# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SBF PF01758.16 EON30276.1 - 1.2e-25 90.4 1.4 1.3e-25 90.3 1.4 1.0 1 0 0 1 1 1 1 Sodium Bile acid symporter family NTP_transferase PF00483.23 EON30277.1 - 3e-11 43.4 0.2 3.1e-11 43.3 0.2 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON30277.1 - 0.00011 22.6 0.0 0.00011 22.6 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EON30279.1 - 1.9e-11 44.0 0.2 1.9e-11 44.0 0.2 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON30279.1 - 0.00016 22.1 0.0 0.00016 22.0 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EON30280.1 - 1.2e-20 74.1 0.0 1.3e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON30280.1 - 1.3e-05 25.6 0.0 1.4e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain SBF PF01758.16 EON30282.1 - 7.3e-11 42.1 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family Transposase_mut PF00872.18 EON30283.1 - 9.7e-29 100.4 0.0 1.1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family rve_3 PF13683.6 EON30284.1 - 1.2e-05 25.0 0.0 1.3e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EON30284.1 - 0.007 16.5 0.0 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_1 PF01527.20 EON30285.1 - 1.2e-15 57.5 1.0 1.7e-15 57.1 1.0 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EON30285.1 - 2.1e-05 24.1 0.1 5.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EON30285.1 - 6.8e-05 22.2 0.0 0.00023 20.5 0.0 1.8 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 EON30285.1 - 6.9e-05 22.9 0.1 0.00022 21.3 0.1 1.9 1 1 1 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EON30285.1 - 9e-05 22.9 0.2 0.00011 22.6 0.2 1.5 1 1 0 1 1 1 1 leucine-zipper of insertion element IS481 Sigma70_r4_2 PF08281.12 EON30285.1 - 0.00022 20.8 0.0 0.0005 19.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HA PF03457.14 EON30285.1 - 0.0029 17.9 0.1 0.0046 17.2 0.1 1.5 1 1 0 1 1 1 1 Helicase associated domain HTH_29 PF13551.6 EON30285.1 - 0.0033 17.4 0.1 0.0072 16.3 0.1 1.7 1 1 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 EON30285.1 - 0.032 14.1 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF746 PF05344.11 EON30285.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Phage_terminase PF10668.9 EON30285.1 - 0.071 13.1 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit HTH_Tnp_IS630 PF01710.16 EON30285.1 - 0.083 12.9 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Transposase NUDE_C PF04880.13 EON30285.1 - 0.12 12.9 0.8 0.17 12.4 0.8 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Transposase_mut PF00872.18 EON30286.1 - 3.3e-27 95.3 0.0 3.6e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family HTH_Tnp_Tc3_2 PF01498.18 EON30286.1 - 0.046 14.0 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.6 EON30286.1 - 0.092 13.4 0.1 0.15 12.7 0.0 1.6 1 1 0 1 1 1 0 Homeodomain-like domain rve_3 PF13683.6 EON30287.1 - 1.9e-14 53.2 0.0 2.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 EON30287.1 - 7.6e-13 48.7 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EON30287.1 - 3.7e-09 36.6 0.1 5.1e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EON30287.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.0 1 0 0 1 1 1 0 DDE domain NTP_transferase PF00483.23 EON30288.1 - 8.5e-25 87.8 0.0 9.5e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase Transposase_mut PF00872.18 EON30289.1 - 8.7e-08 31.4 0.1 1.1e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Transposase, Mutator family HTH_23 PF13384.6 EON30290.1 - 2.7e-08 33.3 0.1 5.9e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 EON30290.1 - 1.5e-06 27.8 0.2 2.6e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EON30290.1 - 2.2e-05 24.4 0.6 3.1e-05 23.9 0.1 1.5 2 0 0 2 2 1 1 Winged helix-turn helix HTH_8 PF02954.19 EON30290.1 - 4.3e-05 23.2 0.3 4.3e-05 23.2 0.3 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Terminase_5 PF06056.12 EON30290.1 - 5.9e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_11 PF08279.12 EON30290.1 - 6e-05 22.9 0.0 0.00017 21.5 0.0 1.7 2 0 0 2 2 2 1 HTH domain HTH_28 PF13518.6 EON30290.1 - 0.0002 21.4 0.2 0.0002 21.4 0.2 1.5 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_35 PF13693.6 EON30290.1 - 0.00048 20.1 0.1 0.00099 19.1 0.0 1.5 2 0 0 2 2 1 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 EON30290.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix NUMOD1 PF07453.13 EON30290.1 - 0.0015 18.7 0.2 0.0026 18.0 0.2 1.4 1 0 0 1 1 1 1 NUMOD1 domain HTH_7 PF02796.15 EON30290.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_19 PF12844.7 EON30290.1 - 0.0024 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 EON30290.1 - 0.0034 17.6 0.1 0.91 9.8 0.0 2.2 2 0 0 2 2 2 1 Transposase Sigma70_r4_2 PF08281.12 EON30290.1 - 0.0038 16.9 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_36 PF13730.6 EON30290.1 - 0.0038 17.1 0.1 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Phage_NinH PF06322.11 EON30290.1 - 0.0046 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Phage NinH protein HTH_Tnp_ISL3 PF13542.6 EON30290.1 - 0.011 15.2 0.5 0.023 14.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MDMPI_N PF11716.8 EON30290.1 - 0.011 16.4 0.2 0.013 16.2 0.2 1.2 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain HTH_17 PF12728.7 EON30290.1 - 0.012 15.8 0.1 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MerR_1 PF13411.6 EON30290.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_40 PF14493.6 EON30290.1 - 0.02 15.3 0.0 0.024 15.1 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 EON30290.1 - 0.039 14.3 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 EON30290.1 - 0.04 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein HTH_AraC PF00165.23 EON30290.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family zf-dskA_traR PF01258.17 EON30290.1 - 0.071 13.1 0.5 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger YdaS_antitoxin PF15943.5 EON30290.1 - 0.08 12.8 0.1 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_IclR PF09339.10 EON30290.1 - 0.091 12.6 0.0 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 EON30290.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.19 EON30290.1 - 0.2 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family AMP-binding PF00501.28 EON30291.1 - 1.2e-14 53.8 0.4 1.3e-14 53.6 0.4 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ESX-1_EspG PF14011.6 EON30291.1 - 0.0036 16.9 8.1 0.0043 16.7 8.1 1.0 1 0 0 1 1 1 1 EspG family HTH_24 PF13412.6 EON30291.1 - 0.054 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EON30291.1 - 0.15 11.9 0.5 0.3 11.0 0.5 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Transposase_mut PF00872.18 EON30294.1 - 2.5e-46 158.3 0.0 2.7e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family HTH_Tnp_Tc3_2 PF01498.18 EON30294.1 - 0.074 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.6 EON30294.1 - 0.14 12.8 0.1 0.26 11.9 0.1 1.8 1 1 0 1 1 1 0 Homeodomain-like domain Transposase_mut PF00872.18 EON30295.1 - 1.2e-20 73.8 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DUF222 PF02720.17 EON30296.1 - 1.2e-21 77.5 0.2 1.3e-21 77.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) ABC_tran PF00005.27 EON30297.1 - 3.9e-30 105.2 0.0 4.4e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON30297.1 - 3.6e-06 27.0 0.2 0.064 13.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON30297.1 - 0.0018 17.9 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON30297.1 - 0.0058 16.6 0.2 0.0093 15.9 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EON30297.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON30297.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EON30297.1 - 0.018 15.5 0.0 0.082 13.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON30297.1 - 0.022 15.0 0.1 0.031 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EON30297.1 - 0.033 13.1 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Mg_chelatase PF01078.21 EON30297.1 - 0.033 13.6 0.0 0.08 12.3 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EON30297.1 - 0.035 13.8 0.1 0.059 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON30297.1 - 0.07 13.5 0.1 0.08 13.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EON30297.1 - 0.079 12.9 0.3 0.36 10.7 0.1 1.9 1 1 1 2 2 2 0 NACHT domain IIGP PF05049.13 EON30297.1 - 0.086 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 EON30297.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EON30297.1 - 0.15 11.4 0.1 0.29 10.5 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PPV_E1_C PF00519.17 EON30297.1 - 0.31 9.8 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DDE_Tnp_1_4 PF13701.6 EON30299.1 - 1.7e-25 89.2 0.2 1.9e-25 89.1 0.2 1.0 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 EON30299.1 - 0.00024 20.8 0.1 0.00031 20.5 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_1 PF01527.20 EON30300.1 - 0.0017 18.6 1.2 0.0026 18.0 1.2 1.5 1 1 0 1 1 1 1 Transposase Phage_terminase PF10668.9 EON30300.1 - 0.0037 17.2 0.0 0.0071 16.3 0.0 1.6 1 1 0 1 1 1 1 Phage terminase small subunit HTH_32 PF13565.6 EON30300.1 - 0.011 16.3 0.1 0.033 14.8 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain SIKE PF05769.11 EON30300.1 - 0.015 15.2 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 SIKE family HTH_Tnp_ISL3 PF13542.6 EON30300.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EON30300.1 - 0.081 12.7 0.4 0.25 11.2 0.4 1.9 1 1 0 1 1 1 0 Homeodomain-like domain DivIC PF04977.15 EON30300.1 - 0.3 10.9 2.4 0.36 10.6 1.8 1.6 1 1 0 1 1 1 0 Septum formation initiator rve PF00665.26 EON30302.1 - 3.4e-24 85.3 0.2 4.6e-24 84.9 0.2 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EON30302.1 - 2.3e-17 62.5 0.0 3.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EON30302.1 - 1.5e-06 28.3 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EON30302.1 - 0.00016 22.0 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 DDE domain Fer2_4 PF13510.6 EON30303.1 - 0.01 15.9 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain BtrH_N PF14399.6 EON30304.1 - 1.2e-37 129.2 0.0 1.5e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal DUF4872 PF16169.5 EON30304.1 - 1.7e-12 47.5 0.2 2.4e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4872) Peptidase_C39_2 PF13529.6 EON30304.1 - 8.8e-05 23.1 0.0 0.00013 22.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family dTDP_sugar_isom PF00908.17 EON30306.1 - 4.4e-55 185.9 0.0 4.9e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase rve PF00665.26 EON30307.1 - 1.5e-13 51.0 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 EON30307.1 - 0.015 15.4 2.4 0.027 14.6 1.2 2.1 2 1 0 2 2 2 0 HTH-like domain HTH_32 PF13565.6 EON30307.1 - 0.16 12.6 2.5 0.16 12.6 0.3 2.0 2 0 0 2 2 2 0 Homeodomain-like domain GDP_Man_Dehyd PF16363.5 EON30309.1 - 1.4e-74 251.5 0.0 1.8e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EON30309.1 - 5e-59 199.7 0.0 5.8e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON30309.1 - 2e-16 59.8 0.0 2.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EON30309.1 - 3.9e-13 49.2 0.2 5.2e-12 45.5 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EON30309.1 - 3.3e-10 39.5 0.1 4.3e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EON30309.1 - 5e-09 35.7 0.0 1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EON30309.1 - 7.1e-06 26.0 0.1 1.4e-05 25.1 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EON30309.1 - 0.051 13.1 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 EON30309.1 - 0.09 12.2 0.1 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase IBV_3C PF03620.13 EON30310.1 - 0.22 12.0 0.0 3.2 8.3 0.0 2.0 2 0 0 2 2 2 0 IBV 3C protein DUF222 PF02720.17 EON30312.1 - 3.3e-25 89.2 21.5 3.7e-23 82.5 21.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF222) Asparaginase_II PF06089.12 EON30312.1 - 0.021 13.9 2.3 0.068 12.2 0.5 2.1 2 0 0 2 2 2 0 L-asparaginase II rve PF00665.26 EON30313.1 - 1.2e-31 109.3 0.1 2.1e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EON30313.1 - 4e-18 64.9 2.4 4e-18 64.9 2.4 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.6 EON30313.1 - 0.00029 21.4 3.6 0.00029 21.4 3.6 3.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 EON30313.1 - 0.0022 17.7 3.1 0.0048 16.7 2.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 EON30313.1 - 0.0072 16.1 0.6 0.014 15.2 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 EON30313.1 - 0.0092 15.9 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 EON30313.1 - 0.012 15.6 0.5 0.039 14.0 0.5 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 EON30313.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EON30313.1 - 0.025 15.1 7.1 0.24 12.0 1.8 2.8 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 Transposase_20 PF02371.16 EON30314.1 - 3.8e-18 65.6 0.3 8.1e-18 64.5 0.3 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 EON30314.1 - 1.3e-10 41.4 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Transposase rve PF00665.26 EON30315.1 - 2.7e-32 111.4 0.3 4.7e-32 110.7 0.0 1.6 2 0 0 2 2 1 1 Integrase core domain rve_3 PF13683.6 EON30315.1 - 1.7e-18 66.1 1.7 1.7e-18 66.1 1.7 2.0 2 0 0 2 2 2 1 Integrase core domain LZ_Tnp_IS481 PF13011.6 EON30315.1 - 2.1e-17 63.4 8.9 2.8e-17 63.0 4.1 2.6 1 1 1 2 2 2 1 leucine-zipper of insertion element IS481 HTH_23 PF13384.6 EON30315.1 - 8.2e-13 47.7 7.6 1.2e-08 34.4 0.5 2.9 3 0 0 3 3 2 2 Homeodomain-like domain HTH_32 PF13565.6 EON30315.1 - 2.9e-11 43.8 5.0 2.9e-11 43.8 5.0 3.6 4 1 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 EON30315.1 - 5.6e-11 42.4 9.7 4.8e-10 39.4 1.9 3.0 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_29 PF13551.6 EON30315.1 - 7.8e-10 38.6 13.2 2.6e-08 33.8 0.7 2.8 3 0 0 3 3 2 2 Winged helix-turn helix Terminase_5 PF06056.12 EON30315.1 - 7.5e-07 29.0 0.2 0.024 14.5 0.0 2.5 2 0 0 2 2 2 2 Putative ATPase subunit of terminase (gpP-like) HTH_38 PF13936.6 EON30315.1 - 8.3e-06 25.5 2.3 0.0023 17.6 0.3 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EON30315.1 - 0.00038 19.8 0.4 0.93 9.0 0.3 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 EON30315.1 - 0.00052 19.8 0.1 0.0057 16.4 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 EON30315.1 - 0.0017 18.0 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 2 Sigma-70, region 4 DDE_Tnp_IS240 PF13610.6 EON30315.1 - 0.0035 17.6 0.1 0.0055 16.9 0.1 1.3 1 0 0 1 1 1 1 DDE domain HTH_17 PF12728.7 EON30315.1 - 0.0081 16.3 0.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 EON30315.1 - 0.013 15.2 0.1 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_1 PF00126.27 EON30315.1 - 0.016 15.2 0.0 0.092 12.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_1 PF01527.20 EON30315.1 - 0.059 13.7 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Transposase HTH_50 PF18024.1 EON30315.1 - 0.16 11.6 0.2 16 5.2 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain AMP-binding PF00501.28 EON30316.1 - 3.7e-60 203.7 0.4 4.1e-60 203.6 0.4 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DDE_Tnp_1_4 PF13701.6 EON30317.1 - 3.2e-49 167.4 0.0 4.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 EON30317.1 - 0.00041 20.1 0.1 0.00063 19.4 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_4 PF13701.6 EON30318.1 - 3e-13 48.8 0.0 4.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 EON30318.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain HTH_18 PF12833.7 EON30319.1 - 7.7e-18 64.6 0.0 9.9e-17 61.0 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON30319.1 - 1.3e-10 41.1 0.0 8.8e-07 28.9 0.0 2.8 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Arabinose_bd PF12625.7 EON30319.1 - 2e-09 37.8 0.3 2e-09 37.8 0.3 2.0 2 1 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_7 PF02796.15 EON30319.1 - 0.0003 20.8 0.0 0.21 11.7 0.0 2.7 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 EON30319.1 - 0.00073 19.2 0.1 3.4 7.5 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 EON30319.1 - 0.00079 19.2 1.0 0.42 10.5 0.2 3.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 EON30319.1 - 0.017 14.9 0.1 0.089 12.6 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain HTH_11 PF08279.12 EON30319.1 - 0.032 14.2 0.2 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 HTH domain SurA_N PF09312.11 EON30319.1 - 0.042 13.9 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain HTH_20 PF12840.7 EON30319.1 - 0.057 13.5 0.0 1.1 9.4 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 EON30319.1 - 0.1 12.8 1.7 52 4.1 0.1 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 EON30319.1 - 0.12 12.4 0.1 29 4.8 0.0 3.2 2 1 1 3 3 3 0 Winged helix-turn helix HTH_5 PF01022.20 EON30319.1 - 0.18 11.7 0.2 0.56 10.1 0.2 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family rve PF00665.26 EON30320.1 - 1.2e-10 41.6 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain FA_desaturase PF00487.24 EON30321.1 - 1.4e-27 97.1 2.7 1.9e-27 96.7 2.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Phasin PF05597.11 EON30322.1 - 0.12 12.4 0.4 4.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF772 PF05598.11 EON30323.1 - 2.7e-16 59.4 0.0 4.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 EON30323.1 - 0.0086 15.7 0.2 0.028 14.1 0.0 1.9 3 0 0 3 3 3 1 Transposase DDE domain Sacchrp_dh_NADP PF03435.18 EON30323.1 - 0.32 11.2 1.7 0.57 10.5 0.6 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DEDD_Tnp_IS110 PF01548.17 EON30324.1 - 1.8e-35 122.1 0.2 4e-35 121.0 0.2 1.6 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 EON30324.1 - 2.8e-12 46.8 0.2 2.8e-12 46.8 0.2 2.1 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DDE_Tnp_1 PF01609.21 EON30325.1 - 1.2e-15 57.8 0.0 5.1e-15 55.7 0.0 2.1 2 1 0 2 2 2 1 Transposase DDE domain HTH_38 PF13936.6 EON30326.1 - 1.3e-19 69.7 1.7 2.9e-19 68.6 1.5 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON30326.1 - 6e-06 25.9 6.2 0.002 17.9 1.0 3.7 3 1 1 4 4 4 2 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EON30326.1 - 2.4e-05 23.9 0.1 0.00039 20.0 0.3 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 MarR_2 PF12802.7 EON30326.1 - 0.023 14.6 0.2 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 EON30326.1 - 0.037 14.1 0.6 0.037 14.1 0.6 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 EON30326.1 - 0.039 14.0 6.1 0.17 11.9 0.2 3.7 4 1 1 5 5 5 0 Winged helix-turn helix DUF746 PF05344.11 EON30326.1 - 0.049 13.5 0.0 5.6 6.9 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_Tnp_Tc3_1 PF11427.8 EON30326.1 - 0.075 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Tc3 transposase HTH_32 PF13565.6 EON30326.1 - 0.48 11.1 16.4 1.8 9.3 0.2 3.4 1 1 1 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.6 EON30326.1 - 0.76 10.2 5.7 5.8 7.3 0.3 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain Mrr_cat PF04471.12 EON30327.1 - 0.0054 16.7 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Condensation PF00668.20 EON30328.1 - 5.2e-80 269.3 0.0 7.3e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EON30328.1 - 4.4e-17 62.2 0.1 3.2e-16 59.4 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON30328.1 - 1.3e-10 42.1 1.1 5.7e-10 40.0 1.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hypoth_Ymh PF09509.10 EON30330.1 - 4.3e-25 87.9 0.0 6.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (Hypoth_ymh) Epimerase PF01370.21 EON30333.1 - 5.4e-53 179.9 0.0 6.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON30333.1 - 1.5e-52 179.1 0.0 1.8e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EON30333.1 - 2.8e-14 52.9 0.0 8.2e-14 51.4 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EON30333.1 - 1.7e-12 47.0 0.0 3.5e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EON30333.1 - 7.6e-11 41.7 0.0 4e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EON30333.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EON30333.1 - 4.8e-05 22.9 0.0 8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON30333.1 - 6.4e-05 22.9 0.1 0.00012 22.0 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EON30333.1 - 0.00049 19.4 0.0 0.0029 16.8 0.0 2.0 1 1 0 2 2 2 1 Male sterility protein UDPG_MGDP_dh_N PF03721.14 EON30333.1 - 0.0065 16.1 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EON30333.1 - 0.06 12.9 0.4 1.5 8.3 0.7 2.3 2 1 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 EON30333.1 - 0.16 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 EON30333.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Lactamase_B PF00753.27 EON30334.1 - 0.0029 17.6 0.4 0.0043 17.1 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Acetyltransf_CG PF14542.6 EON30335.1 - 2.5e-18 65.9 0.0 3.1e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 EON30335.1 - 8.7e-05 22.7 0.0 9.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON30335.1 - 0.011 15.6 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON30335.1 - 0.046 13.8 0.1 0.06 13.4 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON30335.1 - 0.048 14.3 0.0 0.059 14.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON30335.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ThiC_Rad_SAM PF01964.18 EON30336.1 - 5.9e-199 661.1 0.0 7.4e-199 660.8 0.0 1.1 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 EON30336.1 - 2.4e-14 52.9 0.1 8.4e-14 51.2 0.1 2.0 1 0 0 1 1 1 1 ThiC-associated domain Nuc_recep-AF1 PF11825.8 EON30336.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 IstB_IS21 PF01695.17 EON30337.1 - 2e-39 135.2 1.0 2.8e-39 134.7 1.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EON30337.1 - 6.1e-12 45.8 0.0 9.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein AFG1_ATPase PF03969.16 EON30337.1 - 2.4e-07 30.0 0.1 2.9e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA PF00004.29 EON30337.1 - 0.0015 18.9 0.1 0.003 18.0 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EON30337.1 - 0.0033 17.8 2.8 0.0034 17.8 0.3 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EON30337.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EON30337.1 - 0.0079 15.8 1.8 0.11 12.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EON30337.1 - 0.011 15.7 0.1 0.028 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EON30337.1 - 0.029 14.6 3.9 0.099 12.9 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 EON30337.1 - 0.039 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON30337.1 - 0.04 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EON30337.1 - 0.044 14.3 0.1 0.13 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON30337.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EON30337.1 - 0.12 11.7 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EON30337.1 - 0.16 11.5 0.1 0.57 9.7 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EON30337.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EON30337.1 - 0.21 12.0 0.0 0.72 10.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Transposase_mut PF00872.18 EON30339.1 - 2.2e-57 194.7 0.0 2.6e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 EON30339.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 MULE transposase domain DUF4872 PF16169.5 EON30340.1 - 9e-26 90.7 1.5 1e-25 90.5 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4872) IstB_IS21 PF01695.17 EON30341.1 - 8.1e-12 45.2 0.2 9.5e-12 45.0 0.2 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein hemP PF10636.9 EON30341.1 - 0.042 13.6 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Hemin uptake protein hemP IstB_IS21 PF01695.17 EON30342.1 - 5.7e-33 114.1 0.0 8.1e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 EON30342.1 - 1.1e-06 28.6 0.9 1.4e-06 28.2 0.2 1.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EON30342.1 - 1.2e-05 25.7 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON30342.1 - 5.2e-05 23.3 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EON30342.1 - 0.00088 19.6 0.0 0.013 15.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EON30342.1 - 0.001 19.5 3.4 0.0012 19.2 0.1 2.3 1 1 2 3 3 3 1 AAA ATPase domain MCM PF00493.23 EON30342.1 - 0.0011 18.2 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain AAA_11 PF13086.6 EON30342.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON30342.1 - 0.0018 17.9 2.8 0.0033 17.0 0.5 2.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EON30342.1 - 0.0021 18.3 0.3 0.0046 17.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EON30342.1 - 0.0033 16.9 0.1 0.005 16.3 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 EON30342.1 - 0.0056 17.0 0.6 0.0098 16.2 0.2 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EON30342.1 - 0.0063 16.0 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 EON30342.1 - 0.0071 16.3 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 EON30342.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EON30342.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EON30342.1 - 0.0089 16.3 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EON30342.1 - 0.014 14.6 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CbiA PF01656.23 EON30342.1 - 0.024 14.7 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EON30342.1 - 0.025 15.1 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON30342.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EON30342.1 - 0.042 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EON30342.1 - 0.044 13.5 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.22 EON30342.1 - 0.045 13.4 0.2 0.075 12.6 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 EON30342.1 - 0.065 12.4 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EON30342.1 - 0.071 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC Sigma54_activ_2 PF14532.6 EON30342.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EON30342.1 - 0.19 12.2 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 EON30342.1 - 0.2 11.7 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KTI12 PF08433.10 EON30342.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EON30342.1 - 0.22 11.4 0.0 3.4 7.6 0.0 2.1 2 0 0 2 2 2 0 NTPase rve PF00665.26 EON30343.1 - 0.00035 20.8 0.1 0.00088 19.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DUF3236 PF11576.8 EON30343.1 - 0.2 11.3 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) malic PF00390.19 EON30346.1 - 7.8e-27 94.2 0.0 1.8e-24 86.6 0.0 2.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EON30346.1 - 2.6e-19 69.5 4.1 4.6e-18 65.4 4.1 2.6 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 EON30346.1 - 0.00015 21.5 0.9 0.00026 20.8 0.9 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox_3 PF13738.6 EON30346.1 - 0.0041 16.4 3.0 0.0066 15.7 1.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON30346.1 - 0.011 15.1 0.2 0.062 12.7 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON30346.1 - 0.1 11.8 1.2 0.17 11.1 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 EON30346.1 - 0.12 11.7 3.5 0.22 10.9 3.5 1.3 1 0 0 1 1 1 0 ThiF family FCD PF07729.12 EON30347.1 - 4.5e-18 65.9 14.1 8.2e-18 65.0 14.1 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON30347.1 - 2.2e-15 56.0 0.2 4.4e-15 55.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EON30347.1 - 0.013 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EON30347.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 EON30347.1 - 0.21 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 EON30348.1 - 1.8e-23 83.1 41.4 1.8e-23 83.1 41.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON30348.1 - 2.8e-11 43.0 4.9 2.8e-11 43.0 4.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EON30348.1 - 3.1 6.6 13.2 0.06 12.2 1.1 2.3 2 1 0 2 2 2 0 MFS_1 like family Trp_oprn_chp PF09534.10 EON30349.1 - 0.01 15.6 5.3 0.01 15.6 5.3 5.8 4 2 1 5 5 5 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TraQ PF09679.10 EON30349.1 - 4.1 7.4 7.0 4.4 7.3 2.0 3.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) AAA_22 PF13401.6 EON30352.1 - 2.2e-15 57.1 0.0 6.6e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EON30352.1 - 1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein DnaB_C PF03796.15 EON30352.1 - 0.001 18.4 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.29 EON30352.1 - 0.012 16.0 0.0 0.028 14.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EON30352.1 - 0.044 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EON30352.1 - 0.089 13.2 1.0 1.3 9.4 0.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain rve PF00665.26 EON30353.1 - 1.2e-11 44.9 0.0 4e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 EON30353.1 - 2.4e-07 30.8 0.7 3.6e-06 27.0 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 EON30353.1 - 7.8e-07 28.7 1.1 1.1e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 EON30353.1 - 5.7e-06 26.3 5.1 6.9e-06 26.0 0.0 3.6 5 0 0 5 5 5 1 Winged helix-turn helix HTH_32 PF13565.6 EON30353.1 - 0.00011 22.8 1.4 0.00021 21.8 0.2 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Mu-transpos_C PF09299.11 EON30353.1 - 0.0056 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Mu transposase, C-terminal HTH_Tnp_ISL3 PF13542.6 EON30353.1 - 0.024 14.1 0.1 0.078 12.4 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Creatinase_N PF01321.18 EON30354.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.6 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain HSDR_N_2 PF13588.6 EON30354.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Lon_C PF05362.13 EON30355.1 - 4.7e-86 287.6 0.8 8.3e-86 286.8 0.8 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EON30355.1 - 1.2e-20 74.2 0.0 3.5e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 EON30355.1 - 2.1e-15 57.2 0.0 3.2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EON30355.1 - 6.5e-10 38.9 0.1 1.1e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EON30355.1 - 3e-08 33.8 0.0 6.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EON30355.1 - 1.7e-05 25.0 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EON30355.1 - 0.00018 21.9 0.7 0.00018 21.9 0.7 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EON30355.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON30355.1 - 0.0031 17.8 0.2 0.14 12.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 EON30355.1 - 0.0039 16.1 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_33 PF13671.6 EON30355.1 - 0.0064 16.7 0.5 0.022 14.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EON30355.1 - 0.0065 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON30355.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EON30355.1 - 0.027 14.4 0.1 0.11 12.3 0.1 2.2 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.6 EON30355.1 - 0.046 13.3 1.5 0.11 12.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EON30355.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EON30355.1 - 0.088 12.5 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EON30355.1 - 0.096 11.9 0.1 0.22 10.7 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EON30355.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain GGDEF_2 PF17853.1 EON30355.1 - 0.23 11.7 2.3 1.2 9.4 0.3 3.1 3 0 0 3 3 3 0 GGDEF-like domain HNH PF01844.23 EON30356.1 - 0.011 15.9 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease DDE_Tnp_1_4 PF13701.6 EON30357.1 - 6e-31 107.2 0.0 8.1e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 EON30357.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Transposase DDE domain Methyltransf_25 PF13649.6 EON30358.1 - 1.9e-20 73.3 0.0 3.7e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON30358.1 - 5.1e-20 71.9 0.1 8.8e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON30358.1 - 7.8e-18 64.7 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30358.1 - 3.3e-15 56.6 0.0 5.4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON30358.1 - 4.2e-14 52.7 0.0 5.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON30358.1 - 6.1e-09 35.6 0.0 2.2e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EON30358.1 - 5e-08 32.7 0.0 7.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EON30358.1 - 4.7e-06 25.9 0.0 6.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 EON30358.1 - 6.5e-06 25.9 0.0 9.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 EON30358.1 - 4.5e-05 23.1 0.1 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PCMT PF01135.19 EON30358.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EON30358.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON30358.1 - 0.00063 19.1 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EON30358.1 - 0.00068 19.1 0.0 0.0017 17.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EON30358.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EON30358.1 - 0.044 13.7 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EON30358.1 - 0.13 11.7 0.0 11 5.5 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 EON30358.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.20 EON30358.1 - 0.27 10.3 0.0 0.36 9.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TauE PF01925.19 EON30359.1 - 7.1e-41 140.4 33.3 8.6e-41 140.1 33.3 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3754 PF12576.8 EON30359.1 - 9.9 6.1 7.1 1.4 8.9 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) DUF808 PF05661.12 EON30360.1 - 1.3e-122 408.6 11.8 1.5e-122 408.4 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) Myc_target_1 PF15179.6 EON30360.1 - 0.013 15.4 0.3 0.013 15.4 0.3 2.1 2 0 0 2 2 2 0 Myc target protein 1 SLC3A2_N PF16028.5 EON30360.1 - 8.4 6.0 5.9 0.71 9.5 0.6 1.9 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus AMP-binding PF00501.28 EON30361.1 - 7.3e-65 219.2 0.0 8.8e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30361.1 - 4.7e-22 78.7 0.1 2e-21 76.7 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PNKP_ligase PF16542.5 EON30362.1 - 5.7e-125 417.1 0.0 1.1e-124 416.1 0.0 1.4 1 0 0 1 1 1 1 PNKP adenylyltransferase domain, ligase domain PNKP-ligase_C PF16536.5 EON30362.1 - 1.1e-31 108.9 1.0 2.3e-31 107.8 1.0 1.6 1 0 0 1 1 1 1 PNKP adenylyltransferase domain, C-terminal region AAA_33 PF13671.6 EON30362.1 - 2.1e-20 73.4 0.1 4.5e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain Metallophos PF00149.28 EON30362.1 - 7.9e-10 39.6 0.0 2.1e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase KTI12 PF08433.10 EON30362.1 - 0.00049 19.6 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ATPase PF06745.13 EON30362.1 - 0.0034 16.8 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 KaiC Metallophos_2 PF12850.7 EON30362.1 - 0.0062 16.8 0.0 0.031 14.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_16 PF13191.6 EON30362.1 - 0.017 15.5 0.3 0.053 13.9 0.3 1.8 1 0 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 EON30362.1 - 0.053 13.4 3.4 0.18 11.6 0.2 2.5 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein Hen1_L PF12623.7 EON30363.1 - 1.2e-104 348.6 0.0 1.6e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 RNA repair, ligase-Pnkp-associating, region of Hen1 Methyltransf_25 PF13649.6 EON30363.1 - 2.7e-09 37.6 0.0 5.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON30363.1 - 3e-09 36.9 0.0 6.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30363.1 - 3e-08 34.3 0.0 6.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON30363.1 - 3e-06 27.1 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON30363.1 - 1.5e-05 25.5 0.0 2.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EON30363.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON30363.1 - 0.0068 15.7 0.0 0.0097 15.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Rsm22 PF09243.10 EON30363.1 - 0.0068 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 PrmA PF06325.13 EON30363.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EON30363.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 EON30363.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EON30363.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.8 EON30363.1 - 0.042 13.3 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa FtsJ PF01728.19 EON30363.1 - 0.048 13.8 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EON30363.1 - 0.054 13.5 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EON30363.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.16 EON30363.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme TetR_N PF00440.23 EON30364.1 - 5.5e-09 35.7 0.2 1.1e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON30364.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Hydrolase_4 PF12146.8 EON30365.1 - 1.5e-20 73.5 0.2 5.2e-20 71.7 0.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON30365.1 - 5e-19 69.0 0.0 1.6e-16 60.7 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON30365.1 - 5.6e-19 69.6 9.0 7.4e-19 69.2 9.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EON30365.1 - 3.1e-06 27.1 0.1 0.013 15.4 0.1 2.3 2 0 0 2 2 2 2 Serine hydrolase Peptidase_S9 PF00326.21 EON30365.1 - 8.4e-06 25.4 0.1 0.014 14.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EON30365.1 - 0.0038 16.8 0.1 5.8 6.4 0.0 2.9 2 1 1 3 3 3 2 Dienelactone hydrolase family Esterase PF00756.20 EON30365.1 - 0.0057 16.3 0.4 0.015 14.9 0.3 1.7 1 1 1 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.7 EON30365.1 - 0.0086 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.11 EON30365.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 EON30365.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EON30365.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fer2 PF00111.27 EON30366.1 - 6.2e-15 54.9 0.3 1.7e-14 53.5 0.3 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON30366.1 - 5.8e-13 49.4 0.0 1.7e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON30366.1 - 2.3e-08 34.3 0.0 3.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EON30366.1 - 0.012 15.7 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Fer2_4 PF13510.6 EON30366.1 - 0.032 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.25 EON30367.1 - 3.2e-48 163.8 0.3 4.4e-48 163.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON30367.1 - 9.2e-39 133.4 1.4 1.2e-38 133.0 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON30367.1 - 4e-14 52.9 0.2 6.8e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON30367.1 - 0.024 13.8 0.6 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EON30367.1 - 0.041 14.0 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain HHH_5 PF14520.6 EON30367.1 - 0.046 14.3 0.9 4.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain FMO-like PF00743.19 EON30368.1 - 2.7e-05 22.8 0.0 0.11 10.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like AurF PF11583.8 EON30369.1 - 1.1e-76 257.9 0.1 1.3e-76 257.6 0.1 1.0 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF DUF1413 PF07205.11 EON30369.1 - 0.063 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) PaaX PF07848.12 EON30369.1 - 0.089 13.0 0.2 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 PaaX-like protein DUF4873 PF16170.5 EON30370.1 - 3e-31 107.5 0.0 3.6e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4873) MMPL PF03176.15 EON30371.1 - 2.8e-159 529.4 39.7 5.8e-86 288.4 13.5 2.7 2 1 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 EON30371.1 - 2.5e-05 24.2 3.7 2.5e-05 24.2 3.7 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Baculo_PEP_C PF04513.12 EON30371.1 - 0.039 14.0 5.9 0.62 10.1 1.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Patched PF02460.18 EON30371.1 - 0.11 10.6 6.1 0.28 9.2 6.1 1.6 1 0 0 1 1 1 0 Patched family Hpt PF01627.23 EON30371.1 - 0.21 11.9 7.9 0.21 11.9 1.5 3.3 3 0 0 3 3 3 0 Hpt domain DUF3236 PF11576.8 EON30372.1 - 0.063 13.0 0.1 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Arr-ms PF12120.8 EON30373.1 - 1.1e-46 157.0 0.0 1.4e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Rifampin ADP-ribosyl transferase GerE PF00196.19 EON30374.1 - 4.9e-14 51.6 0.0 8.6e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON30374.1 - 2.2e-05 24.1 0.2 0.00012 21.6 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Trans_reg_C PF00486.28 EON30374.1 - 0.00079 19.5 0.1 0.002 18.2 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal AAA_16 PF13191.6 EON30374.1 - 0.0027 18.1 0.2 0.0027 18.1 0.2 3.1 3 2 0 3 3 3 1 AAA ATPase domain Sigma70_ECF PF07638.11 EON30374.1 - 0.0035 17.3 0.1 0.0066 16.4 0.1 1.4 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EON30374.1 - 0.0062 16.3 1.3 0.072 12.9 0.3 3.3 3 0 0 3 3 3 1 Homeodomain-like domain TPR_19 PF14559.6 EON30374.1 - 0.011 16.2 1.7 0.011 16.2 1.7 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 EON30374.1 - 0.017 14.6 0.5 0.043 13.3 0.5 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HSP70 PF00012.20 EON30375.1 - 9.4e-12 43.9 0.0 1.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EON30375.1 - 0.0015 17.4 1.0 0.0028 16.5 0.2 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Dynamin_N PF00350.23 EON30377.1 - 1.9e-16 60.6 0.0 1.2e-15 58.0 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EON30377.1 - 3.4e-07 30.3 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 EON30377.1 - 0.0054 15.8 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 EON30377.1 - 0.011 15.5 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EON30377.1 - 0.018 14.6 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Phyto-Amp PF15438.6 EON30377.1 - 0.12 12.2 0.1 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Antigenic membrane protein of phytoplasma AIG1 PF04548.16 EON30377.1 - 0.14 11.4 0.0 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 EON30378.1 - 3.3e-12 46.8 0.0 1.3e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EON30378.1 - 1.7e-07 31.3 0.0 3.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EON30378.1 - 0.006 16.5 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EON30378.1 - 0.017 14.6 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 EON30378.1 - 0.062 12.8 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EON30378.1 - 0.17 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 EON30378.1 - 0.21 11.0 0.0 18 4.7 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2569 PF10754.9 EON30379.1 - 0.016 15.6 2.8 0.022 15.2 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) CopD PF05425.13 EON30379.1 - 0.02 15.3 14.4 0.04 14.3 3.2 2.2 2 0 0 2 2 2 0 Copper resistance protein D Tetraspanin PF00335.20 EON30379.1 - 1.3 8.7 4.0 1.4 8.5 3.2 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 EON30379.1 - 4.9 6.8 10.4 0.09 12.4 0.8 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Cupin_2 PF07883.11 EON30380.1 - 0.0018 18.0 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 EON30380.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 ChrR Cupin-like domain LysR_substrate PF03466.20 EON30381.1 - 2.1e-31 108.9 8.3 3.7e-31 108.1 8.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EON30381.1 - 1.1e-17 63.7 0.3 3.6e-17 62.1 0.3 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EON30381.1 - 0.00046 20.0 0.5 0.0022 17.9 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EON30381.1 - 0.00052 19.5 0.2 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EON30381.1 - 0.0031 17.5 1.6 0.0074 16.3 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_30 PF13556.6 EON30381.1 - 0.012 15.4 0.0 0.063 13.1 0.1 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 EON30381.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 EON30381.1 - 0.036 14.2 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 EON30381.1 - 0.082 13.1 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Aldo_ket_red PF00248.21 EON30382.1 - 7.9e-65 218.9 0.0 9e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TetR_C_11 PF16859.5 EON30383.1 - 1.2e-22 80.4 3.8 1.2e-22 80.4 3.8 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON30383.1 - 7e-08 32.1 0.0 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Abhydrolase_6 PF12697.7 EON30384.1 - 4.9e-09 37.1 11.4 5.6e-09 36.9 11.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON30384.1 - 4.7e-05 23.2 0.1 0.0086 15.8 0.0 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EON30384.1 - 0.044 13.9 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DUF4185 PF13810.6 EON30385.1 - 1.5e-100 336.5 6.4 1.7e-100 336.3 6.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) DUF308 PF03729.13 EON30387.1 - 1.4e-18 66.9 49.3 6.6e-10 39.2 17.5 3.1 1 1 2 3 3 3 3 Short repeat of unknown function (DUF308) PGPGW PF09656.10 EON30387.1 - 0.0021 17.5 10.8 0.0021 17.5 10.8 4.1 3 1 0 3 3 3 2 Putative transmembrane protein (PGPGW) AMP-binding PF00501.28 EON30388.1 - 4.6e-70 236.3 0.4 2.9e-69 233.7 0.0 2.2 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 EON30388.1 - 3.9e-11 43.2 0.0 8.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EON30388.1 - 1.9e-05 24.2 14.8 0.0027 17.4 0.2 7.2 8 2 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 EON30388.1 - 0.0018 19.2 0.0 0.0058 17.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 EON30388.1 - 0.011 15.5 11.2 0.14 12.0 0.1 5.3 7 0 0 7 7 7 0 Hexapeptide repeat of succinyl-transferase Abhydrolase_3 PF07859.13 EON30389.1 - 7.3e-35 120.7 0.3 9.1e-35 120.4 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON30389.1 - 8e-05 21.7 0.0 0.00017 20.6 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EON30389.1 - 0.0048 16.2 0.0 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 baeRF_family10 PF18854.1 EON30389.1 - 0.083 13.1 0.7 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF202 PF02656.15 EON30390.1 - 2.7e-15 56.6 7.6 2.7e-15 56.6 7.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PKS_DE PF18369.1 EON30390.1 - 0.013 16.0 0.3 0.03 14.9 0.3 1.6 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain NMN_transporter PF04973.12 EON30390.1 - 0.017 15.1 7.5 0.084 12.8 7.6 1.8 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter Abhydrolase_9_N PF15420.6 EON30390.1 - 0.035 14.1 14.4 0.087 12.8 14.1 1.6 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus CopD PF05425.13 EON30390.1 - 0.11 12.9 16.9 0.34 11.3 16.1 1.8 1 1 1 2 2 2 0 Copper resistance protein D Oxidored_q2 PF00420.24 EON30390.1 - 0.12 12.0 4.5 0.17 11.5 4.5 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4199 PF13858.6 EON30390.1 - 0.16 12.3 2.1 0.19 12.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CrgA PF06781.12 EON30390.1 - 0.43 10.7 4.2 0.42 10.7 0.2 2.0 2 0 0 2 2 2 0 Cell division protein CrgA DUF4131 PF13567.6 EON30390.1 - 4.4 6.9 6.8 2.2 7.9 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) LapA_dom PF06305.11 EON30390.1 - 10 6.1 10.9 0.39 10.6 0.3 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PhoR PF11808.8 EON30391.1 - 0.00093 19.6 0.3 0.0011 19.3 0.3 1.1 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR DUF3043 PF11241.8 EON30391.1 - 0.021 14.8 0.1 0.022 14.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4191 PF13829.6 EON30391.1 - 0.28 10.5 2.8 0.31 10.4 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3784 PF12650.7 EON30391.1 - 1 9.6 5.5 1.3 9.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) SCIMP PF15050.6 EON30391.1 - 1.8 9.1 4.0 0.25 11.8 0.5 1.4 2 0 0 2 2 2 0 SCIMP protein TetR_N PF00440.23 EON30392.1 - 0.083 12.7 0.1 1.2 9.0 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_Tnp_1 PF01527.20 EON30393.1 - 4e-11 43.1 0.0 7.3e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 EON30393.1 - 6.9e-07 28.9 0.2 1.5e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EON30393.1 - 9.4e-06 25.7 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EON30393.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 EON30393.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_ISL3 PF13542.6 EON30393.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DivIC PF04977.15 EON30393.1 - 0.083 12.7 2.0 0.13 12.0 2.0 1.2 1 0 0 1 1 1 0 Septum formation initiator MerR_1 PF13411.6 EON30393.1 - 0.16 12.1 1.9 0.16 12.0 0.0 2.0 3 0 0 3 3 3 0 MerR HTH family regulatory protein rve PF00665.26 EON30394.1 - 8.7e-32 109.8 0.0 1.7e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 EON30394.1 - 4e-16 58.9 2.2 7.6e-16 58.0 2.2 1.5 1 0 0 1 1 1 1 HTH-like domain rve_3 PF13683.6 EON30394.1 - 2.9e-13 49.4 0.0 5.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EON30394.1 - 0.00094 19.4 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 EON30394.1 - 0.02 15.1 0.2 0.04 14.1 0.2 1.5 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 EON30395.1 - 7.5e-10 38.4 0.2 1.1e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 EON30395.1 - 2.2e-05 24.7 1.3 2.6e-05 24.4 1.3 1.3 1 1 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EON30395.1 - 3e-05 24.1 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 EON30396.1 - 0.022 14.9 0.0 0.023 14.9 0.0 1.0 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 EON30397.1 - 0.00013 22.2 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_1 PF01527.20 EON30398.1 - 1e-07 32.1 0.1 1.4e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EON30398.1 - 0.00017 21.3 1.0 0.00025 20.7 0.0 1.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EON30398.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 EON30398.1 - 0.0052 16.5 0.5 0.024 14.4 0.0 2.3 3 0 0 3 3 3 1 HTH DNA binding domain HTH_29 PF13551.6 EON30398.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 EON30398.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase MerR_1 PF13411.6 EON30398.1 - 0.035 14.2 0.0 0.056 13.6 0.0 1.5 1 1 0 1 1 1 0 MerR HTH family regulatory protein HTH_Tnp_ISL3 PF13542.6 EON30398.1 - 0.04 13.3 0.1 0.066 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 LZ_Tnp_IS481 PF13011.6 EON30398.1 - 0.046 14.2 0.2 0.066 13.8 0.2 1.4 1 1 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_AraC PF00165.23 EON30398.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_4 PF13613.6 EON30398.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MMPL PF03176.15 EON30399.1 - 1.3e-157 523.9 35.9 1.4e-86 290.5 11.4 3.0 4 0 0 4 4 4 2 MMPL family Patched PF02460.18 EON30399.1 - 0.00026 19.2 2.6 0.00026 19.2 2.6 2.0 2 0 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 EON30399.1 - 0.0013 18.5 1.9 0.0013 18.5 1.9 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SKA2 PF16740.5 EON30399.1 - 0.0027 17.5 0.8 0.0069 16.2 0.8 1.6 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 EON30399.1 - 0.0046 17.0 0.4 0.045 13.8 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EON30399.1 - 0.01 15.9 11.9 0.01 15.9 11.9 3.8 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHAD PF05235.14 EON30399.1 - 0.038 14.0 0.9 0.12 12.3 0.6 1.9 2 0 0 2 2 2 0 CHAD domain Prominin PF05478.11 EON30399.1 - 0.042 11.8 1.4 0.082 10.8 1.4 1.5 1 0 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 EON30399.1 - 0.29 11.5 6.3 3.9 7.9 2.0 2.9 2 1 0 2 2 2 0 Syntaxin-like protein TetR_N PF00440.23 EON30400.1 - 2.6e-11 43.1 0.5 4.8e-11 42.3 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EON30400.1 - 1.8e-07 31.5 2.8 1.8e-07 31.5 2.8 1.9 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 EON30400.1 - 0.05 13.6 1.9 0.23 11.4 0.1 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 EON30400.1 - 2.8 8.5 10.0 0.24 11.9 0.5 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1 PF01527.20 EON30402.1 - 1e-14 54.6 1.1 1.2e-14 54.3 1.1 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EON30402.1 - 0.0032 17.2 0.3 0.0063 16.3 0.3 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 EON30402.1 - 0.021 15.0 1.3 0.078 13.1 1.3 1.9 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_Tnp_IS630 PF01710.16 EON30402.1 - 0.077 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Transposase rve_3 PF13683.6 EON30403.1 - 1.6e-26 91.8 0.4 6.5e-25 86.7 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain rve PF00665.26 EON30403.1 - 8.4e-25 87.3 0.0 1.6e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 EON30403.1 - 3.8e-12 46.1 1.5 6.1e-12 45.5 1.5 1.3 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 EON30403.1 - 0.00041 20.5 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Transglut_core PF01841.19 EON30404.1 - 7.4e-18 65.0 0.2 1.3e-17 64.3 0.2 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pyr_redox_2 PF07992.14 EON30405.1 - 1.7e-58 198.2 7.3 2.6e-58 197.6 7.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EON30405.1 - 1.9e-28 98.8 0.8 1.4e-27 96.1 0.0 2.8 3 1 1 4 4 3 1 Reductase C-terminal Pyr_redox PF00070.27 EON30405.1 - 2.9e-17 63.0 1.4 2.2e-14 53.8 1.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON30405.1 - 9.9e-06 25.0 0.3 2.3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON30405.1 - 2.8e-05 24.3 4.1 7.3e-05 22.9 0.5 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EON30405.1 - 0.00013 21.3 0.6 0.00097 18.5 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 EON30405.1 - 0.00019 21.7 0.8 0.026 14.8 0.1 2.9 2 0 0 2 2 2 1 TrkA-N domain DAO PF01266.24 EON30405.1 - 0.00019 21.1 11.8 0.00026 20.7 1.7 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EON30405.1 - 0.00075 18.6 4.9 0.68 8.9 0.2 3.3 2 1 1 3 3 3 2 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 EON30405.1 - 0.0052 16.4 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EON30405.1 - 0.0053 17.2 1.5 0.02 15.3 1.2 2.2 1 1 1 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EON30405.1 - 0.0054 16.1 5.5 0.0054 16.1 5.5 2.5 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EON30405.1 - 0.0077 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON30405.1 - 0.011 15.7 6.2 3.9 7.5 0.2 3.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EON30405.1 - 0.012 14.3 2.8 0.027 13.2 0.2 2.4 2 1 1 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.24 EON30405.1 - 0.05 12.9 4.2 0.79 8.9 0.7 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EON30405.1 - 0.068 12.0 10.7 0.2 10.5 0.3 2.5 2 1 1 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 EON30405.1 - 0.6 9.1 5.6 1.7 7.6 0.5 3.4 3 1 1 4 4 4 0 Glucose inhibited division protein A p450 PF00067.22 EON30406.1 - 9.2e-20 70.8 0.1 8.4e-18 64.4 0.1 2.2 1 1 0 1 1 1 1 Cytochrome P450 Fer2 PF00111.27 EON30407.1 - 3.1e-13 49.5 0.4 3.8e-13 49.2 0.4 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain AMP-binding PF00501.28 EON30408.1 - 4.7e-92 308.8 0.0 5.8e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30408.1 - 1e-17 64.8 0.0 2.8e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3365 PF11845.8 EON30409.1 - 0.0022 18.3 0.5 0.003 17.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) Aminopep PF10023.9 EON30409.1 - 0.01 15.2 0.5 0.012 15.0 0.5 1.1 1 0 0 1 1 1 0 Putative aminopeptidase ABC2_membrane_3 PF12698.7 EON30409.1 - 0.056 12.6 0.7 0.064 12.3 0.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4330 PF14221.6 EON30409.1 - 0.08 13.2 1.8 0.1 12.8 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) SnoaL_3 PF13474.6 EON30409.1 - 0.093 13.0 0.1 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF2681 PF10883.8 EON30409.1 - 0.13 12.7 1.0 0.24 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) MlaD PF02470.20 EON30410.1 - 1.3e-14 54.3 0.1 3.5e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON30411.1 - 1.3e-16 60.7 0.0 2.6e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON30412.1 - 3.4e-11 43.3 0.0 6.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON30413.1 - 1.9e-12 47.3 0.7 4.5e-12 46.1 0.4 1.9 2 0 0 2 2 2 1 MlaD protein Dyp_perox PF04261.12 EON30413.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family Mce4_CUP1 PF11887.8 EON30413.1 - 0.23 10.9 2.8 0.35 10.3 1.1 1.7 1 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 EON30413.1 - 1.1 9.5 3.3 16 5.8 0.0 3.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) MlaD PF02470.20 EON30414.1 - 5e-16 58.8 0.2 9.4e-16 57.9 0.2 1.4 1 0 0 1 1 1 1 MlaD protein APG17 PF04108.12 EON30414.1 - 0.0002 20.6 0.0 0.00025 20.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1664 PF07889.12 EON30414.1 - 0.035 14.1 0.1 0.035 14.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EON30414.1 - 0.051 13.6 0.7 0.15 12.1 0.5 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Meckelin PF09773.9 EON30414.1 - 0.12 10.4 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) MlaD PF02470.20 EON30415.1 - 7.9e-08 32.5 0.3 1.6e-07 31.5 0.2 1.6 2 0 0 2 2 2 1 MlaD protein MlaE PF02405.16 EON30416.1 - 4.8e-58 196.3 20.0 7.5e-58 195.7 20.0 1.2 1 0 0 1 1 1 1 Permease MlaE FtsX PF02687.21 EON30416.1 - 0.028 14.9 3.8 0.028 14.9 3.8 2.6 2 1 0 2 2 2 0 FtsX-like permease family MlaE PF02405.16 EON30417.1 - 1.2e-26 93.7 13.6 1.4e-26 93.5 13.6 1.0 1 0 0 1 1 1 1 Permease MlaE Ninjurin PF04923.12 EON30417.1 - 0.024 14.6 1.9 0.031 14.2 1.9 1.4 1 1 0 1 1 1 0 Ninjurin Bac_export_2 PF01312.19 EON30417.1 - 0.4 9.9 4.6 0.79 8.9 4.6 1.5 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family 4HBT PF03061.22 EON30418.1 - 1.1e-06 28.8 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF772 PF05598.11 EON30419.1 - 3.2e-15 55.9 0.0 1.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 EON30419.1 - 6.6e-12 45.7 0.6 2.7e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EON30419.1 - 2.7e-08 33.7 0.1 0.00052 19.7 0.0 2.7 3 0 0 3 3 3 2 Transposase DDE domain Transposase_mut PF00872.18 EON30420.1 - 3.4e-57 194.0 0.0 3.9e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family HATPase_c_2 PF13581.6 EON30423.1 - 2.8e-18 66.1 0.0 4.9e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF664 PF04978.12 EON30423.1 - 0.033 14.6 0.5 0.22 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF664) HATPase_c PF02518.26 EON30423.1 - 0.068 13.7 0.0 0.26 11.8 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STAS_2 PF13466.6 EON30424.1 - 8.9e-09 35.6 0.5 8.9e-09 35.6 0.5 1.6 2 0 0 2 2 2 1 STAS domain STAS PF01740.21 EON30424.1 - 1.5e-08 34.3 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 STAS domain Lgl_C PF08596.10 EON30424.1 - 0.093 11.4 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal LIP PF03583.14 EON30425.1 - 9e-09 35.1 0.3 2.7e-08 33.5 0.3 1.8 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EON30425.1 - 1.9e-08 34.1 0.3 1e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EON30425.1 - 0.0018 17.6 0.1 0.0059 15.9 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EON30425.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LGFP PF08310.11 EON30427.1 - 3.7e-33 113.8 28.2 2.5e-15 56.7 5.0 4.1 4 0 0 4 4 4 4 LGFP repeat Pyr_redox_3 PF13738.6 EON30429.1 - 1.3e-18 67.3 0.0 6.2e-18 65.1 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON30429.1 - 2.1e-14 52.9 0.0 6.8e-13 47.9 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EON30429.1 - 6.2e-13 48.6 0.0 1.6e-09 37.4 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EON30429.1 - 2.9e-12 46.5 0.0 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON30429.1 - 8.5e-10 38.7 0.0 7.8e-08 32.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON30429.1 - 7.4e-07 29.6 0.0 0.029 14.9 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON30429.1 - 9.4e-07 28.3 0.0 7.4e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EON30429.1 - 1.3e-06 28.2 0.2 0.0031 17.1 0.0 4.0 3 1 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EON30429.1 - 1.7e-05 24.1 0.1 0.13 11.3 0.0 4.0 5 0 0 5 5 5 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 EON30429.1 - 0.00014 21.9 0.4 2.7 8.0 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON30429.1 - 0.00054 19.2 0.0 0.0034 16.5 0.0 2.3 4 0 0 4 4 4 1 FAD binding domain GIDA PF01134.22 EON30429.1 - 0.0066 15.6 0.0 0.36 9.8 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EON30429.1 - 0.0069 15.7 0.0 0.039 13.3 0.0 2.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EON30429.1 - 0.0095 16.0 0.0 0.39 10.8 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EON30429.1 - 0.023 15.1 0.0 0.11 12.9 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EON30429.1 - 0.042 12.5 0.0 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 EON30429.1 - 0.086 12.2 0.0 0.42 9.9 0.0 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase ApbA PF02558.16 EON30429.1 - 0.12 12.0 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.15 EON30429.1 - 0.15 10.6 0.0 1 7.8 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Molybdopterin PF00384.22 EON30430.1 - 5e-53 180.6 0.0 7.6e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EON30430.1 - 9e-23 80.4 0.1 1.9e-22 79.4 0.1 1.6 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EON30430.1 - 3.2e-09 36.6 0.0 6.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fasciclin PF02469.22 EON30431.1 - 6.8e-27 94.2 0.1 9.1e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF664 PF04978.12 EON30432.1 - 3.8e-39 134.5 4.1 4.6e-39 134.2 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 EON30432.1 - 1.1e-08 35.6 3.4 1.5e-08 35.2 3.4 1.2 1 0 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.8 EON30432.1 - 0.00022 21.9 8.1 0.00027 21.6 7.3 1.6 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.12 EON30432.1 - 0.00033 20.6 2.9 0.00068 19.6 2.9 1.4 1 1 0 1 1 1 1 DinB family TetR_C_34 PF17929.1 EON30432.1 - 0.12 12.5 0.1 0.68 10.0 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AIM24 PF01987.17 EON30433.1 - 7.5e-13 48.7 0.0 9.9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 EON30434.1 - 6.3e-26 91.4 6.9 8e-26 91.1 6.9 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 EON30435.1 - 5e-28 98.3 3.0 5.5e-28 98.1 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ArAE_2_N PF10337.9 EON30436.1 - 0.095 11.7 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CK2S PF15011.6 EON30436.1 - 0.16 11.8 5.0 0.46 10.3 2.0 2.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate IPPT PF01715.17 EON30436.1 - 1.6 8.5 4.5 2.4 7.9 2.8 2.0 1 1 1 2 2 2 0 IPP transferase C-C_Bond_Lyase PF15617.6 EON30437.1 - 1.2e-125 419.1 0.0 1.4e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold HpcH_HpaI PF03328.14 EON30437.1 - 1.7e-06 27.3 0.8 6.8e-06 25.4 0.9 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PRTase_2 PF15609.6 EON30438.1 - 8.4e-62 208.0 0.9 7.3e-61 205.0 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase TRSP PF12500.8 EON30438.1 - 1.1e-39 135.3 0.0 2.7e-39 134.1 0.0 1.7 2 0 0 2 2 2 1 TRSP domain C terminus to PRTase_2 Pribosyltran PF00156.27 EON30438.1 - 0.007 15.9 0.2 0.024 14.2 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_1 PF11202.8 EON30439.1 - 1.9e-105 351.6 0.0 2.3e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) PELOTA_1 PF15608.6 EON30439.1 - 8e-35 118.6 0.0 1.5e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 PELOTA RNA binding domain Reductase_C PF14759.6 EON30439.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Reductase C-terminal Herpes_ICP4_C PF03585.14 EON30440.1 - 0.014 14.1 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region Response_reg PF00072.24 EON30441.1 - 0.0068 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON30442.1 - 5.4e-06 25.8 0.1 8.3e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family ArfA PF03889.13 EON30442.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A Sigma70_r4_2 PF08281.12 EON30442.1 - 0.2 11.4 3.3 0.1 12.3 1.1 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON30442.1 - 0.33 10.5 4.6 0.59 9.7 4.6 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 EON30442.1 - 0.34 10.8 3.0 1.4 8.8 3.0 2.0 1 1 0 1 1 1 0 Homeodomain-like domain RhlB PF12300.8 EON30444.1 - 0.0077 16.4 1.2 0.0083 16.3 1.2 1.0 1 0 0 1 1 1 1 ATP-dependent RNA helicase RhlB LtrA PF06772.11 EON30445.1 - 1.5e-89 300.7 49.8 1.7e-89 300.5 49.8 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4271 PF14093.6 EON30445.1 - 0.078 12.9 0.0 0.078 12.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) Gemini_mov PF01708.16 EON30445.1 - 9 6.1 12.1 4.9 7.0 0.2 4.3 4 0 0 4 4 4 0 Geminivirus putative movement protein AMP-binding PF00501.28 EON30446.1 - 1.7e-71 241.1 0.2 8.1e-71 238.8 0.2 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30446.1 - 1.8e-20 73.7 0.2 1.8e-20 73.7 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MTES_1575 PF18741.1 EON30447.1 - 6.2e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 AbiEi_4 PF13338.6 EON30447.1 - 0.00082 19.5 0.4 0.0087 16.2 0.1 2.8 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin DUF559 PF04480.12 EON30447.1 - 0.00097 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) HTH_5 PF01022.20 EON30448.1 - 3.6e-17 62.0 0.0 6.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON30448.1 - 1.8e-13 50.3 0.2 3.9e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EON30448.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EON30448.1 - 0.0007 19.9 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 EON30448.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EON30448.1 - 0.014 15.3 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 EON30448.1 - 0.025 14.1 0.0 0.093 12.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 EON30448.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.6 EON30448.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain SBF PF01758.16 EON30449.1 - 7.7e-09 35.5 0.4 1.2e-08 34.9 0.0 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family Kinocilin PF15033.6 EON30449.1 - 0.0062 16.2 0.3 0.008 15.8 0.3 1.2 1 0 0 1 1 1 1 Kinocilin protein Esterase PF00756.20 EON30450.1 - 9.2e-47 159.8 0.1 1.2e-46 159.4 0.1 1.1 1 0 0 1 1 1 1 Putative esterase LGFP PF08310.11 EON30450.1 - 5.1e-16 58.9 6.8 2.7e-08 34.2 0.0 3.5 3 1 0 3 3 3 2 LGFP repeat DEC-1_N PF04625.13 EON30450.1 - 0.013 14.5 8.5 0.019 14.0 8.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_S9 PF00326.21 EON30450.1 - 0.049 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAP PF07174.11 EON30450.1 - 0.054 13.0 22.7 0.052 13.0 21.5 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DUF3357 PF11837.8 EON30450.1 - 0.19 12.2 0.9 0.38 11.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3040 PF11239.8 EON30450.1 - 0.2 11.9 0.9 0.5 10.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) JSRP PF15312.6 EON30450.1 - 3.7 7.5 7.5 0.97 9.4 3.9 1.9 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF732 PF05305.14 EON30451.1 - 1.4e-07 31.8 0.2 1.4e-07 31.8 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF732) Cutinase PF01083.22 EON30452.1 - 8.5e-15 55.2 0.0 1.4e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.13 EON30452.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 EON30452.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Bac_luciferase PF00296.20 EON30453.1 - 2.5e-55 188.1 2.8 8.5e-55 186.4 2.8 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase NAD_binding_7 PF13241.6 EON30453.1 - 0.045 14.2 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding MR_MLE_C PF13378.6 EON30453.1 - 0.084 12.4 0.3 3.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Enolase C-terminal domain-like AMP-binding PF00501.28 EON30454.1 - 2.1e-75 253.9 0.0 2.6e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EON30455.1 - 2.9e-83 279.4 0.1 6.2e-83 278.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EON30455.1 - 9.2e-49 166.6 0.0 1.6e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EON30455.1 - 7.4e-43 145.3 0.2 1.9e-42 144.0 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EON30455.1 - 2.6e-26 91.7 0.6 1.8e-12 47.4 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.20 EON30455.1 - 1.4e-21 77.7 0.0 3.3e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 EON30455.1 - 1.7e-10 41.4 0.0 3.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EON30455.1 - 9.3e-06 25.2 0.2 3.5e-05 23.3 0.2 1.9 1 1 1 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EON30455.1 - 0.00027 21.6 9.2 0.00031 21.4 0.1 4.5 4 0 0 4 4 4 1 Alpha/beta hydrolase family Carboxyl_trans PF01039.22 EON30456.1 - 3.7e-141 471.2 0.1 4.2e-141 471.0 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EON30456.1 - 6.3e-05 22.6 0.4 0.00026 20.6 0.1 1.9 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) DEDD_Tnp_IS110 PF01548.17 EON30457.1 - 3.8e-20 72.3 1.3 4.8e-20 72.0 0.2 1.7 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 EON30457.1 - 4.9e-18 65.2 0.1 1.6e-17 63.6 0.1 2.0 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family EutN_CcmL PF03319.13 EON30457.1 - 0.069 13.7 0.1 0.22 12.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutN/carboxysome TetR_C_35 PF18556.1 EON30458.1 - 3.9e-19 68.7 0.8 7.9e-19 67.7 0.8 1.5 1 0 0 1 1 1 1 Bacterial Tetracyclin repressor, C-terminal domain TetR_N PF00440.23 EON30458.1 - 2.8e-09 36.6 0.0 6e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_8 PF02954.19 EON30458.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_Tnp_1_2 PF13022.6 EON30458.1 - 0.0049 17.0 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 EON30458.1 - 0.0073 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON30458.1 - 0.036 13.9 0.1 0.088 12.6 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EON30458.1 - 0.042 13.6 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 EON30458.1 - 0.14 12.3 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GMC_oxred_C PF05199.13 EON30459.1 - 1.2e-14 55.1 0.0 2.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EON30459.1 - 2e-10 40.8 0.7 0.00021 21.0 0.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EON30459.1 - 1.8e-09 37.4 0.0 3.7e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EON30459.1 - 5.1e-08 32.4 0.2 4.5e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EON30459.1 - 1.9e-06 27.4 0.2 0.00018 20.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON30459.1 - 4.2e-05 23.7 0.6 0.00014 22.1 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EON30459.1 - 0.0029 16.7 0.1 0.33 10.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EON30459.1 - 0.0095 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Fer4_9 PF13187.6 EON30459.1 - 0.021 15.0 0.1 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain HI0933_like PF03486.14 EON30459.1 - 0.022 13.5 0.1 0.21 10.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Fer4_10 PF13237.6 EON30459.1 - 0.034 14.3 0.2 0.06 13.5 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 EON30459.1 - 0.038 14.1 0.2 0.068 13.3 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain CDKN3 PF05706.12 EON30459.1 - 0.039 13.6 0.1 0.8 9.3 0.1 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pyr_redox_3 PF13738.6 EON30459.1 - 0.057 12.7 0.0 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 EON30459.1 - 0.13 12.2 3.3 0.22 11.4 3.3 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Pyr_redox PF00070.27 EON30459.1 - 0.18 12.4 0.1 0.75 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 EON30459.1 - 0.83 9.8 3.7 1.4 9.1 3.7 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 EON30459.1 - 3.4 8.8 4.9 5.7 8.1 4.9 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain MlaE PF02405.16 EON30460.1 - 1.7e-59 201.1 20.0 2e-59 200.9 20.0 1.0 1 0 0 1 1 1 1 Permease MlaE MlaE PF02405.16 EON30461.1 - 7.7e-56 189.1 22.8 9.7e-56 188.8 22.8 1.1 1 0 0 1 1 1 1 Permease MlaE SepZ PF06066.11 EON30461.1 - 1.5 9.1 9.7 8.5 6.7 1.8 3.0 1 1 1 2 2 2 0 SepZ Phage_holin_2_4 PF16082.5 EON30461.1 - 3.6 7.4 8.7 5.9 6.7 0.1 3.2 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Mce4_CUP1 PF11887.8 EON30462.1 - 8.8e-47 159.7 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 EON30462.1 - 1.1e-10 41.7 0.0 2.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 MlaD protein DUF948 PF06103.11 EON30462.1 - 2.6 8.3 4.3 6.4 7.1 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MlaD PF02470.20 EON30463.1 - 8.6e-13 48.4 0.6 1.7e-12 47.5 0.6 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30463.1 - 0.0089 15.5 0.5 0.015 14.8 0.5 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative YajC PF02699.15 EON30463.1 - 0.11 12.4 0.3 0.23 11.3 0.3 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Baculo_PEP_C PF04513.12 EON30463.1 - 0.52 10.4 7.8 3.5 7.7 3.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MlaD PF02470.20 EON30464.1 - 3.2e-12 46.6 0.1 1.1e-11 44.8 0.1 1.9 2 0 0 2 2 2 1 MlaD protein Mce4_CUP1 PF11887.8 EON30464.1 - 2.1e-06 27.4 2.1 8.7e-05 22.1 0.2 1.8 1 1 1 2 2 2 2 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 EON30464.1 - 0.00011 22.4 2.6 0.047 14.0 0.1 3.0 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EON30464.1 - 0.0025 17.9 2.3 1.4 9.0 0.4 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 EON30464.1 - 0.013 15.8 0.0 5.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Mer2 PF09074.10 EON30464.1 - 0.031 14.1 0.2 0.097 12.5 0.2 1.8 1 1 0 1 1 1 0 Mer2 Phasin PF05597.11 EON30464.1 - 0.1 12.6 0.6 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Spc7 PF08317.11 EON30464.1 - 0.25 10.2 0.1 0.48 9.2 0.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein MlaD PF02470.20 EON30465.1 - 1.1e-12 48.0 0.1 2.4e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30465.1 - 2.9e-09 36.8 2.6 4.4e-09 36.2 2.6 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 EON30465.1 - 0.0013 18.8 2.8 1.2 9.2 0.0 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EON30465.1 - 0.034 14.6 4.7 0.23 12.0 0.6 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EON30465.1 - 0.1 12.6 0.6 1.2 9.2 0.2 2.3 1 1 2 3 3 3 0 Laminin Domain II Prefoldin PF02996.17 EON30465.1 - 0.1 12.5 0.1 0.85 9.5 0.0 2.6 2 1 1 3 3 3 0 Prefoldin subunit CortBP2 PF09727.9 EON30465.1 - 0.13 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Cortactin-binding protein-2 Flagellin_N PF00669.20 EON30465.1 - 0.18 11.9 5.0 1.3 9.1 3.5 2.3 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region COG2 PF06148.11 EON30465.1 - 0.27 11.3 0.6 4.1 7.5 0.2 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MlaD PF02470.20 EON30466.1 - 3e-10 40.3 0.8 5.2e-10 39.5 0.2 1.8 2 0 0 2 2 2 1 MlaD protein Mce4_CUP1 PF11887.8 EON30466.1 - 1.8e-09 37.4 1.5 2.8e-09 36.8 1.5 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 EON30466.1 - 0.09 12.8 3.7 1.1 9.3 1.5 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 EON30466.1 - 0.096 13.0 0.0 0.6 10.5 0.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EON30466.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MlaD PF02470.20 EON30467.1 - 6.4e-19 68.0 0.2 1.8e-18 66.6 0.2 1.8 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30467.1 - 3.6e-08 33.2 0.3 4.6e-08 32.8 0.3 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 EON30467.1 - 0.063 13.3 7.5 1.4 9.0 7.6 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rabaptin PF03528.15 EON30468.1 - 0.014 14.1 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Rabaptin SnoaL_4 PF13577.6 EON30469.1 - 0.00087 19.4 0.1 0.0022 18.1 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like domain Viral_helicase1 PF01443.18 EON30469.1 - 0.042 13.6 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Aldedh PF00171.22 EON30470.1 - 8.7e-15 54.2 1.2 2.8e-10 39.3 0.0 3.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Matrilin_ccoil PF10393.9 EON30471.1 - 0.55 10.1 3.5 3.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Cyt_bd_oxida_I PF01654.17 EON30472.1 - 1.6e-40 139.0 3.7 2.1e-40 138.6 3.7 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF420 PF04238.12 EON30472.1 - 0.036 14.3 0.3 0.41 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF222 PF02720.17 EON30473.1 - 7.2e-41 140.6 13.8 1e-40 140.1 13.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF222) Acetate_kinase PF00871.17 EON30474.1 - 4.9e-139 463.4 0.0 5.6e-139 463.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Trans_reg_C PF00486.28 EON30474.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal PTA_PTB PF01515.19 EON30475.1 - 1.5e-131 438.5 0.0 2.2e-131 437.9 0.0 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 EON30475.1 - 1.3e-26 92.4 0.2 7.9e-26 89.9 0.0 2.5 3 0 0 3 3 3 1 DRTGG domain AAA_26 PF13500.6 EON30475.1 - 9.1e-22 77.9 0.0 1.1e-20 74.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 EON30475.1 - 0.0041 17.2 0.1 0.02 15.0 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FAD-oxidase_C PF02913.19 EON30476.1 - 5.9e-35 121.1 0.0 1.1e-34 120.2 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EON30476.1 - 1.1e-32 112.7 0.2 2.5e-32 111.5 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain TetR_N PF00440.23 EON30477.1 - 2.3e-06 27.3 0.3 4.2e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 EON30477.1 - 0.0053 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF3042 PF11240.8 EON30478.1 - 0.32 11.1 0.6 0.53 10.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) EamA PF00892.20 EON30479.1 - 3.8e-37 127.5 40.1 3.7e-19 69.3 17.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EON30479.1 - 0.49 9.7 5.9 4.3 6.6 6.0 2.0 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF2339 PF10101.9 EON30479.1 - 0.93 8.0 50.7 1.6 7.3 50.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) LysR_substrate PF03466.20 EON30480.1 - 1.2e-28 99.9 5.5 1.6e-28 99.5 5.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EON30480.1 - 2.9e-16 59.1 0.2 6.1e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 EON30480.1 - 0.00051 20.1 0.8 0.0052 16.8 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EON30480.1 - 0.00054 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 EON30480.1 - 0.0084 16.2 0.3 0.021 14.9 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EON30480.1 - 0.032 14.1 0.1 0.12 12.2 0.1 2.1 1 0 0 1 1 1 0 MarR family Bac_luciferase PF00296.20 EON30481.1 - 3.3e-67 227.1 0.9 4e-67 226.9 0.9 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase FCD PF07729.12 EON30482.1 - 1.1e-25 90.5 10.9 1.9e-25 89.7 10.9 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON30482.1 - 3.6e-20 71.4 0.5 3.1e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family AbiEi_4 PF13338.6 EON30482.1 - 9.3e-05 22.5 0.8 0.00032 20.8 0.1 2.3 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 EON30482.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EON30482.1 - 0.00014 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON30482.1 - 0.00017 21.4 3.1 0.0015 18.4 0.1 2.7 2 0 0 2 2 2 1 MarR family DprA_WH PF17782.1 EON30482.1 - 0.0003 20.8 0.4 0.0003 20.8 0.4 2.8 3 1 0 3 3 3 1 DprA winged helix domain HTH_Crp_2 PF13545.6 EON30482.1 - 0.011 15.7 0.1 0.032 14.2 0.1 1.9 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 EON30482.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.6 EON30482.1 - 0.083 13.4 1.1 1.8 9.1 0.0 2.9 3 0 0 3 3 3 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 EON30482.1 - 0.091 12.6 0.9 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain PheRS_DBD1 PF18552.1 EON30482.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 1 PaaX PF07848.12 EON30482.1 - 0.24 11.6 1.5 1.6 9.0 0.1 2.7 3 0 0 3 3 3 0 PaaX-like protein Transp_cyt_pur PF02133.15 EON30483.1 - 4.3e-20 71.9 45.3 3e-19 69.1 45.3 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Isochorismatase PF00857.20 EON30484.1 - 2.1e-44 151.8 0.0 4.3e-44 150.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF4022 PF13214.6 EON30484.1 - 0.037 14.3 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) ABC_membrane PF00664.23 EON30485.1 - 3.5e-40 138.4 6.8 4.3e-40 138.1 6.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON30485.1 - 2.6e-32 112.2 0.0 4.2e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON30485.1 - 4.2e-06 26.4 0.3 0.00011 21.7 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 EON30485.1 - 0.002 17.4 4.3 0.0086 15.3 0.4 2.5 2 0 0 2 2 2 1 ABC transporter transmembrane region Zeta_toxin PF06414.12 EON30485.1 - 0.0032 16.8 0.2 0.0081 15.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EON30485.1 - 0.0046 17.2 0.0 0.017 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON30485.1 - 0.0065 16.1 0.1 0.052 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON30485.1 - 0.0092 16.4 1.4 0.025 15.0 1.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EON30485.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON30485.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EON30485.1 - 0.018 15.5 0.0 0.097 13.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EON30485.1 - 0.061 13.2 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 EON30485.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 EON30485.1 - 0.092 12.5 0.3 22 4.7 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Arabinose_trans PF04602.12 EON30486.1 - 1.3e-170 568.2 43.7 1.7e-170 567.8 43.7 1.2 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 EON30486.1 - 3.7e-140 467.3 0.9 5.4e-140 466.8 0.9 1.2 1 0 0 1 1 1 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 EON30486.1 - 2.4e-36 125.2 0.8 4.5e-36 124.4 0.8 1.5 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain TraP PF07296.11 EON30486.1 - 0.13 11.5 1.8 12 5.0 0.3 2.7 2 0 0 2 2 2 0 TraP protein DUF3377 PF11857.8 EON30486.1 - 0.49 10.4 2.6 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DUF3084 PF11283.8 EON30486.1 - 1.5 8.9 7.3 0.86 9.6 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) Arabinose_trans PF04602.12 EON30487.1 - 7e-200 664.7 31.8 9e-200 664.3 31.8 1.1 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 EON30487.1 - 1.2e-150 501.8 2.4 1.2e-150 501.8 2.4 1.4 2 0 0 2 2 2 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 EON30487.1 - 1.1e-49 168.6 0.2 2e-49 167.8 0.0 1.6 2 0 0 2 2 2 1 Arabinosyltransferase concanavalin like domain PRR18 PF15671.5 EON30487.1 - 3.9 7.3 8.4 4 7.2 5.9 2.1 2 0 0 2 2 2 0 Proline-rich protein family 18 Tmemb_14 PF03647.13 EON30487.1 - 7.3 7.4 10.4 5 7.9 0.2 3.8 3 1 0 3 3 3 0 Transmembrane proteins 14C Ferritin PF00210.24 EON30488.1 - 6.6e-24 84.5 0.0 8.1e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Helicase_C_4 PF13871.6 EON30488.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue DICT PF10069.9 EON30489.1 - 7.2e-11 42.0 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Sensory domain in DIguanylate Cyclases and Two-component system EAL PF00563.20 EON30489.1 - 2.2e-10 40.5 0.8 4.7e-10 39.4 0.8 1.6 1 1 0 1 1 1 1 EAL domain Arabinose_trans PF04602.12 EON30490.1 - 1.8e-171 571.1 44.7 1.8e-171 571.1 44.7 1.7 2 0 0 2 2 2 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 EON30490.1 - 1.6e-143 478.4 3.4 2.1e-143 478.0 3.4 1.1 1 0 0 1 1 1 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 EON30490.1 - 9.5e-41 139.6 1.8 1.8e-40 138.7 1.8 1.5 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain DUF3185 PF11381.8 EON30490.1 - 0.5 10.4 7.1 4.2 7.5 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Arabinose_trans PF04602.12 EON30491.1 - 2e-180 600.6 36.2 3.2e-180 599.9 36.2 1.4 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 EON30491.1 - 4e-145 483.7 6.5 5.5e-145 483.2 6.5 1.2 1 0 0 1 1 1 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 EON30491.1 - 1.9e-47 161.3 0.2 4.1e-47 160.3 0.2 1.6 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain Adeno_PX PF05829.12 EON30491.1 - 0.0018 18.1 1.7 0.79 9.6 0.1 3.0 2 0 0 2 2 2 2 Adenovirus late L2 mu core protein (Protein X) ABC2_membrane PF01061.24 EON30492.1 - 2.7e-22 79.2 10.4 2.7e-22 79.2 10.4 1.6 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON30492.1 - 1.7e-15 57.0 7.4 1.7e-15 57.0 7.4 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON30492.1 - 0.0029 16.9 15.6 0.02 14.2 15.5 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EON30492.1 - 0.071 13.1 7.2 0.01 15.8 3.4 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Phage_holin_3_6 PF07332.11 EON30492.1 - 4.8 7.3 25.9 1.8 8.7 13.6 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_tran PF00005.27 EON30493.1 - 1.7e-26 93.3 0.0 2.7e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON30493.1 - 6.2e-13 49.2 0.2 1.3e-06 28.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 EON30493.1 - 2.2e-05 24.2 0.1 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KdpD PF02702.17 EON30493.1 - 0.0015 18.0 0.0 0.0042 16.6 0.0 1.7 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain AAA_15 PF13175.6 EON30493.1 - 0.0034 17.1 0.0 0.081 12.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EON30493.1 - 0.0058 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EON30493.1 - 0.011 16.2 0.1 0.072 13.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EON30493.1 - 0.012 16.2 0.1 0.019 15.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON30493.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF4162 PF13732.6 EON30493.1 - 0.015 16.0 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_29 PF13555.6 EON30493.1 - 0.023 14.4 0.3 0.069 12.9 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EON30493.1 - 0.034 14.4 0.2 0.11 12.8 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EON30493.1 - 0.039 14.3 3.7 0.053 13.9 2.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 EON30493.1 - 0.05 13.0 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 EON30493.1 - 0.064 12.6 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 EON30493.1 - 0.099 12.6 0.1 0.35 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EON30493.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EON30493.1 - 0.13 12.6 1.3 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2304 PF10066.9 EON30495.1 - 2.4e-23 82.4 4.7 2.6e-23 82.2 4.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2304) DUF4199 PF13858.6 EON30495.1 - 0.0016 18.9 1.4 0.002 18.6 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) YebO PF13974.6 EON30495.1 - 0.075 13.1 0.5 0.17 12.0 0.5 1.5 1 0 0 1 1 1 0 YebO-like protein DUF2109 PF09882.9 EON30495.1 - 0.46 10.5 4.9 2.2 8.3 4.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2109) DUF3937 PF13073.6 EON30495.1 - 0.46 10.6 5.2 0.16 12.1 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3937) Wzy_C_2 PF11846.8 EON30495.1 - 1 9.3 3.3 0.54 10.2 0.7 1.7 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF2070 PF09843.9 EON30495.1 - 2.1 6.5 5.8 2.3 6.4 5.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FixQ PF05545.11 EON30495.1 - 5.9 6.9 13.2 21 5.2 0.4 3.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Oxidored_q2 PF00420.24 EON30495.1 - 6 6.5 8.0 20 4.9 8.1 1.9 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Glycos_transf_2 PF00535.26 EON30496.1 - 7e-24 84.5 0.0 1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON30496.1 - 0.00073 19.5 0.5 0.00091 19.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EON30496.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EON30497.1 - 9.6e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON30497.1 - 2.4e-06 27.6 0.8 3.3e-06 27.2 0.4 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON30497.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON30497.1 - 0.086 12.7 0.6 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Polysacc_synt PF01943.17 EON30498.1 - 0.0001 21.8 7.2 0.0001 21.8 7.2 2.0 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein DUF4389 PF14333.6 EON30498.1 - 6.3 6.8 10.4 0.54 10.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Peptidase_M1 PF01433.20 EON30499.1 - 1.1e-27 97.0 0.2 2.2e-27 96.1 0.2 1.5 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EON30499.1 - 2.2e-15 57.4 0.0 4.4e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EON30499.1 - 0.059 13.8 2.7 1.7 9.1 2.7 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_MA_2 PF13485.6 EON30499.1 - 0.06 13.0 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily DoxX PF07681.12 EON30500.1 - 1.3e-21 76.9 7.3 1.3e-21 76.9 7.3 1.5 2 0 0 2 2 2 1 DoxX DoxX_2 PF13564.6 EON30500.1 - 0.00037 20.5 7.0 0.00053 20.1 6.7 1.4 1 1 0 1 1 1 1 DoxX-like family DoxD PF04173.13 EON30500.1 - 0.0034 17.3 4.4 0.015 15.2 1.7 2.0 2 0 0 2 2 2 1 TQO small subunit DoxD TPPK_C PF12555.8 EON30500.1 - 0.22 11.6 6.5 0.83 9.8 3.8 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF4212 PF13937.6 EON30500.1 - 5.4 7.5 7.5 1.8 9.0 3.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) TPR_2 PF07719.17 EON30501.1 - 0.061 13.5 0.2 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Clp_N PF02861.20 EON30503.1 - 2.6e-18 65.9 1.3 1e-11 44.8 0.1 2.7 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component FGE-sulfatase PF03781.16 EON30504.1 - 2.3e-34 119.2 1.0 2.9e-26 92.6 0.3 2.3 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EON30504.1 - 7.1e-09 36.3 6.8 1.3e-08 35.4 4.7 2.4 2 1 0 2 2 2 1 DinB superfamily Methyltransf_33 PF10017.9 EON30505.1 - 1.1e-102 343.3 0.0 1.3e-102 343.1 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 EON30505.1 - 0.00061 20.4 0.0 0.0068 17.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30505.1 - 0.17 12.7 0.0 0.48 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Bac_luciferase PF00296.20 EON30506.1 - 1.3e-42 146.3 0.7 2.1e-42 145.7 0.7 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase PLDc_N PF13396.6 EON30507.1 - 5.7e-08 32.6 5.8 5.7e-08 32.6 5.8 1.7 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal SHOCT PF09851.9 EON30507.1 - 8.2e-06 25.4 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Short C-terminal domain DUF2208 PF09973.9 EON30507.1 - 0.031 13.9 0.7 0.039 13.6 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF4834 PF16118.5 EON30507.1 - 1.1 10.3 3.1 11 7.0 3.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5542 PF17696.1 EON30507.1 - 2.9 8.1 7.4 18 5.6 4.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5542) DUF389 PF04087.14 EON30508.1 - 4.6e-29 101.3 19.3 4.6e-29 101.3 19.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF389) Imm17 PF15562.6 EON30508.1 - 0.73 9.7 0.1 0.73 9.7 0.1 3.1 3 1 0 3 3 3 0 Immunity protein 17 PT-VENN PF04829.13 EON30508.1 - 3.8 7.7 6.4 16 5.7 1.4 2.8 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif DUF2304 PF10066.9 EON30508.1 - 8.6 6.6 10.8 2.5 8.3 0.3 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Alkyl_sulf_dimr PF14863.6 EON30509.1 - 5.7e-64 214.7 0.1 1.8e-63 213.1 0.1 1.9 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 EON30509.1 - 2.9e-41 141.6 5.8 5.9e-41 140.7 5.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 EON30509.1 - 2.5e-36 124.7 0.7 4.5e-36 123.9 0.7 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 EON30509.1 - 2.7e-06 27.0 0.3 6.8e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SCP2 PF02036.17 EON30509.1 - 0.0026 18.2 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family MDMPI_C PF07398.11 EON30509.1 - 0.018 15.9 3.6 0.018 15.9 3.6 2.6 3 0 0 3 3 3 0 MDMPI C-terminal domain SCP2_2 PF13530.6 EON30509.1 - 0.02 15.3 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 Sterol carrier protein domain Phos_pyr_kin PF08543.12 EON30510.1 - 1.6e-84 283.1 0.0 1.9e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EON30510.1 - 5.5e-10 39.0 0.1 1.4e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EON30510.1 - 0.016 14.7 2.3 0.029 13.8 2.3 1.5 1 1 0 1 1 1 0 Carbohydrate kinase MgtC PF02308.16 EON30510.1 - 0.048 14.0 0.9 0.11 12.8 0.9 1.5 1 0 0 1 1 1 0 MgtC family Hydrolase_6 PF13344.6 EON30512.1 - 3.3e-20 72.1 0.0 9e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON30512.1 - 1.6e-17 63.3 0.4 5.5e-17 61.6 0.4 2.0 1 0 0 1 1 1 1 HAD-hyrolase-like GNAT_like PF18407.1 EON30512.1 - 1.5e-09 38.1 7.2 1.1e-08 35.3 7.2 2.7 1 0 0 1 1 1 1 GCN5-related N-acetyltransferase like domain Hydrolase PF00702.26 EON30512.1 - 6.3e-05 23.4 0.6 0.00014 22.2 0.6 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_2 PF07719.17 EON30512.1 - 0.0032 17.5 5.5 1.3 9.3 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EON30512.1 - 0.035 14.4 4.0 11 6.4 1.5 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 EON30512.1 - 0.039 14.2 0.4 0.14 12.4 0.4 2.0 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_19 PF14559.6 EON30512.1 - 0.56 10.8 9.0 10 6.7 1.1 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EON30512.1 - 0.81 10.7 18.4 0.25 12.3 1.4 5.7 3 1 2 5 5 5 0 Tetratricopeptide repeat FtsJ PF01728.19 EON30514.1 - 7.2e-20 71.8 0.0 9.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 EON30514.1 - 5.8e-11 41.9 0.2 1.8e-10 40.4 0.2 1.9 1 0 0 1 1 1 1 S4 domain NAD_kinase PF01513.21 EON30515.1 - 7.9e-63 212.4 0.1 8.5e-63 212.3 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EON30515.1 - 0.0024 17.5 0.0 0.0057 16.3 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SMC_N PF02463.19 EON30516.1 - 1.2e-16 60.9 0.0 1.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON30516.1 - 4.4e-07 30.6 0.0 9.2e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON30516.1 - 3.9e-06 27.2 0.2 0.00043 20.6 0.3 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EON30516.1 - 4.7e-05 23.3 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON30516.1 - 0.011 15.4 0.2 0.047 13.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain LcrG PF07216.12 EON30516.1 - 0.011 15.6 2.9 0.052 13.5 0.5 2.8 2 0 0 2 2 2 0 LcrG protein HET-S PF17108.5 EON30516.1 - 0.018 14.8 2.1 0.018 14.8 2.1 2.0 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic AAA_5 PF07728.14 EON30516.1 - 0.039 14.0 0.3 4.4 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EON30516.1 - 0.052 13.3 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 EON30516.1 - 0.064 13.0 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EON30516.1 - 0.11 13.0 0.1 3.7 8.1 0.0 2.6 2 1 0 2 2 2 0 ABC transporter DivIC PF04977.15 EON30516.1 - 0.14 12.0 5.3 20 5.1 0.3 4.5 5 0 0 5 5 5 0 Septum formation initiator AAA PF00004.29 EON30516.1 - 0.15 12.5 0.4 30 5.0 0.1 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON30516.1 - 0.19 11.6 2.1 1.7 8.6 0.1 2.8 3 0 0 3 3 3 0 NACHT domain DHR10 PF18595.1 EON30516.1 - 0.28 11.2 5.4 10 6.2 0.4 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain TPPK_C PF12555.8 EON30517.1 - 1.7e-18 66.4 7.3 3.6e-18 65.3 7.3 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal MctB PF11382.8 EON30518.1 - 1.4e-89 300.8 12.6 1.6e-89 300.7 12.6 1.0 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB CTP_synth_N PF06418.14 EON30519.1 - 1.6e-117 391.5 0.0 2.1e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EON30519.1 - 2.2e-43 148.3 0.0 3.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EON30519.1 - 8.8e-06 25.6 0.1 4.5e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 EON30519.1 - 0.0096 16.0 0.0 0.03 14.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NUDIX PF00293.28 EON30520.1 - 1.6e-13 50.9 2.1 2.2e-13 50.4 0.8 1.8 1 1 1 2 2 2 1 NUDIX domain Phage_integrase PF00589.22 EON30521.1 - 1.4e-44 152.0 0.0 1.8e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EON30521.1 - 2.9e-23 82.0 0.9 1.1e-22 80.1 0.5 2.2 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EON30521.1 - 4.4e-05 23.9 0.0 0.00029 21.3 0.0 2.3 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EON30521.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 Phage integrase SAM-like domain Integrase_1 PF12835.7 EON30521.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Integrase AAA_31 PF13614.6 EON30522.1 - 3.4e-60 203.0 0.0 4.3e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EON30522.1 - 5.1e-25 88.0 0.0 7.5e-24 84.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EON30522.1 - 1.4e-12 47.6 0.0 7e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EON30522.1 - 1.8e-10 40.8 0.0 1.3e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EON30522.1 - 3e-10 39.8 0.7 2.9e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 EON30522.1 - 2.2e-08 33.9 0.0 4.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 EON30522.1 - 4.1e-07 29.5 0.1 9.2e-07 28.3 0.1 1.7 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 EON30522.1 - 1.9e-05 24.1 0.2 7.9e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 VirC1 protein MeaB PF03308.16 EON30522.1 - 0.0017 17.4 0.9 0.0038 16.2 0.2 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1611 PF07755.11 EON30522.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain CLP1_P PF16575.5 EON30522.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SMC_ScpA PF02616.14 EON30523.1 - 1.7e-59 201.6 0.0 2e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Segregation and condensation protein ScpA SMC_ScpB PF04079.16 EON30524.1 - 5.4e-51 172.4 0.0 6.6e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_15 PF12324.8 EON30524.1 - 0.00017 21.5 2.8 0.007 16.3 0.3 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of alkylmercury lyase TrmB PF01978.19 EON30524.1 - 0.0034 17.2 0.2 0.25 11.3 0.1 2.3 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB PseudoU_synth_2 PF00849.22 EON30525.1 - 1.7e-19 70.5 0.0 2.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EON30525.1 - 8.9e-13 47.7 0.3 3.2e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 EON30525.1 - 0.013 15.3 0.2 0.03 14.1 0.2 1.6 1 0 0 1 1 1 0 S4 domain FlbD PF06289.11 EON30525.1 - 0.022 14.3 0.1 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins Cytidylate_kin PF02224.18 EON30526.1 - 5.7e-75 251.7 0.6 6.5e-75 251.5 0.6 1.0 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 EON30526.1 - 5.5e-06 27.0 0.0 8.4e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EON30526.1 - 0.00074 19.7 1.0 1.1 9.4 0.1 2.2 2 1 0 2 2 2 2 Cytidylate kinase-like family AAA_17 PF13207.6 EON30526.1 - 0.0012 19.3 0.2 0.33 11.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EON30526.1 - 0.0041 17.3 0.6 0.079 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF4478 PF14793.6 EON30526.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases ABC_tran PF00005.27 EON30526.1 - 0.019 15.5 0.0 0.066 13.7 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EON30526.1 - 0.021 14.5 0.5 0.046 13.4 0.5 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON30526.1 - 0.026 14.9 1.1 0.039 14.3 1.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SKI PF01202.22 EON30526.1 - 0.041 14.0 0.4 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_5 PF07728.14 EON30526.1 - 0.067 13.2 0.2 0.26 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EON30526.1 - 0.11 12.8 0.2 0.32 11.3 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EON30526.1 - 0.13 12.7 0.2 0.35 11.3 0.1 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CoaE PF01121.20 EON30526.1 - 0.13 11.9 0.4 0.23 11.1 0.4 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase RNA_helicase PF00910.22 EON30526.1 - 0.16 12.3 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase dNK PF01712.19 EON30526.1 - 0.26 11.1 0.0 1 9.2 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_6 PF12774.7 EON30526.1 - 0.3 10.0 0.3 0.5 9.3 0.3 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MMR_HSR1 PF01926.23 EON30527.1 - 2e-50 169.7 1.4 2.4e-25 88.8 0.0 2.5 3 0 0 3 3 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EON30527.1 - 3.6e-31 107.8 0.0 1.9e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 EON30527.1 - 1.8e-25 89.0 0.0 3.6e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 EON30527.1 - 7.2e-24 84.4 0.1 4.9e-09 36.0 0.0 4.8 2 2 1 3 3 3 3 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EON30527.1 - 2.1e-12 46.9 0.1 7.8e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EON30527.1 - 2.9e-12 46.8 1.3 0.01 15.8 0.3 3.9 3 1 0 3 3 3 3 RsgA GTPase Dynamin_N PF00350.23 EON30527.1 - 3e-12 46.9 0.3 0.017 15.2 0.1 4.1 3 1 1 4 4 4 3 Dynamin family Roc PF08477.13 EON30527.1 - 3.8e-10 40.0 0.1 0.00021 21.5 0.0 2.9 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EON30527.1 - 7.5e-09 35.4 0.0 0.0068 16.0 0.0 2.9 2 1 0 2 2 2 2 Ras family ABC_tran PF00005.27 EON30527.1 - 3e-07 31.0 0.0 0.062 13.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EON30527.1 - 5.1e-06 27.0 1.9 0.014 15.8 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain SRPRB PF09439.10 EON30527.1 - 5.4e-06 26.0 0.0 0.022 14.2 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EON30527.1 - 2.6e-05 24.0 0.0 0.017 14.9 0.0 3.4 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 EON30527.1 - 2.6e-05 23.7 0.0 0.13 11.8 0.0 2.8 2 2 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 EON30527.1 - 5.2e-05 22.7 0.0 0.1 12.0 0.0 2.7 3 0 0 3 3 3 2 Bacterial TniB protein AAA_33 PF13671.6 EON30527.1 - 0.00017 21.8 0.7 0.003 17.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EON30527.1 - 0.00044 19.9 0.5 9.3 5.8 0.0 4.0 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EON30527.1 - 0.00096 18.9 0.0 1.1 9.0 0.0 2.4 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 EON30527.1 - 0.0013 18.6 0.8 0.38 10.7 0.0 2.9 2 1 1 3 3 3 1 NTPase AAA_22 PF13401.6 EON30527.1 - 0.0016 18.7 0.1 1 9.7 0.0 3.0 2 2 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EON30527.1 - 0.0022 17.9 0.1 0.12 12.2 0.1 2.5 2 1 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 EON30527.1 - 0.0026 18.3 0.1 3.2 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EON30527.1 - 0.0028 16.7 8.7 0.11 11.4 0.3 3.6 4 0 0 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EON30527.1 - 0.0042 17.3 0.2 2.2 8.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EON30527.1 - 0.011 15.5 0.0 5.2 6.8 0.0 3.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EON30527.1 - 0.012 16.0 0.0 5.9 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MMR_HSR1_Xtn PF16897.5 EON30527.1 - 0.022 14.8 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_29 PF13555.6 EON30527.1 - 0.03 14.0 0.1 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain FixH PF05751.11 EON30527.1 - 0.036 14.1 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 FixH NB-ARC PF00931.22 EON30527.1 - 0.063 12.4 0.0 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EON30527.1 - 0.089 12.7 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea GBP PF02263.19 EON30527.1 - 0.09 12.0 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.10 EON30527.1 - 0.098 12.1 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MobB PF03205.14 EON30527.1 - 0.17 11.8 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Transgly_assoc PF04226.13 EON30528.1 - 2e-05 24.7 8.2 2e-05 24.7 8.2 2.2 2 1 0 2 2 2 1 Transglycosylase associated protein Bax1-I PF01027.20 EON30528.1 - 0.27 11.0 6.1 0.33 10.8 6.1 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Phage_holin_2_1 PF04971.12 EON30528.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.6 2 1 1 3 3 3 0 Bacteriophage P21 holin S Gly-zipper_Omp PF13488.6 EON30528.1 - 1 9.4 10.9 0.55 10.3 2.8 2.3 1 1 0 2 2 2 0 Glycine zipper Phage_holin_5_1 PF06946.11 EON30528.1 - 4.6 7.7 8.4 0.99 9.8 3.6 2.1 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 FAD_binding_7 PF03441.14 EON30529.1 - 2.3e-68 229.6 9.3 1.1e-64 217.6 7.0 2.2 1 1 1 2 2 2 2 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EON30529.1 - 7.3e-26 91.1 0.0 1.4e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase FKBP_C PF00254.28 EON30530.1 - 1.3e-23 83.1 0.0 1.7e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Citrate_synt PF00285.21 EON30531.1 - 9.7e-135 449.3 0.0 1.1e-134 449.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PfkB PF00294.24 EON30532.1 - 2.1e-44 152.1 0.0 2.5e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4567 PF15131.6 EON30532.1 - 0.051 13.6 1.0 0.15 12.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) CT_C_D PF02682.16 EON30533.1 - 2.1e-54 184.4 0.0 2.3e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D DUF1799 PF08809.11 EON30533.1 - 0.062 13.5 0.0 3.4 7.9 0.0 2.6 3 0 0 3 3 3 0 Phage related hypothetical protein (DUF1799) CT_A_B PF02626.15 EON30534.1 - 9.5e-80 268.0 1.9 1.1e-79 267.8 1.9 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B Phage_holin_3_6 PF07332.11 EON30535.1 - 6.7e-31 106.7 11.0 7.4e-31 106.5 11.0 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SirB PF04247.12 EON30535.1 - 0.048 13.8 1.1 0.075 13.1 1.1 1.2 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF2207 PF09972.9 EON30535.1 - 0.12 11.1 0.2 0.12 11.1 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4175 PF13779.6 EON30535.1 - 0.18 9.7 2.4 0.27 9.1 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) YtpI PF14007.6 EON30535.1 - 0.24 11.5 5.0 0.78 9.9 5.0 1.8 1 1 0 1 1 1 0 YtpI-like protein DUF973 PF06157.11 EON30535.1 - 0.27 10.2 3.0 0.31 10.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3618 PF12277.8 EON30536.1 - 1.3e-09 38.2 5.4 2.1e-09 37.5 5.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) DUF883 PF05957.13 EON30536.1 - 0.0085 16.7 1.2 0.0099 16.5 1.2 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) CwsA PF10814.8 EON30536.1 - 0.011 15.9 2.5 0.012 15.7 2.5 1.2 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF1206 PF06724.11 EON30536.1 - 0.019 15.0 0.7 0.024 14.7 0.7 1.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) PilW PF16074.5 EON30536.1 - 0.036 14.1 0.0 0.039 14.0 0.0 1.0 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W DotU PF09850.9 EON30536.1 - 0.042 13.6 0.1 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU Gram_pos_anchor PF00746.21 EON30536.1 - 0.066 13.2 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4235 PF14019.6 EON30537.1 - 1.7e-24 85.7 0.4 1.9e-24 85.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) INSIG PF07281.12 EON30537.1 - 0.079 12.6 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUF2236 PF09995.9 EON30538.1 - 2.6e-51 175.0 2.2 4.4e-51 174.3 2.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DIOX_N PF14226.6 EON30539.1 - 8.2e-24 84.6 0.0 1.3e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EON30539.1 - 4.9e-17 62.3 0.0 8.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_3 PF05977.13 EON30540.1 - 2e-31 109.0 41.6 2.5e-31 108.7 41.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EON30540.1 - 8.7e-19 67.6 63.5 9e-19 67.6 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Putative_PNPOx PF01243.20 EON30542.1 - 2.1e-22 79.1 0.1 3.6e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EON30542.1 - 3.7e-17 62.1 3.2 6.3e-17 61.4 3.2 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EON30542.1 - 0.027 15.1 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EON30542.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Citrate_synt PF00285.21 EON30543.1 - 2.4e-84 283.5 0.1 4.7e-83 279.2 0.1 2.0 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Fe-ADH PF00465.19 EON30543.1 - 0.078 11.8 0.7 0.38 9.5 0.1 1.9 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase DUF2458 PF10454.9 EON30543.1 - 0.26 10.9 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Aminotran_5 PF00266.19 EON30544.1 - 1.9e-14 53.4 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF3071 PF11268.8 EON30545.1 - 2e-58 197.2 0.9 2.6e-58 196.8 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) HTH_31 PF13560.6 EON30545.1 - 0.12 12.8 0.6 0.12 12.8 0.6 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2537 PF10801.8 EON30547.1 - 3.7e-17 62.3 19.3 4.5e-17 62.0 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2537) TrbC PF04956.13 EON30547.1 - 0.74 10.1 12.8 0.21 11.8 6.4 2.0 1 1 1 2 2 2 0 TrbC/VIRB2 family 5TM-5TMR_LYT PF07694.12 EON30547.1 - 1.8 8.1 11.2 2 7.9 11.2 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT SpoU_methylase PF00588.19 EON30548.1 - 3e-29 102.0 0.0 3.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Acetyltransf_9 PF13527.7 EON30549.1 - 2.1e-28 99.0 0.0 4.8e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 EON30549.1 - 3.1e-17 63.4 0.1 6.4e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 EON30549.1 - 2.2e-13 50.5 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_7 PF13508.7 EON30549.1 - 0.0025 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON30549.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_M15 PF01427.17 EON30550.1 - 4e-52 176.9 0.0 4.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase DNA_pol3_delta2 PF13177.6 EON30551.1 - 2.5e-38 131.4 0.0 3.5e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 EON30551.1 - 4.7e-13 49.3 1.3 7.9e-13 48.5 1.3 1.4 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA PF00004.29 EON30551.1 - 1.1e-09 38.8 0.0 2.8e-09 37.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON30551.1 - 2.5e-07 31.0 0.0 7.2e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON30551.1 - 4.1e-05 23.4 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EON30551.1 - 6e-05 23.5 1.0 0.0044 17.4 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 EON30551.1 - 0.006 16.3 0.0 0.018 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EON30551.1 - 0.017 15.4 0.0 0.094 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EON30551.1 - 0.047 13.7 0.0 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EON30551.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EON30551.1 - 0.09 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EON30551.1 - 0.099 12.7 0.0 0.78 9.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON30551.1 - 0.12 12.6 0.0 4.4 7.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 EON30551.1 - 0.22 9.4 0.0 0.32 8.9 0.0 1.1 1 0 0 1 1 1 0 Helicase GT87 PF09594.10 EON30552.1 - 2.9e-57 194.2 27.3 2.9e-57 194.2 27.3 3.2 3 1 0 3 3 3 1 Glycosyltransferase family 87 Aminotran_MocR PF12897.7 EON30553.1 - 8.8e-188 624.3 0.0 1e-187 624.1 0.0 1.0 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 EON30553.1 - 7.4e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II BAT PF15915.5 EON30553.1 - 0.12 12.2 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 GAF and HTH_10 associated domain Sex_peptide PF08138.11 EON30553.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 2 0 0 2 2 2 0 Sex peptide (SP) family NmrA PF05368.13 EON30554.1 - 1.2e-40 139.5 0.0 1.5e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EON30554.1 - 6.2e-16 58.8 0.2 8.9e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON30554.1 - 0.00037 20.0 0.2 0.00054 19.5 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1702 PF08012.11 EON30554.1 - 0.04 12.8 0.7 0.056 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) TrkA_N PF02254.18 EON30554.1 - 0.062 13.6 0.3 0.095 13.0 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain DNA_primase_S PF01896.19 EON30555.1 - 3.4e-07 30.5 0.0 7.1e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 DNA primase small subunit DNA_ligase_A_M PF01068.21 EON30556.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EON30556.1 - 4.2e-14 52.9 0.0 7.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region tRNA-synt_1c PF00749.21 EON30557.1 - 4.2e-49 167.1 0.0 5.1e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain AbiEi_4 PF13338.6 EON30557.1 - 0.15 12.3 0.9 3.8 7.8 0.1 3.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin tRNA-synt_1f PF01921.18 EON30557.1 - 0.28 10.1 0.0 2.5 7.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF21 PF01595.20 EON30558.1 - 7.2e-41 139.8 2.0 9.8e-41 139.4 2.0 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EON30558.1 - 4.8e-07 30.1 1.5 8.6e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 CBS domain Prot_ATP_OB_N PF17758.1 EON30558.1 - 0.013 15.1 0.1 0.033 13.9 0.1 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Reductase_C PF14759.6 EON30558.1 - 0.05 14.2 0.1 5.8 7.5 0.0 3.2 3 0 0 3 3 3 0 Reductase C-terminal Apc13p PF05839.11 EON30558.1 - 0.084 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Apc13p protein DUF21 PF01595.20 EON30559.1 - 9.3e-38 129.7 0.4 1.3e-37 129.2 0.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EON30559.1 - 5.7e-17 61.5 1.5 1.4e-16 60.2 0.1 2.3 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EON30559.1 - 6e-14 52.2 0.1 9.4e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 CBS domain EI24 PF07264.11 EON30559.1 - 0.019 15.2 3.8 0.5 10.6 0.4 2.2 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Aldolase_II PF00596.21 EON30560.1 - 7.5e-43 146.6 0.7 8.8e-43 146.4 0.7 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PfkB PF00294.24 EON30561.1 - 4.3e-44 151.0 0.9 5.7e-44 150.6 0.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase adh_short PF00106.25 EON30562.1 - 4.7e-24 84.9 0.0 7.1e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON30562.1 - 1.8e-20 73.5 0.0 2.3e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EamA PF00892.20 EON30563.1 - 1.3e-09 38.4 16.9 1.3e-09 38.4 16.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family YqhR PF11085.8 EON30563.1 - 0.26 11.2 1.8 0.7 9.8 1.8 1.8 1 1 0 1 1 1 0 Conserved membrane protein YqhR SnoaL_2 PF12680.7 EON30564.1 - 3.6e-07 30.8 0.8 4.6e-07 30.4 0.8 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 EON30565.1 - 1.1e-44 152.7 0.0 1.4e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON30565.1 - 8.8e-32 110.1 0.0 1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON30565.1 - 2e-11 44.2 0.1 2.4e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EON30565.1 - 0.0032 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 EON30565.1 - 0.0073 15.7 0.2 0.0092 15.4 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Toprim_3 PF13362.6 EON30565.1 - 0.02 15.3 0.3 0.037 14.4 0.3 1.4 1 0 0 1 1 1 0 Toprim domain Mce4_CUP1 PF11887.8 EON30565.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Rossmann-like PF10727.9 EON30565.1 - 0.14 12.0 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain HTH_1 PF00126.27 EON30566.1 - 1.3e-14 53.9 3.3 2.2e-14 53.1 3.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EON30566.1 - 2.3e-13 50.0 3.1 2.9e-13 49.7 1.5 2.0 2 1 0 2 2 2 1 LysR substrate binding domain AHSA1 PF08327.11 EON30567.1 - 2.8e-13 50.2 0.2 3.2e-13 50.0 0.2 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EON30567.1 - 0.00018 21.8 2.7 0.00023 21.5 2.7 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AMP-binding PF00501.28 EON30568.1 - 3.3e-73 246.7 0.0 3.9e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30568.1 - 2.4e-13 50.8 0.5 2.3e-12 47.7 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Chorismate_bind PF00425.18 EON30569.1 - 7.9e-71 238.6 0.0 1e-70 238.3 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme PP-binding PF00550.25 EON30570.1 - 2e-13 50.5 2.3 2.3e-13 50.3 2.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl-CoA_dh_1 PF00441.24 EON30571.1 - 2.3e-32 112.3 5.8 3.6e-32 111.7 5.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON30571.1 - 1.3e-13 50.9 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON30571.1 - 1.5e-08 35.0 2.3 3.6e-08 33.7 2.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON30571.1 - 0.034 14.8 0.0 0.39 11.4 0.0 2.6 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain WES_acyltransf PF03007.16 EON30572.1 - 1.5e-12 47.8 4.0 2.8e-12 47.0 0.6 2.2 1 1 1 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON30572.1 - 0.015 15.3 0.1 0.16 11.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1298) Condensation PF00668.20 EON30572.1 - 0.018 13.7 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Condensation domain Peripla_BP_2 PF01497.18 EON30574.1 - 2e-22 80.0 0.1 2.4e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein AICARFT_IMPCHas PF01808.18 EON30574.1 - 0.081 12.4 0.0 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 AICARFT/IMPCHase bienzyme K_oxygenase PF13434.6 EON30575.1 - 8.9e-100 334.1 0.0 1.1e-99 333.9 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EON30575.1 - 1.6e-05 24.3 0.0 0.0012 18.1 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON30575.1 - 0.00064 19.0 0.0 0.3 10.3 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyridoxal_deC PF00282.19 EON30576.1 - 9e-59 199.1 0.0 1.1e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EON30576.1 - 7.8e-09 35.2 0.0 1.3e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EON30576.1 - 5.9e-05 22.5 0.2 9.8e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EON30576.1 - 8.7e-05 21.6 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 EON30576.1 - 0.00028 19.7 0.0 0.00045 19.0 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 EON30576.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II OKR_DC_1 PF01276.20 EON30576.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Polbeta PF18765.1 EON30576.1 - 0.21 11.7 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Condensation PF00668.20 EON30577.1 - 1.9e-16 59.8 0.0 1.7e-15 56.6 0.0 1.9 1 1 0 1 1 1 1 Condensation domain Penicil_amidase PF01804.18 EON30578.1 - 7.1e-155 517.7 6.5 8e-155 517.5 6.5 1.0 1 0 0 1 1 1 1 Penicillin amidase IucA_IucC PF04183.12 EON30579.1 - 2.6e-71 240.0 0.0 4e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EON30579.1 - 8.5e-33 114.1 0.0 1.7e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Acetyltransf_8 PF13523.6 EON30580.1 - 4.1e-32 110.9 0.2 5.4e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON30580.1 - 0.16 12.6 0.0 0.39 11.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EON30581.1 - 7.5e-91 304.8 0.1 1.1e-90 304.3 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EON30581.1 - 2.3e-29 102.4 0.0 3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 EON30581.1 - 1.4e-08 35.6 0.1 8.6e-08 33.1 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EON30581.1 - 3.5e-07 30.5 0.0 1.4e-06 28.6 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site HNH PF01844.23 EON30582.1 - 0.059 13.6 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 HNH endonuclease AAA_2 PF07724.14 EON30583.1 - 2.2e-52 177.6 0.2 6.9e-50 169.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EON30583.1 - 3.8e-36 123.1 3.7 2.6e-35 120.5 0.7 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EON30583.1 - 1.6e-25 88.9 0.1 1.6e-25 88.9 0.1 2.6 3 1 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EON30583.1 - 1.8e-24 85.6 6.6 1.9e-11 43.9 0.1 4.0 4 0 0 4 4 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 EON30583.1 - 3.5e-24 85.7 1.4 1.5e-12 48.1 0.0 3.8 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON30583.1 - 3.3e-17 62.8 0.9 9.8e-12 45.0 0.0 4.0 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON30583.1 - 1.5e-11 45.0 9.3 2.1e-06 28.2 0.1 4.8 4 2 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EON30583.1 - 2.5e-08 34.3 0.7 0.039 14.2 0.0 4.8 3 2 2 5 5 5 2 AAA domain Sigma54_activat PF00158.26 EON30583.1 - 3.8e-08 33.2 0.0 1.4e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EON30583.1 - 2.3e-06 27.5 0.0 0.061 13.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EON30583.1 - 4.3e-06 26.8 2.0 0.45 10.4 0.0 4.0 4 1 0 4 4 4 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EON30583.1 - 2e-05 24.1 0.0 0.46 9.8 0.0 3.3 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EON30583.1 - 4.2e-05 23.1 0.0 0.12 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EON30583.1 - 4.9e-05 23.9 0.8 0.19 12.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EON30583.1 - 5.7e-05 23.2 0.0 0.25 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EON30583.1 - 8.8e-05 22.0 0.0 0.59 9.5 0.0 3.5 2 1 1 3 3 3 1 Bacterial TniB protein Roc PF08477.13 EON30583.1 - 0.00021 21.5 0.0 0.68 10.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 EON30583.1 - 0.00023 21.1 0.0 0.63 9.9 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON30583.1 - 0.00024 21.1 0.0 0.056 13.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 EON30583.1 - 0.00028 20.7 0.7 0.77 9.5 0.0 4.4 3 1 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 EON30583.1 - 0.00033 21.2 5.0 2.2 8.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EON30583.1 - 0.00037 20.8 0.0 1.8 8.8 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EON30583.1 - 0.00059 19.6 0.0 0.8 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EON30583.1 - 0.00078 19.8 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 EON30583.1 - 0.00082 19.4 0.1 1.6 8.8 0.0 2.9 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EON30583.1 - 0.0011 18.9 0.1 1.7 8.5 0.0 2.8 3 0 0 3 3 2 1 RsgA GTPase AAA_33 PF13671.6 EON30583.1 - 0.0012 19.0 0.2 1.4 9.1 0.0 3.4 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EON30583.1 - 0.0074 15.6 2.3 1.1 8.4 0.0 3.5 3 1 0 3 3 3 1 Zeta toxin ABC_tran PF00005.27 EON30583.1 - 0.01 16.3 0.3 1.5 9.3 0.0 2.9 3 0 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 EON30583.1 - 0.021 14.4 0.1 2 8.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain Fez1 PF06818.15 EON30583.1 - 0.021 15.3 6.8 0.05 14.1 6.8 1.5 1 0 0 1 1 1 0 Fez1 AAA_29 PF13555.6 EON30583.1 - 0.037 13.8 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NYD-SP28 PF14772.6 EON30583.1 - 0.037 14.1 9.2 0.085 12.9 9.2 1.6 1 0 0 1 1 1 0 Sperm tail Mod_r PF07200.13 EON30583.1 - 0.043 13.9 2.5 0.13 12.4 2.5 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AAA_19 PF13245.6 EON30583.1 - 0.048 14.0 0.5 1.7 9.0 0.2 3.3 3 1 0 3 3 3 0 AAA domain HOOK PF05622.12 EON30583.1 - 0.052 11.7 7.8 0.08 11.1 7.8 1.2 1 0 0 1 1 1 0 HOOK protein NTPase_1 PF03266.15 EON30583.1 - 0.057 13.3 0.0 7.6 6.4 0.0 2.7 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 EON30583.1 - 0.062 12.5 0.0 3.4 6.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) FTA4 PF13093.6 EON30583.1 - 0.086 12.7 1.4 0.15 12.0 1.4 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Torsin PF06309.11 EON30583.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 1 0 Torsin SRP54 PF00448.22 EON30583.1 - 0.091 12.4 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 EON30583.1 - 0.098 12.7 3.3 11 6.1 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_21 PF13304.6 EON30583.1 - 0.12 12.2 0.0 37 4.0 0.0 3.6 5 0 0 5 5 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 EON30583.1 - 0.12 11.3 6.4 0.22 10.4 6.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EON30583.1 - 0.14 11.5 2.9 0.32 10.3 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_pol3_delta2 PF13177.6 EON30583.1 - 0.16 11.8 0.0 1.4 8.6 0.0 2.4 3 0 0 3 3 2 0 DNA polymerase III, delta subunit PduV-EutP PF10662.9 EON30583.1 - 0.17 11.6 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADIP PF11559.8 EON30583.1 - 0.22 11.6 5.2 0.62 10.1 5.2 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 EON30583.1 - 0.3 11.2 4.2 0.59 10.2 4.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 EON30583.1 - 0.43 11.0 11.3 1.5 9.4 1.1 3.6 2 1 1 3 3 3 0 Cell division protein ZapB Lant_dehydr_C PF14028.6 EON30583.1 - 3.6 7.0 6.7 0.8 9.2 2.1 2.2 2 1 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term APG6_N PF17675.1 EON30583.1 - 4.2 7.9 10.9 12 6.4 10.9 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region G6PD_C PF02781.16 EON30584.1 - 1.2e-72 244.5 0.0 1.5e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EON30584.1 - 3.6e-45 154.8 0.0 4.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glyco_hydro_15 PF00723.21 EON30585.1 - 3.3e-46 158.0 0.1 2.2e-42 145.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 p450 PF00067.22 EON30586.1 - 1.3e-26 93.4 0.0 4.2e-24 85.1 0.0 3.0 1 1 0 1 1 1 1 Cytochrome P450 ParE_toxin PF05016.15 EON30586.1 - 0.059 14.0 0.3 58 4.4 0.0 3.4 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE TerD PF02342.18 EON30587.1 - 4.5e-21 75.2 0.0 6.4e-19 68.2 0.0 2.7 2 1 0 2 2 2 2 TerD domain NTP_transf_9 PF04248.12 EON30588.1 - 1.6e-36 124.1 0.1 2.4e-31 107.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF2070 PF09843.9 EON30589.1 - 0.13 10.5 6.9 0.17 10.2 6.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EBP PF05241.12 EON30589.1 - 1.5 8.3 4.5 2.9 7.3 4.5 1.4 1 1 0 1 1 1 0 Emopamil binding protein Lactamase_B PF00753.27 EON30590.1 - 9.3e-06 25.8 16.1 5.6e-05 23.2 16.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON30590.1 - 1.6e-05 24.6 4.0 2.8e-05 23.7 4.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EON30590.1 - 0.00011 22.2 1.4 0.00029 20.8 1.4 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CHAD PF05235.14 EON30591.1 - 7e-43 147.2 16.9 1e-42 146.7 16.9 1.2 1 0 0 1 1 1 1 CHAD domain CYTH PF01928.21 EON30591.1 - 7.4e-05 22.7 0.6 0.00044 20.2 0.0 2.3 2 1 0 2 2 2 1 CYTH domain HemY_N PF07219.13 EON30591.1 - 0.038 14.2 1.6 0.1 12.8 1.6 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Mur_ligase_M PF08245.12 EON30592.1 - 5.5e-42 143.9 0.0 7.8e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EON30592.1 - 5.8e-15 55.3 0.0 7.2e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EON30592.1 - 1.1e-06 28.8 0.0 3.5e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, catalytic domain LpxD PF04613.14 EON30592.1 - 0.08 12.7 1.6 2.6 7.9 0.0 3.1 2 1 1 3 3 3 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Ferritin PF00210.24 EON30593.1 - 1e-05 25.5 1.8 2.3e-05 24.4 1.8 1.6 1 0 0 1 1 1 1 Ferritin-like domain UreE_N PF02814.15 EON30593.1 - 0.0057 16.2 0.8 0.016 14.8 0.1 2.1 2 0 0 2 2 2 1 UreE urease accessory protein, N-terminal domain DUF1515 PF07439.11 EON30593.1 - 0.078 13.0 1.6 0.2 11.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) MnmE_helical PF12631.7 EON30593.1 - 0.8 9.8 3.6 6.9 6.8 0.0 2.3 2 0 0 2 2 2 0 MnmE helical domain Apolipoprotein PF01442.18 EON30593.1 - 1.3 8.9 19.2 1.1 9.1 8.1 2.6 2 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain FUR PF01475.19 EON30594.1 - 9e-22 77.5 0.0 1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 EON30594.1 - 0.00071 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Nudix_N_2 PF14803.6 EON30594.1 - 0.02 14.8 0.2 0.02 14.8 0.2 2.0 2 0 0 2 2 2 0 Nudix N-terminal MarR_2 PF12802.7 EON30594.1 - 0.051 13.5 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 MarR family Penicillinase_R PF03965.16 EON30594.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor HxlR PF01638.17 EON30594.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Rubredoxin_2 PF18073.1 EON30594.1 - 0.21 11.4 3.4 2.7 7.8 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain peroxidase PF00141.23 EON30595.1 - 1.1e-80 270.6 0.0 3.8e-43 147.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 EON30595.1 - 0.02 15.1 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EON30595.1 - 0.08 13.2 0.0 6 7.2 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.28 EON30596.1 - 1e-68 231.9 0.0 1.5e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EON30596.1 - 1.7e-26 92.9 0.0 2e-11 43.2 0.0 3.9 2 2 0 2 2 2 2 Condensation domain AMP-binding_C PF13193.6 EON30596.1 - 2.4e-09 38.0 0.1 1.1e-07 32.7 0.0 3.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EON30596.1 - 4.3e-06 27.0 0.2 1.4e-05 25.4 0.2 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site WES_acyltransf PF03007.16 EON30596.1 - 0.015 15.1 6.2 1.2 8.8 0.1 3.0 2 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Esterase PF00756.20 EON30597.1 - 3.5e-30 105.5 0.6 5.3e-30 104.9 0.6 1.3 1 0 0 1 1 1 1 Putative esterase Cupin_2 PF07883.11 EON30598.1 - 9e-08 31.7 0.3 1.3e-07 31.3 0.3 1.2 1 0 0 1 1 1 1 Cupin domain TGT PF01702.18 EON30599.1 - 1.9e-109 366.0 0.0 4.2e-108 361.6 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase TipAS PF07739.13 EON30601.1 - 6.1e-40 136.4 3.1 1.1e-39 135.6 3.1 1.4 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain MerR_1 PF13411.6 EON30601.1 - 1.6e-15 57.0 0.0 2.2e-14 53.3 0.0 2.5 3 0 0 3 3 3 1 MerR HTH family regulatory protein MerR PF00376.23 EON30601.1 - 6.4e-14 51.4 0.1 1.2e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EON30601.1 - 1.7e-09 38.1 1.5 1.7e-09 38.1 1.5 2.8 2 1 1 3 3 3 1 MerR, DNA binding HTH_23 PF13384.6 EON30601.1 - 0.0058 16.4 0.1 0.53 10.2 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain Peptidase_C14 PF00656.22 EON30601.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Caspase domain MscS_porin PF12795.7 EON30601.1 - 0.43 10.1 4.7 0.24 10.9 0.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pyridoxal_deC PF00282.19 EON30602.1 - 8.3e-69 232.1 0.0 1.1e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EON30602.1 - 4.5e-05 22.6 0.0 7.9e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Mur_ligase_M PF08245.12 EON30603.1 - 2.5e-42 145.1 0.0 3.7e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EON30603.1 - 1.4e-16 60.5 0.1 8.7e-16 58.0 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EON30603.1 - 9.9e-06 25.8 1.1 0.00014 22.2 0.1 3.0 2 1 1 3 3 3 1 Mur ligase family, catalytic domain Fimbrial_K88 PF02432.15 EON30603.1 - 0.048 13.6 0.6 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Fimbrial, major and minor subunit Dala_Dala_lig_C PF07478.13 EON30604.1 - 5.6e-69 231.8 0.0 7.1e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EON30604.1 - 2.6e-26 92.1 0.0 4.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 EON30604.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EON30604.1 - 2.8e-06 27.0 0.0 4.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EON30604.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 EON30604.1 - 0.0011 18.6 0.2 0.0066 16.0 0.2 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EON30604.1 - 0.015 15.3 0.0 0.08 13.0 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain DUF4089 PF13318.6 EON30604.1 - 0.044 14.2 0.0 0.044 14.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4089) Oxidored_q4 PF00507.19 EON30606.1 - 5.3e-33 113.1 4.2 2.4e-32 111.1 4.2 1.8 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4282 PF14110.6 EON30606.1 - 0.35 11.6 6.7 4.3 8.1 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) 2TM PF13239.6 EON30606.1 - 1.3 9.4 5.7 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 2TM domain Oxidored_q6 PF01058.22 EON30607.1 - 3.1e-25 88.5 0.1 4.1e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.19 EON30608.1 - 3.5e-38 131.0 0.0 4.5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_49kDa PF00346.19 EON30609.1 - 3.6e-111 370.6 0.0 4.5e-111 370.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_51K PF01512.17 EON30610.1 - 1.7e-47 161.1 0.0 2.6e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit 2Fe-2S_thioredx PF01257.19 EON30610.1 - 2.5e-47 160.4 0.0 4e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NADH_4Fe-4S PF10589.9 EON30610.1 - 2.1e-29 101.4 0.0 5e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EON30610.1 - 3.3e-08 33.3 0.0 8.5e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DOT1 PF08123.13 EON30610.1 - 0.039 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Molybdopterin PF00384.22 EON30611.1 - 9e-20 71.0 0.0 1.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EON30611.1 - 3.4e-19 68.7 1.1 1.5e-18 66.6 0.3 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EON30611.1 - 1.1e-16 60.1 0.2 2.4e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EON30611.1 - 1.1e-06 28.4 0.4 1.1e-06 28.4 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molydop_binding PF01568.21 EON30611.1 - 4.6e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EON30611.1 - 0.0004 20.3 0.2 0.0011 18.9 0.2 1.8 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4 PF00037.27 EON30611.1 - 0.038 13.8 1.3 4 7.4 0.2 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 EON30611.1 - 1.8 9.3 6.5 8.8 7.0 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain NADHdh PF00146.21 EON30612.1 - 3.1e-125 417.4 20.5 3.7e-125 417.2 20.5 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.27 EON30613.1 - 1.8e-17 62.4 12.0 1.5e-09 37.2 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EON30613.1 - 1.9e-15 57.2 15.9 1.2e-11 45.0 6.9 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EON30613.1 - 4.6e-12 45.9 16.5 7.5e-09 35.6 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EON30613.1 - 1.1e-11 45.5 2.4 7e-06 26.9 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 EON30613.1 - 2.7e-11 42.8 10.7 3.1e-06 26.9 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EON30613.1 - 5.7e-11 42.0 12.2 1.5e-05 24.9 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EON30613.1 - 9.5e-10 38.5 18.1 9.3e-08 32.1 9.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EON30613.1 - 1.5e-09 38.2 0.8 0.00056 20.3 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EON30613.1 - 1.5e-09 37.9 19.4 4.4e-07 29.9 10.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EON30613.1 - 1.6e-08 34.9 4.1 0.0021 18.5 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON30613.1 - 6.4e-08 32.5 7.9 0.0013 19.0 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 EON30613.1 - 2.4e-06 28.1 15.9 0.001 19.9 3.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 EON30613.1 - 4.1e-06 27.6 1.7 0.027 15.3 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EON30613.1 - 1.7e-05 25.3 8.6 0.028 15.0 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EON30613.1 - 4.9e-05 23.5 2.0 0.2 11.8 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EON30613.1 - 0.012 16.3 11.6 0.039 14.7 0.2 3.0 2 1 1 3 3 3 0 4Fe-4S single cluster domain AFP PF02420.15 EON30613.1 - 1.2 9.7 9.1 15 6.3 3.4 2.5 2 0 0 2 2 2 0 Insect antifreeze protein repeat Oxidored_q3 PF00499.20 EON30614.1 - 1.1e-30 106.2 21.3 1.4e-30 105.9 21.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Oxidored_q2 PF00420.24 EON30615.1 - 1e-23 83.0 7.7 1.1e-23 82.9 7.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NAD4L PF06235.11 EON30615.1 - 0.19 11.8 5.3 0.3 11.1 5.3 1.4 1 1 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Gram_pos_anchor PF00746.21 EON30615.1 - 0.27 11.2 1.8 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PEP-CTERM PF07589.11 EON30615.1 - 7.6 6.8 6.6 1.3 9.2 0.9 2.4 2 1 0 2 2 2 0 PEP-CTERM motif Proton_antipo_M PF00361.20 EON30616.1 - 9.3e-85 284.4 11.4 2.3e-84 283.1 11.4 1.7 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 EON30616.1 - 8.9e-26 89.7 1.0 3.8e-25 87.7 0.1 2.6 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q5_N PF01059.17 EON30616.1 - 0.013 15.6 0.2 0.048 13.8 0.2 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 EON30617.1 - 4.4e-62 209.9 22.2 4.4e-62 209.9 22.2 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter CrgA PF06781.12 EON30617.1 - 0.096 12.8 2.9 0.3 11.2 0.4 3.1 2 0 0 2 2 2 0 Cell division protein CrgA Proton_antipo_M PF00361.20 EON30618.1 - 4.3e-69 233.0 13.7 2e-68 230.8 13.7 1.9 1 1 0 1 1 1 1 Proton-conducting membrane transporter UPF0715 PF17094.5 EON30618.1 - 0.061 13.9 0.6 0.061 13.9 0.6 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) SurA_N_3 PF13624.6 EON30619.1 - 0.018 14.9 2.2 3.8 7.3 0.0 3.0 2 1 1 3 3 3 0 SurA N-terminal domain Gly-zipper_YMGG PF13441.6 EON30619.1 - 3.3 7.5 32.4 11 5.9 32.4 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper Lpp-LpqN PF10738.9 EON30620.1 - 2.3e-07 30.5 0.0 3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Probable lipoprotein LpqN DUF779 PF05610.11 EON30622.1 - 7.5e-43 144.7 0.0 9e-43 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF779) Aldedh PF00171.22 EON30623.1 - 1.2e-161 538.3 0.0 1.4e-161 538.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PsbH PF00737.20 EON30623.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein GAF PF01590.26 EON30624.1 - 0.00042 20.9 1.1 0.001 19.7 0.4 2.0 2 0 0 2 2 2 1 GAF domain Trans_reg_C PF00486.28 EON30624.1 - 0.18 11.9 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal HTH_18 PF12833.7 EON30625.1 - 6.7e-20 71.2 3.3 6.7e-20 71.2 3.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON30625.1 - 1.3e-11 44.3 0.1 2e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 EON30625.1 - 0.16 12.1 2.3 0.2 11.8 0.2 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain MDMPI_N PF11716.8 EON30626.1 - 3.6e-10 40.7 10.5 6.2e-09 36.7 7.1 2.7 1 1 1 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON30626.1 - 0.028 14.9 0.3 0.053 14.0 0.3 1.6 1 1 0 1 1 1 0 DinB superfamily YccF PF03733.13 EON30628.1 - 1.5e-36 124.8 32.6 3.5e-20 72.4 14.5 2.1 2 0 0 2 2 2 2 Inner membrane component domain UL40 PF10682.9 EON30628.1 - 0.42 10.2 2.5 0.5 10.0 2.5 1.1 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 DUF2628 PF10947.8 EON30628.1 - 1.6 9.2 16.0 3.9 7.9 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) Amino_oxidase PF01593.24 EON30629.1 - 8.8e-25 87.9 2.0 1.6e-21 77.2 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EON30629.1 - 8.2e-12 45.2 0.2 4.8e-11 42.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON30629.1 - 2e-09 37.5 6.2 3.1e-08 33.6 6.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON30629.1 - 0.0015 17.7 1.3 0.0028 16.8 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON30629.1 - 0.0016 17.7 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON30629.1 - 0.024 13.9 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EON30629.1 - 0.038 13.3 0.2 0.065 12.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EON30629.1 - 0.043 12.5 0.2 0.062 12.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EON30629.1 - 0.074 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON30629.1 - 0.084 12.1 0.2 0.13 11.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EON30629.1 - 0.19 11.7 0.8 2.5 8.1 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EON30629.1 - 0.2 12.3 1.3 0.44 11.1 0.1 2.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1365 PF07103.11 EON30630.1 - 1.7e-62 211.2 0.0 1.9e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.20 EON30631.1 - 1.7e-86 289.9 0.0 2.6e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EON30631.1 - 3.1e-12 47.0 0.0 5.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON30631.1 - 3.4e-12 46.8 0.0 6.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON30631.1 - 1e-11 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30631.1 - 1.9e-07 31.7 0.0 3.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON30631.1 - 5e-05 23.1 0.0 7.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EON30631.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MTS PF05175.14 EON30631.1 - 0.15 11.6 0.0 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain DUF1295 PF06966.12 EON30632.1 - 7.2e-72 241.7 1.3 9.2e-72 241.4 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EON30632.1 - 1.5e-07 31.5 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EON30632.1 - 3.9e-07 30.4 0.5 3.9e-07 30.4 0.5 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 EON30632.1 - 0.00028 21.3 0.3 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RskA PF10099.9 EON30633.1 - 1e-26 94.3 26.4 1e-26 94.3 26.4 2.4 2 1 0 2 2 2 1 Anti-sigma-K factor rskA UCR_Fe-S_N PF10399.9 EON30633.1 - 0.012 14.9 2.0 0.029 13.7 2.0 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pex14_N PF04695.13 EON30633.1 - 0.019 15.6 3.3 0.035 14.8 3.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CwsA PF10814.8 EON30633.1 - 0.079 13.1 0.5 0.079 13.1 0.5 2.3 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA DNA_ligase_A_M PF01068.21 EON30634.1 - 3.5e-38 131.3 0.0 5.1e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EON30634.1 - 8e-14 52.0 0.1 1.8e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 EON30634.1 - 9.7e-13 48.8 0.0 2.5e-08 34.4 0.0 3.0 2 1 1 3 3 3 2 DNA ligase N terminus RNA_ligase PF09414.10 EON30634.1 - 0.008 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DUF1254 PF06863.12 EON30635.1 - 8.9e-29 100.2 0.4 2.1e-28 99.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 EON30635.1 - 6.7e-28 97.3 0.0 1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) Sulfate_transp PF00916.20 EON30636.1 - 5.6e-91 305.1 21.0 5.6e-91 305.1 21.0 1.8 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 EON30636.1 - 4.2e-14 52.2 0.0 7.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EON30636.1 - 0.0049 17.2 0.2 0.0049 17.2 0.2 2.7 2 0 0 2 2 2 1 STAS domain MFS_1 PF07690.16 EON30637.1 - 1.9e-33 115.9 77.0 2e-24 86.2 45.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON30637.1 - 6.8e-31 107.6 32.5 5.1e-29 101.4 32.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter ABC2_membrane_5 PF13346.6 EON30637.1 - 0.008 15.7 9.3 0.008 15.7 9.3 3.4 4 0 0 4 4 4 2 ABC-2 family transporter protein Lipase_GDSL_2 PF13472.6 EON30638.1 - 5.8e-21 75.7 0.4 8.1e-21 75.2 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON30638.1 - 1.6e-08 34.8 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lactamase_B PF00753.27 EON30640.1 - 3.1e-25 89.3 7.7 4.1e-25 88.9 7.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON30640.1 - 1.2e-06 28.2 1.0 2.2e-06 27.3 0.8 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EON30640.1 - 0.00047 20.1 0.5 0.00068 19.6 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ADH_zinc_N PF00107.26 EON30641.1 - 4.9e-28 97.7 0.0 9.3e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON30641.1 - 1.3e-26 92.6 1.0 1.3e-26 92.6 1.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EON30641.1 - 6.4e-10 40.2 0.0 1.2e-09 39.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON30641.1 - 2.1e-09 37.2 1.0 5.9e-07 29.2 1.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 EON30641.1 - 0.0023 18.2 0.4 0.0051 17.1 0.4 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EON30641.1 - 0.0064 16.7 1.4 0.0098 16.2 0.4 1.8 2 1 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 EON30641.1 - 0.0094 16.5 0.6 0.028 15.0 0.6 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EON30641.1 - 0.023 14.0 4.3 0.054 12.8 4.3 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EON30641.1 - 0.26 11.1 1.7 0.74 9.7 1.7 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rho_N PF07498.12 EON30642.1 - 3.1e-07 30.2 0.1 5.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 EON30642.1 - 0.00016 21.4 2.0 0.041 13.6 0.0 2.5 3 0 0 3 3 3 2 SAP domain Ish1 PF10281.9 EON30642.1 - 0.13 12.6 7.3 0.75 10.2 3.2 3.1 2 1 0 2 2 2 0 Putative stress-responsive nuclear envelope protein GerE PF00196.19 EON30644.1 - 1.2e-12 47.2 0.0 2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family GAF_2 PF13185.6 EON30644.1 - 1e-07 32.4 0.1 1.9e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 GAF domain Sigma70_r4_2 PF08281.12 EON30644.1 - 1.7e-05 24.4 0.3 3.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 GAF PF01590.26 EON30644.1 - 2.3e-05 25.1 0.0 4.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain Sigma70_r4 PF04545.16 EON30644.1 - 3.4e-05 23.3 0.0 0.00019 20.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 EON30644.1 - 0.0058 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain AMP-binding PF00501.28 EON30645.1 - 7.6e-72 242.2 0.0 9.9e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30645.1 - 1.4e-26 93.3 0.9 2e-24 86.3 0.5 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Pyridox_ox_2 PF12900.7 EON30646.1 - 2.7e-33 114.9 0.1 3.8e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EON30646.1 - 6.7e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MTES_1575 PF18741.1 EON30647.1 - 2.5e-06 27.6 0.1 8.5e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 REase_MTES_1575 DUF559 PF04480.12 EON30647.1 - 0.00027 20.8 0.0 0.0079 16.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF559) AbiEi_4 PF13338.6 EON30647.1 - 0.067 13.3 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Glyoxalase PF00903.25 EON30648.1 - 1.4e-06 28.5 0.1 2.1e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON30648.1 - 0.00098 19.9 0.2 0.0014 19.4 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Acetyltransf_10 PF13673.7 EON30648.1 - 0.0016 18.3 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.7 EON30648.1 - 0.017 15.1 0.0 0.073 13.0 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EON30648.1 - 0.059 13.5 0.1 2.8 8.0 0.1 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain Glutaminase PF04960.15 EON30649.1 - 6.4e-107 357.0 0.0 7.6e-107 356.7 0.0 1.0 1 0 0 1 1 1 1 Glutaminase STAS_2 PF13466.6 EON30649.1 - 0.0041 17.4 1.4 0.0041 17.4 1.4 2.3 3 0 0 3 3 3 1 STAS domain STAS PF01740.21 EON30649.1 - 0.034 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 STAS domain Arabinose_bd PF12625.7 EON30650.1 - 3.4e-34 118.5 3.0 3.4e-34 118.5 3.0 1.7 2 1 0 2 2 2 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 EON30650.1 - 1.4e-12 47.7 0.1 4.1e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EON30650.1 - 0.0094 16.1 0.6 0.13 12.4 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON30650.1 - 0.029 14.5 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Clp_N PF02861.20 EON30650.1 - 0.045 13.9 0.3 0.72 10.0 0.0 2.7 2 1 1 3 3 3 0 Clp amino terminal domain, pathogenicity island component HTH_38 PF13936.6 EON30650.1 - 0.12 12.2 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EON30650.1 - 0.19 11.6 0.7 1.9 8.4 0.0 2.9 4 0 0 4 4 4 0 Homeodomain-like domain Aldedh PF00171.22 EON30651.1 - 2.8e-156 520.7 0.0 3.1e-156 520.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Inhibitor_I48 PF10467.9 EON30651.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Semialdhyde_dh PF01118.24 EON30651.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MDMPI_N PF11716.8 EON30652.1 - 1.8e-09 38.4 3.7 1.8e-09 38.4 3.7 1.8 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON30652.1 - 0.00018 22.0 1.1 0.00037 21.0 1.1 1.5 1 0 0 1 1 1 1 DinB superfamily MDMPI_C PF07398.11 EON30652.1 - 0.0093 16.8 6.0 0.025 15.4 6.0 1.8 1 0 0 1 1 1 1 MDMPI C-terminal domain adh_short PF00106.25 EON30653.1 - 8.5e-47 159.1 12.3 1.2e-46 158.7 12.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON30653.1 - 1.6e-32 112.9 13.0 2.2e-32 112.5 13.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON30653.1 - 3.7e-07 30.2 6.4 9.7e-07 28.9 6.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EON30653.1 - 0.0011 18.4 5.7 0.0032 16.9 5.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EON30653.1 - 0.0082 16.8 0.3 0.016 15.9 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EON30653.1 - 0.039 13.3 0.7 0.083 12.2 0.7 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EON30653.1 - 0.14 12.0 3.7 0.26 11.2 3.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 EON30654.1 - 2.4e-68 230.7 0.1 2.9e-68 230.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30654.1 - 2.8e-20 73.1 0.0 5.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EON30654.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Prot_ATP_ID_OB PF16450.5 EON30654.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Abhydrolase_3 PF07859.13 EON30655.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EON30655.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 EON30655.1 - 0.047 12.6 0.0 0.21 10.5 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 EON30655.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RNA_pol_Rpb1_1 PF04997.12 EON30656.1 - 5.9e-82 275.5 0.0 8.8e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EON30656.1 - 2.3e-64 217.4 2.7 5.2e-64 216.3 2.7 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EON30656.1 - 7.2e-39 133.7 0.0 3.8e-28 98.8 0.0 2.6 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EON30656.1 - 6.9e-27 94.3 0.0 1.4e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EON30656.1 - 5e-07 29.6 0.0 2e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb2_6 PF00562.28 EON30657.1 - 4.6e-159 529.6 0.0 1.8e-158 527.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EON30657.1 - 2e-29 101.6 0.0 3.8e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EON30657.1 - 2.5e-27 95.8 0.0 1.5e-23 83.4 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EON30657.1 - 3.6e-27 94.6 0.0 7.4e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 EON30657.1 - 1.4e-23 82.9 0.5 1.3e-22 79.8 0.9 2.5 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_1 PF04563.15 EON30657.1 - 5.2e-23 81.6 0.0 1.7e-22 80.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit Robl_LC7 PF03259.17 EON30657.1 - 0.14 12.0 0.1 0.42 10.4 0.1 1.8 1 0 0 1 1 1 0 Roadblock/LC7 domain 7TMR-HDED PF07697.11 EON30658.1 - 0.0089 16.2 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 7TM-HD extracellular SPX PF03105.19 EON30658.1 - 0.49 10.3 3.4 0.65 9.9 3.4 1.1 1 0 0 1 1 1 0 SPX domain UCR_Fe-S_N PF10399.9 EON30658.1 - 3 7.3 7.8 0.21 11.0 2.3 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal RskA PF10099.9 EON30659.1 - 0.013 15.9 6.2 0.042 14.1 6.2 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA MlaD PF02470.20 EON30660.1 - 7.7e-16 58.2 0.1 1.7e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30660.1 - 2.1e-07 30.7 1.8 2.9e-07 30.2 1.8 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative OSCP PF00213.18 EON30660.1 - 0.044 13.9 0.1 0.2 11.8 0.1 1.9 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit MlaD PF02470.20 EON30661.1 - 5.5e-16 58.6 0.1 9.7e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30661.1 - 1.8e-09 37.5 3.9 3.3e-09 36.6 3.4 1.8 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 EON30661.1 - 0.0054 17.0 0.2 0.018 15.3 0.2 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 EON30661.1 - 0.016 13.4 0.0 0.021 13.0 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 EON30661.1 - 0.039 14.0 4.8 1.7 8.6 0.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MreC PF04085.14 EON30661.1 - 0.075 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 rod shape-determining protein MreC BLOC1_2 PF10046.9 EON30661.1 - 0.089 13.1 0.0 1 9.7 0.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LXG PF04740.12 EON30661.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily SlyX PF04102.12 EON30661.1 - 2.4 8.8 5.0 14 6.4 0.2 3.1 2 1 1 3 3 3 0 SlyX NPV_P10 PF05531.12 EON30661.1 - 9.5 6.8 8.6 45 4.6 3.2 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MlaD PF02470.20 EON30662.1 - 7.6e-13 48.6 1.5 1.6e-12 47.6 1.5 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30662.1 - 3e-07 30.2 4.8 4.5e-07 29.6 4.8 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 EON30662.1 - 0.022 14.8 10.0 0.47 10.5 5.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EON30662.1 - 0.027 12.4 0.1 0.04 11.9 0.1 1.2 1 0 0 1 1 1 0 Prominin Mating_N PF12731.7 EON30662.1 - 0.096 12.8 0.3 0.24 11.5 0.2 1.8 1 1 0 1 1 1 0 Mating-type protein beta 1 Phage_holin_3_5 PF16085.5 EON30662.1 - 0.097 12.8 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III DUF1664 PF07889.12 EON30662.1 - 0.11 12.5 0.1 2.5 8.2 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BAR_3 PF16746.5 EON30662.1 - 0.13 12.0 0.2 0.8 9.4 0.6 1.9 2 0 0 2 2 2 0 BAR domain of APPL family DUF2205 PF10224.9 EON30662.1 - 0.13 12.3 0.4 10 6.2 0.1 2.8 1 1 1 2 2 2 0 Short coiled-coil protein HsbA PF12296.8 EON30662.1 - 0.24 11.8 4.6 0.15 12.5 1.5 2.3 3 0 0 3 3 3 0 Hydrophobic surface binding protein A DUF1467 PF07330.12 EON30662.1 - 0.5 10.3 2.4 0.68 9.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) CorA PF01544.18 EON30662.1 - 1.2 8.3 5.2 0.75 9.1 0.1 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein MlaD PF02470.20 EON30663.1 - 4.3e-18 65.4 0.1 7.6e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON30663.1 - 1.6e-07 31.1 0.5 2.2e-07 30.6 0.5 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 EON30663.1 - 0.17 12.2 0.1 10 6.5 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MlaD PF02470.20 EON30664.1 - 5e-14 52.3 0.1 1.1e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 MlaD protein EzrA PF06160.12 EON30664.1 - 9.1e-06 24.1 0.0 1.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PhaP_Bmeg PF09602.10 EON30664.1 - 0.0042 17.0 0.1 0.0059 16.6 0.1 1.2 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Baculo_PEP_C PF04513.12 EON30664.1 - 0.0047 17.0 12.1 0.023 14.7 9.5 2.4 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Mce4_CUP1 PF11887.8 EON30664.1 - 0.0075 15.8 3.7 0.016 14.6 3.7 1.5 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative PKcGMP_CC PF16808.5 EON30664.1 - 0.0098 15.7 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 EON30664.1 - 0.15 12.1 0.6 11 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EON30664.1 - 0.93 9.8 5.0 6.5 7.1 3.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Mce4_CUP1 PF11887.8 EON30665.1 - 3e-54 184.2 0.0 3.9e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 EON30665.1 - 4.5e-11 42.9 0.1 8.1e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 MlaD protein Baculo_PEP_C PF04513.12 EON30665.1 - 0.0087 16.1 1.0 0.02 14.9 0.7 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EON30665.1 - 0.013 15.8 0.9 1.6 9.0 0.0 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Utp12 PF04003.12 EON30665.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family GBP_repeat PF02526.14 EON30665.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycophorin-binding protein MlaE PF02405.16 EON30666.1 - 1.1e-60 204.9 20.3 1.5e-60 204.5 20.3 1.1 1 0 0 1 1 1 1 Permease MlaE DPM3 PF08285.11 EON30666.1 - 0.23 11.7 0.2 0.23 11.7 0.2 2.2 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MlaE PF02405.16 EON30667.1 - 2e-66 223.7 18.7 2.5e-66 223.4 18.7 1.1 1 0 0 1 1 1 1 Permease MlaE LMWPc PF01451.21 EON30670.1 - 9.8e-21 74.6 0.0 1.4e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LMWPc PF01451.21 EON30671.1 - 4e-14 53.2 0.0 5.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LMWPc PF01451.21 EON30672.1 - 1.8e-13 51.1 0.0 6.5e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyoxalase PF00903.25 EON30673.1 - 1e-07 32.2 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON30673.1 - 0.00044 20.5 0.0 0.065 13.5 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON30673.1 - 0.0023 18.7 0.0 0.0038 18.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain FAM124 PF15067.6 EON30673.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 FAM124 family HTH_5 PF01022.20 EON30674.1 - 1.6e-12 47.1 0.0 2.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON30674.1 - 1.2e-11 44.5 0.8 2e-11 43.8 0.3 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain FaeA PF04703.12 EON30674.1 - 0.00028 21.2 0.0 0.00041 20.7 0.0 1.2 1 0 0 1 1 1 1 FaeA-like protein HTH_Crp_2 PF13545.6 EON30674.1 - 0.00028 20.8 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EON30674.1 - 0.00074 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 EON30674.1 - 0.015 15.5 0.0 0.042 14.0 0.0 1.7 1 1 1 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.19 EON30674.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EON30674.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain PaaX PF07848.12 EON30674.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Methyltransf_11 PF08241.12 EON30675.1 - 6.6e-23 81.2 0.0 9.4e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON30675.1 - 2e-21 76.5 0.1 3e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30675.1 - 3.7e-16 59.7 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON30675.1 - 6.2e-16 58.7 0.0 7.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON30675.1 - 2.2e-12 46.8 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EON30675.1 - 3.5e-12 46.4 0.0 4.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON30675.1 - 6e-06 25.9 0.0 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EON30675.