZ04802.1 - 0.012 16.0 0.1 0.038 14.4 0.1 1.8 2 1 0 2 2 2 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 ETZ04802.1 - 0.016 14.6 1.2 0.12 11.7 1.2 2.1 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETZ04802.1 - 0.039 13.0 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF5012 PF16404.5 ETZ04802.1 - 0.046 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) NmrA PF05368.13 ETZ04802.1 - 0.056 13.0 0.1 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DUF2151 PF10221.9 ETZ04802.1 - 0.089 11.4 0.3 0.14 10.8 0.2 1.3 1 1 0 1 1 1 0 Cell cycle and development regulator THF_DHG_CYH_C PF02882.19 ETZ04802.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ABC_tran PF00005.27 ETZ04803.1 - 6.9e-34 117.3 0.0 1.2e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ04803.1 - 1.4e-20 74.1 19.8 2.1e-20 73.5 19.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ04803.1 - 9.3e-08 31.8 0.1 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 ETZ04803.1 - 0.0074 16.3 0.0 0.29 11.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TrkA_N PF02254.18 ETZ04803.1 - 0.012 15.8 0.0 0.21 11.9 0.0 2.5 1 1 0 2 2 2 0 TrkA-N domain AAA_29 PF13555.6 ETZ04803.1 - 0.02 14.6 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ETZ04803.1 - 0.024 15.0 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ETZ04803.1 - 0.029 14.5 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PIRT PF15099.6 ETZ04803.1 - 0.043 13.4 0.2 0.043 13.4 0.2 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family RsgA_GTPase PF03193.16 ETZ04803.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Acetyltransf_7 PF13508.7 ETZ04804.1 - 1.5e-11 44.5 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04804.1 - 3.5e-11 43.4 0.0 4.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ04804.1 - 5.5e-11 42.5 0.0 6e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETZ04804.1 - 2.2e-06 27.6 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ETZ04804.1 - 5.8e-05 23.2 0.0 7.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ETZ04804.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 ETZ04804.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase TIP41 PF04176.13 ETZ04805.1 - 0.051 13.1 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 TIP41-like family L51_S25_CI-B8 PF05047.16 ETZ04805.1 - 0.089 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain POTRA_1 PF08478.10 ETZ04806.1 - 1.7e-14 53.9 0.0 3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 POTRA domain, FtsQ-type FtsQ PF03799.15 ETZ04806.1 - 4.2e-08 34.0 0.0 7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ FtsA PF14450.6 ETZ04807.1 - 1e-23 83.7 0.0 3.2e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 ETZ04807.1 - 7.1e-11 42.4 0.0 1.6e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 ETZ04807.1 - 5.6e-09 35.3 0.0 1.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 ETZ04807.1 - 7.7e-07 28.4 0.0 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FGGY_C PF02782.16 ETZ04807.1 - 2.3e-06 27.5 0.0 9.3e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Actin PF00022.19 ETZ04807.1 - 0.048 12.3 0.1 2.3 6.8 0.0 2.3 1 1 1 2 2 2 0 Actin Tubulin PF00091.25 ETZ04808.1 - 5.3e-38 131.2 0.0 9.8e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 ETZ04808.1 - 3.4e-24 85.0 0.3 7.3e-24 83.9 0.3 1.6 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 ETZ04808.1 - 0.026 13.7 6.8 0.17 11.0 0.0 2.6 1 1 1 2 2 2 0 Tubulin like ACCA PF03255.14 ETZ04809.1 - 4.2e-51 172.6 0.0 6.3e-51 172.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 ETZ04809.1 - 9.7e-17 60.8 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ETZ04809.1 - 0.044 13.3 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DDE_Tnp_IS1 PF03400.13 ETZ04810.1 - 0.021 15.2 1.7 0.038 14.3 0.3 2.0 2 0 0 2 2 2 0 IS1 transposase MHC_I_C PF06623.11 ETZ04810.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 MHC_I C-terminus Sugar_tr PF00083.24 ETZ04811.1 - 4.7e-27 95.0 37.7 6.7e-19 68.1 13.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETZ04811.1 - 1.4e-18 67.0 52.8 2.7e-09 36.4 21.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_kinase PF00696.28 ETZ04812.1 - 1.9e-47 161.9 0.1 2.9e-47 161.3 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Xpo1 PF08389.12 ETZ04812.1 - 0.098 12.7 1.7 0.18 11.9 1.7 1.4 1 0 0 1 1 1 0 Exportin 1-like protein NMO PF03060.15 ETZ04813.1 - 1.8e-46 159.1 0.1 3.5e-31 108.8 0.0 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ETZ04813.1 - 2.4e-06 26.8 0.6 4.1e-06 26.1 0.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETZ04813.1 - 9.5e-05 21.5 0.0 0.03 13.3 0.0 2.4 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 ETZ04813.1 - 0.00018 20.8 0.2 0.00032 20.0 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 ETZ04813.1 - 0.034 13.4 0.1 0.056 12.7 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PI3K_P85_iSH2 PF16454.5 ETZ04814.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SesA PF17107.5 ETZ04814.1 - 0.042 14.1 0.1 0.057 13.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases XhlA PF10779.9 ETZ04814.1 - 0.14 12.4 0.5 0.2 11.8 0.5 1.2 1 0 0 1 1 1 0 Haemolysin XhlA TFIIS_M PF07500.14 ETZ04815.1 - 0.1 13.1 0.1 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain HSP70 PF00012.20 ETZ04817.1 - 2.2e-264 878.2 9.7 2.5e-264 878.0 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETZ04817.1 - 1.3e-14 53.8 11.6 1.3e-13 50.5 0.5 2.9 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 ETZ04817.1 - 0.0015 18.9 2.9 1.4 9.4 0.0 3.3 3 0 0 3 3 3 2 Cell division protein FtsA DUF3287 PF11690.8 ETZ04817.1 - 0.075 12.8 4.0 0.29 10.9 3.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) TRPM_tetra PF16519.5 ETZ04817.1 - 0.22 11.6 2.9 0.74 10.0 2.9 1.8 1 0 0 1 1 1 0 Tetramerisation domain of TRPM DDE_Tnp_1 PF01609.21 ETZ04820.1 - 0.0023 17.6 0.1 0.0038 16.9 0.1 1.5 1 1 0 1 1 1 1 Transposase DDE domain SAWADEE PF16719.5 ETZ04820.1 - 2.3 8.2 5.5 8.5 6.4 3.5 2.0 1 1 1 2 2 2 0 SAWADEE domain Aminotran_4 PF01063.19 ETZ04822.1 - 9.2e-45 153.2 0.0 1.1e-44 153.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV SNARE_assoc PF09335.11 ETZ04823.1 - 3.4e-10 40.4 8.8 3.4e-10 40.4 8.8 2.5 1 1 2 3 3 3 1 SNARE associated Golgi protein CcmD PF04995.14 ETZ04823.1 - 0.26 11.4 0.3 0.26 11.4 0.3 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Selenoprotein_S PF06936.11 ETZ04823.1 - 0.28 11.0 1.9 0.49 10.2 0.4 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) CrgA PF06781.12 ETZ04823.1 - 5.9 7.0 8.1 18 5.4 6.5 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF659 PF04937.15 ETZ04824.1 - 0.019 14.8 0.1 0.062 13.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) UDG PF03167.19 ETZ04826.1 - 8.3e-36 123.3 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_S7 PF00177.21 ETZ04827.1 - 5.1e-59 198.2 0.9 5.6e-59 198.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Phage_TAC_12 PF12363.8 ETZ04827.1 - 0.0055 17.1 0.0 0.019 15.3 0.0 1.7 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC Ribosom_S12_S23 PF00164.25 ETZ04828.1 - 3e-39 133.1 0.5 3.6e-39 132.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S9 PF00380.19 ETZ04829.1 - 6.8e-41 139.6 0.0 8.6e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 ETZ04830.1 - 3.9e-44 149.9 0.1 4.5e-44 149.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S16 PF00886.19 ETZ04831.1 - 1.8e-18 66.4 0.0 2.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 DUF179 PF02622.15 ETZ04832.1 - 6e-27 94.6 0.0 7.4e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 YajC PF02699.15 ETZ04833.1 - 5.2e-20 71.1 0.0 6.3e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 ETZ04833.1 - 0.011 16.0 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Dala_Dala_lig_C PF07478.13 ETZ04834.1 - 1.3e-50 171.8 0.0 1.6e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 ETZ04834.1 - 4e-19 69.0 0.0 1.1e-18 67.5 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 ETZ04834.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ETZ04834.1 - 0.00048 19.8 0.0 0.0043 16.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ETZ04834.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.9 2 1 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 ETZ04834.1 - 0.064 13.0 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF917 PF06032.12 ETZ04834.1 - 0.074 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) MitMem_reg PF13012.6 ETZ04835.1 - 0.13 12.7 1.3 0.19 12.2 0.2 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function YlqD PF11068.8 ETZ04835.1 - 0.6 10.5 9.4 0.054 13.9 3.3 2.1 2 0 0 2 2 2 0 YlqD protein HTH_23 PF13384.6 ETZ04836.1 - 0.00093 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ04836.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ETZ04836.1 - 0.072 13.0 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_Tnp_4 PF13613.6 ETZ04836.1 - 0.11 12.2 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease PRP3 PF08572.10 ETZ04837.1 - 0.012 15.4 1.2 0.012 15.4 1.2 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) UvrA_inter PF17760.1 ETZ04839.1 - 6.1e-31 106.7 0.2 2.2e-30 104.9 0.1 2.1 2 0 0 2 2 2 1 UvrA interaction domain ABC_tran PF00005.27 ETZ04839.1 - 1.2e-23 84.2 0.6 6.4e-11 42.9 0.1 4.3 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 ETZ04839.1 - 3.4e-10 39.7 0.1 0.53 9.7 0.0 4.1 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ04839.1 - 2.2e-07 31.4 0.0 0.015 15.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ETZ04839.1 - 2.3e-07 30.5 0.5 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ04839.1 - 4.6e-05 24.0 0.6 0.037 14.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETZ04839.1 - 9e-05 22.4 0.4 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 ETZ04839.1 - 9.9e-05 22.5 0.0 1.8 8.7 0.0 3.7 4 0 0 4 4 4 2 AAA domain DnaJ_CXXCXGXG PF00684.19 ETZ04839.1 - 0.00025 21.4 8.3 0.04 14.3 1.3 2.6 2 0 0 2 2 2 2 DnaJ central domain ATPase PF06745.13 ETZ04839.1 - 0.00036 19.9 0.0 0.45 9.8 0.0 2.5 2 0 0 2 2 2 2 KaiC AAA_18 PF13238.6 ETZ04839.1 - 0.00057 20.4 0.1 2.1 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ETZ04839.1 - 0.00059 19.5 0.2 0.08 12.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 ETZ04839.1 - 0.0015 18.4 8.9 1.4 8.7 0.1 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETZ04839.1 - 0.002 18.4 1.6 0.19 12.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 ETZ04839.1 - 0.0043 16.8 1.1 3.5 7.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA12 PF10443.9 ETZ04839.1 - 0.0043 15.8 0.1 0.3 9.7 0.0 2.2 2 0 0 2 2 2 1 RNA12 protein cobW PF02492.19 ETZ04839.1 - 0.0064 16.1 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 ETZ04839.1 - 0.0094 15.5 0.1 1.7 8.1 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region DUF2075 PF09848.9 ETZ04839.1 - 0.013 14.7 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 ETZ04839.1 - 0.014 15.1 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 ETZ04839.1 - 0.021 14.3 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 ETZ04839.1 - 0.027 14.5 0.1 3.9 7.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ETZ04839.1 - 0.029 14.3 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 ETZ04839.1 - 0.032 13.9 1.4 37 3.9 0.0 3.5 4 0 0 4 4 3 0 AAA ATPase domain RNA_helicase PF00910.22 ETZ04839.1 - 0.036 14.5 0.1 4.1 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 ETZ04839.1 - 0.055 13.4 0.1 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Viral_helicase1 PF01443.18 ETZ04839.1 - 0.058 13.1 0.1 0.46 10.2 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 ETZ04839.1 - 0.087 11.8 0.1 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 ETZ04839.1 - 0.094 12.4 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 ETZ04839.1 - 0.11 11.5 0.7 2 7.4 0.1 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein ATPase_2 PF01637.18 ETZ04839.1 - 0.11 12.3 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 ETZ04839.1 - 0.12 12.1 0.1 5.2 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 ETZ04839.1 - 0.13 12.0 0.6 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activat PF00158.26 ETZ04839.1 - 0.17 11.6 0.1 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 ETZ04839.1 - 0.2 11.6 0.1 0.68 9.8 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 ETZ04839.1 - 0.2 11.7 0.7 27 4.9 0.1 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase BCA_ABC_TP_C PF12399.8 ETZ04839.1 - 0.42 10.6 1.3 37 4.4 0.3 2.6 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter TrkH PF02386.16 ETZ04841.1 - 7e-16 57.8 20.9 2.5e-14 52.6 7.9 2.8 1 1 1 2 2 2 2 Cation transport protein PgaD PF13994.6 ETZ04841.1 - 0.0093 16.0 0.4 0.0093 16.0 0.4 2.8 4 0 0 4 4 4 1 PgaD-like protein PNTB PF02233.16 ETZ04842.1 - 5.3e-140 467.4 9.0 6.6e-140 467.1 9.0 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 ETZ04842.1 - 4.8e-07 29.6 0.4 4.3e-06 26.5 0.3 2.4 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF3501 PF12007.8 ETZ04843.1 - 1e-31 110.4 0.0 1.4e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3501) Response_reg PF00072.24 ETZ04844.1 - 1.5e-24 86.3 0.0 2.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ETZ04844.1 - 9.7e-18 64.0 0.0 2.4e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal RMMBL PF07521.12 ETZ04845.1 - 1.7e-12 47.1 0.3 2.1e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ETZ04845.1 - 1.5e-11 44.2 0.1 2.9e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETZ04845.1 - 1.2e-10 41.7 0.2 2.3e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ETZ04845.1 - 0.00051 19.5 0.1 0.0019 17.7 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RNase_J_C PF17770.1 ETZ04845.1 - 0.017 16.1 0.1 0.035 15.2 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain Lactamase_B_3 PF13483.6 ETZ04845.1 - 0.019 14.9 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DNA_pol3_delta2 PF13177.6 ETZ04846.1 - 2.4e-21 76.2 0.0 3.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ETZ04846.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETZ04846.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain HTH_33 PF13592.6 ETZ04847.1 - 9.5e-06 25.2 0.1 1.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Ribul_P_3_epim PF00834.19 ETZ04849.1 - 2.1e-44 151.3 0.0 2.4e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family LacAB_rpiB PF02502.18 ETZ04850.1 - 5.9e-33 113.8 0.0 6.8e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase GCM PF03615.15 ETZ04850.1 - 0.17 11.7 0.1 0.35 10.8 0.0 1.5 2 0 0 2 2 2 0 GCM motif protein Topoisom_bac PF01131.20 ETZ04851.1 - 3e-121 405.3 0.0 3e-121 405.3 0.0 2.0 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 ETZ04851.1 - 4.5e-24 84.6 0.2 1.6e-23 82.9 0.1 2.1 2 0 0 2 2 2 1 Toprim domain Toprim_C_rpt PF13368.6 ETZ04851.1 - 3.5e-20 71.7 0.0 5e-11 42.4 0.0 3.1 1 1 1 2 2 2 2 Topoisomerase C-terminal repeat zf-C4_Topoisom PF01396.19 ETZ04851.1 - 5.1e-09 35.8 5.6 5.1e-09 35.8 5.6 2.2 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 ETZ04851.1 - 0.004 17.6 0.2 0.012 16.1 0.2 1.9 1 1 0 1 1 1 1 Toprim domain Spore_II_R PF09551.10 ETZ04851.1 - 5.2 7.5 8.8 8.8 6.8 4.0 2.8 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) DNA_processg_A PF02481.15 ETZ04852.1 - 3.2e-67 225.8 0.0 4.2e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 ETZ04852.1 - 2.3e-08 34.0 0.1 4.9e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 DprA winged helix domain Ribosomal_S4 PF00163.19 ETZ04853.1 - 3.1e-16 60.1 0.8 5.6e-16 59.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 ETZ04853.1 - 9.9e-12 44.4 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain FHA PF00498.26 ETZ04853.1 - 0.11 12.9 0.0 0.47 10.8 0.0 2.1 1 1 0 1 1 1 0 FHA domain S4_2 PF13275.6 ETZ04853.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 S4 domain EamA PF00892.20 ETZ04854.1 - 5.6e-20 71.9 36.6 6.6e-13 49.0 15.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_M23 PF01551.22 ETZ04855.1 - 4.8e-09 36.3 0.0 9.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M23 LysM PF01476.20 ETZ04855.1 - 1.4e-07 31.5 0.0 3.5e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 LysM domain DUF1161 PF06649.12 ETZ04855.1 - 6.7 7.0 5.8 0.78 10.0 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1161) tRNA-synt_2b PF00587.25 ETZ04856.1 - 4.3e-29 101.8 0.0 7.9e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ETZ04856.1 - 6.3e-23 81.1 0.7 1.2e-22 80.2 0.7 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain BicD PF09730.9 ETZ04857.1 - 0.0048 15.4 0.5 0.0052 15.3 0.5 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D COG2 PF06148.11 ETZ04857.1 - 0.031 14.3 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 OmdA PF13376.6 ETZ04858.1 - 2.3e-06 27.5 6.0 0.23 11.5 0.1 3.4 3 0 0 3 3 3 3 Bacteriocin-protection, YdeI or OmpD-Associated DUF5347 PF17282.2 ETZ04858.1 - 0.0014 18.9 1.3 0.0014 18.9 1.3 3.0 3 1 0 3 3 3 1 Family of unknown function (DUF5347) Sigma54_activ_2 PF14532.6 ETZ04858.1 - 0.034 14.3 1.4 0.6 10.2 0.3 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Met_gamma_lyase PF06838.11 ETZ04858.1 - 0.44 9.0 2.0 12 4.3 0.2 2.6 3 1 0 3 3 3 0 Methionine gamma-lyase DUF5552 PF17706.1 ETZ04858.1 - 0.58 9.9 2.3 7.7 6.2 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5552) DUF1825 PF08855.10 ETZ04858.1 - 3.6 7.6 7.5 8.3 6.4 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) tRNA-synt_1e PF01406.19 ETZ04859.1 - 1.2e-112 376.2 0.0 3.4e-112 374.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ETZ04859.1 - 5.4e-13 48.5 0.0 1.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 ETZ04859.1 - 1.1e-07 31.1 0.0 0.0012 17.9 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 ETZ04859.1 - 9.7e-07 27.4 0.0 9.8e-06 24.1 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 ETZ04859.1 - 0.00019 21.8 0.2 0.003 18.0 0.0 2.6 1 1 1 2 2 2 1 DALR domain UVR PF02151.19 ETZ04859.1 - 1.4 8.8 5.6 2.6 7.9 5.6 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif Glyco_transf_25 PF01755.17 ETZ04860.1 - 8.2e-20 71.5 0.0 3.6e-18 66.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) CtsR_C PF17727.1 ETZ04862.1 - 0.047 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain MotA_ExbB PF01618.16 ETZ04864.1 - 0.00014 21.6 0.1 0.00043 20.0 0.1 1.8 1 1 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF3267 PF11667.8 ETZ04864.1 - 2.8 8.3 8.6 4.9 7.5 6.9 2.2 2 0 0 2 2 2 0 Putative zincin peptidase MutS_V PF00488.21 ETZ04865.1 - 6e-82 274.2 0.0 1.2e-81 273.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 ETZ04865.1 - 1e-42 144.9 0.0 1.7e-41 141.0 0.0 2.6 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 ETZ04865.1 - 3.1e-30 105.8 0.1 6e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 ETZ04865.1 - 4.7e-19 69.0 0.0 1.2e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ETZ04865.1 - 2.6e-16 59.7 0.1 6.3e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 ETZ04865.1 - 0.0068 16.9 0.6 1.3 9.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain Response_reg PF00072.24 ETZ04866.1 - 3.9e-18 65.7 0.0 6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ETZ04866.1 - 1.2e-14 54.2 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal LptC PF06835.13 ETZ04867.1 - 1.5e-06 27.9 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related Fer2 PF00111.27 ETZ04868.1 - 1.1e-09 38.1 0.5 1.5e-09 37.7 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DAP_epimerase PF01678.19 ETZ04869.1 - 4.7e-15 55.8 0.0 1.7e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Diaminopimelate epimerase DUF4096 PF13340.6 ETZ04870.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) MFS_1 PF07690.16 ETZ04873.1 - 3.6e-31 108.4 41.3 3.6e-31 108.4 41.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3741 PF12552.8 ETZ04875.1 - 0.042 13.8 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) RCSD PF05177.12 ETZ04875.1 - 0.95 10.4 9.0 0.78 10.7 7.3 1.7 1 1 0 1 1 1 0 RCSD region ABC_tran PF00005.27 ETZ04876.1 - 4.6e-32 111.4 0.0 8.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ04876.1 - 1.5e-10 41.2 13.0 3e-10 40.2 13.0 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ04876.1 - 8e-07 28.7 0.5 2e-05 24.1 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ04876.1 - 0.00087 19.7 0.1 0.0018 18.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ETZ04876.1 - 0.002 18.1 0.2 0.0069 16.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ETZ04876.1 - 0.017 15.4 2.3 0.67 10.2 1.5 3.0 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETZ04876.1 - 0.03 14.2 1.9 2.5 8.0 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 ETZ04876.1 - 0.043 13.5 0.4 0.17 11.6 0.3 2.1 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.6 ETZ04876.1 - 0.061 13.1 0.2 0.95 9.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 ETZ04876.1 - 0.072 13.0 0.5 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 ETZ04876.1 - 0.082 13.3 0.8 1.1 9.7 0.8 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 ETZ04876.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Pex24p PF06398.11 ETZ04876.1 - 2.6 6.9 5.6 4.3 6.2 5.6 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF805 PF05656.14 ETZ04876.1 - 7.1 7.1 10.3 2.2 8.7 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF805) DDE_3 PF13358.6 ETZ04877.1 - 9.6e-11 41.6 0.1 1.4e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M1 PF01433.20 ETZ04877.1 - 0.067 12.8 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M1 domain YfiO PF13525.6 ETZ04878.1 - 8.7e-47 159.5 2.6 9.9e-47 159.3 2.3 1.3 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 ETZ04878.1 - 2.6e-22 79.5 4.4 1.4e-20 73.9 2.7 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETZ04878.1 - 4e-06 27.1 2.6 0.35 11.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ04878.1 - 6.1e-06 26.8 0.0 0.0012 19.5 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 ETZ04878.1 - 0.00026 20.8 0.3 0.00067 19.4 0.2 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain Stanniocalcin PF03298.13 ETZ04878.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Stanniocalcin family ANAPC3 PF12895.7 ETZ04878.1 - 0.33 11.2 5.4 1.5 9.1 4.4 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETZ04878.1 - 0.5 10.6 3.6 80 3.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DivIC PF04977.15 ETZ04879.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Septum formation initiator Cpn10 PF00166.21 ETZ04880.1 - 6.8e-35 119.0 0.1 7.5e-35 118.9 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit GatD_N PF18195.1 ETZ04880.1 - 0.0096 15.2 0.1 3.5 7.0 0.0 3.0 1 1 2 3 3 3 2 GatD N-terminal domain Cpn60_TCP1 PF00118.24 ETZ04881.1 - 3.4e-92 309.6 11.0 4.9e-92 309.1 11.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ChlI PF13541.6 ETZ04881.1 - 0.081 12.8 0.7 12 5.8 0.1 3.1 2 1 1 3 3 3 0 Subunit ChlI of Mg-chelatase Alpha-2-MRAP_C PF06401.11 ETZ04881.1 - 0.19 11.7 0.0 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Thioredoxin_4 PF13462.6 ETZ04882.1 - 3.7e-06 27.2 0.4 5.7e-06 26.6 0.4 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 ETZ04882.1 - 0.00019 21.4 0.3 0.025 14.5 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 ETZ04882.1 - 0.0017 18.7 0.2 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 ETZ04882.1 - 0.042 13.8 0.2 11 6.0 0.1 2.3 2 0 0 2 2 2 0 AhpC/TSA family CSTF2_hinge PF14327.6 ETZ04882.1 - 0.062 13.8 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Peptidase_M26_N PF05342.14 ETZ04882.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Glutaredoxin PF00462.24 ETZ04882.1 - 0.13 12.5 0.1 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin ABC_membrane PF00664.23 ETZ04883.1 - 2.7e-35 122.4 12.4 3.7e-35 121.9 12.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ETZ04883.1 - 1.1e-29 103.7 0.0 2.5e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ04883.1 - 1e-06 28.3 0.0 0.00075 19.0 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETZ04883.1 - 0.0074 16.1 0.2 0.34 10.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETZ04883.1 - 0.008 16.7 1.0 0.06 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETZ04883.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sec10 PF07393.11 ETZ04883.1 - 0.019 13.4 0.2 0.031 12.7 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 ResIII PF04851.15 ETZ04883.1 - 0.024 14.6 0.2 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ETZ04883.1 - 0.036 14.4 0.1 0.26 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 ETZ04883.1 - 0.044 12.6 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 ETZ04883.1 - 0.049 13.9 0.4 0.65 10.3 0.1 2.7 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETZ04883.1 - 0.053 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 ETZ04883.1 - 0.081 13.0 1.7 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 ETZ04883.1 - 0.082 12.8 0.6 14 5.5 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ETZ04883.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ETZ04883.1 - 0.16 11.8 0.0 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase SSB PF00436.25 ETZ04884.1 - 9.6e-36 122.0 0.6 1.1e-35 121.8 0.6 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PROCN PF08083.11 ETZ04884.1 - 0.0066 15.2 0.2 0.0078 15.0 0.2 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain PI-TkoII_IV PF18714.1 ETZ04884.1 - 0.025 14.1 0.2 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV CspB_prodomain PF18425.1 ETZ04884.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Csp protease B prodomain PCRF PF03462.18 ETZ04885.1 - 1.9e-61 207.3 0.6 1.9e-61 207.3 0.6 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ETZ04885.1 - 3.6e-41 139.7 3.0 8.2e-41 138.6 3.0 1.6 1 0 0 1 1 1 1 RF-1 domain Coilin_N PF15862.5 ETZ04885.1 - 0.013 15.3 1.5 0.032 14.0 1.2 1.7 2 0 0 2 2 2 0 Coilin N-terminus MIR PF02815.19 ETZ04885.1 - 0.068 13.0 0.1 0.068 13.0 0.1 1.7 2 0 0 2 2 2 0 MIR domain Rotamase PF00639.21 ETZ04888.1 - 8.5e-08 33.1 0.0 2.3e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ETZ04888.1 - 5.1e-06 27.0 0.0 1.4e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Methyltransf_23 PF13489.6 ETZ04890.1 - 6.7e-16 58.6 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ04890.1 - 1.7e-11 44.6 0.0 3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ04890.1 - 5.1e-10 39.9 0.0 8.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04890.1 - 1.3e-09 38.1 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ04890.1 - 1.8e-08 35.0 0.0 2.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ETZ04890.1 - 5.7e-06 26.1 0.0 7.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 ETZ04890.1 - 0.00049 19.5 0.0 0.00067 19.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ETZ04890.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ETZ04890.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ETZ04890.1 - 0.006 15.5 0.0 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Glycos_transf_4 PF00953.21 ETZ04891.1 - 4.2e-30 104.8 15.4 4.2e-30 104.8 15.4 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 ETZ04891.1 - 4.5 7.0 11.0 0.2 11.3 4.9 2.1 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 AAA_32 PF13654.6 ETZ04893.1 - 0.015 14.1 3.0 0.017 13.9 3.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4446 PF14584.6 ETZ04893.1 - 0.07 13.1 2.2 0.11 12.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) AI-2E_transport PF01594.16 ETZ04893.1 - 0.13 11.3 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter MatP PF06303.12 ETZ04893.1 - 0.16 12.5 2.9 0.33 11.5 0.1 2.3 2 1 0 2 2 2 0 MatP N-terminal domain HTH_40 PF14493.6 ETZ04893.1 - 0.58 10.6 3.5 13 6.4 0.2 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 ETZ04896.1 - 0.0006 19.8 0.3 0.0021 18.1 0.3 1.7 1 1 0 1 1 1 1 Transposase OMP_b-brl PF13505.6 ETZ04897.1 - 3.7e-05 23.9 3.3 0.00022 21.4 3.3 2.1 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ04897.1 - 0.063 13.0 0.0 0.18 11.5 0.0 1.7 1 1 1 2 2 2 0 OmpA-like transmembrane domain PEP-utilizers_C PF02896.18 ETZ04898.1 - 1.2e-69 234.7 0.0 1.8e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 ETZ04898.1 - 5.9e-34 117.8 0.1 3.4e-21 75.9 0.0 3.4 2 1 1 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 ETZ04898.1 - 8.8e-17 60.6 0.7 1.7e-16 59.7 0.7 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Glyoxal_oxid_N PF07250.11 ETZ04898.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Competence PF03772.16 ETZ04899.1 - 1.2e-47 162.5 26.4 2.4e-47 161.5 26.4 1.5 1 0 0 1 1 1 1 Competence protein DUF4131 PF13567.6 ETZ04899.1 - 0.0055 16.4 0.0 0.0055 16.4 0.0 3.9 4 1 0 4 4 4 2 Domain of unknown function (DUF4131) CPP1-like PF11833.8 ETZ04899.1 - 0.057 13.1 0.1 0.057 13.1 0.1 2.1 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like KH_5 PF13184.6 ETZ04900.1 - 1.1e-21 76.7 0.6 2.2e-19 69.3 0.1 2.6 2 0 0 2 2 2 2 NusA-like KH domain NusA_N PF08529.11 ETZ04900.1 - 2.1e-15 57.1 0.0 6e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 NusA N-terminal domain KH_2 PF07650.17 ETZ04900.1 - 2.9e-07 30.2 2.1 3.8e-06 26.6 0.1 3.3 3 0 0 3 3 3 1 KH domain S1 PF00575.23 ETZ04900.1 - 2.6e-05 24.4 0.1 0.00012 22.4 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 ETZ04900.1 - 5.3e-05 23.0 0.2 0.0078 16.0 0.1 2.5 2 0 0 2 2 2 1 KH domain HHH_5 PF14520.6 ETZ04900.1 - 0.004 17.7 0.0 0.51 11.0 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF150 PF02576.17 ETZ04901.1 - 6.5e-11 42.5 0.7 9.7e-11 41.9 0.7 1.3 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 ETZ04901.1 - 0.0016 18.5 0.0 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 RimP C-terminal SH3 domain SDF PF00375.18 ETZ04902.1 - 2.3e-53 181.7 14.3 3e-53 181.2 14.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family zinc_ribbon_4 PF13717.6 ETZ04904.1 - 4.7e-11 42.4 0.2 7.6e-11 41.7 0.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 ETZ04904.1 - 1.9e-07 30.7 0.1 3.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-LSD1 PF06943.12 ETZ04904.1 - 3 7.8 6.0 0.68 9.8 0.8 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Pribosyltran_N PF13793.6 ETZ04905.1 - 3.5e-38 130.1 0.2 5.1e-35 119.9 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ETZ04905.1 - 9e-18 65.0 1.6 2.3e-17 63.6 1.0 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ETZ04905.1 - 1.1e-16 60.7 0.0 6.1e-16 58.3 0.0 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ETZ04905.1 - 8.8e-07 28.6 0.5 7.5e-06 25.5 0.3 2.0 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF4392 PF14336.6 ETZ04905.1 - 0.048 13.1 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) PRTase_2 PF15609.6 ETZ04905.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase tRNA-synt_His PF13393.6 ETZ04906.1 - 3.6e-34 118.4 0.0 4.3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ETZ04906.1 - 1.9e-10 40.8 0.3 1.9e-10 40.8 0.3 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ETZ04906.1 - 2.7e-06 27.5 0.0 9.3e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ETZ04906.1 - 0.0038 16.4 0.1 0.023 13.8 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) ABC_tran PF00005.27 ETZ04907.1 - 9.4e-31 107.2 0.6 1.4e-30 106.6 0.6 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ04907.1 - 1.2e-15 58.1 0.8 3e-08 33.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ04907.1 - 3.7e-12 46.2 4.0 9e-12 44.9 4.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETZ04907.1 - 5.6e-07 30.3 5.2 3e-06 27.9 5.