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 EON30675.1 - 0.00097 18.5 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EON30675.1 - 0.0013 18.3 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 EON30675.1 - 0.016 14.5 0.1 0.036 13.4 0.1 1.5 1 1 1 2 2 2 0 O-methyltransferase domain UPF0020 PF01170.18 EON30675.1 - 0.029 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 EON30675.1 - 0.036 13.6 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EON30675.1 - 0.18 10.8 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 EON30675.1 - 0.21 11.2 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 EON30675.1 - 0.25 10.5 0.0 1.4 8.0 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family HTH_5 PF01022.20 EON30676.1 - 5.3e-12 45.4 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON30676.1 - 1.1e-08 35.0 2.4 1.1e-08 34.9 0.7 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EON30676.1 - 5.5e-07 29.4 0.4 8.9e-07 28.7 0.4 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EON30676.1 - 1.4e-05 24.8 0.2 3e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EON30676.1 - 0.00073 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 EON30676.1 - 0.00087 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 PaaX-like protein HTH_24 PF13412.6 EON30676.1 - 0.0088 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 EON30676.1 - 0.0094 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain RP-C PF03428.13 EON30676.1 - 0.023 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_34 PF13601.6 EON30676.1 - 0.093 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.22 EON30676.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 EON30676.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain E1-E2_ATPase PF00122.20 EON30677.1 - 1.2e-46 158.6 5.5 1.2e-46 158.6 5.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EON30677.1 - 7.7e-34 117.8 6.5 7.7e-34 117.8 6.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON30677.1 - 0.069 13.6 0.5 0.47 10.8 0.3 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON30677.1 - 0.11 12.2 0.9 0.27 10.9 0.9 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_A8 PF01252.18 EON30678.1 - 5.4e-25 88.3 1.0 6.5e-25 88.0 1.0 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II Thioredoxin_4 PF13462.6 EON30679.1 - 3.6e-20 72.8 0.0 4.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EON30679.1 - 5.3e-15 55.7 2.0 8.5e-14 51.8 1.9 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EON30679.1 - 8.5e-05 23.0 0.0 0.0002 21.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.6 EON30679.1 - 0.0028 17.4 0.0 0.024 14.3 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 EON30679.1 - 0.05 13.6 0.0 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 EON30679.1 - 0.06 13.2 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein DEDD_Tnp_IS110 PF01548.17 EON30680.1 - 4.9e-40 136.9 0.7 1.3e-39 135.6 0.0 2.0 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 EON30680.1 - 5e-23 81.2 0.1 1.1e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family Big_10 PF17964.1 EON30681.1 - 1.3e-38 132.8 0.1 2.3e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 EON30681.1 - 1.7e-18 67.5 0.2 2.6e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain BNR PF02012.20 EON30683.1 - 0.0012 18.5 7.9 0.29 11.3 0.0 3.7 4 0 0 4 4 4 2 BNR/Asp-box repeat PSII_BNR PF14870.6 EON30683.1 - 0.009 15.3 1.6 0.13 11.5 0.3 2.5 1 1 1 2 2 2 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 EON30683.1 - 0.19 10.5 0.1 0.85 8.3 0.0 1.9 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, Peptidase_M48 PF01435.18 EON30685.1 - 1.2e-08 35.0 0.1 4.5e-08 33.1 0.1 1.7 1 1 1 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EON30685.1 - 0.046 12.9 0.1 0.085 12.0 0.1 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF305 PF03713.13 EON30686.1 - 2e-52 177.3 18.4 2.8e-52 176.9 18.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 EON30686.1 - 2.4e-11 44.0 6.3 7.1e-07 29.6 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4142) Snf7 PF03357.21 EON30686.1 - 0.0015 18.2 3.1 0.003 17.2 0.3 2.1 1 1 1 2 2 2 1 Snf7 Fis1_TPR_C PF14853.6 EON30686.1 - 0.24 11.5 0.1 0.24 11.5 0.1 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_M23 PF01551.22 EON30687.1 - 1e-27 96.1 0.1 3.6e-27 94.4 0.1 2.0 1 0 0 1 1 1 1 Peptidase family M23 SseC PF04888.12 EON30687.1 - 0.013 15.1 0.3 0.015 14.9 0.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Trns_repr_metal PF02583.17 EON30688.1 - 1.9e-29 101.9 0.8 2.2e-29 101.6 0.8 1.1 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor E1-E2_ATPase PF00122.20 EON30689.1 - 1.4e-46 158.3 4.0 1.4e-46 158.3 4.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EON30689.1 - 1.7e-41 142.9 9.4 3e-41 142.0 9.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON30689.1 - 8.5e-07 29.0 0.5 0.00026 20.8 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON30689.1 - 4.7e-06 27.1 2.1 1.3e-05 25.7 0.7 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 EON30689.1 - 0.033 14.7 0.4 0.11 13.0 0.4 1.9 1 0 0 1 1 1 0 CoA binding domain Peptidase_M55 PF04951.13 EON30689.1 - 0.051 13.0 1.7 0.079 12.3 0.1 2.1 3 0 0 3 3 3 0 D-aminopeptidase CysA_C_terminal PF17850.1 EON30689.1 - 1 10.0 5.5 3.8 8.2 0.2 4.0 3 0 0 3 3 3 0 CysA C-terminal regulatory domain E1-E2_ATPase PF00122.20 EON30690.1 - 7.6e-51 172.2 4.7 7.6e-51 172.2 4.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EON30690.1 - 5.6e-44 150.9 13.6 6.3e-44 150.8 12.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EON30690.1 - 2.9e-14 53.3 0.0 8.4e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EON30690.1 - 5.1e-06 26.4 5.3 0.00014 21.7 3.4 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON30690.1 - 0.005 17.3 0.2 0.027 14.9 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EON30692.1 - 3.8e-16 59.3 0.2 4.2e-16 59.2 0.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain MFS_1 PF07690.16 EON30693.1 - 4.3e-24 85.1 61.7 2.8e-22 79.2 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON30693.1 - 0.016 14.1 23.9 0.0076 15.2 4.4 2.1 1 1 1 2 2 2 0 MFS_1 like family SLATT_5 PF18160.1 EON30693.1 - 0.058 12.7 0.3 0.15 11.3 0.3 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 T7SS_ESX_EspC PF10824.8 EON30693.1 - 0.4 11.2 3.0 1.8 9.1 0.8 2.5 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm PALP PF00291.25 EON30694.1 - 2.1e-46 158.7 0.2 2.7e-46 158.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4190 PF13828.6 EON30694.1 - 0.062 13.1 2.1 1.9 8.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Trans_reg_C PF00486.28 EON30695.1 - 2.5e-26 91.6 0.0 4.1e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EON30695.1 - 7.1e-26 90.6 0.1 1e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain MarR_2 PF12802.7 EON30695.1 - 0.018 14.9 0.1 0.11 12.4 0.0 2.5 3 0 0 3 3 3 0 MarR family HATPase_c PF02518.26 EON30696.1 - 3e-23 82.4 0.1 8.8e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON30696.1 - 9e-10 38.5 2.3 9.2e-10 38.4 0.3 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EON30696.1 - 7.1e-09 35.9 4.3 9.1e-09 35.6 0.4 2.6 2 1 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 EON30696.1 - 0.0055 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EcoEI_R_C PF08463.10 EON30696.1 - 0.084 13.0 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal A2M_BRD PF07703.14 EON30696.1 - 0.17 12.2 0.4 3.4 8.0 0.4 2.4 1 1 0 1 1 1 0 Alpha-2-macroglobulin bait region domain HATPase_c_5 PF14501.6 EON30696.1 - 0.18 11.7 0.0 0.5 10.3 0.0 1.7 1 1 0 1 1 1 0 GHKL domain Penicillinase_R PF03965.16 EON30697.1 - 2.9e-23 82.4 0.1 3.3e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 EON30697.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Glycos_transf_N PF04413.16 EON30697.1 - 0.048 13.3 0.1 0.061 13.0 0.1 1.3 1 1 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Rop-like PF05082.13 EON30697.1 - 0.06 13.2 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 Rop-like DUF488 PF04343.13 EON30697.1 - 0.083 13.5 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF488 DotU PF09850.9 EON30697.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU Gemini_mov PF01708.16 EON30698.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein Na_Ca_ex PF01699.24 EON30699.1 - 0.2 11.6 8.9 0.44 10.5 8.9 1.6 1 1 0 1 1 1 0 Sodium/calcium exchanger protein SID-1_RNA_chan PF13965.6 EON30699.1 - 0.25 9.7 0.6 0.33 9.3 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HRG PF16954.5 EON30699.1 - 5 7.6 9.2 14 6.2 4.6 3.3 2 1 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Phage_integrase PF00589.22 EON30700.1 - 2.3e-05 24.3 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Orthopox_F8 PF05886.11 EON30700.1 - 4.8 7.4 6.2 0.33 11.1 0.9 1.7 2 0 0 2 2 2 0 Orthopoxvirus F8 protein DSBA PF01323.20 EON30701.1 - 1.2e-12 48.0 0.1 9.6e-12 45.1 0.1 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain DUF2252 PF10009.9 EON30701.1 - 0.039 13.0 0.1 0.055 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF302 PF03625.14 EON30702.1 - 1.7e-22 79.0 0.2 2.7e-22 78.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 DUF2892 PF11127.8 EON30703.1 - 1.6e-07 31.3 7.4 1.7e-07 31.1 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) FAD_binding_4 PF01565.23 EON30704.1 - 1.4e-26 92.9 7.5 1.4e-26 92.9 7.5 1.6 2 0 0 2 2 2 1 FAD binding domain GerE PF00196.19 EON30705.1 - 3.1e-11 42.6 0.1 5.1e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family FaeA PF04703.12 EON30705.1 - 0.047 14.1 0.5 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 FaeA-like protein HTH_10 PF04967.12 EON30705.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain E3_UFM1_ligase PF09743.9 EON30705.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Phenol_Hydrox PF02332.18 EON30706.1 - 2.6e-57 194.0 0.0 4.4e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase NAD_binding_1 PF00175.21 EON30707.1 - 6.4e-16 59.0 0.0 1.1e-14 55.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON30707.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 EON30707.1 - 5.4e-14 51.9 1.1 1e-13 51.0 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_8 PF08022.12 EON30707.1 - 0.00092 19.3 0.1 0.0041 17.2 0.1 1.9 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EON30707.1 - 0.021 14.9 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Fer2_4 PF13510.6 EON30707.1 - 0.021 14.8 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NucS PF01939.16 EON30707.1 - 0.21 10.9 0.0 3.8 6.8 0.0 2.0 2 0 0 2 2 2 0 Endonuclease NucS Phenol_Hydrox PF02332.18 EON30708.1 - 5.7e-50 170.0 2.0 7.2e-50 169.7 2.0 1.1 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase DUF5049 PF16468.5 EON30708.1 - 0.068 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) MmoB_DmpM PF02406.17 EON30709.1 - 2e-19 69.6 0.0 2.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 MmoB/DmpM family Amidohydro_2 PF04909.14 EON30710.1 - 1.9e-38 133.0 3.5 2.4e-38 132.6 3.5 1.1 1 0 0 1 1 1 1 Amidohydrolase FeS_assembly_P PF01883.19 EON30711.1 - 1.2e-17 63.8 0.0 2.6e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ADH_N PF08240.12 EON30712.1 - 3.9e-31 107.2 0.5 3.9e-31 107.2 0.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON30712.1 - 5.1e-19 68.5 1.8 5.1e-19 68.5 1.8 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON30712.1 - 4.7e-10 40.6 1.3 6.2e-10 40.2 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ThiF PF00899.21 EON30712.1 - 0.045 13.1 0.4 0.074 12.4 0.4 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EON30712.1 - 0.086 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cpn60_TCP1 PF00118.24 EON30713.1 - 9.8e-85 285.0 10.8 1.6e-84 284.3 10.8 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_8 PF02954.19 EON30714.1 - 4.7e-11 42.3 0.4 2.1e-10 40.2 0.4 2.2 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 EON30714.1 - 8.7e-05 22.0 0.7 0.0003 20.3 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON30714.1 - 0.00059 19.6 0.1 0.0026 17.5 0.1 2.2 1 0 0 1 1 1 1 Homeodomain-like domain GAF PF01590.26 EON30714.1 - 0.0013 19.4 0.0 0.004 17.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain HTH_22 PF13309.6 EON30714.1 - 0.0015 18.6 0.1 0.0057 16.7 0.1 2.0 1 1 0 1 1 1 1 HTH domain HTH_28 PF13518.6 EON30714.1 - 0.0052 16.9 0.0 0.018 15.1 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EON30714.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 EON30714.1 - 0.024 14.6 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix AAA_16 PF13191.6 EON30714.1 - 0.072 13.5 2.1 0.1 13.0 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain HTH_30 PF13556.6 EON30714.1 - 0.073 12.9 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Phage_AlpA PF05930.12 EON30714.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.7 EON30714.1 - 0.16 12.1 0.0 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Acyl-CoA_dh_C PF12806.7 EON30715.1 - 3.5e-30 104.7 0.3 6.9e-30 103.7 0.3 1.5 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 EON30715.1 - 1.9e-16 60.6 0.0 2e-15 57.3 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON30715.1 - 5.3e-15 55.4 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_DH_N PF12418.8 EON30715.1 - 4.3e-09 36.2 0.1 9.4e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_N PF02771.16 EON30715.1 - 7.9e-08 33.0 0.0 2.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON30715.1 - 0.0083 16.4 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 EON30716.1 - 4.7e-63 212.9 2.7 5.4e-63 212.7 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON30716.1 - 5.4e-55 185.9 0.7 6.6e-55 185.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON30716.1 - 5.7e-17 62.2 1.1 8e-17 61.7 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON30716.1 - 0.00011 21.7 0.1 0.00021 20.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EON30716.1 - 0.0051 15.9 0.5 0.0096 15.1 0.5 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N PF00107.26 EON30716.1 - 0.038 14.0 1.2 0.087 12.8 1.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EON30716.1 - 0.046 13.0 0.4 0.14 11.5 0.2 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain bPH_2 PF03703.14 EON30717.1 - 4.2e-17 62.1 0.0 6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain Lenti_VIF_2 PF07401.12 EON30717.1 - 0.0046 16.3 0.1 0.006 16.0 0.1 1.1 1 0 0 1 1 1 1 Bovine Lentivirus VIF protein DUF1772 PF08592.11 EON30717.1 - 0.0068 16.7 1.3 0.0068 16.7 1.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) SLATT_1 PF18181.1 EON30717.1 - 0.035 14.0 3.6 0.035 14.0 3.6 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1440 PF07274.12 EON30717.1 - 0.037 14.4 0.1 0.049 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) DUF4231 PF14015.6 EON30717.1 - 1.4 9.4 5.9 0.35 11.4 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) bPH_2 PF03703.14 EON30718.1 - 3.5e-25 88.0 2.4 5.7e-16 58.5 0.4 3.3 3 0 0 3 3 3 3 Bacterial PH domain bPH_4 PF06713.11 EON30718.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial PH domain FA_desaturase PF00487.24 EON30718.1 - 0.011 15.6 5.7 2.9 7.6 0.3 3.2 3 0 0 3 3 3 0 Fatty acid desaturase Chromate_transp PF02417.15 EON30719.1 - 1.1e-61 207.6 51.2 2.9e-32 112.0 15.5 2.4 3 0 0 3 3 3 2 Chromate transporter DUF4731 PF15875.5 EON30719.1 - 0.081 13.1 1.0 0.32 11.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) tRNA-synt_His PF13393.6 EON30720.1 - 0.023 14.0 0.3 0.03 13.6 0.3 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase TPR_MLP1_2 PF07926.12 EON30720.1 - 0.12 12.5 1.1 0.26 11.3 1.2 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 EON30720.1 - 0.98 7.9 6.6 1.3 7.5 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Chrome_Resist PF09828.9 EON30721.1 - 3.1e-48 163.5 0.0 3.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Chromate resistance exported protein bPH_6 PF10756.9 EON30722.1 - 0.23 11.5 6.1 0.35 11.0 1.5 2.1 2 0 0 2 2 2 0 Bacterial PH domain Amino_oxidase PF01593.24 EON30723.1 - 1.2e-17 64.4 0.1 2.2e-16 60.2 0.1 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EON30723.1 - 4.3e-11 42.9 0.2 1.1e-10 41.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON30723.1 - 2.9e-08 33.3 0.0 0.0008 18.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON30723.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON30723.1 - 1.3e-05 24.5 0.5 0.00033 19.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EON30723.1 - 0.0048 16.9 0.1 0.0097 15.9 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EON30723.1 - 0.0077 15.0 0.0 0.023 13.4 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EON30723.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EON30723.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EON30723.1 - 0.023 14.0 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 EON30723.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 EON30723.1 - 0.072 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EON30723.1 - 0.11 11.6 0.4 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 EON30723.1 - 0.12 11.1 0.0 17 4.0 0.0 2.9 3 0 0 3 3 3 0 MCRA family Pyr_redox PF00070.27 EON30723.1 - 0.14 12.7 0.0 1.3 9.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON30723.1 - 0.48 9.7 1.8 0.36 10.1 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TetR_N PF00440.23 EON30724.1 - 2e-11 43.5 0.1 4.3e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family CTC1 PF15489.6 EON30724.1 - 0.25 8.8 0.1 0.31 8.5 0.1 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 TetR_C_31 PF17940.1 EON30724.1 - 1.1 9.5 9.1 0.066 13.4 1.7 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NUDIX PF00293.28 EON30725.1 - 1.8e-13 50.7 0.2 4.5e-13 49.4 0.2 1.7 1 1 0 1 1 1 1 NUDIX domain Xan_ur_permease PF00860.20 EON30726.1 - 1e-98 330.6 41.8 1.4e-98 330.2 41.8 1.1 1 0 0 1 1 1 1 Permease family TM_helix PF05552.12 EON30726.1 - 1.6 8.8 8.9 0.56 10.2 2.8 2.9 2 0 0 2 2 2 0 Conserved TM helix Cupin_2 PF07883.11 EON30727.1 - 0.042 13.6 0.9 0.071 12.8 0.4 1.8 1 1 0 1 1 1 0 Cupin domain Glyoxalase PF00903.25 EON30729.1 - 3.1e-09 37.1 0.0 3.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EON30729.1 - 5.2e-08 32.8 0.0 7.4e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EON30729.1 - 0.00019 22.2 0.3 0.00031 21.5 0.3 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain EPSP_synthase PF00275.20 EON30730.1 - 7.3e-112 374.1 0.0 8.9e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Cadherin_4 PF17803.1 EON30730.1 - 1.5 9.5 4.4 6.2 7.5 0.1 3.5 3 1 0 3 3 3 0 Bacterial cadherin-like domain RsgA_GTPase PF03193.16 EON30731.1 - 7.2e-39 133.4 0.0 9.2e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EON30731.1 - 1.5e-06 28.3 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EON30731.1 - 7.6e-06 26.4 0.3 5e-05 23.8 0.1 2.2 3 0 0 3 3 2 1 AAA ATPase domain ABC_tran PF00005.27 EON30731.1 - 0.0012 19.4 0.1 0.0019 18.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EON30731.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EON30731.1 - 0.0034 16.9 0.0 0.16 11.5 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EON30731.1 - 0.016 15.3 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON30731.1 - 0.022 15.0 0.1 0.041 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EON30731.1 - 0.033 14.4 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 EON30731.1 - 0.047 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.18 EON30731.1 - 0.05 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.22 EON30731.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ras family TPR_9 PF13371.6 EON30731.1 - 0.08 13.1 0.5 1.4 9.1 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat MobB PF03205.14 EON30731.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EON30731.1 - 0.18 12.2 0.0 0.57 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 EON30731.1 - 0.26 11.3 0.1 3.2 7.8 0.0 2.1 1 1 1 2 2 2 0 Dynamin family AIG1 PF04548.16 EON30731.1 - 0.28 10.5 0.0 0.84 8.9 0.0 1.7 2 0 0 2 2 2 0 AIG1 family FA_desaturase PF00487.24 EON30732.1 - 6.3e-27 95.0 3.7 8.2e-27 94.6 3.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF475 PF04332.15 EON30733.1 - 2.4e-132 441.2 7.0 3.8e-132 440.5 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF475) TerC PF03741.16 EON30733.1 - 8e-19 68.0 7.8 4e-16 59.2 7.8 2.8 1 1 0 1 1 1 1 Integral membrane protein TerC family TerD PF02342.18 EON30734.1 - 3.6e-85 284.2 0.0 4e-85 284.0 0.0 1.0 1 0 0 1 1 1 1 TerD domain adh_short_C2 PF13561.6 EON30735.1 - 3.3e-59 200.3 0.3 3.9e-59 200.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON30735.1 - 1.1e-41 142.4 0.8 1.4e-41 142.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON30735.1 - 1.1e-07 31.9 0.4 1.8e-07 31.2 0.4 1.3 1 0 0 1 1 1 1 KR domain TetR_N PF00440.23 EON30736.1 - 6.9e-05 22.6 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_8 PF14278.6 EON30736.1 - 8.7e-05 22.6 0.0 0.00021 21.4 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulator C-terminal region HTH_20 PF12840.7 EON30736.1 - 0.7 10.0 3.3 21 5.2 0.0 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain Inos-1-P_synth PF01658.17 EON30737.1 - 5e-32 110.4 0.1 1.9e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 EON30737.1 - 0.016 14.6 0.0 0.066 12.6 0.0 1.8 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase PadR PF03551.14 EON30738.1 - 8e-21 73.8 0.1 1.4e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 EON30738.1 - 0.033 14.9 0.5 0.063 14.0 0.5 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term AphA_like PF14557.6 EON30738.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF5318 PF17249.2 EON30739.1 - 5.4e-63 210.6 0.9 6.1e-63 210.4 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5318) Transgly PF00912.22 EON30740.1 - 3.4e-54 183.0 0.0 8.1e-54 181.8 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 EON30740.1 - 3.1e-26 92.3 1.8 4.8e-26 91.7 1.8 1.3 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain GT87 PF09594.10 EON30741.1 - 6.2e-15 55.6 42.2 6.2e-15 55.6 42.2 3.4 2 1 1 3 3 3 1 Glycosyltransferase family 87 Mannosyl_trans PF05007.13 EON30741.1 - 0.0013 18.6 9.1 0.0013 18.6 9.1 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) Acetyltransf_3 PF13302.7 EON30743.1 - 5.6e-19 69.2 0.0 7.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Prok-E2_C PF14459.6 EON30744.1 - 0.073 13.2 0.5 0.21 11.8 0.5 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family C Ribosomal_S6 PF01250.17 EON30745.1 - 3.2e-27 94.6 0.0 3.5e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 CCAP PF11105.8 EON30745.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a SSB PF00436.25 EON30746.1 - 1.1e-31 109.0 0.1 1.5e-31 108.5 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 EON30746.1 - 0.00013 21.9 0.1 0.00029 20.7 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EON30746.1 - 0.0053 16.9 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_S18 PF01084.20 EON30747.1 - 2.7e-22 78.7 0.1 3.7e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Herpes_glycoH_C PF17488.2 EON30747.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 1 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain Ribosomal_L9_C PF03948.14 EON30748.1 - 1.6e-25 89.4 0.1 2.2e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 EON30748.1 - 9e-21 73.2 0.4 1.8e-20 72.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DnaB_C PF03796.15 EON30750.1 - 2e-93 312.4 2.8 5.3e-82 275.0 0.9 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain DnaB PF00772.21 EON30750.1 - 2.9e-33 114.0 0.0 7.9e-33 112.6 0.0 1.8 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 EON30750.1 - 1e-09 38.2 1.2 6.6e-08 32.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EON30750.1 - 0.34 10.2 1.2 2.4 7.4 0.0 2.3 2 1 0 2 2 2 0 KaiC Baculo_PEP_C PF04513.12 EON30751.1 - 0.0034 17.4 4.8 0.0034 17.4 4.8 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 EON30751.1 - 0.017 15.2 1.4 0.056 13.5 0.9 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Prominin PF05478.11 EON30751.1 - 0.032 12.2 0.1 0.045 11.7 0.1 1.2 1 0 0 1 1 1 0 Prominin COG2 PF06148.11 EON30751.1 - 0.033 14.3 0.1 0.32 11.1 0.2 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EON30751.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) BST2 PF16716.5 EON30751.1 - 0.053 14.1 1.0 4.6 7.9 0.1 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 EON30751.1 - 0.074 13.7 0.6 0.19 12.3 0.4 1.8 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AIP3 PF03915.13 EON30751.1 - 0.15 11.1 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DASH_Dad2 PF08654.10 EON30751.1 - 0.16 12.4 6.6 11 6.5 0.3 3.3 2 1 1 3 3 3 0 DASH complex subunit Dad2 DUF3584 PF12128.8 EON30751.1 - 0.17 9.4 1.3 0.23 8.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T3SSipB PF16535.5 EON30751.1 - 0.17 12.3 11.5 3.3 8.2 1.0 2.8 1 1 0 2 2 2 0 Type III cell invasion protein SipB Spc7 PF08317.11 EON30751.1 - 0.27 10.1 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein WXG100 PF06013.12 EON30751.1 - 0.37 11.0 9.4 8.3 6.7 0.0 4.2 3 2 2 5 5 5 0 Proteins of 100 residues with WXG ATG_C PF09333.11 EON30751.1 - 0.52 10.7 2.6 3.4 8.1 0.0 3.1 2 2 1 3 3 3 0 Autophagy-related protein C terminal domain GARP PF16731.5 EON30751.1 - 2.6 7.7 9.3 4.7 6.9 2.1 2.7 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma ADH_zinc_N PF00107.26 EON30753.1 - 6.9e-35 119.9 1.0 1.2e-34 119.0 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON30753.1 - 9.3e-32 109.2 0.9 1.7e-31 108.4 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EON30753.1 - 1.4e-14 55.2 0.3 2.2e-14 54.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON30753.1 - 2e-07 30.7 0.5 3.7e-07 29.9 0.5 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PK_C PF02887.16 EON30753.1 - 0.038 14.2 0.2 0.071 13.3 0.2 1.4 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain IGFBP PF00219.18 EON30753.1 - 0.17 12.6 2.9 0.19 12.4 1.3 1.8 2 0 0 2 2 2 0 Insulin-like growth factor binding protein 3HCDH_N PF02737.18 EON30753.1 - 0.17 11.7 1.4 0.29 11.0 1.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 EON30753.1 - 0.17 11.2 0.3 0.28 10.5 0.3 1.2 1 0 0 1 1 1 0 ThiF family FCD PF07729.12 EON30754.1 - 5.1e-21 75.4 10.4 9.3e-21 74.5 10.4 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON30754.1 - 5e-16 58.1 0.6 1e-15 57.1 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 EON30754.1 - 8.4e-06 25.4 0.0 5.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 EON30754.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 EON30754.1 - 0.074 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Flagellin_N PF00669.20 EON30754.1 - 0.078 13.1 0.2 1.8 8.7 0.2 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cob_adeno_trans PF01923.18 EON30754.1 - 0.085 13.0 0.2 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF768 PF05589.11 EON30754.1 - 0.2 11.7 0.7 0.39 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF768) ABC_tran_Xtn PF12848.7 EON30754.1 - 0.2 11.7 0.9 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 ABC transporter WES_acyltransf PF03007.16 EON30755.1 - 1.3e-50 172.6 0.4 1.7e-50 172.2 0.4 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON30755.1 - 4.4e-17 62.4 0.0 6.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) HAD PF12710.7 EON30756.1 - 4.5e-32 112.0 0.4 7e-32 111.4 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.21 EON30756.1 - 1.1e-25 89.9 0.0 2.1e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Hydrolase PF00702.26 EON30756.1 - 2.1e-07 31.5 0.1 8e-05 23.0 0.1 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON30756.1 - 0.0014 18.5 0.0 0.93 9.2 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E3_binding PF02817.17 EON30756.1 - 0.03 14.7 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 e3 binding domain Acyltransferase PF01553.21 EON30757.1 - 5.7e-16 58.4 0.0 1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF2236 PF09995.9 EON30758.1 - 1e-32 114.2 11.2 1.3e-32 113.9 11.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF5596 PF18082.1 EON30758.1 - 0.0021 17.9 0.1 0.0053 16.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5596) CSD PF00313.22 EON30759.1 - 1.6e-31 108.0 0.4 1.7e-31 107.9 0.4 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EON30759.1 - 0.00052 19.6 0.2 0.0007 19.2 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain Pkinase PF00069.25 EON30760.1 - 1.9e-39 135.6 0.0 2.9e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON30760.1 - 1.9e-27 96.2 0.0 3.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_MalT PF17874.1 EON30760.1 - 6e-16 58.7 3.5 6e-16 58.7 3.5 2.2 2 1 0 2 2 2 1 MalT-like TPR region AAA_16 PF13191.6 EON30760.1 - 4.1e-08 33.8 0.2 4.1e-08 33.8 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EON30760.1 - 7.1e-08 32.8 0.0 2.1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EON30760.1 - 0.0004 20.4 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ResIII PF04851.15 EON30760.1 - 0.0077 16.2 0.0 0.058 13.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_12 PF13424.6 EON30760.1 - 0.0082 16.4 23.0 0.26 11.6 3.7 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EON30760.1 - 0.0085 16.1 10.4 3.6 7.9 0.3 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat IstB_IS21 PF01695.17 EON30760.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 EON30760.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EON30760.1 - 0.065 12.8 2.2 0.085 12.4 0.3 2.2 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 EON30760.1 - 0.73 9.8 4.1 11 6.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EON30760.1 - 3.4 7.6 15.0 0.82 9.6 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EON30760.1 - 5 7.7 20.3 4.1 8.0 1.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EON30761.1 - 3e-47 161.2 0.0 2e-45 155.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PRNT PF15174.6 EON30761.1 - 0.18 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Prion-related protein testis-specific Peripla_BP_2 PF01497.18 EON30763.1 - 6.7e-24 84.7 0.1 1e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 EON30764.1 - 2.8e-35 121.8 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON30764.1 - 2.1e-11 44.2 0.1 7.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON30764.1 - 5.2e-07 29.3 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON30764.1 - 0.00012 22.5 0.8 0.00055 20.4 0.8 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EON30764.1 - 0.00047 20.7 0.0 0.00063 20.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON30764.1 - 0.0024 18.1 0.1 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EON30764.1 - 0.0032 17.2 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON30764.1 - 0.005 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EON30764.1 - 0.0052 17.1 1.4 0.041 14.2 1.4 2.1 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EON30764.1 - 0.008 15.8 0.3 0.016 14.8 0.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EON30764.1 - 0.01 15.8 0.2 0.027 14.4 0.1 1.8 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 EON30764.1 - 0.026 14.7 0.1 0.15 12.4 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EON30764.1 - 0.04 14.0 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 EON30764.1 - 0.043 12.6 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF3584 PF12128.8 EON30764.1 - 0.045 11.3 0.1 0.061 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_25 PF13481.6 EON30764.1 - 0.05 13.2 0.5 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EON30764.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 EON30764.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EON30764.1 - 0.084 13.1 0.6 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EON30764.1 - 0.12 11.5 0.0 0.97 8.6 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.29 EON30764.1 - 0.15 12.5 0.1 0.71 10.3 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EON30764.1 - 0.22 10.9 0.0 11 5.3 0.0 2.8 2 1 1 3 3 3 0 Bacterial TniB protein AAA_27 PF13514.6 EON30764.1 - 0.22 11.1 0.0 0.51 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EON30764.1 - 0.26 10.7 0.1 0.44 10.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein FecCD PF01032.18 EON30765.1 - 1.2e-90 303.7 44.5 1.5e-90 303.4 44.5 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EON30765.1 - 0.19 11.2 33.2 0.022 14.3 27.4 2.6 2 1 1 3 3 3 0 ABC 3 transport family Ldh_1_N PF00056.23 EON30766.1 - 2.4e-36 124.9 0.3 3.4e-36 124.4 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EON30766.1 - 7.8e-25 87.7 0.0 2.1e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 EON30766.1 - 0.0039 17.7 0.5 0.011 16.3 0.5 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_4 PF02056.16 EON30766.1 - 0.011 15.3 1.9 0.1 12.2 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase CoA_binding PF02629.19 EON30766.1 - 0.022 15.5 0.3 0.058 14.1 0.3 1.8 1 1 0 1 1 1 0 CoA binding domain 3HCDH_N PF02737.18 EON30766.1 - 0.025 14.5 1.8 0.055 13.4 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EON30766.1 - 0.043 12.8 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4C PF11975.8 EON30766.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain 2-Hacid_dh PF00389.30 EON30766.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Hydrolase_4 PF12146.8 EON30767.1 - 5.1e-12 45.6 0.2 5.5e-11 42.2 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON30767.1 - 3.1e-10 41.1 8.9 4.3e-10 40.6 8.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON30767.1 - 2.5e-08 33.9 0.0 1.8e-05 24.5 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EON30767.1 - 3e-07 29.4 0.1 0.00074 18.3 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EON30767.1 - 5.1e-06 26.3 0.1 6.7e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EON30767.1 - 1.4e-05 24.7 0.0 3.9e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EON30767.1 - 0.00077 19.0 0.0 0.0043 16.5 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 EON30767.1 - 0.063 12.1 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PAF-AH_p_II PF03403.13 EON30767.1 - 0.21 10.1 0.1 2.1 6.8 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Excalibur PF05901.11 EON30768.1 - 8.1e-12 45.6 0.2 1.1e-11 45.1 0.2 1.2 1 0 0 1 1 1 1 Excalibur calcium-binding domain HTH_18 PF12833.7 EON30769.1 - 2.8e-25 88.4 0.5 2.8e-25 88.4 0.5 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON30769.1 - 5.8e-19 67.7 0.0 7.8e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Glyoxalase PF00903.25 EON30770.1 - 3.4e-11 43.4 0.0 4.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1275 PF06912.11 EON30771.1 - 1.4e-23 83.8 32.1 1.6e-23 83.6 32.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Flavi_M PF01004.19 EON30771.1 - 0.039 13.7 1.7 0.039 13.7 1.7 2.0 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M MadM PF03818.13 EON30771.1 - 0.33 10.8 13.5 0.049 13.5 7.8 2.7 2 1 0 2 2 2 0 Malonate/sodium symporter MadM subunit DUF2786 PF10979.8 EON30772.1 - 9.2e-14 51.1 1.3 9.2e-14 51.1 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) LysR_substrate PF03466.20 EON30773.1 - 1.8e-29 102.6 0.7 1.8e-29 102.6 0.7 1.7 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EON30773.1 - 6.3e-19 67.7 2.0 1.3e-18 66.6 2.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 EON30773.1 - 0.0067 16.5 0.3 0.081 13.0 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EON30773.1 - 0.025 14.5 0.1 0.074 13.0 0.1 1.8 1 0 0 1 1 1 0 MarR family BPD_transp_1 PF00528.22 EON30774.1 - 1.3e-17 64.1 14.4 1.3e-17 64.1 14.4 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF4320 PF14208.6 EON30774.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) BPD_transp_1 PF00528.22 EON30775.1 - 2.6e-14 53.4 14.3 2.6e-14 53.4 14.3 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Metallophos PF00149.28 EON30776.1 - 1.3e-14 55.2 0.3 3.3e-14 53.9 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON30776.1 - 2.5e-07 31.0 0.1 4.2e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SBP_bac_8 PF13416.6 EON30777.1 - 1.1e-29 104.2 1.6 1.5e-29 103.7 1.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EON30777.1 - 4.4e-26 92.6 5.5 7e-26 91.9 5.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EON30777.1 - 0.0036 17.1 2.3 0.023 14.5 1.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein DUF1366 PF07104.11 EON30777.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) ABC_tran PF00005.27 EON30778.1 - 5.5e-32 111.1 0.0 8.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON30778.1 - 2.6e-07 30.8 0.2 0.0086 15.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 EON30778.1 - 3.9e-07 30.1 2.2 7.3e-07 29.3 0.8 2.2 2 0 0 2 2 2 1 TOBE domain OB_MalK PF17912.1 EON30778.1 - 6.6e-07 30.1 0.0 3.6e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 MalK OB fold domain AAA_16 PF13191.6 EON30778.1 - 8.6e-05 23.0 0.4 0.00027 21.4 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON30778.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EON30778.1 - 0.00048 20.3 0.0 0.0025 18.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain CysA_C_terminal PF17850.1 EON30778.1 - 0.0012 19.4 0.8 0.0049 17.4 0.1 2.5 2 0 0 2 2 2 1 CysA C-terminal regulatory domain AAA PF00004.29 EON30778.1 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EON30778.1 - 0.0022 17.7 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON30778.1 - 0.0026 17.2 0.0 0.14 11.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE PF03459.17 EON30778.1 - 0.0043 17.3 1.0 0.011 16.0 0.5 2.0 2 0 0 2 2 1 1 TOBE domain AAA_22 PF13401.6 EON30778.1 - 0.0065 16.7 0.1 0.023 15.0 0.0 2.0 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.21 EON30778.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EON30778.1 - 0.016 15.7 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EON30778.1 - 0.03 14.3 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EON30778.1 - 0.035 14.4 0.6 0.076 13.3 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EON30778.1 - 0.053 13.5 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EON30778.1 - 0.075 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EON30778.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EON30778.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Adeno_IVa2 PF02456.15 EON30778.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_18 PF13238.6 EON30778.1 - 0.12 13.0 0.0 0.56 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EON30778.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EON30778.1 - 0.14 11.7 0.7 0.29 10.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EON30778.1 - 0.14 11.8 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EON30778.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Peptidase_M90 PF06167.12 EON30780.1 - 0.0043 16.7 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 MFS_1 PF07690.16 EON30781.1 - 4.1e-28 98.3 53.8 3e-19 69.2 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EON30781.1 - 3e-07 29.4 10.0 3e-07 29.4 10.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EON30781.1 - 8.1e-07 28.2 18.4 9.3e-06 24.7 9.1 2.1 1 1 1 2 2 2 2 MFS_1 like family Peripla_BP_2 PF01497.18 EON30782.1 - 6.6e-18 65.1 0.0 7.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Transp_cyt_pur PF02133.15 EON30783.1 - 2.8 6.6 58.1 4.1 6.1 58.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Hydantoinase_B PF02538.14 EON30784.1 - 4.9e-137 457.5 0.0 6e-137 457.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EON30785.1 - 9.9e-85 284.3 4.6 2.1e-84 283.3 0.9 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EON30785.1 - 3.4e-48 163.7 1.4 3.2e-45 154.0 0.1 2.6 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region FtsA PF14450.6 EON30785.1 - 0.039 14.4 0.2 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Cell division protein FtsA AAA_lid_7 PF17867.1 EON30785.1 - 0.12 12.6 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain HTH_30 PF13556.6 EON30786.1 - 2.7e-17 62.3 2.4 3.3e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain PucR PF07905.11 EON30786.1 - 1.1e-06 28.9 0.0 4.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family HTH_8 PF02954.19 EON30786.1 - 0.0026 17.5 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Peripla_BP_5 PF13433.6 EON30787.1 - 1.4e-83 280.9 0.0 1.5e-83 280.8 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 EON30787.1 - 4.7e-62 210.6 1.0 5.4e-62 210.4 1.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EON30787.1 - 1.7e-10 40.5 0.0 4.2e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Glyco_tran_WecB PF03808.13 EON30787.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family HGD-D PF06050.13 EON30787.1 - 0.055 13.2 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Peptidase_S15 PF02129.18 EON30788.1 - 1.4e-46 159.3 0.0 2.3e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EON30788.1 - 4.7e-37 128.1 0.6 8.6e-37 127.2 0.6 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 EON30788.1 - 1.1e-06 28.3 0.3 1.9e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_76 PF03663.14 EON30789.1 - 8.4e-23 81.5 0.0 1.2e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Ribosomal_L10 PF00466.20 EON30790.1 - 1.7e-26 92.3 0.1 3.2e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3182 PF11379.8 EON30790.1 - 0.0028 16.7 0.1 0.0037 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) Ribosomal_L12 PF00542.19 EON30791.1 - 8.1e-28 96.6 10.4 8.1e-28 96.6 10.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EON30791.1 - 3.5e-18 65.0 8.2 3.5e-18 65.0 8.2 2.6 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain MelC1 PF06236.11 EON30791.1 - 0.05 13.7 0.2 0.05 13.7 0.2 1.6 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 AbiEi_1 PF09407.10 EON30792.1 - 0.026 14.8 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain Bac_transf PF02397.16 EON30793.1 - 7.6e-66 221.2 0.0 1.3e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 EON30793.1 - 5.7e-09 36.2 0.9 1e-08 35.4 0.3 1.8 1 1 0 1 1 1 1 CoA-binding domain Glyco_hydro_26 PF02156.15 EON30794.1 - 1.5e-08 34.5 1.4 1.7e-08 34.3 0.9 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 Glyco_hydro_cc PF11790.8 EON30794.1 - 5.2e-06 26.2 0.1 6.8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_72 PF03198.14 EON30794.1 - 0.023 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Glucanosyltransferase Acyl_transf_3 PF01757.22 EON30795.1 - 2.8e-27 95.7 32.0 5.2e-27 94.8 32.0 1.4 1 0 0 1 1 1 1 Acyltransferase family Glyco_trans_2_3 PF13632.6 EON30797.1 - 5.4e-22 78.7 1.7 5.4e-22 78.7 1.7 2.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EON30797.1 - 2.6e-20 72.6 0.0 5.6e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EON30797.1 - 9.4e-20 71.1 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON30797.1 - 1.3e-17 64.4 0.1 2e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 LIP PF03583.14 EON30798.1 - 8.6e-12 45.0 1.2 1.5e-07 31.0 2.3 2.1 2 0 0 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.8 EON30798.1 - 2.1e-08 33.8 0.2 3.6e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON30798.1 - 0.029 13.8 0.2 0.76 9.2 0.4 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_GDSL_2 PF13472.6 EON30799.1 - 4e-07 30.6 0.9 6.6e-07 29.9 0.9 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF5480 PF17576.2 EON30800.1 - 0.15 12.0 4.3 0.13 12.3 2.8 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5480) DUF1459 PF07312.11 EON30801.1 - 0.46 10.7 4.3 0.15 12.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) PMT_2 PF13231.6 EON30802.1 - 1.4e-06 28.6 6.2 1.4e-06 28.6 6.2 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_tranf_2_3 PF13641.6 EON30804.1 - 6.2e-30 104.8 0.0 8.5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON30804.1 - 7.7e-27 94.5 1.1 7.7e-27 94.5 1.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EON30804.1 - 1.9e-11 43.8 0.0 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EON30804.1 - 0.0018 18.1 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Abhydrolase_1 PF00561.20 EON30806.1 - 1.5e-19 70.6 0.1 7.7e-16 58.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON30806.1 - 4.6e-12 47.0 9.2 9.7e-12 45.9 9.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON30806.1 - 2.8e-11 43.1 0.0 2.7e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EON30806.1 - 0.00032 20.3 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.7 EON30806.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 EON30806.1 - 0.11 12.2 0.0 0.69 9.5 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ndr PF03096.14 EON30806.1 - 0.12 11.1 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Ndr family DUF2048 PF09752.9 EON30806.1 - 0.12 11.4 0.0 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 EON30807.1 - 4.9e-18 65.7 0.1 2.5e-12 47.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON30807.1 - 1.2e-09 39.1 13.8 1.8e-09 38.5 13.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON30807.1 - 8.4e-08 31.8 0.1 1.6e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EON30807.1 - 0.012 14.7 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 EON30807.1 - 0.013 15.4 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EON30807.1 - 0.12 11.8 1.7 0.22 11.0 1.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase CopD PF05425.13 EON30808.1 - 2.3e-19 69.7 10.6 2.3e-19 69.7 10.6 4.0 2 1 2 4 4 4 1 Copper resistance protein D UPF0182 PF03699.13 EON30808.1 - 5 5.1 5.4 1.5 6.8 2.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) CopC PF04234.12 EON30809.1 - 1.6e-24 86.7 0.2 2.1e-24 86.3 0.2 1.2 1 0 0 1 1 1 1 CopC domain Big_5 PF13205.6 EON30809.1 - 0.0045 17.7 0.2 0.0062 17.2 0.2 1.3 1 1 0 1 1 1 1 Bacterial Ig-like domain PsbX PF06596.11 EON30809.1 - 0.035 14.1 1.4 0.035 14.1 1.4 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF4131 PF13567.6 EON30809.1 - 0.1 12.2 2.8 2.4 7.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4381 PF14316.6 EON30809.1 - 3.4 7.9 6.5 0.78 10.0 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1775 PF07987.11 EON30810.1 - 2.6e-31 108.9 1.6 8.8e-31 107.2 1.6 1.8 1 1 0 1 1 1 1 Domain of unkown function (DUF1775) DUF3040 PF11239.8 EON30810.1 - 5.3 7.4 5.7 9.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) YtxH PF12732.7 EON30811.1 - 0.048 14.2 0.5 0.1 13.1 0.5 1.6 1 0 0 1 1 1 0 YtxH-like protein Acetyltransf_6 PF13480.7 EON30812.1 - 2.3e-06 27.8 0.3 5.3e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Phosphodiest PF01663.22 EON30813.1 - 2.6e-33 116.1 0.1 6.5e-33 114.8 0.1 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 EON30813.1 - 0.035 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 PglZ domain IMS PF00817.20 EON30814.1 - 7.9e-37 126.6 0.0 2.4e-36 125.0 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EON30814.1 - 2.1e-10 41.3 0.2 4e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EON30814.1 - 0.0027 17.9 0.0 0.0094 16.2 0.0 1.9 2 0 0 2 2 2 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 EON30814.1 - 0.038 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EON30814.1 - 0.059 14.0 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1805 PF08827.11 EON30814.1 - 0.15 12.4 0.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) RskA PF10099.9 EON30816.1 - 0.017 15.4 3.0 0.022 15.1 3.0 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4044 PF13253.6 EON30816.1 - 3.1 7.4 5.5 18 5.0 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4044) HSP70 PF00012.20 EON30817.1 - 4.8e-23 81.2 0.0 1.2e-22 79.9 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein Biotin_lipoyl_2 PF13533.6 EON30817.1 - 4e-06 26.5 0.1 0.0021 17.9 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like MreB_Mbl PF06723.13 EON30817.1 - 1.6e-05 23.9 0.0 5.1e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein HlyD_3 PF13437.6 EON30817.1 - 0.00073 20.2 0.2 0.96 10.2 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 EON30817.1 - 0.00095 19.0 0.0 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 EON30817.1 - 0.0076 15.5 0.0 1.2 8.3 0.0 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Keratin_B2_2 PF13885.6 EON30817.1 - 0.63 10.1 5.2 1.2 9.2 5.2 1.4 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Dynamin_N PF00350.23 EON30818.1 - 2.1e-12 47.4 1.5 2.3e-11 44.0 0.1 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EON30818.1 - 4.7e-08 33.1 0.0 1.9e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EON30818.1 - 3.6e-06 26.6 0.2 0.0042 16.6 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EON30818.1 - 0.0012 18.8 0.2 1.7 8.5 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 EON30818.1 - 0.0037 17.0 0.1 0.082 12.6 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EON30818.1 - 0.015 14.8 0.5 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 EON30818.1 - 0.092 12.0 0.7 1.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Septin AIG1 PF04548.16 EON30818.1 - 0.26 10.6 1.7 2.3 7.5 0.4 2.3 2 0 0 2 2 2 0 AIG1 family MMR_HSR1 PF01926.23 EON30819.1 - 3e-12 46.6 0.0 8.5e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EON30819.1 - 7.7e-12 45.6 0.0 4.7e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EON30819.1 - 0.00017 21.5 0.0 0.0047 16.8 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EON30819.1 - 0.00037 20.1 0.0 0.00082 19.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EON30819.1 - 0.0052 16.1 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 EON30819.1 - 0.0056 16.2 0.0 0.067 12.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 EON30819.1 - 0.0082 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EON30819.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EON30819.1 - 0.046 13.0 0.0 0.19 11.0 0.0 2.0 2 1 0 2 2 2 0 Septin SRPRB PF09439.10 EON30819.1 - 0.078 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit T2SSE PF00437.20 EON30819.1 - 0.082 11.9 0.0 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.6 EON30819.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma70_r2 PF04542.14 EON30821.1 - 1.4e-19 69.6 1.9 2.5e-19 68.8 1.9 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON30821.1 - 1e-13 50.7 0.2 1.9e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON30821.1 - 3e-08 33.1 0.2 6.5e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON30821.1 - 0.00055 19.9 0.6 0.071 13.0 0.6 2.1 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 EON30821.1 - 0.0031 17.0 0.1 0.0087 15.6 0.1 1.9 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 EON30821.1 - 0.004 16.9 0.4 0.031 14.1 0.0 2.3 2 1 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 EON30821.1 - 0.0076 16.4 2.4 0.011 15.8 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain UPF0122 PF04297.14 EON30821.1 - 0.063 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 EON30821.1 - 0.063 13.1 0.2 0.19 11.5 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 EON30821.1 - 0.076 12.9 2.6 0.12 12.2 0.1 2.6 3 1 1 4 4 4 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 EON30821.1 - 0.09 12.8 1.1 0.32 11.0 0.1 2.3 3 0 0 3 3 3 0 Winged helix-turn helix XTBD PF11952.8 EON30822.1 - 0.08 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD TMEMspv1-c74-12 PF11044.8 EON30823.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Phage_holin_2_3 PF16080.5 EON30823.1 - 0.029 14.1 1.0 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF4148 PF13663.6 EON30825.1 - 0.055 13.7 0.4 0.16 12.2 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) AAA_25 PF13481.6 EON30827.1 - 7.6e-08 32.2 0.1 3.8e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EON30827.1 - 3.9e-07 29.8 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EON30827.1 - 2.1e-05 24.0 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 EON30827.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_17 PF12728.7 EON30828.1 - 1.9e-11 44.0 0.1 2.2e-11 43.8 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 EON30828.1 - 2.4e-05 24.0 0.1 3.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 MerR family regulatory protein NUMOD1 PF07453.13 EON30828.1 - 0.00069 19.8 0.1 0.00094 19.4 0.1 1.2 1 0 0 1 1 1 1 NUMOD1 domain HTH_31 PF13560.6 EON30828.1 - 0.001 19.4 0.4 0.0016 18.7 0.4 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain MerR_1 PF13411.6 EON30828.1 - 0.0028 17.7 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_Tnp_ISL3 PF13542.6 EON30828.1 - 0.0033 16.8 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_DeoR PF08220.12 EON30828.1 - 0.0033 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain AbiEi_4 PF13338.6 EON30828.1 - 0.0036 17.4 0.1 0.0054 16.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin Sigma70_r4_2 PF08281.12 EON30828.1 - 0.0083 15.8 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 EON30828.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EON30828.1 - 0.014 15.1 0.1 0.018 14.8 0.1 1.3 1 1 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EON30828.1 - 0.018 15.2 0.4 0.04 14.0 0.4 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EON30828.1 - 0.018 15.1 0.1 0.024 14.7 0.1 1.4 1 1 0 1 1 1 0 Helix-turn-helix DUF746 PF05344.11 EON30828.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.3 2 0 0 2 2 1 0 Domain of Unknown Function (DUF746) HTH_29 PF13551.6 EON30828.1 - 0.03 14.4 0.2 0.038 14.0 0.2 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_psq PF05225.16 EON30828.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 helix-turn-helix, Psq domain HTH_24 PF13412.6 EON30828.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_1 PF00126.27 EON30828.1 - 0.089 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Mga PF08280.11 EON30828.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Phage_integrase PF00589.22 EON30829.1 - 1.5e-23 83.4 0.3 3.9e-23 82.1 0.1 1.8 2 1 0 2 2 2 1 Phage integrase family Arm-DNA-bind_4 PF14657.6 EON30829.1 - 0.019 14.7 1.5 0.088 12.6 1.5 2.1 1 1 0 1 1 1 0 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EON30829.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF4082 PF13313.6 EON30829.1 - 0.059 13.4 0.6 0.13 12.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) TetR_N PF00440.23 EON30830.1 - 7.9e-10 38.4 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EON30830.1 - 5.3e-08 33.2 3.0 5.3e-08 33.2 3.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_28 PF13518.6 EON30830.1 - 0.014 15.5 0.1 0.044 13.9 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 EON30830.1 - 0.024 14.7 0.2 0.045 13.8 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON30830.1 - 0.025 14.4 1.3 0.031 14.1 0.2 1.7 2 0 0 2 2 2 0 Homeodomain-like domain TetR_C_24 PF17932.1 EON30830.1 - 0.091 13.0 0.6 0.28 11.5 0.0 2.1 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2627 PF11118.8 EON30832.1 - 0.027 15.0 0.2 0.037 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) SmpB PF01668.18 EON30833.1 - 1.1e-59 200.5 0.4 1.3e-59 200.3 0.4 1.0 1 0 0 1 1 1 1 SmpB protein FtsX_ECD PF18075.1 EON30834.1 - 1.7e-15 57.4 0.0 3.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 EON30834.1 - 1.1e-07 32.2 12.8 7.1e-07 29.6 3.3 3.0 3 0 0 3 3 3 2 FtsX-like permease family DUF5423 PF17461.2 EON30834.1 - 0.56 9.0 4.0 0.54 9.1 1.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5423) DUF1430 PF07242.11 EON30834.1 - 1.7 8.9 5.2 1.5 9.1 0.3 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1430) ABC_tran PF00005.27 EON30835.1 - 1.7e-32 112.8 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON30835.1 - 3.3e-11 43.5 0.1 9.5e-06 25.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON30835.1 - 1.7e-05 25.1 0.0 9.1e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON30835.1 - 9.5e-05 22.8 0.0 0.0012 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EON30835.1 - 0.00027 21.1 0.4 0.003 17.7 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON30835.1 - 0.00035 20.2 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EON30835.1 - 0.00065 19.5 0.0 0.081 12.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EON30835.1 - 0.00069 19.1 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EON30835.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EON30835.1 - 0.0065 16.1 0.0 0.041 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EON30835.1 - 0.0068 16.8 0.0 0.21 12.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EON30835.1 - 0.031 14.8 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EON30835.1 - 0.036 14.0 0.0 0.046 13.6 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 EON30835.1 - 0.052 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EON30835.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EON30835.1 - 0.14 12.1 0.1 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EON30835.1 - 0.16 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON30835.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EON30835.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain MGC-24 PF05283.11 EON30836.1 - 0.87 10.0 4.8 1.3 9.5 4.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 EON30836.1 - 1.7 8.6 23.5 0.025 14.6 16.4 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein MS_channel PF00924.18 EON30837.1 - 9.6e-41 139.6 0.3 1.3e-40 139.1 0.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel PCRF PF03462.18 EON30838.1 - 9.5e-58 195.3 3.5 1.2e-57 194.9 1.5 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EON30838.1 - 6.1e-37 126.1 0.1 6.1e-37 126.1 0.1 2.1 2 1 1 3 3 3 1 RF-1 domain ABC_tran_CTD PF16326.5 EON30838.1 - 0.0015 18.7 1.7 0.0015 18.7 1.7 3.3 3 1 1 4 4 4 1 ABC transporter C-terminal domain MIR PF02815.19 EON30838.1 - 0.023 14.5 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 MIR domain Taxilin PF09728.9 EON30838.1 - 0.3 10.2 6.9 0.044 13.0 1.5 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Inositol_P PF00459.25 EON30840.1 - 8.7e-44 150.1 0.0 1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PND PF17949.1 EON30840.1 - 0.046 13.9 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 FANCM pseudonuclease domain Oxidored_FMN PF00724.20 EON30841.1 - 1.3e-49 169.3 0.0 1.7e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F420H2_quin_red PF04075.14 EON30841.1 - 2.5e-15 56.8 0.1 5.7e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase TetR_N PF00440.23 EON30842.1 - 2.8e-10 39.8 0.1 7.9e-10 38.4 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 EON30842.1 - 0.005 16.8 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain FrhB_FdhB_N PF04422.13 EON30842.1 - 0.078 13.1 1.1 4.8 7.4 0.1 2.7 3 0 0 3 3 3 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Lactamase_B_3 PF13483.6 EON30843.1 - 7.7e-22 77.9 0.1 9.6e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EON30843.1 - 5.9e-10 39.0 0.5 1.3e-09 37.8 0.5 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EON30843.1 - 1.1e-07 32.1 4.5 3.1e-07 30.6 4.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2752 PF10825.8 EON30844.1 - 3.2e-18 65.5 5.3 9.4e-18 64.0 4.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2752) Acyl-CoA_dh_N PF02771.16 EON30845.1 - 1.2e-24 87.2 0.2 2.5e-24 86.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON30845.1 - 2.5e-24 86.2 0.7 5.3e-24 85.1 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EON30845.1 - 3e-13 50.2 0.4 3e-13 50.2 0.4 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON30845.1 - 1.1e-08 35.2 0.0 3.1e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON30846.1 - 1.8e-38 132.1 1.8 2.9e-38 131.4 1.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON30846.1 - 2.6e-25 88.5 0.2 5.4e-25 87.4 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON30846.1 - 5.1e-10 39.7 3.6 1.3e-09 38.5 3.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AP_endonuc_2 PF01261.24 EON30846.1 - 0.034 13.6 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel CRCB PF02537.15 EON30847.1 - 6.3e-24 84.1 7.8 7.9e-24 83.8 7.8 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF543 PF04418.12 EON30847.1 - 0.1 12.6 0.5 0.1 12.6 0.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF543) CRCB PF02537.15 EON30848.1 - 7.8e-23 80.6 7.7 9.5e-23 80.3 7.7 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF2518 PF10726.9 EON30848.1 - 0.0006 19.5 1.9 0.00089 18.9 1.9 1.2 1 0 0 1 1 1 1 Protein of function (DUF2518) AMP-binding PF00501.28 EON30850.1 - 1.4e-86 290.8 0.5 1.8e-86 290.4 0.5 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON30850.1 - 4.3e-25 88.5 1.7 1.2e-24 87.0 0.3 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EON30850.1 - 9.1e-19 67.1 1.5 6.2e-18 64.5 0.8 2.4 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Putative_PNPOx PF01243.20 EON30851.1 - 3.7e-14 52.7 0.0 5.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Usp PF00582.26 EON30852.1 - 2.1e-10 41.3 0.7 3.1e-10 40.7 0.7 1.2 1 0 0 1 1 1 1 Universal stress protein family LAL_C2 PF18603.1 EON30852.1 - 0.12 12.6 4.3 1.8 8.8 0.1 2.5 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 HisKA_3 PF07730.13 EON30853.1 - 6.7e-16 58.6 7.0 1.7e-15 57.3 7.0 1.7 1 0 0 1 1 1 1 Histidine kinase Response_reg PF00072.24 EON30854.1 - 9.4e-27 93.4 0.0 1.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON30854.1 - 2.8e-17 62.0 0.0 4.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EON30854.1 - 2.2e-06 27.1 0.0 5.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EON30854.1 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 DUF742 PF05331.11 EON30854.1 - 0.057 13.2 0.0 0.33 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF742) HTH_10 PF04967.12 EON30854.1 - 0.1 12.4 0.1 0.73 9.7 0.1 2.2 1 1 0 1 1 1 0 HTH DNA binding domain DUF2089 PF09862.9 EON30854.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_23 PF13384.6 EON30854.1 - 0.28 11.0 1.8 0.35 10.7 0.1 2.0 3 0 0 3 3 3 0 Homeodomain-like domain GAF PF01590.26 EON30855.1 - 1.4e-09 38.6 0.0 2.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain Trans_reg_C PF00486.28 EON30855.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Pyr_redox_3 PF13738.6 EON30856.1 - 3.8e-17 62.5 0.1 1.3e-15 57.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON30856.1 - 4.9e-15 55.5 0.0 3.1e-11 43.1 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON30856.1 - 2.4e-14 52.7 0.0 1.1e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EON30856.1 - 3e-08 33.2 0.4 4e-06 26.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EON30856.1 - 8.7e-05 21.9 0.5 0.0017 17.7 0.1 2.9 4 0 0 4 4 4 1 FAD binding domain Pyr_redox PF00070.27 EON30856.1 - 0.00042 20.8 0.1 0.32 11.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON30856.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain IlvN PF07991.12 EON30856.1 - 0.01 15.4 0.1 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EON30856.1 - 0.012 14.7 0.2 3.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A SnoaL_2 PF12680.7 EON30856.1 - 0.042 14.5 1.9 0.13 12.9 0.4 2.5 3 0 0 3 3 3 0 SnoaL-like domain NAD_binding_9 PF13454.6 EON30856.1 - 0.051 13.6 1.0 3.3 7.7 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EON30856.1 - 0.059 12.4 0.1 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein OmdA PF13376.6 EON30857.1 - 4.2e-19 68.3 1.4 8.1e-19 67.4 1.4 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated adh_short_C2 PF13561.6 EON30859.1 - 9.5e-58 195.5 7.2 1.1e-57 195.3 7.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON30859.1 - 3.6e-46 157.1 2.4 4.4e-46 156.8 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON30859.1 - 1.6e-08 34.7 2.0 2.6e-08 34.0 2.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON30859.1 - 0.0023 17.4 1.0 0.0077 15.7 1.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EON30859.1 - 0.011 15.6 1.6 0.019 14.8 1.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EON30859.1 - 0.039 14.2 0.1 0.062 13.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4081 PF13312.6 EON30859.1 - 0.24 11.6 3.9 6.3 7.0 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4081) 2-Hacid_dh_C PF02826.19 EON30860.1 - 2.4e-53 180.1 0.0 3.4e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EON30860.1 - 0.00045 20.6 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EON30860.1 - 0.00067 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EON30860.1 - 0.0016 18.6 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 EON30860.1 - 0.0019 17.6 2.0 0.011 15.2 0.8 2.1 1 1 1 2 2 2 1 ThiF family F420_oxidored PF03807.17 EON30860.1 - 0.004 17.7 0.1 0.0088 16.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 EON30860.1 - 0.0042 16.4 0.8 0.0063 15.8 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EON30860.1 - 0.011 15.4 1.2 0.019 14.6 1.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EON30860.1 - 0.012 16.2 0.5 0.029 14.9 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 EON30860.1 - 0.019 15.4 0.1 0.037 14.5 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 EON30860.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.25 EON30860.1 - 0.023 14.1 0.1 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 EON30860.1 - 0.029 14.2 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EON30860.1 - 0.029 13.6 0.5 0.05 12.8 0.4 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TMP-TENI PF02581.17 EON30860.1 - 0.07 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase CoA_binding_2 PF13380.6 EON30860.1 - 0.072 13.6 0.4 0.2 12.2 0.1 1.9 2 0 0 2 2 2 0 CoA binding domain TrkA_N PF02254.18 EON30860.1 - 0.081 13.2 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 EON30860.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 EON30860.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RNase_H PF00075.24 EON30861.1 - 3.8e-47 160.1 0.0 4.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EON30861.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase-like Methyltransf_23 PF13489.6 EON30862.1 - 3.8e-15 56.1 0.0 5.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON30862.1 - 2.2e-13 50.2 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON30862.1 - 1.3e-12 48.2 0.0 3.4e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30862.1 - 1.5e-10 41.7 0.0 5.6e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON30862.1 - 2.7e-10 40.8 0.0 5.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON30862.1 - 1.3e-06 28.0 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EON30862.1 - 6.2e-05 23.0 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EON30862.1 - 0.057 12.9 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 EON30862.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 EON30862.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EON30862.1 - 0.25 10.7 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EON30862.1 - 0.26 11.0 0.0 0.56 9.9 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4185 PF13810.6 EON30863.1 - 5.7e-103 344.4 1.9 7.3e-103 344.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) BNR PF02012.20 EON30863.1 - 1 9.6 0.0 1 9.6 0.0 3.6 3 0 0 3 3 3 0 BNR/Asp-box repeat DUF1697 PF08002.11 EON30864.1 - 3e-34 118.4 0.0 3.7e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Rho_N PF07498.12 EON30864.1 - 0.032 14.2 0.1 0.41 10.6 0.0 2.4 2 1 0 2 2 2 0 Rho termination factor, N-terminal domain NeA_P2 PF12312.8 EON30864.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Acyl-CoA_dh_1 PF00441.24 EON30866.1 - 6.8e-43 146.4 1.4 1.1e-42 145.8 1.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON30866.1 - 3.3e-20 72.1 0.0 5.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON30866.1 - 3.1e-12 46.9 1.3 3.1e-12 46.9 1.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON30866.1 - 1.9e-11 44.6 0.3 7.3e-11 42.7 0.3 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain APH PF01636.23 EON30867.1 - 1.5e-33 116.7 8.7 2e-33 116.3 4.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EON30867.1 - 0.039 12.8 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EON30867.1 - 0.17 11.1 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase SnoaL_2 PF12680.7 EON30868.1 - 4.9e-10 40.0 0.8 8.9e-10 39.1 0.8 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON30868.1 - 8.3e-07 29.4 0.3 1.4e-06 28.6 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 EON30868.1 - 5.7e-05 23.2 0.3 0.00012 22.2 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 EON30868.1 - 0.00011 22.4 0.1 0.00064 20.0 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EON30868.1 - 0.00064 19.5 0.0 0.00089 19.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.20 EON30868.1 - 0.0071 16.9 0.0 0.0097 16.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF222 PF02720.17 EON30869.1 - 1.2e-21 77.5 11.8 1.6e-21 77.1 11.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON30869.1 - 2.9e-08 33.7 10.2 5.6e-08 32.8 10.2 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON30869.1 - 0.0094 15.8 4.1 0.019 14.8 4.1 1.4 1 0 0 1 1 1 1 HNH endonuclease CoA_binding_2 PF13380.6 EON30872.1 - 9.6e-36 122.8 1.0 1.1e-35 122.6 0.5 1.3 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 EON30872.1 - 0.0017 19.0 0.0 0.0029 18.2 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain 7TM_GPCR_Srw PF10324.9 EON30872.1 - 0.33 10.2 0.0 0.42 9.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw TetR_C_11 PF16859.5 EON30873.1 - 1.5e-20 73.6 10.0 1.5e-20 73.6 10.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON30873.1 - 9e-16 57.4 2.0 1.2e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON30873.1 - 0.0038 17.4 0.0 0.0073 16.5 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase APH PF01636.23 EON30874.1 - 2.7e-20 73.3 4.4 4.8e-20 72.5 4.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HIF-1 PF11413.8 EON30875.1 - 0.0042 16.5 0.3 0.0084 15.5 0.3 1.5 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 Complex1_30kDa PF00329.19 EON30875.1 - 0.043 14.4 0.0 0.081 13.5 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Methyltransf_25 PF13649.6 EON30876.1 - 4.9e-14 52.8 0.1 6.9e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON30876.1 - 2.7e-13 50.4 0.1 3.7e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EON30876.1 - 4.4e-11 42.4 0.0 5.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 EON30876.1 - 1.2e-08 35.0 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30876.1 - 3e-08 34.3 0.0 4.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EON30876.1 - 8.5e-05 22.3 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EON30876.1 - 0.0072 15.9 0.0 0.0099 15.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EON30876.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S41_N PF11918.8 EON30876.1 - 0.021 15.1 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP PCMT PF01135.19 EON30876.1 - 0.035 13.8 0.0 0.066 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Trans_reg_C PF00486.28 EON30877.1 - 1.2e-25 89.3 0.0 2.6e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EON30877.1 - 1.4e-24 86.4 0.0 2.2e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EON30878.1 - 2.9e-16 60.0 0.0 4.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON30878.1 - 2e-15 56.6 0.1 4.9e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EON30878.1 - 1.2e-13 51.2 1.0 1.2e-13 51.2 1.0 2.4 3 0 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 EON30878.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain VirB8 PF04335.13 EON30879.1 - 0.17 11.7 0.3 0.25 11.1 0.3 1.2 1 0 0 1 1 1 0 VirB8 protein SDA1 PF05285.12 EON30879.1 - 1.8 7.9 8.4 1.8 7.9 8.4 1.1 1 0 0 1 1 1 0 SDA1 DEC-1_N PF04625.13 EON30879.1 - 3 6.8 9.1 3.3 6.6 9.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1179 PF06678.11 EON30879.1 - 6.8 6.7 6.3 11 6.0 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) Hydrolase_4 PF12146.8 EON30880.1 - 0.00095 18.5 0.0 0.003 16.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON30880.1 - 0.0055 17.3 12.6 0.0086 16.7 12.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON30880.1 - 0.02 14.6 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DJ-1_PfpI PF01965.24 EON30881.1 - 2.6e-49 167.2 0.1 2.9e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 EON30881.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase PF00117.28 EON30881.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 EON30881.1 - 0.047 13.4 0.0 0.098 12.3 0.0 1.5 1 1 0 1 1 1 0 ThiJ/PfpI family-like MDMPI_N PF11716.8 EON30882.1 - 1.2e-12 48.7 0.7 1.2e-12 48.7 0.7 1.4 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON30882.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 DinB superfamily OPT PF03169.15 EON30883.1 - 7e-100 335.4 47.4 1e-99 334.9 47.4 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TetR_C_30 PF17939.1 EON30884.1 - 7.7e-07 29.3 0.1 1.3e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON30884.1 - 9.9e-07 28.5 0.1 2.8e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family GMC_oxred_C PF05199.13 EON30885.1 - 7.9e-15 55.6 0.1 1.7e-14 54.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EON30885.1 - 1.1e-07 31.4 0.2 1.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EON30885.1 - 8.4e-07 28.7 0.4 1.8e-05 24.3 0.4 2.6 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EON30885.1 - 8e-06 26.0 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON30885.1 - 6.6e-05 22.2 2.0 0.00017 20.8 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EON30885.1 - 0.00032 20.4 7.5 0.0033 17.1 6.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON30885.1 - 0.00035 19.9 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EON30885.1 - 0.0028 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EON30885.1 - 0.0063 15.9 1.6 0.015 14.7 1.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 EON30885.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.15 EON30885.1 - 0.049 12.2 0.1 0.073 11.6 0.1 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 EON30885.1 - 0.098 11.8 0.1 13 4.8 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EON30885.1 - 0.1 11.2 1.0 0.27 9.9 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.25 EON30887.1 - 2.5e-45 154.4 8.5 3e-45 154.1 8.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON30887.1 - 1.7e-33 116.1 8.7 2.7e-33 115.5 8.7 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON30887.1 - 1.8e-06 28.0 5.0 2.9e-06 27.3 3.9 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EON30887.1 - 2e-05 24.2 1.7 5.5e-05 22.8 1.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PglD_N PF17836.1 EON30887.1 - 0.0016 19.0 1.9 0.0016 19.0 1.9 2.1 3 0 0 3 3 3 1 PglD N-terminal domain Methyltransf_25 PF13649.6 EON30887.1 - 0.021 15.5 0.5 0.039 14.7 0.5 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 EON30887.1 - 0.061 13.6 0.9 0.3 11.3 1.2 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EON30887.1 - 0.42 10.5 3.1 0.69 9.8 3.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EON30887.1 - 1.6 8.0 4.4 0.94 8.8 2.4 1.7 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF5313 PF17240.2 EON30888.1 - 4.7e-45 153.0 1.9 5.9e-45 152.7 1.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5313) BPD_transp_1 PF00528.22 EON30888.1 - 0.027 14.2 2.0 0.034 13.9 2.0 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component MarR_2 PF12802.7 EON30889.1 - 8.3e-10 38.4 0.1 2e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EON30889.1 - 9.9e-10 38.2 0.1 3.7e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EON30889.1 - 1.1e-06 29.1 0.2 2.2e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EON30889.1 - 2.6e-05 23.9 0.1 7e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 EON30889.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EON30889.1 - 0.037 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EON30889.1 - 0.22 11.4 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CoA_transf_3 PF02515.17 EON30890.1 - 2.9e-112 375.4 2.7 3.3e-112 375.3 2.7 1.0 1 0 0 1 1 1 1 CoA-transferase family III Catalase PF00199.19 EON30891.1 - 1.2e-177 590.8 2.0 1.4e-177 590.5 2.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EON30891.1 - 2.5e-18 66.0 0.0 6.4e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive CinA PF02464.17 EON30892.1 - 3.2e-54 182.7 1.7 5.4e-54 182.0 1.7 1.3 1 0 0 1 1 1 1 Competence-damaged protein MoCF_biosynth PF00994.24 EON30892.1 - 3.7e-34 117.4 0.1 8e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain T7SS_ESX_EspC PF10824.8 EON30892.1 - 0.038 14.4 3.4 3.3 8.2 0.2 2.7 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Phage_CP76 PF06892.11 EON30893.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) Hemerythrin PF01814.23 EON30896.1 - 3.3e-15 56.9 4.3 3.3e-15 56.9 4.3 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain MeaB PF03308.16 EON30896.1 - 0.17 10.8 0.6 0.54 9.2 0.1 1.8 1 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zincin_1 PF06262.11 EON30897.1 - 4.3e-31 106.9 0.2 5.7e-31 106.5 0.2 1.1 1 0 0 1 1 1 1 Zincin-like metallopeptidase DUF3810 PF12725.7 EON30897.1 - 0.13 11.5 0.9 0.18 11.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Septum_form PF13845.6 EON30898.1 - 8.9e-74 247.8 0.1 1.1e-73 247.6 0.1 1.1 1 0 0 1 1 1 1 Septum formation PaaX PF07848.12 EON30899.1 - 5.6e-08 32.9 0.3 1.1e-07 32.0 0.3 1.4 1 0 0 1 1 1 1 PaaX-like protein PaaX_C PF08223.11 EON30899.1 - 1.5e-07 31.6 0.1 2.4e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain GntR PF00392.21 EON30899.1 - 0.025 14.2 0.8 0.14 11.8 0.1 2.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family AidB_N PF18158.1 EON30900.1 - 6.1e-50 169.2 0.0 1.4e-49 168.0 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON30900.1 - 5.3e-26 91.6 4.2 1.1e-25 90.6 4.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON30900.1 - 7.4e-18 64.5 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON30900.1 - 4.7e-08 33.4 1.0 4.7e-08 33.4 1.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 EON30901.1 - 1.3e-33 116.4 0.0 4.1e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON30901.1 - 9.6e-18 64.8 0.0 1.2e-16 61.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACP_syn_III_C PF08541.10 EON30901.1 - 0.034 14.3 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SDH_sah PF01972.16 EON30901.1 - 0.043 12.8 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Cation_efflux PF01545.21 EON30902.1 - 2.1e-08 34.1 2.0 2.7e-08 33.8 2.0 1.1 1 0 0 1 1 1 1 Cation efflux family TetR_C_20 PF17925.1 EON30902.1 - 0.01 16.1 0.6 0.17 12.2 0.0 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1422 PF07226.11 EON30902.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Phage_holin_2_4 PF16082.5 EON30902.1 - 0.31 10.8 2.7 0.26 11.1 0.4 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF202 PF02656.15 EON30902.1 - 5.7 7.5 8.2 83 3.7 5.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Ank_5 PF13857.6 EON30903.1 - 2e-11 43.9 1.1 1.1e-06 28.8 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EON30903.1 - 9.8e-10 38.9 0.0 1.4e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EON30903.1 - 8.3e-07 29.2 0.5 0.00088 19.6 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EON30903.1 - 1e-06 28.6 0.0 0.0075 16.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EON30903.1 - 3e-06 27.7 0.0 0.00077 20.0 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) tRNA-synt_2b PF00587.25 EON30904.1 - 6.6e-27 94.6 0.0 1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EON30904.1 - 4.6e-25 88.0 2.0 6.5e-25 87.5 2.0 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Peptidase_S46 PF10459.9 EON30904.1 - 0.039 12.6 0.1 0.051 12.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Jnk-SapK_ap_N PF09744.9 EON30904.1 - 0.091 13.0 0.9 0.16 12.2 0.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 EamA PF00892.20 EON30905.1 - 5.2 7.2 41.4 0.099 12.8 11.5 4.4 2 2 1 4 4 4 0 EamA-like transporter family TetR_N PF00440.23 EON30906.1 - 7.6e-19 67.2 1.9 1.6e-18 66.2 1.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 EON30906.1 - 0.031 14.1 0.8 0.031 14.1 0.8 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family UPF0122 PF04297.14 EON30906.1 - 0.075 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Glyoxalase PF00903.25 EON30907.1 - 1.2e-07 32.0 0.1 2.1e-07 31.2 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EON30907.1 - 7.8e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EON30907.1 - 0.11 13.3 0.1 0.15 12.9 0.1 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain Mg_trans_NIPA PF05653.14 EON30908.1 - 2.4e-05 23.6 5.6 2.4e-05 23.6 5.6 1.9 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 EON30908.1 - 0.0014 18.9 32.2 0.087 13.0 14.3 3.4 2 2 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 EON30908.1 - 1.2 9.2 7.0 0.066 13.2 1.1 2.0 2 1 0 2 2 2 0 Putative transmembrane family 234 FUSC-like PF12805.7 EON30908.1 - 6 5.8 6.5 17 4.4 6.5 1.9 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS LIP PF03583.14 EON30909.1 - 8.3e-42 143.5 0.0 1.1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 EON30909.1 - 0.0059 17.2 10.5 0.0059 17.2 10.5 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Acetyltransf_7 PF13508.7 EON30910.1 - 0.031 14.7 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON30910.1 - 0.061 13.6 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF326 PF03860.16 EON30912.1 - 7.1e-12 44.9 51.3 8.6e-05 22.4 12.5 4.3 4 0 0 4 4 4 4 Domain of Unknown Function (DUF326) Molybdopterin PF00384.22 EON30913.1 - 0.0014 17.6 0.1 0.0016 17.5 0.1 1.0 1 0 0 1 1 1 1 Molybdopterin oxidoreductase LIP PF03583.14 EON30916.1 - 2e-60 204.5 0.0 2.8e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase TetR_N PF00440.23 EON30917.1 - 3.5e-08 33.1 0.1 7.7e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_22 PF17928.1 EON30917.1 - 0.0031 17.8 1.2 0.0066 16.8 1.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 EON30917.1 - 4.5 8.1 10.9 0.7 10.7 4.1 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rieske PF00355.26 EON30918.1 - 1.6e-07 31.2 0.1 3.5e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Lactamase_B_3 PF13483.6 EON30918.1 - 4e-06 26.8 0.0 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EON30918.1 - 4.1e-06 26.4 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acyltransferase PF01553.21 EON30919.1 - 1.5e-29 102.3 0.0 2e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 EON30919.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Acyltransferase PF01553.21 EON30920.1 - 5.9e-25 87.4 0.0 8e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Hydrolase_3 PF08282.12 EON30921.1 - 3.9e-53 180.8 0.0 4.4e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EON30921.1 - 3.9e-10 39.7 0.0 7.4e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EON30921.1 - 7.5e-10 39.4 0.8 0.00022 21.6 0.2 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON30921.1 - 3.9e-06 27.4 2.8 0.11 12.9 0.1 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EON30921.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Amidase_2 PF01510.25 EON30922.1 - 5.2e-16 59.3 0.0 8.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase SOG2 PF10428.9 EON30922.1 - 1.9 7.6 6.7 2.6 7.1 6.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SpoIID PF08486.10 EON30923.1 - 4.3e-17 62.4 0.0 7.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein LGFP PF08310.11 EON30923.1 - 9.5e-06 26.1 1.2 4.6e-05 23.9 0.0 2.9 2 0 0 2 2 2 1 LGFP repeat ANTAR PF03861.14 EON30924.1 - 1.2e-21 76.3 1.5 3.7e-21 74.7 0.9 2.1 2 0 0 2 2 2 1 ANTAR domain GAF_2 PF13185.6 EON30924.1 - 2.2e-10 41.0 0.3 2.9e-10 40.6 0.3 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EON30924.1 - 0.00014 22.5 0.0 0.00018 22.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EON30924.1 - 0.016 15.6 0.1 0.029 14.7 0.1 1.4 1 0 0 1 1 1 0 GAF domain TetR_C_3 PF08362.11 EON30924.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region NodS PF05401.11 EON30925.1 - 9e-19 67.9 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 EON30925.1 - 7.1e-13 49.1 0.0 1.1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON30925.1 - 3.9e-11 43.0 0.0 5.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON30925.1 - 5.8e-11 42.9 0.0 8.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON30925.1 - 3.6e-10 40.5 0.0 4.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON30925.1 - 2.5e-09 36.9 0.0 4.3e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EON30925.1 - 3.1e-06 27.1 0.0 3.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EON30925.1 - 6.5e-06 25.6 0.0 6.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 EON30925.1 - 0.00076 19.0 0.0 0.0043 16.6 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain DUF3419 PF11899.8 EON30925.1 - 0.028 13.6 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) FmrO PF07091.11 EON30925.1 - 0.028 14.0 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PIG-L PF02585.17 EON30926.1 - 2.5e-22 79.9 0.1 3.8e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase TM_PBP2_N PF16296.5 EON30926.1 - 0.036 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters Acyl-CoA_dh_M PF02770.19 EON30927.1 - 5.8e-10 39.2 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glycos_transf_2 PF00535.26 EON30928.1 - 9e-14 51.6 0.1 1.3e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EON30928.1 - 0.00045 20.7 0.1 0.00093 19.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON30928.1 - 0.0068 16.3 5.5 0.031 14.2 5.5 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON30928.1 - 0.015 15.2 0.6 0.062 13.2 0.6 1.8 1 1 0 1 1 1 0 Glycosyl transferase family group 2 GLF PF03275.13 EON30929.1 - 8.8e-81 270.5 0.1 1.3e-80 270.0 0.1 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 EON30929.1 - 3.2e-18 65.7 0.1 9.1e-18 64.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON30929.1 - 1.3e-05 24.7 0.0 3.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EON30929.1 - 3.2e-05 23.5 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EON30929.1 - 0.00039 20.1 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON30929.1 - 0.001 19.6 0.0 0.0029 18.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON30929.1 - 0.0039 16.3 0.1 0.0058 15.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON30929.1 - 0.0052 16.1 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON30929.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EON30929.1 - 0.016 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EON30929.1 - 0.041 12.6 0.0 0.055 12.2 0.0 1.4 1 1 0 1 1 1 0 HI0933-like protein GDI PF00996.18 EON30929.1 - 0.11 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Glft2_N PF17994.1 EON30930.1 - 8.8e-65 216.9 0.1 1.8e-64 215.9 0.1 1.5 1 0 0 1 1 1 1 Galactofuranosyltransferase 2 N-terminal Glyco_tranf_2_3 PF13641.6 EON30930.1 - 4e-47 161.0 0.1 7.2e-47 160.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EON30930.1 - 0.00086 19.1 0.0 0.005 16.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 PAP2 PF01569.21 EON30931.1 - 3.2e-17 62.6 3.1 5e-17 61.9 3.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EON30931.1 - 6.4e-10 39.0 1.3 9.9e-10 38.4 1.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EON30931.1 - 0.0054 16.9 0.6 0.026 14.7 0.3 2.0 1 1 1 2 2 2 1 Divergent PAP2 family UbiA PF01040.18 EON30932.1 - 5.6e-20 71.7 23.0 5.6e-20 71.7 23.0 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Phage_holin_2_2 PF10746.9 EON30932.1 - 3.5 7.4 10.2 0.81 9.4 1.6 3.2 4 0 0 4 4 4 0 Phage holin T7 family, holin superfamily II Esterase PF00756.20 EON30934.1 - 4.1e-29 102.0 0.4 5.4e-29 101.6 0.4 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EON30934.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON30934.1 - 0.22 11.0 2.0 2.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_GDSL_2 PF13472.6 EON30935.1 - 1.4e-20 74.4 0.1 1.7e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON30935.1 - 0.00059 19.9 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ABC_tran PF00005.27 EON30936.1 - 1.6e-47 161.4 4.7 5.6e-23 82.0 0.0 3.2 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 EON30936.1 - 1.5e-15 57.8 9.7 5.5e-06 26.4 0.2 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 EON30936.1 - 6.7e-10 39.1 4.8 6.7e-10 39.1 4.8 2.5 3 0 0 3 3 2 1 ABC transporter C-terminal domain SMC_N PF02463.19 EON30936.1 - 5.3e-08 32.6 1.1 0.76 9.2 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON30936.1 - 1.7e-05 25.4 0.4 0.035 14.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain ABC_tran_Xtn PF12848.7 EON30936.1 - 3.5e-05 23.7 0.1 0.00095 19.1 0.0 2.5 3 0 0 3 3 2 1 ABC transporter RsgA_GTPase PF03193.16 EON30936.1 - 0.00033 20.6 0.5 0.75 9.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF3584 PF12128.8 EON30936.1 - 0.00073 17.2 8.0 0.058 10.9 0.1 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 EON30936.1 - 0.00078 19.5 2.7 0.42 10.7 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EON30936.1 - 0.001 19.5 0.2 0.001 19.5 0.2 3.3 3 2 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 EON30936.1 - 0.0011 18.7 0.2 0.0092 15.7 0.0 3.5 3 0 0 3 3 2 2 P-loop containing region of AAA domain MeaB PF03308.16 EON30936.1 - 0.0037 16.3 3.2 0.44 9.5 0.4 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Uds1 PF15456.6 EON30936.1 - 0.0083 16.3 1.5 0.25 11.5 0.1 2.6 1 1 1 2 2 2 1 Up-regulated During Septation DUF4407 PF14362.6 EON30936.1 - 0.036 13.4 0.2 0.1 11.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF87 PF01935.17 EON30936.1 - 0.057 13.5 2.0 3.9 7.5 0.6 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain GreA_GreB_N PF03449.15 EON30936.1 - 0.06 13.5 0.5 0.06 13.5 0.5 2.7 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal SRP54 PF00448.22 EON30936.1 - 0.078 12.6 0.2 13 5.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 EON30936.1 - 0.087 11.5 0.0 6.2 5.3 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 EON30936.1 - 0.1 12.3 0.1 10 5.7 0.1 3.2 4 0 0 4 4 4 0 AAA ATPase domain ATP-synt_ab PF00006.25 EON30936.1 - 0.11 12.2 0.1 7.2 6.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 EON30936.1 - 0.12 12.4 1.0 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Dynamin family TMF_TATA_bd PF12325.8 EON30936.1 - 0.14 12.4 0.4 0.28 11.4 0.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Plasmid_RAQPRD PF09686.10 EON30936.1 - 0.15 12.2 2.4 2 8.7 2.2 2.8 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Tropomyosin PF00261.20 EON30936.1 - 0.16 11.3 3.3 0.25 10.7 3.3 1.3 1 0 0 1 1 1 0 Tropomyosin RNA_helicase PF00910.22 EON30936.1 - 0.17 12.3 0.0 29 5.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase HalX PF08663.10 EON30936.1 - 0.65 10.3 11.3 0.13 12.6 1.1 3.5 2 1 1 3 3 3 0 HalX domain NACHT PF05729.12 EON30936.1 - 1.3 8.9 6.2 16 5.4 0.0 3.1 2 1 1 3 3 3 0 NACHT domain AAA_30 PF13604.6 EON30936.1 - 3.8 7.2 9.4 0.67 9.6 0.7 3.4 3 1 0 3 3 3 0 AAA domain Period_C PF12114.8 EON30936.1 - 9.6 5.7 5.8 15 5.1 5.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region LIP PF03583.14 EON30937.1 - 2.9e-14 53.1 0.8 4.7e-14 52.4 0.8 1.5 1 1 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 EON30937.1 - 1.4e-06 27.8 0.1 5.1e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON30937.1 - 5.3e-06 27.2 17.5 5.3e-06 27.2 17.5 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EON30937.1 - 1.5e-05 24.6 0.1 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EON30937.1 - 0.0014 18.5 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 EON30937.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EON30937.1 - 0.052 13.4 0.9 0.34 10.8 1.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 EON30937.1 - 0.17 11.5 0.4 0.3 10.7 0.4 1.4 1 1 0 1 1 1 0 Putative esterase GHMP_kinases_C PF08544.13 EON30938.1 - 3.7e-10 40.0 0.2 9.6e-10 38.7 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EON30938.1 - 1.3e-07 31.7 2.1 1.3e-07 31.7 2.1 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain HAD_2 PF13419.6 EON30939.1 - 6.5e-20 72.0 0.0 7.4e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON30939.1 - 2.2e-12 47.7 0.5 1.4e-11 45.1 0.5 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON30939.1 - 6.9e-09 36.4 1.1 8.7e-09 36.0 1.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON30939.1 - 4.1e-07 30.0 1.6 5.4e-07 29.6 0.1 2.0 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EON30939.1 - 0.005 16.9 0.0 0.29 11.3 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Citrate_bind PF16114.5 EON30939.1 - 0.23 11.0 0.1 0.34 10.4 0.1 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Bac_luciferase PF00296.20 EON30940.1 - 1e-48 166.4 6.1 1.4e-48 166.0 6.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase RrnaAD PF00398.20 EON30941.1 - 6.6e-37 127.0 0.0 8.2e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EON30941.1 - 0.0076 16.9 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FeoA PF04023.14 EON30941.1 - 0.037 14.3 0.1 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 FeoA domain DUF43 PF01861.16 EON30941.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Met_10 PF02475.16 EON30941.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Transglycosylas PF06737.14 EON30942.1 - 2.5e-33 114.5 7.1 3.9e-33 113.9 7.1 1.3 1 0 0 1 1 1 1 Transglycosylase-like domain DUF348 PF03990.14 EON30942.1 - 6.8e-24 83.3 14.4 1.6e-09 37.4 0.4 3.9 4 0 0 4 4 4 3 G5-linked-Ubiquitin-like domain G5 PF07501.12 EON30942.1 - 1.8e-17 63.6 10.6 1.8e-17 63.6 10.6 2.0 2 0 0 2 2 2 1 G5 domain CBM_11 PF03425.13 EON30942.1 - 0.065 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Ub-Mut7C PF14451.6 EON30942.1 - 0.12 12.3 0.1 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Mut7-C ubiquitin TatD_DNase PF01026.21 EON30943.1 - 1.2e-67 228.0 0.0 1.3e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EON30943.1 - 0.00028 20.8 9.6 0.0076 16.1 9.6 2.2 1 1 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 EON30943.1 - 0.0016 17.9 1.8 0.11 11.9 1.9 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Amidohydro_1 PF01979.20 EON30943.1 - 0.019 14.3 1.3 0.3 10.4 1.3 2.4 1 1 0 1 1 1 0 Amidohydrolase family PhzC-PhzF PF02567.16 EON30944.1 - 3.7e-52 177.5 0.0 4.3e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EON30944.1 - 0.032 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Proline racemase DUF3806 PF12713.7 EON30944.1 - 0.15 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) HAD_2 PF13419.6 EON30945.1 - 1.1e-14 54.9 0.0 3e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON30945.1 - 1.4e-13 51.6 1.4 2.1e-13 51.1 1.4 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EON30945.1 - 0.0018 18.4 0.0 0.03 14.4 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EON30945.1 - 0.0054 17.2 1.9 0.018 15.4 1.9 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON30945.1 - 0.035 14.1 1.4 1.1 9.4 0.3 2.5 2 0 0 2 2 2 0 HAD-hyrolase-like NT5C PF06941.12 EON30945.1 - 0.25 11.2 0.0 4.8 7.0 0.0 2.1 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Glyco_hydro_65m PF03632.15 EON30946.1 - 4e-122 407.8 0.0 5.1e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 EON30946.1 - 1.4e-64 217.9 0.0 2.2e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 EON30946.1 - 2e-13 50.0 0.0 9.9e-13 47.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain HEAT_2 PF13646.6 EON30947.1 - 5.1e-11 42.8 9.1 1.3e-06 28.7 0.4 3.3 2 2 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EON30947.1 - 0.41 11.0 6.7 27 5.4 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 EON30948.1 - 2e-18 66.6 25.5 4.8e-10 39.7 5.3 3.8 3 1 1 4 4 4 3 HEAT repeats MerR_1 PF13411.6 EON30948.1 - 4.9e-15 55.4 0.0 8.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EON30948.1 - 6.2e-15 54.7 0.5 1.4e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 MerR family regulatory protein HEAT PF02985.22 EON30948.1 - 2.4e-10 39.7 9.2 0.054 13.8 0.1 5.5 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 EON30948.1 - 6.2e-05 23.1 4.9 0.0025 17.9 0.3 3.8 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MerR-DNA-bind PF09278.11 EON30948.1 - 0.0027 18.2 1.8 0.0027 18.2 1.8 2.7 3 0 0 3 3 2 1 MerR, DNA binding Arm PF00514.23 EON30948.1 - 0.003 17.5 0.7 7.5 6.7 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EON30948.1 - 0.017 13.7 0.0 0.1 11.1 0.0 2.2 3 0 0 3 3 3 0 Adaptin N terminal region EH_Signature PF15611.6 EON30948.1 - 0.26 10.6 0.8 0.45 9.9 0.6 1.4 1 1 0 1 1 1 0 EH_Signature domain HEAT_PBS PF03130.16 EON30948.1 - 0.27 12.0 23.2 1.7 9.5 1.3 5.7 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EON30948.1 - 1.7 9.3 17.6 0.78 10.3 2.5 4.6 3 1 0 4 4 4 0 HEAT-like repeat DUF222 PF02720.17 EON30949.1 - 4.4e-27 95.4 10.0 5.5e-27 95.0 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON30949.1 - 6.2e-11 42.3 7.7 1.1e-10 41.5 7.7 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON30949.1 - 0.0011 18.8 2.8 0.0021 17.9 2.8 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 EON30949.1 - 0.38 10.9 5.3 2.2 8.5 5.3 2.1 1 1 0 1 1 1 0 HNH endonuclease tRNA-synt_1g PF09334.11 EON30950.1 - 1.2e-107 360.0 0.0 5.6e-106 354.6 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EON30950.1 - 1.3e-26 93.0 0.2 8.1e-13 47.5 0.0 3.8 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EON30950.1 - 4.2e-12 46.0 0.0 1.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EON30950.1 - 3.9e-05 22.8 0.0 0.087 11.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 EON30950.1 - 5.4e-05 23.2 0.0 0.00017 21.6 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA SEA PF01390.20 EON30950.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 SEA domain Chorismate_bind PF00425.18 EON30951.1 - 3.6e-70 236.5 0.0 4.9e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GAF PF01590.26 EON30952.1 - 0.0065 17.1 0.1 0.014 16.1 0.1 1.6 1 0 0 1 1 1 1 GAF domain Trans_reg_C PF00486.28 EON30952.1 - 0.017 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal TP_methylase PF00590.20 EON30953.1 - 1.4e-24 87.3 4.7 2e-24 86.7 4.7 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PMT_4TMC PF16192.5 EON30954.1 - 3e-18 66.1 18.7 3.5e-17 62.7 9.0 3.3 2 1 0 2 2 2 2 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 EON30954.1 - 8.3e-11 42.4 0.8 8.3e-11 42.4 0.8 3.8 3 1 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 EON30954.1 - 2.3e-10 40.5 10.5 2.3e-10 40.5 10.5 3.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF5313 PF17240.2 EON30955.1 - 9.3e-43 145.6 0.9 1.1e-42 145.3 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5313) Aminotran_1_2 PF00155.21 EON30956.1 - 3.6e-20 72.4 0.0 4.2e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EON30956.1 - 1.5e-16 59.7 0.3 4.9e-16 58.1 0.3 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 EON30956.1 - 0.04 13.6 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EON30956.1 - 0.065 13.2 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DegT_DnrJ_EryC1 PF01041.17 EON30956.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BCCT PF02028.17 EON30957.1 - 1.2e-174 581.4 45.0 1.4e-174 581.2 45.0 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter NDUF_B12 PF08122.12 EON30957.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.8 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family GntR PF00392.21 EON30958.1 - 7.7e-15 54.3 0.5 1.2e-14 53.7 0.5 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 EON30958.1 - 1.8e-06 27.7 0.8 5.7e-05 22.9 0.3 2.3 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EON30958.1 - 3e-05 23.9 0.1 5.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EON30958.1 - 4e-05 23.1 0.1 0.00013 21.4 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 EON30958.1 - 4.1e-05 23.2 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_CodY PF08222.11 EON30958.1 - 9e-05 22.0 0.3 0.0019 17.7 0.1 2.2 2 0 0 2 2 2 1 CodY helix-turn-helix domain HTH_20 PF12840.7 EON30958.1 - 0.00069 19.6 0.3 0.0016 18.4 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EON30958.1 - 0.0018 18.1 1.8 0.015 15.1 0.4 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Fe_dep_repress PF01325.19 EON30958.1 - 0.0018 18.5 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 EON30958.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 EON30958.1 - 0.015 15.1 0.1 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EON30958.1 - 0.024 15.0 0.1 0.039 14.3 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_Tnp_ISL3 PF13542.6 EON30958.1 - 0.027 13.9 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 EON30958.1 - 0.04 13.8 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 EON30958.1 - 0.046 13.5 0.1 0.49 10.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 EON30958.1 - 0.053 13.3 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 LexA DNA binding domain HTH_28 PF13518.6 EON30958.1 - 0.058 13.5 0.6 0.72 10.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EON30958.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Amidinotransf PF02274.17 EON30959.1 - 5.7e-102 341.3 0.0 6.5e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase MFS_1 PF07690.16 EON30960.1 - 5.3e-57 193.3 64.7 1.3e-29 103.3 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON30960.1 - 5.3e-16 58.5 39.7 6.6e-09 35.1 16.0 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter MFS_2 PF13347.6 EON30960.1 - 3.9e-15 55.3 34.3 3.1e-12 45.8 9.4 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 EON30960.1 - 1.4e-08 33.6 43.9 4.6e-07 28.6 9.4 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 EON30960.1 - 1.3e-07 30.8 24.2 3.8e-05 22.7 1.4 2.8 1 1 2 3 3 3 3 MFS_1 like family TRI12 PF06609.13 EON30960.1 - 0.00024 19.7 5.4 0.00024 19.7 5.4 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 EON30960.1 - 0.00062 18.7 2.0 0.00062 18.7 2.0 3.0 3 1 0 3 3 3 1 POT family LacY_symp PF01306.19 EON30960.1 - 0.0052 15.6 7.9 0.62 8.8 0.0 3.1 2 1 1 3 3 3 2 LacY proton/sugar symporter MFS_4 PF06779.14 EON30960.1 - 0.018 14.3 44.5 0.053 12.8 44.3 2.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Patatin PF01734.22 EON30961.1 - 1.4e-15 58.1 10.1 5.9e-14 52.7 10.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase MerR PF00376.23 EON30962.1 - 5.1e-14 51.7 0.2 1.2e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 EON30962.1 - 1.7e-13 50.4 0.0 2.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 EON30962.1 - 1.2e-12 48.2 0.0 1.9e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 MerR, DNA binding MarR_2 PF12802.7 EON30962.1 - 0.017 15.0 0.1 0.55 10.2 0.1 2.8 2 1 0 2 2 2 0 MarR family HTH_3 PF01381.22 EON30962.1 - 0.036 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Ribosomal_S18 PF01084.20 EON30962.1 - 0.058 13.6 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S18 HTH_17 PF12728.7 EON30962.1 - 0.081 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Usp PF00582.26 EON30963.1 - 7.7e-50 169.1 14.1 1.5e-28 100.1 1.2 2.0 2 0 0 2 2 2 2 Universal stress protein family Pox_P21 PF05313.12 EON30964.1 - 0.018 14.7 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF1772 PF08592.11 EON30964.1 - 0.2 11.9 4.3 0.23 11.8 2.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF3040 PF11239.8 EON30964.1 - 0.24 11.7 3.7 0.16 12.3 1.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.25 EON30965.1 - 0.018 14.4 0.0 0.054 12.9 0.0 1.7 1 1 1 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EON30965.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EON30966.1 - 1.2e-21 77.3 0.0 1.4e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON30966.1 - 2.3e-16 59.8 0.0 2.7e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON30966.1 - 0.0044 17.0 0.7 0.0083 16.1 0.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 EON30967.1 - 7.6e-51 173.1 41.0 1.2e-50 172.4 41.0 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FHA PF00498.26 EON30968.1 - 9.3e-08 32.3 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EON30968.1 - 0.036 14.4 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Sdh_cyt PF01127.22 EON30969.1 - 5.7 7.0 12.5 0.39 10.7 4.2 2.2 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Condensation PF00668.20 EON30971.1 - 1.9e-210 699.3 0.0 3.1e-72 243.7 0.0 3.2 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 EON30971.1 - 4.1e-170 565.9 1.0 6.5e-89 298.4 0.1 2.9 3 0 0 3 3 3 2 AMP-binding enzyme PP-binding PF00550.25 EON30971.1 - 3.2e-59 197.2 4.3 1.7e-15 57.1 0.1 5.6 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON30971.1 - 2.2e-40 137.5 15.5 3.9e-12 47.0 0.1 6.4 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EON30971.1 - 2.9e-24 86.5 0.0 1.8e-23 83.9 0.0 2.1 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EON30971.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AAA_19 PF13245.6 EON30972.1 - 9.2e-11 42.3 0.0 2.9e-09 37.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EON30972.1 - 7e-10 39.0 0.0 8.2e-05 22.4 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EON30972.1 - 5.2e-09 36.1 0.2 0.0014 18.2 0.1 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EON30972.1 - 2.1e-08 33.9 0.1 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein UvrD_C_2 PF13538.6 EON30972.1 - 5.3e-08 32.6 0.3 1.6e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EON30972.1 - 2.3e-06 27.5 0.4 0.086 12.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 EON30972.1 - 0.00038 19.8 0.7 0.004 16.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 EON30972.1 - 0.00068 19.1 0.0 0.034 13.5 0.0 2.5 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 EON30972.1 - 0.0016 18.3 0.0 0.0077 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON30972.1 - 0.0026 18.0 0.0 2.6 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EON30972.1 - 0.013 15.8 6.0 1 9.7 0.0 3.8 2 2 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 EON30972.1 - 0.016 14.9 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 EON30972.1 - 0.15 12.0 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MarR_2 PF12802.7 EON30973.1 - 0.055 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 MarR family DoxX PF07681.12 EON30974.1 - 7.6e-12 45.7 0.1 1.8e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 DoxX Apolipoprotein PF01442.18 EON30974.1 - 0.046 13.6 32.1 0.6 9.9 3.0 2.2 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EON30974.1 - 0.13 12.3 11.4 1.6 8.8 8.6 3.2 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 EON30974.1 - 0.26 11.8 29.1 14 6.3 7.1 4.3 1 1 1 2 2 2 0 YtxH-like protein Borrelia_P83 PF05262.11 EON30974.1 - 0.27 9.7 22.8 0.38 9.2 22.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein REF PF05755.12 EON30974.1 - 0.84 9.4 15.2 0.49 10.2 1.1 2.9 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) SNARE PF05739.19 EON30974.1 - 8.1 6.5 9.6 23 5.1 0.4 2.8 2 0 0 2 2 2 0 SNARE domain Lactamase_B PF00753.27 EON30975.1 - 5.3e-13 49.4 7.2 1.5e-12 47.9 7.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 EON30975.1 - 0.00068 19.2 0.0 0.00089 18.8 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON30975.1 - 0.049 13.2 1.3 0.077 12.5 1.3 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain UvrA_inter PF17760.1 EON30976.1 - 1.4e-38 131.3 0.3 4.1e-38 129.8 0.2 1.8 2 0 0 2 2 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 EON30976.1 - 9.1e-34 116.1 0.0 4.7e-32 110.6 0.0 2.9 4 0 0 4 4 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 EON30976.1 - 6.1e-19 68.9 0.0 3.5e-10 40.5 0.0 4.1 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 EON30976.1 - 5.5e-09 35.8 0.0 0.09 12.2 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON30976.1 - 1.8e-08 35.0 1.1 0.0095 16.3 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EON30976.1 - 5.2e-08 32.5 0.2 0.001 18.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EON30976.1 - 1.4e-06 28.4 1.0 0.2 11.4 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EON30976.1 - 5.7e-06 26.3 0.2 0.017 15.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EON30976.1 - 0.00011 21.8 0.1 0.77 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain DnaJ_CXXCXGXG PF00684.19 EON30976.1 - 0.00015 22.0 1.7 0.11 12.9 0.3 3.4 3 0 0 3 3 3 1 DnaJ central domain AAA_33 PF13671.6 EON30976.1 - 0.00022 21.4 0.2 2.1 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EON30976.1 - 0.00028 21.1 0.0 0.3 11.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 EON30976.1 - 0.00033 20.6 0.2 0.65 9.9 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_23 PF13476.6 EON30976.1 - 0.00036 21.1 0.0 0.97 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EON30976.1 - 0.00073 20.1 0.4 0.95 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EON30976.1 - 0.0037 17.2 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 EON30976.1 - 0.011 15.4 2.4 0.2 11.2 0.3 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zn-ribbon_8 PF09723.10 EON30976.1 - 0.015 15.4 6.8 38 4.5 0.0 4.5 4 0 0 4 4 4 0 Zinc ribbon domain Viral_helicase1 PF01443.18 EON30976.1 - 0.017 14.9 0.1 0.19 11.5 0.1 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EON30976.1 - 0.021 14.1 0.1 2.1 7.6 0.1 3.1 3 0 0 3 3 3 0 KaiC MMR_HSR1 PF01926.23 EON30976.1 - 0.027 14.5 0.2 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EON30976.1 - 0.037 14.1 0.0 4.5 7.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 EON30976.1 - 0.041 14.3 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ThiI PF02568.14 EON30976.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) AAA_24 PF13479.6 EON30976.1 - 0.088 12.5 0.3 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF2083 PF09856.9 EON30976.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Anti-TRAP PF15777.5 EON30976.1 - 0.14 12.2 5.7 28 4.7 0.0 3.9 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein T2SSE PF00437.20 EON30976.1 - 0.15 11.1 0.1 3.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 EON30976.1 - 0.16 11.2 0.1 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 EON30976.1 - 0.18 11.2 0.2 0.45 9.8 0.0 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 EON30976.1 - 0.18 11.5 0.0 20 4.8 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain SMG1 PF15785.5 EON30976.1 - 0.31 9.4 0.0 0.46 8.8 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 DNA_ligase_ZBD PF03119.16 EON30976.1 - 0.61 10.2 7.4 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DUF87 PF01935.17 EON30976.1 - 1.1 9.3 4.3 0.54 10.3 0.2 2.4 3 0 0 3 3 2 0 Helicase HerA, central domain Myc-LZ PF02344.15 EON30977.1 - 0.079 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Myc leucine zipper domain CLP_protease PF00574.23 EON30978.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Clp protease IF3_C PF00707.22 EON30979.1 - 6.1e-33 112.6 0.1 9e-33 112.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EON30979.1 - 7.7e-17 61.3 0.2 1.7e-16 60.3 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Ribosomal_L35p PF01632.19 EON30980.1 - 2.8e-27 95.0 7.1 3.1e-27 94.8 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 EON30981.1 - 1.6e-42 143.9 6.6 1.9e-42 143.7 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 SMC_ScpA PF02616.14 EON30981.1 - 0.069 13.0 0.3 0.074 13.0 0.3 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA SpoU_methylase PF00588.19 EON30982.1 - 1.8e-32 112.4 0.0 3.4e-32 111.6 0.0 1.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EON30982.1 - 6.7e-09 35.9 0.1 1.9e-08 34.4 0.0 1.8 2 1 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding PASTA PF03793.19 EON30982.1 - 0.072 13.0 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 PASTA domain eRF1_3 PF03465.15 EON30982.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 3 Tex_N PF09371.10 EON30983.1 - 5.2e-59 199.0 0.0 1e-58 198.1 0.0 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 EON30983.1 - 1.9e-48 164.1 0.2 3.5e-48 163.2 0.2 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 EON30983.1 - 2.4e-26 91.8 0.0 4.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 EON30983.1 - 3.5e-23 82.3 0.0 9.5e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 EON30983.1 - 1.1e-19 70.5 1.8 2e-19 69.7 1.8 1.4 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 EON30983.1 - 1.5e-06 28.5 0.0 3.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EON30983.1 - 1.6e-06 27.9 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 EON30983.1 - 0.099 12.9 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif CcmH PF03918.14 EON30984.1 - 2.6 7.3 12.1 3.9 6.7 0.3 3.9 4 0 0 4 4 4 0 Cytochrome C biogenesis protein RhodobacterPufX PF11511.8 EON30984.1 - 7 6.3 10.1 22 4.8 0.2 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX tRNA-synt_2d PF01409.20 EON30985.1 - 2.8e-96 321.8 0.0 3.2e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 EON30985.1 - 5.1e-17 61.6 0.1 8e-17 60.9 0.1 1.3 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain B3_4 PF03483.17 EON30986.1 - 3.8e-69 231.8 0.0 6e-69 231.2 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 EON30986.1 - 2.4e-57 193.8 0.0 3.7e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 EON30986.1 - 1.6e-24 86.1 0.0 2.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 EON30986.1 - 1.3e-17 63.6 0.0 2.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 EON30986.1 - 1.4e-14 54.2 0.0 2.8e-13 49.9 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain Semialdhyde_dhC PF02774.18 EON30987.1 - 2.4e-23 83.1 0.1 3.4e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EON30987.1 - 8.7e-21 74.6 0.0 2.2e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ArgJ PF01960.18 EON30988.1 - 1.7e-127 425.3 5.1 1.9e-127 425.1 5.1 1.0 1 0 0 1 1 1 1 ArgJ family AA_kinase PF00696.28 EON30989.1 - 1.5e-43 149.1 1.1 1.9e-43 148.8 1.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family Aminotran_3 PF00202.21 EON30990.1 - 2.7e-111 372.1 0.0 3.4e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EON30990.1 - 6.2e-06 25.7 0.0 7.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EON30990.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EON30990.1 - 0.052 12.5 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V OTCace PF00185.24 EON30991.1 - 1.9e-54 184.0 0.0 2.7e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EON30991.1 - 4e-43 147.0 0.0 6e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain MreB_Mbl PF06723.13 EON30991.1 - 0.091 11.6 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Arg_repressor_C PF02863.18 EON30992.1 - 6.9e-26 89.9 0.0 1e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain Arg_repressor PF01316.21 EON30992.1 - 9e-25 86.2 0.0 1.2e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain PDGF_N PF04692.13 EON30992.1 - 0.00061 20.5 0.4 0.00095 19.9 0.4 1.3 1 0 0 1 1 1 1 Platelet-derived growth factor, N terminal region Type2_restr_D3 PF16902.5 EON30992.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain PTE PF02126.18 EON30992.1 - 0.14 11.5 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Phosphotriesterase family Arginosuc_synth PF00764.19 EON30993.1 - 3.8e-184 612.4 0.0 4.4e-184 612.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EON30993.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EON30993.1 - 0.07 11.9 0.2 0.098 11.4 0.2 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Lyase_1 PF00206.20 EON30994.1 - 5.1e-64 216.6 0.0 7.8e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EON30994.1 - 7.6e-22 77.8 0.2 2e-21 76.5 0.2 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal AMP-binding PF00501.28 EON30995.1 - 3.1e-26 91.9 0.0 5.5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_6 PF12697.7 EON30995.1 - 2.1e-06 28.5 5.8 2.1e-06 28.5 5.8 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family AMP-binding_C PF13193.6 EON30995.1 - 8.4e-05 23.5 0.1 0.00024 22.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_1 PF00561.20 EON30995.1 - 0.00092 18.9 0.0 0.0029 17.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EON30995.1 - 0.002 18.3 0.1 0.0036 17.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EON30995.1 - 0.0023 17.2 0.1 0.028 13.7 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EON30995.1 - 0.0029 17.5 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PHB_depo_C PF06850.11 EON30995.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Trm112p PF03966.16 EON30996.1 - 0.0034 17.9 0.1 0.024 15.2 0.1 2.0 1 1 0 1 1 1 1 Trm112p-like protein tRNA-synt_1b PF00579.25 EON30997.1 - 6.5e-80 268.6 0.0 8.1e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EON30997.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 S4 domain MarR PF01047.22 EON30998.1 - 5.3e-14 51.9 0.0 9.1e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON30998.1 - 3.7e-12 45.9 0.7 1e-11 44.5 0.2 1.9 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 EON30998.1 - 0.0018 18.3 0.3 0.0076 16.3 0.1 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain CPT PF07931.12 EON30998.1 - 0.0047 16.8 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein HTH_Crp_2 PF13545.6 EON30998.1 - 0.026 14.5 0.2 0.05 13.6 0.2 1.6 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EON30998.1 - 0.037 13.8 0.2 0.15 11.8 0.2 2.3 1 1 0 1 1 1 0 IclR helix-turn-helix domain TrmB PF01978.19 EON30998.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EON30998.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 Transcriptional regulator Xan_ur_permease PF00860.20 EON30999.1 - 4.9e-27 94.6 39.2 7.1e-27 94.1 39.2 1.2 1 0 0 1 1 1 1 Permease family DUF2530 PF10745.9 EON31000.1 - 1.6e-28 98.8 2.7 1.8e-28 98.6 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) DUF4191 PF13829.6 EON31000.1 - 0.067 12.5 0.6 0.08 12.3 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Phosphonate-bd PF12974.7 EON31001.1 - 1.6e-39 135.9 0.2 1.9e-39 135.7 0.2 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EON31001.1 - 3.1e-06 27.3 0.0 6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_11 PF13531.6 EON31001.1 - 0.00073 19.4 0.2 0.0055 16.5 0.1 2.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_3 PF00497.20 EON31001.1 - 0.018 14.5 0.1 1.3 8.4 0.0 2.9 2 2 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 EON31001.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 NMT1-like family ABC_tran PF00005.27 EON31002.1 - 1.1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31002.1 - 4.3e-08 33.3 0.3 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON31002.1 - 0.00015 22.2 1.0 0.00052 20.4 0.9 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON31002.1 - 0.00055 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON31002.1 - 0.00092 19.3 0.1 0.0028 17.7 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EON31002.1 - 0.0022 18.3 0.2 0.022 15.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON31002.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EON31002.1 - 0.0031 17.0 0.0 0.033 13.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EON31002.1 - 0.0067 16.6 0.1 0.012 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF3652 PF12372.8 EON31002.1 - 0.011 15.7 0.2 0.024 14.5 0.2 1.6 1 0 0 1 1 1 0 Huntingtin protein region AAA_30 PF13604.6 EON31002.1 - 0.015 15.0 0.4 0.033 13.9 0.1 1.7 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EON31002.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 EON31002.1 - 0.032 14.3 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 EON31002.1 - 0.043 14.1 0.1 0.097 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON31002.1 - 0.05 13.2 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EON31002.1 - 0.054 13.4 0.6 0.11 12.4 0.2 1.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EON31002.1 - 0.11 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON31002.1 - 0.12 12.7 0.0 0.95 9.7 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EON31002.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON31002.1 - 0.19 11.5 0.4 0.32 10.7 0.3 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EON31002.1 - 0.23 10.6 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit BPD_transp_1 PF00528.22 EON31003.1 - 2.8e-20 72.8 13.7 2.8e-20 72.8 13.7 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 EON31003.1 - 4.8 7.7 23.7 0.53 10.8 6.7 3.0 3 0 0 3 3 3 0 FtsX-like permease family Y_phosphatase3 PF13350.6 EON31004.1 - 9.2e-44 150.1 0.0 1.1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family TetR_C_11 PF16859.5 EON31005.1 - 7.9e-09 35.8 7.2 7.9e-09 35.8 7.2 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON31005.1 - 2e-06 27.5 0.3 1e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_29 PF13551.6 EON31005.1 - 0.0063 16.5 2.1 1.4 9.0 0.1 2.8 3 0 0 3 3 3 2 Winged helix-turn helix HTH_7 PF02796.15 EON31005.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase KfrA_N PF11740.8 EON31005.1 - 0.065 13.9 0.8 0.11 13.2 0.8 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term TetR_C_14 PF17754.1 EON31005.1 - 0.1 12.6 5.9 0.038 13.9 3.1 1.8 2 0 0 2 2 2 0 MftR C-terminal domain AA_permease_2 PF13520.6 EON31006.1 - 9.3e-47 159.8 47.6 1.2e-46 159.4 47.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON31006.1 - 6.3e-30 104.2 42.8 8.5e-30 103.8 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 EON31006.1 - 0.00025 21.2 0.2 0.00025 21.2 0.2 3.5 3 0 0 3 3 3 1 Low psii accumulation1 / Rep27 DUF1358 PF07096.11 EON31006.1 - 0.095 12.7 4.2 0.42 10.6 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) APH PF01636.23 EON31007.1 - 3.8e-40 138.3 1.5 4.6e-40 138.0 1.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EON31007.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EON31007.1 - 0.25 10.7 0.0 0.42 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Acyl-CoA_dh_1 PF00441.24 EON31008.1 - 1e-30 106.9 0.5 2e-30 106.0 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON31008.1 - 9.6e-19 67.4 0.1 1.6e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON31008.1 - 5e-16 59.4 0.1 2e-15 57.4 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON31008.1 - 6.1e-06 26.5 1.1 1.3e-05 25.5 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON31008.1 - 0.0023 17.7 0.1 0.0041 16.8 0.1 1.4 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PQQ_2 PF13360.6 EON31009.1 - 1.5e-14 54.2 11.8 3.3e-10 39.9 1.4 2.7 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 EON31009.1 - 0.0092 15.9 0.1 43 4.3 0.0 4.3 3 1 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.6 EON31009.1 - 0.014 15.9 0.5 0.014 15.9 0.5 6.8 7 1 1 8 8 8 0 PQQ-like domain DUF222 PF02720.17 EON31010.1 - 1.3e-24 87.2 12.0 1.7e-24 86.9 12.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON31010.1 - 1.2e-08 35.0 11.4 1.2e-08 35.0 11.4 2.0 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 EON31010.1 - 0.039 13.8 5.7 0.087 12.7 5.7 1.5 1 0 0 1 1 1 0 HNH endonuclease PAP2 PF01569.21 EON31011.1 - 1.4e-16 60.5 10.3 1.4e-16 60.5 10.3 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EON31011.1 - 0.0022 18.5 12.2 0.0077 16.7 6.3 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DUF308 PF03729.13 EON31011.1 - 0.079 13.3 1.1 0.079 13.3 1.1 3.1 2 2 1 3 3 3 0 Short repeat of unknown function (DUF308) PTS_EIIC PF02378.18 EON31011.1 - 0.094 11.7 3.5 0.28 10.2 3.5 1.8 1 1 0 1 1 1 0 Phosphotransferase system, EIIC PAP2_3 PF14378.6 EON31011.1 - 0.13 11.9 19.4 0.43 10.2 18.4 2.2 1 1 0 1 1 1 0 PAP2 superfamily Hemerythrin PF01814.23 EON31012.1 - 3.3e-14 53.6 10.9 5.4e-14 52.9 10.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1525 PF07511.11 EON31012.1 - 0.015 15.4 0.1 0.034 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) FliT PF05400.13 EON31012.1 - 0.2 12.5 2.6 26 5.7 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Acyl-CoA_dh_1 PF00441.24 EON31013.1 - 1.5e-45 155.1 6.7 2.2e-45 154.5 6.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31013.1 - 1.9e-26 93.0 0.0 4e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31013.1 - 2.5e-23 82.1 0.0 4.9e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31013.1 - 1.9e-22 80.0 11.3 3.1e-22 79.3 11.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_N PF00440.23 EON31014.1 - 8.4e-07 28.7 0.7 1.9e-06 27.5 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON31014.1 - 0.00015 22.0 3.2 0.00023 21.4 0.1 2.7 3 1 1 4 4 4 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 EON31014.1 - 0.00021 21.3 2.5 0.0013 18.8 0.2 2.8 3 1 1 4 4 4 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 EON31014.1 - 0.01 15.9 2.7 0.013 15.5 0.6 2.1 2 2 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain HTH_23 PF13384.6 EON31014.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 EON31014.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF1472 PF07339.12 EON31015.1 - 0.074 13.6 0.7 0.26 11.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1472) DUF3027 PF11228.8 EON31016.1 - 1.1e-76 257.2 0.0 1.3e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) MFS_1 PF07690.16 EON31017.1 - 6.8e-15 54.8 21.5 6.8e-15 54.8 21.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EON31017.1 - 0.095 11.2 15.6 0.079 11.5 3.3 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein CW_7 PF08230.11 EON31017.1 - 0.16 11.8 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 CW_7 repeat CitMHS PF03600.16 EON31017.1 - 7.2 5.7 29.2 24 4.0 29.2 1.8 1 1 0 1 1 1 0 Citrate transporter DUF2771 PF10969.8 EON31018.1 - 3.3e-17 63.0 0.3 3.4e-17 62.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2771) CSD PF00313.22 EON31019.1 - 3.8e-15 55.5 0.0 5.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EON31019.1 - 0.0033 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain Flavin_Reduct PF01613.18 EON31021.1 - 4.3e-28 98.3 0.4 5.1e-28 98.1 0.4 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Mob_synth_C PF06463.13 EON31022.1 - 7.1e-33 113.3 0.0 1.1e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EON31022.1 - 7.9e-27 94.7 0.0 1.5e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EON31022.1 - 1.9e-06 28.2 0.0 3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EON31022.1 - 9.2e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain ThiS PF02597.20 EON31023.1 - 1.2e-05 25.8 0.0 1.6e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family DUF4129 PF13559.6 EON31023.1 - 0.019 15.2 1.2 0.023 14.9 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Transglycosylas PF06737.14 EON31024.1 - 1.8e-34 118.2 8.1 3.5e-34 117.3 8.1 1.5 1 0 0 1 1 1 1 Transglycosylase-like domain MoaE PF02391.17 EON31025.1 - 1.3e-31 109.1 3.3 1.6e-31 108.9 3.3 1.1 1 0 0 1 1 1 1 MoaE protein HHA PF05321.11 EON31025.1 - 0.072 13.4 0.2 0.21 11.9 0.2 1.9 1 1 0 1 1 1 0 Haemolysin expression modulating protein MoCF_biosynth PF00994.24 EON31026.1 - 1e-25 90.1 0.1 1.2e-25 89.8 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoaC PF01967.21 EON31027.1 - 2.2e-51 173.5 3.0 2.5e-51 173.3 3.0 1.0 1 0 0 1 1 1 1 MoaC family RCC1 PF00415.18 EON31029.1 - 2.8e-58 194.3 25.1 2.9e-08 34.2 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 EON31029.1 - 5.1e-42 144.1 0.0 7.2e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON31029.1 - 2.1e-18 66.5 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 EON31029.1 - 1.4e-15 56.6 60.9 0.0002 21.0 2.5 8.8 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat APH PF01636.23 EON31029.1 - 6.2e-07 29.6 8.3 0.0027 17.7 0.3 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON31029.1 - 0.00076 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF3357 PF11837.8 EON31029.1 - 0.048 14.1 1.6 0.083 13.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) AP_endonuc_2 PF01261.24 EON31029.1 - 0.081 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Kdo PF06293.14 EON31029.1 - 0.25 10.7 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCC1 PF00415.18 EON31030.1 - 2.8e-50 168.7 29.9 2.6e-08 34.4 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 EON31030.1 - 2.7e-39 135.1 0.0 4.5e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON31030.1 - 2.1e-20 73.1 0.0 2.9e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 EON31030.1 - 7.9e-20 70.1 49.3 0.00023 20.9 1.0 8.0 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Pkinase_fungal PF17667.1 EON31030.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EON31030.1 - 0.0017 18.3 0.2 0.2 11.5 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EON31030.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1459 PF07312.11 EON31030.1 - 0.16 12.2 19.4 9.8 6.5 0.1 6.3 3 1 2 6 6 6 0 Protein of unknown function (DUF1459) Pex14_N PF04695.13 EON31030.1 - 0.92 10.1 2.8 2.8 8.6 2.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IclR PF01614.18 EON31031.1 - 4.4e-21 75.0 0.2 7.2e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EON31031.1 - 1.2e-16 60.2 0.1 3.5e-16 58.7 0.1 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON31031.1 - 9.2e-05 22.3 0.1 0.00035 20.4 0.0 2.0 2 0 0 2 2 2 1 MarR family MarR PF01047.22 EON31031.1 - 0.0087 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EON31031.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HpcH_HpaI PF03328.14 EON31032.1 - 1e-08 34.6 0.9 3.6e-08 32.8 0.5 2.1 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Cupin_2 PF07883.11 EON31033.1 - 4.8e-22 77.4 0.4 2.2e-11 43.3 0.2 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EON31033.1 - 2e-11 43.4 0.2 6e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EON31033.1 - 7.7e-05 22.6 0.2 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 EON31033.1 - 0.00015 21.9 0.0 0.00049 20.2 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.22 EON31033.1 - 0.0042 16.7 0.2 3.7 7.2 0.0 2.4 2 1 0 2 2 2 2 Cupin Trans_reg_C PF00486.28 EON31034.1 - 5e-23 81.0 0.0 9.9e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EON31034.1 - 1e-17 64.3 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain TadZ_N PF16968.5 EON31034.1 - 0.11 12.2 0.6 0.23 11.2 0.6 1.6 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal HATPase_c PF02518.26 EON31035.1 - 4.1e-15 56.3 0.0 7.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON31035.1 - 2.3e-11 43.6 2.0 7.5e-11 41.9 2.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EON31035.1 - 4.3e-05 23.8 0.2 0.00014 22.2 0.2 2.0 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 EON31035.1 - 8.9e-05 22.5 0.8 0.0015 18.5 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain Sugar_tr PF00083.24 EON31036.1 - 2.6e-33 115.6 22.8 2.1e-23 82.9 5.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON31036.1 - 6.6e-30 104.2 53.8 1.3e-22 80.2 30.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AzlD PF05437.12 EON31036.1 - 0.00029 20.9 17.5 0.0035 17.5 0.1 4.4 5 0 0 5 5 5 2 Branched-chain amino acid transport protein (AzlD) CCSMST1 PF15013.6 EON31036.1 - 0.0003 20.9 0.5 0.077 13.2 0.0 3.2 3 0 0 3 3 3 1 CCSMST1 family Tti2 PF10521.9 EON31036.1 - 0.18 11.3 0.1 1.4 8.4 0.1 2.0 2 0 0 2 2 2 0 Tti2 family TetR_C_8 PF14278.6 EON31036.1 - 0.22 11.6 0.2 0.55 10.4 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region NMT1_3 PF16868.5 EON31037.1 - 1.3e-37 129.8 0.0 6.2e-37 127.6 0.0 1.8 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 EON31037.1 - 3e-09 37.2 0.0 4.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EON31037.1 - 4e-09 36.4 1.3 8.9e-09 35.3 1.3 1.6 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EON31037.1 - 0.0002 20.9 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 EON31037.1 - 0.0013 18.5 0.2 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 NMT1-like family TAT_signal PF10518.9 EON31037.1 - 0.088 12.7 0.2 0.088 12.7 0.2 5.0 7 0 0 7 7 7 0 TAT (twin-arginine translocation) pathway signal sequence LGFP PF08310.11 EON31038.1 - 1.8e-11 44.4 1.1 3.1e-06 27.6 0.2 2.5 2 0 0 2 2 2 2 LGFP repeat HNH PF01844.23 EON31039.1 - 1.2e-10 41.4 4.7 1.8e-10 40.8 4.7 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 EON31039.1 - 0.00052 20.1 2.0 0.0033 17.5 2.0 2.2 1 1 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON31039.1 - 0.0016 18.2 0.8 0.0026 17.6 0.8 1.3 1 0 0 1 1 1 1 HNH endonuclease Toxin_8 PF07365.12 EON31039.1 - 0.064 13.5 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Alpha conotoxin precursor Acyl-CoA_dh_1 PF00441.24 EON31040.1 - 1.6e-42 145.2 0.9 2.2e-42 144.8 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31040.1 - 6e-36 123.5 0.0 2e-34 118.6 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31040.1 - 1.6e-25 89.1 0.0 3.9e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31040.1 - 2.2e-18 66.8 0.8 3.5e-18 66.2 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EON31040.1 - 0.031 14.8 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal HpaB_N PF11794.8 EON31040.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PG_binding_4 PF12229.8 EON31040.1 - 0.16 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF5066 PF16728.5 EON31040.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Acyl-CoA_dh_1 PF00441.24 EON31041.1 - 3.5e-44 150.6 2.0 5.9e-44 149.9 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31041.1 - 2e-33 115.4 0.1 4.2e-33 114.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31041.1 - 3.1e-23 81.8 0.1 1.3e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31041.1 - 4.3e-19 69.1 0.7 6.9e-19 68.5 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Thiolase_N PF00108.23 EON31042.1 - 3.5e-67 226.5 0.4 5e-67 226.0 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON31042.1 - 9.9e-39 131.8 0.2 2.2e-38 130.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON31042.1 - 1.6e-05 24.7 2.3 1.6e-05 24.7 2.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EON31042.1 - 0.064 13.1 1.5 0.54 10.2 0.7 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 EON31043.1 - 1.5e-36 125.7 0.2 1.9e-36 125.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31043.1 - 2.1e-35 122.4 0.5 2.6e-35 122.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31043.1 - 1.1e-09 38.5 4.4 1.3e-08 35.0 4.4 2.1 1 1 0 1 1 1 1 KR domain Acyl-CoA_dh_1 PF00441.24 EON31044.1 - 1.5e-42 145.3 5.5 2.4e-42 144.7 5.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31044.1 - 5.1e-29 101.2 0.7 3.6e-28 98.5 0.0 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31044.1 - 2.9e-28 97.9 0.0 6.3e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31044.1 - 1.2e-17 64.5 4.7 2e-17 63.7 4.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON31044.1 - 0.00052 19.8 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 EON31044.1 - 0.19 12.3 0.0 0.39 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal adh_short_C2 PF13561.6 EON31045.1 - 1e-64 218.3 11.1 1.2e-64 218.0 11.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31045.1 - 3.1e-56 189.9 7.3 4e-56 189.6 7.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31045.1 - 1.2e-21 77.4 5.1 2.1e-21 76.7 5.1 1.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EON31045.1 - 0.00095 18.2 0.6 0.0013 17.8 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RNA_pol PF00940.19 EON31045.1 - 0.13 11.0 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase 3HCDH_N PF02737.18 EON31045.1 - 0.18 11.7 4.2 0.092 12.6 0.9 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CwsA PF10814.8 EON31045.1 - 1.1 9.4 7.7 0.19 11.9 1.9 2.5 2 1 1 3 3 3 0 Cell wall synthesis protein CwsA Thiolase_N PF00108.23 EON31046.1 - 3.3e-68 229.9 0.1 4.8e-68 229.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON31046.1 - 3.6e-42 142.9 0.1 8.4e-42 141.7 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON31046.1 - 0.00052 19.7 1.9 0.0011 18.6 0.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain LysR_substrate PF03466.20 EON31047.1 - 5.5e-25 88.0 4.0 7.1e-25 87.6 4.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EON31047.1 - 3.2e-21 75.0 1.5 2e-20 72.5 0.7 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family GntR PF00392.21 EON31047.1 - 0.026 14.2 0.3 0.067 12.8 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_5 PF01022.20 EON31047.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 EON31047.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_1 PF00126.27 EON31048.1 - 4.2e-24 84.3 0.2 1e-23 83.0 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EON31048.1 - 4.5e-24 85.0 6.6 6.5e-24 84.5 6.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 EON31048.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain DUF1922 PF09082.10 EON31048.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) SBP_bac_3 PF00497.20 EON31048.1 - 0.015 14.8 0.2 4.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 ECH_1 PF00378.20 EON31049.1 - 6.4e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31049.1 - 9.5e-26 91.1 0.3 8e-25 88.0 0.3 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 EON31049.1 - 0.025 14.8 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Peptidase_S49 PF01343.18 EON31049.1 - 0.03 14.3 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Lactamase_B PF00753.27 EON31050.1 - 1.5e-21 77.3 7.3 2.3e-21 76.7 7.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON31050.1 - 0.00012 21.6 1.0 0.00025 20.6 1.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ada3 PF10198.9 EON31050.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Abhydrolase_6 PF12697.7 EON31051.1 - 2.8e-09 37.9 5.1 4.1e-09 37.4 5.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31051.1 - 4.9e-07 29.2 0.9 7.8e-07 28.6 0.9 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON31051.1 - 1.9e-05 24.4 0.1 2.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EON31051.1 - 9.5e-05 22.2 2.0 0.00021 21.0 2.1 1.7 1 1 0 1 1 1 1 Putative esterase DUF2048 PF09752.9 EON31051.1 - 0.00075 18.7 0.2 0.0014 17.8 0.2 1.4 1 0 0 1 1 1 1 Abhydrolase domain containing 18 DUF2920 PF11144.8 EON31051.1 - 0.026 13.7 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Thioesterase PF00975.20 EON31051.1 - 0.029 14.5 0.2 0.048 13.8 0.2 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 EON31051.1 - 0.078 12.6 0.2 0.16 11.5 0.3 1.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.12 EON31051.1 - 0.22 11.5 0.0 0.79 9.6 0.0 1.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0227) ABC_tran PF00005.27 EON31052.1 - 1.5e-43 148.6 0.0 1.6e-24 87.0 0.0 3.6 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.6 EON31052.1 - 7.6e-25 88.3 14.8 4.6e-09 36.5 0.0 4.2 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON31052.1 - 1.1e-14 54.4 0.0 0.00052 19.5 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON31052.1 - 2.8e-10 40.3 1.1 0.0021 18.2 0.3 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EON31052.1 - 1.3e-09 38.1 2.5 0.0021 17.8 1.8 3.7 2 2 2 4 4 4 2 AAA domain AAA_29 PF13555.6 EON31052.1 - 3.4e-09 36.3 0.7 0.0024 17.6 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EON31052.1 - 6.5e-07 29.7 0.0 0.00031 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EON31052.1 - 1e-06 29.4 0.3 0.061 13.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EON31052.1 - 2.5e-06 27.5 0.0 0.019 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EON31052.1 - 3.9e-06 26.9 0.1 0.017 15.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EON31052.1 - 7.4e-05 23.2 10.0 0.00085 19.7 0.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EON31052.1 - 9.8e-05 22.7 4.3 0.3 11.3 0.0 3.8 3 1 1 4 4 4 2 AAA domain NACHT PF05729.12 EON31052.1 - 0.0001 22.2 0.1 0.066 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EON31052.1 - 0.00021 21.4 2.9 0.11 12.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EON31052.1 - 0.00023 21.0 0.0 0.47 10.1 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain NB-ARC PF00931.22 EON31052.1 - 0.0012 18.1 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 EON31052.1 - 0.0043 16.7 0.0 1 8.9 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EON31052.1 - 0.0056 16.4 0.1 1.3 8.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 EON31052.1 - 0.0069 16.0 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 EON31052.1 - 0.0095 15.9 0.0 4.4 7.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 EON31052.1 - 0.01 15.9 0.1 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EON31052.1 - 0.012 16.2 0.2 7.7 7.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 EON31052.1 - 0.012 14.9 2.1 3.2 7.0 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_7 PF12775.7 EON31052.1 - 0.014 14.9 0.0 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 EON31052.1 - 0.031 14.1 0.5 15 5.3 0.1 3.1 3 0 0 3 3 3 0 MukB N-terminal AAA PF00004.29 EON31052.1 - 0.039 14.4 0.2 2.5 8.5 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EON31052.1 - 0.043 14.0 0.0 5.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EON31052.1 - 0.048 13.7 0.0 3.1 7.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EON31052.1 - 0.062 12.9 6.6 0.6 9.7 0.1 3.7 2 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EON31052.1 - 0.07 12.9 0.1 7.5 6.2 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 EON31052.1 - 0.094 12.6 0.1 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 NTPase ABC_tran_Xtn PF12848.7 EON31052.1 - 0.12 12.4 0.5 0.23 11.5 0.5 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EON31052.1 - 0.14 12.5 0.0 6 7.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_27 PF13514.6 EON31052.1 - 0.23 11.0 3.4 14 5.2 0.0 3.2 3 1 1 4 4 4 0 AAA domain AAA_19 PF13245.6 EON31052.1 - 0.52 10.6 2.4 4.4 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain ECH_2 PF16113.5 EON31053.1 - 1.4e-110 369.9 0.0 1.6e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EON31053.1 - 9.9e-32 110.2 0.0 3.6e-31 108.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase GTP_EFTU PF00009.27 EON31055.1 - 1e-47 162.2 0.0 1.5e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 EON31055.1 - 2.4e-40 137.4 0.0 4.7e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EON31055.1 - 2.7e-07 30.6 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EON31055.1 - 0.00083 19.7 0.0 0.0024 18.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EON31055.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF433 PF04255.14 EON31055.1 - 0.08 12.8 0.1 2 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF433) RsgA_GTPase PF03193.16 EON31055.1 - 0.18 11.7 0.0 19 5.1 0.0 2.5 2 1 1 3 3 3 0 RsgA GTPase MTES_1575 PF18741.1 EON31056.1 - 3.4e-09 36.8 0.0 6.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 EON31056.1 - 3.6e-09 36.5 0.0 5.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) AbiEi_4 PF13338.6 EON31056.1 - 1.3e-08 34.9 2.0 1.3e-08 34.9 2.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin AbiEi_3_N PF17194.4 EON31056.1 - 0.0055 16.7 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain ACP_syn_III_C PF08541.10 EON31057.1 - 8.9e-30 102.7 1.9 1.6e-29 101.9 0.1 2.4 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EON31057.1 - 2.1e-26 91.6 0.5 2.1e-26 91.6 0.5 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EON31057.1 - 2e-07 30.7 2.0 2.7e-07 30.2 0.8 1.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 EON31057.1 - 4.1e-05 23.1 1.7 8.2e-05 22.1 1.7 1.6 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain SpoVAD PF07451.11 EON31057.1 - 0.033 12.9 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ABC_tran PF00005.27 EON31058.1 - 8.6e-28 97.6 0.0 1.7e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31058.1 - 6.6e-13 49.1 0.2 3e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EON31058.1 - 1.1e-06 29.2 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EON31058.1 - 0.00013 21.8 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EON31058.1 - 0.0044 17.6 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON31058.1 - 0.0045 16.7 1.1 0.0081 15.9 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON31058.1 - 0.0075 16.7 0.3 0.019 15.4 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EON31058.1 - 0.019 15.2 0.2 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON31058.1 - 0.042 13.6 0.9 0.16 11.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EON31058.1 - 0.047 13.9 0.1 0.85 9.9 0.0 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 EON31058.1 - 0.086 13.2 0.9 3.5 8.0 0.1 2.5 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 EON31058.1 - 0.12 12.0 0.4 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 EON31059.1 - 6.5e-27 94.3 12.8 1.1e-26 93.6 12.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON31059.1 - 9e-15 54.6 10.3 9e-15 54.6 10.3 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON31059.1 - 6.3e-07 29.0 11.0 9.1e-07 28.4 11.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF5336 PF17270.2 EON31059.1 - 0.041 13.5 0.1 0.041 13.5 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5336) Trep_Strep PF09605.10 EON31059.1 - 0.35 10.8 14.2 0.031 14.3 9.6 1.6 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) ACP_syn_III_C PF08541.10 EON31060.1 - 7.1e-30 103.0 1.4 8.2e-30 102.8 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EON31060.1 - 9e-26 89.5 0.5 2.5e-25 88.2 0.5 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EON31060.1 - 1e-07 31.6 0.0 2.2e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 EON31060.1 - 1.4e-05 24.6 0.2 2.2e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ketoacyl-synt PF00109.26 EON31060.1 - 0.095 12.3 5.7 0.28 10.7 1.3 2.5 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Pept_tRNA_hydro PF01195.19 EON31061.1 - 3.8e-42 144.2 0.0 4e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Rep_1B PF17873.1 EON31061.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Replicase polyprotein 1ab Ribosomal_L25p PF01386.19 EON31062.1 - 1.6e-25 89.4 0.1 3.3e-25 88.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 EON31062.1 - 2e-17 63.3 4.6 3.4e-17 62.6 4.6 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Pilosulin PF17499.2 EON31062.1 - 7.9 6.7 6.2 8.2 6.7 4.5 2.0 2 1 0 2 2 2 0 Ant venom peptides LEH PF07858.12 EON31063.1 - 2.6e-29 101.9 0.2 3.6e-29 101.4 0.2 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_2 PF12680.7 EON31063.1 - 3.2e-09 37.4 0.5 7.2e-09 36.2 0.2 1.7 2 0 0 2 2 2 1 SnoaL-like domain ArsC PF03960.15 EON31064.1 - 8.1e-12 45.0 0.0 9.5e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 EON31064.1 - 0.00079 19.6 0.0 0.0015 18.7 0.0 1.5 1 1 1 2 2 2 1 Glutaredoxin DUF4093 PF13331.6 EON31064.1 - 0.057 13.9 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Pribosyltran_N PF13793.6 EON31065.1 - 3.5e-42 143.0 0.0 7.5e-42 141.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EON31065.1 - 3.6e-20 72.8 0.1 8.2e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EON31065.1 - 1.1e-17 64.0 0.5 8.2e-17 61.2 0.3 2.5 1 1 2 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EON31065.1 - 5.7e-06 25.9 0.0 8.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Hexapep PF00132.24 EON31066.1 - 1.5e-20 72.0 9.2 3.2e-05 23.5 0.2 5.3 4 1 1 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EON31066.1 - 7.4e-17 62.2 5.8 1.9e-16 60.8 5.8 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EON31066.1 - 4.7e-16 59.1 0.0 7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EON31066.1 - 8.8e-10 38.2 2.6 0.022 14.5 0.1 6.0 6 0 0 6 6 6 3 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 EON31066.1 - 1.3e-07 31.6 0.7 2.5e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short_C2 PF13561.6 EON31067.1 - 1.5e-60 204.7 10.9 1.7e-60 204.5 10.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31067.1 - 6.3e-53 179.1 8.7 7.5e-53 178.9 8.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31067.1 - 1.7e-21 76.9 4.1 2.2e-21 76.6 4.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31067.1 - 1.7e-07 31.0 1.0 2.2e-07 30.6 1.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON31067.1 - 0.0046 16.4 0.1 0.006 16.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase CbiA PF01656.23 EON31067.1 - 0.066 13.3 0.0 0.086 12.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NmrA PF05368.13 EON31067.1 - 0.38 10.3 4.2 0.58 9.7 4.2 1.2 1 0 0 1 1 1 0 NmrA-like family Bac_luciferase PF00296.20 EON31068.1 - 3.3e-57 194.3 7.0 5.4e-57 193.6 7.0 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 EON31069.1 - 7e-28 98.0 14.8 1.7e-27 96.7 14.8 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 EON31070.1 - 1.9e-33 116.2 12.5 6.5e-25 88.2 4.2 2.1 2 0 0 2 2 2 2 Luciferase-like monooxygenase Putative_PNPOx PF01243.20 EON31072.1 - 8.9e-09 35.4 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase OpuAC PF04069.12 EON31073.1 - 5.8e-59 199.7 0.0 6.7e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1 PF09084.11 EON31073.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like BPD_transp_1 PF00528.22 EON31074.1 - 3.3e-17 62.8 20.3 3.3e-17 62.8 20.3 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Vma12 PF11712.8 EON31074.1 - 3.1 7.8 5.0 11 6.0 5.0 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ABC_tran PF00005.27 EON31075.1 - 8.1e-32 110.6 0.0 1.3e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EON31075.1 - 0.00016 22.1 0.1 0.0011 19.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EON31075.1 - 0.00028 20.8 0.0 0.73 9.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system CBS PF00571.28 EON31075.1 - 0.00031 21.1 2.1 0.0013 19.1 0.0 2.8 3 0 0 3 3 2 1 CBS domain AAA PF00004.29 EON31075.1 - 0.0028 18.1 0.0 0.031 14.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EON31075.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EON31075.1 - 0.0044 16.8 0.0 0.0064 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EON31075.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EON31075.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON31075.1 - 0.037 13.8 0.2 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EON31075.1 - 0.039 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 EON31075.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EON31075.1 - 0.064 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EON31075.1 - 0.081 13.2 0.6 0.35 11.1 0.6 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EON31075.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_ATPase PF09818.9 EON31075.1 - 0.15 10.8 0.0 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 EON31075.1 - 0.18 12.3 0.0 0.3 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EON31075.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region BPD_transp_1 PF00528.22 EON31076.1 - 5.9e-20 71.8 26.6 7.8e-20 71.4 26.6 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component VKOR PF07884.14 EON31077.1 - 7.2e-31 107.0 12.0 7.2e-31 107.0 12.0 1.7 2 0 0 2 2 2 1 Vitamin K epoxide reductase family DUF21 PF01595.20 EON31077.1 - 1.2 8.8 7.6 0.53 10.0 4.8 1.9 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain TetR_N PF00440.23 EON31078.1 - 4.1e-18 64.9 0.1 1.3e-17 63.3 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON31078.1 - 0.0011 19.2 0.1 0.0021 18.3 0.1 1.5 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_40 PF14493.6 EON31078.1 - 0.087 13.3 0.0 0.42 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Na_H_Exchanger PF00999.21 EON31079.1 - 1.8e-35 122.4 43.0 6e-34 117.4 43.0 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EON31079.1 - 3.6e-18 65.9 0.1 8.1e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EON31079.1 - 0.0089 15.4 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EON31079.1 - 0.03 14.2 0.1 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EON31079.1 - 0.17 12.1 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Acetyltransf_4 PF13420.7 EON31080.1 - 1.2e-19 70.9 0.0 1.5e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON31080.1 - 6.3e-12 45.8 0.0 8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON31080.1 - 7.3e-06 26.3 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON31080.1 - 9.6e-06 25.6 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON31080.1 - 0.00054 20.6 0.0 0.00066 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON31080.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EON31080.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein RalF_SCD PF18248.1 EON31080.1 - 0.16 11.9 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain CarD_CdnL_TRCF PF02559.16 EON31081.1 - 4.5e-30 104.2 0.0 1.1e-29 102.9 0.0 1.7 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 EON31081.1 - 3.3e-22 78.7 0.0 2.6e-21 75.8 0.0 2.3 2 0 0 2 2 2 1 TRCF domain UvrB_inter PF17757.1 EON31081.1 - 4.9e-21 74.7 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 EON31081.1 - 2.8e-17 63.1 0.9 2.4e-16 60.0 0.2 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON31081.1 - 3.3e-17 62.8 0.6 9.4e-14 51.7 0.1 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EON31081.1 - 1.1e-05 25.4 0.0 3.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EON31081.1 - 0.0011 17.7 0.3 0.023 13.4 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_30 PF13604.6 EON31081.1 - 0.037 13.8 0.4 0.65 9.7 0.1 2.8 2 1 1 3 3 3 0 AAA domain DUF3638 PF12340.8 EON31081.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) DUF1474 PF07342.11 EON31081.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) DAO PF01266.24 EON31082.1 - 6.9e-42 144.3 8.6 1.4e-41 143.3 8.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EON31082.1 - 6.4e-05 22.3 0.1 0.0048 16.2 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EON31082.1 - 0.00085 18.5 0.2 0.0016 17.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EON31082.1 - 0.01 15.4 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EON31082.1 - 0.027 14.3 0.2 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EON31082.1 - 0.03 14.5 0.2 0.067 13.4 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EON31082.1 - 0.052 13.2 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EON31082.1 - 0.053 12.8 0.2 0.6 9.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 EON31083.1 - 2.5e-25 88.5 1.1 2.5e-25 88.5 1.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EON31083.1 - 2.1e-10 40.5 0.1 3.7e-09 36.4 0.1 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 EON31083.1 - 3.8e-07 30.1 5.3 5.7e-07 29.6 0.4 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON31083.1 - 8.5e-05 23.6 0.1 0.0002 22.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EON31083.1 - 0.0016 18.3 0.7 0.0032 17.4 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EON31083.1 - 0.002 17.5 5.2 0.0029 16.9 5.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EON31083.1 - 0.0041 17.2 0.2 0.0076 16.3 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 EON31083.1 - 0.14 11.9 0.5 0.29 10.8 0.4 1.5 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_Gly3P_dh_N PF01210.23 EON31083.1 - 0.15 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EON31083.1 - 0.21 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BPD_transp_1 PF00528.22 EON31084.1 - 6e-36 123.9 30.6 6e-18 65.2 11.1 2.7 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EON31085.1 - 1.4e-30 106.6 0.0 1.9e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31085.1 - 4.4e-05 23.4 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON31085.1 - 0.0023 18.3 0.3 0.0042 17.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON31085.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EON31085.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON31085.1 - 0.03 14.6 0.1 0.063 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON31085.1 - 0.03 14.2 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EON31085.1 - 0.035 13.5 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON31085.1 - 0.045 14.0 0.1 0.83 9.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EON31085.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EON31085.1 - 0.086 13.3 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EON31085.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Phosphonate-bd PF12974.7 EON31086.1 - 1.6e-57 194.9 0.2 1.9e-57 194.7 0.2 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EON31086.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EON31086.1 - 0.0021 17.5 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Hydrolase PF00702.26 EON31087.1 - 3.9e-13 50.2 3.2 4e-12 46.9 3.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EON31087.1 - 4e-13 49.8 0.0 5.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON31087.1 - 3.6e-09 36.6 0.6 7.6e-09 35.5 0.6 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EON31087.1 - 2.1e-07 31.6 3.1 2.1e-07 31.5 1.7 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EON31087.1 - 0.021 14.9 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase UTRA PF07702.13 EON31088.1 - 3.4e-34 117.7 0.9 6e-34 116.9 0.9 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 EON31088.1 - 4.9e-11 42.1 0.6 1.1e-10 41.0 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EON31088.1 - 4.7e-05 23.3 0.3 0.00014 21.7 0.1 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EON31088.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_15 PF12324.8 EON31088.1 - 0.0068 16.3 0.5 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase HTH_DeoR PF08220.12 EON31088.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain FAA_hydrolase_N PF09298.11 EON31088.1 - 0.018 15.3 0.2 0.49 10.6 0.0 2.5 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal HTH_28 PF13518.6 EON31088.1 - 0.024 14.8 0.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EON31088.1 - 0.025 14.1 0.1 0.074 12.6 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_36 PF13730.6 EON31088.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 EON31088.1 - 0.05 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Transposase HTH_41 PF14502.6 EON31088.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EON31088.1 - 0.06 12.9 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EON31088.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Glyoxalase_6 PF18029.1 EON31089.1 - 2.2e-19 70.2 0.2 4.8e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Pterin_4a PF01329.19 EON31089.1 - 1.4e-18 66.9 0.0 2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ssDBP PF17878.1 EON31091.1 - 0.069 13.4 0.2 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Single-stranded DNA-binding protein MarR_2 PF12802.7 EON31093.1 - 0.0005 19.9 0.4 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EON31093.1 - 0.028 14.4 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 EON31093.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Lipase_2 PF01674.18 EON31094.1 - 4.2e-11 42.8 0.0 7.9e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EON31094.1 - 1.3e-08 34.8 0.2 1.9e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31094.1 - 3.1e-08 34.5 1.0 3.1e-08 34.5 1.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EON31094.1 - 8.1e-06 25.8 0.0 9.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EON31094.1 - 1.3e-05 24.6 0.1 1.8e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EON31094.1 - 0.00027 20.7 0.1 0.00041 20.1 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 EON31094.1 - 0.015 15.2 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 EON31094.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1749 PF08538.10 EON31094.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.12 EON31094.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Dr_adhesin PF12393.8 EON31094.1 - 3.4 8.1 7.0 11 6.5 7.0 1.9 1 0 0 1 1 1 0 Dr family adhesin PhyH PF05721.13 EON31096.1 - 8.3e-05 22.9 0.1 0.00013 22.3 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TetR_N PF00440.23 EON31097.1 - 8.4e-12 44.7 1.1 1.3e-11 44.1 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON31097.1 - 0.64 10.3 9.1 0.16 12.2 3.8 2.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_1 PF00561.20 EON31098.1 - 2.9e-31 109.0 0.1 3.5e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31098.1 - 1.1e-21 78.5 2.2 1.3e-21 78.3 2.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31098.1 - 5.3e-19 68.4 0.2 6.5e-18 64.9 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EON31098.1 - 0.017 14.9 0.0 6.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family Ndr PF03096.14 EON31098.1 - 0.035 12.8 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.10 EON31098.1 - 0.036 14.2 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein 3HBOH PF10605.9 EON31098.1 - 0.036 12.3 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) DLH PF01738.18 EON31098.1 - 0.08 12.5 0.1 0.48 9.9 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EON31098.1 - 0.11 12.0 0.4 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 EON31098.1 - 0.13 11.5 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) AHSA1 PF08327.11 EON31100.1 - 4.4e-19 68.9 0.1 5.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EON31100.1 - 0.00016 22.0 2.3 0.00021 21.6 2.2 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 EON31100.1 - 0.004 17.3 0.1 0.007 16.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) Polyketide_cyc PF03364.20 EON31100.1 - 0.0079 16.4 0.0 0.0079 16.4 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HTH_5 PF01022.20 EON31101.1 - 1.2e-09 37.9 0.4 2.3e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON31101.1 - 7.3e-09 35.6 0.3 7.3e-09 35.6 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 EON31101.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EON31101.1 - 0.0028 17.5 0.7 0.0047 16.8 0.7 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EON31101.1 - 0.019 15.3 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_28 PF13518.6 EON31101.1 - 0.027 14.6 0.6 0.049 13.8 0.6 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HxlR PF01638.17 EON31101.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DNA_pol3_delta2 PF13177.6 EON31102.1 - 8.5e-35 119.9 0.0 1.4e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EON31102.1 - 2.7e-06 27.8 0.0 6.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON31102.1 - 0.00026 21.3 0.0 0.00092 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DNApol3-delta_C PF09115.10 EON31102.1 - 0.0086 16.6 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal Mg_chelatase PF01078.21 EON31102.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EON31102.1 - 0.026 14.5 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON31102.1 - 0.069 13.5 0.1 0.069 13.5 0.1 3.2 2 2 0 2 2 2 0 AAA ATPase domain Guanylate_cyc PF00211.20 EON31103.1 - 4.5e-22 78.6 0.0 9.9e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 EON31103.1 - 1.7e-07 31.5 0.1 5.8e-07 29.8 0.1 2.0 1 0 0 1 1 1 1 HAMP domain LapA_dom PF06305.11 EON31103.1 - 0.4 10.5 4.8 4.1 7.3 0.1 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PHO4 PF01384.20 EON31103.1 - 0.53 9.3 14.3 0.29 10.2 9.5 1.9 1 1 1 2 2 2 0 Phosphate transporter family DUF5079 PF16882.5 EON31103.1 - 1.5 8.6 4.5 1.5 8.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) Topoisom_bac PF01131.20 EON31104.1 - 3.7e-119 398.4 0.0 3.7e-119 398.4 0.0 1.8 2 0 0 2 2 2 1 DNA topoisomerase Toprim_C_rpt PF13368.6 EON31104.1 - 8.1e-62 205.1 21.3 6.9e-20 70.8 0.0 6.3 6 0 0 6 6 6 5 Topoisomerase C-terminal repeat Toprim PF01751.22 EON31104.1 - 9.5e-30 102.9 0.0 2.8e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EON31104.1 - 3.2e-06 27.5 0.1 4.3e-05 23.9 0.0 3.0 2 1 0 2 2 2 1 Toprim domain HC2 PF07382.11 EON31104.1 - 3.3e-05 24.1 36.7 3.3e-05 24.1 36.7 2.3 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 SBP_bac_3 PF00497.20 EON31104.1 - 0.01 15.3 0.2 0.01 15.3 0.2 2.5 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 UTRA PF07702.13 EON31105.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 UTRA domain CSD PF00313.22 EON31106.1 - 5.6e-32 109.4 0.8 6.1e-32 109.3 0.8 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EON31106.1 - 1.6e-05 24.5 0.2 2.1e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain DEAD PF00270.29 EON31107.1 - 4.6e-19 68.9 0.0 8.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EON31107.1 - 1.2e-17 64.4 0.0 2.5e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EON31107.1 - 3.2e-11 43.6 0.0 7.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON31107.1 - 4.3e-05 23.6 0.0 6.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EON31107.1 - 0.00023 20.9 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF5615 PF18480.1 EON31107.1 - 0.084 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Tad PF13400.6 EON31108.1 - 4.5e-08 33.3 13.0 7.7e-08 32.5 13.0 1.4 1 0 0 1 1 1 1 Putative Flp pilus-assembly TadE/G-like DUF4342 PF14242.6 EON31109.1 - 0.039 14.0 10.0 0.81 9.7 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF4244 PF14029.6 EON31110.1 - 6.7e-24 83.1 3.0 6.7e-24 83.1 3.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4244) Glyoxalase PF00903.25 EON31111.1 - 2.8e-10 40.5 0.0 1.8e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON31111.1 - 1.8e-08 35.1 0.8 6.6e-08 33.3 0.8 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EON31111.1 - 0.005 17.1 0.2 1.6 9.0 0.0 2.1 1 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily T2SSF PF00482.23 EON31112.1 - 1.3e-15 57.5 0.2 1.8e-15 57.0 0.2 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F T2SSF PF00482.23 EON31113.1 - 0.0025 17.8 0.1 0.0079 16.1 0.1 1.9 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F T2SSE PF00437.20 EON31114.1 - 9.2e-68 228.2 0.0 1.1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 EON31114.1 - 0.00085 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EON31114.1 - 0.00089 19.5 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EON31114.1 - 0.0013 19.2 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 EON31114.1 - 0.0023 17.3 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EON31114.1 - 0.0036 17.6 0.2 0.0064 16.8 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EON31114.1 - 0.0048 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EON31114.1 - 0.0049 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EON31114.1 - 0.0053 15.7 0.0 0.0088 15.0 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EON31114.1 - 0.0061 17.0 0.4 0.018 15.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON31114.1 - 0.0069 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EON31114.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 EON31114.1 - 0.018 15.1 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 EON31114.1 - 0.019 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EON31114.1 - 0.025 15.1 0.8 0.039 14.4 0.8 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EON31114.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EON31114.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EON31114.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.14 EON31114.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Septin PF00735.18 EON31114.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA PF00004.29 EON31114.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EON31114.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IIGP PF05049.13 EON31114.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_ATPase PF09818.9 EON31114.1 - 0.2 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ParA PF10609.9 EON31115.1 - 0.00059 19.4 4.2 0.0044 16.5 4.2 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EON31115.1 - 0.0014 18.2 2.2 0.51 9.8 0.0 2.3 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 EON31115.1 - 0.0022 18.0 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EON31115.1 - 0.023 14.3 1.0 0.06 12.9 1.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EON31115.1 - 0.044 13.8 0.2 0.067 13.3 0.2 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EON31115.1 - 0.047 13.0 1.4 0.2 10.9 1.4 1.8 1 1 0 1 1 1 0 ATPase MipZ ArsA_ATPase PF02374.15 EON31115.1 - 0.38 9.9 0.5 0.64 9.1 0.5 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AMP-binding PF00501.28 EON31117.1 - 5.1e-94 315.3 0.0 6.4e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON31117.1 - 5e-25 88.3 0.7 1e-24 87.3 0.7 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EON31117.1 - 5.9e-20 70.9 1.1 5.9e-20 70.9 1.1 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Phage_holin_3_6 PF07332.11 EON31118.1 - 4.1e-29 100.9 6.8 4.7e-29 100.7 6.8 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SecY PF00344.20 EON31118.1 - 0.0039 16.5 0.7 0.0046 16.2 0.7 1.1 1 0 0 1 1 1 1 SecY translocase DUF2207 PF09972.9 EON31118.1 - 0.019 13.7 1.8 0.021 13.6 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 EON31118.1 - 0.029 14.1 0.7 0.035 13.8 0.7 1.1 1 0 0 1 1 1 0 Tetraspanin family PBP_N PF17093.5 EON31118.1 - 0.14 12.4 0.2 0.29 11.4 0.2 1.6 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus S_2TMBeta PF18153.1 EON31118.1 - 0.58 9.9 3.5 0.59 9.9 2.9 1.3 1 1 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Abhydrolase_1 PF00561.20 EON31119.1 - 2.9e-23 82.8 0.4 5.2e-23 82.0 0.4 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31119.1 - 9.8e-22 78.6 12.8 1.3e-21 78.2 12.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31119.1 - 3e-12 46.3 0.1 6.5e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EON31119.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.12 EON31119.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Trypsin_2 PF13365.6 EON31120.1 - 1.8e-23 84.1 0.9 4.6e-23 82.8 1.0 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Colicin_V PF02674.16 EON31120.1 - 5.3e-14 52.4 12.3 5.3e-14 52.4 12.3 1.6 2 0 0 2 2 2 1 Colicin V production protein Trypsin PF00089.26 EON31120.1 - 4.6e-10 39.7 0.0 9.8e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 EON31120.1 - 0.0059 15.3 0.3 0.016 13.9 0.2 1.6 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S3 PF00944.19 EON31120.1 - 0.052 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_S7 PF00949.21 EON31120.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease YtxH PF12732.7 EON31120.1 - 0.075 13.6 5.3 0.31 11.6 5.3 2.1 1 0 0 1 1 1 0 YtxH-like protein MerC PF03203.14 EON31120.1 - 7.8 7.0 10.4 0.55 10.7 5.5 1.6 2 0 0 2 2 2 0 MerC mercury resistance protein NUDIX PF00293.28 EON31121.1 - 1.3e-10 41.4 0.0 2.4e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain DUF2875 PF11394.8 EON31121.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) Redoxin PF08534.10 EON31122.1 - 1.5e-12 47.5 0.0 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EON31122.1 - 7.1e-08 32.4 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 EON31122.1 - 8.9e-07 28.8 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EON31122.1 - 0.049 13.9 0.0 0.09 13.1 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EON31122.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like HhH-GPD PF00730.25 EON31123.1 - 1.6e-22 80.0 0.0 2.8e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EON31123.1 - 2e-06 27.4 0.0 8.4e-06 25.4 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EON31123.1 - 1.7e-05 25.0 4.7 3.3e-05 24.1 4.7 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 EON31123.1 - 0.12 13.0 0.0 1.6 9.4 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain cNMP_binding PF00027.29 EON31125.1 - 1.4e-25 89.2 0.0 2.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 EON31125.1 - 2.5e-17 62.6 1.1 2.5e-17 62.6 1.1 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 EON31125.1 - 1.5e-05 24.6 0.1 3.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family GntR PF00392.21 EON31125.1 - 9.3e-05 22.0 0.8 0.00026 20.6 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 EON31125.1 - 0.00017 21.0 0.0 0.00041 19.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 EON31125.1 - 0.00029 20.7 1.2 0.0007 19.4 0.4 2.2 2 1 0 2 2 2 1 MarR family HTH_36 PF13730.6 EON31125.1 - 0.00067 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EON31125.1 - 0.0009 18.8 0.3 0.004 16.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 EON31125.1 - 0.0028 17.6 0.4 0.0091 16.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 EON31125.1 - 0.0036 17.0 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 EON31125.1 - 0.0044 16.8 0.2 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 EON31125.1 - 0.0091 16.0 0.1 0.075 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_28 PF13518.6 EON31125.1 - 0.015 15.4 0.5 0.063 13.4 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 EON31125.1 - 0.039 13.7 1.5 0.21 11.4 0.1 2.5 2 1 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 EON31125.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 MarR family HemN_C PF06969.16 EON31125.1 - 0.048 13.7 0.3 0.53 10.4 0.1 2.4 1 1 1 2 2 2 0 HemN C-terminal domain DUF977 PF06163.11 EON31125.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_AsnC-type PF13404.6 EON31125.1 - 0.083 12.7 2.6 2.8 7.9 0.1 2.9 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 EON31125.1 - 0.095 12.5 0.2 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 EON31125.1 - 0.097 13.0 4.4 0.12 12.7 0.2 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain TrmB PF01978.19 EON31125.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Lactamase_B PF00753.27 EON31126.1 - 6.7e-17 62.2 6.9 2e-16 60.6 6.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON31126.1 - 5.3e-08 32.6 1.7 2.2e-07 30.6 1.7 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EON31126.1 - 2.7e-06 27.2 0.1 6.2e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 EON31126.1 - 0.0034 17.3 0.0 0.007 16.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Band_7 PF01145.25 EON31127.1 - 1.9e-19 70.4 0.9 1.9e-19 70.4 0.9 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 EON31127.1 - 0.0037 17.4 6.5 0.0037 17.4 6.5 3.5 1 1 2 3 3 3 1 Flotillin NfeD PF01957.18 EON31128.1 - 0.031 14.6 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding LMWPc PF01451.21 EON31130.1 - 9.5e-15 55.2 0.1 1.5e-14 54.6 0.1 1.5 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyoxalase PF00903.25 EON31131.1 - 4.2e-08 33.4 0.0 5.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON31131.1 - 0.00054 20.7 0.0 0.00095 19.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EON31131.1 - 0.0028 17.9 0.0 0.36 11.1 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HTH_5 PF01022.20 EON31132.1 - 9.1e-12 44.7 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON31132.1 - 1.7e-10 40.8 0.4 4.3e-10 39.5 0.2 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EON31132.1 - 0.00016 21.6 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EON31132.1 - 0.00024 20.6 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding FaeA PF04703.12 EON31132.1 - 0.00032 21.0 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 FaeA-like protein HTH_34 PF13601.6 EON31132.1 - 0.025 14.8 0.0 0.074 13.2 0.0 1.7 1 1 1 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.19 EON31132.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EON31132.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.4 1 1 0 1 1 1 0 Transcriptional regulator DUF3562 PF12085.8 EON31133.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) DUF899 PF05988.12 EON31135.1 - 2e-60 204.0 0.1 2.4e-60 203.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Response_reg PF00072.24 EON31136.1 - 2.7e-28 98.4 0.0 5.1e-28 97.5 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 EON31136.1 - 1e-23 83.2 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EON31136.1 - 0.0046 17.3 0.0 0.0067 16.8 0.0 1.4 1 1 0 1 1 1 1 Flagellar regulatory protein FleQ HATPase_c PF02518.26 EON31137.1 - 6.9e-27 94.2 0.0 1.1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON31137.1 - 2.4e-17 62.7 0.2 6e-17 61.4 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EON31137.1 - 6.1e-13 48.9 0.4 6.1e-13 48.9 0.4 2.6 3 0 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 EON31137.1 - 0.0043 17.0 0.6 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EON31137.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YcbB PF08664.10 EON31137.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 YcbB domain LapA_dom PF06305.11 EON31137.1 - 0.85 9.5 4.0 4.8 7.1 0.3 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DpnII PF04556.12 EON31138.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 DpnII restriction endonuclease MethyltransfD12 PF02086.15 EON31139.1 - 2.6e-13 50.3 0.0 3.1e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.15 EON31139.1 - 0.005 16.5 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 HIT PF01230.23 EON31140.1 - 2.6e-18 66.5 0.0 3.4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EON31140.1 - 2.9e-07 31.0 0.0 3.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.29 EON31141.1 - 7.4e-15 55.2 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON31141.1 - 3.7e-12 46.6 0.0 5.7e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON31141.1 - 7.6e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pribosyltran PF00156.27 EON31141.1 - 0.00036 20.1 0.1 0.00073 19.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HEM4 PF02602.15 EON31141.1 - 0.0049 16.3 4.3 0.026 13.9 0.3 3.0 4 0 0 4 4 4 1 Uroporphyrinogen-III synthase HemD RecQ_Zn_bind PF16124.5 EON31141.1 - 0.016 16.0 0.3 0.03 15.0 0.3 1.4 1 0 0 1 1 1 0 RecQ zinc-binding AAA_16 PF13191.6 EON31141.1 - 0.045 14.1 0.1 0.21 12.0 0.1 2.3 1 0 0 1 1 1 0 AAA ATPase domain Baculo_LEF5_C PF11792.8 EON31141.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Glycos_transf_2 PF00535.26 EON31142.1 - 3e-19 69.4 0.0 4.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 EON31142.1 - 5.6e-08 33.0 9.3 1.1e-07 32.0 9.3 1.5 1 0 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 EON31142.1 - 0.0002 21.3 0.3 0.00035 20.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EON31142.1 - 0.022 15.2 0.2 0.051 14.1 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Polysacc_synt_C PF14667.6 EON31142.1 - 0.7 10.0 7.8 1.1 9.3 7.8 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PMT_2 PF13231.6 EON31143.1 - 3.4e-33 115.1 13.7 3.4e-33 115.1 13.7 3.9 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GARS_A PF01071.19 EON31144.1 - 1.4e-65 220.8 0.0 2.1e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EON31144.1 - 1.5e-30 105.8 1.0 3.3e-30 104.7 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EON31144.1 - 9.4e-28 96.3 1.0 2.6e-27 94.9 1.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 EON31144.1 - 0.00099 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EON31144.1 - 0.0032 17.0 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Esterase PF00756.20 EON31145.1 - 5.2e-08 32.8 0.1 5.1e-07 29.6 0.1 2.4 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EON31145.1 - 0.00045 19.6 0.1 0.0021 17.4 0.2 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON31145.1 - 0.0042 16.8 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31145.1 - 0.005 17.5 5.3 0.005 17.5 5.3 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EON31145.1 - 0.051 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EON31145.1 - 0.092 12.3 0.2 0.93 9.0 0.2 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EON31145.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Asp2 PF16929.5 EON31145.1 - 0.33 9.9 0.1 0.45 9.4 0.1 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter dCMP_cyt_deam_1 PF00383.23 EON31146.1 - 1.3e-17 63.5 0.0 1.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EON31146.1 - 8.1e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EON31146.1 - 4.6e-05 23.5 0.0 6.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 EON31146.1 - 0.00016 21.8 0.5 0.38 10.8 0.2 2.4 1 1 1 2 2 2 2 Bd3614-like deaminase NAD1 PF18778.1 EON31146.1 - 0.0018 18.4 0.0 0.0023 18.0 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 EON31146.1 - 0.0018 18.3 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 EON31146.1 - 0.0044 16.9 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 EON31146.1 - 0.0096 16.0 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 EON31146.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 APOBEC3 Toprim_C_rpt PF13368.6 EON31146.1 - 0.038 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat NAD2 PF18782.1 EON31146.1 - 0.09 12.9 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 TetR_C_31 PF17940.1 EON31148.1 - 1.1e-13 51.3 6.0 1.1e-13 51.3 6.0 2.1 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON31148.1 - 3.1e-07 30.1 0.3 8e-07 28.8 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Ntox3 PF15536.6 EON31149.1 - 0.11 12.6 0.2 2.6 8.1 0.1 2.0 2 0 0 2 2 2 0 Bacterial toxin 3 YbgT_YccB PF08173.11 EON31149.1 - 0.45 10.7 2.3 0.78 9.9 2.3 1.4 1 0 0 1 1 1 0 Membrane bound YbgT-like protein Lyase_1 PF00206.20 EON31150.1 - 9.4e-21 74.5 1.5 1.8e-20 73.6 0.7 1.9 2 1 0 2 2 2 1 Lyase ADSL_C PF10397.9 EON31150.1 - 1.3e-13 51.3 2.0 1.3e-13 51.3 2.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus TPR_6 PF13174.6 EON31150.1 - 0.16 12.6 0.6 60 4.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PE PF00934.20 EON31150.1 - 5.3 7.4 11.3 0.22 11.8 2.6 3.1 3 0 0 3 3 3 0 PE family Rdx PF10262.9 EON31151.1 - 1.2e-29 102.3 0.0 1.3e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Rdx family SAICAR_synt PF01259.18 EON31152.1 - 3e-100 335.0 0.0 3.6e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase DUF1830 PF08865.11 EON31152.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Peptidase_S9_N PF02897.15 EON31153.1 - 1e-101 340.8 0.0 1.2e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EON31153.1 - 3e-63 213.1 0.0 5e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EON31153.1 - 0.0039 15.9 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EON31153.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 EON31154.1 - 1.3e-60 205.2 88.9 1.2e-50 172.4 56.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EON31154.1 - 1.7e-10 40.1 35.0 3e-05 22.8 8.6 3.5 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 EON31154.1 - 1.5e-05 24.0 14.2 1.5e-05 24.0 14.2 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter MarR_2 PF12802.7 EON31155.1 - 4.7e-14 52.0 0.3 1.3e-13 50.6 0.2 1.8 2 0 0 2 2 2 1 MarR family MarR PF01047.22 EON31155.1 - 1.4e-11 44.1 0.0 3.7e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EON31155.1 - 7.8e-10 39.1 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 EON31155.1 - 2.9e-06 27.2 0.0 8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EON31155.1 - 5.5e-05 22.9 0.1 0.00013 21.6 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EON31155.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Dimerisation2 PF16864.5 EON31155.1 - 0.0096 15.9 0.2 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Dimerisation domain HTH_AsnC-type PF13404.6 EON31155.1 - 0.014 15.2 0.1 0.05 13.4 0.1 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TrmB PF01978.19 EON31155.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EON31155.1 - 0.079 13.3 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.20 EON31155.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GSHPx PF00255.19 EON31156.1 - 2.7e-35 120.2 0.0 3.6e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 EON31156.1 - 0.00022 21.0 0.0 0.00084 19.1 0.0 1.8 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EON31156.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family PurS PF02700.14 EON31157.1 - 1.3e-23 82.9 0.0 1.5e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase GATase_5 PF13507.6 EON31158.1 - 1.1e-37 129.5 0.0 1.9e-37 128.8 0.0 1.3 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 EON31158.1 - 5.8e-08 32.6 0.0 8.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EON31158.1 - 2.9e-07 30.4 0.1 6.1e-07 29.4 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EON31158.1 - 2.6e-06 27.4 0.1 3.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 EON31158.1 - 0.00036 20.4 0.9 0.0018 18.0 0.9 1.9 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 EON31158.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Peptidase_M18 PF02127.15 EON31159.1 - 6.2e-130 433.8 0.0 7.3e-130 433.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EON31159.1 - 1.8e-05 24.0 0.0 0.0011 18.1 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase SLT_2 PF13406.6 EON31160.1 - 3.3e-10 39.7 1.0 1.2e-08 34.6 0.1 2.6 2 1 0 3 3 3 2 Transglycosylase SLT domain SLT PF01464.20 EON31160.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain PQQ_2 PF13360.6 EON31161.1 - 1.6e-07 31.2 3.7 9.2e-05 22.1 1.7 3.2 1 1 1 2 2 2 2 PQQ-like domain IceA2 PF05862.11 EON31161.1 - 0.1 12.5 0.9 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein DUF1772 PF08592.11 EON31162.1 - 3.1e-14 53.5 12.0 3.8e-14 53.2 12.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3688 PF12461.8 EON31162.1 - 0.52 8.7 0.7 0.55 8.6 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) Glyoxalase_6 PF18029.1 EON31163.1 - 3.3e-22 79.3 14.2 2.8e-09 37.7 0.7 3.7 3 1 0 3 3 3 3 Glyoxalase-like domain Glyoxalase PF00903.25 EON31163.1 - 6.8e-19 68.3 0.4 1.4e-05 25.3 0.0 5.1 3 2 0 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON31163.1 - 0.00016 21.9 5.9 1.9 8.8 0.2 5.3 4 2 0 4 4 4 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Adhesin_P1_N PF18652.1 EON31163.1 - 0.025 14.6 0.6 0.062 13.3 0.6 1.6 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain DUF4377 PF14302.6 EON31163.1 - 0.11 12.6 0.0 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4377) Sigma70_r2 PF04542.14 EON31164.1 - 3.6e-11 42.7 0.9 5.6e-11 42.1 0.9 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON31164.1 - 4e-10 39.2 0.0 5.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON31164.1 - 2e-06 27.2 0.0 2.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Abhydrolase_1 PF00561.20 EON31165.1 - 3.6e-09 36.7 0.0 0.0036 17.0 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31165.1 - 3.9e-09 37.4 11.7 4.9e-09 37.1 11.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family TetR_N PF00440.23 EON31166.1 - 2.9e-17 62.2 0.3 8.7e-17 60.7 0.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DHNA PF04038.12 EON31166.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase GMC_oxred_N PF00732.19 EON31167.1 - 1.2e-70 238.2 0.0 1.5e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON31167.1 - 1.4e-39 135.9 0.0 2.2e-38 132.0 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EON31167.1 - 0.00012 21.3 0.4 0.00022 20.4 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EON31167.1 - 0.00098 18.3 1.5 0.37 9.8 0.4 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EON31167.1 - 0.0015 18.7 0.1 0.0059 16.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON31167.1 - 0.0029 17.2 0.9 0.016 14.8 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON31167.1 - 0.023 14.0 0.1 0.043 13.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EON31167.1 - 0.041 13.1 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 EON31168.1 - 1.1e-155 518.6 0.0 1.3e-155 518.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BCCT PF02028.17 EON31169.1 - 5.8e-168 559.3 28.3 6.8e-168 559.1 28.3 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter TrbC PF04956.13 EON31169.1 - 0.037 14.3 0.5 0.037 14.3 0.5 4.1 4 1 0 4 4 4 0 TrbC/VIRB2 family Glyoxalase_6 PF18029.1 EON31170.1 - 1.9e-18 67.2 0.0 8.6e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 EON31170.1 - 1.2e-09 38.5 0.1 4.3e-05 23.7 0.1 2.9 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON31170.1 - 0.0012 19.0 0.1 9.3 6.6 0.0 3.2 2 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_2 PF07724.14 EON31171.1 - 4e-52 176.8 0.0 3.1e-50 170.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 EON31171.1 - 1.6e-36 124.2 7.9 3.2e-18 65.6 0.9 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 EON31171.1 - 2.4e-35 120.6 1.0 6e-35 119.3 1.0 1.7 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 EON31171.1 - 7.5e-26 90.0 0.5 2.7e-25 88.2 0.5 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EON31171.1 - 1.7e-22 80.2 0.0 5.7e-12 46.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON31171.1 - 6.8e-18 65.0 0.0 9e-11 41.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON31171.1 - 6.9e-13 49.3 2.6 1.9e-06 28.4 0.0 4.3 2 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EON31171.1 - 1.7e-10 40.8 0.1 1.6e-07 31.2 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EON31171.1 - 6e-09 36.3 0.1 0.0064 16.8 0.1 4.5 3 1 0 3 3 3 2 AAA domain TniB PF05621.11 EON31171.1 - 2.2e-07 30.5 0.1 0.00027 20.4 0.0 3.9 2 2 1 3 3 3 1 Bacterial TniB protein UVR PF02151.19 EON31171.1 - 1.2e-06 28.1 6.7 3e-06 26.8 6.7 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif ATPase_2 PF01637.18 EON31171.1 - 2.2e-06 27.8 3.4 0.031 14.2 0.1 4.3 3 2 1 4 4 4 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EON31171.1 - 1.4e-05 24.9 0.0 0.11 12.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EON31171.1 - 9.2e-05 23.0 1.9 0.19 12.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain RuvB_N PF05496.12 EON31171.1 - 9.3e-05 22.2 0.2 2 8.1 0.0 4.4 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EON31171.1 - 0.00011 22.6 0.1 0.68 10.4 0.0 3.1 3 0 0 3 3 2 2 RNA helicase RsgA_GTPase PF03193.16 EON31171.1 - 0.00012 22.1 0.1 0.45 10.4 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 EON31171.1 - 0.00043 20.3 0.0 0.47 10.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EON31171.1 - 0.00051 20.2 0.1 2.1 8.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_3 PF07726.11 EON31171.1 - 0.00069 19.5 0.0 0.5 10.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EON31171.1 - 0.0012 18.6 0.2 1.4 8.6 0.1 3.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EON31171.1 - 0.0015 18.0 0.0 4.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EON31171.1 - 0.0017 18.3 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain DNA_pol3_delta2 PF13177.6 EON31171.1 - 0.002 17.9 0.0 0.087 12.6 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.13 EON31171.1 - 0.0028 16.8 0.0 2 7.5 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EON31171.1 - 0.0029 17.9 0.6 5 7.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EON31171.1 - 0.0046 16.7 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 EON31171.1 - 0.005 17.0 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EON31171.1 - 0.0069 15.9 0.1 1.6 8.2 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region ResIII PF04851.15 EON31171.1 - 0.0097 15.9 0.0 5.2 7.0 0.0 3.9 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EON31171.1 - 0.018 14.4 0.0 1.9 7.7 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EON31171.1 - 0.019 15.3 0.3 0.6 10.4 0.2 3.2 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EON31171.1 - 0.02 14.5 0.0 2.9 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EON31171.1 - 0.021 15.3 7.9 0.16 12.5 0.0 3.3 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON31171.1 - 0.027 14.2 0.0 2.8 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF99 PF01949.16 EON31171.1 - 0.032 13.7 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 Torsin PF06309.11 EON31171.1 - 0.033 14.3 0.0 0.62 10.2 0.0 2.8 3 0 0 3 3 3 0 Torsin TIP49 PF06068.13 EON31171.1 - 0.043 13.0 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 TIP49 P-loop domain NTPase_1 PF03266.15 EON31171.1 - 0.043 13.7 0.2 7.9 6.4 0.1 3.0 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.27 EON31171.1 - 0.056 14.0 0.0 6.3 7.3 0.0 2.7 2 0 0 2 2 2 0 ABC transporter CbiA PF01656.23 EON31171.1 - 0.12 12.4 0.0 20 5.2 0.0 2.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ECH_1 PF00378.20 EON31172.1 - 3.7e-48 164.0 0.0 6.1e-48 163.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31172.1 - 1.7e-28 100.1 0.0 5.1e-28 98.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HNH_5 PF14279.6 EON31173.1 - 1.6e-10 40.7 0.1 2.2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EON31173.1 - 4.6e-10 39.5 0.0 7.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EON31173.1 - 6e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 HNH endonuclease DUF305 PF03713.13 EON31174.1 - 2.8e-36 124.9 1.6 3.4e-36 124.7 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) LVIVD PF08309.11 EON31175.1 - 0.00011 21.5 0.3 0.53 9.7 0.1 4.2 4 0 0 4 4 4 2 LVIVD repeat PD40 PF07676.12 EON31175.1 - 0.17 11.9 1.9 13 5.9 0.5 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1972 PF09314.11 EON31177.1 - 7.7e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1972) Glyco_trans_4_4 PF13579.6 EON31177.1 - 2.9e-08 34.3 1.1 2.9e-08 34.3 1.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EON31177.1 - 1.8e-06 28.4 0.0 3.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON31177.1 - 0.00011 22.2 1.2 0.00056 19.9 0.3 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EON31177.1 - 0.00068 20.0 0.2 0.0054 17.1 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EON31177.1 - 0.00084 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_31 PF13614.6 EON31179.1 - 2.2e-11 44.0 0.0 4.9e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EON31179.1 - 2.3e-11 43.9 0.0 3.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EON31179.1 - 1.9e-07 30.8 0.8 2.1e-06 27.4 0.8 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_26 PF13500.6 EON31179.1 - 2.9e-05 24.0 0.9 0.043 13.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 EON31179.1 - 0.00025 20.8 0.0 0.00072 19.2 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MipZ PF09140.11 EON31179.1 - 0.004 16.5 0.0 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ CLP1_P PF16575.5 EON31179.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 EON31179.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Fer4_NifH PF00142.18 EON31179.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FTHFS PF01268.19 EON31179.1 - 0.14 10.4 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase ArsA_ATPase PF02374.15 EON31179.1 - 0.15 11.2 0.9 0.4 9.8 0.3 2.0 2 1 1 3 3 3 0 Anion-transporting ATPase Lipase_GDSL_2 PF13472.6 EON31182.1 - 3.9e-18 66.5 1.0 4.6e-18 66.2 1.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON31182.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Response_reg PF00072.24 EON31183.1 - 4.8e-08 33.1 0.0 7.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON31183.1 - 7.2e-07 28.7 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON31183.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 EON31183.1 - 0.00028 20.8 0.0 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EON31183.1 - 0.0024 18.0 0.3 0.041 14.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 EON31183.1 - 0.0093 16.0 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON31183.1 - 0.039 13.7 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HATPase_c_2 PF13581.6 EON31184.1 - 1.3e-07 31.6 0.1 2.8e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 EON31184.1 - 7.9e-06 26.4 0.1 1.9e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EON31184.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2838 PF10998.8 EON31184.1 - 0.42 10.9 5.5 0.79 10.0 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) GerE PF00196.19 EON31186.1 - 5.8e-09 35.4 0.0 8.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_30 PF13556.6 EON31186.1 - 3e-05 23.7 0.1 5.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Sigma70_r4_2 PF08281.12 EON31186.1 - 0.11 12.2 0.2 0.25 11.0 0.1 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 CM1 PF03026.15 EON31186.1 - 0.15 11.4 0.1 13 5.1 0.0 2.0 1 1 1 2 2 2 0 Influenza C virus M1 protein Lipase_GDSL_2 PF13472.6 EON31187.1 - 7.2e-17 62.3 0.6 8.7e-17 62.1 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON31187.1 - 0.00018 21.6 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF222 PF02720.17 EON31188.1 - 1.6e-34 119.8 8.6 1.6e-34 119.8 8.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF222) HNH PF01844.23 EON31188.1 - 0.09 13.0 0.5 0.17 12.0 0.5 1.5 1 0 0 1 1 1 0 HNH endonuclease PE-PPE PF08237.11 EON31189.1 - 3.5e-09 36.5 0.1 5.5e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain NUDIX PF00293.28 EON31191.1 - 4.7e-14 52.6 0.0 7.1e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain YceI PF04264.13 EON31192.1 - 4.3e-47 160.4 1.1 4.9e-47 160.2 1.1 1.0 1 0 0 1 1 1 1 YceI-like domain Guanylate_cyc PF00211.20 EON31193.1 - 9.6e-23 80.7 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 EON31193.1 - 3e-11 43.5 0.0 8.6e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 HAMP domain adh_short PF00106.25 EON31194.1 - 3.2e-20 72.4 1.6 3.9e-19 68.9 1.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31194.1 - 2.7e-14 53.3 0.9 1e-13 51.4 0.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON31194.1 - 0.00019 21.4 0.5 0.00025 21.0 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EON31194.1 - 0.0005 20.0 1.3 0.001 19.0 1.3 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EON31194.1 - 0.0017 18.6 0.3 0.0028 17.9 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EON31194.1 - 0.051 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 EON31194.1 - 0.055 13.5 1.9 0.067 13.2 0.9 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2OG-FeII_Oxy_2 PF13532.6 EON31198.1 - 6.8e-14 52.5 0.0 1.2e-13 51.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GIY-YIG PF01541.24 EON31199.1 - 6.7e-14 51.9 0.0 7.6e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 EON31199.1 - 2.4e-06 28.0 0.0 2.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EON31199.1 - 0.07 13.8 0.4 0.19 12.4 0.4 1.7 1 1 1 2 2 2 0 Meiotically up-regulated gene 113 GMC_oxred_C PF05199.13 EON31200.1 - 4.6e-15 56.4 0.2 8.6e-15 55.5 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EON31200.1 - 4e-14 52.7 0.0 2.7e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EON31200.1 - 9.8e-10 38.5 0.3 0.00081 19.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON31200.1 - 7e-09 35.2 2.8 4e-06 26.2 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EON31200.1 - 1.3e-06 27.9 0.0 3.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON31200.1 - 5.1e-06 26.6 0.1 1.6e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_10 PF13237.6 EON31200.1 - 0.0021 18.2 0.4 0.0038 17.3 0.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EON31200.1 - 0.0033 17.5 0.1 0.006 16.7 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain GIDA PF01134.22 EON31200.1 - 0.0045 16.1 0.0 0.034 13.2 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Fer4_7 PF12838.7 EON31200.1 - 0.0046 17.5 1.3 0.0083 16.7 1.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EON31200.1 - 0.013 15.9 0.1 0.023 15.1 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain HI0933_like PF03486.14 EON31200.1 - 0.014 14.2 0.1 0.025 13.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Fer4 PF00037.27 EON31200.1 - 0.015 15.1 6.0 0.026 14.3 6.0 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Pyr_redox PF00070.27 EON31200.1 - 0.023 15.2 0.0 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON31200.1 - 0.036 13.3 0.1 0.063 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Fer4_17 PF13534.6 EON31200.1 - 0.062 13.9 0.2 0.11 13.1 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON31200.1 - 0.13 12.9 3.7 0.23 12.0 3.7 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_oxidored PF12831.7 EON31200.1 - 0.13 11.6 0.2 0.22 10.8 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_6 PF12837.7 EON31200.1 - 0.26 11.5 7.3 0.46 10.6 7.3 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 EON31200.1 - 0.34 12.0 7.1 0.56 11.3 7.1 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_2 PF12797.7 EON31200.1 - 1.4 9.2 6.3 2.6 8.3 6.3 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain K_oxygenase PF13434.6 EON31201.1 - 4.8e-16 58.8 0.1 7.5e-13 48.3 0.0 3.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EON31201.1 - 9.4e-15 54.6 0.0 8.1e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON31201.1 - 3.3e-13 48.9 0.0 6.6e-11 41.3 0.0 2.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON31201.1 - 5e-13 48.9 0.0 6.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON31201.1 - 1.1e-06 28.7 0.2 5.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON31201.1 - 6.6e-06 26.2 1.9 0.025 14.6 0.1 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EON31201.1 - 0.022 14.0 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EON31201.1 - 0.089 11.8 0.1 0.71 8.9 0.1 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EON31201.1 - 0.11 11.8 0.1 1.6 7.9 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 EON31201.1 - 0.71 9.4 8.2 12 5.4 0.6 3.4 1 1 2 3 3 3 0 FAD dependent oxidoreductase TetR_N PF00440.23 EON31202.1 - 2.7e-14 52.7 0.9 5.4e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_35 PF13693.6 EON31202.1 - 0.13 12.3 0.0 0.75 9.9 0.0 2.1 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Bac_luciferase PF00296.20 EON31203.1 - 1.4e-55 188.9 5.8 3.2e-55 187.8 5.8 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase Aminotran_1_2 PF00155.21 EON31204.1 - 5e-60 203.6 0.0 5.6e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EON31204.1 - 3e-07 29.7 0.0 4.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EON31204.1 - 1.1e-06 27.5 0.0 1.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EON31204.1 - 0.0021 17.4 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EON31204.1 - 0.016 13.9 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 EON31204.1 - 0.021 14.2 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 EON31205.1 - 3.5e-38 131.5 0.0 4.6e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON31205.1 - 9.8e-22 77.5 0.0 1.3e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EON31205.1 - 5e-05 22.8 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EON31205.1 - 0.00021 21.3 0.0 0.014 15.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON31205.1 - 0.00091 18.1 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pex14_N PF04695.13 EON31205.1 - 5.3 7.7 8.7 0.2 12.3 1.2 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ERCC3_RAD25_C PF16203.5 EON31206.1 - 7.5e-47 159.6 0.0 1.1e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EON31206.1 - 3.6e-43 146.7 0.5 6.5e-43 145.9 0.5 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON31206.1 - 3.7e-13 49.8 0.0 6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EON31206.1 - 2.6e-12 47.1 0.0 4.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EON31206.1 - 0.00021 20.1 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EON31206.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2236 PF09995.9 EON31207.1 - 1.6e-33 116.8 1.7 2.3e-33 116.3 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Helicase_C_3 PF13625.6 EON31208.1 - 6.8e-38 129.7 1.9 8.5e-38 129.4 0.5 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GntR PF00392.21 EON31208.1 - 0.026 14.2 1.2 1 9.1 0.1 3.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family PHP_C PF13263.6 EON31208.1 - 0.054 13.2 0.1 0.27 11.0 0.1 2.3 2 0 0 2 2 2 0 PHP-associated Amidohydro_1 PF01979.20 EON31209.1 - 3.1e-30 105.7 0.0 3.8e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON31209.1 - 7.5e-13 48.8 0.8 9.2e-08 32.0 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 EON31209.1 - 0.036 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain TatD_DNase PF01026.21 EON31209.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 2 0 0 2 2 2 0 TatD related DNase Transp_cyt_pur PF02133.15 EON31210.1 - 3.7e-86 289.6 39.0 4.3e-86 289.4 39.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4051 PF13260.6 EON31210.1 - 0.14 11.9 0.6 0.54 10.0 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF3165 PF11364.8 EON31210.1 - 0.62 10.5 0.0 0.62 10.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3165) Amdase PF17645.1 EON31211.1 - 0.0019 17.8 0.3 0.0034 17.0 0.3 1.4 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 EON31211.1 - 0.002 18.0 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 EON31211.1 - 0.022 14.1 0.3 0.59 9.5 0.1 2.3 2 0 0 2 2 2 0 AroM protein MDMPI_N PF11716.8 EON31212.1 - 3.8e-13 50.3 11.7 7.3e-13 49.4 11.7 1.5 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON31212.1 - 0.19 12.2 5.5 0.28 11.7 5.5 1.5 1 1 0 1 1 1 0 DinB superfamily Abhydrolase_1 PF00561.20 EON31213.1 - 3e-15 56.6 0.0 1.3e-09 38.1 0.5 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31213.1 - 1.7e-13 51.7 8.3 2.4e-13 51.2 8.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31213.1 - 6.2e-11 42.0 2.0 5e-07 29.2 1.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EON31213.1 - 0.00071 19.3 0.0 0.0027 17.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 EON31213.1 - 0.0087 16.2 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain HxlR PF01638.17 EON31216.1 - 7.7e-29 99.4 0.0 1e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EON31216.1 - 0.012 15.5 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_Crp_2 PF13545.6 EON31216.1 - 0.022 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 EON31216.1 - 0.05 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 MarR family CMAS PF02353.20 EON31217.1 - 1.9e-94 316.0 0.0 2.2e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EON31217.1 - 5.2e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON31217.1 - 2e-11 44.0 0.0 3.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON31217.1 - 4.7e-11 43.3 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON31217.1 - 2.5e-07 31.4 0.0 6.2e-07 30.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON31217.1 - 0.00041 20.2 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EON31217.1 - 0.005 16.5 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 EON31217.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EON31217.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EON31217.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 EON31217.1 - 0.22 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAD_binding_4 PF01565.23 EON31218.1 - 1.3e-10 41.1 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Polyketide_cyc2 PF10604.9 EON31219.1 - 1.3e-17 64.4 0.8 1.6e-17 64.1 0.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PseudoU_synth_2 PF00849.22 EON31220.1 - 1e-22 80.9 0.0 1.3e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Imm10 PF15588.6 EON31221.1 - 6.4e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 Immunity protein 10 YbaB_DNA_bd PF02575.16 EON31222.1 - 2.9e-30 104.3 0.6 3.4e-30 104.1 0.6 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Toprim_4 PF13662.6 EON31223.1 - 2.2e-23 82.5 0.0 4.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 EON31223.1 - 3.4e-12 45.7 4.7 6.8e-12 44.7 4.7 1.6 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 EON31223.1 - 5.1e-11 42.7 0.0 8.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain HHH_5 PF14520.6 EON31223.1 - 0.0072 16.9 0.0 0.073 13.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 EON31223.1 - 0.0098 15.7 0.7 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Toprim_2 PF13155.6 EON31223.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Toprim-like zn-ribbon_14 PF16503.5 EON31223.1 - 0.16 11.5 2.8 0.31 10.6 2.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon Abhydrolase_1 PF00561.20 EON31224.1 - 2.7e-16 60.0 0.0 3.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EON31224.1 - 7.9e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein AAA_16 PF13191.6 EON31225.1 - 1.6e-05 25.4 0.0 2.3e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 EON31225.1 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 EON31225.1 - 0.00044 20.4 0.1 0.0024 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON31225.1 - 0.00046 20.1 0.0 0.0006 19.8 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EON31225.1 - 0.0023 18.2 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON31225.1 - 0.0025 18.4 0.1 0.015 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EON31225.1 - 0.0053 16.5 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 EON31225.1 - 0.0068 15.4 0.1 0.0095 14.9 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 EON31225.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase APS_kinase PF01583.20 EON31225.1 - 0.013 15.5 0.1 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_29 PF13555.6 EON31225.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EON31225.1 - 0.018 15.5 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EON31225.1 - 0.067 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EON31225.1 - 0.097 12.4 0.1 0.2 11.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EON31225.1 - 0.098 12.7 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EON31225.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 EON31225.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 EON31225.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ParA PF10609.9 EON31225.1 - 0.24 10.8 0.4 0.35 10.3 0.4 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase UDG PF03167.19 EON31226.1 - 6.1e-25 88.0 0.0 7.8e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GATase_3 PF07685.14 EON31227.1 - 3.4e-35 121.4 0.0 4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Glyco_tran_WecB PF03808.13 EON31227.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DJ-1_PfpI PF01965.24 EON31227.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family DUF1727 PF08353.10 EON31228.1 - 5e-24 84.4 0.0 1.9e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1727) Mur_ligase_M PF08245.12 EON31228.1 - 2.6e-14 53.7 0.0 1.2e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Abhydrolase_3 PF07859.13 EON31229.1 - 6.1e-75 251.7 0.1 1e-74 251.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EON31229.1 - 4.2e-05 22.6 0.2 9e-05 21.5 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EON31229.1 - 0.0055 16.2 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Say1_Mug180 PF10340.9 EON31229.1 - 0.022 13.6 0.0 0.064 12.1 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_5 PF12695.7 EON31229.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EON31229.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 EON31229.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) EamA PF00892.20 EON31230.1 - 2.3e-32 112.0 35.4 1.1e-16 61.3 8.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EON31230.1 - 0.00063 18.8 1.2 0.00063 18.8 1.2 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF4112 PF13430.6 EON31230.1 - 0.078 13.3 1.7 0.22 11.8 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Multi_Drug_Res PF00893.19 EON31230.1 - 1.4 9.6 9.3 0.28 11.9 3.0 2.8 3 0 0 3 3 3 0 Small Multidrug Resistance protein TPT PF03151.16 EON31230.1 - 2.9 7.2 7.5 0.39 10.0 0.4 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Thioredoxin PF00085.20 EON31231.1 - 4e-24 84.6 0.0 4.7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EON31231.1 - 3.1e-08 34.0 0.0 6.1e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EON31231.1 - 3.7e-06 27.2 0.0 5.7e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EON31231.1 - 1.5e-05 24.8 0.0 1.8e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EON31231.1 - 0.00011 21.6 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EON31231.1 - 0.0044 16.7 0.0 0.0082 15.9 0.0 1.5 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 EON31231.1 - 0.005 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EON31231.1 - 0.034 14.3 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like LysR_substrate PF03466.20 EON31232.1 - 1.5e-24 86.5 10.1 2.7e-24 85.7 10.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EON31232.1 - 1.5e-16 60.1 0.9 3.3e-16 59.0 0.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 EON31232.1 - 0.00018 21.3 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON31232.1 - 0.0004 20.4 2.1 0.0026 17.8 0.2 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.7 EON31232.1 - 0.00065 19.5 0.5 0.00065 19.5 0.5 3.7 4 1 0 4 4 4 1 MarR family HTH_28 PF13518.6 EON31232.1 - 0.00066 19.7 1.3 0.0032 17.6 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON31232.1 - 0.0013 18.5 0.5 0.0043 16.8 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 EON31232.1 - 0.052 13.1 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 EON31232.1 - 0.094 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.10 EON31232.1 - 3.7 7.4 6.9 2.9 7.8 0.2 3.6 4 0 0 4 4 4 0 IclR helix-turn-helix domain Acyl-CoA_dh_1 PF00441.24 EON31233.1 - 1.9e-43 148.2 0.1 3.1e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31233.1 - 1.2e-31 109.7 0.1 2.2e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31233.1 - 9.6e-26 89.8 0.2 2.3e-25 88.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31233.1 - 9.6e-12 45.3 0.1 1.8e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_C_24 PF17932.1 EON31234.1 - 2.9e-24 85.5 0.0 4.2e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON31234.1 - 4.6e-14 51.9 0.1 8.4e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_4 PF08359.11 EON31234.1 - 4.4e-05 23.6 0.0 6.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_17 PF17922.1 EON31234.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 EON31234.1 - 0.0031 17.8 0.3 0.0092 16.3 0.3 1.9 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 EON31234.1 - 0.0044 17.1 0.0 0.012 15.6 0.0 1.7 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 EON31234.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 EON31234.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_7 PF02796.15 EON31234.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Thiolase_N PF00108.23 EON31235.1 - 7.8e-63 212.3 0.0 1.3e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON31235.1 - 3.3e-40 136.5 0.0 6.8e-40 135.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON31235.1 - 9.2e-05 22.1 2.1 9.2e-05 22.1 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ABM PF03992.16 EON31236.1 - 8.6e-19 67.4 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Bac_luciferase PF00296.20 EON31237.1 - 1.2e-29 103.8 1.0 1.6e-29 103.3 1.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase HMGL-like PF00682.19 EON31238.1 - 5.1e-79 265.6 0.0 1.3e-78 264.2 0.0 1.7 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EON31238.1 - 1.1e-31 109.5 0.5 2.2e-31 108.5 0.5 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sugar_tr PF00083.24 EON31239.1 - 3.5e-30 105.3 25.2 5e-29 101.5 25.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON31239.1 - 1.2e-21 77.1 51.7 1.2e-21 77.1 51.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UL42 PF17638.2 EON31239.1 - 0.053 13.5 0.3 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 HCMV UL42 PDGLE PF13190.6 EON31239.1 - 0.062 13.2 0.3 3.4 7.6 0.0 3.3 3 1 0 3 3 3 0 PDGLE domain Glyco_hydro_16 PF00722.21 EON31240.1 - 3e-25 88.7 0.0 1.6e-24 86.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EON31240.1 - 2.5e-07 29.5 0.1 0.0011 17.4 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Laminin_G_3 PF13385.6 EON31240.1 - 0.12 12.6 1.6 0.46 10.6 0.0 2.4 2 1 1 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Nitroreductase PF00881.24 EON31241.1 - 6e-23 81.7 0.1 1.1e-10 41.9 0.0 2.1 2 0 0 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 EON31241.1 - 0.29 10.7 0.0 24 4.4 0.0 2.3 2 1 0 2 2 2 0 Putative TM nitroreductase MFS_1 PF07690.16 EON31242.1 - 3.1e-50 171.1 56.5 3.5e-50 170.9 55.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON31242.1 - 4.7e-06 25.7 33.3 7e-06 25.2 11.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter FixQ PF05545.11 EON31242.1 - 4.7 7.3 6.8 0.44 10.6 0.4 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TetR_N PF00440.23 EON31243.1 - 3.5e-10 39.5 0.1 5.6e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 EON31243.1 - 0.023 15.4 0.4 0.077 13.7 0.3 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AA_kinase PF00696.28 EON31245.1 - 1.1e-55 188.8 2.1 1.9e-55 188.1 2.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EON31245.1 - 6.7e-18 64.2 0.0 2.2e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EON31245.1 - 2.4e-17 62.4 0.2 5.9e-09 35.6 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 EON31245.1 - 0.00089 19.2 0.1 1.6 8.7 0.0 2.7 2 0 0 2 2 2 2 ACT domain Mak_N_cap PF18085.1 EON31245.1 - 0.017 16.1 0.5 0.21 12.7 0.0 2.8 3 0 0 3 3 3 0 Maltokinase N-terminal cap domain ACT_4 PF13291.6 EON31245.1 - 0.026 15.1 0.0 0.95 10.1 0.0 2.5 2 0 0 2 2 2 0 ACT domain Semialdhyde_dhC PF02774.18 EON31246.1 - 3e-51 174.1 0.0 4.4e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EON31246.1 - 2.5e-30 105.4 0.1 1.4e-29 102.9 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EON31246.1 - 0.033 13.8 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ldh_1_N PF00056.23 EON31246.1 - 0.089 12.9 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FCD PF07729.12 EON31247.1 - 2e-21 76.7 6.4 6.6e-21 75.0 4.7 2.1 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 EON31247.1 - 1.4e-10 40.7 1.1 3.4e-10 39.4 1.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EON31247.1 - 0.00051 20.3 0.1 0.0011 19.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_CodY PF08222.11 EON31247.1 - 0.0089 15.6 1.5 0.019 14.5 1.5 1.5 1 0 0 1 1 1 1 CodY helix-turn-helix domain TrmB PF01978.19 EON31247.1 - 0.027 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EON31247.1 - 0.062 13.4 1.3 0.14 12.3 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 EON31247.1 - 0.18 11.8 0.3 0.36 10.8 0.3 1.5 1 0 0 1 1 1 0 HTH domain SKI PF01202.22 EON31248.1 - 3.4e-14 53.3 0.0 3.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase Cytidylate_kin2 PF13189.6 EON31248.1 - 0.00029 21.0 0.0 0.00039 20.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 EON31248.1 - 0.0049 17.4 0.0 0.0081 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EON31248.1 - 0.0057 16.4 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 EON31248.1 - 0.0071 16.5 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON31248.1 - 0.028 14.8 0.0 0.071 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 EON31248.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 EON31248.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase GntP_permease PF02447.16 EON31249.1 - 7.3e-132 440.2 46.4 8.5e-132 440.0 46.4 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 EON31249.1 - 8e-16 58.1 50.6 8e-16 58.1 50.6 1.9 1 1 1 2 2 2 1 Citrate transporter Reg_prop PF07494.11 EON31250.1 - 0.0096 16.0 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 1 Two component regulator propeller DUF2890 PF11081.8 EON31251.1 - 0.68 10.0 6.2 0.84 9.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) LIP PF03583.14 EON31252.1 - 2e-57 194.7 0.1 2.9e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 EON31252.1 - 9.3e-05 23.1 5.4 9.3e-05 23.1 5.4 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31252.1 - 0.0069 15.7 0.3 0.038 13.2 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON31252.1 - 0.057 12.9 0.4 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EON31252.1 - 0.14 11.8 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4870 PF09685.10 EON31253.1 - 0.046 13.8 0.2 3.8 7.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) Tetraspanin PF00335.20 EON31253.1 - 0.3 10.8 1.3 0.43 10.2 1.3 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4383 PF14325.6 EON31253.1 - 2 8.7 10.4 1.5 9.2 1.1 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4383) Ferritin PF00210.24 EON31254.1 - 1.2e-20 73.9 0.0 1.3e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain TFIIA_gamma_N PF02268.16 EON31254.1 - 0.044 13.8 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF4307 PF14155.6 EON31255.1 - 1.8 8.5 5.8 2.2 8.2 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) DUF2252 PF10009.9 EON31257.1 - 6.4e-132 440.3 1.0 7.4e-132 440.1 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) Toprim_N PF08275.11 EON31257.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain Peptidase_M20 PF01546.28 EON31258.1 - 4.8e-28 98.3 0.1 9.2e-28 97.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON31258.1 - 1.8e-12 47.1 0.0 3.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Acyl-CoA_dh_N PF02771.16 EON31259.1 - 1.3e-11 45.1 0.0 2.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON31259.1 - 0.011 16.0 5.9 0.011 16.0 5.9 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain HTH_18 PF12833.7 EON31260.1 - 4.4e-16 58.9 1.3 1.4e-15 57.3 0.6 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON31260.1 - 8e-13 48.1 0.0 7.1e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 EON31260.1 - 0.002 17.9 0.1 0.0043 16.8 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TetR_N PF00440.23 EON31260.1 - 0.012 15.4 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_22 PF13309.6 EON31260.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_32 PF13565.6 EON31260.1 - 0.043 14.4 0.1 0.087 13.4 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EON31260.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Lipocalin_2 PF08212.12 EON31261.1 - 5.5e-30 104.2 0.0 6.6e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain GerA PF03323.13 EON31262.1 - 0.001 17.6 5.5 0.0016 17.0 5.5 1.2 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Phage_holin_7_1 PF16081.5 EON31262.1 - 0.15 12.3 0.8 0.15 12.3 0.8 2.0 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF373 PF04123.13 EON31262.1 - 0.23 10.9 5.7 0.3 10.5 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3325 PF11804.8 EON31262.1 - 2.5 8.3 11.8 0.66 10.2 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF3040 PF11239.8 EON31262.1 - 7.7 6.9 11.1 3.7 7.9 7.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Hydrolase PF00702.26 EON31264.1 - 3.1e-07 30.9 0.0 5e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EON31264.1 - 2.3e-06 27.8 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON31264.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Metallophos_2 PF12850.7 EON31265.1 - 1.6e-09 38.2 0.0 1.4e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EON31265.1 - 7.2e-08 33.2 0.1 1e-07 32.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transgly PF00912.22 EON31266.1 - 3.7e-55 186.1 0.3 6.4e-55 185.4 0.3 1.4 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 EON31266.1 - 1.7e-19 70.2 0.3 4.7e-19 68.7 0.1 1.8 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PASTA PF03793.19 EON31266.1 - 6.1e-07 29.2 0.1 2.1e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 PASTA domain EGF_MSP1_1 PF12946.7 EON31266.1 - 0.17 11.9 0.3 0.34 11.0 0.3 1.4 1 0 0 1 1 1 0 MSP1 EGF domain 1 Whib PF02467.16 EON31267.1 - 2.9e-16 59.8 1.8 2.9e-16 59.8 1.8 1.8 2 0 0 2 2 2 1 Transcription factor WhiB DUF1289 PF06945.13 EON31267.1 - 0.012 15.4 0.6 1.2 9.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) ArsA_ATPase PF02374.15 EON31268.1 - 7.9e-28 97.5 0.0 3e-27 95.6 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase CbiA PF01656.23 EON31268.1 - 7.8e-11 42.1 0.0 1.7e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EON31268.1 - 8.1e-11 42.1 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 EON31268.1 - 1.2e-06 28.2 1.8 4.8e-05 22.9 1.8 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EON31268.1 - 4.5e-05 23.2 0.2 4.5e-05 23.2 0.2 2.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EON31268.1 - 6.3e-05 22.1 1.1 0.00013 21.0 0.3 1.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EON31268.1 - 0.00012 22.0 0.3 0.00067 19.5 0.1 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EON31268.1 - 0.00013 21.7 0.3 0.00032 20.5 0.3 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EON31268.1 - 0.0005 19.6 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 EON31268.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein MipZ PF09140.11 EON31268.1 - 0.0013 18.1 0.4 0.052 12.8 0.2 2.2 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.6 EON31268.1 - 0.0063 16.4 0.1 0.44 10.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EON31268.1 - 0.0073 15.8 0.1 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EON31268.1 - 0.011 15.3 2.2 0.088 12.4 0.3 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EON31268.1 - 0.012 15.9 0.3 0.029 14.7 0.3 1.9 1 1 0 1 1 1 0 AAA domain Mur_ligase_M PF08245.12 EON31268.1 - 0.018 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Mur ligase middle domain DnaB_C PF03796.15 EON31268.1 - 0.03 13.7 0.2 0.62 9.3 0.1 2.5 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EON31268.1 - 0.041 14.3 0.0 0.041 14.3 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain AAA_33 PF13671.6 EON31268.1 - 0.043 14.0 0.2 0.08 13.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain LpxK PF02606.14 EON31268.1 - 0.055 12.6 0.4 0.091 11.8 0.4 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase YjeF_N PF03853.15 EON31268.1 - 0.086 12.7 0.1 0.086 12.7 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus CLP1_P PF16575.5 EON31268.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 EON31268.1 - 0.12 12.7 3.8 0.38 11.1 3.8 2.0 1 1 0 1 1 1 0 AAA domain Sacchrp_dh_NADP PF03435.18 EON31268.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_4 PF04669.13 EON31268.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis DEAD PF00270.29 EON31268.1 - 0.19 11.5 0.3 0.4 10.4 0.3 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase CobA_CobO_BtuR PF02572.15 EON31268.1 - 0.25 11.6 3.4 0.73 10.1 2.2 2.3 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ArsA_ATPase PF02374.15 EON31269.1 - 2e-21 76.5 0.1 3.9e-17 62.4 0.0 2.1 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 EON31269.1 - 2.7e-12 46.8 0.0 1e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EON31269.1 - 1.7e-09 37.8 0.0 1.2e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 EON31269.1 - 9.1e-07 28.6 1.0 2.1e-06 27.4 0.4 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 EON31269.1 - 5.7e-05 22.8 0.4 0.00013 21.6 0.4 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EON31269.1 - 0.00031 20.3 0.4 0.00092 18.7 0.1 1.9 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EON31269.1 - 0.00032 20.2 0.1 0.00054 19.5 0.1 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 EON31269.1 - 0.00045 19.6 0.9 0.0019 17.5 0.3 2.1 2 0 0 2 2 2 1 ATPase MipZ VirC1 PF07015.11 EON31269.1 - 0.00049 19.5 1.0 0.001 18.4 0.1 1.8 2 0 0 2 2 2 1 VirC1 protein AAA_30 PF13604.6 EON31269.1 - 0.00066 19.4 1.3 0.0016 18.2 1.3 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EON31269.1 - 0.0016 18.1 1.1 0.01 15.5 0.5 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 EON31269.1 - 0.0036 16.5 0.1 0.0063 15.7 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_26 PF13500.6 EON31269.1 - 0.0057 16.5 0.3 0.78 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON31269.1 - 0.0059 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EON31269.1 - 0.0072 15.6 0.1 0.016 14.5 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin PhoH PF02562.16 EON31269.1 - 0.0089 15.5 0.2 0.019 14.4 0.2 1.5 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 EON31269.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 EON31269.1 - 0.024 13.7 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EON31269.1 - 0.04 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 EON31269.1 - 0.045 13.5 0.2 0.082 12.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EON31269.1 - 0.078 12.9 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EON31269.1 - 0.079 12.2 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 EON31269.1 - 0.087 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ResIII PF04851.15 EON31269.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4089 PF13318.6 EON31269.1 - 1.3 9.5 5.2 56 4.3 0.1 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF4089) DUF4177 PF13783.6 EON31270.1 - 2.2e-06 27.8 0.0 3.8e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4177) YjgF_endoribonc PF14588.6 EON31271.1 - 2e-27 96.1 0.1 2.3e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EON31271.1 - 1.2e-22 80.2 0.1 3.1e-22 78.8 0.1 1.6 1 1 0 1 1 1 1 Endoribonuclease L-PSP TauE PF01925.19 EON31272.1 - 4.7e-35 121.3 47.1 5.3e-35 121.2 47.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE TraA PF05513.11 EON31272.1 - 0.07 13.5 9.3 1.6 9.1 0.6 2.8 1 1 1 2 2 2 0 TraA MFS_1 PF07690.16 EON31273.1 - 1e-28 100.3 64.8 7.9e-15 54.6 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EON31273.1 - 1.2e-08 34.0 32.4 5.4e-07 28.5 21.1 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein PP-binding PF00550.25 EON31274.1 - 0.00013 22.3 0.1 0.00016 22.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PhageMin_Tail PF10145.9 EON31274.1 - 0.023 14.6 0.5 0.023 14.6 0.5 1.0 1 0 0 1 1 1 0 Phage-related minor tail protein AMP-binding PF00501.28 EON31275.1 - 3.6e-48 164.2 0.1 1.7e-47 162.0 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON31275.1 - 0.00038 21.4 0.4 0.001 20.0 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EON31275.1 - 0.0034 17.6 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SIP PF04954.13 EON31276.1 - 7.2e-20 71.7 0.1 1.2e-19 71.0 0.1 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 EON31276.1 - 5.8e-11 42.7 0.0 1.6e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain OsmC PF02566.19 EON31277.1 - 1.1e-18 67.5 0.0 1.6e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein MarR PF01047.22 EON31278.1 - 4.9e-14 52.0 0.1 7.2e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON31278.1 - 1.4e-10 40.9 0.2 2.4e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EON31278.1 - 5e-08 33.3 0.1 9.5e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 EON31278.1 - 8.2e-07 29.0 0.2 1.5e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.14 EON31278.1 - 3.8e-06 26.8 0.1 6.3e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EON31278.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 EON31278.1 - 8.7e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 EON31278.1 - 0.00079 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 EON31278.1 - 0.0077 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 EON31278.1 - 0.016 15.0 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Penicillinase_R PF03965.16 EON31278.1 - 0.043 14.2 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Penicillinase repressor Exo_endo_phos PF03372.23 EON31279.1 - 3.7e-21 75.7 2.0 4.7e-21 75.4 2.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acetyltransf_1 PF00583.25 EON31280.1 - 1.8e-05 24.9 0.1 2.7e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EON31280.1 - 0.00014 21.7 0.0 0.00045 20.1 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EON31280.1 - 0.017 15.8 0.0 0.027 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pep_deformylase PF01327.21 EON31281.1 - 3e-39 134.2 0.0 3.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Palm_thioest PF02089.15 EON31282.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF3263 PF11662.8 EON31283.1 - 5.5e-38 128.7 2.5 7.1e-38 128.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3263) LytR_C PF13399.6 EON31284.1 - 5.1e-11 43.4 1.8 8.2e-11 42.7 0.2 1.8 1 1 1 2 2 2 1 LytR cell envelope-related transcriptional attenuator Sod_Cu PF00080.20 EON31285.1 - 1.1e-32 113.2 4.9 1.4e-32 112.8 4.9 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) GCS2 PF04107.13 EON31286.1 - 1.3e-77 261.0 0.0 1.6e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) DUF1304 PF06993.12 EON31287.1 - 8.1e-31 106.3 9.6 8.1e-31 106.3 9.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1304) PIG-Y PF15159.6 EON31287.1 - 0.03 15.2 1.9 0.053 14.5 0.3 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SDH_alpha PF03313.15 EON31287.1 - 0.051 13.3 6.1 0.052 13.2 6.1 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain DUF2791 PF10923.8 EON31287.1 - 0.13 11.1 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PhaG_MnhG_YufB PF03334.14 EON31288.1 - 4.8e-27 94.0 8.2 5.6e-27 93.8 8.2 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit DUF1634 PF07843.11 EON31288.1 - 0.21 11.7 2.8 0.5 10.5 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) TPPK_C PF12555.8 EON31288.1 - 0.31 11.1 0.4 0.31 11.1 0.4 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal MrpF_PhaF PF04066.13 EON31289.1 - 9.2e-15 54.8 6.3 9.2e-15 54.8 6.3 1.9 2 0 0 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) E1-E2_ATPase PF00122.20 EON31289.1 - 6.7 6.2 7.1 0.84 9.1 2.6 1.6 1 1 1 2 2 2 0 E1-E2 ATPase MHYT PF03707.16 EON31289.1 - 8.5 6.6 15.6 0.084 13.0 1.5 2.9 1 1 2 3 3 3 0 Bacterial signalling protein N terminal repeat MNHE PF01899.16 EON31290.1 - 3.4e-30 104.7 6.1 3.4e-30 104.7 6.1 1.5 2 0 0 2 2 2 1 Na+/H+ ion antiporter subunit Proton_antipo_M PF00361.20 EON31291.1 - 4.7e-62 209.8 21.1 4.7e-62 209.8 21.1 2.4 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 EON31291.1 - 8e-05 22.6 0.5 8e-05 22.6 0.5 3.8 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADHdeh_related PF10125.9 EON31291.1 - 0.0012 18.3 5.3 0.0012 18.3 5.3 3.3 4 0 0 4 4 4 1 NADH dehydrogenase I, subunit N related protein GET2 PF08690.10 EON31291.1 - 0.032 13.9 0.3 0.049 13.3 0.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Tmemb_170 PF10190.9 EON31291.1 - 0.081 13.3 0.6 0.081 13.3 0.6 4.5 3 2 1 4 4 4 0 Putative transmembrane protein 170 Oxidored_q2 PF00420.24 EON31292.1 - 2.9e-20 71.8 1.5 4.1e-20 71.4 1.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Trp_oprn_chp PF09534.10 EON31292.1 - 0.22 11.3 1.0 0.37 10.6 1.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Proton_antipo_M PF00361.20 EON31293.1 - 3.3e-59 200.5 22.5 1.1e-58 198.7 22.5 1.9 1 0 0 1 1 1 1 Proton-conducting membrane transporter MnhB PF04039.13 EON31293.1 - 5.6e-29 101.0 14.2 5.6e-29 101.0 14.2 7.4 3 2 1 6 6 6 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 EON31293.1 - 2.8e-21 75.4 9.2 2.8e-21 75.4 9.2 6.2 6 0 0 6 6 6 1 Domain of unknown function (DUF4040) Proton_antipo_N PF00662.20 EON31293.1 - 4.4e-05 23.5 3.1 4.5e-05 23.4 0.1 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Aldedh PF00171.22 EON31295.1 - 1.1e-148 495.6 0.9 1.3e-148 495.4 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EON31295.1 - 0.19 11.2 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) adh_short PF00106.25 EON31296.1 - 4.9e-49 166.5 1.3 6.3e-49 166.1 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31296.1 - 3.8e-48 164.1 3.4 3.5e-47 160.9 3.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31296.1 - 7.5e-08 32.5 3.0 1.8e-07 31.3 3.0 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EON31296.1 - 0.016 15.1 0.5 0.026 14.4 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 EON31296.1 - 0.23 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fer4_13 PF13370.6 EON31297.1 - 5.4e-08 33.3 0.2 6.3e-08 33.0 0.2 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EON31297.1 - 2.3e-07 31.4 1.0 2.9e-07 31.1 1.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain p450 PF00067.22 EON31298.1 - 2.3e-26 92.6 0.0 2.4e-21 76.0 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 Ring_hydroxyl_A PF00848.19 EON31299.1 - 6.4e-21 75.3 0.2 1.4e-20 74.2 0.2 1.5 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EON31299.1 - 6.8e-16 58.0 0.0 1.6e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain HicA_toxin PF07927.12 EON31299.1 - 0.18 11.8 0.5 37 4.5 0.0 2.9 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, AMP-binding PF00501.28 EON31300.1 - 2e-95 319.9 0.0 2.8e-95 319.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON31300.1 - 3e-12 47.3 0.5 7.4e-12 46.1 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TetR_N PF00440.23 EON31301.1 - 1.1e-16 60.3 0.0 1.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 EON31301.1 - 0.00023 21.2 0.1 0.00056 19.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase TetR_C_11 PF16859.5 EON31301.1 - 0.00061 20.1 0.8 0.0016 18.7 0.1 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 EON31301.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain LacI PF00356.21 EON31301.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_Tnp_1_2 PF13022.6 EON31301.1 - 0.0082 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_22 PF13309.6 EON31301.1 - 0.019 15.0 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_3 PF01381.22 EON31301.1 - 0.023 14.8 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix Phage_NinH PF06322.11 EON31301.1 - 0.047 13.6 0.0 0.78 9.7 0.0 2.5 2 1 1 3 3 3 0 Phage NinH protein HTH_AsnC-type PF13404.6 EON31301.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EON31301.1 - 0.059 13.9 0.1 0.17 12.4 0.1 1.8 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 TrmB PF01978.19 EON31301.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TetR_C_29 PF17938.1 EON31301.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_ISL3 PF13542.6 EON31301.1 - 0.077 12.4 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Acyl-CoA_dh_1 PF00441.24 EON31302.1 - 3.5e-40 137.7 0.7 5e-40 137.1 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON31302.1 - 1.6e-27 95.6 0.0 2.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON31302.1 - 5.6e-27 94.6 0.0 1.4e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON31302.1 - 7.7e-11 42.4 0.1 1.4e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short_C2 PF13561.6 EON31303.1 - 1.6e-61 207.8 0.1 1.9e-61 207.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31303.1 - 8.7e-54 181.9 0.0 1e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31303.1 - 1.6e-12 47.7 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31303.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EON31303.1 - 0.0066 15.6 0.0 0.0095 15.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 EON31303.1 - 0.0071 16.2 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON31303.1 - 0.029 15.0 0.0 0.063 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_trans_4_4 PF13579.6 EON31303.1 - 0.074 13.5 2.7 0.16 12.4 2.7 1.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain ApbA PF02558.16 EON31303.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ECH_1 PF00378.20 EON31304.1 - 1.4e-59 201.5 0.1 1.6e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31304.1 - 3.9e-35 121.9 0.1 4.8e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 EON31304.1 - 0.00091 18.3 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Peptidase_S49 PF01343.18 EON31304.1 - 0.088 12.8 0.0 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 ECH_1 PF00378.20 EON31305.1 - 3.2e-58 197.0 0.0 3.9e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31305.1 - 9.9e-30 104.2 0.0 8.9e-28 97.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EcKinase PF02958.20 EON31306.1 - 3.8e-13 49.4 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 EON31306.1 - 6.8e-08 31.8 0.0 1.6e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) APH PF01636.23 EON31306.1 - 0.00027 21.0 10.0 0.00038 20.5 9.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family adh_short_C2 PF13561.6 EON31307.1 - 6.3e-62 209.2 10.7 7.4e-62 209.0 10.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31307.1 - 9.1e-59 198.2 7.5 1.2e-58 197.8 7.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31307.1 - 2e-11 44.1 4.5 4.5e-11 43.0 4.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31307.1 - 0.00047 19.7 4.5 0.00049 19.6 2.7 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EON31307.1 - 0.0021 18.0 3.3 0.0034 17.3 3.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EON31307.1 - 0.0029 16.7 0.9 0.0042 16.1 0.9 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CbiA PF01656.23 EON31307.1 - 0.0054 16.8 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DapB_N PF01113.20 EON31307.1 - 0.012 15.7 1.4 0.025 14.7 1.4 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 EON31307.1 - 0.014 14.5 0.2 0.023 13.8 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EON31307.1 - 0.015 14.6 0.5 0.031 13.7 0.5 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EON31307.1 - 0.066 12.3 0.1 0.083 12.0 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 EON31307.1 - 0.069 13.2 2.3 0.11 12.6 2.3 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 EON31307.1 - 0.16 11.5 2.3 0.61 9.6 2.4 1.9 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.17 EON31307.1 - 0.45 11.1 4.8 0.27 11.8 2.5 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N_2 PF13602.6 EON31308.1 - 1.1e-08 36.3 0.2 2.2e-08 35.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EON31308.1 - 3.9e-08 33.3 0.1 9.4e-08 32.1 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON31308.1 - 5.8e-07 29.4 0.0 9.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EON31308.1 - 0.1 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TetR_N PF00440.23 EON31309.1 - 8e-20 70.4 0.5 3.6e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON31309.1 - 0.00015 21.9 3.5 0.00015 21.9 3.5 3.3 3 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain F-box_5 PF18511.1 EON31309.1 - 0.012 15.1 0.4 0.037 13.6 0.4 1.8 1 0 0 1 1 1 0 F-box HTH_Tnp_1_2 PF13022.6 EON31309.1 - 0.14 12.4 0.0 0.95 9.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_AraC PF00165.23 EON31309.1 - 0.18 11.9 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family adh_short_C2 PF13561.6 EON31310.1 - 4.1e-58 196.7 0.2 5e-58 196.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31310.1 - 8.7e-51 172.2 0.1 1.1e-50 171.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31310.1 - 2.1e-12 47.3 0.3 3.1e-12 46.8 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31310.1 - 0.00075 19.0 0.2 0.0036 16.8 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EON31310.1 - 0.0045 16.4 0.0 0.0065 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF2236 PF09995.9 EON31311.1 - 9.8e-22 78.3 0.9 1.6e-21 77.5 0.9 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Fer4_13 PF13370.6 EON31312.1 - 4.2e-09 36.8 0.0 4.6e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EON31312.1 - 7.5e-08 33.0 0.7 1.9e-07 31.7 0.7 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 EON31312.1 - 0.00021 21.3 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster AMP-binding PF00501.28 EON31314.1 - 1e-86 291.2 0.0 1.3e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_8 PF13450.6 EON31315.1 - 2.4e-16 59.7 0.2 1e-12 48.0 0.0 3.9 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON31315.1 - 6.7e-16 58.4 0.0 2e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON31315.1 - 9.2e-16 57.3 0.0 2.8e-15 55.7 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON31315.1 - 7.7e-15 54.9 0.2 3.2e-13 49.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON31315.1 - 1.4e-12 47.4 0.3 1.7e-07 30.8 0.0 3.5 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON31315.1 - 1.2e-09 38.2 7.2 9.9e-06 25.4 0.3 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON31315.1 - 1.1e-05 24.9 0.1 0.00015 21.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON31315.1 - 1.5e-05 23.9 3.5 0.0076 15.0 0.4 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 EON31315.1 - 1.5e-05 25.4 0.1 0.17 12.4 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON31315.1 - 1.8e-05 24.0 0.0 0.0001 21.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EON31315.1 - 3.9e-05 23.7 4.2 0.01 15.8 0.1 4.0 4 1 0 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.22 EON31315.1 - 0.00024 20.3 0.5 0.22 10.5 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EON31315.1 - 0.00079 19.8 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EON31315.1 - 0.0028 16.7 1.6 0.0055 15.8 0.2 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EON31315.1 - 0.0053 16.1 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EON31315.1 - 0.0056 16.1 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON31315.1 - 0.0063 15.9 0.9 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EON31315.1 - 0.036 14.0 0.9 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EON31315.1 - 0.036 13.7 0.2 0.064 12.9 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EON31315.1 - 0.042 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 EON31315.1 - 0.063 13.8 0.0 19 5.8 0.0 3.0 2 1 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 EON31315.1 - 0.074 12.6 0.2 0.17 11.4 0.2 1.6 2 0 0 2 2 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 EON31315.1 - 0.13 11.8 0.1 1.8 8.1 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 EON31315.1 - 0.13 11.5 0.1 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EON31315.1 - 0.14 11.4 0.3 5.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EON31315.1 - 0.2 11.7 0.0 6.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Acyl-CoA_dh_1 PF00441.24 EON31316.1 - 6.7e-40 136.7 2.3 9.5e-40 136.2 2.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31316.1 - 2.2e-29 102.4 0.1 9.3e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31316.1 - 3.6e-28 97.6 0.0 6.4e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31316.1 - 5.5e-10 39.6 5.7 9.2e-10 38.9 5.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EON31317.1 - 5.8e-44 149.9 6.1 8.4e-44 149.4 6.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31317.1 - 1.8e-28 99.4 0.2 9.2e-28 97.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31317.1 - 6.3e-23 80.8 0.0 1.9e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31317.1 - 1.1e-15 58.1 4.6 1.9e-15 57.3 4.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoA_transf_3 PF02515.17 EON31318.1 - 2.7e-77 260.4 0.0 3.4e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF2236 PF09995.9 EON31319.1 - 3.9e-25 89.4 0.1 4.8e-24 85.8 0.0 2.3 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2236) Nitroreductase PF00881.24 EON31320.1 - 1.4e-33 116.3 0.0 1.7e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EON31320.1 - 3.1e-07 30.2 0.0 0.0059 16.2 0.0 2.7 2 1 1 3 3 3 2 Putative TM nitroreductase TPR_20 PF14561.6 EON31320.1 - 0.041 14.2 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EON31321.1 - 1.5e-24 87.1 0.1 1.7e-23 83.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31321.1 - 2.2e-24 87.3 11.9 2.5e-24 87.1 11.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31321.1 - 7.5e-18 64.7 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EON31321.1 - 1.9e-06 28.2 0.0 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EON31321.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 EON31321.1 - 0.037 13.6 0.1 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 EON31321.1 - 0.045 12.5 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF5010 PF16402.5 EON31321.1 - 0.077 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) DUF2048 PF09752.9 EON31321.1 - 0.26 10.3 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 AXE1 PF05448.12 EON31321.1 - 0.3 9.7 0.1 1 7.9 0.0 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) TetR_N PF00440.23 EON31322.1 - 1.3e-17 63.3 1.5 6.5e-08 32.3 0.1 2.8 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EON31322.1 - 0.00011 22.5 16.9 0.00011 22.5 1.5 4.0 3 1 1 4 4 4 2 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 EON31322.1 - 0.006 16.6 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase RFamide_26RFa PF11109.8 EON31322.1 - 0.026 15.0 0.1 0.088 13.3 0.0 2.0 1 1 1 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 HTH_AraC PF00165.23 EON31322.1 - 0.05 13.7 1.8 0.29 11.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family ECH_1 PF00378.20 EON31323.1 - 4.9e-51 173.5 0.0 6.1e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31323.1 - 2.1e-24 86.7 0.1 2.5e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Eno-Rase_NADH_b PF12242.8 EON31323.1 - 0.12 12.1 2.3 1.1 9.1 0.1 2.5 1 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldedh PF00171.22 EON31324.1 - 1.7e-79 267.5 0.0 2.1e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON31324.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) MlaE PF02405.16 EON31325.1 - 1.5e-55 188.2 19.7 1.9e-55 187.9 19.7 1.1 1 0 0 1 1 1 1 Permease MlaE FtsX PF02687.21 EON31325.1 - 4.4 7.9 14.9 0.062 13.8 3.6 2.6 3 0 0 3 3 3 0 FtsX-like permease family MlaE PF02405.16 EON31326.1 - 2e-51 174.7 22.8 2.8e-51 174.2 22.8 1.2 1 0 0 1 1 1 1 Permease MlaE MlaD PF02470.20 EON31327.1 - 7.5e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON31328.1 - 2.2e-14 53.5 0.1 4.2e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON31329.1 - 6.3e-10 39.2 1.4 9.8e-10 38.6 0.4 1.9 2 0 0 2 2 2 1 MlaD protein TOBE_2 PF08402.10 EON31329.1 - 0.0039 17.3 1.1 2.6 8.3 0.2 2.5 2 0 0 2 2 2 2 TOBE domain AlaDh_PNT_C PF01262.21 EON31329.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EzrA PF06160.12 EON31329.1 - 0.14 10.4 0.0 0.23 9.6 0.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MlaD PF02470.20 EON31330.1 - 1.6e-08 34.7 0.0 2.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON31331.1 - 1.1e-14 54.4 0.1 2.1e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 MlaD protein DASH_Dad1 PF08649.10 EON31331.1 - 0.0079 16.4 0.0 0.26 11.5 0.0 2.4 1 1 1 2 2 2 1 DASH complex subunit Dad1 HsbA PF12296.8 EON31331.1 - 0.07 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A MlaD PF02470.20 EON31332.1 - 2.9e-10 40.3 0.5 7.2e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 MlaD protein Peptidase_M78 PF06114.13 EON31335.1 - 0.00023 21.1 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 IrrE N-terminal-like domain DUF2268 PF10026.9 EON31335.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Meth_synt_2 PF01717.18 EON31338.1 - 3.6e-36 125.1 0.0 7e-36 124.1 0.0 1.4 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain CNP1 PF08750.11 EON31338.1 - 0.0056 16.6 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 CNP1-like family Meth_synt_1 PF08267.12 EON31338.1 - 0.0076 15.8 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain DUF1852 PF08908.11 EON31339.1 - 9.8e-155 514.4 0.0 1.1e-154 514.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1852) CCP_MauG PF03150.14 EON31339.1 - 0.18 12.5 0.0 0.39 11.3 0.0 1.5 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase HTH_1 PF00126.27 EON31340.1 - 1.6e-20 72.8 0.2 8.2e-20 70.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EON31340.1 - 4e-08 32.9 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 EON31340.1 - 0.0034 17.1 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain DUF1932 PF09130.11 EON31340.1 - 0.076 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) His_Phos_1 PF00300.22 EON31341.1 - 5.8e-38 130.5 1.1 6.5e-38 130.4 1.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PDT PF00800.18 EON31342.1 - 1.3e-34 119.6 0.0 2.2e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EON31342.1 - 1.6e-07 31.0 0.0 4.5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 ACT domain CW_binding_2 PF04122.12 EON31342.1 - 0.073 13.7 3.1 0.43 11.3 0.7 2.6 3 0 0 3 3 3 0 Putative cell wall binding repeat 2 DUF4699 PF15770.5 EON31342.1 - 0.13 12.1 0.5 0.25 11.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) PBP_like PF12727.7 EON31342.1 - 0.27 10.3 3.7 1.2 8.3 1.4 2.2 2 0 0 2 2 2 0 PBP superfamily domain Phosphonate-bd PF12974.7 EON31342.1 - 0.33 10.5 4.4 4.6 6.8 1.1 2.2 1 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF2470 PF10615.9 EON31343.1 - 6.3e-07 29.9 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) CPBP PF02517.16 EON31344.1 - 5.2e-11 42.8 3.4 5.2e-11 42.8 3.4 2.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease STALD PF18185.1 EON31344.1 - 0.19 11.0 0.2 0.3 10.4 0.2 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family DUF2236 PF09995.9 EON31345.1 - 3.9e-24 86.1 15.5 3.9e-24 86.1 15.5 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) GMC_oxred_N PF00732.19 EON31345.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase CSD PF00313.22 EON31346.1 - 1e-07 31.7 0.0 1.6e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 'Cold-shock' DNA-binding domain AA_permease_2 PF13520.6 EON31347.1 - 5.8e-50 170.4 23.9 7.9e-50 169.9 23.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON31347.1 - 5.4e-35 120.9 23.9 7.3e-35 120.5 23.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EON31347.1 - 2.3e-05 24.4 0.8 2.3e-05 24.4 0.8 3.4 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 EON31347.1 - 4.9e-05 22.3 10.3 9.9e-05 21.3 2.1 2.4 2 1 0 2 2 2 2 Spore germination protein DUF3397 PF11877.8 EON31347.1 - 0.049 13.8 2.6 0.17 12.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) LytR_cpsA_psr PF03816.14 EON31348.1 - 4.3e-41 140.6 0.0 5.7e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Ferritin PF00210.24 EON31349.1 - 3.2e-32 111.4 0.9 3.9e-32 111.1 0.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 EON31349.1 - 4.2e-06 27.2 0.1 6.2e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Rubrerythrin ARTD15_N PF18084.1 EON31350.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 ARTD15 N-terminal domain GDPD PF03009.17 EON31351.1 - 1.6e-42 146.0 0.0 1.9e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4328 PF14219.6 EON31352.1 - 1.5e-16 60.4 21.2 1.5e-16 60.4 21.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) DUF973 PF06157.11 EON31352.1 - 0.028 13.5 0.1 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) SUR7 PF06687.12 EON31352.1 - 0.29 10.7 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 SUR7/PalI family COX4 PF02936.14 EON31352.1 - 0.31 11.1 0.6 0.97 9.4 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Rhodanese PF00581.20 EON31353.1 - 3.6e-15 56.4 0.0 4.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S49 PF01343.18 EON31354.1 - 1e-28 100.2 0.0 1.7e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 EON31354.1 - 0.00013 21.1 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 EON31354.1 - 0.019 14.8 0.2 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Clp protease Glyoxalase_6 PF18029.1 EON31355.1 - 6.4e-34 117.0 2.4 1.9e-16 60.8 0.2 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain HTH_42 PF06224.12 EON31356.1 - 1.2e-66 225.6 14.4 1.4e-66 225.3 14.4 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain PMSR PF01625.21 EON31357.1 - 2.3e-61 206.4 0.1 2.7e-61 206.2 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sod_Fe_C PF02777.18 EON31359.1 - 3.9e-35 120.1 0.1 5.8e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EON31359.1 - 1.1e-29 102.7 0.4 1.1e-29 102.7 0.4 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CbiQ PF02361.16 EON31360.1 - 4.7e-23 81.9 19.5 4.7e-23 81.9 19.5 2.3 2 1 0 2 2 2 1 Cobalt transport protein ABC_tran PF00005.27 EON31361.1 - 6e-46 156.4 0.0 1.8e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON31361.1 - 5.5e-15 56.0 4.3 0.00037 20.4 0.0 4.1 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON31361.1 - 4.4e-10 39.4 1.5 0.094 12.1 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON31361.1 - 5.3e-08 32.5 0.6 0.0066 16.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF2232 PF09991.9 EON31361.1 - 2.3e-07 30.3 3.2 3.7e-07 29.6 3.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) AAA_23 PF13476.6 EON31361.1 - 4.8e-06 27.2 0.8 0.076 13.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EON31361.1 - 7.5e-05 22.6 0.1 0.078 12.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EON31361.1 - 0.0002 21.6 3.8 0.055 13.7 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EON31361.1 - 0.00033 20.9 3.5 0.53 10.4 0.3 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EON31361.1 - 0.00052 19.6 4.9 0.0082 15.7 0.7 3.4 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EON31361.1 - 0.00054 18.7 0.9 0.33 9.5 0.2 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EON31361.1 - 0.0011 19.4 3.3 0.83 10.0 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 EON31361.1 - 0.0012 18.2 0.6 0.063 12.7 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 EON31361.1 - 0.0016 18.7 0.4 1.8 8.8 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EON31361.1 - 0.0024 18.3 0.1 1.7 9.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EON31361.1 - 0.0026 18.0 2.9 0.45 10.7 0.3 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EON31361.1 - 0.0034 17.3 3.9 0.48 10.3 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 EON31361.1 - 0.0079 15.9 2.8 1.8 8.2 0.1 2.7 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 EON31361.1 - 0.0088 15.4 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 EON31361.1 - 0.009 15.8 2.5 6.8 6.4 0.4 3.9 4 1 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 EON31361.1 - 0.0095 15.1 1.1 0.35 10.0 0.1 2.5 3 0 0 3 3 3 1 NB-ARC domain ATPase PF06745.13 EON31361.1 - 0.0097 15.3 0.5 9 5.6 0.1 3.4 3 0 0 3 3 3 0 KaiC RuvB_N PF05496.12 EON31361.1 - 0.038 13.8 1.5 6.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EON31361.1 - 0.061 12.6 1.6 4.6 6.5 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 EON31361.1 - 0.066 12.3 0.7 1 8.4 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EON31361.1 - 0.07 13.5 0.7 6.2 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 EON31361.1 - 0.091 12.8 1.0 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EON31361.1 - 0.1 12.5 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 EON31361.1 - 0.11 12.5 1.9 8.1 6.4 0.2 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 EON31361.1 - 0.18 9.3 0.2 4.1 4.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_18 PF13238.6 EON31361.1 - 0.19 12.3 3.2 1.4 9.5 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EON31361.1 - 0.23 11.8 2.5 14 6.0 0.3 3.3 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EON31361.1 - 0.27 10.8 2.0 7.9 6.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EON31361.1 - 0.62 10.2 2.6 0.69 10.0 0.2 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0016 PF01169.19 EON31363.1 - 1.3e-41 140.7 32.5 8.6e-21 74.1 8.2 3.2 3 0 0 3 3 3 3 Uncharacterized protein family UPF0016 FtsL PF04999.13 EON31363.1 - 0.034 14.1 4.2 0.2 11.7 0.1 2.5 2 0 0 2 2 2 0 Cell division protein FtsL Nitrate_red_gam PF02665.14 EON31363.1 - 0.63 9.5 18.4 2.2 7.8 2.3 3.5 1 1 2 3 3 3 0 Nitrate reductase gamma subunit TauE PF01925.19 EON31363.1 - 1.8 8.1 29.9 1.5e+02 1.9 30.0 2.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF4131 PF13567.6 EON31363.1 - 2.2 7.9 18.2 0.35 10.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) adh_short PF00106.25 EON31364.1 - 1.5e-41 142.0 3.5 2e-41 141.6 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31364.1 - 2.6e-41 141.7 3.3 3.3e-41 141.4 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31364.1 - 4.1e-08 33.4 8.2 8.8e-07 29.0 8.2 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31364.1 - 6.1e-06 25.9 0.5 1.3e-05 24.7 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FtsJ PF01728.19 EON31364.1 - 0.0097 16.0 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RmlD_sub_bind PF04321.17 EON31364.1 - 0.07 12.2 0.3 0.13 11.4 0.3 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EON31364.1 - 0.63 9.5 5.1 0.16 11.5 1.9 1.6 2 0 0 2 2 2 0 NmrA-like family GBR2_CC PF18455.1 EON31366.1 - 0.029 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain HTH_3 PF01381.22 EON31367.1 - 0.0013 18.7 0.0 0.0084 16.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 EON31367.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 EON31367.1 - 0.012 16.0 0.2 0.063 13.6 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4158 PF13700.6 EON31367.1 - 0.014 15.3 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) HTH_19 PF12844.7 EON31367.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain GTPase_binding PF09027.10 EON31367.1 - 0.038 14.0 0.1 0.092 12.7 0.1 1.6 1 0 0 1 1 1 0 GTPase binding RNase_H_2 PF13482.6 EON31369.1 - 2.1e-11 44.1 0.0 2.9e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 RNase_H superfamily Cas6 PF09559.10 EON31370.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Cas6 Crispr DUF4614 PF15391.6 EON31370.1 - 0.18 11.8 7.5 0.039 14.0 3.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) HC2 PF07382.11 EON31371.1 - 0.05 13.7 36.9 0.1 12.7 36.9 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Abhydrolase_1 PF00561.20 EON31372.1 - 3.8e-25 89.0 0.1 2.6e-22 79.7 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31372.1 - 1.3e-20 74.9 18.6 1.6e-20 74.6 18.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31372.1 - 1.2e-07 31.3 0.0 2.2e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cyclase PF04199.13 EON31373.1 - 1.9e-30 105.8 0.1 2.6e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase GSDH PF07995.11 EON31374.1 - 5.5e-70 236.3 0.0 6.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EON31374.1 - 0.0076 16.2 0.2 0.66 10.1 0.0 2.9 2 0 0 2 2 2 1 NHL repeat WD40 PF00400.32 EON31374.1 - 0.032 15.1 0.0 0.81 10.7 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat SUKH-4 PF14435.6 EON31374.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 SUKH-4 immunity protein Aldedh PF00171.22 EON31375.1 - 1.5e-137 458.9 2.9 1.7e-137 458.7 2.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON31375.1 - 1.4e-06 27.6 0.0 2.5e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RraA-like PF03737.15 EON31376.1 - 4.4e-41 140.5 2.2 5e-41 140.4 2.2 1.0 1 0 0 1 1 1 1 Aldolase/RraA Abhydrolase_6 PF12697.7 EON31377.1 - 1.5e-15 58.4 14.7 1.8e-15 58.2 14.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON31377.1 - 4.4e-08 33.1 0.1 6.2e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON31377.1 - 8.4e-07 28.5 0.0 1.2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 NrfD_2 PF14589.6 EON31377.1 - 0.038 14.0 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Polysulfide reductase Sigma70_r2 PF04542.14 EON31378.1 - 1.3e-15 57.0 1.5 1.3e-15 57.0 1.5 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON31378.1 - 6e-10 38.7 0.0 9.8e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON31378.1 - 1.4e-08 34.2 0.1 4.7e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 DUF2156 PF09924.9 EON31379.1 - 2.7e-92 309.0 0.0 3.8e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2_TM PF16995.5 EON31379.1 - 5.3e-76 255.1 17.7 7.6e-76 254.6 17.7 1.2 1 0 0 1 1 1 1 Transmembrane region of lysyl-tRNA synthetase tRNA-synt_2 PF00152.20 EON31379.1 - 4.6e-67 226.3 0.0 6.4e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EON31379.1 - 2.1e-12 46.8 0.6 5.3e-12 45.6 0.6 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EON31379.1 - 8.5e-05 22.1 0.0 0.0037 16.8 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) 7TM_GPCR_Srz PF10325.9 EON31379.1 - 0.23 10.8 0.4 0.35 10.1 0.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz MASE3 PF17159.4 EON31379.1 - 0.24 11.0 7.1 0.46 10.1 7.1 1.4 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF2070 PF09843.9 EON31379.1 - 6.7 4.9 7.9 12 4.1 7.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF983 PF06170.12 EON31379.1 - 9.2 6.8 8.0 29 5.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) S4_2 PF13275.6 EON31380.1 - 7.7e-28 96.1 0.6 8.7e-28 95.9 0.6 1.0 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 EON31380.1 - 9.6e-06 25.2 0.2 1.3e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 S4 domain Polyketide_cyc2 PF10604.9 EON31381.1 - 3.6e-12 46.8 0.2 3.9e-12 46.6 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON31381.1 - 0.093 12.9 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport SNARE_assoc PF09335.11 EON31382.1 - 1e-24 87.3 5.2 3.7e-24 85.5 3.9 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein TM_helix PF05552.12 EON31382.1 - 0.00097 19.1 0.3 0.00097 19.1 0.3 2.9 3 0 0 3 3 3 1 Conserved TM helix DUF1129 PF06570.11 EON31382.1 - 0.0073 15.8 2.1 0.0073 15.8 2.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) FeoB_associated PF12669.7 EON31382.1 - 0.034 14.5 0.6 0.07 13.5 0.6 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1614 PF07758.11 EON31382.1 - 0.085 12.9 1.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) Phage_holin_2_4 PF16082.5 EON31382.1 - 3.3 7.5 7.8 4.4 7.1 0.2 2.9 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Cutinase PF01083.22 EON31383.1 - 6.4e-15 55.6 0.0 9.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EON31383.1 - 0.00041 20.0 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EON31383.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LIP PF03583.14 EON31383.1 - 0.19 11.0 0.2 0.28 10.5 0.2 1.2 1 0 0 1 1 1 0 Secretory lipase Pyr_redox_2 PF07992.14 EON31384.1 - 5.5e-26 91.5 1.1 1.5e-25 90.1 1.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EON31384.1 - 1.3e-22 79.6 0.0 2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EON31384.1 - 1e-10 41.7 1.4 1.4e-10 41.2 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON31384.1 - 4.7e-09 36.0 2.8 1.5e-08 34.4 0.3 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EON31384.1 - 1.1e-08 35.5 0.1 1.3e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON31384.1 - 1.5e-07 31.2 0.1 2.7e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON31384.1 - 3.5e-07 29.8 0.0 0.021 14.1 0.0 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON31384.1 - 8.1e-07 28.5 1.0 4.6e-05 22.7 0.7 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON31384.1 - 3e-06 26.2 0.9 1.3e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EON31384.1 - 1.4e-05 24.5 2.1 2.8e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 EON31384.1 - 1.5e-05 23.6 0.0 0.0027 16.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 EON31384.1 - 1.9e-05 25.0 0.2 0.17 12.3 0.1 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.24 EON31384.1 - 4.3e-05 23.3 0.4 4.3e-05 23.3 0.4 3.0 2 1 1 4 4 4 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EON31384.1 - 6.2e-05 22.4 0.3 0.11 11.8 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EON31384.1 - 0.00019 20.6 2.4 0.00061 19.0 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EON31384.1 - 0.0017 17.7 1.6 0.0029 16.9 0.1 2.1 3 0 0 3 3 3 1 Thi4 family ApbA PF02558.16 EON31384.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EON31384.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EON31384.1 - 0.017 14.3 0.2 5.1 6.1 0.0 2.8 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 EON31384.1 - 0.018 15.6 0.1 5.6 7.6 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 EON31384.1 - 0.022 13.8 0.3 0.039 13.0 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EON31384.1 - 0.026 14.5 5.1 0.048 13.6 0.1 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding YjeF_N PF03853.15 EON31384.1 - 0.057 13.3 0.1 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.23 EON31384.1 - 0.08 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 EON31384.1 - 0.084 12.9 2.3 6.4 6.8 0.4 2.4 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EON31384.1 - 0.13 11.7 0.2 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EON31384.1 - 0.14 11.8 1.3 0.38 10.3 0.1 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fer4_4 PF12800.7 EON31384.1 - 3.5 8.4 7.8 0.43 11.2 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Trp_halogenase PF04820.14 EON31384.1 - 7.4 5.3 6.9 0.25 10.1 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase GATase_2 PF00310.21 EON31385.1 - 5e-179 595.4 0.0 6.4e-179 595.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EON31385.1 - 5.6e-151 502.8 0.0 3e-150 500.5 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EON31385.1 - 8e-114 379.8 0.0 1.3e-113 379.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 EON31385.1 - 5.3e-80 267.5 4.6 9.4e-80 266.7 4.6 1.4 1 0 0 1 1 1 1 GXGXG motif Abhydrolase_3 PF07859.13 EON31386.1 - 1.9e-41 142.2 0.0 2.7e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON31386.1 - 0.00066 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EON31386.1 - 0.028 13.7 0.0 0.093 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON31386.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family RPE65 PF03055.15 EON31387.1 - 3.2e-94 316.7 0.0 3.6e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2254 PF10011.9 EON31388.1 - 2.1e-68 230.8 2.5 2.1e-68 230.8 2.5 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2254) Mannosyl_trans2 PF04188.13 EON31388.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) GGDEF PF00990.21 EON31389.1 - 1.2e-10 41.4 0.0 2.1e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain 7TMR-DISM_7TM PF07695.11 EON31389.1 - 0.87 9.4 9.7 1.3 8.9 4.9 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Response_reg PF00072.24 EON31390.1 - 2.4e-22 79.2 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON31390.1 - 1.2e-14 53.6 0.0 1.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON31390.1 - 0.00041 20.0 0.0 0.00087 18.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON31390.1 - 0.0084 15.6 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_30 PF13556.6 EON31390.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 EON31390.1 - 0.11 12.4 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HATPase_c PF02518.26 EON31391.1 - 1.6e-05 25.4 0.0 2.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 EON31391.1 - 9.5e-05 22.8 3.9 0.00036 21.0 3.9 2.0 1 0 0 1 1 1 1 Histidine kinase HATPase_c_3 PF13589.6 EON31391.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EON31391.1 - 0.066 13.2 0.1 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain BatA PF07584.11 EON31391.1 - 0.42 11.0 7.1 0.11 12.8 1.0 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Caps_synth_CapC PF14102.6 EON31391.1 - 2.6 8.5 11.6 0.31 11.5 6.5 2.0 1 1 0 1 1 1 0 Capsule biosynthesis CapC Beta-lactamase PF00144.24 EON31392.1 - 2.2e-63 214.5 4.1 2.9e-63 214.1 4.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Aminotran_1_2 PF00155.21 EON31393.1 - 5.9e-64 216.5 0.0 6.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EON31393.1 - 2.2e-07 30.2 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 EON31393.1 - 6.7e-05 21.9 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Allinase DegT_DnrJ_EryC1 PF01041.17 EON31393.1 - 0.00013 21.5 0.1 0.00019 20.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EON31393.1 - 0.00014 20.5 0.0 0.00021 19.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NUDIX PF00293.28 EON31394.1 - 1.2e-22 80.3 0.0 1.6e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EON31394.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain DUF4232 PF14016.6 EON31394.1 - 0.06 13.5 0.1 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) DUF3487 PF11990.8 EON31395.1 - 0.027 14.3 0.7 0.03 14.2 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) OppC_N PF12911.7 EON31395.1 - 0.063 13.3 4.0 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2627 PF11118.8 EON31395.1 - 0.11 13.1 1.2 0.18 12.4 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) Astro_capsid_N PF03115.14 EON31395.1 - 0.12 11.0 0.1 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF4131 PF13567.6 EON31395.1 - 0.49 10.0 3.2 0.5 10.0 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PhoR PF11808.8 EON31395.1 - 2.1 8.8 8.2 2.8 8.4 8.2 1.3 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR FeoB_associated PF12669.7 EON31395.1 - 2.5 8.6 4.7 3.3 8.2 0.1 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF3742 PF12553.8 EON31395.1 - 9.7 6.3 6.6 13 6.0 6.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) DctQ PF04290.12 EON31396.1 - 0.024 14.5 0.4 0.024 14.5 0.4 3.9 2 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component PspC PF04024.12 EON31396.1 - 0.12 12.2 3.7 0.42 10.5 0.6 3.4 2 1 0 2 2 2 0 PspC domain DUF3792 PF12670.7 EON31396.1 - 0.51 10.5 0.1 0.51 10.5 0.1 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3792) TMEM154 PF15102.6 EON31397.1 - 0.0057 16.6 0.1 0.0096 15.8 0.1 1.4 1 1 1 2 2 2 1 TMEM154 protein family TSKS PF15358.6 EON31397.1 - 1.2 7.5 3.1 1.4 7.2 3.1 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate AAA_31 PF13614.6 EON31400.1 - 4.2e-35 121.2 0.0 5.7e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EON31400.1 - 3.7e-14 52.9 0.0 6.7e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EON31400.1 - 2.5e-10 40.2 0.0 0.00072 19.1 0.2 2.6 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EON31400.1 - 3e-08 33.4 0.7 3e-05 23.6 0.1 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 EON31400.1 - 0.0017 17.6 0.7 0.0027 16.9 0.7 1.5 1 1 0 1 1 1 1 Anion-transporting ATPase MipZ PF09140.11 EON31400.1 - 0.0072 15.6 0.1 3.5 6.8 0.0 2.1 1 1 1 2 2 2 2 ATPase MipZ Fer4_NifH PF00142.18 EON31400.1 - 0.013 15.0 0.1 0.028 13.9 0.1 1.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 EON31400.1 - 0.018 14.4 0.4 0.063 12.6 0.1 1.9 2 0 0 2 2 2 0 VirC1 protein SRP54 PF00448.22 EON31400.1 - 0.1 12.2 0.6 0.34 10.5 0.4 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Myco_19_kDa PF05481.12 EON31401.1 - 9.8e-37 125.8 6.3 1.3e-36 125.4 6.3 1.1 1 0 0 1 1 1 1 Mycobacterium 19 kDa lipoprotein antigen Transgly_assoc PF04226.13 EON31402.1 - 1.9e-12 47.3 13.8 1.9e-12 47.3 13.8 2.1 2 1 0 2 2 2 1 Transglycosylase associated protein DUF5518 PF17647.1 EON31402.1 - 0.0077 16.4 15.2 0.0094 16.1 15.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5518) BaxI_1 PF12811.7 EON31402.1 - 0.11 12.0 4.5 0.13 11.8 4.5 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like NiFe_hyd_3_EhaA PF17367.2 EON31402.1 - 1.5 9.0 5.4 1.1 9.4 2.0 2.1 1 1 1 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF1129 PF06570.11 EON31402.1 - 4.1 6.8 5.6 5.6 6.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) FeoB_C PF07664.12 EON31402.1 - 9.6 6.0 10.9 3 7.6 0.9 3.0 1 1 2 3 3 3 0 Ferrous iron transport protein B C terminus NAD_binding_10 PF13460.6 EON31403.1 - 9.2e-46 156.1 3.7 1e-45 155.9 3.7 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON31403.1 - 6.9e-10 38.9 0.2 1.1e-09 38.2 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EON31403.1 - 7.4e-05 22.3 0.4 0.00011 21.8 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EON31403.1 - 0.00018 21.8 0.3 0.00027 21.2 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EON31403.1 - 0.0054 17.3 0.1 0.0096 16.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 EON31403.1 - 0.0097 16.4 0.2 0.023 15.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase LpxI_N PF17930.1 EON31403.1 - 0.046 13.6 0.1 0.087 12.7 0.1 1.4 1 1 0 1 1 1 0 LpxI N-terminal domain SplA PF11132.8 EON31403.1 - 0.69 9.7 4.6 0.76 9.6 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator protein (SplA) FAD-oxidase_C PF02913.19 EON31404.1 - 7.4e-45 153.5 0.1 1e-44 153.0 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EON31404.1 - 2.4e-29 101.8 3.9 2.4e-29 101.8 3.9 2.3 3 0 0 3 3 3 1 FAD binding domain Glyco_hydro_77 PF02446.17 EON31405.1 - 3e-114 382.5 0.0 3.8e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase MFS_1 PF07690.16 EON31406.1 - 8.2e-34 117.1 92.6 8.2e-30 103.9 54.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON31406.1 - 9.5e-18 64.3 12.2 9.5e-18 64.3 12.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EON31406.1 - 1.2e-05 24.3 8.0 1.2e-05 24.3 8.0 2.4 2 1 1 3 3 3 1 MFS_1 like family PUCC PF03209.15 EON31406.1 - 0.00064 18.8 16.0 0.00064 18.8 16.0 2.7 2 1 1 3 3 3 1 PUCC protein Plasmid_stab_B PF10784.9 EON31406.1 - 3.9 7.4 5.1 52 3.8 0.1 3.5 4 0 0 4 4 4 0 Plasmid stability protein TRI12 PF06609.13 EON31406.1 - 9.9 4.4 21.4 0.21 10.0 12.0 2.2 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pyr_redox_3 PF13738.6 EON31407.1 - 3e-19 69.4 0.0 1.6e-18 67.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON31407.1 - 8.3e-19 67.4 0.0 2e-17 62.8 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON31407.1 - 1.4e-17 63.9 0.0 5.1e-15 55.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON31407.1 - 5e-11 42.3 0.0 2.3e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON31407.1 - 5.5e-11 42.6 1.4 1.7e-06 27.9 0.5 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON31407.1 - 6e-10 39.2 0.2 4.2e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON31407.1 - 1.3e-07 31.1 0.2 3e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EON31407.1 - 3.5e-05 24.3 0.4 0.15 12.6 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON31407.1 - 3.8e-05 23.2 0.3 6e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON31407.1 - 0.0002 20.7 0.6 0.001 18.3 0.0 2.3 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 EON31407.1 - 0.00036 19.9 0.7 0.003 16.9 0.3 2.3 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 EON31407.1 - 0.00051 20.1 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EON31407.1 - 0.0011 19.0 3.8 1.2 9.1 0.1 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.22 EON31407.1 - 0.0026 16.9 0.1 0.02 14.0 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EON31407.1 - 0.0073 15.1 0.3 0.21 10.3 0.4 2.4 2 0 0 2 2 2 1 HI0933-like protein SRAP PF02586.14 EON31408.1 - 8.5e-62 208.6 0.0 9.6e-62 208.4 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) tRNA_edit PF04073.15 EON31409.1 - 2.5e-26 92.2 0.2 3.3e-26 91.8 0.2 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HTH_31 PF13560.6 EON31409.1 - 2.7 8.4 5.8 5.2 7.5 0.4 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain Sigma70_r2 PF04542.14 EON31411.1 - 4.6e-18 64.7 0.1 9.5e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON31411.1 - 4.8e-17 61.4 0.0 1.2e-16 60.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON31411.1 - 1.6e-11 43.5 0.4 4.3e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 zf-HC2 PF13490.6 EON31412.1 - 1.4e-07 31.6 2.5 2.9e-07 30.6 2.5 1.6 1 0 0 1 1 1 1 Putative zinc-finger Biotin_lipoyl PF00364.22 EON31413.1 - 2.7e-16 59.1 5.5 3.2e-16 58.9 5.5 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EON31413.1 - 4.1e-07 29.7 4.6 4.8e-05 23.1 0.6 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EON31413.1 - 0.00011 22.9 2.8 0.0028 18.4 0.3 2.1 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 EON31413.1 - 0.0031 16.7 1.0 0.078 12.2 0.1 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 EON31413.1 - 0.023 14.4 0.6 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain PASTA PF03793.19 EON31413.1 - 0.028 14.3 0.2 5.4 6.9 0.1 2.1 2 0 0 2 2 2 0 PASTA domain GCV_H PF01597.19 EON31413.1 - 0.033 14.1 1.6 0.039 13.8 1.6 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 EON31413.1 - 0.058 13.6 0.8 0.77 10.0 0.8 2.1 1 1 0 1 1 1 0 Peptidase family M23 H_kinase_N PF12282.8 EON31414.1 - 7.1e-50 168.7 1.1 7.1e-50 168.7 1.1 2.0 2 0 0 2 2 2 1 Signal transduction histidine kinase HisKA_2 PF07568.12 EON31414.1 - 1.1e-23 83.1 2.0 2.7e-23 81.8 2.0 1.7 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 EON31414.1 - 2.8e-09 37.5 0.0 1.7e-08 35.0 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 EON31414.1 - 3.2e-08 34.1 1.6 3.2e-08 34.1 1.6 2.6 3 0 0 3 3 3 1 HWE histidine kinase HATPase_c_2 PF13581.6 EON31414.1 - 2.7e-06 27.4 0.3 4.4e-05 23.4 0.4 2.7 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 EON31414.1 - 0.00029 21.0 5.8 0.0014 18.8 0.6 3.7 3 1 0 3 3 3 1 PAS fold HATPase_c_3 PF13589.6 EON31414.1 - 0.033 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PBP_like PF12727.7 EON31414.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PBP superfamily domain Whib PF02467.16 EON31415.1 - 2.6e-26 92.0 0.8 3.1e-26 91.7 0.8 1.1 1 0 0 1 1 1 1 Transcription factor WhiB MFS_1 PF07690.16 EON31416.1 - 3.7e-19 68.9 34.5 3.7e-19 68.9 34.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 EON31416.1 - 0.1 11.4 0.7 0.18 10.5 0.7 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter DAGK_cat PF00781.24 EON31417.1 - 1.1e-23 83.2 0.0 1.8e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain L6_membrane PF05805.12 EON31418.1 - 0.84 9.2 4.1 0.56 9.8 2.7 1.4 1 1 0 1 1 1 0 L6 membrane protein DUF2127 PF09900.9 EON31418.1 - 1.1 9.5 10.3 0.82 9.9 5.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2127) DUF4233 PF14017.6 EON31418.1 - 4.5 7.7 14.4 29 5.1 14.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Sugar_tr PF00083.24 EON31418.1 - 7.1 5.4 10.9 0.19 10.5 2.7 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter AAA_31 PF13614.6 EON31419.1 - 9.2e-56 188.5 0.0 2.1e-54 184.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EON31419.1 - 3.1e-23 82.2 0.0 5.3e-23 81.5 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EON31419.1 - 4.7e-12 45.9 0.1 6.2e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EON31419.1 - 4.8e-09 36.0 0.1 1e-08 35.0 0.1 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EON31419.1 - 1.7e-08 34.1 0.5 0.0018 17.6 0.0 2.5 2 1 0 3 3 3 2 ATPase MipZ ArsA_ATPase PF02374.15 EON31419.1 - 2e-07 30.5 0.4 1e-06 28.2 0.4 2.1 1 1 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EON31419.1 - 0.00043 19.8 0.0 0.049 13.1 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Glyco_trans_4_4 PF13579.6 EON31419.1 - 0.015 15.7 0.6 0.027 14.9 0.6 1.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain T2SS-T3SS_pil_N PF13629.6 EON31419.1 - 0.064 13.0 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Pilus formation protein N terminal region VirC1 PF07015.11 EON31419.1 - 0.094 12.0 0.1 4.2 6.6 0.1 2.1 2 0 0 2 2 2 0 VirC1 protein PQQ_2 PF13360.6 EON31420.1 - 0.00023 20.9 4.2 0.00096 18.8 2.0 2.5 2 1 0 2 2 2 1 PQQ-like domain Big_9 PF17963.1 EON31420.1 - 0.61 10.9 7.1 2 9.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial Ig domain DEAD PF00270.29 EON31421.1 - 5e-48 163.2 0.0 3.2e-46 157.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON31421.1 - 4.5e-30 104.2 0.1 9.5e-30 103.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON31421.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LytR_C PF13399.6 EON31421.1 - 0.61 11.1 3.7 0.84 10.7 0.1 3.0 3 1 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator MiaE_2 PF13794.6 EON31422.1 - 4.4e-52 176.5 3.9 5.4e-52 176.2 3.9 1.1 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF3107 PF11305.8 EON31423.1 - 1e-27 96.2 0.1 1.1e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) TetR_N PF00440.23 EON31424.1 - 1.6e-18 66.2 0.0 2.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON31424.1 - 0.00014 22.0 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase TetR_C_33 PF13305.6 EON31424.1 - 0.0048 17.6 1.1 0.007 17.1 0.1 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EON31424.1 - 0.073 13.8 0.1 0.3 11.9 0.0 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3152 PF11350.8 EON31425.1 - 1.8e-89 299.0 0.0 2.2e-89 298.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3152) ThiF PF00899.21 EON31426.1 - 9.3e-59 198.7 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EON31426.1 - 2.7e-13 50.4 0.0 8e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EON31426.1 - 0.016 15.3 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 EON31426.1 - 0.089 12.3 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 EON31428.1 - 5.5e-13 48.6 44.8 5.5e-13 48.6 44.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 EON31429.1 - 3.1e-44 151.4 0.3 5.6e-44 150.5 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EON31429.1 - 2.2e-17 63.0 0.0 5.7e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 EON31429.1 - 3.6e-16 59.3 13.1 1.6e-10 41.2 9.4 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 EON31429.1 - 1.3e-12 48.1 0.7 3.8e-12 46.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 EON31429.1 - 3.6e-12 46.0 0.3 1.5e-11 43.9 0.0 2.3 3 0 0 3 3 3 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EON31429.1 - 3.7e-10 39.6 0.1 8.8e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain GIDA PF01134.22 EON31429.1 - 0.0012 18.1 0.1 0.46 9.5 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON31429.1 - 0.0012 18.9 0.1 0.0012 18.9 0.1 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EON31429.1 - 0.0014 18.0 0.0 0.012 14.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EON31429.1 - 0.0024 17.2 3.2 0.23 10.7 0.2 2.4 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EON31429.1 - 0.0028 17.3 3.7 0.028 14.0 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON31429.1 - 0.3 9.7 1.4 16 4.0 0.0 2.8 4 0 0 4 4 4 0 HI0933-like protein Rieske_2 PF13806.6 EON31430.1 - 6.8e-29 99.9 0.0 9.4e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain HEM4 PF02602.15 EON31431.1 - 4.2e-41 140.8 0.2 5.5e-41 140.4 0.2 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Trans_reg_C PF00486.28 EON31431.1 - 9.8e-15 54.4 0.0 2.3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal CbiX PF01903.17 EON31432.1 - 3.2e-24 85.3 0.5 2.6e-13 50.2 0.0 2.9 2 1 0 2 2 2 2 CbiX DNA_binding_1 PF01035.20 EON31433.1 - 1.6e-16 60.2 0.1 1.9e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_6 PF12697.7 EON31434.1 - 4.6e-22 79.7 20.8 5.4e-22 79.5 20.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON31434.1 - 4.7e-18 65.8 0.1 8.1e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON31434.1 - 8.3e-16 58.0 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EON31434.1 - 1.5e-06 28.2 0.2 2.1e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EON31434.1 - 4.3e-06 26.6 0.0 6.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 EON31434.1 - 5.5e-06 26.3 0.6 1.2e-05 25.2 0.1 2.0 2 1 0 2 2 2 1 Serine hydrolase Peptidase_S9 PF00326.21 EON31434.1 - 6e-05 22.6 0.0 0.00015 21.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 EON31434.1 - 6.6e-05 23.1 0.1 0.00012 22.3 0.1 1.7 1 1 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 EON31434.1 - 7.7e-05 22.4 0.0 0.0001 21.9 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EON31434.1 - 0.002 17.9 0.0 0.0077 16.0 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.7 EON31434.1 - 0.0037 16.2 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EON31434.1 - 0.0044 16.8 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EON31434.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) AXE1 PF05448.12 EON31434.1 - 0.032 12.9 0.0 0.071 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 EON31434.1 - 0.034 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2920 PF11144.8 EON31434.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF2974 PF11187.8 EON31434.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PAF-AH_p_II PF03403.13 EON31434.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 EON31434.1 - 0.13 12.1 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 1 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EON31434.1 - 0.15 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF1057 PF06342.12 EON31434.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase PF07224.11 EON31434.1 - 0.2 10.7 0.0 0.48 9.4 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.11 EON31434.1 - 0.23 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LCAT PF02450.15 EON31434.1 - 0.31 10.2 0.0 0.43 9.7 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PDDEXK_1 PF12705.7 EON31435.1 - 2e-36 126.3 0.0 3.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD-helicase PF00580.21 EON31435.1 - 3e-28 99.3 0.0 5.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EON31435.1 - 7.1e-13 48.6 0.0 2.8e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EON31435.1 - 7.6e-13 49.0 0.0 1.4e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EON31435.1 - 0.00066 19.5 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EON31435.1 - 0.00092 19.0 0.9 0.0041 16.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EON31435.1 - 0.016 15.5 0.0 9.9 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EON31435.1 - 0.037 13.8 4.6 0.25 11.2 0.7 2.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EON31435.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_12 PF13087.6 EON31435.1 - 0.22 11.1 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 EON31435.1 - 0.97 9.7 11.5 0.39 11.0 1.8 4.8 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain AAA_16 PF13191.6 EON31435.1 - 5.5 7.3 14.8 2.7 8.4 5.3 4.2 4 1 0 4 4 4 0 AAA ATPase domain UvrD-helicase PF00580.21 EON31436.1 - 1.5e-44 152.8 0.0 2e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EON31436.1 - 6.1e-34 117.9 0.0 7.4e-33 114.4 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EON31436.1 - 8.2e-20 71.6 0.0 1.9e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 EON31436.1 - 7.3e-13 49.0 0.0 2.8e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD_C_2 PF13538.6 EON31436.1 - 2.2e-10 40.2 0.8 0.00024 20.9 0.1 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EON31436.1 - 0.0018 18.0 0.0 0.0064 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EON31436.1 - 0.066 12.9 0.3 7.8 6.2 0.1 2.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EON31436.1 - 0.067 12.8 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain TrkA_N PF02254.18 EON31437.1 - 3.8e-27 94.9 3.3 5.7e-27 94.3 3.3 1.3 1 0 0 1 1 1 1 TrkA-N domain Ion_trans_2 PF07885.16 EON31437.1 - 5.6e-14 51.9 4.1 1.2e-13 50.8 4.1 1.6 1 0 0 1 1 1 1 Ion channel BATS PF06968.13 EON31437.1 - 0.013 15.7 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain IlvN PF07991.12 EON31437.1 - 0.088 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ion_trans PF00520.31 EON31437.1 - 0.13 11.4 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 Ion transport protein NUDIX PF00293.28 EON31438.1 - 1.6e-18 67.0 0.3 9.9e-18 64.4 0.2 2.0 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 EON31438.1 - 0.0024 18.5 1.4 0.0071 17.0 1.3 1.8 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EON31438.1 - 0.021 14.5 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Glutaredoxin PF00462.24 EON31439.1 - 4.6e-09 36.4 0.0 6.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EON31439.1 - 0.0014 19.0 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EON31439.1 - 0.0063 17.0 0.0 0.044 14.2 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like domain PAM2 PF07145.15 EON31439.1 - 0.042 13.5 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region UvrD-helicase PF00580.21 EON31440.1 - 1.2e-46 159.7 0.0 1.1e-43 149.9 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EON31440.1 - 7.6e-39 133.4 0.0 1.4e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EON31440.1 - 5.1e-38 131.3 0.0 1.4e-22 80.6 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain HRDC PF00570.23 EON31440.1 - 8.2e-21 73.8 0.0 1.9e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 HRDC domain UvrD_C_2 PF13538.6 EON31440.1 - 1.7e-10 40.5 0.2 1.4e-09 37.7 0.2 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EON31440.1 - 1.2e-05 25.2 0.9 8.8e-05 22.3 0.2 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EON31440.1 - 1.8e-05 24.6 0.2 0.044 13.5 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase TF_Zn_Ribbon PF08271.12 EON31440.1 - 0.18 11.3 0.2 0.36 10.4 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Whib PF02467.16 EON31442.1 - 5.8e-16 58.8 0.5 8.1e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 Transcription factor WhiB AT_hook PF02178.19 EON31442.1 - 0.011 15.5 5.1 0.02 14.7 5.1 1.4 1 0 0 1 1 1 0 AT hook motif ABC1 PF03109.16 EON31443.1 - 2.8e-29 101.7 0.0 4.6e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EON31443.1 - 5.6e-07 29.7 3.9 9.3e-06 25.7 0.4 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family WaaY PF06176.11 EON31443.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Zincin_2 PF10103.9 EON31445.1 - 1.8e-109 366.0 3.7 1.8e-109 366.0 3.7 1.3 2 0 0 2 2 2 1 Zincin-like metallopeptidase PDZ_2 PF13180.6 EON31446.1 - 6.3e-11 42.4 0.1 1.7e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Lon_C PF05362.13 EON31446.1 - 2.2e-09 37.2 0.3 4.2e-09 36.3 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain PDZ_6 PF17820.1 EON31446.1 - 2.8e-05 23.9 1.7 6.5e-05 22.7 1.7 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EON31446.1 - 0.0052 17.1 0.1 0.015 15.7 0.1 1.8 1 1 0 1 1 1 1 PDZ domain UPF0182 PF03699.13 EON31448.1 - 3.4e-261 868.7 0.1 4.3e-261 868.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) Phage_holin_3_6 PF07332.11 EON31449.1 - 0.0054 16.8 0.6 0.0066 16.5 0.6 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4231 PF14015.6 EON31449.1 - 0.041 14.4 0.2 0.047 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3325 PF11804.8 EON31449.1 - 1.2 9.3 13.2 9.9 6.4 10.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) FA_hydroxylase PF04116.13 EON31449.1 - 3.9 7.8 12.1 32 4.8 12.4 1.8 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily TfoX_N PF04993.13 EON31450.1 - 1.5e-13 50.8 0.0 1.7e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 TfoX N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON31451.1 - 1.3e-31 109.9 0.7 2.7e-31 108.8 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON31451.1 - 7e-22 77.5 0.2 1.2e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31451.1 - 1.7e-05 25.1 0.5 1.7e-05 25.1 0.5 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain LIP PF03583.14 EON31453.1 - 1.8e-07 30.8 0.0 3.4e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.7 EON31453.1 - 0.0005 20.7 18.8 0.0005 20.7 18.8 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31453.1 - 0.00067 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RDD PF06271.12 EON31454.1 - 1.1e-13 51.7 2.3 1.5e-13 51.1 2.3 1.2 1 0 0 1 1 1 1 RDD family SpoIIM PF01944.17 EON31455.1 - 3.3e-32 111.7 8.3 5.2e-32 111.0 8.3 1.3 1 0 0 1 1 1 1 Stage II sporulation protein M DUF294_C PF10335.9 EON31455.1 - 0.048 13.4 0.2 0.085 12.6 0.2 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain DoxX PF07681.12 EON31456.1 - 0.0068 17.0 2.6 0.0086 16.6 2.6 1.1 1 0 0 1 1 1 1 DoxX DoxX_3 PF13781.6 EON31456.1 - 0.041 14.5 0.7 0.058 14.0 0.7 1.4 1 1 0 1 1 1 0 DoxX-like family DUF58 PF01882.18 EON31457.1 - 3.7e-20 72.0 1.1 7.9e-20 70.9 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 DUF11 PF01345.18 EON31457.1 - 6.3e-05 23.2 2.1 0.00017 21.8 2.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF11 ASH PF15780.5 EON31457.1 - 0.0011 19.1 0.2 0.0032 17.6 0.1 1.7 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin VWA_2 PF13519.6 EON31457.1 - 0.0068 17.0 0.6 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain FCD PF07729.12 EON31457.1 - 0.014 15.8 1.1 0.21 12.0 0.2 2.5 2 0 0 2 2 2 0 FCD domain AAA_3 PF07726.11 EON31458.1 - 4.1e-63 211.1 0.0 6.1e-63 210.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EON31458.1 - 1e-20 73.3 0.1 2e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 EON31458.1 - 1.4e-13 51.0 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 EON31458.1 - 6.1e-05 22.2 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EON31458.1 - 0.00019 21.2 0.0 0.00092 19.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 EON31458.1 - 0.00028 20.7 0.0 0.0015 18.3 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EON31458.1 - 0.00073 20.0 0.0 0.0017 18.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EON31458.1 - 0.00078 18.9 0.5 0.014 14.7 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EON31458.1 - 0.089 13.2 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF4350 PF14258.6 EON31459.1 - 2.9e-10 40.4 0.3 1.1e-09 38.6 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) Mycobact_memb PF05423.13 EON31459.1 - 0.056 13.4 0.7 0.056 13.4 0.7 1.9 3 0 0 3 3 3 0 Mycobacterium membrane protein DFP PF04127.15 EON31459.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Phage_holin_3_6 PF07332.11 EON31459.1 - 3.2 7.8 8.2 3 7.9 0.8 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4381 PF14316.6 EON31459.1 - 6 7.1 7.4 46 4.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) RskA PF10099.9 EON31459.1 - 6.9 6.9 18.5 0.21 11.8 0.5 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF4129 PF13559.6 EON31460.1 - 2.5e-09 37.3 6.1 2.5e-09 37.3 6.1 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4129) GPDPase_memb PF10110.9 EON31461.1 - 2.6e-08 33.0 1.9 4.9e-08 32.1 1.9 1.5 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Cyt_bd_oxida_II PF02322.15 EON31461.1 - 1.1 8.5 37.4 5.3e+02 -0.3 37.3 2.8 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II SnoaL_2 PF12680.7 EON31462.1 - 7.6e-11 42.6 0.2 9.7e-11 42.2 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON31462.1 - 0.00026 21.4 0.5 0.00038 20.8 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 EON31462.1 - 0.00047 20.7 0.0 0.001 19.6 0.0 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 EON31462.1 - 0.0024 18.0 0.1 0.0045 17.1 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EON31462.1 - 0.11 12.3 0.0 0.59 9.9 0.0 2.0 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase adh_short PF00106.25 EON31463.1 - 8.2e-40 136.3 0.0 9.6e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31463.1 - 7.3e-26 91.2 0.0 9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31463.1 - 7.3e-09 35.8 0.0 9.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON31463.1 - 2.6e-05 24.2 0.4 3.6e-05 23.7 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_100 PF12899.7 EON31464.1 - 0.0003 19.6 0.3 0.00045 19.0 0.3 1.2 1 0 0 1 1 1 1 Alkaline and neutral invertase TetR_N PF00440.23 EON31465.1 - 1.4e-16 60.0 0.0 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON31465.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 EON31465.1 - 0.067 13.0 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 EON31465.1 - 0.17 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Phage_holin_3_6 PF07332.11 EON31466.1 - 0.32 11.0 5.8 0.45 10.6 5.8 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Whib PF02467.16 EON31467.1 - 5.4e-09 36.5 0.1 1.2e-08 35.4 0.0 1.6 1 1 1 2 2 2 1 Transcription factor WhiB EutQ PF06249.12 EON31468.1 - 1.4e-13 50.9 0.0 1.6e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EON31468.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EON31468.1 - 0.0028 17.3 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain YopX PF09643.10 EON31468.1 - 0.063 13.3 0.1 11 6.1 0.0 2.2 2 0 0 2 2 2 0 YopX protein Fer2 PF00111.27 EON31470.1 - 5.3e-12 45.5 0.2 9.2e-12 44.8 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON31470.1 - 2.8e-08 34.4 0.0 1.6e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON31470.1 - 3.9e-05 23.8 0.0 0.0069 16.5 0.1 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Fer2_4 PF13510.6 EON31470.1 - 0.0022 18.0 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 EON31470.1 - 0.0061 16.9 0.0 0.04 14.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain DUF3445 PF11927.8 EON31471.1 - 1.7e-52 178.3 0.0 2.4e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fer2 PF00111.27 EON31472.1 - 3e-11 43.1 0.4 6.2e-11 42.1 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON31472.1 - 0.00014 22.4 0.0 0.00083 20.0 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON31472.1 - 0.0039 17.3 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_4 PF13510.6 EON31472.1 - 0.032 14.3 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF3445 PF11927.8 EON31473.1 - 9.2e-47 159.6 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ammonium_transp PF00909.21 EON31474.1 - 1.3e-107 359.9 38.5 1.5e-107 359.7 38.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Gln-synt_C PF00120.24 EON31475.1 - 1.1e-84 284.3 0.0 1.9e-84 283.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EON31475.1 - 3.7e-05 23.4 0.0 9.1e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain GATase_6 PF13522.6 EON31476.1 - 6.9e-17 61.9 0.2 1.3e-16 61.0 0.2 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EON31476.1 - 2.4e-16 59.7 0.0 3.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GXGXG PF01493.19 EON31477.1 - 2.3e-11 43.6 15.6 9.6e-11 41.6 15.6 2.0 1 1 0 1 1 1 1 GXGXG motif Glu_synthase PF01645.17 EON31478.1 - 2.2e-87 293.6 0.4 2.6e-81 273.6 0.8 2.0 2 0 0 2 2 2 2 Conserved region in glutamate synthase FMN_dh PF01070.18 EON31478.1 - 1.8e-16 60.1 4.9 6.9e-16 58.2 1.5 2.5 3 0 0 3 3 3 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EON31478.1 - 5.4e-11 42.1 3.5 9.3e-11 41.3 3.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EON31478.1 - 3.6e-10 39.7 7.7 7.2e-10 38.8 7.6 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EON31478.1 - 0.00027 20.5 1.1 0.00045 19.7 0.2 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EON31478.1 - 0.0003 20.2 0.4 0.0006 19.2 0.4 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EON31478.1 - 0.0014 17.9 0.4 0.0014 17.9 0.4 1.9 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase QRPTase_C PF01729.19 EON31478.1 - 0.0061 16.4 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Glu_syn_central PF04898.14 EON31478.1 - 0.0073 15.8 0.2 0.012 15.1 0.2 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain PcrB PF01884.17 EON31478.1 - 0.094 12.2 3.5 0.2 11.1 1.0 2.1 1 1 1 2 2 2 0 PcrB family G3P_antiterm PF04309.12 EON31478.1 - 0.37 10.2 1.4 0.46 9.9 0.2 1.8 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DAO PF01266.24 EON31479.1 - 3e-58 198.1 5.1 3.4e-58 197.9 5.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON31479.1 - 6.4e-08 32.2 6.5 7.5e-06 25.4 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON31479.1 - 1.2e-07 31.2 13.7 4.4e-07 29.3 13.7 1.8 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EON31479.1 - 2.6e-07 30.1 4.7 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EON31479.1 - 8.9e-06 25.3 13.0 0.00013 21.5 13.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON31479.1 - 2.4e-05 23.7 1.4 0.05 12.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON31479.1 - 2.7e-05 23.2 10.8 0.00077 18.4 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 EON31479.1 - 2.9e-05 23.0 3.5 0.00029 19.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EON31479.1 - 4.1e-05 23.1 1.4 0.00075 18.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EON31479.1 - 5e-05 23.3 7.5 0.0036 17.3 0.5 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EON31479.1 - 8.4e-05 23.1 2.7 0.23 12.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON31479.1 - 0.00016 21.1 11.7 0.0072 15.6 11.7 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON31479.1 - 0.00072 19.7 4.4 0.00072 19.7 4.4 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 EON31479.1 - 0.021 14.2 0.6 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.17 EON31479.1 - 0.027 13.7 6.0 0.14 11.4 2.9 2.2 2 0 0 2 2 2 0 Thi4 family Transglut_core PF01841.19 EON31479.1 - 0.11 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily HTH_31 PF13560.6 EON31480.1 - 3.7e-12 46.4 0.1 6.1e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EON31480.1 - 4.5e-12 45.8 0.0 6.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EON31480.1 - 9.1e-11 41.6 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 EON31480.1 - 2.6e-08 33.5 0.7 5e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 Cupin domain HTH_37 PF13744.6 EON31480.1 - 7.3e-07 29.1 0.1 1.1e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EON31480.1 - 3.1e-05 24.3 0.0 5.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EON31480.1 - 0.00031 20.5 0.1 0.00089 19.1 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 EON31480.1 - 0.026 14.5 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 MarR family Cupin_3 PF05899.12 EON31480.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EthD PF07110.11 EON31481.1 - 2.5e-06 28.5 0.4 7.9e-06 26.9 0.1 2.0 2 1 0 2 2 2 1 EthD domain MmlI PF09448.10 EON31481.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.6 1 1 1 2 2 2 0 Methylmuconolactone methyl-isomerase MFS_1 PF07690.16 EON31482.1 - 3.7e-33 114.9 81.0 1.7e-32 112.7 47.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON31482.1 - 4.3e-07 29.2 9.4 4.3e-07 29.2 9.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter CnrY PF17524.2 EON31482.1 - 4 7.7 11.0 0.97 9.7 0.1 3.3 3 0 0 3 3 3 0 Anti-sigma factor CnrY MarR PF01047.22 EON31483.1 - 2.6e-14 52.9 0.0 6.1e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EON31483.1 - 3e-09 36.6 0.3 1.3e-08 34.6 0.1 2.2 1 1 1 2 2 2 1 MarR family HTH_27 PF13463.6 EON31483.1 - 0.00017 22.0 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EON31483.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SMC_ScpB PF04079.16 EON31483.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.3 1 1 0 1 1 1 0 Segregation and condensation complex subunit ScpB HxlR PF01638.17 EON31483.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF839 PF05787.13 EON31484.1 - 1.2e-151 506.5 0.2 1.4e-151 506.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 EON31484.1 - 0.0071 16.1 5.3 0.0071 16.1 5.3 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Reg_prop PF07494.11 EON31484.1 - 0.11 12.8 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Two component regulator propeller TPM_phosphatase PF04536.14 EON31485.1 - 2.1e-20 73.1 0.1 4.8e-20 72.0 0.1 1.7 1 0 0 1 1 1 1 TPM domain DUF948 PF06103.11 EON31485.1 - 0.89 9.9 4.9 22 5.4 0.1 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) kleA_kleC PF17383.2 EON31485.1 - 5.5 7.4 9.7 25 5.3 1.2 3.8 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Bac_luciferase PF00296.20 EON31486.1 - 4.2e-34 118.4 0.1 2e-33 116.2 0.1 1.8 1 1 0 1 1 1 1 Luciferase-like monooxygenase Methyltransf_25 PF13649.6 EON31487.1 - 4.1e-11 43.4 0.0 9.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EON31487.1 - 1.6e-10 41.1 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 EON31487.1 - 1.7e-09 38.2 0.0 3.3e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON31487.1 - 7.5e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON31487.1 - 5.8e-06 27.0 0.1 2.6e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON31487.1 - 8.2e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain TehB PF03848.14 EON31487.1 - 9.3e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EON31487.1 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EON31487.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EON31487.1 - 0.015 14.4 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PGAP1 PF07819.13 EON31488.1 - 7e-10 39.0 0.0 4.3e-09 36.4 0.0 2.0 3 0 0 3 3 3 1 PGAP1-like protein DUF676 PF05057.14 EON31488.1 - 2.4e-07 30.5 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EON31488.1 - 4.6e-05 24.1 12.7 4.6e-05 24.1 12.7 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 EON31488.1 - 0.0044 16.3 0.0 0.0093 15.2 0.0 1.4 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EON31488.1 - 0.0048 16.2 0.7 0.0083 15.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF726 PF05277.12 EON31488.1 - 0.005 15.8 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Palm_thioest PF02089.15 EON31488.1 - 0.025 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 EON31488.1 - 0.058 12.9 0.1 0.27 10.7 0.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EON31488.1 - 0.12 11.9 0.0 0.4 10.3 0.1 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EON31488.1 - 0.2 11.7 0.5 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain LapA_dom PF06305.11 EON31489.1 - 7.1e-08 32.1 0.1 7.1e-08 32.1 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 EON31489.1 - 0.021 14.9 2.1 0.025 14.6 2.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF202 PF02656.15 EON31489.1 - 0.077 13.5 6.9 0.15 12.5 6.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4131 PF13567.6 EON31489.1 - 0.1 12.3 2.5 0.1 12.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3188 PF11384.8 EON31489.1 - 0.1 12.3 0.7 2.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF2663 PF10864.8 EON31489.1 - 0.15 12.5 0.8 0.16 12.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF997 PF06196.12 EON31489.1 - 0.21 11.6 10.0 0.67 10.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF997) Mn_catalase PF05067.12 EON31490.1 - 7.3e-71 238.4 0.0 8.9e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Manganese containing catalase Ferritin-like PF12902.7 EON31490.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like ILVD_EDD PF00920.21 EON31491.1 - 4.3e-212 705.3 0.7 4.9e-212 705.1 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.7 EON31492.1 - 2.8e-20 73.9 5.4 3.8e-20 73.4 5.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31492.1 - 4.6e-08 32.6 0.0 0.0017 17.7 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON31492.1 - 9.3e-05 22.2 1.0 1.4 8.5 0.2 3.2 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EON31492.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EON31492.1 - 0.017 14.9 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 EON31492.1 - 0.12 12.1 0.7 0.64 9.7 0.4 1.9 1 1 1 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 EON31492.1 - 0.13 12.3 0.3 0.51 10.4 0.2 2.0 2 1 0 2 2 2 0 Thioesterase domain Git3 PF11710.8 EON31493.1 - 0.00019 21.3 0.1 0.00037 20.3 0.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF2593 PF10767.9 EON31493.1 - 0.021 14.9 3.2 2.3 8.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) DUF3290 PF11694.8 EON31493.1 - 0.11 12.4 0.1 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) COX7a PF02238.15 EON31493.1 - 0.24 11.8 2.1 3.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Ni_hydr_CYTB PF01292.20 EON31493.1 - 0.42 10.2 6.0 0.98 9.0 0.3 2.3 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 CD20 PF04103.15 EON31493.1 - 0.43 10.6 3.6 2.8 8.0 0.0 2.8 2 1 1 3 3 3 0 CD20-like family HTH_18 PF12833.7 EON31494.1 - 6.9e-15 55.1 0.0 1.8e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain AraC_binding_2 PF14525.6 EON31494.1 - 1.3e-08 34.7 0.4 2.4e-08 33.8 0.4 1.4 1 0 0 1 1 1 1 AraC-binding-like domain HTH_AraC PF00165.23 EON31494.1 - 0.00067 19.7 0.0 0.0022 18.1 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EON31495.1 - 4.5e-15 55.7 1.4 8e-15 54.9 1.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON31495.1 - 4.6e-08 33.0 0.0 8.9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 EON31495.1 - 0.0053 16.5 2.7 0.0095 15.6 2.7 1.5 1 0 0 1 1 1 1 AraC-binding-like domain UTRA PF07702.13 EON31496.1 - 3.7e-28 98.1 0.7 5.5e-28 97.6 0.7 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 EON31496.1 - 2.6e-13 49.4 0.1 4.6e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 EON31496.1 - 0.0064 16.2 0.2 0.017 14.8 0.2 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Fer4_7 PF12838.7 EON31497.1 - 1.2e-09 38.6 19.2 6.3e-08 33.1 10.3 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EON31497.1 - 8.2e-09 34.9 15.2 4.6e-05 23.1 2.4 3.0 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EON31497.1 - 1.7e-07 31.3 16.5 1.8e-06 28.0 8.5 1.