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETZ04907.1 - 7.6e-07 28.8 1.2 9.9e-07 28.4 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA PF00004.29 ETZ04907.1 - 2e-06 28.2 1.1 0.029 14.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 ETZ04907.1 - 2.3e-05 23.4 0.1 0.08 11.7 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ETZ04907.1 - 2.4e-05 24.3 0.3 5.1e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_27 PF13514.6 ETZ04907.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETZ04907.1 - 0.00027 20.7 1.2 0.083 12.6 0.0 2.1 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 ETZ04907.1 - 0.00052 20.0 0.1 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ETZ04907.1 - 0.0012 18.7 5.5 0.013 15.2 0.5 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 ETZ04907.1 - 0.002 18.5 0.1 0.0036 17.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 ETZ04907.1 - 0.0032 17.5 0.1 0.0081 16.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ETZ04907.1 - 0.0054 17.0 0.6 0.019 15.2 0.6 1.8 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 ETZ04907.1 - 0.023 14.9 0.4 0.33 11.2 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ETZ04907.1 - 0.031 14.2 0.6 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 ETZ04907.1 - 0.047 13.6 0.2 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 ETZ04907.1 - 0.05 13.2 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ETZ04907.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 ETZ04907.1 - 0.14 11.9 0.2 0.43 10.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 ETZ04908.1 - 3e-26 92.2 29.5 4.3e-26 91.7 29.5 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Gly-zipper_Omp PF13488.6 ETZ04908.1 - 2.4 8.2 10.3 1.2 9.2 0.1 2.9 2 1 1 3 3 3 0 Glycine zipper ABC_sub_bind PF04392.12 ETZ04909.1 - 1.4e-81 273.9 8.0 1.6e-81 273.7 8.0 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_4 PF13407.6 ETZ04909.1 - 7.3e-11 42.1 3.0 6.2e-09 35.8 0.6 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain ANF_receptor PF01094.28 ETZ04909.1 - 6.6e-05 22.2 1.3 0.034 13.3 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Aldolase PF01081.19 ETZ04909.1 - 0.0018 17.8 0.5 0.0039 16.6 0.0 1.7 2 0 0 2 2 2 1 KDPG and KHG aldolase GARS_N PF02844.15 ETZ04909.1 - 0.032 15.0 0.8 0.84 10.5 0.1 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain DUF2099 PF09872.9 ETZ04909.1 - 0.042 13.0 0.3 0.11 11.6 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) Trp_repressor PF01371.19 ETZ04910.1 - 1.6e-21 76.2 0.0 1.8e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Trp repressor protein HTH_23 PF13384.6 ETZ04910.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ04910.1 - 0.0049 16.6 0.1 0.0077 16.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain CitMHS_2 PF16980.5 ETZ04913.1 - 1.7e-99 333.5 23.9 2.3e-99 333.1 23.9 1.0 1 0 0 1 1 1 1 Putative citrate transport CitMHS PF03600.16 ETZ04913.1 - 1.2e-12 47.7 10.1 2.1e-11 43.6 2.5 2.5 1 1 1 2 2 2 2 Citrate transporter DUF5134 PF17197.4 ETZ04913.1 - 0.01 15.8 0.7 0.03 14.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) YlaC PF10777.9 ETZ04913.1 - 0.74 9.6 5.2 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Inner membrane protein YlaC RNase_E_G PF10150.9 ETZ04914.1 - 7.7e-90 301.0 0.4 1.6e-89 299.9 0.4 1.6 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 ETZ04914.1 - 0.0015 18.8 0.1 0.053 13.9 0.0 3.0 2 0 0 2 2 2 1 S1 RNA binding domain RNase_PH PF01138.21 ETZ04915.1 - 2.6e-38 131.5 0.0 7.1e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 S1 PF00575.23 ETZ04915.1 - 7.6e-14 51.8 0.3 1.6e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 ETZ04915.1 - 3.6e-08 33.1 0.2 9.3e-08 31.8 0.2 1.8 1 0 0 1 1 1 1 KH domain RNase_PH_C PF03725.15 ETZ04915.1 - 0.00015 21.7 0.2 0.16 12.0 0.1 3.3 2 1 0 2 2 2 2 3' exoribonuclease family, domain 2 DUF3016 PF11454.8 ETZ04915.1 - 0.0014 18.4 0.1 0.071 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3016) PNPase PF03726.14 ETZ04915.1 - 0.0071 16.8 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_2 PF07650.17 ETZ04915.1 - 0.018 14.9 0.1 0.058 13.2 0.1 2.0 1 1 0 1 1 1 0 KH domain Ribosomal_S15 PF00312.22 ETZ04916.1 - 3.8e-28 97.5 0.4 4.6e-28 97.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 TruB_N PF01509.18 ETZ04917.1 - 4.8e-44 150.3 0.0 6.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ETZ04917.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain tRNA-synt_1c PF00749.21 ETZ04919.1 - 9.6e-60 202.1 0.0 1.4e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1b PF00579.25 ETZ04919.1 - 0.016 14.5 0.3 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DUF463 PF04317.12 ETZ04919.1 - 0.04 12.9 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 OSCP PF00213.18 ETZ04920.1 - 7.8e-08 32.6 0.0 9.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DDE_3 PF13358.6 ETZ04921.1 - 0.00074 19.3 0.9 0.12 12.2 0.2 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease KH_6 PF15985.5 ETZ04922.1 - 0.072 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 KH domain MraZ PF02381.18 ETZ04923.1 - 1.1e-18 67.0 0.0 2.9e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like Methyltransf_5 PF01795.19 ETZ04924.1 - 3.6e-82 276.3 0.0 1.4e-81 274.4 0.0 1.7 1 1 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 ETZ04924.1 - 0.049 14.3 0.0 0.19 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF3847 PF12958.7 ETZ04926.1 - 0.002 18.2 0.4 0.0026 17.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) DivIC PF04977.15 ETZ04926.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Asp_Glu_race PF01177.22 ETZ04927.1 - 3.6e-17 63.0 0.1 4.8e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase GHMP_kinases_N PF00288.26 ETZ04929.1 - 3.2e-09 36.9 0.1 2e-08 34.3 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain Chlorophyllase2 PF12740.7 ETZ04930.1 - 7e-10 38.2 0.0 1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ETZ04930.1 - 3.5e-08 33.0 0.1 5.4e-07 29.1 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 ETZ04930.1 - 8.3e-08 31.1 0.0 0.0045 15.6 0.1 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 ETZ04930.1 - 2.2e-07 30.8 0.0 6.4e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 ETZ04930.1 - 3.6e-07 29.5 0.0 5.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.7 ETZ04930.1 - 0.00016 21.5 0.1 0.36 10.6 0.1 2.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family PGAP1 PF07819.13 ETZ04930.1 - 0.0018 18.0 0.0 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Lipase PF00151.19 ETZ04930.1 - 0.0042 16.5 0.0 0.0086 15.4 0.0 1.4 1 1 0 1 1 1 1 Lipase Abhydrolase_2 PF02230.16 ETZ04930.1 - 0.01 15.6 0.0 0.088 12.6 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 ETZ04930.1 - 0.041 13.4 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Esterase PF00756.20 ETZ04930.1 - 0.058 13.0 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 ETZ04930.1 - 0.061 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 ETZ04930.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF915 PF06028.11 ETZ04930.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 ETZ04930.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 ETZ04930.1 - 0.15 12.0 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 ETZ04930.1 - 0.2 12.2 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cyclase PF04199.13 ETZ04931.1 - 7.8e-32 110.4 0.0 9.8e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Inos-1-P_synth PF01658.17 ETZ04931.1 - 0.077 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Glyoxalase PF00903.25 ETZ04932.1 - 9.2e-12 45.3 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ETZ04932.1 - 4.9e-06 26.5 0.0 7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain PAD_M PF08527.10 ETZ04932.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Glyoxalase_6 PF18029.1 ETZ04932.1 - 0.041 14.7 0.0 0.27 12.0 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Acetyltransf_1 PF00583.25 ETZ04933.1 - 8.1e-16 58.3 0.4 3.4e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04933.1 - 5.3e-14 52.4 0.5 7.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ04933.1 - 2.8e-10 40.2 0.0 0.0014 18.6 0.0 2.8 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ETZ04933.1 - 0.00053 19.5 0.2 0.096 12.1 0.1 2.1 2 0 0 2 2 2 2 Putative acetyl-transferase Acetyltransf_CG PF14542.6 ETZ04933.1 - 0.016 15.3 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GrpB PF04229.14 ETZ04934.1 - 1.9e-38 132.2 0.0 3.2e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 GrpB protein Acetyltransf_1 PF00583.25 ETZ04934.1 - 2e-08 34.5 0.2 1.1e-07 32.1 0.0 2.2 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ04934.1 - 0.0005 20.4 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ04934.1 - 0.0022 17.9 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Flp_C PF05202.12 ETZ04934.1 - 0.16 11.4 0.1 0.49 9.9 0.0 1.7 2 1 1 3 3 3 0 Recombinase Flp protein NUDIX PF00293.28 ETZ04935.1 - 1.7e-15 57.3 0.0 2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ETZ04935.1 - 0.00022 21.2 0.0 0.00029 20.8 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain adh_short PF00106.25 ETZ04938.1 - 2.1e-29 102.4 0.0 2.7e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETZ04938.1 - 3.7e-20 72.5 0.0 4.5e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETZ04938.1 - 8.7e-07 28.6 0.0 2.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETZ04938.1 - 5.7e-06 26.4 0.0 8.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETZ04938.1 - 0.00037 19.6 0.1 0.0026 16.8 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETZ04938.1 - 0.00043 20.2 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETZ04938.1 - 0.0094 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ETZ04938.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LDcluster4 PF18306.1 ETZ04938.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family adh_short PF00106.25 ETZ04939.1 - 5.6e-51 172.8 1.5 6.8e-51 172.5 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETZ04939.1 - 7e-51 173.0 0.6 8e-51 172.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETZ04939.1 - 6.7e-13 48.9 0.3 1e-12 48.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETZ04939.1 - 4.9e-07 29.5 0.1 7.3e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETZ04939.1 - 0.00027 20.9 0.1 0.00035 20.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 ETZ04939.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 ETZ04939.1 - 0.066 13.3 1.3 0.17 12.0 0.6 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MarR PF01047.22 ETZ04940.1 - 2.6e-12 46.5 0.3 5.4e-12 45.4 0.3 1.6 1 1 0 1 1 1 1 MarR family HTH_27 PF13463.6 ETZ04940.1 - 8.3e-10 39.0 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ETZ04940.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ETZ04940.1 - 0.00025 20.9 0.1 0.00095 19.1 0.0 1.9 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ETZ04940.1 - 0.0017 17.8 0.0 0.0045 16.5 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding PadR PF03551.14 ETZ04940.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 ETZ04940.1 - 0.039 14.3 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TFIIE_alpha PF02002.17 ETZ04940.1 - 0.06 13.2 0.2 0.1 12.5 0.2 1.5 1 1 0 1 1 1 0 TFIIE alpha subunit Fe_dep_repress PF01325.19 ETZ04940.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MerR PF00376.23 ETZ04940.1 - 0.092 12.5 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Phage_rep_O PF04492.13 ETZ04940.1 - 0.1 13.2 0.1 0.24 12.0 0.1 1.6 1 1 1 2 2 2 0 Bacteriophage replication protein O PRiA4_ORF3 PF07929.11 ETZ04941.1 - 1.1e-15 57.8 0.1 1.3e-15 57.5 0.1 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF3242 PF11586.8 ETZ04941.1 - 0.022 14.5 3.0 0.2 11.4 3.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3242) YCII PF03795.14 ETZ04942.1 - 4.3e-12 46.3 0.0 6.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain DUF4440 PF14534.6 ETZ04942.1 - 1.3e-06 28.8 0.1 1.9e-05 25.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ETZ04942.1 - 0.14 12.4 0.1 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain NUDIX PF00293.28 ETZ04943.1 - 8.1e-14 51.8 0.0 1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PhoQ_Sensor PF08918.10 ETZ04943.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor DUF2482 PF10655.9 ETZ04943.1 - 0.16 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) NUDIX PF00293.28 ETZ04944.1 - 3.8e-15 56.1 0.1 4.5e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain PhoQ_Sensor PF08918.10 ETZ04944.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 PhoQ Sensor AAA_18 PF13238.6 ETZ04945.1 - 1.2e-05 25.8 0.1 2.7e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ETZ04945.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA PF00004.29 ETZ04945.1 - 0.017 15.5 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ETZ04945.1 - 0.019 15.2 0.0 0.029 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETZ04945.1 - 0.082 13.2 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 ETZ04945.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 ETZ04945.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETZ04945.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 NTPase Ploopntkinase3 PF18751.1 ETZ04945.1 - 0.19 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 TehB PF03848.14 ETZ04946.1 - 0.024 14.0 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 ETZ04946.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4440 PF14534.6 ETZ04946.1 - 0.065 13.6 0.2 0.1 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MTS PF05175.14 ETZ04946.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 ETZ04946.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NUDIX PF00293.28 ETZ04947.1 - 8.1e-14 51.8 0.0 1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PhoQ_Sensor PF08918.10 ETZ04947.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor DUF2482 PF10655.9 ETZ04947.1 - 0.16 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) Acetyltransf_1 PF00583.25 ETZ04948.1 - 4.6e-14 52.7 0.0 5.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ04948.1 - 5.1e-12 45.8 0.1 7.2e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ04948.1 - 1.5e-10 41.4 0.0 2.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ04948.1 - 6.9e-06 26.2 0.0 8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETZ04948.1 - 3.8e-05 23.9 0.1 5.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ04948.1 - 0.00033 20.7 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase IF3_N PF05198.16 ETZ04948.1 - 0.031 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain FR47 PF08445.10 ETZ04948.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 ETZ04949.1 - 7.8e-14 52.2 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_8 PF13523.6 ETZ04949.1 - 2.4e-12 46.7 0.0 4.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETZ04949.1 - 8e-09 36.3 0.0 1.6e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Choline_kinase PF01633.20 ETZ04949.1 - 1.2e-08 34.8 0.8 2.6e-08 33.7 0.8 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Acetyltransf_1 PF00583.25 ETZ04949.1 - 1.1e-05 25.7 0.0 3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family RIO1 PF01163.22 ETZ04949.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 ETZ04949.1 - 0.037 12.9 0.1 0.056 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 ETZ04949.1 - 0.065 12.6 0.2 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein kinase domain Acetyltransf_10 PF13673.7 ETZ04949.1 - 0.14 12.1 0.0 1.2 9.1 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04950.1 - 6.6e-13 48.9 0.0 8.5e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ04950.1 - 1.7e-10 41.0 0.0 2.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ04950.1 - 1.2e-08 35.3 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ04950.1 - 0.077 13.1 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ04950.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 ETZ04951.1 - 3.7e-12 46.5 0.0 4.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ04951.1 - 2.2e-10 40.6 0.0 2.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ04951.1 - 2.1e-09 37.7 0.0 2.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ04951.1 - 0.00086 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pho86 PF11124.8 ETZ04951.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Methyltransf_25 PF13649.6 ETZ04952.1 - 0.0012 19.6 0.0 0.0025 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04952.1 - 0.0017 18.1 0.1 0.0019 18.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain APH PF01636.23 ETZ04953.1 - 1.2e-32 113.8 0.0 1.6e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ETZ04953.1 - 0.0033 16.4 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ETZ04953.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Methyltransf_25 PF13649.6 ETZ04954.1 - 4.4e-12 46.5 0.0 7.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ04954.1 - 8.6e-09 35.4 0.0 2e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ04954.1 - 1.3e-08 35.5 0.0 2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ04954.1 - 3.6e-08 33.3 0.0 5.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ04954.1 - 2.7e-06 27.9 0.0 4.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 ETZ04954.1 - 0.00029 20.1 0.0 0.0026 17.0 0.0 2.0 2 0 0 2 2 2 1 N2227-like protein TehB PF03848.14 ETZ04954.1 - 0.00044 19.7 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 ETZ04954.1 - 0.005 16.2 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 ETZ04954.1 - 0.022 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Acetyltransf_10 PF13673.7 ETZ04955.1 - 4.1e-13 49.4 0.0 5.3e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ04955.1 - 6.6e-10 39.3 0.1 8.5e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ04955.1 - 9.3e-10 38.8 0.0 1.1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ETZ04955.1 - 0.0084 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ETZ04955.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein H_PPase PF03030.16 ETZ04955.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Acetyltransf_13 PF13880.6 ETZ04955.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PanZ PF12568.8 ETZ04955.1 - 0.17 11.6 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Beta-lactamase PF00144.24 ETZ04956.1 - 0.0026 17.1 0.0 0.0029 16.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 ETZ04957.1 - 6.4e-30 104.5 0.0 8.2e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Delta_lysin PF05372.11 ETZ04957.1 - 0.16 11.2 1.9 0.25 10.7 0.3 2.0 2 0 0 2 2 2 0 Delta lysin family Glycoprotein PF03409.15 ETZ04958.1 - 0.037 12.9 0.2 0.04 12.8 0.2 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein AMNp_N PF10423.9 ETZ04959.1 - 1.1e-21 77.1 0.0 2.3e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 ETZ04959.1 - 1.9e-13 50.2 0.0 2.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily DNA_gyraseB PF00204.25 ETZ04960.1 - 4.9e-50 169.4 0.0 8.4e-50 168.6 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 ETZ04960.1 - 1.7e-26 92.2 0.0 3.8e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 ETZ04960.1 - 2.6e-21 76.2 0.0 4.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ETZ04960.1 - 4.6e-16 58.9 0.0 1.1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 ETZ04960.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MlaD PF02470.20 ETZ04961.1 - 5.8e-17 61.8 0.0 8.7e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 MlaD protein COX6C PF02937.15 ETZ04961.1 - 0.028 14.6 0.1 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc AAA_25 PF13481.6 ETZ04963.1 - 4.3e-17 62.3 0.1 8.6e-17 61.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 ETZ04963.1 - 1.2e-15 57.5 0.1 3.8e-14 52.6 0.1 2.1 1 1 0 1 1 1 1 KaiC ChlI PF13541.6 ETZ04963.1 - 4.1e-08 33.1 0.1 6.6e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Rubredoxin_2 PF18073.1 ETZ04963.1 - 4.4e-07 29.5 5.0 7.7e-07 28.7 5.0 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain DnaB_C PF03796.15 ETZ04963.1 - 1.6e-06 27.7 0.1 8.8e-06 25.2 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 ETZ04963.1 - 2.5e-05 24.6 0.1 6.2e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 ETZ04963.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_16 PF13191.6 ETZ04963.1 - 0.00018 21.9 0.1 0.00031 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ETZ04963.1 - 0.00062 20.2 0.0 0.0014 19.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.11 ETZ04963.1 - 0.0015 17.8 0.1 0.034 13.4 0.1 2.2 1 1 0 1 1 1 1 Rad51 NACHT PF05729.12 ETZ04963.1 - 0.0036 17.2 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TIP49 PF06068.13 ETZ04963.1 - 0.0049 16.1 0.1 0.0088 15.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain MCM PF00493.23 ETZ04963.1 - 0.005 16.0 0.0 0.014 14.5 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain AAA_19 PF13245.6 ETZ04963.1 - 0.0051 17.2 0.2 0.0094 16.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ETZ04963.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 1 1 NTPase AAA_24 PF13479.6 ETZ04963.1 - 0.0087 15.8 0.0 0.058 13.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETZ04963.1 - 0.01 15.6 0.1 0.037 13.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 ETZ04963.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETZ04963.1 - 0.044 13.5 0.2 0.078 12.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ETZ04963.1 - 0.049 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ETZ04963.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase GvpD PF07088.11 ETZ04963.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.4 1 1 0 1 1 1 0 GvpD gas vesicle protein TPP_enzyme_N PF02776.18 ETZ04963.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CbiA PF01656.23 ETZ04963.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 ETZ04963.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 ETZ04963.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin GrpE PF01025.19 ETZ04964.1 - 9.8e-39 132.7 2.2 1.1e-38 132.5 2.2 1.0 1 0 0 1 1 1 1 GrpE DUF2397 PF09660.10 ETZ04964.1 - 0.0023 16.9 0.1 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) Sds3 PF08598.11 ETZ04964.1 - 0.0098 15.9 0.6 0.01 15.8 0.6 1.2 1 0 0 1 1 1 1 Sds3-like Titin_Ig-rpts PF06582.12 ETZ04964.1 - 0.13 12.2 0.4 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Titin repeat DUF4337 PF14235.6 ETZ04964.1 - 0.37 10.9 3.1 0.52 10.4 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HrcA PF01628.21 ETZ04965.1 - 2.2e-26 93.1 0.0 3.2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 HrcA protein C terminal domain Fe_dep_repress PF01325.19 ETZ04965.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HrcA_DNA-bdg PF03444.15 ETZ04965.1 - 0.0024 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Rrf2 PF02082.20 ETZ04965.1 - 0.012 15.9 0.0 0.035 14.5 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator Ndc80_HEC PF03801.13 ETZ04965.1 - 0.052 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family FMN_bind PF04205.14 ETZ04965.1 - 0.053 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 FMN-binding domain HTH_27 PF13463.6 ETZ04965.1 - 0.082 13.4 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 ETZ04965.1 - 0.11 12.4 0.1 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 ETZ04965.1 - 0.13 12.3 0.1 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_S11 PF00768.20 ETZ04966.1 - 3.3e-44 151.1 0.0 4.3e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 ETZ04966.1 - 6.1e-10 39.0 0.0 7.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 ETZ04966.1 - 0.033 13.4 0.0 3.4 6.8 0.0 2.7 2 1 1 3 3 3 0 Beta-lactamase SMC_N PF02463.19 ETZ04967.1 - 1.2e-16 60.8 0.0 1.1e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETZ04967.1 - 5.4e-10 40.1 0.0 8.7e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ETZ04967.1 - 1.1e-09 38.5 0.0 1.1e-07 31.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ETZ04967.1 - 1.4e-06 28.3 0.1 3.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ETZ04967.1 - 4.8e-05 23.5 0.0 8.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ETZ04967.1 - 0.00017 21.5 0.1 0.31 10.9 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 ETZ04967.1 - 0.00062 19.5 0.0 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ETZ04967.1 - 0.0014 19.2 0.1 0.013 16.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter DUF2813 PF11398.8 ETZ04967.1 - 0.016 14.5 2.4 0.12 11.6 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_22 PF13401.6 ETZ04967.1 - 0.041 14.2 0.0 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 ETZ04967.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETZ04967.1 - 0.14 11.9 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain OmpA PF00691.20 ETZ04968.1 - 3.3e-14 53.0 0.0 1.4e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 OmpA family O-antigen_lig PF13425.6 ETZ04968.1 - 0.25 10.1 1.6 0.34 9.7 1.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF5070 PF16802.5 ETZ04968.1 - 0.46 10.5 6.4 0.55 10.2 1.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5070) Exonuc_VII_L PF02601.15 ETZ04968.1 - 1.3 8.6 6.9 1.9 8.0 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 ETZ04968.1 - 2.1 8.1 9.6 0.12 12.2 3.9 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF5401 PF17380.2 ETZ04968.1 - 4.6 5.2 13.6 5.9 4.8 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Imm21 PF15589.6 ETZ04969.1 - 0.062 13.3 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 Immunity protein 21 DUF503 PF04456.12 ETZ04970.1 - 0.054 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Transgly PF00912.22 ETZ04972.1 - 1.8e-57 193.7 0.0 2.9e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ETZ04972.1 - 8.5e-30 104.0 0.0 1.9e-29 102.8 0.0 1.5 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain CDC45 PF02724.14 ETZ04972.1 - 9.1e-05 20.9 10.7 0.00014 20.4 10.7 1.2 1 0 0 1 1 1 1 CDC45-like protein CNDH2_C PF16858.5 ETZ04972.1 - 0.00037 20.5 4.5 0.00061 19.8 4.5 1.3 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SGT1 PF07093.11 ETZ04972.1 - 0.0083 14.6 4.9 0.014 13.9 4.9 1.4 1 0 0 1 1 1 1 SGT1 protein TrmB PF01978.19 ETZ04972.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RXT2_N PF08595.11 ETZ04972.1 - 0.019 15.0 13.7 0.061 13.3 13.7 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 ETZ04972.1 - 0.036 12.3 26.3 0.054 11.7 26.3 1.1 1 0 0 1 1 1 0 Nop14-like family CtsR_C PF17727.1 ETZ04972.1 - 0.041 14.0 0.1 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain SAPS PF04499.15 ETZ04972.1 - 0.047 12.5 4.6 0.065 12.0 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 ETZ04972.1 - 0.61 9.4 29.4 0.99 8.8 29.4 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 ETZ04972.1 - 0.71 8.4 28.5 1.1 7.8 28.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 ETZ04972.1 - 0.77 9.3 23.7 1.6 8.3 23.7 1.5 1 0 0 1 1 1 0 PPP4R2 Apt1 PF10351.9 ETZ04972.1 - 0.93 8.3 8.9 2 7.2 8.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_3_Rpc31 PF11705.8 ETZ04972.1 - 1.3 9.2 31.6 2.7 8.2 31.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 ETZ04972.1 - 1.5 8.0 25.6 2.8 7.2 25.6 1.3 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 ETZ04972.1 - 2.5 7.7 22.3 4.7 6.8 22.3 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 ETZ04972.1 - 3.2 5.8 35.8 1.1 7.2 33.1 1.5 2 0 0 2 2 2 0 DNA polymerase phi FAM60A PF15396.6 ETZ04972.1 - 3.9 7.4 7.5 8.4 6.3 7.5 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.10 ETZ04972.1 - 4.8 7.5 20.7 13 6.0 20.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 ETZ04972.1 - 4.9 6.5 25.1 10 5.4 25.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) tRNA_synt_2f PF02092.17 ETZ04973.1 - 3e-126 422.5 0.0 3.9e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DDE_Tnp_1 PF01609.21 ETZ04974.1 - 0.029 14.0 0.9 0.29 10.7 0.9 2.0 1 1 0 1 1 1 0 Transposase DDE domain DDE_Tnp_IS240 PF13610.6 ETZ04974.1 - 0.096 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 DDE domain PseudoU_synth_2 PF00849.22 ETZ04976.1 - 4.6e-33 114.6 0.2 6.7e-33 114.0 0.2 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ETZ04976.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 S4 domain TGT PF01702.18 ETZ04977.1 - 7.7e-98 327.9 0.0 9.5e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase FAM86 PF14904.6 ETZ04977.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function Peptidase_M41 PF01434.18 ETZ04979.1 - 6.3e-62 208.8 0.1 9.9e-62 208.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ETZ04979.1 - 2.8e-45 154.0 0.0 8.9e-45 152.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETZ04979.1 - 5.6e-12 45.3 0.5 1.6e-11 43.8 0.2 2.0 2 0 0 2 2 1 1 AAA+ lid domain FtsH_ext PF06480.15 ETZ04979.1 - 3.5e-08 33.8 1.2 5.6e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular TIP49 PF06068.13 ETZ04979.1 - 1.5e-05 24.4 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 ETZ04979.1 - 1.6e-05 24.9 0.0 7.8e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ04979.1 - 0.00012 22.5 2.4 0.012 16.0 0.3 3.0 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ETZ04979.1 - 0.00012 21.8 0.0 0.00051 19.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETZ04979.1 - 0.00058 20.1 0.1 0.045 14.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 ETZ04979.1 - 0.0029 17.8 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETZ04979.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ETZ04979.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ETZ04979.1 - 0.016 15.4 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 ETZ04979.1 - 0.019 15.2 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETZ04979.1 - 0.024 15.0 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 ETZ04979.1 - 0.03 14.8 0.1 0.095 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETZ04979.1 - 0.036 13.6 0.3 0.18 11.3 0.3 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 ETZ04979.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain OppC_N PF12911.7 ETZ04979.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Zeta_toxin PF06414.12 ETZ04979.1 - 0.076 12.3 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 ETZ04979.1 - 0.087 12.4 0.7 0.43 10.1 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 ETZ04979.1 - 0.097 13.2 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4131 PF13567.6 ETZ04979.1 - 0.098 12.3 0.0 0.098 12.3 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4131) SurA_N_3 PF13624.6 ETZ04979.1 - 0.1 12.4 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain AAA_24 PF13479.6 ETZ04979.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ETZ04979.1 - 0.13 11.3 0.0 0.39 9.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 ETZ04979.1 - 0.14 11.6 0.6 0.46 9.9 0.6 1.8 1 0 0 1 1 1 0 PhoH-like protein DDE_Tnp_IS1 PF03400.13 ETZ04980.1 - 0.016 15.6 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 IS1 transposase Thioredoxin_7 PF13899.6 ETZ04982.1 - 6.8e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DsbC PF11412.8 ETZ04982.1 - 1.5e-05 25.0 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredox_DsbH PF03190.15 ETZ04982.