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON31497.1 - 5e-07 29.5 13.5 2.6e-06 27.3 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EON31497.1 - 4.9e-06 26.6 10.1 1.3e-05 25.2 10.4 1.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EON31497.1 - 5.2e-06 26.5 10.9 0.0036 17.4 3.8 2.0 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EON31497.1 - 1.7e-05 25.7 7.0 0.043 14.8 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 EON31497.1 - 0.00022 21.9 17.0 0.019 15.9 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EON31497.1 - 0.0003 20.7 12.8 0.0012 18.9 2.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 EON31497.1 - 0.024 15.2 10.3 2.9 8.5 10.3 2.2 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 EON31497.1 - 0.031 14.8 11.3 0.1 13.1 1.5 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EON31497.1 - 0.095 13.4 2.0 0.095 13.4 2.0 2.2 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 EON31497.1 - 0.095 13.2 11.7 0.26 11.8 2.2 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EON31497.1 - 0.23 12.3 7.5 5.5 7.9 0.3 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EON31497.1 - 0.54 10.5 10.1 2.5 8.3 2.4 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain NMT1 PF09084.11 EON31498.1 - 4.4e-13 49.7 0.0 7.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON31498.1 - 1e-06 28.6 0.7 3e-06 27.1 0.7 1.8 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EON31498.1 - 1.1e-06 28.5 0.7 1.9e-06 27.7 0.7 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EON31498.1 - 9.5e-05 21.9 0.0 0.00031 20.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 EON31498.1 - 0.00049 19.6 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family BPD_transp_1 PF00528.22 EON31499.1 - 8.9e-16 58.2 13.8 1.5e-15 57.4 13.8 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EON31500.1 - 5.9e-28 98.1 0.0 9.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EON31500.1 - 1.2e-06 29.0 0.1 2e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EON31500.1 - 4.7e-06 26.6 0.0 8.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON31500.1 - 5.4e-05 22.9 0.2 0.00016 21.4 0.2 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EON31500.1 - 5.6e-05 23.4 0.0 9.7e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON31500.1 - 0.00012 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 EON31500.1 - 0.00012 22.3 0.0 0.0045 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EON31500.1 - 0.0003 21.2 0.0 0.0016 18.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EON31500.1 - 0.00037 19.6 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EON31500.1 - 0.00048 20.7 0.1 0.00074 20.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON31500.1 - 0.0009 19.0 0.2 0.0039 16.9 0.1 1.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EON31500.1 - 0.0012 18.8 0.3 0.0077 16.2 0.1 2.2 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EON31500.1 - 0.0013 18.7 0.0 0.0032 17.4 0.1 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 EON31500.1 - 0.0014 19.2 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EON31500.1 - 0.0027 17.7 0.1 0.016 15.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EON31500.1 - 0.0029 17.8 0.0 0.0093 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EON31500.1 - 0.0034 17.3 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EON31500.1 - 0.0035 16.7 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EON31500.1 - 0.0054 16.3 0.4 0.01 15.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EON31500.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 EON31500.1 - 0.0059 16.5 0.0 0.025 14.5 0.1 1.8 2 0 0 2 2 2 1 NTPase MeaB PF03308.16 EON31500.1 - 0.015 14.3 0.7 0.061 12.3 0.4 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EON31500.1 - 0.019 15.0 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EON31500.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase SMC_N PF02463.19 EON31500.1 - 0.041 13.3 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain CbiA PF01656.23 EON31500.1 - 0.045 13.8 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adeno_IVa2 PF02456.15 EON31500.1 - 0.052 12.4 0.2 0.15 10.8 0.2 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 EON31500.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EON31500.1 - 0.076 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EON31500.1 - 0.089 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 EON31500.1 - 0.099 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_27 PF13514.6 EON31500.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EON31500.1 - 0.13 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 EON31500.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EON31500.1 - 0.17 11.0 0.2 0.3 10.2 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 EON31500.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_ATPase PF09818.9 EON31500.1 - 0.2 10.4 0.2 0.37 9.5 0.2 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Viral_helicase1 PF01443.18 EON31500.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EON31500.1 - 0.22 10.8 0.2 0.52 9.6 0.1 1.6 2 0 0 2 2 2 0 KaiC FAD_binding_2 PF00890.24 EON31501.1 - 1.4e-37 129.7 1.9 2.4e-37 129.0 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain HEAT_2 PF13646.6 EON31501.1 - 5.2e-25 87.6 23.4 1.8e-09 37.9 9.3 4.7 1 1 2 4 4 4 4 HEAT repeats HEAT PF02985.22 EON31501.1 - 3.3e-16 58.0 15.2 0.76 10.2 0.0 9.6 9 0 0 9 9 9 4 HEAT repeat Succ_DH_flav_C PF02910.20 EON31501.1 - 8.4e-13 48.4 0.0 1.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EON31501.1 - 5.2e-11 42.3 1.6 6.4e-06 25.6 0.6 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON31501.1 - 8.3e-08 32.0 4.7 2.7e-07 30.3 4.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON31501.1 - 2.4e-07 29.8 0.4 4.8e-07 28.8 0.4 1.5 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EON31501.1 - 1.3e-06 27.7 1.5 1.8e-05 24.0 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EON31501.1 - 5.1e-05 22.7 0.6 8.9e-05 21.9 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EON31501.1 - 0.00022 20.6 1.9 0.0005 19.4 1.9 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON31501.1 - 0.00027 20.6 7.4 0.00034 20.3 2.8 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Cnd1 PF12717.7 EON31501.1 - 0.00064 19.8 1.3 2.5 8.1 0.0 3.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 NAD_binding_8 PF13450.6 EON31501.1 - 0.0034 17.6 0.8 0.012 15.8 0.8 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Cohesin_HEAT PF12765.7 EON31501.1 - 0.047 14.0 9.0 2.8 8.3 0.3 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion 3HCDH_N PF02737.18 EON31501.1 - 0.055 13.4 2.6 0.055 13.4 0.7 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EON31501.1 - 0.069 13.4 1.1 13 6.0 0.1 2.7 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 EON31501.1 - 0.076 11.8 0.7 0.12 11.2 0.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Adaptin_N PF01602.20 EON31501.1 - 0.12 10.9 0.0 0.5 8.9 0.0 1.7 1 1 0 2 2 2 0 Adaptin N terminal region Pyr_redox_3 PF13738.6 EON31501.1 - 0.19 10.9 1.6 0.24 10.6 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HEAT_EZ PF13513.6 EON31501.1 - 0.26 11.9 23.4 4.3 8.0 3.3 7.4 7 1 1 8 8 8 0 HEAT-like repeat NAD_binding_7 PF13241.6 EON31501.1 - 0.27 11.7 4.0 0.56 10.7 0.1 2.9 4 0 0 4 4 2 0 Putative NAD(P)-binding HEAT_PBS PF03130.16 EON31501.1 - 7.2 7.6 20.4 3.2 8.7 0.9 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat adh_short PF00106.25 EON31502.1 - 6e-55 185.7 0.3 7.4e-55 185.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31502.1 - 1.5e-42 145.7 3.1 1.9e-42 145.4 3.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31502.1 - 2.8e-13 50.2 0.4 4.3e-13 49.6 0.3 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31502.1 - 3.8e-06 26.6 0.5 8.1e-06 25.5 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_8 PF06259.12 EON31502.1 - 0.01 15.5 0.2 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase DEAD PF00270.29 EON31502.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase ApbA PF02558.16 EON31502.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 EON31502.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MLTR_LBD PF17765.1 EON31503.1 - 1.9e-41 142.0 4.0 1.9e-41 142.0 4.0 1.5 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 EON31503.1 - 1.7e-09 37.9 0.3 3.6e-08 33.6 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Abhydrolase_1 PF00561.20 EON31504.1 - 1.9e-27 96.5 0.2 2.6e-27 96.1 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON31504.1 - 7.9e-21 74.4 0.1 7.5e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON31504.1 - 9.8e-19 68.8 3.8 1.2e-18 68.6 3.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EON31504.1 - 4e-08 33.0 0.1 3.8e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EON31504.1 - 0.0016 18.3 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 EON31504.1 - 0.0019 18.1 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase DLH PF01738.18 EON31504.1 - 0.0025 17.4 0.2 0.013 15.1 0.1 2.0 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EON31504.1 - 0.0078 15.8 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 EON31504.1 - 0.0089 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 EON31504.1 - 0.022 13.4 0.0 0.06 12.0 0.0 1.6 2 0 0 2 2 2 0 Ndr family UPF0227 PF05728.12 EON31504.1 - 0.068 13.1 0.0 10 6.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 EON31504.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) bacHORMA_1 PF18138.1 EON31504.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial HORMA domain family 1 Abhydrolase_6 PF12697.7 EON31505.1 - 2.2e-11 44.8 1.9 2.8e-11 44.5 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31505.1 - 9.2e-09 34.9 0.0 1.3e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON31505.1 - 1.2e-05 25.1 0.0 0.0038 16.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON31505.1 - 0.0019 17.7 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EON31505.1 - 0.0025 17.6 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family BAAT_C PF08840.11 EON31505.1 - 0.05 13.5 0.0 0.41 10.5 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 EON31505.1 - 0.058 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 EON31505.1 - 0.071 12.7 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Malate_DH PF12434.8 EON31505.1 - 0.086 12.9 0.0 0.33 11.0 0.0 2.0 1 0 0 1 1 1 0 Malate dehydrogenase enzyme COesterase PF00135.28 EON31506.1 - 1.1e-65 222.5 0.0 8.8e-62 209.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EON31506.1 - 2e-13 50.7 0.7 4.9e-13 49.4 0.7 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON31506.1 - 0.0047 15.8 0.0 0.58 9.0 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Esterase PF00756.20 EON31506.1 - 0.19 11.3 0.2 0.33 10.6 0.1 1.5 2 0 0 2 2 2 0 Putative esterase Peptidase_S15 PF02129.18 EON31507.1 - 3.9e-45 154.5 0.1 3.7e-39 135.0 0.3 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EON31507.1 - 2.1e-23 83.4 0.0 7.4e-23 81.7 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 EON31507.1 - 0.0031 16.8 0.0 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON31507.1 - 0.038 13.5 0.1 0.27 10.7 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family IMS PF00817.20 EON31508.1 - 1.4e-44 151.7 0.0 4.1e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EON31508.1 - 5.8e-18 65.7 2.1 1.1e-17 64.7 1.4 1.8 1 1 1 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EON31508.1 - 7.6e-09 35.4 0.0 2.4e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 EON31508.1 - 0.019 14.8 0.1 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EON31508.1 - 0.11 13.1 0.1 0.4 11.3 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain CitMHS PF03600.16 EON31509.1 - 2.4e-47 161.6 44.3 2.4e-47 161.6 44.3 2.4 2 1 0 2 2 2 1 Citrate transporter Na_H_antiporter PF03553.14 EON31509.1 - 3.7e-09 36.2 19.9 3.7e-09 36.2 19.9 2.2 2 0 0 2 2 2 2 Na+/H+ antiporter family CPP1-like PF11833.8 EON31509.1 - 0.039 13.6 0.5 0.039 13.6 0.5 3.6 4 0 0 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like sCache_3_2 PF17203.4 EON31510.1 - 7.8e-23 81.1 3.7 2.4e-22 79.6 2.5 2.4 2 0 0 2 2 2 1 Single cache domain 3 HATPase_c PF02518.26 EON31510.1 - 2.5e-16 60.2 0.1 5.5e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_a PF14689.6 EON31510.1 - 1.1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain PAS_4 PF08448.10 EON31510.1 - 2.9e-05 24.3 1.5 0.00029 21.0 0.6 2.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EON31510.1 - 0.0017 18.4 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 EON31510.1 - 0.0021 17.9 0.3 0.004 17.0 0.3 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 EON31510.1 - 0.0033 17.4 0.0 0.0095 15.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 EON31510.1 - 0.004 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EON31510.1 - 0.0073 16.3 0.3 0.026 14.5 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain dCache_3 PF14827.6 EON31510.1 - 0.0089 15.7 3.6 0.02 14.6 0.1 2.8 3 1 0 4 4 4 1 Double sensory domain of two-component sensor kinase PAS_7 PF12860.7 EON31510.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold Response_reg PF00072.24 EON31511.1 - 4.4e-14 52.6 0.0 6.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HTH_20 PF12840.7 EON31511.1 - 0.00034 20.6 0.2 0.00098 19.1 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EON31511.1 - 0.00085 19.2 0.4 0.0026 17.6 0.1 1.9 2 0 0 2 2 2 1 MarR family DprA_WH PF17782.1 EON31511.1 - 0.0012 19.0 0.2 0.0035 17.4 0.2 1.8 1 0 0 1 1 1 1 DprA winged helix domain HTH_IclR PF09339.10 EON31511.1 - 0.0013 18.5 0.1 0.0032 17.2 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 EON31511.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EON31511.1 - 0.041 13.5 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF977 PF06163.11 EON31511.1 - 0.067 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) PALP PF00291.25 EON31512.1 - 4.2e-41 141.3 2.1 5.3e-41 141.0 2.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_Gly3P_dh_N PF01210.23 EON31512.1 - 0.038 14.0 0.2 0.082 12.9 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus P33MONOX PF15302.6 EON31512.1 - 0.13 12.0 0.3 0.47 10.1 0.0 1.8 1 1 1 2 2 2 0 P33 mono-oxygenase DUF1641 PF07849.11 EON31512.1 - 0.14 12.0 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) DUF429 PF04250.13 EON31513.1 - 4e-28 98.7 11.1 4.6e-28 98.4 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF429) Acetyltransf_1 PF00583.25 EON31514.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON31514.1 - 1.9e-05 25.0 0.0 2.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON31514.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON31514.1 - 0.0022 18.1 0.0 0.0041 17.2 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EON31514.1 - 0.0058 16.6 0.0 0.1 12.6 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TetR_N PF00440.23 EON31515.1 - 2.8e-14 52.6 0.5 2.8e-14 52.6 0.5 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TRM PF02005.16 EON31515.1 - 0.1 11.7 0.1 0.13 11.4 0.1 1.3 1 1 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MerR_1 PF13411.6 EON31516.1 - 1.2e-16 60.6 0.0 1.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EON31516.1 - 2.8e-13 49.4 0.2 7.3e-13 48.1 0.1 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EON31516.1 - 1.7e-07 31.6 4.1 7.5e-07 29.6 4.1 2.0 1 1 0 1 1 1 1 MerR, DNA binding Rubella_E2 PF05749.11 EON31516.1 - 0.0041 16.6 0.0 0.0049 16.4 0.0 1.0 1 0 0 1 1 1 1 Rubella membrane glycoprotein E2 WIYLD PF10440.9 EON31516.1 - 0.054 13.3 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Trns_repr_metal PF02583.17 EON31517.1 - 5.4e-24 84.4 0.3 6.3e-24 84.1 0.3 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor ACT PF01842.25 EON31517.1 - 0.088 12.6 0.4 0.62 9.9 0.1 2.4 3 0 0 3 3 3 0 ACT domain MMPL PF03176.15 EON31518.1 - 2.8e-71 240.2 29.8 6.7e-49 166.6 10.0 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 EON31518.1 - 0.00075 19.4 6.1 0.00075 19.4 6.1 3.1 3 1 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EON31518.1 - 0.004 15.3 2.7 0.004 15.3 2.7 2.1 2 0 0 2 2 2 1 Patched family DUF87 PF01935.17 EON31521.1 - 2.7e-08 34.2 0.0 5.7e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain DUF853 PF05872.12 EON31521.1 - 4e-08 32.3 0.0 0.0041 15.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 EON31521.1 - 4.1e-06 26.3 0.0 0.003 16.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 EON31521.1 - 9.8e-05 22.7 0.0 0.39 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zot PF05707.12 EON31521.1 - 0.00022 20.9 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.29 EON31521.1 - 0.00092 19.6 0.0 0.021 15.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EON31521.1 - 0.0062 15.5 0.0 0.096 11.6 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 EON31521.1 - 0.09 12.5 0.0 0.64 9.8 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EON31521.1 - 0.1 12.3 0.2 2 8.1 0.0 2.7 2 1 0 3 3 3 0 AAA domain ResIII PF04851.15 EON31521.1 - 0.24 11.4 0.0 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EON31521.1 - 0.88 9.9 6.2 15 5.9 6.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain Acetyltransf_1 PF00583.25 EON31522.1 - 1.8e-11 44.3 0.0 2.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON31522.1 - 2.8e-07 30.9 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON31522.1 - 1.6e-06 28.1 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON31522.1 - 0.0059 16.6 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Penicil_amidase PF01804.18 EON31522.1 - 0.028 13.4 0.0 0.032 13.2 0.0 1.0 1 0 0 1 1 1 0 Penicillin amidase AurF PF11583.8 EON31523.1 - 5.7e-60 203.0 0.4 6.5e-60 202.8 0.4 1.0 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF PDH PF02153.17 EON31524.1 - 9.5e-20 70.7 0.0 1.7e-19 69.8 0.0 1.4 1 1 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 EON31524.1 - 0.08 12.6 0.1 3.3 7.3 0.1 2.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EON31524.1 - 0.1 13.2 0.5 1.2 9.7 0.5 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Chorismate_bind PF00425.18 EON31525.1 - 3.9e-91 305.2 0.0 7.1e-91 304.3 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EON31525.1 - 8.2e-41 139.9 0.0 1.4e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EON31525.1 - 1.5e-13 51.2 0.0 1.1e-12 48.4 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EON31525.1 - 3e-09 37.0 0.1 7.7e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 CM_2 PF01817.21 EON31526.1 - 1.5e-11 44.5 0.1 2e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Chorismate mutase type II NDUF_B4 PF07225.12 EON31526.1 - 0.038 13.9 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) CorA PF01544.18 EON31526.1 - 0.15 11.3 0.2 0.17 11.2 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Resolvase PF00239.21 EON31528.1 - 3.4e-19 69.4 0.0 9.7e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Resolvase, N terminal domain HTH_7 PF02796.15 EON31528.1 - 9.9e-11 41.5 0.1 1.7e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 EON31528.1 - 2.4e-07 30.4 0.3 9.6e-07 28.5 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON31528.1 - 1.5e-06 27.9 0.2 3.8e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_22 PF13309.6 EON31528.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_11 PF08279.12 EON31528.1 - 0.00015 21.6 0.0 0.00053 19.9 0.0 1.9 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 EON31528.1 - 0.00016 21.7 0.0 0.00016 21.7 0.0 3.4 3 2 1 4 4 3 1 Winged helix-turn helix TetR_N PF00440.23 EON31528.1 - 0.00028 20.6 0.0 0.0008 19.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_32 PF13565.6 EON31528.1 - 0.00041 20.9 1.3 0.0011 19.5 0.9 2.0 2 1 0 2 2 1 1 Homeodomain-like domain HTH_28 PF13518.6 EON31528.1 - 0.00043 20.4 0.3 0.0014 18.7 0.3 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 EON31528.1 - 0.00064 19.5 0.3 0.0025 17.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_20 PF12840.7 EON31528.1 - 0.0026 17.8 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 EON31528.1 - 0.0099 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 ECF sigma factor HTH_17 PF12728.7 EON31528.1 - 0.023 14.9 0.1 0.099 12.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 EON31528.1 - 0.037 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain HTH_IclR PF09339.10 EON31528.1 - 0.04 13.7 0.3 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 EON31528.1 - 0.071 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_Tnp_1 PF01527.20 EON31528.1 - 0.084 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Transposase Phage_AlpA PF05930.12 EON31528.1 - 0.088 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_26 PF13443.6 EON31528.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Mga PF05043.13 EON31528.1 - 0.13 12.9 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_6 PF01418.17 EON31528.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family CENP-B_N PF04218.13 EON31528.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_31 PF13560.6 EON31528.1 - 2.1 8.8 8.4 0.23 11.8 2.0 2.8 3 2 0 3 3 3 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 EON31529.1 - 1.1e-14 54.7 0.2 2.2e-08 34.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31529.1 - 2.6e-11 44.6 8.0 3.4e-11 44.2 8.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31529.1 - 0.0067 15.7 0.1 0.017 14.4 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON31529.1 - 0.012 15.1 0.1 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1057 PF06342.12 EON31529.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 EON31529.1 - 0.16 12.1 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DNA_binding_1 PF01035.20 EON31530.1 - 1.2e-22 79.9 0.0 1.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_15 PF12324.8 EON31530.1 - 0.006 16.5 0.3 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase F420H2_quin_red PF04075.14 EON31531.1 - 1.1e-46 158.1 0.5 1.3e-46 158.0 0.5 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase MaoC_dehydrat_N PF13452.6 EON31533.1 - 7.2e-34 116.8 0.3 4.3e-28 98.1 0.4 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 EON31533.1 - 4.1e-24 84.5 0.1 4.7e-17 61.7 0.0 3.0 2 1 1 3 3 3 2 MaoC like domain Antigen_Bd37 PF11641.8 EON31533.1 - 0.082 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein PGM1_C PF18105.1 EON31533.1 - 0.096 12.2 0.6 0.3 10.6 0.1 2.2 2 0 0 2 2 2 0 PGM1 C-terminal domain DUF2236 PF09995.9 EON31534.1 - 1.9e-20 74.1 9.7 4e-20 73.0 9.7 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lactamase_B PF00753.27 EON31535.1 - 4.8e-08 33.3 0.8 6.9e-08 32.7 0.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2849 PF11011.8 EON31535.1 - 0.14 12.8 1.6 22 5.8 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) TPP_enzyme_N PF02776.18 EON31536.1 - 2.1e-43 147.9 1.1 7.7e-41 139.6 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON31536.1 - 1.5e-39 135.2 0.2 6.1e-39 133.3 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON31536.1 - 1.8e-33 115.2 0.0 4e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EON31536.1 - 0.0032 17.3 0.1 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg L27 PF02828.16 EON31536.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 L27 domain Bac_luciferase PF00296.20 EON31537.1 - 9.4e-28 97.5 0.7 1.7e-27 96.7 0.7 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase GyrI-like PF06445.15 EON31538.1 - 5.8e-20 72.2 0.0 1e-19 71.4 0.0 1.3 1 1 0 1 1 1 1 GyrI-like small molecule binding domain HNH_2 PF13391.6 EON31538.1 - 0.0014 18.7 0.1 1.1 9.4 0.1 2.3 2 0 0 2 2 2 2 HNH endonuclease ABC2_membrane PF01061.24 EON31539.1 - 4.7e-21 75.2 15.5 6.8e-21 74.7 15.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON31539.1 - 1.6e-11 44.0 12.1 1.6e-11 44.0 12.1 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON31539.1 - 1.8 7.7 21.4 4.7 6.4 21.4 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 EON31540.1 - 4.9e-23 82.2 0.0 1.1e-22 81.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EON31540.1 - 2.7e-13 50.4 1.1 2e-08 34.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EON31540.1 - 2.8e-05 24.8 0.0 4.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) KdpD PF02702.17 EON31540.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_25 PF13481.6 EON31540.1 - 0.00068 19.3 2.8 0.055 13.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EON31540.1 - 0.0012 18.6 0.2 0.0026 17.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON31540.1 - 0.0035 17.9 0.2 0.0067 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EON31540.1 - 0.005 16.6 0.0 3.1 7.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EON31540.1 - 0.0056 16.2 0.0 0.16 11.4 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON31540.1 - 0.0057 17.0 0.2 0.012 16.0 0.1 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EON31540.1 - 0.031 14.0 0.2 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EON31540.1 - 0.034 13.8 0.5 0.062 12.9 0.5 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain HTH_11 PF08279.12 EON31540.1 - 0.044 13.7 0.1 15 5.7 0.0 2.6 2 0 0 2 2 2 0 HTH domain Putative_PNPOx PF01243.20 EON31541.1 - 4.9e-15 55.5 0.0 7.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON31541.1 - 6.8e-09 35.8 0.1 8.6e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EON31541.1 - 0.0052 16.4 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Beta-lactamase PF00144.24 EON31542.1 - 1.8e-59 201.6 0.9 2.5e-59 201.2 0.9 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EON31542.1 - 0.044 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PS_pyruv_trans PF04230.13 EON31543.1 - 8.4e-13 48.9 0.0 4.3e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase FAD_binding_3 PF01494.19 EON31544.1 - 2e-81 274.0 0.4 3.3e-81 273.2 0.4 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON31544.1 - 8.6e-06 25.2 0.1 3.8e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON31544.1 - 8.6e-06 26.2 0.0 0.061 13.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON31544.1 - 0.00012 21.0 0.2 0.071 11.8 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EON31544.1 - 0.00023 20.9 0.1 0.009 15.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON31544.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EON31544.1 - 0.0013 18.0 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON31544.1 - 0.0018 18.5 0.0 0.0052 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EON31544.1 - 0.003 17.0 0.1 0.014 14.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EON31544.1 - 0.0032 16.6 0.0 0.0065 15.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EON31544.1 - 0.0048 16.2 0.3 0.013 14.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NYN_YacP PF05991.11 EON31545.1 - 0.00029 20.8 0.1 0.0015 18.5 0.1 1.8 1 1 0 1 1 1 1 YacP-like NYN domain PIN_9 PF18477.1 EON31545.1 - 0.0018 18.5 0.1 0.0029 17.9 0.1 1.3 1 0 0 1 1 1 1 PIN like domain DUF188 PF02639.14 EON31545.1 - 0.0076 15.9 0.2 0.012 15.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 Fcf1 PF04900.12 EON31545.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Fcf1 FAD_binding_4 PF01565.23 EON31546.1 - 1.8e-25 89.3 1.5 3.1e-25 88.5 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EON31546.1 - 0.00056 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like AAA_16 PF13191.6 EON31547.1 - 1.1e-24 87.8 4.0 1.3e-24 87.5 0.1 3.1 4 0 0 4 4 3 1 AAA ATPase domain BTAD PF03704.17 EON31547.1 - 1.6e-22 80.5 6.3 1.6e-22 80.5 6.3 3.1 3 1 1 4 4 4 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 EON31547.1 - 1.2e-09 38.1 0.0 3.3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_19 PF14559.6 EON31547.1 - 0.00012 22.5 12.2 0.25 11.9 0.1 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat NACHT PF05729.12 EON31547.1 - 0.0054 16.7 0.1 0.04 13.8 0.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EON31547.1 - 0.0067 16.7 0.0 0.038 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON31547.1 - 0.014 15.1 0.9 0.063 13.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 EON31547.1 - 0.031 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) TPR_2 PF07719.17 EON31547.1 - 0.077 13.1 1.7 1.2e+02 3.2 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat MT0933_antitox PF14013.6 EON31547.1 - 0.16 12.3 0.1 0.47 10.8 0.1 1.8 1 0 0 1 1 1 0 MT0933-like antitoxin protein TPR_12 PF13424.6 EON31547.1 - 1.6 9.0 16.4 11 6.5 0.5 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EON31547.1 - 1.9 8.5 5.2 15 5.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyoxalase_6 PF18029.1 EON31548.1 - 8.3e-26 90.9 0.3 9.5e-26 90.7 0.3 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EON31548.1 - 0.00048 20.3 0.0 0.00059 20.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UDG PF03167.19 EON31549.1 - 2.7e-22 79.4 0.0 3.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF503 PF04456.12 EON31550.1 - 2.2e-30 104.3 0.1 2.6e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF503) PPK2 PF03976.14 EON31551.1 - 1.2e-109 365.2 0.3 1.4e-109 365.0 0.3 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) CutA1 PF03091.15 EON31551.1 - 0.056 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Ldh_1_C PF02866.18 EON31552.1 - 2e-30 105.9 0.0 3.7e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EON31552.1 - 6.1e-27 94.4 0.1 9.2e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF3489 PF11994.8 EON31552.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) META PF03724.16 EON31553.1 - 2.8e-16 59.4 0.0 3.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 META domain TauE PF01925.19 EON31555.1 - 0.0038 16.9 2.5 0.0047 16.6 0.1 1.9 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE SecA_DEAD PF07517.14 EON31556.1 - 1.1e-79 267.7 0.0 1.6e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 EON31556.1 - 2.3e-20 73.3 0.1 6.9e-20 71.8 0.1 1.8 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SecA_SW PF07516.13 EON31556.1 - 1.1e-18 68.0 0.0 2.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 SecA Wing and Scaffold domain DEAD PF00270.29 EON31556.1 - 2.6e-05 24.1 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON31556.1 - 0.0076 16.6 0.3 0.037 14.4 0.3 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CDP-OH_P_transf PF01066.21 EON31557.1 - 3.6e-13 50.1 0.3 3.6e-13 50.1 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF5357 PF17310.2 EON31557.1 - 0.56 8.7 4.8 0.87 8.1 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) GCV_H PF01597.19 EON31558.1 - 6.8e-38 129.3 0.0 7.5e-38 129.2 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EON31558.1 - 0.005 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF4916 PF16262.5 EON31558.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4916) RnfC_N PF13375.6 EON31558.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain FHA PF00498.26 EON31559.1 - 5.1e-19 68.4 0.1 7.2e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EON31559.1 - 5.7e-19 68.2 0.0 1.2e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain MerR PF00376.23 EON31560.1 - 1.1e-11 44.3 0.1 2.9e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 MerR family regulatory protein MerR_1 PF13411.6 EON31560.1 - 1e-08 35.1 0.0 2.9e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR_2 PF13591.6 EON31560.1 - 0.00022 21.0 0.0 0.087 12.7 0.0 2.4 2 0 0 2 2 2 2 MerR HTH family regulatory protein DNase-RNase PF02577.14 EON31561.1 - 3e-44 149.8 0.0 3.6e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease MerR_1 PF13411.6 EON31562.1 - 3.3e-14 52.7 0.0 5.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_28 PF13518.6 EON31562.1 - 0.021 14.9 0.4 2.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 EON31562.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 MerR family regulatory protein GDC-P PF02347.16 EON31563.1 - 7.6e-187 621.4 0.1 1.7e-175 584.0 0.0 2.6 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EON31563.1 - 4.3e-06 25.9 0.4 0.00016 20.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 EON31563.1 - 0.00085 18.7 0.2 0.011 15.0 0.0 2.3 2 0 0 2 2 2 1 Beta-eliminating lyase Neisseria_PilC PF05567.11 EON31564.1 - 0.07 12.1 0.4 0.12 11.3 0.4 1.3 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Malate_synthase PF01274.22 EON31565.1 - 3.4e-175 583.3 0.0 3.9e-175 583.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF21 PF01595.20 EON31567.1 - 1.4e-40 138.9 2.9 1.8e-40 138.5 2.9 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EON31567.1 - 5.8e-11 42.7 0.5 3.1e-06 27.5 0.4 2.6 2 0 0 2 2 2 2 CBS domain DUF21 PF01595.20 EON31568.1 - 2.9e-34 118.3 2.9 4.1e-34 117.8 2.9 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EON31568.1 - 1.3e-18 66.8 0.0 2.6e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 EON31568.1 - 3e-09 37.2 3.7 0.0007 20.0 0.5 2.5 2 0 0 2 2 2 2 CBS domain DUF4229 PF14012.6 EON31568.1 - 1.1 9.4 6.0 1 9.5 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Colicin_V PF02674.16 EON31568.1 - 9.1 6.2 8.3 0.2 11.6 0.7 2.0 2 1 0 2 2 2 0 Colicin V production protein IMPDH PF00478.25 EON31569.1 - 5.1e-98 328.3 1.9 5.9e-98 328.1 1.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EON31569.1 - 6.4e-10 39.3 3.0 4.3e-05 23.9 0.4 2.6 2 0 0 2 2 2 2 CBS domain His_biosynth PF00977.21 EON31569.1 - 4.8e-05 22.9 0.7 0.0077 15.7 0.0 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 EON31569.1 - 6.4e-05 22.5 18.2 0.00027 20.4 0.6 3.2 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 EON31569.1 - 0.0013 17.9 12.1 0.007 15.4 11.7 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EON31569.1 - 0.059 12.5 4.6 0.096 11.8 4.6 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EON31569.1 - 0.073 12.3 4.0 0.41 9.8 0.4 2.4 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase 6PGD PF00393.19 EON31570.1 - 1.4e-124 415.2 0.0 1.8e-124 414.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EON31570.1 - 4.4e-49 166.7 0.2 7.9e-49 165.9 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EON31570.1 - 0.00057 19.8 0.2 0.0012 18.8 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EON31570.1 - 0.00067 19.3 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EON31570.1 - 0.0009 19.8 1.6 0.0015 19.1 0.2 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EON31570.1 - 0.0087 16.1 0.1 0.018 15.1 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EON31570.1 - 0.033 13.5 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M48 PF01435.18 EON31571.1 - 6e-13 49.0 0.2 1.6e-12 47.6 0.2 1.8 1 1 1 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EON31571.1 - 4.6e-06 26.0 0.2 7.4e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 BlaR1 peptidase M56 Penicillinase_R PF03965.16 EON31572.1 - 3.6e-27 95.0 0.0 4.1e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 EON31572.1 - 2.2e-05 24.3 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 EON31572.1 - 0.0078 16.4 0.8 0.8 10.0 0.1 2.4 2 1 0 2 2 2 1 PaaX-like protein DUF4364 PF14277.6 EON31572.1 - 0.066 13.0 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) TBPIP PF07106.13 EON31572.1 - 0.076 13.0 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain GntR PF00392.21 EON31572.1 - 2 8.1 6.8 2.7 7.7 0.2 3.0 2 1 1 3 3 3 0 Bacterial regulatory proteins, gntR family 4HBT PF03061.22 EON31573.1 - 2.9e-14 53.2 1.1 4.6e-14 52.5 0.4 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 EON31573.1 - 0.0041 17.4 0.2 0.005 17.1 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Urease_gamma PF00547.18 EON31574.1 - 4.2e-48 161.7 0.1 4.7e-48 161.6 0.1 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 EON31575.1 - 3.8e-39 132.6 0.0 4.4e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_1 PF01979.20 EON31576.1 - 1.2e-68 232.0 1.3 1.6e-68 231.5 1.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EON31576.1 - 1.2e-51 174.1 1.0 2.6e-51 173.0 1.0 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 EON31576.1 - 3.3e-10 40.0 6.6 6.3e-09 35.8 2.7 2.5 1 1 1 2 2 2 2 Amidohydrolase family Molybdopterin_N PF18364.1 EON31576.1 - 0.11 12.5 0.5 5.4 7.1 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain UreF PF01730.16 EON31577.1 - 1.4e-10 41.9 2.3 1.8e-10 41.5 2.3 1.2 1 0 0 1 1 1 1 UreF cobW PF02492.19 EON31578.1 - 9.8e-36 123.0 0.1 1.2e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EON31578.1 - 1e-06 28.0 2.3 1e-05 24.7 2.3 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EON31578.1 - 0.0025 18.4 0.0 0.0041 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON31578.1 - 0.0067 16.8 0.0 0.0094 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EON31578.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EON31578.1 - 0.012 16.1 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 EON31578.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 EON31578.1 - 0.024 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 EON31578.1 - 0.037 13.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EON31578.1 - 0.049 13.8 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 EON31578.1 - 0.069 12.1 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA PF00004.29 EON31578.1 - 0.088 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EON31578.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 EON31578.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EON31578.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 EON31578.1 - 0.18 11.3 1.2 4.7 6.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 EON31578.1 - 0.2 11.6 0.3 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.15 EON31578.1 - 0.24 11.4 0.0 0.62 10.0 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EON31578.1 - 0.25 11.8 0.0 0.41 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase UreD PF01774.17 EON31579.1 - 2.5e-19 70.1 1.4 3.1e-19 69.8 1.4 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Pyr_redox_2 PF07992.14 EON31580.1 - 3.2e-53 180.9 1.8 3.9e-53 180.6 1.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON31580.1 - 9e-12 45.4 1.3 1.7e-06 28.5 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON31580.1 - 3.3e-06 26.4 4.6 0.0019 17.3 0.2 3.6 4 1 1 5 5 5 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EON31580.1 - 1.3e-05 25.3 1.2 0.00016 21.8 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON31580.1 - 7e-05 22.6 3.1 0.036 13.7 0.1 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON31580.1 - 0.00011 21.5 0.7 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EON31580.1 - 0.00016 20.9 2.3 0.0002 20.6 0.1 2.1 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON31580.1 - 0.0016 17.2 5.4 0.0068 15.2 0.1 3.4 3 1 1 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 EON31580.1 - 0.0019 17.3 0.1 0.19 10.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EON31580.1 - 0.0032 16.8 0.1 0.74 9.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON31580.1 - 0.0033 16.7 0.5 0.16 11.1 0.1 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EON31580.1 - 0.0075 16.7 0.1 0.03 14.8 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 EON31580.1 - 0.01 15.5 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EON31580.1 - 0.023 14.7 1.8 4.2 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EON31580.1 - 0.052 12.9 1.2 0.21 10.9 0.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON31580.1 - 0.058 12.7 2.9 1.5 8.1 0.1 3.0 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Acetyltransf_3 PF13302.7 EON31581.1 - 6.7e-33 114.3 0.1 1.7e-32 112.9 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON31581.1 - 1.1e-05 25.7 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EON31581.1 - 0.00019 21.1 0.1 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON31581.1 - 0.035 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 4HBT_2 PF13279.6 EON31582.1 - 9.5e-16 58.4 0.0 1.2e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EON31582.1 - 9e-10 38.3 0.0 8.8e-05 21.9 0.0 2.0 1 1 0 2 2 2 2 Acyl-ACP thioesterase 4HBT PF03061.22 EON31582.1 - 1.9e-07 31.3 0.0 4.1e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily Exonuc_V_gamma PF04257.14 EON31583.1 - 4.3e-176 587.4 0.0 6.6e-176 586.8 0.0 1.2 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 EON31583.1 - 6.1e-43 146.9 0.0 2.4e-42 145.0 0.0 2.1 2 0 0 2 2 2 1 RecC C-terminal domain DUF4682 PF15733.5 EON31583.1 - 0.24 12.0 0.0 0.49 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) UvrD-helicase PF00580.21 EON31584.1 - 1.8e-48 165.7 0.0 1.1e-46 159.9 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EON31584.1 - 1.4e-22 80.6 0.0 5.7e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EON31584.1 - 3.4e-16 59.6 0.0 8.9e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EON31584.1 - 2.8e-08 33.4 4.6 0.002 17.9 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EON31584.1 - 4.3e-08 33.1 1.5 0.002 17.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain PDDEXK_1 PF12705.7 EON31584.1 - 1e-05 25.6 0.0 7.8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_11 PF13086.6 EON31584.1 - 0.00026 20.8 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EON31584.1 - 0.0011 18.8 0.4 10 5.8 0.0 4.0 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EON31584.1 - 0.021 14.3 0.1 4.9 6.6 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein KdpD PF02702.17 EON31584.1 - 0.025 14.1 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_30 PF13604.6 EON31585.1 - 1.3e-32 113.1 5.3 2.3e-32 112.3 0.7 3.1 1 1 2 3 3 3 1 AAA domain AAA_19 PF13245.6 EON31585.1 - 2.9e-25 89.3 0.0 1.2e-24 87.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EON31585.1 - 2.4e-15 56.1 0.1 7.3e-15 54.5 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EON31585.1 - 4.5e-09 36.4 0.6 3.9e-06 26.8 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EON31585.1 - 1.9e-07 31.1 0.1 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EON31585.1 - 2.3e-07 30.5 0.2 0.00014 21.4 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein Helicase_RecD PF05127.14 EON31585.1 - 3.6e-05 23.7 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 Helicase SH3_13 PF18335.1 EON31585.1 - 0.00044 20.0 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 EON31585.1 - 0.0012 19.2 0.3 0.014 15.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain PIF1 PF05970.14 EON31585.1 - 0.0043 16.3 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C PF13361.6 EON31585.1 - 0.014 14.8 0.1 0.027 13.9 0.1 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 EON31585.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.21 EON31585.1 - 0.046 13.2 0.4 0.11 11.9 0.2 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EON31585.1 - 0.067 12.8 0.8 0.22 11.2 0.1 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EON31585.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4699 PF15770.5 EON31585.1 - 0.18 11.5 3.5 0.29 10.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) zf-SCNM1 PF15803.5 EON31585.1 - 0.89 9.3 0.0 0.89 9.3 0.0 2.1 3 0 0 3 3 3 0 Zinc-finger of sodium channel modifier 1 AAA_16 PF13191.6 EON31585.1 - 1 9.7 4.5 3.7 7.9 2.5 3.0 1 1 1 2 2 2 0 AAA ATPase domain Glyoxalase_6 PF18029.1 EON31586.1 - 0.0062 17.3 0.7 0.23 12.2 0.1 2.7 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.25 EON31586.1 - 0.0085 16.3 0.1 3.7 7.7 0.0 2.7 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DHFR_2 PF06442.11 EON31586.1 - 0.072 12.9 0.0 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 R67 dihydrofolate reductase Glyoxalase_4 PF13669.6 EON31586.1 - 0.13 12.5 0.0 3.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DoxX PF07681.12 EON31588.1 - 0.0002 21.9 4.1 0.00042 20.9 2.6 1.9 1 1 1 2 2 2 1 DoxX DoxX_3 PF13781.6 EON31588.1 - 0.076 13.6 1.3 0.18 12.4 0.8 1.9 1 1 0 1 1 1 0 DoxX-like family DUF3995 PF13160.6 EON31588.1 - 0.11 12.9 4.7 0.28 11.5 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) ELM2 PF01448.24 EON31588.1 - 0.17 12.6 0.1 0.31 11.8 0.1 1.3 1 0 0 1 1 1 0 ELM2 domain MFS_1 PF07690.16 EON31589.1 - 1.2e-50 172.4 53.4 1.3e-49 169.1 47.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON31589.1 - 0.86 8.4 10.1 2.8 6.7 0.2 2.2 2 0 0 2 2 2 0 MFS_1 like family Ser_hydrolase PF06821.13 EON31590.1 - 0.00034 20.5 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase DUF3525 PF12039.8 EON31590.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) TetR_N PF00440.23 EON31591.1 - 4.3e-13 48.8 0.1 9e-13 47.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EON31591.1 - 0.037 14.3 5.2 0.068 13.5 0.0 2.4 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 EON31591.1 - 0.075 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 EON31591.1 - 0.084 12.7 0.1 0.41 10.5 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 EON31591.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Chlorophyllase2 PF12740.7 EON31592.1 - 4.8e-10 38.8 0.0 7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EON31592.1 - 4.1e-08 32.6 0.0 5.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 EON31592.1 - 3.7e-05 22.4 0.2 0.00056 18.5 0.0 2.3 3 0 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 EON31592.1 - 7.5e-05 22.1 1.9 0.00076 18.8 1.5 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON31592.1 - 0.00045 19.8 0.1 0.004 16.7 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Polyketide_cyc2 PF10604.9 EON31593.1 - 5.3e-08 33.2 0.9 1.1e-07 32.3 0.9 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON31593.1 - 7.3e-05 23.0 0.1 0.00012 22.3 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ANTAR PF03861.14 EON31594.1 - 2.8e-19 68.7 0.2 5.4e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 ANTAR domain GAF_2 PF13185.6 EON31594.1 - 2e-14 54.1 0.1 2.9e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EON31594.1 - 0.00017 22.3 0.0 0.0003 21.4 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EON31594.1 - 0.019 15.3 0.0 0.091 13.1 0.0 1.9 1 1 1 2 2 2 0 GAF domain Cutinase PF01083.22 EON31595.1 - 2.1e-36 125.6 0.0 2.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EON31595.1 - 0.00017 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 EON31595.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EON31595.1 - 0.077 13.6 2.8 0.075 13.6 2.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.14 EON31595.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase N6_N4_Mtase PF01555.18 EON31596.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA methylase p450 PF00067.22 EON31597.1 - 2.2e-15 56.4 0.0 4.5e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PRC PF05239.16 EON31598.1 - 1.6e-05 24.9 0.0 5.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 PRC-barrel domain PRC PF05239.16 EON31599.1 - 0.045 13.8 2.3 0.26 11.4 2.3 1.9 1 1 0 1 1 1 0 PRC-barrel domain DUF2171 PF09939.9 EON31599.1 - 0.086 13.1 0.8 1.8 8.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) Nramp PF01566.18 EON31600.1 - 1.2e-56 192.2 20.3 1.6e-56 191.8 20.3 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein GPHR_N PF12537.8 EON31600.1 - 0.9 9.7 6.5 3 8.0 0.7 3.3 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal TetR_N PF00440.23 EON31602.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Abhydrolase_1 PF00561.20 EON31603.1 - 9.1e-24 84.5 0.1 5.6e-19 68.8 0.3 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31603.1 - 3.3e-18 67.1 8.1 3.3e-18 67.1 8.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31603.1 - 4.9e-18 65.3 0.3 8.1e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EON31603.1 - 0.00088 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 EON31603.1 - 0.012 15.8 0.0 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Ser_hydrolase PF06821.13 EON31603.1 - 0.033 14.1 0.2 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_5 PF12695.7 EON31603.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EON31603.1 - 0.12 11.8 0.3 1.7 8.1 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF676 PF05057.14 EON31603.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Rieske PF00355.26 EON31604.1 - 4.2e-12 45.9 0.2 7.1e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DapB_N PF01113.20 EON31605.1 - 1.7e-05 24.9 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EON31606.1 - 9.3e-30 103.5 0.1 4.8e-29 101.2 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31606.1 - 1.9e-18 66.9 0.4 4.5e-18 65.7 0.2 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31606.1 - 6.3e-08 32.7 0.3 1.2e-07 31.8 0.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31606.1 - 0.0027 17.2 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON31606.1 - 0.0092 15.9 0.8 0.016 15.1 0.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox_3 PF13738.6 EON31606.1 - 0.083 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Smoa_sbd PF17885.1 EON31607.1 - 5.3e-11 42.6 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Styrene monooxygenase A putative substrate binding domain Pyr_redox_2 PF07992.14 EON31607.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON31607.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EON31607.1 - 0.0023 17.1 0.1 0.0066 15.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EON31607.1 - 0.003 16.9 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 EON31607.1 - 0.0039 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EON31607.1 - 0.011 15.9 0.1 0.03 14.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 EON31607.1 - 0.04 14.5 0.0 0.096 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EON31607.1 - 0.045 14.2 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EON31607.1 - 0.21 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein RibD_C PF01872.17 EON31608.1 - 7.8e-19 68.3 0.0 2.5e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain Acyl_transf_3 PF01757.22 EON31609.1 - 2.1e-17 63.2 32.0 4.9e-17 62.0 32.0 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF218 PF02698.17 EON31610.1 - 3e-23 82.3 0.0 3.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain WES_acyltransf PF03007.16 EON31611.1 - 2e-68 231.0 0.3 4.4e-68 229.9 0.1 1.6 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON31611.1 - 9.3e-33 113.2 0.0 4.3e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1298) Condensation PF00668.20 EON31611.1 - 0.0016 17.2 0.2 0.087 11.5 0.1 2.1 2 0 0 2 2 2 2 Condensation domain CCG PF02754.16 EON31612.1 - 1.2e-31 108.8 1.6 6.5e-15 55.1 0.1 2.7 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 EON31612.1 - 2.6e-13 50.2 2.8 1.1e-12 48.1 2.8 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EON31612.1 - 2.8e-08 33.8 14.9 3.6e-08 33.4 9.6 3.3 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EON31612.1 - 5.9e-08 33.2 2.7 0.0038 17.8 0.2 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EON31612.1 - 6.2e-07 29.5 12.9 6.5e-07 29.4 9.0 2.7 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EON31612.1 - 1.7e-06 27.8 10.5 0.001 19.0 1.5 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EON31612.1 - 2.1e-06 28.1 4.7 0.023 15.3 0.2 2.9 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EON31612.1 - 1.1e-05 25.0 12.9 0.014 15.2 5.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EON31612.1 - 8.6e-05 23.4 6.9 0.096 13.6 0.4 3.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 EON31612.1 - 0.0068 16.8 17.7 0.13 12.9 1.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_22 PF17179.4 EON31612.1 - 0.063 14.1 9.0 0.59 11.0 0.2 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 EON31612.1 - 0.14 12.3 11.1 0.34 11.1 1.0 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON31612.1 - 0.23 11.6 12.9 2.7 8.2 1.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EON31612.1 - 1.1 9.5 5.4 1.2 9.3 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EON31612.1 - 1.3 10.1 23.4 0.055 14.4 5.1 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 EON31612.1 - 2.9 8.7 14.9 4.9 8.0 0.3 4.5 3 1 0 3 3 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EON31612.1 - 6.9 7.3 12.2 28 5.3 2.5 3.5 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Aminotran_1_2 PF00155.21 EON31613.1 - 5.2e-49 167.3 0.0 5.9e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EON31613.1 - 4.6e-08 32.8 0.0 6.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EON31613.1 - 0.00084 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EON31613.1 - 0.013 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EON31613.1 - 0.077 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.25 EON31614.1 - 5.8e-50 169.5 0.2 8.4e-50 169.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31614.1 - 9.9e-39 133.3 0.7 1.4e-38 132.8 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_1 PF00561.20 EON31614.1 - 2.3e-20 73.4 0.1 4.3e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31614.1 - 3.2e-13 50.8 18.3 3.2e-13 50.8 18.3 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31614.1 - 3.1e-11 43.0 0.1 6.8e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 KR PF08659.10 EON31614.1 - 1e-06 28.8 0.4 1.8e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Palm_thioest PF02089.15 EON31614.1 - 0.0067 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Epimerase PF01370.21 EON31614.1 - 0.082 12.4 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metal_hydrol PF10118.9 EON31615.1 - 4.5e-72 242.8 1.1 5.2e-72 242.6 1.1 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase Ferritin_2 PF13668.6 EON31615.1 - 0.039 14.2 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Ferritin-like domain Fer2 PF00111.27 EON31616.1 - 1.1e-11 44.6 0.2 2.3e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 EON31616.1 - 5.9e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EON31616.1 - 0.00069 20.2 0.1 0.02 15.5 0.1 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON31616.1 - 0.01 16.0 0.0 0.98 9.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.16 EON31617.1 - 2.8e-48 164.7 55.8 2.8e-48 164.7 55.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily CwsA PF10814.8 EON31617.1 - 0.84 9.8 6.8 0.11 12.7 1.8 2.1 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA TetR_C_33 PF13305.6 EON31618.1 - 1.5e-18 67.5 2.4 1.5e-18 67.5 2.4 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON31618.1 - 9e-09 35.0 0.0 2.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family UDPG_MGDP_dh_N PF03721.14 EON31620.1 - 2.3e-55 187.1 0.0 5e-55 186.0 0.0 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EON31620.1 - 1.4e-31 108.6 0.0 3.1e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EON31620.1 - 3.6e-27 94.8 0.0 1.7e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EON31620.1 - 4.1e-05 23.8 0.2 0.1 12.7 0.0 3.1 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EON31620.1 - 0.00017 21.5 0.1 0.00078 19.4 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON31620.1 - 0.00031 21.3 0.6 0.53 10.9 0.1 2.9 3 0 0 3 3 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EON31620.1 - 0.00066 20.1 0.1 0.35 11.3 0.0 3.1 3 1 0 3 3 3 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EON31620.1 - 0.0026 17.2 0.1 0.87 8.9 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EON31620.1 - 0.0034 17.6 0.3 0.023 15.0 0.0 2.4 3 0 0 3 3 3 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EON31620.1 - 0.026 13.8 0.1 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EON31620.1 - 0.065 13.2 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EON31620.1 - 0.071 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 EON31620.1 - 0.39 11.0 1.7 28 5.0 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DCD PF06559.11 EON31621.1 - 3.7e-13 49.0 0.0 4.6e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) dUTPase PF00692.19 EON31621.1 - 1.2e-11 44.4 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase AA_permease PF00324.21 EON31623.1 - 7.2e-124 414.0 41.3 8.1e-124 413.8 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON31623.1 - 8e-38 130.4 44.9 9.8e-38 130.1 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease Polyketide_cyc2 PF10604.9 EON31624.1 - 0.00054 20.2 0.2 0.00066 20.0 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Putative_PNPOx PF01243.20 EON31625.1 - 1.3e-13 50.9 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON31625.1 - 7.2e-05 22.8 0.1 0.00011 22.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F420_oxidored PF03807.17 EON31626.1 - 6.2e-19 68.4 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EON31626.1 - 2.4e-09 37.6 0.0 3.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 EON31626.1 - 5.9e-06 26.2 0.1 9.6e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 EON31626.1 - 9.7e-06 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 EON31626.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EON31626.1 - 0.00067 20.5 0.0 0.0012 19.6 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 EON31626.1 - 0.0011 18.7 0.4 0.0047 16.6 0.4 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EON31626.1 - 0.0022 17.6 0.2 0.0056 16.3 0.1 1.7 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.24 EON31626.1 - 0.0023 18.3 0.0 0.0038 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EON31626.1 - 0.0053 16.8 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EON31626.1 - 0.017 15.0 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 EON31626.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EON31626.1 - 0.05 13.5 0.2 0.11 12.4 0.2 1.5 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EON31626.1 - 0.058 14.0 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EON31626.1 - 0.076 13.0 0.2 2.1 8.3 0.0 2.1 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EON31626.1 - 0.099 12.9 0.1 0.17 12.1 0.1 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 EON31626.1 - 0.13 11.5 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LysR_substrate PF03466.20 EON31627.1 - 3.6e-23 82.0 7.6 2.2e-22 79.5 7.6 1.9 1 1 0 1 1 1 1 LysR substrate binding domain FluMu_N PF17891.1 EON31628.1 - 0.036 13.8 0.5 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain TetR_C_6 PF13977.6 EON31629.1 - 4.9e-22 78.3 4.4 4.9e-22 78.3 4.4 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 EON31629.1 - 5.9e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON31629.1 - 4.3e-05 23.7 8.3 4.3e-05 23.7 8.3 2.5 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 EON31629.1 - 0.036 13.9 0.4 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Homeodomain-like domain TetR_C_28 PF17937.1 EON31629.1 - 1.4 9.4 8.3 1.7 9.1 4.9 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF418 PF04235.12 EON31630.1 - 2.1e-31 109.1 8.2 2.1e-31 109.1 8.2 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF418) DUF2530 PF10745.9 EON31630.1 - 0.012 15.8 1.4 0.012 15.8 1.4 5.6 4 2 2 6 6 6 0 Protein of unknown function (DUF2530) ABC2_membrane_2 PF12679.7 EON31630.1 - 5 6.3 11.6 0.13 11.5 4.9 1.8 2 1 0 2 2 2 0 ABC-2 family transporter protein Peptidase_S49_N PF08496.10 EON31631.1 - 0.0014 18.8 5.0 0.0018 18.4 5.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal LYRIC PF15686.5 EON31631.1 - 0.0015 18.2 1.3 0.0017 18.0 1.3 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family ERM PF00769.19 EON31631.1 - 0.0029 17.5 11.3 0.0035 17.2 11.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family SpoIIIAH PF12685.7 EON31631.1 - 0.0033 17.3 1.4 0.0041 17.0 1.4 1.3 1 1 0 1 1 1 1 SpoIIIAH-like protein Mem_trans PF03547.18 EON31631.1 - 0.0034 15.8 0.1 0.0041 15.6 0.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Neur_chan_memb PF02932.16 EON31631.1 - 0.0038 17.3 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ASFV_J13L PF05568.11 EON31631.1 - 0.0045 16.8 0.3 0.0061 16.3 0.3 1.3 1 0 0 1 1 1 1 African swine fever virus J13L protein V_ATPase_I PF01496.19 EON31631.1 - 0.0058 14.6 0.9 0.0072 14.3 0.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HemX PF04375.14 EON31631.1 - 0.0093 15.3 7.9 0.012 15.0 7.9 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4307 PF14155.6 EON31631.1 - 0.021 14.6 0.7 0.035 13.9 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF4330 PF14221.6 EON31631.1 - 0.026 14.8 0.3 0.034 14.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) tRNA_anti-like PF12869.7 EON31631.1 - 0.028 14.0 2.8 0.039 13.6 2.8 1.2 1 0 0 1 1 1 0 tRNA_anti-like ECSCR PF15820.5 EON31631.1 - 0.029 14.2 0.4 0.052 13.4 0.4 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF2561 PF10812.8 EON31631.1 - 0.035 14.1 9.5 0.036 14.1 8.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF1198 PF06711.11 EON31631.1 - 0.035 14.2 0.2 0.045 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Adeno_E3_CR2 PF02439.15 EON31631.1 - 0.039 13.7 1.6 0.058 13.2 1.6 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Selenoprotein_S PF06936.11 EON31631.1 - 0.045 13.6 5.1 0.055 13.3 5.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) MAP17 PF15807.5 EON31631.1 - 0.076 13.3 5.2 0.1 12.9 4.5 1.5 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4381 PF14316.6 EON31631.1 - 0.089 13.0 10.4 0.18 12.1 10.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Wzz PF02706.15 EON31631.1 - 0.089 13.1 0.2 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 Chain length determinant protein EphA2_TM PF14575.6 EON31631.1 - 0.12 13.3 6.7 0.23 12.3 6.7 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmE PF03100.15 EON31631.1 - 0.13 12.2 0.3 0.19 11.7 0.3 1.2 1 0 0 1 1 1 0 CcmE Shisa PF13908.6 EON31631.1 - 0.13 12.4 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2615 PF11027.8 EON31631.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.5 4 0 0 4 4 1 0 Protein of unknown function (DUF2615) Miga PF10265.9 EON31631.1 - 0.15 11.0 1.6 0.18 10.8 1.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF4446 PF14584.6 EON31631.1 - 0.16 12.0 3.6 0.25 11.3 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Tmemb_9 PF05434.11 EON31631.1 - 0.17 11.8 3.2 0.28 11.1 3.2 1.4 1 1 0 1 1 1 0 TMEM9 CLN3 PF02487.17 EON31631.1 - 0.17 10.9 0.3 0.21 10.6 0.3 1.0 1 0 0 1 1 1 0 CLN3 protein Borrelia_P83 PF05262.11 EON31631.1 - 0.2 10.1 11.2 0.24 9.8 11.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4834 PF16118.5 EON31631.1 - 0.2 12.6 7.0 1.1 10.3 7.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Baculo_11_kDa PF06143.11 EON31631.1 - 0.21 11.2 1.5 0.47 10.1 1.5 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4668 PF15701.5 EON31631.1 - 0.22 11.3 0.2 0.27 11.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) SID-1_RNA_chan PF13965.6 EON31631.1 - 0.22 9.9 0.3 0.25 9.7 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NicO PF03824.16 EON31631.1 - 0.23 10.8 0.2 0.3 10.4 0.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SCIMP PF15050.6 EON31631.1 - 0.26 11.7 2.9 0.41 11.1 2.8 1.5 1 1 0 1 1 1 0 SCIMP protein DUF929 PF06053.11 EON31631.1 - 0.34 10.2 0.4 0.44 9.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) IgaA PF07095.11 EON31631.1 - 0.34 8.8 2.3 0.39 8.6 2.3 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA CBP_BcsG PF11658.8 EON31631.1 - 0.46 8.8 1.5 0.59 8.5 1.5 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG BatD PF13584.6 EON31631.1 - 0.51 9.1 4.9 0.28 9.9 3.2 1.4 1 1 0 1 1 1 0 Oxygen tolerance TMEM154 PF15102.6 EON31631.1 - 1.7 8.6 4.8 1.8 8.5 4.0 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF2681 PF10883.8 EON31631.1 - 1.7 9.1 15.7 4.6e+02 1.3 15.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Herpes_glycop PF01528.16 EON31631.1 - 2.4 6.9 6.5 2.8 6.7 6.5 1.3 1 1 0 1 1 1 0 Herpesvirus glycoprotein M XRN_M PF17846.1 EON31631.1 - 2.5 7.0 4.5 3 6.7 4.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF5313 PF17240.2 EON31631.1 - 2.5 8.6 5.0 2.4 8.6 3.7 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5313) DUF3093 PF11292.8 EON31631.1 - 2.8 8.2 8.2 0.53 10.5 4.9 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3093) DUF3365 PF11845.8 EON31631.1 - 3.5 7.9 10.7 69 3.7 10.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) TMEM51 PF15345.6 EON31631.1 - 4.8 7.0 9.4 15 5.3 9.2 1.8 1 1 1 2 2 2 0 Transmembrane protein 51 AAA_13 PF13166.6 EON31631.1 - 8.4 4.9 9.1 11 4.6 9.1 1.0 1 0 0 1 1 1 0 AAA domain Ctr PF04145.15 EON31631.1 - 9.1 6.9 6.5 15 6.2 6.5 1.6 1 1 0 1 1 1 0 Ctr copper transporter family DUF948 PF06103.11 EON31631.1 - 9.2 6.6 7.4 41 4.5 7.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MMPL PF03176.15 EON31632.1 - 3.1e-93 312.4 35.9 8e-55 186.1 17.1 2.2 2 0 0 2 2 2 2 MMPL family DUF4179 PF13786.6 EON31632.1 - 0.78 10.3 0.0 0.78 10.3 0.0 5.3 5 2 0 5 5 5 0 Domain of unknown function (DUF4179) TetR_N PF00440.23 EON31633.1 - 3.6e-16 58.7 0.3 7.1e-16 57.7 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON31633.1 - 0.00022 21.4 0.0 0.00039 20.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 EON31633.1 - 0.0011 19.0 0.2 0.006 16.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON31633.1 - 0.0023 17.7 0.2 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain TetR_C_14 PF17754.1 EON31633.1 - 0.0028 17.6 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 MftR C-terminal domain HTH_29 PF13551.6 EON31633.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix LacI PF00356.21 EON31633.1 - 0.054 13.3 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TA_inhibitor PF17574.2 EON31633.1 - 0.07 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) PAP2 PF01569.21 EON31634.1 - 5.7e-16 58.5 0.1 1.3e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EON31634.1 - 5.6e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily NHase_alpha PF02979.16 EON31634.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Peripla_BP_6 PF13458.6 EON31636.1 - 8.4e-31 107.9 7.9 1.1e-30 107.5 7.9 1.0 1 0 0 1 1 1 1 Periplasmic binding protein BPD_transp_2 PF02653.16 EON31637.1 - 1.1e-40 139.5 87.2 4.8e-25 88.2 42.2 2.4 2 1 0 2 2 2 2 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EON31638.1 - 5.1e-23 82.1 0.0 6.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 EON31638.1 - 5.7e-11 42.1 0.3 1.3e-10 40.9 0.3 1.7 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 EON31638.1 - 3e-07 30.5 0.1 0.00073 19.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON31638.1 - 0.00013 21.6 0.5 0.00024 20.8 0.5 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON31638.1 - 0.00013 21.4 0.0 0.0012 18.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON31638.1 - 0.00046 20.7 0.2 0.00061 20.3 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON31638.1 - 0.031 14.6 0.0 0.59 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON31638.1 - 0.033 14.3 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON31638.1 - 0.048 14.0 0.4 0.078 13.4 0.4 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EON31638.1 - 0.05 13.3 4.0 0.12 12.1 4.0 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON31638.1 - 0.055 13.3 0.1 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 EON31638.1 - 0.062 13.0 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EON31638.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EON31638.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON31638.1 - 0.13 12.2 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EON31638.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EON31639.1 - 3.9e-23 82.5 0.0 5.4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31639.1 - 2.9e-08 33.9 2.7 3.2e-05 23.9 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON31639.1 - 1.3e-05 25.5 0.6 0.035 14.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EON31639.1 - 0.00044 19.7 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EON31639.1 - 0.015 15.0 0.9 0.091 12.5 0.9 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EON31639.1 - 0.025 15.0 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EON31639.1 - 0.032 13.8 2.4 0.17 11.4 2.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EON31639.1 - 0.045 14.1 0.0 0.083 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EON31639.1 - 0.07 12.5 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 EON31639.1 - 0.084 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EON31639.1 - 0.16 12.4 1.2 0.46 10.9 1.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EON31639.1 - 0.21 12.1 0.0 0.29 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain TetR_N PF00440.23 EON31640.1 - 7.5e-14 51.3 0.1 7.5e-14 51.3 0.1 2.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 EON31640.1 - 0.00019 22.1 0.5 0.00019 22.1 0.5 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DPRP PF04244.13 EON31641.1 - 3.3e-55 187.4 0.0 5.3e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein FAD_binding_7 PF03441.14 EON31641.1 - 2.9e-07 30.2 0.3 5.9e-07 29.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase MFS_1 PF07690.16 EON31643.1 - 4.8e-47 160.6 46.3 1.4e-46 159.1 44.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON31643.1 - 2.4e-09 36.6 3.6 2.4e-09 36.6 3.6 3.8 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EON31643.1 - 2.3e-06 26.3 9.6 2.3e-06 26.3 9.6 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EON31643.1 - 8.2e-06 25.0 1.0 0.00087 18.3 0.2 2.4 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM OATP PF03137.20 EON31643.1 - 1.5 7.1 6.7 1.1 7.4 0.1 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_transf_4 PF13439.6 EON31645.1 - 0.0037 17.3 0.1 0.0063 16.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON31645.1 - 0.026 15.0 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain SH3_3 PF08239.11 EON31645.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial SH3 domain YfhO PF09586.10 EON31646.1 - 1.5 7.0 3.1 2.2 6.4 3.1 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2254 PF10011.9 EON31646.1 - 3.2 6.5 8.9 2.7 6.7 7.3 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) SnoaL_4 PF13577.6 EON31648.1 - 2.7e-26 92.2 0.7 3.3e-26 91.9 0.7 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EON31648.1 - 0.00014 22.5 0.6 0.00019 22.0 0.6 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON31648.1 - 0.0035 17.7 0.7 0.0063 16.9 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EON31648.1 - 0.013 15.7 0.1 0.056 13.7 0.1 1.8 1 1 0 1 1 1 0 SnoaL-like domain GBP_PSP PF02425.15 EON31648.1 - 1.5 8.5 5.0 16 5.3 0.2 3.0 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Pribosyltran PF00156.27 EON31649.1 - 1e-18 67.4 0.8 1.3e-18 67.0 0.8 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EON31649.1 - 0.00051 19.6 0.0 0.00092 18.7 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EON31649.1 - 0.0045 16.5 0.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase Pribosyl_synth PF14572.6 EON31649.1 - 0.08 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain GerE PF00196.19 EON31650.1 - 4.9e-15 54.8 0.0 9.7e-15 53.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_19 PF14559.6 EON31650.1 - 4.7e-08 33.4 0.9 0.069 13.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Sigma70_r4_2 PF08281.12 EON31650.1 - 3.7e-07 29.7 0.2 1.6e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 AAA_22 PF13401.6 EON31650.1 - 3.1e-06 27.5 0.0 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain HTH_38 PF13936.6 EON31650.1 - 7.4e-05 22.4 0.0 0.00089 19.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON31650.1 - 0.00098 18.9 0.1 0.0042 16.8 0.1 2.1 1 0 0 1 1 1 1 Homeodomain-like domain NACHT PF05729.12 EON31650.1 - 0.0014 18.6 0.1 0.043 13.7 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EON31650.1 - 0.0026 18.0 4.5 0.011 16.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EON31650.1 - 0.0035 17.7 0.1 0.0035 17.7 0.1 4.5 4 3 2 6 6 4 1 AAA ATPase domain HTH_40 PF14493.6 EON31650.1 - 0.0046 17.4 0.0 0.022 15.2 0.0 2.1 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_20 PF12840.7 EON31650.1 - 0.0077 16.3 6.0 13 5.9 0.2 5.2 5 0 0 5 5 4 0 Helix-turn-helix domain TPR_6 PF13174.6 EON31650.1 - 0.011 16.4 0.9 18 6.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_5 PF07728.14 EON31650.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma70_ECF PF07638.11 EON31650.1 - 0.013 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 ECF sigma factor AAA PF00004.29 EON31650.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EON31650.1 - 0.031 14.2 0.1 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 EON31650.1 - 0.036 14.0 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EON31650.1 - 0.041 14.4 0.0 0.093 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON31650.1 - 0.058 13.6 0.2 0.25 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_14 PF13428.6 EON31650.1 - 0.067 14.0 19.8 0.5 11.3 1.7 6.1 3 1 2 5 5 5 0 Tetratricopeptide repeat RuvB_N PF05496.12 EON31650.1 - 0.098 12.4 0.5 0.55 10.0 0.0 2.5 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EON31650.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase LPD7 PF18821.1 EON31650.1 - 0.33 11.1 6.9 3.3 7.9 3.2 2.9 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 AAA_19 PF13245.6 EON31650.1 - 2.7 8.3 4.5 29 5.0 0.4 2.9 3 0 0 3 3 3 0 AAA domain ABC2_membrane_4 PF12730.7 EON31651.1 - 1.3e-07 31.8 2.1 1.3e-07 31.8 2.1 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON31651.1 - 0.036 13.4 26.0 0.0085 15.4 19.0 2.4 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF3742 PF12553.8 EON31651.1 - 3.3 7.8 8.1 7.7 6.7 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) ABC_tran PF00005.27 EON31652.1 - 1.6e-24 87.0 0.0 2.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31652.1 - 3.3e-12 46.8 0.1 6.2e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON31652.1 - 0.0055 17.2 0.0 0.0082 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON31652.1 - 0.031 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EON31652.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 EON31652.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.7 2 0 0 2 2 2 0 MukB N-terminal ThiG PF05690.14 EON31653.1 - 1.9e-98 328.7 2.8 2.2e-98 328.5 2.8 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 EON31653.1 - 0.00031 19.9 1.6 0.011 14.8 0.2 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.21 EON31653.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 EON31653.1 - 0.059 12.5 0.1 0.88 8.7 0.0 2.2 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 EON31653.1 - 0.14 11.3 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) ThiS PF02597.20 EON31654.1 - 1e-12 48.5 0.4 1.2e-12 48.3 0.4 1.0 1 0 0 1 1 1 1 ThiS family Lambda_tail_I PF06805.12 EON31654.1 - 4.3e-05 23.8 1.4 5.5e-05 23.4 0.9 1.4 1 1 0 1 1 1 1 Bacteriophage lambda tail assembly protein I TGS PF02824.21 EON31654.1 - 0.0014 18.6 0.4 0.0023 17.9 0.4 1.3 1 0 0 1 1 1 1 TGS domain Ub-Mut7C PF14451.6 EON31654.1 - 0.066 13.1 0.4 0.3 10.9 0.2 1.9 1 1 1 2 2 2 0 Mut7-C ubiquitin ThiS-like PF14453.6 EON31654.1 - 0.077 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 ThiS-like ubiquitin DAO PF01266.24 EON31655.1 - 8.6e-45 153.8 12.4 9.7e-45 153.7 12.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON31655.1 - 1.8e-05 24.1 2.2 3.2e-05 23.2 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON31655.1 - 6.4e-05 22.3 0.2 0.00021 20.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON31655.1 - 0.00027 21.1 0.9 0.00063 19.9 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF4232 PF14016.6 EON31655.1 - 0.0048 17.0 0.4 0.015 15.4 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) GIDA PF01134.22 EON31655.1 - 0.007 15.5 2.2 0.01 14.9 2.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EON31655.1 - 0.0072 15.1 0.2 0.012 14.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EON31655.1 - 0.0086 16.6 0.6 0.021 15.4 0.3 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EON31655.1 - 0.013 15.4 1.1 0.021 14.7 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EON31655.1 - 0.023 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON31655.1 - 0.026 13.8 0.9 0.045 13.1 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EON31655.1 - 0.23 10.8 3.3 0.37 10.1 3.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TMP-TENI PF02581.17 EON31656.1 - 1.8e-48 164.3 0.2 2.1e-48 164.1 0.2 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase LeuA_dimer PF08502.10 EON31657.1 - 0.00028 20.8 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain NUDIX PF00293.28 EON31658.1 - 1.9e-13 50.6 0.2 2.5e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EON31658.1 - 1.1e-05 25.4 0.1 1.6e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_M22 PF00814.25 EON31658.1 - 0.067 12.9 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family DUF4131 PF13567.6 EON31659.1 - 0.17 11.5 3.5 0.47 10.1 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SBP_bac_3 PF00497.20 EON31660.1 - 1.1e-45 155.8 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EON31660.1 - 0.023 14.9 0.2 0.081 13.1 0.1 1.8 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site PknG_TPR PF16918.5 EON31661.1 - 1e-114 382.9 1.6 1.3e-114 382.5 1.6 1.1 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat PknG_rubred PF16919.5 EON31661.1 - 1.8e-35 122.1 0.9 1.8e-35 122.1 0.9 2.2 2 0 0 2 2 2 1 Protein kinase G rubredoxin domain Pkinase PF00069.25 EON31661.1 - 4.8e-31 108.1 0.0 6.9e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON31661.1 - 4.4e-12 45.9 0.0 6.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_19 PF14559.6 EON31661.1 - 5.5e-06 26.8 5.1 0.093 13.3 0.2 4.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EON31661.1 - 0.00017 22.1 6.9 0.027 15.1 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EON31661.1 - 0.0075 15.9 1.0 2.5 7.7 0.0 3.0 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 EON31661.1 - 0.02 15.7 9.5 0.096 13.6 0.3 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EON31661.1 - 0.027 15.1 0.0 8.9 7.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DZR PF12773.7 EON31661.1 - 0.2 11.7 0.2 0.38 10.8 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon TetR_C_33 PF13305.6 EON31661.1 - 1.1 10.1 5.6 0.77 10.5 0.1 3.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_4 PF07721.14 EON31661.1 - 1.1 10.0 17.7 0.65 10.8 2.4 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat HscB_4_cys PF18256.1 EON31661.1 - 1.4 8.8 5.4 0.5 10.2 1.5 2.2 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif TPR_12 PF13424.6 EON31661.1 - 1.4 9.3 5.8 8.8 6.7 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-NADH-PPase PF09297.11 EON31661.1 - 2 8.2 4.8 4 7.2 0.5 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Asn_synthase PF00733.21 EON31663.1 - 2e-105 353.4 0.1 2.4e-105 353.1 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EON31663.1 - 3.1e-40 136.9 0.0 5.4e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EON31663.1 - 2.8e-36 124.6 0.0 4.9e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EON31663.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 EON31663.1 - 0.0043 16.6 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 EON31663.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD synthase COX2 PF00116.20 EON31664.1 - 9.4e-15 54.6 0.6 2.5e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 EON31664.1 - 0.0068 16.5 1.0 0.011 15.8 1.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Polysacc_synt_C PF14667.6 EON31664.1 - 0.03 14.4 0.6 0.053 13.6 0.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Oxidored_q3 PF00499.20 EON31664.1 - 0.043 13.5 0.4 0.067 12.9 0.4 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NDUF_B8 PF05821.11 EON31664.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cyt_c_ox_IV PF12270.8 EON31665.1 - 2.4e-48 163.6 7.1 2.7e-48 163.5 7.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF2721 PF11026.8 EON31665.1 - 5.4 6.9 9.8 1.7 8.5 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SLATT_1 PF18181.1 EON31665.1 - 7.5 6.5 10.9 0.29 11.1 1.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DAGK_cat PF00781.24 EON31666.1 - 2.4e-18 65.9 0.3 4.8e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAP2 PF01569.21 EON31666.1 - 5.8e-15 55.3 0.3 1.4e-14 54.0 0.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EON31666.1 - 1.2e-08 34.9 0.4 1.2e-08 34.9 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily NAD_kinase PF01513.21 EON31666.1 - 0.0012 18.1 0.2 0.0016 17.7 0.2 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Cytochrom_B_N_2 PF13631.6 EON31667.1 - 2.2e-62 210.0 9.9 2.2e-62 210.0 9.9 2.8 4 0 0 4 4 4 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 EON31667.1 - 1.5e-22 80.3 23.1 6.9e-22 78.2 15.2 3.2 2 1 0 2 2 2 1 Cytochrome b/b6/petB DUF4405 PF14358.6 EON31667.1 - 0.00014 22.3 8.0 0.00014 22.3 8.0 4.5 3 2 0 3 3 3 1 Domain of unknown function (DUF4405) DUF4079 PF13301.6 EON31667.1 - 0.35 11.0 8.5 3.4 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) DUF4131 PF13567.6 EON31667.1 - 5.2 6.7 11.2 5.7 6.6 1.5 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Rieske PF00355.26 EON31668.1 - 1.7e-10 40.7 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Phage_holin_3_6 PF07332.11 EON31668.1 - 0.1 12.6 4.1 0.38 10.8 0.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Cytochrome_CBB3 PF13442.6 EON31669.1 - 6e-21 74.5 0.0 1.8e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EON31669.1 - 1.3e-16 61.5 2.4 1.1e-05 26.5 0.1 3.8 2 2 1 3 3 3 3 Cytochrome c Cytochrom_C550 PF14495.6 EON31669.1 - 0.00015 21.5 0.1 0.47 10.1 0.0 2.7 2 1 0 2 2 2 2 Cytochrome c-550 domain CCP_MauG PF03150.14 EON31669.1 - 0.0084 16.8 0.0 2.4 8.8 0.0 2.2 2 0 0 2 2 2 2 Di-haem cytochrome c peroxidase Cytochrome_C7 PF14522.6 EON31669.1 - 0.018 15.1 0.0 8.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF1924 PF09086.11 EON31669.1 - 0.032 14.6 2.6 3.4 8.1 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1924) Cytochrom_C1 PF02167.15 EON31669.1 - 0.036 13.8 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Cytochrome C1 family MCR PF18509.1 EON31669.1 - 0.29 10.8 2.8 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Magnetochrome domain Trp_oprn_chp PF09534.10 EON31669.1 - 0.7 9.7 8.3 0.23 11.2 2.1 2.5 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3040 PF11239.8 EON31669.1 - 3.9 7.8 9.3 0.78 10.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) COX3 PF00510.18 EON31670.1 - 1.4e-26 93.9 12.8 1.7e-26 93.6 12.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III RraB PF06877.11 EON31671.1 - 0.028 15.1 0.0 0.036 14.8 0.0 1.2 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Glycos_transf_3 PF00591.21 EON31672.1 - 1.9e-83 279.9 3.5 2.7e-83 279.4 3.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EON31672.1 - 1.6e-15 56.7 0.5 1.6e-15 56.7 0.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain SAM_MT PF04445.13 EON31672.1 - 0.2 11.1 0.3 0.37 10.2 0.3 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase AsnC_trans_reg PF01037.21 EON31673.1 - 2.6e-17 62.6 0.1 2.9e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 EON31673.1 - 0.0015 18.6 1.7 0.0019 18.2 1.7 1.1 1 0 0 1 1 1 1 NapD protein RNase_T PF00929.24 EON31674.1 - 7.1e-38 130.7 0.0 1.2e-37 130.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EON31674.1 - 1.3e-08 35.0 0.0 5.2e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 3' exoribonuclease, RNase T-like GIY-YIG PF01541.24 EON31674.1 - 0.00037 20.7 0.0 0.00065 19.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain RNase_H_2 PF13482.6 EON31674.1 - 0.023 14.7 0.0 0.24 11.4 0.0 2.1 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 EON31674.1 - 0.1 12.3 0.1 2.5 7.8 0.0 2.7 3 0 0 3 3 3 0 3'-5' exonuclease UVR PF02151.19 EON31674.1 - 0.23 11.3 0.5 0.64 9.8 0.2 1.9 2 0 0 2 2 2 0 UvrB/uvrC motif NLPC_P60 PF00877.19 EON31675.1 - 6.1e-21 74.4 0.2 8.7e-21 73.9 0.2 1.2 1 0 0 1 1 1 1 NlpC/P60 family CHAP PF05257.16 EON31675.1 - 0.00038 21.0 0.2 0.00067 20.2 0.2 1.3 1 0 0 1 1 1 1 CHAP domain Peptidase_C92 PF05708.12 EON31675.1 - 0.00044 20.4 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Amidase_5 PF05382.13 EON31675.1 - 0.0011 18.8 4.1 0.0098 15.8 4.1 2.0 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase NLPC_P60 PF00877.19 EON31676.1 - 1.1e-22 80.1 0.3 8.5e-22 77.2 0.0 2.4 3 0 0 3 3 3 1 NlpC/P60 family Amidase_5 PF05382.13 EON31676.1 - 0.019 14.8 0.2 0.14 12.0 0.2 2.2 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase LRAT PF04970.13 EON31676.1 - 0.025 14.9 0.5 0.025 14.9 0.5 2.6 2 1 0 3 3 3 0 Lecithin retinol acyltransferase CHAP PF05257.16 EON31676.1 - 0.075 13.6 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 CHAP domain DUF4032 PF13224.6 EON31676.1 - 0.078 12.9 0.5 0.14 12.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) TPR_MLP1_2 PF07926.12 EON31676.1 - 1.1 9.3 12.8 1.2 9.2 3.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BSP PF04450.12 EON31677.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase of plants and bacteria DUF4157 PF13699.6 EON31677.1 - 0.08 13.2 1.7 0.11 12.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Glycos_transf_1 PF00534.20 EON31678.1 - 2.8e-42 144.2 0.0 4.7e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON31678.1 - 1.9e-30 106.0 0.1 4.7e-30 104.7 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON31678.1 - 1.4e-13 51.2 2.8 3.4e-13 49.9 2.8 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EON31678.1 - 1.8e-07 31.5 0.0 4.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 AMP-binding PF00501.28 EON31679.1 - 1.3e-91 307.3 0.1 1.8e-91 306.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Polyketide_cyc2 PF10604.9 EON31680.1 - 0.00093 19.5 3.9 0.0012 19.1 3.8 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EON31681.1 - 6.8e-13 49.1 1.0 7.9e-13 48.9 1.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON31681.1 - 6e-10 39.4 0.1 9e-10 38.9 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 EON31681.1 - 0.031 14.4 0.2 0.093 12.8 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2505) ArsA_ATPase PF02374.15 EON31682.1 - 1.2e-09 37.8 0.0 1.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase ArsA_HSP20 PF17886.1 EON31682.1 - 1.9e-09 37.0 0.0 7.4e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Acetyltransf_6 PF13480.7 EON31682.1 - 0.0046 17.1 2.2 0.012 15.7 2.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pox_P4B PF03292.14 EON31682.1 - 0.085 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein ROK PF00480.20 EON31684.1 - 1.8e-71 241.1 0.4 2e-71 240.9 0.4 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 EON31684.1 - 1.7e-06 27.3 4.6 6.8e-05 22.0 4.6 2.8 1 1 0 1 1 1 1 Glucokinase BcrAD_BadFG PF01869.20 EON31684.1 - 0.017 14.7 0.1 0.017 14.7 0.1 2.3 2 2 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 EON31684.1 - 0.04 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase FGGY_N PF00370.21 EON31684.1 - 0.053 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain RNA_pol_inhib PF16857.5 EON31684.1 - 0.1 12.4 0.3 0.31 10.9 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase inhibitor TCR PF03638.15 EON31684.1 - 0.35 11.2 2.2 0.5 10.7 2.2 1.2 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Acyltransferase PF01553.21 EON31685.1 - 1.5e-28 99.1 0.0 2.2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF374 PF04028.13 EON31685.1 - 0.043 13.4 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF374) GT87 PF09594.10 EON31686.1 - 3.4e-46 157.9 33.9 3.4e-46 157.9 33.9 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 87 NUDIX PF00293.28 EON31686.1 - 7.9e-16 58.3 0.6 1.2e-15 57.7 0.6 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EON31686.1 - 6.5e-07 29.3 0.1 1.5e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain DUF5051 PF16473.5 EON31687.1 - 2.4e-19 69.9 0.0 4.3e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DAHP_synth_2 PF01474.16 EON31688.1 - 1.4e-184 613.7 0.0 1.7e-184 613.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Pkinase PF00069.25 EON31689.1 - 4.2e-45 154.2 0.0 5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON31689.1 - 7.9e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON31689.1 - 1.5e-05 25.1 1.0 0.0092 15.9 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EON31689.1 - 0.0014 18.0 0.0 0.0063 15.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EON31689.1 - 0.058 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EON31689.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Rv2175c_C PF18367.1 EON31690.1 - 1.1e-21 76.6 0.1 1.9e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function HTH_17 PF12728.7 EON31690.1 - 0.00027 21.1 0.0 0.00048 20.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EON31690.1 - 0.0023 17.3 0.6 0.0023 17.3 0.6 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 EON31690.1 - 0.023 14.2 0.2 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 EON31690.1 - 0.06 13.2 0.5 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain polyprenyl_synt PF00348.17 EON31692.1 - 3.4e-50 170.5 0.0 4.9e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase MTHFR PF02219.17 EON31693.1 - 8.7e-82 274.7 0.0 1.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3153 PF11353.8 EON31694.1 - 0.00087 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) Acyl_transf_3 PF01757.22 EON31694.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase family NAD_binding_8 PF13450.6 EON31695.1 - 8.8e-12 45.1 0.2 8.8e-12 45.1 0.2 3.3 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON31695.1 - 9.5e-10 38.3 5.2 1.1e-07 31.5 0.6 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EON31695.1 - 1.4e-05 24.9 1.9 1.4e-05 24.9 1.9 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON31695.1 - 0.00027 19.8 0.4 0.00044 19.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EON31695.1 - 0.0004 19.9 0.5 0.0004 19.9 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON31695.1 - 0.00071 18.9 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON31695.1 - 0.0018 17.5 0.1 0.0036 16.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EON31695.1 - 0.0024 16.8 0.5 0.0043 16.0 0.5 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EON31695.1 - 0.0042 16.2 1.7 0.0042 16.2 1.7 2.4 3 1 1 4 4 4 1 FAD binding domain Pyr_redox PF00070.27 EON31695.1 - 0.0055 17.2 0.5 0.014 16.0 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON31695.1 - 0.0065 15.6 0.4 0.0065 15.6 0.4 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EON31695.1 - 0.007 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 EON31695.1 - 0.039 12.7 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 EON31695.1 - 0.14 11.4 0.3 0.3 10.3 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EON31695.1 - 0.22 11.0 0.0 0.49 9.9 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Acetyltransf_10 PF13673.7 EON31696.1 - 3.4e-07 30.3 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON31696.1 - 3.4e-07 30.6 0.0 5.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON31696.1 - 8.5e-06 26.0 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EON31696.1 - 2.5e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EON31696.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_holin_2_1 PF04971.12 EON31696.1 - 0.1 12.6 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S PanZ PF12568.8 EON31696.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ HEPN_SAV_6107 PF18726.1 EON31697.1 - 7.6e-26 90.5 0.1 1.3e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 SAV_6107-like HEPN DUF3040 PF11239.8 EON31698.1 - 1.1e-20 73.7 1.7 1.6e-20 73.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) HisKA_7TM PF16927.5 EON31698.1 - 0.042 13.9 0.9 0.054 13.5 0.9 1.1 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase AAA_5 PF07728.14 EON31698.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Phage_holin_3_6 PF07332.11 EON31698.1 - 0.31 11.1 3.6 0.48 10.5 3.6 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MraZ PF02381.18 EON31699.1 - 4.5e-40 135.5 0.0 4.9e-20 71.3 0.0 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like Methyltransf_5 PF01795.19 EON31700.1 - 9.6e-104 347.2 0.0 1.1e-103 347.0 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 EON31700.1 - 6.5e-07 30.0 0.1 1.3e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON31700.1 - 2.1e-06 27.6 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON31700.1 - 0.00096 18.7 0.0 0.0032 17.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EON31700.1 - 0.0011 19.7 0.1 0.0035 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain rRNA_methylase PF06962.12 EON31700.1 - 0.0013 18.7 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Putative rRNA methylase Methyltransf_24 PF13578.6 EON31700.1 - 0.003 18.6 1.1 0.28 12.2 0.2 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON31700.1 - 0.013 16.1 0.0 0.03 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2570 PF10828.8 EON31701.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Transpeptidase PF00905.22 EON31702.1 - 1.2e-78 264.4 0.0 1.6e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EON31702.1 - 2.4e-16 60.6 0.0 8.8e-15 55.5 0.0 2.3 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain RskA PF10099.9 EON31702.1 - 0.014 15.7 3.2 0.014 15.7 3.2 2.8 3 1 1 4 4 4 0 Anti-sigma-K factor rskA Beta-lactamase2 PF13354.6 EON31702.1 - 0.035 13.7 0.1 0.2 11.3 0.1 2.2 1 1 0 1 1 1 0 Beta-lactamase enzyme family Mur_ligase_M PF08245.12 EON31703.1 - 6e-45 153.6 0.0 8.8e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EON31703.1 - 2e-20 72.8 0.1 1.3e-18 67.0 0.0 3.1 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EON31703.1 - 2.3e-10 40.6 0.2 4.9e-09 36.4 0.0 2.8 2 0 0 2 2 2 1 Mur ligase family, catalytic domain GRASP55_65 PF04495.14 EON31703.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain MobB PF03205.14 EON31703.1 - 0.2 11.5 2.0 2.5 8.0 0.0 2.9 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.11 EON31703.1 - 0.49 9.6 3.4 0.45 9.8 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain Glycos_transf_4 PF00953.21 EON31705.1 - 9.6e-37 126.4 11.3 9.6e-37 126.4 11.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 EON31705.1 - 1.4e-05 24.4 0.1 3.6e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DUF4271 PF14093.6 EON31705.1 - 4.1 7.2 9.8 3.4 7.5 1.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) Mur_ligase_M PF08245.12 EON31706.1 - 4.5e-20 72.4 0.0 7.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EON31706.1 - 2e-08 34.4 0.7 9.8e-08 32.2 0.3 2.5 2 1 1 3 3 3 1 Mur ligase family, glutamate ligase domain AlaDh_PNT_C PF01262.21 EON31706.1 - 0.0073 15.6 2.1 0.014 14.7 2.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 EON31706.1 - 0.056 13.4 0.5 0.15 12.0 0.5 1.7 1 0 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.19 EON31706.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON31706.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Oxidored_nitro PF00148.19 EON31706.1 - 0.15 10.8 0.9 0.81 8.3 0.1 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase FTSW_RODA_SPOVE PF01098.19 EON31707.1 - 1.1e-111 373.4 26.4 1.3e-111 373.1 26.4 1.0 1 0 0 1 1 1 1 Cell cycle protein HTH_23 PF13384.6 EON31707.1 - 0.11 12.3 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Glyco_transf_28 PF03033.20 EON31708.1 - 2.6e-35 121.5 0.0 4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 EON31708.1 - 1.2e-34 119.6 0.0 1.8e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 EON31708.1 - 0.0057 16.7 0.1 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Mur_ligase PF01225.25 EON31709.1 - 2.4e-23 82.3 0.3 8.8e-23 80.4 0.1 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 EON31709.1 - 1.2e-21 76.7 0.3 4.5e-21 74.9 0.1 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 EON31709.1 - 7.5e-21 75.0 0.0 1.3e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain POTRA_1 PF08478.10 EON31710.1 - 8.2e-14 51.7 0.1 1.7e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 POTRA domain, FtsQ-type FtsQ PF03799.15 EON31710.1 - 1.2e-06 29.3 0.0 2.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Cell division protein FtsQ Tubulin PF00091.25 EON31711.1 - 4.9e-39 134.6 0.1 9e-39 133.7 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EON31711.1 - 6.5e-37 125.7 2.0 1.6e-36 124.5 2.0 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 EON31711.1 - 0.034 14.0 0.8 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Cu-oxidase_4 PF02578.15 EON31712.1 - 1.4e-68 230.9 0.0 1.6e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Ala_racemase_N PF01168.20 EON31713.1 - 4.9e-16 59.0 0.1 6.1e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SepF PF04472.12 EON31714.1 - 2.7e-24 85.2 0.0 4.3e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Cell division protein SepF YGGT PF02325.17 EON31715.1 - 6e-09 36.2 9.2 7.5e-09 35.9 9.2 1.1 1 0 0 1 1 1 1 YGGT family MIG-14_Wnt-bd PF06664.12 EON31715.1 - 0.31 10.2 3.2 0.8 8.9 3.0 1.7 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion DivIVA PF05103.13 EON31716.1 - 4.2e-22 78.6 14.4 2.2e-12 47.2 0.0 3.3 2 1 1 3 3 3 3 DivIVA protein UPF0242 PF06785.11 EON31716.1 - 0.0081 16.3 9.4 0.95 9.5 8.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Pox_A_type_inc PF04508.12 EON31716.1 - 0.016 15.1 1.3 0.1 12.5 0.1 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HrpE PF06188.12 EON31716.1 - 0.023 14.6 17.5 0.099 12.5 8.0 2.9 2 1 1 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E Surfac_D-trimer PF09006.11 EON31716.1 - 0.051 13.5 0.5 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DASH_Spc19 PF08287.11 EON31716.1 - 0.064 13.2 0.0 0.064 13.2 0.0 2.7 2 1 0 2 2 2 0 Spc19 Apolipoprotein PF01442.18 EON31716.1 - 0.064 13.1 26.9 0.19 11.6 19.8 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DivIC PF04977.15 EON31716.1 - 0.086 12.6 0.1 0.086 12.6 0.1 3.5 2 1 2 4 4 4 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 EON31716.1 - 0.21 11.8 13.8 0.27 11.5 9.5 2.3 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 EON31716.1 - 0.33 11.2 0.0 0.33 11.2 0.0 3.1 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 TetR_C_13 PF16925.5 EON31716.1 - 0.73 9.8 3.2 4.4 7.3 0.8 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4407 PF14362.6 EON31716.1 - 1.1 8.6 18.9 17 4.6 18.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BMFP PF04380.13 EON31716.1 - 1.6 9.2 12.7 1.8 9.1 0.6 3.9 2 1 0 3 3 3 0 Membrane fusogenic activity Exonuc_VII_L PF02601.15 EON31716.1 - 3 7.3 11.9 5.9 6.4 11.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit V-ATPase_G_2 PF16999.5 EON31716.1 - 4.1 7.9 29.4 4.6 7.7 17.9 3.9 2 1 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Cep57_CLD_2 PF14197.6 EON31716.1 - 4.8 7.3 14.3 0.41 10.8 1.1 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 SLC35F PF06027.12 EON31717.1 - 0.12 11.8 0.6 0.17 11.3 0.6 1.1 1 0 0 1 1 1 0 Solute carrier family 35 Cytochrom_C_asm PF01578.20 EON31717.1 - 0.77 9.5 3.8 1 9.1 3.8 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein FUN14 PF04930.15 EON31717.1 - 6.4 7.3 5.0 9.9 6.7 5.0 1.2 1 0 0 1 1 1 0 FUN14 family tRNA-synt_1 PF00133.22 EON31718.1 - 2.7e-183 610.5 0.0 3.8e-183 610.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EON31718.1 - 9.1e-24 84.2 0.0 1.5e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EON31718.1 - 6.3e-16 58.1 0.1 3.8e-07 29.2 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EON31718.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EON31718.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 SnoaL_2 PF12680.7 EON31719.1 - 0.003 18.2 0.1 0.0086 16.7 0.1 1.9 1 0 0 1 1 1 1 SnoaL-like domain TetR_C_33 PF13305.6 EON31720.1 - 6.2e-23 81.5 5.2 6.2e-23 81.5 5.2 2.3 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON31720.1 - 3.8e-06 26.6 0.1 1.4e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 EON31720.1 - 0.0099 15.6 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EON31720.1 - 0.026 14.3 0.9 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain TnsD PF15978.5 EON31720.1 - 0.23 10.4 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D F420H2_quin_red PF04075.14 EON31721.1 - 1.4e-07 31.7 0.8 1.8e-07 31.4 0.8 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 EON31721.1 - 0.097 12.8 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) IMS PF00817.20 EON31722.1 - 4.8e-35 120.8 0.0 7.2e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EON31722.1 - 2.7e-16 60.3 0.8 4.9e-16 59.5 0.4 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EON31722.1 - 5.9e-08 32.6 0.1 1.7e-07 31.1 0.1 1.8 2 0 0 2 2 2 1 IMS family HHH motif DUF3553 PF12073.8 EON31722.1 - 0.058 13.1 4.2 0.18 11.6 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3553) HHH_5 PF14520.6 EON31722.1 - 0.97 10.1 3.2 0.83 10.3 0.1 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain Asparaginase PF00710.20 EON31723.1 - 2.1e-46 157.9 1.1 4.3e-46 156.9 1.1 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EON31723.1 - 1.7e-23 83.0 0.5 1.1e-22 80.4 0.1 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DUF4878 PF12870.7 EON31725.1 - 0.13 12.6 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Peptidase_A8 PF01252.18 EON31727.1 - 7.1e-34 117.1 4.5 8.5e-34 116.8 4.5 1.1 1 0 0 1 1 1 1 Signal peptidase (SPase) II YfhO PF09586.10 EON31727.1 - 1.1 7.4 2.5 1.4 7.0 2.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4175 PF13779.6 EON31727.1 - 2.3 6.0 5.9 0.23 9.4 1.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF4051 PF13260.6 EON31727.1 - 7.1 6.4 7.6 14 5.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4051) PseudoU_synth_2 PF00849.22 EON31728.1 - 6.4e-29 101.1 0.0 9.6e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EON31728.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 S4 domain Pkinase PF00069.25 EON31729.1 - 6.4e-35 120.8 0.0 9.6e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON31729.1 - 3.1e-20 72.6 0.0 3.9e-15 55.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EON31729.1 - 0.0025 16.6 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EON31729.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EON31729.1 - 0.11 12.4 4.7 0.21 11.5 0.2 2.9 1 1 1 3 3 3 0 Phosphotransferase enzyme family DNA_pol3_alpha PF07733.12 EON31730.1 - 3.9e-90 302.0 0.0 9e-90 300.8 0.0 1.6 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 EON31730.1 - 7.8e-63 210.8 0.0 1.3e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 EON31730.1 - 1.9e-46 158.4 0.0 4.4e-46 157.2 0.0 1.7 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 EON31730.1 - 3.4e-24 84.9 0.0 7.9e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 EON31730.1 - 3.6e-05 23.7 0.0 0.00019 21.3 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain SGL PF08450.12 EON31732.1 - 0.00013 21.6 0.0 0.00056 19.6 0.0 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EON31732.1 - 0.072 13.2 0.3 2.7 8.2 0.0 3.1 2 0 0 2 2 2 0 NHL repeat PALP PF00291.25 EON31733.1 - 1.2e-72 244.8 8.6 8.3e-72 242.1 8.6 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EON31733.1 - 2.8e-26 91.1 0.0 4.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase ABC2_membrane_3 PF12698.7 EON31734.1 - 2e-43 148.8 5.7 2.3e-43 148.6 5.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON31734.1 - 8.3e-09 35.1 18.5 1.1e-08 34.7 18.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EON31734.1 - 0.00017 21.1 12.6 0.00017 21.1 12.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EON31735.1 - 1.6e-28 99.9 0.0 2.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31735.1 - 7.4e-14 52.2 0.1 2.2e-08 34.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EON31735.1 - 9.3e-08 32.7 0.0 1.6e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 EON31735.1 - 0.0024 18.4 0.0 0.0034 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EON31735.1 - 0.005 16.3 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MukB PF04310.12 EON31735.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA_29 PF13555.6 EON31735.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EON31735.1 - 0.038 14.2 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EON31735.1 - 0.11 12.1 0.3 0.27 11.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EON31735.1 - 0.22 11.2 0.0 0.5 10.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 EON31736.1 - 0.012 14.7 10.1 0.016 14.3 10.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein HTH_3 PF01381.22 EON31737.1 - 4.3e-09 36.3 0.0 5.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON31737.1 - 2e-06 28.0 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EON31737.1 - 0.0029 17.6 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EON31737.1 - 0.004 17.6 0.0 0.0054 17.1 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Pyr_redox_3 PF13738.6 EON31738.1 - 1.4e-17 64.0 0.0 5.7e-17 61.9 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON31738.1 - 6.3e-13 48.6 0.0 1.4e-10 41.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EON31738.1 - 8.9e-10 37.6 0.0 1.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EON31738.1 - 2e-08 33.8 0.0 1.3e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EON31738.1 - 2.3e-05 24.5 0.6 0.00039 20.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON31738.1 - 0.001 19.0 0.1 1.6 8.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EON31738.1 - 0.0014 19.1 0.0 0.65 10.6 0.0 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON31738.1 - 0.0048 16.2 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EON31738.1 - 0.016 14.3 1.0 0.026 13.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EON31738.1 - 0.017 14.4 0.0 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Amidohydro_2 PF04909.14 EON31738.1 - 0.055 13.3 0.7 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Amidohydrolase DAO PF01266.24 EON31738.1 - 0.058 13.0 11.0 0.39 10.3 0.4 3.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EON31738.1 - 0.07 12.4 0.3 1.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EON31738.1 - 0.22 12.0 0.1 24 5.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding ECH_1 PF00378.20 EON31739.1 - 1.4e-34 119.5 0.0 1.7e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31739.1 - 5.6e-14 52.4 0.6 1.2e-13 51.3 0.6 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EON31739.1 - 0.00039 20.4 0.2 0.06 13.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase family S49 XdhC_C PF13478.6 EON31740.1 - 5.6e-38 130.3 0.0 1.1e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 EON31740.1 - 6e-21 74.4 4.3 6e-21 74.4 4.3 3.3 4 0 0 4 4 4 1 XdhC and CoxI family IclR PF01614.18 EON31741.1 - 2.7e-35 121.0 0.0 4.3e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EON31741.1 - 4.5e-15 55.2 0.3 4.5e-15 55.2 0.3 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON31741.1 - 1.4e-09 37.7 0.2 4.1e-09 36.2 0.2 1.8 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EON31741.1 - 7.7e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 EON31741.1 - 6.2e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 EON31741.1 - 7.3e-06 25.8 0.0 3.2e-05 23.7 0.0 2.0 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 EON31741.1 - 4.9e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EON31741.1 - 0.00023 20.7 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EON31741.1 - 0.00072 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 EON31741.1 - 0.0012 18.8 0.5 0.02 15.0 0.1 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain Penicillinase_R PF03965.16 EON31741.1 - 0.0036 17.6 0.0 0.0095 16.3 0.0 1.7 2 0 0 2 2 1 1 Penicillinase repressor DprA_WH PF17782.1 EON31741.1 - 0.004 17.2 0.7 0.021 14.9 0.7 2.3 1 0 0 1 1 1 1 DprA winged helix domain HTH_23 PF13384.6 EON31741.1 - 0.0065 16.2 0.0 0.021 14.6 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_5 PF01022.20 EON31741.1 - 0.007 16.2 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_3 PF01381.22 EON31741.1 - 0.0083 16.2 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix Rrf2 PF02082.20 EON31741.1 - 0.0087 16.4 0.0 0.026 14.9 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_38 PF13936.6 EON31741.1 - 0.01 15.6 0.1 0.028 14.2 0.1 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_36 PF13730.6 EON31741.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 EON31741.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 EON31741.1 - 0.015 15.4 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EON31741.1 - 0.02 14.3 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 EON31741.1 - 0.022 14.8 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_6 PF01418.17 EON31741.1 - 0.026 14.5 0.3 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Sigma54_DBD PF04552.13 EON31741.1 - 0.044 13.5 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HTH_Tnp_4 PF13613.6 EON31741.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_17 PF12728.7 EON31741.1 - 0.15 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain BCCT PF02028.17 EON31742.1 - 3.1e-177 589.9 42.5 3.5e-177 589.7 42.5 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter GCV_T PF01571.21 EON31743.1 - 1.3e-71 241.0 0.1 2.9e-71 239.9 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EON31743.1 - 1.7e-50 172.6 3.3 2.5e-50 172.0 3.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 EON31743.1 - 4.5e-16 58.9 0.3 5.3e-15 55.5 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 EON31743.1 - 1e-13 51.0 0.2 2.9e-13 49.5 0.2 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_2 PF07992.14 EON31743.1 - 4.6e-05 22.8 0.2 0.032 13.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON31743.1 - 0.00016 21.8 0.0 0.00067 19.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON31743.1 - 0.00039 19.6 1.4 0.00064 18.9 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EON31743.1 - 0.00044 20.8 0.6 0.0023 18.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EON31743.1 - 0.0016 18.7 0.1 0.0073 16.6 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain SoxG PF04268.12 EON31743.1 - 0.0018 18.4 0.0 0.0075 16.4 0.0 2.1 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family NAD_binding_9 PF13454.6 EON31743.1 - 0.0019 18.2 2.2 0.66 10.0 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EON31743.1 - 0.0036 16.2 0.7 0.03 13.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 EON31743.1 - 0.0039 16.5 2.0 0.045 13.0 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 EON31743.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EON31743.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EON31743.1 - 0.015 14.5 0.0 0.63 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EON31743.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 EON31743.1 - 0.18 12.0 0.2 0.38 11.0 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Formyl_trans_N PF00551.19 EON31744.1 - 3.1e-38 131.3 0.0 3.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT_6 PF13740.6 EON31744.1 - 0.0088 16.0 0.2 0.032 14.2 0.0 2.1 2 2 1 3 3 3 1 ACT domain SoxG PF04268.12 EON31745.1 - 5.7e-24 84.9 0.1 6.9e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family GCV_T PF01571.21 EON31745.1 - 1.8e-06 27.5 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T PF01571.21 EON31746.1 - 6.7e-73 245.2 0.1 9.3e-73 244.7 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SO_alpha_A3 PF17806.1 EON31746.1 - 2e-30 104.9 0.1 4.8e-30 103.7 0.1 1.7 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Pyr_redox_2 PF07992.14 EON31746.1 - 1.8e-19 70.1 0.1 3.2e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GCV_T_C PF08669.11 EON31746.1 - 3.8e-18 65.2 2.9 9e-17 60.8 0.0 3.5 3 0 0 3 3 3 1 Glycine cleavage T-protein C-terminal barrel domain Fer2_4 PF13510.6 EON31746.1 - 4.3e-18 65.1 0.4 5.9e-17 61.5 0.0 3.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_oxidored PF12831.7 EON31746.1 - 1e-11 44.9 0.3 1.6e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON31746.1 - 4.2e-11 42.2 0.3 2.8e-08 32.9 0.5 2.6 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EON31746.1 - 5.6e-09 36.1 1.3 2.4e-08 34.1 0.1 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON31746.1 - 1.2e-07 31.7 9.5 3.7e-07 30.1 7.2 3.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON31746.1 - 4.7e-07 29.2 10.6 0.00011 21.5 10.6 3.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EON31746.1 - 7.5e-07 28.7 0.1 2.9e-06 26.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EON31746.1 - 5.1e-06 27.0 0.1 0.092 13.3 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON31746.1 - 7.2e-06 25.3 0.9 1.6e-05 24.2 0.9 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EON31746.1 - 2.2e-05 23.8 0.1 0.0094 15.2 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 EON31746.1 - 4e-05 23.8 0.1 0.00049 20.3 0.1 2.3 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Thi4 PF01946.17 EON31746.1 - 0.00011 21.5 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EON31746.1 - 0.0005 19.0 0.3 0.093 11.6 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 EON31746.1 - 0.00082 18.8 1.5 0.33 10.2 0.7 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EON31746.1 - 0.0031 16.9 0.1 0.0062 15.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON31746.1 - 0.028 13.5 2.6 0.042 12.9 0.7 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EON31746.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SoxD PF04267.12 EON31747.1 - 4.1e-33 113.3 1.5 5.2e-33 113.0 1.5 1.1 1 0 0 1 1 1 1 Sarcosine oxidase, delta subunit family Lar_restr_allev PF14354.6 EON31747.1 - 0.0027 18.0 0.1 0.0036 17.7 0.1 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-HYPF PF07503.12 EON31747.1 - 0.024 14.4 0.2 0.05 13.4 0.2 1.5 1 0 0 1 1 1 0 HypF finger F-box_5 PF18511.1 EON31747.1 - 0.05 13.2 0.5 0.08 12.5 0.5 1.3 1 0 0 1 1 1 0 F-box DAO PF01266.24 EON31748.1 - 7e-58 196.9 7.3 8e-58 196.7 7.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON31748.1 - 3.9e-07 30.2 3.1 8.4e-07 29.1 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON31748.1 - 2.5e-05 23.6 3.7 0.005 16.0 1.5 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EON31748.1 - 0.0001 21.6 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EON31748.1 - 0.00021 20.6 0.1 0.0041 16.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON31748.1 - 0.001 18.4 2.3 0.013 14.8 0.7 2.4 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 EON31748.1 - 0.002 17.1 2.2 0.3 9.9 1.3 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 EON31748.1 - 0.0029 17.0 1.6 0.025 13.9 1.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON31748.1 - 0.0059 17.2 2.9 2.7 8.6 1.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON31748.1 - 0.023 13.9 0.4 0.059 12.6 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EON31748.1 - 0.075 11.8 0.3 0.36 9.6 0.1 2.0 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 EON31748.1 - 0.083 12.9 0.3 3.4 7.6 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EON31748.1 - 0.18 10.4 0.4 12 4.4 0.6 2.7 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_1 PF00175.21 EON31749.1 - 2.2e-19 70.1 0.0 3.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON31749.1 - 1.2e-15 57.6 0.0 6.4e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 EON31749.1 - 8.2e-12 44.9 0.3 1.7e-11 43.9 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 EON31749.1 - 0.0001 22.4 0.5 0.0051 17.0 0.0 2.6 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Fer2_4 PF13510.6 EON31749.1 - 0.00041 20.4 0.1 0.0027 17.7 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 EON31749.1 - 0.033 14.0 1.8 0.092 12.6 1.8 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ring_hydroxyl_A PF00848.19 EON31750.1 - 8.2e-43 146.9 0.0 1.4e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EON31750.1 - 3.3e-16 59.0 0.0 6.5e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SDH_alpha PF03313.15 EON31751.1 - 5.8e-98 327.7 4.5 7.6e-98 327.3 4.5 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EON31751.1 - 3.8e-52 176.8 0.0 6e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Serine dehydratase beta chain FCD PF07729.12 EON31752.1 - 1.8e-28 99.4 6.9 3.5e-28 98.5 6.9 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON31752.1 - 3.2e-16 58.7 1.5 3.2e-16 58.7 1.5 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EON31752.1 - 0.016 14.7 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EON31752.1 - 0.026 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Bmp PF02608.14 EON31753.1 - 1e-31 110.1 0.9 1.3e-31 109.7 0.9 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like DUF1834 PF08873.11 EON31753.1 - 0.0055 16.5 0.1 0.0086 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1834) LPAM_2 PF13627.6 EON31753.1 - 2.4 8.1 5.8 4.4 7.3 5.8 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ABC_tran PF00005.27 EON31754.1 - 3.8e-47 160.2 0.0 8.9e-28 97.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON31754.1 - 0.00016 21.6 0.5 0.12 12.2 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EON31754.1 - 0.00055 19.3 0.1 0.35 10.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 EON31754.1 - 0.00073 19.2 0.4 0.004 16.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON31754.1 - 0.0036 17.2 0.2 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EON31754.1 - 0.0036 17.7 0.1 0.024 15.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EON31754.1 - 0.026 15.0 0.0 0.039 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON31754.1 - 0.027 14.7 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EON31754.1 - 0.03 13.7 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EON31754.1 - 0.031 14.4 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_27 PF13514.6 EON31754.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 EON31755.1 - 6.2e-34 117.4 41.3 6.2e-34 117.4 41.3 2.0 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 EON31756.1 - 4e-31 108.2 39.4 5.1e-31 107.8 39.4 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component OCD_Mu_crystall PF02423.15 EON31757.1 - 9e-71 238.4 2.9 1e-70 238.2 2.9 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EON31757.1 - 2.4e-07 30.9 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EON31757.1 - 0.0038 17.4 0.0 0.061 13.5 0.0 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase dCMP_cyt_deam_1 PF00383.23 EON31758.1 - 8.9e-20 70.5 0.0 5.1e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EON31758.1 - 2.3e-17 63.1 0.0 2.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EON31758.1 - 0.024 14.7 1.1 0.042 13.9 1.1 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase SNAD4 PF18750.1 EON31758.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EON31758.1 - 0.23 11.5 0.0 0.31 11.1 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 ALO PF04030.14 EON31759.1 - 2.6e-69 233.9 0.0 3.1e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EON31759.1 - 3.3e-21 75.5 4.2 5.1e-21 74.9 4.2 1.3 1 0 0 1 1 1 1 FAD binding domain Chol_subst-bind PF09129.11 EON31759.1 - 0.092 11.7 0.0 1.3 7.9 0.0 2.5 1 1 1 3 3 3 0 Cholesterol oxidase, substrate-binding Ala_racemase_N PF01168.20 EON31760.1 - 1e-09 38.4 1.0 1.5e-09 37.9 1.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TetR_N PF00440.23 EON31761.1 - 5.4e-09 35.7 0.1 9.1e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON31761.1 - 0.009 16.2 0.6 0.067 13.4 0.0 2.4 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NAPRTase_C PF17956.1 EON31761.1 - 0.17 12.3 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain Lactamase_B_2 PF12706.7 EON31762.1 - 5.2e-41 140.4 1.1 8.6e-41 139.7 1.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EON31762.1 - 3.1e-16 59.7 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EON31762.1 - 0.057 13.4 5.5 5.9 6.8 3.8 2.6 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily E1-E2_ATPase PF00122.20 EON31763.1 - 5.1e-42 143.4 0.8 5.1e-42 143.4 0.8 3.3 3 1 2 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 EON31763.1 - 2.3e-19 70.5 0.8 4e-19 69.7 0.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EON31763.1 - 4.1e-06 26.6 7.5 4.1e-06 26.6 7.5 3.3 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EON31763.1 - 1.4e-05 25.0 0.3 2.4e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF998 PF06197.13 EON31763.1 - 0.00029 20.5 5.0 0.00029 20.5 5.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF998) MT0933_antitox PF14013.6 EON31764.1 - 2.1e-10 40.7 2.3 3.1e-10 40.2 2.3 1.3 1 0 0 1 1 1 1 MT0933-like antitoxin protein Pur_DNA_glyco PF02245.16 EON31765.1 - 2.6e-55 186.6 0.0 3.1e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Polyketide_cyc2 PF10604.9 EON31766.1 - 7.6e-15 55.4 0.1 8.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SBP_bac_11 PF13531.6 EON31767.1 - 2.3e-11 43.9 9.8 2.3e-11 43.9 9.8 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein VWA PF00092.28 EON31767.1 - 3.5e-08 33.9 0.0 7.4e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EON31767.1 - 9.9e-06 25.6 0.0 3.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EON31767.1 - 0.0032 16.9 0.1 0.066 12.6 0.0 2.3 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EON31767.1 - 0.0063 17.2 0.0 0.058 14.1 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain PepSY_TM PF03929.16 EON31767.1 - 0.077 12.7 0.1 0.29 10.8 0.0 2.0 3 0 0 3 3 3 0 PepSY-associated TM region FMN_bind PF04205.14 EON31768.1 - 2.6e-05 24.7 2.1 2.6e-05 24.7 2.1 2.1 2 0 0 2 2 2 1 FMN-binding domain ApbE PF02424.15 EON31769.1 - 5.3e-33 114.6 0.1 6.8e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 ApbE family DUF5607 PF18355.1 EON31769.1 - 0.031 14.7 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) NAD_binding_1 PF00175.21 EON31770.1 - 1.5e-06 28.8 0.0 2.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON31770.1 - 1.9e-05 24.8 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NQR2_RnfD_RnfE PF03116.15 EON31770.1 - 3e-05 23.6 18.7 0.00019 21.0 4.6 2.3 1 1 1 2 2 2 2 NQR2, RnfD, RnfE family Pro_dh PF01619.18 EON31771.1 - 7e-28 98.0 0.0 1e-27 97.5 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase DUF4911 PF16256.5 EON31771.1 - 0.037 14.0 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Aldedh PF00171.22 EON31772.1 - 1.2e-95 320.7 0.0 1.5e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HTH_30 PF13556.6 EON31773.1 - 2.9e-23 81.4 1.5 8.2e-23 80.0 1.5 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EON31773.1 - 0.00012 22.3 0.6 0.00012 22.3 0.6 4.0 2 2 1 3 3 3 1 GGDEF-like domain PucR PF07905.11 EON31773.1 - 0.0028 17.9 0.4 0.0086 16.4 0.1 2.1 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family HTH_8 PF02954.19 EON31773.1 - 0.0058 16.4 0.1 0.033 14.0 0.0 2.3 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 EON31773.1 - 0.0058 16.7 0.1 0.046 13.8 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_1 PF00126.27 EON31773.1 - 0.028 14.4 0.1 0.088 12.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family P22_Cro PF14549.6 EON31773.1 - 0.15 12.0 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro DprA_WH PF17782.1 EON31773.1 - 2.5 8.3 7.7 0.27 11.4 0.4 3.2 3 0 0 3 3 3 0 DprA winged helix domain adh_short PF00106.25 EON31774.1 - 3.8e-19 68.9 0.0 5.7e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31774.1 - 1.4e-13 51.0 0.0 1.9e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31774.1 - 5.4e-05 23.2 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31774.1 - 5.6e-05 22.7 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 EON31774.1 - 0.033 13.6 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ThiF PF00899.21 EON31774.1 - 0.098 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 EON31774.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1490 PF07371.12 EON31774.1 - 3.1 7.9 6.9 1.1 9.4 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) GSIII_N PF12437.8 EON31775.1 - 1.3e-72 242.7 0.0 2.6e-72 241.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EON31775.1 - 4.7e-40 136.1 0.4 7.6e-40 135.4 0.4 1.3 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EON31775.1 - 7.1e-22 77.9 0.0 1.6e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain TauD PF02668.16 EON31775.1 - 0.042 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family G_glu_transpept PF01019.21 EON31776.1 - 2.7e-147 491.7 0.0 3.1e-147 491.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Polyketide_cyc2 PF10604.9 EON31777.1 - 9.4e-11 42.2 0.3 1.1e-10 41.9 0.3 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON31777.1 - 2.9e-06 27.5 0.0 3.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 EON31777.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.5 1 1 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) MFS_1 PF07690.16 EON31778.1 - 1.1e-38 133.0 44.7 1.1e-38 133.0 44.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Claudin_2 PF13903.6 EON31778.1 - 0.0076 16.0 4.2 0.0076 16.0 4.2 2.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TetR_N PF00440.23 EON31779.1 - 3.3e-13 49.2 0.0 5.4e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_36 PF18598.1 EON31779.1 - 2.1e-05 24.4 0.1 4.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_35 PF18556.1 EON31779.1 - 0.0013 18.8 0.3 0.0037 17.4 0.1 1.9 2 0 0 2 2 2 1 Bacterial Tetracyclin repressor, C-terminal domain HTH_7 PF02796.15 EON31779.1 - 0.0019 18.2 0.1 0.0035 17.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF2236 PF09995.9 EON31780.1 - 1.5e-19 71.1 0.4 2.8e-19 70.2 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TAT_signal PF10518.9 EON31780.1 - 3.1e-05 23.6 2.5 6.5e-05 22.6 2.5 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Acyl_transf_3 PF01757.22 EON31781.1 - 2.1e-19 69.8 29.0 2.5e-19 69.6 29.0 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF423 PF04241.15 EON31781.1 - 0.077 13.2 0.8 0.21 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF423) AAA_16 PF13191.6 EON31782.1 - 2.2e-11 44.4 7.8 6.7e-07 29.8 0.1 4.1 3 1 1 4 4 4 2 AAA ATPase domain GerE PF00196.19 EON31782.1 - 5.2e-11 41.9 0.0 9.5e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON31782.1 - 8.4e-06 25.4 3.0 7.1e-05 22.4 0.1 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON31782.1 - 1.6e-05 24.3 0.3 4.1e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Trans_reg_C PF00486.28 EON31782.1 - 2.7e-05 24.2 0.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HTH_38 PF13936.6 EON31782.1 - 3.4e-05 23.5 0.4 0.00011 21.9 0.4 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_22 PF13401.6 EON31782.1 - 5.3e-05 23.5 0.0 0.02 15.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain HTH_23 PF13384.6 EON31782.1 - 6e-05 22.7 1.0 0.00052 19.7 0.2 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EON31782.1 - 0.00037 20.6 0.4 0.00037 20.6 0.4 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 EON31782.1 - 0.0014 18.4 0.1 0.0044 16.8 0.1 1.9 1 1 0 1 1 1 1 HTH DNA binding domain HTH_29 PF13551.6 EON31782.1 - 0.0032 17.4 1.4 0.03 14.3 0.2 2.9 2 0 0 2 2 2 1 Winged helix-turn helix DUF742 PF05331.11 EON31782.1 - 0.0034 17.2 0.2 0.015 15.1 0.2 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_40 PF14493.6 EON31782.1 - 0.0051 17.2 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_5 PF07728.14 EON31782.1 - 0.0059 16.6 0.0 0.026 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_24 PF13412.6 EON31782.1 - 0.0094 15.5 0.1 0.032 13.8 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding IstB_IS21 PF01695.17 EON31782.1 - 0.023 14.4 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein HTH_11 PF08279.12 EON31782.1 - 0.026 14.5 0.4 0.28 11.2 0.1 2.7 3 0 0 3 3 3 0 HTH domain HTH_AsnC-type PF13404.6 EON31782.1 - 0.026 14.4 0.7 0.026 14.4 0.7 4.1 4 0 0 4 4 3 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 EON31782.1 - 0.029 14.3 0.4 0.029 14.3 0.4 3.7 3 0 0 3 3 3 0 MarR family ATPase_2 PF01637.18 EON31782.1 - 0.04 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_IclR PF09339.10 EON31782.1 - 0.31 10.9 5.3 0.23 11.3 0.6 3.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain TPR_14 PF13428.6 EON31782.1 - 0.46 11.4 28.1 1.5 9.9 1.1 8.1 6 1 1 7 7 6 0 Tetratricopeptide repeat HTH_20 PF12840.7 EON31782.1 - 0.64 10.1 11.1 0.15 12.1 1.1 4.6 3 1 0 3 3 2 0 Helix-turn-helix domain Phage_holin_3_6 PF07332.11 EON31783.1 - 0.0071 16.4 2.1 0.0083 16.2 2.1 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2613 PF11021.8 EON31783.1 - 0.57 10.3 7.7 0.54 10.4 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) DUF202 PF02656.15 EON31783.1 - 1.1 9.7 5.0 2.7 8.5 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) HTH_18 PF12833.7 EON31784.1 - 5.4e-19 68.2 1.7 8.4e-19 67.6 1.7 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 EON31784.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 EON31784.1 - 1.3e-11 44.3 0.0 5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_1 PF01527.20 EON31784.1 - 0.062 13.6 0.1 0.44 10.9 0.1 2.3 3 0 0 3 3 3 0 Transposase DprA_WH PF17782.1 EON31784.1 - 0.08 13.1 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 DprA winged helix domain TetR_N PF00440.23 EON31784.1 - 0.088 12.6 0.1 0.76 9.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family BPL_N PF09825.9 EON31784.1 - 0.17 10.9 0.3 0.26 10.3 0.3 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal adh_short PF00106.25 EON31786.1 - 2.6e-39 134.7 0.0 4e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31786.1 - 1.2e-26 93.7 0.2 1.5e-26 93.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON31786.1 - 4.1e-10 39.9 0.5 7e-10 39.1 0.5 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EON31786.1 - 1.6e-08 34.3 0.0 4.8e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EON31786.1 - 4.7e-07 29.9 0.1 1.8e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31786.1 - 1.1e-05 25.0 0.1 3.8e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EON31786.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EON31786.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family LytR_C PF13399.6 EON31786.1 - 0.057 14.4 0.5 0.13 13.2 0.1 1.8 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator TP_methylase PF00590.20 EON31787.1 - 2.1e-27 96.5 2.2 2.7e-27 96.1 2.2 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UPF0014 PF03649.13 EON31788.1 - 2.4e-45 154.8 23.4 3e-45 154.5 23.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) DUF4079 PF13301.6 EON31788.1 - 0.0022 18.1 2.1 0.0022 18.1 2.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) EcKinase PF02958.20 EON31788.1 - 0.18 11.1 0.3 0.24 10.7 0.3 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase FUSC_2 PF13515.6 EON31788.1 - 3.5 7.8 30.3 0.18 12.0 5.5 2.9 2 1 1 3 3 3 0 Fusaric acid resistance protein-like Inositol_P PF00459.25 EON31789.1 - 1.9e-30 106.3 1.2 3.8e-18 66.0 0.0 2.1 1 1 1 2 2 2 2 Inositol monophosphatase family H2TH PF06831.14 EON31790.1 - 1.3e-16 60.4 0.0 2.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EON31790.1 - 9.8e-12 45.5 0.0 3.9e-11 43.6 0.0 2.1 3 1 0 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 EON31790.1 - 1.4e-07 31.2 1.2 2.4e-07 30.5 1.2 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FbpA PF05833.11 EON31790.1 - 0.00055 18.8 0.0 0.00072 18.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) zf-TFIIB PF13453.6 EON31790.1 - 0.016 14.6 1.9 0.029 13.7 1.9 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Arg_repressor_C PF02863.18 EON31790.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain zf-RRN7 PF11781.8 EON31790.1 - 2.8 7.7 4.7 12 5.7 4.7 2.0 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 adh_short PF00106.25 EON31791.1 - 1.8e-35 122.1 0.2 2.3e-35 121.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31791.1 - 3.3e-29 102.1 2.0 4e-29 101.8 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31791.1 - 1.2e-10 41.6 0.5 1.6e-10 41.2 0.5 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON31791.1 - 1.4e-06 28.3 1.2 1.8e-06 27.9 1.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF4349 PF14257.6 EON31791.1 - 0.05 13.0 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) PGI PF00342.19 EON31794.1 - 1.5e-205 683.4 0.0 1.7e-205 683.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CM_2 PF01817.21 EON31795.1 - 1.6e-08 34.8 0.2 2.1e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Chorismate mutase type II DUF1192 PF06698.11 EON31795.1 - 0.0072 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) LPP PF04728.13 EON31795.1 - 0.17 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper UvrD-helicase PF00580.21 EON31798.1 - 1.6e-75 254.6 0.0 2.8e-75 253.7 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EON31798.1 - 1.5e-67 228.5 0.0 2.7e-67 227.6 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EON31798.1 - 9.9e-34 116.8 0.0 2.1e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EON31798.1 - 1.6e-11 43.8 0.0 4.8e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EON31798.1 - 2.1e-07 30.8 1.5 8e-05 22.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EON31798.1 - 0.08 12.7 0.0 4.6 6.9 0.0 3.0 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Peptidase_M23 PF01551.22 EON31799.1 - 5.3e-31 106.7 0.7 5.3e-31 106.7 0.7 1.7 2 0 0 2 2 2 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 EON31799.1 - 0.0024 17.7 0.3 0.0073 16.1 0.3 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_2 PF08442.10 EON31800.1 - 3.9e-69 232.3 0.4 5.2e-69 231.9 0.4 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EON31800.1 - 5.4e-14 52.3 1.4 1e-13 51.4 1.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EON31800.1 - 2.2e-09 37.1 1.6 5.6e-09 35.8 1.6 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EON31800.1 - 6.2e-07 29.1 0.2 1.8e-06 27.6 0.2 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 EON31800.1 - 0.00022 21.0 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EON31800.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 ATP-grasp domain DUF585 PF04522.12 EON31800.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF585) CoA_binding PF02629.19 EON31801.1 - 2.3e-24 85.9 5.6 6.1e-24 84.5 2.6 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EON31801.1 - 5.4e-15 55.5 1.7 5.4e-15 55.5 1.7 2.3 2 1 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EON31801.1 - 1.4e-11 44.3 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EON31801.1 - 0.00053 20.5 0.1 0.0013 19.2 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain RDD PF06271.12 EON31803.1 - 1.9e-15 57.3 8.1 2.4e-15 56.9 8.1 1.1 1 0 0 1 1 1 1 RDD family Frizzled PF01534.17 EON31803.1 - 0.0059 15.7 2.6 0.0083 15.2 2.6 1.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF1270 PF06900.11 EON31803.1 - 0.15 12.5 0.6 0.15 12.5 0.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) CrgA PF06781.12 EON31803.1 - 8.6 6.5 7.5 1.2 9.3 0.5 2.4 1 1 2 3 3 3 0 Cell division protein CrgA Polyketide_cyc2 PF10604.9 EON31804.1 - 6.3e-22 78.4 2.8 7.3e-22 78.2 2.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EON31804.1 - 1.1e-05 25.7 0.4 1.3e-05 25.4 0.4 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Carboxyl_trans PF01039.22 EON31805.1 - 5.1e-39 134.2 0.3 9.3e-23 80.6 0.0 2.2 2 0 0 2 2 2 2 Carboxyl transferase domain NUDIX PF00293.28 EON31806.1 - 4e-20 72.2 0.5 5.8e-20 71.7 0.5 1.3 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EON31806.1 - 0.0013 18.7 0.0 0.0015 18.5 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 EON31806.1 - 0.0017 17.9 0.1 0.074 12.6 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4916) NUDIX_2 PF13869.6 EON31806.1 - 0.16 11.5 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase Nitroreductase PF00881.24 EON31807.1 - 6.8e-22 78.3 0.0 8.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EON31807.1 - 0.00051 19.7 0.0 0.052 13.1 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase TetR_N PF00440.23 EON31808.1 - 3e-16 58.9 0.1 5.9e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON31808.1 - 4.8e-10 39.7 0.3 9.4e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DUF5336 PF17270.2 EON31809.1 - 1.6e-10 40.9 13.0 5.4e-10 39.2 13.0 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF5336) HlyIII PF03006.20 EON31809.1 - 0.37 10.5 5.2 0.12 12.1 2.2 1.6 2 0 0 2 2 2 0 Haemolysin-III related DUF4389 PF14333.6 EON31809.1 - 0.4 10.6 0.0 0.4 10.6 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4389) DUF202 PF02656.15 EON31809.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MTS PF05175.14 EON31810.1 - 1.2e-06 28.2 0.0 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 EON31810.1 - 0.0015 19.2 0.0 0.0027 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 EON31810.1 - 0.002 18.6 1.6 0.011 16.2 0.1 2.5 2 1 1 3 3 3 1 PrmC N-terminal domain Methyltransf_12 PF08242.12 EON31810.1 - 0.059 14.1 0.0 0.13 13.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain AurF PF11583.8 EON31811.1 - 5.2e-103 344.2 0.0 6e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF Metal_hydrol PF10118.9 EON31811.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase Fer4 PF00037.27 EON31812.1 - 4.9e-09 35.6 21.0 6.5e-08 32.1 5.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EON31812.1 - 3.3e-07 30.8 13.7 5.4e-07 30.1 13.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON31812.1 - 2.3e-06 27.4 4.5 2.3e-06 27.4 4.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain NAD_binding_8 PF13450.6 EON31812.1 - 9.5e-06 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_2 PF12797.7 EON31812.1 - 1.5e-05 24.8 16.5 1.9e-05 24.4 3.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 EON31812.1 - 2e-05 24.6 8.8 4e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 EON31812.1 - 2.8e-05 23.5 0.0 9.2e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 EON31812.1 - 5.8e-05 23.2 11.2 0.0001 22.4 11.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EON31812.1 - 0.0001 23.2 9.8 0.00026 21.9 0.4 2.3 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EON31812.1 - 0.00049 20.2 13.3 0.0043 17.2 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Pyr_redox PF00070.27 EON31812.1 - 0.00097 19.7 0.0 1.6 9.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_4 PF12800.7 EON31812.1 - 0.0024 18.2 4.3 0.0024 18.2 4.3 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 EON31812.1 - 0.0046 17.4 0.1 0.0046 17.4 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 EON31812.1 - 0.026 14.5 0.0 0.072 13.1 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EON31812.1 - 0.04 13.2 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EON31812.1 - 0.11 11.7 0.0 6 6.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EON31812.1 - 0.12 12.9 0.1 0.44 11.0 0.1 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.6 EON31812.1 - 0.31 10.1 0.0 17 4.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_3 PF12798.7 EON31812.1 - 0.9 10.6 24.4 0.11 13.5 8.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EON31812.1 - 0.93 10.1 11.5 0.24 12.0 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain EamA PF00892.20 EON31814.1 - 1.6e-35 122.3 32.9 1.6e-22 80.1 7.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF4131 PF13567.6 EON31814.1 - 0.017 14.8 0.7 0.017 14.8 0.7 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) MDMPI_N PF11716.8 EON31815.1 - 1.5e-09 38.7 2.5 1.5e-09 38.7 2.5 1.8 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain SCP2 PF02036.17 EON31815.1 - 0.003 18.0 0.0 0.021 15.3 0.0 2.1 2 0 0 2 2 2 1 SCP-2 sterol transfer family DinB_2 PF12867.7 EON31815.1 - 0.0066 17.0 0.1 0.012 16.1 0.1 1.4 1 0 0 1 1 1 1 DinB superfamily DEAD PF00270.29 EON31816.1 - 5.7e-42 143.5 0.0 1.2e-41 142.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON31816.1 - 4.5e-23 81.7 0.0 1.9e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON31816.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EccE PF11203.8 EON31816.1 - 2 8.8 9.2 34 4.9 7.7 3.2 2 2 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE HTH_3 PF01381.22 EON31817.1 - 4.7e-17 61.8 0.2 6.9e-17 61.2 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON31817.1 - 1.5e-12 47.7 1.6 3.5e-12 46.5 1.6 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EON31817.1 - 2.2e-07 31.2 0.0 4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 EON31817.1 - 7.1e-07 29.2 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EON31817.1 - 0.0001 22.1 0.1 0.00019 21.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EON31817.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EON31817.1 - 0.0016 18.2 0.5 0.0037 17.0 0.5 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_35 PF13693.6 EON31817.1 - 0.034 14.2 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 EON31817.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Phage_CI_repr PF07022.13 EON31817.1 - 0.16 12.0 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain AzlC PF03591.14 EON31818.1 - 7.4e-28 97.7 11.8 7.4e-28 97.7 11.8 1.6 2 0 0 2 2 2 1 AzlC protein AzlD PF05437.12 EON31819.1 - 1.7e-09 37.8 10.0 1.9e-09 37.6 10.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) Glyco_hydro_1 PF00232.18 EON31820.1 - 2.1e-48 164.9 1.9 1.3e-30 106.2 0.1 2.7 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Lipase_2 PF01674.18 EON31821.1 - 1.9e-13 50.4 0.0 4e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EON31821.1 - 7.2e-08 32.4 0.5 1.1e-07 31.8 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31821.1 - 4.2e-07 30.8 2.0 6.4e-07 30.2 2.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EON31821.1 - 0.00014 21.8 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EON31821.1 - 0.0094 15.3 0.0 0.71 9.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EON31821.1 - 0.013 14.8 0.1 0.02 14.1 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 T4BSS_DotH_IcmK PF12293.8 EON31821.1 - 0.047 12.9 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion DUF900 PF05990.12 EON31821.1 - 0.075 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HTH_31 PF13560.6 EON31821.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2162 PF09930.9 EON31822.1 - 0.023 14.1 0.6 0.035 13.5 0.1 1.5 2 0 0 2 2 2 0 Predicted transporter (DUF2162) TMEM100 PF16311.5 EON31822.1 - 0.024 14.2 0.2 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2721 PF11026.8 EON31822.1 - 0.052 13.4 5.8 0.11 12.4 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) DuoxA PF10204.9 EON31822.1 - 0.052 12.5 0.6 0.35 9.8 0.2 2.0 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF4173 PF13777.6 EON31822.1 - 0.12 11.8 4.7 0.16 11.4 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) LPG_synthase_TM PF03706.13 EON31822.1 - 0.18 11.3 8.8 5.5 6.4 0.0 2.0 1 1 1 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DUF3040 PF11239.8 EON31822.1 - 1.7 8.9 7.4 0.19 12.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) VirB3 PF05101.13 EON31826.1 - 0.0027 17.9 1.2 0.062 13.5 0.1 2.2 2 0 0 2 2 2 1 Type IV secretory pathway, VirB3-like protein DUF3093 PF11292.8 EON31826.1 - 0.025 14.8 0.2 0.025 14.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) LPG_synthase_TM PF03706.13 EON31826.1 - 0.058 12.9 5.9 0.017 14.6 2.9 1.5 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region SIMPL PF04402.14 EON31827.1 - 8.7e-23 81.8 0.0 9.8e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Acetyltransf_3 PF13302.7 EON31828.1 - 5.2e-15 56.3 0.0 8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EON31828.1 - 4.5e-10 39.9 0.0 8.8e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON31828.1 - 1.1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 EON31828.1 - 0.0083 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON31828.1 - 0.087 13.3 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MoeA_N PF03453.17 EON31829.1 - 4.8e-39 133.6 4.5 8.5e-39 132.8 4.5 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EON31829.1 - 4.3e-17 62.1 0.2 7.3e-17 61.4 0.2 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EON31829.1 - 1.5e-16 60.3 0.0 6.8e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) NTP_transferase PF00483.23 EON31830.1 - 1e-27 97.3 0.0 1.4e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON31830.1 - 1.4e-06 28.8 2.1 2.8e-06 27.8 2.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Imm75 PF15660.6 EON31830.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative Immunity protein 75 5-FTHF_cyc-lig PF01812.20 EON31831.1 - 4.2e-34 118.0 0.0 4.7e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Zn-ribbon_8 PF09723.10 EON31832.1 - 1.3e-13 50.8 0.9 2.6e-13 49.8 0.9 1.5 1 0 0 1 1 1 1 Zinc ribbon domain DUF4667 PF15700.5 EON31832.1 - 0.0035 17.5 13.3 0.0044 17.2 13.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) zinc-ribbons_6 PF07191.12 EON31832.1 - 0.014 15.4 0.6 0.036 14.1 0.6 1.6 1 1 0 1 1 1 0 zinc-ribbons C1_4 PF07975.12 EON31832.1 - 0.064 13.5 1.9 0.064 13.5 1.9 2.0 2 1 0 2 2 2 0 TFIIH C1-like domain HypA PF01155.19 EON31832.1 - 0.065 13.3 0.3 0.084 12.9 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 EON31832.1 - 0.13 11.7 1.3 0.23 10.8 0.9 1.7 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_ribbon_SprT PF17283.2 EON31832.1 - 0.13 12.2 3.6 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain CxC7 PF18866.1 EON31832.1 - 0.55 10.4 3.6 11 6.2 0.2 2.4 1 1 1 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases zinc_ribbon_9 PF14369.6 EON31832.1 - 0.68 10.2 4.4 1.6 9.0 3.1 2.3 1 1 1 2 2 2 0 zinc-ribbon Secretin_N_2 PF07655.13 EON31832.1 - 1.1 9.9 21.8 1.5 9.4 21.8 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain NAM-associated PF14303.6 EON31832.1 - 2 9.1 9.7 2.5 8.8 9.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 EON31832.1 - 2.1 8.0 10.5 2.8 7.6 10.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Apt1 PF10351.9 EON31832.1 - 4.5 6.0 13.3 5.4 5.7 13.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 EON31832.1 - 5.3 6.8 8.1 6.3 6.6 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Na_H_antiport_1 PF06965.12 EON31833.1 - 2.1e-127 425.1 28.9 2.3e-127 424.9 28.9 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 ChapFlgA PF13144.6 EON31834.1 - 1.6e-07 31.4 0.0 4e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Chaperone for flagella basal body P-ring formation SAF PF08666.12 EON31834.1 - 1.1e-06 29.1 0.7 3e-06 27.8 0.5 1.9 2 0 0 2 2 2 1 SAF domain RcpC PF16976.5 EON31834.1 - 0.068 13.2 8.5 0.071 13.2 2.7 2.6 2 1 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB MscL PF01741.18 EON31835.1 - 5.2e-33 113.9 3.7 6.4e-33 113.6 3.7 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL TruB_C PF09142.11 EON31837.1 - 0.05 13.4 0.1 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Tnp_22_trimer PF17489.2 EON31837.1 - 0.15 12.1 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 L1 transposable element trimerization domain ABC_membrane PF00664.23 EON31838.1 - 8.9e-34 117.4 8.7 1.3e-33 116.9 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON31838.1 - 3.3e-23 82.7 0.0 5.7e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31838.1 - 0.0021 18.0 0.1 0.96 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON31838.1 - 0.0032 16.9 0.3 0.16 11.4 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EON31838.1 - 0.0074 16.0 0.4 0.014 15.1 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON31838.1 - 0.028 14.2 0.7 0.081 12.7 0.7 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EON31838.1 - 0.35 10.9 0.8 0.58 10.2 0.8 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 EON31838.1 - 0.56 10.7 1.5 0.89 10.0 1.5 1.2 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 EON31839.1 - 1.3e-37 129.9 4.6 1.7e-37 129.6 4.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON31839.1 - 6.6e-30 104.4 0.0 1.3e-29 103.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON31839.1 - 5.2e-05 22.8 0.7 0.028 13.9 0.1 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON31839.1 - 0.00045 20.6 0.5 0.0019 18.6 0.5 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON31839.1 - 0.0051 17.1 1.8 0.018 15.3 0.4 2.5 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 EON31839.1 - 0.0089 15.8 0.3 0.023 14.4 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EON31839.1 - 0.01 14.9 0.4 0.022 13.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EON31839.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EON31839.1 - 0.027 13.8 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EON31839.1 - 0.047 13.4 2.0 0.28 10.9 2.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON31839.1 - 0.094 12.3 3.8 0.44 10.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EON31839.1 - 0.096 12.9 0.7 1.7 8.9 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.8 EON31839.1 - 0.098 10.2 0.6 0.14 9.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_18 PF13238.6 EON31839.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EON31839.1 - 0.14 11.9 0.9 2.4 7.9 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 EON31839.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EON31839.1 - 0.27 11.3 1.4 0.6 10.2 1.4 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 EON31839.1 - 0.27 11.5 1.2 0.73 10.1 1.2 1.7 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EON31839.1 - 1.7 7.4 4.1 0.97 8.2 0.3 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Esterase PF00756.20 EON31840.1 - 6e-29 101.4 0.1 1.7e-28 100.0 0.1 1.6 1 1 0 1 1 1 1 Putative esterase ABC_tran PF00005.27 EON31841.1 - 8.2e-33 113.8 0.0 1.8e-32 112.7 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 EON31841.1 - 3e-31 109.1 0.2 4e-31 108.7 0.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON31841.1 - 4.7e-07 29.5 0.0 2.6e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON31841.1 - 2.8e-06 27.3 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON31841.1 - 0.00011 22.6 0.2 0.00028 21.3 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON31841.1 - 0.00054 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EON31841.1 - 0.0012 19.1 0.0 0.0054 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EON31841.1 - 0.0076 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.6 EON31841.1 - 0.012 15.2 0.1 0.044 13.3 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON31841.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EON31841.1 - 0.014 15.1 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TatC PF00902.18 EON31841.1 - 0.024 14.4 0.0 0.055 13.3 0.0 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF687 PF05095.12 EON31841.1 - 0.026 13.1 0.1 0.048 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) T2SSE PF00437.20 EON31841.1 - 0.031 13.3 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 EON31841.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EON31841.1 - 0.043 14.2 0.2 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EON31841.1 - 0.044 14.3 0.0 0.095 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON31841.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EON31841.1 - 0.068 12.9 2.8 0.75 9.5 2.8 2.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EON31841.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EON31841.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EON31841.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain VSP PF03302.13 EON31841.1 - 0.28 10.0 1.7 0.48 9.2 1.7 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SbcCD_C PF13558.6 EON31841.1 - 0.82 9.9 3.5 2.2 8.6 0.5 2.9 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit CD99L2 PF12301.8 EON31841.1 - 3.9 7.7 4.3 30 4.9 0.2 2.5 2 0 0 2 2 2 0 CD99 antigen like protein 2 MspA PF09203.11 EON31842.1 - 5.9e-36 124.0 9.5 5.9e-36 124.0 9.5 1.4 2 0 0 2 2 2 1 MspA MspA PF09203.11 EON31843.1 - 5.3e-20 72.0 4.2 1.9e-19 70.2 4.2 2.0 1 1 0 1 1 1 1 MspA MoCF_biosynth PF00994.24 EON31844.1 - 5.6e-22 78.0 0.9 8e-22 77.4 0.9 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Trypsin_2 PF13365.6 EON31845.1 - 2.1e-33 116.3 5.1 6.8e-33 114.7 5.1 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EON31845.1 - 1.3e-18 67.1 1.0 1.3e-18 67.1 1.0 1.9 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 EON31845.1 - 1e-12 48.4 0.7 1.9e-12 47.4 0.7 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 EON31845.1 - 1.5e-07 31.2 0.9 4.3e-07 29.7 0.9 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EON31845.1 - 1.5e-05 25.3 0.1 4.2e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 EON31845.1 - 0.0078 14.9 4.4 0.63 8.6 0.5 2.1 2 0 0 2 2 2 2 Peptidase S46 HATPase_c PF02518.26 EON31846.1 - 6e-20 71.8 0.0 1e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EON31846.1 - 4.1e-13 49.5 1.1 1.3e-12 47.9 1.1 2.0 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 EON31846.1 - 1.4e-10 41.1 0.6 1.4e-10 41.1 0.6 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CCSMST1 PF15013.6 EON31846.1 - 0.04 14.1 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 CCSMST1 family HATPase_c_2 PF13581.6 EON31846.1 - 0.061 13.3 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain DUF4774 PF15999.5 EON31846.1 - 0.81 9.6 4.1 2.2 8.2 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4774) Response_reg PF00072.24 EON31847.1 - 2.9e-32 111.1 0.0 4e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EON31847.1 - 1.6e-27 95.3 0.1 1.3e-26 92.4 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EON31847.1 - 0.0016 18.8 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Molybdopterin PF00384.22 EON31848.1 - 5.8e-76 256.2 0.0 7.9e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EON31848.1 - 1.4e-36 124.9 0.0 2.7e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Flavodoxin_1 PF00258.25 EON31848.1 - 6.8e-29 100.9 0.0 1.4e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EON31848.1 - 3.8e-23 82.2 0.0 7.7e-22 78.0 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EON31848.1 - 9.2e-19 68.1 0.0 1.9e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Molybdop_Fe4S4 PF04879.16 EON31848.1 - 9.2e-15 54.4 0.6 2e-14 53.3 0.6 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain AFG1_ATPase PF03969.16 EON31848.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase GIY-YIG PF01541.24 EON31849.1 - 1.4e-11 44.5 0.0 1.7e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 EON31849.1 - 0.00019 21.9 0.0 0.00024 21.6 0.0 1.1 1 0 0 1 1 1 1 T5orf172 domain Rieske PF00355.26 EON31850.1 - 4.5e-15 55.4 0.0 5.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EON31850.1 - 7.9e-14 51.5 0.0 9.8e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_2 PF07992.14 EON31851.1 - 2.2e-42 145.3 1.0 3.3e-42 144.7 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EON31851.1 - 5.1e-24 84.6 0.0 9.8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EON31851.1 - 2.1e-15 56.3 0.0 5.