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Exonuc_VII_S PF02609.16 ETZ04983.1 - 1.2e-17 63.7 3.3 1.6e-17 63.3 3.3 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit DUF4096 PF13340.6 ETZ04985.1 - 1.6e-21 76.3 0.1 1.8e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) PFEMP PF03011.15 ETZ04985.1 - 0.042 14.5 0.1 0.042 14.5 0.1 1.1 1 0 0 1 1 1 0 PFEMP DBL domain MacB_PCD PF12704.7 ETZ04986.1 - 2.4e-14 54.1 0.0 3.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 ETZ04986.1 - 1.6e-12 47.7 1.6 1.6e-12 47.7 1.6 3.2 3 0 0 3 3 3 1 FtsX-like permease family NPCC PF08058.11 ETZ04986.1 - 0.071 13.2 0.8 0.17 11.9 0.8 1.7 1 0 0 1 1 1 0 Nuclear pore complex component SIT PF15330.6 ETZ04986.1 - 1.5 9.3 4.3 3.6 8.1 1.5 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TauE PF01925.19 ETZ04986.1 - 1.8 8.2 14.2 0.42 10.2 8.0 2.4 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE ABC_tran PF00005.27 ETZ04987.1 - 1.8e-31 109.5 0.0 2.5e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ04987.1 - 1.3e-07 31.8 0.6 0.0088 15.9 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETZ04987.1 - 5.5e-05 22.8 0.2 0.00012 21.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ETZ04987.1 - 0.00033 20.2 0.1 0.00069 19.1 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ04987.1 - 0.018 15.4 1.4 0.052 13.9 1.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 ETZ04987.1 - 0.033 14.4 0.0 0.45 10.8 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 ETZ04987.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 ETZ04987.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 ETZ04987.1 - 0.14 10.7 0.1 0.46 9.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ETZ04987.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETZ04987.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ETZ04987.1 - 0.24 11.1 0.4 4.2 7.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain GST_N_3 PF13417.6 ETZ04988.1 - 3e-12 46.8 0.0 5.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETZ04988.1 - 1.2e-06 28.7 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETZ04988.1 - 4.7e-06 26.7 0.1 8.3e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETZ04988.1 - 0.00029 21.0 0.1 0.002 18.3 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETZ04988.1 - 0.0011 19.2 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETZ04988.1 - 0.0077 16.2 0.2 0.021 14.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Peptidase_A8 PF01252.18 ETZ04989.1 - 3.5e-31 108.3 7.7 4.5e-31 108.0 7.7 1.1 1 0 0 1 1 1 1 Signal peptidase (SPase) II DUF3035 PF11233.8 ETZ04990.1 - 0.0012 19.2 0.2 0.0022 18.3 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3035) PSP PF04046.16 ETZ04990.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 PSP DnaJ_C PF01556.18 ETZ04992.1 - 1.2e-32 113.0 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETZ04992.1 - 3e-24 84.9 3.8 3e-24 84.9 3.8 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ETZ04992.1 - 2e-11 44.1 18.9 4e-11 43.1 18.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ETZ04992.1 - 1.2 9.1 19.2 0.92 9.5 5.6 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_L17 PF01196.19 ETZ04993.1 - 3e-27 95.4 0.0 3.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_A_CTD PF03118.15 ETZ04994.1 - 1.9e-21 75.6 0.0 3.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 ETZ04994.1 - 1e-20 72.9 0.0 1.5e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 ETZ04994.1 - 1.3e-15 57.8 0.0 9.3e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 ETZ04994.1 - 0.089 12.6 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S11 PF00411.19 ETZ04995.1 - 6e-39 132.9 0.2 7.1e-39 132.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DmpG_comm PF07836.11 ETZ04995.1 - 0.013 15.0 0.1 0.029 13.9 0.0 1.7 1 1 1 2 2 2 0 DmpG-like communication domain PEP-utilizers_C PF02896.18 ETZ04995.1 - 0.14 11.2 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Ribosomal_S13 PF00416.22 ETZ04996.1 - 6.3e-27 94.5 2.6 1.8e-25 89.8 2.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ETZ04996.1 - 0.022 13.5 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) OmpA PF00691.20 ETZ04997.1 - 2.1e-13 50.5 0.0 2.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 OmpA family FliJ PF02050.16 ETZ04998.1 - 0.011 16.0 0.4 0.011 16.0 0.4 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein FAM76 PF16046.5 ETZ04998.1 - 2.6 7.3 8.4 4.3 6.6 8.4 1.5 1 0 0 1 1 1 0 FAM76 protein MDD_C PF18376.1 ETZ04999.1 - 1.5e-21 77.0 0.1 1.7e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain Acetyltransf_7 PF13508.7 ETZ05001.1 - 5.2e-06 26.8 0.0 8.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ05001.1 - 1.8e-05 24.6 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ05001.1 - 0.00015 22.0 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETZ05001.1 - 0.033 14.3 0.1 0.31 11.1 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain His_Phos_1 PF00300.22 ETZ05003.1 - 7.6e-15 55.1 0.0 9.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Beta-lactamase PF00144.24 ETZ05005.1 - 3.4e-09 36.4 0.0 4.1e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase LptD PF04453.14 ETZ05006.1 - 1.4e-27 96.9 0.1 2.9e-27 95.9 0.1 1.6 1 1 0 1 1 1 1 LPS transport system D HTH_Tnp_IS630 PF01710.16 ETZ05007.1 - 2.7e-13 50.0 0.1 3.5e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ETZ05007.1 - 0.00039 20.5 0.1 0.00061 19.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ETZ05007.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 ETZ05007.1 - 0.022 14.7 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn helix UBA_6 PF18039.1 ETZ05007.1 - 0.12 12.3 0.9 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain DDE_3 PF13358.6 ETZ05008.1 - 0.0043 16.8 0.0 0.0047 16.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 ETZ05009.1 - 2.1e-05 24.2 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ05009.1 - 0.0068 16.5 0.0 0.0094 16.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ETZ05009.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 ETZ05009.1 - 0.037 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 ETZ05009.1 - 0.095 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 ETZ05009.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_psq PF05225.16 ETZ05009.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Memo PF01875.17 ETZ05010.1 - 0.082 12.0 0.9 3.5 6.7 0.0 2.4 2 1 0 2 2 2 0 Memo-like protein DUF3847 PF12958.7 ETZ05010.1 - 0.1 12.8 0.1 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) Prok-RING_2 PF14445.6 ETZ05010.1 - 0.12 12.5 0.3 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Met_gamma_lyase PF06838.11 ETZ05011.1 - 0.012 14.2 0.6 1.6 7.2 0.2 2.3 2 0 0 2 2 2 0 Methionine gamma-lyase DUF1419 PF07215.11 ETZ05011.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) CAP_N PF01213.19 ETZ05011.1 - 0.28 10.6 3.3 0.45 10.0 0.5 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Acyltransferase PF01553.21 ETZ05012.1 - 4.1e-17 62.1 0.1 6.4e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase MMR_HSR1 PF01926.23 ETZ05013.1 - 7.6e-22 77.6 0.2 1.4e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ05013.1 - 1.5e-11 44.1 0.0 2.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETZ05013.1 - 8.5e-10 38.8 0.1 0.00026 20.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ETZ05013.1 - 2e-09 37.7 1.3 4.4e-05 23.6 0.1 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 ETZ05013.1 - 2.4e-08 33.8 0.0 3.4e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KH_2 PF07650.17 ETZ05013.1 - 2e-07 30.7 0.7 1.8e-06 27.7 0.1 2.6 3 0 0 3 3 3 1 KH domain cobW PF02492.19 ETZ05013.1 - 1.3e-05 24.9 0.2 0.0015 18.2 0.0 2.2 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 ETZ05013.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 ETZ05013.1 - 0.0036 16.7 0.1 0.0065 15.9 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ETZ05013.1 - 0.034 14.3 2.3 0.048 13.9 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ETZ05013.1 - 0.054 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETZ05013.1 - 0.1 13.1 0.1 0.23 11.9 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Ribonucleas_3_3 PF14622.6 ETZ05014.1 - 1.4e-17 64.0 0.0 2.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 ETZ05014.1 - 7.3e-17 61.8 0.6 1.4e-16 60.9 0.1 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 ETZ05014.1 - 6.8e-14 52.4 0.0 3.3e-13 50.1 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease III domain DND1_DSRM PF14709.7 ETZ05014.1 - 1.8e-08 34.5 2.5 1.4e-07 31.7 2.0 2.4 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 ATP-synt_DE_N PF02823.16 ETZ05015.1 - 1.7e-07 31.0 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_ab PF00006.25 ETZ05016.1 - 2.9e-61 206.8 0.0 4e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ETZ05016.1 - 4.8e-19 68.6 0.9 1.1e-18 67.5 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ETZ05016.1 - 0.019 14.3 0.4 0.08 12.3 0.1 2.1 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 ETZ05016.1 - 0.037 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ETZ05016.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 ETZ05016.1 - 0.095 11.9 0.8 0.16 11.1 0.3 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 ETZ05016.1 - 0.11 12.0 0.1 1.2 8.7 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ETZ05016.1 - 0.14 12.5 0.2 0.29 11.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AOX PF01786.17 ETZ05017.1 - 1.6e-63 214.2 0.0 1.9e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase HTH_25 PF13413.6 ETZ05017.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain tRNA-synt_2b PF00587.25 ETZ05018.1 - 6.5e-39 133.7 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETZ05018.1 - 3e-12 46.5 0.2 6e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ETZ05018.1 - 1.5e-11 44.2 0.0 3.8e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain IF3_N PF05198.16 ETZ05019.1 - 4.8e-28 97.2 1.1 3.8e-27 94.3 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 ETZ05019.1 - 7.8e-19 67.4 0.3 1.4e-18 66.6 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Mur_ligase_M PF08245.12 ETZ05020.1 - 5.5e-29 101.5 0.0 1.3e-28 100.3 0.0 1.6 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase PF01225.25 ETZ05020.1 - 5e-09 36.4 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 ETZ05020.1 - 1.3e-08 34.9 0.0 3.8e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain tRNA-synt_2b PF00587.25 ETZ05021.1 - 5.3e-35 121.0 0.0 9.5e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETZ05021.1 - 6.7e-11 42.2 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain AAA_35 PF14516.6 ETZ05021.1 - 0.084 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain CTP_transf_3 PF02348.19 ETZ05022.1 - 1.2e-22 80.9 0.0 1.7e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 ETZ05022.1 - 8.7e-06 26.2 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain MurJ PF03023.14 ETZ05023.1 - 1.8e-65 221.4 25.4 2.2e-65 221.0 25.4 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ RNase_T PF00929.24 ETZ05026.1 - 7e-32 111.3 0.0 1e-31 110.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ETZ05026.1 - 0.0005 20.1 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 ETZ05026.1 - 0.0093 15.7 0.0 0.16 11.7 0.0 2.5 1 1 1 2 2 2 1 3'-5' exonuclease TLC PF03219.14 ETZ05027.1 - 1.5e-149 498.9 12.9 1.8e-149 498.7 12.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter PDR_CDR PF06422.12 ETZ05027.1 - 3.4 7.6 5.4 0.8 9.6 0.8 2.4 2 0 0 2 2 2 0 CDR ABC transporter SPOUT_MTase PF02590.17 ETZ05028.1 - 9.8e-26 90.6 0.0 2.2e-25 89.5 0.0 1.5 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase Lon_C PF05362.13 ETZ05029.1 - 1.3e-71 240.3 0.4 2.7e-71 239.3 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ETZ05029.1 - 1e-22 81.0 0.0 1.5e-21 77.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 ETZ05029.1 - 6.4e-14 52.3 2.1 1.6e-13 51.1 2.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 ETZ05029.1 - 3.2e-09 36.9 0.0 2.1e-08 34.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETZ05029.1 - 2.7e-08 34.1 0.1 2.3e-07 31.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ETZ05029.1 - 4.5e-06 26.5 0.0 0.0001 22.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 ETZ05029.1 - 5.1e-05 22.4 0.0 0.00013 21.0 0.0 1.6 1 1 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 ETZ05029.1 - 7.3e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 ETZ05029.1 - 0.00024 21.5 2.1 0.00035 21.0 0.1 2.3 3 1 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 ETZ05029.1 - 0.00026 21.6 0.1 0.0014 19.2 0.1 2.3 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 ETZ05029.1 - 0.00061 20.1 3.1 0.0048 17.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_3 PF07726.11 ETZ05029.1 - 0.0012 18.7 0.0 0.03 14.2 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ETZ05029.1 - 0.0031 17.3 0.2 0.0076 16.0 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ETZ05029.1 - 0.0034 17.7 0.1 0.078 13.4 0.0 3.1 4 0 0 4 4 2 1 RNA helicase TsaE PF02367.17 ETZ05029.1 - 0.0042 17.1 1.4 0.05 13.6 0.0 3.0 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ETZ05029.1 - 0.0042 16.8 0.0 0.015 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETZ05029.1 - 0.006 16.3 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ETZ05029.1 - 0.021 14.8 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 ETZ05029.1 - 0.029 14.5 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 ETZ05029.1 - 0.029 14.9 4.0 0.045 14.3 0.0 3.1 3 0 0 3 3 3 0 ABC transporter DEAD PF00270.29 ETZ05029.1 - 0.08 12.7 0.1 1 9.1 0.0 2.9 2 1 1 3 3 3 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 ETZ05029.1 - 0.092 12.4 0.1 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 ETZ05029.1 - 0.092 12.7 0.6 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.6 ETZ05029.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.8 4 1 0 4 4 4 0 AAA domain SMC_N PF02463.19 ETZ05029.1 - 0.13 11.7 0.0 14 5.0 0.0 2.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ETZ05029.1 - 0.15 12.0 1.4 0.52 10.2 0.0 2.4 2 1 1 3 3 3 0 RsgA GTPase AAA_19 PF13245.6 ETZ05029.1 - 0.19 12.0 1.3 0.69 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain Flagellar_rod PF05149.12 ETZ05029.1 - 0.6 9.5 13.1 5.5 6.4 7.6 2.3 2 0 0 2 2 2 0 Paraflagellar rod protein AAA_11 PF13086.6 ETZ05029.1 - 1.7 8.4 0.0 1.7 8.4 0.0 2.6 1 1 1 2 2 1 0 AAA domain Osmo_CC PF08946.10 ETZ05029.1 - 6.5 7.1 9.1 69 3.8 0.5 3.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Inositol_P PF00459.25 ETZ05030.1 - 5e-48 164.0 0.0 6.4e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family NUDIX PF00293.28 ETZ05031.1 - 3.8e-20 72.2 0.0 5.1e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1g PF09334.11 ETZ05033.1 - 1.6e-103 346.5 0.5 2.7e-63 214.1 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ETZ05033.1 - 5.3e-29 100.9 1.9 1.1e-19 70.1 0.0 3.4 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ETZ05033.1 - 2.6e-16 59.9 0.0 6.5e-08 32.3 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ETZ05033.1 - 0.0031 16.5 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) Anticodon_1 PF08264.13 ETZ05033.1 - 0.02 14.8 0.5 0.47 10.4 0.1 2.9 3 0 0 3 3 3 0 Anticodon-binding domain of tRNA DUF1441 PF07278.11 ETZ05033.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) tRNA-synt_1d PF00750.19 ETZ05033.1 - 0.16 10.9 0.1 0.38 9.7 0.1 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (R) Radical_SAM PF04055.21 ETZ05034.1 - 4.8e-16 59.6 0.0 7.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 ETZ05034.1 - 0.15 12.1 0.4 0.46 10.6 0.4 1.9 1 1 0 1 1 1 0 HemN C-terminal domain Sec16 PF12932.7 ETZ05034.1 - 0.17 12.4 0.1 0.42 11.2 0.1 1.8 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region MazG PF03819.17 ETZ05036.1 - 0.0089 16.2 0.2 0.016 15.4 0.2 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain dUTPase_2 PF08761.11 ETZ05036.1 - 0.079 13.1 1.8 0.34 11.0 1.8 1.9 1 1 0 1 1 1 0 dUTPase CTP_synth_N PF06418.14 ETZ05037.1 - 9.9e-101 336.5 0.0 1.6e-100 335.8 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ETZ05037.1 - 5e-50 169.9 0.0 8.3e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ETZ05037.1 - 1.3e-09 38.1 0.3 3.4e-08 33.5 0.3 2.7 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 ETZ05037.1 - 0.003 17.6 0.0 0.0054 16.8 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GATase_3 PF07685.14 ETZ05037.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Herpes_UL1 PF05259.11 ETZ05037.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein L PCRF PF03462.18 ETZ05039.1 - 6.1e-50 169.8 0.1 1.2e-49 168.8 0.0 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ETZ05039.1 - 4e-41 139.6 0.2 6.6e-41 138.9 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain Aminotran_5 PF00266.19 ETZ05040.1 - 4.4e-73 246.4 0.0 5.6e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETZ05040.1 - 3.9e-05 23.1 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ETZ05040.1 - 0.0028 17.0 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cir_N PF10197.9 ETZ05040.1 - 0.4 10.9 1.4 0.71 10.1 1.4 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR NifU_N PF01592.16 ETZ05041.1 - 3e-48 163.2 0.3 3.3e-48 163.1 0.3 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Proteasome PF00227.26 ETZ05041.1 - 0.076 12.5 0.6 0.12 11.8 0.1 1.5 2 0 0 2 2 2 0 Proteasome subunit Ldh_1_N PF00056.23 ETZ05042.1 - 3.6e-30 104.9 0.0 5.3e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ETZ05042.1 - 3.2e-19 69.5 0.0 4.9e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3HCDH_N PF02737.18 ETZ05042.1 - 0.0051 16.7 0.1 0.0095 15.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ETZ05042.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HlyD_D23 PF16576.5 ETZ05043.1 - 1.6e-08 34.0 2.2 2.8e-08 33.3 2.2 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ETZ05043.1 - 2.5e-08 34.6 1.1 2.6e-07 31.3 0.3 2.5 2 0 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ETZ05043.1 - 0.0032 17.3 0.1 0.0032 17.3 0.1 2.7 3 0 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ETZ05043.1 - 0.0048 16.7 5.8 0.036 13.9 0.1 3.8 3 1 1 4 4 4 1 Biotin-requiring enzyme Alkyl_sulf_dimr PF14863.6 ETZ05043.1 - 0.049 14.1 0.1 0.61 10.5 0.0 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation T2SSB PF16537.5 ETZ05043.1 - 0.17 11.5 1.7 0.29 10.7 0.1 2.3 2 1 1 3 3 3 0 Type II secretion system protein B ACR_tran PF00873.19 ETZ05044.1 - 1.7e-244 813.9 6.5 2.1e-244 813.7 6.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 ETZ05044.1 - 1.9e-15 56.6 27.6 7.9e-11 41.5 7.0 2.9 3 0 0 3 3 3 2 MMPL family Ribosomal_L22 PF00237.19 ETZ05044.1 - 0.19 12.0 0.0 1.1 9.5 0.0 2.3 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e SecD_SecF PF02355.16 ETZ05044.1 - 0.35 10.2 30.0 0.13 11.6 14.2 2.3 2 0 0 2 2 2 0 Protein export membrane protein tRNA-synt_2d PF01409.20 ETZ05045.1 - 2.6e-91 305.4 0.0 3.5e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 ETZ05045.1 - 1.2e-14 54.0 7.8 1.9e-14 53.3 7.8 1.3 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3208 PF11482.8 ETZ05045.1 - 0.082 13.2 0.4 56 4.1 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3208) Tho2 PF11262.8 ETZ05045.1 - 0.1 11.8 0.4 0.16 11.2 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LZ_Tnp_IS66 PF13007.7 ETZ05045.1 - 0.44 11.4 2.2 0.89 10.4 2.2 1.5 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain SBP_bac_8 PF13416.6 ETZ05050.1 - 1.2e-25 90.9 0.0 1.5e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ETZ05050.1 - 3e-15 56.3 0.1 4.4e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ETZ05050.1 - 9.5e-13 48.8 0.0 1.2e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ETZ05050.1 - 0.00027 20.8 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein HTH_Tnp_IS630 PF01710.16 ETZ05052.1 - 0.0013 18.8 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Transposase TAL_FSA PF00923.19 ETZ05053.1 - 4e-46 157.6 0.0 4.8e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF2232 PF09991.9 ETZ05053.1 - 0.019 14.2 0.6 0.025 13.8 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) tRNA-synt_2 PF00152.20 ETZ05055.1 - 2.3e-95 319.3 0.0 2.8e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 ETZ05055.1 - 1.3e-17 63.8 0.0 1.2e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.25 ETZ05055.1 - 1.6e-12 47.3 0.0 2.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ETZ05055.1 - 0.011 15.3 0.0 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 ETZ05055.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_C26 PF07722.13 ETZ05056.1 - 7.4e-54 182.8 0.0 9e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ETZ05056.1 - 2.6e-16 59.9 0.1 4.1e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ETZ05056.1 - 0.0039 16.8 0.4 0.0053 16.4 0.4 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MlaC PF05494.12 ETZ05057.1 - 1.2e-12 47.9 0.1 1.7e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 MlaC protein DUF3161 PF11362.8 ETZ05057.1 - 0.032 14.2 0.2 0.073 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) T2SSE PF00437.20 ETZ05058.1 - 8.2e-66 221.9 0.1 1.5e-65 221.0 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein T2SSE_N PF05157.15 ETZ05058.1 - 1.5e-09 38.1 0.1 3e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_14 PF13173.6 ETZ05058.1 - 6.1e-05 23.1 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ05058.1 - 0.00021 21.7 0.1 0.00056 20.3 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETZ05058.1 - 0.001 19.6 0.0 0.0034 17.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 ETZ05058.1 - 0.0012 18.8 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 ETZ05058.1 - 0.0016 18.7 0.0 0.0057 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ETZ05058.1 - 0.0042 17.6 0.1 0.011 16.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ETZ05058.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ETZ05058.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 ETZ05058.1 - 0.009 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETZ05058.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETZ05058.1 - 0.046 13.7 0.1 0.094 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ05058.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 ETZ05058.1 - 0.059 13.7 1.4 0.14 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 ETZ05058.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 ETZ05058.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 ETZ05058.1 - 0.19 11.6 0.6 5.2 6.9 0.1 2.5 1 1 1 2 2 2 0 NTPase T2SSF PF00482.23 ETZ05059.1 - 3.5e-21 75.5 0.1 5.4e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F IRS PF02174.17 ETZ05062.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 PTB domain (IRS-1 type) H_PPase PF03030.16 ETZ05063.1 - 1.7e-246 820.0 42.8 2e-246 819.8 42.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Zip PF02535.22 ETZ05064.1 - 0.12 11.5 3.5 0.19 10.9 3.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 ETZ05064.1 - 1.2 8.0 3.6 1.9 7.3 3.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DAHP_synth_1 PF00793.20 ETZ05066.1 - 3.6e-62 209.7 0.0 4.3e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PEP_mutase PF13714.6 ETZ05066.1 - 0.017 14.6 0.0 0.11 11.9 0.0 2.1 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Glycos_transf_1 PF00534.20 ETZ05067.1 - 3.2e-28 98.4 0.0 4.7e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ05067.1 - 1.2e-21 77.6 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ05067.1 - 5.4e-08 33.0 0.0 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ETZ05067.1 - 4.2e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETZ05067.1 - 0.011 16.2 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Sod_Fe_C PF02777.18 ETZ05068.1 - 1.5e-31 108.6 2.9 3.2e-31 107.5 0.5 2.3 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ETZ05068.1 - 1.2e-22 80.2 1.8 1.2e-22 80.2 1.8 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Glycos_transf_N PF04413.16 ETZ05069.1 - 3.8e-38 130.9 0.0 6.1e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF5072 PF16807.5 ETZ05069.1 - 0.11 12.6 0.3 0.25 11.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) Alpha_E1_glycop PF01589.16 ETZ05071.1 - 0.2 10.3 0.0 0.22 10.1 0.0 1.0 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein DDE_3 PF13358.6 ETZ05072.1 - 1.2e-12 47.8 0.0 1.4e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M24 PF00557.24 ETZ05073.1 - 2.3e-40 138.5 0.0 3.1e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ETZ05073.1 - 4.3e-16 58.7 0.2 8.8e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 QIL1 PF15884.5 ETZ05073.1 - 0.6 10.8 2.7 0.52 11.0 0.6 2.0 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 PD40 PF07676.12 ETZ05074.1 - 9.8e-15 54.1 1.1 1.6e-07 31.1 0.2 3.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat TolB_N PF04052.13 ETZ05074.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 TolB amino-terminal domain DPPIV_N PF00930.21 ETZ05074.1 - 0.0029 16.4 0.0 0.86 8.3 0.0 2.6 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 ETZ05074.1 - 0.063 13.0 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain POTRA PF07244.15 ETZ05076.1 - 2.4e-37 127.4 10.2 1.7e-11 44.5 0.5 5.5 5 0 0 5 5 5 5 Surface antigen variable number repeat Bac_surface_Ag PF01103.23 ETZ05076.1 - 5e-37 128.1 9.4 7e-37 127.6 9.4 1.2 1 0 0 1 1 1 1 Surface antigen POTRA_2 PF08479.11 ETZ05076.1 - 3.2e-06 26.9 0.5 0.034 14.0 0.0 3.9 4 0 0 4 4 4 2 POTRA domain, ShlB-type POTRA_1 PF08478.10 ETZ05076.1 - 0.0038 17.5 0.5 9.8 6.6 0.0 3.8 3 1 1 4 4 4 2 POTRA domain, FtsQ-type HTH_Tnp_IS630 PF01710.16 ETZ05078.1 - 0.00057 19.9 0.3 0.00061 19.8 0.3 1.1 1 0 0 1 1 1 1 Transposase Lip_A_acyltrans PF03279.13 ETZ05079.1 - 2.3e-47 161.6 0.2 2.7e-47 161.4 0.2 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Guanylate_cyc_2 PF09778.9 ETZ05079.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Guanylylate cyclase TIR_2 PF13676.6 ETZ05079.1 - 0.04 14.5 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain Creatininase PF02633.14 ETZ05079.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Creatinine amidohydrolase CsgA PF17334.2 ETZ05080.1 - 0.074 13.8 0.1 0.13 13.0 0.1 1.4 1 0 0 1 1 1 0 Minor curli fiber component A P3A PF08727.11 ETZ05082.1 - 0.047 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Poliovirus 3A protein like DDE_Tnp_1_2 PF13586.6 ETZ05083.1 - 2.5e-07 31.0 0.0 2.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ETZ05083.1 - 0.0013 18.4 0.1 0.0013 18.4 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DUF374 PF04028.13 ETZ05084.1 - 6.1e-25 86.6 0.1 1e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF374) DUF21 PF01595.20 ETZ05085.1 - 6.4e-30 104.2 5.3 9.2e-30 103.6 5.3 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ETZ05085.1 - 6e-17 61.8 0.0 3e-08 34.0 0.0 3.4 3 0 0 3 3 3 2 CBS domain CorC_HlyC PF03471.17 ETZ05085.1 - 2.4e-15 56.3 0.0 5.6e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain DUF3433 PF11915.8 ETZ05085.1 - 0.56 10.7 6.0 0.056 13.9 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) SKI PF01202.22 ETZ05086.1 - 3e-31 108.7 0.0 4.1e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ETZ05086.1 - 1e-08 35.8 0.1 4.1e-07 30.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ETZ05086.1 - 1.4e-05 25.3 0.0 0.00011 22.4 0.0 1.9 1 1 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 ETZ05086.1 - 8.3e-05 23.0 0.1 0.00061 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ETZ05086.1 - 0.00035 20.7 0.0 0.00084 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ05086.1 - 0.0004 20.8 0.3 0.0012 19.3 0.1 2.0 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ05086.1 - 0.0017 18.6 0.1 0.0062 16.8 0.0 1.9 1 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ETZ05086.1 - 0.003 18.1 0.0 0.005 17.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter CoaE PF01121.20 ETZ05086.1 - 0.0033 17.1 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_24 PF13479.6 ETZ05086.1 - 0.0082 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETZ05086.1 - 0.016 15.6 0.1 0.022 15.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 ETZ05086.1 - 0.027 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ETZ05086.1 - 0.034 13.3 0.2 0.075 12.2 0.2 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 ETZ05086.1 - 0.05 13.8 0.0 0.078 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ETZ05086.1 - 0.053 13.3 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 ETZ05086.1 - 0.092 12.6 0.1 0.66 9.8 0.0 2.1 1 1 1 2 2 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 ETZ05086.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase tRNA_lig_kinase PF08303.11 ETZ05086.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain Cytidylate_kin PF02224.18 ETZ05086.1 - 0.21 11.3 0.0 0.49 10.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase GRP PF07172.11 ETZ05087.1 - 0.045 14.4 0.5 0.047 14.4 0.5 1.1 1 0 0 1 1 1 0 Glycine rich protein family CfAFP PF05264.11 ETZ05087.1 - 0.058 13.4 0.0 0.058 13.4 0.0 1.0 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF4148 PF13663.6 ETZ05087.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Acetyltransf_11 PF13720.6 ETZ05088.1 - 2.6e-14 53.4 0.1 4.2e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 ETZ05088.1 - 3.3e-14 51.9 30.1 0.00026 20.6 0.7 6.9 4 2 4 8 8 8 7 Bacterial transferase hexapeptide (six repeats) DDE_3 PF13358.6 ETZ05089.1 - 1.1e-06 28.5 0.0 1.2e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease OEP PF02321.18 ETZ05090.1 - 1.4e-29 103.3 6.2 9.6e-15 54.9 1.9 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein LRR_3 PF07725.12 ETZ05090.1 - 0.039 13.8 0.8 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 Leucine Rich Repeat DUF2497 PF10691.9 ETZ05091.1 - 0.08 13.4 2.7 8.5 6.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) Trigger_N PF05697.13 ETZ05093.1 - 3.7e-10 40.3 0.4 1.4e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) CLP_protease PF00574.23 ETZ05094.1 - 4e-80 268.0 0.0 4.6e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF5429 PF17494.2 ETZ05094.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5429) AAA_2 PF07724.14 ETZ05095.1 - 1.1e-47 162.3 0.1 1.6e-47 161.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 ETZ05095.1 - 8.2e-20 70.4 4.4 2.2e-19 69.0 4.4 1.8 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 ETZ05095.1 - 8.7e-18 65.0 0.1 3.1e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ETZ05095.1 - 3e-12 46.4 0.4 3e-12 46.4 0.4 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 ETZ05095.1 - 3.7e-06 26.2 0.1 6.1e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 ETZ05095.1 - 1.2e-05 25.3 0.1 0.00017 21.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETZ05095.1 - 4e-05 23.9 0.2 0.00016 22.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ETZ05095.1 - 4.4e-05 23.0 0.1 0.0083 15.5 0.1 3.0 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ETZ05095.1 - 4.4e-05 23.2 0.1 0.00075 19.2 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 ETZ05095.1 - 7.3e-05 22.6 0.3 0.0003 20.6 0.3 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ETZ05095.1 - 0.00026 20.5 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 ETZ05095.1 - 0.00063 19.8 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETZ05095.1 - 0.0033 17.6 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ETZ05095.1 - 0.0044 16.3 0.2 0.019 14.2 0.0 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 ETZ05095.