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.27 EON31851.1 - 9.2e-15 55.0 2.1 2.7e-14 53.5 0.8 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 EON31851.1 - 2.8e-14 52.8 0.0 9e-14 51.1 0.0 2.0 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Fer2_BFD PF04324.15 EON31851.1 - 4.8e-13 49.2 13.3 2.2e-09 37.5 10.7 3.3 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain GIDA PF01134.22 EON31851.1 - 0.0002 20.6 1.3 0.028 13.5 0.6 3.2 2 1 1 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EON31851.1 - 0.00027 20.4 0.4 0.0087 15.4 0.1 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 EON31851.1 - 0.00036 20.2 11.6 0.34 10.4 0.2 3.7 2 2 2 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON31851.1 - 0.0017 17.7 0.0 0.0055 16.0 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON31851.1 - 0.011 15.7 4.3 2.4 8.1 0.1 3.7 2 2 2 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EON31851.1 - 0.016 13.9 0.1 8.6 4.9 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 EON31851.1 - 0.033 14.6 0.3 8.9 6.8 0.2 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EON31851.1 - 0.13 11.0 0.1 0.13 11.0 0.1 2.6 4 0 0 4 4 4 0 Tryptophan halogenase NAD_binding_8 PF13450.6 EON31851.1 - 0.19 12.0 3.0 0.17 12.1 0.7 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EON31851.1 - 0.47 9.7 3.2 0.42 9.9 0.6 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EON31851.1 - 0.79 8.9 3.5 3.5 6.8 2.3 2.1 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EON31853.1 - 1.2e-11 44.3 0.1 1.7e-10 40.6 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 EON31853.1 - 7.9e-11 41.3 19.6 4.9e-09 35.6 6.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EON31853.1 - 1.9e-07 31.5 12.5 3.7e-07 30.6 12.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON31853.1 - 3.6e-06 26.8 6.7 3.6e-06 26.8 6.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 EON31853.1 - 9.7e-06 26.4 8.6 0.0003 21.7 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 EON31853.1 - 1.7e-05 24.6 3.7 1.7e-05 24.6 3.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 EON31853.1 - 2.2e-05 24.5 26.4 0.00025 21.1 2.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EON31853.1 - 9.9e-05 22.4 11.6 0.00019 21.5 11.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 EON31853.1 - 0.00014 22.0 0.1 0.0044 17.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Fer4_21 PF14697.6 EON31853.1 - 0.00022 21.3 14.5 0.0015 18.6 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON31853.1 - 0.00095 19.5 2.3 0.00095 19.5 2.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Pyr_redox PF00070.27 EON31853.1 - 0.0019 18.7 0.1 2.9 8.5 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_8 PF13183.6 EON31853.1 - 0.0037 17.7 0.1 0.0037 17.7 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 EON31853.1 - 0.016 15.2 0.1 0.047 13.7 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fer4_17 PF13534.6 EON31853.1 - 0.039 14.5 0.1 0.039 14.5 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain NAD_binding_7 PF13241.6 EON31853.1 - 0.093 13.2 0.1 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Fer4_3 PF12798.7 EON31853.1 - 0.58 11.2 22.4 0.15 13.1 5.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EON31853.1 - 8.1 7.1 20.0 0.35 11.4 5.7 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I AurF PF11583.8 EON31854.1 - 6.2e-94 314.4 3.5 7.1e-94 314.2 3.5 1.0 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF LppA PF16708.5 EON31854.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium adh_short PF00106.25 EON31855.1 - 3.7e-40 137.5 0.0 4.8e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31855.1 - 8.1e-32 110.6 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31855.1 - 2.3e-06 27.7 0.6 1.2e-05 25.3 0.6 1.9 1 1 0 1 1 1 1 KR domain TPR_14 PF13428.6 EON31856.1 - 0.093 13.6 1.4 4.2 8.4 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0126 PF03458.13 EON31857.1 - 1.4e-38 130.6 27.8 6.7e-20 70.8 8.2 2.2 2 0 0 2 2 2 2 UPF0126 domain TPIP1 PF15338.6 EON31857.1 - 5.5 7.1 6.5 13 5.8 0.2 2.5 3 0 0 3 3 3 0 p53-regulated apoptosis-inducing protein 1 Ribosomal_L32p PF01783.23 EON31858.1 - 1.6e-12 47.4 2.3 1.9e-12 47.3 2.3 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF4190 PF13828.6 EON31859.1 - 7.2e-14 51.3 15.8 9.3e-14 50.9 15.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) DUF3169 PF11368.8 EON31859.1 - 0.45 10.0 3.9 0.5 9.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) IncE PF17627.2 EON31859.1 - 6.9 6.7 7.9 7.6 6.5 7.9 1.1 1 0 0 1 1 1 0 Inclusion membrane protein E FtsX PF02687.21 EON31859.1 - 9.8 6.7 11.5 22 5.6 11.5 1.6 1 1 0 1 1 1 0 FtsX-like permease family DUF4190 PF13828.6 EON31860.1 - 1.2e-13 50.6 16.4 2.1e-13 49.8 16.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) Heliorhodopsin PF18761.1 EON31860.1 - 0.32 10.3 3.6 0.45 9.8 3.6 1.1 1 0 0 1 1 1 0 Heliorhodopsin DUF3007 PF11460.8 EON31860.1 - 1.9 8.8 3.7 2.6 8.4 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3007) T4SS_CagC PF16943.5 EON31860.1 - 7.3 6.8 9.4 2 8.6 3.5 2.0 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system Mem_trans PF03547.18 EON31861.1 - 9.9e-23 80.1 23.8 6.2e-15 54.5 6.7 2.0 2 0 0 2 2 2 2 Membrane transport protein TraL PF07178.11 EON31861.1 - 1.5 9.4 8.8 2.9 8.4 0.1 3.8 3 2 2 5 5 5 0 TraL protein DUF1707 PF08044.11 EON31862.1 - 1.2e-17 63.7 1.5 2.1e-17 62.9 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF2154 PF09922.9 EON31862.1 - 5.6e-05 23.0 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF DUF406 PF04175.12 EON31863.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF406) VWA_2 PF13519.6 EON31864.1 - 1.3e-08 35.5 0.1 1e-06 29.3 0.0 3.4 2 1 0 2 2 2 1 von Willebrand factor type A domain LTXXQ PF07813.12 EON31864.1 - 5.6e-05 23.8 0.4 5.6e-05 23.8 0.4 3.7 4 0 0 4 4 4 1 LTXXQ motif family protein VWA_3 PF13768.6 EON31864.1 - 0.0049 16.8 0.6 0.91 9.4 0.0 4.0 4 1 0 4 4 4 1 von Willebrand factor type A domain VWA PF00092.28 EON31864.1 - 0.02 15.1 0.0 0.4 10.9 0.0 2.5 1 1 0 1 1 1 0 von Willebrand factor type A domain CdiI_2 PF18593.1 EON31864.1 - 0.32 11.7 2.6 0.43 11.3 0.3 2.6 2 0 0 2 2 2 0 CdiI immunity protein Atg14 PF10186.9 EON31864.1 - 0.36 9.9 2.9 1.3 8.0 0.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NifQ PF04891.12 EON31864.1 - 8.4 6.7 6.2 2.3 8.6 1.2 2.5 3 1 0 3 3 3 0 NifQ Mg_chelatase PF01078.21 EON31865.1 - 1.3e-07 31.2 0.1 0.01 15.2 0.0 2.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EON31865.1 - 1.2e-06 28.5 0.1 0.0025 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EON31865.1 - 1.9e-06 27.7 0.0 0.00043 20.0 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 EON31865.1 - 3.6e-05 23.6 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EON31865.1 - 0.00024 20.3 0.0 0.0048 16.0 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain AAA_PrkA PF08298.11 EON31865.1 - 0.00098 18.1 0.0 0.0019 17.2 0.0 1.4 2 0 0 2 2 2 1 PrkA AAA domain ABC_tran PF00005.27 EON31865.1 - 0.056 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TetR_C_16 PF17920.1 EON31865.1 - 0.13 12.5 3.0 0.4 10.9 0.1 3.0 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain MDMPI_N PF11716.8 EON31866.1 - 2.9e-06 28.0 15.3 5.9e-06 27.0 11.8 2.4 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON31866.1 - 0.084 13.4 0.7 0.12 12.9 0.7 1.7 1 1 0 1 1 1 0 DinB superfamily AHSA1 PF08327.11 EON31867.1 - 1.1e-14 54.8 0.0 1.3e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein HTH_20 PF12840.7 EON31868.1 - 3.4e-15 55.8 0.3 5.6e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EON31868.1 - 3.9e-09 36.2 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EON31868.1 - 2.8e-07 30.3 0.7 5.4e-07 29.4 0.7 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EON31868.1 - 5.1e-05 23.1 0.6 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EON31868.1 - 0.0005 20.0 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EON31868.1 - 0.0016 18.3 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EON31868.1 - 0.0026 17.3 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Nup54 PF13874.6 EON31868.1 - 0.0032 17.6 0.2 0.0043 17.2 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 HTH_Crp_2 PF13545.6 EON31868.1 - 0.0033 17.4 0.1 0.014 15.3 0.1 2.1 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 EON31868.1 - 0.0079 15.8 0.8 0.046 13.4 0.0 2.4 2 1 1 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 EON31868.1 - 0.009 15.7 0.1 0.076 12.8 0.0 2.2 1 1 1 2 2 2 1 DeoR-like helix-turn-helix domain RepL PF05732.11 EON31868.1 - 0.0091 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) Rrf2 PF02082.20 EON31868.1 - 0.01 16.2 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_12 PF08461.10 EON31868.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Tropomyosin PF00261.20 EON31868.1 - 0.021 14.2 0.3 0.026 13.9 0.3 1.1 1 0 0 1 1 1 0 Tropomyosin OmdA PF13376.6 EON31868.1 - 0.027 14.5 0.2 1.8 8.6 0.3 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Fe_dep_repress PF01325.19 EON31868.1 - 0.037 14.2 0.2 0.27 11.4 0.2 2.0 1 1 1 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.6 EON31868.1 - 0.043 14.3 0.0 0.081 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.6 EON31868.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TauD PF02668.16 EON31869.1 - 3.2e-58 197.6 0.7 3.7e-58 197.4 0.7 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ABC_tran PF00005.27 EON31871.1 - 1.6e-29 103.2 0.0 2.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31871.1 - 4.8e-07 29.9 0.4 0.0053 16.6 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON31871.1 - 0.00031 21.2 1.4 0.0069 16.8 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON31871.1 - 0.00049 20.0 0.1 0.0016 18.3 0.0 1.8 1 1 1 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EON31871.1 - 0.00096 18.6 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EON31871.1 - 0.00098 18.0 0.2 0.021 13.6 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 EON31871.1 - 0.0051 17.1 0.5 0.013 15.7 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON31871.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EON31871.1 - 0.01 15.4 0.8 0.028 14.0 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EON31871.1 - 0.02 15.2 0.6 0.07 13.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EON31871.1 - 0.033 14.4 0.4 0.42 10.9 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EON31871.1 - 0.034 14.2 0.0 0.045 13.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EON31871.1 - 0.035 14.0 0.4 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EON31871.1 - 0.069 13.3 0.9 0.21 11.7 0.9 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EON31871.1 - 0.074 13.5 0.2 0.37 11.2 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON31871.1 - 0.089 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EON31871.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 EON31871.1 - 0.19 12.2 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EON31871.1 - 0.25 11.0 0.0 0.35 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NMT1 PF09084.11 EON31872.1 - 3.7e-15 56.5 0.0 5.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON31872.1 - 3e-13 50.1 1.0 4.2e-13 49.6 1.0 1.2 1 0 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 EON31872.1 - 8.2e-13 48.5 2.9 1.1e-12 48.0 2.9 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 EON31872.1 - 1.5e-07 31.1 0.7 3.8e-06 26.5 0.2 2.7 1 1 2 3 3 3 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON31872.1 - 2e-07 30.9 1.8 3.4e-07 30.1 1.9 1.3 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 EON31872.1 - 7.1e-05 22.4 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Rotamase_2 PF13145.6 EON31872.1 - 0.015 16.2 0.2 0.035 14.9 0.2 1.6 1 0 0 1 1 1 0 PPIC-type PPIASE domain TetR_C_14 PF17754.1 EON31872.1 - 0.038 13.9 0.8 0.038 13.9 0.8 1.9 2 0 0 2 2 2 0 MftR C-terminal domain BPD_transp_1 PF00528.22 EON31873.1 - 6e-29 101.1 12.2 6e-29 101.1 12.2 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component RHH_1 PF01402.21 EON31873.1 - 0.026 14.4 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Romo1 PF10247.9 EON31873.1 - 0.038 14.4 0.5 0.12 12.7 0.5 1.9 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF222 PF02720.17 EON31875.1 - 1.7e-29 103.2 8.7 2.2e-29 102.9 8.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON31875.1 - 5.4e-09 36.1 11.4 1.2e-08 35.0 11.4 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON31875.1 - 0.045 13.6 5.7 0.087 12.7 5.7 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF3173 PF11372.8 EON31875.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) TauE PF01925.19 EON31876.1 - 1.2e-27 97.1 26.2 1.3e-27 97.0 26.2 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE AICARFT_IMPCHas PF01808.18 EON31877.1 - 1.8e-114 382.2 0.7 2.2e-114 381.9 0.7 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EON31877.1 - 1.3e-23 83.0 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Formyl_trans_N PF00551.19 EON31878.1 - 1.1e-41 142.6 0.0 1.2e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase DUF5336 PF17270.2 EON31880.1 - 9.6e-19 67.6 17.3 9.6e-19 67.6 17.3 4.0 2 2 2 4 4 4 1 Family of unknown function (DUF5336) DUF5357 PF17310.2 EON31880.1 - 0.64 8.5 2.1 0.94 8.0 2.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) AMP-binding PF00501.28 EON31881.1 - 5.3e-46 157.1 0.0 6.9e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON31881.1 - 6.3e-08 33.5 0.8 1.9e-07 31.9 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EON31881.1 - 1.8e-07 30.9 0.5 5.2e-07 29.5 0.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus GHL6 PF14871.6 EON31881.1 - 0.097 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 AMP-binding PF00501.28 EON31882.1 - 1.1e-112 376.8 0.1 1.3e-112 376.5 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON31882.1 - 8.1e-18 65.2 0.0 4.5e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HpcH_HpaI PF03328.14 EON31883.1 - 3.8e-23 81.8 1.3 8e-22 77.5 1.3 2.1 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EON31883.1 - 9.7e-10 38.1 0.1 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold MaoC_dehydratas PF01575.19 EON31884.1 - 3.6e-24 84.7 0.0 4.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON31884.1 - 0.026 14.7 0.0 0.06 13.5 0.0 1.6 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase Acyl-CoA_dh_1 PF00441.24 EON31885.1 - 1.1e-47 162.0 4.8 1.5e-47 161.6 4.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31885.1 - 1.3e-33 116.0 0.0 3.1e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31885.1 - 4.2e-21 74.9 0.3 8e-21 74.1 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON31885.1 - 1.4e-19 70.7 4.1 2.5e-19 69.9 4.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.17 EON31886.1 - 2.9e-76 255.7 0.0 4.9e-76 254.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EON31886.1 - 3.4e-44 149.9 1.5 5.5e-44 149.2 0.7 1.8 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EON31886.1 - 3.6e-34 117.1 0.0 1.5e-33 115.1 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EON31886.1 - 1.4e-17 63.2 4.9 3.8e-17 61.9 4.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EON31886.1 - 1.3e-10 40.9 0.8 0.00057 19.7 0.2 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EON31886.1 - 2.8e-10 40.1 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 EON31886.1 - 0.00023 21.8 7.3 0.15 12.7 0.2 4.2 4 0 0 4 4 4 2 HlyD family secretion protein Peptidase_M23 PF01551.22 EON31886.1 - 0.0006 20.0 0.3 0.0036 17.5 0.1 2.4 2 0 0 2 2 2 1 Peptidase family M23 ATP-grasp_4 PF13535.6 EON31886.1 - 0.01 15.5 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 EON31886.1 - 0.015 15.4 2.7 0.072 13.3 0.0 3.5 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 GCV_H PF01597.19 EON31886.1 - 0.042 13.7 1.7 0.15 11.9 0.7 2.4 2 1 0 2 2 2 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 EON31886.1 - 0.079 12.2 2.5 1.4 8.1 0.1 2.9 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 EON31886.1 - 5.1 7.1 8.9 19 5.3 0.9 4.0 3 1 1 4 4 4 0 RnfC Barrel sandwich hybrid domain Carboxyl_trans PF01039.22 EON31887.1 - 2.3e-145 485.0 0.0 2.8e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EON31887.1 - 0.00027 20.5 0.8 0.26 10.8 0.3 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) POR PF01558.18 EON31888.1 - 9.1e-21 74.7 1.1 1.7e-20 73.8 1.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 EON31888.1 - 7.7e-10 38.8 1.2 1.5e-09 37.8 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF222 PF02720.17 EON31889.1 - 3.7e-10 39.8 0.0 4.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF222) WES_acyltransf PF03007.16 EON31892.1 - 2.7e-06 27.4 1.1 4.9e-06 26.5 1.1 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON31892.1 - 7e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Acyl-CoA_dh_2 PF08028.11 EON31893.1 - 7.7e-15 55.3 2.9 7.7e-15 55.3 2.9 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON31893.1 - 5.4e-09 36.1 0.0 9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON31893.1 - 2e-07 31.3 0.5 3.6e-07 30.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31893.1 - 0.0037 17.9 0.1 0.024 15.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain ECH_1 PF00378.20 EON31895.1 - 2.5e-58 197.4 0.0 3.8e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31895.1 - 4.6e-33 115.1 0.4 4.6e-28 98.7 0.1 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase TLP1_add_C PF18313.1 EON31895.1 - 3.1e-11 43.0 0.0 7.7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 EON31895.1 - 0.031 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Thiolase, C-terminal domain AI-2E_transport PF01594.16 EON31896.1 - 3.6e-50 171.0 31.4 4.8e-50 170.6 31.4 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF2868 PF11067.8 EON31896.1 - 0.3 10.5 6.5 0.094 12.2 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) CPP1-like PF11833.8 EON31896.1 - 6 6.5 12.4 0.17 11.5 4.2 2.5 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Acyl-CoA_dh_1 PF00441.24 EON31897.1 - 3.2e-19 69.6 0.0 9.9e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON31897.1 - 2.3e-18 66.9 0.0 7.5e-18 65.2 0.0 1.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON31897.1 - 6.1e-17 61.6 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 EON31897.1 - 0.00093 18.9 0.1 0.0084 15.8 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 EON31898.1 - 3.9e-24 85.6 3.8 6.1e-24 84.9 3.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON31898.1 - 1.5e-13 50.7 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON31898.1 - 3.5e-08 34.1 0.2 1.1e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON31898.1 - 0.00043 20.6 2.0 0.00043 20.6 2.0 2.2 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PDGLE PF13190.6 EON31898.1 - 0.015 15.2 0.1 1.1 9.3 0.1 2.6 1 1 0 1 1 1 0 PDGLE domain ECH_1 PF00378.20 EON31899.1 - 4.6e-51 173.5 0.0 5.2e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON31899.1 - 1.1e-25 90.9 0.4 1.8e-25 90.2 0.4 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Oxidored_FMN PF00724.20 EON31900.1 - 5.1e-75 252.9 0.0 6e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Bac_luciferase PF00296.20 EON31900.1 - 0.0054 16.2 3.4 1.1 8.6 0.0 2.7 2 1 1 3 3 3 2 Luciferase-like monooxygenase HK PF02110.15 EON31901.1 - 2.1e-57 194.4 1.9 2.4e-57 194.2 1.9 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EON31901.1 - 1.3e-06 28.0 0.1 1.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Bac_luciferase PF00296.20 EON31902.1 - 2.2e-64 217.9 8.5 3.1e-64 217.4 8.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Rhodanese PF00581.20 EON31903.1 - 1.5e-23 83.4 0.0 3e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain FCD PF07729.12 EON31904.1 - 1.6e-15 57.7 16.4 2.3e-15 57.1 16.4 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON31904.1 - 1.2e-12 47.3 1.2 2.4e-12 46.3 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TetR_N PF00440.23 EON31905.1 - 1.6e-10 40.6 0.1 3.6e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family p450 PF00067.22 EON31906.1 - 2.5e-65 221.1 0.0 5.3e-65 220.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Transglycosylas PF06737.14 EON31907.1 - 4e-34 117.1 9.4 5e-34 116.8 9.4 1.1 1 0 0 1 1 1 1 Transglycosylase-like domain RecT PF03837.14 EON31908.1 - 0.074 12.5 0.0 0.096 12.2 0.0 1.1 1 0 0 1 1 1 0 RecT family Peptidase_C92 PF05708.12 EON31910.1 - 0.037 14.1 0.0 1.1 9.4 0.0 2.2 2 1 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family ABC_tran PF00005.27 EON31911.1 - 5.3e-31 108.0 0.0 6.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31911.1 - 5.6e-07 29.7 0.1 0.018 14.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON31911.1 - 0.00033 20.3 0.1 0.00062 19.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON31911.1 - 0.00043 20.9 0.0 0.00069 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 EON31911.1 - 0.002 15.7 0.3 0.0032 15.1 0.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_22 PF13401.6 EON31911.1 - 0.006 16.9 0.3 0.027 14.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON31911.1 - 0.0093 16.4 0.3 0.016 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EON31911.1 - 0.022 14.5 2.7 0.046 13.4 2.7 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EON31911.1 - 0.035 13.6 0.1 0.34 10.3 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 EON31911.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EON31911.1 - 0.036 13.3 0.3 0.055 12.7 0.3 1.4 1 1 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EON31911.1 - 0.054 13.6 0.1 0.078 13.1 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 EON31911.1 - 0.056 12.3 0.1 0.083 11.7 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Zeta_toxin PF06414.12 EON31911.1 - 0.062 12.6 0.1 0.099 11.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ATP-synt_F PF01990.17 EON31911.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit AAA_25 PF13481.6 EON31911.1 - 0.07 12.7 0.1 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EON31911.1 - 0.085 12.5 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EON31911.1 - 0.095 12.6 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 EON31911.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EON31911.1 - 0.15 12.2 0.5 0.33 11.1 0.5 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EON31911.1 - 0.25 10.9 1.0 0.49 10.0 1.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EON31912.1 - 4.6e-24 85.5 0.0 6.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 EON31912.1 - 8.4e-11 41.5 0.3 2.3e-10 40.1 0.3 1.8 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 EON31912.1 - 6e-10 39.4 0.1 3.5e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON31912.1 - 1.3e-06 28.0 0.1 2.6e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON31912.1 - 1.8e-06 28.6 0.1 2.5e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EON31912.1 - 4.3e-06 26.3 0.0 5.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EON31912.1 - 3.2e-05 23.8 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 EON31912.1 - 0.0014 18.2 0.3 0.0034 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EON31912.1 - 0.0038 17.0 0.7 0.0089 15.8 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EON31912.1 - 0.0053 17.2 0.3 0.03 14.8 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON31912.1 - 0.021 15.1 0.2 4.3 7.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON31912.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EON31912.1 - 0.031 14.4 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain 4HBT PF03061.22 EON31912.1 - 0.035 14.5 0.2 0.072 13.5 0.2 1.5 1 0 0 1 1 1 0 Thioesterase superfamily AAA_19 PF13245.6 EON31912.1 - 0.064 13.6 0.3 0.14 12.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EON31912.1 - 0.071 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BPD_transp_2 PF02653.16 EON31913.1 - 7.9e-33 113.7 29.9 1.2e-32 113.2 29.9 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF3851 PF12962.7 EON31913.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Imp-YgjV PF10688.9 EON31913.1 - 0.39 10.5 7.3 0.089 12.6 3.3 2.0 2 0 0 2 2 2 0 Bacterial inner membrane protein BPD_transp_2 PF02653.16 EON31914.1 - 3.9e-50 170.5 37.6 4.5e-50 170.3 37.6 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF2304 PF10066.9 EON31914.1 - 1.7 8.9 0.0 1.7 8.9 0.0 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) Peripla_BP_5 PF13433.6 EON31915.1 - 7.8e-138 459.4 0.5 9.4e-138 459.1 0.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 EON31915.1 - 3.9e-75 253.6 4.9 4.6e-75 253.4 4.9 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EON31915.1 - 3.4e-11 42.8 0.0 3.9e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2236 PF09995.9 EON31917.1 - 1.5e-34 120.2 8.4 2.2e-34 119.6 8.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TetR_N PF00440.23 EON31918.1 - 0.00099 18.9 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_AraC PF00165.23 EON31918.1 - 0.0014 18.7 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Acetyltransf_8 PF13523.6 EON31918.1 - 0.078 12.7 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TetR_C_15 PF17918.1 EON31918.1 - 1.4 9.7 8.7 0.15 12.9 3.9 1.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 EON31919.1 - 9.1e-30 103.8 79.6 1.4e-25 90.0 44.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 EON31919.1 - 7.5e-17 61.0 6.3 2.7e-12 46.0 4.9 2.2 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 BT1 PF03092.16 EON31919.1 - 5.5 5.1 14.1 2.3 6.4 2.9 2.8 2 1 1 3 3 3 0 BT1 family CMD PF02627.20 EON31920.1 - 2.4e-14 53.1 0.8 2.4e-14 53.1 0.8 1.9 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF2339 PF10101.9 EON31922.1 - 2.9e-30 105.5 104.3 4e-17 62.1 83.4 2.1 1 1 1 2 2 2 2 Predicted membrane protein (DUF2339) Form_Nir_trans PF01226.17 EON31923.1 - 7.6e-67 225.1 22.7 8.6e-67 224.9 22.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Trp_oprn_chp PF09534.10 EON31923.1 - 6.4 6.5 15.5 0.47 10.2 5.3 2.2 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cyanate_lyase PF02560.14 EON31924.1 - 1e-32 111.8 0.0 1.4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain PucR PF07905.11 EON31925.1 - 8.6e-31 106.6 0.0 2.3e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 EON31925.1 - 1.1e-15 57.1 0.7 2.4e-15 56.1 0.1 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 EON31925.1 - 0.5 10.4 3.9 1.1 9.2 0.1 3.1 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family dCMP_cyt_deam_1 PF00383.23 EON31926.1 - 4.3e-15 55.4 0.0 5.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EON31926.1 - 2.4e-11 43.5 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EON31926.1 - 0.22 11.6 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DIOX_N PF14226.6 EON31927.1 - 2.2e-20 73.6 0.0 3.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EON31927.1 - 9.3e-14 51.7 0.0 1.8e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ntox37 PF15535.6 EON31927.1 - 0.048 14.1 0.9 0.15 12.5 0.9 1.8 1 0 0 1 1 1 0 Bacterial toxin 37 Rhodanese PF00581.20 EON31928.1 - 4.8e-32 110.7 0.0 3.6e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Glyco_hydro_43 PF04616.14 EON31929.1 - 3.4e-05 23.3 0.8 0.017 14.4 0.5 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Trypsin_2 PF13365.6 EON31931.1 - 5.6e-31 108.5 9.0 5.6e-31 108.5 9.0 2.1 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EON31931.1 - 1.1e-19 70.5 0.4 3.3e-19 69.0 0.4 1.9 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 EON31931.1 - 1.1e-15 58.0 4.3 1.9e-15 57.3 4.3 1.3 1 0 0 1 1 1 1 Trypsin PDZ PF00595.24 EON31931.1 - 1.8e-12 47.4 0.4 1.3e-11 44.7 0.2 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EON31931.1 - 6.8e-11 41.9 1.7 1.2e-10 41.1 0.3 2.1 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EON31931.1 - 0.0031 16.2 4.2 0.024 13.3 0.3 2.1 2 0 0 2 2 2 2 Peptidase S46 Tricorn_PDZ PF14685.6 EON31931.1 - 0.0032 17.4 0.2 0.0096 15.9 0.2 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain Glyoxalase_4 PF13669.6 EON31932.1 - 3.2e-12 46.7 0.0 3.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EON31932.1 - 3.2e-10 40.3 0.0 3.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EON31932.1 - 8.9e-07 29.2 0.1 1.2e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EON31932.1 - 0.064 14.0 0.1 0.084 13.7 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain F420H2_quin_red PF04075.14 EON31933.1 - 8.1e-27 93.9 0.0 1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase PMSR PF01625.21 EON31934.1 - 2e-36 125.4 0.0 2.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase YchF-GTPase_C PF06071.13 EON31935.1 - 2.5e-38 130.1 0.1 2.5e-38 130.1 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EON31935.1 - 5.1e-23 81.3 0.0 1.8e-22 79.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON31935.1 - 1.7e-08 34.1 0.0 4.1e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EON31935.1 - 0.012 15.6 1.5 0.077 13.1 0.4 2.8 2 1 0 2 2 2 0 TGS domain Dynamin_N PF00350.23 EON31935.1 - 0.015 15.3 0.0 0.72 9.9 0.0 2.7 1 1 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EON31935.1 - 0.17 12.5 0.1 0.99 10.0 0.0 2.3 3 1 1 4 4 4 0 AAA domain AI-2E_transport PF01594.16 EON31936.1 - 6.8e-63 212.8 30.1 7.9e-63 212.6 30.1 1.0 1 0 0 1 1 1 1 AI-2E family transporter Ada_Zn_binding PF02805.16 EON31938.1 - 1.2e-28 98.9 9.0 2.3e-28 98.0 9.0 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada AlkA_N PF06029.11 EON31938.1 - 9.2e-26 90.4 0.4 2.6e-25 89.0 0.4 1.8 1 0 0 1 1 1 1 AlkA N-terminal domain HTH_18 PF12833.7 EON31938.1 - 2.1e-19 69.6 1.8 2.1e-19 69.6 1.8 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON31938.1 - 3.9e-10 39.6 0.0 1.6e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HhH-GPD PF00730.25 EON31938.1 - 2.1e-05 24.9 0.1 0.00036 20.9 0.0 2.4 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EON31938.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DNA_binding_1 PF01035.20 EON31939.1 - 8e-22 77.2 0.0 1.6e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RmuC PF02646.16 EON31940.1 - 7.3e-83 278.1 0.0 9.4e-83 277.7 0.0 1.0 1 0 0 1 1 1 1 RmuC family Baculo_PEP_C PF04513.12 EON31940.1 - 0.12 12.4 0.2 4.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PNP_UDP_1 PF01048.20 EON31942.1 - 3.5e-14 52.6 2.9 9.1e-10 38.2 0.1 2.1 1 1 0 2 2 2 2 Phosphorylase superfamily Fructosamin_kin PF03881.14 EON31943.1 - 5.9e-31 107.7 0.0 9.6e-31 107.0 0.0 1.2 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EON31943.1 - 2e-13 50.8 5.2 3.8e-13 49.9 5.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EON31943.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH_6_hur PF04655.14 EON31943.1 - 0.082 12.3 0.7 1.8 7.9 0.1 2.1 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase ABATE PF07336.11 EON31943.1 - 6.1 7.5 14.0 0.41 11.3 8.1 2.0 2 1 0 2 2 2 0 Putative stress-induced transcription regulator adh_short PF00106.25 EON31944.1 - 1.8e-51 174.4 0.1 2.5e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON31944.1 - 1.1e-38 133.1 1.1 1.5e-38 132.7 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON31944.1 - 2.4e-11 43.9 0.8 4e-11 43.1 0.8 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EON31944.1 - 0.0033 16.8 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EON31944.1 - 0.0061 16.1 0.5 0.01 15.3 0.5 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EON31944.1 - 0.061 13.3 1.9 0.12 12.4 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ldh_1_N PF00056.23 EON31944.1 - 0.11 12.6 0.9 0.2 11.8 0.6 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF1541 PF07563.11 EON31944.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Amidase_3 PF01520.18 EON31945.1 - 4.2e-34 118.2 0.0 6.1e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PUL PF08324.11 EON31945.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 PUL domain cobW PF02492.19 EON31946.1 - 1.3e-45 155.1 0.1 1.7e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EON31946.1 - 1.6e-19 69.6 0.0 1.6e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EON31946.1 - 2.9e-05 23.7 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EON31946.1 - 0.00064 20.2 1.5 0.0012 19.3 0.4 2.2 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON31946.1 - 0.0021 18.0 0.2 0.84 9.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EON31946.1 - 0.0025 17.9 0.2 0.0084 16.2 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 EON31946.1 - 0.0027 17.6 0.1 0.0084 16.0 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EON31946.1 - 0.0029 16.7 3.2 0.053 12.5 3.2 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EON31946.1 - 0.0052 17.3 0.2 0.01 16.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON31946.1 - 0.0074 16.5 0.4 0.016 15.3 0.4 1.9 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EON31946.1 - 0.009 15.4 0.2 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family TsaE PF02367.17 EON31946.1 - 0.018 15.1 0.5 0.035 14.1 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EON31946.1 - 0.018 14.3 0.1 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.21 EON31946.1 - 0.033 13.6 1.4 1.6 8.2 0.0 3.0 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_22 PF13401.6 EON31946.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EON31946.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EON31946.1 - 0.075 12.1 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EON31946.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 EON31946.1 - 0.086 12.3 0.3 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EON31946.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF2478 PF10649.9 EON31946.1 - 0.15 11.7 0.8 1.2 8.7 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2478) dNK PF01712.19 EON31946.1 - 0.21 11.4 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase UPF0176_N PF17773.1 EON31947.1 - 5.1e-21 74.8 0.0 7.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 EON31947.1 - 9.2e-10 38.8 1.4 1.1e-09 38.5 0.2 1.7 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 EON31947.1 - 1.3e-06 28.9 0.0 2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Lsm_C PF14894.6 EON31947.1 - 0.007 16.1 0.9 0.03 14.1 0.1 2.1 2 0 0 2 2 2 1 Lsm C-terminal Lsr2 PF11774.8 EON31948.1 - 2.7e-35 120.8 1.6 3e-35 120.7 1.6 1.0 1 0 0 1 1 1 1 Lsr2 DUF4847 PF16139.5 EON31948.1 - 0.0017 18.3 0.1 0.0034 17.3 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4847) HHH_8 PF14716.6 EON31949.1 - 7.6e-12 45.4 0.4 1.5e-11 44.5 0.4 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PHP PF02811.19 EON31949.1 - 2.7e-09 37.6 0.0 3.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 PHP domain HHH_5 PF14520.6 EON31949.1 - 0.0068 17.0 0.3 0.023 15.3 0.3 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EON31949.1 - 0.023 14.6 0.2 0.055 13.4 0.2 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Bac_luciferase PF00296.20 EON31950.1 - 2.4e-82 276.9 10.4 2.7e-82 276.7 10.4 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase SBP_bac_3 PF00497.20 EON31951.1 - 1.3e-11 44.4 0.0 3.1e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON31951.1 - 3.2e-11 43.3 0.3 1.5e-08 34.5 0.1 2.3 1 1 1 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 EON31951.1 - 5.6e-10 39.3 1.0 9.2e-10 38.6 0.4 1.6 2 0 0 2 2 2 1 NMT1-like family NMT1 PF09084.11 EON31951.1 - 6.4e-10 39.3 0.1 1.5e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 EON31951.1 - 1.5e-05 24.6 0.0 0.0018 17.8 0.0 2.1 1 1 1 2 2 2 2 NMT1-like family OpuAC PF04069.12 EON31951.1 - 5.9e-05 22.8 0.4 0.0011 18.6 0.4 2.2 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system DUF4995 PF16386.5 EON31951.1 - 0.026 14.5 0.1 0.063 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function ABC_tran PF00005.27 EON31952.1 - 1.4e-28 100.1 0.0 3.1e-28 99.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EON31952.1 - 1.6e-07 31.7 0.0 4.9e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EON31952.1 - 1.1e-06 28.8 0.8 0.00016 21.6 0.1 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON31952.1 - 4.2e-05 24.0 1.3 6.1e-05 23.5 1.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON31952.1 - 0.00047 20.1 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EON31952.1 - 0.00055 19.6 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EON31952.1 - 0.0013 18.9 0.1 0.0042 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EON31952.1 - 0.0022 18.2 0.3 0.016 15.4 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EON31952.1 - 0.0056 16.7 0.3 0.009 16.1 0.3 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EON31952.1 - 0.0065 16.7 0.3 0.045 14.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON31952.1 - 0.011 15.5 0.6 0.021 14.5 0.5 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EON31952.1 - 0.033 13.6 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EON31952.1 - 0.045 13.7 0.4 0.062 13.2 0.4 1.5 1 1 0 1 1 1 0 NACHT domain ABC_ATPase PF09818.9 EON31952.1 - 0.11 11.2 0.1 5.6 5.6 0.0 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EON31952.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EON31952.1 - 0.13 12.9 0.0 0.5 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EON31952.1 - 0.13 12.7 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EON31952.1 - 0.14 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EON31952.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.6 EON31952.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain BPD_transp_1 PF00528.22 EON31953.1 - 2.1e-26 92.8 13.8 2.1e-26 92.8 13.8 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 EON31953.1 - 0.0059 17.0 0.3 0.019 15.3 0.1 2.0 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 DUF1707 PF08044.11 EON31954.1 - 1.9e-18 66.3 0.2 2.8e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) Beta-lactamase PF00144.24 EON31955.1 - 7.7e-51 173.3 0.1 9.5e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase 4HB PF17947.1 EON31955.1 - 0.1 12.7 0.1 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Four helical bundle domain LigB PF02900.18 EON31956.1 - 3.2e-31 108.4 0.0 3.9e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase RIIa PF02197.17 EON31956.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit AHSA1 PF08327.11 EON31957.1 - 6.3e-18 65.2 0.0 7.3e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EON31957.1 - 0.0036 17.6 1.5 0.015 15.6 1.5 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HTH_20 PF12840.7 EON31958.1 - 1.7e-13 50.4 1.2 2.9e-13 49.6 1.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EON31958.1 - 9.3e-07 28.6 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EON31958.1 - 2.2e-05 24.3 0.7 3.7e-05 23.5 0.7 1.4 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 EON31958.1 - 0.00032 20.8 0.4 0.00032 20.8 0.4 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EON31958.1 - 0.00044 19.8 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EON31958.1 - 0.002 18.0 0.0 0.0064 16.4 0.0 1.8 1 1 1 2 2 2 1 MarR family DprA_WH PF17782.1 EON31958.1 - 0.0048 17.0 0.5 3.5 7.8 0.2 3.1 2 1 0 2 2 2 2 DprA winged helix domain HTH_11 PF08279.12 EON31958.1 - 0.0053 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_45 PF14947.6 EON31958.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Bac_luciferase PF00296.20 EON31959.1 - 6.3e-51 173.7 3.2 8.2e-51 173.3 3.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ABC_tran PF00005.27 EON31960.1 - 1.2e-44 152.2 0.0 7.6e-21 75.1 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EON31960.1 - 3.6e-14 53.3 2.7 0.004 17.0 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON31960.1 - 3.9e-08 33.7 0.1 4.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EON31960.1 - 1e-07 31.6 0.2 0.062 12.7 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON31960.1 - 2.2e-07 31.4 6.3 0.00065 20.1 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EON31960.1 - 2.3e-06 28.2 4.9 0.011 16.2 0.3 2.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EON31960.1 - 3.5e-06 26.7 0.3 0.12 12.2 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON31960.1 - 1.1e-05 25.5 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EON31960.1 - 2.3e-05 24.0 1.4 0.051 13.2 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EON31960.1 - 8e-05 22.6 0.3 0.15 11.9 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 EON31960.1 - 8.4e-05 22.4 6.9 0.031 14.0 0.1 3.1 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EON31960.1 - 0.00017 21.5 0.1 0.87 9.5 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EON31960.1 - 0.00024 21.7 0.4 0.93 10.0 0.2 2.8 2 0 0 2 2 2 2 AAA domain DUF3584 PF12128.8 EON31960.1 - 0.00025 18.7 13.9 0.013 13.0 0.2 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) GTP_EFTU PF00009.27 EON31960.1 - 0.00027 20.6 0.0 0.89 9.1 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain MobB PF03205.14 EON31960.1 - 0.00038 20.4 0.4 1.3 8.9 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EON31960.1 - 0.00042 19.4 1.0 0.29 10.1 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EON31960.1 - 0.0011 19.0 0.2 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EON31960.1 - 0.0012 18.4 5.7 0.68 9.5 1.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EON31960.1 - 0.0015 18.8 6.2 0.12 12.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain NTPase_1 PF03266.15 EON31960.1 - 0.0027 17.7 0.8 0.48 10.3 0.0 2.9 3 0 0 3 3 2 1 NTPase ABC_tran_Xtn PF12848.7 EON31960.1 - 0.0034 17.4 13.7 0.072 13.1 13.7 2.2 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 EON31960.1 - 0.0054 16.0 0.3 0.53 9.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 EON31960.1 - 0.006 15.9 3.4 1 8.6 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin PRK PF00485.18 EON31960.1 - 0.0087 15.8 0.2 2 8.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EON31960.1 - 0.0087 15.8 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EON31960.1 - 0.014 15.6 0.2 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 EON31960.1 - 0.015 14.9 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EON31960.1 - 0.016 14.9 0.4 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EON31960.1 - 0.017 15.2 0.4 6.3 6.9 0.0 2.9 4 0 0 4 4 2 0 AAA domain AAA_13 PF13166.6 EON31960.1 - 0.022 13.4 3.9 2.2 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain TIR-like PF10137.9 EON31960.1 - 0.023 14.6 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain AAA_15 PF13175.6 EON31960.1 - 0.024 14.3 0.2 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EON31960.1 - 0.029 14.8 0.1 5.7 7.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EON31960.1 - 0.033 13.4 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Dynamin_N PF00350.23 EON31960.1 - 0.034 14.2 0.2 5.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.14 EON31960.1 - 0.048 13.7 3.1 11 6.0 0.1 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EON31960.1 - 0.05 13.0 0.2 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EON31960.1 - 0.06 13.5 11.0 0.22 11.7 0.3 3.4 3 2 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 EON31960.1 - 0.083 12.6 0.1 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EON31960.1 - 0.087 13.2 0.0 9 6.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 EON31960.1 - 0.09 11.8 0.6 3.1 6.8 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 EON31960.1 - 0.14 11.8 0.0 9 5.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 EON31960.1 - 0.14 12.2 4.1 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain PduV-EutP PF10662.9 EON31960.1 - 0.31 10.8 0.5 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TetR_C_14 PF17754.1 EON31960.1 - 0.92 9.5 8.3 16 5.5 8.3 2.7 1 1 0 1 1 1 0 MftR C-terminal domain Peptidase_M23 PF01551.22 EON31960.1 - 4.1 7.7 7.1 96 3.3 0.2 4.2 3 2 2 5 5 4 0 Peptidase family M23 Pyr_redox_2 PF07992.14 EON31961.1 - 1.8e-18 66.8 0.0 1.1e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON31961.1 - 9.9e-06 24.9 0.3 1.8e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON31961.1 - 9.5e-05 22.1 1.9 0.0002 21.1 0.2 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON31961.1 - 0.0001 22.8 0.3 0.061 13.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON31961.1 - 0.00024 21.3 0.2 0.0011 19.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EON31961.1 - 0.0019 17.5 0.1 0.0034 16.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EON31961.1 - 0.0032 16.6 0.3 0.0099 15.0 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EON31961.1 - 0.0039 16.4 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EON31961.1 - 0.0052 15.7 0.1 0.0087 15.0 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 EON31961.1 - 0.0076 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EON31961.1 - 0.0085 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON31961.1 - 0.011 15.7 4.5 0.24 11.4 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EON31961.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EON31961.1 - 0.03 13.6 0.3 0.072 12.4 0.2 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EON31961.1 - 0.031 13.6 0.6 0.054 12.8 0.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EON31961.1 - 0.04 12.6 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 EON31961.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF1801 PF08818.11 EON31962.1 - 1.4e-05 25.5 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DU1801) Sigma54_activat PF00158.26 EON31964.1 - 4.2e-09 36.3 0.0 4.9e-05 23.1 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_5 PF07728.14 EON31964.1 - 8.7e-09 35.5 0.0 5e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EON31964.1 - 2.3e-06 27.5 0.0 6.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EON31964.1 - 0.00016 21.1 0.0 0.32 10.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EON31964.1 - 0.00038 20.9 1.5 0.0052 17.2 1.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EON31964.1 - 0.0019 18.6 0.0 0.0065 16.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3618 PF12277.8 EON31964.1 - 0.0089 16.3 0.8 0.036 14.3 0.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) Sigma54_activ_2 PF14532.6 EON31964.1 - 0.023 14.8 0.0 0.069 13.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EON31964.1 - 0.025 14.5 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EON31964.1 - 0.039 13.5 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EON31964.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EON31964.1 - 0.16 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EON31964.1 - 0.23 10.5 0.0 0.43 9.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 EON31964.1 - 0.24 11.1 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_IclR PF09339.10 EON31964.1 - 0.44 10.4 3.9 3.8 7.4 3.9 2.6 1 1 0 1 1 1 0 IclR helix-turn-helix domain TilS PF09179.11 EON31964.1 - 4.3 7.9 7.9 0.37 11.3 0.4 3.0 3 0 0 3 3 3 0 TilS substrate binding domain DUF2201_N PF13203.6 EON31965.1 - 3.1e-27 95.9 3.4 2.3e-25 89.8 3.4 2.1 1 1 0 1 1 1 1 Putative metallopeptidase domain DUF2201 PF09967.9 EON31965.1 - 1.2e-16 61.0 0.0 2.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_2 PF13519.6 EON31965.1 - 0.029 15.0 0.1 0.14 12.8 0.1 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain Glyoxalase PF00903.25 EON31966.1 - 4.4e-08 33.4 0.0 9.8e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON31966.1 - 3.9e-06 27.6 0.1 5.5e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EON31966.1 - 0.00036 20.4 0.0 0.00046 20.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EON31966.1 - 0.00073 19.8 0.0 0.47 10.7 0.0 2.1 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_1 PF00561.20 EON31968.1 - 1.3e-13 51.2 0.0 1.4e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON31968.1 - 1.5e-12 48.6 13.4 2.1e-12 48.1 13.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON31968.1 - 8.1e-10 38.4 0.0 2.6e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EON31968.1 - 0.00027 21.1 0.1 0.00036 20.7 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EON31968.1 - 0.002 17.8 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 EON31968.1 - 0.0051 16.7 0.9 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_4 PF08386.10 EON31968.1 - 0.014 15.4 0.0 0.17 12.0 0.0 2.3 2 1 0 2 2 2 0 TAP-like protein Abhydrolase_5 PF12695.7 EON31968.1 - 0.048 13.4 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family SelB-wing_2 PF09106.11 EON31968.1 - 0.048 13.9 0.1 33 4.8 0.0 3.7 4 1 0 4 4 4 0 Elongation factor SelB, winged helix DLH PF01738.18 EON31968.1 - 0.052 13.1 0.0 8.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 EON31968.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Glyoxalase_6 PF18029.1 EON31969.1 - 5.3e-11 43.3 0.0 6.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EON31969.1 - 6.5e-06 26.4 0.0 2.2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EON31969.1 - 0.031 14.2 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain HTH_20 PF12840.7 EON31970.1 - 2.8e-15 56.1 2.2 2.8e-15 56.1 2.2 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EON31970.1 - 1.4e-12 47.3 0.0 2.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EON31970.1 - 6.7e-09 35.5 1.3 6.7e-09 35.5 1.3 1.8 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EON31970.1 - 1.9e-07 30.9 0.4 3.3e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.16 EON31970.1 - 2.5e-06 26.9 0.1 5.2e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.19 EON31970.1 - 4.7e-06 26.4 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 EON31970.1 - 8.9e-05 22.1 0.1 8.9e-05 22.1 0.1 1.7 2 0 0 2 2 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EON31970.1 - 0.00017 21.5 0.6 0.00028 20.8 0.3 1.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 EON31970.1 - 0.00036 20.1 1.0 0.00082 19.0 0.5 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EON31970.1 - 0.00041 20.6 0.0 0.00073 19.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 EON31970.1 - 0.00093 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 EON31970.1 - 0.0011 19.0 0.2 0.0025 17.9 0.1 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 EON31970.1 - 0.0046 17.4 0.2 0.011 16.3 0.2 1.7 1 1 0 1 1 1 1 Winged helix DNA-binding domain UPF0122 PF04297.14 EON31970.1 - 0.0054 16.9 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_IclR PF09339.10 EON31970.1 - 0.0074 16.1 0.3 0.014 15.2 0.3 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF742 PF05331.11 EON31970.1 - 0.018 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF742) MarR PF01047.22 EON31970.1 - 0.034 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.12 EON31970.1 - 0.035 13.9 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain KfrA_N PF11740.8 EON31970.1 - 0.039 14.6 0.8 0.051 14.2 0.8 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Penicillinase_R PF03965.16 EON31970.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 1 1 2 2 2 0 Penicillinase repressor HTH_40 PF14493.6 EON31970.1 - 0.067 13.7 0.0 0.093 13.2 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.6 EON31970.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) YCII PF03795.14 EON31972.1 - 7.6e-11 42.3 0.0 8.6e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Thioredoxin_4 PF13462.6 EON31973.1 - 8.9e-18 65.0 0.0 1.1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EON31973.1 - 7.1e-06 25.9 0.2 8.3e-05 22.4 0.2 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Haem_degrading PF03928.14 EON31973.1 - 0.0031 17.6 0.2 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Haem-degrading Thioredoxin_2 PF13098.6 EON31973.1 - 0.016 15.7 0.0 0.077 13.5 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain PGM_PMM_I PF02878.16 EON31974.1 - 7.4e-32 109.9 0.0 4.6e-31 107.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EON31974.1 - 3.6e-29 101.3 0.0 6.2e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EON31974.1 - 1.1e-11 45.2 0.1 2.6e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EON31974.1 - 2.9e-09 36.9 0.0 6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Hydrolase_4 PF12146.8 EON31975.1 - 1.4e-07 31.1 0.1 7.6e-07 28.6 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EON31975.1 - 1.1e-06 28.6 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EON31975.1 - 2.5e-05 25.0 12.0 0.00022 21.9 5.2 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON31975.1 - 4.8e-05 23.1 0.0 0.00021 21.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON31975.1 - 5.1e-05 22.8 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EON31975.1 - 0.0043 16.6 0.0 0.006 16.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family PGAP1 PF07819.13 EON31975.1 - 0.033 13.9 0.4 0.052 13.3 0.4 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EON31975.1 - 0.053 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 EON31975.1 - 0.055 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 EON31975.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase AMP-binding PF00501.28 EON31976.1 - 5.5e-62 209.7 0.0 6.6e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON31976.1 - 2.8e-15 57.1 0.6 5.3e-15 56.1 0.6 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.17 EON31977.1 - 3.1e-122 408.3 0.3 3.5e-122 408.1 0.3 1.0 1 0 0 1 1 1 1 CoA-transferase family III ABC_tran PF00005.27 EON31978.1 - 1.2e-26 93.9 0.0 1.7e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31978.1 - 1.5e-13 51.2 2.3 4.4e-07 30.0 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON31978.1 - 0.0034 16.8 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON31978.1 - 0.0042 17.4 0.0 0.021 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EON31978.1 - 0.0056 17.2 0.0 0.008 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON31978.1 - 0.0081 15.9 0.0 0.023 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain KdpD PF02702.17 EON31978.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_29 PF13555.6 EON31978.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EON31978.1 - 0.025 14.3 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 EON31978.1 - 0.036 14.4 0.8 0.09 13.2 0.2 2.0 2 1 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 EON31978.1 - 0.098 12.7 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 EON31978.1 - 0.1 13.0 0.1 0.91 10.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON31978.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EON31978.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 EON31978.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EON31978.1 - 0.18 11.4 0.0 0.65 9.6 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 EON31979.1 - 4.7e-08 32.7 16.8 3.3e-07 29.9 16.8 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EON31979.1 - 0.00027 20.1 13.1 0.00027 20.1 13.1 1.8 1 1 1 2 2 2 2 ABC-2 family transporter protein YqhR PF11085.8 EON31979.1 - 0.017 15.1 3.0 0.017 15.1 3.0 1.7 1 1 0 1 1 1 0 Conserved membrane protein YqhR ABC2_membrane PF01061.24 EON31979.1 - 0.071 12.5 15.6 0.13 11.6 15.6 1.4 1 0 0 1 1 1 0 ABC-2 type transporter CrgA PF06781.12 EON31979.1 - 0.48 10.5 4.8 4.8 7.3 0.0 3.4 2 1 1 3 3 3 0 Cell division protein CrgA Tetraspanin PF00335.20 EON31979.1 - 2.9 7.5 9.3 0.64 9.7 1.3 2.4 2 0 0 2 2 2 0 Tetraspanin family Methyltransf_25 PF13649.6 EON31980.1 - 1.3e-12 48.2 0.0 2.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON31980.1 - 1.3e-09 38.1 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON31980.1 - 8.6e-09 35.9 0.0 1.3e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON31980.1 - 7e-06 26.7 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON31980.1 - 9.6e-05 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON31980.1 - 0.00017 21.1 0.0 0.00049 19.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EON31980.1 - 0.0032 17.5 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EON31980.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Ubie_methyltran PF01209.18 EON31980.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EON31980.1 - 0.09 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EON31980.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EON31980.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EON31980.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 EON31980.1 - 0.16 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EON31980.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ZnuA PF01297.17 EON31981.1 - 1.2e-67 228.0 0.0 1.4e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic TAT_signal PF10518.9 EON31981.1 - 4.4 7.3 8.6 0.41 10.6 3.3 2.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence ABC_tran PF00005.27 EON31982.1 - 8.5e-27 94.3 0.0 1.3e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON31982.1 - 3.4e-09 36.9 1.0 0.00036 20.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON31982.1 - 9.6e-05 21.9 0.1 0.1 12.0 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON31982.1 - 0.002 18.3 0.2 0.05 13.8 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EON31982.1 - 0.0031 17.2 0.9 0.0068 16.1 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON31982.1 - 0.0065 16.6 0.4 0.016 15.3 0.1 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EON31982.1 - 0.0097 15.1 0.4 0.015 14.5 0.4 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EON31982.1 - 0.022 14.5 1.4 0.042 13.6 1.4 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON31982.1 - 0.031 14.2 0.4 0.058 13.3 0.2 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EON31982.1 - 0.032 14.4 0.9 0.1 12.7 0.9 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EON31982.1 - 0.077 13.5 0.8 0.12 12.8 0.8 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON31982.1 - 0.088 12.4 0.4 0.22 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EON31982.1 - 0.11 12.9 0.8 0.87 10.0 0.8 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EON31982.1 - 0.29 11.5 2.5 0.9 9.9 2.5 2.0 1 1 0 1 1 1 0 AAA ATPase domain ABC-3 PF00950.17 EON31983.1 - 7.9e-80 268.1 31.5 9e-80 267.9 31.5 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 EON31983.1 - 4.8e-08 32.4 28.4 4.8e-08 32.4 28.4 1.8 1 1 1 2 2 2 1 FecCD transport family Nramp PF01566.18 EON31983.1 - 0.00089 18.3 12.1 0.00089 18.3 12.1 2.5 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Hairy_orange PF07527.13 EON31985.1 - 0.2 11.9 0.3 0.7 10.1 0.2 1.9 3 0 0 3 3 3 0 Hairy Orange AbiEi_4 PF13338.6 EON31989.1 - 0.015 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin MFS_1 PF07690.16 EON31990.1 - 1.3e-41 142.7 64.5 2e-35 122.4 46.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON31990.1 - 3.5e-15 55.8 11.6 3.5e-15 55.8 11.6 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 EON31990.1 - 0.41 9.9 44.1 0.53 9.5 44.1 1.2 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Ribonuc_L-PSP PF01042.21 EON31991.1 - 4.4e-17 62.2 0.0 5.3e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rieske PF00355.26 EON31993.1 - 2.4e-14 53.1 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Aromatic_hydrox PF11723.8 EON31993.1 - 0.0089 15.5 0.1 0.24 10.8 0.0 2.1 2 0 0 2 2 2 2 Homotrimeric ring hydroxylase Abhydrolase_4 PF08386.10 EON31995.1 - 0.056 13.6 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein TPP_enzyme_N PF02776.18 EON31996.1 - 8.6e-42 142.7 7.8 1.3e-39 135.6 1.5 2.8 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON31996.1 - 2e-30 105.3 0.1 3.5e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EON31996.1 - 5.1e-23 81.6 0.1 3.1e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short_C2 PF13561.6 EON31997.1 - 5.4e-46 157.0 3.9 6.3e-46 156.8 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31997.1 - 6.4e-42 143.2 0.2 7.4e-42 143.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31997.1 - 5e-15 55.9 2.5 1.4e-14 54.4 0.6 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EON31997.1 - 0.022 14.2 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EON31997.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 EON31998.1 - 2.3e-57 194.3 1.7 2.7e-57 194.0 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON31998.1 - 2.6e-45 154.3 0.1 3e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON31998.1 - 1.5e-14 54.3 0.6 2e-14 53.9 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON31998.1 - 0.0041 16.6 0.9 0.0091 15.5 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EON31998.1 - 0.055 13.7 0.4 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 TrkA-N domain AdoHcyase_NAD PF00670.21 EON31998.1 - 0.18 11.9 1.4 1.9 8.6 1.2 2.1 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Abhydrolase_1 PF00561.20 EON31999.1 - 1.9e-22 80.2 0.1 6.8e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON31999.1 - 6.4e-21 74.7 0.0 1.7e-20 73.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON31999.1 - 9.1e-21 75.5 14.9 1.1e-20 75.2 14.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON31999.1 - 2.8e-08 34.1 0.0 1.5e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 EON31999.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 EON31999.1 - 0.0087 15.6 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EON31999.1 - 0.0092 15.5 0.0 11 5.5 0.0 3.3 1 1 3 4 4 4 1 Dienelactone hydrolase family Esterase PF00756.20 EON31999.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.13 EON31999.1 - 0.022 14.6 0.6 0.046 13.6 0.6 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EON31999.1 - 0.041 13.7 0.1 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 EON31999.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Glyoxalase PF00903.25 EON32000.1 - 1.1e-25 90.3 0.0 2.9e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON32000.1 - 2.6e-07 31.4 0.4 0.029 15.2 0.2 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EON32000.1 - 0.0015 18.7 0.1 0.08 13.2 0.1 2.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_C PF14507.6 EON32000.1 - 0.097 13.4 0.0 7.9 7.3 0.0 2.2 2 0 0 2 2 2 0 CppA C-terminal Fer2 PF00111.27 EON32001.1 - 2.2e-14 53.1 0.9 4.4e-14 52.2 0.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON32001.1 - 5.7e-06 26.9 0.0 5.9e-05 23.7 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON32001.1 - 0.00027 21.3 0.0 0.00049 20.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.6 EON32001.1 - 0.0004 20.4 0.1 0.00091 19.2 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 EON32001.1 - 0.018 15.2 0.2 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Cupin_2 PF07883.11 EON32002.1 - 4e-14 52.1 0.2 7.7e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EON32002.1 - 4e-08 33.0 0.0 5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 EON32002.1 - 0.0005 20.2 0.0 0.0017 18.5 0.0 1.8 1 1 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.12 EON32002.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_7 PF12973.7 EON32002.1 - 0.011 15.6 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain FdtA PF05523.11 EON32002.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal Pirin PF02678.16 EON32002.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Pirin cNMP_binding PF00027.29 EON32002.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Ribonuc_L-PSP PF01042.21 EON32003.1 - 1.5e-23 83.1 0.3 1.9e-23 82.8 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CBP_BcsQ PF06564.12 EON32003.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Aldedh PF00171.22 EON32004.1 - 1.5e-159 531.5 0.0 1.7e-159 531.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BMC PF00936.19 EON32004.1 - 0.14 12.2 1.2 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 BMC domain MarR PF01047.22 EON32005.1 - 3.4e-10 39.7 0.0 6.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON32005.1 - 1.8e-09 37.3 3.3 2.1e-09 37.1 0.8 2.2 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EON32005.1 - 2.7e-07 31.0 0.4 9.9e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EON32005.1 - 3e-06 26.7 0.0 5.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 EON32005.1 - 1.3e-05 25.2 0.0 2.9e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 EON32005.1 - 0.00011 22.2 2.3 0.00035 20.6 0.3 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 EON32005.1 - 0.067 13.0 0.2 0.067 13.0 0.2 2.2 2 1 0 2 2 2 0 IclR helix-turn-helix domain HxlR PF01638.17 EON32005.1 - 0.068 13.0 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix TrmB PF01978.19 EON32005.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EON32005.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain PadR PF03551.14 EON32005.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_AsnC-type PF13404.6 EON32005.1 - 0.46 10.4 3.1 0.81 9.6 0.4 2.6 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain Abhydrolase_1 PF00561.20 EON32006.1 - 6.9e-22 78.3 0.1 8.6e-20 71.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON32006.1 - 3.2e-19 70.4 0.4 3.8e-19 70.2 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON32006.1 - 2.1e-10 40.3 0.0 3.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EON32006.1 - 0.0064 16.4 0.0 0.075 13.0 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EON32006.1 - 0.012 15.1 0.1 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 EON32006.1 - 0.029 14.0 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase HTH_20 PF12840.7 EON32007.1 - 1.5e-09 37.8 0.3 2.2e-09 37.2 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EON32007.1 - 3.3e-08 33.3 0.4 6.1e-08 32.4 0.1 1.5 2 0 0 2 2 1 1 MarR family HTH_24 PF13412.6 EON32007.1 - 7.1e-07 28.7 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EON32007.1 - 2.9e-05 24.4 0.1 5.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 EON32007.1 - 9.2e-05 22.3 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 EON32007.1 - 0.00017 21.4 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 EON32007.1 - 0.00035 20.9 0.0 0.00052 20.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 EON32007.1 - 0.00035 20.4 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 EON32007.1 - 0.00055 20.1 0.0 0.00087 19.4 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain PaaX PF07848.12 EON32007.1 - 0.0008 19.6 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 PaaX-like protein HTH_Crp_2 PF13545.6 EON32007.1 - 0.0076 16.2 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EON32007.1 - 0.015 15.1 0.3 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_11 PF08279.12 EON32007.1 - 0.019 14.9 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 HTH domain DUF4423 PF14394.6 EON32007.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Penicillinase_R PF03965.16 EON32007.1 - 0.023 15.1 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor GntR PF00392.21 EON32007.1 - 0.062 13.0 0.5 0.23 11.1 0.2 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_Tnp_1 PF01527.20 EON32007.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_39 PF14090.6 EON32007.1 - 0.089 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EON32007.1 - 0.11 12.3 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_10 PF04967.12 EON32007.1 - 0.13 12.0 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_36 PF13730.6 EON32007.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SBP_bac_5 PF00496.22 EON32008.1 - 1.4e-65 221.7 0.2 1.7e-65 221.5 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EON32009.1 - 7.1e-29 100.9 15.3 2.3e-28 99.2 13.0 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EON32010.1 - 1.9e-15 57.1 12.1 1.9e-15 57.1 12.1 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EON32011.1 - 1.3e-19 71.0 0.0 1.8e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32011.1 - 3.4e-11 43.5 0.0 3.4e-09 36.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON32011.1 - 9.8e-05 21.9 0.0 0.083 12.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON32011.1 - 0.0014 18.9 0.2 0.019 15.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EON32011.1 - 0.0027 17.1 0.9 0.011 15.1 0.5 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EON32011.1 - 0.0079 15.8 0.8 0.063 12.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EON32011.1 - 0.039 14.0 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EON32011.1 - 0.045 13.5 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON32011.1 - 0.084 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EON32011.1 - 0.088 13.2 2.0 0.37 11.2 2.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EON32011.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EON32011.1 - 0.17 11.8 0.0 0.68 9.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EON32012.1 - 4.4e-23 82.3 0.0 5.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32012.1 - 1.8e-10 41.2 0.0 5.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EON32012.1 - 0.01 15.6 1.6 0.038 13.7 1.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON32012.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON32012.1 - 0.018 14.8 0.3 0.032 14.0 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON32012.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 EON32012.1 - 0.065 12.8 0.4 0.099 12.2 0.4 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EON32012.1 - 0.067 12.6 0.1 5.6 6.3 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EON32012.1 - 0.073 13.0 0.6 0.13 12.2 0.2 1.6 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 EON32012.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 EON32012.1 - 0.12 12.8 0.1 0.16 12.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EON32012.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EON32012.1 - 0.19 12.1 2.6 0.42 11.0 2.6 1.7 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EON32012.1 - 0.23 10.6 0.5 0.32 10.1 0.5 1.1 1 0 0 1 1 1 0 NB-ARC domain PIR PF00399.19 EON32012.1 - 0.35 10.5 1.7 0.64 9.7 1.7 1.4 1 0 0 1 1 1 0 Yeast PIR protein repeat Ribonuc_red_sm PF00268.21 EON32013.1 - 2.8e-13 49.9 0.0 5.6e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain Rubrerythrin PF02915.17 EON32013.1 - 0.012 16.0 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 Rubrerythrin ADH_N PF08240.12 EON32014.1 - 2.8e-27 94.7 1.0 6.9e-27 93.5 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON32014.1 - 1e-22 80.5 0.9 1.9e-22 79.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EON32014.1 - 0.002 17.5 0.3 0.0044 16.4 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EON32014.1 - 0.0048 17.9 0.0 0.0077 17.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON32014.1 - 0.041 13.4 1.1 0.077 12.5 1.1 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AdoHcyase_NAD PF00670.21 EON32014.1 - 0.37 10.8 7.7 0.67 10.0 2.8 2.7 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EON32014.1 - 1.1 8.6 8.3 1.5 8.0 7.2 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ion_trans_2 PF07885.16 EON32015.1 - 1e-12 47.8 3.7 1e-12 47.8 3.7 1.9 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 EON32015.1 - 0.0033 17.3 3.4 0.029 14.2 3.4 2.0 1 1 1 2 2 2 1 Ligand-gated ion channel DUF4199 PF13858.6 EON32015.1 - 0.0066 16.9 3.5 0.011 16.1 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Ion_trans PF00520.31 EON32015.1 - 0.043 13.0 3.8 0.061 12.6 3.8 1.3 1 0 0 1 1 1 0 Ion transport protein Wzy_C PF04932.15 EON32015.1 - 0.053 13.1 2.1 0.075 12.7 2.1 1.3 1 0 0 1 1 1 0 O-Antigen ligase DUF2976 PF11190.8 EON32015.1 - 0.51 10.2 2.8 1 9.2 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) PEP-CTERM PF07589.11 EON32015.1 - 1.1 9.4 5.3 4.8 7.4 0.2 3.2 3 0 0 3 3 3 0 PEP-CTERM motif Peptidase_M13_N PF05649.13 EON32016.1 - 1.5e-102 344.2 0.0 1.9e-102 343.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EON32016.1 - 1.6e-75 253.2 0.0 2.5e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 EON32016.1 - 0.0033 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Pyr_redox_2 PF07992.14 EON32017.1 - 3.8e-43 147.8 2.9 3.8e-43 147.8 2.9 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EON32017.1 - 1.7e-22 79.7 0.0 4.5e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EON32017.1 - 4.2e-13 49.6 1.4 2.1e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EON32017.1 - 0.0023 18.3 0.3 1.4 9.4 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding GIDA PF01134.22 EON32017.1 - 0.0034 16.5 6.4 0.011 14.8 0.7 3.4 4 0 0 4 4 4 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EON32017.1 - 0.014 14.7 4.7 0.071 12.4 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EON32017.1 - 0.015 14.5 0.0 0.064 12.4 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EON32017.1 - 0.021 14.1 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Putative_PNPOx PF01243.20 EON32018.1 - 1.8e-11 44.0 0.0 3.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EON32018.1 - 5.4e-06 26.1 0.0 6.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like MannoseP_isomer PF01050.18 EON32018.1 - 0.0041 17.0 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase PqqD PF05402.12 EON32018.1 - 0.16 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Herpes_UL49_2 PF04823.12 EON32018.1 - 0.16 12.1 0.7 0.31 11.2 0.2 1.7 1 1 1 2 2 2 0 Herpesvirus UL49 tegument protein GntR PF00392.21 EON32019.1 - 6.6e-19 67.3 0.9 1.5e-18 66.2 0.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EON32019.1 - 8.8e-18 64.9 2.7 8.8e-18 64.9 2.7 2.2 2 0 0 2 2 2 1 FCD domain HTH_Crp_2 PF13545.6 EON32019.1 - 1.6e-05 24.8 0.2 4.7e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EON32019.1 - 5.3e-05 23.0 7.3 8.5e-05 22.4 0.6 3.7 3 1 1 4 4 4 1 MarR family HTH_29 PF13551.6 EON32019.1 - 6.9e-05 22.8 0.1 0.00029 20.8 0.1 2.0 1 1 1 2 2 2 1 Winged helix-turn helix Fe_dep_repress PF01325.19 EON32019.1 - 8.3e-05 22.7 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 EON32019.1 - 0.00027 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 EON32019.1 - 0.0003 20.5 1.5 0.0012 18.5 0.1 2.5 2 1 1 3 3 2 1 Homeodomain-like domain HTH_24 PF13412.6 EON32019.1 - 0.00036 20.0 0.1 0.00069 19.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 EON32019.1 - 0.00097 19.2 2.6 0.0053 16.9 0.1 2.8 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_5 PF01022.20 EON32019.1 - 0.0024 17.7 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_36 PF13730.6 EON32019.1 - 0.003 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EON32019.1 - 0.0076 16.2 0.1 0.05 13.6 0.1 2.1 2 0 0 2 2 2 1 HTH domain RP-C PF03428.13 EON32019.1 - 0.0076 15.9 0.3 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Replication protein C N-terminal domain HTH_AsnC-type PF13404.6 EON32019.1 - 0.011 15.6 0.6 0.028 14.2 0.6 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PaaX PF07848.12 EON32019.1 - 0.019 15.1 0.2 0.043 14.0 0.2 1.6 1 0 0 1 1 1 0 PaaX-like protein MarR PF01047.22 EON32019.1 - 0.025 14.5 0.0 0.088 12.7 0.0 1.9 1 1 1 2 2 2 0 MarR family HTH_17 PF12728.7 EON32019.1 - 0.025 14.7 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 EON32019.1 - 0.026 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain HTH_8 PF02954.19 EON32019.1 - 0.041 13.7 0.2 0.041 13.7 0.2 1.9 2 0 0 2 2 1 0 Bacterial regulatory protein, Fis family HTH_41 PF14502.6 EON32019.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EON32019.1 - 0.049 13.3 0.7 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 YdaS_antitoxin PF15943.5 EON32019.1 - 0.05 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Rrf2 PF02082.20 EON32019.1 - 0.063 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Sigma70_r3 PF04539.16 EON32019.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 NUMOD1 PF07453.13 EON32019.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 1 0 NUMOD1 domain HTH_20 PF12840.7 EON32019.1 - 0.12 12.4 3.8 0.27 11.3 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 EON32019.1 - 0.21 11.4 0.2 0.21 11.4 0.2 3.2 3 1 1 4 4 4 0 IclR helix-turn-helix domain FA_hydroxylase PF04116.13 EON32020.1 - 1.6e-17 64.1 10.1 1.6e-17 64.1 10.1 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NAD_binding_10 PF13460.6 EON32021.1 - 7.5e-16 58.5 5.9 2.4e-15 56.9 4.7 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EON32021.1 - 1e-15 57.9 0.3 1.9e-15 57.0 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON32021.1 - 6.9e-11 42.1 0.4 1.3e-10 41.3 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EON32021.1 - 5.2e-06 25.7 0.0 8.3e-06 25.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EON32021.1 - 1.1e-05 25.1 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 EON32021.1 - 0.00061 19.5 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 EON32021.1 - 0.0033 16.5 0.3 0.0038 16.4 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EON32021.1 - 0.015 14.7 0.5 0.027 13.9 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Amidase PF01425.21 EON32022.1 - 5.6e-69 233.2 4.4 9.5e-69 232.5 4.4 1.3 1 0 0 1 1 1 1 Amidase Abhydrolase_6 PF12697.7 EON32023.1 - 0.0052 17.4 12.4 0.018 15.7 12.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Isochorismatase PF00857.20 EON32024.1 - 2.4e-42 145.1 0.0 3.2e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Amido_AtzD_TrzD PF09663.10 EON32025.1 - 9.5e-112 373.6 5.9 1.2e-111 373.3 5.9 1.1 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Xan_ur_permease PF00860.20 EON32026.1 - 1.5e-86 290.5 42.3 2.1e-86 290.1 42.3 1.1 1 0 0 1 1 1 1 Permease family GntR PF00392.21 EON32027.1 - 1.6e-18 66.1 0.0 2.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EON32027.1 - 1.1e-17 64.6 2.8 1.7e-17 64.0 2.8 1.3 1 0 0 1 1 1 1 FCD domain Fe_dep_repress PF01325.19 EON32027.1 - 0.00023 21.3 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 EON32027.1 - 0.0096 15.8 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 EON32027.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_41 PF14502.6 EON32027.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EON32027.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 EON32027.1 - 0.12 12.0 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EON32027.1 - 0.19 11.6 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Pirin PF02678.16 EON32028.1 - 3.8e-29 100.8 0.1 6e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EON32028.1 - 3.2e-05 23.6 4.7 0.0033 17.1 0.4 3.0 2 1 1 3 3 3 2 Cupin domain Pirin_C_2 PF17954.1 EON32028.1 - 6.9e-05 22.9 0.0 0.00019 21.6 0.0 1.7 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain MecA_N PF05223.11 EON32029.1 - 7.2e-10 39.2 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain DUF3054 PF11255.8 EON32030.1 - 4.6e-32 110.8 13.5 5.8e-32 110.5 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) MbtH PF03621.13 EON32030.1 - 0.18 11.3 0.2 2 7.9 0.1 2.2 2 0 0 2 2 2 0 MbtH-like protein EMP70 PF02990.16 EON32030.1 - 0.69 8.5 4.3 0.9 8.1 4.3 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4191 PF13829.6 EON32030.1 - 4.7 6.5 6.1 1 8.7 2.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) LPG_synthase_TM PF03706.13 EON32031.1 - 4.4e-36 124.9 30.8 5.7e-36 124.6 30.8 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region La_HTH_kDCL PF18177.1 EON32031.1 - 0.093 13.0 0.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain AI-2E_transport PF01594.16 EON32032.1 - 3e-60 204.1 25.5 3.4e-60 203.9 25.5 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF3368 PF11848.8 EON32032.1 - 0.13 12.0 1.3 0.41 10.5 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) NDUF_B12 PF08122.12 EON32032.1 - 2.5 8.2 4.7 24 5.1 0.4 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family HATPase_c PF02518.26 EON32033.1 - 1.9e-10 41.2 0.1 3.7e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 EON32033.1 - 0.00027 21.4 2.1 0.00027 21.4 2.1 2.6 2 1 0 2 2 2 1 Histidine kinase HATPase_c_2 PF13581.6 EON32033.1 - 0.0013 18.6 1.1 0.0035 17.3 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain 5TM-5TMR_LYT PF07694.12 EON32033.1 - 0.0047 16.4 3.2 0.0047 16.4 3.2 1.8 2 0 0 2 2 2 1 5TMR of 5TMR-LYT Response_reg PF00072.24 EON32034.1 - 6.9e-24 84.2 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON32034.1 - 6.4e-21 73.7 0.2 5.6e-20 70.7 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON32034.1 - 3.4e-08 33.0 1.1 2.3e-07 30.4 0.4 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 EON32034.1 - 6.6e-07 28.9 0.4 1.3e-05 24.8 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 EON32034.1 - 2.1e-05 24.2 1.3 5.2e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EON32034.1 - 4.6e-05 22.9 1.4 9.8e-05 21.8 1.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 EON32034.1 - 5.8e-05 23.1 0.1 0.0011 19.1 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 EON32034.1 - 0.00014 22.2 0.1 0.00046 20.6 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 EON32034.1 - 0.00015 21.7 0.1 0.0012 18.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_20 PF12840.7 EON32034.1 - 0.00018 21.5 0.3 0.00047 20.2 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EON32034.1 - 0.00044 20.1 0.9 0.001 18.9 0.3 1.9 2 0 0 2 2 2 1 HTH domain HTH_7 PF02796.15 EON32034.1 - 0.001 19.1 0.1 0.0027 17.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 EON32034.1 - 0.0031 16.9 0.1 0.0093 15.4 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 EON32034.1 - 0.0089 15.8 1.7 0.19 11.5 1.7 2.6 1 1 0 1 1 1 1 HTH DNA binding domain Sigma70_ECF PF07638.11 EON32034.1 - 0.013 15.4 0.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 ECF sigma factor DUF746 PF05344.11 EON32034.1 - 0.025 14.4 0.2 0.076 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) DUF2802 PF10975.8 EON32034.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) HTH_24 PF13412.6 EON32034.1 - 0.042 13.4 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Terminase_5 PF06056.12 EON32034.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MarR_2 PF12802.7 EON32034.1 - 0.091 12.7 1.5 0.21 11.5 0.2 2.2 2 0 0 2 2 2 0 MarR family HU-CCDC81_euk_2 PF18289.1 EON32034.1 - 0.11 12.7 0.0 0.75 10.0 0.0 2.1 1 1 1 2 2 2 0 CCDC81 eukaryotic HU domain 2 Glycos_transf_1 PF00534.20 EON32034.1 - 0.16 11.5 0.1 1.3 8.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF4510 PF14971.6 EON32034.1 - 0.22 11.9 3.0 0.42 10.9 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) MMPL PF03176.15 EON32035.1 - 4.5e-75 252.7 23.3 6.2e-44 150.3 4.1 2.4 2 1 0 2 2 2 2 MMPL family DUF1772 PF08592.11 EON32035.1 - 0.0095 16.3 4.5 0.0095 16.3 4.5 3.4 2 2 0 2 2 2 1 Domain of unknown function (DUF1772) Methyltransf_4 PF02390.17 EON32037.1 - 8.7e-47 158.8 0.0 1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EON32037.1 - 0.0001 22.1 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 EON32037.1 - 0.00014 21.1 0.0 0.00018 20.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.6 EON32037.1 - 0.00049 20.7 0.0 0.00085 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32037.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 EON32037.1 - 0.0043 18.0 0.0 0.01 16.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EON32037.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 EON32037.1 - 0.018 14.9 0.0 0.1 12.4 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 EON32037.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_11 PF08241.12 EON32037.1 - 0.045 14.4 0.0 0.092 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EON32037.1 - 0.086 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 EON32037.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EON32037.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain DUF4191 PF13829.6 EON32039.1 - 0.15 11.4 1.4 0.68 9.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) EF-hand_1 PF00036.32 EON32040.1 - 0.86 9.3 2.9 26 4.7 0.1 2.7 2 0 0 2 2 2 0 EF hand PEPCK_GTP PF00821.18 EON32041.1 - 3.4e-171 568.9 0.0 4.1e-171 568.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 EON32041.1 - 8e-102 339.5 0.0 1e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Phytase-like PF13449.6 EON32042.1 - 2.8e-27 96.4 0.0 3.7e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Esterase-like activity of phytase ABC_tran PF00005.27 EON32043.1 - 2.8e-30 105.6 0.0 4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON32043.1 - 4e-07 29.7 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON32043.1 - 2e-05 24.2 0.1 3.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EON32043.1 - 4e-05 23.6 0.0 0.019 14.8 0.0 2.7 1 1 2 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON32043.1 - 0.0003 21.4 0.0 0.00044 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON32043.1 - 0.00033 20.3 0.1 0.0046 16.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EON32043.1 - 0.00086 19.2 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EON32043.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EON32043.1 - 0.0047 16.7 0.1 0.013 15.2 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON32043.1 - 0.0075 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EON32043.1 - 0.025 14.3 0.0 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 EON32043.1 - 0.034 14.6 0.0 0.61 10.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EON32043.1 - 0.059 13.5 0.1 0.15 12.2 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EON32043.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain CLP1_P PF16575.5 EON32043.1 - 0.072 12.9 0.1 0.75 9.6 0.1 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 EON32043.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EON32043.1 - 0.16 10.6 0.0 3.5 6.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EON32043.1 - 0.21 11.3 0.7 0.36 10.5 0.2 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 EON32043.1 - 0.22 11.7 0.6 0.52 10.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain FtsX PF02687.21 EON32044.1 - 1.9e-25 89.1 14.2 2.7e-14 53.4 6.1 6.5 6 1 0 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 EON32044.1 - 3.2e-14 53.7 20.0 3.9e-09 37.1 6.2 5.7 5 2 1 6 6 6 2 MacB-like periplasmic core domain DUF4134 PF13572.6 EON32044.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4134) Epiglycanin_C PF14654.6 EON32044.1 - 0.21 11.7 3.4 0.24 11.5 0.4 2.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Mucin PF01456.17 EON32045.1 - 0.00048 20.1 13.8 0.0007 19.6 13.8 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.11 EON32045.1 - 0.0016 16.8 15.7 0.002 16.4 15.7 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF3357 PF11837.8 EON32045.1 - 0.0025 18.3 0.1 0.0045 17.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF4834 PF16118.5 EON32045.1 - 0.056 14.4 0.1 0.093 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 EON32045.1 - 0.074 13.3 0.1 0.074 13.3 0.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EON32045.1 - 3.2 8.7 0.0 3.2 8.7 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MTES_1575 PF18741.1 EON32046.1 - 1.6e-09 37.8 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 EON32046.1 - 7.2e-09 35.5 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) Methyltransf_11 PF08241.12 EON32047.1 - 3.1e-15 56.6 0.0 5.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32047.1 - 5.2e-10 39.9 0.0 1.1e-09 38.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32047.1 - 6.5e-09 35.8 0.0 9.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32047.1 - 1.6e-06 28.8 0.0 3.4e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32047.1 - 4.9e-05 23.2 0.0 0.0042 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON32047.1 - 0.012 14.9 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M66 PF10462.9 EON32047.1 - 1.5 7.7 4.4 0.31 10.0 1.1 1.4 2 0 0 2 2 2 0 Peptidase M66 Glycos_transf_1 PF00534.20 EON32048.1 - 2.3e-28 98.9 0.0 3.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON32048.1 - 7.9e-21 74.9 0.0 1.7e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON32048.1 - 1.6e-19 70.5 1.0 1.6e-19 70.5 1.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON32048.1 - 1.6e-15 57.9 9.1 1.6e-15 57.9 9.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EON32048.1 - 1.3e-09 38.3 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PhnG PF06754.12 EON32048.1 - 0.086 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG HpcH_HpaI PF03328.14 EON32050.1 - 2.2e-27 95.7 0.0 3.9e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EON32050.1 - 0.016 14.4 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold Polyketide_cyc2 PF10604.9 EON32052.1 - 8.2e-06 26.1 0.4 9.6e-06 25.9 0.4 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EON32052.1 - 7.4e-05 23.0 0.2 9.4e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein PorA PF11271.8 EON32053.1 - 7.2e-76 255.4 2.6 8.3e-76 255.1 2.6 1.0 1 0 0 1 1 1 1 Porin PorA Acyl_transf_3 PF01757.22 EON32054.1 - 2.5e-25 89.2 29.6 3.7e-25 88.7 29.6 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF3367 PF11847.8 EON32055.1 - 5.2e-262 870.6 22.6 5.2e-262 870.6 22.6 2.7 2 1 1 3 3 3 1 Alpha-(1->3)-arabinofuranosyltransferase F5_F8_type_C PF00754.25 EON32055.1 - 8e-06 26.0 0.4 0.14 12.2 0.1 3.5 2 1 0 2 2 2 2 F5/8 type C domain DUF63 PF01889.17 EON32055.1 - 0.21 11.8 0.1 0.39 10.9 0.1 1.4 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 DUF2613 PF11021.8 EON32056.1 - 7.5e-15 54.8 1.4 8.4e-15 54.6 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) DJ-1_PfpI PF01965.24 EON32057.1 - 1.4e-23 83.5 0.0 1.7e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Usp PF00582.26 EON32058.1 - 5.3e-20 72.4 0.8 1.3e-19 71.2 0.8 1.6 1 1 0 1 1 1 1 Universal stress protein family Glyco_hydro_3 PF00933.21 EON32059.1 - 8.7e-72 242.2 0.0 9.9e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain hnRNP_Q_AcD PF18360.1 EON32059.1 - 0.011 15.7 0.3 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain TetR_N PF00440.23 EON32060.1 - 1.2e-17 63.4 0.0 2.5e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON32060.1 - 8.3e-05 22.8 0.5 0.00015 22.0 0.5 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EON32060.1 - 0.00031 21.5 0.6 0.00031 21.5 0.6 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 EON32060.1 - 0.01 16.6 0.1 0.019 15.7 0.1 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain P5CR_dimer PF14748.6 EON32060.1 - 0.029 14.6 1.1 7.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation HTH_Tnp_1_2 PF13022.6 EON32060.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase MaoC_dehydratas PF01575.19 EON32061.1 - 6.4e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON32061.1 - 1.3e-06 28.5 0.2 0.016 15.4 0.0 2.5 2 1 1 3 3 3 2 N-terminal half of MaoC dehydratase adh_short_C2 PF13561.6 EON32062.1 - 2.9e-51 174.3 9.7 5.1e-50 170.2 8.8 2.3 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON32062.1 - 2e-46 157.9 5.3 1.4e-45 155.2 4.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EON32062.1 - 1.8e-16 60.5 1.5 4.1e-16 59.4 1.5 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32062.1 - 0.0008 18.9 0.5 0.0021 17.5 0.7 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EON32063.1 - 4.5e-44 150.8 0.1 7.4e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON32063.1 - 2.7e-32 111.0 0.1 4.6e-32 110.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON32063.1 - 0.0016 18.0 0.1 0.0045 16.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EON32063.1 - 0.019 14.8 0.3 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LysR_substrate PF03466.20 EON32063.1 - 0.023 14.0 0.3 0.44 9.9 0.1 2.2 2 0 0 2 2 2 0 LysR substrate binding domain VanW PF04294.13 EON32064.1 - 1.5e-43 147.5 0.0 2.6e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 VanW like protein PG_binding_4 PF12229.8 EON32064.1 - 3.1e-15 56.5 0.0 1.4e-08 35.1 0.0 4.0 3 1 2 5 5 5 2 Putative peptidoglycan binding domain adh_short PF00106.25 EON32065.1 - 4.7e-46 156.7 4.0 5.6e-46 156.5 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32065.1 - 5.5e-46 157.0 5.5 6.7e-46 156.7 5.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32065.1 - 5.4e-06 26.4 8.4 0.00013 21.9 8.4 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32065.1 - 0.00012 21.6 0.3 0.00017 21.1 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON32065.1 - 0.0012 18.8 1.5 0.0016 18.4 1.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 EON32065.1 - 0.0012 18.8 1.7 0.0024 17.8 1.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON32065.1 - 0.0014 18.0 4.1 0.0023 17.3 4.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EON32065.1 - 0.0041 17.2 0.2 0.0087 16.1 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EON32065.1 - 0.0046 17.2 0.7 0.009 16.3 0.7 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 EON32065.1 - 0.011 14.8 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ATPgrasp_N PF18130.1 EON32065.1 - 0.021 15.3 0.2 0.36 11.4 0.1 2.3 2 0 0 2 2 2 0 ATP-grasp N-terminal domain Sacchrp_dh_NADP PF03435.18 EON32065.1 - 0.029 14.6 1.0 0.054 13.8 0.7 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EON32065.1 - 0.1 11.9 0.3 0.22 10.9 0.3 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EON32065.1 - 0.16 11.8 1.0 0.27 11.1 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HdeA PF06411.11 EON32066.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family Na_sulph_symp PF00939.19 EON32067.1 - 1.3e-28 100.3 40.4 1.7e-28 99.9 40.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EON32067.1 - 1.6e-15 57.1 53.0 1.6e-15 57.1 53.0 1.9 1 1 0 1 1 1 1 Citrate transporter Gly_kinase PF02595.15 EON32068.1 - 1.4e-119 399.3 11.9 1.6e-119 399.1 11.9 1.0 1 0 0 1 1 1 1 Glycerate kinase family Acyl-CoA_dh_C PF12806.7 EON32070.1 - 4.4e-32 110.9 0.5 1e-31 109.6 0.5 1.7 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 EON32070.1 - 5.2e-19 68.3 0.1 1.1e-18 67.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON32070.1 - 2.3e-14 53.8 0.5 1.5e-13 51.2 0.5 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 EON32070.1 - 7.4e-09 35.5 0.7 1.4e-08 34.6 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_N PF02771.16 EON32070.1 - 0.00023 21.8 0.0 0.00087 19.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AP_endonuc_2 PF01261.24 EON32072.1 - 4.7e-28 98.1 1.0 7.3e-28 97.4 1.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PAP2_3 PF14378.6 EON32074.1 - 1.7e-21 76.8 21.7 1.7e-21 76.8 21.7 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EON32074.1 - 9.8e-08 31.9 5.0 9.8e-08 31.9 5.0 3.0 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 EON32074.1 - 0.00052 20.5 2.7 0.00052 20.5 2.7 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF305 PF03713.13 EON32076.1 - 6.9e-49 165.9 9.7 8.9e-49 165.5 9.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 EON32076.1 - 4.1e-12 46.5 0.7 3.9e-08 33.6 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4142) DUF3558 PF12079.8 EON32076.1 - 1.9 8.5 7.7 3.3 7.7 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) F420H2_quin_red PF04075.14 EON32077.1 - 1e-27 96.8 0.0 1.1e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Putative_PNPOx PF01243.20 EON32077.1 - 0.00058 20.0 0.0 0.00078 19.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2613 PF11021.8 EON32079.1 - 0.89 9.7 8.8 0.19 11.8 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Arabinose_trans PF04602.12 EON32080.1 - 2e-199 663.2 35.5 2.9e-199 662.6 35.5 1.2 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 EON32080.1 - 5.1e-135 450.4 0.4 7.1e-135 449.9 0.4 1.2 1 0 0 1 1 1 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 EON32080.1 - 1.2e-51 175.0 0.3 1.9e-51 174.3 0.3 1.4 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain DHquinase_II PF01220.19 EON32081.1 - 4.2e-57 191.7 0.0 4.8e-57 191.5 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II AHSA1 PF08327.11 EON32082.1 - 1.4e-05 25.3 0.1 1.9e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EON32082.1 - 0.00091 19.5 0.4 0.0014 18.9 0.4 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HTH_20 PF12840.7 EON32083.1 - 1.4e-14 53.9 0.6 2.2e-14 53.2 0.6 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EON32083.1 - 3.1e-08 33.3 0.0 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EON32083.1 - 3.2e-08 33.3 0.6 5e-08 32.7 0.6 1.2 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 EON32083.1 - 1e-05 25.4 0.1 1.6e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EON32083.1 - 4.6e-05 23.2 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EON32083.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_27 PF13463.6 EON32083.1 - 0.00013 22.4 0.1 0.00021 21.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EON32083.1 - 0.0012 18.3 0.1 0.0021 17.6 0.1 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EON32083.1 - 0.0027 17.6 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 MarR family RP-C PF03428.13 EON32083.1 - 0.0081 15.8 0.2 0.01 15.5 0.2 1.5 1 1 0 1 1 1 1 Replication protein C N-terminal domain Penicillinase_R PF03965.16 EON32083.1 - 0.0099 16.2 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 1 Penicillinase repressor HTH_CodY PF08222.11 EON32083.1 - 0.017 14.7 0.2 0.025 14.1 0.2 1.2 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_Crp_2 PF13545.6 EON32083.1 - 0.029 14.3 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Talin_middle PF09141.10 EON32083.1 - 0.052 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Talin, middle domain HTH_10 PF04967.12 EON32083.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain GntR PF00392.21 EON32083.1 - 0.058 13.0 0.4 0.12 12.0 0.3 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_12 PF08461.10 EON32083.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain DUF2513 PF10711.9 EON32083.1 - 0.078 13.3 0.0 0.09 13.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HxlR PF01638.17 EON32083.1 - 0.096 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF2250 PF10007.9 EON32083.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_36 PF13730.6 EON32083.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AMP-binding PF00501.28 EON32084.1 - 2.7e-62 210.8 0.0 1.9e-50 171.7 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Thioesterase PF00975.20 EON32084.1 - 3.7e-19 69.7 0.1 2.9e-17 63.6 0.1 2.5 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EON32084.1 - 2.3e-13 50.3 0.0 7e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON32084.1 - 8.6e-10 39.5 0.1 3.4e-09 37.5 0.1 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 EON32084.1 - 1.3e-06 29.2 8.5 1.3e-06 29.2 8.5 3.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family Nitroreductase PF00881.24 EON32085.1 - 1.9e-34 119.1 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EON32085.1 - 1e-06 28.5 0.0 4e-05 23.3 0.1 2.6 2 1 1 3 3 3 2 Putative TM nitroreductase CDI PF02234.19 EON32085.1 - 0.031 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Putative_PNPOx PF01243.20 EON32086.1 - 3.5e-07 30.3 0.0 1.6e-06 28.2 0.0 1.9 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Lactamase_B PF00753.27 EON32087.1 - 3.9e-26 92.3 4.3 5.7e-26 91.7 4.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON32087.1 - 2.4e-06 27.2 0.6 3.7e-06 26.6 0.6 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EON32087.1 - 0.034 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain AftA_N PF12250.8 EON32088.1 - 8e-152 505.9 46.8 1e-151 505.6 46.8 1.0 1 0 0 1 1 1 1 Arabinofuranosyltransferase N terminal AftA_C PF12249.8 EON32088.1 - 5.1e-71 238.0 0.1 6.9e-71 237.5 0.1 1.2 1 0 0 1 1 1 1 Arabinofuranosyltransferase A C terminal adh_short PF00106.25 EON32089.1 - 1.3e-25 90.1 0.3 1.5e-25 89.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32089.1 - 7.7e-17 61.6 2.0 9.9e-17 61.3 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32089.1 - 0.0006 19.8 1.2 0.0012 18.8 1.2 1.4 1 1 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 EON32090.1 - 3.3e-24 85.2 0.6 7.3e-24 84.1 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EON32090.1 - 1.5e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase AurF PF11583.8 EON32091.1 - 1.4e-95 319.8 3.2 1.6e-95 319.6 3.2 1.0 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF TetR_C_33 PF13305.6 EON32092.1 - 5.2e-11 43.2 6.4 3.2e-09 37.5 1.4 2.2 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32092.1 - 7.7e-10 38.4 0.6 1.9e-09 37.2 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 EON32092.1 - 0.078 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EON32092.1 - 0.094 12.6 2.2 0.24 11.3 0.1 2.6 3 0 0 3 3 3 0 MarR family HTH_23 PF13384.6 EON32092.1 - 0.14 11.9 0.6 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Peripla_BP_2 PF01497.18 EON32093.1 - 3.1e-26 92.4 0.0 3.9e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 EON32094.1 - 2.1e-88 296.4 36.2 2.6e-88 296.0 36.2 1.0 1 0 0 1 1 1 1 FecCD transport family TNFR_16_TM PF18422.1 EON32094.1 - 0.14 12.1 1.3 0.43 10.6 1.3 1.9 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Tim17 PF02466.19 EON32094.1 - 2.7 8.4 11.9 0.12 12.8 5.9 1.9 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FecCD PF01032.18 EON32095.1 - 1.1e-69 234.8 43.3 1.4e-69 234.5 43.3 1.0 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 EON32096.1 - 5.1e-27 95.1 0.0 7e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32096.1 - 4.9e-13 49.5 0.8 1.7e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON32096.1 - 8.3e-08 31.9 0.0 0.0066 15.9 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EON32096.1 - 6.6e-06 26.1 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EON32096.1 - 0.00013 22.4 0.2 0.00026 21.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON32096.1 - 0.00019 21.1 0.1 0.0004 20.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EON32096.1 - 0.0007 18.5 0.1 0.038 12.8 0.0 2.3 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_27 PF13514.6 EON32096.1 - 0.00076 19.1 0.0 0.0018 17.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EON32096.1 - 0.00077 20.0 0.1 0.0011 19.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON32096.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF2813 PF11398.8 EON32096.1 - 0.015 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Adeno_IVa2 PF02456.15 EON32096.1 - 0.035 12.9 0.1 0.11 11.3 0.1 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_28 PF13521.6 EON32096.1 - 0.036 14.3 0.1 0.15 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EON32096.1 - 0.043 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EON32096.1 - 0.043 14.1 0.2 0.11 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EON32096.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EON32096.1 - 0.053 13.1 1.5 0.22 11.1 0.0 2.3 2 1 1 3 3 3 0 AAA domain ATPase_2 PF01637.18 EON32096.1 - 0.063 13.2 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EON32096.1 - 0.065 13.4 0.1 0.15 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON32096.1 - 0.091 12.5 0.0 6.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EON32096.1 - 0.096 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EON32096.1 - 0.11 12.6 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain FAD_binding_9 PF08021.11 EON32097.1 - 1.4e-35 122.1 0.0 2e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 EON32097.1 - 3.8e-29 101.6 0.1 5.7e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_6 PF00970.24 EON32097.1 - 0.039 14.3 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Erythro-docking PF09277.11 EON32097.1 - 0.055 13.4 0.7 0.19 11.6 0.7 1.9 1 0 0 1 1 1 0 Erythronolide synthase, docking PIN_4 PF13638.6 EON32098.1 - 0.046 14.0 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 PIN domain APC_u13 PF16634.5 EON32098.1 - 0.13 12.1 0.8 0.61 10.0 0.2 2.3 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr and SAMP TetR_C_14 PF17754.1 EON32099.1 - 4.9e-17 61.9 2.4 7.4e-17 61.3 2.4 1.3 1 0 0 1 1 1 1 MftR C-terminal domain TetR_N PF00440.23 EON32099.1 - 2e-14 53.1 0.2 4.5e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON32099.1 - 0.003 17.7 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_31 PF13560.6 EON32099.1 - 0.022 15.1 2.0 0.26 11.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.15 EON32099.1 - 0.039 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON32099.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 EON32099.1 - 0.12 12.4 0.2 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix adh_short_C2 PF13561.6 EON32100.1 - 2.2e-63 214.0 1.2 2.4e-63 213.8 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON32100.1 - 4.1e-53 179.7 1.0 4.8e-53 179.5 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON32100.1 - 9e-06 25.7 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32100.1 - 0.024 14.1 0.2 0.046 13.2 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mycobact_memb PF05423.13 EON32101.1 - 1.5e-13 50.9 0.4 1.8e-13 50.6 0.4 1.1 1 0 0 1 1 1 1 Mycobacterium membrane protein MMPL PF03176.15 EON32102.1 - 2.6e-156 519.7 34.7 2e-90 303.1 13.8 2.5 2 0 0 2 2 2 2 MMPL family NPV_P10 PF05531.12 EON32102.1 - 0.019 15.4 0.0 9.5 6.8 0.0 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5056 PF16479.5 EON32102.1 - 0.34 11.2 1.6 18 5.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) HsbA PF12296.8 EON32102.1 - 9.2 6.7 10.3 1.6 9.2 5.2 2.5 2 1 0 2 2 2 0 Hydrophobic surface binding protein A NAD_binding_8 PF13450.6 EON32103.1 - 1.1e-10 41.6 0.6 4.3e-10 39.7 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON32103.1 - 5.5e-10 39.4 0.1 1.1e-06 28.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON32103.1 - 5.8e-08 32.5 0.0 7.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON32103.1 - 9.5e-08 31.5 0.5 1.7e-07 30.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EON32103.1 - 2.8e-06 26.9 0.8 0.00022 20.7 1.2 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EON32103.1 - 4.1e-05 22.9 0.8 9.3e-05 21.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EON32103.1 - 0.00013 21.2 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EON32103.1 - 0.00036 19.9 0.1 0.0011 18.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON32103.1 - 0.0004 19.7 0.4 0.00075 18.8 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON32103.1 - 0.00053 18.8 0.4 0.00078 18.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EON32103.1 - 0.0098 16.4 2.0 0.014 16.0 0.7 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON32103.1 - 0.016 14.5 0.5 0.023 14.0 0.5 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EON32103.1 - 0.07 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Trp_halogenase PF04820.14 EON32103.1 - 0.11 11.3 0.3 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 EON32103.1 - 0.32 9.7 0.1 0.46 9.2 0.1 1.1 1 0 0 1 1 1 0 MCRA family TrkA_N PF02254.18 EON32103.1 - 0.58 10.4 1.7 0.77 10.0 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.21 EON32104.1 - 1.5e-35 122.8 0.0 1.7e-33 116.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GtrA PF04138.14 EON32105.1 - 4.8e-19 68.7 11.0 5.7e-19 68.5 11.0 1.1 1 0 0 1 1 1 1 GtrA-like protein ABC_tran PF00005.27 EON32106.1 - 1e-54 184.7 0.0 3.7e-28 98.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter BPD_transp_1 PF00528.22 EON32106.1 - 1.6e-29 103.0 15.6 1.6e-29 103.0 15.6 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SMC_N PF02463.19 EON32106.1 - 6.5e-13 48.6 0.3 3.6e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain OppC_N PF12911.7 EON32106.1 - 7.8e-12 45.0 0.4 7.8e-12 45.0 0.4 3.5 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C oligo_HPY PF08352.12 EON32106.1 - 6.6e-08 33.0 0.1 0.0011 19.5 0.1 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 EON32106.1 - 4.1e-05 23.2 4.7 0.0073 16.0 0.8 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EON32106.1 - 0.00044 20.4 1.5 0.54 10.5 0.2 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EON32106.1 - 0.0028 17.7 1.4 2.4 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EON32106.1 - 0.0081 16.0 10.0 0.15 11.8 0.1 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON32106.1 - 0.021 15.1 10.5 4.4 7.6 0.6 4.0 3 1 0 3 3 3 0 AAA domain DUF2275 PF10039.9 EON32106.1 - 0.029 14.5 2.3 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) DUF87 PF01935.17 EON32106.1 - 0.083 13.0 7.1 0.17 12.0 1.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 EON32106.1 - 0.093 13.2 1.6 0.49 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EON32106.1 - 0.1 12.1 9.7 0.39 10.3 2.5 3.6 2 2 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EON32106.1 - 0.17 11.6 0.2 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 EON32106.1 - 1.2 9.0 4.2 2.6 7.9 0.5 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EON32106.1 - 1.7 8.4 13.2 2.7 7.6 5.3 3.5 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EON32106.1 - 1.9 8.2 2.9 20 4.8 0.7 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EON32106.1 - 1.9 8.8 12.9 3.6 7.9 4.3 2.9 2 2 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EON32106.1 - 1.9 8.3 4.8 2.1 8.2 0.4 2.6 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.26 EON32106.1 - 4.1 7.1 4.6 7.9 6.1 0.2 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain BPD_transp_1 PF00528.22 EON32107.1 - 1.3e-43 148.9 11.4 1.3e-43 148.9 11.4 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 EON32108.1 - 4.9e-95 318.7 0.3 6.5e-95 318.3 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Bac_luciferase PF00296.20 EON32109.1 - 9.3e-47 160.0 0.1 1.1e-46 159.7 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase HxlR PF01638.17 EON32110.1 - 2.9e-23 81.5 0.0 4e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EON32110.1 - 0.033 14.1 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 EON32110.1 - 0.051 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain 4HBT_3 PF13622.6 EON32111.1 - 2.9e-27 96.5 4.8 3.3e-27 96.3 4.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EON32111.1 - 0.052 13.9 0.8 0.23 11.9 0.8 2.0 1 1 0 1 1 1 0 Thioesterase superfamily MFS_1 PF07690.16 EON32112.1 - 2.2e-40 138.7 50.4 2.2e-40 138.7 50.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32112.1 - 3.2e-05 23.0 9.1 3.2e-05 23.0 9.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter COX7C PF02935.16 EON32112.1 - 6.9 7.0 6.3 4.9 7.5 0.9 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Glycos_transf_2 PF00535.26 EON32113.1 - 4.7e-09 36.3 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32113.1 - 1.6e-08 34.7 0.3 1.3e-07 31.7 0.3 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EON32113.1 - 0.021 15.3 0.0 0.28 11.7 0.0 2.3 1 1 1 2 2 2 0 Glycosyl transferase family 2 ABC_tran PF00005.27 EON32114.1 - 7.3e-20 71.9 0.0 2.8e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32114.1 - 6.8e-05 22.8 0.6 0.003 17.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EON32114.1 - 0.0049 16.8 0.2 0.015 15.2 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EON32114.1 - 0.011 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON32114.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EON32114.1 - 0.019 15.4 0.1 0.028 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EON32114.1 - 0.021 15.3 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EON32114.1 - 0.074 10.6 0.2 0.1 10.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_15 PF13175.6 EON32114.1 - 0.094 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane PF01061.24 EON32115.1 - 3.9e-25 88.5 17.2 6e-25 87.9 17.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter DUF2587 PF10759.9 EON32116.1 - 2.6e-79 264.3 1.0 2.8e-79 264.2 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) FliT PF05400.13 EON32116.1 - 0.37 11.6 4.9 0.16 12.8 2.0 1.8 2 0 0 2 2 2 0 Flagellar protein FliT Aminotran_5 PF00266.19 EON32117.1 - 1.6e-31 109.6 0.0 9e-26 90.7 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EON32117.1 - 8.4e-09 34.4 0.0 1.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.16 EON32117.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.17 EON32117.1 - 0.047 13.0 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MarR_2 PF12802.7 EON32118.1 - 6.9e-09 35.5 0.6 1.5e-08 34.4 0.2 1.8 2 0 0 2 2 2 1 MarR family MarR PF01047.22 EON32118.1 - 8.6e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EON32118.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EON32118.1 - 3.3e-05 23.3 0.0 5.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EON32118.1 - 3.5e-05 24.2 0.1 4.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_1 PF00126.27 EON32118.1 - 4.6e-05 23.3 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 EON32118.1 - 0.00026 20.7 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 EON32118.1 - 0.00034 20.5 0.3 0.00092 19.1 0.2 1.8 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EON32118.1 - 0.00041 20.5 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 EON32118.1 - 0.0014 18.8 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Penicillinase_R PF03965.16 EON32118.1 - 0.013 15.9 0.0 0.018 15.4 0.0 1.3 1 1 0 1 1 1 0 Penicillinase repressor SurA_N_2 PF13623.6 EON32118.1 - 0.022 14.6 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain PadR PF03551.14 EON32118.1 - 0.043 13.8 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Crp PF00325.20 EON32118.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Sigma54_DBD PF04552.13 EON32118.1 - 0.067 12.9 0.3 0.13 12.0 0.1 1.5 2 0 0 2 2 2 0 Sigma-54, DNA binding domain HTH_AsnC-type PF13404.6 EON32118.1 - 0.069 13.0 2.3 0.15 11.9 0.2 2.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain RPA_C PF08784.11 EON32118.1 - 0.14 12.8 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal ADH_zinc_N PF00107.26 EON32119.1 - 3.3e-28 98.2 0.3 5.9e-28 97.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON32119.1 - 3.6e-23 83.1 0.1 8.5e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON32119.1 - 1e-09 38.2 0.2 3.7e-08 33.2 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EON32119.1 - 0.00023 20.7 0.1 0.0005 19.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EON32119.1 - 0.001 18.4 0.6 0.0077 15.6 0.2 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 EON32119.1 - 0.011 15.8 0.0 3.3 7.8 0.0 2.4 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Glu_dehyd_C PF16912.5 EON32119.1 - 0.034 13.6 0.3 0.05 13.1 0.3 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus adh_short_C2 PF13561.6 EON32119.1 - 0.038 13.5 0.5 0.082 12.4 0.5 1.6 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase YAcAr PF10686.9 EON32119.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family NAD_binding_10 PF13460.6 EON32119.1 - 0.08 12.8 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding HATPase_c_4 PF13749.6 EON32120.1 - 9.4e-19 67.4 0.0 2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Putative ATP-dependent DNA helicase recG C-terminal AlbA_2 PF04326.14 EON32120.1 - 2.8e-12 47.0 0.0 4.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain Exo_endo_phos PF03372.23 EON32121.1 - 2.9e-19 69.5 2.6 4e-19 69.0 2.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_11 PF08241.12 EON32122.1 - 8.1e-20 71.3 0.0 1.5e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32122.1 - 5.7e-18 65.4 0.1 1.1e-17 64.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON32122.1 - 1e-14 54.5 0.0 1.5e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EON32122.1 - 4.8e-08 32.9 0.0 6.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32122.1 - 1.7e-05 25.5 0.0 2.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EON32122.1 - 0.0011 18.7 0.1 0.002 17.9 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_8 PF05148.15 EON32122.1 - 0.0037 17.1 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 EON32122.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EON32122.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 EON32122.1 - 0.031 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HTH_18 PF12833.7 EON32122.1 - 0.07 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MTS PF05175.14 EON32122.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EON32122.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HxlR PF01638.17 EON32123.1 - 9.9e-22 76.6 0.3 1.6e-21 76.0 0.3 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix SCP2 PF02036.17 EON32123.1 - 4e-05 24.0 0.0 9.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family PadR PF03551.14 EON32123.1 - 0.028 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MarR PF01047.22 EON32123.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF505 PF04458.12 EON32123.1 - 0.053 11.9 0.0 0.07 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) DUF4423 PF14394.6 EON32123.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) ABC2_membrane_2 PF12679.7 EON32124.1 - 1.5e-13 50.7 25.5 2.5e-13 49.9 25.5 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EON32124.1 - 0.5 9.7 25.0 0.16 11.4 9.6 3.0 2 1 1 3 3 3 0 ABC-2 type transporter ABC_tran PF00005.27 EON32125.1 - 2.6e-25 89.5 0.0 3.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32125.1 - 3.2e-14 53.4 0.0 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON32125.1 - 0.0051 17.3 0.1 0.0071 16.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON32125.1 - 0.02 15.2 0.0 0.09 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EON32125.1 - 0.029 13.3 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EON32125.1 - 0.045 13.5 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON32125.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EON32125.1 - 0.11 12.2 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 EON32125.1 - 0.23 11.0 0.2 0.59 9.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain CorA PF01544.18 EON32126.1 - 1.3e-61 208.5 0.1 5e-60 203.3 0.1 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 4HBT_2 PF13279.6 EON32128.1 - 5.9e-09 36.5 0.0 7.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EON32128.1 - 3.4e-06 27.3 0.1 6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EON32128.1 - 0.0043 16.4 0.0 0.0058 15.9 0.0 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase Esterase PF00756.20 EON32129.1 - 2.5e-36 125.6 0.0 4.2e-36 124.9 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 EON32129.1 - 0.016 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.16 EON32129.1 - 0.066 13.0 0.0 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EON32129.1 - 0.066 12.7 0.1 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 EON32129.1 - 0.068 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON32129.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EON32129.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Aminotran_1_2 PF00155.21 EON32130.1 - 8.8e-51 173.2 0.0 1e-50 173.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EON32130.1 - 0.00032 19.8 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EON32130.1 - 0.0019 17.6 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EON32130.1 - 0.021 13.4 0.1 0.037 12.6 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme HNOB PF07700.15 EON32130.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Haem-NO-binding Alliinase_C PF04864.13 EON32130.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.6 1 1 0 1 1 1 0 Allinase AAA_19 PF13245.6 EON32131.1 - 7.9e-11 42.5 0.1 0.00015 22.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EON32131.1 - 1.1e-07 31.8 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EON32131.1 - 2.4e-06 27.3 0.1 3.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EON32131.1 - 8.2e-06 25.7 0.0 0.17 11.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EON32131.1 - 1.4e-05 24.7 0.1 0.0065 15.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 EON32131.1 - 0.00073 18.9 0.1 0.0075 15.5 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EON32131.1 - 0.001 18.8 1.7 0.99 9.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain UvrD_C PF13361.6 EON32131.1 - 0.0011 18.5 0.0 0.062 12.7 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EON32131.1 - 0.0012 19.1 0.1 2.9 8.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EON32131.1 - 0.11 12.8 1.9 2.6 8.4 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Mycobact_memb PF05423.13 EON32132.1 - 0.0017 18.3 0.0 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 Mycobacterium membrane protein Glycolipid_bind PF06475.11 EON32133.1 - 4.2e-47 159.9 0.0 4.7e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Putative glycolipid-binding DUF4302 PF14135.6 EON32133.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) PDH PF02153.17 EON32134.1 - 1.1e-44 152.4 0.1 1.3e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EON32134.1 - 1.7e-05 25.0 0.1 5.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EON32134.1 - 0.00026 21.5 0.1 0.00066 20.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MafB19-deam PF14437.6 EON32136.1 - 1.8e-22 79.6 0.0 1.9e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EON32136.1 - 2e-22 79.0 0.0 2.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 EON32136.1 - 0.014 15.5 3.2 0.28 11.2 3.2 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase DUF1542 PF07564.11 EON32137.1 - 0.0026 17.8 8.7 0.29 11.3 2.7 2.1 1 1 1 2 2 2 2 Domain of Unknown Function (DUF1542) DUF4455 PF14643.6 EON32137.1 - 0.0095 14.6 2.6 0.011 14.4 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) YtxH PF12732.7 EON32137.1 - 0.024 15.1 9.8 9.1 6.9 9.8 2.3 1 1 0 1 1 1 0 YtxH-like protein GRA6 PF05084.13 EON32137.1 - 0.065 13.2 1.2 0.075 13.0 1.2 1.0 1 0 0 1 1 1 0 Granule antigen protein (GRA6) AF0941-like PF14591.6 EON32137.1 - 0.078 13.5 2.4 0.099 13.2 1.9 1.4 1 1 0 1 1 1 0 AF0941-like EntA_Immun PF08951.10 EON32137.1 - 0.079 13.3 2.3 1.6 9.2 0.8 2.5 1 1 2 3 3 3 0 Enterocin A Immunity Tape_meas_lam_C PF09718.10 EON32137.1 - 0.091 12.9 0.6 12 6.2 0.1 2.2 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PRP1_N PF06424.12 EON32137.1 - 0.098 13.0 3.5 0.12 12.8 3.5 1.2 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Apo-CIII PF05778.12 EON32137.1 - 0.13 11.9 1.6 1.7 8.3 0.5 2.3 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) CsbD PF05532.12 EON32137.1 - 0.45 10.4 7.8 2.4 8.1 0.2 3.4 3 1 0 3 3 3 0 CsbD-like Toxin_38 PF14866.6 EON32137.1 - 0.66 10.3 2.0 39 4.6 0.5 3.2 2 1 1 3 3 3 0 Potassium channel toxin XhlA PF10779.9 EON32137.1 - 0.77 10.0 3.7 1.3 9.2 0.9 2.1 2 1 0 2 2 2 0 Haemolysin XhlA MT0933_antitox PF14013.6 EON32137.1 - 1.4 9.3 10.5 4.2 7.8 1.7 2.9 1 1 1 2 2 2 0 MT0933-like antitoxin protein CsbD PF05532.12 EON32138.1 - 2.2e-12 46.7 15.9 2.2e-12 46.7 15.9 1.7 1 1 1 2 2 2 1 CsbD-like YtxH PF12732.7 EON32138.1 - 0.035 14.7 8.4 0.063 13.8 8.4 1.4 1 1 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.16 EON32138.1 - 0.099 12.7 12.2 0.24 11.5 1.0 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein Fic_N PF13784.6 EON32139.1 - 8e-20 70.7 1.6 1.8e-19 69.5 1.6 1.6 1 0 0 1 1 1 1 Fic/DOC family N-terminal Fic PF02661.18 EON32139.1 - 1.2e-17 64.5 0.0 2.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family DUF1612 PF07756.12 EON32139.1 - 0.0012 19.1 0.2 0.0029 17.8 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1612) MspA PF09203.11 EON32140.1 - 2.4e-36 125.2 9.4 3.5e-36 124.7 9.4 1.2 1 0 0 1 1 1 1 MspA MspA PF09203.11 EON32141.1 - 3.7e-23 82.3 10.1 4.6e-20 72.2 5.0 2.6 1 1 0 2 2 2 2 MspA AMP-binding PF00501.28 EON32142.1 - 2.2e-07 29.8 0.6 3.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Sigma70_r4 PF04545.16 EON32143.1 - 3e-08 33.0 2.2 6.1e-07 28.9 2.0 2.8 2 0 0 2 2 2 1 Sigma-70, region 4 HARE-HTH PF05066.13 EON32143.1 - 0.16 12.3 0.0 51 4.4 0.0 3.6 4 0 0 4 4 4 0 HB1, ASXL, restriction endonuclease HTH domain DUF4777 PF16007.5 EON32143.1 - 0.17 12.2 0.1 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) HTH_Tnp_ISL3 PF13542.6 EON32143.1 - 0.66 9.4 0.0 0.66 9.4 0.0 4.0 5 0 0 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 AMP-binding PF00501.28 EON32144.1 - 2.9e-106 355.6 0.0 3.5e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON32144.1 - 9e-22 77.9 0.5 2.6e-21 76.4 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TetR_C_11 PF16859.5 EON32144.1 - 0.091 13.1 1.8 0.28 11.5 1.8 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3556 PF12077.8 EON32145.1 - 6.4e-273 906.4 7.3 7.2e-273 906.3 7.3 1.0 1 0 0 1 1 1 1 Transmembrane protein of unknown function (DUF3556) NAD_binding_8 PF13450.6 EON32146.1 - 4.3e-11 42.9 0.9 4.3e-11 42.9 0.9 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON32146.1 - 4.3e-07 29.8 10.2 6.1e-06 26.0 5.6 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON32146.1 - 1.6e-06 27.7 0.4 3.4e-06 26.6 0.2 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EON32146.1 - 2.8e-06 26.8 0.6 4.7e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EON32146.1 - 3.5e-06 26.6 2.3 6.6e-06 25.7 2.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON32146.1 - 4.9e-05 22.7 2.2 6.8e-05 22.3 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON32146.1 - 0.00013 21.3 1.0 0.00022 20.5 1.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON32146.1 - 0.00051 18.9 1.5 0.00074 18.3 1.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EON32146.1 - 0.0006 19.0 3.0 0.00095 18.3 3.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EON32146.1 - 0.0012 18.2 0.6 0.0018 17.6 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32146.1 - 0.0041 17.6 1.0 0.012 16.1 1.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON32146.1 - 0.0054 15.6 0.8 0.0076 15.1 0.8 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EON32146.1 - 0.0063 16.5 0.6 0.021 14.8 0.6 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.22 EON32146.1 - 0.014 14.5 2.5 0.021 13.9 2.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EON32146.1 - 0.088 11.8 1.4 0.14 11.2 1.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 EON32146.1 - 0.3 9.8 0.1 0.39 9.5 0.1 1.1 1 0 0 1 1 1 0 MCRA family GGDEF_2 PF17853.1 EON32147.1 - 6.5e-12 45.7 3.1 9.1e-12 45.3 1.4 2.1 2 0 0 2 2 2 1 GGDEF-like domain HTH_30 PF13556.6 EON32147.1 - 7.5e-10 38.5 2.1 7.5e-10 38.5 2.1 2.5 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain Sigma70_r4_2 PF08281.12 EON32147.1 - 0.06 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 NapD PF03927.13 EON32147.1 - 0.11 12.6 0.8 0.24 11.5 0.8 1.5 1 0 0 1 1 1 0 NapD protein Sulfate_transp PF00916.20 EON32148.1 - 2.4e-74 250.4 29.0 3.4e-74 249.9 29.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EON32148.1 - 4e-16 58.7 0.0 9.1e-15 54.3 0.0 2.2 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 EON32148.1 - 0.17 12.2 1.6 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 STAS domain NrfD_2 PF14589.6 EON32149.1 - 0.039 13.9 0.5 0.06 13.3 0.5 1.2 1 0 0 1 1 1 0 Polysulfide reductase TetR_N PF00440.23 EON32150.1 - 9.3e-18 63.8 0.7 2.1e-17 62.6 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON32150.1 - 0.059 13.6 0.5 0.059 13.6 0.5 2.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EamA PF00892.20 EON32151.1 - 1.8e-21 76.8 36.6 7.9e-11 42.3 16.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EON32151.1 - 0.11 11.7 0.2 0.11 11.7 0.2 1.8 2 0 0 2 2 2 0 Nucleotide-sugar transporter EcsC PF12787.7 EON32151.1 - 0.17 11.5 0.5 0.3 10.7 0.5 1.3 1 0 0 1 1 1 0 EcsC protein family SKG6 PF08693.10 EON32151.1 - 2.9 7.4 9.6 0.63 9.5 1.9 3.5 3 0 0 3 3 3 0 Transmembrane alpha-helix domain DUF3556 PF12077.8 EON32152.1 - 3.7e-269 894.0 3.7 4.2e-269 893.8 3.7 1.0 1 0 0 1 1 1 1 Transmembrane protein of unknown function (DUF3556) FR47 PF08445.10 EON32154.1 - 2.1e-21 75.7 0.0 3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EON32154.1 - 1.2e-11 44.8 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON32154.1 - 1.4e-07 31.8 0.0 2.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON32154.1 - 2e-07 31.0 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EON32154.1 - 0.00083 19.0 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 EON32154.1 - 0.0049 17.0 0.0 0.025 14.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EON32154.1 - 0.022 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON32154.1 - 0.099 13.3 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON32154.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LppA PF16708.5 EON32155.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium WXG100 PF06013.12 EON32156.1 - 1.2e-12 47.8 1.5 1.4e-12 47.6 1.5 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 EON32156.1 - 3.5e-07 30.6 2.5 3.9e-07 30.5 2.5 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm PE PF00934.20 EON32156.1 - 0.1 12.9 3.2 0.8 10.1 3.2 2.0 1 1 0 1 1 1 0 PE family LppA PF16708.5 EON32157.1 - 1.5e-35 122.4 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein confined to pathogenic Mycobacterium MerR-DNA-bind PF09278.11 EON32157.1 - 0.056 14.0 0.2 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 MerR, DNA binding Abhydrolase_8 PF06259.12 EON32158.1 - 5.6e-48 162.9 0.2 1.3e-46 158.5 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 EON32158.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold YkyA PF10368.9 EON32158.1 - 0.16 11.6 1.0 0.31 10.7 1.0 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DivIC PF04977.15 EON32158.1 - 4.1 7.2 4.8 1.2 9.0 0.8 2.1 2 1 1 3 3 3 0 Septum formation initiator NT5C PF06941.12 EON32159.1 - 2.7e-09 37.2 0.0 3.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) OsmC PF02566.19 EON32160.1 - 1.8e-20 73.3 0.0 2.8e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein DUF572 PF04502.13 EON32161.1 - 0.19 11.3 1.5 0.21 11.2 1.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PhoD PF09423.10 EON32162.1 - 1.5e-70 238.0 0.0 1.7e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EON32162.1 - 4.8e-16 59.1 0.1 1e-15 58.0 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain TAT_signal PF10518.9 EON32162.1 - 7.1 6.7 7.3 28 4.8 7.3 2.0 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Transpeptidase PF00905.22 EON32163.1 - 1.5e-37 129.5 0.0 2.1e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain MecA_N PF05223.11 EON32163.1 - 5.2e-05 23.5 0.0 8.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain Beta-lactamase2 PF13354.6 EON32164.1 - 3.2e-43 147.7 0.0 6.8e-43 146.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EON32164.1 - 0.00023 20.5 1.6 0.002 17.4 1.6 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S13 PF02113.15 EON32164.1 - 0.0047 15.7 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.20 EON32164.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HTH_1 PF00126.27 EON32165.1 - 6.2e-22 77.3 1.4 1.4e-21 76.2 1.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EON32165.1 - 2e-15 56.8 4.5 3.7e-15 55.9 4.5 1.4 1 0 0 1 1 1 1 LysR substrate binding domain Abhydrolase_1 PF00561.20 EON32166.1 - 5.1e-25 88.6 0.1 7.3e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON32166.1 - 6.6e-16 59.6 12.5 8.5e-16 59.2 12.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON32166.1 - 1.4e-09 37.6 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EON32166.1 - 0.0073 15.9 0.0 0.8 9.2 0.0 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family AbiEi_1 PF09407.10 EON32166.1 - 0.046 14.0 0.2 0.089 13.1 0.1 1.6 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain DUF5010 PF16402.5 EON32166.1 - 0.08 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Band_7 PF01145.25 EON32167.1 - 2.9e-12 46.9 1.2 3.8e-12 46.6 1.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family 3HCDH_N PF02737.18 EON32168.1 - 3.8e-61 206.1 1.4 8.3e-61 205.0 1.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EON32168.1 - 1.1e-33 116.6 0.5 1.9e-33 115.8 0.5 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EON32168.1 - 2.2e-20 73.1 0.1 1.2e-19 70.7 0.0 2.4 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 EON32168.1 - 2.5e-19 70.0 0.2 4.7e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UDPG_MGDP_dh_N PF03721.14 EON32168.1 - 0.0023 17.6 0.1 0.0045 16.6 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 EON32168.1 - 0.0057 16.9 0.2 0.013 15.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 EON32168.1 - 0.0068 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EON32168.1 - 0.0084 16.7 0.2 0.023 15.3 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EON32168.1 - 0.015 14.7 0.2 0.032 13.6 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EON32168.1 - 0.026 14.1 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 EON32168.1 - 0.039 13.9 0.2 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 EON32168.1 - 0.048 12.7 0.9 0.093 11.8 0.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EON32168.1 - 0.081 13.4 0.7 0.22 12.0 0.7 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EON32168.1 - 0.14 12.3 0.5 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EON32168.1 - 0.3 10.6 3.8 0.26 10.8 1.2 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EON32169.1 - 1.4e-52 178.7 0.0 7.6e-50 169.7 0.0 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON32169.1 - 6.1e-48 161.5 0.1 1.8e-47 160.0 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 EON32169.1 - 3.6e-05 23.8 0.1 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 EON32169.1 - 0.0012 18.5 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain TetR_N PF00440.23 EON32170.1 - 3.9e-35 119.4 2.2 9.3e-17 60.6 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON32170.1 - 0.00036 20.7 0.0 0.75 10.0 0.0 2.6 3 0 0 3 3 3 2 Helix-turn-helix of insertion element transposase TetR_C_24 PF17932.1 EON32170.1 - 0.0012 19.1 0.3 0.027 14.7 0.0 3.0 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain GP57 PF17594.2 EON32170.1 - 0.0026 17.5 0.1 3 7.6 0.0 2.7 2 0 0 2 2 2 2 Phage Tail fiber assembly helper gene product 57 HTH_IclR PF09339.10 EON32170.1 - 0.017 14.9 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_29 PF13551.6 EON32170.1 - 0.036 14.1 0.1 5.3 7.1 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn helix TrbI_Ftype PF09677.10 EON32170.1 - 0.051 13.9 0.1 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) TetR_C_15 PF17918.1 EON32170.1 - 0.052 14.3 12.7 0.067 13.9 0.2 4.2 3 1 2 5 5 5 0 Tetracyclin repressor-like, C-terminal domain HTH_AsnC-type PF13404.6 EON32170.1 - 0.064 13.1 0.5 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 EON32170.1 - 0.38 10.9 3.3 44 4.3 0.1 3.8 4 0 0 4 4 4 0 Helix-turn-helix domain TetR_C_24 PF17932.1 EON32171.1 - 1.2e-15 57.7 0.2 2.5e-15 56.7 0.2 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32171.1 - 7.4e-10 38.5 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 EON32171.1 - 0.0025 17.8 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TP_methylase PF00590.20 EON32171.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF825 PF05695.12 EON32171.1 - 0.29 8.2 0.0 0.36 7.9 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Guanylate_cyc PF00211.20 EON32172.1 - 5.5e-12 45.7 0.0 3.3e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ABC_tran PF00005.27 EON32173.1 - 4.1e-30 105.1 0.0 6.5e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 EON32173.1 - 5.1e-11 42.7 2.2 5.1e-11 42.7 2.2 3.3 3 0 0 3 3 3 1 TOBE domain AAA_21 PF13304.6 EON32173.1 - 6.6e-11 42.6 0.1 0.00031 20.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON32173.1 - 2e-05 24.2 0.1 8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON32173.1 - 4.1e-05 23.1 0.1 0.011 15.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON32173.1 - 4.4e-05 23.9 0.4 7.8e-05 23.1 0.4 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EON32173.1 - 0.0017 18.9 0.0 0.0026 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 EON32173.1 - 0.0046 16.6 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain TOBE_2 PF08402.10 EON32173.1 - 0.0069 16.5 3.6 0.051 13.7 0.7 2.7 1 1 1 2 2 2 1 TOBE domain SbcCD_C PF13558.6 EON32173.1 - 0.0069 16.6 0.3 0.067 13.4 0.3 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EON32173.1 - 0.019 14.7 0.6 0.042 13.6 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EON32173.1 - 0.021 14.8 0.1 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EON32173.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EON32173.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EON32173.1 - 0.043 14.1 0.3 0.17 12.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain HrpE PF06188.12 EON32173.1 - 0.11 12.4 0.5 0.17 11.7 0.5 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E NACHT PF05729.12 EON32173.1 - 0.14 12.1 0.0 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 EON32173.1 - 0.18 10.6 1.7 9.1 4.9 0.5 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 EON32173.1 - 0.28 10.7 3.7 0.48 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 EON32173.1 - 0.36 8.3 0.0 0.45 8.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BPD_transp_1 PF00528.22 EON32174.1 - 3.7e-20 72.5 15.5 3.7e-20 72.5 15.5 1.5 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_11 PF13531.6 EON32175.1 - 3e-38 131.9 2.7 3.5e-38 131.6 2.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EON32175.1 - 6.3e-13 49.4 1.4 2.3e-10 40.9 1.4 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 EON32175.1 - 3.5e-06 26.3 0.8 1e-05 24.7 0.8 1.9 1 1 0 1 1 1 1 PBP superfamily domain OpuAC PF04069.12 EON32175.1 - 2.3e-05 24.1 0.3 4.2e-05 23.3 0.3 1.3 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system LysR_substrate PF03466.20 EON32175.1 - 0.00059 19.3 0.0 0.0017 17.8 0.0 1.7 1 1 1 2 2 2 1 LysR substrate binding domain PBP_like_2 PF12849.7 EON32175.1 - 0.0022 17.7 7.5 0.0051 16.5 7.5 1.5 1 1 0 1 1 1 1 PBP superfamily domain TOBE PF03459.17 EON32176.1 - 1.6e-10 41.1 0.7 1.6e-10 41.1 0.7 1.7 2 0 0 2 2 2 1 TOBE domain HTH_17 PF12728.7 EON32176.1 - 0.0044 17.2 0.0 0.0062 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 EON32176.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein ABC_tran PF00005.27 EON32177.1 - 8.2e-28 97.6 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32177.1 - 6.6e-14 52.4 0.1 1.6e-10 41.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EON32177.1 - 0.0027 18.4 0.0 0.0055 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) Mg_chelatase PF01078.21 EON32177.1 - 0.01 15.2 0.9 1.1 8.5 0.2 2.8 1 1 2 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 EON32177.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EON32177.1 - 0.019 15.4 0.1 0.22 12.0 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EON32177.1 - 0.019 15.3 1.0 0.062 13.7 0.9 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EON32177.1 - 0.023 15.0 0.4 0.21 11.8 0.4 2.1 1 1 0 1 1 1 0 AAA domain Lum_binding PF00677.17 EON32177.1 - 0.028 14.4 0.1 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 Lumazine binding domain AAA_30 PF13604.6 EON32177.1 - 0.031 14.0 1.6 2.2 8.0 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EON32177.1 - 0.051 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EON32177.1 - 0.12 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EON32177.1 - 0.16 11.4 0.0 12 5.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 EON32178.1 - 2.1e-35 122.1 20.5 2.1e-35 122.1 20.5 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON32178.1 - 2.5e-16 59.7 21.3 3.8e-16 59.1 21.3 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON32178.1 - 1.1e-06 28.1 12.8 1.6e-06 27.6 12.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 EON32178.1 - 0.00045 19.8 11.3 0.00077 19.1 11.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein 7TMR-DISM_7TM PF07695.11 EON32178.1 - 2.3 8.1 17.7 0.74 9.7 14.5 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling ROK PF00480.20 EON32179.1 - 7.9e-22 78.1 0.0 1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 EON32179.1 - 3.1e-07 29.8 0.6 7.1e-06 25.5 0.0 3.0 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON32179.1 - 1.5e-05 24.8 0.6 1.5e-05 24.8 0.6 3.3 4 1 0 4 4 4 1 MarR family HTH_Crp_2 PF13545.6 EON32179.1 - 0.00028 20.8 0.1 0.00075 19.4 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EON32179.1 - 0.0059 16.4 1.6 0.11 12.3 0.1 3.3 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EON32179.1 - 0.0068 16.4 0.9 0.037 14.1 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 EON32179.1 - 0.0081 16.0 0.2 0.31 11.0 0.0 2.8 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EON32179.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 EON32179.1 - 0.037 13.9 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Crp PF00325.20 EON32179.1 - 0.041 13.6 0.1 0.21 11.3 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, crp family HTH_Tnp_ISL3 PF13542.6 EON32179.1 - 0.085 12.3 0.8 2.5 7.6 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EON32179.1 - 0.089 12.5 0.3 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_29 PF13551.6 EON32179.1 - 0.091 12.8 3.6 4.2 7.5 0.1 3.1 4 0 0 4 4 3 0 Winged helix-turn helix HTH_AsnC-type PF13404.6 EON32179.1 - 0.11 12.3 1.3 15 5.5 0.0 3.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 EON32179.1 - 0.12 12.6 0.1 9.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 EON32179.1 - 7.8 6.9 10.8 1.2 9.6 0.2 3.9 3 2 1 4 4 4 0 Helix-turn-helix domain Sigma70_r2 PF04542.14 EON32180.1 - 7.5e-20 70.5 0.3 2.3e-19 68.9 0.3 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON32180.1 - 3.1e-14 52.4 0.2 3.1e-14 52.4 0.2 2.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON32180.1 - 8.7e-09 34.8 0.3 1.6e-08 33.9 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 SnoaL_4 PF13577.6 EON32180.1 - 9.8e-08 32.2 0.1 5e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 SnoaL-like domain SnoaL_2 PF12680.7 EON32180.1 - 4.1e-06 27.4 1.0 2.7e-05 24.7 0.0 2.5 3 0 0 3 3 3 1 SnoaL-like domain NTF2 PF02136.20 EON32180.1 - 0.0032 18.0 0.0 0.0081 16.7 0.0 1.7 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain HTH_23 PF13384.6 EON32180.1 - 0.0032 17.2 0.4 0.0032 17.2 0.4 2.1 2 0 0 2 2 2 1 Homeodomain-like domain SnoaL_3 PF13474.6 EON32180.1 - 0.02 15.1 0.0 0.076 13.3 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain HTH_10 PF04967.12 EON32180.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 HTH DNA binding domain His_Phos_1 PF00300.22 EON32182.1 - 8.9e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.25 EON32183.1 - 1.1e-45 155.5 0.1 1.4e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32183.1 - 1.6e-33 116.2 2.2 2.1e-33 115.9 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32183.1 - 1.7e-10 41.1 0.4 2.5e-10 40.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32183.1 - 1.1e-06 28.4 0.1 2.6e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON32183.1 - 0.00052 20.0 2.1 0.00078 19.4 2.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Peripla_BP_5 PF13433.6 EON32183.1 - 0.008 15.2 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF1776 PF08643.10 EON32183.1 - 0.078 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EON32183.1 - 0.089 12.3 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 EON32183.1 - 0.12 12.6 0.6 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 EON32183.1 - 0.16 11.3 0.0 0.85 9.0 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase APH PF01636.23 EON32184.1 - 6.9e-42 144.0 2.6 8.7e-42 143.7 2.6 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EON32184.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 Ecdysteroid kinase Barstar PF01337.18 EON32184.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Fructosamin_kin PF03881.14 EON32184.1 - 0.085 12.0 0.0 0.19 10.9 0.0 1.6 1 1 0 1 1 1 0 Fructosamine kinase Acyl-CoA_dh_1 PF00441.24 EON32185.1 - 7e-35 120.4 0.4 9.9e-35 120.0 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON32185.1 - 1.1e-18 67.2 0.0 1.7e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON32185.1 - 1.3e-14 54.8 0.1 4.2e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON32185.1 - 2.6e-11 43.9 0.0 2.6e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON32185.1 - 8.9e-05 22.3 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AAA_assoc_2 PF16193.5 EON32185.1 - 0.021 15.2 0.6 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA C-terminal domain TetR_C_24 PF17932.1 EON32186.1 - 7.2e-24 84.2 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32186.1 - 2e-17 62.7 0.1 4.3e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 EON32186.1 - 3.4e-06 27.1 0.2 8.9e-06 25.7 0.1 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EON32186.1 - 0.029 14.6 1.4 0.12 12.6 0.1 2.3 2 2 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal TetR_C_4 PF08359.11 EON32186.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region TetR_N PF00440.23 EON32187.1 - 1.1e-05 25.1 0.2 2.6e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DUF2236 PF09995.9 EON32188.1 - 1.7e-38 133.1 0.6 2.4e-38 132.6 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DEDD_Tnp_IS110 PF01548.17 EON32189.1 - 3.2e-21 75.8 0.0 9e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 EON32189.1 - 3.6e-20 72.1 0.1 7.1e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HHH_5 PF14520.6 EON32189.1 - 0.029 14.9 0.2 6.2 7.5 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 EON32189.1 - 0.16 11.9 0.1 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif FMN_dh PF01070.18 EON32190.1 - 1.4e-120 402.5 1.3 1.7e-120 402.3 1.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EON32190.1 - 0.0001 21.6 0.2 0.00015 21.0 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EON32190.1 - 0.0012 18.2 0.7 0.74 9.1 0.1 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EON32190.1 - 0.01 14.8 2.6 0.021 13.8 2.6 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 EON32190.1 - 0.066 12.5 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 Thiamine monophosphate synthase polyprenyl_synt PF00348.17 EON32192.1 - 4.6e-48 163.5 0.1 6.8e-48 163.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase NEL PF14496.6 EON32192.1 - 0.021 14.2 0.5 0.078 12.4 0.1 1.9 2 0 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting DUF3291 PF11695.8 EON32193.1 - 0.00055 19.6 0.0 0.0081 15.8 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3291) ABM PF03992.16 EON32193.1 - 0.012 15.7 0.5 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Caroten_synth PF04240.12 EON32194.1 - 2.9e-41 141.6 17.1 5e-41 140.9 17.1 1.3 1 0 0 1 1 1 1 Carotenoid biosynthesis protein Glycos_transf_2 PF00535.26 EON32195.1 - 1.6e-11 44.3 0.0 2.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32195.1 - 1.4e-08 34.9 0.2 3.6e-08 33.6 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EON32195.1 - 3.6e-08 33.1 0.0 5.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 EON32195.1 - 0.17 12.4 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Amino_oxidase PF01593.24 EON32196.1 - 1.1e-26 94.2 0.1 2.8e-26 92.9 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EON32196.1 - 3.6e-13 49.5 0.1 1.1e-12 48.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON32196.1 - 3.7e-10 39.9 8.2 8.5e-06 25.6 2.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON32196.1 - 1.9e-06 27.4 0.2 0.00011 21.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32196.1 - 1.2e-05 25.7 0.6 0.00079 19.9 1.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON32196.1 - 3e-05 23.3 1.9 6.2e-05 22.2 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EON32196.1 - 0.0005 18.9 0.7 0.00074 18.3 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EON32196.1 - 0.0029 16.9 0.6 0.0044 16.3 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EON32196.1 - 0.056 12.5 0.3 0.11 11.6 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EON32196.1 - 0.069 12.2 0.9 0.1 11.7 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EON32196.1 - 0.074 12.3 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EON32196.1 - 0.085 12.7 0.7 0.13 12.1 0.7 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EON32196.1 - 0.12 12.1 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EON32196.1 - 0.12 11.6 0.9 0.18 11.1 0.9 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EON32196.1 - 0.19 11.1 2.7 0.26 10.6 2.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 EON32196.1 - 0.21 10.0 0.1 0.32 9.4 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON32196.1 - 0.21 10.8 0.2 0.33 10.2 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON32196.1 - 0.22 11.5 1.5 0.68 9.9 0.6 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 EON32196.1 - 0.33 9.7 0.0 0.44 9.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family PQQ_2 PF13360.6 EON32199.1 - 1.3e-07 31.5 13.0 0.041 13.5 0.0 4.2 1 1 1 4 4 4 4 PQQ-like domain PQQ PF01011.21 EON32199.1 - 1.8e-05 24.4 0.0 0.7 9.9 0.0 4.0 4 0 0 4 4 4 2 PQQ enzyme repeat Inhibitor_I42 PF09394.10 EON32199.1 - 0.057 13.8 0.2 0.17 12.3 0.2 1.8 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 SpoU_sub_bind PF08032.12 EON32200.1 - 0.047 14.0 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Amino_oxidase PF01593.24 EON32202.1 - 2.2e-22 80.0 0.7 7.4e-22 78.2 0.7 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EON32202.1 - 5.9e-19 68.1 0.1 1.6e-18 66.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON32202.1 - 2.9e-13 50.1 0.4 6.4e-13 49.0 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON32202.1 - 3.1e-07 30.1 0.0 1.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON32202.1 - 1.1e-06 28.1 1.1 0.00011 21.5 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32202.1 - 2.2e-06 28.1 0.5 0.00051 20.6 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON32202.1 - 5.5e-06 25.7 3.3 3.2e-05 23.2 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON32202.1 - 3.9e-05 22.5 0.2 0.00029 19.6 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EON32202.1 - 0.0002 20.7 0.7 0.00047 19.5 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EON32202.1 - 0.00084 18.3 1.8 0.0024 16.8 0.3 2.0 2 0 0 2 2 2 1 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 EON32202.1 - 0.002 17.8 0.1 0.036 13.6 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 EON32202.1 - 0.002 17.3 1.3 0.0028 16.8 1.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EON32202.1 - 0.0027 17.0 0.2 0.0048 16.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON32202.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EON32202.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EON32202.1 - 0.03 14.2 0.8 0.045 13.6 0.8 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EON32202.1 - 0.16 12.4 0.0 1 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding MCRA PF06100.11 EON32202.1 - 0.19 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 EON32202.1 - 0.27 10.5 0.0 0.53 9.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SQS_PSY PF00494.19 EON32203.1 - 2e-34 119.3 3.1 6.4e-33 114.4 3.1 2.1 1 1 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.28 EON32204.1 - 1.7e-13 50.7 0.1 2.4e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain CDP-OH_P_transf PF01066.21 EON32205.1 - 1.5e-08 35.3 3.0 1.5e-08 35.3 3.0 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3464 PF11947.8 EON32205.1 - 0.22 11.3 1.2 0.5 10.1 0.1 2.0 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 ACC_epsilon PF13822.6 EON32205.1 - 8.3 7.2 13.7 0.18 12.5 1.8 3.5 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Virul_fac_BrkB PF03631.15 EON32206.1 - 3.9e-19 69.3 22.1 4.5e-19 69.1 22.1 1.0 1 0 0 1 1 1 1 Virulence factor BrkB LysE PF01810.18 EON32207.1 - 5.2e-38 130.4 13.0 6.3e-38 130.2 13.0 1.0 1 0 0 1 1 1 1 LysE type translocator TetR_N PF00440.23 EON32208.1 - 2.9e-17 62.2 0.1 2.9e-17 62.2 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EON32208.1 - 2.5e-06 27.7 0.8 4.3e-06 26.9 0.8 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 EON32208.1 - 0.00015 21.9 1.8 0.00031 20.9 1.4 1.8 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain ABC2_membrane_3 PF12698.7 EON32209.1 - 9.2e-05 21.7 8.3 0.0012 18.0 0.0 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein HTH_1 PF00126.27 EON32210.1 - 1.4e-15 57.0 1.5 3.3e-15 55.8 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EON32210.1 - 6.6e-13 48.5 6.8 3e-12 46.4 4.9 2.0 2 0 0 2 2 2 1 LysR substrate binding domain HTH_30 PF13556.6 EON32210.1 - 0.00057 19.6 0.4 0.0012 18.6 0.4 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 EON32210.1 - 0.0007 19.4 0.6 0.002 18.0 0.6 1.8 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 EON32210.1 - 0.0053 16.8 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 EON32210.1 - 0.0091 16.0 0.8 0.055 13.5 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain P22_Cro PF14549.6 EON32210.1 - 0.011 15.6 0.1 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro HTH_24 PF13412.6 EON32210.1 - 0.021 14.3 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 EON32211.1 - 2.9e-17 62.7 88.4 2.8e-16 59.4 53.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EON32211.1 - 3.7e-14 52.0 36.6 4.7e-14 51.7 36.6 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Ku PF02735.16 EON32212.1 - 8.6e-38 130.1 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain HC2 PF07382.11 EON32212.1 - 0.0006 19.9 23.3 0.001 19.2 23.3 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Pneumo_att_G PF05539.11 EON32212.1 - 2.2 7.8 9.5 2.9 7.4 9.5 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SRP-alpha_N PF04086.13 EON32212.1 - 3.6 7.4 17.7 5.4 6.9 17.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HTH_5 PF01022.20 EON32215.1 - 0.039 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LexA_DNA_bind PF01726.16 EON32215.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 LexA DNA binding domain LigD_N PF13298.6 EON32216.1 - 3.5e-39 133.3 0.1 8.8e-39 132.0 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase Ligase (LigD) DNA_ligase_A_M PF01068.21 EON32216.1 - 1e-29 103.7 0.0 3.3e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EON32216.1 - 6.4e-25 87.6 0.0 2.4e-24 85.8 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EON32216.1 - 0.00061 20.1 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EON32216.1 - 0.11 12.5 0.0 0.7 10.0 0.0 2.2 1 1 0 1 1 1 0 DNA ligase OB-like domain DNA_primase_S PF01896.19 EON32216.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 DNA primase small subunit DLH PF01738.18 EON32217.1 - 3.8e-34 118.1 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EON32217.1 - 3.1e-05 23.6 0.3 0.013 14.9 0.1 2.4 2 1 1 3 3 3 2 Prolyl oligopeptidase family BAAT_C PF08840.11 EON32217.1 - 0.0096 15.9 0.1 0.05 13.5 0.0 1.9 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EON32217.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EON32217.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EON32217.1 - 0.016 14.8 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 EON32217.1 - 0.1 12.1 0.2 0.1 12.1 0.2 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase AXE1 PF05448.12 EON32217.1 - 0.12 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) adh_short_C2 PF13561.6 EON32218.1 - 0.035 13.7 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PrsW-protease PF13367.6 EON32219.1 - 4.6e-38 130.6 17.6 4.6e-38 130.6 17.6 2.0 2 0 0 2 2 2 1 PrsW family intramembrane metalloprotease DUF1418 PF07214.12 EON32219.1 - 0.76 9.7 3.9 0.43 10.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF3093 PF11292.8 EON32219.1 - 3.8 7.8 13.8 7.2 6.9 5.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) MFS_1 PF07690.16 EON32221.1 - 1e-51 176.0 45.2 1e-51 176.0 45.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32221.1 - 1.7e-13 50.2 35.5 1.5e-11 43.9 13.1 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EON32221.1 - 9.8e-08 30.9 25.0 1.4e-07 30.4 25.