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 ETZ05095.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 ETZ05095.1 - 0.023 15.1 0.2 0.074 13.4 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 ETZ05095.1 - 0.03 13.6 0.1 0.061 12.6 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 ETZ05095.1 - 0.038 14.5 0.1 0.097 13.2 0.0 1.8 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.12 ETZ05095.1 - 0.045 13.7 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ETZ05095.1 - 0.046 14.1 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 RNA helicase SKI PF01202.22 ETZ05095.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase ATPase PF06745.13 ETZ05095.1 - 0.064 12.6 1.6 0.88 8.9 0.1 2.3 1 1 0 2 2 2 0 KaiC AAA_24 PF13479.6 ETZ05095.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ETZ05095.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 ETZ05095.1 - 0.099 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ETZ05095.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 ETZ05095.1 - 0.13 11.6 0.1 0.34 10.3 0.1 1.6 1 0 0 1 1 1 0 Isopentenyl transferase AAA_18 PF13238.6 ETZ05095.1 - 0.13 12.8 0.1 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 ETZ05095.1 - 0.15 11.9 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SBP_bac_5 PF00496.22 ETZ05096.1 - 3.9e-46 157.7 0.0 5.5e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_L33 PF00471.20 ETZ05097.1 - 6e-11 42.6 1.4 7.6e-11 42.3 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 LRR_4 PF12799.7 ETZ05098.1 - 4e-09 36.6 0.2 0.00068 20.0 0.0 4.0 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ETZ05098.1 - 0.018 14.6 0.4 0.12 11.9 0.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeat S4 PF01479.25 ETZ05098.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 S4 domain HTH_23 PF13384.6 ETZ05099.1 - 0.00018 21.2 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ05099.1 - 0.025 14.7 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 ETZ05099.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 ETZ05099.1 - 0.036 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 ETZ05099.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DnaJ PF00226.31 ETZ05100.1 - 2.1e-06 27.7 0.0 5.4e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain DUF1996 PF09362.10 ETZ05100.1 - 0.0018 18.3 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HSP70 PF00012.20 ETZ05101.1 - 3.5e-99 332.7 0.0 3.5e-95 319.4 0.0 3.0 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ETZ05101.1 - 2.8e-12 46.1 0.0 3.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 ETZ05101.1 - 0.075 12.5 0.0 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NAD_binding_3 PF03447.16 ETZ05101.1 - 0.079 13.6 0.0 0.29 11.8 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DUF3730 PF12530.8 ETZ05101.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) RNA_pol_Rpb6 PF01192.22 ETZ05102.1 - 1.6e-08 34.3 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DNA_topoisoIV PF00521.20 ETZ05103.1 - 8.4e-140 466.4 0.0 1.3e-139 465.8 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 ETZ05103.1 - 3.2e-66 218.6 4.8 5.3e-12 45.0 0.1 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller DUF2835 PF11197.8 ETZ05103.1 - 0.00057 19.6 0.1 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2835) PriA_C PF18074.1 ETZ05104.1 - 9e-19 68.1 0.1 2.1e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain DEAD PF00270.29 ETZ05104.1 - 2.9e-13 49.9 0.0 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ETZ05104.1 - 2.6e-12 47.1 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PriA_3primeBD PF17764.1 ETZ05104.1 - 7.4e-12 45.0 0.0 1.7e-10 40.6 0.0 2.8 3 0 0 3 3 3 1 3′ DNA-binding domain (3′BD) PriA_CRR PF18319.1 ETZ05104.1 - 9.4e-08 31.9 4.1 3.8e-07 30.0 4.1 2.1 1 0 0 1 1 1 1 PriA DNA helicase Cys-rich region (CRR) domain Helicase_C PF00271.31 ETZ05104.1 - 1.1e-07 32.2 0.1 8e-05 23.0 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.23 ETZ05104.1 - 0.00064 18.5 0.3 0.0066 15.2 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain TrwB_AAD_bind PF10412.9 ETZ05104.1 - 0.026 13.4 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 ETZ05104.1 - 0.072 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Phage_integrase PF00589.22 ETZ05105.1 - 2.3e-31 108.9 0.0 4.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ETZ05105.1 - 3.8e-09 36.7 1.2 2.8e-08 33.9 0.2 2.9 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ETZ05105.1 - 1.3e-07 32.0 0.6 3.1e-07 30.8 0.6 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 ETZ05105.1 - 0.0074 16.6 0.1 0.02 15.2 0.1 1.7 1 0 0 1 1 1 1 Phage integrase SAM-like domain Integrase_1 PF12835.7 ETZ05105.1 - 0.02 15.0 0.1 0.16 12.0 0.0 2.5 2 2 0 2 2 2 0 Integrase DIMCO_N PF16844.5 ETZ05105.1 - 0.085 13.2 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF4114 PF13448.6 ETZ05105.1 - 0.13 13.1 0.0 0.28 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) SmpA_OmlA PF04355.13 ETZ05106.1 - 2.8e-07 30.2 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family SIMPL PF04402.14 ETZ05107.1 - 1.1e-17 65.2 1.2 1.4e-17 64.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF3666 PF12408.8 ETZ05107.1 - 0.14 11.4 0.9 0.32 10.2 0.9 1.6 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase SOAR PF16533.5 ETZ05107.1 - 0.15 12.0 4.1 0.64 10.0 0.5 2.6 2 1 1 3 3 3 0 STIM1 Orai1-activating region SIMPL PF04402.14 ETZ05108.1 - 1.4e-14 55.0 0.0 1.8e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) KxDL PF10241.9 ETZ05108.1 - 0.2 11.9 3.5 3.7 7.9 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein SIMPL PF04402.14 ETZ05109.1 - 3.4e-12 47.2 0.0 4.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Sec63 PF02889.16 ETZ05109.1 - 0.0059 15.8 0.1 0.008 15.4 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DUF4178 PF13785.6 ETZ05109.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) Methyltransf_4 PF02390.17 ETZ05110.1 - 3.2e-38 130.9 0.0 3.8e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Peroxidase_ext PF11895.8 ETZ05110.1 - 0.027 14.4 0.0 8.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Fungal peroxidase extension region Methyltransf_12 PF08242.12 ETZ05110.1 - 0.06 14.1 0.0 0.58 10.9 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ05110.1 - 0.09 13.5 0.0 1.6 9.5 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain CagY_M PF07337.11 ETZ05110.1 - 0.11 12.1 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 DC-EC Repeat HTH_Tnp_IS630 PF01710.16 ETZ05111.1 - 8.9e-05 22.5 0.1 9.5e-05 22.4 0.1 1.0 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ETZ05111.1 - 0.0046 17.0 0.0 0.005 16.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain Carboxyl_trans PF01039.22 ETZ05112.1 - 8.1e-16 57.7 0.0 3.1e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Carboxyl transferase domain zf-ACC PF17848.1 ETZ05112.1 - 2.5e-10 40.2 2.7 5.8e-10 39.1 2.7 1.7 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf-UBP PF02148.19 ETZ05112.1 - 0.08 13.3 1.8 0.14 12.5 1.8 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Glutaredoxin2_C PF04399.13 ETZ05113.1 - 0.34 10.8 2.5 0.54 10.1 0.2 2.5 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain BacA PF02673.18 ETZ05114.1 - 1.6e-40 139.4 14.4 2e-40 139.2 14.4 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA LapA_dom PF06305.11 ETZ05114.1 - 0.78 9.6 0.1 0.78 9.6 0.1 3.5 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain BPL_LplA_LipB PF03099.19 ETZ05115.1 - 0.001 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DDE_3 PF13358.6 ETZ05116.1 - 1.8e-08 34.3 0.0 1.8e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4168 PF13767.6 ETZ05117.1 - 0.17 13.1 2.1 0.26 12.5 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) SRP54 PF00448.22 ETZ05119.1 - 5.8e-56 189.2 0.0 1e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ETZ05119.1 - 1.3e-30 106.0 5.7 2.4e-30 105.1 1.9 2.5 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 ETZ05119.1 - 1e-16 60.9 0.3 3.6e-16 59.1 0.3 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 ETZ05119.1 - 5.5e-06 26.7 0.1 2.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 ETZ05119.1 - 2.2e-05 24.5 0.0 0.00018 21.5 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ETZ05119.1 - 3.6e-05 23.6 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ETZ05119.1 - 0.0011 19.5 0.2 0.0043 17.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.6 ETZ05119.1 - 0.0044 16.9 0.9 0.019 14.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETZ05119.1 - 0.013 15.9 0.1 0.036 14.5 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain ArsA_ATPase PF02374.15 ETZ05119.1 - 0.013 14.7 4.7 0.066 12.4 0.1 3.0 2 1 1 3 3 3 0 Anion-transporting ATPase ATPase PF06745.13 ETZ05119.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Arf PF00025.21 ETZ05119.1 - 0.025 14.0 0.2 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2780 PF11075.8 ETZ05119.1 - 0.034 14.3 1.2 19 5.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) hnRNP_Q_AcD PF18360.1 ETZ05119.1 - 0.042 13.8 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain MeaB PF03308.16 ETZ05119.1 - 0.059 12.3 0.1 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 ETZ05119.1 - 0.078 12.7 0.2 0.25 11.1 0.2 1.9 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF5612 PF18462.1 ETZ05119.1 - 0.1 12.4 0.2 6.1 6.6 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5612) AAA_7 PF12775.7 ETZ05119.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 ETZ05119.1 - 0.11 12.0 0.1 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETZ05119.1 - 0.12 12.5 0.6 1.2 9.3 0.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ETZ05119.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 ETZ05120.1 - 3.3e-09 37.2 0.1 3.3e-09 37.2 0.1 1.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Tropomyosin PF00261.20 ETZ05120.1 - 0.0061 16.0 3.0 0.013 14.9 3.0 1.5 1 0 0 1 1 1 1 Tropomyosin Pyr_redox PF00070.27 ETZ05120.1 - 0.062 13.9 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XhlA PF10779.9 ETZ05120.1 - 0.13 12.5 2.1 0.5 10.6 1.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA GTP-bdg_M PF16360.5 ETZ05120.1 - 0.24 12.0 3.4 0.73 10.5 1.9 2.3 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Hexapep PF00132.24 ETZ05121.1 - 3.8e-25 86.6 17.9 4.3e-07 29.4 0.2 5.5 5 0 0 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETZ05121.1 - 8e-08 31.9 20.7 0.016 14.9 1.5 5.6 3 2 2 5 5 5 4 Hexapeptide repeat of succinyl-transferase LpxD PF04613.14 ETZ05121.1 - 1.7e-06 27.7 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD FabA PF07977.13 ETZ05122.1 - 8.9e-36 122.6 0.2 1e-35 122.3 0.2 1.0 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 ETZ05122.1 - 0.00093 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 ETZ05122.1 - 0.0063 16.8 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF5599 PF18141.1 ETZ05122.1 - 0.014 15.6 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) DUF3445 PF11927.8 ETZ05122.1 - 0.074 12.7 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Response_reg PF00072.24 ETZ05123.1 - 6.6e-26 90.7 0.1 1.2e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activat PF00158.26 ETZ05123.1 - 7e-18 64.9 0.1 1.4e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ETZ05123.1 - 1.4e-07 31.7 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 ETZ05123.1 - 0.0002 21.1 0.1 0.00066 19.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family ABC_tran PF00005.27 ETZ05123.1 - 0.0003 21.3 0.4 0.00088 19.8 0.1 1.9 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 ETZ05123.1 - 0.00057 19.9 0.2 0.0013 18.7 0.2 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Roc PF08477.13 ETZ05123.1 - 0.0024 18.1 0.3 0.048 13.9 0.0 2.7 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ETZ05123.1 - 0.0024 17.4 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region SRP54 PF00448.22 ETZ05123.1 - 0.0033 17.1 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain FleQ PF06490.11 ETZ05123.1 - 0.0039 17.6 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ AAA_16 PF13191.6 ETZ05123.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 ETZ05123.1 - 0.007 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ETZ05123.1 - 0.0097 15.1 0.2 0.032 13.4 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.29 ETZ05123.1 - 0.01 16.2 0.0 0.034 14.6 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETZ05123.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ETZ05123.1 - 0.032 14.0 0.4 0.062 13.0 0.4 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ETZ05123.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETZ05123.1 - 0.048 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ETZ05123.1 - 0.067 13.7 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 ETZ05123.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain B12-binding PF02310.19 ETZ05123.1 - 0.083 12.9 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain MCM PF00493.23 ETZ05123.1 - 0.085 11.9 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain HTH_1 PF00126.27 ETZ05123.1 - 0.096 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family IstB_IS21 PF01695.17 ETZ05123.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 ETZ05123.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 ETZ05123.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Apolipoprotein PF01442.18 ETZ05124.1 - 0.0066 16.3 0.5 0.0099 15.8 0.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain vATP-synt_E PF01991.18 ETZ05124.1 - 0.028 13.9 1.9 1 8.7 1.0 2.3 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit YtxH PF12732.7 ETZ05124.1 - 0.13 12.8 0.6 0.36 11.4 0.7 1.8 1 1 0 1 1 1 0 YtxH-like protein Colicin PF01024.19 ETZ05124.1 - 0.18 11.7 0.6 0.52 10.2 0.3 1.8 1 1 1 2 2 2 0 Colicin pore forming domain Apt1 PF10351.9 ETZ05124.1 - 0.39 9.5 11.1 0.59 8.9 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MRI PF15325.6 ETZ05124.1 - 8.7 7.5 15.1 24 6.1 15.1 1.8 1 0 0 1 1 1 0 Modulator of retrovirus infection Bac_transf PF02397.16 ETZ05126.1 - 1.9e-51 174.3 0.0 2.3e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial sugar transferase Na_H_Exchanger PF00999.21 ETZ05128.1 - 4.1e-43 147.6 44.4 5.7e-43 147.2 44.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 ETZ05128.1 - 1.5e-17 63.9 0.0 2.5e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AAA_31 PF13614.6 ETZ05130.1 - 1.2e-57 194.7 0.1 1.5e-57 194.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ETZ05130.1 - 1.2e-26 93.2 0.0 1.7e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ETZ05130.1 - 5.7e-15 55.4 0.0 1.3e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 ETZ05130.1 - 3.6e-11 42.9 0.1 2.8e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 ETZ05130.1 - 5.3e-11 42.4 0.2 3.4e-09 36.5 0.1 2.4 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 ETZ05130.1 - 2.3e-08 33.9 0.0 1.4e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 ETZ05130.1 - 6.1e-07 28.9 1.1 1.8e-06 27.4 0.3 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase SRP54 PF00448.22 ETZ05130.1 - 0.0016 18.1 0.3 0.04 13.6 0.3 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 ETZ05130.1 - 0.0085 15.9 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 ETZ05130.1 - 0.016 14.5 0.3 0.054 12.8 0.1 1.9 2 1 0 2 2 2 0 VirC1 protein BTB_3 PF16017.5 ETZ05130.1 - 0.052 13.7 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain ATP_bind_1 PF03029.17 ETZ05130.1 - 0.075 12.8 0.1 0.22 11.3 0.1 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_trans_1_4 PF13692.6 ETZ05130.1 - 0.1 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 AAA_24 PF13479.6 ETZ05130.1 - 0.19 11.4 0.1 0.4 10.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain FTHFS PF01268.19 ETZ05130.1 - 0.19 9.9 0.5 0.25 9.5 0.5 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase SRP54 PF00448.22 ETZ05131.1 - 7.9e-55 185.5 0.0 1.6e-54 184.6 0.0 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 ETZ05131.1 - 6.7e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETZ05131.1 - 1.2e-05 25.8 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETZ05131.1 - 0.00013 22.3 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 ETZ05131.1 - 0.00037 20.1 0.0 0.0036 16.9 0.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 ETZ05131.1 - 0.00058 19.2 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ETZ05131.1 - 0.0024 17.8 0.0 0.0069 16.3 0.0 1.8 2 0 0 2 2 1 1 NACHT domain AAA_28 PF13521.6 ETZ05131.1 - 0.003 17.8 0.3 0.0093 16.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ETZ05131.1 - 0.0085 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 ETZ05131.1 - 0.01 15.9 0.2 0.038 14.1 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 ETZ05131.1 - 0.011 15.8 0.0 0.078 13.0 0.0 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 ETZ05131.1 - 0.012 16.1 0.1 0.025 15.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 ETZ05131.1 - 0.017 15.6 0.0 0.053 13.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ETZ05131.1 - 0.018 15.2 0.4 0.043 14.0 0.2 1.8 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ETZ05131.1 - 0.022 15.3 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 ETZ05131.1 - 0.023 14.2 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Helicase_RecD PF05127.14 ETZ05131.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Helicase AAA_14 PF13173.6 ETZ05131.1 - 0.031 14.3 0.1 0.27 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ETZ05131.1 - 0.041 13.8 0.3 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase TBPIP PF07106.13 ETZ05131.1 - 0.079 12.9 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DLIC PF05783.11 ETZ05131.1 - 0.11 11.3 0.0 6.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) NTPase_1 PF03266.15 ETZ05131.1 - 0.13 12.2 0.1 0.71 9.8 0.1 2.0 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.6 ETZ05131.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RrnaAD PF00398.20 ETZ05132.1 - 1.3e-41 142.5 0.0 1.4e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase HTH_Tnp_IS630 PF01710.16 ETZ05133.1 - 0.012 15.7 0.5 0.013 15.5 0.5 1.1 1 0 0 1 1 1 0 Transposase DASH_Dad4 PF08650.10 ETZ05133.1 - 0.046 13.7 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 SecA_DEAD PF07517.14 ETZ05133.1 - 0.13 11.6 0.1 0.14 11.4 0.1 1.0 1 0 0 1 1 1 0 SecA DEAD-like domain Pyr_redox_2 PF07992.14 ETZ05136.1 - 1.1e-24 87.2 0.0 1.3e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETZ05136.1 - 7.5e-22 77.9 0.0 5.7e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETZ05136.1 - 5.4e-10 39.7 0.6 9e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETZ05136.1 - 1.1e-07 30.6 0.4 2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 ETZ05136.1 - 1e-06 27.8 0.4 0.0015 17.3 0.4 3.0 2 1 1 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 ETZ05136.1 - 0.00025 20.3 0.3 0.0041 16.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ETZ05136.1 - 0.00044 19.7 0.0 0.046 13.1 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETZ05136.1 - 0.00072 18.9 0.8 0.81 8.9 0.7 2.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 ETZ05136.1 - 0.0022 17.6 0.9 2.3 7.7 0.0 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ETZ05136.1 - 0.0029 18.0 0.1 0.035 14.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ETZ05136.1 - 0.0035 17.5 2.2 0.0059 16.8 0.2 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETZ05136.1 - 0.0044 16.3 0.1 0.065 12.5 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Oxidored_nitro PF00148.19 ETZ05136.1 - 0.014 14.2 0.0 0.025 13.3 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase FAD_binding_2 PF00890.24 ETZ05136.1 - 0.059 12.5 1.4 1.9 7.4 0.1 3.0 2 1 0 3 3 3 0 FAD binding domain ELFV_dehydrog PF00208.21 ETZ05136.1 - 0.21 11.3 0.0 1.5 8.5 0.0 2.1 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zip PF02535.22 ETZ05137.1 - 0.087 12.0 0.5 0.07 12.3 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ETZ05137.1 - 7.9 5.1 10.6 14 4.3 10.6 1.3 1 0 0 1 1 1 0 Presenilin IPPT PF01715.17 ETZ05138.1 - 8e-50 169.8 0.0 1e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 ETZ05138.1 - 0.00066 19.1 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 ETZ05138.1 - 0.033 14.4 0.0 0.069 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AP3D1 PF06375.11 ETZ05139.1 - 0.0022 18.2 3.8 0.0027 18.0 3.8 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SR-25 PF10500.9 ETZ05139.1 - 0.0048 16.5 6.4 0.0056 16.3 6.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 ETZ05139.1 - 0.026 14.2 3.4 0.035 13.8 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NST1 PF13945.6 ETZ05139.1 - 0.51 10.4 6.5 0.81 9.8 6.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Nucleo_P87 PF07267.11 ETZ05139.1 - 0.82 8.5 3.0 0.91 8.3 3.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4096 PF13340.6 ETZ05140.1 - 1.2e-17 63.9 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Asn_synthase PF00733.21 ETZ05141.1 - 4e-90 303.1 0.0 4.8e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ETZ05141.1 - 2.5e-37 127.5 0.0 4.5e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETZ05141.1 - 3.7e-34 117.8 0.0 1.9e-33 115.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETZ05141.1 - 2.8e-06 26.9 0.0 5.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ETZ05141.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 ETZ05141.1 - 0.079 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Transketolase_N PF00456.21 ETZ05142.1 - 1.3e-114 382.6 0.0 1.9e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETZ05142.1 - 1.2e-38 132.6 0.0 3.1e-38 131.2 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 ETZ05142.1 - 1.3e-06 27.8 0.0 0.0002 20.7 0.0 2.6 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ETZ05142.1 - 2.8e-05 23.2 0.0 5.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ETZ05142.1 - 0.011 15.5 0.0 0.054 13.3 0.0 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 ETZ05142.1 - 0.017 15.0 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Transketolase, C-terminal domain Glyco_hydro_63N PF16923.5 ETZ05142.1 - 0.05 13.7 0.1 0.05 13.7 0.1 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 N-terminal domain Polysacc_deac_1 PF01522.21 ETZ05143.1 - 5.2e-27 94.2 0.0 1.4e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETZ05143.1 - 0.0044 16.7 0.0 0.038 13.6 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) 3H PF02829.14 ETZ05143.1 - 0.031 14.6 0.8 0.39 11.0 0.2 2.2 2 0 0 2 2 2 0 3H domain Glyco_hydro_57 PF03065.15 ETZ05143.1 - 0.096 11.9 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 MFS_1 PF07690.16 ETZ05144.1 - 0.0087 15.0 51.9 0.006 15.6 25.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Ubie_methyltran PF01209.18 ETZ05145.1 - 5.8e-45 153.4 0.0 6.4e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ETZ05145.1 - 2e-11 44.4 0.0 2.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ05145.1 - 5.9e-11 42.9 0.0 8.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ05145.1 - 1.6e-06 28.0 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ05145.1 - 0.00023 21.1 0.0 0.00045 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ05145.1 - 0.0011 19.7 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETZ05145.1 - 0.17 11.4 0.0 0.54 9.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain MarC PF01914.17 ETZ05146.1 - 2.4e-34 118.5 11.6 2.7e-34 118.3 11.6 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein 4HB_MCP_1 PF12729.7 ETZ05146.1 - 7.8 6.0 5.3 2.2 7.8 1.7 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DapB_C PF05173.14 ETZ05147.1 - 2.5e-24 85.6 0.0 3.8e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 ETZ05147.1 - 2.7e-05 24.3 0.1 0.00033 20.8 0.1 2.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Fe-S_biosyn PF01521.20 ETZ05148.1 - 4.5e-16 59.0 0.1 5.2e-16 58.8 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis G3P_acyltransf PF02660.15 ETZ05149.1 - 2.9e-43 147.7 18.7 3.5e-43 147.5 18.7 1.1 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase DDE_Tnp_1_2 PF13586.6 ETZ05150.1 - 3.4e-07 30.5 1.3 8.1e-07 29.3 1.3 1.7 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ETZ05150.1 - 0.00016 21.4 3.2 0.00059 19.5 3.1 1.8 1 1 0 1 1 1 1 Transposase DDE domain DUF4455 PF14643.6 ETZ05150.1 - 0.027 13.2 0.5 0.033 12.9 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) OSCP PF00213.18 ETZ05150.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit FtsX PF02687.21 ETZ05151.1 - 1.8e-06 28.3 5.0 1.8e-06 28.3 5.0 3.2 3 0 0 3 3 3 1 FtsX-like permease family Linker_histone PF00538.19 ETZ05151.1 - 0.048 14.0 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF3180 PF11377.8 ETZ05151.1 - 5.7 7.1 9.7 1.5 9.0 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) ABC_tran PF00005.27 ETZ05152.1 - 4.4e-33 114.7 0.0 5.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 ETZ05152.1 - 3.1e-08 33.8 0.3 1e-05 25.6 0.1 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain SMC_N PF02463.19 ETZ05152.1 - 6.6e-08 32.2 0.2 2e-07 30.7 0.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETZ05152.1 - 0.00013 21.9 1.5 0.0016 18.3 0.4 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ETZ05152.1 - 0.00016 21.6 0.1 0.00026 20.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ETZ05152.1 - 0.0002 21.8 0.1 0.00032 21.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ETZ05152.1 - 0.00032 20.4 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETZ05152.1 - 0.001 18.8 0.3 0.002 17.9 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 ETZ05152.1 - 0.0015 17.6 0.2 0.004 16.2 0.1 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 ETZ05152.1 - 0.0016 18.7 1.2 0.0096 16.2 0.2 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ETZ05152.1 - 0.002 17.5 0.2 0.0045 16.4 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 ETZ05152.1 - 0.0025 18.2 0.9 0.008 16.6 0.9 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ETZ05152.1 - 0.0033 17.9 0.0 0.004 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETZ05152.1 - 0.0047 16.9 0.1 0.0088 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ETZ05152.1 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea cobW PF02492.19 ETZ05152.1 - 0.01 15.5 0.3 0.2 11.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ETZ05152.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETZ05152.1 - 0.015 15.9 0.0 0.03 14.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 ETZ05152.1 - 0.016 14.9 0.2 0.04 13.7 0.2 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 ETZ05152.1 - 0.017 15.1 0.3 0.02 14.8 0.3 1.4 1 1 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 ETZ05152.1 - 0.018 14.7 0.2 0.19 11.4 0.1 2.0 1 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 ETZ05152.1 - 0.023 14.0 0.1 0.088 12.1 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 ETZ05152.1 - 0.024 14.4 0.1 0.075 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 ETZ05152.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 ETZ05152.1 - 0.039 14.4 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 ETZ05152.1 - 0.045 13.8 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ETZ05152.1 - 0.05 13.8 0.2 0.093 12.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ETZ05152.1 - 0.074 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Adeno_IVa2 PF02456.15 ETZ05152.1 - 0.085 11.6 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.22 ETZ05152.1 - 0.097 11.8 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 ETZ05152.1 - 0.11 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 ETZ05152.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ETZ05152.1 - 0.12 11.8 0.1 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 ETZ05152.1 - 0.12 12.1 0.4 0.24 11.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 ETZ05152.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 ETZ05152.1 - 0.2 12.0 0.8 1.2 9.5 0.4 2.0 2 0 0 2 2 2 0 AAA domain DDE_3 PF13358.6 ETZ05153.1 - 3.8e-11 43.0 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 ETZ05154.1 - 0.004 16.8 0.4 0.0043 16.7 0.4 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 ETZ05155.1 - 0.0097 15.7 0.0 0.0099 15.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Spore_III_AB PF09548.10 ETZ05156.1 - 0.008 16.3 0.2 0.008 16.3 0.2 3.5 3 1 1 4 4 4 1 Stage III sporulation protein AB (spore_III_AB) Barwin PF00967.17 ETZ05156.1 - 0.03 14.2 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 Barwin family Apolipoprotein PF01442.18 ETZ05156.1 - 0.34 10.8 3.4 16 5.3 0.2 2.7 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3258 PF11646.8 ETZ05156.1 - 4.2 7.6 9.2 3.3 7.9 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function DUF3258 Peptidase_S41 PF03572.18 ETZ05157.1 - 7.1e-42 142.8 0.1 1.3e-41 141.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 ETZ05157.1 - 4.4e-07 30.1 0.8 1.1e-06 28.9 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 ETZ05157.1 - 2.8e-06 27.1 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ETZ05157.1 - 0.0004 20.7 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ETZ05157.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain BAG PF02179.16 ETZ05157.1 - 0.063 13.7 0.0 0.56 10.7 0.0 2.2 2 0 0 2 2 2 0 BAG domain Fimbrial_PilY2 PF14481.6 ETZ05157.1 - 0.078 12.6 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 CDP-OH_P_transf PF01066.21 ETZ05158.1 - 6.1e-14 52.5 0.3 6.1e-14 52.5 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Arg_decarb_HB PF17810.1 ETZ05159.1 - 0.023 15.0 0.4 0.072 13.3 0.4 2.0 1 1 0 1 1 1 0 Arginine decarboxylase helical bundle domain Amino_oxidase PF01593.24 ETZ05159.1 - 0.075 12.3 1.8 0.099 11.9 1.8 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase I_LWEQ PF01608.17 ETZ05159.1 - 0.54 10.5 8.4 0.53 10.5 7.5 1.5 1 1 0 1 1 1 0 I/LWEQ domain LMBR1 PF04791.16 ETZ05159.1 - 1.6 7.6 11.8 1.9 7.3 11.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Med4 PF10018.9 ETZ05159.1 - 1.6 8.4 17.6 0.32 10.6 10.1 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF848 PF05852.11 ETZ05159.1 - 1.9 8.6 14.4 2.6 8.2 2.9 2.8 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_MLP1_2 PF07926.12 ETZ05159.1 - 2.1 8.4 23.8 0.053 13.6 15.0 2.7 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HSCB_C PF07743.13 ETZ05159.1 - 2.2 8.8 11.9 3.5 8.2 3.9 3.2 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2508 PF10704.9 ETZ05159.1 - 6.1 7.1 18.9 1.9 8.7 1.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) Goodbye PF17109.5 ETZ05159.1 - 7.2 7.1 14.0 13 6.2 3.0 3.2 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain GAS PF13851.6 ETZ05160.1 - 2 7.8 71.2 1.5 8.2 21.8 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding N_methyl PF07963.12 ETZ05161.1 - 0.001 18.5 0.7 0.001 18.5 0.7 1.8 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif Gram_pos_anchor PF00746.21 ETZ05161.1 - 0.18 11.8 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_holin_2_4 PF16082.5 ETZ05161.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like RmuC PF02646.16 ETZ05162.1 - 5.4e-79 265.4 0.2 5.4e-79 265.4 0.2 1.7 1 1 1 2 2 2 1 RmuC family Dak2 PF02734.17 ETZ05162.1 - 0.011 15.7 1.2 0.022 14.7 0.2 2.0 2 0 0 2 2 2 0 DAK2 domain DUF2400 PF09674.10 ETZ05162.1 - 0.024 14.6 5.6 1.4 8.9 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) IZUMO PF15005.6 ETZ05162.1 - 0.037 14.5 15.5 0.11 13.0 3.9 3.3 3 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated ANTAR PF03861.14 ETZ05162.1 - 0.071 13.0 0.7 0.23 11.3 0.7 1.8 1 0 0 1 1 1 0 ANTAR domain Plk4_PB2 PF18409.1 ETZ05162.1 - 0.21 12.3 11.4 0.81 10.4 0.1 3.8 3 1 1 4 4 4 0 Polo-like Kinase 4 Polo Box 2 ACP_PD PF04336.12 ETZ05162.1 - 0.34 11.4 8.4 0.59 10.6 3.2 2.5 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase I_LWEQ PF01608.17 ETZ05162.1 - 0.35 11.1 11.0 0.072 13.3 0.7 3.2 3 1 0 3 3 3 0 I/LWEQ domain DUF4407 PF14362.6 ETZ05162.1 - 1.6 8.0 10.9 6.1 6.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 ETZ05162.1 - 3.4 7.7 6.7 3.1 7.9 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Het-C PF07217.11 ETZ05162.1 - 5.5 5.4 9.2 0.62 8.5 0.7 2.6 2 1 1 3 3 3 0 Heterokaryon incompatibility protein Het-C Secretin PF00263.21 ETZ05163.1 - 1.7e-33 115.7 0.8 3e-33 114.9 0.8 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein DUF4974 PF16344.5 ETZ05163.1 - 4.3e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) Secretin_N_2 PF07655.13 ETZ05163.1 - 9.8e-05 22.8 0.6 0.00024 21.6 0.6 1.6 1 0 0 1 1 1 1 Secretin N-terminal domain Ala_racemase_N PF01168.20 ETZ05163.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Glyco_hydro_35 PF01301.19 ETZ05163.1 - 0.036 13.7 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 TEX13 PF15186.6 ETZ05163.1 - 0.089 12.5 0.1 0.24 11.1 0.1 1.8 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family DDE_3 PF13358.6 ETZ05164.1 - 1.2e-14 54.2 0.0 1.4e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 ETZ05165.1 - 0.064 13.1 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF3990 PF13151.6 ETZ05166.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Molybdop_Fe4S4 PF04879.16 ETZ05169.1 - 1.4e-07 31.3 0.3 7.2 6.7 0.0 5.4 1 1 4 5 5 5 3 Molybdopterin oxidoreductase Fe4S4 domain DUF2769 PF10967.8 ETZ05169.1 - 0.0086 16.7 2.1 13 6.6 0.1 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF2769) TraD PF06412.11 ETZ05169.1 - 0.028 14.2 3.2 19 5.1 0.1 3.5 3 0 0 3 3 3 0 Conjugal transfer protein TraD Toxin_24 PF08094.11 ETZ05169.1 - 0.22 11.4 4.9 1.4e+02 2.4 0.0 4.5 5 0 0 5 5 5 0 Conotoxin TVIIA/GS family ROKNT PF08067.11 ETZ05169.1 - 0.32 11.3 9.6 20 5.6 0.5 4.6 1 1 4 5 5 5 0 ROKNT (NUC014) domain Ribosomal_L32p PF01783.23 ETZ05172.1 - 3e-23 81.8 6.4 3.9e-23 81.5 6.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family FA_synthesis PF02504.15 ETZ05173.1 - 3.6e-87 292.4 0.0 4.1e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein Thioredoxin_4 PF13462.6 ETZ05174.1 - 1.7e-10 41.3 0.0 2.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ETZ05174.1 - 0.0021 18.5 2.0 0.008 16.6 0.6 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_25 PF01755.17 ETZ05176.1 - 8.1e-29 100.9 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glycos_transf_2 PF00535.26 ETZ05176.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Trans_reg_C PF00486.28 ETZ05177.1 - 9.6e-11 41.6 1.2 2.1e-10 40.5 1.2 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Phage_Mu_Gam PF07352.12 ETZ05177.1 - 0.014 15.3 1.0 1.1 9.1 0.8 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Bac_DNA_binding PF00216.21 ETZ05178.1 - 1.8e-25 89.0 0.1 2e-25 88.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ETZ05178.1 - 4e-10 39.9 0.1 5.1e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 ETZ05178.1 - 0.0012 19.0 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-DNA_bdg PF14848.6 ETZ05178.1 - 0.0014 18.6 0.1 0.0059 16.6 0.1 1.9 1 1 0 1 1 1 1 DNA-binding domain HU-CCDC81_bac_2 PF18175.1 ETZ05178.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 ETZ05178.1 - 0.016 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 MarR PF01047.22 ETZ05178.1 - 0.023 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 MarR family ABC_tran PF00005.27 ETZ05181.1 - 1.2e-28 100.3 0.0 2e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ05181.1 - 3.7e-16 59.6 5.4 6e-16 58.9 5.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ05181.1 - 1.7e-06 27.7 0.0 7.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ05181.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PsbX PF06596.11 ETZ05181.1 - 0.1 12.6 0.2 0.56 10.2 0.2 2.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) MMR_HSR1 PF01926.23 ETZ05181.1 - 0.15 12.2 0.1 0.51 10.4 0.0 1.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Peptidase_S78_2 PF14550.6 ETZ05181.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative phage serine protease XkdF rRNA_proc-arch PF13234.6 ETZ05182.1 - 0.016 15.1 0.8 0.03 14.3 0.8 1.4 1 1 0 1 1 1 0 rRNA-processing arch domain DUF4942 PF13708.6 ETZ05182.1 - 0.061 13.3 0.1 0.094 12.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4942) DnaB_C PF03796.15 ETZ05184.1 - 2.6e-101 338.3 0.2 3.3e-101 337.9 0.2 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 ETZ05184.1 - 7.1e-22 77.4 0.5 1.8e-21 76.2 0.5 1.7 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 ETZ05184.1 - 8.9e-16 58.0 0.3 1.6e-15 57.2 0.1 1.5 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.11 ETZ05184.1 - 0.00014 21.2 0.5 0.24 10.6 0.0 2.9 3 0 0 3 3 3 2 Rad51 Amido_AtzD_TrzD PF09663.10 ETZ05184.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) AAA PF00004.29 ETZ05184.1 - 0.021 15.2 0.2 0.1 13.0 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ETZ05184.1 - 0.041 13.2 0.2 0.23 10.8 0.2 2.1 1 1 0 1 1 1 0 KaiC DDE_Tnp_IS240 PF13610.6 ETZ05185.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 DDE domain ETC_C1_NDUFA5 PF04716.14 ETZ05185.1 - 0.13 12.0 0.0 1.9 8.4 0.0 2.1 1 1 1 2 2 2 0 ETC complex I subunit conserved region PS_Dcarbxylase PF02666.15 ETZ05188.1 - 3.5e-26 92.0 0.0 4.3e-25 88.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Proteasome_A_N PF10584.9 ETZ05188.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DNA_pol3_beta PF00712.19 ETZ05189.1 - 5.7e-24 84.6 0.2 3.8e-18 65.7 0.0 3.3 2 1 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 ETZ05189.1 - 3.6e-19 69.1 0.1 2.9e-17 63.0 0.0 2.5 3 0 0 3 3 3 1 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 ETZ05189.1 - 9.6e-18 64.2 0.1 5.9e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain Bac_DnaA PF00308.18 ETZ05190.1 - 2e-80 269.8 0.1 3.4e-80 269.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 ETZ05190.1 - 2.6e-28 97.8 0.0 5.8e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 ETZ05190.1 - 6.5e-13 48.2 0.3 2.9e-12 46.2 0.1 2.2 2 0 0 2 2 2 1 DnaA N-terminal domain IstB_IS21 PF01695.17 ETZ05190.1 - 1.5e-09 37.9 0.0 2.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 ETZ05190.1 - 5.8e-08 33.2 0.0 5.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 ETZ05190.1 - 8.1e-07 28.2 0.6 0.023 13.6 0.1 2.2 1 1 1 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.6 ETZ05190.1 - 9.6e-06 25.7 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ETZ05190.1 - 1.6e-05 24.9 1.7 0.00012 22.1 0.4 2.4 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ETZ05190.1 - 0.00013 22.2 0.5 0.79 10.0 0.0 3.0 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 ETZ05190.1 - 0.00019 21.8 0.1 0.0017 18.7 0.1 2.6 2 1 0 2 2 1 1 RNA helicase NACHT PF05729.12 ETZ05190.1 - 0.00045 20.2 0.0 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 ETZ05190.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ05190.1 - 0.0022 18.4 0.1 0.019 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 ETZ05190.1 - 0.024 15.0 0.1 0.73 10.2 0.0 2.9 2 2 1 3 3 3 0 AAA domain TsaE PF02367.17 ETZ05190.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Eaf7 PF07904.13 ETZ05190.1 - 0.046 14.1 1.4 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 AFP_2 PF18815.1 ETZ05190.1 - 0.061 13.6 0.4 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat AAA_25 PF13481.6 ETZ05190.1 - 0.066 12.8 0.0 0.75 9.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 ETZ05190.1 - 0.081 12.4 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 ETZ05190.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_S20p PF01649.18 ETZ05191.1 - 1.2e-15 57.9 5.9 1.3e-15 57.8 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 DDE_Tnp_IS1 PF03400.13 ETZ05192.1 - 5.1e-06 26.9 0.1 7.6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 IS1 transposase HTH_23 PF13384.6 ETZ05192.1 - 0.00095 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ05192.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 ETZ05192.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_7 PF02796.15 ETZ05192.1 - 0.059 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF2309 PF10070.9 ETZ05193.1 - 1e-205 685.4 0.0 1.9e-197 658.0 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2309) Ada3 PF10198.9 ETZ05193.1 - 0.079 13.1 0.6 0.15 12.2 0.6 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Proton_antipo_M PF00361.20 ETZ05194.1 - 4.1e-41 141.1 12.0 4.1e-41 141.1 12.0 2.3 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ETZ05194.1 - 2.8e-09 36.9 1.2 2.8e-09 36.9 1.2 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus TatD_DNase PF01026.21 ETZ05195.1 - 2e-64 217.4 0.0 2.5e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase UvrC_HhH_N PF08459.11 ETZ05196.1 - 2.5e-35 121.6 0.0 4.2e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 ETZ05196.1 - 1.2e-08 35.5 0.2 4.1e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain GIY-YIG PF01541.24 ETZ05196.1 - 2e-06 28.0 0.0 9.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 GIY-YIG catalytic domain HHH_2 PF12826.7 ETZ05196.1 - 2.3e-06 27.6 0.0 7.6e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 ETZ05196.1 - 4e-06 26.4 0.0 0.0073 16.1 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif UVR PF02151.19 ETZ05196.1 - 0.00018 21.2 0.3 0.00046 19.8 0.3 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_8 PF14716.6 ETZ05196.1 - 0.011 16.1 1.1 0.53 10.7 0.0 3.2 3 1 0 3 3 3 0 Helix-hairpin-helix domain HHH_3 PF12836.7 ETZ05196.1 - 0.012 15.9 0.2 0.29 11.4 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif LcrG PF07216.12 ETZ05196.1 - 0.11 12.4 0.6 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 LcrG protein Peptidase_S24 PF00717.23 ETZ05197.1 - 4.4e-18 65.0 0.0 9.4e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ETZ05197.1 - 0.00031 20.6 0.1 0.11 12.3 0.0 2.9 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 ABC_tran PF00005.27 ETZ05199.1 - 8.3e-35 120.3 0.0 1.4e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ05199.1 - 5.4e-20 72.2 16.6 6.8e-20 71.8 16.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ05199.1 - 0.00048 19.6 4.6 0.0052 16.2 1.6 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETZ05199.1 - 0.0019 18.1 0.7 1.4 8.6 0.0 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ETZ05199.1 - 0.0031 17.6 0.1 0.0093 16.0 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 ETZ05199.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 ETZ05199.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ETZ05199.1 - 0.038 14.4 0.4 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 ETZ05199.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 ETZ05199.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 ETZ05199.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 ETZ05199.1 - 0.13 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF4748 PF15932.5 ETZ05199.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) AAA_24 PF13479.6 ETZ05199.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETZ05199.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETZ05199.1 - 0.17 12.2 0.2 0.8 10.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain GCV_T PF01571.21 ETZ05200.1 - 0.00091 18.7 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain HTH_Tnp_IS630 PF01710.16 ETZ05201.1 - 3.7e-22 78.6 3.8 4.3e-22 78.4 3.8 1.0 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ETZ05201.1 - 1.3e-13 50.8 1.1 8.8e-08 32.2 0.3 2.4 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ETZ05201.1 - 4.6e-11 42.2 0.2 4.7e-06 26.2 0.0 2.5 3 0 0 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.6 ETZ05201.1 - 9e-05 22.4 0.2 0.0083 16.1 0.0 2.6 2 1 1 3 3 3 1 Winged helix-turn helix DUF1804 PF08822.11 ETZ05201.1 - 0.0001 22.3 1.9 0.35 10.8 0.0 2.8 1 1 1 3 3 3 2 Protein of unknown function (DUF1804) PAX PF00292.18 ETZ05201.1 - 0.00011 22.2 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_psq PF05225.16 ETZ05201.1 - 0.00021 21.0 0.3 0.00062 19.5 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Trp_repressor PF01371.19 ETZ05201.1 - 0.00046 20.3 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 2 Trp repressor protein HTH_Tnp_4 PF13613.6 ETZ05201.1 - 0.00051 19.7 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease HTH_DeoR PF08220.12 ETZ05201.1 - 0.00064 19.4 0.0 0.0078 15.9 0.0 2.2 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_17 PF12728.7 ETZ05201.1 - 0.0017 18.5 0.7 2.7 8.2 0.0 2.7 2 1 0 2 2 2 2 Helix-turn-helix domain DUF1323 PF07037.11 ETZ05201.1 - 0.0023 18.3 0.3 0.61 10.5 0.1 2.2 1 1 1 2 2 2 1 Putative transcription regulator (DUF1323) HTH_33 PF13592.6 ETZ05201.1 - 0.0024 17.5 1.5 0.0046 16.6 0.5 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 ETZ05201.1 - 0.0032 17.7 0.8 0.21 11.9 0.0 2.6 1 1 2 3 3 3 1 Transposase HTH_Tnp_ISL3 PF13542.6 ETZ05201.1 - 0.006 16.0 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 MerR_1 PF13411.6 ETZ05201.1 - 0.0074 16.4 0.2 0.094 12.8 0.1 2.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein HTH_32 PF13565.6 ETZ05201.1 - 0.01 16.5 0.9 0.18 12.4 1.2 2.7 2 1 0 2 2 2 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 ETZ05201.1 - 0.01 16.3 0.0 0.18 12.4 0.0 2.1 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 Sigma70_r4_2 PF08281.12 ETZ05201.1 - 0.017 14.8 0.0 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 ETZ05201.1 - 0.034 14.2 0.4 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix MerR PF00376.23 ETZ05201.1 - 0.04 13.7 0.2 3.3 7.6 0.0 2.5 2 1 0 2 2 2 0 MerR family regulatory protein Sigma70_r4 PF04545.16 ETZ05201.1 - 0.14 11.7 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Spore_GerAC PF05504.11 ETZ05201.1 - 0.15 12.3 3.6 0.2 11.9 1.6 1.8 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal S1 PF00575.23 ETZ05202.1 - 3.8e-83 273.9 24.3 7.1e-20 71.1 0.4 6.1 6 0 0 6 6 6 6 S1 RNA binding domain S1_2 PF13509.6 ETZ05202.1 - 2.6e-08 33.8 3.3 0.27 11.3 0.0 6.4 5 3 0 5 5 5 2 S1 domain PCB_OB PF17092.5 ETZ05202.1 - 2.7e-06 28.1 3.4 0.26 12.0 0.0 4.9 3 2 2 5 5 5 2 Penicillin-binding protein OB-like domain MRP-S35 PF10246.9 ETZ05202.1 - 0.00066 19.6 0.4 3.9 7.5 0.0 3.9 3 1 0 3 3 3 1 Mitochondrial ribosomal protein MRP-S35 DUF150_C PF17384.2 ETZ05202.1 - 0.02 15.0 1.1 13 6.0 0.1 4.0 3 1 0 3 3 3 0 RimP C-terminal SH3 domain Hexapep_2 PF14602.6 ETZ05203.1 - 4.7e-10 39.0 8.3 6.1e-08 32.3 0.3 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 ETZ05203.1 - 2.5e-08 33.3 7.9 0.0017 18.0 0.3 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) THDPS_N_2 PF14805.6 ETZ05203.1 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal LolA PF03548.15 ETZ05204.1 - 5.9e-12 45.6 0.1 7.2e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 ETZ05204.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Bac_DnaA PF00308.18 ETZ05205.1 - 4.8e-05 23.3 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial dnaA protein RuvB_N PF05496.12 ETZ05205.1 - 0.18 11.5 0.0 0.55 10.0 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain rve PF00665.26 ETZ05206.1 - 4.9e-07 30.0 0.0 6.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISL3 PF01610.17 ETZ05206.1 - 0.08 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Transposase ABC_tran PF00005.27 ETZ05207.1 - 2.5e-33 115.5 0.0 4.1e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ETZ05207.1 - 4e-15 55.7 0.1 1.1e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 ETZ05207.1 - 4e-09 36.7 0.2 0.00011 22.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ05207.1 - 3.8e-06 26.5 0.6 3.2e-05 23.5 0.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ETZ05207.1 - 0.0044 17.3 1.2 0.022 15.0 0.1 2.4 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.6 ETZ05207.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ETZ05207.1 - 0.012 15.7 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain sCache_3_2 PF17203.4 ETZ05207.1 - 0.02 15.0 0.6 0.065 13.4 0.1 2.1 2 1 0 2 2 2 0 Single cache domain 3 AAA_22 PF13401.6 ETZ05207.1 - 0.022 15.0 0.7 0.32 11.3 1.1 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ETZ05207.1 - 0.038 14.4 0.9 0.46 10.9 0.9 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KdpD PF02702.17 ETZ05207.1 - 0.042 13.3 0.1 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_16 PF13191.6 ETZ05207.1 - 0.061 13.7 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 ETZ05207.1 - 0.073 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ETZ05207.1 - 0.084 13.0 0.0 0.34 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 ETZ05207.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 ETZ05207.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 ETZ05207.1 - 0.27 11.1 0.8 0.63 9.9 0.3 1.8 2 0 0 2 2 2 0 NACHT domain DUF3510 PF12022.8 ETZ05209.1 - 2.3 8.6 12.5 7.4 7.0 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF3510) TOBE_2 PF08402.10 ETZ05210.1 - 1.5e-15 57.1 0.1 3.8e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 TOBE domain XPA_N PF01286.18 ETZ05211.1 - 0.058 13.5 0.7 5.8 7.0 0.0 2.2 2 0 0 2 2 2 0 XPA protein N-terminal DUF4347 PF14252.6 ETZ05211.1 - 0.18 11.7 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) SLT PF01464.20 ETZ05213.1 - 1.1e-11 44.4 0.0 4.9e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Transglycosylase SLT domain TPR_2 PF07719.17 ETZ05213.1 - 1.3e-06 28.1 0.3 0.071 13.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETZ05213.1 - 0.049 13.9 0.0 24 5.3 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETZ05213.1 - 0.053 13.4 0.4 26 4.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 ETZ05213.1 - 2 9.2 5.9 1.5 9.6 0.1 3.2 4 0 0 4 4 4 0 Sel1 repeat DDE_3 PF13358.6 ETZ05214.1 - 9.6e-09 35.2 0.0 1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Guanylate_kin PF00625.21 ETZ05215.1 - 7.9e-34 116.9 0.0 9.3e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase ABC_tran PF00005.27 ETZ05215.1 - 0.00041 20.9 0.0 0.00061 20.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 ETZ05215.1 - 0.0019 18.6 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETZ05215.1 - 0.0024 18.4 0.0 0.005 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ETZ05215.1 - 0.0046 16.2 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 ETZ05215.1 - 0.0059 17.0 0.1 0.0069 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 ETZ05215.1 - 0.012 15.6 0.0 0.097 12.7 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ETZ05215.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETZ05215.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETZ05215.1 - 0.023 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 ETZ05215.1 - 0.027 14.8 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ETZ05215.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 ETZ05215.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 NTPase Herpes_UL1 PF05259.11 ETZ05216.1 - 0.12 12.5 0.1 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus glycoprotein L Semialdhyde_dhC PF02774.18 ETZ05217.1 - 1.6e-34 119.6 0.0 2.1e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ETZ05217.1 - 2.2e-18 66.8 0.0 4.8e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 ETZ05217.1 - 0.067 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.20 ETZ05217.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SurA_N_3 PF13624.6 ETZ05218.1 - 6.4e-17 61.8 0.4 1.3e-16 60.8 0.4 1.6 1 0 0 1 1 1 1 SurA N-terminal domain SurA_N_2 PF13623.6 ETZ05218.1 - 3.7e-11 43.1 0.1 3.7e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 SurA N-terminal domain Rotamase_2 PF13145.6 ETZ05218.1 - 6.7e-07 30.2 10.7 0.00017 22.4 3.1 2.6 2 0 0 2 2 2 2 PPIC-type PPIASE domain 2_5_RNA_ligase2 PF13563.6 ETZ05218.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily GerE PF00196.19 ETZ05218.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family 4F5 PF04419.14 ETZ05218.1 - 2.5 9.0 5.0 6.6 7.7 5.0 1.7 1 0 0 1 1 1 0 4F5 protein family RsfS PF02410.15 ETZ05219.1 - 1.9e-22 79.5 0.4 2.3e-22 79.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Ribosomal_TL5_C PF14693.6 ETZ05221.1 - 4.7e-23 81.4 2.7 8.5e-23 80.5 2.7 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 ETZ05221.1 - 1.4e-16 60.8 0.0 1.8e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L25p family Pept_tRNA_hydro PF01195.19 ETZ05222.1 - 5.2e-46 156.7 0.0 6.1e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ATG101 PF07855.12 ETZ05223.1 - 0.5 10.3 4.7 0.92 9.5 4.6 1.7 1 1 0 1 1 1 0 Autophagy-related protein 101 DUF4379 PF14311.6 ETZ05224.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Probable Zinc-ribbon domain CEP44 PF15007.6 ETZ05225.1 - 0.036 14.2 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Peptidase_M17 PF00883.21 ETZ05227.1 - 3.1e-110 368.3 0.0 3.7e-110 368.1 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Radical_SAM PF04055.21 ETZ05228.1 - 2.2e-12 47.7 0.0 3.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 ETZ05228.1 - 1e-06 29.1 0.1 2.1e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family OMP_b-brl PF13505.6 ETZ05229.1 - 2.3e-06 27.9 1.7 1.1e-05 25.7 0.2 2.4 2 1 0 2 2 2 1 Outer membrane protein beta-barrel domain MtrB_PioB PF11854.8 ETZ05229.1 - 0.0021 16.5 0.1 0.0021 16.5 0.1 1.6 2 0 0 2 2 2 1 Putative outer membrane beta-barrel porin, MtrB/PioB OmpA_membrane PF01389.17 ETZ05229.1 - 0.0033 17.2 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 OmpA-like transmembrane domain DUF4236 PF14020.6 ETZ05229.1 - 0.064 13.8 1.4 0.19 12.3 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) DHDPS PF00701.22 ETZ05230.1 - 1e-44 152.4 0.0 1.4e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family NusB PF01029.18 ETZ05231.1 - 3.8e-16 59.6 0.0 4.8e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NusB family Trypsin_2 PF13365.6 ETZ05232.1 - 1.3e-25 91.1 0.2 1.9e-25 90.5 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ETZ05232.1 - 6.1e-20 71.3 1.6 1.5e-13 50.9 0.1 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ETZ05232.1 - 1.9e-13 50.5 1.6 8.1e-11 42.1 0.4 3.1 2 1 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 ETZ05232.1 - 3.8e-11 42.7 0.7 1e-10 41.3 0.1 2.0 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 ETZ05232.1 - 2.2e-07 30.9 0.0 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin HlyD_3 PF13437.6 ETZ05232.1 - 0.0005 20.7 0.3 0.0053 17.4 0.1 2.6 2 1 1 3 3 3 1 HlyD family secretion protein Peptidase_S29 PF02907.15 ETZ05232.1 - 0.01 15.6 0.0 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 ETZ05232.1 - 0.042 13.8 0.2 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF31 PF01732.16 ETZ05232.1 - 0.047 13.2 0.0 6.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 ETZ05232.1 - 0.38 9.4 1.2 0.6 8.7 0.3 1.6 2 0 0 2 2 2 0 Peptidase S46 adh_short_C2 PF13561.6 ETZ05233.1 - 1.7e-47 161.9 0.0 2.1e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ05233.1 - 9.6e-35 119.8 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ05233.1 - 1.1e-08 35.2 0.0 2.7e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 KR domain DUF4096 PF13340.6 ETZ05235.1 - 0.13 12.5 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) DUF2985 PF11204.8 ETZ05236.1 - 0.082 13.1 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) HTH_23 PF13384.6 ETZ05237.1 - 0.0002 21.1 0.1 0.00065 19.4 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 ETZ05237.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 ETZ05237.1 - 0.015 15.9 0.0 0.041 14.5 0.1 1.7 1 1 1 2 2 2 0 Homeodomain-like domain Prok-RING_1 PF14446.6 ETZ05238.1 - 0.12 12.3 0.3 0.28 11.1 0.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HTH_Tnp_IS630 PF01710.16 ETZ05239.1 - 5.2e-06 26.5 0.6 7.9e-06 25.9 0.6 1.3 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 ETZ05239.1 - 0.025 14.2 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 ETZ05240.1 - 0.00085 19.4 0.2 0.00097 19.2 0.2 1.1 1 0 0 1 1 1 1 Transposase UbiA PF01040.18 ETZ05241.1 - 1e-27 97.1 15.9 1.4e-27 96.6 15.9 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family TipAS PF07739.13 ETZ05242.1 - 0.59 10.7 3.0 0.58 10.7 0.4 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain MlaE PF02405.16 ETZ05243.1 - 2.9e-60 203.6 14.7 3.8e-60 203.2 14.7 1.1 1 0 0 1 1 1 1 Permease MlaE BON PF04972.17 ETZ05244.1 - 2.4e-15 56.6 0.2 6.7e-12 45.5 0.1 2.1 2 0 0 2 2 2 2 BON domain HAD PF12710.7 ETZ05245.1 - 1.7e-07 31.8 0.2 1.2e-05 25.8 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ05245.1 - 0.022 15.1 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETZ05245.1 - 0.17 11.6 0.1 5.8 6.6 0.0 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 ETZ05246.1 - 6.1e-63 213.2 0.0 7.1e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ETZ05246.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ETZ05246.1 - 0.0027 16.3 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 ETZ05246.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 ETZ05246.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V HTH_23 PF13384.6 ETZ05247.1 - 0.0002 21.1 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ05247.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 ETZ05247.1 - 0.032 14.0 0.0 0.07 12.9 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_5 PF06056.12 ETZ05247.1 - 0.04 13.8 0.2 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_psq PF05225.16 ETZ05247.1 - 0.052 13.3 0.1 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 helix-turn-helix, Psq domain GerE PF00196.19 ETZ05247.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_19 PF12844.7 ETZ05247.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 ETZ05247.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 ETZ05247.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 CSD PF00313.22 ETZ05248.1 - 1e-22 79.7 0.0 1.2e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ETZ05248.1 - 2.1e-05 24.1 0.2 2.7e-05 23.8 0.2 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain SapB_1 PF05184.15 ETZ05250.1 - 0.0012 18.8 1.0 0.0069 16.4 0.2 2.9 2 0 0 2 2 2 1 Saposin-like type B, region 1 Prefoldin_3 PF13758.6 ETZ05250.1 - 0.081 13.0 3.8 0.57 10.3 0.0 3.1 3 0 0 3 3 3 0 Prefoldin subunit Aida_N PF08910.10 ETZ05250.1 - 0.23 11.9 5.8 0.19 12.1 1.1 3.0 3 0 0 3 3 3 0 Aida N-terminus DUF4259 PF14078.6 ETZ05250.1 - 0.44 11.3 2.0 15 6.3 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4259) UPF0449 PF15136.6 ETZ05250.1 - 1.2 9.6 7.2 2.6 8.6 0.1 3.7 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 FTSW_RODA_SPOVE PF01098.19 ETZ05253.1 - 2.2e-72 244.1 23.7 2.5e-72 243.9 23.7 1.0 1 0 0 1 1 1 1 Cell cycle protein Otopetrin PF03189.13 ETZ05253.1 - 0.045 12.6 0.3 0.079 11.8 0.3 1.3 1 0 0 1 1 1 0 Otopetrin DUF4262 PF14081.6 ETZ05253.1 - 0.05 13.8 0.0 0.083 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) TMEM192 PF14802.6 ETZ05253.1 - 0.085 11.9 2.1 0.22 10.6 2.1 1.6 1 0 0 1 1 1 0 TMEM192 family YtpI PF14007.6 ETZ05253.1 - 1 9.5 6.9 9.9 6.4 1.7 2.7 2 0 0 2 2 2 0 YtpI-like protein Mur_ligase_M PF08245.12 ETZ05254.1 - 2.1e-18 67.0 0.0 3.1e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain PGK PF00162.19 ETZ05254.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase BPD_transp_1 PF00528.22 ETZ05256.1 - 5.6e-16 58.8 15.3 5.6e-16 58.8 15.3 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component tRNA-synt_1b PF00579.25 ETZ05257.1 - 4.5e-54 183.7 0.0 6e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 ETZ05257.1 - 0.03 13.2 0.1 11 4.9 0.0 2.9 2 1 0 3 3 3 0 tRNA synthetases class I (K) THP2 PF09432.10 ETZ05257.1 - 0.078 13.0 0.4 0.42 10.7 0.0 2.3 3 0 0 3 3 3 0 Tho complex subunit THP2 Peptidase_S49 PF01343.18 ETZ05259.1 - 7.7e-52 175.3 0.4 1e-36 126.2 0.1 2.2 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 ETZ05259.1 - 4.1e-07 30.0 0.2 0.00062 19.7 0.0 3.2 3 0 0 3 3 3 2 Clp protease adh_short_C2 PF13561.6 ETZ05260.1 - 2.5e-83 279.2 0.1 2.8e-83 279.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ05260.1 - 1e-27 96.9 0.0 1.4e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ05260.1 - 0.0085 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain UPF0054 PF02130.17 ETZ05262.1 - 6.4e-25 87.4 0.0 8.3e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Bromo_TP PF07524.13 ETZ05262.1 - 0.16 12.0 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated CorC_HlyC PF03471.17 ETZ05263.1 - 5e-14 52.1 0.0 1.7e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 ETZ05263.1 - 6.3e-11 42.6 0.0 3.4e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain DDE_3 PF13358.6 ETZ05264.1 - 1.8e-11 44.0 0.1 2e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease VanW PF04294.13 ETZ05265.1 - 1.3e-36 125.1 0.0 2e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 VanW like protein LRR_4 PF12799.7 ETZ05266.1 - 2e-08 34.4 2.3 1.6e-06 28.3 0.1 4.1 1 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETZ05266.1 - 3.5e-06 26.7 1.2 0.092 12.5 0.3 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 ETZ05266.1 - 2.6e-05 23.9 0.0 0.33 11.1 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat LRR_9 PF14580.6 ETZ05266.1 - 0.0033 16.9 0.4 0.013 15.0 0.4 1.9 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ETZ05267.1 - 1.4e-08 34.9 4.4 8.1e-07 29.3 0.7 4.0 2 2 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ETZ05267.1 - 4.1e-05 23.3 0.0 0.68 10.1 0.0 2.9 2 0 0 2 2 2 2 Leucine Rich repeat LRR_8 PF13855.6 ETZ05267.1 - 6.6e-05 22.6 0.4 0.35 10.7 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 ETZ05267.1 - 0.0099 15.4 0.4 0.023 14.2 0.4 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 ETZ05267.1 - 0.048 14.2 1.6 13 6.8 0.4 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat EPSP_synthase PF00275.20 ETZ05268.1 - 2.9e-80 270.0 0.0 3.2e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Ycf4 PF02392.16 ETZ05271.1 - 0.26 10.8 2.0 0.72 9.4 2.0 1.8 1 0 0 1 1 1 0 Ycf4 DUF3377 PF11857.8 ETZ05271.1 - 0.73 9.8 2.0 1.1 9.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SID-1_RNA_chan PF13965.6 ETZ05273.1 - 0.15 10.5 3.1 0.19 10.1 3.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 ETZ05273.1 - 0.17 10.8 7.9 0.2 10.5 7.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 ETZ05273.1 - 0.32 10.2 7.7 0.36 10.0 7.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 ETZ05273.1 - 0.34 8.8 4.7 0.38 8.6 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 ETZ05273.1 - 0.64 9.8 16.9 0.83 9.4 16.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Smg8_Smg9 PF10220.9 ETZ05273.1 - 1.3 7.2 12.1 1.5 7.1 12.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF3827 PF12877.7 ETZ05273.1 - 1.4 7.2 16.8 1.7 6.9 16.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) O-antigen_lig PF13425.6 ETZ05273.1 - 1.9 7.2 3.2 2 7.1 3.