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 EON32221.1 - 0.00062 18.5 3.4 0.00062 18.5 3.4 2.7 3 1 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_2 PF13347.6 EON32221.1 - 0.0016 17.1 8.5 0.0016 17.1 8.5 3.1 1 1 0 2 2 2 2 MFS/sugar transport protein DUF5504 PF17608.2 EON32221.1 - 5.5 7.1 10.1 3.8 7.6 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5504) MarR PF01047.22 EON32222.1 - 1.4e-11 44.1 0.0 2.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON32222.1 - 2.6e-11 43.2 0.6 5.6e-11 42.2 0.3 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EON32222.1 - 3.6e-08 33.8 0.0 5.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 EON32222.1 - 2.1e-06 27.5 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EON32222.1 - 7.9e-06 25.6 0.4 7.9e-06 25.6 0.4 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EON32222.1 - 2.3e-05 24.3 0.4 7e-05 22.8 0.4 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EON32222.1 - 0.00025 20.9 0.2 0.00061 19.7 0.1 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 EON32222.1 - 0.00099 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EON32222.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding RP-C PF03428.13 EON32222.1 - 0.0032 17.1 0.2 0.0079 15.9 0.1 1.7 1 1 0 1 1 1 1 Replication protein C N-terminal domain Fe_dep_repress PF01325.19 EON32222.1 - 0.0063 16.7 0.0 0.0094 16.1 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 EON32222.1 - 0.0064 16.7 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain Rrf2 PF02082.20 EON32222.1 - 0.011 16.0 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator HTH_36 PF13730.6 EON32222.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 EON32222.1 - 0.12 12.2 1.9 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 EON32222.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Metallophos PF00149.28 EON32223.1 - 7.1e-16 59.3 0.0 1.6e-15 58.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON32223.1 - 6e-10 39.6 0.1 5.1e-09 36.5 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EON32223.1 - 0.0076 15.6 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily Sulfate_transp PF00916.20 EON32224.1 - 1.8e-65 221.2 31.9 2.5e-65 220.7 31.9 1.2 1 0 0 1 1 1 1 Sulfate permease family Pro_CA PF00484.19 EON32224.1 - 5.5e-41 140.4 0.0 9.1e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase MFS_MOT1 PF16983.5 EON32224.1 - 2.7e-06 27.8 6.6 2.7e-06 27.8 6.6 3.9 2 1 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF218 PF02698.17 EON32225.1 - 2.6e-22 79.2 0.3 4.2e-22 78.6 0.3 1.3 1 0 0 1 1 1 1 DUF218 domain DoxX_2 PF13564.6 EON32226.1 - 1.6e-13 50.7 10.3 2e-13 50.3 10.3 1.1 1 0 0 1 1 1 1 DoxX-like family Phage_holin_3_3 PF16083.5 EON32226.1 - 0.0098 16.0 1.6 0.23 11.6 1.6 2.3 2 0 0 2 2 2 1 LydA holin phage, holin superfamily III F420H2_quin_red PF04075.14 EON32227.1 - 9.4e-26 90.5 0.5 1.2e-25 90.2 0.5 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase PNTB PF02233.16 EON32228.1 - 3.2e-171 570.3 26.2 3.7e-171 570.1 26.2 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit NDUF_B12 PF08122.12 EON32228.1 - 2.9 8.0 6.2 1.4 9.0 0.1 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family PNTB_4TM PF12769.7 EON32229.1 - 5.5e-32 110.1 6.3 6.5e-32 109.8 6.3 1.0 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_C PF01262.21 EON32230.1 - 4.6e-66 222.2 2.4 7.2e-66 221.5 2.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EON32230.1 - 2.9e-39 134.5 0.1 6.9e-39 133.3 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 EON32230.1 - 3.4e-05 23.3 0.0 0.0056 16.1 0.0 2.3 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EON32230.1 - 0.0052 17.0 0.4 0.024 14.8 0.2 2.2 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 EON32230.1 - 0.01 15.8 1.9 0.025 14.5 0.6 2.4 3 1 0 3 3 3 0 Zinc-binding dehydrogenase Radical_SAM PF04055.21 EON32230.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 Radical SAM superfamily TetR_N PF00440.23 EON32231.1 - 8.9e-16 57.4 1.1 2.1e-15 56.2 0.0 2.2 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 EON32231.1 - 5.8e-10 39.1 4.6 5.8e-10 39.1 4.6 1.5 2 0 0 2 2 2 1 MftR C-terminal domain HTH_23 PF13384.6 EON32231.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 EON32231.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase AbiEi_4 PF13338.6 EON32231.1 - 0.042 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_11 PF08279.12 EON32231.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 HTH domain Aldo_ket_red PF00248.21 EON32232.1 - 4.7e-72 242.7 0.0 5.3e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 EON32233.1 - 1.2e-59 201.7 0.3 1.6e-59 201.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON32233.1 - 1.6e-44 151.7 0.0 2.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON32233.1 - 1.5e-14 54.3 0.2 2.1e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EON32233.1 - 0.0019 18.2 0.2 0.0038 17.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EON32233.1 - 0.0044 16.5 0.1 0.068 12.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ParD_antitoxin PF03693.14 EON32233.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH AdoHcyase_NAD PF00670.21 EON32233.1 - 0.017 15.2 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 EON32233.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 EON32233.1 - 0.12 12.2 0.5 0.89 9.3 1.2 2.1 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Oxidored_molyb PF00174.19 EON32234.1 - 1.7e-37 128.7 0.1 6.2e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Big_7 PF17957.1 EON32234.1 - 1.9e-05 25.3 0.1 7.4e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 Bacterial Ig domain Mo-co_dimer PF03404.16 EON32234.1 - 0.057 13.4 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF4131 PF13567.6 EON32234.1 - 0.56 9.8 4.2 2.1 8.0 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MerC PF03203.14 EON32234.1 - 3.7 8.0 8.5 0.25 11.8 2.8 2.0 2 1 0 2 2 2 0 MerC mercury resistance protein FAD_binding_2 PF00890.24 EON32235.1 - 3.9e-48 164.6 1.3 4.8e-48 164.3 1.3 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EON32235.1 - 3.9e-11 43.1 6.3 2.8e-10 40.3 6.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON32235.1 - 1.8e-09 36.9 2.1 0.00038 19.3 2.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EON32235.1 - 1.6e-08 34.1 1.2 5.9e-07 29.0 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON32235.1 - 7.3e-08 32.2 7.0 1.3e-06 28.0 7.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON32235.1 - 0.00016 21.0 1.5 0.00016 21.0 1.5 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EON32235.1 - 0.00028 20.1 4.1 0.01 14.9 3.4 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EON32235.1 - 0.0014 18.8 4.4 0.0047 17.1 4.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SQHop_cyclase_C PF13243.6 EON32235.1 - 0.0089 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain AlaDh_PNT_C PF01262.21 EON32235.1 - 0.012 14.9 0.8 0.025 13.9 0.8 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EON32235.1 - 0.029 13.7 0.3 0.029 13.7 0.3 2.2 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EON32235.1 - 0.13 11.5 2.5 0.6 9.3 1.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EON32235.1 - 0.26 11.9 2.0 27 5.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E1-E2_ATPase PF00122.20 EON32236.1 - 5.8e-47 159.5 7.0 1.4e-46 158.3 7.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EON32236.1 - 1.6e-39 136.4 6.1 3.9e-39 135.1 6.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EON32236.1 - 3.1e-12 46.7 0.1 9.3e-12 45.2 0.1 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EON32236.1 - 6.9e-05 22.7 0.6 0.00011 22.0 0.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EON32238.1 - 1e-13 51.5 0.3 1.2e-13 51.3 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Spore_YhcN_YlaJ PF09580.10 EON32238.1 - 0.022 14.9 0.2 0.023 14.8 0.2 1.0 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Trns_repr_metal PF02583.17 EON32239.1 - 1.6e-31 108.5 3.0 1.8e-31 108.3 3.0 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor Abhydrolase_1 PF00561.20 EON32241.1 - 5.1e-22 78.8 0.8 3.8e-17 62.8 0.7 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON32241.1 - 2.8e-17 64.1 23.8 4.6e-17 63.4 23.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON32241.1 - 2.1e-08 33.7 0.3 5.5e-08 32.4 0.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FAD_binding_2 PF00890.24 EON32242.1 - 1.3e-79 268.2 16.5 1.3e-79 268.2 16.5 1.4 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 EON32242.1 - 2.2e-10 40.6 1.8 2e-08 34.3 1.8 2.2 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EON32242.1 - 4.2e-09 36.0 4.4 2.6e-05 23.6 0.8 3.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON32242.1 - 2.2e-06 26.7 0.4 0.00051 18.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EON32242.1 - 1.1e-05 25.1 2.3 2.8e-05 23.7 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON32242.1 - 2.5e-05 24.4 1.8 6.5e-05 23.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON32242.1 - 8.9e-05 21.8 0.5 0.00026 20.3 0.2 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EON32242.1 - 0.0002 20.6 0.1 0.00045 19.4 0.1 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EON32242.1 - 0.00027 20.6 11.0 0.00027 20.6 11.0 2.7 2 2 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EON32242.1 - 0.0012 18.2 0.4 0.0031 16.8 0.4 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON32242.1 - 0.0027 16.8 3.3 0.016 14.3 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EON32242.1 - 0.015 14.5 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON32243.1 - 1.7e-37 129.8 5.7 2.2e-37 129.4 5.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 EON32243.1 - 3.2e-07 30.2 0.1 7.4e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 EON32243.1 - 1.6e-05 25.0 2.3 4.4e-05 23.6 2.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON32243.1 - 7.9e-05 21.9 8.0 0.00036 19.7 8.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON32243.1 - 0.00019 20.8 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON32243.1 - 0.00031 20.1 1.1 0.00055 19.3 1.1 1.4 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EON32243.1 - 0.00058 19.3 0.8 0.38 10.0 0.5 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EON32243.1 - 0.00068 18.4 0.2 0.91 8.2 0.7 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 EON32243.1 - 0.0023 17.2 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON32243.1 - 0.028 13.8 1.5 0.056 12.8 1.5 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EON32243.1 - 0.029 13.6 0.2 0.052 12.8 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EON32243.1 - 0.044 14.3 0.3 0.19 12.3 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON32243.1 - 0.069 13.1 0.7 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EON32243.1 - 0.38 9.8 1.2 2 7.4 1.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.25 EON32244.1 - 1.5e-44 151.8 1.8 1.9e-44 151.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32244.1 - 3.4e-30 105.3 2.4 4.6e-30 104.9 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32244.1 - 3.3e-11 43.4 1.4 6.3e-11 42.5 1.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EON32244.1 - 0.012 15.1 0.6 0.024 14.1 0.6 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amino_oxidase PF01593.24 EON32245.1 - 3.9e-14 52.8 5.1 2.2e-12 47.0 5.1 2.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EON32245.1 - 1.3e-10 41.4 5.5 7.1e-06 25.8 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON32245.1 - 6.3e-10 39.1 0.0 2.7e-09 37.1 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON32245.1 - 1.7e-07 30.7 0.3 0.0033 16.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON32245.1 - 3.7e-07 29.2 0.0 0.00011 21.1 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EON32245.1 - 7.4e-07 28.6 9.5 9.1e-06 25.0 0.9 2.4 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EON32245.1 - 1.1e-05 25.0 2.2 0.00011 21.8 1.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON32245.1 - 4.1e-05 24.0 0.9 0.12 13.0 0.2 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON32245.1 - 0.00013 21.2 0.4 0.0012 18.0 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON32245.1 - 0.0006 19.8 1.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EON32245.1 - 0.0016 17.7 1.2 0.011 15.0 0.2 2.4 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EON32245.1 - 0.002 17.4 0.3 0.0037 16.5 0.3 1.4 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 EON32245.1 - 0.084 12.5 0.2 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EON32245.1 - 0.15 10.9 2.2 0.97 8.2 0.4 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EON32245.1 - 0.16 11.0 0.4 0.3 10.1 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EON32245.1 - 0.17 11.1 0.1 0.34 10.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polyketide_cyc2 PF10604.9 EON32246.1 - 2.1e-07 31.3 0.8 2.6e-07 31.0 0.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FMN_red PF03358.15 EON32247.1 - 4.2e-19 68.8 0.0 5.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON32247.1 - 0.00048 19.9 0.0 0.0017 18.1 0.0 1.8 2 1 0 2 2 2 1 Flavodoxin-like fold baeRF_family2 PF18844.1 EON32250.1 - 1.7e-37 128.7 4.4 1.7e-37 128.7 4.4 1.8 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 2 baeRF_family10 PF18854.1 EON32250.1 - 5e-10 39.8 0.2 1e-09 38.8 0.2 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EON32250.1 - 0.00046 20.5 0.9 0.0014 18.9 0.9 1.9 1 1 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Host_attach PF10116.9 EON32250.1 - 0.00049 20.7 0.2 0.0013 19.4 0.0 1.8 2 0 0 2 2 2 1 Protein required for attachment to host cells ADH_N PF08240.12 EON32251.1 - 2.9e-29 101.1 1.4 9e-29 99.6 1.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON32251.1 - 5.6e-17 61.9 0.0 9.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON32251.1 - 3.2e-05 25.0 0.0 5.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON32251.1 - 0.00041 19.7 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EON32251.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EON32251.1 - 0.06 13.8 0.0 0.15 12.5 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 EON32251.1 - 0.62 9.4 2.3 36 3.6 3.1 2.2 1 1 1 2 2 2 0 ThiF family NADH_4Fe-4S PF10589.9 EON32251.1 - 2.7 8.1 4.6 6.5 6.9 4.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ABC1 PF03109.16 EON32252.1 - 1.3e-29 102.8 0.0 2.7e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EON32252.1 - 8.4e-06 25.9 3.2 6.5e-05 23.0 1.8 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EON32252.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EON32252.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH_6_hur PF04655.14 EON32252.1 - 0.033 13.6 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase HMG_box_2 PF09011.10 EON32252.1 - 0.21 12.2 0.0 0.37 11.4 0.0 1.3 1 0 0 1 1 1 0 HMG-box domain Haspin_kinase PF12330.8 EON32252.1 - 0.26 10.2 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PorA PF11271.8 EON32253.1 - 2.1e-89 299.8 0.9 2.5e-89 299.5 0.9 1.0 1 0 0 1 1 1 1 Porin PorA DUF2370 PF10176.9 EON32253.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Gram_pos_anchor PF00746.21 EON32253.1 - 0.064 13.2 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_holin_3_6 PF07332.11 EON32253.1 - 0.26 11.3 1.0 0.87 9.6 0.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Esterase PF00756.20 EON32254.1 - 6.7e-30 104.6 0.5 1.3e-29 103.6 0.5 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EON32254.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EON32254.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family YjbE PF11106.8 EON32254.1 - 0.17 12.1 3.6 1.7 8.9 3.5 2.5 2 1 0 2 2 2 0 Exopolysaccharide production protein YjbE Amidase PF01425.21 EON32255.1 - 5.2e-88 296.0 0.5 4.2e-86 289.7 0.5 2.8 1 1 0 1 1 1 1 Amidase FAD_binding_2 PF00890.24 EON32256.1 - 7.7e-108 361.2 1.0 8.7e-108 361.1 1.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EON32256.1 - 7.8e-08 32.4 0.4 2.8e-07 30.7 0.1 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON32256.1 - 2.2e-05 24.2 5.5 0.00015 21.5 5.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON32256.1 - 2.9e-05 23.5 0.3 5.9e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EON32256.1 - 0.0001 21.7 0.2 0.00065 19.0 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON32256.1 - 0.00028 20.2 0.4 0.0011 18.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EON32256.1 - 0.00071 18.4 0.2 0.00071 18.4 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EON32256.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EON32256.1 - 0.0023 17.1 0.3 0.0023 17.1 0.3 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON32256.1 - 0.0069 16.4 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EON32256.1 - 0.009 16.6 0.5 0.09 13.3 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON32256.1 - 0.056 12.7 0.2 0.15 11.3 0.2 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON32256.1 - 0.064 12.3 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EON32256.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EON32256.1 - 0.19 11.3 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Dyp_perox PF04261.12 EON32257.1 - 6.7e-87 291.5 0.0 9.7e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 Dyp-type peroxidase family Linocin_M18 PF04454.12 EON32258.1 - 3.9e-95 318.0 0.0 4.4e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Encapsulating protein for peroxidase Phage_capsid PF05065.13 EON32258.1 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Phage capsid family ABC_membrane PF00664.23 EON32259.1 - 1.2e-45 156.3 9.3 1.5e-45 156.0 9.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON32259.1 - 8.1e-28 97.6 0.0 1.2e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON32259.1 - 6.6e-06 25.7 0.1 0.002 17.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EON32259.1 - 8.5e-05 21.9 0.1 0.004 16.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 EON32259.1 - 0.00096 18.8 0.5 0.016 14.9 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON32259.1 - 0.0017 18.8 0.1 0.0034 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EON32259.1 - 0.034 14.6 0.7 0.056 13.9 0.7 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EON32259.1 - 0.11 12.6 2.0 0.19 11.8 2.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_membrane PF00664.23 EON32260.1 - 2.1e-57 194.9 2.6 2.8e-57 194.5 2.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON32260.1 - 5.7e-29 101.4 0.0 1.6e-28 99.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 EON32260.1 - 4.3e-05 23.8 0.8 0.00064 20.0 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EON32260.1 - 7.9e-05 23.1 0.1 0.00045 20.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EON32260.1 - 0.0005 19.8 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain EI24 PF07264.11 EON32260.1 - 0.00076 19.8 2.5 0.0066 16.7 2.3 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SMC_N PF02463.19 EON32260.1 - 0.00089 18.7 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 EON32260.1 - 0.0012 19.3 0.0 0.012 16.0 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EON32260.1 - 0.0027 18.2 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON32260.1 - 0.0031 17.4 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 EON32260.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_membrane_2 PF06472.15 EON32260.1 - 0.018 14.5 0.4 0.035 13.5 0.4 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 MMR_HSR1 PF01926.23 EON32260.1 - 0.02 14.9 0.0 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 EON32260.1 - 0.021 15.2 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON32260.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EON32260.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EON32260.1 - 0.047 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EON32260.1 - 0.054 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EON32260.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 EON32260.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 EON32260.1 - 0.079 12.8 0.4 2.5 7.8 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 EON32260.1 - 0.079 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 EON32260.1 - 0.09 12.7 0.2 0.22 11.4 0.0 1.7 2 0 0 2 2 1 0 NTPase NACHT PF05729.12 EON32260.1 - 0.12 12.3 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_35 PF14516.6 EON32260.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.6 EON32260.1 - 0.13 12.3 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EON32260.1 - 0.19 11.5 0.2 1.8 8.3 0.2 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase RibD_C PF01872.17 EON32261.1 - 6.9e-25 88.0 0.0 1.3e-24 87.2 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain adh_short PF00106.25 EON32262.1 - 4.1e-38 130.8 0.0 5.2e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32262.1 - 1.8e-30 106.2 0.6 2.3e-30 105.9 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32262.1 - 3.5e-08 33.6 2.0 8.7e-08 32.3 2.0 1.6 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 EON32262.1 - 8e-05 22.8 2.0 0.008 16.3 3.2 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3Beta_HSD PF01073.19 EON32262.1 - 0.0041 16.2 0.1 0.0067 15.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EON32262.1 - 0.0052 16.7 1.4 0.0092 15.9 1.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EON32262.1 - 0.017 14.6 2.6 0.037 13.5 2.6 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EON32262.1 - 0.018 15.6 0.8 0.033 14.8 0.8 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 EON32262.1 - 0.024 14.3 1.5 0.029 13.9 1.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EON32262.1 - 0.034 14.4 0.5 0.077 13.3 0.5 1.6 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 EON32262.1 - 0.05 13.2 0.8 0.1 12.1 0.8 1.5 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 EON32262.1 - 0.07 13.1 1.7 0.21 11.6 1.7 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 EON32262.1 - 0.16 11.4 0.6 0.25 10.7 0.2 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PALP PF00291.25 EON32262.1 - 0.89 8.9 5.9 5.9 6.2 5.9 2.1 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PTE PF02126.18 EON32263.1 - 4.7e-90 302.0 0.0 5.3e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family LexA_DNA_bind PF01726.16 EON32263.1 - 0.14 11.9 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 LexA DNA binding domain TAL_effector PF03377.13 EON32263.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 TAL effector repeat Transp_cyt_pur PF02133.15 EON32264.1 - 4.6e-43 147.6 44.7 5.3e-43 147.4 44.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_S9 PF00326.21 EON32265.1 - 1.2e-10 41.2 0.1 1e-09 38.2 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EON32265.1 - 5.4e-09 35.7 0.1 0.0003 20.1 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EON32265.1 - 6.5e-07 29.4 0.9 1.8e-06 27.9 0.9 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EON32265.1 - 3.4e-06 26.7 1.6 0.01 15.4 0.3 2.6 2 1 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 EON32265.1 - 4.1e-05 23.4 0.2 0.0046 16.6 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EON32265.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1100 PF06500.11 EON32265.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) ASH PF15780.5 EON32266.1 - 0.13 12.5 0.1 0.68 10.2 0.0 2.1 1 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF2510 PF10708.9 EON32268.1 - 8.6e-10 38.2 10.7 1.1e-09 37.9 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) DUF2749 PF10907.8 EON32268.1 - 0.11 12.7 1.6 0.11 12.6 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) BIV_Env PF05858.12 EON32268.1 - 0.21 9.8 0.2 0.23 9.6 0.2 1.0 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Pilin_N PF07790.11 EON32268.1 - 1.7 9.6 5.0 1.9 9.5 5.0 1.3 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF72 PF01904.18 EON32269.1 - 6.5e-58 196.4 0.3 7.4e-58 196.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 TPP_enzyme_N PF02776.18 EON32269.1 - 0.17 11.5 0.1 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FMN_red PF03358.15 EON32270.1 - 1.6e-13 50.7 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON32270.1 - 3.7e-07 30.1 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EON32270.1 - 2.9e-06 27.6 0.0 0.0073 16.5 0.0 2.2 2 0 0 2 2 2 2 Flavodoxin domain Flavodoxin_1 PF00258.25 EON32270.1 - 0.0017 18.5 0.1 0.0037 17.5 0.1 1.5 1 1 0 1 1 1 1 Flavodoxin FBP_C PF16571.5 EON32271.1 - 1.5e-55 187.0 0.0 1.7e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 FBP C-terminal treble-clef zinc-finger Ogr_Delta PF04606.12 EON32271.1 - 0.039 13.9 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger F420H2_quin_red PF04075.14 EON32272.1 - 2.1e-37 128.1 0.1 2.4e-37 127.9 0.1 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase RibD_C PF01872.17 EON32273.1 - 1.6e-22 80.3 0.0 2.3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain DUF4431 PF14485.6 EON32273.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) DUF309 PF03745.14 EON32274.1 - 3.5e-19 68.2 0.1 4.7e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF309) TPR_14 PF13428.6 EON32274.1 - 0.026 15.3 6.1 1 10.4 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EON32274.1 - 0.046 13.8 0.1 2.6 8.4 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EON32274.1 - 6.1 7.8 14.5 1.1 10.1 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SWI2_SNF2 PF18766.1 EON32276.1 - 4e-71 239.3 0.0 7.5e-71 238.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF3387 PF11867.8 EON32276.1 - 1.9e-30 106.4 1.0 3.5e-30 105.5 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) HSDR_N PF04313.14 EON32276.1 - 1.4e-29 103.4 0.0 1.3e-28 100.3 0.0 2.4 3 0 0 3 3 3 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 EON32276.1 - 9.4e-17 61.5 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methylase_S PF01420.19 EON32277.1 - 9.8e-24 84.4 0.0 8.7e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.16 EON32278.1 - 3.7e-82 276.1 0.0 4.9e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 EON32278.1 - 1.4e-17 64.6 0.0 3.1e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 HsdM N-terminal domain MTS PF05175.14 EON32278.1 - 2.2e-06 27.4 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EON32278.1 - 0.00042 20.1 0.0 0.00096 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EON32278.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 EON32278.1 - 0.042 13.3 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_25 PF13649.6 EON32278.1 - 0.17 12.6 0.0 0.66 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF3662 PF12401.8 EON32279.1 - 1.2e-33 115.9 0.0 1.7e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2662) FHA PF00498.26 EON32279.1 - 2.3e-15 56.7 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EON32279.1 - 3.1e-14 53.1 0.1 6.3e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Yop-YscD_cpl PF16697.5 EON32280.1 - 4.3e-15 55.8 0.0 5.4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 EON32280.1 - 1.5e-14 54.1 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 FHA domain PP2C_2 PF13672.6 EON32281.1 - 6.3e-13 48.8 0.4 2.5e-12 46.9 0.5 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 EON32281.1 - 1.5e-09 37.9 0.0 9.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Pex14_N PF04695.13 EON32281.1 - 0.78 10.4 12.8 0.8 10.3 0.1 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FTSW_RODA_SPOVE PF01098.19 EON32282.1 - 1.4e-87 294.0 23.0 1.4e-87 294.0 23.0 1.4 2 0 0 2 2 2 1 Cell cycle protein Transpeptidase PF00905.22 EON32283.1 - 7.2e-60 202.8 0.1 9.6e-60 202.3 0.1 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Pkinase PF00069.25 EON32284.1 - 5.8e-45 153.7 0.0 7.5e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON32284.1 - 2.5e-31 108.9 0.0 3.3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON32284.1 - 4.7e-06 26.7 0.6 0.021 14.7 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EON32284.1 - 0.0047 16.3 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EON32284.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EON32284.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EON32284.1 - 0.19 10.6 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF3040 PF11239.8 EON32284.1 - 0.33 11.2 4.9 15 6.0 1.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) RskA PF10099.9 EON32284.1 - 4 7.7 25.9 4.4 7.6 13.3 2.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Pkinase PF00069.25 EON32285.1 - 3.6e-51 174.1 0.0 4.9e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PASTA PF03793.19 EON32285.1 - 8.1e-46 153.7 13.4 5e-14 51.9 1.4 4.3 4 0 0 4 4 4 4 PASTA domain Pkinase_Tyr PF07714.17 EON32285.1 - 1.9e-35 122.4 0.0 2.6e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON32285.1 - 1.3e-09 38.3 0.7 0.00047 20.2 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON32285.1 - 0.002 17.0 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EON32285.1 - 0.0081 15.2 0.1 0.016 14.3 0.0 1.4 2 0 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.14 EON32285.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EON32285.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Arabino_trans_N PF17689.1 EON32285.1 - 0.022 14.9 1.1 0.053 13.7 1.1 1.7 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain Kinase-like PF14531.6 EON32285.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 EON32285.1 - 0.12 12.5 0.1 2.1 8.5 0.0 2.5 2 1 1 3 3 3 0 ABC1 family Haspin_kinase PF12330.8 EON32285.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain GATase PF00117.28 EON32286.1 - 1.1e-50 172.1 0.0 1.2e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EON32286.1 - 6.7e-13 48.9 0.3 1.2e-11 44.9 0.2 2.4 1 1 1 2 2 2 1 Peptidase C26 CrgA PF06781.12 EON32287.1 - 1.7e-35 120.9 2.1 2e-35 120.7 2.1 1.0 1 0 0 1 1 1 1 Cell division protein CrgA bPH_6 PF10756.9 EON32288.1 - 1.6e-07 31.3 8.4 9.3e-06 25.7 8.4 2.3 1 1 0 1 1 1 1 Bacterial PH domain Rhomboid PF01694.22 EON32289.1 - 1e-29 103.5 12.9 1e-29 103.5 12.9 1.8 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 EON32289.1 - 0.012 16.2 0.3 0.012 16.2 0.3 2.1 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF543 PF04418.12 EON32289.1 - 5.3 7.1 10.2 0.45 10.5 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF543) Pro_isomerase PF00160.21 EON32290.1 - 5.7e-46 156.7 0.0 6.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4190 PF13828.6 EON32293.1 - 8.7e-13 47.8 4.9 8.7e-13 47.8 4.9 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4190) Abhydrolase_9_N PF15420.6 EON32293.1 - 0.0044 17.1 0.8 0.0052 16.8 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus COX14 PF14880.6 EON32293.1 - 0.09 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DEC-1_N PF04625.13 EON32293.1 - 0.11 11.5 1.9 0.13 11.3 1.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PgaD PF13994.6 EON32293.1 - 4.1 7.5 6.4 6.4 6.8 4.1 2.0 1 1 1 2 2 2 0 PgaD-like protein Acyl-CoA_dh_M PF02770.19 EON32294.1 - 1.2e-10 41.4 0.0 2.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32294.1 - 2.9e-10 40.5 9.7 5.4e-10 39.7 9.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EON32294.1 - 0.0026 18.0 3.0 0.0048 17.1 3.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bac_luciferase PF00296.20 EON32295.1 - 6.7e-60 203.1 0.4 8.7e-60 202.8 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SBP_bac_5 PF00496.22 EON32296.1 - 3.2e-69 233.7 4.1 4.1e-69 233.4 4.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EON32297.1 - 2.4e-26 92.6 11.5 2.4e-26 92.6 11.5 2.3 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component MotA_ExbB PF01618.16 EON32297.1 - 0.17 11.6 0.2 0.17 11.6 0.2 1.8 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family BPD_transp_1 PF00528.22 EON32298.1 - 1.3e-22 80.5 13.6 1.3e-22 80.5 13.6 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EON32298.1 - 0.0027 17.7 6.9 0.0027 17.7 6.9 3.6 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 EON32299.1 - 1.3e-56 190.9 0.0 2.4e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON32299.1 - 3.6e-16 59.9 7.7 1.7e-06 28.1 0.1 4.1 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 EON32299.1 - 6.5e-15 55.4 0.0 8.4e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 EON32299.1 - 7.8e-09 35.9 6.2 0.004 17.4 0.7 3.8 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 EON32299.1 - 1.3e-06 28.0 1.1 0.15 11.5 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EON32299.1 - 3.9e-05 23.8 4.3 0.084 12.9 0.4 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 EON32299.1 - 0.00011 21.9 1.4 0.18 11.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EON32299.1 - 0.00039 20.2 0.3 0.97 9.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EON32299.1 - 0.00055 20.4 14.2 0.046 14.1 1.5 3.5 2 2 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EON32299.1 - 0.0017 17.8 0.8 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EON32299.1 - 0.0033 17.2 1.9 2.9 7.6 0.1 3.2 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_5 PF07728.14 EON32299.1 - 0.0068 16.4 0.1 4.1 7.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EON32299.1 - 0.0084 16.0 1.5 3.9 7.4 0.1 2.7 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.6 EON32299.1 - 0.012 15.7 1.0 6.5 6.9 0.0 3.4 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA PF00004.29 EON32299.1 - 0.013 15.9 0.1 3.4 8.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EON32299.1 - 0.023 15.2 0.6 1.2 9.6 0.3 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EON32299.1 - 0.032 13.6 0.2 6.2 6.2 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EON32299.1 - 0.043 13.7 0.2 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EON32299.1 - 0.045 13.3 0.3 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EON32299.1 - 0.047 13.8 1.2 10 6.2 0.1 3.2 2 2 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EON32299.1 - 0.05 13.8 3.4 11 6.2 0.9 3.3 3 1 0 3 3 3 0 AAA domain DUF3987 PF13148.6 EON32299.1 - 0.074 12.0 0.7 18 4.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Zeta_toxin PF06414.12 EON32299.1 - 0.08 12.2 0.8 1.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Herpes_ori_bp PF02399.15 EON32299.1 - 0.098 10.7 0.5 2.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Origin of replication binding protein AAA_18 PF13238.6 EON32299.1 - 0.1 13.1 0.1 12 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EON32299.1 - 0.1 11.7 1.3 6.8 5.8 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 EON32299.1 - 0.14 11.5 0.6 28 4.1 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 EON32299.1 - 0.15 12.4 0.9 14 6.1 0.1 2.3 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.16 EON32299.1 - 0.15 11.3 1.0 9.6 5.5 0.1 2.2 2 0 0 2 2 2 0 AIG1 family PRK PF00485.18 EON32299.1 - 0.21 11.3 4.2 2.7 7.7 0.5 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 EON32299.1 - 0.25 11.3 0.6 6.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.6 EON32299.1 - 0.3 9.7 0.4 8 5.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EON32299.1 - 0.37 9.7 1.5 0.42 9.5 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain Myosin_head PF00063.21 EON32299.1 - 0.4 8.8 3.0 2.3 6.3 0.1 2.0 2 0 0 2 2 2 0 Myosin head (motor domain) Hpr_kinase_C PF07475.12 EON32299.1 - 0.57 9.7 2.8 2.3 7.7 0.3 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain APS_kinase PF01583.20 EON32299.1 - 0.62 9.9 2.7 15 5.5 0.1 3.3 3 1 0 3 3 3 0 Adenylylsulphate kinase Pox_A32 PF04665.12 EON32299.1 - 0.81 9.1 2.0 25 4.2 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.17 EON32299.1 - 1.6 8.4 3.7 3 7.5 0.1 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EON32299.1 - 3.3 7.4 6.2 11 5.6 0.2 3.2 4 0 0 4 4 3 0 AAA domain MFS_1 PF07690.16 EON32300.1 - 4.1e-48 164.1 50.3 1.2e-41 142.8 32.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32300.1 - 9.2e-08 31.4 9.9 9.2e-08 31.4 9.9 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EON32300.1 - 0.00061 18.8 5.0 0.00061 18.8 5.0 2.4 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 EON32300.1 - 0.0015 17.1 6.7 0.0015 17.1 6.7 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 EON32300.1 - 2.6 6.2 15.8 0.62 8.3 0.7 3.4 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 EON32302.1 - 1.8e-24 86.3 0.0 2.2e-23 82.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32302.1 - 2.4e-18 66.6 0.0 2.3e-17 63.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32302.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON32302.1 - 0.011 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 EON32302.1 - 0.032 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DJ-1_PfpI PF01965.24 EON32303.1 - 2.3e-15 56.8 0.0 4.7e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EON32303.1 - 1.9e-14 53.8 0.0 7.4e-14 51.9 0.0 1.9 2 1 0 2 2 2 1 ThiJ/PfpI family-like DUF5568 PF17724.1 EON32303.1 - 0.036 13.9 0.0 1.6 8.5 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5568) Ribosomal_S18 PF01084.20 EON32304.1 - 1.1e-22 80.0 0.1 1.4e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Peptidase_C92 PF05708.12 EON32304.1 - 0.081 13.0 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Ribosomal_S14 PF00253.21 EON32305.1 - 1.5e-23 82.3 0.6 2.6e-23 81.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e AbiEi_4 PF13338.6 EON32305.1 - 3 8.1 8.2 3.8 7.7 0.7 2.6 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Ribosomal_L33 PF00471.20 EON32306.1 - 3.6e-15 56.1 0.0 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Ribosomal_L28 PF00830.19 EON32307.1 - 1.3e-23 82.9 0.7 1.3e-23 82.9 0.7 1.5 2 0 0 2 2 2 1 Ribosomal L28 family CobW_C PF07683.14 EON32308.1 - 6.8e-16 58.0 0.0 4.7e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.19 EON32308.1 - 7.8e-10 38.6 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L31 PF01197.18 EON32309.1 - 3.3e-29 100.9 0.1 3.8e-29 100.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 Pkinase PF00069.25 EON32310.1 - 7.6e-37 127.1 0.0 9.5e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON32310.1 - 4.2e-17 62.3 0.0 5.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON32310.1 - 4.6e-07 30.0 5.3 3.4e-05 23.9 0.9 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON32310.1 - 0.00062 18.6 0.0 0.00079 18.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EON32310.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3328 PF11807.8 EON32310.1 - 0.16 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) TetR_C_31 PF17940.1 EON32311.1 - 3.8e-23 81.7 2.7 3.8e-23 81.7 2.7 2.3 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32311.1 - 4.3e-07 29.6 0.1 2e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family PXA PF02194.15 EON32311.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 PXA domain RibD_C PF01872.17 EON32312.1 - 2.7e-12 46.9 0.0 3.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 EON32312.1 - 0.0031 17.2 0.0 0.0041 16.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase RmlD_sub_bind PF04321.17 EON32313.1 - 0.0024 17.0 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EON32313.1 - 0.0092 15.5 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cupin_2 PF07883.11 EON32314.1 - 1.4e-13 50.4 0.1 1.7e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EON32314.1 - 8.5e-07 29.0 0.3 1.1e-06 28.6 0.3 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EON32314.1 - 0.22 11.1 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Cupin AlbA_2 PF04326.14 EON32315.1 - 3.4e-15 56.4 0.0 5.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain HATPase_c_4 PF13749.6 EON32315.1 - 8.5e-10 38.6 0.0 2.7e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Putative ATP-dependent DNA helicase recG C-terminal HTH_5 PF01022.20 EON32315.1 - 4.5e-08 32.8 0.1 1.1e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EON32315.1 - 1.6e-07 30.8 0.1 0.0087 15.6 0.0 2.8 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EON32315.1 - 2.2e-07 31.3 0.2 1.1e-06 29.0 0.1 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 EON32315.1 - 2.1e-06 27.5 0.4 3.2e-05 23.8 0.2 2.3 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EON32315.1 - 3.3e-06 26.9 0.8 0.00064 19.6 0.1 2.7 2 0 0 2 2 2 1 MarR family HTH_29 PF13551.6 EON32315.1 - 3.9e-06 26.8 1.1 0.005 16.8 0.0 3.5 3 0 0 3 3 3 1 Winged helix-turn helix HTH_20 PF12840.7 EON32315.1 - 1.1e-05 25.4 1.1 4.1e-05 23.6 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 EON32315.1 - 0.00013 21.7 0.1 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_42 PF06224.12 EON32315.1 - 0.0005 19.7 0.3 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain Penicillinase_R PF03965.16 EON32315.1 - 0.0011 19.2 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Penicillinase repressor HTH_11 PF08279.12 EON32315.1 - 0.0015 18.4 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 HTH domain PaaX PF07848.12 EON32315.1 - 0.0019 18.4 0.4 0.02 15.1 0.1 2.5 2 0 0 2 2 2 1 PaaX-like protein RP-C PF03428.13 EON32315.1 - 0.016 14.9 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Replication protein C N-terminal domain TrmB PF01978.19 EON32315.1 - 0.025 14.4 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 EON32315.1 - 0.037 13.7 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) FaeA PF04703.12 EON32315.1 - 0.039 14.3 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 FaeA-like protein HTH_IclR PF09339.10 EON32315.1 - 0.04 13.7 1.8 0.077 12.8 0.3 2.4 2 0 0 2 2 1 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 EON32315.1 - 0.08 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 EON32315.1 - 0.14 12.3 0.4 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Replic_Relax PF13814.6 EON32315.1 - 0.14 12.2 0.5 0.49 10.4 0.2 2.1 1 1 0 2 2 2 0 Replication-relaxation GntR PF00392.21 EON32315.1 - 0.56 9.9 3.4 0.3 10.7 0.1 2.3 3 0 0 3 3 2 0 Bacterial regulatory proteins, gntR family DUF3566 PF12089.8 EON32316.1 - 7.8e-41 139.1 5.9 9.7e-41 138.8 5.9 1.1 1 0 0 1 1 1 1 Transmembrane domain of unknown function (DUF3566) DUF2189 PF09955.9 EON32316.1 - 0.16 12.2 3.6 0.24 11.6 3.6 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) DNA_topoisoIV PF00521.20 EON32317.1 - 5.9e-146 486.7 0.0 7.6e-146 486.3 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EON32317.1 - 1.5e-67 222.9 10.3 1e-11 44.1 0.1 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller SIS PF01380.22 EON32317.1 - 0.037 13.9 0.0 0.9 9.4 0.0 2.8 2 0 0 2 2 2 0 SIS domain Nnf1 PF03980.14 EON32317.1 - 0.078 13.4 1.6 0.16 12.3 1.6 1.6 1 0 0 1 1 1 0 Nnf1 DAO_C PF16901.5 EON32317.1 - 0.14 12.0 0.6 0.5 10.2 0.6 2.0 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase DNA_gyraseB PF00204.25 EON32318.1 - 2.9e-61 206.0 0.9 4.6e-61 205.3 0.9 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EON32318.1 - 1.1e-26 92.8 0.0 2.1e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EON32318.1 - 5.9e-20 71.8 0.0 1.7e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EON32318.1 - 3.2e-16 59.4 0.0 1.1e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EON32318.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DciA PF05258.12 EON32319.1 - 3.5e-25 88.2 0.3 5.3e-25 87.6 0.3 1.3 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA SMC_N PF02463.19 EON32320.1 - 2.4e-19 69.7 0.0 3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON32320.1 - 1.1e-09 39.1 0.0 1.5e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EON32320.1 - 1.9e-06 27.8 0.0 2.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EON32320.1 - 3.5e-05 23.8 0.6 0.00018 21.4 0.1 2.1 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EON32320.1 - 0.025 14.8 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EON32320.1 - 0.03 14.1 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EON32320.1 - 0.047 14.2 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF630 PF04783.12 EON32320.1 - 0.3 11.3 2.1 0.7 10.1 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF630) DNA_pol3_beta PF00712.19 EON32321.1 - 4.9e-44 149.3 0.0 7.7e-35 119.7 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 EON32321.1 - 2.4e-33 114.8 0.0 6.4e-31 107.0 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 EON32321.1 - 1.2e-32 112.3 0.0 1.1e-30 105.9 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase III beta subunit, C-terminal domain Bac_DnaA PF00308.18 EON32322.1 - 4.1e-102 340.6 0.0 6.6e-102 340.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 EON32322.1 - 6.4e-27 93.4 0.0 1.4e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 EON32322.1 - 2e-10 40.7 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EON32322.1 - 3.5e-05 24.2 0.0 0.00015 22.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON32322.1 - 0.00055 20.2 1.0 0.71 10.1 0.4 2.9 2 1 0 2 2 2 1 AAA domain DnaA_N PF11638.8 EON32322.1 - 0.018 14.8 0.1 0.059 13.1 0.1 2.0 1 1 0 1 1 1 0 DnaA N-terminal domain AAA_16 PF13191.6 EON32322.1 - 0.019 15.4 1.3 0.1 13.0 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain AFG1_ATPase PF03969.16 EON32322.1 - 0.033 13.1 0.1 1.1 8.1 0.0 2.4 1 1 1 2 2 2 0 AFG1-like ATPase FaeA PF04703.12 EON32322.1 - 0.056 13.8 0.2 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 FaeA-like protein AAA_24 PF13479.6 EON32322.1 - 0.17 11.6 0.0 0.54 10.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ribosomal_L34 PF00468.17 EON32323.1 - 1.1e-18 66.9 12.1 1.2e-18 66.7 12.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 Ribonuclease_P PF00825.18 EON32324.1 - 1.2e-21 76.8 0.0 1.6e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P YidD PF01809.18 EON32325.1 - 1.1e-25 89.3 0.1 1.4e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor 60KD_IMP PF02096.20 EON32326.1 - 7.3e-50 169.1 3.6 1e-49 168.7 3.6 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein R3H PF01424.22 EON32327.1 - 2.6e-14 52.9 0.0 4.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 R3H domain KH_4 PF13083.6 EON32327.1 - 4.2e-08 32.9 0.1 8.7e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 KH domain RXT2_N PF08595.11 EON32327.1 - 7.8 6.5 8.7 14 5.7 8.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal GidB PF02527.15 EON32328.1 - 1e-50 171.6 0.0 1.3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 EON32328.1 - 0.0035 16.9 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EON32328.1 - 0.0066 16.2 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EON32328.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase AAA_31 PF13614.6 EON32329.1 - 1.4e-56 191.2 0.0 1.8e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EON32329.1 - 5.7e-29 100.8 0.0 7e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EON32329.1 - 1.6e-10 40.9 1.2 2.5e-09 36.9 1.2 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EON32329.1 - 1.8e-10 40.7 0.1 3.5e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EON32329.1 - 3.8e-10 39.5 0.3 4.4e-08 32.7 0.3 2.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EON32329.1 - 3e-07 29.9 0.0 4.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EON32329.1 - 1.1e-05 25.1 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EON32329.1 - 0.0082 15.1 0.1 0.021 13.8 0.1 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EON32329.1 - 0.011 15.4 0.1 0.45 10.1 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EON32329.1 - 0.014 15.2 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein VirC1 PF07015.11 EON32329.1 - 0.017 14.5 0.2 0.046 13.0 0.1 1.7 1 1 1 2 2 2 0 VirC1 protein CLP1_P PF16575.5 EON32329.1 - 0.038 13.8 0.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 EON32329.1 - 0.059 12.9 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Methyltransf_24 PF13578.6 EON32329.1 - 0.12 13.4 0.0 0.57 11.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain ParBc PF02195.18 EON32330.1 - 6.3e-24 84.1 0.1 1.2e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 EON32330.1 - 4.1e-16 58.5 1.4 1.1e-15 57.2 0.4 2.2 2 0 0 2 2 2 1 HTH domain found in ParB protein TrmB PF01978.19 EON32330.1 - 0.0025 17.7 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EON32330.1 - 0.029 14.3 0.1 0.097 12.7 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain KorB PF08535.10 EON32330.1 - 0.03 14.4 0.0 0.17 12.0 0.0 2.0 1 1 1 2 2 2 0 KorB domain HTH_11 PF08279.12 EON32330.1 - 0.034 14.1 0.3 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 HTH domain HTH_38 PF13936.6 EON32330.1 - 0.09 12.6 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain SoPB_HTH PF18090.1 EON32330.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Centromere-binding protein HTH domain HTH_23 PF13384.6 EON32330.1 - 0.13 12.1 0.3 0.85 9.5 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Pkinase PF00069.25 EON32331.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain PG_binding_1 PF01471.18 EON32332.1 - 1.6e-26 92.3 0.0 2.5e-13 50.0 0.0 2.9 2 1 0 2 2 2 2 Putative peptidoglycan binding domain Amidase_3 PF01520.18 EON32332.1 - 2.1e-24 86.6 0.0 2.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_3 PF09374.10 EON32332.1 - 4.3e-07 30.1 0.0 0.65 10.3 0.0 3.7 2 1 0 2 2 2 2 Predicted Peptidoglycan domain PG_binding_2 PF08823.11 EON32332.1 - 0.022 15.1 0.0 0.92 9.9 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Thioredoxin PF00085.20 EON32333.1 - 3.8e-32 110.3 0.0 4.2e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EON32333.1 - 7.4e-09 35.8 0.0 7.4e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EON32333.1 - 4.8e-08 33.4 0.0 1.8e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EON32333.1 - 1.4e-05 25.0 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EON32333.1 - 5.3e-05 23.0 0.0 5.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EON32333.1 - 8.9e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EON32333.1 - 0.0001 22.0 0.1 0.00021 21.0 0.1 1.6 1 1 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 EON32333.1 - 0.00013 21.5 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EON32333.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein KaiB PF07689.12 EON32333.1 - 0.001 18.7 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 KaiB domain Thioredoxin_3 PF13192.6 EON32333.1 - 0.064 13.3 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.11 EON32333.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Pyr_redox_2 PF07992.14 EON32334.1 - 9.3e-47 159.7 2.6 1.1e-46 159.4 2.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON32334.1 - 6e-22 78.3 0.1 9.4e-17 61.2 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32334.1 - 2e-19 69.9 1.2 5.4e-18 65.3 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON32334.1 - 1.5e-07 30.9 9.7 0.00012 21.3 0.1 4.5 2 2 2 5 5 5 3 FAD binding domain HI0933_like PF03486.14 EON32334.1 - 4.4e-06 25.7 0.1 0.01 14.5 0.1 3.5 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 EON32334.1 - 6.4e-06 26.0 8.6 0.0075 15.9 0.1 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EON32334.1 - 1.2e-05 24.8 3.8 2.1e-05 24.1 0.5 2.7 2 2 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EON32334.1 - 2.5e-05 23.6 0.9 0.064 12.4 0.0 3.6 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EON32334.1 - 5.6e-05 23.3 0.1 0.0058 16.8 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON32334.1 - 0.0013 18.1 0.0 0.042 13.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EON32334.1 - 0.0042 16.2 6.0 0.038 13.1 0.3 3.5 3 1 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EON32334.1 - 0.013 15.9 0.5 0.07 13.6 0.2 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EON32334.1 - 0.18 10.6 1.8 1.4 7.7 0.0 2.6 3 1 0 3 3 3 0 Tryptophan halogenase RskA PF10099.9 EON32335.1 - 1.8 8.8 29.3 31 4.8 29.3 2.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Sigma70_r2 PF04542.14 EON32336.1 - 5.4e-15 54.9 2.1 9.9e-15 54.1 2.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON32336.1 - 1.2e-13 50.5 0.2 4.7e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON32336.1 - 2.2e-09 36.7 0.0 4.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON32336.1 - 4.6e-05 23.4 0.1 0.0002 21.3 0.1 1.9 1 1 0 1 1 1 1 ECF sigma factor HTH_17 PF12728.7 EON32336.1 - 0.0018 18.4 0.1 0.0047 17.1 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain DUF134 PF02001.16 EON32336.1 - 0.015 15.8 0.1 0.022 15.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF134 HTH_23 PF13384.6 EON32336.1 - 0.017 14.9 0.9 0.05 13.4 0.2 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 EON32336.1 - 0.15 12.2 1.6 0.17 12.0 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 EON32336.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Reoviridae_Vp9 PF08978.10 EON32336.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 NHase_beta PF02211.15 EON32337.1 - 0.003 17.6 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Nitrile hydratase beta subunit NHase_alpha PF02979.16 EON32338.1 - 6.2e-70 234.3 0.0 7.2e-70 234.0 0.0 1.0 1 0 0 1 1 1 1 Nitrile hydratase, alpha chain Frankia_peptide PF14407.6 EON32338.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. NHase_beta PF02211.15 EON32339.1 - 6e-55 186.6 0.4 7e-55 186.4 0.4 1.0 1 0 0 1 1 1 1 Nitrile hydratase beta subunit TetR_N PF00440.23 EON32340.1 - 2.3e-07 30.5 0.7 7.7e-07 28.8 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_AraC PF00165.23 EON32340.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family FA_hydroxylase PF04116.13 EON32341.1 - 6.5e-27 94.5 11.3 6.5e-27 94.5 11.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MurJ PF03023.14 EON32342.1 - 2.6e-92 309.8 24.8 3.7e-92 309.3 24.8 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ CarboxypepD_reg PF13620.6 EON32343.1 - 0.28 11.5 6.0 0.16 12.3 1.0 2.8 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain UL73_N PF12522.8 EON32343.1 - 2.1 8.2 7.5 13 5.7 7.5 2.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal NUDIX PF00293.28 EON32344.1 - 1.1e-21 77.2 0.2 1.9e-21 76.5 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EON32344.1 - 0.046 13.7 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain PolyA_pol PF01743.20 EON32345.1 - 5.7e-33 114.0 0.0 1.2e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EON32345.1 - 7.3e-17 60.9 0.0 1.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 EON32345.1 - 1.2e-13 51.4 0.2 2.4e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 HD domain tRNA_NucTran2_2 PF13735.6 EON32345.1 - 0.00026 21.0 0.0 0.00066 19.7 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DAGK_cat PF00781.24 EON32346.1 - 2.2e-22 79.0 1.5 3.8e-22 78.2 1.5 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EON32346.1 - 8.8e-05 21.8 1.7 0.00014 21.2 1.7 1.3 1 0 0 1 1 1 1 ATP-NAD kinase LSDAT_prok PF18171.1 EON32346.1 - 0.036 13.3 0.2 0.054 12.7 0.2 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote TetR_N PF00440.23 EON32347.1 - 6.9e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 EON32347.1 - 6.2e-05 22.7 0.0 0.00018 21.2 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON32347.1 - 0.00011 22.0 0.5 0.015 15.1 0.1 2.7 2 0 0 2 2 2 1 MarR family HTH_7 PF02796.15 EON32347.1 - 0.00012 22.1 0.0 0.00082 19.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON32347.1 - 0.00039 20.1 0.7 0.0017 18.1 0.2 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 EON32347.1 - 0.0015 18.3 0.2 0.0056 16.5 0.2 2.1 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EON32347.1 - 0.0018 17.6 0.1 0.0045 16.4 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 EON32347.1 - 0.0021 18.1 0.1 0.0063 16.6 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EON32347.1 - 0.0027 17.7 0.1 0.0072 16.3 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_22 PF13309.6 EON32347.1 - 0.0031 17.6 0.0 0.01 15.9 0.1 1.8 2 0 0 2 2 1 1 HTH domain SpoIIID PF12116.8 EON32347.1 - 0.0079 16.3 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_17 PF12728.7 EON32347.1 - 0.0097 16.1 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EON32347.1 - 0.011 15.2 0.1 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EON32347.1 - 0.012 15.4 0.0 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB LacI PF00356.21 EON32347.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family TetR_C_15 PF17918.1 EON32347.1 - 0.017 15.9 1.1 0.029 15.1 1.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_11 PF08279.12 EON32347.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_8 PF02954.19 EON32347.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sigma70_r4 PF04545.16 EON32347.1 - 0.069 12.7 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 EON32347.1 - 0.098 13.0 0.4 0.28 11.5 0.2 2.0 2 1 0 2 2 2 0 Transposase HTH_26 PF13443.6 EON32347.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DAO PF01266.24 EON32348.1 - 4e-45 154.9 7.1 5e-45 154.6 7.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EON32348.1 - 3.6e-14 52.7 0.0 7.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EON32348.1 - 1.3e-09 37.7 6.9 2.6e-08 33.4 7.0 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EON32348.1 - 0.00015 21.2 1.1 0.00015 21.2 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON32348.1 - 0.00052 19.3 0.5 0.002 17.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EON32348.1 - 0.00062 18.9 1.0 0.2 10.7 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 EON32348.1 - 0.0059 15.9 2.5 0.56 9.4 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EON32348.1 - 0.0069 15.5 0.4 0.0099 15.0 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EON32348.1 - 0.016 15.7 0.2 0.034 14.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON32348.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON32348.1 - 0.037 12.7 0.8 0.053 12.2 0.8 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 EON32348.1 - 0.043 13.7 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EON32348.1 - 0.057 13.7 3.7 0.23 11.7 1.5 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON32348.1 - 0.099 11.9 0.3 0.2 10.8 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Aminotran_5 PF00266.19 EON32349.1 - 9.6e-26 90.6 0.0 5.5e-24 84.8 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 EON32349.1 - 2.6e-08 33.5 0.0 7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EON32349.1 - 0.00045 18.8 0.0 0.00062 18.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 EON32349.1 - 0.0082 14.8 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase GDC-P PF02347.16 EON32349.1 - 0.094 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein VCBS PF13517.6 EON32350.1 - 5.3e-06 26.9 23.6 0.0084 16.7 0.5 3.5 3 1 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MFS_1 PF07690.16 EON32351.1 - 3.5e-09 36.1 29.5 3.5e-09 36.1 29.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1056 PF06341.11 EON32351.1 - 0.032 14.5 0.7 0.23 11.8 0.7 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) DUF179 PF02622.15 EON32352.1 - 4.9e-34 117.6 0.0 6.3e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Peptidase_S15 PF02129.18 EON32353.1 - 4.1e-55 187.3 0.0 6.8e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EON32353.1 - 3.9e-35 121.8 0.0 5.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 EON32353.1 - 0.00045 19.8 0.1 0.0011 18.6 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EON32353.1 - 0.019 14.3 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SfLAP PF11139.8 EON32355.1 - 3.3e-14 52.8 23.6 4.6e-14 52.4 23.6 1.3 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein TraL PF07178.11 EON32355.1 - 3.2 8.3 7.5 34 5.0 0.1 3.2 2 1 0 2 2 2 0 TraL protein TetR_N PF00440.23 EON32356.1 - 3.1e-08 33.3 0.4 8.9e-08 31.8 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 EON32356.1 - 0.0012 18.6 2.4 0.0039 17.0 0.2 2.7 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain TetR_C_24 PF17932.1 EON32356.1 - 0.0019 18.4 0.1 0.0058 16.9 0.0 1.9 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 EON32356.1 - 0.0023 18.2 1.3 0.0023 18.2 1.3 2.7 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_21 PF17926.1 EON32356.1 - 0.0039 17.3 0.9 0.0061 16.7 0.2 1.8 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 EON32356.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_20 PF12840.7 EON32356.1 - 0.013 15.5 0.6 0.057 13.5 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain MCD_N PF17408.2 EON32356.1 - 0.042 14.0 0.3 0.5 10.5 0.1 2.3 1 1 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain HTH_24 PF13412.6 EON32356.1 - 0.046 13.3 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding LacI PF00356.21 EON32356.1 - 0.069 12.9 0.7 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_AraC PF00165.23 EON32356.1 - 0.071 13.2 0.0 8 6.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_6 PF01418.17 EON32356.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 EON32356.1 - 0.14 12.0 2.8 0.21 11.4 1.1 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain Guanylate_cyc PF00211.20 EON32357.1 - 2.8e-09 36.9 0.0 1.5e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Caa3_CtaG PF09678.10 EON32358.1 - 7.5e-52 176.1 20.6 1.2e-51 175.5 20.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Frag1 PF10277.9 EON32358.1 - 0.31 10.5 8.1 14 5.1 8.1 2.3 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF2070 PF09843.9 EON32358.1 - 1.6 6.9 3.7 2.5 6.3 3.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2243 PF10002.9 EON32359.1 - 9.2e-53 178.1 17.3 1.1e-52 177.9 17.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DUF998 PF06197.13 EON32359.1 - 0.00015 21.5 9.6 0.0071 16.0 2.5 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF998) Tad PF13400.6 EON32359.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.9 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like DUF3040 PF11239.8 EON32359.1 - 0.65 10.3 6.7 20 5.5 0.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) SBF_like PF13593.6 EON32360.1 - 1.6e-93 313.5 23.9 1.8e-93 313.3 23.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EON32360.1 - 3.5e-11 43.2 8.9 3.5e-11 43.2 8.9 2.6 1 1 1 2 2 2 1 Sodium Bile acid symporter family SdpI PF13630.6 EON32361.1 - 2.9e-13 49.7 1.1 2.9e-13 49.7 1.1 2.2 2 0 0 2 2 2 1 SdpI/YhfL protein family Phage_holin_3_6 PF07332.11 EON32361.1 - 2.8 8.0 23.4 0.59 10.2 1.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III tRNA-synt_1_2 PF13603.6 EON32362.1 - 2.3e-61 206.5 0.0 4.5e-61 205.6 0.0 1.5 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 EON32362.1 - 1.6e-38 132.4 0.0 3e-18 65.4 0.0 4.9 3 2 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EON32362.1 - 5.4e-17 61.6 0.0 1.5e-13 50.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EON32362.1 - 3.5e-12 46.5 0.0 7.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EON32362.1 - 0.013 14.8 0.0 0.56 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain CPSase_L_D2 PF02786.17 EON32364.1 - 6.9e-79 264.2 0.2 1.2e-78 263.4 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EON32364.1 - 9.4e-44 148.5 0.5 2.8e-43 146.9 0.1 2.0 3 0 0 3 3 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EON32364.1 - 4.6e-37 126.4 0.0 1.2e-36 125.0 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EON32364.1 - 8.9e-18 63.9 4.1 2.4e-17 62.5 4.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EON32364.1 - 9.7e-10 38.1 3.2 3.3e-06 26.8 0.5 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EON32364.1 - 8.5e-09 35.2 0.9 2e-08 34.0 0.1 1.9 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EON32364.1 - 3.4e-06 26.7 0.0 9.1e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 EON32364.1 - 0.0002 22.0 3.1 0.4 11.4 0.4 3.3 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EON32364.1 - 0.0016 17.7 2.5 0.57 9.4 0.4 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EON32364.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 EON32364.1 - 0.11 12.6 5.5 0.23 11.6 0.1 3.6 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 GCV_H PF01597.19 EON32364.1 - 0.26 11.2 1.1 0.54 10.1 1.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 EON32364.1 - 3.4 7.9 7.9 5.8 7.2 3.9 3.3 3 1 0 3 3 2 0 Peptidase family M23 Condensation PF00668.20 EON32365.1 - 3e-20 72.3 0.0 4.2e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain SufE PF02657.15 EON32366.1 - 8.4e-27 93.5 0.0 9.4e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain Rhodanese PF00581.20 EON32367.1 - 4.4e-32 110.8 0.0 1.9e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain AMP-binding PF00501.28 EON32367.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Zn_peptidase PF04228.13 EON32369.1 - 2.5e-06 27.2 0.5 0.00035 20.1 0.5 2.6 1 1 0 1 1 1 1 Putative neutral zinc metallopeptidase Reprolysin_5 PF13688.6 EON32369.1 - 0.0078 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Maf PF02545.14 EON32370.1 - 7.3e-43 146.3 0.0 8.3e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ACC_epsilon PF13822.6 EON32371.1 - 4.5e-14 52.9 0.1 5.2e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit Carboxyl_trans PF01039.22 EON32372.1 - 1.8e-202 673.4 0.3 2.1e-202 673.2 0.3 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EON32372.1 - 0.022 14.3 2.9 0.07 12.6 0.2 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) BPL_LplA_LipB PF03099.19 EON32373.1 - 9e-12 45.0 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EON32373.1 - 1.2e-06 28.3 1.1 1.2e-06 28.3 1.1 2.0 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain QueT PF06177.11 EON32374.1 - 3.5 8.0 11.5 30 5.0 11.5 1.9 1 1 0 1 1 1 0 QueT transporter DUF2530 PF10745.9 EON32374.1 - 3.7 7.9 10.2 9 6.6 5.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) bPH_2 PF03703.14 EON32375.1 - 1.2e-17 63.9 0.2 1.6e-17 63.4 0.2 1.2 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 EON32375.1 - 0.16 12.3 0.0 0.42 11.0 0.0 1.6 1 1 0 1 1 1 0 Bacterial PH domain TMEM151 PF14857.6 EON32375.1 - 0.2 10.6 0.1 0.34 9.8 0.0 1.4 1 1 1 2 2 2 0 TMEM151 family Hyd_WA PF06462.12 EON32375.1 - 0.42 10.7 2.0 1.3 9.1 2.0 2.0 1 1 0 1 1 1 0 Propeller Trans_reg_C PF00486.28 EON32376.1 - 1.1e-25 89.5 0.4 2e-25 88.6 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EON32376.1 - 2.7e-24 85.5 0.0 3.9e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EON32377.1 - 1.7e-11 44.6 0.0 2.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EON32377.1 - 0.00038 20.8 0.1 0.0017 18.7 0.1 2.2 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 EON32377.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DraK_HK_N PF18092.1 EON32377.1 - 0.003 18.0 0.1 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 DraK Histidine Kinase N-terminal domain HisKA PF00512.25 EON32377.1 - 0.019 15.0 0.7 0.09 12.8 0.9 2.1 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain FtsX PF02687.21 EON32377.1 - 0.022 15.2 0.4 4.1 7.9 0.0 2.3 2 0 0 2 2 2 0 FtsX-like permease family GtrA PF04138.14 EON32378.1 - 1.3e-18 67.3 8.5 1.9e-18 66.8 8.5 1.2 1 0 0 1 1 1 1 GtrA-like protein DUF2929 PF11151.8 EON32378.1 - 0.027 14.8 3.9 0.25 11.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2929) ATP-grasp PF02222.22 EON32379.1 - 1.6e-46 158.0 0.0 2.3e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EON32379.1 - 1e-14 54.0 0.1 1.8e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EON32379.1 - 0.0013 18.3 0.0 0.0061 16.1 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EON32379.1 - 0.003 17.1 0.0 0.032 13.8 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Nterm_IS4 PF13006.7 EON32379.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal AIRC PF00731.20 EON32380.1 - 1.3e-65 219.5 0.8 1.5e-65 219.3 0.8 1.0 1 0 0 1 1 1 1 AIR carboxylase DUF2334 PF10096.9 EON32380.1 - 0.27 10.8 0.0 0.37 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DLH PF01738.18 EON32381.1 - 4.8e-10 39.4 0.0 8.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family F420H2_quin_red PF04075.14 EON32382.1 - 1.2e-06 28.7 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase AMP-binding PF00501.28 EON32383.1 - 3.6e-06 25.8 0.0 0.00024 19.8 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme LytR_cpsA_psr PF03816.14 EON32384.1 - 7.4e-41 139.8 0.0 3e-40 137.9 0.0 2.0 2 0 0 2 2 2 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 EON32384.1 - 1.3e-14 54.9 3.0 3.6e-14 53.5 3.0 1.8 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator RmlD_sub_bind PF04321.17 EON32385.1 - 6.1e-92 307.8 0.0 7e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EON32385.1 - 7.2e-12 45.3 0.0 9.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EON32385.1 - 5.3e-05 22.5 0.0 8.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EON32385.1 - 0.0089 15.2 0.5 0.069 12.3 0.0 2.3 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Glycos_transf_2 PF00535.26 EON32386.1 - 1e-16 61.2 0.0 1.6e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32386.1 - 3.1e-14 53.4 0.0 9e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON32386.1 - 6e-07 29.6 0.1 8.7e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EON32386.1 - 2.5e-06 27.1 0.0 9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EON32386.1 - 0.0013 18.3 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 EON32386.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase NTP_transferase PF00483.23 EON32387.1 - 1.8e-44 152.2 0.0 2.4e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON32387.1 - 6.6e-13 49.3 0.0 8.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EON32387.1 - 1.4e-09 37.3 9.0 0.0012 18.5 0.5 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EON32387.1 - 0.0023 17.7 12.0 0.079 12.7 1.3 3.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EON32387.1 - 0.076 11.1 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Methyltransf_3 PF01596.17 EON32388.1 - 7.9e-17 61.1 0.0 9.4e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EON32388.1 - 4.4e-15 56.6 0.0 8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32388.1 - 2.1e-08 34.8 0.0 4.4e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON32388.1 - 1.9e-07 31.7 0.0 3.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32388.1 - 0.00025 20.9 0.0 0.00091 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32388.1 - 0.0088 16.8 0.0 0.017 15.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32388.1 - 0.018 14.9 0.0 0.05 13.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EON32388.1 - 0.025 14.1 0.0 0.054 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EON32388.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EON32388.1 - 0.18 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Sigma70_r2 PF04542.14 EON32389.1 - 4.2e-22 77.7 0.4 7.4e-22 76.9 0.4 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON32389.1 - 1.2e-16 60.1 0.1 2.9e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON32389.1 - 8.4e-12 44.4 0.0 1.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON32389.1 - 0.00026 20.9 0.0 0.00043 20.2 0.0 1.4 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EON32389.1 - 0.00079 19.1 0.2 0.0019 17.9 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 EON32389.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 EON32389.1 - 0.08 13.1 0.4 0.31 11.2 0.2 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain TnsD PF15978.5 EON32389.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D DUF134 PF02001.16 EON32389.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 zf-HC2 PF13490.6 EON32390.1 - 0.00011 22.3 1.8 0.00042 20.5 1.7 2.0 2 0 0 2 2 2 1 Putative zinc-finger Trypsin_2 PF13365.6 EON32391.1 - 8.8e-34 117.6 1.6 2.3e-33 116.2 1.6 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EON32391.1 - 8.9e-16 58.4 0.0 1.5e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EON32391.1 - 6.5e-14 52.0 0.0 1.8e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EON32391.1 - 4.6e-12 45.6 0.5 2.4e-11 43.3 0.0 2.6 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 EON32391.1 - 3.8e-09 36.8 0.1 8.2e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 EON32391.1 - 0.0019 17.0 1.5 0.094 11.4 0.9 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 EON32391.1 - 0.084 12.1 4.2 1.1 8.3 0.2 2.6 2 1 1 3 3 3 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.21 EON32391.1 - 0.15 11.9 0.2 0.29 10.9 0.2 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease MttA_Hcf106 PF02416.16 EON32392.1 - 0.029 13.7 2.0 0.047 13.0 2.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family ParA PF10609.9 EON32393.1 - 9e-86 287.3 0.0 1.1e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 EON32393.1 - 5.2e-19 68.2 3.2 5.8e-19 68.0 0.7 2.4 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 EON32393.1 - 3.5e-12 46.5 0.0 1.6e-11 44.4 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EON32393.1 - 1.3e-08 34.9 0.0 7.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EON32393.1 - 1.3e-07 31.2 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 EON32393.1 - 3e-05 23.6 0.0 0.001 18.6 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EON32393.1 - 0.00038 19.7 0.3 0.00071 18.9 0.1 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EON32393.1 - 0.0042 16.6 0.3 0.17 11.3 0.3 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EON32393.1 - 0.0042 16.9 0.4 1.8 8.4 0.2 2.2 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 EON32393.1 - 0.0097 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.6 EON32393.1 - 0.039 13.5 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EON32393.1 - 0.045 12.7 0.7 0.11 11.4 0.2 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 EON32393.1 - 0.081 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 VirC1 protein CLP1_P PF16575.5 EON32393.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HMA PF00403.26 EON32393.1 - 0.3 11.5 1.1 2.1 8.9 0.0 2.7 3 0 0 3 3 3 0 Heavy-metal-associated domain SLT_2 PF13406.6 EON32394.1 - 5.9e-07 29.0 2.2 2.8e-06 26.8 0.2 2.0 1 1 0 2 2 2 2 Transglycosylase SLT domain DUF1003 PF06210.11 EON32395.1 - 3.9e-37 126.5 0.2 5.6e-37 126.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) DUF3037 PF11236.8 EON32395.1 - 0.015 15.7 0.2 0.023 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) MgtE_N PF03448.17 EON32396.1 - 6.3e-25 87.7 8.9 1.1e-24 86.9 8.9 1.4 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 EON32396.1 - 3.9e-12 46.4 1.7 9.4e-05 22.8 0.0 3.2 4 0 0 4 4 4 2 CBS domain PRC PF05239.16 EON32396.1 - 4.1e-06 26.8 0.1 5.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 PRC-barrel domain FliG_M PF14841.6 EON32396.1 - 6.4e-05 23.1 1.3 1.3 9.3 0.0 3.5 1 1 2 3 3 3 2 FliG middle domain FliG_N PF14842.6 EON32396.1 - 0.003 18.1 0.1 0.34 11.5 0.0 2.7 1 1 1 2 2 2 2 FliG N-terminal domain hnRNP_Q_AcD PF18360.1 EON32396.1 - 0.097 12.6 0.7 19 5.3 0.0 2.6 2 1 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain SBP_bac_1 PF01547.25 EON32398.1 - 4.4e-20 72.9 2.1 1.1e-19 71.6 2.1 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EON32398.1 - 5.3e-12 46.1 0.4 8.1e-12 45.5 0.4 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 EON32399.1 - 6e-12 45.7 19.3 6e-12 45.7 19.3 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ParBc PF02195.18 EON32401.1 - 0.016 15.5 0.5 0.052 13.9 0.5 1.8 1 1 0 1 1 1 0 ParB-like nuclease domain Metallophos PF00149.28 EON32402.1 - 6.3e-09 36.6 0.0 1e-08 36.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON32402.1 - 0.00012 22.3 0.0 0.00065 19.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EON32402.1 - 0.076 12.3 0.0 0.29 10.4 0.0 1.9 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily SUFU PF05076.13 EON32403.1 - 1e-33 116.7 0.0 1.2e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) MTS PF05175.14 EON32404.1 - 8.7e-16 57.9 0.0 1.2e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EON32404.1 - 5.3e-13 49.5 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32404.1 - 1.7e-11 44.1 0.0 2.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON32404.1 - 1.9e-11 43.9 0.2 2.7e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EON32404.1 - 3.7e-08 33.2 0.0 6.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EON32404.1 - 1.8e-06 28.5 0.1 4.8e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32404.1 - 5.8e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EON32404.1 - 0.00066 19.5 0.0 0.00091 19.0 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EON32404.1 - 0.00072 19.3 2.5 0.0021 17.7 0.6 2.3 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 EON32404.1 - 0.0017 19.1 0.0 0.0043 17.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EON32404.1 - 0.003 17.5 0.1 0.006 16.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.20 EON32404.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EON32404.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EON32404.1 - 0.026 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LPD22 PF18834.1 EON32404.1 - 0.048 13.9 0.7 0.11 12.7 0.7 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 Methyltransf_15 PF09445.10 EON32404.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase N6_Mtase PF02384.16 EON32404.1 - 0.087 12.1 0.0 1.6 7.9 0.0 2.0 2 0 0 2 2 2 0 N-6 DNA Methylase DUF43 PF01861.16 EON32404.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain FtsJ PF01728.19 EON32404.1 - 0.21 11.7 0.0 0.32 11.1 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase zf-CDGSH PF09360.10 EON32405.1 - 4.1e-17 62.1 0.2 5.3e-17 61.8 0.2 1.2 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Haem_oxygenas_2 PF14518.6 EON32406.1 - 9.2e-39 133.1 0.4 1.2e-38 132.6 0.4 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme HhH-GPD PF00730.25 EON32407.1 - 0.00028 21.3 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Nup54_57_C PF18570.1 EON32407.1 - 0.045 13.3 0.2 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain DUF4332 PF14229.6 EON32407.1 - 0.14 12.4 0.2 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Tim29 PF10171.9 EON32407.1 - 0.18 11.3 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 CorA PF01544.18 EON32408.1 - 1.2e-57 195.5 0.0 1.4e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF371 PF04027.13 EON32408.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF371) OpuAC PF04069.12 EON32409.1 - 1.4e-12 47.8 0.0 4e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system adh_short PF00106.25 EON32410.1 - 4e-48 163.5 1.9 5.6e-48 163.0 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32410.1 - 1.4e-36 126.3 2.9 1.7e-36 125.9 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32410.1 - 1e-14 54.8 1.2 1.7e-14 54.2 0.3 1.7 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 EON32410.1 - 0.0035 17.3 0.8 0.0035 17.3 0.8 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain eIF-6 PF01912.18 EON32410.1 - 0.071 12.5 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 eIF-6 family FMO-like PF00743.19 EON32411.1 - 9.5e-21 73.8 0.0 6.3e-18 64.5 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON32411.1 - 4.6e-18 65.5 0.0 9.8e-17 61.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON32411.1 - 1.8e-15 56.9 0.4 5.7e-13 48.7 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EON32411.1 - 3.4e-11 43.2 2.2 4.9e-11 42.7 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON32411.1 - 2.9e-10 39.8 0.0 8.3e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON32411.1 - 1.7e-07 31.2 1.2 4.5e-05 23.2 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EON32411.1 - 0.00047 19.4 0.1 0.54 9.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON32411.1 - 0.00053 20.0 0.2 0.014 15.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON32411.1 - 0.0022 17.2 0.0 0.0057 15.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EON32411.1 - 0.004 16.4 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain eIF-1a PF01176.19 EON32411.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Thi4 PF01946.17 EON32411.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TetR_N PF00440.23 EON32412.1 - 4e-10 39.3 0.1 9e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON32412.1 - 0.032 14.4 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase DUF4383 PF14325.6 EON32413.1 - 1.2e-46 158.0 17.6 1.4e-46 157.8 17.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) NMN_transporter PF04973.12 EON32413.1 - 0.033 14.2 3.7 0.048 13.6 3.8 1.3 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter TssN PF17555.2 EON32413.1 - 0.19 11.0 2.1 0.24 10.7 2.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN TMEM107 PF14995.6 EON32413.1 - 0.46 10.9 6.0 0.22 12.0 2.2 2.0 1 1 1 2 2 2 0 Transmembrane protein DUF2754 PF10953.8 EON32413.1 - 2.3 8.5 0.0 2.3 8.5 0.0 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF2754) DUF872 PF05915.12 EON32413.1 - 8.4 6.6 6.7 1.7 8.8 0.1 2.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Condensation PF00668.20 EON32414.1 - 7.6e-14 51.2 0.0 1.3e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Condensation domain Condensation PF00668.20 EON32415.1 - 5.7e-12 45.1 0.0 1.2e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Condensation domain Condensation PF00668.20 EON32416.1 - 1.1e-17 63.9 0.0 1e-13 50.8 0.0 2.5 2 1 0 2 2 2 2 Condensation domain ABC_tran PF00005.27 EON32417.1 - 2.6e-27 96.0 0.0 3.9e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32417.1 - 7.4e-12 45.7 0.3 8.8e-09 35.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EON32417.1 - 4.5e-06 27.3 0.0 7.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SRP54 PF00448.22 EON32417.1 - 0.0023 17.6 0.2 0.0039 16.9 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EON32417.1 - 0.0043 17.3 0.1 0.029 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain KdpD PF02702.17 EON32417.1 - 0.0043 16.6 0.0 0.0091 15.5 0.0 1.5 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain SbcCD_C PF13558.6 EON32417.1 - 0.0076 16.5 0.0 0.029 14.6 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EON32417.1 - 0.0077 16.6 0.4 0.016 15.6 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON32417.1 - 0.013 15.2 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EON32417.1 - 0.014 15.7 0.2 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EON32417.1 - 0.023 15.2 0.0 0.03 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON32417.1 - 0.029 14.1 0.9 0.055 13.2 0.7 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EON32417.1 - 0.031 14.3 0.0 0.038 14.1 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MukB PF04310.12 EON32417.1 - 0.036 13.9 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA PF00004.29 EON32417.1 - 0.041 14.3 0.0 0.23 11.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EON32417.1 - 0.043 13.5 0.0 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 EON32417.1 - 0.14 11.3 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 EON32417.1 - 0.18 12.0 0.8 0.74 10.0 0.8 2.0 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EON32417.1 - 0.27 8.7 0.4 0.35 8.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC2_membrane PF01061.24 EON32418.1 - 1.4e-26 93.2 12.0 1.4e-26 93.2 12.0 1.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON32418.1 - 3.7e-11 42.7 10.5 3.7e-11 42.7 10.5 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein Glycos_transf_2 PF00535.26 EON32419.1 - 5.8e-32 110.8 0.1 9e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32419.1 - 3.2e-21 76.3 0.3 4.9e-21 75.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON32419.1 - 3.7e-09 36.5 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EON32419.1 - 3.8e-06 27.3 0.0 6.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EON32419.1 - 1e-05 25.6 1.1 1.8e-05 24.8 1.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EON32419.1 - 0.00011 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_28 PF03033.20 EON32420.1 - 4.1e-06 26.9 0.0 7.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EON32420.1 - 0.0003 19.7 0.0 0.00042 19.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase HEAT_2 PF13646.6 EON32420.1 - 1.5 9.3 6.0 1.5 9.3 0.2 3.1 4 1 1 5 5 5 0 HEAT repeats Glyco_transf_28 PF03033.20 EON32421.1 - 7.2e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain XdhC_C PF13478.6 EON32421.1 - 0.0061 17.1 0.2 3.9 8.0 0.0 2.6 2 0 0 2 2 2 2 XdhC Rossmann domain Glyco_tran_28_C PF04101.16 EON32421.1 - 0.15 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 EON32421.1 - 0.6 10.1 6.6 0.33 10.9 2.1 2.7 2 2 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 EON32424.1 - 5.3e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EON32424.1 - 0.059 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase E1_dh PF00676.20 EON32425.1 - 4.2e-58 196.7 0.0 8.6e-58 195.6 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component Transket_pyr PF02779.24 EON32425.1 - 6.2e-55 185.6 0.0 1.1e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain 2-oxoacid_dh PF00198.23 EON32425.1 - 2.8e-54 184.0 0.1 4.3e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) OxoGdeHyase_C PF16870.5 EON32425.1 - 8.1e-44 149.0 0.0 1.4e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EON32425.1 - 3.3e-08 33.0 0.6 6.2e-08 32.1 0.6 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus ABC_membrane PF00664.23 EON32426.1 - 2.6e-65 220.8 21.5 8.7e-33 114.1 8.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EON32426.1 - 6.2e-60 201.7 0.0 1.5e-30 106.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EON32426.1 - 6.7e-09 35.5 0.0 0.18 11.2 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON32426.1 - 1.2e-08 35.5 4.4 0.00017 22.0 0.7 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EON32426.1 - 1.3e-07 31.2 0.1 0.01 15.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EON32426.1 - 1.8e-07 31.5 0.1 0.064 13.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EON32426.1 - 2.6e-06 27.5 0.1 0.19 11.7 0.0 3.7 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EON32426.1 - 1.9e-05 24.3 6.6 0.19 11.3 0.1 4.4 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 EON32426.1 - 6.9e-05 22.2 0.1 0.19 11.0 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.23 EON32426.1 - 0.00013 22.0 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EON32426.1 - 0.00013 22.5 0.1 0.069 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EON32426.1 - 0.00018 21.3 4.2 0.51 10.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EON32426.1 - 0.00048 20.6 0.2 1.4 9.3 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EON32426.1 - 0.00067 19.8 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EON32426.1 - 0.00073 20.1 0.1 1.2 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EON32426.1 - 0.00096 18.9 0.2 1.1 9.0 0.0 3.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 EON32426.1 - 0.00097 19.3 0.1 0.54 10.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EON32426.1 - 0.0014 18.5 0.2 3.6 7.3 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EON32426.1 - 0.0015 18.5 0.0 0.69 9.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 EON32426.1 - 0.0016 18.6 1.2 0.62 10.3 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EON32426.1 - 0.0042 16.6 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 EON32426.1 - 0.0092 15.2 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EON32426.1 - 0.0096 15.7 0.1 1.8 8.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EON32426.1 - 0.012 15.4 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 EON32426.1 - 0.014 14.8 0.0 12 5.3 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 EON32426.1 - 0.017 15.5 0.0 8.4 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 EON32426.1 - 0.03 14.3 0.4 10 6.0 0.0 3.2 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 EON32426.1 - 0.036 14.0 0.0 5.5 6.9 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 EON32426.1 - 0.059 13.6 2.1 2.9 8.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.7 EON32426.1 - 0.071 12.0 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.6 EON32426.1 - 0.074 13.5 0.7 2.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 EON32426.1 - 0.093 12.1 0.0 6 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 EON32426.1 - 0.11 12.2 0.1 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 EON32426.1 - 0.79 9.4 4.9 3.3 7.4 0.1 3.1 3 0 0 3 3 3 0 Cytidylate kinase HTH_32 PF13565.6 EON32427.1 - 0.13 12.9 0.0 0.27 11.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Phage_portal PF04860.12 EON32427.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein GST_C_2 PF13410.6 EON32428.1 - 5.6e-13 48.7 0.1 3.2e-12 46.3 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EON32428.1 - 4.1e-12 46.2 0.1 1.6e-11 44.3 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EON32428.1 - 1.6e-05 25.1 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EON32428.1 - 0.00038 20.6 0.0 0.00071 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EON32428.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EON32428.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain INT_SG_DDX_CT_C PF15300.6 EON32428.1 - 0.21 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus MFS_1 PF07690.16 EON32429.1 - 3.9e-57 193.8 47.0 3.9e-57 193.8 47.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32429.1 - 3e-07 29.7 12.4 3e-07 29.7 12.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EON32429.1 - 7.5e-05 21.8 21.6 0.0047 15.8 5.2 3.0 2 1 0 2 2 2 2 MFS_1 like family PUCC PF03209.15 EON32429.1 - 0.0031 16.6 11.3 0.0031 16.6 11.3 3.9 2 1 2 4 4 4 1 PUCC protein DUF4536 PF15055.6 EON32429.1 - 0.0056 16.9 0.1 0.075 13.3 0.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4536) MFS_3 PF05977.13 EON32429.1 - 0.037 12.4 29.0 0.0081 14.6 13.0 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 EON32429.1 - 1.8 6.7 11.8 0.2 9.9 0.1 3.6 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Metallophos PF00149.28 EON32430.1 - 4.4e-13 50.2 0.0 8.5e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON32430.1 - 1.4e-08 35.1 0.7 1.2e-07 32.0 0.5 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SbcD_C PF12320.8 EON32430.1 - 4.2e-05 23.8 0.0 0.00012 22.3 0.0 1.8 2 0 0 2 2 2 1 Type 5 capsule protein repressor C-terminal domain Methyltransf_2 PF00891.18 EON32430.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain AAA_23 PF13476.6 EON32431.1 - 1.1e-20 75.0 0.0 6.7e-20 72.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EON32431.1 - 1.3e-12 47.8 0.1 4.2e-12 46.1 0.1 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 EON32431.1 - 2.3e-07 30.6 0.0 2.3e-07 30.6 0.0 3.1 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.6 EON32431.1 - 1.7e-05 24.4 0.0 3.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON32431.1 - 0.00058 19.4 0.0 0.019 14.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON32431.1 - 0.069 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 EON32431.1 - 0.13 12.6 0.2 0.13 12.6 0.2 3.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF108 PF01958.18 EON32431.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF108 DUF1664 PF07889.12 EON32431.1 - 0.18 11.9 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_21 PF13304.6 EON32431.1 - 0.21 11.3 0.0 0.7 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MIS13 PF08202.11 EON32431.1 - 0.23 10.7 0.3 3.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Mis12-Mtw1 protein family Spc7 PF08317.11 EON32431.1 - 1.4 7.8 10.1 0.043 12.7 0.4 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein Atg14 PF10186.9 EON32431.1 - 4.6 6.2 5.6 0.55 9.3 0.6 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Flagellar_rod PF05149.12 EON32431.1 - 9.5 5.6 8.0 19 4.6 0.0 3.4 3 0 0 3 3 3 0 Paraflagellar rod protein HNH PF01844.23 EON32432.1 - 2.1e-14 53.4 0.1 2.8e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON32432.1 - 6.1e-10 38.8 0.0 9.5e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EON32432.1 - 6.3e-05 22.8 0.0 9.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 HNH endonuclease Endonuclease_7 PF02945.15 EON32432.1 - 0.025 14.5 0.1 0.056 13.4 0.0 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII Anti-TRAP PF15777.5 EON32432.1 - 0.91 9.5 3.1 0.7 9.9 0.3 2.3 2 2 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein MspA PF09203.11 EON32433.1 - 9.9e-35 120.0 1.8 1.2e-34 119.7 1.8 1.0 1 0 0 1 1 1 1 MspA PA PF02225.22 EON32434.1 - 1.2e-07 31.7 0.1 3.9e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 PA domain RHS PF03527.14 EON32434.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 RHS protein Abhydrolase_3 PF07859.13 EON32435.1 - 2.9e-58 197.2 0.0 3.6e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EON32435.1 - 1.6e-07 30.6 0.1 5.4e-07 28.8 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EON32435.1 - 5.3e-06 26.1 0.2 2.3e-05 24.0 0.1 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EON32435.1 - 0.00073 18.3 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EON32435.1 - 0.0027 18.3 10.8 0.0053 17.4 10.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EON32435.1 - 0.018 15.0 0.0 0.098 12.6 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 EON32435.1 - 0.047 13.4 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 EON32435.1 - 0.088 12.3 0.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_25 PF13649.6 EON32436.1 - 1e-15 58.2 0.1 1.2e-15 58.0 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32436.1 - 2.8e-15 56.4 0.0 3.4e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON32436.1 - 2.1e-11 44.3 0.0 2.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32436.1 - 1e-08 35.8 0.0 1.4e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EON32436.1 - 7.2e-08 32.4 0.0 7.8e-08 32.3 0.0 1.2 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EON32436.1 - 1.5e-06 28.2 0.0 6.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EON32436.1 - 1.5e-05 24.5 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EON32436.1 - 0.00028 20.5 0.0 0.0065 16.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EON32436.1 - 0.00073 19.1 0.0 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase GCD14 PF08704.10 EON32436.1 - 0.0011 18.7 0.0 0.0031 17.2 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 EON32436.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.17 EON32436.1 - 0.0044 16.2 0.0 0.011 14.9 0.0 1.5 2 0 0 2 2 2 1 Fibrillarin RrnaAD PF00398.20 EON32436.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 EON32436.1 - 0.029 14.0 0.0 0.047 13.3 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.19 EON32436.1 - 0.06 13.4 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF305 PF03713.13 EON32437.1 - 2.3e-41 141.5 16.7 1.8e-40 138.5 16.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 EON32437.1 - 4e-05 23.9 0.4 0.33 11.2 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4142) DUF3105 PF11303.8 EON32438.1 - 1e-42 145.3 0.0 1.6e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) Imm52 PF15579.6 EON32438.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 52 DALR_1 PF05746.15 EON32439.1 - 8.6e-37 126.0 0.0 1.4e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 EON32439.1 - 1.6e-19 70.0 0.0 4.6e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 EON32439.1 - 1.9e-19 70.0 0.0 6e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 EON32439.1 - 1.7e-07 30.3 1.3 0.13 11.0 0.0 3.5 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EON32439.1 - 0.00013 20.3 0.1 0.00031 19.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EON32439.1 - 0.028 13.3 0.0 0.95 8.3 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (K) HIRAN PF08797.11 EON32439.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain Orn_Arg_deC_N PF02784.16 EON32440.1 - 2.1e-62 210.7 0.1 3.4e-62 210.0 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EON32440.1 - 1.7e-14 53.8 0.1 2.5e-14 53.3 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 EON32440.1 - 0.00018 21.3 0.1 0.00029 20.6 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Homoserine_dh PF00742.19 EON32441.1 - 4.4e-65 218.8 0.4 7.5e-65 218.1 0.4 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EON32441.1 - 1e-20 74.6 0.2 2.9e-20 73.1 0.2 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 EON32441.1 - 1.2e-09 37.8 0.0 3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain Sacchrp_dh_NADP PF03435.18 EON32441.1 - 4.6e-05 23.7 3.0 0.0002 21.6 0.2 2.9 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EON32441.1 - 0.017 15.5 0.1 0.13 12.7 0.0 2.4 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NapD PF03927.13 EON32441.1 - 0.09 12.8 0.1 0.44 10.6 0.1 2.2 1 0 0 1 1 1 0 NapD protein NlpE_C PF17185.4 EON32441.1 - 0.18 12.1 0.0 0.49 10.7 0.0 1.8 1 0 0 1 1 1 0 NlpE C-terminal OB domain PALP PF00291.25 EON32442.1 - 2.1e-72 244.0 8.0 2.4e-72 243.8 8.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_N PF00288.26 EON32443.1 - 1.6e-08 34.7 3.4 1.6e-08 34.7 3.4 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EON32443.1 - 6.5e-05 23.2 0.0 0.00022 21.6 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Rho_RNA_bind PF07497.12 EON32444.1 - 9.7e-28 95.9 0.7 3.4e-27 94.1 0.2 2.1 2 0 0 2 2 2 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 EON32444.1 - 1.8e-23 83.3 0.0 2.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 EON32444.1 - 2.8e-13 49.5 0.0 3.2e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain AAA_25 PF13481.6 EON32444.1 - 5.1e-05 22.9 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EON32444.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HemS PF05171.12 EON32445.1 - 7.3e-09 35.7 0.0 0.003 17.5 0.0 2.1 2 0 0 2 2 2 2 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 EON32445.1 - 1.8e-08 34.2 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 2 Haem utilisation ChuX/HutX FAD_binding_1 PF00667.20 EON32446.1 - 1.5e-31 109.7 0.0 5.5e-31 107.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EON32446.1 - 1.3e-17 64.4 0.0 2.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ribosomal_L31 PF01197.18 EON32447.1 - 2.9e-33 113.9 0.2 3.2e-33 113.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 PCRF PF03462.18 EON32448.1 - 1.7e-64 217.3 0.1 1e-63 214.7 0.0 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EON32448.1 - 7.5e-40 135.5 2.2 1.3e-39 134.7 2.2 1.4 1 0 0 1 1 1 1 RF-1 domain ABC_tran_CTD PF16326.5 EON32448.1 - 0.011 16.0 7.4 0.14 12.4 0.1 3.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain PrmC_N PF17827.1 EON32449.1 - 9.5e-21 74.2 0.1 4.4e-20 72.1 0.2 2.0 2 0 0 2 2 2 1 PrmC N-terminal domain MTS PF05175.14 EON32449.1 - 4.2e-09 36.2 0.0 8.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EON32449.1 - 8.8e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EON32449.1 - 0.00065 20.4 0.2 0.0036 18.0 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.17 EON32449.1 - 0.0059 16.1 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_19 PF04672.12 EON32449.1 - 0.012 15.1 0.6 0.021 14.3 0.6 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase Met_10 PF02475.16 EON32449.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EON32449.1 - 0.019 14.4 0.4 0.031 13.7 0.2 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Sua5_yciO_yrdC PF01300.18 EON32450.1 - 3.3e-44 150.5 0.0 3.9e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination DUF5632 PF18646.1 EON32450.1 - 0.041 13.9 0.2 0.18 11.9 0.1 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5632) HTH_20 PF12840.7 EON32450.1 - 0.11 12.6 0.3 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain SHMT PF00464.19 EON32451.1 - 4.5e-117 391.0 0.0 5.8e-117 390.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EON32451.1 - 6.2e-06 25.6 0.0 1.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EON32451.1 - 1e-05 25.0 0.7 5.2e-05 22.7 0.7 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EON32451.1 - 0.0009 18.3 0.0 0.0016 17.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EON32451.1 - 0.009 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EON32451.1 - 0.032 12.7 0.0 0.066 11.7 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SelA PF03841.13 EON32451.1 - 0.084 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Glycos_transf_4 PF00953.21 EON32452.1 - 1.5e-34 119.3 15.5 1.5e-34 119.3 15.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 4 ATP-synt_I PF03899.15 EON32453.1 - 0.0015 18.8 11.4 0.0018 18.6 10.0 1.7 1 1 1 2 2 2 1 ATP synthase I chain ATP-synt_A PF00119.20 EON32454.1 - 5.7e-49 166.9 17.7 7.2e-49 166.6 17.7 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_C PF00137.21 EON32455.1 - 1.1e-07 32.1 10.6 1.7e-07 31.5 10.6 1.4 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_B PF00430.18 EON32456.1 - 4.3e-20 72.1 10.9 5e-20 71.9 10.9 1.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) tRNA_anti-like PF12869.7 EON32456.1 - 0.012 15.3 0.6 0.017 14.7 0.6 1.2 1 0 0 1 1 1 0 tRNA_anti-like Mt_ATP-synt_B PF05405.14 EON32456.1 - 0.077 12.6 0.9 0.28 10.8 0.9 1.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) YMF19 PF02326.15 EON32456.1 - 0.1 13.4 0.0 0.2 12.4 0.0 1.6 1 1 0 1 1 1 0 Plant ATP synthase F0 NfeD PF01957.18 EON32456.1 - 0.16 12.3 0.4 1.4 9.4 0.1 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding SAPS PF04499.15 EON32456.1 - 0.4 9.4 3.2 0.5 9.1 3.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF883 PF05957.13 EON32456.1 - 0.5 11.0 11.1 1 10.0 10.6 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FeoB_associated PF12669.7 EON32456.1 - 7.5 7.1 4.8 11 6.5 4.8 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein OSCP PF00213.18 EON32457.1 - 1e-29 103.9 8.5 3.7e-29 102.1 0.2 3.2 3 1 0 3 3 3 1 ATP synthase delta (OSCP) subunit ATP-synt_B PF00430.18 EON32457.1 - 3.1e-22 79.1 11.7 3.1e-22 79.1 11.7 2.0 3 0 0 3 3 3 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EON32457.1 - 0.00023 21.5 15.9 0.00084 19.7 15.9 2.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Mt_ATP-synt_B PF05405.14 EON32457.1 - 0.00095 18.8 1.1 0.0017 18.0 1.1 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2570 PF10828.8 EON32457.1 - 0.019 14.8 1.4 0.044 13.6 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Phage_GPO PF05929.11 EON32457.1 - 3 7.4 10.5 1.5 8.4 6.7 2.3 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIVA PF05103.13 EON32457.1 - 4.7 7.3 14.7 10 6.2 14.7 1.6 1 1 0 1 1 1 0 DivIVA protein ATP-synt_ab PF00006.25 EON32458.1 - 2.1e-66 223.7 0.0 2.9e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EON32458.1 - 2.9e-42 144.0 0.0 5.4e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EON32458.1 - 2.1e-13 50.6 0.3 5.2e-13 49.3 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain EutQ PF06249.12 EON32458.1 - 0.11 12.2 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ ATP-synt PF00231.19 EON32459.1 - 1.3e-89 300.6 0.0 1.5e-89 300.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase WASH-7_N PF14745.6 EON32459.1 - 0.17 10.3 0.1 0.24 9.8 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal ATP-synt_ab PF00006.25 EON32460.1 - 1.3e-61 208.0 0.0 2.3e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EON32460.1 - 3e-22 78.9 0.1 8.9e-22 77.4 0.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EON32460.1 - 0.0019 18.6 0.1 0.048 14.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 EON32460.1 - 0.0022 17.8 0.7 0.0098 15.7 0.7 2.1 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 EON32460.1 - 0.0035 16.7 0.3 0.008 15.5 0.3 1.7 1 0 0 1 1 1 1 KaiC RsgA_GTPase PF03193.16 EON32460.1 - 0.0062 16.5 1.0 0.013 15.4 0.2 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EON32460.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EON32460.1 - 0.061 13.6 2.5 0.27 11.6 0.5 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EON32460.1 - 0.074 13.4 0.9 0.57 10.5 0.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EON32460.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EON32460.1 - 0.086 13.2 0.0 0.5 10.8 0.0 2.2 3 0 0 3 3 2 0 RNA helicase DUF2806 PF10987.8 EON32460.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) NB-ARC PF00931.22 EON32460.1 - 0.16 11.1 1.0 0.36 10.0 0.2 1.8 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_DE_N PF02823.16 EON32461.1 - 1.6e-24 85.6 0.9 2e-24 85.3 0.9 1.1 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2550 PF10739.9 EON32462.1 - 1.7e-41 141.2 0.1 2e-41 141.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2550) MHYT PF03707.16 EON32462.1 - 0.56 10.4 4.9 1.1 9.5 4.9 1.5 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF3377 PF11857.8 EON32462.1 - 3.4 7.7 5.6 6 6.9 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cob_adeno_trans PF01923.18 EON32463.1 - 1e-55 188.4 0.0 1.2e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase EPSP_synthase PF00275.20 EON32464.1 - 1.4e-101 340.3 0.4 1.6e-101 340.1 0.4 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Fe-ADH PF00465.19 EON32465.1 - 2e-111 372.3 0.1 2.5e-111 372.0 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EON32465.1 - 9.9e-09 35.3 1.7 0.00042 20.1 0.1 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AAA_5 PF07728.14 EON32466.1 - 4.2e-14 52.7 0.1 2.4e-13 50.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EON32466.1 - 3.7e-11 43.6 0.0 1.6e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EON32466.1 - 8.4e-09 35.4 0.1 0.00026 20.8 0.1 2.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EON32466.1 - 1e-08 35.8 1.1 2.2e-08 34.7 1.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 EON32466.1 - 0.00021 21.0 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EON32466.1 - 0.00022 21.5 0.1 0.0013 19.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_6 PF12774.7 EON32466.1 - 0.00029 19.9 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 EON32466.1 - 0.00048 19.9 0.7 0.0019 17.9 0.7 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON32466.1 - 0.00098 18.9 0.1 0.45 10.2 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EON32466.1 - 0.0018 18.9 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EON32466.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EON32466.1 - 0.0067 16.4 0.5 0.041 13.8 0.5 2.1 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 EON32466.1 - 0.0086 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EON32466.1 - 0.016 15.0 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EON32466.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON32466.1 - 0.063 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EON32466.1 - 0.067 13.5 0.9 0.45 10.8 0.9 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EON32466.1 - 0.077 13.4 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EON32466.1 - 0.098 12.7 0.0 3.4 7.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EON32466.1 - 0.1 12.0 0.2 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EON32466.1 - 0.16 12.1 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.23 EON32466.1 - 0.17 11.0 0.1 0.82 8.7 0.0 2.0 3 0 0 3 3 3 0 MCM P-loop domain VWA_CoxE PF05762.14 EON32467.1 - 6e-28 97.7 3.4 1.1e-27 96.8 3.4 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Fe-ADH PF00465.19 EON32468.1 - 6e-111 370.8 3.9 6.8e-111 370.6 3.9 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EON32468.1 - 2.4e-16 60.2 0.1 6e-08 32.7 0.4 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HisKA_3 PF07730.13 EON32469.1 - 6.8e-13 48.9 0.4 6.8e-13 48.9 0.4 3.8 4 0 0 4 4 4 1 Histidine kinase HATPase_c_2 PF13581.6 EON32469.1 - 1.2e-05 25.2 0.1 3.9e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 EON32469.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 EON32469.1 - 0.0044 17.3 1.6 0.0044 17.3 1.6 2.3 2 1 1 3 3 3 1 GAF domain DUF3384 PF11864.8 EON32469.1 - 0.09 11.7 0.2 0.85 8.4 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3384) GAF PF01590.26 EON32469.1 - 0.096 13.3 0.3 0.27 11.8 0.3 1.8 1 0 0 1 1 1 0 GAF domain Response_reg PF00072.24 EON32470.1 - 5.5e-24 84.5 0.2 8.1e-24 84.0 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON32470.1 - 2.3e-21 75.1 0.1 4e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON32470.1 - 3.5e-07 29.8 0.7 1.3e-06 28.0 0.1 2.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON32470.1 - 3.2e-06 26.6 0.3 9.7e-06 25.0 0.3 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EON32470.1 - 0.00025 20.7 0.6 0.013 15.3 0.0 2.7 2 1 1 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 EON32470.1 - 0.00084 18.8 0.1 0.0023 17.4 0.1 1.9 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding TadZ_N PF16968.5 EON32470.1 - 0.0019 17.9 1.6 0.0021 17.7 0.8 1.6 2 0 0 2 2 2 1 Pilus assembly protein TadZ N-terminal HTH_10 PF04967.12 EON32470.1 - 0.0027 17.4 0.2 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 HTH DNA binding domain HTH_38 PF13936.6 EON32470.1 - 0.0067 16.2 0.5 0.023 14.4 0.2 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 EON32470.1 - 0.025 14.6 0.5 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 EON32470.1 - 0.053 13.5 0.5 0.13 12.3 0.5 1.7 1 0 0 1 1 1 0 HTH domain Methyltransf_11 PF08241.12 EON32471.1 - 3.1e-12 47.0 0.1 5.3e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32471.1 - 2.3e-11 44.2 0.0 3.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32471.1 - 0.0011 19.7 0.0 0.0017 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32471.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON32471.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SBF PF01758.16 EON32472.1 - 7.7e-09 35.5 0.4 1.2e-08 34.9 0.0 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family Kinocilin PF15033.6 EON32472.1 - 0.0062 16.2 0.3 0.008 15.8 0.3 1.2 1 0 0 1 1 1 1 Kinocilin protein HTH_5 PF01022.20 EON32473.1 - 9.7e-16 57.4 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON32473.1 - 3.1e-15 56.0 0.1 7.9e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EON32473.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EON32473.1 - 0.0024 18.2 0.0 0.0039 17.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 EON32473.1 - 0.0027 17.3 0.0 0.041 13.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EON32473.1 - 0.021 14.7 0.0 0.069 13.1 0.0 1.8 1 1 1 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 EON32473.1 - 0.054 13.5 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 EON32473.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_42 PF06224.12 EON32474.1 - 1.1e-53 183.0 15.7 1.1e-53 183.0 15.7 1.3 1 1 0 1 1 1 1 Winged helix DNA-binding domain WD40 PF00400.32 EON32475.1 - 9.3e-50 165.6 13.7 2.6e-07 31.2 0.0 11.2 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EON32475.1 - 5.2e-15 55.5 0.0 0.91 9.9 0.0 8.9 4 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EON32475.1 - 1.2e-08 34.7 2.4 1.3 9.1 0.0 5.0 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EON32475.1 - 3.3e-08 32.9 0.6 0.18 10.7 0.1 5.7 3 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EON32475.1 - 0.00012 22.5 2.6 0.00028 21.3 1.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EON32475.1 - 0.047 13.4 0.0 0.26 11.0 0.0 2.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EON32475.1 - 0.29 11.4 1.4 2 8.7 0.1 2.4 1 1 0 2 2 2 0 AAA domain COesterase PF00135.28 EON32476.1 - 2e-104 350.3 0.0 3.5e-104 349.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON32476.1 - 6.1e-14 52.4 3.1 4.7e-13 49.5 3.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_trans_4_4 PF13579.6 EON32476.1 - 0.0051 17.3 2.3 0.0051 17.3 2.3 3.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Peptidase_S9 PF00326.21 EON32476.1 - 0.012 15.1 0.3 0.018 14.5 0.3 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family YdjM PF04307.14 EON32477.1 - 0.018 14.3 3.6 0.038 13.3 3.6 1.5 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Cpta_toxin PF07254.12 EON32477.1 - 0.069 13.1 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system DUF5353 PF17304.2 EON32477.1 - 0.25 11.1 1.6 1.9 8.3 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5353) SUR7 PF06687.12 EON32477.1 - 0.38 10.3 1.8 0.46 10.1 1.8 1.5 1 1 0 1 1 1 0 SUR7/PalI family Claudin_2 PF13903.6 EON32477.1 - 0.64 9.7 5.6 0.43 10.3 0.8 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.6 EON32477.1 - 3.3 7.3 9.9 0.29 10.8 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribonuc_L-PSP PF01042.21 EON32478.1 - 3.7e-20 72.1 0.3 4.4e-20 71.9 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_6 PF12697.7 EON32479.1 - 1.9e-16 61.4 11.6 2.4e-16 61.0 11.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON32479.1 - 1.9e-08 34.3 0.2 1.1e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON32479.1 - 1.8e-07 30.7 0.2 1.8e-06 27.4 0.2 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 EON32479.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ThrE PF06738.12 EON32480.1 - 4.4e-66 222.7 35.0 6.2e-59 199.3 10.3 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EON32480.1 - 5.3e-17 62.2 11.6 5.3e-17 62.2 11.6 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF2866 PF11065.8 EON32481.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Glyco_transf_20 PF00982.21 EON32482.1 - 2.6e-148 494.6 0.0 3e-148 494.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EON32482.1 - 0.01 15.4 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 GTP-bdg_M PF16360.5 EON32482.1 - 0.082 13.5 0.4 0.38 11.4 0.1 2.1 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Trehalose_PPase PF02358.16 EON32483.1 - 5.5e-34 117.3 0.0 6.8e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Aldedh PF00171.22 EON32483.1 - 0.009 14.6 0.8 1.2 7.6 0.2 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Peptidase_Mx PF15887.5 EON32484.1 - 7.6e-83 277.5 0.0 9.5e-83 277.2 0.0 1.0 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase Peptidase_Mx1 PF15890.5 EON32484.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase Transglut_core PF01841.19 EON32485.1 - 2.5e-20 73.0 0.0 3.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 EON32485.1 - 9.4e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like domain ROK PF00480.20 EON32486.1 - 3.4e-12 46.4 0.1 4.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 ROK family MarR_2 PF12802.7 EON32486.1 - 4e-10 39.4 1.3 1.7e-08 34.3 0.3 3.1 3 0 0 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 EON32486.1 - 1.2e-06 28.4 0.0 4.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DprA_WH PF17782.1 EON32486.1 - 7.6e-05 22.8 1.2 0.00032 20.7 1.2 2.1 1 0 0 1 1 1 1 DprA winged helix domain HTH_29 PF13551.6 EON32486.1 - 0.00022 21.1 0.0 0.0028 17.6 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_24 PF13412.6 EON32486.1 - 0.00052 19.5 0.1 0.0069 15.9 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EON32486.1 - 0.00057 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EON32486.1 - 0.00064 19.7 0.1 0.00064 19.7 0.1 3.8 5 1 1 6 6 5 1 Helix-turn-helix domain Crp PF00325.20 EON32486.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_IclR PF09339.10 EON32486.1 - 0.019 14.7 0.3 0.019 14.7 0.3 2.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_11 PF08279.12 EON32486.1 - 0.02 14.8 0.1 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 HTH domain DUF2243 PF10002.9 EON32486.1 - 0.033 14.3 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) HTH_15 PF12324.8 EON32486.1 - 0.07 13.1 1.3 0.2 11.7 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Fe_dep_repress PF01325.19 EON32486.1 - 0.073 13.3 0.0 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain RP-C PF03428.13 EON32486.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Replication protein C N-terminal domain Rrf2 PF02082.20 EON32486.1 - 0.11 12.8 0.0 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator HTH_27 PF13463.6 EON32486.1 - 0.11 12.9 0.0 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_AsnC-type PF13404.6 EON32486.1 - 0.12 12.3 2.0 0.82 9.6 0.1 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain adh_short PF00106.25 EON32487.1 - 3.9e-41 140.7 0.1 4.9e-41 140.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32487.1 - 3.9e-31 108.4 0.1 5e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON32487.1 - 5.4e-08 32.9 4.0 6.2e-08 32.7 4.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON32487.1 - 2.5e-07 30.4 0.2 3.9e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON32487.1 - 2.4e-05 24.3 0.9 3.7e-05 23.7 0.9 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EON32487.1 - 0.076 12.1 0.4 0.15 11.2 0.4 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Big_10 PF17964.1 EON32488.1 - 5.5e-59 199.2 0.4 7.6e-59 198.7 0.4 1.2 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 EON32488.1 - 3.3e-10 40.6 0.0 6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain TAT_signal PF10518.9 EON32488.1 - 0.0059 16.4 6.2 0.012 15.4 6.2 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 EON32488.1 - 0.64 9.4 4.2 1.2 8.5 4.2 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal HTH_3 PF01381.22 EON32489.1 - 1.9e-12 47.0 0.0 2.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON32489.1 - 4.3e-12 46.2 3.2 9.2e-12 45.1 3.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 EON32489.1 - 6.8e-10 38.5 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 EON32489.1 - 5.2e-08 33.2 0.0 7.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 EON32489.1 - 5.3e-07 29.6 0.0 7.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 EON32489.1 - 0.00046 20.1 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_25 PF13413.6 EON32489.1 - 0.00055 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EON32489.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON32489.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_38 PF13936.6 EON32489.1 - 0.014 15.2 0.3 0.039 13.7 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_25 PF13649.6 EON32490.1 - 2.4e-18 66.6 0.0 5.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON32490.1 - 3.7e-18 66.0 0.0 7.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32490.1 - 3.6e-16 59.3 0.0 5.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32490.1 - 5e-15 56.0 0.0 1.3e-14 54.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32490.1 - 1.2e-14 54.5 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON32490.1 - 4.7e-07 29.5 0.0 8.7e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EON32490.1 - 8.1e-07 28.5 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EON32490.1 - 6.4e-06 25.7 0.0 9.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EON32490.1 - 0.00034 21.6 3.7 0.00054 21.0 0.1 2.6 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_PK PF05891.12 EON32490.1 - 0.0032 17.0 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 EON32490.1 - 0.0047 16.7 0.0 0.0066 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EON32490.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.10 EON32490.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DREV PF05219.12 EON32490.1 - 0.023 13.8 0.0 0.05 12.7 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Rsm22 PF09243.10 EON32490.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 EON32490.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EON32490.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Pyr_redox_2 PF07992.14 EON32491.1 - 1.5e-21 76.9 3.6 2e-21 76.5 3.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON32491.1 - 2.3e-06 26.6 0.3 0.00012 21.0 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EON32491.1 - 2.7e-06 26.8 0.3 0.015 14.5 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON32491.1 - 1.8e-05 24.5 15.9 0.00022 20.9 3.5 3.2 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EON32491.1 - 1.9e-05 24.7 8.4 0.56 10.2 0.1 3.4 3 0 0 3 3 3 3 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON32491.1 - 0.00011 21.5 9.1 0.00011 21.5 9.1 2.8 1 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EON32491.1 - 0.00011 22.3 0.3 0.00011 22.3 0.3 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON32491.1 - 0.00017 20.9 0.8 0.00055 19.2 0.2 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EON32491.1 - 0.00034 20.0 0.4 0.00061 19.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EON32491.1 - 0.00055 20.4 0.5 0.067 13.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON32491.1 - 0.0012 18.0 4.1 0.025 13.7 1.2 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EON32491.1 - 0.0015 17.4 7.9 0.053 12.4 0.5 2.5 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EON32491.1 - 0.0035 16.5 7.0 0.0053 15.9 1.1 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein TrkA_N PF02254.18 EON32491.1 - 0.018 15.3 1.4 0.22 11.8 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EON32491.1 - 0.062 12.4 0.1 3 6.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EON32491.1 - 0.15 11.4 7.8 0.029 13.7 3.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EON32491.1 - 0.35 11.3 3.3 2 8.9 0.1 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 EON32491.1 - 3.9 6.7 9.8 0.62 9.3 1.5 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EON32491.1 - 5.3 6.3 10.4 0.047 13.0 1.4 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DeoC PF01791.9 EON32492.1 - 6.8e-14 52.0 4.6 8.8e-14 51.7 4.6 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EON32492.1 - 0.0016 17.7 2.4 0.0051 16.1 0.9 2.0 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase Formyl_trans_N PF00551.19 EON32493.1 - 5.9e-37 127.1 0.0 9.3e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EON32493.1 - 0.00019 21.2 0.0 0.00062 19.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain Acetyltransf_9 PF13527.7 EON32494.1 - 0.0061 16.6 0.0 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1952 PF09189.10 EON32494.1 - 0.053 13.4 0.5 4 7.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1952) Acetyltransf_1 PF00583.25 EON32494.1 - 0.099 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CN_hydrolase PF00795.22 EON32496.1 - 4e-35 121.4 0.0 4.6e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2505 PF10698.9 EON32498.1 - 1.1e-43 149.1 0.0 1.2e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) DUF2505 PF10698.9 EON32499.1 - 2.5e-37 128.4 0.4 3e-37 128.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) FeS_assembly_P PF01883.19 EON32499.1 - 0.03 14.5 0.1 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein MurB_C PF02873.16 EON32500.1 - 1.1e-37 128.8 0.0 1.8e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 EON32500.1 - 1.1e-18 67.3 2.8 1.1e-18 67.3 2.8 1.9 3 0 0 3 3 3 1 FAD binding domain Abhydrolase_1 PF00561.20 EON32501.1 - 1.6e-26 93.5 0.0 3.6e-24 85.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON32501.1 - 3.8e-23 82.0 0.1 6e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON32501.1 - 1.4e-21 78.2 4.5 1.4e-21 78.2 4.5 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EON32501.1 - 1.1e-07 31.5 0.0 0.0018 17.8 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 EON32501.1 - 1.1e-06 28.7 0.3 0.00026 20.9 0.3 2.4 2 1 0 2 2 2 1 Serine hydrolase Esterase PF00756.20 EON32501.1 - 1.8e-06 27.8 0.0 4e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 EON32501.1 - 0.0006 19.4 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EON32501.1 - 0.0025 16.8 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EON32501.1 - 0.0033 17.3 0.8 0.14 12.0 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EON32501.1 - 0.0039 17.3 0.2 0.15 12.1 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_5 PF12695.7 EON32501.1 - 0.0056 16.5 0.0 0.05 13.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON32501.1 - 0.0069 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 EON32501.1 - 0.017 14.9 0.0 4.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EON32501.1 - 0.032 13.9 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein GutM PF06923.11 EON32501.1 - 0.067 13.3 0.0 1 9.4 0.0 2.3 1 1 0 1 1 1 0 Glucitol operon activator protein (GutM) DUF915 PF06028.11 EON32501.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Form-deh_trans PF09163.11 EON32501.1 - 0.63 9.9 4.0 3.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane MerR_1 PF13411.6 EON32502.1 - 1.4e-18 66.7 0.1 4.2e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 EON32502.1 - 1.7e-08 34.0 0.0 5.2e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 MerR family regulatory protein DUF2516 PF10724.9 EON32503.1 - 7.6e-28 96.6 5.6 8.8e-28 96.4 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2516) DUF3488 PF11992.8 EON32503.1 - 0.15 11.0 3.7 0.097 11.6 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) HRG PF16954.5 EON32503.1 - 0.17 12.3 0.7 0.17 12.3 0.7 2.8 1 1 2 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene PhoR PF11808.8 EON32503.1 - 7.7 7.0 8.1 0.83 10.1 2.1 2.0 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR PRA1 PF03208.19 EON32503.1 - 9.7 5.8 10.0 27 4.4 10.1 1.6 1 1 0 1 1 1 0 PRA1 family protein Pentapeptide PF00805.22 EON32504.1 - 0.0031 17.1 0.2 0.0031 17.1 0.2 3.0 2 1 1 3 3 3 1 Pentapeptide repeats (8 copies) HTH_3 PF01381.22 EON32505.1 - 1.6e-14 53.6 0.3 2.5e-14 53.1 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON32505.1 - 2.3e-12 47.1 1.5 2.6e-12 46.9 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 EON32505.1 - 1.1e-07 31.7 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 EON32505.1 - 0.0082 15.9 0.2 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Rrf2 PF02082.20 EON32505.1 - 0.0087 16.4 0.0 0.034 14.5 0.0 2.0 1 1 2 3 3 3 1 Transcriptional regulator HTH_25 PF13413.6 EON32505.1 - 0.0088 15.9 0.1 0.039 13.8 0.0 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 EON32505.1 - 0.13 12.2 0.2 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF445 PF04286.12 EON32506.1 - 8.4e-97 325.2 0.0 9.8e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Inhibitor_G39P PF11417.8 EON32506.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P RuvA_C PF07499.13 EON32506.1 - 0.019 15.4 2.7 0.048 14.1 2.7 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain DnaG_DnaB_bind PF08278.11 EON32506.1 - 0.3 11.7 3.6 7.9 7.1 0.0 3.3 3 1 0 3 3 3 0 DNA primase DnaG DnaB-binding TetR_N PF00440.23 EON32507.1 - 1.2e-07 31.4 0.1 1.2e-07 31.4 0.1 2.8 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family Adeno_E1B_19K PF01691.16 EON32507.1 - 0.019 14.5 0.4 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen HTH_Tnp_1_2 PF13022.6 EON32507.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 EON32507.1 - 0.19 11.9 0.2 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 EON32507.1 - 0.2 11.7 0.0 0.56 10.3 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix adh_short PF00106.25 EON32508.1 - 5.7e-29 101.0 0.0 1.3e-28 99.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32508.1 - 1e-25 90.7 0.0 1.6e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EON32508.1 - 0.0047 16.4 0.1 0.0078 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON32508.1 - 0.16 11.8 3.6 0.91 9.4 1.9 2.4 2 1 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 EON32508.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PPK2 PF03976.14 EON32509.1 - 1e-62 211.7 0.0 1.3e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) BenE PF03594.13 EON32510.1 - 8.6e-96 321.0 46.7 1.1e-95 320.7 46.7 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein HTH_3 PF01381.22 EON32511.1 - 3.9e-13 49.2 0.1 5.4e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EON32511.1 - 3.9e-11 42.8 0.0 5.5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EON32511.1 - 1e-09 38.6 1.6 1.9e-09 37.7 0.8 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Cupin_2 PF07883.11 EON32511.1 - 3.6e-05 23.4 0.8 5.5e-05 22.8 0.8 1.3 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 EON32511.1 - 7.8e-05 23.0 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EON32511.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EON32511.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_N PF00440.23 EON32511.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Phage_CI_repr PF07022.13 EON32511.1 - 0.087 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_35 PF13693.6 EON32511.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FCD PF07729.12 EON32512.1 - 0.0097 16.3 3.8 0.015 15.7 2.6 1.9 1 1 1 2 2 2 1 FCD domain TPR_14 PF13428.6 EON32512.1 - 0.082 13.8 2.4 0.27 12.2 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apolipoprotein PF01442.18 EON32513.1 - 0.00018 21.4 14.6 0.0095 15.8 14.3 2.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EON32513.1 - 0.011 16.4 14.9 0.26 11.9 2.6 3.7 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 EON32513.1 - 0.03 14.4 0.5 2.2 8.3 0.0 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus VirE_N PF08800.10 EON32513.1 - 0.032 14.3 0.0 0.094 12.8 0.0 1.7 1 1 1 2 2 2 0 VirE N-terminal domain DUF2884 PF11101.8 EON32513.1 - 0.051 13.1 1.6 3 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) DUF1045 PF06299.12 EON32513.1 - 0.066 13.2 3.7 0.42 10.6 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1045) DUF5339 PF17274.2 EON32513.1 - 0.091 13.6 0.5 0.33 11.8 0.4 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5339) YtxH PF12732.7 EON32513.1 - 0.2 12.2 18.9 0.49 11.0 0.3 4.2 2 1 0 2 2 2 0 YtxH-like protein DPM3 PF08285.11 EON32513.1 - 0.2 11.8 0.2 0.5 10.6 0.0 1.7 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Syntaxin-6_N PF09177.11 EON32513.1 - 0.43 11.2 2.8 3.3 8.3 0.2 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EON32513.1 - 1.5 7.6 5.1 0.63 8.9 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.9 EON32513.1 - 1.6 9.4 4.9 17 6.1 0.3 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TPR_MLP1_2 PF07926.12 EON32513.1 - 7.5 6.6 7.8 2 8.5 1.6 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1690 PF07956.11 EON32513.1 - 9.3 6.7 9.7 1.1 9.6 2.4 2.3 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) 3HCDH_N PF02737.18 EON32514.1 - 7.4e-55 185.6 0.2 1.9e-54 184.3 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EON32514.1 - 3.1e-31 107.8 0.0 7.3e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EON32514.1 - 0.00078 19.6 0.9 0.0017 18.5 0.5 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EON32514.1 - 0.0094 15.3 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EON32514.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EON32514.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EON32514.1 - 0.042 14.1 0.2 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EON32514.1 - 0.065 13.3 0.7 1 9.4 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EON32514.1 - 0.11 12.7 1.1 0.35 11.0 1.1 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_8 PF13450.6 EON32514.1 - 0.12 12.6 0.3 0.28 11.4 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain KCNQ_channel PF03520.14 EON32514.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel ICL PF00463.21 EON32515.1 - 4.1e-98 329.2 2.0 9.8e-53 179.4 0.1 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 EON32515.1 - 2.8e-16 59.7 0.1 5.5e-16 58.7 0.1 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase BDV_P10 PF06515.11 EON32516.1 - 0.031 14.3 1.0 0.25 11.4 0.0 2.6 2 0 0 2 2 2 0 Borna disease virus P10 protein DUF2083 PF09856.9 EON32517.1 - 3.1e-68 228.6 0.0 4.6e-68 228.0 0.0 1.3 1 0 0 1 1 1 1 Predicted transcriptional regulator (DUF2083) Peptidase_M78 PF06114.13 EON32517.1 - 2.3e-21 76.0 0.1 5e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 IrrE N-terminal-like domain HTH_31 PF13560.6 EON32517.1 - 2.8e-12 46.8 0.2 8e-12 45.3 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EON32517.1 - 3.7e-12 46.1 0.0 1.1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EON32517.1 - 1.8e-10 40.7 0.0 4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 EON32517.1 - 1.9e-05 24.5 0.3 6e-05 22.8 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EON32517.1 - 0.00038 20.8 0.0 0.00092 19.6 0.0 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 EON32517.1 - 0.046 13.2 0.3 0.16 11.6 0.3 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 EON32517.1 - 0.18 11.4 0.2 0.42 10.2 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 EON32517.1 - 0.2 11.6 0.4 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LIP PF03583.14 EON32518.1 - 1.5e-37 129.5 0.0 2e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase LIP PF03583.14 EON32519.1 - 1.5e-40 139.3 0.0 2.8e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase Cutinase PF01083.22 EON32519.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase MaoC_dehydratas PF01575.19 EON32520.1 - 4.4e-27 94.1 0.0 5.5e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON32520.1 - 2.2e-09 37.6 0.0 2.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase CMD PF02627.20 EON32521.1 - 4.9e-12 45.7 0.0 1.1e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Methyltransf_25 PF13649.6 EON32522.1 - 1e-21 77.5 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON32522.1 - 2.7e-21 76.0 0.0 4.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32522.1 - 2.4e-20 72.9 0.0 2.9e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON32522.1 - 3e-16 59.5 0.0 5.4e-16 58.6 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EON32522.1 - 1.8e-11 44.6 0.0 2.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32522.1 - 1.8e-10 40.9 0.0 3e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EON32522.1 - 0.00011 21.3 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 EON32522.1 - 0.00044 19.9 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 EON32522.1 - 0.046 13.8 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EON32522.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox_2 PF07992.14 EON32524.1 - 3.9e-64 216.7 5.3 4.7e-64 216.4 5.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EON32524.1 - 2.1e-34 118.1 0.0 6e-34 116.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EON32524.1 - 7.8e-24 84.0 1.0 4.5e-21 75.2 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON32524.1 - 9.4e-10 38.2 7.9 3.4e-08 33.1 1.7 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON32524.1 - 7.1e-08 32.1 5.7 0.0012 18.1 0.3 3.2 2 1 1 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EON32524.1 - 4.8e-07 29.9 2.8 0.0049 17.1 0.3 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EON32524.1 - 5.5e-07 29.0 5.6 4.2e-05 22.8 0.5 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 EON32524.1 - 5.7e-07 28.6 7.0 0.0044 15.8 0.2 3.2 2 1 1 3 3 3 3 HI0933-like protein FAD_binding_2 PF00890.24 EON32524.1 - 7.5e-06 25.3 10.8 0.0011 18.2 0.6 4.2 4 0 0 4 4 4 2 FAD binding domain FAD_oxidored PF12831.7 EON32524.1 - 2.5e-05 23.8 0.2 2.5e-05 23.8 0.2 2.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 EON32524.1 - 0.00024 20.4 1.7 0.14 11.4 0.1 2.7 3 0 0 3 3 3 2 Thi4 family 3HCDH_N PF02737.18 EON32524.1 - 0.00026 20.9 0.6 0.00061 19.7 0.1 1.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EON32524.1 - 0.0057 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 EON32524.1 - 0.013 15.1 10.9 0.43 10.1 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON32524.1 - 0.018 14.3 0.3 0.073 12.3 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 EON32524.1 - 0.043 12.9 0.2 0.81 8.8 0.1 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 EON32524.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EON32524.1 - 0.28 10.5 3.7 5.9 6.1 0.1 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TetR_N PF00440.23 EON32525.1 - 5.5e-13 48.5 0.6 8.6e-13 47.9 0.2 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_30 PF17939.1 EON32525.1 - 9.8e-05 22.6 3.3 0.00019 21.7 1.1 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Oxidored_FMN PF00724.20 EON32526.1 - 2.6e-48 165.0 0.0 6.5e-43 147.3 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 EON32526.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 EON32526.1 - 0.016 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Dus PF01207.17 EON32526.1 - 0.049 12.7 0.0 0.48 9.5 0.0 2.1 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) Beta-lactamase PF00144.24 EON32527.1 - 3.6e-57 194.1 1.8 4.5e-57 193.8 1.8 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EON32527.1 - 7.5e-12 45.6 0.0 2.4e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Peptidase_S9 PF00326.21 EON32528.1 - 3e-52 177.2 0.1 4.9e-52 176.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EON32528.1 - 5.1e-32 111.2 0.2 4.5e-25 88.3 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 EON32528.1 - 0.0019 17.5 0.4 1.8 7.8 0.3 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EON32528.1 - 0.0088 15.6 0.1 0.035 13.6 0.1 1.9 2 0 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 EON32528.1 - 0.043 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 EON32528.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein GrpE PF01025.19 EON32529.1 - 1e-08 35.0 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 GrpE HSP70 PF00012.20 EON32530.1 - 2.3e-85 287.0 0.0 1.3e-66 225.1 0.0 3.0 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 EON32530.1 - 5.5e-08 32.0 0.0 1.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 EON32530.1 - 3.4e-05 23.7 0.1 6.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain NolV PF06635.12 EON32531.1 - 0.014 14.8 1.2 0.014 14.8 1.2 2.0 2 0 0 2 2 2 0 Nodulation protein NolV TetR_C_24 PF17932.1 EON32531.1 - 0.98 9.7 5.2 0.41 10.9 1.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TerD PF02342.18 EON32532.1 - 4.8e-05 22.9 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 TerD domain Cyclase PF04199.13 EON32533.1 - 3.1e-32 111.7 0.1 3.7e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase TPP_enzyme_N PF02776.18 EON32534.1 - 2e-40 138.2 3.4 2e-40 138.2 3.4 3.4 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON32534.1 - 1.6e-24 86.4 2.0 1.9e-23 82.9 0.0 3.0 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON32534.1 - 4.4e-21 75.0 0.7 8.9e-21 74.1 0.7 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Trp_oprn_chp PF09534.10 EON32535.1 - 0.022 14.6 22.0 0.11 12.3 15.6 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ResB PF05140.14 EON32535.1 - 0.1 11.3 0.3 0.14 10.9 0.3 1.1 1 0 0 1 1 1 0 ResB-like family HEPN_SAV_6107 PF18726.1 EON32535.1 - 6.8 7.3 9.4 0.18 12.3 2.4 1.9 2 1 0 2 2 2 0 SAV_6107-like HEPN PPK2 PF03976.14 EON32536.1 - 1.1e-102 342.4 1.6 1.3e-102 342.2 1.6 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) Polyketide_cyc2 PF10604.9 EON32538.1 - 4.6e-10 39.9 0.3 5.5e-10 39.7 0.3 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON32538.1 - 5.5e-10 39.6 0.0 8.9e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4166 PF13761.6 EON32539.1 - 1.2e-35 123.0 0.0 1.3e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4166) TetR_N PF00440.23 EON32540.1 - 2.1e-08 33.8 0.0 4.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 EON32540.1 - 0.093 12.7 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 4HBT PF03061.22 EON32541.1 - 3.7e-15 56.0 2.2 4.9e-15 55.7 2.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EON32541.1 - 6.7e-07 29.5 0.0 8.9e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EON32541.1 - 0.018 15.3 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Glyco_hydro_3 PF00933.21 EON32542.1 - 5.9e-52 177.0 0.0 1e-51 176.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EON32542.1 - 1.1e-51 175.8 0.0 1.9e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EON32542.1 - 1.6e-26 92.2 0.5 3.2e-26 91.2 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 EON32542.1 - 0.1 12.9 2.7 0.47 10.8 1.0 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF11 Y_phosphatase3 PF13350.6 EON32543.1 - 2.2e-63 214.3 0.0 2.5e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EON32543.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EON32543.1 - 0.057 13.0 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Esterase PF00756.20 EON32544.1 - 2.9e-37 128.7 0.0 3.7e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF222 PF02720.17 EON32546.1 - 2.5e-33 115.9 18.1 2.7e-32 112.5 17.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON32546.1 - 0.019 15.2 0.6 0.045 13.9 0.2 1.9 2 0 0 2 2 2 0 HNH endonuclease Cpn60_TCP1 PF00118.24 EON32547.1 - 2e-92 310.4 12.6 2.7e-92 309.9 12.6 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bac_luciferase PF00296.20 EON32548.1 - 5.3e-36 124.6 12.1 1.2e-34 120.2 12.1 2.2 1 1 0 1 1 1 1 Luciferase-like monooxygenase DUF4178 PF13785.6 EON32549.1 - 7.9e-31 107.1 2.2 9.8e-31 106.8 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4178) BT1 PF03092.16 EON32549.1 - 0.093 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 BT1 family DUF4330 PF14221.6 EON32549.1 - 0.17 12.1 0.0 7.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) DUF2617 PF10936.8 EON32550.1 - 9.4e-51 172.1 0.5 1.1e-50 171.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF2617 DUF4247 PF14042.6 EON32551.1 - 1.2e-24 87.3 0.1 1.5e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4247) DUF350 PF03994.14 EON32552.1 - 1.2e-31 108.6 11.6 2.7e-16 59.4 2.4 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) p53-inducible11 PF14936.6 EON32552.1 - 0.0072 16.4 0.7 0.0097 16.0 0.7 1.1 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF5336 PF17270.2 EON32552.1 - 0.23 11.1 4.5 0.34 10.5 4.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF4491 PF14898.6 EON32552.1 - 0.32 11.5 6.2 7.1 7.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Spermine_synth PF01564.17 EON32553.1 - 7.9e-28 97.1 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 EON32553.1 - 5.8e-05 23.7 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON32553.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EON32553.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EON32553.1 - 0.028 15.1 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EON32553.1 - 0.05 14.6 0.1 0.25 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EON32553.1 - 0.078 13.7 0.0 0.22 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PHBC_N PF12551.8 EON32553.1 - 0.33 10.8 2.7 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal DUF1422 PF07226.11 EON32553.1 - 3.5 7.7 9.3 6.3 6.9 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) NADH-u_ox-rdase PF10785.9 EON32553.1 - 8.4 7.2 7.7 1.6 9.4 0.2 3.2 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit adh_short PF00106.25 EON32554.1 - 3e-12 46.4 0.1 9e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EON32554.1 - 0.002 17.7 0.1 0.77 9.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TetR_N PF00440.23 EON32555.1 - 1.3e-13 50.5 0.1 3.6e-13 49.1 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 EON32555.1 - 7.4e-11 42.7 5.5 7.4e-11 42.7 5.5 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain AbiEi_4 PF13338.6 EON32555.1 - 0.091 12.9 0.2 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Phage_AlpA PF05930.12 EON32555.1 - 0.11 12.3 0.0 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) His_kinase PF06580.13 EON32556.1 - 7.4e-23 80.7 0.0 1.4e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 EON32556.1 - 4.6e-08 33.5 0.0 8.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EON32556.1 - 0.00087 19.2 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EON32556.1 - 0.0052 16.6 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 EON32556.1 - 0.011 16.1 0.2 0.023 15.1 0.2 1.6 1 0 0 1 1 1 0 GAF domain Response_reg PF00072.24 EON32557.1 - 5.2e-25 87.8 0.0 7.9e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain LytTR PF04397.15 EON32557.1 - 4.3e-19 68.5 0.0 7.1e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 LytTr DNA-binding domain Nucleos_tra2_C PF07662.13 EON32558.1 - 0.044 13.6 0.0 0.052 13.4 0.0 1.0 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus DUF2374 PF09574.10 EON32558.1 - 0.094 12.5 0.3 0.094 12.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) DUF485 PF04341.12 EON32558.1 - 0.16 11.9 1.4 0.22 11.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 SSF PF00474.17 EON32559.1 - 3.7e-41 141.3 32.6 5.1e-25 88.2 10.1 2.4 2 1 0 2 2 2 2 Sodium:solute symporter family MotA_ExbB PF01618.16 EON32559.1 - 3.2 7.5 8.2 6.5 6.5 2.8 2.6 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF485 PF04341.12 EON32560.1 - 7e-37 125.3 1.4 8e-37 125.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 DUF4191 PF13829.6 EON32560.1 - 0.15 11.4 0.4 0.17 11.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SSF PF00474.17 EON32561.1 - 6.4e-96 321.7 39.6 9.5e-96 321.1 39.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 EON32561.1 - 0.017 15.7 0.2 0.017 15.7 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2818) Amidase PF01425.21 EON32562.1 - 3.5e-80 270.2 0.0 5.1e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Amidase VbhA PF18495.1 EON32562.1 - 5.6 6.9 6.4 2.8 7.9 0.5 3.1 3 0 0 3 3 3 0 Antitoxin VbhA TetR_C_11 PF16859.5 EON32563.1 - 4.8e-19 68.7 5.1 7.4e-19 68.1 4.6 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32563.1 - 7.7e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_17 PF12728.7 EON32563.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EON32563.1 - 0.055 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_28 PF13518.6 EON32563.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain BChl_A PF02327.17 EON32563.1 - 0.095 11.5 0.0 0.21 10.4 0.0 1.5 1 1 0 1 1 1 0 Bacteriochlorophyll A protein HTH_38 PF13936.6 EON32563.1 - 0.1 12.3 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 EON32564.1 - 7e-24 84.4 59.7 2.3e-19 69.6 43.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32564.1 - 6.3e-08 31.9 12.3 6.3e-08 31.9 12.3 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EON32564.1 - 5.2e-07 28.9 0.0 0.089 11.6 9.7 2.2 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 EON32564.1 - 0.00036 19.1 13.0 0.00036 19.1 13.0 2.6 1 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) TetR_C_24 PF17932.1 EON32565.1 - 5e-32 110.6 0.9 6e-32 110.3 0.3 1.4 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32565.1 - 6.5e-17 61.1 0.6 1.2e-16 60.3 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 EON32565.1 - 0.00033 20.7 0.2 0.00075 19.5 0.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 EON32565.1 - 0.049 13.7 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON32566.1 - 2.3e-22 79.0 0.0 4.6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON32566.1 - 1e-20 74.5 0.1 1.3e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32566.1 - 2e-15 57.4 0.0 3.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 EON32566.1 - 0.0019 17.9 0.1 0.0079 15.9 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_2 PF08028.11 EON32566.1 - 0.0098 16.2 1.3 0.016 15.5 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_TTP_11 PF16460.5 EON32566.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like Acyl-CoA_dh_1 PF00441.24 EON32567.1 - 6.2e-25 88.2 2.0 1e-24 87.4 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32567.1 - 1.7e-12 48.0 0.0 4.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON32567.1 - 4.2e-09 36.5 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32567.1 - 1.2e-06 28.8 1.6 1.2e-06 28.8 1.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF350 PF03994.14 EON32568.1 - 7.7e-26 90.0 9.7 8.7e-13 48.2 0.9 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) DUF373 PF04123.13 EON32568.1 - 0.0092 15.5 1.0 0.0094 15.4 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF3040 PF11239.8 EON32568.1 - 1.8 8.9 13.8 5.4 7.4 1.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) Polyketide_cyc2 PF10604.9 EON32569.1 - 9.4e-17 61.6 0.5 1.1e-16 61.4 0.5 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON32569.1 - 8.2e-07 29.3 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EON32569.1 - 0.0073 16.5 0.2 0.01 16.1 0.2 1.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Glycos_transf_3 PF00591.21 EON32569.1 - 0.089 12.4 0.1 0.59 9.7 0.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase family, a/b domain Hydrolase_6 PF13344.6 EON32570.1 - 4.5e-21 74.9 0.0 1.9e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON32570.1 - 4e-17 62.0 0.1 8.9e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EON32570.1 - 1.3e-10 41.9 2.2 1.7e-06 28.5 0.6 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EON32570.1 - 6.5e-07 29.6 0.0 4.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EON32570.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ceramidase PF05875.12 EON32570.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Ceramidase MoeA_N PF03453.17 EON32571.1 - 3.6e-40 137.3 3.8 3.6e-40 137.3 3.8 2.0 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EON32571.1 - 3e-25 88.6 0.1 6.9e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EON32571.1 - 3.9e-18 65.4 0.1 9.7e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PS_Dcarbxylase PF02666.15 EON32572.1 - 4e-31 108.1 0.0 5.5e-30 104.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase CDP-OH_P_transf PF01066.21 EON32573.1 - 6.9e-10 39.6 3.6 6.9e-10 39.6 3.6 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1129 PF06570.11 EON32573.1 - 0.22 11.0 0.5 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4395 PF14340.6 EON32573.1 - 5.2 7.4 15.8 0.096 13.0 1.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4395) AAA PF00004.29 EON32574.1 - 4.4e-54 182.4 0.0 2.5e-40 138.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON32574.1 - 7.7e-20 70.4 9.9 6.5e-11 41.9 3.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EON32574.1 - 3.9e-11 43.0 0.1 2.4e-10 40.5 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 EON32574.1 - 5.6e-07 30.1 8.7 0.00075 19.9 0.6 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EON32574.1 - 6.6e-07 29.4 0.3 0.0002 21.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EON32574.1 - 1.1e-06 29.0 1.0 0.089 13.1 0.0 4.4 3 1 1 4 4 4 2 AAA domain AAA_33 PF13671.6 EON32574.1 - 2.1e-06 28.0 0.0 0.071 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 EON32574.1 - 4.2e-06 26.9 0.0 0.16 12.1 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.6 EON32574.1 - 8.2e-05 23.2 0.1 0.023 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EON32574.1 - 0.00012 21.9 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EON32574.1 - 0.00016 21.9 0.3 0.038 14.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EON32574.1 - 0.00035 20.3 0.6 1 9.0 0.4 3.0 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EON32574.1 - 0.00058 19.8 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 EON32574.1 - 0.0012 18.9 0.0 0.061 13.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 EON32574.1 - 0.0013 18.8 0.3 2.2 8.3 0.2 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EON32574.1 - 0.0015 18.7 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EON32574.1 - 0.0017 18.2 0.1 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Molydop_binding PF01568.21 EON32574.1 - 0.0026 17.8 0.4 0.046 13.7 0.2 2.4 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain AAA_25 PF13481.6 EON32574.1 - 0.0027 17.3 6.2 0.32 10.6 0.1 4.2 3 1 1 4 4 4 1 AAA domain ABC_tran PF00005.27 EON32574.1 - 0.0057 17.2 0.0 0.6 10.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 EON32574.1 - 0.007 16.1 0.2 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EON32574.1 - 0.0071 16.7 0.0 0.46 10.9 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 EON32574.1 - 0.009 16.3 2.1 1.8 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EON32574.1 - 0.0092 15.7 0.0 1.5 8.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 EON32574.1 - 0.02 14.1 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EON32574.1 - 0.022 14.3 0.2 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EON32574.1 - 0.022 14.2 0.6 0.65 9.3 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EON32574.1 - 0.028 14.1 0.0 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EON32574.1 - 0.028 13.2 0.0 5.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 EON32574.1 - 0.035 14.0 0.0 9.8 6.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EON32574.1 - 0.045 13.7 3.2 6.5 6.7 0.2 3.1 4 0 0 4 4 2 0 NACHT domain NTPase_1 PF03266.15 EON32574.1 - 0.047 13.6 1.5 1 9.3 0.3 2.5 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 EON32574.1 - 0.09 12.5 0.0 24 4.6 0.0 3.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EON32574.1 - 0.19 11.5 0.0 0.71 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AA_kinase PF00696.28 EON32574.1 - 0.2 11.2 1.7 0.28 10.8 0.3 1.9 2 0 0 2 2 2 0 Amino acid kinase family cobW PF02492.19 EON32574.1 - 0.3 10.6 2.5 3.4 7.2 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.16 EON32575.1 - 7.9e-49 166.5 48.6 7.9e-49 166.5 48.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32575.1 - 2.2e-13 49.9 38.0 1.2e-10 40.9 12.0 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 EON32575.1 - 0.0061 15.2 45.2 0.016 13.8 15.6 3.9 2 1 1 4 4 4 2 MFS/sugar transport protein TM_helix PF05552.12 EON32575.1 - 0.43 10.6 4.7 2.4 8.2 0.4 3.7 2 0 0 2 2 2 0 Conserved TM helix Usp PF00582.26 EON32576.1 - 5.6e-22 78.8 9.6 2.4e-16 60.5 1.0 2.6 2 1 0 2 2 2 2 Universal stress protein family TetR_N PF00440.23 EON32577.1 - 8.3e-10 38.3 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 EON32577.1 - 6.8e-08 32.5 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Fer2 PF00111.27 EON32578.1 - 7.8e-11 41.8 4.3 1.5e-10 40.8 4.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON32578.1 - 0.00027 21.5 0.3 0.0036 17.9 0.3 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 EON32578.1 - 0.00088 19.3 0.1 0.002 18.1 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 EON32578.1 - 0.0019 18.5 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EON32578.1 - 0.0053 16.9 0.2 0.27 11.3 0.1 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF4314 PF14192.6 EON32578.1 - 0.1 12.5 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) Acetyltransf_1 PF00583.25 EON32579.1 - 8.7e-13 48.5 0.0 5.3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON32579.1 - 8.3e-08 32.6 0.0 0.011 16.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON32579.1 - 1.6e-05 24.8 0.0 0.032 14.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON32579.1 - 0.00011 22.9 0.0 0.2 12.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON32579.1 - 0.0038 17.3 0.0 0.93 9.7 0.0 2.5 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.10 EON32579.1 - 0.0053 16.7 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein CoA_transf_3 PF02515.17 EON32580.1 - 7.7e-180 597.8 0.5 7e-100 334.7 0.1 2.0 2 0 0 2 2 2 2 CoA-transferase family III Aldedh PF00171.22 EON32581.1 - 6.5e-153 509.5 0.0 7.3e-153 509.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Thiolase_N PF00108.23 EON32582.1 - 0.0053 16.1 1.5 0.017 14.5 1.5 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain DUF35_N PF12172.8 EON32583.1 - 7.2e-12 44.9 2.2 1.2e-11 44.2 2.2 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) OB_aCoA_assoc PF01796.17 EON32583.1 - 4.7e-11 42.5 1.0 5.5e-11 42.3 0.3 1.5 2 0 0 2 2 2 1 DUF35 OB-fold domain, acyl-CoA-associated DUF3168 PF11367.8 EON32583.1 - 0.0077 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3168) TackOD1 PF18551.1 EON32583.1 - 0.059 13.0 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 TLP1_add_C PF18313.1 EON32585.1 - 8e-18 64.2 2.3 1.6e-17 63.2 2.3 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 EON32585.1 - 0.05 13.3 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain DUF222 PF02720.17 EON32587.1 - 3e-11 43.4 0.1 3.2e-11 43.