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SDA1 PF05285.12 ETZ05273.1 - 2 7.8 30.4 2.4 7.5 30.4 1.0 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 ETZ05273.1 - 3 7.9 7.3 3.5 7.6 7.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 ETZ05273.1 - 3.5 6.9 6.9 4.1 6.7 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Raftlin PF15250.6 ETZ05273.1 - 5.6 5.6 14.5 6.7 5.4 14.5 1.0 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 ETZ05273.1 - 5.8 5.6 15.3 6.8 5.3 15.3 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 ETZ05273.1 - 5.9 5.8 13.5 6.9 5.6 13.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 ETZ05273.1 - 5.9 5.5 13.8 6.6 5.4 13.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein rve PF00665.26 ETZ05274.1 - 1.8e-09 37.8 0.0 2.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISL3 PF01610.17 ETZ05274.1 - 0.0002 21.2 0.1 0.00067 19.4 0.1 1.5 1 1 0 2 2 2 1 Transposase rve_3 PF13683.6 ETZ05274.1 - 0.027 14.3 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain Aminotran_1_2 PF00155.21 ETZ05275.1 - 1.8e-50 172.1 0.0 2.1e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ETZ05275.1 - 6.1e-05 21.7 0.0 9.3e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3352 PF11832.8 ETZ05275.1 - 0.2 10.3 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) BATS PF06968.13 ETZ05276.1 - 3.3e-21 75.2 0.0 1.7e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ETZ05276.1 - 1.3e-15 58.2 0.3 4.6e-15 56.4 0.4 1.8 2 0 0 2 2 2 1 Radical SAM superfamily DUF3795 PF12675.7 ETZ05276.1 - 0.093 13.2 1.5 0.17 12.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) Phasin_2 PF09361.10 ETZ05276.1 - 0.095 13.0 0.1 9.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Phasin protein SecA_DEAD PF07517.14 ETZ05277.1 - 5.3e-129 429.6 2.3 5.3e-129 429.6 2.3 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain SecA_SW PF07516.13 ETZ05277.1 - 3e-50 171.0 9.3 3e-50 171.0 9.3 3.2 4 0 0 4 4 4 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 ETZ05277.1 - 6.1e-34 117.0 2.0 2.2e-33 115.2 2.0 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 ETZ05277.1 - 1.3e-07 31.4 8.5 2.3e-07 30.6 8.5 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 ETZ05277.1 - 1.1e-05 25.3 0.1 6.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETZ05277.1 - 0.012 16.0 1.2 0.046 14.1 0.0 2.7 2 0 0 2 2 2 0 Helicase conserved C-terminal domain RPW8 PF05659.11 ETZ05277.1 - 0.02 14.6 9.6 0.19 11.4 0.4 3.7 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 YbaB_DNA_bd PF02575.16 ETZ05277.1 - 1.2 9.4 4.8 28 5.0 0.3 3.2 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family HIT PF01230.23 ETZ05278.1 - 6.3e-17 62.1 0.0 7.2e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ETZ05278.1 - 1.4e-09 38.4 0.0 1.8e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SH3_2 PF07653.17 ETZ05278.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Foamy_BEL PF03274.14 ETZ05278.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein DUF3576 PF12100.8 ETZ05279.1 - 1.4e-18 66.8 0.0 2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3576) NOG1 PF06858.14 ETZ05279.1 - 0.06 13.1 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) tRNA-synt_1 PF00133.22 ETZ05280.1 - 1.5e-63 215.1 2.2 1.9e-22 79.3 0.5 5.9 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 ETZ05280.1 - 3.5e-52 176.6 0.0 5.8e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ETZ05280.1 - 1.8e-30 106.0 0.4 2e-16 59.8 0.0 4.5 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETZ05280.1 - 4.8e-13 49.3 0.1 1e-12 48.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ETZ05280.1 - 1.6e-08 34.3 0.0 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ETZ05280.1 - 3.6e-07 29.4 0.0 0.0037 16.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 ETZ05280.1 - 0.0095 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DNA_ligase_ZBD PF03119.16 ETZ05280.1 - 0.46 10.6 3.0 22 5.2 0.0 2.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain ABC_tran PF00005.27 ETZ05281.1 - 2e-45 154.7 1.8 1.1e-21 77.8 0.0 3.3 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 ETZ05281.1 - 4.2e-16 59.6 6.2 0.001 18.9 0.0 4.6 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ05281.1 - 1.1e-13 51.2 1.4 0.0031 17.0 0.0 4.4 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETZ05281.1 - 5.9e-10 39.5 2.9 0.00022 21.5 0.0 3.2 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 ETZ05281.1 - 5.7e-09 36.1 2.0 0.0038 17.2 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 ETZ05281.1 - 1.6e-08 35.1 0.3 0.0033 17.8 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain Rad17 PF03215.15 ETZ05281.1 - 4.9e-08 33.1 0.2 0.0019 18.2 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain MMR_HSR1 PF01926.23 ETZ05281.1 - 5.2e-08 33.0 0.0 0.0068 16.5 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ETZ05281.1 - 1.4e-07 31.2 0.1 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 ETZ05281.1 - 3e-07 30.8 0.0 0.028 14.8 0.0 2.9 3 0 0 3 3 2 2 RNA helicase RsgA_GTPase PF03193.16 ETZ05281.1 - 5e-07 29.8 0.2 0.036 14.0 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA PF00004.29 ETZ05281.1 - 1.4e-06 28.8 0.0 0.077 13.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ETZ05281.1 - 2.1e-06 28.4 11.2 0.0085 16.6 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 ETZ05281.1 - 4.2e-06 27.3 0.2 0.14 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 ETZ05281.1 - 5e-06 26.7 0.0 0.16 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ETZ05281.1 - 1.2e-05 25.7 0.2 0.26 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ETZ05281.1 - 1.6e-05 24.8 8.4 0.015 15.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 ETZ05281.1 - 2.9e-05 24.1 0.4 0.52 10.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.17 ETZ05281.1 - 4.3e-05 23.7 1.4 1 9.4 0.1 3.6 3 0 0 3 3 3 2 Helicase HerA, central domain NB-ARC PF00931.22 ETZ05281.1 - 4.7e-05 22.7 0.0 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ATP-synt_ab PF00006.25 ETZ05281.1 - 6.2e-05 22.8 0.0 0.08 12.6 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 ETZ05281.1 - 0.00031 20.7 1.6 0.46 10.3 0.0 2.7 3 0 0 3 3 2 2 ATPase domain predominantly from Archaea TsaE PF02367.17 ETZ05281.1 - 0.00034 20.6 0.7 0.08 12.9 0.0 2.7 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 ETZ05281.1 - 0.00036 19.6 0.1 0.097 11.6 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 ETZ05281.1 - 0.00044 19.5 0.4 0.45 9.6 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 ETZ05281.1 - 0.00063 19.7 0.1 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ETZ05281.1 - 0.00071 19.2 0.1 0.3 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ETZ05281.1 - 0.00082 19.2 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 ETZ05281.1 - 0.00086 19.1 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 ETZ05281.1 - 0.0013 18.5 0.2 0.77 9.5 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 ETZ05281.1 - 0.0013 18.1 0.1 0.78 9.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 ETZ05281.1 - 0.0013 18.3 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 ETZ05281.1 - 0.0015 18.3 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ETZ05281.1 - 0.0021 18.3 0.2 3.2 8.0 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 ETZ05281.1 - 0.0042 17.0 1.3 3.3 7.6 0.0 3.4 4 0 0 4 4 2 1 NTPase PRK PF00485.18 ETZ05281.1 - 0.0048 16.7 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.12 ETZ05281.1 - 0.0056 16.4 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Dynamin_N PF00350.23 ETZ05281.1 - 0.0064 16.6 0.3 1.5 8.9 0.0 2.9 3 0 0 3 3 2 1 Dynamin family dNK PF01712.19 ETZ05281.1 - 0.0065 16.3 0.2 3 7.6 0.0 2.6 2 0 0 2 2 2 1 Deoxynucleoside kinase Cytidylate_kin PF02224.18 ETZ05281.1 - 0.0091 15.8 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 ETZ05281.1 - 0.0099 15.1 0.0 0.87 8.8 0.0 2.5 2 1 0 2 2 2 1 KAP family P-loop domain ABC_tran_Xtn PF12848.7 ETZ05281.1 - 0.021 14.9 1.7 8.1 6.5 0.3 2.8 2 0 0 2 2 2 0 ABC transporter Adeno_IVa2 PF02456.15 ETZ05281.1 - 0.021 13.7 0.3 0.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein MobB PF03205.14 ETZ05281.1 - 0.028 14.3 0.2 8 6.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 ETZ05281.1 - 0.035 14.5 0.0 7.3 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ETZ05281.1 - 0.039 13.7 0.4 5.8 6.6 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 ETZ05281.1 - 0.043 13.7 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 ETZ05281.1 - 0.044 13.3 0.1 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 ETZ05281.1 - 0.051 12.8 0.0 7 5.8 0.0 2.3 2 0 0 2 2 2 0 Septin Ras PF00071.22 ETZ05281.1 - 0.063 12.9 0.0 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Ras family Mg_chelatase PF01078.21 ETZ05281.1 - 0.11 11.8 0.0 9.4 5.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran_CTD PF16326.5 ETZ05281.1 - 0.14 12.5 7.2 0.58 10.4 7.2 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain HipN PF18253.1 ETZ05281.1 - 0.15 11.8 0.1 1.6 8.5 0.0 2.9 3 0 0 3 3 2 0 Hsp70-interacting protein N N-terminal domain G-alpha PF00503.20 ETZ05281.1 - 0.36 9.9 4.3 2.6 7.1 0.0 3.0 3 1 0 3 3 3 0 G-protein alpha subunit CelTOS PF18659.1 ETZ05285.1 - 0.091 13.2 4.5 0.99 9.9 0.0 2.8 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites PDDEXK_1 PF12705.7 ETZ05286.1 - 3.2e-15 56.7 0.0 8e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily SfsA PF03749.13 ETZ05287.1 - 6.7e-41 139.4 0.0 1.1e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 ETZ05287.1 - 4.8e-14 52.2 0.0 1.6e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 SfsA N-terminal OB domain ZnuA PF01297.17 ETZ05288.1 - 7.9e-29 100.8 0.0 9.8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic ABC-3 PF00950.17 ETZ05288.1 - 1.6e-25 90.1 12.9 2e-25 89.8 12.9 1.1 1 0 0 1 1 1 1 ABC 3 transport family tRNA-synt_1c PF00749.21 ETZ05289.1 - 1.9e-79 266.8 0.0 2.8e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain RecA PF00154.21 ETZ05290.1 - 1.8e-135 450.5 1.5 2.1e-135 450.3 1.5 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 ETZ05290.1 - 2.1e-13 50.1 0.7 9.6e-13 48.0 0.7 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 ETZ05290.1 - 3.1e-09 36.5 2.7 3.7e-06 26.4 1.8 3.6 2 1 0 2 2 2 1 KaiC ATPase_2 PF01637.18 ETZ05290.1 - 8.3e-07 29.2 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ETZ05290.1 - 1.6e-05 24.7 0.0 4.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ05290.1 - 0.00036 21.0 0.0 0.00075 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETZ05290.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_35 PF14516.6 ETZ05290.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.6 ETZ05290.1 - 0.037 14.1 0.0 0.16 12.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 ETZ05290.1 - 0.043 14.2 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ETZ05290.1 - 0.067 12.8 0.1 0.82 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain CobU PF02283.16 ETZ05290.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PAXNEB PF05625.11 ETZ05290.1 - 0.098 11.8 0.4 0.16 11.1 0.4 1.3 1 0 0 1 1 1 0 PAXNEB protein AAA_22 PF13401.6 ETZ05290.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PRP3 PF08572.10 ETZ05291.1 - 0.032 14.0 2.0 0.033 13.9 2.0 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) ARTD15_N PF18084.1 ETZ05293.1 - 0.003 17.8 0.5 2.3 8.5 0.0 3.1 3 1 1 4 4 4 2 ARTD15 N-terminal domain Sigma70_r4_2 PF08281.12 ETZ05294.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 ETZ05294.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain P4Ha_N PF08336.11 ETZ05295.1 - 0.1 12.6 2.2 0.11 12.5 0.1 2.2 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3347 PF11827.8 ETZ05295.1 - 0.25 11.5 8.9 1.2 9.3 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Redoxin PF08534.10 ETZ05297.1 - 9.3e-07 28.7 0.0 4e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 ETZ05297.1 - 2.2e-06 27.6 0.0 0.00017 21.6 0.0 2.3 1 1 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 ETZ05297.1 - 3.1e-06 27.1 0.0 8.1e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ETZ05297.1 - 4e-06 27.1 0.0 2.1e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ETZ05297.1 - 0.0023 17.7 0.0 0.0063 16.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin TraF PF13728.6 ETZ05297.1 - 0.0037 17.1 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 ETZ05297.1 - 0.0069 16.8 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain dCMP_cyt_deam_1 PF00383.23 ETZ05298.1 - 1.5e-07 31.2 0.9 1.9e-07 30.9 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ETZ05298.1 - 0.00076 19.1 0.7 0.0025 17.5 0.1 1.8 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.12 ETZ05298.1 - 0.0034 17.6 0.0 0.0043 17.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Ribosomal_L28 PF00830.19 ETZ05298.1 - 0.1 12.8 0.2 0.2 11.9 0.0 1.5 2 0 0 2 2 2 0 Ribosomal L28 family DUF678 PF05077.12 ETZ05298.1 - 0.12 12.5 2.9 0.37 11.0 2.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF678) DUF948 PF06103.11 ETZ05300.1 - 0.15 12.4 1.9 5.4 7.3 0.0 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DDE_Tnp_1 PF01609.21 ETZ05301.1 - 0.0018 18.0 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DUF1283 PF06932.11 ETZ05301.1 - 0.1 12.8 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Transket_pyr PF02779.24 ETZ05302.1 - 1.2e-46 158.7 0.0 1.6e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETZ05302.1 - 9.4e-36 122.4 0.0 1.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ETZ05302.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 ETZ05303.1 - 9.5e-79 264.1 0.2 1.2e-78 263.7 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ETZ05303.1 - 7.5e-15 54.5 0.0 2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ETZ05303.1 - 1.2e-13 51.2 0.0 2.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain tRNA_synthFbeta PF17759.1 ETZ05304.1 - 1.7e-33 115.9 0.0 2.4e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 ETZ05304.1 - 1e-23 83.9 0.0 1.7e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_bind PF01588.20 ETZ05304.1 - 4.7e-15 55.5 0.1 1.2e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain B5 PF03484.15 ETZ05304.1 - 7.8e-11 42.1 0.0 2.3e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetase B5 domain FDX-ACB PF03147.14 ETZ05304.1 - 0.00029 21.2 0.0 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain RB_A PF01858.17 ETZ05305.1 - 0.016 15.1 2.9 0.016 15.1 2.9 1.9 1 1 1 2 2 2 0 Retinoblastoma-associated protein A domain 7TMR-HDED PF07697.11 ETZ05305.1 - 0.047 13.8 6.5 0.077 13.1 6.5 1.3 1 0 0 1 1 1 0 7TM-HD extracellular DUF4806 PF16064.5 ETZ05305.1 - 0.16 12.3 5.6 6.1 7.2 1.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) DUF4407 PF14362.6 ETZ05305.1 - 0.32 10.3 10.1 0.048 13.0 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TetR_C_8 PF14278.6 ETZ05305.1 - 0.37 10.9 6.7 0.099 12.8 1.3 2.6 2 2 1 3 3 3 0 Transcriptional regulator C-terminal region DDE_3 PF13358.6 ETZ05306.1 - 9.3e-07 28.7 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TIG_plexin PF17960.1 ETZ05306.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 TIG domain DDE_Tnp_1_2 PF13586.6 ETZ05308.1 - 1.6e-06 28.3 0.1 1.7e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain AntA PF08346.12 ETZ05308.1 - 0.0058 17.2 0.2 0.0073 16.8 0.2 1.4 1 1 0 1 1 1 1 AntA/AntB antirepressor DDE_Tnp_1 PF01609.21 ETZ05308.1 - 0.076 12.6 0.2 0.076 12.6 0.2 1.1 1 0 0 1 1 1 0 Transposase DDE domain DUF4096 PF13340.6 ETZ05309.1 - 3.3e-13 49.7 1.8 3.4e-13 49.6 0.2 1.7 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) DUF1539 PF07560.11 ETZ05309.1 - 0.016 15.3 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) RuvB_N PF05496.12 ETZ05311.1 - 3.8e-72 241.2 0.0 5.3e-72 240.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RuvB_C PF05491.13 ETZ05311.1 - 5e-25 87.2 0.1 1.3e-24 85.8 0.1 1.8 2 0 0 2 2 1 1 RuvB C-terminal winged helix domain AAA_lid_4 PF17864.1 ETZ05311.1 - 2.1e-18 65.9 0.0 3.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 RuvB AAA lid domain AAA PF00004.29 ETZ05311.1 - 5e-18 65.8 0.0 9.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETZ05311.1 - 2e-10 40.8 0.1 3.7e-08 33.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ETZ05311.1 - 4e-07 29.9 0.0 0.015 15.0 0.0 2.5 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 ETZ05311.1 - 1.6e-06 28.6 0.5 0.00022 21.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 ETZ05311.1 - 1.7e-06 27.5 0.0 9.3e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 ETZ05311.1 - 1.1e-05 25.3 0.1 0.00087 19.2 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETZ05311.1 - 1.5e-05 25.3 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 ETZ05311.1 - 2.5e-05 24.6 0.8 0.032 14.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 ETZ05311.1 - 6.7e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.15 ETZ05311.1 - 7.6e-05 22.8 0.1 0.045 13.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 ETZ05311.1 - 0.00013 22.0 0.0 0.00034 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ETZ05311.1 - 0.00037 20.4 0.1 0.014 15.4 0.0 2.4 1 1 0 2 2 2 1 NTPase DUF815 PF05673.13 ETZ05311.1 - 0.00038 19.7 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ETZ05311.1 - 0.00084 18.8 3.1 0.16 11.3 0.4 3.0 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 ETZ05311.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Rad17 PF03215.15 ETZ05311.1 - 0.0028 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 ETZ05311.1 - 0.0029 17.9 0.8 0.43 10.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 ETZ05311.1 - 0.0042 17.1 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 ETZ05311.1 - 0.0042 16.9 0.4 0.054 13.3 0.2 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.17 ETZ05311.1 - 0.0051 16.6 0.2 0.03 14.1 0.2 2.0 1 1 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 ETZ05311.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 ETZ05311.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ETZ05311.1 - 0.019 14.4 0.1 0.29 10.5 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 ETZ05311.1 - 0.019 14.7 0.2 0.3 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 ETZ05311.1 - 0.02 14.0 0.1 0.61 9.1 0.1 2.1 1 1 0 1 1 1 0 MCM P-loop domain AAA_PrkA PF08298.11 ETZ05311.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain AAA_18 PF13238.6 ETZ05311.1 - 0.036 14.6 0.0 0.062 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ETZ05311.1 - 0.037 13.8 0.1 0.097 12.4 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 ETZ05311.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.11 ETZ05311.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 ETZ05311.1 - 0.22 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETZ05311.1 - 0.23 10.7 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AI-2E_transport PF01594.16 ETZ05312.1 - 9.8e-42 143.3 35.8 1.1e-41 143.0 35.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter CDP-OH_P_transf PF01066.21 ETZ05313.1 - 1.4e-11 45.0 0.8 1.4e-11 45.0 0.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DDE_Tnp_IS240 PF13610.6 ETZ05315.1 - 0.041 14.1 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 DDE domain RadC PF04002.15 ETZ05318.1 - 1.1e-36 125.5 0.0 1.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 ETZ05318.1 - 0.00084 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Toxin-JAB1 PF15659.6 ETZ05318.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 JAB-like toxin 1 PP-binding PF00550.25 ETZ05320.1 - 1e-09 38.6 0.2 1.3e-09 38.3 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ETZ05320.1 - 5.9e-05 23.2 0.3 0.00013 22.1 0.1 1.5 1 1 1 2 2 2 1 Acyl-carrier DUF1493 PF07377.12 ETZ05320.1 - 0.042 14.3 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF4956 PF16316.5 ETZ05320.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4956) ketoacyl-synt PF00109.26 ETZ05321.1 - 2.2e-55 188.0 0.0 3.7e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETZ05321.1 - 1.9e-33 115.0 0.1 3e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ETZ05321.1 - 0.024 14.0 0.3 0.037 13.4 0.3 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ETZ05321.1 - 0.052 14.0 0.1 0.17 12.4 0.1 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension IKBKB_SDD PF18397.1 ETZ05322.1 - 0.063 12.6 0.0 0.073 12.4 0.0 1.0 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain ETC_C1_NDUFA5 PF04716.14 ETZ05322.1 - 0.12 12.1 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 ETC complex I subunit conserved region Ribosomal_L27 PF01016.19 ETZ05324.1 - 4.6e-34 116.3 1.8 5.1e-34 116.1 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 ETZ05325.1 - 1.4e-22 79.8 2.3 2.9e-22 78.8 2.3 1.5 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein LGT PF01790.18 ETZ05326.1 - 9.1e-66 221.5 10.3 1e-65 221.4 10.3 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase ATP-synt_ab PF00006.25 ETZ05327.1 - 1e-24 87.4 0.1 1.4e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_RNA_bind PF07497.12 ETZ05327.1 - 5.9e-21 74.1 0.0 1.1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain Rho_N PF07498.12 ETZ05327.1 - 0.0034 17.3 0.1 0.0088 16.0 0.1 1.8 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NACHT PF05729.12 ETZ05327.1 - 0.0063 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 ETZ05327.1 - 0.007 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ05327.1 - 0.0074 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ETZ05327.1 - 0.012 15.2 0.1 0.064 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETZ05327.1 - 0.021 15.2 0.0 0.16 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 ETZ05327.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Terminase_GpA PF05876.12 ETZ05327.1 - 0.2 10.2 0.0 3.4 6.1 0.0 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) NusB PF01029.18 ETZ05330.1 - 0.022 15.0 2.9 0.036 14.3 2.0 1.9 1 1 0 1 1 1 0 NusB family Frankia_peptide PF14407.6 ETZ05330.1 - 0.065 13.2 0.1 0.92 9.5 0.2 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Fib_alpha PF08702.10 ETZ05330.1 - 0.13 12.4 16.8 0.032 14.4 10.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 ETZ05331.1 - 1.5e-64 216.6 0.0 1.1e-34 119.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETZ05331.1 - 8.3e-17 61.4 2.7 1.3e-08 34.6 0.3 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETZ05331.1 - 1e-12 48.5 12.3 3.8e-05 23.6 0.4 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETZ05331.1 - 3.9e-11 43.4 2.5 8.2e-05 22.9 0.2 3.7 2 2 0 2 2 2 2 AAA domain oligo_HPY PF08352.12 ETZ05331.1 - 5.9e-10 39.5 0.0 1.8e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 ETZ05331.1 - 5.3e-09 35.7 0.6 0.00021 21.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ETZ05331.1 - 2.8e-08 34.3 0.2 0.00032 21.1 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 ETZ05331.1 - 5e-07 29.6 0.8 0.025 14.3 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ETZ05331.1 - 1.3e-06 28.4 0.1 0.0096 15.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 ETZ05331.1 - 2.1e-06 27.8 0.0 0.021 14.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 ETZ05331.1 - 6.2e-06 25.9 0.0 0.094 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 ETZ05331.1 - 9.6e-06 26.0 0.0 0.019 15.4 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETZ05331.1 - 1e-05 25.5 0.2 0.027 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETZ05331.1 - 5.4e-05 22.5 0.0 0.0081 15.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ETZ05331.1 - 9.7e-05 21.8 0.6 0.18 11.2 0.1 3.0 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ETZ05331.1 - 0.00014 21.3 0.0 0.45 9.8 0.1 2.3 2 0 0 2 2 2 2 KaiC DUF2075 PF09848.9 ETZ05331.1 - 0.0002 20.7 0.0 0.52 9.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 ETZ05331.1 - 0.00028 20.6 3.6 0.19 11.5 0.0 3.1 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_23 PF13476.6 ETZ05331.1 - 0.00037 21.1 0.0 0.021 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ETZ05331.1 - 0.00064 19.3 0.1 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 ETZ05331.1 - 0.0007 19.4 0.5 0.92 9.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 ETZ05331.1 - 0.0011 19.5 0.0 0.017 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 ETZ05331.1 - 0.0016 18.4 0.2 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase PhoH PF02562.16 ETZ05331.1 - 0.0023 17.4 0.1 0.64 9.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 ETZ05331.1 - 0.0038 17.4 0.1 0.28 11.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ETZ05331.1 - 0.0043 16.3 0.1 0.4 9.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 ETZ05331.1 - 0.0045 17.1 0.0 1.3 9.1 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 ETZ05331.1 - 0.0078 15.3 0.1 3.2 6.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 ETZ05331.1 - 0.015 15.7 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.23 ETZ05331.1 - 0.016 15.3 0.6 0.28 11.2 0.0 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 ETZ05331.1 - 0.018 14.8 0.0 3.4 7.4 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase Hpr_kinase_C PF07475.12 ETZ05331.1 - 0.019 14.5 2.2 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SbcCD_C PF13558.6 ETZ05331.1 - 0.019 15.2 0.2 11 6.4 0.0 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 ETZ05331.1 - 0.02 14.7 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 ETZ05331.1 - 0.025 14.6 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ETZ05331.1 - 0.028 13.7 0.3 0.67 9.2 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 ETZ05331.1 - 0.028 14.1 0.0 0.44 10.2 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 ETZ05331.1 - 0.03 14.4 3.7 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_ATPase PF09818.9 ETZ05331.1 - 0.031 13.1 0.2 7.4 5.2 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Pox_A32 PF04665.12 ETZ05331.1 - 0.033 13.7 1.2 4.6 6.6 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_30 PF13604.6 ETZ05331.1 - 0.038 13.7 0.3 2 8.1 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.6 ETZ05331.1 - 0.055 13.2 0.8 1.2 8.8 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain MeaB PF03308.16 ETZ05331.1 - 0.057 12.4 0.1 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ETZ05331.1 - 0.079 13.2 0.3 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ETZ05331.1 - 0.089 12.1 0.0 4.3 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 ETZ05331.1 - 0.21 11.5 0.9 1.2 9.0 0.0 2.5 3 0 0 3 3 2 0 NTPase KKLCAg1 PF15204.6 ETZ05331.1 - 0.38 10.9 2.1 2.5 8.2 0.0 3.1 3 0 0 3 3 2 0 Kita-kyushu lung cancer antigen 1 BPD_transp_1 PF00528.22 ETZ05332.1 - 2.6e-23 82.7 7.1 4.4e-23 82.0 7.1 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ETZ05332.1 - 0.032 14.2 0.2 0.032 14.2 0.2 3.2 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 ETZ05333.1 - 1.8e-32 112.6 15.2 1.8e-32 112.6 15.2 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ycf70 PF17382.2 ETZ05333.1 - 0.12 12.8 3.7 0.68 10.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Herpes_glycop PF01528.16 ETZ05333.1 - 0.82 8.5 12.9 3.2 6.5 5.1 2.3 1 1 1 2 2 2 0 Herpesvirus glycoprotein M HlyD_D23 PF16576.5 ETZ05334.1 - 1.5e-13 50.4 0.0 2.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 ETZ05334.1 - 1.1e-06 28.3 0.0 2.3e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 ETZ05334.1 - 0.00021 22.0 0.0 0.013 16.2 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein PASTA PF03793.19 ETZ05334.1 - 0.025 14.4 0.0 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 PASTA domain Biotin_lipoyl PF00364.22 ETZ05334.1 - 0.067 13.0 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme Rsbr_N PF08678.10 ETZ05335.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Rsbr N terminal FAD_binding_7 PF03441.14 ETZ05336.1 - 4.8e-81 271.1 1.5 9.2e-81 270.2 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ETZ05336.1 - 3.1e-32 111.9 0.0 6.9e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase Syntaxin_2 PF14523.6 ETZ05338.1 - 0.24 11.8 6.9 0.16 12.4 1.7 2.3 1 1 1 2 2 2 0 Syntaxin-like protein DUF724 PF05266.14 ETZ05338.1 - 0.28 11.0 6.1 0.45 10.3 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sec20 PF03908.13 ETZ05338.1 - 0.85 9.6 3.4 1.7 8.6 2.3 2.1 2 1 0 2 2 2 0 Sec20 DUF2524 PF10732.9 ETZ05338.1 - 1.3 9.4 5.4 1.1 9.5 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) TMPIT PF07851.13 ETZ05338.1 - 1.3 8.1 5.3 1.9 7.7 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF948 PF06103.11 ETZ05338.1 - 2.3 8.5 4.4 27 5.1 4.3 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5446 PF17522.2 ETZ05338.1 - 2.5 8.3 7.2 1.9 8.7 2.2 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5446) FlaC_arch PF05377.11 ETZ05338.1 - 4.8 7.6 10.5 5.1 7.6 3.1 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Antimicrobial21 PF14861.6 ETZ05339.1 - 1.7 8.4 5.8 0.24 11.1 0.7 2.2 2 1 0 2 2 2 0 Plant antimicrobial peptide SpoU_methylase PF00588.19 ETZ05340.1 - 8e-24 84.4 0.0 1.5e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ETZ05340.1 - 2.1e-05 24.7 0.0 0.027 14.7 0.0 2.4 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding RNase_H PF00075.24 ETZ05341.1 - 1.3e-39 135.7 0.1 2e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 RNase H SH3_4 PF06347.13 ETZ05341.1 - 3.2e-18 65.3 7.4 2.8e-10 39.9 1.5 2.9 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_3 PF08239.11 ETZ05341.1 - 2.5e-06 27.7 6.2 0.027 14.7 1.2 3.3 3 0 0 3 3 3 2 Bacterial SH3 domain RVT_3 PF13456.6 ETZ05341.1 - 0.0019 18.0 0.2 0.013 15.3 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase-like SH3_16 PF18348.1 ETZ05341.1 - 0.0056 16.4 1.0 0.018 14.8 0.1 2.3 2 0 0 2 2 2 1 Bacterial dipeptidyl-peptidase Sh3 domain Toprim_4 PF13662.6 ETZ05342.1 - 4.9e-17 62.2 0.0 8.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 ETZ05342.1 - 2.1e-09 36.8 0.4 3.6e-09 36.0 0.4 1.3 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 ETZ05342.1 - 0.0046 17.2 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain YbaB_DNA_bd PF02575.16 ETZ05343.1 - 1.5e-22 79.7 0.8 1.7e-22 79.4 0.8 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Wtap PF17098.5 ETZ05343.1 - 0.089 12.7 1.0 0.087 12.7 1.0 1.3 1 1 0 1 1 1 0 WTAP/Mum2p family ABC_tran PF00005.27 ETZ05344.1 - 9.3e-23 81.3 0.0 1.5e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ05344.1 - 2.1e-05 24.5 1.1 0.0011 18.9 0.2 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETZ05344.1 - 0.00035 20.3 1.0 0.0007 19.3 1.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ05344.1 - 0.00048 20.7 1.7 0.00048 20.7 1.7 1.7 2 1 0 2 2 1 1 AAA domain SMC_N PF02463.19 ETZ05344.1 - 0.0025 17.3 3.5 0.055 12.9 1.1 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ETZ05344.1 - 0.004 17.2 0.1 0.0083 16.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 ETZ05344.1 - 0.0052 17.0 0.4 0.21 11.8 0.4 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ETZ05344.1 - 0.012 15.4 1.7 0.015 15.0 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 ETZ05344.1 - 0.012 14.4 0.7 0.028 13.2 0.3 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ETZ05344.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 ETZ05344.1 - 0.028 14.7 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETZ05344.1 - 0.032 13.9 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ETZ05344.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 ETZ05344.1 - 0.058 13.8 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ETZ05344.1 - 0.079 12.3 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 ETZ05344.1 - 0.11 12.9 0.1 0.9 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 ETZ05344.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Dynamin family VirE PF05272.11 ETZ05344.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA_33 PF13671.6 ETZ05344.1 - 0.16 12.1 0.1 0.37 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETZ05344.1 - 0.18 11.0 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Pox_A32 PF04665.12 ETZ05344.1 - 0.22 11.0 2.3 0.51 9.8 0.0 2.3 3 0 0 3 3 3 0 Poxvirus A32 protein Ribosomal_L31 PF01197.18 ETZ05345.1 - 9.2e-20 70.7 0.2 1.1e-19 70.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 Rsbr_N PF08678.10 ETZ05346.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Rsbr N terminal SPOR PF05036.13 ETZ05347.1 - 0.0035 17.7 0.1 0.0066 16.8 0.1 1.4 1 0 0 1 1 1 1 Sporulation related domain PP1_bind PF15276.6 ETZ05347.1 - 0.12 12.7 1.3 0.51 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein phosphatase 1 binding HTH_Tnp_IS630 PF01710.16 ETZ05348.1 - 3.1e-06 27.2 0.0 3.4e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.16 ETZ05349.1 - 0.0053 16.8 0.1 0.0081 16.2 0.1 1.4 1 1 0 1 1 1 1 Transposase GCR1_C PF12550.8 ETZ05349.1 - 0.05 13.9 0.4 0.054 13.8 0.4 1.2 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Cytochrom_B558a PF05038.13 ETZ05352.1 - 0.26 10.8 7.4 0.39 10.3 0.7 2.3 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Hid1 PF12722.7 ETZ05352.1 - 7.4 4.6 19.5 9 4.3 19.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GTP_EFTU PF00009.27 ETZ05353.1 - 3.8e-70 235.4 0.0 6e-70 234.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ETZ05353.1 - 2e-41 140.6 0.1 3.6e-41 139.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ETZ05353.1 - 4.3e-33 113.3 0.1 8.1e-33 112.3 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ETZ05353.1 - 4e-30 103.7 0.1 1.1e-29 102.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETZ05353.1 - 2.5e-17 63.0 0.3 1.3e-16 60.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ETZ05353.1 - 6.8e-07 29.2 0.0 1.9e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ETZ05353.1 - 0.00013 22.0 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ETZ05353.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Pro_Al_protease PF02983.14 ETZ05353.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Response_reg PF00072.24 ETZ05354.1 - 9.6e-11 41.8 0.0 6.5e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain tRNA-synt_1 PF00133.22 ETZ05355.1 - 1.4e-170 568.5 0.0 1.7e-170 568.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ETZ05355.1 - 5.6e-21 74.7 0.4 2.1e-10 39.9 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETZ05355.1 - 4.4e-16 59.2 0.0 9.2e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ETZ05355.1 - 3.7e-06 26.5 0.0 0.084 12.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 ETZ05355.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 ETZ05355.1 - 0.0022 17.0 0.0 0.0058 15.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.14 ETZ05355.1 - 0.15 11.9 6.1 0.33 10.8 6.1 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS YpsA PF06908.11 ETZ05357.1 - 0.016 15.2 5.2 0.66 10.0 1.4 2.3 1 1 1 2 2 2 0 YspA SLOG family DUF4460 PF14687.6 ETZ05357.1 - 0.025 14.6 3.9 0.099 12.7 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4460) NDK PF00334.19 ETZ05359.1 - 4.4e-36 123.9 0.0 5e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HTH_23 PF13384.6 ETZ05361.1 - 2.5e-05 23.9 0.3 4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ05361.1 - 5e-05 23.3 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 ETZ05361.1 - 9.7e-05 22.1 0.3 0.001 18.8 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 ETZ05361.1 - 0.0002 21.3 0.1 0.00041 20.3 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix GerE PF00196.19 ETZ05361.1 - 0.0063 16.0 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family DUF1670 PF07900.11 ETZ05361.1 - 0.0094 15.3 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1670) Sigma70_r4_2 PF08281.12 ETZ05361.1 - 0.016 14.8 0.1 0.03 14.0 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 ETZ05361.1 - 0.025 14.2 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 ETZ05361.1 - 0.062 13.8 0.2 0.11 13.0 0.2 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2285 PF10074.9 ETZ05361.1 - 0.066 13.9 0.1 0.078 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) OMP_b-brl PF13505.6 ETZ05362.1 - 9.4e-08 32.4 5.3 3.7e-06 27.2 0.1 2.8 1 1 1 2 2 2 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ05362.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 OmpA-like transmembrane domain RimM PF01782.18 ETZ05363.1 - 5.9e-12 45.6 0.0 9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RimM N-terminal domain DDE_Tnp_IS1 PF03400.13 ETZ05365.1 - 0.067 13.5 0.0 0.075 13.4 0.0 1.1 1 0 0 1 1 1 0 IS1 transposase YchF-GTPase_C PF06071.13 ETZ05366.1 - 1.7e-39 133.8 0.8 3.2e-39 133.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ETZ05366.1 - 2.1e-23 82.6 0.0 5.4e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ05366.1 - 2.9e-08 33.4 0.1 2.5e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ETZ05366.1 - 0.069 13.2 0.2 8.6 6.4 0.0 2.7 2 1 1 3 3 3 0 Dynamin family Ribosomal_L19 PF01245.20 ETZ05367.1 - 5.8e-39 132.5 0.7 7e-39 132.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Holin_BhlA PF10960.8 ETZ05368.1 - 0.086 12.8 0.2 0.1 12.6 0.2 1.1 1 0 0 1 1 1 0 BhlA holin family Rick_17kDa_Anti PF05433.15 ETZ05369.1 - 6.5e-08 32.3 20.6 9.2e-08 31.8 20.6 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 ETZ05369.1 - 9.4e-07 28.7 11.0 1.4e-06 28.2 11.0 1.3 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 ETZ05369.1 - 0.0021 17.8 0.2 0.0029 17.3 0.2 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein 17kDa_Anti_2 PF16998.5 ETZ05369.1 - 0.0035 17.2 0.2 0.0048 16.8 0.2 1.2 1 0 0 1 1 1 1 17 kDa outer membrane surface antigen Gly-zipper_YMGG PF13441.6 ETZ05369.1 - 0.021 14.5 17.3 0.031 14.0 17.3 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Peptidase_A8 PF01252.18 ETZ05369.1 - 0.045 14.0 0.9 2.5 8.3 0.9 2.1 1 1 0 1 1 1 0 Signal peptidase (SPase) II LPAM_1 PF08139.12 ETZ05369.1 - 0.11 13.1 0.7 0.26 11.8 0.7 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Tim17 PF02466.19 ETZ05369.1 - 0.12 12.8 2.8 0.24 11.8 0.0 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 ETZ05369.1 - 3.1 8.0 13.7 5.5 7.2 13.7 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide G6B PF15096.6 ETZ05370.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 G6B family Elongin_A PF06881.11 ETZ05370.1 - 0.27 11.8 10.5 2.9 8.5 5.0 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Kinase-PPPase PF03618.14 ETZ05372.1 - 0.012 15.4 0.6 0.012 15.4 0.6 1.5 1 1 0 1 1 1 0 Kinase/pyrophosphorylase Vps51 PF08700.11 ETZ05372.1 - 0.052 13.6 0.7 0.052 13.6 0.7 2.8 3 0 0 3 3 3 0 Vps51/Vps67 FliG_M PF14841.6 ETZ05372.1 - 0.11 12.8 4.2 0.13 12.5 1.4 2.4 2 0 0 2 2 2 0 FliG middle domain DUF948 PF06103.11 ETZ05372.1 - 0.19 12.0 3.8 11 6.4 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PTPA PF03095.15 ETZ05372.1 - 1.3 8.4 8.9 5.1 6.5 0.6 2.1 1 1 1 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein NPV_P10 PF05531.12 ETZ05372.1 - 1.5 9.4 7.1 0.63 10.5 1.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3870 PF12986.7 ETZ05372.1 - 1.8 8.9 7.1 0.19 12.0 1.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3870) Med21 PF11221.8 ETZ05374.1 - 4.4e-05 23.8 10.2 6.1e-05 23.3 10.2 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex CCDC53 PF10152.9 ETZ05374.1 - 0.0018 18.7 7.1 0.0018 18.7 7.1 2.1 1 1 1 2 2 2 1 Subunit CCDC53 of WASH complex Tropomyosin_1 PF12718.7 ETZ05374.1 - 0.0027 17.8 11.1 0.0081 16.3 11.2 1.6 1 1 0 1 1 1 1 Tropomyosin like Laminin_II PF06009.12 ETZ05374.1 - 0.0072 16.3 6.1 0.011 15.7 6.1 1.3 1 0 0 1 1 1 1 Laminin Domain II Peptidase_S64 PF08192.11 ETZ05374.1 - 0.011 14.3 4.8 0.012 14.1 4.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3450 PF11932.8 ETZ05374.1 - 0.013 14.8 5.5 0.016 14.5 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BCDHK_Adom3 PF10436.9 ETZ05374.1 - 0.015 15.2 2.1 0.021 14.6 1.9 1.3 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HOOK PF05622.12 ETZ05374.1 - 0.015 13.5 10.0 0.017 13.3 10.0 1.1 1 0 0 1 1 1 0 HOOK protein HSCB_C PF07743.13 ETZ05374.1 - 0.041 14.4 1.3 0.041 14.4 1.3 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain APG6_N PF17675.1 ETZ05374.1 - 0.043 14.3 9.5 0.056 14.0 9.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CEP63 PF17045.5 ETZ05374.1 - 0.052 13.4 9.7 0.048 13.6 8.8 1.3 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa RasGEF_N_2 PF14663.6 ETZ05374.1 - 0.065 13.6 2.0 0.088 13.2 2.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sec34 PF04136.15 ETZ05374.1 - 0.12 12.3 7.2 0.44 10.4 7.2 1.9 1 1 0 1 1 1 0 Sec34-like family Fungal_TACC PF12709.7 ETZ05374.1 - 0.19 12.2 9.1 0.22 12.0 8.2 1.5 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF641 PF04859.12 ETZ05374.1 - 0.21 11.9 6.0 0.32 11.3 6.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) PP2C_C PF07830.13 ETZ05374.1 - 0.27 11.7 6.7 0.061 13.8 2.0 2.1 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Prefoldin_2 PF01920.20 ETZ05374.1 - 0.31 11.0 14.1 0.44 10.5 4.4 2.4 1 1 1 2 2 2 0 Prefoldin subunit ATG16 PF08614.11 ETZ05374.1 - 0.39 10.9 10.6 0.53 10.5 10.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 ETZ05374.1 - 0.72 10.3 7.5 0.61 10.5 3.8 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 ETZ05374.1 - 2 8.5 5.6 7 6.7 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 ETZ05374.1 - 2.9 8.3 16.5 1.5 9.3 5.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 ETZ05374.1 - 8.8 5.5 10.3 6.3 5.9 8.8 1.5 1 1 1 2 2 2 0 TMPIT-like protein HTH_23 PF13384.6 ETZ05375.1 - 9.6e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ05375.1 - 0.00078 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 ETZ05375.1 - 0.0031 17.6 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 ETZ05375.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.6 1 1 1 2 2 2 1 HTH domain Sigma70_r4_2 PF08281.12 ETZ05375.1 - 0.013 15.2 0.1 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_psq PF05225.16 ETZ05375.1 - 0.029 14.1 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_6 PF01418.17 ETZ05375.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family GcrA PF07750.11 ETZ05375.1 - 0.056 13.8 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_24 PF13412.6 ETZ05375.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DmpG_comm PF07836.11 ETZ05375.1 - 0.065 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 DmpG-like communication domain HTH_AsnC-type PF13404.6 ETZ05375.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GerE PF00196.19 ETZ05375.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 ETZ05375.1 - 0.097 12.8 0.1 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0122 PF04297.14 ETZ05375.1 - 0.1 12.8 0.0 0.42 10.9 0.0 1.7 1 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_50 PF18024.1 ETZ05375.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 ETZ05375.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_AraC PF00165.23 ETZ05375.1 - 0.19 11.9 0.4 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Peptidase_C42 PF05533.12 ETZ05376.1 - 0.032 14.2 0.3 0.046 13.8 0.3 1.3 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 ATG16 PF08614.11 ETZ05377.1 - 0.011 15.9 2.4 0.011 15.9 2.4 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Mucin PF01456.17 ETZ05377.1 - 0.13 12.3 11.8 2.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Tropomyosin_1 PF12718.7 ETZ05377.1 - 1.7 8.8 13.3 0.097 12.8 8.0 1.6 2 0 0 2 2 2 0 Tropomyosin like EF-G-binding_N PF07299.11 ETZ05378.1 - 0.001 19.6 2.6 0.001 19.6 2.6 1.9 2 0 0 2 2 2 1 Elongation factor G-binding protein, N-terminal DHR10 PF18595.1 ETZ05378.1 - 1.4 9.0 16.5 0.16 12.0 8.2 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Noelin-1 PF12308.8 ETZ05378.1 - 1.8 8.6 8.8 0.51 10.3 5.5 1.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein Bcr-Abl_Oligo PF09036.10 ETZ05378.1 - 7 6.7 10.3 0.3 11.1 0.5 2.7 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Exonuc_VII_L PF02601.15 ETZ05378.1 - 9.9 5.6 9.9 14 5.2 9.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CRA PF06589.11 ETZ05379.1 - 0.0019 18.3 1.1 0.0024 18.0 1.1 1.1 1 0 0 1 1 1 1 Circumsporozoite-related antigen (CRA) HTH_23 PF13384.6 ETZ05383.1 - 3.8e-05 23.3 0.0 5.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ05383.1 - 0.0019 17.9 0.0 0.0032 17.2 0.0 1.4 1 1 1 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 ETZ05383.1 - 0.0079 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 ETZ05383.1 - 0.012 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 ETZ05383.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_psq PF05225.16 ETZ05383.1 - 0.018 14.7 0.1 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 helix-turn-helix, Psq domain TetR_N PF00440.23 ETZ05383.1 - 0.031 14.1 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family GerE PF00196.19 ETZ05383.1 - 0.044 13.3 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_11 PF08279.12 ETZ05383.1 - 0.047 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.12 ETZ05383.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Bac_GH3_C PF18034.1 ETZ05383.1 - 0.084 12.6 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain HTH_AsnC-type PF13404.6 ETZ05383.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_ECF PF07638.11 ETZ05383.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 ECF sigma factor CENP-B_N PF04218.13 ETZ05383.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_19 PF12844.7 ETZ05383.1 - 0.18 11.8 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Pyr_redox_2 PF07992.14 ETZ05385.1 - 9e-53 179.4 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ETZ05385.1 - 1e-28 99.8 0.0 2.4e-28 98.6 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ETZ05385.1 - 3.5e-18 65.9 0.7 4.4e-15 56.0 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETZ05385.1 - 9.9e-11 41.4 6.3 0.0033 16.7 0.5 3.9 3 1 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETZ05385.1 - 3.9e-09 36.6 0.3 0.0012 19.0 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETZ05385.1 - 3.2e-06 26.8 0.1 4.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETZ05385.1 - 5.6e-06 25.7 1.1 4.2e-05 22.8 0.0 2.5 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETZ05385.1 - 2.1e-05 23.8 3.6 0.0032 16.6 1.2 2.9 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 ETZ05385.1 - 2.1e-05 23.4 5.8 0.00048 19.0 0.6 3.0 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 ETZ05385.1 - 0.0037 16.6 1.0 0.26 10.6 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ETZ05385.1 - 0.0096 15.3 0.1 0.25 10.7 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ETZ05385.1 - 0.0099 15.2 1.3 3.2 6.9 0.1 2.9 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 ETZ05385.1 - 0.13 11.8 7.7 4.8 6.7 2.1 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETZ05385.1 - 0.17 10.9 0.8 9.7 5.1 0.6 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ETZ05385.1 - 0.18 10.6 0.3 0.28 10.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DsbB PF02600.16 ETZ05386.1 - 8.6e-14 52.2 7.4 1.1e-13 51.8 7.4 1.1 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB Afaf PF15339.6 ETZ05386.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor ImcF-related_N PF14331.6 ETZ05387.1 - 0.046 13.1 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain HTH_40 PF14493.6 ETZ05387.1 - 0.053 14.0 4.9 3.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain DUF1977 PF09320.11 ETZ05387.1 - 0.44 10.8 3.9 9.6 6.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) PseudoU_synth_2 PF00849.22 ETZ05388.1 - 4.7e-29 101.5 0.0 8e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ETZ05388.1 - 0.0021 17.7 0.1 0.0093 15.7 0.0 2.1 2 0 0 2 2 2 1 S4 domain DNA_ligase_aden PF01653.18 ETZ05391.1 - 2.2e-103 345.7 0.0 3e-103 345.2 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 ETZ05391.1 - 3.3e-31 107.0 0.6 6.9e-31 106.0 0.6 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 ETZ05391.1 - 1.9e-11 43.9 0.1 3.3e-10 39.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.26 ETZ05391.1 - 2e-11 44.1 0.0 4.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 ETZ05391.1 - 2.2e-07 30.8 1.7 4e-07 29.9 1.7 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain HHH_5 PF14520.6 ETZ05391.1 - 3.7e-07 30.6 0.0 0.0029 18.2 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 ETZ05391.1 - 3.6e-05 23.6 0.1 9.2e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain RNA_ligase PF09414.10 ETZ05391.1 - 0.0082 16.5 0.9 0.027 14.8 0.0 2.2 2 0 0 2 2 2 1 RNA ligase NFRKB_winged PF14465.6 ETZ05392.1 - 0.12 12.6 2.2 0.17 12.1 0.3 2.1 2 0 0 2 2 2 0 NFRKB Winged Helix-like RILP PF11461.8 ETZ05392.1 - 1.5 9.1 9.8 0.14 12.4 0.8 2.7 3 0 0 3 3 3 0 Rab interacting lysosomal protein MMtag PF10159.9 ETZ05392.1 - 3.7 7.9 6.9 0.45 10.8 1.4 2.3 2 0 0 2 2 2 0 Multiple myeloma tumor-associated TSC22 PF01166.18 ETZ05393.1 - 0.067 13.5 0.1 0.084 13.2 0.1 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Meiotic_rec114 PF03525.14 ETZ05394.1 - 0.0053 15.8 2.7 0.0068 15.4 2.7 1.2 1 0 0 1 1 1 1 Meiotic recombination protein rec114 Oxidored_nitro PF00148.19 ETZ05394.1 - 0.098 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CRR7 PF12095.8 ETZ05394.1 - 0.13 12.8 4.6 1.8 9.1 0.1 2.2 1 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DAAD PF18752.1 ETZ05394.1 - 0.14 11.9 3.9 0.17 11.7 3.9 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase DUF3801 PF12687.7 ETZ05394.1 - 3.9 7.5 12.3 0.11 12.5 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) DDE_3 PF13358.6 ETZ05395.1 - 9.5e-14 51.4 0.1 9.5e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 ETZ05396.1 - 4.5e-15 55.7 0.0 6.2e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r3 PF04539.16 ETZ05397.1 - 2e-23 82.3 2.9 3.1e-23 81.7 0.1 2.9 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 ETZ05397.1 - 8.4e-22 76.7 0.5 1.6e-21 75.9 0.5 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ETZ05397.1 - 2.3e-16 59.0 3.4 2.3e-16 59.0 3.4 3.4 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 ETZ05397.1 - 5e-13 48.8 7.0 7.9e-13 48.2 0.0 3.7 3 0 0 3 3 3 1 Sigma-70 factor, region 1.2 Sigma70_ner PF04546.13 ETZ05397.1 - 1.6e-09 38.0 14.6 2.1e-08 34.3 11.3 3.3 2 1 0 2 2 2 1 Sigma-70, non-essential region Sigma70_r1_1 PF03979.14 ETZ05397.1 - 0.0064 16.5 1.7 0.0064 16.5 1.7 3.3 4 0 0 4 4 4 1 Sigma-70 factor, region 1.1 HTH_25 PF13413.6 ETZ05397.1 - 0.057 13.3 2.1 49 3.9 0.1 3.9 3 0 0 3 3 3 0 Helix-turn-helix domain zf-CHC2 PF01807.20 ETZ05398.1 - 1.8e-34 117.5 0.1 3.4e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_N PF08275.11 ETZ05398.1 - 6.8e-29 100.5 0.2 1.4e-28 99.5 0.2 1.5 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain Toprim_2 PF13155.6 ETZ05398.1 - 2.5e-08 34.3 0.0 9.3e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Toprim-like Toprim_4 PF13662.6 ETZ05398.1 - 8.4e-08 32.6 0.0 2.1e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 ETZ05398.1 - 0.002 18.5 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Toprim domain Toprim PF01751.22 ETZ05398.1 - 0.079 13.2 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Toprim domain eIF-1a PF01176.19 ETZ05400.1 - 5.8e-19 67.7 0.0 6.5e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF4537 PF15057.6 ETZ05400.1 - 0.0024 17.9 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) RsgA_N PF16745.5 ETZ05400.1 - 0.0039 16.9 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain Peptidase_M99_m PF17130.4 ETZ05400.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 DNA_topoisoIV PF00521.20 ETZ05401.1 - 9.5 5.0 8.7 0.39 9.5 2.1 2.0 3 0 0 3 3 3 0 DNA gyrase/topoisomerase IV, subunit A Biotin_lipoyl PF00364.22 ETZ05402.1 - 1.3e-16 60.2 0.1 2e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ETZ05402.1 - 4.4e-06 26.4 0.1 0.0063 16.3 0.0 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 ETZ05402.1 - 3e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 ETZ05402.1 - 0.0007 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 ETZ05402.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Glucosaminidase PF01832.20 ETZ05403.1 - 2.9e-12 46.9 0.0 4.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DnaB_2 PF07261.11 ETZ05403.1 - 0.16 11.8 4.1 15 5.4 0.1 3.8 4 1 0 4 4 4 0 Replication initiation and membrane attachment NifU PF01106.17 ETZ05404.1 - 3.5e-24 84.7 0.6 4.8e-24 84.3 0.0 1.5 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 ETZ05404.1 - 2.3e-18 66.0 0.0 3.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Peptidase_M20 PF01546.28 ETZ05405.1 - 4.5e-35 121.2 0.0 5.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETZ05405.1 - 3.4e-15 55.9 0.0 2.3e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Radical_SAM PF04055.21 ETZ05406.1 - 1.5e-18 67.7 0.0 3.3e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ETZ05406.1 - 4.5e-14 52.3 0.2 1.6e-13 50.5 0.2 1.9 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 URO-D PF01208.17 ETZ05406.1 - 0.039 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) HTH_23 PF13384.6 ETZ05407.1 - 9.5e-07 28.4 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ05407.1 - 0.0011 19.1 0.2 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 ETZ05407.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 ETZ05407.1 - 0.0019 17.9 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 ETZ05407.1 - 0.0026 17.7 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 HTH domain Terminase_5 PF06056.12 ETZ05407.1 - 0.0047 16.8 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_4 PF13613.6 ETZ05407.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4_2 PF08281.12 ETZ05407.1 - 0.007 16.0 0.1 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 TnsD PF15978.5 ETZ05407.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_24 PF13412.6 ETZ05407.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_IS630 PF01710.16 ETZ05407.1 - 0.029 14.4 0.2 0.094 12.8 0.2 1.7 1 1 0 1 1 1 0 Transposase HTH_6 PF01418.17 ETZ05407.1 - 0.032 14.2 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_psq PF05225.16 ETZ05407.1 - 0.051 13.3 0.1 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_29 PF13551.6 ETZ05407.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 ETZ05407.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 Transposase CTD_bind PF04818.13 ETZ05408.1 - 0.17 12.7 0.6 0.17 12.7 0.6 3.0 3 1 0 3 3 3 0 RNA polymerase II-binding domain. E1-E2_ATPase PF00122.20 ETZ05408.1 - 0.19 11.2 0.5 0.42 10.1 0.3 1.6 1 1 0 1 1 1 0 E1-E2 ATPase Phage_ABA_S PF18066.1 ETZ05408.1 - 0.51 11.1 5.5 3 8.6 1.1 3.0 1 1 1 2 2 2 0 Phage ABA sandwich domain ZnuA PF01297.17 ETZ05408.1 - 0.57 9.5 6.4 0.094 12.1 2.8 1.6 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DDE_3 PF13358.6 ETZ05409.1 - 0.00016 21.4 0.0 0.00019 21.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve_2 PF13333.6 ETZ05410.1 - 7.3e-06 26.1 0.1 1.1e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ETZ05410.1 - 0.00052 19.7 0.1 0.00076 19.2 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DUF3806 PF12713.7 ETZ05411.1 - 0.031 14.0 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) DUF2833 PF11090.8 ETZ05412.1 - 0.22 11.9 1.4 5.1 7.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) NLE PF08154.12 ETZ05412.1 - 4 8.0 7.3 19 5.8 0.2 3.8 4 0 0 4 4 4 0 NLE (NUC135) domain Presenilin PF01080.17 ETZ05412.1 - 8.4 5.0 12.5 15 4.3 12.5 1.4 1 0 0 1 1 1 0 Presenilin Spt5_N PF11942.8 ETZ05412.1 - 9.6 7.3 10.8 2.5 9.1 6.4 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4096 PF13340.6 ETZ05413.1 - 2.6e-10 40.4 0.0 2.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DRE2_N PF16803.5 ETZ05414.1 - 0.077 13.2 1.0 1.6 9.0 0.2 3.4 2 1 1 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus GP24_25 PF17388.2 ETZ05414.1 - 0.43 10.6 2.9 5.1 7.1 0.1 3.7 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 EIF_2_alpha PF07541.12 ETZ05414.1 - 2.4 8.3 8.7 11 6.2 0.2 4.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit Acyl_transf_1 PF00698.21 ETZ05416.1 - 1.9e-38 132.8 0.0 2.3e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain MAGI_u5 PF16666.5 ETZ05416.1 - 0.17 12.1 0.1 0.27 11.4 0.1 1.2 1 0 0 1 1 1 0 Unstructured region on MAGI polyprenyl_synt PF00348.17 ETZ05417.1 - 1.4e-47 161.9 0.0 1.8e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HAD_2 PF13419.6 ETZ05418.1 - 1.4e-12 48.1 0.0 1.9e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ05418.1 - 4.4e-05 23.9 0.0 0.0001 22.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HTH_23 PF13384.6 ETZ05419.1 - 0.022 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 ETZ05419.1 - 0.07 12.9 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_6 PF01418.17 ETZ05419.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family P22_Cro PF14549.6 ETZ05419.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_23 PF13384.6 ETZ05425.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ05425.1 - 0.00069 19.3 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ETZ05425.1 - 0.00074 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 ETZ05425.1 - 0.00076 19.1 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 ETZ05425.1 - 0.00077 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain GerE PF00196.19 ETZ05425.1 - 0.004 16.7 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 ETZ05425.1 - 0.0073 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_50 PF18024.1 ETZ05425.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ETZ05425.1 - 0.02 14.8 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_Tnp_4 PF13613.6 ETZ05425.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_40 PF14493.6 ETZ05425.1 - 0.035 14.5 0.0 0.069 13.6 0.0 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 ETZ05425.1 - 0.038 13.7 0.1 0.095 12.5 0.1 1.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 ETZ05425.1 - 0.045 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 ETZ05425.1 - 0.046 13.8 0.0 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix Sigma70_r4 PF04545.16 ETZ05425.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 ETZ05425.1 - 0.078 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 ETZ05425.1 - 0.092 12.6 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor DmpG_comm PF07836.11 ETZ05425.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 DmpG-like communication domain TetR_N PF00440.23 ETZ05425.1 - 0.13 12.1 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family UPF0122 PF04297.14 ETZ05425.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like GcrA PF07750.11 ETZ05425.1 - 0.16 12.3 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator DNA_alkylation PF08713.11 ETZ05426.1 - 4e-59 199.9 0.5 4.6e-59 199.7 0.5 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF4158 PF13700.6 ETZ05426.1 - 0.0087 15.9 0.5 0.015 15.1 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4158) SSPI PF14098.6 ETZ05426.1 - 1 9.6 4.5 19 5.5 0.1 3.0 3 0 0 3 3 3 0 Small, acid-soluble spore protein I Inhibitor_I29 PF08246.12 ETZ05426.1 - 1.2 9.7 4.4 2 8.9 3.9 1.7 1 1 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) DNA_binding_1 PF01035.20 ETZ05427.1 - 1.8e-28 98.5 0.1 3.1e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF1400 PF07176.11 ETZ05428.1 - 0.073 13.4 0.9 1 9.6 0.0 3.4 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) UNC45-central PF11701.8 ETZ05428.1 - 0.16 11.9 1.2 2.6 8.0 0.1 3.3 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central GP24_25 PF17388.2 ETZ05428.1 - 0.9 9.5 9.0 0.86 9.6 2.1 3.4 3 1 0 3 3 3 0 Tail assembly gene products 24 & 25 HTH_38 PF13936.6 ETZ05429.1 - 0.00014 21.5 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ETZ05429.1 - 0.0004 20.1 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 ETZ05429.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_AsnC-type PF13404.6 ETZ05429.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ETZ05429.1 - 0.038 13.9 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 ETZ05429.1 - 0.047 13.8 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ETZ05429.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 HTH domain HTH_psq PF05225.16 ETZ05429.1 - 0.1 12.4 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain TetR_N PF00440.23 ETZ05429.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.12 ETZ05429.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Bac_GH3_C PF18034.1 ETZ05429.1 - 0.18 11.6 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain DDE_3 PF13358.6 ETZ05430.1 - 5.2e-20 71.7 0.0 5.8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 ETZ05430.1 - 0.0062 16.7 0.0 0.0079 16.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF1103 PF06513.11 ETZ05431.1 - 7.4e-06 25.7 0.2 1.1e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF5344 PF17279.2 ETZ05431.1 - 0.001 19.6 1.3 3.4 8.3 0.1 3.8 3 2 1 4 4 4 2 Family of unknown function (DUF5344) SMK-1 PF04802.15 ETZ05431.1 - 0.0067 16.3 0.8 1.1 9.1 0.1 2.8 1 1 1 2 2 2 2 Component of IIS longevity pathway SMK-1 Phage_cap_E PF03864.15 ETZ05431.1 - 0.0077 15.4 1.9 35 3.4 0.0 4.6 3 2 2 5 5 5 0 Phage major capsid protein E Cohesin_HEAT PF12765.7 ETZ05431.1 - 0.029 14.7 0.3 75 3.8 0.0 4.1 4 1 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion FDF PF09532.10 ETZ05431.1 - 0.11 13.4 3.8 14 6.6 0.0 4.1 1 1 3 4 4 4 0 FDF domain Npun_R1517 PF18068.1 ETZ05431.1 - 0.13 12.6 9.5 7.4 7.0 0.7 3.1 3 0 0 3 3 3 0 Npun R1517 EamA PF00892.20 ETZ05432.1 - 1.4e-19 70.6 37.9 3.7e-10 40.1 14.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ETZ05432.1 - 9.8e-06 25.1 11.1 9.8e-06 25.1 11.1 2.4 1 1 1 2 2 2 2 Triose-phosphate Transporter family Ribonuclease_P PF00825.18 ETZ05433.1 - 8.3e-09 35.5 0.3 1.1e-08 35.2 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease P DUF3870 PF12986.7 ETZ05433.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) YidC_periplas PF14849.6 ETZ05434.1 - 1.6e-56 192.3 0.2 2e-56 192.0 0.2 1.1 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 ETZ05434.1 - 1.1e-50 171.7 8.1 1.7e-50 171.2 8.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2603 PF10788.9 ETZ05434.1 - 0.055 13.5 0.0 0.35 10.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2603) MMR_HSR1 PF01926.23 ETZ05436.1 - 2.1e-17 63.2 0.0 2.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ05436.1 - 2.5e-07 30.7 0.0 3.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ETZ05436.1 - 6.6e-07 29.0 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 ETZ05436.1 - 0.00011 21.9 0.1 0.0004 20.1 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 ETZ05436.1 - 0.00027 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 ETZ05436.1 - 0.0018 17.9 0.1 0.46 10.0 0.1 2.