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF222) AMP-binding PF00501.28 EON32588.1 - 2.9e-81 273.2 0.0 3.4e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON32588.1 - 3.8e-12 47.0 0.7 1.2e-11 45.4 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Rieske PF00355.26 EON32590.1 - 1.9e-18 66.2 0.0 3.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 EON32590.1 - 3e-17 63.3 0.2 9.4e-17 61.7 0.2 1.7 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) TetR_N PF00440.23 EON32591.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 EON32591.1 - 4.6e-05 23.3 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF2828 PF11443.8 EON32591.1 - 0.24 9.5 0.0 0.29 9.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1353 PF07087.11 EON32592.1 - 3.8e-19 68.2 0.0 1.3e-18 66.4 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1353) PQQ_2 PF13360.6 EON32594.1 - 1.8e-08 34.2 10.5 0.00017 21.3 5.8 3.9 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 EON32594.1 - 1.9e-05 24.4 1.6 0.18 11.8 0.0 4.2 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 EON32594.1 - 1.3 9.6 7.3 47 4.7 0.1 5.2 5 0 0 5 5 5 0 PQQ-like domain NAD-GH PF10712.9 EON32595.1 - 2e-156 521.8 65.8 1.7e-153 512.2 65.8 2.0 1 1 0 1 1 1 1 NAD-specific glutamate dehydrogenase HSP70 PF00012.20 EON32596.1 - 1.9e-248 825.6 19.0 5.2e-246 817.6 19.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EON32596.1 - 1.2e-18 67.1 2.0 1.2e-18 67.1 2.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 EON32596.1 - 0.005 16.1 2.2 0.55 9.4 0.1 2.9 2 1 1 3 3 3 2 StbA protein FtsA PF14450.6 EON32596.1 - 0.042 14.3 5.1 10 6.6 0.0 3.8 3 1 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 EON32596.1 - 2.6 7.7 4.5 1 9.0 0.5 2.3 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain GrpE PF01025.19 EON32597.1 - 4.5e-28 98.0 0.0 7.8e-28 97.2 0.0 1.3 1 1 0 1 1 1 1 GrpE DnaJ_C PF01556.18 EON32598.1 - 1.8e-38 132.0 0.0 7.1e-38 130.0 0.0 1.8 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EON32598.1 - 1.5e-24 85.9 0.5 2.1e-24 85.4 0.5 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EON32598.1 - 6.9e-12 45.6 15.1 1.2e-11 44.8 15.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EON32598.1 - 0.001 19.0 13.0 0.062 13.3 3.9 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 EON32598.1 - 0.019 15.1 3.0 0.019 15.1 3.0 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5351) MerR_1 PF13411.6 EON32599.1 - 1.5e-17 63.4 0.0 2.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EON32599.1 - 1.2e-11 44.2 1.1 1.7e-11 43.7 0.2 1.8 2 0 0 2 2 2 1 MerR family regulatory protein MerR_2 PF13591.6 EON32599.1 - 4.7e-09 36.0 0.1 5.4e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein Secretin_N PF03958.17 EON32599.1 - 0.0085 16.5 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial type II/III secretion system short domain LPP PF04728.13 EON32599.1 - 0.019 15.3 0.3 0.047 14.1 0.1 1.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 EON32599.1 - 0.067 13.3 2.2 0.18 11.9 2.1 1.7 1 1 1 2 2 2 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 EON32599.1 - 0.11 12.7 0.4 0.24 11.5 0.4 1.6 1 1 0 1 1 1 0 MbeD/MobD like Polyketide_cyc2 PF10604.9 EON32600.1 - 2e-12 47.6 1.8 2.3e-12 47.4 1.8 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON32600.1 - 0.0051 17.0 1.1 0.014 15.6 1.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EON32600.1 - 0.0066 16.7 0.1 0.008 16.4 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Orai-1 PF07856.12 EON32601.1 - 0.0024 17.6 0.2 0.004 16.9 0.2 1.3 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF3149 PF11346.8 EON32601.1 - 0.087 12.5 4.8 2.1 8.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) FAD_binding_6 PF00970.24 EON32603.1 - 8.8e-12 45.3 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EON32603.1 - 3.9e-11 43.6 0.0 8.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EON32603.1 - 4.1e-08 33.8 0.1 8.7e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 EON32603.1 - 0.00018 21.4 0.3 0.00027 20.9 0.3 1.3 1 0 0 1 1 1 1 Protoglobin Amidohydro_2 PF04909.14 EON32604.1 - 5.8e-27 95.2 0.3 6.9e-27 95.0 0.3 1.3 1 1 0 1 1 1 1 Amidohydrolase Pkinase PF00069.25 EON32605.1 - 1.2e-33 116.7 0.0 1.8e-33 116.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON32605.1 - 1.7e-26 93.1 0.0 2.1e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON32605.1 - 0.025 14.5 4.1 0.04 13.8 0.4 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON32605.1 - 0.063 12.1 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase F420H2_quin_red PF04075.14 EON32606.1 - 3.1e-20 72.6 0.0 3.6e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase FAD-oxidase_C PF02913.19 EON32607.1 - 1.4e-59 201.8 0.1 2e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EON32607.1 - 3e-42 143.6 0.8 3e-42 143.6 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain GGDEF PF00990.21 EON32608.1 - 2.6e-29 102.1 0.1 4.1e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 EON32608.1 - 0.0017 18.6 1.2 0.0017 18.6 1.2 2.5 2 2 0 2 2 2 1 GGDEF-like domain DUF1700 PF08006.11 EON32608.1 - 6.9 6.2 5.6 12 5.3 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) HTH_1 PF00126.27 EON32609.1 - 1.3e-16 60.3 0.1 2.2e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EON32609.1 - 8e-15 54.8 0.7 8e-15 54.8 0.7 1.7 2 0 0 2 2 2 1 LysR substrate binding domain AidB_N PF18158.1 EON32610.1 - 6.3e-59 198.4 0.2 6.3e-59 198.4 0.2 1.7 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON32610.1 - 2.2e-24 86.4 4.4 3.8e-24 85.6 4.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON32610.1 - 6.3e-15 55.2 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32610.1 - 2.1e-06 28.0 4.3 2.1e-06 28.0 4.3 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_C_12 PF16914.5 EON32611.1 - 1.1e-41 141.2 0.6 1.7e-41 140.6 0.6 1.3 1 0 0 1 1 1 1 Bacterial transcriptional repressor C-terminal TetR_N PF00440.23 EON32611.1 - 2.1e-09 37.0 0.1 6.6e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family ResIII PF04851.15 EON32612.1 - 4e-12 46.5 0.0 6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EON32612.1 - 8.9e-07 29.2 0.0 2.9e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain RP1-2 PF12042.8 EON32612.1 - 1.2 9.0 4.6 2 8.2 4.6 1.3 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain DUF3375 PF11855.8 EON32613.1 - 4.4e-71 240.2 19.8 5.6e-71 239.9 19.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) ThiS PF02597.20 EON32613.1 - 0.035 14.7 0.7 29 5.4 0.1 3.6 4 0 0 4 4 4 0 ThiS family DUF1192 PF06698.11 EON32613.1 - 0.73 9.9 5.2 2.3 8.3 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4194 PF13835.6 EON32614.1 - 1.4e-25 89.9 1.3 1.7e-25 89.7 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) AAA_29 PF13555.6 EON32615.1 - 8.1e-14 51.1 0.3 1.9e-13 50.0 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EON32615.1 - 8.1e-13 48.4 0.0 2.5e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EON32615.1 - 0.0026 18.3 0.1 0.047 14.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EON32615.1 - 0.0047 17.4 0.0 0.74 10.3 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EON32615.1 - 0.014 15.3 0.1 0.059 13.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MukB PF04310.12 EON32615.1 - 0.026 14.4 0.5 0.069 12.9 0.5 1.7 1 0 0 1 1 1 0 MukB N-terminal Terpene_synth_C PF03936.16 EON32615.1 - 0.081 12.2 0.1 0.6 9.4 0.0 2.3 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain GAT PF03127.14 EON32615.1 - 0.15 12.4 0.1 3.4 8.0 0.2 3.0 3 0 0 3 3 3 0 GAT domain PUF PF00806.19 EON32615.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat AAA_16 PF13191.6 EON32615.1 - 0.22 11.9 0.0 0.22 11.9 0.0 3.9 3 2 0 3 3 3 0 AAA ATPase domain APG6_N PF17675.1 EON32615.1 - 2.5 8.7 8.9 4.6 7.8 1.4 3.8 3 1 1 4 4 4 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EON32615.1 - 5.8 7.2 7.9 6.3 7.1 0.1 3.8 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF2220 PF09983.9 EON32616.1 - 9.4e-33 113.1 0.0 1.5e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF3322 PF11795.8 EON32616.1 - 7.8e-21 74.9 2.9 1.3e-20 74.2 2.9 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) Glyco_hydro_16 PF00722.21 EON32617.1 - 5.8e-13 48.7 0.0 9.2e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TetR_N PF00440.23 EON32618.1 - 9.2e-15 54.2 0.3 1.6e-14 53.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EON32618.1 - 3.3e-09 37.1 7.9 3.3e-09 37.1 7.9 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_16 PF17920.1 EON32618.1 - 0.025 14.8 2.6 0.057 13.7 2.6 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_AsnC-type PF13404.6 EON32618.1 - 0.046 13.6 1.1 0.12 12.2 0.1 2.3 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain TetR_C_15 PF17918.1 EON32618.1 - 0.7 10.7 6.7 0.49 11.2 4.0 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ArabFuran-catal PF09206.11 EON32619.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic Bac_luciferase PF00296.20 EON32620.1 - 7.8e-52 176.6 4.6 1.4e-51 175.8 4.6 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase PPDK_N PF01326.19 EON32621.1 - 5.5e-52 177.1 4.8 1.1e-34 120.2 6.0 3.4 2 1 1 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EON32621.1 - 1.6e-18 66.2 2.3 2.2e-18 65.7 0.3 2.3 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Globin PF00042.22 EON32622.1 - 2.2e-11 44.3 0.0 6.5e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Globin MLTR_LBD PF17765.1 EON32623.1 - 2.1e-54 184.1 1.1 2.1e-54 184.1 1.1 1.6 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 EON32623.1 - 1.6e-14 53.9 2.2 6.5e-14 52.0 2.2 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EON32623.1 - 2.5e-08 33.9 0.4 8.3e-07 29.0 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 EON32623.1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_zinc_N PF00107.26 EON32624.1 - 8.2e-22 77.6 0.0 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON32624.1 - 2.6e-21 75.5 2.3 2.6e-21 75.5 2.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EON32624.1 - 3.7e-06 26.6 1.3 6.3e-06 25.8 1.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON32624.1 - 0.0032 18.5 0.0 0.0096 17.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON32624.1 - 0.11 11.8 2.0 0.17 11.2 2.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EON32625.1 - 8.5e-36 123.6 76.7 3.4e-31 108.5 49.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EON32625.1 - 0.00014 21.3 51.4 0.00019 20.9 51.4 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EON32625.1 - 0.034 13.0 23.5 0.34 9.7 12.4 2.3 1 1 1 2 2 2 0 MFS_1 like family Cupin_2 PF07883.11 EON32626.1 - 6.8e-11 41.7 2.4 1.1e-10 41.0 1.9 1.6 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.19 EON32626.1 - 0.0034 17.3 0.4 0.0047 16.8 0.4 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_7 PF12973.7 EON32626.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_3 PF05899.12 EON32626.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ADH_zinc_N_2 PF13602.6 EON32627.1 - 1.1e-28 101.0 0.0 2e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EON32627.1 - 9.7e-14 51.5 0.5 5.2e-13 49.1 0.5 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON32627.1 - 7e-11 42.0 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CbiJ PF02571.14 EON32627.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK YjeF_N PF03853.15 EON32627.1 - 0.11 12.4 1.8 0.28 11.0 1.8 1.5 1 1 0 1 1 1 0 YjeF-related protein N-terminus Abhydrolase_1 PF00561.20 EON32628.1 - 4.3e-19 69.2 0.1 7.3e-13 48.8 0.3 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON32628.1 - 8.5e-16 57.9 0.1 1.1e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON32628.1 - 1.7e-14 55.0 5.3 2.3e-14 54.6 5.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON32628.1 - 0.00012 22.3 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 EON32628.1 - 0.00039 20.5 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 EON32628.1 - 0.0025 17.4 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 EON32628.1 - 0.016 14.8 0.1 0.18 11.4 0.1 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EON32628.1 - 0.043 13.3 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 EON32628.1 - 0.054 13.2 0.0 0.29 10.8 0.0 2.1 1 1 1 2 2 2 0 PGAP1-like protein SBP_bac_11 PF13531.6 EON32628.1 - 0.1 12.3 0.9 10 5.8 0.3 2.2 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein adh_short PF00106.25 EON32629.1 - 3.6e-33 114.7 0.1 5.2e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32629.1 - 9.4e-22 77.7 0.3 1.4e-21 77.2 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EON32629.1 - 3.9e-09 36.7 0.5 5.2e-09 36.3 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EON32629.1 - 4.2e-06 26.1 0.2 5.9e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EON32629.1 - 9e-06 25.7 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32629.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EON32629.1 - 0.005 16.0 0.1 0.0061 15.7 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EON32629.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Abhydrolase_1 PF00561.20 EON32630.1 - 1.2e-26 93.9 0.6 7.1e-26 91.4 0.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON32630.1 - 3.6e-19 69.0 0.1 4.7e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON32630.1 - 3.1e-18 67.2 3.9 3.9e-18 66.9 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EON32630.1 - 9.5e-08 31.9 0.2 0.00035 20.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EON32630.1 - 1.1e-07 31.6 0.2 0.00037 20.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EON32630.1 - 0.00028 21.0 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EON32630.1 - 0.00073 19.3 0.1 0.0044 16.7 0.1 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EON32630.1 - 0.0013 18.4 0.1 0.0042 16.7 0.1 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EON32630.1 - 0.0079 16.1 0.0 0.054 13.4 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 EON32630.1 - 0.0092 15.5 1.8 0.74 9.3 0.4 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase LIP PF03583.14 EON32630.1 - 0.013 14.9 1.4 3.2 7.0 1.0 2.1 2 0 0 2 2 2 0 Secretory lipase Thioesterase PF00975.20 EON32630.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 EON32630.1 - 0.025 14.3 0.0 0.37 10.5 0.0 2.3 1 1 1 2 2 2 0 PGAP1-like protein DUF2048 PF09752.9 EON32630.1 - 0.052 12.6 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 Abhydrolase domain containing 18 TetR_N PF00440.23 EON32631.1 - 0.00026 20.7 0.2 0.0025 17.6 0.1 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON32631.1 - 0.018 15.2 1.9 0.019 15.1 0.8 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MaoC_dehydratas PF01575.19 EON32632.1 - 3.1e-08 33.2 0.1 3.7e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON32632.1 - 5.2e-06 26.6 0.1 6.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase CPSase_L_D2 PF02786.17 EON32633.1 - 1.8e-60 204.1 0.1 4.2e-60 202.9 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EON32633.1 - 3.7e-35 120.3 0.0 8.5e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Carboxyl_trans PF01039.22 EON32633.1 - 5.5e-35 120.9 0.3 8.8e-35 120.3 0.3 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Biotin_carb_N PF00289.22 EON32633.1 - 7.9e-31 106.9 0.4 1.9e-30 105.6 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain ACC_central PF08326.12 EON32633.1 - 5.1e-12 44.9 0.0 1.3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 EON32633.1 - 4.2e-11 42.5 0.1 1.1e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EON32633.1 - 1.1e-08 34.8 0.0 2.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EON32633.1 - 8.4e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EON32633.1 - 0.0015 18.3 0.0 2 8.3 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like LAL_C2 PF18603.1 EON32633.1 - 0.018 15.2 0.1 0.092 12.9 0.1 2.3 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 ATP-grasp_5 PF13549.6 EON32633.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.6 EON32633.1 - 0.054 14.2 1.2 6 7.6 0.1 3.2 3 0 0 3 3 2 0 HlyD family secretion protein ATP-grasp_4 PF13535.6 EON32633.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Polyketide_cyc2 PF10604.9 EON32634.1 - 7.4e-16 58.7 4.0 9.1e-16 58.4 4.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON32634.1 - 1.9e-06 28.1 1.4 3.3e-06 27.4 1.4 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EON32634.1 - 0.00011 22.4 0.9 0.00013 22.2 0.9 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein SelR PF01641.18 EON32635.1 - 2.3e-47 160.0 0.0 3e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain PMSR PF01625.21 EON32636.1 - 2.2e-54 183.8 0.0 2.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase ParD_like PF11903.8 EON32637.1 - 6.9e-15 54.9 3.1 7.1e-15 54.8 2.1 1.7 2 1 0 2 2 2 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system Zeta_toxin PF06414.12 EON32638.1 - 4.6e-16 58.7 0.1 6.2e-15 55.0 0.1 2.0 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EON32638.1 - 1.5e-09 38.2 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON32638.1 - 0.02 15.3 0.0 0.023 15.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 EON32638.1 - 0.02 14.8 0.1 0.096 12.6 0.1 2.4 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 EON32638.1 - 0.021 14.5 0.0 0.055 13.1 0.0 1.6 1 1 1 2 2 2 0 Dephospho-CoA kinase AAA_29 PF13555.6 EON32638.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EON32638.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON32638.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF1937 PF09152.10 EON32638.1 - 0.12 13.2 0.1 0.68 10.8 0.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF1937) AAA_22 PF13401.6 EON32638.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain PfkB PF00294.24 EON32639.1 - 1.2e-54 185.7 9.0 1.4e-54 185.5 9.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EON32639.1 - 0.00018 21.0 1.3 0.00023 20.6 0.1 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase XdhC_C PF13478.6 EON32639.1 - 0.017 15.6 0.2 0.32 11.5 0.0 2.7 2 1 1 3 3 3 0 XdhC Rossmann domain Nitro_FeMo-Co PF02579.17 EON32639.1 - 0.093 13.1 0.7 0.31 11.4 0.7 1.9 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Amidohydro_2 PF04909.14 EON32639.1 - 0.43 10.3 3.5 1.7 8.3 0.6 2.1 1 1 1 2 2 2 0 Amidohydrolase Flavin_Reduct PF01613.18 EON32640.1 - 4.9e-18 65.6 0.0 6.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Y_phosphatase3 PF13350.6 EON32641.1 - 1.8e-36 126.3 0.0 2e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EON32641.1 - 0.00072 19.2 0.0 0.00095 18.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EON32641.1 - 0.064 13.1 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 EON32641.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 EON32641.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 EON32641.1 - 0.25 11.5 0.1 0.35 11.0 0.1 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF2470 PF10615.9 EON32642.1 - 1.2e-16 61.1 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Peripla_BP_3 PF13377.6 EON32643.1 - 1.3e-36 126.4 3.2 1.6e-36 126.2 1.3 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EON32643.1 - 1.9e-24 86.6 0.0 2.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EON32643.1 - 8.5e-16 58.3 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 EON32643.1 - 3.1e-10 39.7 0.1 1.4e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.10 EON32643.1 - 3.6e-05 23.5 1.1 0.0015 18.3 0.1 2.9 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_38 PF13936.6 EON32643.1 - 0.00026 20.7 0.7 0.028 14.2 0.4 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON32643.1 - 0.0027 17.5 0.2 0.12 12.2 0.2 3.0 2 1 1 3 3 3 1 Homeodomain-like domain HTH_AraC PF00165.23 EON32643.1 - 0.0066 16.5 0.0 1.8 8.8 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family MarR PF01047.22 EON32643.1 - 0.023 14.6 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 MarR family TetR_N PF00440.23 EON32643.1 - 0.12 12.2 0.2 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_31 PF13560.6 EON32643.1 - 0.2 12.0 5.4 3.4 8.1 0.4 3.4 1 1 1 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 EON32643.1 - 0.26 11.2 3.0 0.53 10.2 0.3 2.8 2 1 1 3 3 3 0 MarR family Acyl-CoA_dh_1 PF00441.24 EON32644.1 - 2.4e-31 109.0 0.1 3.5e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32644.1 - 1.7e-27 96.3 0.1 3.7e-27 95.2 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON32644.1 - 8.6e-26 90.0 0.0 1.5e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32644.1 - 3.1e-09 37.2 0.0 4.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON32644.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal ANTAR PF03861.14 EON32645.1 - 1.1e-17 63.5 1.6 2.3e-17 62.6 0.3 2.2 2 0 0 2 2 2 1 ANTAR domain GAF_2 PF13185.6 EON32645.1 - 2e-10 41.1 0.4 2.7e-10 40.7 0.4 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EON32645.1 - 0.0002 22.0 0.0 0.0003 21.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain STAS PF01740.21 EON32646.1 - 7.7e-09 35.2 0.0 9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EON32646.1 - 1.4e-07 31.7 0.2 2.3e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 STAS domain Sigma70_r4 PF04545.16 EON32647.1 - 9.5e-17 60.3 4.1 1.3e-15 56.6 3.6 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EON32647.1 - 1.6e-14 53.4 0.1 4.1e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EON32647.1 - 9.2e-14 51.3 0.3 1.4e-11 44.3 0.1 2.4 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 EON32647.1 - 5.4e-11 42.0 0.5 7.9e-10 38.3 0.5 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 KORA PF16509.5 EON32647.1 - 4.4e-06 26.9 0.1 8.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor MarR_2 PF12802.7 EON32647.1 - 0.00016 21.5 0.2 0.031 14.1 0.1 2.6 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 EON32647.1 - 0.0002 21.0 0.1 0.0023 17.7 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 EON32647.1 - 0.00021 21.0 0.9 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain Sigma70_ECF PF07638.11 EON32647.1 - 0.0018 18.2 0.3 0.0032 17.4 0.3 1.5 1 0 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 EON32647.1 - 0.0026 17.3 0.4 0.025 14.1 0.1 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 EON32647.1 - 0.0029 17.1 0.5 0.0059 16.1 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family MarR PF01047.22 EON32647.1 - 0.0033 17.3 0.1 0.0085 16.0 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.6 EON32647.1 - 0.0033 17.1 0.9 0.041 13.7 1.3 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EON32647.1 - 0.0055 16.6 0.4 0.014 15.3 0.4 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF722 PF05263.11 EON32647.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF722) YdaS_antitoxin PF15943.5 EON32647.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 EON32647.1 - 0.013 15.5 0.1 0.037 14.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_26 PF13443.6 EON32647.1 - 0.034 14.6 0.1 0.095 13.1 0.1 1.6 2 0 0 2 2 1 0 Cro/C1-type HTH DNA-binding domain Phage_antitermQ PF06530.12 EON32647.1 - 0.043 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q DUF134 PF02001.16 EON32647.1 - 0.052 14.1 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 UPF0122 PF04297.14 EON32647.1 - 0.052 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DUF3509 PF12021.8 EON32647.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) HTH_28 PF13518.6 EON32647.1 - 0.082 13.0 0.0 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 EON32647.1 - 0.096 12.5 1.6 0.53 10.1 0.1 2.5 2 0 0 2 2 2 0 HTH DNA binding domain DprA_WH PF17782.1 EON32647.1 - 0.096 12.8 0.8 9.5 6.4 0.0 2.7 2 0 0 2 2 2 0 DprA winged helix domain HTH_5 PF01022.20 EON32647.1 - 0.11 12.4 0.1 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_31 PF13560.6 EON32647.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.6 3 1 0 3 3 2 0 Helix-turn-helix domain ADH_N PF08240.12 EON32648.1 - 4.6e-27 94.1 0.2 7.7e-27 93.3 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON32648.1 - 3.9e-15 56.0 1.0 3.9e-12 46.3 0.5 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EON32648.1 - 1.4e-12 47.3 0.7 1.4e-12 47.3 0.7 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 EON32648.1 - 3.3e-06 26.6 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EON32648.1 - 0.00029 20.2 1.2 0.00048 19.5 1.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EON32648.1 - 0.00035 20.8 0.2 0.00063 20.0 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 EON32648.1 - 0.003 17.5 0.3 0.0047 16.8 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON32648.1 - 0.0044 16.3 0.8 0.006 15.9 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EON32648.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 EON32648.1 - 0.017 15.3 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_25 PF13649.6 EON32648.1 - 0.079 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EON32648.1 - 0.15 12.8 0.0 0.37 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Phage_holin_3_6 PF07332.11 EON32649.1 - 0.00019 21.4 1.0 0.00028 20.9 1.0 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 EON32649.1 - 0.022 13.6 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2776 PF10951.8 EON32649.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) DUF3040 PF11239.8 EON32649.1 - 0.16 12.3 6.6 0.34 11.2 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2530 PF10745.9 EON32649.1 - 0.17 12.1 7.4 0.23 11.7 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) CRPA PF05745.11 EON32649.1 - 0.26 11.3 0.4 0.4 10.7 0.4 1.2 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) FAM176 PF14851.6 EON32649.1 - 2.7 7.7 4.3 14 5.3 0.0 2.3 1 1 1 2 2 2 0 FAM176 family HCV_NS4a PF01006.20 EON32649.1 - 2.9 7.7 5.3 33 4.3 0.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a HATPase_c_2 PF13581.6 EON32650.1 - 0.0062 16.5 0.1 0.0099 15.8 0.1 1.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain Glyco_tranf_2_3 PF13641.6 EON32651.1 - 4.9e-09 36.4 0.3 1.5e-08 34.8 0.2 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON32651.1 - 2.3e-06 27.3 0.0 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 EON32651.1 - 3.6e-05 23.3 0.2 6.4e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 EON32651.1 - 4.7e-05 23.2 0.0 7.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EON32651.1 - 0.0035 17.3 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tran_28_C PF04101.16 EON32652.1 - 0.0088 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 EON32653.1 - 2.6e-19 69.4 0.0 3.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON32653.1 - 6.9e-19 68.5 1.5 1.1e-18 67.8 1.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EON32653.1 - 1.4e-17 64.4 0.0 2.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON32653.1 - 3.2e-06 27.7 7.8 3.2e-06 27.7 7.8 2.4 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EON32653.1 - 0.011 16.1 0.0 0.047 14.1 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EON32653.1 - 0.17 11.6 0.1 0.29 10.8 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 EON32654.1 - 9.5e-09 35.5 2.9 2.2e-08 34.3 2.9 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ANTAR PF03861.14 EON32655.1 - 1.1e-13 50.8 0.3 2.2e-13 49.8 0.3 1.6 1 0 0 1 1 1 1 ANTAR domain PAS_3 PF08447.12 EON32655.1 - 1.7e-12 47.4 0.1 3.3e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EON32655.1 - 0.0016 18.7 0.3 0.0034 17.6 0.3 1.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EON32655.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EON32655.1 - 0.073 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 PAS domain adh_short_C2 PF13561.6 EON32657.1 - 7.5e-59 199.1 0.0 9.1e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON32657.1 - 3e-52 176.9 0.0 3.9e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON32657.1 - 3.9e-10 39.9 0.1 5.2e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32657.1 - 0.017 14.6 0.2 0.023 14.2 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON32657.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LIP PF03583.14 EON32658.1 - 9e-46 156.5 0.0 1.3e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peripla_BP_2 PF01497.18 EON32659.1 - 7.9e-19 68.2 0.0 1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HTH_5 PF01022.20 EON32660.1 - 2.3e-09 37.0 0.1 5.6e-09 35.7 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON32660.1 - 4.7e-09 36.2 0.1 7.6e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EON32660.1 - 1.5e-05 24.8 0.4 2.3e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 EON32660.1 - 0.0023 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EON32660.1 - 0.0039 17.0 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EON32660.1 - 0.0047 16.9 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 EON32660.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 CodY helix-turn-helix domain Rrf2 PF02082.20 EON32660.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator GntR PF00392.21 EON32660.1 - 0.059 13.0 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HxlR PF01638.17 EON32660.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix RP-C PF03428.13 EON32660.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 Replication protein C N-terminal domain Cation_efflux PF01545.21 EON32661.1 - 9.1e-11 41.9 12.2 4.4e-10 39.6 12.0 1.8 1 1 0 1 1 1 1 Cation efflux family Bac_rhodopsin PF01036.18 EON32661.1 - 0.0093 15.6 1.9 0.013 15.1 0.9 1.7 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein FCD PF07729.12 EON32662.1 - 8.3e-28 97.3 10.4 1.4e-27 96.6 10.4 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON32662.1 - 2.1e-16 59.3 1.3 3.2e-16 58.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 EON32662.1 - 0.047 13.4 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 EON32662.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain MFS_1 PF07690.16 EON32663.1 - 1.3e-26 93.4 50.6 1.3e-26 93.4 50.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EON32663.1 - 0.0015 17.6 6.3 0.0015 17.6 6.3 2.5 2 1 1 3 3 3 1 Nucleoside H+ symporter MFS_1_like PF12832.7 EON32663.1 - 1.9 7.2 19.8 1.8 7.4 2.7 2.4 1 1 1 2 2 2 0 MFS_1 like family Amino_oxidase PF01593.24 EON32664.1 - 1.9e-41 142.8 0.9 2.6e-41 142.4 0.9 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EON32664.1 - 5.3e-13 49.3 9.8 3.2e-12 46.7 9.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON32664.1 - 1.9e-10 40.8 0.3 1.9e-10 40.8 0.3 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON32664.1 - 8.2e-09 35.1 0.7 0.00079 18.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32664.1 - 2.2e-08 34.5 0.8 0.00076 20.0 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON32664.1 - 5.2e-08 32.7 2.1 5.6e-07 29.3 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON32664.1 - 1.3e-06 27.8 4.2 1.1e-05 24.7 2.3 2.7 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 EON32664.1 - 7.8e-06 24.8 1.1 0.0055 15.5 0.6 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 EON32664.1 - 0.00028 20.3 1.6 0.001 18.4 1.9 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EON32664.1 - 0.0013 17.9 3.3 0.049 12.7 0.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON32664.1 - 0.0031 17.5 1.2 1.2 9.1 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EON32664.1 - 0.0065 15.6 4.2 0.33 10.0 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.17 EON32664.1 - 0.011 14.9 1.0 0.02 14.2 1.0 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 EON32664.1 - 0.017 13.9 0.1 0.048 12.5 0.0 1.8 2 0 0 2 2 2 0 MCRA family Pyr_redox_3 PF13738.6 EON32664.1 - 0.03 13.6 0.1 0.078 12.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON32664.1 - 0.16 10.8 3.9 3.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase PhyH PF05721.13 EON32665.1 - 3.2e-24 86.4 0.0 4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CoA_transf_3 PF02515.17 EON32666.1 - 5.4e-57 193.6 0.0 6.8e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III MaoC_dehydratas PF01575.19 EON32667.1 - 1.4e-06 27.9 0.1 0.0049 16.4 0.0 2.3 2 0 0 2 2 2 2 MaoC like domain HpcH_HpaI PF03328.14 EON32668.1 - 9.6e-43 145.9 1.3 9.6e-43 145.9 1.3 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EON32668.1 - 0.0032 16.7 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1611_N PF17396.2 EON32668.1 - 0.016 15.4 0.4 0.19 12.0 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Malate_synthase PF01274.22 EON32668.1 - 0.053 11.8 0.2 1.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Malate synthase Acyl-CoA_dh_1 PF00441.24 EON32669.1 - 4.6e-48 163.2 3.9 4.6e-48 163.2 3.9 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32669.1 - 1.6e-30 106.0 1.3 2.4e-30 105.5 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON32669.1 - 7.2e-25 87.0 0.0 1.6e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32669.1 - 1.9e-19 70.3 1.0 3.4e-19 69.5 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GntR PF00392.21 EON32670.1 - 4.9e-17 61.3 0.2 8.7e-17 60.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family UTRA PF07702.13 EON32670.1 - 6.2e-16 58.5 0.3 1.3e-15 57.5 0.3 1.5 1 0 0 1 1 1 1 UTRA domain HTH_DeoR PF08220.12 EON32670.1 - 0.00056 19.6 0.0 0.0027 17.4 0.0 2.2 1 1 1 2 2 2 1 DeoR-like helix-turn-helix domain HTH_41 PF14502.6 EON32670.1 - 0.00085 19.0 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.6 EON32670.1 - 0.014 15.4 0.0 0.053 13.5 0.0 2.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 EON32670.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_29 PF13551.6 EON32670.1 - 0.05 13.6 0.2 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.16 EON32671.1 - 3.3e-56 190.7 81.5 1.1e-44 152.8 56.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32671.1 - 5.1e-12 45.4 40.2 6.1e-08 32.0 15.6 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EON32671.1 - 1.1e-05 24.3 48.0 0.00092 17.9 21.7 3.5 4 0 0 4 4 4 3 MFS/sugar transport protein MarR_2 PF12802.7 EON32672.1 - 1.7e-09 37.4 0.1 5.1e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EON32672.1 - 4.8e-06 27.0 0.0 9.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EON32672.1 - 8.7e-06 25.2 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EON32672.1 - 1.5e-05 24.7 0.2 4.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.22 EON32672.1 - 1.6e-05 24.7 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EON32672.1 - 0.00074 19.5 0.2 0.0034 17.4 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EON32672.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 EON32672.1 - 0.0026 17.9 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EON32672.1 - 0.0047 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 EON32672.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 LexA_DNA_bind PF01726.16 EON32672.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain adh_short_C2 PF13561.6 EON32673.1 - 8.6e-26 90.9 1.9 1.2e-18 67.6 0.0 3.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON32673.1 - 1.2e-16 60.8 0.7 1.7e-06 27.6 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 EON32673.1 - 5.4e-06 26.1 1.4 1.3e-05 24.8 1.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON32673.1 - 0.099 12.5 1.0 0.23 11.3 0.9 1.6 1 1 1 2 2 2 0 KR domain Flagellin_N PF00669.20 EON32673.1 - 0.33 11.1 0.8 0.55 10.3 0.8 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DoxX PF07681.12 EON32674.1 - 9.7e-16 58.1 12.2 1e-15 58.0 5.5 2.2 2 0 0 2 2 2 2 DoxX SIP PF04954.13 EON32675.1 - 3.7e-26 92.0 0.0 7e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 EON32675.1 - 1.2e-19 70.7 0.0 2.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain ECH_2 PF16113.5 EON32676.1 - 7.1e-111 370.9 0.0 8.5e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EON32676.1 - 6.6e-27 94.4 0.1 1.3e-25 90.2 0.1 2.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EON32677.1 - 9.5e-83 277.3 0.9 1.1e-82 277.2 0.9 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON32677.1 - 4.4e-38 131.6 1.5 3.4e-35 122.1 0.5 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 EON32677.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Peptidase_S49 PF01343.18 EON32677.1 - 0.038 13.9 0.8 0.43 10.5 0.0 2.6 3 0 0 3 3 3 0 Peptidase family S49 LysR_substrate PF03466.20 EON32678.1 - 2e-32 112.2 7.8 2e-32 112.2 7.8 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EON32678.1 - 4.3e-24 84.2 1.4 4.3e-24 84.2 1.4 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family CtnDOT_TraJ PF07863.11 EON32678.1 - 0.07 13.8 0.2 0.27 11.9 0.1 2.0 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Thiolase_N PF00108.23 EON32679.1 - 5.4e-63 212.8 0.0 1.3e-62 211.5 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON32679.1 - 1.6e-41 140.8 0.1 3.5e-41 139.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON32679.1 - 0.0019 17.8 3.2 0.0031 17.1 1.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Abhydrolase_1 PF00561.20 EON32680.1 - 1.2e-29 103.7 0.0 6.3e-29 101.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON32680.1 - 1.1e-18 68.6 9.7 1.4e-18 68.3 9.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON32680.1 - 1.8e-16 60.1 0.0 4.5e-16 58.9 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EON32680.1 - 1.4e-09 37.0 0.0 1.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 EON32680.1 - 2e-06 27.8 0.1 4.8e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 EON32680.1 - 0.0065 16.0 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 EON32680.1 - 0.029 14.5 0.0 0.032 14.3 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EON32680.1 - 0.13 12.0 0.0 1.7 8.4 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family CoA_trans PF01144.23 EON32681.1 - 8.1e-69 231.3 0.3 9.4e-69 231.1 0.3 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 EON32682.1 - 1.1e-38 132.8 0.2 1.3e-38 132.5 0.2 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EON32682.1 - 0.00077 19.4 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain IF-2B PF01008.17 EON32682.1 - 0.23 10.6 0.1 0.83 8.8 0.1 1.7 2 0 0 2 2 2 0 Initiation factor 2 subunit family LysR_substrate PF03466.20 EON32683.1 - 6.1e-38 130.3 9.7 6.1e-38 130.3 9.7 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EON32683.1 - 8.2e-24 83.3 0.6 1.6e-23 82.4 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MR_MLE_C PF13378.6 EON32684.1 - 1.9e-43 148.6 0.3 2.6e-43 148.1 0.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EON32684.1 - 9.8e-19 67.7 0.8 2.7e-18 66.3 0.2 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Dioxygenase_C PF00775.21 EON32685.1 - 3.8e-62 209.0 0.0 4.8e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EON32685.1 - 7.3e-18 64.2 0.1 1e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EON32685.1 - 0.00012 22.3 0.0 0.00074 19.7 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EON32685.1 - 0.015 15.6 0.0 0.051 13.9 0.0 1.8 2 0 0 2 2 2 0 Prealbumin-like fold domain MIase PF02426.16 EON32686.1 - 4.4e-42 142.2 0.0 4.8e-42 142.0 0.0 1.0 1 0 0 1 1 1 1 Muconolactone delta-isomerase Metallophos PF00149.28 EON32687.1 - 4.1e-14 53.5 0.0 6.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON32687.1 - 6.4e-09 36.2 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FtsK_4TM PF13491.6 EON32687.1 - 1.8 8.3 13.0 0.79 9.4 8.9 2.1 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF5134 PF17197.4 EON32687.1 - 1.9 8.3 9.9 14 5.5 9.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Rhodanese PF00581.20 EON32688.1 - 1.5e-29 102.6 0.0 1.8e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain FA_desaturase PF00487.24 EON32689.1 - 1.5e-29 103.6 2.9 2.1e-29 103.1 2.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase TauD PF02668.16 EON32690.1 - 1.8e-44 152.5 0.2 2.4e-44 152.2 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sulfatase PF00884.23 EON32691.1 - 6.1e-82 275.5 0.0 8.3e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EON32691.1 - 5.6e-07 29.5 0.0 0.0037 16.9 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 EON32691.1 - 0.0045 16.9 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 EON32691.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 EON32691.1 - 0.071 12.5 0.0 6.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.17 EON32691.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 EON32691.1 - 0.15 12.8 0.0 0.51 11.1 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase SBP_bac_5 PF00496.22 EON32692.1 - 3e-67 227.2 0.1 4e-67 226.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EON32693.1 - 3e-37 128.2 10.5 3e-37 128.2 10.5 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsK_4TM PF13491.6 EON32693.1 - 0.0016 18.2 6.3 0.0016 18.2 6.3 2.8 2 2 1 3 3 3 1 4TM region of DNA translocase FtsK/SpoIIIE BPD_transp_1 PF00528.22 EON32694.1 - 4.3e-21 75.5 13.1 4.3e-21 75.5 13.1 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EON32694.1 - 0.0032 17.4 0.1 0.0032 17.4 0.1 3.1 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Bacteriocin_IId PF09221.10 EON32694.1 - 0.027 14.7 3.6 0.027 14.7 3.6 1.9 2 1 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like ABC_tran PF00005.27 EON32695.1 - 1.9e-59 200.1 0.0 2.8e-32 112.1 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON32695.1 - 1e-12 48.5 9.8 5.5e-05 23.1 0.1 4.1 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 EON32695.1 - 2.3e-11 44.0 0.0 1.3e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EON32695.1 - 3e-11 43.2 0.0 2.8e-05 23.7 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON32695.1 - 3.2e-08 33.9 4.9 0.0032 17.7 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EON32695.1 - 2.3e-05 24.0 0.7 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EON32695.1 - 3e-05 23.5 0.0 0.27 10.6 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EON32695.1 - 0.00019 21.1 1.7 2.5 7.6 0.4 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EON32695.1 - 0.00086 19.7 10.8 0.2 12.0 1.4 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EON32695.1 - 0.0011 19.2 0.1 1.2 9.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EON32695.1 - 0.0024 17.7 0.9 1.7 8.4 0.1 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein ATPase PF06745.13 EON32695.1 - 0.0073 15.7 0.8 3.4 6.9 0.0 2.4 2 0 0 2 2 2 2 KaiC AAA PF00004.29 EON32695.1 - 0.0074 16.7 0.1 6.7 7.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 EON32695.1 - 0.016 14.9 0.2 0.88 9.3 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 EON32695.1 - 0.018 15.0 0.5 6 6.7 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EON32695.1 - 0.019 14.7 0.2 5.1 6.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EON32695.1 - 0.019 14.0 0.4 3.3 6.7 0.0 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EON32695.1 - 0.021 15.3 0.0 3.4 8.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EON32695.1 - 0.039 13.2 1.1 3.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EON32695.1 - 0.039 13.5 0.3 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EON32695.1 - 0.043 13.5 4.5 3.6 7.3 1.7 3.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EON32695.1 - 0.047 12.9 2.0 3.4 6.8 0.9 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 EON32695.1 - 0.051 13.3 0.6 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 EON32695.1 - 0.079 13.0 0.2 12 6.0 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase PhoH PF02562.16 EON32695.1 - 0.091 12.2 0.3 12 5.3 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 EON32695.1 - 0.11 12.5 0.4 6.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EON32695.1 - 0.11 12.9 0.0 6.1 7.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase MobB PF03205.14 EON32695.1 - 0.14 12.1 0.3 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EON32695.1 - 0.16 11.9 5.3 5.1 7.0 0.9 2.9 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.14 EON32695.1 - 0.2 11.7 1.1 13 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EON32695.1 - 0.47 10.5 2.6 9.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Acyl-CoA_dh_1 PF00441.24 EON32696.1 - 1.1e-40 139.3 15.1 1.3e-23 83.8 8.5 2.5 2 1 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32696.1 - 1.4e-29 103.0 0.8 2.7e-19 69.9 0.0 3.3 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON32696.1 - 2.5e-18 66.1 0.0 1.3e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain HxlR PF01638.17 EON32698.1 - 1.4e-20 72.9 0.0 2.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MDMPI_C PF07398.11 EON32698.1 - 0.017 16.0 6.0 0.022 15.6 1.6 2.3 2 0 0 2 2 2 0 MDMPI C-terminal domain PadR PF03551.14 EON32698.1 - 0.05 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 EON32698.1 - 0.082 13.0 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SCP2 PF02036.17 EON32698.1 - 0.097 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family MFS_1 PF07690.16 EON32699.1 - 8.5e-43 146.6 46.8 1.6e-40 139.1 45.7 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON32699.1 - 0.0041 16.0 8.9 0.0041 16.0 8.9 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EON32699.1 - 2.8 6.1 10.7 0.22 9.8 0.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GntR PF00392.21 EON32700.1 - 1.5e-17 62.9 0.7 3.5e-17 61.8 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EON32700.1 - 3.2e-09 37.3 1.6 5.1e-09 36.6 1.6 1.3 1 0 0 1 1 1 1 FCD domain Rrf2 PF02082.20 EON32700.1 - 0.00044 20.5 0.0 0.00096 19.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 EON32700.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_41 PF14502.6 EON32700.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EON32700.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain ADP_ribosyl_GH PF03747.14 EON32701.1 - 4e-67 227.0 15.2 5.4e-67 226.6 15.2 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF222 PF02720.17 EON32702.1 - 1.9e-27 96.6 15.3 2.3e-27 96.3 15.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON32702.1 - 4.2e-09 36.4 9.6 6.9e-09 35.7 9.6 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON32702.1 - 0.038 13.8 4.1 0.069 13.0 4.1 1.3 1 0 0 1 1 1 0 HNH endonuclease PHD_2 PF13831.6 EON32702.1 - 1.3 8.6 9.4 0.046 13.3 2.4 2.1 2 0 0 2 2 2 0 PHD-finger TrpP PF17099.5 EON32703.1 - 0.036 13.8 7.2 1.3 8.7 5.2 2.5 2 0 0 2 2 2 0 Tryptophan transporter TrpP RseC_MucC PF04246.12 EON32703.1 - 1.2 9.1 12.9 0.63 10.0 3.1 2.6 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC FMN_red PF03358.15 EON32704.1 - 1.6e-19 70.1 0.1 1.9e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON32704.1 - 1.4e-06 28.1 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Amidohydro_1 PF01979.20 EON32705.1 - 1.1e-35 123.6 0.0 2.2e-35 122.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON32705.1 - 7.9e-16 58.6 1.1 1.9e-09 37.5 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Acetyltransf_6 PF13480.7 EON32705.1 - 0.029 14.5 0.5 0.14 12.3 0.2 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Putative_PNPOx PF01243.20 EON32706.1 - 1.1e-19 70.4 0.0 1.6e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EON32706.1 - 1.4e-05 25.1 0.4 2.8e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EON32706.1 - 4.8e-05 23.9 0.0 8.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EON32706.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like DUF4232 PF14016.6 EON32706.1 - 0.085 13.0 0.6 0.17 12.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Creatininase PF02633.14 EON32707.1 - 1.6e-66 224.2 0.5 1.9e-66 224.0 0.5 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase FAD_binding_4 PF01565.23 EON32708.1 - 5.9e-26 90.9 2.0 1.1e-25 90.0 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain TPP_enzyme_M PF00205.22 EON32708.1 - 0.057 13.1 0.0 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CgtA PF06306.11 EON32709.1 - 0.072 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) NMT1 PF09084.11 EON32709.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 NMT1/THI5 like BPD_transp_1 PF00528.22 EON32710.1 - 3.6e-18 66.0 13.6 8.4e-17 61.5 12.5 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Diphtheria_T PF02764.14 EON32710.1 - 0.011 15.7 0.2 0.024 14.6 0.2 1.5 1 0 0 1 1 1 0 Diphtheria toxin, T domain DUF2070 PF09843.9 EON32710.1 - 1.3 7.2 5.9 2.2 6.5 5.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) T2SSM PF04612.12 EON32710.1 - 1.6 8.7 4.5 1.1 9.2 0.3 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M PHO4 PF01384.20 EON32710.1 - 4.9 6.1 11.6 0.76 8.8 0.6 2.3 2 1 0 2 2 2 0 Phosphate transporter family ABC_tran PF00005.27 EON32711.1 - 3.5e-27 95.6 0.0 5.3e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EON32711.1 - 3.7e-06 27.4 0.0 5.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EON32711.1 - 0.0017 17.8 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON32711.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EON32711.1 - 0.0066 16.3 0.4 0.3 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON32711.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON32711.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EON32711.1 - 0.023 14.3 0.3 0.076 12.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EON32711.1 - 0.045 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 EON32711.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EON32711.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EON32711.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Amidohydro_3 PF07969.11 EON32712.1 - 3.7e-24 86.0 14.0 4e-21 76.0 9.7 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EON32712.1 - 1.6e-08 34.2 0.1 2.4e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family HTH_3 PF01381.22 EON32713.1 - 2.7e-14 53.0 0.1 4.4e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON32713.1 - 1.1e-13 51.3 1.8 1.1e-13 51.3 1.8 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Cupin_2 PF07883.11 EON32713.1 - 2e-12 46.6 0.3 7.8e-12 44.7 0.1 1.9 1 1 1 2 2 2 1 Cupin domain HTH_26 PF13443.6 EON32713.1 - 4.9e-07 30.1 0.0 7.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Cupin_3 PF05899.12 EON32713.1 - 2.8e-06 26.9 0.0 8.8e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) HTH_37 PF13744.6 EON32713.1 - 6.3e-05 22.9 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EON32713.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EON32713.1 - 0.0043 16.9 2.3 0.0047 16.7 0.1 2.3 3 1 1 4 4 4 1 Helix-turn-helix domain HTH_35 PF13693.6 EON32713.1 - 0.0046 16.9 0.1 0.0074 16.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TetR_N PF00440.23 EON32713.1 - 0.052 13.4 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Pirin_C_2 PF17954.1 EON32713.1 - 0.12 12.5 0.1 0.8 9.9 0.1 2.0 1 1 1 2 2 2 0 Quercetinase C-terminal cupin domain Fer2 PF00111.27 EON32714.1 - 3.9e-11 42.7 1.0 7.1e-11 41.9 1.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON32714.1 - 5e-06 27.1 0.0 0.00011 22.8 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON32714.1 - 0.00098 19.3 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EON32714.1 - 0.0057 17.0 0.0 0.0097 16.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.6 EON32714.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Amidohydro_1 PF01979.20 EON32715.1 - 1.1e-30 107.1 0.0 1.4e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON32715.1 - 3.4e-15 56.5 12.8 4.8e-11 42.8 6.8 2.1 1 1 0 2 2 2 2 Amidohydrolase family DUF1445 PF07286.12 EON32715.1 - 0.15 12.0 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) PIG-L PF02585.17 EON32716.1 - 1.4e-18 67.8 0.8 3.6e-18 66.4 0.8 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase HSP90 PF00183.18 EON32717.1 - 1.6e-137 459.6 0.0 7.1e-136 454.1 0.0 2.0 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EON32717.1 - 2e-11 43.9 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EON32717.1 - 1.7e-07 31.7 0.0 3.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F420H2_quin_red PF04075.14 EON32719.1 - 3.1e-23 82.3 0.0 3.6e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase BcrAD_BadFG PF01869.20 EON32720.1 - 1e-19 71.1 0.5 1.5e-19 70.5 0.5 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ECH_1 PF00378.20 EON32721.1 - 1.2e-47 162.4 0.0 1.9e-47 161.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON32721.1 - 7.9e-24 84.8 0.1 1.7e-21 77.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase 4HBT PF03061.22 EON32722.1 - 2.7e-06 27.6 0.6 4.6e-06 26.9 0.6 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RibD_C PF01872.17 EON32723.1 - 4.6e-13 49.4 0.0 1.5e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 RibD C-terminal domain HTH_18 PF12833.7 EON32724.1 - 5.9e-16 58.5 0.8 5.9e-16 58.5 0.8 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON32724.1 - 4.7e-08 32.9 0.0 0.0003 20.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DinB_2 PF12867.7 EON32724.1 - 1.4e-06 28.8 1.6 1.4e-06 28.8 1.6 2.0 2 0 0 2 2 2 1 DinB superfamily Rnk_N PF14760.6 EON32724.1 - 1.2 9.7 4.2 1.7 9.2 1.5 2.4 2 0 0 2 2 2 0 Rnk N-terminus Abhydrolase_9 PF10081.9 EON32725.1 - 5.1e-125 416.3 0.3 6.6e-125 415.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Abhydrolase_9_N PF15420.6 EON32725.1 - 1.8e-68 230.7 14.9 1.8e-68 230.7 14.9 1.6 2 0 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus DUF202 PF02656.15 EON32725.1 - 6.7 7.2 12.5 6.4 7.3 1.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ABC2_membrane_2 PF12679.7 EON32726.1 - 2.4e-05 23.7 17.7 0.00015 21.2 17.8 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EON32726.1 - 0.0003 20.8 6.1 0.00046 20.2 6.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 EON32726.1 - 0.51 9.9 7.4 3.5 7.1 7.5 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein SseC PF04888.12 EON32726.1 - 9.7 5.7 7.0 0.35 10.4 1.0 1.6 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ABC_tran PF00005.27 EON32727.1 - 6.3e-25 88.3 0.0 1.2e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32727.1 - 4.8e-13 49.6 0.1 3.3e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON32727.1 - 0.0088 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON32727.1 - 0.012 16.2 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EON32727.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 EON32727.1 - 0.17 11.7 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 MukB N-terminal HisKA_3 PF07730.13 EON32728.1 - 8.2e-18 64.7 3.7 2.9e-17 62.9 3.7 1.9 1 0 0 1 1 1 1 Histidine kinase Sensor_TM1 PF13755.6 EON32728.1 - 0.0068 16.1 0.5 0.018 14.8 0.5 1.7 1 0 0 1 1 1 1 Sensor N-terminal transmembrane domain ATP_bind_2 PF03668.15 EON32728.1 - 0.055 12.8 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family YhhN PF07947.14 EON32728.1 - 0.54 9.8 6.1 1.6 8.3 6.0 2.0 1 1 0 1 1 1 0 YhhN family Bax1-I PF01027.20 EON32728.1 - 0.59 9.9 6.2 1.8 8.4 6.3 1.6 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Response_reg PF00072.24 EON32729.1 - 4.7e-28 97.6 0.0 7.3e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON32729.1 - 2.8e-16 58.8 0.2 4.8e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON32729.1 - 7.8e-05 22.3 0.2 0.00018 21.1 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 EON32729.1 - 0.00026 20.5 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EON32729.1 - 0.0029 17.1 0.1 0.0077 15.7 0.1 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON32729.1 - 0.0046 16.9 0.1 0.0067 16.3 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r3 PF04539.16 EON32729.1 - 0.03 14.4 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_23 PF13384.6 EON32729.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain DapB_N PF01113.20 EON32730.1 - 2.2e-05 24.5 0.1 3.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EON32730.1 - 0.00024 21.5 0.0 0.0005 20.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EON32730.1 - 0.00031 20.7 0.2 0.00051 20.0 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EON32730.1 - 0.086 13.4 0.0 0.21 12.2 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 EON32730.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EON32730.1 - 0.14 13.0 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 EON32731.1 - 4.3e-64 216.3 0.5 5.3e-64 216.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON32731.1 - 1e-60 204.6 0.1 1.2e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON32731.1 - 1.6e-12 47.7 0.4 2.9e-12 46.9 0.4 1.4 1 0 0 1 1 1 1 KR domain SBF PF01758.16 EON32732.1 - 8.5e-15 54.9 9.0 8.5e-15 54.9 9.0 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 EON32732.1 - 1.3e-11 44.4 21.0 1.7e-11 44.0 21.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) CPBP PF02517.16 EON32733.1 - 1.1e-16 61.0 6.2 1.1e-16 61.0 6.2 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Auxin_canalis PF05703.11 EON32733.1 - 0.9 9.4 5.8 1.6 8.6 5.8 1.3 1 0 0 1 1 1 0 Auxin canalisation COX6C PF02937.15 EON32733.1 - 1.8 8.7 0.0 1.8 8.7 0.0 2.9 3 1 1 4 4 4 0 Cytochrome c oxidase subunit VIc UPRTase PF14681.6 EON32734.1 - 3.4e-69 232.4 0.0 3.9e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EON32734.1 - 1e-10 41.3 0.2 2e-10 40.4 0.2 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF1688 PF07958.11 EON32735.1 - 2.4e-141 471.3 0.0 2.7e-141 471.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GTP_CH_N PF12471.8 EON32736.1 - 3.1e-78 262.0 0.0 4.2e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EON32736.1 - 3e-15 56.2 0.0 4.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II peroxidase PF00141.23 EON32737.1 - 7.7e-81 271.1 0.0 3.1e-44 151.4 0.0 2.3 2 0 0 2 2 2 2 Peroxidase FUR PF01475.19 EON32738.1 - 1.1e-20 74.0 0.0 1.3e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 EON32738.1 - 0.0037 17.1 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 EON32738.1 - 0.0054 17.1 0.0 0.0071 16.7 0.0 1.1 1 0 0 1 1 1 1 Penicillinase repressor HTH_20 PF12840.7 EON32738.1 - 0.015 15.4 0.1 0.036 14.1 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain E2F_TDP PF02319.20 EON32738.1 - 0.066 13.3 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 EON32738.1 - 0.094 13.0 0.6 1.5 9.1 0.1 2.2 1 1 1 2 2 2 0 Transposase DUF3731 PF12531.8 EON32739.1 - 0.0067 16.3 3.5 0.011 15.6 3.5 1.2 1 0 0 1 1 1 1 DNA-K related protein YscO PF07321.12 EON32739.1 - 0.011 15.7 8.2 0.011 15.7 8.2 2.7 2 1 0 2 2 2 0 Type III secretion protein YscO PEARLI-4 PF05278.12 EON32739.1 - 0.066 12.8 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pes-10 PF07149.11 EON32739.1 - 0.095 11.8 1.1 0.13 11.3 0.5 1.5 2 0 0 2 2 2 0 Pes-10 ABC_tran_CTD PF16326.5 EON32739.1 - 1.1 9.6 8.4 1.2 9.5 1.0 3.5 3 1 1 4 4 4 0 ABC transporter C-terminal domain ATG16 PF08614.11 EON32739.1 - 2.2 8.5 16.5 0.16 12.2 4.6 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 EON32739.1 - 2.8 7.7 16.7 0.5 10.1 9.8 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF3391 PF11871.8 EON32739.1 - 3 8.4 9.6 0.33 11.5 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2203 PF09969.9 EON32739.1 - 8.6 7.1 8.7 1 10.1 0.7 2.8 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 EON32739.1 - 9.5 6.8 9.8 2.3 8.7 4.9 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region GXWXG PF14231.6 EON32740.1 - 1.1e-25 89.5 0.8 1.8e-25 88.8 0.8 1.4 1 0 0 1 1 1 1 GXWXG protein DUF4334 PF14232.6 EON32740.1 - 1.4e-25 89.0 0.4 2.5e-25 88.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) Putative_PNPOx PF01243.20 EON32741.1 - 2.2e-13 50.2 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON32741.1 - 2.1e-05 24.6 0.1 2.6e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EON32741.1 - 0.0029 17.2 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Glyoxalase_6 PF18029.1 EON32742.1 - 4.2e-27 95.0 2.4 9.5e-27 93.9 2.4 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain PhoD PF09423.10 EON32743.1 - 6.3e-15 55.0 4.1 6.2e-14 51.8 4.1 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase ABM PF03992.16 EON32745.1 - 4.1e-07 30.0 0.0 5.9e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase tify PF06200.14 EON32745.1 - 0.13 11.6 0.0 0.82 9.0 0.0 1.9 2 0 0 2 2 2 0 tify domain DNA_alkylation PF08713.11 EON32746.1 - 3.2e-19 69.5 0.0 3.6e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF2383 PF09537.10 EON32746.1 - 0.17 12.2 0.0 28 5.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) ELFV_dehydrog PF00208.21 EON32747.1 - 4.8e-69 232.8 1.8 6.7e-69 232.3 1.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EON32747.1 - 1.7e-48 163.7 0.0 4.1e-48 162.5 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 EON32747.1 - 0.0084 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Esterase PF00756.20 EON32749.1 - 3.9e-36 125.0 0.0 5.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EON32749.1 - 0.0028 17.5 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EON32749.1 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aldedh PF00171.22 EON32750.1 - 5.1e-136 453.8 0.2 6.7e-136 453.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lactamase_B PF00753.27 EON32751.1 - 1.9e-25 90.0 10.2 2.7e-25 89.6 10.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON32751.1 - 0.0001 21.9 2.4 0.00018 21.1 2.4 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Hepar_II_III PF07940.13 EON32751.1 - 0.00063 19.4 1.3 0.0011 18.7 1.0 1.3 1 1 0 1 1 1 1 Heparinase II/III-like protein HxlR PF01638.17 EON32753.1 - 4.1e-19 68.2 0.0 5.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 EON32753.1 - 0.00078 19.6 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_27 PF13463.6 EON32753.1 - 0.014 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 EON32753.1 - 0.018 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation HTH_24 PF13412.6 EON32753.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EON32753.1 - 0.052 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PadR PF03551.14 EON32753.1 - 0.062 13.3 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Thiolase_N PF00108.23 EON32754.1 - 4.1e-59 200.1 0.0 6.5e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON32754.1 - 8.9e-41 138.4 0.1 1.6e-40 137.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON32754.1 - 0.001 18.7 1.1 0.0027 17.3 1.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EON32754.1 - 0.035 14.0 0.8 1.6 8.6 0.3 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2802 PF10975.8 EON32754.1 - 0.29 11.3 2.0 0.58 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) LtrA PF06772.11 EON32755.1 - 2.2e-80 270.5 39.5 2.6e-80 270.3 39.5 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) TMEM174 PF15029.6 EON32755.1 - 0.09 12.5 0.7 0.16 11.7 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 AA_permease_2 PF13520.6 EON32756.1 - 2.4e-25 89.3 45.1 2.9e-25 89.0 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON32756.1 - 3.4e-23 82.0 37.7 4.7e-23 81.5 37.7 1.2 1 0 0 1 1 1 1 Amino acid permease CcmH PF03918.14 EON32756.1 - 0.18 11.1 0.3 14 4.9 0.1 2.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Bac_luciferase PF00296.20 EON32757.1 - 5.5e-55 187.0 7.0 1.1e-54 186.0 7.0 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase TraD PF06412.11 EON32757.1 - 0.057 13.2 0.2 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Conjugal transfer protein TraD Bac_luciferase PF00296.20 EON32758.1 - 1.4e-06 28.0 1.5 2.5e-06 27.2 1.5 1.4 1 0 0 1 1 1 1 Luciferase-like monooxygenase Acyl-CoA_dh_M PF02770.19 EON32759.1 - 1.8e-09 37.6 0.1 4.1e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32759.1 - 2.3e-09 37.6 8.2 2.3e-09 37.6 8.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32759.1 - 0.0017 19.0 0.9 0.0046 17.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acetyltransf_9 PF13527.7 EON32760.1 - 4.7e-20 72.0 0.0 1.3e-19 70.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 EON32760.1 - 2e-19 70.5 0.6 5.9e-19 69.0 0.5 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 EON32760.1 - 1.1e-14 54.6 0.0 2.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_1 PF00583.25 EON32760.1 - 3.5e-05 24.0 0.0 6.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON32760.1 - 0.00039 20.8 0.1 0.00095 19.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON32760.1 - 0.048 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 FR47-like protein SBP_bac_5 PF00496.22 EON32761.1 - 2.3e-74 250.6 0.1 3e-74 250.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EON32762.1 - 2.7e-43 147.9 7.7 2.7e-43 147.9 7.7 2.5 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EON32763.1 - 7.1e-22 78.0 13.1 7.1e-22 78.0 13.1 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EON32763.1 - 0.0031 17.5 0.1 0.0031 17.5 0.1 3.0 3 1 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C RskA PF10099.9 EON32763.1 - 3.7 7.8 13.4 1.4e+03 -0.6 12.6 2.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ABC_tran PF00005.27 EON32764.1 - 3.4e-55 186.3 0.0 1.4e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON32764.1 - 4.4e-16 59.6 2.9 0.0006 19.7 0.0 4.1 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON32764.1 - 3.7e-08 33.7 0.4 0.0093 16.2 0.3 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EON32764.1 - 1.3e-07 31.2 0.4 0.0057 16.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EON32764.1 - 2.3e-07 30.4 0.0 0.0027 17.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI oligo_HPY PF08352.12 EON32764.1 - 1.3e-06 28.8 0.2 3.8e-06 27.3 0.1 1.8 2 0 0 2 2 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EON32764.1 - 2e-06 27.4 0.0 0.037 13.5 0.0 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON32764.1 - 2.3e-06 28.1 7.0 0.0026 18.2 3.0 2.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EON32764.1 - 8.6e-05 22.6 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EON32764.1 - 8.6e-05 22.5 0.0 0.089 12.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 EON32764.1 - 0.00021 21.2 0.2 0.56 10.1 0.1 2.6 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.17 EON32764.1 - 0.00024 21.3 0.2 0.62 10.1 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA PF00004.29 EON32764.1 - 0.00029 21.3 0.1 0.78 10.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EON32764.1 - 0.002 18.3 0.1 0.94 9.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 EON32764.1 - 0.0022 17.7 0.1 1.8 8.3 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EON32764.1 - 0.0025 17.4 5.2 0.6 9.7 0.1 4.3 4 2 0 4 4 4 1 AAA domain APS_kinase PF01583.20 EON32764.1 - 0.0049 16.8 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.6 EON32764.1 - 0.0066 17.0 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EON32764.1 - 0.0067 16.2 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EON32764.1 - 0.011 15.8 0.4 0.87 9.7 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EON32764.1 - 0.013 15.2 0.4 8.9 6.0 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.22 EON32764.1 - 0.022 14.0 0.4 4.5 6.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 EON32764.1 - 0.025 14.3 0.1 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EON32764.1 - 0.026 14.9 0.2 7.2 7.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 EON32764.1 - 0.031 14.0 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EON32764.1 - 0.032 14.8 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON32764.1 - 0.035 13.8 0.3 7.3 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EON32764.1 - 0.061 12.8 0.0 4 6.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 EON32764.1 - 0.069 13.4 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EON32764.1 - 0.076 12.3 0.1 9.2 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 EON32764.1 - 0.084 12.2 0.1 11 5.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 EON32764.1 - 0.11 12.8 0.3 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EON32764.1 - 0.15 12.2 1.0 17 5.4 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DLIC PF05783.11 EON32764.1 - 0.24 10.2 0.1 2 7.1 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) SbcCD_C PF13558.6 EON32764.1 - 0.29 11.4 0.9 1.7 8.9 0.2 2.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMPL PF03176.15 EON32765.1 - 7.4e-115 383.4 31.1 1.3e-64 218.3 6.7 2.1 2 0 0 2 2 2 2 MMPL family FeS_assembly_P PF01883.19 EON32765.1 - 0.018 15.2 0.7 0.43 10.8 0.1 2.7 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein HTH_27 PF13463.6 EON32766.1 - 6.7e-14 52.1 0.1 1.3e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 EON32766.1 - 1.6e-11 43.9 0.1 3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON32766.1 - 2.2e-10 40.3 0.3 5.8e-10 38.9 0.3 1.8 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EON32766.1 - 6.1e-08 32.4 0.1 2.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EON32766.1 - 4.6e-06 26.1 0.0 9.2e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EON32766.1 - 7.4e-05 22.6 0.1 0.00016 21.6 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 EON32766.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 EON32766.1 - 0.00029 21.0 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 EON32766.1 - 0.0015 18.3 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_11 PF08279.12 EON32766.1 - 0.0016 18.4 0.1 0.0033 17.4 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_36 PF13730.6 EON32766.1 - 0.0023 17.9 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 EON32766.1 - 0.0031 17.5 0.2 0.0092 16.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 EON32766.1 - 0.0059 16.4 1.1 0.049 13.4 0.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain DUF4423 PF14394.6 EON32766.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) LexA_DNA_bind PF01726.16 EON32766.1 - 0.029 14.1 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain FtsK_gamma PF09397.10 EON32766.1 - 0.032 14.0 0.2 0.11 12.3 0.1 1.8 1 1 1 2 2 2 0 Ftsk gamma domain Replic_Relax PF13814.6 EON32766.1 - 0.033 14.3 0.3 0.044 13.9 0.3 1.2 1 0 0 1 1 1 0 Replication-relaxation Rrf2 PF02082.20 EON32766.1 - 0.039 14.3 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator LacI PF00356.21 EON32766.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_5 PF01022.20 EON32766.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RepL PF05732.11 EON32766.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Acetyltransf_10 PF13673.7 EON32768.1 - 1.4e-16 60.6 0.0 1.7e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON32768.1 - 8.9e-13 48.5 0.1 1.4e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON32768.1 - 4e-11 43.2 0.1 5.6e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 EON32768.1 - 6.4e-06 26.4 1.9 1.2e-05 25.5 1.9 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 EON32768.1 - 0.0066 16.3 0.0 0.0094 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON32768.1 - 0.0095 16.6 0.0 0.014 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON32768.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EON32768.1 - 0.038 14.1 0.0 0.93 9.6 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EON32768.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ AAA_33 PF13671.6 EON32769.1 - 4.5e-14 52.8 0.0 6.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON32769.1 - 6.7e-07 29.9 0.0 1.3e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain MDMPI_N PF11716.8 EON32769.1 - 0.0047 17.6 1.5 0.0047 17.6 1.5 2.3 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain AAA_22 PF13401.6 EON32769.1 - 0.011 16.0 0.0 0.48 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain DinB PF05163.12 EON32769.1 - 0.022 14.7 0.1 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 DinB family NOZZLE PF08744.10 EON32770.1 - 0.063 12.8 0.6 0.1 12.1 0.6 1.4 1 0 0 1 1 1 0 Plant transcription factor NOZZLE PE-PPE PF08237.11 EON32771.1 - 1.3e-10 41.2 0.2 4e-10 39.6 0.2 1.7 1 1 0 1 1 1 1 PE-PPE domain Cutinase PF01083.22 EON32771.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase AHSA1 PF08327.11 EON32773.1 - 7.1e-22 78.0 0.4 8.1e-22 77.8 0.4 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DoxX PF07681.12 EON32774.1 - 5.9e-11 42.8 5.9 5.9e-11 42.8 5.9 1.7 2 0 0 2 2 2 1 DoxX Phage_holin_3_6 PF07332.11 EON32774.1 - 0.34 11.0 6.0 0.23 11.5 3.0 1.9 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DctQ PF04290.12 EON32774.1 - 2.1 8.2 9.3 0.34 10.8 4.4 2.0 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1801 PF08818.11 EON32775.1 - 3.8e-08 33.7 0.0 4.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) LysE PF01810.18 EON32776.1 - 0.015 14.8 5.5 0.046 13.2 5.2 1.8 1 1 0 1 1 1 0 LysE type translocator Polyketide_cyc2 PF10604.9 EON32779.1 - 1.2e-07 32.1 2.8 1.3e-07 32.0 2.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4436 PF14494.6 EON32780.1 - 4.3e-71 239.2 0.3 5e-71 239.0 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) 2TM PF13239.6 EON32780.1 - 0.19 12.0 0.9 0.34 11.3 0.9 1.3 1 0 0 1 1 1 0 2TM domain adh_short PF00106.25 EON32781.1 - 1.4e-29 103.0 2.1 1e-28 100.1 2.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32781.1 - 5.5e-18 65.4 2.5 2.1e-17 63.5 2.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32781.1 - 8.5e-09 35.6 1.1 1.5e-08 34.7 1.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32781.1 - 0.0057 16.1 0.2 0.0099 15.4 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EON32781.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EON32781.1 - 0.05 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 EON32781.1 - 0.071 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 EON32781.1 - 0.14 11.3 0.1 0.24 10.5 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TetR_C_21 PF17926.1 EON32782.1 - 1.8e-23 82.8 1.6 2.8e-23 82.2 1.6 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON32782.1 - 4.2e-12 45.7 1.4 7.9e-12 44.8 1.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MerR_1 PF13411.6 EON32783.1 - 5.5e-13 48.8 0.0 8.8e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EON32783.1 - 1.9e-08 33.9 0.0 4.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EON32783.1 - 3.5e-07 30.7 1.2 5.3e-07 30.1 1.2 1.3 1 0 0 1 1 1 1 MerR, DNA binding GyrI-like PF06445.15 EON32783.1 - 5.1e-06 26.9 0.0 7.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 GyrI-like small molecule binding domain SnoaL_2 PF12680.7 EON32784.1 - 5.8e-05 23.7 3.7 0.00013 22.5 3.7 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EON32784.1 - 0.0013 18.9 1.7 0.0015 18.6 1.7 1.3 1 1 0 1 1 1 1 SnoaL-like domain adh_short PF00106.25 EON32785.1 - 8.2e-18 64.6 0.0 1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32785.1 - 1.7e-14 53.9 0.0 1.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32785.1 - 2.2e-09 37.5 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON32785.1 - 0.00077 19.4 0.1 0.00093 19.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EON32785.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3742 PF12553.8 EON32786.1 - 0.0059 16.7 1.0 0.013 15.6 0.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3742) AHSA1 PF08327.11 EON32787.1 - 0.062 13.5 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein HTH_18 PF12833.7 EON32788.1 - 2.2e-17 63.1 0.5 4.2e-17 62.2 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON32788.1 - 4.7e-13 48.9 0.1 1.1e-12 47.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding_2 PF14525.6 EON32788.1 - 3.2e-12 46.5 4.6 5.4e-12 45.7 4.6 1.3 1 0 0 1 1 1 1 AraC-binding-like domain HTH_18 PF12833.7 EON32789.1 - 1.7e-18 66.7 1.5 3.3e-18 65.7 0.7 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON32789.1 - 1.5e-08 34.5 0.0 7.9e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family Amidase PF01425.21 EON32790.1 - 3.8e-54 184.3 4.4 2.4e-48 165.2 5.6 2.1 2 0 0 2 2 2 2 Amidase DUF5058 PF16481.5 EON32792.1 - 0.02 14.6 0.3 0.027 14.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Como_LCP PF02247.16 EON32792.1 - 0.047 12.3 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Large coat protein ADH_zinc_N_2 PF13602.6 EON32793.1 - 6.3e-20 72.6 0.1 1.4e-19 71.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EON32793.1 - 4.8e-18 65.4 0.1 8.2e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON32793.1 - 2.2e-08 33.9 0.5 7.7e-08 32.2 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PGM_PMM_II PF02879.16 EON32793.1 - 0.0047 17.5 0.0 0.23 12.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ADH_N_2 PF16884.5 EON32793.1 - 0.038 13.9 0.4 0.25 11.2 0.2 2.4 3 1 0 3 3 3 0 N-terminal domain of oxidoreductase DUF1761 PF08570.10 EON32795.1 - 1.7e-05 25.1 10.9 3.5e-05 24.1 10.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1761) TetR_N PF00440.23 EON32796.1 - 7.5e-07 28.9 0.0 4e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 EON32796.1 - 0.042 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_IclR PF09339.10 EON32796.1 - 0.043 13.6 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain ABC_membrane PF00664.23 EON32797.1 - 7.6e-34 117.6 2.0 1e-33 117.2 2.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EON32797.1 - 3.3e-31 108.6 0.0 5.4e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON32797.1 - 5.5e-08 32.5 0.0 5.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON32797.1 - 0.00042 20.0 0.0 0.009 15.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EON32797.1 - 0.00044 20.2 0.4 0.23 11.2 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON32797.1 - 0.0011 19.5 0.2 0.0019 18.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain EI24 PF07264.11 EON32797.1 - 0.0012 19.1 8.1 0.14 12.4 2.0 2.2 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) AAA_22 PF13401.6 EON32797.1 - 0.0025 18.1 0.0 0.0062 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON32797.1 - 0.0037 17.7 0.0 0.0077 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EON32797.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Methyltransf_11 PF08241.12 EON32799.1 - 4.2e-19 69.0 0.0 7.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32799.1 - 1.1e-17 64.5 0.1 1.8e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON32799.1 - 7.4e-15 54.9 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EON32799.1 - 1.4e-13 50.9 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32799.1 - 5.8e-08 32.7 0.0 7.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32799.1 - 0.00035 21.2 0.0 0.0006 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EON32799.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 EON32799.1 - 0.0046 16.7 0.0 0.0087 15.8 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EON32799.1 - 0.023 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein RcpC PF16976.5 EON32799.1 - 0.032 14.3 0.7 0.092 12.8 0.2 2.0 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB PrmA PF06325.13 EON32799.1 - 0.058 12.8 0.2 0.079 12.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EON32799.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GerE PF00196.19 EON32800.1 - 7.8e-14 51.0 0.3 1.7e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 EON32800.1 - 2e-11 44.6 6.5 4e-05 24.1 0.2 3.6 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EON32800.1 - 0.00032 21.0 0.0 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma70_r4_2 PF08281.12 EON32800.1 - 0.0036 17.0 0.1 0.021 14.5 0.1 2.4 1 0 0 1 1 1 1 Sigma-70, region 4 TPR_12 PF13424.6 EON32800.1 - 0.011 16.0 17.3 0.034 14.4 2.8 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat HTH_38 PF13936.6 EON32800.1 - 0.02 14.6 1.1 0.12 12.1 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EON32800.1 - 0.023 14.5 4.5 0.14 12.0 0.1 3.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.6 EON32800.1 - 0.038 13.5 0.1 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EON32800.1 - 0.057 13.5 3.6 0.12 12.4 0.2 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain AAA PF00004.29 EON32800.1 - 0.068 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EON32800.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNAP PF14938.6 EON32800.1 - 7.1 6.0 7.0 5.8 6.2 4.9 1.8 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP RsgA_GTPase PF03193.16 EON32801.1 - 4e-39 134.2 0.2 5.1e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EON32801.1 - 4.3e-07 30.0 0.0 9.8e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EON32801.1 - 0.00014 21.3 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EON32801.1 - 0.00019 21.5 1.5 0.0099 15.9 0.3 2.4 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 EON32801.1 - 0.00029 21.4 0.0 0.00045 20.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 EON32801.1 - 0.0022 17.5 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Hpr_kinase_C PF07475.12 EON32801.1 - 0.039 13.5 0.5 0.096 12.2 0.5 1.7 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EON32801.1 - 0.05 14.0 1.8 0.075 13.4 0.5 1.9 2 1 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 EON32801.1 - 0.052 13.1 4.3 0.17 11.4 0.3 2.5 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EON32801.1 - 0.15 11.8 1.0 0.31 10.8 1.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 EON32801.1 - 0.15 11.1 0.2 0.27 10.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 EON32801.1 - 0.17 11.6 1.0 7.6 6.3 0.0 2.9 2 1 2 4 4 4 0 Ethanolamine utilisation - propanediol utilisation NfeD PF01957.18 EON32802.1 - 0.035 14.5 0.1 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding SOG2 PF10428.9 EON32802.1 - 0.094 11.9 6.8 0.11 11.7 6.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short PF00106.25 EON32803.1 - 4.7e-24 84.9 0.1 3.2e-23 82.2 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32803.1 - 2e-18 66.8 0.1 2.8e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32803.1 - 1.7e-06 28.1 0.3 2.9e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32803.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MLTR_LBD PF17765.1 EON32805.1 - 3.1e-38 131.5 0.1 4.3e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 EON32805.1 - 1.7e-08 34.6 1.9 3.8e-08 33.6 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 EON32805.1 - 0.077 13.1 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix DUF4229 PF14012.6 EON32806.1 - 0.72 10.0 3.8 0.28 11.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) zinc_ribbon_15 PF17032.5 EON32808.1 - 0.00014 22.6 0.0 0.00014 22.6 0.0 1.0 1 0 0 1 1 1 1 zinc-ribbon family Wza_C PF18412.1 EON32808.1 - 0.22 11.3 2.3 0.33 10.8 2.3 1.2 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain UPF0061 PF02696.14 EON32809.1 - 3.4e-116 388.8 0.0 4.2e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-dskA_traR PF01258.17 EON32810.1 - 1.4e-10 41.0 4.8 2.3e-10 40.2 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DinB_2 PF12867.7 EON32810.1 - 0.047 14.2 0.3 0.14 12.6 0.3 1.8 1 1 0 1 1 1 0 DinB superfamily ASD2 PF08687.11 EON32810.1 - 0.17 11.4 1.0 0.22 11.0 1.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 ADH_N PF08240.12 EON32811.1 - 5.2e-27 93.9 0.1 5.2e-27 93.9 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON32811.1 - 1.3e-20 73.7 0.4 2e-20 73.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON32811.1 - 2e-10 41.8 0.8 3.3e-10 41.1 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EON32811.1 - 0.06 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Acyltransferase PF01553.21 EON32812.1 - 1.5e-12 47.3 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Virul_fac_BrkB PF03631.15 EON32813.1 - 3.5e-69 233.3 21.8 4e-69 233.1 21.8 1.0 1 0 0 1 1 1 1 Virulence factor BrkB UPF0182 PF03699.13 EON32813.1 - 9.6 4.2 7.3 3.2 5.7 5.0 1.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) DUF1206 PF06724.11 EON32814.1 - 8.1e-46 154.0 50.4 7.4e-16 58.0 8.1 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF5134 PF17197.4 EON32814.1 - 0.8 9.6 12.1 2.8 7.8 10.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Isochorismatase PF00857.20 EON32815.1 - 4.1e-30 105.2 0.2 5.4e-30 104.8 0.2 1.2 1 0 0 1 1 1 1 Isochorismatase family HTH_18 PF12833.7 EON32816.1 - 4.6e-19 68.5 1.3 8.4e-19 67.6 1.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON32816.1 - 6.5e-12 45.2 0.0 8.2e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 EON32816.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family TetR_N PF00440.23 EON32816.1 - 0.12 12.1 0.3 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family DUF1622 PF07784.11 EON32817.1 - 2.5e-21 75.3 4.4 2.5e-21 75.3 4.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1622) FMO-like PF00743.19 EON32818.1 - 5.3e-12 44.9 0.0 5.4e-11 41.6 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON32818.1 - 6.4e-11 42.0 0.0 1.4e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON32818.1 - 4.2e-09 36.5 0.8 4.1e-07 30.1 0.1 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EON32818.1 - 2.8e-07 30.0 0.1 6.9e-06 25.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EON32818.1 - 6e-07 28.9 0.0 1.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EON32818.1 - 9.4e-07 28.7 9.8 3.9e-05 23.4 2.8 3.7 2 1 2 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON32818.1 - 3.8e-06 26.4 0.1 2.4e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EON32818.1 - 2.8e-05 22.9 0.0 0.035 12.7 0.0 2.5 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 EON32818.1 - 0.00013 22.5 0.2 0.05 14.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EON32818.1 - 0.00036 20.6 0.1 0.18 11.9 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EON32818.1 - 0.0041 17.1 3.9 1.2 9.1 0.3 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EON32818.1 - 0.0076 16.7 0.1 0.051 14.0 0.0 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding MCRA PF06100.11 EON32818.1 - 0.026 13.3 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 EON32818.1 - 0.033 13.3 0.5 0.19 10.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EON32818.1 - 0.16 11.0 1.6 6.1 5.8 0.1 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EON32818.1 - 0.18 11.1 0.5 0.48 9.7 0.5 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EON32818.1 - 0.21 10.4 0.7 7 5.4 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 EON32818.1 - 0.94 8.5 3.2 13 4.7 0.2 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 EON32819.1 - 1.2e-20 74.4 1.2 1.7e-20 73.9 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON32819.1 - 1.1e-07 31.9 1.3 2.9e-07 30.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EON32819.1 - 0.00019 20.8 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EON32819.1 - 0.00023 20.5 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON32819.1 - 0.00037 19.7 0.2 0.00047 19.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 EON32819.1 - 0.00099 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON32819.1 - 0.0025 17.8 0.1 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EON32819.1 - 0.027 13.8 0.2 0.042 13.1 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EON32819.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 EON32819.1 - 0.053 12.6 0.1 0.093 11.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 EON32819.1 - 0.09 12.4 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EON32819.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EON32819.1 - 0.11 13.0 0.2 0.22 12.1 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON32819.1 - 0.13 11.3 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Phos_pyr_kin PF08543.12 EON32820.1 - 2.8e-64 216.9 0.2 3.4e-64 216.6 0.2 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EON32820.1 - 6.2e-09 35.6 1.2 8.2e-09 35.2 1.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EON32820.1 - 0.13 11.6 2.6 0.21 11.0 2.6 1.4 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family ADH_N PF08240.12 EON32821.1 - 1.7e-28 98.6 2.5 5.1e-28 97.1 2.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON32821.1 - 5.8e-12 45.7 0.4 1.5e-08 34.7 0.2 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EON32821.1 - 4.5e-05 23.3 1.9 9e-05 22.3 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 EON32821.1 - 0.0015 17.9 0.2 0.0024 17.2 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EON32821.1 - 0.013 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ETF PF01012.21 EON32821.1 - 0.19 11.6 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain UDG PF03167.19 EON32823.1 - 1.1e-38 132.7 0.0 1.3e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SnoaL_4 PF13577.6 EON32824.1 - 2.4e-24 85.9 0.1 2.9e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EON32824.1 - 9.9e-06 26.1 1.0 1.6e-05 25.5 1.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain Scytalone_dh PF02982.14 EON32824.1 - 8.3e-05 22.4 0.1 0.00065 19.5 0.1 2.0 2 0 0 2 2 2 1 Scytalone dehydratase DUF4440 PF14534.6 EON32824.1 - 0.053 13.9 0.7 0.1 13.0 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL PF07366.12 EON32824.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Lumazine_bd_2 PF12893.7 EON32824.1 - 0.12 13.1 0.0 0.55 10.9 0.0 1.9 1 1 1 2 2 2 0 Putative lumazine-binding NAD_binding_10 PF13460.6 EON32825.1 - 1.9e-23 83.3 0.2 3.2e-23 82.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON32825.1 - 6.5e-20 71.7 0.0 7.9e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EON32825.1 - 6.9e-16 58.4 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON32825.1 - 4.8e-09 35.6 0.0 6.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EON32825.1 - 1.3e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EON32825.1 - 0.00057 19.4 0.0 0.00087 18.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EON32825.1 - 0.0011 18.2 0.1 0.0016 17.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain PAC2 PF09754.9 EON32825.1 - 0.037 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 PAC2 family DUF2867 PF11066.8 EON32825.1 - 0.069 13.5 0.1 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2867) TrkA_N PF02254.18 EON32825.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 EON32825.1 - 0.11 11.7 0.1 0.26 10.4 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein KR PF08659.10 EON32825.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EON32825.1 - 0.17 10.9 0.1 0.78 8.8 0.1 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Virul_fac_BrkB PF03631.15 EON32826.1 - 2.2e-34 119.3 17.6 2.7e-34 118.9 17.6 1.1 1 0 0 1 1 1 1 Virulence factor BrkB Multi_Drug_Res PF00893.19 EON32827.1 - 1.9e-17 63.7 5.7 2.4e-17 63.4 5.7 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EON32827.1 - 0.0086 16.2 10.3 0.041 14.1 10.3 1.9 1 1 0 1 1 1 1 EamA-like transporter family Caps_synth_CapC PF14102.6 EON32827.1 - 0.019 15.3 8.5 0.075 13.5 8.5 1.8 1 1 0 1 1 1 0 Capsule biosynthesis CapC TMEM234 PF10639.9 EON32827.1 - 0.049 13.7 0.5 0.055 13.5 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 EON32828.1 - 1.1e-14 54.9 10.6 1.1e-14 54.9 10.6 1.4 1 1 1 2 2 2 1 Small Multidrug Resistance protein EamA PF00892.20 EON32828.1 - 0.01 16.0 12.8 0.048 13.8 12.8 1.8 1 1 0 1 1 1 0 EamA-like transporter family DUF3098 PF11297.8 EON32828.1 - 0.12 12.0 0.3 0.12 12.0 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3098) DUF4233 PF14017.6 EON32828.1 - 0.16 12.3 12.3 0.37 11.1 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) DoxX PF07681.12 EON32829.1 - 8.1e-20 71.2 10.8 8.1e-20 71.2 10.8 1.8 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 EON32829.1 - 1.2e-05 25.2 4.6 4e-05 23.6 3.4 1.9 2 0 0 2 2 2 1 TQO small subunit DoxD DoxX_2 PF13564.6 EON32829.1 - 7.2e-05 22.8 13.0 0.00011 22.3 11.4 1.8 1 1 1 2 2 2 1 DoxX-like family MarR PF01047.22 EON32830.1 - 6.6e-10 38.8 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON32830.1 - 1.6e-07 31.1 0.1 5.6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 EON32830.1 - 0.00043 20.7 0.0 0.0011 19.4 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EON32830.1 - 0.039 13.7 0.1 0.077 12.8 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 EON32830.1 - 0.044 14.1 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 EON32830.1 - 0.046 13.3 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding AbiEi_4 PF13338.6 EON32830.1 - 0.13 12.5 0.6 0.32 11.2 0.2 2.1 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin MLTR_LBD PF17765.1 EON32831.1 - 5.2e-37 127.5 3.2 5.2e-37 127.5 3.2 1.8 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 EON32831.1 - 6.8e-15 55.2 3.6 6.8e-15 55.2 3.6 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 EON32831.1 - 6.1e-05 23.0 0.1 0.00025 21.0 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix GRIP PF01465.20 EON32831.1 - 0.16 11.9 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 0 GRIP domain adh_short PF00106.25 EON32832.1 - 6.3e-36 123.7 0.0 8.2e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON32832.1 - 2.2e-19 70.0 0.0 2.8e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON32832.1 - 7.5e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON32832.1 - 1.2e-06 28.2 0.0 3.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON32832.1 - 0.001 19.0 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON32832.1 - 0.068 12.6 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NMO PF03060.15 EON32833.1 - 5.1e-70 236.5 0.1 6.2e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.17 EON32833.1 - 0.00019 20.8 0.1 0.00042 19.7 0.1 1.6 1 1 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 EON32833.1 - 0.0021 17.6 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 EON32833.1 - 0.011 14.9 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NanE PF04131.14 EON32833.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 EON32833.1 - 0.12 11.4 0.3 2.5 7.0 0.3 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Sugar_tr PF00083.24 EON32834.1 - 8.9e-117 390.7 24.9 1.1e-116 390.5 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EON32834.1 - 1.9e-38 132.3 64.2 3e-36 125.1 39.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON32834.1 - 0.00034 19.6 1.2 0.00034 19.6 1.2 2.8 2 1 1 3 3 3 1 MFS_1 like family EAL PF00563.20 EON32835.1 - 2.3e-64 217.2 0.0 3.5e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EON32835.1 - 9.3e-35 119.8 0.0 2.1e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 EON32835.1 - 2.3e-27 95.2 0.4 3.7e-07 30.1 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 EON32835.1 - 3.6e-26 91.4 0.0 3.3e-08 33.7 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 EON32835.1 - 2.7e-24 85.5 11.4 5e-09 36.4 0.1 4.5 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 EON32835.1 - 3.4e-23 81.2 2.3 1.3e-06 28.3 0.0 4.2 4 0 0 4 4 4 3 PAS domain MLTR_LBD PF17765.1 EON32835.1 - 2.4e-05 24.5 3.3 0.019 15.1 0.2 3.8 4 0 0 4 4 4 2 MmyB-like transcription regulator ligand binding domain PAS_10 PF13596.6 EON32835.1 - 2.5e-05 24.8 0.0 0.0037 17.8 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 EON32835.1 - 0.00012 22.3 0.1 3.7 7.9 0.0 3.8 4 0 0 4 4 4 2 PAS fold PAS_7 PF12860.7 EON32835.1 - 0.0065 16.6 2.4 0.3 11.3 0.0 3.8 4 1 0 4 4 4 1 PAS fold DUF4135 PF13575.6 EON32835.1 - 0.18 11.1 0.4 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) GEMIN8 PF15348.6 EON32835.1 - 0.33 11.2 1.4 0.56 10.5 1.4 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SLATT_6 PF18169.1 EON32836.1 - 0.017 14.7 0.5 0.035 13.7 0.5 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Bac_luciferase PF00296.20 EON32837.1 - 2.2e-13 50.3 7.4 9.2e-09 35.2 0.5 2.3 1 1 1 2 2 2 2 Luciferase-like monooxygenase ABC2_membrane PF01061.24 EON32838.1 - 9.2e-05 21.9 30.7 0.00013 21.4 6.0 3.3 2 1 0 2 2 2 2 ABC-2 type transporter DUF3153 PF11353.8 EON32838.1 - 0.59 9.7 1.6 0.72 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) ABC2_membrane_3 PF12698.7 EON32838.1 - 0.6 9.2 25.5 0.15 11.2 3.9 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein PilX_N PF14341.6 EON32838.1 - 5.9 6.9 12.6 0.068 13.1 3.2 2.8 2 0 0 2 2 2 0 PilX N-terminal ABC_tran PF00005.27 EON32839.1 - 8.2e-25 87.9 0.0 1.3e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32839.1 - 1.7e-13 51.1 0.0 9.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EON32839.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON32839.1 - 0.0034 17.1 1.1 0.015 15.0 0.4 2.1 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 EON32839.1 - 0.004 17.7 0.0 0.0065 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EON32839.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EON32839.1 - 0.016 15.1 0.0 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_29 PF13555.6 EON32839.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLP1_P PF16575.5 EON32839.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EON32839.1 - 0.074 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 EON32839.1 - 0.094 12.3 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Hva1_TUDOR PF11160.8 EON32840.1 - 8.2e-19 67.5 0.8 9.7e-19 67.3 0.8 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain PadR PF03551.14 EON32841.1 - 8.5e-23 80.1 0.1 1.1e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EON32841.1 - 4e-05 23.7 0.0 6.2e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain Replic_Relax PF13814.6 EON32841.1 - 0.034 14.2 0.1 0.035 14.2 0.1 1.1 1 0 0 1 1 1 0 Replication-relaxation Oxidored_molyb PF00174.19 EON32843.1 - 3.4e-29 101.7 0.0 4.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.21 EON32844.1 - 1.9e-13 51.0 0.0 2.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON32844.1 - 2.4e-11 43.8 0.0 3.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EON32844.1 - 0.0033 17.5 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain GSHPx PF00255.19 EON32845.1 - 5.5e-43 144.9 0.0 6.7e-43 144.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EON32845.1 - 3.4e-07 30.2 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EON32845.1 - 0.0022 17.7 0.0 0.0092 15.7 0.0 1.8 2 0 0 2 2 2 1 Redoxin DUF1295 PF06966.12 EON32846.1 - 2.2e-39 135.4 9.2 3.1e-39 134.9 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EON32846.1 - 0.00028 21.2 0.5 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EON32846.1 - 0.003 17.6 0.2 0.0064 16.5 0.2 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EON32846.1 - 0.008 16.6 1.3 0.008 16.6 1.3 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase Pyr_redox_2 PF07992.14 EON32847.1 - 1e-19 70.9 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32847.1 - 0.00047 20.7 0.1 0.012 16.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON32847.1 - 0.0028 16.9 0.2 0.084 12.1 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON32847.1 - 0.016 15.4 0.1 0.071 13.3 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EON32847.1 - 0.037 13.2 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EON32847.1 - 0.051 13.6 3.1 1.5 8.8 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EON32847.1 - 0.089 11.8 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_oprn_chp PF09534.10 EON32848.1 - 0.13 12.0 7.0 0.02 14.7 2.1 1.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ceramidase PF05875.12 EON32848.1 - 0.15 11.5 0.5 0.2 11.0 0.5 1.2 1 0 0 1 1 1 0 Ceramidase DUF4381 PF14316.6 EON32848.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Asp4 PF16996.5 EON32848.1 - 0.49 10.2 4.5 6.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 DUF3021 PF11457.8 EON32848.1 - 4.2 7.7 10.3 8.2 6.8 6.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) ECH_1 PF00378.20 EON32849.1 - 1.9e-44 151.8 0.0 2.4e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON32849.1 - 6.4e-33 114.7 0.0 1.3e-30 107.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 EON32850.1 - 5.6e-105 351.4 0.3 6.7e-105 351.1 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON32850.1 - 2.6e-20 73.2 1.9 4.2e-20 72.5 0.3 2.3 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Sigma70_r2 PF04542.14 EON32851.1 - 0.00012 21.8 2.0 0.00012 21.7 0.1 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON32851.1 - 0.0099 15.5 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 TPR_2 PF07719.17 EON32851.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EON32851.1 - 0.015 15.0 0.2 0.044 13.5 0.2 1.8 1 0 0 1 1 1 0 TPR repeat HTH_10 PF04967.12 EON32851.1 - 0.032 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain TPR_7 PF13176.6 EON32851.1 - 0.15 12.1 2.4 0.27 11.4 1.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EON32851.1 - 0.19 12.1 0.9 0.87 10.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EON32851.1 - 0.59 10.5 8.6 0.25 11.7 1.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 EON32851.1 - 0.89 9.2 4.8 1.2 8.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain YCII PF03795.14 EON32852.1 - 1.7e-21 76.4 0.1 2e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 YCII-related domain DUF936 PF06075.12 EON32852.1 - 0.51 9.2 1.2 0.63 8.9 1.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) VanY PF02557.17 EON32853.1 - 4.2e-10 39.5 0.1 8.8e-10 38.5 0.1 1.5 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF3350 PF11830.8 EON32853.1 - 0.13 12.5 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) Peptidase_M15_3 PF08291.11 EON32853.1 - 0.15 12.2 0.0 4.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase M15 DUF2235 PF09994.9 EON32854.1 - 7.3e-77 258.5 0.0 1.4e-76 257.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyoxalase PF00903.25 EON32855.1 - 2.3e-15 56.9 0.0 2.6e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON32855.1 - 1e-05 26.2 0.1 2e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EON32855.1 - 0.0013 18.9 0.0 0.0021 18.3 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EON32855.1 - 0.12 12.5 0.1 2.3 8.3 0.1 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain HTH_20 PF12840.7 EON32856.1 - 3.2e-17 62.4 0.2 1.6e-16 60.1 0.6 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EON32856.1 - 7.3e-07 29.0 0.5 1.2e-05 25.1 0.8 2.5 2 1 0 2 2 2 1 MarR family HTH_5 PF01022.20 EON32856.1 - 6.5e-06 25.9 1.2 4.7e-05 23.2 1.2 2.0 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EON32856.1 - 1.8e-05 24.2 0.2 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding DUF2551 PF10826.8 EON32856.1 - 0.0044 17.2 0.0 0.0055 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2551) TrmB PF01978.19 EON32856.1 - 0.0047 16.8 0.0 0.007 16.2 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 EON32856.1 - 0.017 15.0 0.1 0.033 14.1 0.1 1.5 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Cdc6_C PF09079.11 EON32856.1 - 0.019 14.9 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_34 PF13601.6 EON32856.1 - 0.037 14.2 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 EON32856.1 - 0.047 13.7 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_27 PF13463.6 EON32856.1 - 0.093 13.2 0.1 0.34 11.4 0.1 1.9 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_11 PF08279.12 EON32856.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.7 1 1 0 1 1 1 0 HTH domain ABC_tran PF00005.27 EON32857.1 - 6.7e-29 101.1 0.0 8.9e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32857.1 - 3.1e-11 43.6 0.8 0.00015 21.7 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON32857.1 - 1.4e-05 25.6 0.5 2.2e-05 24.9 0.5 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EON32857.1 - 3.2e-05 23.8 1.1 6.5e-05 22.7 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON32857.1 - 9.3e-05 22.7 0.0 0.00026 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EON32857.1 - 0.00099 18.5 0.1 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EON32857.1 - 0.0023 17.6 0.1 0.0052 16.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON32857.1 - 0.0046 17.5 0.0 0.0072 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EON32857.1 - 0.0069 16.4 0.3 0.2 11.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EON32857.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EON32857.1 - 0.011 16.0 0.4 0.048 14.0 0.4 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EON32857.1 - 0.016 15.1 0.1 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_27 PF13514.6 EON32857.1 - 0.025 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON32857.1 - 0.027 14.7 0.6 0.062 13.5 0.7 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EON32857.1 - 0.031 13.7 0.1 0.34 10.3 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EON32857.1 - 0.033 14.1 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EON32857.1 - 0.042 14.1 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON32857.1 - 0.053 13.1 4.1 0.031 13.9 1.4 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EON32857.1 - 0.06 13.9 0.4 0.3 11.6 0.4 2.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EON32857.1 - 0.078 13.0 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EON32857.1 - 0.08 13.4 0.2 0.32 11.4 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_trans_4_5 PF16994.5 EON32857.1 - 0.11 12.2 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Glycosyl-transferase family 4 cobW PF02492.19 EON32857.1 - 0.15 11.7 0.6 0.3 10.6 0.4 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EON32857.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 EON32858.1 - 1.7e-47 161.9 88.8 2.4e-27 95.8 42.4 2.2 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EON32858.1 - 7.3e-29 101.0 0.0 1.1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32858.1 - 1e-11 45.2 1.3 7e-06 26.1 0.4 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 EON32858.1 - 2.9e-09 36.6 0.7 7.3e-09 35.3 0.7 1.8 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 EON32858.1 - 2e-06 27.4 0.3 8e-05 22.2 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON32858.1 - 3.8e-05 23.3 0.6 0.00011 21.9 0.6 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON32858.1 - 0.0001 22.9 0.5 0.00015 22.3 0.5 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON32858.1 - 0.00029 20.6 0.3 0.00056 19.7 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON32858.1 - 0.0073 16.7 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EON32858.1 - 0.042 13.6 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EON32858.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EON32858.1 - 0.19 11.8 0.2 0.48 10.5 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Peripla_BP_6 PF13458.6 EON32859.1 - 1.5e-40 139.9 10.7 1.8e-40 139.7 10.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EON32859.1 - 5.8e-06 25.6 0.0 1.1e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EON32859.1 - 0.00016 20.8 0.1 0.05 12.6 0.1 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain CUE PF02845.16 EON32859.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 CUE domain TetR_N PF00440.23 EON32860.1 - 4.9e-13 48.7 0.1 9.5e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 EON32860.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 EON32860.1 - 0.056 13.4 1.3 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_14 PF17754.1 EON32860.1 - 0.08 12.9 0.9 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 MftR C-terminal domain Peptidase_M23 PF01551.22 EON32862.1 - 1.5e-29 102.1 1.7 2.4e-29 101.4 1.7 1.3 1 0 0 1 1 1 1 Peptidase family M23 Biotin_lipoyl PF00364.22 EON32862.1 - 0.052 13.4 0.2 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme IclR PF01614.18 EON32863.1 - 4.6e-21 75.0 0.0 7.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EON32863.1 - 2.7e-13 49.5 0.0 5.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 EON32863.1 - 6.7e-06 25.9 0.1 7.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EON32863.1 - 5.1e-05 23.1 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 MarR family SMC_Nse1 PF07574.13 EON32863.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex RP-C PF03428.13 EON32863.1 - 0.00027 20.6 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Replication protein C N-terminal domain AbiEi_4 PF13338.6 EON32863.1 - 0.0004 20.5 0.3 0.12 12.6 0.0 3.0 2 1 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin Rrf2 PF02082.20 EON32863.1 - 0.0041 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 EON32863.1 - 0.029 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF1803 PF08820.10 EON32863.1 - 0.05 13.6 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) HTH_24 PF13412.6 EON32863.1 - 0.059 12.9 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EON32863.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 EON32863.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PEP_mutase PF13714.6 EON32864.1 - 2.2e-50 171.3 1.9 2.6e-50 171.1 1.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EON32864.1 - 7.1e-08 31.4 0.1 9.4e-08 31.0 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 EON32864.1 - 0.012 15.0 0.2 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Aconitase PF00330.20 EON32865.1 - 2.5e-68 231.2 0.3 1.4e-66 225.4 0.3 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 EON32865.1 - 2.9e-05 23.0 0.0 4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aconitase_C PF00694.19 EON32866.1 - 0.002 18.4 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Sugar_tr PF00083.24 EON32867.1 - 5.3e-43 147.5 27.0 1.1e-28 100.3 1.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON32867.1 - 5.8e-37 127.4 68.2 1.6e-29 103.0 35.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RHS_repeat PF05593.14 EON32869.1 - 9.7e-62 204.8 89.4 2.1e-08 34.5 5.1 19.7 15 6 5 21 21 21 15 RHS Repeat DUF4595 PF15283.6 EON32869.1 - 0.00013 22.1 0.3 1.9 8.5 0.1 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4595) with porin-like fold RHS PF03527.14 EON32869.1 - 5.4 6.9 9.4 31 4.4 0.0 5.0 4 1 1 5 5 5 0 RHS protein T7SS_ESX_EspC PF10824.8 EON32870.1 - 0.00068 20.1 0.0 0.0072 16.8 0.0 2.3 1 1 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm SseB PF07179.12 EON32871.1 - 2.6e-07 30.9 0.0 3.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 SseB protein N-terminal domain GIIM PF08388.11 EON32872.1 - 0.07 13.2 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Methyltransf_25 PF13649.6 EON32874.1 - 3.3e-15 56.6 0.0 5.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON32874.1 - 4.5e-11 43.3 0.0 7.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32874.1 - 5.9e-11 43.0 0.0 9.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32874.1 - 6.5e-09 35.8 0.0 8.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32874.1 - 2.5e-08 33.9 0.0 5.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EON32874.1 - 6.9e-08 32.1 0.0 8.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 EON32874.1 - 3.9e-06 26.5 0.0 0.00016 21.2 0.0 2.4 2 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.13 EON32874.1 - 0.00011 21.7 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EON32874.1 - 0.00014 21.5 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 EON32874.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 EON32874.1 - 0.0067 16.1 0.0 0.009 15.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EON32874.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 EON32874.1 - 0.033 13.5 0.0 0.065 12.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 EON32874.1 - 0.038 13.6 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 EON32874.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 DNA methylase UDPG_MGDP_dh_N PF03721.14 EON32874.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.19 EON32874.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase SnoaL_4 PF13577.6 EON32875.1 - 0.00071 19.7 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain PLDc_2 PF13091.6 EON32876.1 - 4.2e-09 36.4 0.0 6.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain SIR2_2 PF13289.6 EON32880.1 - 1.7e-20 73.6 0.0 4.6e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 SIR2-like domain zf-ribbon_3 PF13248.6 EON32881.1 - 0.00073 18.9 4.0 0.11 12.0 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EON32881.1 - 0.0087 16.2 1.2 1.2 9.3 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EON32881.1 - 0.06 13.1 5.5 2.1 8.2 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EON32881.1 - 0.063 12.8 0.3 0.28 10.7 0.2 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_13 PF09855.9 EON32881.1 - 0.17 12.1 0.2 1.2 9.4 0.2 2.1 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2387 PF09526.10 EON32881.1 - 0.2 11.8 1.6 1.2 9.3 1.2 2.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) DUF35_N PF12172.8 EON32881.1 - 0.27 11.2 3.2 6.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_UBZ PF18439.1 EON32881.1 - 0.4 10.3 2.8 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 EON32881.1 - 0.57 10.1 2.6 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 EON32881.1 - 0.6 10.1 5.3 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 EON32881.1 - 0.64 10.0 7.7 6 6.9 0.7 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-NADH-PPase PF09297.11 EON32881.1 - 1.3 8.8 5.2 15 5.4 1.2 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf_C2H2_10 PF18414.1 EON32881.1 - 1.5 8.4 4.5 3.1 7.4 0.4 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger Mu-like_Com PF10122.9 EON32881.1 - 1.9 8.0 4.7 16 5.1 0.1 2.9 3 0 0 3 3 3 0 Mu-like prophage protein Com UPF0547 PF10571.9 EON32881.1 - 3.1 8.0 7.1 4.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.11 EON32881.1 - 3.3 7.7 4.5 3.8 7.5 1.5 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-FPG_IleRS PF06827.14 EON32881.1 - 4.1 7.4 8.2 7.7 6.5 3.5 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS AAA_29 PF13555.6 EON32882.1 - 2.8e-21 75.0 0.1 6.6e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EON32882.1 - 4.2e-21 75.0 0.3 1.3e-20 73.4 0.1 2.0 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EON32882.1 - 7.7e-09 36.3 10.5 1.4e-08 35.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EON32882.1 - 8.3e-06 25.4 0.1 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MukB PF04310.12 EON32882.1 - 0.00033 20.5 0.1 0.00083 19.2 0.1 1.7 1 0 0 1 1 1 1 MukB N-terminal Spc7 PF08317.11 EON32882.1 - 0.002 17.1 8.1 0.0042 16.0 1.2 2.9 2 1 0 2 2 2 1 Spc7 kinetochore protein AAA_21 PF13304.6 EON32882.1 - 0.0044 16.9 0.4 0.0044 16.9 0.4 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NPV_P10 PF05531.12 EON32882.1 - 0.0077 16.7 5.6 0.2 12.2 2.4 3.3 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein AAA_15 PF13175.6 EON32882.1 - 0.0089 15.8 0.3 0.22 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF2730 PF10805.8 EON32882.1 - 0.031 14.3 0.1 1.5 9.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) AAA_27 PF13514.6 EON32882.1 - 0.033 13.8 0.5 0.15 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cas6 PF09559.10 EON32882.1 - 0.039 13.9 0.4 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Cas6 Crispr Phage_GP20 PF06810.11 EON32882.1 - 0.13 12.1 2.9 3.9 7.3 0.5 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 ABC_tran PF00005.27 EON32882.1 - 0.13 12.8 2.4 0.29 11.7 0.1 2.7 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 EON32882.1 - 0.16 12.3 0.1 0.16 12.3 0.1 3.7 2 1 0 2 2 1 0 AAA ATPase domain TMF_TATA_bd PF12325.8 EON32882.1 - 0.58 10.4 0.0 0.58 10.4 0.0 3.8 4 1 0 4 4 3 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EON32882.1 - 0.71 10.4 11.2 5.2 7.6 1.1 4.1 4 0 0 4 4 4 0 Cell division protein ZapB ADIP PF11559.8 EON32882.1 - 1.6 8.8 7.3 3 7.9 0.2 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EON32882.1 - 4.1 8.1 8.1 8.6 7.1 0.6 3.7 2 0 0 2 2 2 0 SlyX DUF4194 PF13835.6 EON32883.1 - 1.1e-34 119.6 4.4 1.4e-34 119.3 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) DUF3375 PF11855.8 EON32884.1 - 2.8e-103 346.4 12.1 3.1e-103 346.2 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) FliT PF05400.13 EON32884.1 - 2.4 9.0 5.8 6.3 7.7 0.3 3.3 2 1 2 4 4 4 0 Flagellar protein FliT Abhydrolase_3 PF07859.13 EON32885.1 - 9.7e-44 149.7 0.0 1.3e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON32885.1 - 1.4e-06 27.4 0.0 1.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase ACOX PF01756.19 EON32885.1 - 0.25 10.9 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase PLDc_N PF13396.6 EON32886.1 - 1e-08 35.0 5.1 1e-08 35.0 5.1 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF3043 PF11241.8 EON32886.1 - 0.14 12.2 3.9 5.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Zip PF02535.22 EON32887.1 - 0.00012 21.4 22.6 0.0019 17.5 9.6 2.6 1 1 1 2 2 2 2 ZIP Zinc transporter DrsE PF02635.15 EON32888.1 - 0.028 14.8 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family CN_hydrolase PF00795.22 EON32889.1 - 2.8e-42 144.8 0.0 3.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pyr_redox_3 PF13738.6 EON32891.1 - 1e-17 64.4 0.0 2.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON32891.1 - 8.8e-15 54.7 0.0 5.2e-13 48.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON32891.1 - 2.8e-10 39.9 0.0 7e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON32891.1 - 4.7e-07 29.7 1.0 0.0012 18.5 0.6 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON32891.1 - 1e-06 28.3 1.7 0.00012 21.5 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EON32891.1 - 3.4e-05 22.7 1.3 0.51 9.0 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EON32891.1 - 5.5e-05 23.3 0.7 0.017 15.3 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EON32891.1 - 0.00021 19.9 0.0 0.00036 19.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 EON32891.1 - 0.0008 19.9 0.1 1.5 9.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON32891.1 - 0.0013 17.9 2.7 0.12 11.4 0.7 3.1 3 0 0 3 3 3 1 FAD binding domain ApbA PF02558.16 EON32891.1 - 0.0046 16.6 0.7 0.27 10.9 0.1 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EON32891.1 - 0.0072 16.6 0.1 6.1 7.1 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.17 EON32891.1 - 0.012 14.8 0.6 0.048 12.9 0.1 1.9 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EON32891.1 - 0.013 14.6 3.6 0.063 12.4 0.5 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EON32891.1 - 0.016 14.3 0.7 0.31 10.0 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EON32891.1 - 0.031 14.3 1.6 7.3 6.6 0.0 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EON32891.1 - 0.033 13.5 0.3 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ThiF PF00899.21 EON32891.1 - 0.037 13.4 0.6 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 EON32891.1 - 0.11 12.4 0.8 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EON32891.1 - 0.11 12.5 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Radical_SAM PF04055.21 EON32892.1 - 9.1e-14 52.2 0.0 1.5e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ComX PF05952.12 EON32892.1 - 0.16 12.0 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Bacillus competence pheromone ComX AIRS PF00586.24 EON32893.1 - 7.8e-16 58.5 0.3 1.8e-15 57.3 0.3 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 EON32893.1 - 8.5e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Acetyltransf_10 PF13673.7 EON32893.1 - 4.6e-05 23.4 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON32893.1 - 0.00043 20.5 0.0 0.00088 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CN_hydrolase PF00795.22 EON32894.1 - 4.8e-36 124.4 0.0 6.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glycos_transf_1 PF00534.20 EON32895.1 - 1.3e-19 70.4 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON32895.1 - 4.6e-17 62.5 0.9 7.6e-17 61.8 0.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EON32895.1 - 1.3e-16 61.2 0.0 2.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON32895.1 - 2.9e-11 44.1 9.2 4.7e-11 43.4 2.0 3.2 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EON32895.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 EamA PF00892.20 EON32896.1 - 1.8e-22 80.0 35.7 1.4e-14 54.4 16.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EON32896.1 - 0.14 11.3 4.4 0.12 11.6 2.5 1.7 2 0 0 2 2 2 0 UAA transporter family DUF4407 PF14362.6 EON32896.1 - 1.1 8.5 8.9 1.3 8.3 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SnoaL_2 PF12680.7 EON32897.1 - 9.6e-10 39.0 1.4 1.5e-09 38.4 0.2 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 EON32897.1 - 0.00019 21.3 0.3 0.0027 17.5 0.3 2.1 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 EON32897.1 - 0.0091 16.4 0.1 0.017 15.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EON32897.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain Bac_luciferase PF00296.20 EON32898.1 - 9.8e-69 232.2 3.0 1.2e-68 231.9 3.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Polyketide_cyc2 PF10604.9 EON32899.1 - 1.1e-07 32.2 6.0 1.5e-07 31.8 6.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FKBP_C PF00254.28 EON32900.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase p450 PF00067.22 EON32901.1 - 6.5e-71 239.5 0.0 2.9e-70 237.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GT87 PF09594.10 EON32902.1 - 4.9e-60 203.2 30.8 4.9e-60 203.2 30.8 3.7 3 1 0 3 3 3 1 Glycosyltransferase family 87 DUF3810 PF12725.7 EON32902.1 - 6.8 5.9 6.1 0.35 10.2 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Globin PF00042.22 EON32903.1 - 4.5e-09 36.9 0.0 1.5e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Globin Bac_globin PF01152.21 EON32903.1 - 0.0075 16.4 0.0 0.016 15.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial-like globin RVT_1 PF00078.27 EON32904.1 - 3.2e-21 75.9 0.0 4.6e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acetyltransf_1 PF00583.25 EON32905.1 - 3.8e-07 30.3 0.0 4.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON32905.1 - 2.3e-06 27.9 0.0 2.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON32905.1 - 4.5e-06 26.5 0.0 6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EON32905.1 - 1.2e-05 25.2 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF222 PF02720.17 EON32906.1 - 3.9e-16 59.4 7.6 5e-16 59.1 7.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) RHS_repeat PF05593.14 EON32907.1 - 0.19 12.3 2.5 2 9.0 0.3 2.6 2 0 0 2 2 2 0 RHS Repeat ABC_membrane_2 PF06472.15 EON32908.1 - 1.7e-60 204.8 0.3 7.7e-42 143.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 EON32908.1 - 5e-19 68.9 1.4 2e-14 53.8 0.4 2.2 2 0 0 2 2 2 2 SbmA/BacA-like family ABC_tran PF00005.27 EON32908.1 - 2e-13 51.1 0.0 1.5e-12 48.2 0.0 2.1 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 EON32908.1 - 0.00088 19.2 0.4 0.0081 16.1 0.2 2.1 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 EON32908.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EON32908.1 - 0.035 13.8 0.1 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON32908.1 - 0.072 13.5 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain TM_helix PF05552.12 EON32908.1 - 0.13 12.3 3.7 0.11 12.5 0.9 2.3 2 0 0 2 2 2 0 Conserved TM helix AAA_29 PF13555.6 EON32908.1 - 0.16 11.7 0.3 0.37 10.6 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EON32908.1 - 0.21 11.8 0.1 0.65 10.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 EON32909.1 - 1.2e-95 320.7 0.5 1.4e-95 320.4 0.5 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1269 PF06897.12 EON32910.1 - 0.028 14.7 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) SHOCT PF09851.9 EON32911.1 - 1.6e-09 37.2 0.9 2.2e-09 36.7 0.9 1.2 1 0 0 1 1 1 1 Short C-terminal domain DUF4106 PF13388.6 EON32911.1 - 0.97 8.6 10.7 1 8.5 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) EutC PF05985.11 EON32912.1 - 4.9e-82 274.7 0.0 5.6e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) EutB PF06751.11 EON32913.1 - 1.3e-207 689.9 0.0 1.6e-207 689.6 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) TetR_N PF00440.23 EON32914.1 - 4.4e-10 39.2 0.2 1.1e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON32914.1 - 0.0029 17.8 8.5 0.0033 17.6 2.5 2.6 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 EON32914.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_1 PF00561.20 EON32915.1 - 1.5e-10 41.1 0.0 1.7e-07 31.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EON32915.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Dodecin PF07311.12 EON32916.1 - 2.5e-31 107.7 0.6 2.8e-31 107.6 0.6 1.0 1 0 0 1 1 1 1 Dodecin UPF0225 PF17775.1 EON32917.1 - 2.2e-25 89.3 0.0 2.6e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain ABM PF03992.16 EON32918.1 - 0.00044 20.3 0.7 0.0023 18.0 0.1 2.2 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Amidohydro_1 PF01979.20 EON32919.1 - 7.4e-42 143.9 0.0 8.9e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON32919.1 - 1.9e-11 44.2 0.9 7.7e-08 32.2 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family ABM PF03992.16 EON32920.1 - 7e-07 29.3 0.9 0.0001 22.3 0.4 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 EON32920.1 - 0.084 13.2 0.0 9.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DUF2461 PF09365.10 EON32921.1 - 1.5e-50 172.1 0.0 1.7e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CHAP PF05257.16 EON32922.1 - 3.7e-12 46.6 0.3 7.2e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 CHAP domain DUF2272 PF10030.9 EON32922.1 - 1.6e-07 31.3 1.4 2.1e-06 27.6 1.2 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) Amidase_6 PF12671.7 EON32922.1 - 0.00073 19.7 0.4 0.082 13.0 0.4 2.1 1 1 0 1 1 1 1 Putative amidase domain RskA PF10099.9 EON32922.1 - 0.0095 16.3 6.5 0.014 15.7 6.5 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PLDc_2 PF13091.6 EON32923.1 - 2.3e-14 53.4 0.0 2.2e-10 40.5 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EON32923.1 - 8.2e-11 41.6 1.0 0.00072 19.6 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif TetR_C_35 PF18556.1 EON32924.1 - 5.3e-31 106.9 0.5 8.7e-31 106.2 0.5 1.3 1 0 0 1 1 1 1 Bacterial Tetracyclin repressor, C-terminal domain TetR_N PF00440.23 EON32924.1 - 2e-07 30.7 0.0 4.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 EON32924.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 EON32924.1 - 0.07 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 EON32924.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_22 PF13309.6 EON32924.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 HTH domain Pyr_redox_2 PF07992.14 EON32925.1 - 6.3e-53 179.9 0.3 7.5e-53 179.7 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32925.1 - 9.1e-20 71.0 1.8 6.9e-14 52.2 0.1 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON32925.1 - 6.2e-09 36.0 0.9 0.0015 18.7 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EON32925.1 - 1.9e-08 33.9 0.0 6.8e-06 25.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON32925.1 - 2.5e-07 30.6 13.3 0.049 13.2 5.0 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON32925.1 - 3.1e-07 29.8 12.7 0.052 12.6 0.0 4.5 4 1 1 5 5 5 3 FAD binding domain Reductase_C PF14759.6 EON32925.1 - 1.9e-06 28.3 0.0 6.2e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.14 EON32925.1 - 2.3e-06 26.6 2.3 0.39 9.4 0.4 3.2 3 0 0 3 3 3 3 HI0933-like protein NAD_binding_9 PF13454.6 EON32925.1 - 4.3e-05 23.5 7.3 0.55 10.2 0.1 3.7 4 1 0 4 4 3 2 FAD-NAD(P)-binding GIDA PF01134.22 EON32925.1 - 0.0003 20.0 2.7 0.2 10.7 0.5 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EON32925.1 - 0.0021 17.4 6.3 0.21 10.8 0.6 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EON32925.1 - 0.0023 17.2 1.9 0.86 8.8 0.2 2.4 2 0 0 2 2 2 2 Thi4 family TrkA_N PF02254.18 EON32925.1 - 0.0039 17.4 0.7 1.4 9.2 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.19 EON32925.1 - 0.0059 15.9 5.9 0.19 10.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EON32925.1 - 0.0079 15.3 7.9 0.03 13.4 1.1 2.9 3 1 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EON32925.1 - 0.015 14.2 3.2 1.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 EON32925.1 - 0.099 11.8 0.2 0.35 10.0 0.1 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EON32925.1 - 0.11 12.4 1.6 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.24 EON32925.1 - 0.14 11.9 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 DJ-1/PfpI family ThiF PF00899.21 EON32925.1 - 1 8.7 2.6 17 4.7 0.2 2.1 2 0 0 2 2 2 0 ThiF family Sacchrp_dh_NADP PF03435.18 EON32925.1 - 1 9.6 2.5 15 5.8 0.9 2.9 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 EON32925.1 - 1.9 7.7 11.5 1.4 8.2 2.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Rubredoxin PF00301.20 EON32926.1 - 7.9e-23 80.2 4.6 8.9e-23 80.1 4.6 1.0 1 0 0 1 1 1 1 Rubredoxin OrfB_Zn_ribbon PF07282.11 EON32926.1 - 0.014 15.3 0.3 2 8.4 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HypA PF01155.19 EON32926.1 - 0.019 15.0 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 EON32926.1 - 0.024 14.4 6.4 0.44 10.3 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-RRN7 PF11781.8 EON32926.1 - 0.029 14.0 1.2 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 EON32926.1 - 0.048 13.8 5.5 0.3 11.3 5.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf_UBZ PF18439.1 EON32926.1 - 0.069 12.8 0.8 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 EON32926.1 - 0.089 12.5 1.8 5.6 6.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 EON32926.1 - 0.099 12.5 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn_Tnp_IS1595 PF12760.7 EON32926.1 - 0.2 11.6 2.9 2.3 8.2 0.1 2.4 2 1 1 3 3 3 0 Transposase zinc-ribbon domain RbpA PF13397.6 EON32926.1 - 0.23 12.1 0.7 0.3 11.7 0.3 1.4 1 1 1 2 2 2 0 RNA polymerase-binding protein NRDD PF13597.6 EON32926.1 - 0.26 10.0 0.0 0.26 10.0 0.0 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase zf-C2H2 PF00096.26 EON32926.1 - 0.71 10.5 2.8 19 5.9 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type PHD_4 PF16866.5 EON32926.1 - 1.2 9.2 6.0 5.3 7.2 6.0 1.9 1 1 0 1 1 1 0 PHD-finger Rubredoxin PF00301.20 EON32927.1 - 5.8e-21 74.3 6.2 7.1e-21 74.0 6.2 1.1 1 0 0 1 1 1 1 Rubredoxin Zn_Tnp_IS1595 PF12760.7 EON32927.1 - 0.011 15.7 0.1 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EON32927.1 - 0.011 15.6 1.0 0.13 12.2 1.0 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 EON32927.1 - 0.014 14.8 1.9 1.5 8.3 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EON32927.1 - 0.031 13.8 0.7 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 EON32927.1 - 0.055 13.9 1.9 0.81 10.2 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-ISL3 PF14690.6 EON32927.1 - 0.068 13.9 0.3 1.2 9.9 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_10 PF10058.9 EON32927.1 - 0.17 11.7 1.3 14 5.5 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 EON32927.1 - 0.29 11.3 3.3 2.5 8.3 3.3 2.0 1 1 0 1 1 1 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 EON32927.1 - 0.57 10.7 2.3 0.94 10.0 0.1 2.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 EON32927.1 - 0.69 10.5 3.9 5 7.8 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type PHD_4 PF16866.5 EON32927.1 - 1.2 9.2 5.2 3.4 7.8 5.2 1.8 1 1 0 1 1 1 0 PHD-finger FA_desaturase PF00487.24 EON32928.1 - 2e-29 103.2 6.9 2e-29 103.2 6.9 2.2 2 0 0 2 2 2 2 Fatty acid desaturase DUF222 PF02720.17 EON32929.1 - 7.5e-26 91.3 12.8 9.5e-26 91.0 12.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 EON32929.1 - 9.4e-09 35.3 11.9 1.9e-08 34.3 11.9 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON32929.1 - 0.023 14.6 6.2 0.043 13.7 6.2 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF456 PF04306.13 EON32930.1 - 0.0044 17.3 4.9 0.0094 16.2 4.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.15 EON32930.1 - 0.0044 16.8 18.2 0.07 13.0 7.2 2.6 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 EON32930.1 - 0.39 10.5 21.5 0.24 11.2 16.9 2.8 2 1 1 3 3 3 0 Glycine-zipper domain DUF1269 PF06897.12 EON32930.1 - 0.75 10.1 12.1 0.18 12.1 7.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.6 EON32930.1 - 9 6.4 29.3 0.072 13.1 20.0 2.4 3 1 0 3 3 3 0 Glycine zipper Aldedh PF00171.22 EON32931.1 - 1.2e-46 159.2 0.1 3.9e-46 157.5 0.1 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DHDPS PF00701.22 EON32932.1 - 9.3e-54 182.1 0.0 1.1e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.6 EON32933.1 - 7.7e-51 172.8 0.0 1.2e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EON32933.1 - 2.7e-07 30.8 0.4 7.6e-07 29.3 0.4 1.8 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain LysR_substrate PF03466.20 EON32934.1 - 2.9e-36 124.8 4.7 2.9e-36 124.8 4.7 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EON32934.1 - 5.5e-22 77.5 1.1 1.1e-21 76.6 1.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Usp PF00582.26 EON32935.1 - 3.4e-10 40.6 0.9 2.1e-09 38.0 0.9 2.0 1 1 0 1 1 1 1 Universal stress protein family 2-Hacid_dh_C PF02826.19 EON32936.1 - 2e-48 164.1 0.0 3e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON32936.1 - 8.3e-22 77.3 0.0 9.6e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EON32936.1 - 1.9e-06 28.1 0.0 4.4e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EON32936.1 - 0.026 15.1 0.7 0.12 13.0 0.7 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EON32936.1 - 0.044 13.4 0.3 0.12 12.0 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EON32936.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family SBP_bac_5 PF00496.22 EON32937.1 - 5.7e-58 196.7 0.2 7.3e-58 196.3 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EON32938.1 - 8.7e-34 116.9 15.5 8.7e-34 116.9 15.5 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component FA_desaturase PF00487.24 EON32938.1 - 5.8 6.7 9.5 0.34 10.7 4.0 1.7 2 0 0 2 2 2 0 Fatty acid desaturase BPD_transp_1 PF00528.22 EON32939.1 - 3.8e-20 72.4 13.4 3.8e-20 72.4 13.4 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EON32939.1 - 1e-07 31.8 0.1 1e-07 31.8 0.1 3.1 3 1 1 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C Dppa2_A PF14049.6 EON32939.1 - 0.013 15.7 0.5 0.024 14.7 0.5 1.4 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates ABC_tran PF00005.27 EON32940.1 - 4.9e-27 95.1 0.0 7.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EON32940.1 - 8.3e-19 67.9 0.0 1.9e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EON32940.1 - 9.6e-07 28.9 0.7 2.3e-05 24.4 0.1 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON32940.1 - 0.0015 18.8 0.5 0.013 15.8 0.5 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EON32940.1 - 0.0015 17.9 0.0 0.0059 16.0 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EON32940.1 - 0.014 14.8 0.3 1.8 7.9 0.1 2.5 3 0 0 3 3 3 0 Bacterial TniB protein SMC_N PF02463.19 EON32940.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EON32940.1 - 0.018 15.4 0.2 0.2 12.1 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EON32940.1 - 0.048 13.2 0.7 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EON32940.1 - 0.068 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EON32940.1 - 0.083 13.3 0.4 0.13 12.6 0.4 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EON32940.1 - 0.15 12.1 0.2 0.56 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EON32940.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EON32941.1 - 8.2e-33 113.8 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EON32941.1 - 8.5e-20 71.1 0.3 2e-19 69.9 0.3 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EON32941.1 - 3.9e-07 30.2 0.2 0.00018 21.4 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON32941.1 - 3.8e-05 24.0 0.8 0.0017 18.6 0.8 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON32941.1 - 0.00052 20.4 0.5 0.0011 19.3 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EON32941.1 - 0.001 18.6 0.0 0.0018 17.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TniB PF05621.11 EON32941.1 - 0.0022 17.4 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 EON32941.1 - 0.0041 17.1 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_13 PF13166.6 EON32941.1 - 0.009 14.7 0.1 0.088 11.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EON32941.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EON32941.1 - 0.021 14.9 0.7 0.3 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EON32941.1 - 0.031 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EON32941.1 - 0.078 13.4 0.0 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EON32941.1 - 0.1 12.8 0.2 0.18 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EON32941.1 - 0.1 12.3 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EON32941.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EON32941.1 - 0.16 12.5 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EON32941.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TauE PF01925.19 EON32942.1 - 5.6e-17 62.2 39.0 7e-17 61.9 39.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE VIT1 PF01988.19 EON32942.1 - 0.0051 16.7 2.6 0.0051 16.7 2.6 2.7 2 1 1 3 3 3 1 VIT family MR_MLE_C PF13378.6 EON32943.1 - 1.1e-39 136.3 0.6 1.6e-39 135.7 0.6 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EON32943.1 - 0.0019 18.4 0.1 0.0042 17.3 0.1 1.7 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 2-Hacid_dh_C PF02826.19 EON32944.1 - 2.7e-39 134.4 0.0 3.6e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON32944.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 EON32944.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MIP PF00230.20 EON32945.1 - 8.9e-50 169.5 11.2 1.1e-49 169.2 11.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4395 PF14340.6 EON32945.1 - 2.2 8.6 9.5 0.61 10.4 2.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) Pirin PF02678.16 EON32946.1 - 3.8e-26 91.2 0.1 5.8e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 EON32946.1 - 2.1e-06 27.8 0.0 7.6e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 EON32946.1 - 0.01 15.5 1.1 0.087 12.5 0.2 2.6 2 1 0 2 2 2 0 Cupin domain DUF1345 PF07077.11 EON32947.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1345) SH3_2 PF07653.17 EON32948.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain FAD_binding_2 PF00890.24 EON32950.1 - 8.2e-90 301.8 3.1 1.2e-89 301.3 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EON32950.1 - 1.1e-21 77.1 0.1 2.8e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EON32950.1 - 2.6e-09 36.7 0.4 1.1e-05 24.8 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON32950.1 - 7.6e-05 22.4 3.2 0.001 18.7 2.9 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EON32950.1 - 0.0001 21.2 2.1 0.00081 18.2 0.3 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 EON32950.1 - 0.00055 19.1 1.9 0.0038 16.4 1.4 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EON32950.1 - 0.018 14.3 1.4 0.26 10.5 0.2 3.0 3 1 0 4 4 4 0 Thi4 family Pyr_redox_3 PF13738.6 EON32950.1 - 0.12 11.6 0.3 0.5 9.6 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON32950.1 - 0.93 8.8 4.7 1.5 8.1 4.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Fer2_3 PF13085.6 EON32951.1 - 8.8e-27 93.3 0.0 1.7e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 EON32951.1 - 3.6e-13 49.8 5.8 3.6e-13 49.8 5.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EON32951.1 - 3.4e-05 23.7 0.3 3.4e-05 23.7 0.3 2.2 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EON32951.1 - 6.2e-05 23.5 5.7 6.2e-05 23.5 5.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EON32951.1 - 0.00022 21.8 4.7 0.00029 21.3 1.0 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 EON32951.1 - 0.003 17.7 7.6 0.23 11.6 0.3 2.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain DUF1126 PF06565.12 EON32951.1 - 0.033 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 DUF1126 PH-like domain Fer4_9 PF13187.6 EON32951.1 - 0.72 10.1 15.0 2.7 8.2 2.8 3.2 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 EON32951.1 - 3.7 7.7 17.4 3.2 8.0 2.8 3.1 2 1 2 4 4 4 0 4Fe-4S dicluster domain Acyl-CoA_dh_1 PF00441.24 EON32952.1 - 6.3e-42 143.3 0.2 8.7e-42 142.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON32952.1 - 5.7e-34 117.2 0.0 1e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON32952.1 - 2.2e-26 91.9 0.0 4.7e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON32952.1 - 4.9e-12 46.3 0.0 7.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EON32952.1 - 0.0032 18.0 0.0 0.0054 17.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal WcbI PF18588.1 EON32953.1 - 1.7e-62 210.7 0.4 2.3e-62 210.3 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis enzyme WcbI Glyco_trans_4_4 PF13579.6 EON32954.1 - 0.0019 18.7 11.2 0.078 13.4 6.3 3.3 2 2 0 2 2 2 2 Glycosyl transferase 4-like domain Glycos_transf_2 PF00535.26 EON32955.1 - 5.1e-19 68.7 0.1 8.3e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32955.1 - 8.9e-13 48.6 2.9 3.8e-12 46.6 2.9 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON32955.1 - 9.7e-13 48.2 0.0 8.4e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 EON32955.1 - 9.3e-08 31.6 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 EON32955.1 - 0.002 17.6 0.0 0.28 10.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EON32955.1 - 0.0034 17.3 1.0 0.0098 15.8 1.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 AMP-binding PF00501.28 EON32956.1 - 3e-46 157.9 0.0 3.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EON32956.1 - 6.1e-10 38.9 2.8 1.2e-09 37.9 2.8 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EON32956.1 - 1.6e-05 25.8 0.1 4.1e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAA_hydrolase PF01557.18 EON32957.1 - 1e-59 201.9 0.0 1.3e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FMN_red PF03358.15 EON32958.1 - 2.3e-30 105.4 0.0 3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON32958.1 - 0.00023 20.9 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold preATP-grasp_3 PF18301.1 EON32958.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 pre ATP-grasp 3 domain SnoaL_4 PF13577.6 EON32959.1 - 6e-08 32.9 0.0 7.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 EON32959.1 - 0.00059 19.9 0.1 0.00075 19.6 0.1 1.1 1 0 0 1 1 1 1 Ring hydroxylating beta subunit TPP_enzyme_C PF02775.21 EON32960.1 - 2.5e-49 167.0 3.4 3.5e-48 163.3 0.0 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON32960.1 - 2.5e-49 166.5 0.8 4.6e-49 165.7 0.8 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 EON32960.1 - 5.5e-47 159.6 5.2 2.2e-46 157.6 3.9 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CoA_binding_2 PF13380.6 EON32960.1 - 0.004 17.6 0.5 1.2 9.7 0.0 2.9 3 0 0 3 3 3 1 CoA binding domain DUF5612 PF18462.1 EON32960.1 - 0.021 14.6 0.1 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) MtrD PF04207.12 EON32960.1 - 2.7 7.6 10.8 0.33 10.6 5.2 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D GlyL_C PF12524.8 EON32961.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 1 0 1 1 1 0 dsDNA virus glycoprotein L C terminal 2-oxoacid_dh PF00198.23 EON32962.1 - 7e-70 235.1 0.0 9.2e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EON32962.1 - 1.2e-21 76.3 0.2 2.5e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EON32962.1 - 0.00072 20.2 0.5 0.3 11.8 0.2 2.7 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EON32962.1 - 0.0054 16.5 0.4 0.77 9.6 0.7 3.1 2 1 1 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 EON32962.1 - 0.14 12.0 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein Transketolase_N PF00456.21 EON32963.1 - 8.2e-18 64.4 0.0 1.6e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain PDH_E1_M PF17831.1 EON32963.1 - 3.4e-15 56.2 0.0 5.4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_C PF02780.20 EON32963.1 - 1.7e-06 28.0 0.0 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EON32963.1 - 0.00039 19.7 0.0 0.0017 17.6 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase AsnC_trans_reg PF01037.21 EON32964.1 - 5.1e-18 64.8 0.5 1.1e-17 63.8 0.2 1.7 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 EON32964.1 - 7.7e-10 38.4 3.1 1.5e-09 37.5 3.1 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EON32964.1 - 9.7e-08 31.5 0.2 1.7e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON32964.1 - 1.3e-05 25.0 1.4 5.9e-05 22.9 0.6 2.3 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 EON32964.1 - 0.00036 20.3 0.1 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EON32964.1 - 0.0021 18.1 2.6 0.0049 16.9 0.8 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain NapD PF03927.13 EON32964.1 - 0.0074 16.3 0.6 0.027 14.5 0.4 1.8 2 0 0 2 2 2 1 NapD protein HTH_11 PF08279.12 EON32964.1 - 0.014 15.3 1.8 0.014 15.3 0.1 1.9 3 0 0 3 3 3 0 HTH domain HTH_30 PF13556.6 EON32964.1 - 0.023 14.5 0.3 0.068 13.0 0.3 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_36 PF13730.6 EON32964.1 - 0.023 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DprA_WH PF17782.1 EON32964.1 - 0.024 14.7 2.7 0.044 13.9 1.5 2.0 2 0 0 2 2 2 0 DprA winged helix domain ACT_4 PF13291.6 EON32964.1 - 0.03 14.9 0.2 0.18 12.4 0.2 2.0 1 1 0 1 1 1 0 ACT domain Replic_Relax PF13814.6 EON32964.1 - 0.036 14.1 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation HTH_IclR PF09339.10 EON32964.1 - 0.064 13.1 3.1 0.19 11.5 3.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain ATPgrasp_N PF18130.1 EON32964.1 - 0.074 13.6 0.0 0.14 12.7 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp N-terminal domain HTH_41 PF14502.6 EON32964.1 - 0.1 12.3 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain GntR PF00392.21 EON32965.1 - 7.3e-17 60.8 0.2 1.3e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EON32965.1 - 4.7e-16 59.3 8.9 7.9e-16 58.6 8.9 1.3 1 0 0 1 1 1 1 FCD domain TrmB PF01978.19 EON32965.1 - 0.015 15.2 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.12 EON32965.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 EON32965.1 - 0.025 14.2 0.0 0.074 12.6 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EON32965.1 - 0.028 14.9 0.0 0.18 12.3 0.0 2.2 1 1 0 2 2 2 0 Winged helix DNA-binding domain DUF3253 PF11625.8 EON32965.1 - 0.068 13.4 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DprA_WH PF17782.1 EON32965.1 - 0.068 13.3 0.6 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 DprA winged helix domain Fe_dep_repress PF01325.19 EON32965.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 EON32965.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Glyoxalase PF00903.25 EON32966.1 - 3e-10 40.4 0.1 4e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON32966.1 - 0.00038 20.7 0.1 0.001 19.3 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DoxX PF07681.12 EON32967.1 - 1.7e-09 38.2 11.3 1.7e-09 38.2 11.3 1.9 2 0 0 2 2 2 1 DoxX HR_lesion PF05514.11 EON32967.1 - 1.2e-07 32.0 1.1 0.0013 18.9 0.3 2.1 1 1 1 2 2 2 2 HR-like lesion-inducing DoxX_2 PF13564.6 EON32967.1 - 0.0017 18.4 7.1 0.0017 18.4 7.1 1.8 1 1 1 2 2 2 1 DoxX-like family SURF4 PF02077.15 EON32967.1 - 0.019 14.5 1.0 0.035 13.7 0.6 1.5 1 1 1 2 2 2 0 SURF4 family DUF2244 PF10003.9 EON32967.1 - 8.1 6.1 6.9 8.8 6.0 6.2 1.5 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) FAD_binding_3 PF01494.19 EON32968.1 - 4e-79 266.4 1.2 5.2e-79 266.0 1.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON32968.1 - 1.7e-05 24.2 0.2 0.01 15.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32968.1 - 0.00099 19.6 0.0 0.26 11.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EON32968.1 - 0.028 13.5 0.5 27 3.7 0.0 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 EON32968.1 - 0.032 13.8 4.7 0.18 11.4 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON32968.1 - 0.083 12.1 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HTH_30 PF13556.6 EON32969.1 - 1.7e-11 43.7 0.5 1.7e-11 43.7 0.5 2.3 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EON32969.1 - 2.2e-07 31.1 0.1 1.1e-06 28.9 0.1 2.2 1 0 0 1 1 1 1 GGDEF-like domain HTH_28 PF13518.6 EON32969.1 - 0.076 13.1 0.2 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EON32969.1 - 3.1 7.3 7.8 0.67 9.4 0.1 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 Glyoxalase PF00903.25 EON32970.1 - 1.9e-09 37.8 0.0 3.5e-09 36.9 0.0 1.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 EON32971.1 - 5e-97 325.3 0.0 6.1e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON32971.1 - 8.3e-05 22.0 0.0 0.00099 18.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON32971.1 - 0.00037 19.7 1.1 0.061 12.4 0.1 2.4 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EON32971.1 - 0.0017 18.0 4.1 0.23 11.0 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON32971.1 - 0.0023 17.2 0.0 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON32971.1 - 0.0035 17.9 0.0 0.05 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON32971.1 - 0.045 12.4 0.0 5.8 5.5 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EON32971.1 - 0.13 12.5 0.3 0.38 11.0 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SnoaL_2 PF12680.7 EON32973.1 - 1.7e-11 44.6 0.2 2e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EON32973.1 - 0.00073 19.7 0.0 0.00082 19.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EON32973.1 - 0.00083 19.2 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 EON32973.1 - 0.0059 16.9 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain FAD_binding_4 PF01565.23 EON32974.1 - 5.3e-29 100.7 2.1 5.3e-29 100.7 2.1 2.7 2 0 0 2 2 2 1 FAD binding domain Bac_luciferase PF00296.20 EON32974.1 - 3.9e-19 69.2 11.9 1.8e-18 67.1 11.9 2.1 1 1 0 1 1 1 1 Luciferase-like monooxygenase BBE PF08031.12 EON32974.1 - 2e-05 24.6 0.1 3.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Bac_luciferase PF00296.20 EON32975.1 - 1.7e-43 149.2 3.0 1.7e-43 149.2 3.0 1.9 2 0 0 2 2 2 1 Luciferase-like monooxygenase MarR_2 PF12802.7 EON32976.1 - 2.1e-10 40.3 2.1 4.3e-10 39.3 1.0 2.1 2 1 0 2 2 2 1 MarR family MarR PF01047.22 EON32976.1 - 1.5e-08 34.4 0.1 4.4e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EON32976.1 - 2.3e-05 24.8 0.1 7.6e-05 23.1 0.1 1.9 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_34 PF13601.6 EON32976.1 - 0.00048 20.3 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 EON32976.1 - 0.048 13.5 0.0 0.34 10.8 0.0 2.1 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 EON32976.1 - 0.13 12.3 0.5 0.92 9.5 0.5 2.3 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain PSD4 PF07631.11 EON32976.1 - 0.26 11.8 3.2 1.5 9.4 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Response_reg PF00072.24 EON32977.1 - 1.3e-28 99.4 0.5 2.2e-28 98.6 0.5 1.4 1 0 0 1 1 1 1 Response regulator receiver domain ANTAR PF03861.14 EON32977.1 - 1.3e-19 69.8 3.9 1.7e-19 69.4 2.6 1.9 2 0 0 2 2 2 1 ANTAR domain Peripla_BP_6 PF13458.6 EON32978.1 - 5e-35 121.8 10.1 6.7e-35 121.3 10.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EON32978.1 - 2.9e-20 72.7 0.0 3.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EON32978.1 - 9.6e-10 38.0 0.1 1.8e-09 37.1 0.0 1.4 2 0 0 2 2 2 1 Periplasmic binding protein domain Fe-ADH PF00465.19 EON32978.1 - 0.0074 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase LppC PF04348.13 EON32978.1 - 0.1 11.4 0.7 0.15 10.9 0.7 1.2 1 0 0 1 1 1 0 LppC putative lipoprotein DUF3558 PF12079.8 EON32978.1 - 0.33 10.9 6.8 0.72 9.8 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) ABC_tran PF00005.27 EON32979.1 - 1.2e-31 110.1 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32979.1 - 1.8e-10 41.1 0.2 1.7e-05 24.8 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EON32979.1 - 0.00027 21.5 0.5 0.00039 21.0 0.5 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EON32979.1 - 0.00039 19.9 0.2 0.023 14.1 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON32979.1 - 0.0046 17.2 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON32979.1 - 0.0047 16.6 0.1 0.009 15.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON32979.1 - 0.0089 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON32979.1 - 0.0091 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Mg_chelatase PF01078.21 EON32979.1 - 0.015 14.7 0.1 0.36 10.2 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EON32979.1 - 0.018 15.1 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EON32979.1 - 0.032 14.4 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EON32979.1 - 0.032 13.2 0.1 0.06 12.3 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EON32979.1 - 0.067 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON32979.1 - 0.07 12.8 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EON32979.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 EON32979.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EON32979.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON32980.1 - 3.5e-27 95.6 0.0 5.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32980.1 - 2.8e-11 43.8 0.7 8.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 EON32980.1 - 0.00097 19.0 0.1 0.0021 18.0 0.1 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 EON32980.1 - 0.0013 19.3 0.5 0.0022 18.6 0.5 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EON32980.1 - 0.0014 18.1 0.3 0.017 14.5 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EON32980.1 - 0.004 16.9 0.0 0.07 12.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EON32980.1 - 0.038 13.7 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EON32980.1 - 0.042 14.1 0.1 5.3 7.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EON32980.1 - 0.046 14.2 0.2 3.6 8.0 0.3 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GHL6 PF14871.6 EON32980.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 BPD_transp_2 PF02653.16 EON32981.1 - 3.5e-48 164.1 29.2 4.3e-48 163.8 29.2 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component GT87 PF09594.10 EON32981.1 - 0.41 10.3 22.9 0.017 14.9 13.4 2.5 1 1 0 2 2 2 0 Glycosyltransferase family 87 BPD_transp_2 PF02653.16 EON32982.1 - 1.8e-40 138.8 35.5 2.6e-40 138.3 35.5 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component CarboxypepD_reg PF13620.6 EON32982.1 - 7.6e-06 26.1 0.4 1.4e-05 25.3 0.4 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EON32982.1 - 0.0053 17.0 0.1 0.0093 16.2 0.1 1.3 1 0 0 1 1 1 1 SdrD B-like domain SpaA PF17802.1 EON32982.1 - 0.013 15.8 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Prealbumin-like fold domain Acetyltransf_1 PF00583.25 EON32983.1 - 0.00021 21.5 0.0 0.00034 20.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON32983.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON32983.1 - 0.0025 17.7 0.0 0.0099 15.8 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DNA_pol_A PF00476.20 EON32984.1 - 1.9e-142 474.8 0.0 2.4e-142 474.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 EON32984.1 - 2.7e-55 186.6 0.0 5.6e-55 185.6 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EON32984.1 - 3.6e-27 94.8 0.0 1e-26 93.4 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EON32984.1 - 0.016 15.3 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EON32984.1 - 0.035 14.7 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EON32984.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda NYN_YacP PF05991.11 EON32984.1 - 0.081 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 YacP-like NYN domain Iso_dh PF00180.20 EON32985.1 - 8.3e-84 281.7 0.0 9.4e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UCR_14kD PF02271.16 EON32985.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit SBP_bac_3 PF00497.20 EON32986.1 - 4.7e-46 157.0 0.4 6e-46 156.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EON32986.1 - 0.022 15.0 0.0 0.2 11.9 0.0 2.2 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site BPD_transp_1 PF00528.22 EON32987.1 - 2.2e-15 56.9 11.7 2.2e-15 56.9 11.7 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5592 PF17332.2 EON32987.1 - 0.037 14.6 0.3 0.3 11.