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Ras PF00071.22 ETZ05436.1 - 0.0031 17.1 0.1 0.31 10.6 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 ETZ05436.1 - 0.004 17.4 0.2 0.0071 16.6 0.2 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ETZ05436.1 - 0.0052 16.9 0.3 0.084 12.9 0.3 2.2 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 ETZ05436.1 - 0.015 15.3 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 ETZ05436.1 - 0.017 14.5 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 ETZ05436.1 - 0.03 14.9 0.0 0.041 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETZ05436.1 - 0.059 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 ETZ05436.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETZ05436.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MFS_1 PF07690.16 ETZ05437.1 - 6.5e-31 107.5 64.5 1.7e-27 96.3 34.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UvrD-helicase PF00580.21 ETZ05438.1 - 4.7e-66 223.4 0.0 7.7e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ETZ05438.1 - 8.3e-23 81.3 0.0 3.5e-22 79.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 ETZ05438.1 - 1.4e-22 80.5 0.0 2.9e-20 72.9 0.0 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 ETZ05438.1 - 9e-11 41.4 0.1 7.7e-05 22.4 0.1 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ETZ05438.1 - 8.1e-05 22.4 0.0 0.09 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETZ05438.1 - 0.0001 22.6 0.1 0.41 10.9 0.0 3.1 2 2 0 2 2 2 2 AAA domain PhoH PF02562.16 ETZ05438.1 - 0.0011 18.4 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.18 ETZ05438.1 - 0.0053 16.5 0.2 13 5.5 0.0 4.0 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ETZ05438.1 - 0.25 11.3 0.9 0.86 9.6 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit LexA_DNA_bind PF01726.16 ETZ05439.1 - 0.19 11.6 0.2 30 4.5 0.0 3.1 2 0 0 2 2 2 0 LexA DNA binding domain DNA_pol3_chi PF04364.13 ETZ05440.1 - 6e-14 52.4 0.5 7.9e-14 52.0 0.2 1.3 1 1 0 1 1 1 1 DNA polymerase III chi subunit, HolC NUDIX_5 PF16705.5 ETZ05441.1 - 0.018 14.8 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT LpxI_C PF06230.11 ETZ05442.1 - 1.7e-32 112.0 0.0 4e-32 110.9 0.0 1.6 2 0 0 2 2 2 1 LpxI C-terminal domain LpxI_N PF17930.1 ETZ05442.1 - 3.2e-26 91.7 0.0 5.3e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 LpxI N-terminal domain Pterin_4a PF01329.19 ETZ05442.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase CN_hydrolase PF00795.22 ETZ05443.1 - 2.3e-21 76.3 0.0 4.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LpxC PF03331.13 ETZ05445.1 - 1.4e-70 237.9 0.0 1.7e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Bac_GDH PF05088.12 ETZ05446.1 - 1.3e-198 662.7 0.2 2.2e-188 628.7 0.0 2.3 1 1 1 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 ETZ05446.1 - 4.2e-11 43.0 0.0 1.4e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ATP-synt_A PF00119.20 ETZ05447.1 - 4.4e-51 173.8 27.2 5.3e-51 173.6 27.2 1.0 1 0 0 1 1 1 1 ATP synthase A chain AAA_2 PF07724.14 ETZ05449.1 - 1.3e-55 188.1 0.0 3e-54 183.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ETZ05449.1 - 8.5e-35 118.8 0.6 8.5e-35 118.8 0.6 3.0 2 1 1 3 3 2 1 AAA lid domain ClpB_D2-small PF10431.9 ETZ05449.1 - 2.6e-25 88.3 0.1 1.4e-24 85.9 0.1 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ETZ05449.1 - 5.5e-24 85.1 0.0 9.6e-13 48.7 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETZ05449.1 - 2.6e-18 66.4 0.7 5.4e-12 45.9 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 ETZ05449.1 - 3.6e-11 43.0 5.9 2.2e-09 37.3 1.5 3.6 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 ETZ05449.1 - 6e-10 39.8 12.5 2.4e-05 24.8 0.1 5.0 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 ETZ05449.1 - 1.4e-08 35.1 8.2 0.011 16.0 0.1 5.5 4 2 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 ETZ05449.1 - 7.7e-07 29.0 0.0 0.0022 17.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 ETZ05449.1 - 1e-06 28.6 0.1 0.037 13.8 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_7 PF12775.7 ETZ05449.1 - 1.1e-06 28.3 0.0 0.0053 16.3 0.0 2.9 3 0 0 3 3 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 ETZ05449.1 - 3.5e-06 27.1 0.6 0.95 9.3 0.0 3.9 4 0 0 4 4 3 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 ETZ05449.1 - 5.6e-06 26.9 0.7 0.21 12.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain Mg_chelatase PF01078.21 ETZ05449.1 - 3.9e-05 23.1 0.0 0.28 10.5 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ETZ05449.1 - 5.1e-05 23.6 0.0 1.5 9.0 0.0 4.1 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 ETZ05449.1 - 0.00013 21.4 0.0 0.29 10.5 0.0 4.0 3 1 0 3 3 3 1 Bacterial TniB protein AAA_24 PF13479.6 ETZ05449.1 - 0.00015 21.6 0.0 0.66 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ETZ05449.1 - 0.00039 20.5 0.0 1.7 8.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 ETZ05449.1 - 0.00049 20.1 0.0 0.26 11.2 0.0 2.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 ETZ05449.1 - 0.0006 20.2 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 ETZ05449.1 - 0.00065 19.6 0.1 3.3 7.6 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase RuvB_N PF05496.12 ETZ05449.1 - 0.00076 19.3 3.6 2.1 8.1 0.0 4.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ETZ05449.1 - 0.00078 19.6 0.0 2.8 8.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ETZ05449.1 - 0.00092 19.2 0.0 2 8.4 0.0 2.9 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 ETZ05449.1 - 0.0012 19.1 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 ETZ05449.1 - 0.0013 18.0 0.6 0.36 9.9 0.0 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF815) ResIII PF04851.15 ETZ05449.1 - 0.008 16.2 0.3 16 5.5 0.0 4.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 ETZ05449.1 - 0.012 15.4 0.0 0.4 10.4 0.0 2.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_30 PF13604.6 ETZ05449.1 - 0.014 15.2 0.3 5.7 6.6 0.0 4.0 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 ETZ05449.1 - 0.018 15.6 1.0 2.2 8.8 0.0 3.6 3 1 1 4 4 3 0 ABC transporter Zeta_toxin PF06414.12 ETZ05449.1 - 0.021 14.1 0.0 6.2 6.0 0.0 3.3 3 0 0 3 3 2 0 Zeta toxin AAA_19 PF13245.6 ETZ05449.1 - 0.023 15.0 0.0 1 9.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 ETZ05449.1 - 0.026 14.1 0.1 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETZ05449.1 - 0.032 14.1 0.0 6.4 6.6 0.0 3.0 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.11 ETZ05449.1 - 0.068 13.0 0.0 21 5.0 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ETZ05449.1 - 0.071 12.9 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 ETZ05449.1 - 0.12 12.1 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 ETZ05449.1 - 0.42 11.1 0.0 0.42 11.1 0.0 3.9 3 2 1 4 4 2 0 AAA domain DUF87 PF01935.17 ETZ05449.1 - 1.4 9.0 9.7 3.9 7.5 0.0 4.6 5 0 0 5 5 5 0 Helicase HerA, central domain zf-C4H2 PF10146.9 ETZ05449.1 - 2.8 8.2 11.2 33 4.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein DUF1955 PF09205.10 ETZ05454.1 - 0.0063 16.3 3.2 0.0063 16.3 3.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1955) Peptidase_M24 PF00557.24 ETZ05455.1 - 9.5e-50 169.2 0.0 1.1e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DDE_Tnp_1 PF01609.21 ETZ05456.1 - 0.00011 21.9 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_2 PF04693.12 ETZ05456.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Toxin-deaminase PF14424.6 ETZ05456.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF1539 PF07560.11 ETZ05457.1 - 0.035 14.2 0.0 0.038 14.1 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Epimerase_2 PF02350.19 ETZ05458.1 - 2.6e-91 306.1 0.7 2.9e-91 305.9 0.7 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 ETZ05458.1 - 0.0018 18.8 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ETZ05458.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_tranf_2_2 PF10111.9 ETZ05459.1 - 0.0022 17.5 0.1 0.0025 17.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ETZ05459.1 - 0.0084 16.0 0.0 0.018 15.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ETZ05460.1 - 2.8e-25 89.1 0.1 3.2e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ETZ05460.1 - 2.9e-11 43.4 0.1 3.4e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 ETZ05460.1 - 0.0062 16.4 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MutS_IV PF05190.18 ETZ05460.1 - 0.074 13.4 0.1 0.14 12.5 0.0 1.7 2 1 0 2 2 2 0 MutS family domain IV Vac7 PF12751.7 ETZ05466.1 - 0.67 9.3 19.7 0.96 8.8 19.7 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 AAA_26 PF13500.6 ETZ05469.1 - 1.3e-42 145.9 0.1 1.6e-42 145.6 0.1 1.0 1 0 0 1 1 1 1 AAA domain Methyltransf_25 PF13649.6 ETZ05470.1 - 2.4e-09 37.8 0.0 4.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ05470.1 - 6.8e-08 33.1 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ05470.1 - 6.3e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ05470.1 - 1.1e-06 29.3 0.0 2.8e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ05470.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ETZ05470.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETZ05470.1 - 0.04 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 ETZ05470.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.7 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ETZ05470.1 - 0.07 12.5 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ETZ05470.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DDE_Tnp_1_2 PF13586.6 ETZ05471.1 - 0.00061 20.1 0.1 0.00073 19.9 0.1 1.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ETZ05471.1 - 0.00098 18.8 0.5 0.0018 17.9 0.5 1.5 1 1 0 1 1 1 1 Transposase DDE domain BTG PF07742.12 ETZ05473.1 - 0.074 12.9 0.5 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 BTG family NEMO PF11577.8 ETZ05473.1 - 3.6 7.7 6.0 1.1 9.3 0.1 2.9 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO DDE_Tnp_1 PF01609.21 ETZ05475.1 - 0.00053 19.7 0.0 0.00061 19.5 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Glyco_transf_25 PF01755.17 ETZ05476.1 - 1.3e-22 80.6 0.0 9.6e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Hfq PF17209.3 ETZ05477.1 - 6.4e-18 64.2 0.1 8.5e-18 63.8 0.1 1.1 1 0 0 1 1 1 1 Hfq protein HAD_2 PF13419.6 ETZ05478.1 - 3.9e-28 98.7 0.0 4.8e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ05478.1 - 1.3e-08 35.4 0.0 6.6e-05 23.3 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ETZ05478.1 - 2.2e-06 28.2 0.0 3.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETZ05478.1 - 0.0079 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2164 PF09932.9 ETZ05478.1 - 0.043 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Cu-oxidase_4 PF02578.15 ETZ05479.1 - 1.6e-39 135.9 0.0 1.9e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase DUF3785 PF12653.7 ETZ05479.1 - 0.27 11.3 2.9 0.45 10.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Thioredoxin PF00085.20 ETZ05480.1 - 2.1e-19 69.4 0.0 2.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ETZ05480.1 - 5.2e-08 33.3 0.0 1.4e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETZ05480.1 - 6.2e-08 32.9 0.1 3.2e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 ETZ05480.1 - 7.6e-07 29.2 0.0 9.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 ETZ05480.1 - 3.5e-05 23.6 0.0 4.6e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ETZ05480.1 - 0.00051 19.9 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 ETZ05480.1 - 0.00052 19.8 0.1 0.00068 19.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ETZ05480.1 - 0.00081 18.8 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ETZ05480.1 - 0.003 17.7 0.1 0.0045 17.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like KaiB PF07689.12 ETZ05480.1 - 0.0042 16.8 0.1 0.0054 16.4 0.1 1.3 1 0 0 1 1 1 1 KaiB domain DUF836 PF05768.14 ETZ05480.1 - 0.0049 17.2 0.0 0.006 17.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 ETZ05480.1 - 0.012 15.6 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.24 ETZ05480.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.7 1 1 1 2 2 2 0 Glutaredoxin CDC24_OB2 PF17245.2 ETZ05480.1 - 0.036 14.6 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 TrbC_Ftype PF09673.10 ETZ05480.1 - 0.052 13.6 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein MVP_shoulder PF11978.8 ETZ05481.1 - 0.13 12.3 3.1 6.2 6.9 1.2 2.4 2 0 0 2 2 2 0 Shoulder domain TetR_C_8 PF14278.6 ETZ05481.1 - 0.98 9.6 8.3 0.16 12.1 3.1 2.5 2 1 1 3 3 3 0 Transcriptional regulator C-terminal region HTH_33 PF13592.6 ETZ05482.1 - 0.00012 21.6 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_IS1 PF03400.13 ETZ05483.1 - 0.021 15.2 1.7 0.038 14.3 0.3 2.0 2 0 0 2 2 2 0 IS1 transposase MHC_I_C PF06623.11 ETZ05483.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 MHC_I C-terminus DDE_Tnp_1 PF01609.21 ETZ05485.1 - 0.021 14.5 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_IS240 PF13610.6 ETZ05485.1 - 0.071 13.3 0.0 0.084 13.1 0.0 1.1 1 0 0 1 1 1 0 DDE domain IZUMO PF15005.6 ETZ05487.1 - 0.1 13.1 0.2 0.5 10.9 0.2 2.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Clp_N PF02861.20 ETZ05487.1 - 0.21 11.8 0.3 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component ApoLp-III PF07464.11 ETZ05488.1 - 0.002 18.3 4.7 0.002 18.3 4.7 1.5 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF5129 PF17173.4 ETZ05488.1 - 0.012 14.8 1.4 0.013 14.7 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) NAD_binding_6 PF08030.12 ETZ05488.1 - 0.05 13.7 1.1 0.061 13.4 1.1 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FHIPEP PF00771.20 ETZ05488.1 - 0.46 8.9 2.0 0.71 8.3 2.0 1.3 1 1 0 1 1 1 0 FHIPEP family FAD_SOX PF18371.1 ETZ05488.1 - 0.53 10.7 2.5 1.5 9.2 0.6 2.4 1 1 2 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF2175 PF09943.9 ETZ05488.1 - 0.77 10.1 4.7 0.61 10.4 3.4 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Fib_alpha PF08702.10 ETZ05488.1 - 3.5 7.8 10.7 1.1 9.5 3.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FKBP_N PF01346.18 ETZ05488.1 - 3.5 8.6 7.2 2.1 9.3 5.0 1.7 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase UPF0242 PF06785.11 ETZ05488.1 - 3.6 7.6 15.4 7 6.7 15.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lip_A_acyltrans PF03279.13 ETZ05489.1 - 0.12 11.5 0.2 0.24 10.5 0.1 1.5 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase MFS_1 PF07690.16 ETZ05490.1 - 8.6e-09 34.8 28.9 8.6e-09 34.8 28.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2118 PF09891.9 ETZ05491.1 - 0.88 9.5 4.4 0.23 11.4 0.3 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) Mad3_BUB1_I_2 PF17014.5 ETZ05492.1 - 0.41 10.8 11.3 0.092 12.9 1.8 2.7 1 1 1 3 3 3 0 Putative Mad3/BUB1 like region 1 protein FeoB_Cyto PF17910.1 ETZ05492.1 - 7 7.3 10.2 1 10.0 3.8 2.8 1 1 1 2 2 2 0 FeoB cytosolic helical domain HTH_38 PF13936.6 ETZ05494.1 - 0.0017 18.0 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ETZ05494.1 - 0.008 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 ETZ05494.1 - 0.0096 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Bac_GH3_C PF18034.1 ETZ05494.1 - 0.019 14.7 0.0 0.021 14.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain HTH_11 PF08279.12 ETZ05494.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 HTH domain ABC_tran PF00005.27 ETZ05495.1 - 4.5e-33 114.7 0.0 6.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ05495.1 - 1.2e-09 38.5 0.6 7.8e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 ETZ05495.1 - 0.00019 21.2 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ETZ05495.1 - 0.00026 21.0 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 ETZ05495.1 - 0.002 18.5 0.0 0.012 16.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 ETZ05495.1 - 0.0048 16.4 0.0 0.2 11.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 ETZ05495.1 - 0.011 15.7 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ05495.1 - 0.012 16.0 0.1 0.017 15.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ETZ05495.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ05495.1 - 0.036 14.6 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETZ05495.1 - 0.036 14.3 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETZ05495.1 - 0.057 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 ETZ05495.1 - 0.058 12.6 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 ETZ05495.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Bac_DNA_binding PF00216.21 ETZ05496.1 - 2.1e-16 59.9 1.5 2.4e-16 59.7 1.5 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein Methyltransf_4 PF02390.17 ETZ05496.1 - 0.064 12.7 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF4096 PF13340.6 ETZ05497.1 - 0.01 16.0 0.1 0.16 12.2 0.1 2.1 1 1 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Terminase_6 PF03237.15 ETZ05498.1 - 2.1e-23 83.1 0.0 5.3e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Terminase-like family Terminase_6C PF17289.2 ETZ05498.1 - 3.2e-07 30.6 0.0 6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Terminase RNaseH-like domain Rtt106_N PF18215.1 ETZ05499.1 - 0.01 15.6 0.8 0.063 13.0 0.0 2.6 3 0 0 3 3 3 0 Histone chaperone Rtt106 N-terminal domain DALR_1 PF05746.15 ETZ05500.1 - 7.4e-20 71.3 0.0 2.2e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 ETZ05500.1 - 4.1e-18 65.4 0.1 1.4e-17 63.7 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 ETZ05500.1 - 2.7e-15 56.7 0.0 6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 ETZ05500.1 - 9.2e-11 41.6 0.3 0.00015 21.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ETZ05500.1 - 8e-08 31.4 0.3 0.00046 19.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 ETZ05500.1 - 2e-06 27.0 0.0 1.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 ETZ05500.1 - 0.00054 18.3 0.0 0.2 9.9 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) P22_Cro PF14549.6 ETZ05505.1 - 0.073 12.9 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_Tnp_4 PF13613.6 ETZ05505.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease YdaS_antitoxin PF15943.5 ETZ05505.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SKA2 PF16740.5 ETZ05506.1 - 0.0053 16.5 3.2 6.9 6.5 0.7 4.6 3 1 1 4 4 4 2 Spindle and kinetochore-associated protein 2 Atg14 PF10186.9 ETZ05506.1 - 0.018 14.2 1.4 0.043 12.9 1.4 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 ETZ05506.1 - 0.022 14.8 12.9 0.2 11.7 0.7 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Vps51 PF08700.11 ETZ05506.1 - 0.085 12.9 3.9 0.28 11.3 2.1 3.0 2 0 0 2 2 2 0 Vps51/Vps67 BAR PF03114.18 ETZ05506.1 - 0.21 11.2 3.7 1.9 8.1 0.1 3.0 2 1 1 3 3 3 0 BAR domain Mis14 PF08641.12 ETZ05506.1 - 0.23 11.8 2.7 0.75 10.1 2.5 2.1 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Cortex-I_coil PF09304.10 ETZ05506.1 - 0.62 10.3 3.1 5.2 7.3 0.1 3.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil HAP1_N PF04849.13 ETZ05506.1 - 0.78 8.9 6.1 1.5 7.9 4.2 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Allexi_40kDa PF05549.11 ETZ05506.1 - 0.87 9.1 11.9 1.5 8.2 4.0 3.1 2 2 1 3 3 3 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 ETZ05506.1 - 4.8 7.2 40.7 2.4 8.2 7.3 5.2 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus 7TMR-HDED PF07697.11 ETZ05506.1 - 8 6.5 16.3 29 4.7 12.7 2.9 1 1 0 2 2 2 0 7TM-HD extracellular DDE_Tnp_IS1 PF03400.13 ETZ05507.1 - 0.07 13.5 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 IS1 transposase HTH_23 PF13384.6 ETZ05508.1 - 0.00078 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ05508.1 - 0.0045 16.7 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.16 ETZ05508.1 - 0.011 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Sigma70_r4_2 PF08281.12 ETZ05508.1 - 0.017 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_ECF PF07638.11 ETZ05508.1 - 0.033 14.1 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor HTH_Tnp_4 PF13613.6 ETZ05508.1 - 0.041 13.6 0.1 0.087 12.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_19 PF12844.7 ETZ05508.1 - 0.052 13.6 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 ETZ05508.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ETZ05508.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 ETZ05508.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain Sigma70_r4 PF04545.16 ETZ05508.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 TetR_N PF00440.23 ETZ05508.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family UvrB_inter PF17757.1 ETZ05510.1 - 8.7e-28 96.3 0.0 2.8e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 ETZ05510.1 - 4.3e-19 68.9 0.5 2.2e-18 66.6 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UvrB PF12344.8 ETZ05510.1 - 1.2e-16 60.3 0.2 3.9e-16 58.6 0.1 1.9 1 1 1 2 2 2 1 Ultra-violet resistance protein B ResIII PF04851.15 ETZ05510.1 - 2.2e-12 47.3 0.0 2.2e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 ETZ05510.1 - 1.1e-08 34.6 3.3 1.9e-08 33.8 1.7 2.5 2 0 0 2 2 2 1 UvrB/uvrC motif DEAD PF00270.29 ETZ05510.1 - 3e-06 27.1 0.1 6.1e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ETZ05510.1 - 1.1e-05 25.3 0.0 0.00047 19.9 0.0 3.2 4 0 0 4 4 4 1 AAA domain Kinesin PF00225.23 ETZ05510.1 - 0.005 15.8 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain SWI2_SNF2 PF18766.1 ETZ05510.1 - 0.0062 16.2 0.0 0.072 12.7 0.0 2.6 3 0 0 3 3 3 1 SWI2/SNF2 ATPase Microtub_bd PF16796.5 ETZ05510.1 - 0.026 14.4 0.0 0.11 12.4 0.0 2.1 1 0 0 1 1 1 0 Microtubule binding AAA_22 PF13401.6 ETZ05510.1 - 0.038 14.3 0.2 1.4 9.2 0.0 3.2 2 1 1 3 3 3 0 AAA domain UB2H PF14814.6 ETZ05510.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 1 0 1 1 1 0 Bifunctional transglycosylase second domain AAA_7 PF12775.7 ETZ05510.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Col_cuticle_N PF01484.17 ETZ05510.1 - 0.2 11.7 0.0 0.66 10.1 0.0 2.0 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain UvrD-helicase PF00580.21 ETZ05510.1 - 0.85 9.1 3.8 9.5 5.6 0.1 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain HTH_Tnp_IS630 PF01710.16 ETZ05512.1 - 0.00041 20.4 0.1 0.00046 20.2 0.1 1.2 1 0 0 1 1 1 1 Transposase DUF1574 PF07611.11 ETZ05512.1 - 0.018 14.4 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Cas_APE2256 PF09651.10 ETZ05512.1 - 0.22 11.4 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) ETC_C1_NDUFA5 PF04716.14 ETZ05513.1 - 0.037 13.8 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 ETC complex I subunit conserved region CNOT1_HEAT PF16418.5 ETZ05514.1 - 0.44 10.6 11.1 1.8 8.7 0.5 4.5 4 1 0 4 4 4 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF5617 PF18493.1 ETZ05514.1 - 3.4 7.8 7.7 0.63 10.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5617) FMN_red PF03358.15 ETZ05516.1 - 7.6e-13 48.5 0.0 9.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ETZ05516.1 - 6.9e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Phage_integrase PF00589.22 ETZ05517.1 - 2.7e-34 118.4 0.0 4.1e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ETZ05517.1 - 8.1e-15 54.9 1.7 1.7e-13 50.7 0.4 3.1 3 1 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ETZ05517.1 - 1e-07 32.3 1.3 2e-07 31.4 0.4 2.0 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 ETZ05517.1 - 0.014 15.8 0.2 4.1 7.8 0.0 2.7 2 1 0 3 3 3 0 Phage integrase SAM-like domain Phage_integr_3 PF16795.5 ETZ05517.1 - 0.027 14.4 0.2 7.2 6.5 0.0 2.5 3 0 0 3 3 3 0 Archaeal phage integrase Glutaredoxin PF00462.24 ETZ05518.1 - 2.3e-14 53.3 0.0 3.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MS_channel PF00924.18 ETZ05521.1 - 7.1e-30 104.1 3.4 7.1e-30 104.1 3.4 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF2121 PF09894.9 ETZ05521.1 - 0.15 11.6 1.2 6.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) RNase_HII PF01351.18 ETZ05522.1 - 4.4e-31 108.3 0.0 5.1e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII GTP1_OBG PF01018.22 ETZ05526.1 - 1.1e-47 161.5 5.8 1.5e-47 161.1 5.8 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 ETZ05526.1 - 1.2e-29 102.7 0.0 2.1e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ05526.1 - 2.3e-15 56.4 0.0 3.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ETZ05526.1 - 4.5e-06 26.8 0.0 0.025 14.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family cobW PF02492.19 ETZ05526.1 - 0.00019 21.1 0.3 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 ETZ05526.1 - 0.00027 20.4 1.1 0.0015 18.0 1.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETZ05526.1 - 0.00071 19.2 0.1 0.54 9.8 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ETZ05526.1 - 0.00079 18.8 0.1 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 AIG1 family Gtr1_RagA PF04670.12 ETZ05526.1 - 0.0016 17.9 0.2 0.0029 17.0 0.2 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 ETZ05526.1 - 0.0024 18.4 0.7 0.011 16.2 0.7 2.1 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ETZ05526.1 - 0.0027 17.6 6.0 0.68 9.8 0.4 3.0 2 1 1 3 3 3 2 RsgA GTPase MeaB PF03308.16 ETZ05526.1 - 0.017 14.1 0.1 0.1 11.6 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 ETZ05526.1 - 0.025 14.6 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 ETZ05526.1 - 0.029 14.9 0.1 0.09 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 ETZ05526.1 - 0.05 13.0 0.0 0.095 12.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ETZ05526.1 - 0.061 13.6 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETZ05526.1 - 0.1 12.4 0.1 0.61 9.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 ETZ05526.1 - 0.13 12.0 0.1 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 ETZ05526.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 APH PF01636.23 ETZ05528.1 - 2.4e-06 27.7 0.3 3.1e-06 27.3 0.2 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ETZ05528.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Lactamase_B PF00753.27 ETZ05529.1 - 1e-12 48.5 0.0 1.3e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETZ05529.1 - 4e-06 26.5 0.0 5.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DDE_Tnp_1 PF01609.21 ETZ05531.1 - 5.7e-05 22.9 0.0 7.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_2 PF04693.12 ETZ05531.1 - 0.095 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 Mito_fiss_reg PF05308.11 ETZ05532.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial fission regulator FlaC_arch PF05377.11 ETZ05532.1 - 2.9 8.3 12.3 0.16 12.4 2.8 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) RNA_GG_bind PF10258.9 ETZ05533.1 - 0.063 13.3 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 PHAX RNA-binding domain Y_phosphatase PF00102.27 ETZ05535.1 - 0.062 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LZ3wCH PF18517.1 ETZ05535.1 - 4.9 7.3 6.7 8 6.6 0.5 3.0 3 0 0 3 3 3 0 Leucine zipper with capping helix domain CPSase_L_D2 PF02786.17 ETZ05537.1 - 1.3e-69 233.9 0.0 1.8e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETZ05537.1 - 8.3e-45 151.9 0.2 2.1e-44 150.6 0.2 1.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETZ05537.1 - 7.6e-37 125.7 0.0 2.9e-36 123.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 ETZ05537.1 - 2.1e-09 37.2 0.0 4.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ETZ05537.1 - 9.3e-07 28.6 0.0 2.9e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ETZ05537.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 ETZ05537.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 ETZ05537.1 - 0.033 13.4 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp CENP-M PF11111.8 ETZ05537.1 - 0.04 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) GARS_A PF01071.19 ETZ05537.1 - 0.096 12.4 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DNA_pol_A PF00476.20 ETZ05538.1 - 2.9e-124 415.0 0.0 4.5e-124 414.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 ETZ05538.1 - 1.5e-38 132.2 0.0 2.7e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 ETZ05538.1 - 2e-20 73.2 0.1 1.1e-19 70.8 0.0 2.4 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 ETZ05538.1 - 0.057 14.0 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain SIS PF01380.22 ETZ05540.1 - 2.1e-45 153.8 0.0 2.9e-23 82.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ETZ05540.1 - 4.9e-24 85.0 0.0 1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ETZ05540.1 - 3.4e-18 65.7 0.0 9.5e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETZ05540.1 - 0.0082 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_4 PF13230.6 ETZ05540.1 - 0.024 13.5 0.1 0.04 12.8 0.1 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II GATase_2 PF00310.21 ETZ05540.1 - 0.12 11.0 0.4 0.75 8.4 0.2 2.1 2 1 0 2 2 2 0 Glutamine amidotransferases class-II Myelin_MBP PF01669.17 ETZ05540.1 - 0.2 12.3 0.0 0.4 11.3 0.0 1.4 1 0 0 1 1 1 0 Myelin basic protein HhH-GPD PF00730.25 ETZ05541.1 - 9.4e-19 67.9 0.0 1.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 ETZ05541.1 - 3.4e-13 49.5 0.0 6.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain EndIII_4Fe-2S PF10576.9 ETZ05541.1 - 0.0053 17.1 6.3 0.0092 16.3 6.3 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.23 ETZ05541.1 - 0.047 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif DDE_3 PF13358.6 ETZ05542.1 - 1.3e-16 60.6 0.3 1.5e-16 60.5 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 ETZ05543.1 - 0.00029 20.6 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 ETZ05549.1 - 0.022 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix PSII_Pbs27 PF13326.6 ETZ05552.1 - 0.0039 17.5 1.9 0.011 16.0 1.9 2.1 1 1 0 1 1 1 1 Photosystem II Pbs27 KIP1 PF07765.12 ETZ05552.1 - 1.6 8.9 14.2 0.6 10.3 0.9 4.3 4 1 1 5 5 5 0 KIP1-like protein PHM7_cyt PF14703.6 ETZ05552.1 - 1.6 8.9 16.6 0.045 14.0 7.4 2.5 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Bcr-Abl_Oligo PF09036.10 ETZ05552.1 - 1.9 8.6 6.5 1.7 8.7 1.1 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PseudoU_synth_2 PF00849.22 ETZ05553.1 - 7.9e-13 48.8 0.0 4.4e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ETZ05553.1 - 0.00024 20.7 0.1 0.00049 19.8 0.1 1.5 1 0 0 1 1 1 1 S4 domain CBS PF00571.28 ETZ05554.1 - 1.7e-12 47.6 0.5 6.8e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain SIS PF01380.22 ETZ05554.1 - 1.4e-11 44.3 0.1 2.9e-11 43.3 0.0 1.5 2 0 0 2 2 2 1 SIS domain DUF1493 PF07377.12 ETZ05555.1 - 0.034 14.6 0.5 0.92 10.0 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1493) ASXH PF13919.6 ETZ05555.1 - 0.089 12.8 0.9 0.089 12.8 0.9 1.8 2 1 0 2 2 2 0 Asx homology domain zf-CCCH_7 PF18586.1 ETZ05555.1 - 0.092 13.1 3.1 0.23 11.8 0.4 2.4 2 1 1 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Gly-zipper_Omp PF13488.6 ETZ05556.1 - 3.9e-06 26.8 21.1 6.9e-06 26.0 21.1 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 ETZ05556.1 - 4e-05 23.3 19.0 7.5e-05 22.4 19.0 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 ETZ05556.1 - 5.3e-05 23.0 21.8 8.4e-05 22.4 21.8 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 ETZ05556.1 - 0.065 13.0 22.7 0.066 13.0 21.3 1.7 1 1 1 2 2 2 0 Glycine-zipper domain TraT PF05818.12 ETZ05556.1 - 0.11 12.2 4.7 0.14 11.8 4.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.9 ETZ05556.1 - 0.27 11.4 11.7 0.59 10.3 11.7 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_undulata_HU1-ASM38817v3/GCA_000388175.3_ASM38817v3_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_undulata_HU1-ASM38817v3/GCA_000388175.3_ASM38817v3_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_undulata_HU1-ASM38817v3/GCA_000388175.3_ASM38817v3_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_undulata_HU1-ASM38817v3/GCA_000388175.3_ASM38817v3_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:34:02 2019 # [ok]