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5592) MHYT PF03707.16 EON32987.1 - 0.045 13.9 0.4 0.045 13.9 0.4 3.3 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat BIV_Env PF05858.12 EON32987.1 - 0.23 9.6 0.6 0.32 9.1 0.6 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) ABC_tran PF00005.27 EON32988.1 - 3.1e-32 111.9 0.0 4.1e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON32988.1 - 2e-11 44.3 0.0 9.9e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON32988.1 - 4.8e-08 32.7 0.0 3.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON32988.1 - 0.00029 20.5 0.0 0.00081 19.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON32988.1 - 0.00084 19.8 0.0 0.0012 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON32988.1 - 0.0019 18.4 0.0 0.0029 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EON32988.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.15 EON32988.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EON32988.1 - 0.017 15.0 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EON32988.1 - 0.018 15.2 0.1 0.026 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EON32988.1 - 0.035 14.6 0.0 0.054 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON32988.1 - 0.048 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON32988.1 - 0.05 13.8 0.3 0.78 10.0 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EON32988.1 - 0.052 13.3 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 EON32988.1 - 0.053 12.3 0.2 0.9 8.3 0.1 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 EON32988.1 - 0.055 13.0 0.2 0.13 11.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EON32988.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EON32988.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Methyltransf_11 PF08241.12 EON32989.1 - 4.3e-20 72.2 0.0 7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32989.1 - 1.5e-19 70.5 0.1 3.1e-19 69.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON32989.1 - 8.2e-13 48.2 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EON32989.1 - 2.2e-08 34.8 0.0 3.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32989.1 - 2.1e-07 30.9 0.1 3.9e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON32989.1 - 2.4e-07 30.7 0.0 3.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EON32989.1 - 5.4e-07 28.5 0.1 7.5e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 EON32989.1 - 0.029 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.11 EON32989.1 - 0.033 13.8 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) BTAD PF03704.17 EON32990.1 - 9.6e-30 103.9 10.5 2e-29 102.9 3.1 3.4 3 0 0 3 3 3 1 Bacterial transcriptional activator domain AAA_16 PF13191.6 EON32990.1 - 5.2e-09 36.7 1.6 2.1e-08 34.7 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EON32990.1 - 8.7e-09 35.8 0.0 2.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Trans_reg_C PF00486.28 EON32990.1 - 7.9e-06 25.9 0.2 0.0004 20.4 0.0 3.0 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal AAA_5 PF07728.14 EON32990.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EON32990.1 - 0.0052 16.4 4.4 0.006 16.2 0.7 2.9 2 1 0 2 2 2 1 AAA domain TPR_MalT PF17874.1 EON32990.1 - 0.0071 15.8 0.5 0.36 10.1 0.0 2.6 2 0 0 2 2 2 1 MalT-like TPR region NB-ARC PF00931.22 EON32990.1 - 0.014 14.6 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 EON32990.1 - 0.038 14.5 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EON32990.1 - 0.054 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EON32990.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.6 EON32990.1 - 0.076 13.3 6.1 2.2 8.6 0.0 5.0 6 1 0 7 7 5 0 Tetratricopeptide repeat Cohesin_load PF10345.9 EON32990.1 - 0.077 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Cohesin loading factor TsaE PF02367.17 EON32990.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EON32990.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EON32990.1 - 0.22 11.6 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.6 EON32991.1 - 1.5e-17 63.8 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON32991.1 - 1.7e-14 54.3 0.1 4.8e-14 52.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON32991.1 - 3.4e-13 50.1 0.1 6.7e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON32991.1 - 1.4e-10 41.3 0.0 3.2e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON32991.1 - 1.1e-09 38.9 0.0 2.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON32991.1 - 4e-07 29.7 0.0 9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EON32991.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EON32991.1 - 6.9e-06 25.6 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EON32991.1 - 7.6e-06 25.5 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EON32991.1 - 4.1e-05 23.0 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EON32991.1 - 6.4e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EON32991.1 - 0.00012 23.0 0.1 0.0003 21.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EON32991.1 - 0.00018 21.4 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EON32991.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EON32991.1 - 0.002 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.17 EON32991.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.12 EON32991.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Dimerisation2 PF16864.5 EON32991.1 - 0.043 13.8 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Met_10 PF02475.16 EON32991.1 - 0.051 13.3 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_9 PF08003.11 EON32991.1 - 0.062 12.2 0.0 0.13 11.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) CMAS PF02353.20 EON32991.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glycos_transf_2 PF00535.26 EON32992.1 - 2e-16 60.3 0.0 2.9e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32992.1 - 2.2e-06 27.8 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PUA PF01472.20 EON32992.1 - 0.13 12.2 0.2 7.2 6.7 0.0 2.3 2 0 0 2 2 2 0 PUA domain Glycos_transf_2 PF00535.26 EON32994.1 - 3.9e-23 82.1 0.1 5.7e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON32994.1 - 1.3e-19 71.0 0.3 2.4e-19 70.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON32994.1 - 8e-09 35.4 0.0 0.00033 20.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EON32994.1 - 2e-05 24.1 0.2 8.5e-05 22.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EON32994.1 - 0.021 14.7 4.7 0.061 13.2 4.7 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 tRNA-synt_2d PF01409.20 EON32994.1 - 0.27 10.7 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Glycos_transf_1 PF00534.20 EON32997.1 - 1.7e-32 112.3 0.0 2.4e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON32997.1 - 2.6e-26 92.6 0.1 5.3e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EON32997.1 - 1.9e-12 47.4 0.0 3.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON32997.1 - 4e-09 36.7 1.9 9.3e-09 35.5 1.9 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON32997.1 - 0.0016 18.9 13.6 0.0016 18.9 13.6 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Hydrolase_4 PF12146.8 EON32998.1 - 4.4e-06 26.1 0.1 4.8e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_trans_1_4 PF13692.6 EON32999.1 - 7.9e-12 45.8 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON32999.1 - 6e-10 39.8 4.7 6e-10 39.8 4.7 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EON32999.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON32999.1 - 1.3e-05 25.3 1.2 2.1e-05 24.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_hydro_16 PF00722.21 EON33000.1 - 5e-16 58.7 0.0 6.6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 EON33000.1 - 0.00039 20.6 0.2 0.031 14.4 0.0 2.3 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 EON33000.1 - 0.11 12.6 0.1 0.52 10.4 0.1 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) 2_5_RNA_ligase2 PF13563.6 EON33001.1 - 6e-10 39.2 0.1 7.9e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EON33001.1 - 0.01 16.0 0.1 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 LigT like Phosphoesterase bPH_6 PF10756.9 EON33001.1 - 0.71 10.0 6.8 0.32 11.1 0.8 2.7 2 1 1 3 3 3 0 Bacterial PH domain S1 PF00575.23 EON33002.1 - 4.6e-81 267.2 28.4 2e-25 88.9 1.9 4.1 4 0 0 4 4 4 4 S1 RNA binding domain DUF2110 PF09883.9 EON33002.1 - 6.3e-07 29.2 1.4 0.16 11.6 0.1 3.3 3 0 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2110) S1_2 PF13509.6 EON33002.1 - 9.8e-07 28.8 5.9 0.015 15.4 0.0 4.9 4 2 0 4 4 4 2 S1 domain RNase_II_C_S1 PF18614.1 EON33002.1 - 0.027 14.4 6.3 0.41 10.6 0.7 3.4 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain EFTUD2 PF16004.5 EON33002.1 - 2.4 8.8 6.2 0.22 12.1 1.3 1.9 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SWIM PF04434.17 EON33003.1 - 4.1e-06 26.3 0.9 6.5e-06 25.7 0.9 1.3 1 0 0 1 1 1 1 SWIM zinc finger SNF2_N PF00176.23 EON33004.1 - 3e-51 174.2 0.0 1e-50 172.4 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EON33004.1 - 5.8e-15 55.6 0.0 9.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TetR_C_1 PF02909.17 EON33005.1 - 8e-15 54.9 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON33005.1 - 3.2e-07 30.0 0.0 7.1e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Put_DNA-bind_N PF06971.13 EON33005.1 - 0.14 12.2 0.1 8 6.6 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus PQQ_3 PF13570.6 EON33006.1 - 0.03 14.8 7.9 29 5.3 0.0 5.8 6 0 0 6 6 6 0 PQQ-like domain TetR_N PF00440.23 EON33007.1 - 4.1e-19 68.1 0.0 7.9e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF295 PF03478.18 EON33007.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF295) HTH_Tnp_1_2 PF13022.6 EON33007.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Hydrolase_4 PF12146.8 EON33008.1 - 8e-14 51.5 4.5 1.2e-12 47.7 4.5 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON33008.1 - 2e-12 48.2 12.2 2.5e-12 47.9 12.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EON33008.1 - 1.3e-08 34.7 0.4 1.1e-05 25.1 0.1 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EON33008.1 - 1.4e-08 34.7 0.2 3.1e-08 33.6 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EON33008.1 - 7.2e-08 31.5 0.4 0.00037 19.3 0.1 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EON33008.1 - 2.2e-06 27.5 0.7 2.2e-06 27.5 0.7 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EON33008.1 - 6.8e-05 22.4 0.7 0.0027 17.2 0.4 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.11 EON33008.1 - 0.0012 17.7 0.0 0.0066 15.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) PAF-AH_p_II PF03403.13 EON33008.1 - 0.011 14.3 0.2 0.36 9.3 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 EON33008.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HTH_18 PF12833.7 EON33008.1 - 0.061 13.6 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short PF00106.25 EON33009.1 - 1.6e-43 148.5 0.0 2.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON33009.1 - 3.5e-29 102.0 0.0 4.4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON33009.1 - 4.2e-13 49.6 0.1 5.6e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON33009.1 - 1.5e-07 31.5 0.1 2.2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON33009.1 - 8.4e-07 28.7 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON33009.1 - 0.0059 16.2 0.1 0.033 13.7 0.3 2.1 2 1 1 3 3 3 1 NmrA-like family ApbA PF02558.16 EON33009.1 - 0.0077 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glyco_trans_4_4 PF13579.6 EON33009.1 - 0.014 15.8 0.5 0.28 11.6 0.3 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EON33009.1 - 0.033 14.2 0.1 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 TrkA_N PF02254.18 EON33009.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 EON33009.1 - 0.17 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CoaE PF01121.20 EON33010.1 - 1.2e-57 194.5 0.5 2.5e-57 193.4 0.0 1.6 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_33 PF13671.6 EON33010.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON33010.1 - 0.0049 17.4 0.0 0.017 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF1326 PF07040.11 EON33010.1 - 0.014 15.5 0.2 0.021 14.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) AAA_28 PF13521.6 EON33010.1 - 0.018 15.3 0.2 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF402 PF04167.13 EON33012.1 - 1.9e-14 53.6 0.3 3.5e-14 52.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF402) SirB PF04247.12 EON33013.1 - 3.3 7.8 9.9 5.2 7.2 7.9 2.3 1 1 1 2 2 2 0 Invasion gene expression up-regulator, SirB UvrB_inter PF17757.1 EON33014.1 - 4.2e-33 113.4 0.1 1.7e-32 111.5 0.0 2.0 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 EON33014.1 - 2.1e-22 78.7 2.3 4.9e-22 77.5 2.3 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 EON33014.1 - 7.6e-19 68.1 0.1 1.6e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON33014.1 - 1.1e-09 38.5 0.0 6.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 EON33014.1 - 2.6e-07 30.2 1.0 1e-06 28.3 1.0 2.2 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 EON33014.1 - 2.2e-05 24.3 0.0 0.00038 20.3 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EON33014.1 - 0.00014 22.2 0.0 0.1 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON33014.1 - 0.00069 19.9 0.1 0.061 13.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EON33014.1 - 0.0011 18.7 0.0 0.062 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EON33014.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_5 PF07728.14 EON33014.1 - 0.0074 16.3 0.0 0.15 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AIG1 PF04548.16 EON33014.1 - 0.013 14.8 0.1 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 AIG1 family UB2H PF14814.6 EON33014.1 - 0.016 15.2 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain ABC_tran PF00005.27 EON33014.1 - 0.017 15.7 0.0 0.84 10.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EON33014.1 - 0.029 14.8 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain UvrD-helicase PF00580.21 EON33014.1 - 0.05 13.1 0.2 1.1 8.7 0.2 2.4 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 EON33014.1 - 0.056 13.5 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 EON33014.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EON33014.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EON33014.1 - 0.1 11.5 0.0 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ZapA PF05164.13 EON33014.1 - 0.61 10.6 7.1 4.5 7.8 0.1 3.9 3 0 0 3 3 3 0 Cell division protein ZapA FtsK_SpoIIIE PF01580.18 EON33014.1 - 1.2 8.4 4.5 12 5.2 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Usp PF00582.26 EON33015.1 - 1.2e-25 90.7 2.2 1.3e-25 90.5 2.2 1.0 1 0 0 1 1 1 1 Universal stress protein family Methyltransf_25 PF13649.6 EON33015.1 - 0.013 16.2 0.1 0.092 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain HMGL-like PF00682.19 EON33016.1 - 3e-39 135.2 0.1 3.4e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 HMGL-like Condensation PF00668.20 EON33017.1 - 2.2e-189 629.9 0.0 1.4e-77 261.3 0.0 3.5 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 EON33017.1 - 2.4e-170 566.7 0.0 2.9e-84 283.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EON33017.1 - 2.2e-26 92.7 10.5 1.1e-12 48.8 0.9 3.6 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EON33017.1 - 9e-23 80.4 2.2 6.9e-13 48.8 0.0 3.8 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding PF00501.28 EON33018.1 - 3e-257 853.0 7.4 2e-92 310.0 0.1 3.5 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.20 EON33018.1 - 2.9e-230 764.7 0.0 8.3e-77 258.8 0.0 4.3 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EON33018.1 - 1.2e-41 140.9 4.6 1.4e-14 54.2 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON33018.1 - 1.6e-21 77.1 1.2 6.7e-07 30.2 0.3 5.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Alpha-amylase PF00128.24 EON33019.1 - 6.8e-17 62.0 0.0 3e-14 53.3 0.0 2.9 2 1 1 3 3 3 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 EON33019.1 - 1e-10 41.8 0.1 4.8e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) MlaE PF02405.16 EON33020.1 - 1e-64 218.1 22.2 1.3e-64 217.8 22.2 1.1 1 0 0 1 1 1 1 Permease MlaE Bac_export_2 PF01312.19 EON33020.1 - 0.51 9.5 7.3 1.7 7.8 5.1 2.4 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family PRA1 PF03208.19 EON33020.1 - 2.2 7.9 14.0 0.25 11.0 0.3 3.0 2 1 1 3 3 3 0 PRA1 family protein MlaE PF02405.16 EON33021.1 - 4.1e-52 176.9 23.1 4.1e-52 176.9 23.1 1.5 1 1 1 2 2 2 1 Permease MlaE Mce4_CUP1 PF11887.8 EON33022.1 - 7.1e-21 74.8 0.1 1.6e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 EON33022.1 - 1.5e-10 41.2 0.3 2.9e-10 40.3 0.3 1.5 1 0 0 1 1 1 1 MlaD protein YajC PF02699.15 EON33022.1 - 0.081 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit MlaD PF02470.20 EON33023.1 - 1.4e-18 67.0 1.2 2.2e-18 66.3 0.4 1.7 2 0 0 2 2 2 1 MlaD protein Mce4_CUP1 PF11887.8 EON33023.1 - 0.0031 17.0 0.4 0.0071 15.8 0.2 1.6 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative YajC PF02699.15 EON33023.1 - 0.14 12.0 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit MlaD PF02470.20 EON33024.1 - 7.7e-17 61.4 0.6 7.7e-17 61.4 0.6 1.9 2 0 0 2 2 2 1 MlaD protein Nsp1_C PF05064.13 EON33024.1 - 0.0045 16.8 0.1 0.0091 15.8 0.1 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF4006 PF13179.6 EON33024.1 - 0.041 13.8 0.2 0.097 12.6 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF1664 PF07889.12 EON33024.1 - 0.14 12.2 1.6 3.5 7.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mce4_CUP1 PF11887.8 EON33024.1 - 0.21 11.0 4.8 2.5 7.5 1.1 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative PhaP_Bmeg PF09602.10 EON33024.1 - 0.28 11.1 0.9 0.74 9.7 0.9 1.7 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) MlaD PF02470.20 EON33025.1 - 6.9e-16 58.3 1.4 1.2e-15 57.6 0.5 1.9 2 0 0 2 2 2 1 MlaD protein DASH_Duo1 PF08651.10 EON33025.1 - 0.025 14.4 0.6 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 Mce4_CUP1 PF11887.8 EON33025.1 - 0.046 13.2 1.5 0.22 10.9 1.6 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative NPV_P10 PF05531.12 EON33025.1 - 0.13 12.7 0.8 25 5.4 0.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MlaD PF02470.20 EON33026.1 - 1.2e-11 44.7 0.1 2.9e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON33026.1 - 9.3e-05 22.0 1.0 0.00013 21.6 1.0 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative TelA PF05816.11 EON33026.1 - 0.0089 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DASH_Duo1 PF08651.10 EON33026.1 - 0.064 13.0 0.5 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF1664 PF07889.12 EON33026.1 - 0.13 12.3 0.1 3.8 7.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1495 PF07381.11 EON33026.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) DUF948 PF06103.11 EON33026.1 - 0.24 11.7 2.4 12 6.2 0.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EON33026.1 - 1 9.4 11.7 1.3 9.1 3.7 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MlaD PF02470.20 EON33027.1 - 4.3e-11 43.0 0.4 8.9e-11 41.9 0.4 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON33027.1 - 0.044 13.2 1.0 0.071 12.6 1.0 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3828 PF12883.7 EON33028.1 - 0.016 15.5 0.1 0.052 13.9 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3828) GspL_C PF12693.7 EON33028.1 - 0.02 14.7 0.2 0.037 13.9 0.2 1.4 1 0 0 1 1 1 0 GspL periplasmic domain Alpha-amylase PF00128.24 EON33029.1 - 1e-17 64.8 0.0 4.9e-13 49.4 0.0 3.4 3 0 0 3 3 3 3 Alpha amylase, catalytic domain CBM_48 PF02922.18 EON33030.1 - 1.1e-18 67.3 0.0 2.1e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EON33030.1 - 1.5e-16 60.9 0.0 1.1e-13 51.5 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL5 PF14872.6 EON33030.1 - 0.075 11.1 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Acyl_transf_3 PF01757.22 EON33031.1 - 9.3e-16 57.8 36.5 2.7e-15 56.3 36.5 1.8 1 1 0 1 1 1 1 Acyltransferase family TetR_N PF00440.23 EON33032.1 - 2.5e-12 46.4 0.0 5.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 EON33032.1 - 8.5e-08 32.1 0.2 6.1e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Aminotran_3 PF00202.21 EON33033.1 - 1.2e-117 393.0 0.0 1.4e-117 392.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EON33033.1 - 0.0033 16.7 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EON33034.1 - 5.5e-52 177.1 0.0 6.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EON33034.1 - 2.5e-08 33.7 0.7 3.7e-08 33.1 0.7 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EON33034.1 - 1.9e-06 26.7 0.0 2.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EON33034.1 - 2.2e-05 23.9 0.2 4.2e-05 23.0 0.2 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EON33034.1 - 5.5e-05 22.3 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Amidohydro_2 PF04909.14 EON33034.1 - 0.0011 18.9 0.5 0.0011 18.9 0.5 2.0 2 0 0 2 2 2 1 Amidohydrolase NAD_binding_3 PF03447.16 EON33034.1 - 0.034 14.8 0.3 0.088 13.5 0.3 1.8 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Thi4 PF01946.17 EON33034.1 - 0.37 10.0 3.3 0.33 10.1 0.4 2.3 3 0 0 3 3 3 0 Thi4 family NHL PF01436.21 EON33034.1 - 0.54 10.4 2.1 3.5 7.9 0.0 3.0 3 0 0 3 3 3 0 NHL repeat AAA_26 PF13500.6 EON33035.1 - 5.3e-29 101.5 0.0 6.6e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain DUF1611 PF07755.11 EON33035.1 - 0.00089 18.6 5.8 0.24 10.6 0.3 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF1611_C) P-loop domain CbiA PF01656.23 EON33035.1 - 0.006 16.6 0.2 0.024 14.7 0.2 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Radical_SAM PF04055.21 EON33036.1 - 5.5e-15 56.1 0.1 1.2e-14 55.0 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.13 EON33036.1 - 2.2e-11 43.8 0.0 5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain zf-NADH-PPase PF09297.11 EON33037.1 - 0.0038 16.8 4.8 0.0099 15.5 4.8 1.7 1 1 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EON33037.1 - 0.031 14.2 0.5 0.058 13.3 0.5 1.6 1 0 0 1 1 1 0 Nudix N-terminal Zn_ribbon_recom PF13408.6 EON33037.1 - 0.05 14.1 0.8 0.074 13.6 0.8 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LapA_dom PF06305.11 EON33038.1 - 0.017 14.9 0.3 0.019 14.8 0.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2749 PF10907.8 EON33038.1 - 0.073 13.2 1.0 0.09 13.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Herpes_gE PF02480.16 EON33038.1 - 0.09 11.5 0.4 0.087 11.6 0.4 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PhoR PF11808.8 EON33038.1 - 0.18 12.2 0.7 0.29 11.6 0.7 1.3 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Vpu PF00558.19 EON33038.1 - 0.22 11.3 0.1 0.25 11.1 0.1 1.1 1 0 0 1 1 1 0 Vpu protein DUF2567 PF10821.8 EON33039.1 - 4e-18 66.0 7.1 5.1e-18 65.7 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) NUDIX PF00293.28 EON33040.1 - 0.00015 21.8 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_M24 PF00557.24 EON33041.1 - 6.8e-41 140.3 0.0 7.8e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 HTH_31 PF13560.6 EON33042.1 - 1.8e-11 44.2 1.6 3.1e-11 43.4 1.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EON33042.1 - 1.4e-09 37.9 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 EON33042.1 - 1.6e-06 28.5 0.0 2.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 EON33042.1 - 2.5e-06 27.4 0.0 4.8e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 EON33042.1 - 0.014 15.2 0.2 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 MerR family regulatory protein HTH_25 PF13413.6 EON33042.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain CMD PF02627.20 EON33042.1 - 0.065 13.3 0.5 6.9 6.8 0.1 2.9 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family Clp_N PF02861.20 EON33042.1 - 0.13 12.4 2.2 8.6 6.6 0.3 2.3 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component DUF1990 PF09348.10 EON33043.1 - 7.1e-53 178.8 0.2 7.9e-53 178.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) NadA PF02445.16 EON33044.1 - 5.4e-110 367.3 0.0 6.1e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein SUV3_C PF12513.8 EON33044.1 - 0.18 11.8 0.6 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal QRPTase_C PF01729.19 EON33045.1 - 1.8e-56 190.6 0.0 2.6e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EON33045.1 - 9.9e-25 86.4 0.1 3.2e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Histidinol_dh PF00815.20 EON33047.1 - 5.8e-150 499.8 3.3 6.6e-150 499.7 3.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Aminotran_1_2 PF00155.21 EON33048.1 - 3.7e-48 164.5 0.0 5e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EON33048.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Allinase IGPD PF00475.18 EON33049.1 - 7e-58 195.0 0.2 8.9e-58 194.7 0.2 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase GATase PF00117.28 EON33050.1 - 6e-16 58.8 0.0 7.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EON33050.1 - 0.00071 19.2 0.0 0.00098 18.8 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EON33050.1 - 0.034 13.9 0.4 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Peptidase C26 DJ-1_PfpI PF01965.24 EON33050.1 - 0.12 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family SNO PF01174.19 EON33050.1 - 0.19 11.6 0.0 14 5.5 0.0 2.1 2 0 0 2 2 2 0 SNO glutamine amidotransferase family DUF3487 PF11990.8 EON33051.1 - 0.014 15.2 1.1 0.018 14.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF2207 PF09972.9 EON33051.1 - 1.6 7.4 4.4 1.8 7.2 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4231 PF14015.6 EON33051.1 - 3.1 8.3 4.8 4 8.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Phage_holin_3_6 PF07332.11 EON33051.1 - 3.1 7.9 12.3 3.8 7.6 12.3 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III His_biosynth PF00977.21 EON33052.1 - 1.5e-60 204.6 0.9 1.6e-60 204.4 0.9 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EON33052.1 - 0.00023 20.7 6.9 0.02 14.3 0.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.17 EON33052.1 - 0.035 13.2 0.1 1.6 7.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) IMPDH PF00478.25 EON33052.1 - 0.1 11.6 3.1 0.93 8.4 0.1 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Inositol_P PF00459.25 EON33053.1 - 1.6e-38 132.8 0.0 2e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family His_biosynth PF00977.21 EON33054.1 - 1.1e-89 299.9 0.3 1.2e-89 299.7 0.3 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EON33054.1 - 4.2e-10 39.5 8.0 9.3e-05 22.0 0.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 EON33054.1 - 7.1e-09 35.3 3.2 0.00055 19.3 0.8 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EON33054.1 - 1e-07 31.4 0.1 0.00058 19.0 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EON33054.1 - 7e-07 28.7 0.5 0.014 14.7 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EON33054.1 - 7.7e-07 28.7 0.6 0.00082 18.8 0.1 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 EON33054.1 - 1.6e-05 24.1 3.6 0.019 14.0 0.9 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 EON33054.1 - 8.6e-05 21.9 0.2 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase FMN_dh PF01070.18 EON33054.1 - 0.0035 16.4 7.7 0.059 12.4 2.2 2.4 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 EON33054.1 - 0.028 13.9 0.2 0.076 12.5 0.0 1.7 2 0 0 2 2 2 0 PcrB family Glu_synthase PF01645.17 EON33054.1 - 0.063 12.4 0.8 0.45 9.6 0.1 2.0 2 0 0 2 2 2 0 Conserved region in glutamate synthase Trp_syntA PF00290.20 EON33054.1 - 0.2 10.5 1.0 0.32 9.8 0.1 1.7 2 0 0 2 2 2 0 Tryptophan synthase alpha chain PRA-CH PF01502.18 EON33055.1 - 8.3e-33 112.1 0.8 1.2e-32 111.6 0.8 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Tautomerase PF01361.21 EON33056.1 - 1.6e-15 56.7 0.0 1.8e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 EON33056.1 - 1.9e-06 27.8 0.0 2.1e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Chorismate_bind PF00425.18 EON33057.1 - 6.3e-93 311.0 0.0 8.7e-93 310.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EON33057.1 - 5.5e-32 110.9 0.0 5.3e-31 107.7 0.0 2.5 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Trp_oprn_chp PF09534.10 EON33058.1 - 9.2e-49 165.7 18.0 1.4e-48 165.1 18.0 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_3_6 PF07332.11 EON33058.1 - 0.0025 17.9 18.0 0.013 15.6 6.3 2.2 1 1 1 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III MSA-2c PF12238.8 EON33058.1 - 0.03 14.3 1.4 0.041 13.9 1.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2173 PF09941.9 EON33058.1 - 0.21 11.9 2.4 0.4 11.0 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2173) IGPS PF00218.21 EON33059.1 - 5.2e-81 271.5 0.1 5.9e-81 271.4 0.1 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase OMPdecase PF00215.24 EON33059.1 - 3.2e-06 26.9 0.3 4.1e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family FMN_dh PF01070.18 EON33059.1 - 8.2e-05 21.8 2.9 0.0007 18.7 2.8 2.1 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EON33059.1 - 0.0013 18.2 1.6 0.47 9.9 0.0 3.1 2 1 0 3 3 3 1 Histidine biosynthesis protein QRPTase_C PF01729.19 EON33059.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PALP PF00291.25 EON33060.1 - 3.6e-51 174.3 2.6 4.3e-51 174.1 2.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Gmad2 PF10648.9 EON33060.1 - 0.071 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Trp_syntA PF00290.20 EON33061.1 - 2.8e-72 242.7 0.0 3e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PcrB PF01884.17 EON33061.1 - 0.0002 20.9 0.1 0.00035 20.1 0.1 1.3 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 EON33061.1 - 0.0008 18.9 0.1 0.0028 17.2 0.1 1.8 1 1 1 2 2 2 1 Histidine biosynthesis protein BtpA PF03437.15 EON33061.1 - 0.03 13.8 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 BtpA family HMGL-like PF00682.19 EON33061.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 HMGL-like LGT PF01790.18 EON33062.1 - 1.7e-62 210.8 8.4 2.1e-62 210.5 8.4 1.1 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase ODV-E18 PF10717.9 EON33062.1 - 0.11 12.4 0.3 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 GATase_2 PF00310.21 EON33063.1 - 2.2e-162 540.6 0.0 2.8e-162 540.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EON33063.1 - 2.9e-149 497.2 0.0 6e-146 486.3 0.0 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EON33063.1 - 3.5e-110 367.9 0.0 5e-110 367.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 EON33063.1 - 1.6e-79 265.9 0.6 2.6e-79 265.3 0.6 1.3 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 EON33063.1 - 0.094 11.7 7.1 0.0079 15.3 1.6 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pyr_redox_2 PF07992.14 EON33064.1 - 6e-27 94.6 0.1 8.9e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EON33064.1 - 1.8e-18 66.3 0.1 2.9e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EON33064.1 - 1e-10 41.7 2.3 5.3e-10 39.4 0.1 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EON33064.1 - 1.6e-09 37.6 3.9 2.1e-09 37.2 0.2 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EON33064.1 - 6.1e-09 36.3 1.6 0.00021 21.8 0.0 3.5 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON33064.1 - 8.2e-07 28.7 0.7 3.6e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EON33064.1 - 3.9e-06 27.2 0.1 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.24 EON33064.1 - 6.5e-06 26.0 6.1 0.0001 22.0 0.1 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EON33064.1 - 8.7e-06 25.2 0.1 0.023 13.9 0.0 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON33064.1 - 9.6e-06 24.5 0.2 0.00027 19.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EON33064.1 - 2e-05 24.0 0.1 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EON33064.1 - 8.1e-05 22.0 0.1 8.1e-05 22.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EON33064.1 - 0.00015 21.0 0.2 0.00015 21.0 0.2 2.7 3 1 1 4 4 4 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EON33064.1 - 0.00041 19.8 0.0 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 EON33064.1 - 0.0013 18.6 0.2 0.077 12.9 0.0 2.3 2 0 0 2 2 2 1 YjeF-related protein N-terminus AdoHcyase_NAD PF00670.21 EON33064.1 - 0.0027 17.8 0.6 0.75 9.8 0.1 2.4 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.22 EON33064.1 - 0.0045 16.1 1.9 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 EON33064.1 - 0.0091 15.9 0.3 0.019 14.9 0.0 1.7 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 EON33064.1 - 0.015 13.7 0.0 0.18 10.2 0.0 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 EON33064.1 - 0.028 13.6 0.1 0.028 13.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 EON33064.1 - 0.033 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EON33064.1 - 0.04 14.5 0.7 0.69 10.5 0.0 2.5 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 EON33064.1 - 0.055 13.3 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.18 EON33064.1 - 0.057 13.7 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.15 EON33064.1 - 0.085 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase K_oxygenase PF13434.6 EON33064.1 - 0.099 11.8 0.1 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 EON33064.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 EON33064.1 - 0.16 11.0 1.3 0.21 10.6 0.1 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.20 EON33064.1 - 0.22 11.6 0.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EON33064.1 - 0.44 10.5 0.0 0.44 10.5 0.0 2.2 2 1 0 3 3 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EON33064.1 - 1.1 8.0 2.2 0.74 8.6 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase PK PF00224.21 EON33065.1 - 9.9e-125 416.0 1.7 1.3e-124 415.6 1.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EON33065.1 - 2.8e-24 85.6 0.1 1.5e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EON33065.1 - 0.00014 21.1 3.3 0.0011 18.2 2.0 2.4 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EON33065.1 - 0.0064 15.5 1.6 0.021 13.8 0.0 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.17 EON33065.1 - 0.15 11.5 0.5 0.93 8.9 0.1 2.3 2 1 0 3 3 3 0 PcrB family 4HBT_3 PF13622.6 EON33066.1 - 7.7e-53 180.3 2.3 9.2e-53 180.0 2.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EON33066.1 - 1.1e-43 148.3 0.1 2.2e-36 124.6 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Acetyltransf_3 PF13302.7 EON33068.1 - 2.6e-45 154.5 0.2 1.2e-22 81.1 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON33068.1 - 3.5e-15 56.3 0.0 8.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EON33068.1 - 0.00018 21.7 0.0 0.0059 16.8 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EON33068.1 - 0.00058 19.6 1.8 0.074 12.7 0.0 2.9 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON33068.1 - 0.0049 17.3 0.1 0.48 10.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EON33068.1 - 0.035 14.3 1.4 0.062 13.4 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NDUF_B4 PF07225.12 EON33068.1 - 0.17 11.8 0.5 11 5.9 0.2 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) FAD_binding_6 PF00970.24 EON33069.1 - 2.1e-11 44.0 0.0 5.4e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 EON33069.1 - 7.3e-09 35.5 1.5 1.2e-08 34.8 1.5 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON33069.1 - 1.5e-07 32.0 0.0 3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON33069.1 - 0.0066 16.6 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF2170 PF09938.9 EON33070.1 - 0.061 13.0 0.0 0.56 9.9 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2170) Phage_TAC_7 PF10109.9 EON33070.1 - 0.15 12.2 1.1 0.32 11.1 0.2 2.0 2 1 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 WES_acyltransf PF03007.16 EON33071.1 - 2.3e-59 201.3 0.1 3.2e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON33071.1 - 2e-11 44.0 0.0 3.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Collagen_mid PF15984.5 EON33071.1 - 0.022 14.5 0.2 0.034 13.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial collagen, middle region SecA_DEAD PF07517.14 EON33073.1 - 2.4e-126 420.9 0.4 4e-126 420.2 0.4 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 EON33073.1 - 5.1e-68 229.1 3.8 1.1e-67 228.0 3.8 1.6 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EON33073.1 - 5.6e-35 120.4 0.1 1.5e-34 119.0 0.1 1.8 1 0 0 1 1 1 1 SecA preprotein cross-linking domain CutC PF03932.14 EON33073.1 - 0.0017 17.8 0.0 0.14 11.6 0.0 2.6 3 0 0 3 3 3 1 CutC family DEAD PF00270.29 EON33073.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4497 PF14924.6 EON33073.1 - 0.19 12.2 0.0 0.48 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Helicase_C PF00271.31 EON33073.1 - 0.2 12.0 0.7 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Ribosom_S30AE_C PF16321.5 EON33074.1 - 1.8e-23 82.0 0.2 4.2e-23 80.8 0.2 1.6 2 0 0 2 2 2 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 EON33074.1 - 8.3e-20 71.4 0.3 1.7e-19 70.4 0.1 1.6 2 0 0 2 2 2 1 Sigma 54 modulation protein / S30EA ribosomal protein UPRTase PF14681.6 EON33075.1 - 0.00019 20.9 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EON33075.1 - 0.00036 20.1 0.2 0.00045 19.8 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AvrD PF05655.11 EON33075.1 - 0.05 12.9 0.5 0.07 12.4 0.5 1.1 1 0 0 1 1 1 0 Pseudomonas avirulence D protein (AvrD) PRTase_2 PF15609.6 EON33075.1 - 0.052 13.1 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Gmad1 PF10647.9 EON33076.1 - 1.5e-54 185.4 18.2 2.6e-54 184.6 18.2 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Germane PF10646.9 EON33076.1 - 2.5e-10 41.1 0.0 2.5e-09 37.8 0.0 2.7 4 1 0 4 4 4 1 Sporulation and spore germination HATPase_c PF02518.26 EON33077.1 - 4e-20 72.4 0.0 8.6e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON33077.1 - 3.4e-15 55.8 0.5 3.4e-15 55.8 0.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EON33077.1 - 1.8e-08 34.6 0.4 1.8e-08 34.6 0.4 2.8 4 0 0 4 4 4 1 HAMP domain HATPase_c_2 PF13581.6 EON33077.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 EON33078.1 - 1e-27 96.5 0.1 1.7e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EON33078.1 - 5.6e-26 90.4 0.4 2.3e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EON33078.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Thymidylate_kin PF02223.17 EON33079.1 - 6.2e-23 81.4 0.0 8.3e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EON33079.1 - 5.9e-05 23.4 2.3 0.00013 22.3 2.4 1.4 1 1 1 2 2 2 1 AAA domain T3SSipB PF16535.5 EON33079.1 - 0.0022 18.5 0.0 0.0032 18.0 0.0 1.2 1 0 0 1 1 1 1 Type III cell invasion protein SipB AAA_18 PF13238.6 EON33079.1 - 0.0034 17.9 0.0 0.021 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON33079.1 - 0.0039 17.4 2.1 0.032 14.4 2.1 2.2 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EON33079.1 - 0.0077 16.1 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_30 PF13604.6 EON33079.1 - 0.047 13.4 1.3 0.32 10.7 0.5 2.5 2 2 1 3 3 3 0 AAA domain MobB PF03205.14 EON33079.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EON33079.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF463 PF04317.12 EON33079.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 DUF1523 PF07509.11 EON33079.1 - 0.21 10.9 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1523) DUF3357 PF11837.8 EON33080.1 - 0.46 11.0 4.0 2.4 8.6 0.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) AdoHcyase PF05221.17 EON33081.1 - 1.4e-146 487.3 0.0 1.6e-146 487.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EON33081.1 - 1.8e-78 262.2 2.4 2.6e-78 261.7 2.4 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EON33081.1 - 5.8e-08 32.3 0.2 1e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EON33081.1 - 2.1e-06 27.4 0.2 3.7e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EON33081.1 - 0.00017 22.0 0.1 0.00043 20.7 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 EON33081.1 - 0.00099 19.4 0.4 0.0049 17.1 0.4 2.2 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EON33081.1 - 0.0011 19.0 0.1 0.0025 17.9 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EON33081.1 - 0.027 14.3 0.4 0.095 12.6 0.1 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON33081.1 - 0.046 14.3 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MaAIMP_sms PF16951.5 EON33082.1 - 4.5e-09 35.9 0.4 5.7e-09 35.6 0.4 1.2 1 0 0 1 1 1 1 Putative methionine and alanine importer, small subunit DUF2427 PF10348.9 EON33082.1 - 0.022 14.5 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Pilin_N PF07790.11 EON33082.1 - 0.089 13.7 0.5 0.094 13.6 0.5 1.1 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal SNF PF00209.18 EON33083.1 - 4.3e-104 349.1 39.6 3.5e-67 227.3 24.2 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family WXG100 PF06013.12 EON33084.1 - 1.6e-10 41.1 2.1 1.8e-10 40.9 2.1 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF3772 PF12607.8 EON33084.1 - 0.082 12.7 3.6 0.14 11.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) WXG100 PF06013.12 EON33085.1 - 2.9e-13 49.9 2.3 3.2e-13 49.7 2.3 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 EON33085.1 - 0.025 15.0 4.4 0.029 14.8 4.4 1.1 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm SGT1 PF07093.11 EON33085.1 - 0.14 10.6 0.0 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 SGT1 protein ESX-1_EspG PF14011.6 EON33086.1 - 6.6e-53 179.8 14.7 8.1e-53 179.5 14.7 1.0 1 0 0 1 1 1 1 EspG family Minor_tail_Z PF06763.11 EON33086.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) PPE PF00823.19 EON33087.1 - 9.5e-20 71.3 22.1 9.5e-20 71.3 22.1 1.7 2 0 0 2 2 2 1 PPE family PE PF00934.20 EON33088.1 - 2.8e-16 59.6 8.7 3.4e-16 59.3 8.7 1.0 1 0 0 1 1 1 1 PE family T7SS_ESX_EspC PF10824.8 EON33088.1 - 1.3e-05 25.6 6.1 1.5e-05 25.4 6.1 1.1 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm WXG100 PF06013.12 EON33088.1 - 0.011 16.0 0.7 0.022 15.0 0.7 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG EccE PF11203.8 EON33088.1 - 0.16 12.3 4.0 0.27 11.6 3.9 1.5 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE EspB_PE PF18625.1 EON33088.1 - 0.31 11.5 6.9 1.1 9.7 6.9 1.9 1 1 0 1 1 1 0 ESX-1 secreted protein B PE domain Sde2_N_Ubi PF13019.6 EON33089.1 - 0.18 11.7 0.2 0.32 10.8 0.2 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain T7SS_ESX_EspC PF10824.8 EON33090.1 - 1.3e-07 32.0 8.8 1.5e-07 31.8 8.8 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm YbaB_DNA_bd PF02575.16 EON33091.1 - 4.8e-09 36.3 0.2 6.1e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family YbaB_DNA_bd PF02575.16 EON33092.1 - 0.15 12.3 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family AAA_31 PF13614.6 EON33094.1 - 1.6e-12 47.7 0.0 2.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EON33094.1 - 9.3e-10 38.6 0.0 1.9e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EON33094.1 - 1.9e-05 24.2 0.0 4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EON33094.1 - 0.00025 20.6 0.1 0.00073 19.1 0.1 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_16 PF13191.6 EON33094.1 - 0.0042 17.5 0.0 0.006 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain VirC1 PF07015.11 EON33094.1 - 0.011 15.1 0.5 0.025 13.9 0.2 1.7 1 1 1 2 2 2 0 VirC1 protein DUF2288 PF10052.9 EON33094.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) ArsA_ATPase PF02374.15 EON33094.1 - 0.065 12.4 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Fer4_NifH PF00142.18 EON33094.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family WXG100 PF06013.12 EON33096.1 - 0.002 18.3 0.1 0.027 14.7 0.0 3.1 3 0 0 3 3 3 1 Proteins of 100 residues with WXG DUF4259 PF14078.6 EON33096.1 - 0.14 12.9 3.0 13 6.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) SNARE_assoc PF09335.11 EON33097.1 - 3.4e-21 75.9 8.8 3.8e-21 75.8 6.9 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2878 PF11086.8 EON33097.1 - 0.058 13.6 0.1 0.058 13.6 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2878) NEMP PF10225.9 EON33097.1 - 0.22 11.1 1.9 0.33 10.6 1.9 1.2 1 0 0 1 1 1 0 NEMP family Abhydrolase_1 PF00561.20 EON33098.1 - 7.5e-32 111.0 0.8 8.2e-23 81.4 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON33098.1 - 1.9e-23 84.3 11.4 2.6e-23 83.8 11.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON33098.1 - 3.3e-18 65.8 0.6 9.3e-18 64.4 0.6 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EON33098.1 - 0.0002 21.3 1.4 0.28 11.0 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 EON33098.1 - 0.0042 16.0 0.0 0.0078 15.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 EON33098.1 - 0.0089 15.6 0.1 11 5.5 0.0 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF900 PF05990.12 EON33098.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 EON33098.1 - 0.012 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.10 EON33098.1 - 0.037 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ser_hydrolase PF06821.13 EON33098.1 - 0.097 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase PF07224.11 EON33098.1 - 0.12 11.4 0.1 0.35 9.8 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.13 EON33098.1 - 0.12 12.0 0.3 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EON33098.1 - 0.14 11.9 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EON33098.1 - 0.17 12.0 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 EON33098.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.11 EON33098.1 - 0.31 10.3 0.0 1.3 8.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) TM2 PF05154.16 EON33100.1 - 2.2e-12 47.1 13.9 1.9e-11 44.1 13.9 2.0 1 1 0 1 1 1 1 TM2 domain PT-TG PF14449.6 EON33100.1 - 0.0074 16.2 0.1 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Pre-toxin TG Borrelia_P13 PF05628.12 EON33100.1 - 0.085 12.8 8.1 0.14 12.1 8.1 1.3 1 1 0 1 1 1 0 Borrelia membrane protein P13 PseudoU_synth_1 PF01416.20 EON33101.1 - 5.5e-28 97.6 0.0 5.4e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ribosomal_L17 PF01196.19 EON33102.1 - 6.2e-36 123.2 0.0 1.2e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 UPF0175 PF03683.13 EON33102.1 - 0.0038 16.9 0.0 0.92 9.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0175) RNA_pol_A_CTD PF03118.15 EON33103.1 - 4.8e-27 93.5 0.0 8.5e-27 92.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 EON33103.1 - 1.1e-23 83.7 0.0 3.9e-23 82.0 0.0 1.8 1 1 1 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EON33103.1 - 4.3e-20 70.9 0.0 6.9e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 EON33103.1 - 0.11 12.2 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S4 PF00163.19 EON33104.1 - 7.9e-29 100.4 3.1 1.2e-28 99.8 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EON33104.1 - 8.6e-19 67.0 0.5 1.6e-18 66.1 0.5 1.5 1 0 0 1 1 1 1 S4 domain SHD1 PF03983.12 EON33104.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Acetate_kinase PF00871.17 EON33104.1 - 0.21 10.2 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Acetokinase family Ribosomal_S11 PF00411.19 EON33105.1 - 1.7e-47 160.4 0.5 2.4e-47 159.9 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 ELFV_dehydrog PF00208.21 EON33105.1 - 0.0013 18.5 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L18p PF00861.22 EON33105.1 - 0.093 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S13 PF00416.22 EON33106.1 - 1.9e-35 122.0 3.3 9.3e-34 116.6 3.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EON33106.1 - 0.014 14.2 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L36 PF00444.18 EON33107.1 - 2e-18 66.3 9.2 2.2e-18 66.2 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 eIF-1a PF01176.19 EON33108.1 - 1.1e-28 98.8 0.1 1.2e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF1801 PF08818.11 EON33109.1 - 7.2e-05 23.2 0.0 8.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) Phage_holin_4_2 PF04020.13 EON33110.1 - 8.4e-30 103.5 20.0 9.8e-30 103.3 20.0 1.0 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV TM_helix PF05552.12 EON33110.1 - 0.0043 17.0 0.7 0.0043 17.0 0.7 3.0 3 1 0 3 3 3 1 Conserved TM helix DUF5326 PF17260.2 EON33110.1 - 0.13 12.5 0.5 0.13 12.5 0.5 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5326) Peptidase_U4 PF03419.13 EON33110.1 - 2.3 7.4 11.0 0.057 12.7 2.3 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA SIMPL PF04402.14 EON33111.1 - 1.8e-42 146.1 9.0 2.2e-42 145.8 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Pectate_lyase_3 PF12708.7 EON33111.1 - 0.027 14.3 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 Pectate lyase superfamily protein Tyr_Deacylase PF02580.16 EON33112.1 - 2.9e-49 167.3 0.0 3.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FdhD-NarQ PF02634.15 EON33113.1 - 3.8e-80 269.0 0.1 4.4e-80 268.8 0.1 1.0 1 0 0 1 1 1 1 FdhD/NarQ family DUF2156 PF09924.9 EON33114.1 - 1.5e-76 257.3 0.0 1.9e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Peptidase_M24 PF00557.24 EON33115.1 - 1.1e-40 139.6 0.4 1.2e-40 139.4 0.4 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4949 PF16307.5 EON33115.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) ADK PF00406.22 EON33116.1 - 1e-51 175.0 0.0 1.2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EON33116.1 - 3.9e-31 108.3 0.0 4.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON33116.1 - 1.4e-05 25.3 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EON33116.1 - 5.8e-05 23.7 0.0 0.00014 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EON33116.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase Thymidylate_kin PF02223.17 EON33116.1 - 0.00091 19.0 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.6 EON33116.1 - 0.01 16.1 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EON33116.1 - 0.092 13.2 0.2 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON33116.1 - 0.13 12.2 0.1 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SecY PF00344.20 EON33117.1 - 1.1e-113 379.5 13.9 1.4e-113 379.2 13.9 1.1 1 0 0 1 1 1 1 SecY translocase DUF1467 PF07330.12 EON33117.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) Ribosomal_L27A PF00828.19 EON33118.1 - 1.9e-33 115.9 2.8 2.3e-33 115.6 2.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A LpxI_N PF17930.1 EON33118.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 LpxI N-terminal domain Ribosomal_L18 PF17135.4 EON33118.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L30 PF00327.20 EON33119.1 - 1.1e-16 60.4 1.2 1.2e-16 60.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 EON33120.1 - 3.9e-29 99.9 0.8 5.8e-29 99.4 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EON33120.1 - 7.4e-29 99.5 2.8 1.3e-28 98.7 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L18p PF00861.22 EON33121.1 - 1.7e-45 154.1 4.8 2.2e-45 153.8 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L6 PF00347.23 EON33122.1 - 1.3e-42 144.4 1.4 1.9e-21 76.5 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 OspE PF02471.17 EON33122.1 - 0.099 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein E Ribosomal_S8 PF00410.19 EON33123.1 - 1.4e-49 167.2 0.0 1.6e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 GSDH PF07995.11 EON33124.1 - 6.8e-60 203.1 0.0 8.9e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 EON33124.1 - 0.0054 16.8 0.1 1.6 9.2 0.0 3.5 4 0 0 4 4 4 1 Two component regulator propeller SGL PF08450.12 EON33124.1 - 0.038 13.6 0.1 14 5.2 0.0 3.3 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Cupin_2 PF07883.11 EON33125.1 - 0.00013 21.6 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EON33125.1 - 0.009 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Molybdopterin PF00384.22 EON33126.1 - 3.5e-129 431.5 0.0 4.4e-129 431.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EON33126.1 - 1.9e-16 60.1 0.0 4.8e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EON33126.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain Fer4_11 PF13247.6 EON33127.1 - 6.5e-36 122.5 6.1 6.5e-36 122.5 6.1 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 EON33127.1 - 3e-27 94.1 0.0 5.8e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_10 PF13237.6 EON33127.1 - 9.4e-08 32.1 20.0 1.3e-05 25.2 6.2 3.3 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON33127.1 - 3e-06 27.0 18.5 0.0081 16.2 0.2 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_7 PF12838.7 EON33127.1 - 1e-05 26.0 21.9 0.004 17.7 7.2 3.8 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 EON33127.1 - 0.00014 22.0 18.2 0.0067 16.6 5.7 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 EON33127.1 - 0.0055 16.5 17.7 0.036 13.9 2.2 4.5 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_2 PF12797.7 EON33127.1 - 0.0082 16.2 24.1 0.015 15.4 1.7 4.5 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_15 PF13459.6 EON33127.1 - 0.05 14.4 10.4 0.53 11.1 1.5 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EON33127.1 - 0.098 13.2 6.1 0.42 11.2 0.2 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 EON33127.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.6 2 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 EON33127.1 - 0.22 11.7 22.0 0.093 12.9 1.6 3.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON33127.1 - 0.22 12.1 25.8 0.093 13.3 1.3 4.1 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_17 PF13534.6 EON33127.1 - 1.8 9.2 19.6 0.63 10.6 0.3 3.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Nitrate_red_del PF02613.15 EON33128.1 - 2e-10 40.8 0.1 2.9e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit Bac_luciferase PF00296.20 EON33128.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase SPO11_like PF03533.14 EON33128.1 - 0.1 12.7 0.3 17 5.6 0.0 2.6 2 0 0 2 2 2 0 SPO11 homologue Nitrate_red_gam PF02665.14 EON33129.1 - 1.1e-84 283.4 11.3 1.3e-84 283.2 11.3 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit RHS_repeat PF05593.14 EON33129.1 - 0.057 14.0 0.2 0.22 12.1 0.2 1.9 2 0 0 2 2 2 0 RHS Repeat MFS_1 PF07690.16 EON33130.1 - 8.8e-44 149.8 51.0 8.8e-44 149.8 51.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON33130.1 - 1.3e-08 34.2 32.6 5.7e-08 32.1 13.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EON33130.1 - 0.0015 17.1 39.7 0.036 12.6 11.3 3.4 1 1 2 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 EON33130.1 - 0.11 10.7 0.1 0.11 10.7 0.1 3.7 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Gaa1 PF04114.14 EON33130.1 - 0.13 11.3 1.8 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component DUF5357 PF17310.2 EON33130.1 - 0.29 9.6 1.4 0.59 8.6 1.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5357) COX6C PF02937.15 EON33130.1 - 0.3 11.2 0.9 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF4262 PF14081.6 EON33131.1 - 2.3e-25 89.2 0.0 3.4e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4262) Wzy_C PF04932.15 EON33132.1 - 2.7e-09 36.8 6.5 2.7e-09 36.8 6.5 4.5 3 2 0 3 3 3 1 O-Antigen ligase GHMP_kinases_N PF00288.26 EON33132.1 - 0.66 10.3 13.9 2.4 8.4 0.3 3.6 3 0 0 3 3 3 0 GHMP kinases N terminal domain Glycos_transf_1 PF00534.20 EON33133.1 - 1.9e-20 73.1 0.0 2.6e-19 69.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON33133.1 - 2.7e-16 60.2 0.4 2.1e-15 57.4 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EON33133.1 - 2.7e-08 34.1 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON33133.1 - 2.1e-05 24.6 0.6 4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON33133.1 - 0.00016 22.2 0.7 0.00016 22.2 0.7 3.0 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain PEP-utilizers PF00391.23 EON33133.1 - 0.1 12.3 3.1 0.58 9.9 0.1 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain Polysacc_synt PF01943.17 EON33134.1 - 2e-20 73.3 16.0 2e-20 73.3 16.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 EON33134.1 - 3.4e-18 65.9 12.7 3.4e-18 65.9 12.7 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 EON33134.1 - 1.5e-11 44.5 20.3 1.5e-11 44.5 20.3 3.9 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Glycos_transf_1 PF00534.20 EON33135.1 - 1.8e-26 92.7 0.0 3.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON33135.1 - 1.6e-22 80.4 0.2 4.2e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON33135.1 - 8.1e-10 38.9 5.7 1.2e-06 28.6 3.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EON33135.1 - 2.2e-07 31.2 0.0 4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 EON33135.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Cellulase PF00150.18 EON33136.1 - 6.6e-07 29.0 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_10 PF00331.20 EON33136.1 - 0.00087 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EON33136.1 - 0.02 14.2 0.2 0.57 9.5 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase Glyco_hydro_14 PF01373.17 EON33136.1 - 0.028 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Glyco_hydro_39 PF01229.17 EON33136.1 - 0.071 11.7 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Glyco_hydro_35 PF01301.19 EON33136.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_1 PF00232.18 EON33136.1 - 0.2 10.0 0.0 0.41 9.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Phage_GP20 PF06810.11 EON33137.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 Glycos_transf_1 PF00534.20 EON33138.1 - 8.8e-27 93.7 0.0 1.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON33138.1 - 7e-20 71.8 0.2 1.7e-19 70.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON33138.1 - 8.9e-09 35.6 2.8 8.9e-09 35.6 2.8 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EON33138.1 - 0.0075 16.6 0.0 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Gln-synt_N_2 PF16952.5 EON33139.1 - 0.04 13.7 0.2 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain Arc PF03869.14 EON33139.1 - 0.26 11.2 1.0 26 4.8 0.0 2.6 2 0 0 2 2 2 0 Arc-like DNA binding domain LIP PF03583.14 EON33140.1 - 1.8e-11 43.9 0.0 3.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 EON33140.1 - 2.4e-06 27.0 0.0 4.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON33140.1 - 0.005 16.4 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family GAF_2 PF13185.6 EON33141.1 - 1.9e-06 28.2 0.1 4.1e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EON33141.1 - 4.5e-05 23.8 0.0 8.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain Bac_transf PF02397.16 EON33142.1 - 4.7e-59 199.1 0.0 9.7e-59 198.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 EON33142.1 - 1.8e-09 37.9 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 CoA-binding domain DUF559 PF04480.12 EON33144.1 - 1.8e-13 50.3 0.0 3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 EON33144.1 - 3.4e-07 30.4 0.1 6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 REase_MTES_1575 OAM_dimer PF16554.5 EON33144.1 - 0.15 12.5 0.3 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase DUF2726 PF10881.8 EON33144.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) AAA_16 PF13191.6 EON33146.1 - 3e-09 37.5 2.6 6.9e-07 29.8 0.1 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EON33146.1 - 1.1e-08 35.4 0.1 0.039 14.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.17 EON33146.1 - 1.2e-07 32.1 0.0 2.8e-07 30.9 0.0 1.7 2 0 0 2 2 1 1 Helicase HerA, central domain NACHT PF05729.12 EON33146.1 - 2.3e-05 24.4 0.1 0.27 11.1 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_30 PF13604.6 EON33146.1 - 8e-05 22.4 0.5 0.064 13.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EON33146.1 - 9.4e-05 22.8 0.0 0.084 13.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain Zot PF05707.12 EON33146.1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_33 PF13671.6 EON33146.1 - 0.00068 19.8 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EON33146.1 - 0.00092 19.6 0.0 25 5.3 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 EON33146.1 - 0.003 16.2 0.0 0.021 13.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) TsaE PF02367.17 EON33146.1 - 0.0093 16.0 0.1 0.28 11.2 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EON33146.1 - 0.015 14.5 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.9 EON33146.1 - 0.015 14.2 1.6 0.07 12.0 0.0 2.7 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EON33146.1 - 0.022 14.4 0.1 7.4 6.1 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EON33146.1 - 0.031 13.5 0.0 3.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_35 PF14516.6 EON33146.1 - 0.082 11.7 0.0 4.2 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.14 EON33146.1 - 0.099 12.5 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 EON33146.1 - 0.13 11.9 0.1 25 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain T4SS-DNA_transf PF02534.14 EON33146.1 - 0.16 10.7 0.0 0.34 9.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ATP_bind_1 PF03029.17 EON33146.1 - 0.2 11.4 0.0 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIM24 PF01987.17 EON33147.1 - 1.8e-33 116.0 1.6 2.7e-33 115.5 1.6 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 TerD PF02342.18 EON33147.1 - 2.7e-20 72.6 0.0 5e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 TerD domain Polyketide_cyc2 PF10604.9 EON33148.1 - 1.6e-08 34.9 2.1 1.9e-08 34.7 2.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EON33148.1 - 1.2e-05 25.6 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein COXG PF06240.13 EON33148.1 - 0.00073 19.3 0.0 0.00095 18.9 0.0 1.3 1 1 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Ribosomal_S14 PF00253.21 EON33149.1 - 1.9e-25 88.4 2.5 2.2e-25 88.2 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2797 PF10977.8 EON33149.1 - 0.012 15.5 0.2 0.014 15.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Sgf11 PF08209.11 EON33149.1 - 0.027 14.0 2.3 3.1 7.4 0.6 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) AAA_lid_5 PF17865.1 EON33149.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Midasin AAA lid domain zf_C2H2_13 PF18508.1 EON33149.1 - 0.18 11.5 0.1 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 Zinc finger domain Ribosomal_L5_C PF00673.21 EON33150.1 - 3.8e-38 129.6 0.0 5.7e-38 129.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EON33150.1 - 2.9e-24 85.1 0.4 4.5e-24 84.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 ribosomal_L24 PF17136.4 EON33151.1 - 1.1e-23 83.4 1.5 1.7e-23 82.8 1.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EON33151.1 - 1.7e-09 37.3 1.3 1.7e-09 37.3 1.3 2.3 2 1 0 2 2 2 1 KOW motif DUF4864 PF16156.5 EON33151.1 - 0.08 13.6 0.0 0.13 13.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4864) Ribosomal_L14 PF00238.19 EON33152.1 - 1.6e-54 183.2 0.4 1.8e-54 183.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF730 PF05325.11 EON33152.1 - 0.13 12.3 0.1 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF730) AMP-binding PF00501.28 EON33153.1 - 0 1158.6 9.6 2.6e-91 306.3 0.1 5.7 4 2 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 EON33153.1 - 2.7e-236 784.5 0.0 6.4e-75 252.6 0.0 4.5 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EON33153.1 - 1.4e-49 166.3 12.3 1.5e-13 50.9 0.2 5.6 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON33153.1 - 6.2e-37 126.4 1.4 1.6e-10 41.8 0.0 5.7 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EON33153.1 - 1.4e-28 100.6 0.1 8e-28 98.1 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 EON33153.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EON33153.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MbtH PF03621.13 EON33154.1 - 1.9e-29 100.9 0.2 2.6e-29 100.4 0.2 1.2 1 0 0 1 1 1 1 MbtH-like protein ABC_tran PF00005.27 EON33155.1 - 1.8e-27 96.5 0.0 3.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON33155.1 - 3.8e-13 49.9 0.0 6.6e-09 36.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON33155.1 - 0.00013 22.4 0.1 0.00022 21.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON33155.1 - 0.00016 21.3 0.2 0.00043 20.0 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 EON33155.1 - 0.0036 17.0 0.2 0.0059 16.3 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_27 PF13514.6 EON33155.1 - 0.0036 16.9 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON33155.1 - 0.0049 16.6 2.4 0.011 15.5 2.0 1.8 1 1 0 1 1 1 1 AAA domain KdpD PF02702.17 EON33155.1 - 0.0061 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA PF00004.29 EON33155.1 - 0.0079 16.6 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 EON33155.1 - 0.019 14.8 0.2 0.044 13.6 0.2 1.5 1 0 0 1 1 1 0 MukB N-terminal AAA_23 PF13476.6 EON33155.1 - 0.046 14.2 0.1 0.077 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EON33155.1 - 0.048 13.1 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 EON33155.1 - 0.086 13.6 0.0 0.23 12.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_28 PF13521.6 EON33155.1 - 0.12 12.6 0.2 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 EON33156.1 - 1.2e-28 100.0 14.3 1.8e-28 99.4 14.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON33156.1 - 2.7e-16 59.6 5.5 2.7e-16 59.6 5.5 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 EON33156.1 - 0.0012 18.4 3.3 0.0012 18.4 3.3 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON33156.1 - 0.56 9.4 17.3 1.6 8.0 17.1 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2148 PF09918.9 EON33156.1 - 0.6 10.2 3.5 0.68 10.0 1.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Sigma70_r2 PF04542.14 EON33157.1 - 7.1e-16 57.7 0.8 7.1e-16 57.7 0.8 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON33157.1 - 2.6e-13 49.4 0.0 5.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33157.1 - 1.7e-11 43.5 0.1 4.7e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON33157.1 - 0.0021 18.0 0.1 0.0031 17.4 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor T6SS_TssG PF06996.11 EON33157.1 - 0.051 12.8 0.2 0.067 12.4 0.2 1.2 1 0 0 1 1 1 0 Type VI secretion, TssG RskA PF10099.9 EON33158.1 - 3.6e-22 79.5 27.4 3.6e-22 79.5 27.4 2.8 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Esterase PF00756.20 EON33159.1 - 4.9e-42 144.3 0.1 6.7e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 Putative esterase GerE PF00196.19 EON33160.1 - 3.1e-09 36.2 0.0 4.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_30 PF13556.6 EON33160.1 - 0.00026 20.7 0.1 0.00045 20.0 0.1 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 EON33160.1 - 0.0062 16.5 0.7 0.011 15.6 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 EON33160.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EON33160.1 - 0.052 13.2 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.7 EON33160.1 - 0.079 12.9 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 EON33160.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GerE PF00196.19 EON33161.1 - 2.2e-06 27.1 0.0 4.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 EON33161.1 - 7.1e-05 22.9 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HTH_23 PF13384.6 EON33161.1 - 0.00032 20.4 0.1 0.00072 19.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EON33161.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33161.1 - 0.0076 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 EON33161.1 - 0.026 14.5 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_10 PF04967.12 EON33161.1 - 0.057 13.2 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 HTH DNA binding domain HTH_28 PF13518.6 EON33161.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain ADC PF06314.11 EON33162.1 - 4.1e-33 114.9 0.0 5.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pirin PF02678.16 EON33163.1 - 1.1e-31 109.0 0.7 2.4e-31 107.9 0.7 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EON33163.1 - 1.7e-15 57.3 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain FMN_red PF03358.15 EON33164.1 - 5.3e-35 120.5 0.4 8.5e-35 119.8 0.1 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON33164.1 - 3e-09 36.9 0.0 5.1e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Bac_luciferase PF00296.20 EON33165.1 - 1e-57 195.9 0.6 7.9e-57 193.1 0.1 2.3 2 1 0 2 2 2 1 Luciferase-like monooxygenase DUF4878 PF12870.7 EON33166.1 - 6.2e-05 23.3 0.2 0.00018 21.8 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4878) Talin_middle PF09141.10 EON33166.1 - 0.005 16.9 5.6 0.0063 16.5 5.6 1.1 1 0 0 1 1 1 1 Talin, middle domain Lumazine_bd_2 PF12893.7 EON33166.1 - 0.036 14.8 0.0 0.09 13.5 0.0 1.6 1 1 1 2 2 2 0 Putative lumazine-binding DUF3275 PF11679.8 EON33166.1 - 0.15 12.0 5.8 0.18 11.7 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) DUF4190 PF13828.6 EON33167.1 - 8.1e-07 28.7 11.1 1.4e-06 28.0 11.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) AMP-binding PF00501.28 EON33168.1 - 0.013 14.1 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme MbtH PF03621.13 EON33169.1 - 7.5e-31 105.4 0.1 9.1e-31 105.1 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein AMP-binding PF00501.28 EON33170.1 - 0 1182.8 2.1 1e-90 304.3 0.1 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 EON33170.1 - 8.5e-252 835.7 0.0 3.5e-84 283.1 0.0 4.1 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EON33170.1 - 6.9e-56 186.5 9.0 1.2e-13 51.1 0.8 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON33170.1 - 1.3e-38 131.8 7.8 1.2e-08 35.8 0.4 5.4 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EON33170.1 - 5e-26 92.2 0.0 9.4e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain AATase PF07247.12 EON33170.1 - 0.36 9.3 0.0 12 4.3 0.0 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase AMP-binding PF00501.28 EON33171.1 - 0 3186.2 22.1 4.2e-92 309.0 0.1 11.9 12 0 0 12 12 12 11 AMP-binding enzyme Condensation PF00668.20 EON33171.1 - 0 3008.2 0.0 1.6e-82 277.7 0.0 14.1 14 0 0 14 14 14 14 Condensation domain PP-binding PF00550.25 EON33171.1 - 4.9e-161 523.3 48.2 3.9e-15 55.9 0.2 13.1 12 0 0 12 12 12 11 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON33171.1 - 4.2e-110 360.9 59.5 2.2e-13 51.0 3.0 13.1 11 0 0 11 11 11 11 AMP-binding enzyme C-terminal domain DUF211 PF02680.14 EON33171.1 - 6.3e-05 23.1 1.9 38 4.5 0.0 7.1 6 0 0 6 6 6 0 Uncharacterized ArCR, COG1888 BON PF04972.17 EON33171.1 - 0.00032 21.0 18.7 0.07 13.5 0.7 5.4 5 0 0 5 5 5 3 BON domain RHH_5 PF07878.11 EON33171.1 - 0.011 15.6 0.4 15 5.6 0.0 5.2 5 0 0 5 5 5 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF3071 PF11268.8 EON33171.1 - 0.014 15.5 0.1 12 5.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3071) RHH_1 PF01402.21 EON33171.1 - 0.016 15.2 1.2 37 4.5 0.1 5.6 6 0 0 6 6 6 0 Ribbon-helix-helix protein, copG family Sdh5 PF03937.16 EON33171.1 - 0.14 12.1 0.1 1.1e+02 2.9 0.0 4.2 5 0 0 5 5 5 0 Flavinator of succinate dehydrogenase Condensation PF00668.20 EON33172.1 - 6.4e-217 720.7 0.0 1.3e-83 281.3 0.0 3.1 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 EON33172.1 - 6.9e-176 585.0 5.2 5.9e-90 301.9 0.0 3.5 4 0 0 4 4 4 2 AMP-binding enzyme PP-binding PF00550.25 EON33172.1 - 3.1e-26 91.5 4.4 1.8e-13 50.6 0.1 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON33172.1 - 1.5e-20 73.9 3.6 6.3e-11 43.1 0.5 4.0 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EON33172.1 - 0.00051 19.9 0.3 0.11 12.2 0.0 3.7 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain ABC2_membrane PF01061.24 EON33173.1 - 9.3e-18 64.4 12.1 1.3e-17 63.9 12.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON33173.1 - 5.7e-09 35.5 14.5 7.8e-09 35.1 14.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON33173.1 - 6.7e-05 22.3 19.6 9.6e-05 21.8 18.3 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EON33173.1 - 0.31 11.0 10.9 0.013 15.5 5.4 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 EON33174.1 - 1.2e-12 47.7 11.3 1.2e-12 47.7 11.3 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON33174.1 - 1.6e-12 47.2 7.2 1.6e-12 47.2 7.2 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein MSP1a PF11670.8 EON33174.1 - 0.4 9.9 6.4 0.7 9.1 6.1 1.6 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) ABC_tran PF00005.27 EON33175.1 - 1.5e-30 106.5 0.0 2.2e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON33175.1 - 2.4e-07 30.9 0.7 0.00025 20.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON33175.1 - 9.2e-06 26.1 0.2 6.9e-05 23.3 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF4162 PF13732.6 EON33175.1 - 0.00035 21.2 0.0 0.00058 20.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SRP54 PF00448.22 EON33175.1 - 0.0025 17.5 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EON33175.1 - 0.0047 16.6 0.2 0.01 15.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON33175.1 - 0.0053 17.3 0.0 0.0077 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EON33175.1 - 0.019 15.4 0.0 0.089 13.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EON33175.1 - 0.026 14.1 0.6 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EON33175.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PsbH PF00737.20 EON33175.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein RsgA_GTPase PF03193.16 EON33175.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MukB PF04310.12 EON33175.1 - 0.11 12.2 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal KdpD PF02702.17 EON33175.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain SbcCD_C PF13558.6 EON33175.1 - 0.18 12.0 0.0 0.74 10.1 0.0 2.1 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EON33175.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 EON33176.1 - 8.2e-26 90.4 0.0 1.1e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Acetyltransf_CG PF14542.6 EON33177.1 - 1e-21 76.8 0.0 1.4e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 EON33177.1 - 5.9e-05 23.3 0.0 7.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EON33177.1 - 0.024 14.7 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON33177.1 - 0.07 13.1 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PepSY_TM_like_2 PF16357.5 EON33178.1 - 0.38 10.7 2.2 9.6 6.1 1.7 2.3 2 0 0 2 2 2 0 Putative PepSY_TM-like HATPase_c PF02518.26 EON33179.1 - 1.1e-05 25.9 0.0 2.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EON33179.1 - 0.0003 20.8 1.0 0.0003 20.8 1.0 2.2 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain Ribosomal_S17 PF00366.20 EON33180.1 - 1.3e-29 102.1 0.8 1.8e-29 101.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L29 PF00831.23 EON33181.1 - 3.4e-25 87.8 4.1 3.8e-25 87.6 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_L16 PF00252.18 EON33182.1 - 3.6e-51 172.6 0.5 4.1e-51 172.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.20 EON33183.1 - 5.7e-37 126.1 0.2 1.2e-36 125.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EON33183.1 - 4.2e-18 64.9 1.8 6.9e-18 64.2 1.8 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EON33183.1 - 0.00017 21.4 0.4 0.00045 20.0 0.4 1.7 1 0 0 1 1 1 1 KH domain Ribosomal_L22 PF00237.19 EON33184.1 - 8.3e-33 112.7 0.1 1e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 EON33185.1 - 4.1e-36 122.7 0.2 4.6e-36 122.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 EON33186.1 - 1.7e-55 186.6 4.4 3.3e-55 185.7 4.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EON33186.1 - 9.2e-34 115.2 2.2 2e-33 114.2 2.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 EON33187.1 - 5.1e-31 106.9 0.2 5.7e-31 106.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Vint PF14623.6 EON33187.1 - 0.039 13.8 0.0 0.045 13.5 0.0 1.0 1 0 0 1 1 1 0 Hint-domain Ribosomal_L4 PF00573.22 EON33188.1 - 8.9e-60 201.7 0.1 1.1e-59 201.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S15 PF00312.22 EON33188.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 Ribosomal_L3 PF00297.22 EON33189.1 - 5.6e-18 65.1 5.8 1.7e-16 60.2 1.3 2.8 2 1 1 3 3 3 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 EON33190.1 - 9.9e-35 118.7 0.1 1.1e-34 118.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF384 PF04064.13 EON33190.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) PriA_C PF18074.1 EON33190.1 - 0.031 15.1 0.0 0.29 12.0 0.0 2.0 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain DUF4442 PF14539.6 EON33191.1 - 2.9e-53 179.5 0.8 3.3e-53 179.3 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Asn_synthase PF00733.21 EON33192.1 - 1.6e-84 284.6 0.0 2e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EON33192.1 - 2.5e-42 143.7 0.0 4.3e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EON33192.1 - 4.3e-38 130.5 0.0 4.7e-37 127.2 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain tRNA_Me_trans PF03054.16 EON33192.1 - 0.002 17.0 0.1 0.0027 16.5 0.1 1.1 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EON33192.1 - 0.042 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD synthase K_oxygenase PF13434.6 EON33192.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_S9 PF00326.21 EON33193.1 - 5.3e-47 160.0 0.0 7.8e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EON33193.1 - 7e-10 39.0 1.4 1.4e-05 24.8 0.8 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EON33193.1 - 1.4e-08 34.7 0.0 0.0011 18.6 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EON33193.1 - 1.8e-08 33.9 0.3 0.00084 18.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EON33193.1 - 0.00035 20.2 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Gmad1 PF10647.9 EON33193.1 - 0.00093 19.0 9.6 0.26 11.0 5.0 2.5 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain AXE1 PF05448.12 EON33193.1 - 0.0016 17.2 0.0 0.027 13.2 0.0 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 EON33193.1 - 0.0089 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 EON33193.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EON33193.1 - 0.034 14.1 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.8 EON33193.1 - 0.035 13.3 0.0 6.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Esterase_phd PF10503.9 EON33193.1 - 0.036 13.6 0.4 0.25 10.8 0.4 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase FCD PF07729.12 EON33194.1 - 1.5e-17 64.2 7.9 3.2e-17 63.1 7.9 1.6 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON33194.1 - 2.5e-16 59.1 0.5 5e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 EON33194.1 - 8e-06 25.7 1.0 0.017 15.0 0.0 3.6 3 2 0 3 3 3 2 MarR family HTH_24 PF13412.6 EON33194.1 - 0.0048 16.4 0.0 0.058 13.0 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 EON33194.1 - 0.02 15.2 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_20 PF12840.7 EON33194.1 - 0.024 14.7 0.3 0.26 11.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 EON33194.1 - 0.052 13.4 6.3 0.063 13.1 0.6 3.1 3 1 0 3 3 3 0 IclR helix-turn-helix domain Transp_cyt_pur PF02133.15 EON33195.1 - 1e-82 278.3 42.8 1.3e-82 278.0 42.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATP1G1_PLM_MAT8 PF02038.16 EON33195.1 - 0.83 9.1 2.5 2.3 7.7 0.6 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PRD1_DD PF11087.8 EON33195.1 - 3.5 7.4 8.9 3 7.6 0.4 3.1 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery Abhydrolase_3 PF07859.13 EON33196.1 - 1.8e-48 165.2 0.3 2.3e-48 164.8 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON33196.1 - 1.2e-05 24.4 0.0 1.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EON33196.1 - 0.0042 16.4 0.1 0.21 10.9 0.0 2.4 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EON33196.1 - 0.054 13.6 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 EON33196.1 - 0.063 12.7 0.1 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.25 EON33197.1 - 4.5e-42 143.7 0.0 6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON33197.1 - 1.7e-34 119.4 0.2 2.1e-34 119.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON33197.1 - 0.00021 21.3 0.0 0.00032 20.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Rubrerythrin PF02915.17 EON33198.1 - 0.002 18.5 0.1 0.51 10.7 0.0 2.3 3 0 0 3 3 3 2 Rubrerythrin AurF PF11583.8 EON33198.1 - 0.0023 17.3 2.0 0.15 11.3 0.1 2.1 1 1 1 2 2 2 2 P-aminobenzoate N-oxygenase AurF Ferritin_2 PF13668.6 EON33198.1 - 0.0031 17.7 0.0 0.82 9.9 0.0 2.2 1 1 1 3 3 3 3 Ferritin-like domain DUF2383 PF09537.10 EON33198.1 - 0.012 16.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) FMO-like PF00743.19 EON33199.1 - 3.2e-21 75.3 0.0 3.2e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON33199.1 - 2.5e-19 69.7 0.0 1e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON33199.1 - 1.6e-13 50.5 0.0 2.3e-12 46.8 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON33199.1 - 2.3e-10 40.5 0.1 1.1e-08 35.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EON33199.1 - 5e-10 39.1 0.4 6.9e-09 35.3 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON33199.1 - 7.1e-09 35.7 0.6 0.0042 16.7 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON33199.1 - 1.7e-05 25.3 0.1 0.27 11.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EON33199.1 - 5.4e-05 22.7 0.0 0.034 13.4 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EON33199.1 - 0.00011 22.3 0.4 1.1 9.3 0.0 3.7 3 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON33199.1 - 0.0015 17.7 0.0 0.0082 15.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EON33199.1 - 0.0054 15.5 0.2 1.8 7.2 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.20 EON33199.1 - 0.0098 16.0 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EON33199.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.12 EON33199.1 - 0.17 11.4 0.2 14 5.2 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EON33199.1 - 0.2 10.7 0.1 2 7.4 0.3 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A MerR_1 PF13411.6 EON33200.1 - 6.4e-18 64.6 0.3 1.1e-16 60.7 0.1 2.3 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 EON33200.1 - 2e-05 24.2 0.4 2e-05 24.2 0.4 2.2 3 0 0 3 3 3 1 MerR family regulatory protein YrhK PF14145.6 EON33201.1 - 0.001 18.9 27.9 0.39 10.6 7.8 5.0 3 2 0 3 3 3 3 YrhK-like protein Putative_PNPOx PF01243.20 EON33202.1 - 5.3e-12 45.8 0.0 6.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON33202.1 - 3.1e-09 37.0 0.0 3.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GMC_oxred_N PF00732.19 EON33203.1 - 6e-29 101.3 0.0 8.3e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EON33203.1 - 1.6e-09 38.4 0.1 3.1e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EON33203.1 - 7.7e-07 29.0 2.7 0.00011 21.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EON33203.1 - 5.7e-06 25.7 0.1 0.00021 20.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EON33203.1 - 1.4e-05 24.3 0.2 2.1e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EON33203.1 - 4.5e-05 23.6 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON33203.1 - 0.00023 20.4 1.6 0.0028 16.8 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EON33203.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON33203.1 - 0.0092 14.7 0.2 0.015 14.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 EON33203.1 - 0.01 15.5 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EON33203.1 - 0.026 13.8 0.2 0.038 13.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EON33203.1 - 0.052 14.1 0.0 0.17 12.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON33203.1 - 0.091 11.8 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON33203.1 - 0.16 12.0 0.3 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glycos_transf_2 PF00535.26 EON33204.1 - 5.6e-21 75.1 0.0 1.1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON33204.1 - 5.9e-12 46.0 2.1 8.9e-12 45.4 1.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EON33204.1 - 6.9e-10 38.7 0.1 2.2e-09 37.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EON33204.1 - 5.2e-07 29.8 1.8 7.1e-07 29.3 1.8 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 EON33204.1 - 2.9e-06 27.0 0.0 7.2e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 EON33204.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Creatininase PF02633.14 EON33205.1 - 1.1e-54 185.5 0.0 1.3e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase CoA_transf_3 PF02515.17 EON33206.1 - 3.4e-78 263.3 0.1 4.4e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.25 EON33207.1 - 1.4e-44 151.9 1.5 1.1e-43 149.0 1.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON33207.1 - 1.6e-44 152.2 2.5 7.5e-44 150.0 2.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON33207.1 - 2.3e-09 37.4 0.1 3.3e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_dim PF02852.22 EON33207.1 - 0.023 14.9 0.0 0.2 11.9 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FMN_dh PF01070.18 EON33208.1 - 1.7e-101 339.8 0.2 1.9e-101 339.6 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EON33208.1 - 2.9e-07 30.2 1.1 5.7e-07 29.2 1.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EON33208.1 - 3.1e-07 29.7 2.1 5.6e-07 28.9 1.0 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EON33208.1 - 2.1e-05 23.8 0.4 3.3e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EON33208.1 - 4.7e-05 23.0 0.2 0.0028 17.2 0.0 2.8 1 1 2 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 EON33208.1 - 0.00068 19.0 0.2 0.011 15.1 0.7 2.3 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 EON33208.1 - 0.0082 15.3 0.2 0.033 13.3 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EON33208.1 - 0.071 12.3 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EON33208.1 - 0.074 12.5 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PA PF02225.22 EON33208.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.6 2 1 0 2 2 2 0 PA domain IGPS PF00218.21 EON33208.1 - 0.17 11.0 0.0 1.3 8.1 0.0 2.2 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase Radical_SAM PF04055.21 EON33209.1 - 6.7e-25 88.4 0.0 1e-24 87.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 EON33209.1 - 1.1e-06 29.1 0.2 2.4e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 EON33209.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EON33209.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain TetR_C_14 PF17754.1 EON33212.1 - 8.7e-41 138.4 1.2 1.3e-40 137.9 1.2 1.2 1 0 0 1 1 1 1 MftR C-terminal domain TetR_N PF00440.23 EON33212.1 - 1.2e-12 47.4 0.1 2.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 EON33212.1 - 0.002 18.2 0.0 0.0049 17.0 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 EON33212.1 - 0.021 14.9 0.1 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EON33212.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain NAD_binding_1 PF00175.21 EON33213.1 - 5.4e-15 56.0 0.0 1.1e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 EON33213.1 - 3.8e-14 52.4 0.4 8.7e-14 51.2 0.4 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 EON33213.1 - 1.6e-07 31.6 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EON33213.1 - 0.00068 19.8 0.0 0.0015 18.7 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_4 PF13510.6 EON33213.1 - 0.096 12.7 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DoxX_3 PF13781.6 EON33214.1 - 1.5e-05 25.5 0.5 4.7e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 DoxX-like family DUF4267 PF14087.6 EON33214.1 - 0.073 13.1 0.2 0.14 12.2 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) DoxX PF07681.12 EON33214.1 - 0.59 10.8 5.4 0.13 12.9 1.9 1.7 2 1 0 2 2 2 0 DoxX Ribosomal_L1 PF00687.21 EON33216.1 - 1.7e-51 174.8 0.0 2.2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11_N PF03946.14 EON33217.1 - 5.7e-30 102.9 0.1 1.1e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EON33217.1 - 1.8e-29 102.0 1.2 3.1e-29 101.3 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SBP_bac_5 PF00496.22 EON33217.1 - 0.0038 16.2 0.1 0.0047 15.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle NusG PF02357.19 EON33218.1 - 2.8e-25 88.7 0.0 5.8e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 EON33218.1 - 0.029 14.3 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 KOW motif SecE PF00584.20 EON33219.1 - 4.7e-20 71.3 8.7 6.2e-20 70.9 8.7 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAM-associated PF14303.6 EON33219.1 - 0.34 11.6 4.0 0.39 11.4 4.0 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MaoC_dehydrat_N PF13452.6 EON33220.1 - 7.7e-43 145.8 0.1 6e-36 123.5 0.1 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 EON33220.1 - 4.2e-22 78.0 0.5 5.4e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 MaoC like domain Ribosomal_L33 PF00471.20 EON33221.1 - 6.2e-23 81.0 5.6 6.9e-23 80.8 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 zf-ribbon_3 PF13248.6 EON33221.1 - 0.0082 15.5 2.1 0.022 14.2 0.4 2.0 2 0 0 2 2 2 1 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EON33221.1 - 0.013 15.3 1.5 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 EON33221.1 - 0.022 14.8 1.0 0.026 14.5 1.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 EON33221.1 - 0.03 14.0 0.7 0.03 14.0 0.7 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 EON33221.1 - 0.033 14.3 1.6 0.05 13.6 0.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 EON33221.1 - 0.058 13.5 2.8 0.11 12.6 2.7 1.6 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 EON33221.1 - 0.078 13.0 3.0 0.14 12.2 3.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 EON33221.1 - 0.081 13.1 4.5 0.16 12.1 4.5 1.5 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.12 EON33221.1 - 0.12 12.0 2.7 0.3 10.6 2.7 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding TFIIS_C PF01096.18 EON33221.1 - 0.16 11.8 3.9 3.8 7.4 0.6 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Nudix_N_2 PF14803.6 EON33221.1 - 0.26 11.2 4.6 0.29 11.1 0.8 2.2 2 0 0 2 2 2 0 Nudix N-terminal DUF520 PF04461.13 EON33222.1 - 2.9e-60 203.1 1.7 3.2e-60 202.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) GGDEF PF00990.21 EON33222.1 - 0.012 15.3 0.5 0.5 10.1 0.1 2.4 2 1 1 3 3 3 0 Diguanylate cyclase, GGDEF domain Microtub_bd PF16796.5 EON33222.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding Peptidase_M48 PF01435.18 EON33223.1 - 7.3e-38 130.3 0.2 1.2e-37 129.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EON33223.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 BSP PF04450.12 EON33223.1 - 0.09 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria polyprenyl_synt PF00348.17 EON33224.1 - 1.2e-58 198.2 0.0 1.4e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase FAD_binding_3 PF01494.19 EON33225.1 - 7.8e-15 55.0 3.4 4e-14 52.6 3.4 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EON33225.1 - 6.1e-06 25.8 5.4 1.7e-05 24.3 5.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EON33225.1 - 0.0003 20.5 6.0 0.18 11.3 1.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON33225.1 - 0.00041 19.7 1.4 0.00078 18.8 1.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON33225.1 - 0.00053 18.9 0.8 1.4 7.7 0.2 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EON33225.1 - 0.0016 18.6 0.5 0.0059 16.8 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EON33225.1 - 0.048 12.7 2.4 0.066 12.3 2.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EON33225.1 - 0.052 12.2 3.9 0.023 13.4 1.5 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EON33225.1 - 0.15 11.0 8.0 2.2 7.2 8.0 2.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EON33225.1 - 0.37 9.8 11.5 0.084 11.9 5.1 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 EON33225.1 - 0.54 9.5 4.7 0.089 12.1 1.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2236 PF09995.9 EON33226.1 - 2.3e-18 67.3 0.2 3.8e-18 66.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Ubie_methyltran PF01209.18 EON33227.1 - 8.1e-59 198.8 0.0 1e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EON33227.1 - 8.5e-19 68.0 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON33227.1 - 1.2e-15 58.0 0.1 2.1e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON33227.1 - 1.6e-11 44.3 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON33227.1 - 5.8e-09 35.9 0.0 9.5e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON33227.1 - 4.3e-07 30.6 0.0 7.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EON33227.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Glyco_transf_4 PF13439.6 EON33228.1 - 7.1e-22 78.2 4.6 1.1e-21 77.6 3.3 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EON33228.1 - 1.9e-20 73.1 0.0 7.5e-20 71.2 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON33228.1 - 6.9e-18 65.4 1.4 5.9e-17 62.3 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON33228.1 - 1.1e-14 55.2 15.2 1.1e-14 55.2 15.2 2.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EON33228.1 - 1.9e-06 28.0 0.0 5.1e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EON33228.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Peptidase_S51 PF03575.17 EON33229.1 - 5.3e-35 121.0 0.0 6.2e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 GATase_3 PF07685.14 EON33229.1 - 0.0042 16.7 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain UPF0180 PF03698.13 EON33229.1 - 0.047 13.9 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) LapA_dom PF06305.11 EON33230.1 - 0.033 14.0 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TPP_enzyme_N PF02776.18 EON33231.1 - 8.6e-27 93.8 0.7 2e-26 92.6 0.7 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON33231.1 - 0.026 14.3 1.9 0.043 13.6 0.1 2.3 2 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Methyltransf_11 PF08241.12 EON33232.1 - 4.1e-14 53.0 0.0 5.9e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON33232.1 - 1.2e-10 41.5 0.0 1.5e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON33232.1 - 1.5e-09 38.5 0.0 2.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON33232.1 - 3e-07 30.0 0.0 3.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EON33232.1 - 0.00016 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON33232.1 - 0.00042 21.0 0.0 0.00063 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EON33232.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) AbrB PF05145.12 EON33233.1 - 1.4e-72 244.3 43.3 1.4e-72 244.3 43.3 1.9 1 1 1 2 2 2 2 Transition state regulatory protein AbrB Sacchrp_dh_NADP PF03435.18 EON33234.1 - 4.7e-12 46.3 0.1 9.5e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EON33234.1 - 0.036 14.5 0.0 0.087 13.3 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EON33234.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 EON33234.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON33234.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family HSP20 PF00011.21 EON33235.1 - 5.1e-19 68.3 0.0 5.8e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EON33235.1 - 3.2e-12 45.8 0.0 5.7e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 EON33235.1 - 0.031 14.6 0.1 0.61 10.4 0.0 2.5 3 0 0 3 3 3 0 BON domain GvpH PF05455.11 EON33235.1 - 0.085 12.9 0.3 0.17 12.0 0.2 1.4 1 1 0 1 1 1 0 GvpH EAL PF00563.20 EON33236.1 - 3.2e-59 200.4 0.0 4.4e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EON33237.1 - 1.1e-27 96.8 0.0 8.6e-27 93.9 0.0 2.0 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CcmD PF04995.14 EON33237.1 - 0.45 10.7 0.1 0.45 10.7 0.1 3.2 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) Trp_oprn_chp PF09534.10 EON33237.1 - 4.4 7.1 14.8 1.2 9.0 0.2 2.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ThiF PF00899.21 EON33239.1 - 3.4e-22 79.0 0.0 5.3e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Nitroreductase PF00881.24 EON33239.1 - 1.4e-07 31.7 2.9 0.013 15.5 0.1 3.4 2 2 1 3 3 3 2 Nitroreductase family TM1586_NiRdase PF14512.6 EON33239.1 - 5.2e-05 22.9 0.0 7.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Ldh_1_N PF00056.23 EON33239.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 4HBT PF03061.22 EON33240.1 - 9.7e-06 25.9 1.5 1.2e-05 25.6 0.3 1.8 2 0 0 2 2 2 1 Thioesterase superfamily ECH_1 PF00378.20 EON33242.1 - 3e-57 193.8 0.0 6.8e-44 150.1 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON33242.1 - 5.1e-14 52.5 0.1 4.8e-13 49.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4012 PF13196.6 EON33243.1 - 5.6e-41 140.4 0.0 1.1e-40 139.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4012) DUF4115 PF13464.6 EON33243.1 - 0.0011 19.1 0.2 1 9.6 0.0 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4115) LMWPc PF01451.21 EON33244.1 - 4e-26 92.1 0.0 7.8e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase AMP-binding PF00501.28 EON33245.1 - 1.4e-260 864.0 32.3 5.7e-82 275.6 3.1 7.7 6 2 0 6 6 6 5 AMP-binding enzyme Condensation PF00668.20 EON33245.1 - 1.9e-229 762.0 0.0 2.3e-62 211.2 0.0 5.2 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 EON33245.1 - 1.6e-58 195.0 11.6 5.5e-14 52.3 0.0 6.1 5 0 0 5 5 5 5 Phosphopantetheine attachment site Thioesterase PF00975.20 EON33245.1 - 4.4e-22 79.3 0.0 9.1e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 EON33245.1 - 1.3e-20 74.1 8.3 8e-06 26.7 0.0 7.4 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain Bac_luciferase PF00296.20 EON33246.1 - 9.3e-64 215.8 1.1 1.1e-63 215.6 1.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase XdhC_C PF13478.6 EON33246.1 - 0.044 14.3 0.3 8.9 6.8 0.0 2.5 1 1 1 2 2 2 0 XdhC Rossmann domain PHO4 PF01384.20 EON33247.1 - 3.6e-76 256.4 36.5 2e-75 254.0 36.5 1.9 1 1 0 1 1 1 1 Phosphate transporter family FixQ PF05545.11 EON33247.1 - 0.046 13.7 1.0 1.6 8.8 0.0 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TgMIC1 PF11476.8 EON33247.1 - 0.054 13.3 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF4131 PF13567.6 EON33247.1 - 0.086 12.5 0.1 0.086 12.5 0.1 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) OPA3 PF07047.12 EON33247.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF202 PF02656.15 EON33248.1 - 0.17 12.3 2.2 0.22 12.0 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 EON33248.1 - 0.27 11.3 5.0 0.36 10.9 5.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Saf_2TM PF18303.1 EON33248.1 - 1.7 8.2 4.5 1.9 8.1 4.5 1.3 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain DUF3349 PF11829.8 EON33249.1 - 8e-34 116.3 0.1 9.5e-34 116.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3349) GP67 PF17634.2 EON33249.1 - 0.005 17.2 0.5 0.0069 16.8 0.5 1.2 1 0 0 1 1 1 1 Gene product 67 AMP-binding PF00501.28 EON33250.1 - 1.6e-36 125.8 0.0 2.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON33250.1 - 7.9e-15 55.6 0.4 1.5e-14 54.7 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MTES_1575 PF18741.1 EON33251.1 - 2.5e-10 40.4 0.0 5.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 EON33251.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) AbiEi_4 PF13338.6 EON33251.1 - 0.00014 21.9 2.1 0.00031 20.8 1.2 2.1 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin UPF0102 PF02021.17 EON33251.1 - 0.03 14.5 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 DUF3341 PF11821.8 EON33251.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) UbiA PF01040.18 EON33252.1 - 1.9e-33 115.8 28.0 1.9e-33 115.8 28.0 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family PRA1 PF03208.19 EON33252.1 - 7 6.3 9.8 9.8 5.8 1.9 2.6 2 0 0 2 2 2 0 PRA1 family protein Clp_N PF02861.20 EON33253.1 - 1.4e-12 47.5 6.9 1.7e-05 24.8 0.2 3.2 3 0 0 3 3 3 3 Clp amino terminal domain, pathogenicity island component HTH_23 PF13384.6 EON33254.1 - 0.0013 18.4 1.0 0.0021 17.8 1.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EON33254.1 - 0.0041 16.6 0.1 0.0078 15.7 0.1 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EON33254.1 - 0.0063 16.2 0.1 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 EON33254.1 - 0.007 16.3 0.1 0.018 15.0 0.0 1.7 1 1 1 2 2 2 1 HTH domain UPF0122 PF04297.14 EON33254.1 - 0.064 13.5 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like FtsX PF02687.21 EON33255.1 - 1.3e-16 60.8 9.1 2.6e-11 43.8 2.9 6.1 7 1 0 7 7 7 2 FtsX-like permease family Molydop_binding PF01568.21 EON33255.1 - 0.091 12.8 0.5 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain DUF3094 PF11293.8 EON33255.1 - 0.68 9.7 5.0 0.75 9.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) ABC_tran PF00005.27 EON33256.1 - 3.6e-32 111.8 0.0 4.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON33256.1 - 0.00015 21.7 0.7 0.28 11.0 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON33256.1 - 0.00053 20.4 0.1 0.0011 19.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON33256.1 - 0.002 18.0 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EON33256.1 - 0.0021 17.7 0.4 0.0038 16.9 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON33256.1 - 0.0026 17.2 0.1 2.3 7.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON33256.1 - 0.0058 16.9 0.2 0.023 14.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON33256.1 - 0.02 14.6 0.3 0.034 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EON33256.1 - 0.054 13.6 0.4 0.11 12.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EON33256.1 - 0.15 11.7 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 EON33256.1 - 0.24 11.9 0.0 0.3 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain PALP PF00291.25 EON33257.1 - 7.7e-44 150.3 0.1 9.7e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4229 PF14012.6 EON33258.1 - 8.5e-19 67.4 8.7 1.2e-18 66.9 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) HTH_17 PF12728.7 EON33259.1 - 1.3e-11 44.5 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MerR_1 PF13411.6 EON33259.1 - 2.2e-07 30.9 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EON33259.1 - 3.5e-07 29.9 0.0 5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 MerR family regulatory protein HTH_29 PF13551.6 EON33259.1 - 0.00096 19.1 0.1 0.058 13.4 0.1 2.1 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EON33259.1 - 0.0011 19.1 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON33259.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain AbiEi_4 PF13338.6 EON33259.1 - 0.037 14.2 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Terminase_5 PF06056.12 EON33259.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) PGF-CTERM PF18204.1 EON33260.1 - 0.036 14.0 2.5 0.05 13.6 2.5 1.2 1 0 0 1 1 1 0 PGF-CTERM motif HTH_3 PF01381.22 EON33261.1 - 1.1e-06 28.5 0.0 4.2e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EON33261.1 - 9.1e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EON33261.1 - 4.2e-05 23.8 0.0 0.00017 21.8 0.0 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 EON33261.1 - 0.00084 19.7 0.0 0.0023 18.3 0.0 1.7 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain MRP-L20 PF12824.7 EON33261.1 - 0.058 13.6 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Cytochrom_C_asm PF01578.20 EON33262.1 - 3e-44 151.4 13.7 3e-44 151.4 13.7 1.7 2 0 0 2 2 2 1 Cytochrome C assembly protein DUF3188 PF11384.8 EON33262.1 - 0.13 12.0 0.2 0.13 12.0 0.2 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3188) BCHF PF07284.11 EON33262.1 - 0.73 9.8 4.7 0.55 10.3 0.4 2.5 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) ResB PF05140.14 EON33263.1 - 6.4e-124 414.4 0.0 1.5e-123 413.1 0.0 1.5 1 1 0 1 1 1 1 ResB-like family DsbD PF02683.15 EON33264.1 - 2.5e-44 151.7 14.6 3.4e-44 151.3 14.6 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Redoxin PF08534.10 EON33265.1 - 3e-16 59.5 0.0 4.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EON33265.1 - 1.4e-15 57.3 0.0 2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EON33265.1 - 4.7e-07 30.0 0.0 8.5e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EON33265.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PT-TG PF14449.6 EON33265.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin TG GSHPx PF00255.19 EON33265.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione peroxidase His_Phos_1 PF00300.22 EON33266.1 - 1.8e-35 122.4 0.1 2.2e-35 122.1 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ZnuA PF01297.17 EON33266.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Aminotran_3 PF00202.21 EON33267.1 - 8.7e-84 281.5 0.0 1e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EON33267.1 - 6.2e-06 25.6 0.0 9.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_GDSL_2 PF13472.6 EON33268.1 - 1.3e-29 103.9 0.2 1.7e-29 103.5 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON33268.1 - 4.8e-12 46.3 0.0 7.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aldedh PF00171.22 EON33269.1 - 2.7e-157 524.0 0.0 3.3e-157 523.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF218 PF02698.17 EON33270.1 - 8.4e-24 84.1 0.8 1e-23 83.8 0.1 1.4 2 0 0 2 2 2 1 DUF218 domain AAA_33 PF13671.6 EON33270.1 - 0.045 13.9 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zea_mays_MuDR PF05928.11 EON33270.1 - 0.22 11.1 2.0 0.37 10.4 2.0 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF2749 PF10907.8 EON33270.1 - 0.28 11.4 4.3 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Acyl-CoA_dh_1 PF00441.24 EON33271.1 - 3.6e-50 170.1 1.5 5.3e-50 169.5 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON33271.1 - 8.5e-31 106.0 0.0 1.9e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON33271.1 - 5.3e-29 101.2 0.0 9.2e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON33271.1 - 4.2e-26 91.8 0.7 9.5e-26 90.7 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_N PF00440.23 EON33272.1 - 7.3e-15 54.5 0.3 7.3e-15 54.5 0.3 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_AraC PF00165.23 EON33272.1 - 0.01 15.9 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_C_14 PF17754.1 EON33272.1 - 0.019 14.9 5.0 0.019 14.9 3.3 1.9 1 1 1 2 2 2 0 MftR C-terminal domain HTH_18 PF12833.7 EON33272.1 - 0.051 13.8 0.7 0.44 10.8 0.2 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 EON33272.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase ACOX PF01756.19 EON33273.1 - 5.8e-24 84.6 0.1 1.1e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EON33273.1 - 7.8e-18 64.5 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON33273.1 - 5e-10 40.0 0.1 2.2e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON33273.1 - 1.2e-08 35.3 3.9 2.9e-08 34.0 1.9 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3093 PF11292.8 EON33275.1 - 0.012 15.9 1.1 0.018 15.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) YwiC PF14256.6 EON33275.1 - 0.023 15.0 1.0 0.033 14.5 1.0 1.2 1 0 0 1 1 1 0 YwiC-like protein EbsA PF17255.2 EON33275.1 - 0.12 12.7 0.4 0.15 12.4 0.4 1.2 1 0 0 1 1 1 0 EbsA-like protein Halogen_Hydrol PF10112.9 EON33276.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YtpI PF14007.6 EON33276.1 - 0.53 10.5 9.0 0.097 12.8 2.3 2.2 2 0 0 2 2 2 0 YtpI-like protein EcsB PF05975.12 EON33276.1 - 1.3 7.8 9.5 1.6 7.5 9.5 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Bax1-I PF01027.20 EON33276.1 - 9.1 6.0 18.4 12 5.7 18.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 EON33277.1 - 0.01 15.8 5.0 0.013 15.4 5.0 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling 7tm_3 PF00003.22 EON33277.1 - 0.014 15.1 1.7 0.018 14.8 1.7 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Innate_immun PF12782.7 EON33277.1 - 0.03 13.9 8.6 0.15 11.6 3.8 2.1 1 1 1 2 2 2 0 Invertebrate innate immunity transcript family TctB PF07331.11 EON33277.1 - 0.033 14.5 4.8 0.052 13.8 3.7 1.8 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2070 PF09843.9 EON33277.1 - 0.42 8.8 5.4 0.52 8.5 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_3_6 PF07332.11 EON33277.1 - 0.65 10.0 7.5 0.42 10.7 5.1 1.9 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III VIT1 PF01988.19 EON33277.1 - 3.5 7.4 10.7 1.6 8.6 8.6 1.4 1 1 1 2 2 2 0 VIT family ALAD PF00490.21 EON33278.1 - 7.8e-137 455.7 0.1 8.8e-137 455.5 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HEM4 PF02602.15 EON33279.1 - 1.8e-63 214.0 0.3 4.8e-63 212.6 0.0 1.8 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD TP_methylase PF00590.20 EON33279.1 - 2e-37 129.2 10.0 6.6e-37 127.5 10.0 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Porphobil_deam PF01379.20 EON33280.1 - 4.4e-66 222.3 0.1 6.2e-66 221.8 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EON33280.1 - 1.2e-18 67.2 1.2 2.5e-18 66.2 0.7 1.8 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain GlutR_N PF05201.15 EON33281.1 - 5.8e-46 155.9 0.2 1.2e-45 154.9 0.2 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EON33281.1 - 1.6e-26 93.0 0.0 3.1e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EON33281.1 - 5e-22 78.2 0.9 5e-22 78.2 0.9 2.0 3 0 0 3 3 3 1 Glutamyl-tRNAGlu reductase, dimerisation domain Glu_dehyd_C PF16912.5 EON33281.1 - 8.2e-06 25.4 1.3 2.1e-05 24.1 1.3 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 EON33281.1 - 0.00022 21.5 2.1 0.0009 19.5 2.1 2.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EON33281.1 - 0.0011 19.5 1.3 0.0011 19.5 1.3 3.2 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EON33281.1 - 0.0074 15.9 1.3 0.013 15.1 0.7 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 EON33281.1 - 0.013 15.7 0.7 0.038 14.2 0.7 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EON33281.1 - 0.072 12.4 0.9 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 ThiF family Put_DNA-bind_N PF06971.13 EON33282.1 - 3.1e-15 55.9 0.0 5.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus CoA_binding PF02629.19 EON33282.1 - 2.6e-09 37.7 0.1 5.5e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain DUF836 PF05768.14 EON33283.1 - 5.9e-12 45.8 0.0 6.5e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EON33283.1 - 5.1e-06 26.6 0.0 7.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin HAD PF12710.7 EON33284.1 - 1.7e-28 100.3 0.4 3e-28 99.5 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON33284.1 - 2.6e-09 37.7 2.4 5.8e-09 36.5 0.7 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON33284.1 - 6.6e-07 29.3 0.0 4.9e-06 26.5 0.0 2.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DUF222 PF02720.17 EON33285.1 - 6.1e-35 121.1 17.6 6.1e-35 121.1 17.6 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF222) DUF4232 PF14016.6 EON33285.1 - 0.0071 16.5 5.2 0.018 15.2 5.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) ADH_zinc_N PF00107.26 EON33286.1 - 4.2e-14 52.6 0.6 3.1e-13 49.8 0.1 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON33286.1 - 2.4e-12 46.7 0.4 8.8e-11 41.7 0.4 2.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EON33286.1 - 0.00027 22.0 0.0 0.018 16.1 0.0 2.4 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON33286.1 - 0.00039 20.0 0.1 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EON33286.1 - 0.058 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EON33286.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Acyltransferase PF01553.21 EON33287.1 - 2.3e-13 49.9 0.0 3.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 EON33287.1 - 0.024 13.6 0.0 0.04 12.8 0.0 1.5 1 1 0 1 1 1 0 Diacylglycerol acyltransferase Epimerase PF01370.21 EON33288.1 - 8.1e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON33288.1 - 3.4e-11 42.7 0.0 4.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EON33288.1 - 2e-10 40.6 0.0 4.2e-09 36.2 0.0 2.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EON33288.1 - 8.3e-08 31.7 0.2 5.6e-05 22.4 0.1 2.4 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EON33288.1 - 0.0013 18.0 0.0 0.0022 17.2 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1713 PF08213.11 EON33289.1 - 3.6e-12 46.0 21.3 3.8e-12 45.9 21.3 1.0 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) HTH_17 PF12728.7 EON33290.1 - 1.8e-14 53.6 0.0 2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EON33290.1 - 0.0011 18.7 0.0 0.0035 17.1 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EON33290.1 - 0.0038 16.6 0.3 0.028 13.8 0.1 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 EON33290.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_22 PF13309.6 EON33290.1 - 0.019 15.1 0.2 0.031 14.4 0.2 1.3 1 0 0 1 1 1 0 HTH domain Phage_Cox PF10743.9 EON33290.1 - 0.021 14.9 0.0 0.021 14.9 0.0 1.0 1 0 0 1 1 1 0 Regulatory phage protein cox LacI PF00356.21 EON33290.1 - 0.029 14.2 0.3 0.038 13.8 0.3 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_38 PF13936.6 EON33290.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 EON33290.1 - 0.045 13.9 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_DeoR PF08220.12 EON33290.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_7 PF02796.15 EON33290.1 - 0.059 13.4 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Soyouz_module PF14313.6 EON33290.1 - 0.086 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Sigma70_r4_2 PF08281.12 EON33290.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33290.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 EON33290.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain P5CR_dimer PF14748.6 EON33291.1 - 2.3e-36 124.2 2.9 4.3e-36 123.3 2.9 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EON33291.1 - 5.3e-19 68.6 0.8 1.2e-18 67.4 0.8 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EON33291.1 - 3.3e-05 24.0 0.1 5.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EON33291.1 - 4.3e-05 23.1 0.0 7.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 EON33291.1 - 0.00025 21.2 0.2 0.00067 19.9 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EON33291.1 - 0.00097 19.4 0.4 0.0029 17.9 0.4 1.8 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EON33291.1 - 0.0026 18.0 0.2 0.0066 16.7 0.2 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 EON33291.1 - 0.01 16.7 0.3 0.027 15.3 0.1 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 EON33291.1 - 0.097 13.1 0.6 0.36 11.3 0.2 2.1 1 1 0 2 2 2 0 Putative NAD(P)-binding DUF1995 PF09353.10 EON33291.1 - 0.34 10.9 2.8 3.4 7.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1995) 3HCDH_N PF02737.18 EON33291.1 - 0.6 10.0 4.4 1.5 8.7 0.2 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4HBT_3 PF13622.6 EON33292.1 - 6.6e-34 118.3 1.6 7.5e-34 118.1 1.6 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily PS-DH PF14765.6 EON33292.1 - 0.048 12.9 0.2 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Polyketide synthase dehydratase AP_endonuc_2 PF01261.24 EON33293.1 - 7.3e-18 64.8 1.1 1.5e-17 63.8 0.4 1.9 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel Tweety PF04906.13 EON33294.1 - 1.8 7.1 2.9 2.6 6.6 2.9 1.1 1 0 0 1 1 1 0 Tweety SOG2 PF10428.9 EON33294.1 - 7 5.7 25.5 12 5.0 25.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Ppx-GppA PF02541.16 EON33295.1 - 1.4e-80 270.8 0.0 1.7e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Trans_reg_C PF00486.28 EON33297.1 - 1.2e-28 98.9 0.1 5.3e-28 96.9 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EON33297.1 - 1.3e-27 96.2 0.0 1.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EON33298.1 - 5.3e-24 84.9 0.0 9.1e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON33298.1 - 3e-14 52.8 0.1 7.2e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EON33298.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acetyltransf_CG PF14542.6 EON33299.1 - 1.2e-23 83.0 0.1 1.4e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 EON33299.1 - 0.0023 18.1 0.0 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EON33299.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.5 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_7 PF13508.7 EON33299.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON33299.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain His_Phos_1 PF00300.22 EON33300.1 - 7.9e-36 123.6 0.1 3.6e-33 114.9 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AA_permease_2 PF13520.6 EON33301.1 - 5e-43 147.5 38.3 6.2e-43 147.2 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON33301.1 - 3e-36 125.0 34.5 4e-36 124.6 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EON33301.1 - 3.3e-05 22.9 21.0 7.4e-05 21.7 14.9 2.6 2 1 0 2 2 2 2 Spore germination protein Tmemb_18A PF09771.9 EON33301.1 - 1.6 9.1 4.0 1.8 9.0 1.3 2.5 2 0 0 2 2 2 0 Transmembrane protein 188 AMP-binding PF00501.28 EON33302.1 - 2.8e-100 335.9 0.0 3.3e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON33302.1 - 1.5e-14 54.7 1.9 3.9e-14 53.4 1.5 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain YbjN PF10722.9 EON33303.1 - 1.8e-23 83.0 0.0 2.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator CesT PF05932.13 EON33303.1 - 0.042 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family Glycos_transf_1 PF00534.20 EON33304.1 - 3.5e-34 117.8 0.0 6.4e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON33304.1 - 1.6e-31 109.6 4.3 3.2e-31 108.6 0.3 2.8 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON33304.1 - 2.3e-29 102.9 8.9 2.3e-29 102.9 8.9 3.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EON33304.1 - 2e-26 93.0 0.7 3.6e-26 92.2 0.2 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EON33304.1 - 4.5e-12 46.2 0.0 1.4e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EON33304.1 - 0.001 18.8 2.8 0.016 14.9 0.1 2.5 2 1 1 3 3 3 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 EON33304.1 - 0.007 16.4 0.0 0.055 13.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like ZnuA PF01297.17 EON33305.1 - 1.1e-44 152.8 4.0 1.2e-44 152.7 4.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Gon7 PF08738.10 EON33305.1 - 0.03 14.4 1.1 8.7 6.5 0.0 2.5 2 1 0 2 2 2 0 Gon7 family ABC_tran PF00005.27 EON33306.1 - 1.7e-19 70.7 0.0 3.8e-19 69.6 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON33306.1 - 4.5e-11 43.1 0.0 0.00013 21.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON33306.1 - 2.5e-06 27.1 0.0 0.034 13.6 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON33306.1 - 0.0012 19.3 0.1 0.0021 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EON33306.1 - 0.0042 16.8 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EON33306.1 - 0.018 14.6 0.0 0.35 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EON33306.1 - 0.019 15.3 0.0 0.051 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EON33306.1 - 0.028 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 EON33306.1 - 0.051 13.7 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 EON33306.1 - 0.054 14.0 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON33306.1 - 0.082 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EON33306.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2791 PF10923.8 EON33306.1 - 0.2 10.4 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA12 PF10443.9 EON33306.1 - 0.22 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Dynamin_N PF00350.23 EON33306.1 - 0.22 11.5 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Pox_A32 PF04665.12 EON33306.1 - 0.3 10.5 0.0 0.44 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein ABC-3 PF00950.17 EON33307.1 - 3.4e-41 141.5 35.9 3.8e-41 141.3 35.9 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 EON33307.1 - 0.0031 16.5 36.9 0.0047 16.0 36.9 1.3 1 0 0 1 1 1 1 FecCD transport family BPD_transp_2 PF02653.16 EON33307.1 - 0.0066 15.6 12.2 0.0066 15.6 12.2 3.6 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component DUF2599 PF10783.9 EON33308.1 - 5.1e-35 120.0 0.0 6.5e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2599) LPAM_2 PF13627.6 EON33308.1 - 0.017 14.9 3.5 0.035 14.0 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF3558 PF12079.8 EON33308.1 - 0.59 10.1 6.0 1.1 9.2 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Cellulase PF00150.18 EON33309.1 - 0.00046 19.7 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PMT_2 PF13231.6 EON33310.1 - 9.5e-09 35.7 8.2 9.5e-09 35.7 8.2 3.5 2 2 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_tranf_2_3 PF13641.6 EON33311.1 - 2e-31 109.6 0.0 3.1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON33311.1 - 2.6e-21 76.5 4.9 4.5e-21 75.7 4.6 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EON33311.1 - 4.6e-09 36.3 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EON33311.1 - 3.4e-06 26.7 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1700 PF08006.11 EON33311.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Metal_resist PF13801.6 EON33311.1 - 0.36 11.0 3.6 1 9.6 3.6 1.7 1 0 0 1 1 1 0 Heavy-metal resistance YrhK PF14145.6 EON33312.1 - 0.029 14.2 0.4 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 YrhK-like protein DUF2768 PF10966.8 EON33312.1 - 0.47 10.9 6.6 18 5.8 2.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) DUF4149 PF13664.6 EON33312.1 - 3.2 8.1 8.3 0.6 10.5 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4149) Abhydrolase_6 PF12697.7 EON33314.1 - 1.7e-13 51.7 9.7 2.1e-13 51.4 9.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON33314.1 - 1.2e-11 44.8 0.0 1.5e-10 41.2 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON33314.1 - 9.3e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 EON33314.1 - 0.0015 18.0 0.0 0.0037 16.8 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Thioesterase PF00975.20 EON33314.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain COesterase PF00135.28 EON33315.1 - 6.1e-102 342.1 0.0 1.1e-101 341.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EON33315.1 - 3.5e-12 46.6 0.4 8.6e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON33315.1 - 0.00017 21.2 0.0 0.00046 19.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EON33315.1 - 0.00031 19.7 0.0 0.00074 18.5 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.20 EON33315.1 - 0.0013 18.5 1.0 0.014 15.1 1.1 2.0 1 1 0 1 1 1 1 Putative esterase LamB_YcsF PF03746.16 EON33316.1 - 3.8e-91 305.0 1.4 4.3e-91 304.8 1.4 1.0 1 0 0 1 1 1 1 LamB/YcsF family SpoU_methylase PF00588.19 EON33317.1 - 1.3e-36 125.9 0.0 2.2e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EON33317.1 - 3.6e-15 56.0 0.0 7.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding TSNR_N PF04705.12 EON33317.1 - 0.0072 16.4 0.1 0.11 12.6 0.0 2.6 2 1 0 2 2 2 1 Thiostrepton-resistance methylase, N terminus tRNA-synt_1e PF01406.19 EON33318.1 - 1.5e-118 395.6 0.0 1.8e-118 395.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EON33318.1 - 1.7e-13 50.1 0.0 4.8e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EON33318.1 - 8.4e-10 39.0 0.1 2.1e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 EON33318.1 - 4.9e-07 28.4 0.0 0.00065 18.1 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EON33318.1 - 1.6e-05 24.0 0.0 0.04 12.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) Condensation PF00668.20 EON33319.1 - 0.24 10.0 0.0 0.27 9.8 0.0 1.3 1 1 0 1 1 1 0 Condensation domain Condensation PF00668.20 EON33320.1 - 2.3e-07 29.9 0.0 8.9e-07 27.9 0.0 1.7 1 1 0 1 1 1 1 Condensation domain Condensation PF00668.20 EON33321.1 - 2.1e-17 63.0 0.0 5.2e-17 61.7 0.0 1.6 1 1 0 1 1 1 1 Condensation domain Esterase PF00756.20 EON33322.1 - 1.5e-35 123.0 0.0 3.2e-35 122.0 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EON33322.1 - 0.0021 17.6 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase UDPGT PF00201.18 EON33324.1 - 0.32 9.7 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase YgbB PF02542.16 EON33325.1 - 5.8e-47 159.8 0.0 6.5e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 YgbB family IspD PF01128.19 EON33326.1 - 1.6e-58 198.1 4.4 1.8e-58 197.9 4.4 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EON33326.1 - 3.7e-12 46.9 7.2 4.1e-12 46.8 6.2 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain CarD_CdnL_TRCF PF02559.16 EON33327.1 - 1.5e-07 32.0 0.0 2.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 CarD-like/TRCF domain GatB_Yqey PF02637.18 EON33327.1 - 0.033 14.1 0.0 0.089 12.7 0.0 1.6 2 0 0 2 2 2 0 GatB domain ATPase PF06745.13 EON33329.1 - 3e-14 52.9 0.0 2.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 KaiC AAA_25 PF13481.6 EON33329.1 - 2.9e-13 49.8 3.7 1.6e-12 47.4 3.7 2.2 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 EON33329.1 - 7e-11 41.6 6.4 1e-10 41.1 6.4 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 EON33329.1 - 2e-10 40.6 0.5 8.1e-10 38.6 0.1 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 EON33329.1 - 4.5e-08 32.7 0.0 2.1e-05 24.0 0.0 2.7 2 1 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EON33329.1 - 1.4e-06 28.6 0.5 3.9e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Lon_C PF05362.13 EON33329.1 - 1.8e-05 24.4 6.3 2.7e-05 23.8 0.4 2.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA_16 PF13191.6 EON33329.1 - 3.9e-05 24.1 1.1 0.00012 22.5 0.3 2.2 2 1 0 2 2 1 1 AAA ATPase domain Rad51 PF08423.11 EON33329.1 - 0.0004 19.7 0.6 0.17 11.1 0.0 2.6 3 0 0 3 3 3 2 Rad51 RecA PF00154.21 EON33329.1 - 0.00066 19.2 1.4 0.0012 18.3 1.4 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_30 PF13604.6 EON33329.1 - 0.00084 19.1 6.4 0.0013 18.4 3.9 2.4 2 1 0 2 2 2 1 AAA domain GvpD PF07088.11 EON33329.1 - 0.0011 17.7 0.1 0.64 8.6 0.0 2.1 2 0 0 2 2 2 2 GvpD gas vesicle protein AAA PF00004.29 EON33329.1 - 0.005 17.3 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON33329.1 - 0.0084 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EON33329.1 - 0.011 15.4 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EON33329.1 - 0.019 14.7 0.1 0.1 12.4 0.1 2.3 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EON33329.1 - 0.022 15.1 0.3 0.042 14.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EON33329.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 EON33329.1 - 0.06 13.9 0.1 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EON33329.1 - 0.066 13.2 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EON33329.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain HypA PF01155.19 EON33329.1 - 0.078 13.0 0.5 0.21 11.6 0.5 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2075 PF09848.9 EON33329.1 - 0.093 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 EON33329.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EON33329.1 - 0.13 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EON33329.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Zn-ribbon_8 PF09723.10 EON33329.1 - 0.14 12.3 1.7 0.28 11.3 1.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain MMR_HSR1 PF01926.23 EON33329.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EON33329.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain UPF0547 PF10571.9 EON33329.1 - 2.5 8.3 7.5 0.38 10.9 3.6 1.6 2 0 0 2 2 1 0 Uncharacterised protein family UPF0547 Zn_ribbon_SprT PF17283.2 EON33329.1 - 7.1 6.6 6.1 3.9 7.4 0.3 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain 4HBT PF03061.22 EON33330.1 - 4e-10 39.9 0.0 7.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DisA-linker PF10635.9 EON33331.1 - 1.4e-43 148.1 1.3 2.1e-43 147.5 1.3 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller linker region DisA_N PF02457.16 EON33331.1 - 5.5e-26 90.5 0.0 9.1e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding HHH_2 PF12826.7 EON33331.1 - 9.3e-07 28.9 0.2 2.9e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif GSH_synth_ATP PF03917.17 EON33331.1 - 0.014 14.2 0.1 0.022 13.5 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain HHH_5 PF14520.6 EON33331.1 - 0.015 15.9 0.1 0.14 12.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Rogdi_lz PF10259.9 EON33331.1 - 0.21 11.0 0.3 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein DUF4307 PF14155.6 EON33332.1 - 0.043 13.6 0.2 0.084 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Pro_CA PF00484.19 EON33333.1 - 3.4e-37 128.2 0.0 4.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase HhH-GPD PF00730.25 EON33334.1 - 4.6e-14 52.8 0.0 7.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 EON33334.1 - 8.8e-06 25.9 3.8 8.8e-06 25.9 3.8 2.2 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.23 EON33334.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif UPF0259 PF06790.11 EON33335.1 - 0.0015 18.3 11.3 0.0028 17.5 11.3 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0259) DUF4013 PF13197.6 EON33335.1 - 0.058 13.2 28.6 0.1 12.4 9.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) Pex14_N PF04695.13 EON33335.1 - 0.23 12.1 9.3 0.5 11.0 9.3 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GPDPase_memb PF10110.9 EON33335.1 - 0.51 9.1 16.3 0.24 10.1 4.4 2.4 1 1 1 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Abhydrolase_6 PF12697.7 EON33336.1 - 4.9e-18 66.5 16.3 5.9e-18 66.3 16.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON33336.1 - 2.7e-15 56.7 0.1 6.4e-12 45.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON33336.1 - 1e-06 28.2 0.0 3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EON33336.1 - 0.0035 17.5 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EON33336.1 - 0.0036 17.0 0.1 0.0095 15.6 0.1 1.7 1 1 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 EON33336.1 - 0.019 14.4 0.2 0.042 13.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.14 EON33336.1 - 0.053 12.2 0.0 3.2 6.4 0.0 2.0 2 0 0 2 2 2 0 Ndr family Abhydro_lipase PF04083.16 EON33336.1 - 0.15 11.6 0.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region ABM PF03992.16 EON33337.1 - 4e-17 62.1 0.0 4.9e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LON_substr_bdg PF02190.16 EON33338.1 - 7.9e-17 61.8 0.0 1.4e-16 61.0 0.0 1.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Aldedh PF00171.22 EON33339.1 - 1.5e-160 534.7 0.6 1.7e-160 534.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Inhibitor_I48 PF10467.9 EON33339.1 - 0.0046 16.8 0.0 0.0096 15.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor clitocypin Semialdhyde_dh PF01118.24 EON33339.1 - 0.093 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ABC_tran PF00005.27 EON33340.1 - 6e-26 91.6 0.0 9e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON33340.1 - 2.3e-08 34.2 0.1 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON33340.1 - 4.3e-05 24.0 0.3 0.00013 22.4 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON33340.1 - 6.9e-05 22.5 0.9 0.00013 21.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_membrane PF00664.23 EON33340.1 - 0.0002 21.1 0.4 0.00046 19.9 0.3 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EON33340.1 - 0.00054 19.5 0.0 0.055 12.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 EON33340.1 - 0.0022 18.0 0.1 0.0049 16.8 0.1 1.6 1 0 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 EON33340.1 - 0.0052 16.7 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EON33340.1 - 0.0059 16.9 0.8 0.035 14.4 0.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EON33340.1 - 0.016 15.7 0.0 0.023 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON33340.1 - 0.034 14.4 1.0 0.28 11.4 0.6 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EON33340.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EON33340.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rad17 PF03215.15 EON33340.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 EON33340.1 - 0.22 11.1 0.2 0.36 10.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.9 EON33340.1 - 0.26 10.4 0.0 0.45 9.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF4781 PF16013.5 EON33340.1 - 6.6 5.4 8.2 12 4.6 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) ABC_tran PF00005.27 EON33341.1 - 2.7e-28 99.2 0.0 4.2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EON33341.1 - 2.8e-18 66.5 1.3 1.7e-17 64.0 1.3 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON33341.1 - 3.4e-08 33.2 0.0 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON33341.1 - 2.1e-07 31.1 0.1 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON33341.1 - 2.4e-06 27.2 0.2 6.1e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON33341.1 - 0.00034 21.1 0.2 0.0011 19.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EON33341.1 - 0.00043 20.8 0.1 0.00068 20.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON33341.1 - 0.006 16.3 1.7 0.0085 15.8 0.1 2.1 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 EON33341.1 - 0.0095 15.0 0.1 0.023 13.8 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EON33341.1 - 0.011 16.0 0.0 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON33341.1 - 0.013 15.4 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 EON33341.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 EON33341.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EON33341.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EON33341.1 - 0.16 12.1 2.7 0.35 11.0 0.4 2.6 2 1 0 2 2 2 0 AAA domain MukB PF04310.12 EON33341.1 - 0.17 11.7 0.2 0.43 10.3 0.2 1.6 1 0 0 1 1 1 0 MukB N-terminal DUF4350 PF14258.6 EON33341.1 - 0.17 12.3 3.6 0.18 12.3 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) DUF4381 PF14316.6 EON33341.1 - 5.3 7.3 6.0 18 5.5 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Cyt_bd_oxida_II PF02322.15 EON33342.1 - 4.9e-111 370.9 30.6 5.6e-111 370.7 30.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF2070 PF09843.9 EON33342.1 - 7.7 4.7 9.3 15 3.7 9.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyt_bd_oxida_I PF01654.17 EON33343.1 - 9.2e-159 528.5 12.8 1.5e-158 527.9 12.8 1.3 1 1 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cation_efflux PF01545.21 EON33343.1 - 0.16 11.7 9.6 0.022 14.5 1.6 2.8 2 1 1 3 3 3 0 Cation efflux family VKOR PF07884.14 EON33343.1 - 1.2 9.3 8.9 0.24 11.6 1.2 3.1 3 0 0 3 3 3 0 Vitamin K epoxide reductase family Aminotran_4 PF01063.19 EON33344.1 - 6.6e-44 150.4 0.0 7.8e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV GCV_T PF01571.21 EON33345.1 - 2.4e-19 69.7 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain MOSC PF03473.17 EON33346.1 - 7.9e-21 74.5 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain DUF3073 PF11273.8 EON33347.1 - 9.3e-22 77.5 0.1 1.1e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3073) DUF3846 PF12957.7 EON33347.1 - 0.0096 16.2 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) Tho1_MOS11_C PF18592.1 EON33347.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain AIRS_C PF02769.22 EON33348.1 - 7.9e-32 110.5 0.1 1.7e-31 109.5 0.1 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EON33348.1 - 1.6e-16 60.7 1.9 2.8e-16 59.9 1.9 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GATase_6 PF13522.6 EON33349.1 - 2e-16 60.4 0.1 4.1e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EON33349.1 - 7.8e-16 58.1 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.21 EON33349.1 - 1.2e-09 37.4 0.0 5e-05 22.2 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II Pribosyltran PF00156.27 EON33349.1 - 5.5e-08 32.5 0.1 9.9e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EON33349.1 - 0.0011 17.9 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 EON33349.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase SCP_3 PF17844.1 EON33350.1 - 1.3e-40 137.0 0.3 1.6e-40 136.8 0.3 1.1 1 0 0 1 1 1 1 Bacterial SCP ortholog GCS2 PF04107.13 EON33351.1 - 8.8e-08 31.8 0.1 0.00021 20.7 0.0 2.3 2 0 0 2 2 2 2 Glutamate-cysteine ligase family 2(GCS2) Ribosomal_L36 PF00444.18 EON33352.1 - 1.3e-16 60.5 1.0 1.4e-16 60.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 DapB_N PF01113.20 EON33353.1 - 3.4e-05 24.0 0.0 7.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDPD PF03009.17 EON33354.1 - 9.7e-08 32.0 0.0 2.4e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EON33354.1 - 0.00027 21.3 0.1 0.00053 20.3 0.1 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2752 PF10825.8 EON33355.1 - 4.7e-18 65.0 4.1 4.7e-18 65.0 4.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2752) DUF3949 PF13133.6 EON33355.1 - 0.16 12.5 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) DUF983 PF06170.12 EON33355.1 - 0.5 10.8 7.3 1.1 9.7 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) DUF347 PF03988.12 EON33355.1 - 6.7 7.0 8.1 22 5.3 1.4 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CD225 PF04505.12 EON33356.1 - 4.2e-24 84.5 4.2 4.2e-24 84.5 4.2 1.5 1 1 0 1 1 1 1 Interferon-induced transmembrane protein DUF898 PF05987.13 EON33356.1 - 0.017 14.2 3.4 0.022 13.8 3.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4064 PF13273.6 EON33356.1 - 0.021 15.1 3.5 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) ODV-E18 PF10717.9 EON33356.1 - 0.16 11.9 0.7 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Orf78 PF06024.12 EON33356.1 - 0.26 11.6 5.0 0.06 13.6 1.4 1.7 1 1 1 2 2 2 0 Orf78 (ac78) Insulin_TMD PF17870.1 EON33356.1 - 0.35 11.0 6.3 0.42 10.7 2.5 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment RhodobacterPufX PF11511.8 EON33356.1 - 1.5 8.4 3.8 3.7 7.2 3.8 1.6 1 0 0 1 1 1 0 Intrinsic membrane protein PufX AIRS_C PF02769.22 EON33357.1 - 1.1e-54 184.8 1.9 1.2e-33 116.4 0.3 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EON33357.1 - 4.7e-48 161.8 5.3 4.4e-23 81.8 0.2 2.9 3 0 0 3 3 3 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 EON33357.1 - 1.5e-16 60.6 0.0 3.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF5605 PF18310.1 EON33357.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) AAA PF00004.29 EON33358.1 - 3e-16 60.0 0.0 5.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EON33358.1 - 3e-12 46.5 1.6 1.1e-11 44.7 0.5 2.5 2 0 0 2 2 2 1 AAA lid domain TPR_2 PF07719.17 EON33358.1 - 1e-05 25.2 0.3 0.015 15.3 0.1 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EON33358.1 - 2.1e-05 24.4 0.0 0.015 15.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 EON33358.1 - 0.00016 22.0 0.3 0.017 15.4 0.3 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON33358.1 - 0.0004 20.2 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EON33358.1 - 0.00048 20.7 0.0 0.0012 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EON33358.1 - 0.00056 19.4 0.1 0.024 14.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TPR_14 PF13428.6 EON33358.1 - 0.00085 20.0 6.8 1.9 9.5 0.7 4.7 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 EON33358.1 - 0.0017 18.8 0.8 0.0073 16.7 0.2 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 EON33358.1 - 0.0023 18.1 0.1 0.0078 16.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EON33358.1 - 0.0026 17.5 0.1 0.0069 16.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.6 EON33358.1 - 0.0047 17.5 0.3 0.16 12.6 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON33358.1 - 0.0052 17.1 0.1 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EON33358.1 - 0.0075 16.7 0.5 54 4.4 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SKI PF01202.22 EON33358.1 - 0.011 15.8 0.1 0.04 14.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_5 PF07728.14 EON33358.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 EON33358.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Torsin tRNA_lig_kinase PF08303.11 EON33358.1 - 0.027 14.6 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_28 PF13521.6 EON33358.1 - 0.029 14.6 0.7 0.095 12.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EON33358.1 - 0.03 14.6 0.1 0.073 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EON33358.1 - 0.05 14.0 0.1 0.19 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 EON33358.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TPR_16 PF13432.6 EON33358.1 - 0.068 13.8 13.2 0.38 11.4 1.3 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Rad17 PF03215.15 EON33358.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 EON33358.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 NTPase DUF1180 PF06679.12 EON33359.1 - 0.046 14.1 6.2 0.056 13.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HdeA PF06411.11 EON33359.1 - 0.053 13.7 2.5 0.09 13.0 0.0 2.5 2 2 1 3 3 3 0 HdeA/HdeB family DUF3917 PF13055.6 EON33360.1 - 0.038 14.4 0.1 0.038 14.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3917) Filo_glycop PF01611.16 EON33360.1 - 0.17 10.8 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein SirB PF04247.12 EON33360.1 - 2.1 8.5 7.1 0.084 13.0 1.2 1.6 3 0 0 3 3 3 0 Invasion gene expression up-regulator, SirB Inositol_P PF00459.25 EON33361.1 - 1.8e-28 99.9 0.1 3.4e-28 98.9 0.1 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family APS_kinase PF01583.20 EON33362.1 - 7.3e-67 224.2 0.0 1.3e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 EON33362.1 - 1.5e-41 142.1 0.0 2.1e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EON33362.1 - 2.3e-07 30.9 0.1 0.0001 22.4 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EON33362.1 - 4e-07 30.3 0.0 3.2e-06 27.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain GTP_EFTU_D2 PF03144.25 EON33362.1 - 0.00013 22.3 0.0 0.00033 21.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AAA_18 PF13238.6 EON33362.1 - 0.00016 22.2 0.0 0.00037 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON33362.1 - 0.0025 17.7 0.0 3.5 7.5 0.0 3.2 2 1 1 3 3 3 1 RsgA GTPase KTI12 PF08433.10 EON33362.1 - 0.0041 16.6 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EON33362.1 - 0.0066 16.8 0.0 0.02 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EON33362.1 - 0.0078 15.9 0.8 0.16 11.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 EON33362.1 - 0.098 12.3 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 EON33362.1 - 0.11 12.0 0.0 9 5.7 0.0 2.9 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit Zot PF05707.12 EON33362.1 - 0.13 11.9 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_22 PF13401.6 EON33362.1 - 0.13 12.5 0.0 0.66 10.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EON33362.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EON33362.1 - 0.18 12.3 0.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EON33362.1 - 0.21 11.3 0.0 0.67 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain PAPS_reduct PF01507.19 EON33363.1 - 2.3e-48 164.5 0.0 2.9e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EON33363.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 EON33363.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC HTH_IclR PF09339.10 EON33364.1 - 2e-12 46.7 0.1 6e-12 45.2 0.1 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON33364.1 - 0.00011 22.0 2.7 0.00023 21.0 0.1 2.8 3 0 0 3 3 3 1 MarR family IclR PF01614.18 EON33364.1 - 0.00011 22.0 0.2 0.00052 19.9 0.1 2.0 1 1 0 2 2 2 1 Bacterial transcriptional regulator HTH_24 PF13412.6 EON33364.1 - 0.0015 18.1 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 EON33364.1 - 0.0063 17.0 0.0 0.027 15.0 0.0 2.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF977 PF06163.11 EON33364.1 - 0.0069 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) MarR PF01047.22 EON33364.1 - 0.0069 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 MarR family AbiEi_4 PF13338.6 EON33364.1 - 0.011 15.8 1.3 0.044 13.9 0.0 2.6 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 EON33364.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RP-C PF03428.13 EON33364.1 - 0.02 14.6 0.5 0.059 13.0 0.0 2.0 2 0 0 2 2 2 0 Replication protein C N-terminal domain HTH_11 PF08279.12 EON33364.1 - 0.041 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain EAP30 PF04157.16 EON33364.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_5 PF01022.20 EON33364.1 - 0.12 12.3 0.1 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DprA_WH PF17782.1 EON33364.1 - 9.6 6.4 7.1 1.6 8.9 2.0 2.4 3 0 0 3 3 3 0 DprA winged helix domain ECH_1 PF00378.20 EON33366.1 - 2.9e-38 131.6 0.1 6.9e-36 123.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON33366.1 - 1.2e-17 64.4 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_M PF02770.19 EON33367.1 - 2.7e-17 62.8 0.0 5.5e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON33367.1 - 7e-17 62.0 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33367.1 - 4.4e-16 59.5 0.0 9.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Enolase_like_N PF18374.1 EON33367.1 - 0.075 12.4 0.1 4.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Enolase N-terminal domain-like Acyl-CoA_dh_1 PF00441.24 EON33368.1 - 1.2e-24 87.2 3.8 1.2e-24 87.2 3.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33368.1 - 8.1e-09 36.1 0.0 3e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON33368.1 - 1.4e-08 35.1 5.8 1.4e-08 35.1 5.8 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EON33369.1 - 1.1e-27 97.1 4.6 2.9e-27 95.7 3.9 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33369.1 - 3.5e-15 56.7 0.9 7.8e-15 55.5 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON33369.1 - 2.5e-11 44.0 5.0 2.5e-11 44.0 5.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Arm-DNA-bind_3 PF13356.6 EON33369.1 - 0.024 15.0 0.4 0.049 14.0 0.4 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain TPR_19 PF14559.6 EON33369.1 - 0.16 12.5 2.1 18 5.9 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CHASE8 PF17152.4 EON33369.1 - 0.2 11.9 2.3 0.29 11.4 0.9 1.9 2 0 0 2 2 2 0 Periplasmic sensor domain TMP_2 PF06791.13 EON33369.1 - 0.44 10.2 6.4 0.088 12.5 0.7 2.3 3 0 0 3 3 3 0 Prophage tail length tape measure protein FCD PF07729.12 EON33369.1 - 0.49 10.8 6.8 0.43 11.0 2.6 2.6 2 1 0 2 2 2 0 FCD domain DUF1211 PF06736.11 EON33370.1 - 1.1e-22 80.2 4.1 1.1e-22 80.2 4.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1211) 7TMR-DISM_7TM PF07695.11 EON33370.1 - 1 9.2 9.7 5.3 6.9 9.6 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling Abhydrolase_9_N PF15420.6 EON33370.1 - 4.2 7.3 10.9 4 7.4 4.1 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus SLATT_1 PF18181.1 EON33370.1 - 8.2 6.4 10.5 11 5.9 1.9 2.9 2 1 2 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 Sulfotransfer_3 PF13469.6 EON33371.1 - 9.3e-59 199.4 0.5 1.3e-58 198.9 0.5 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EON33371.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 EON33371.1 - 1.3e-06 28.4 0.0 0.00069 19.5 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain adh_short_C2 PF13561.6 EON33372.1 - 1.2e-53 182.1 0.2 1.8e-53 181.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON33372.1 - 4.4e-42 143.8 0.3 5.8e-42 143.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON33372.1 - 6.4e-07 29.5 0.4 8.5e-07 29.1 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF1214 PF06742.11 EON33373.1 - 0.0009 19.7 0.0 0.23 11.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) Flavin_Reduct PF01613.18 EON33374.1 - 5e-38 130.6 0.0 5.9e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EON33374.1 - 2.5e-05 24.1 0.0 3.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Glyoxalase PF00903.25 EON33375.1 - 2.2e-24 86.1 0.0 5.5e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EON33375.1 - 5.3e-05 24.0 0.1 0.0011 19.8 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase-like domain Acyl-CoA_dh_2 PF08028.11 EON33376.1 - 6.7e-39 133.2 5.3 6.7e-39 133.2 5.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33376.1 - 2.4e-05 25.0 0.1 9.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON33376.1 - 0.00021 21.5 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON33376.1 - 0.033 14.4 2.0 0.084 13.1 2.0 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Rieske PF00355.26 EON33377.1 - 1.1e-16 60.5 0.0 1.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NLPC_P60 PF00877.19 EON33379.1 - 2.8e-21 75.5 0.0 3.6e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family CHAP PF05257.16 EON33379.1 - 0.00021 21.8 0.4 0.00035 21.1 0.4 1.4 1 0 0 1 1 1 1 CHAP domain Peptidase_C92 PF05708.12 EON33379.1 - 0.089 12.9 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Amidase_5 PF05382.13 EON33379.1 - 0.089 12.7 0.2 0.52 10.2 0.2 2.0 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase FtsX PF02687.21 EON33380.1 - 0.00066 20.1 5.7 0.00066 20.1 5.7 1.8 2 0 0 2 2 2 1 FtsX-like permease family DUF4131 PF13567.6 EON33380.1 - 0.039 13.6 7.9 0.069 12.8 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF347 PF03988.12 EON33380.1 - 0.059 13.6 2.6 0.059 13.6 2.6 3.8 4 0 0 4 4 4 0 Repeat of Unknown Function (DUF347) DUF2104 PF09877.9 EON33380.1 - 0.54 10.6 5.8 11 6.3 1.5 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2104) ATPase_gene1 PF09527.10 EON33380.1 - 5.2 7.3 12.0 0.38 10.9 2.0 2.7 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Glyoxalase_6 PF18029.1 EON33381.1 - 5.5e-16 59.3 0.0 1.8e-07 31.9 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 EON33381.1 - 5.5e-13 49.2 0.0 7.5e-08 32.6 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EON33381.1 - 0.00011 22.4 0.1 0.5 10.7 0.0 3.5 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SLAC1 PF03595.17 EON33382.1 - 1.8e-59 201.7 52.2 2e-59 201.5 52.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel LysR_substrate PF03466.20 EON33383.1 - 7.6e-42 143.0 11.4 7.6e-42 143.0 11.4 1.9 1 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EON33383.1 - 1.4e-18 66.5 2.8 3.7e-18 65.2 2.8 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 EON33383.1 - 4.8e-08 32.3 0.0 2.2e-07 30.2 0.0 1.9 1 1 1 2 2 2 1 PBP superfamily domain HTH_30 PF13556.6 EON33383.1 - 0.00043 20.0 0.2 0.0012 18.6 0.2 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain PBP_like_2 PF12849.7 EON33383.1 - 0.0067 16.1 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 PBP superfamily domain HTH_AsnC-type PF13404.6 EON33383.1 - 0.023 14.5 0.1 0.06 13.2 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain P22_Cro PF14549.6 EON33383.1 - 0.082 12.8 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HMGL-like PF00682.19 EON33384.1 - 4.5e-48 164.1 2.8 5.9e-48 163.7 2.8 1.1 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.11 EON33384.1 - 6e-30 102.6 0.9 1.8e-29 101.1 0.1 2.1 2 0 0 2 2 2 1 DmpG-like communication domain DUF442 PF04273.13 EON33384.1 - 0.039 14.0 0.2 18 5.5 0.0 2.9 3 0 0 3 3 3 0 Putative phosphatase (DUF442) AcetDehyd-dimer PF09290.11 EON33385.1 - 9e-63 210.6 0.2 1.3e-62 210.0 0.2 1.2 1 0 0 1 1 1 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Semialdhyde_dh PF01118.24 EON33385.1 - 4.9e-11 43.1 0.0 2.3e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EON33385.1 - 0.019 15.2 0.1 0.089 13.1 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EON33385.1 - 0.064 14.1 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EON33385.1 - 0.076 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EON33385.1 - 0.097 12.9 0.0 0.32 11.3 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAA_hydrolase PF01557.18 EON33386.1 - 3.9e-13 49.6 0.0 4.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ECH_1 PF00378.20 EON33387.1 - 7.8e-25 87.6 0.3 9.9e-25 87.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON33387.1 - 6.6e-23 81.7 0.0 7.8e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_N PF02771.16 EON33388.1 - 5e-24 85.1 0.0 1.2e-23 84.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON33388.1 - 3.5e-19 68.8 0.0 6.6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON33388.1 - 1.8e-07 31.5 0.4 2e-06 28.1 0.4 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EON33389.1 - 2.3e-19 70.1 13.3 5.1e-19 69.0 13.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON33389.1 - 2.6e-06 27.5 0.0 6.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON33389.1 - 3.2e-05 24.6 0.1 3.2e-05 24.6 0.1 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Hpt PF01627.23 EON33389.1 - 0.7 10.2 4.7 1 9.7 0.9 2.7 2 1 0 2 2 2 0 Hpt domain FAD_binding_2 PF00890.24 EON33390.1 - 4e-93 312.8 1.0 4.7e-93 312.5 1.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EON33390.1 - 2.9e-14 53.3 3.1 1.9e-11 44.0 1.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 EON33390.1 - 4.7e-12 46.2 7.5 2.9e-11 43.6 7.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON33390.1 - 9.5e-09 34.9 0.3 1e-06 28.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON33390.1 - 1.1e-08 34.2 0.1 1.3e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EON33390.1 - 3e-07 29.9 1.0 5.9e-06 25.6 0.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EON33390.1 - 1.9e-06 27.3 4.4 3.3e-06 26.5 0.4 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 EON33390.1 - 1.1e-05 25.6 0.8 3.7e-05 23.9 0.8 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EON33390.1 - 0.00011 21.5 0.1 0.00024 20.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EON33390.1 - 0.00026 21.5 0.1 0.22 12.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON33390.1 - 0.00049 19.5 0.2 0.0014 18.0 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EON33390.1 - 0.00085 18.5 0.2 0.0015 17.6 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EON33390.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MaoC_dehydratas PF01575.19 EON33391.1 - 2.2e-28 98.3 0.0 4.1e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON33391.1 - 6.2e-19 68.4 0.0 1.7e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MFS_1 PF07690.16 EON33394.1 - 8.3e-41 140.1 58.6 9.1e-41 139.9 55.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON33394.1 - 0.035 13.0 32.1 0.016 14.1 12.8 3.4 1 1 1 3 3 3 0 Sugar (and other) transporter OATP PF03137.20 EON33394.1 - 0.26 9.5 14.6 0.033 12.5 1.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ArsB PF02040.15 EON33395.1 - 4.5e-19 69.1 21.0 7.5e-19 68.3 21.0 1.4 1 1 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 EON33395.1 - 1.7e-13 50.4 51.1 1.7e-13 50.4 51.1 2.1 1 1 1 2 2 2 1 Citrate transporter GTA_holin_3TM PF11351.8 EON33395.1 - 1.2 9.7 8.1 0.072 13.6 0.9 2.7 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release MFS_1 PF07690.16 EON33396.1 - 5e-36 124.4 68.4 5.6e-31 107.7 48.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON33396.1 - 0.46 9.3 15.4 0.0036 16.2 5.0 2.7 2 2 1 3 3 3 0 MFS_1 like family LysE PF01810.18 EON33397.1 - 5.9e-31 107.4 9.0 7.3e-31 107.1 9.0 1.1 1 0 0 1 1 1 1 LysE type translocator Mntp PF02659.15 EON33397.1 - 0.0072 16.1 7.0 0.012 15.4 2.2 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump MerC PF03203.14 EON33397.1 - 3.8 8.0 11.6 0.39 11.2 1.2 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein AMP-binding PF00501.28 EON33398.1 - 2.5e-56 191.1 0.0 3.2e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON33398.1 - 2.5e-19 70.0 1.7 2.5e-19 70.0 1.7 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 EON33399.1 - 2.9e-09 36.7 1.2 6.6e-09 35.5 1.2 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain MaoC_dehydratas PF01575.19 EON33400.1 - 4.8e-05 22.9 0.2 6.2e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON33400.1 - 0.09 12.9 0.1 6.5 6.9 0.0 2.2 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase HlyD PF00529.20 EON33400.1 - 0.12 12.3 0.9 0.14 12.1 0.9 1.4 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS OB_aCoA_assoc PF01796.17 EON33401.1 - 5.2e-20 71.2 4.5 1.1e-19 70.1 4.5 1.6 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated MaoC_dehydrat_N PF13452.6 EON33401.1 - 2.7e-16 59.9 0.0 6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF35_N PF12172.8 EON33401.1 - 0.013 15.4 1.1 0.032 14.1 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MaoC_dehydratas PF01575.19 EON33401.1 - 0.019 14.6 0.1 0.04 13.5 0.1 1.6 1 1 0 1 1 1 0 MaoC like domain Acyl-CoA_dh_N PF02771.16 EON33402.1 - 4.1e-24 85.4 0.0 1e-23 84.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON33402.1 - 6.4e-22 77.6 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON33402.1 - 1.4e-19 70.8 0.6 2.1e-19 70.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EON33402.1 - 0.19 12.3 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EON33403.1 - 5.4e-14 52.7 0.2 1e-13 51.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33403.1 - 0.015 15.9 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON33404.1 - 3e-25 89.2 14.0 5.6e-13 49.4 1.4 3.3 2 2 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON33404.1 - 4.2e-20 71.8 0.0 1e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON33404.1 - 8.9e-18 65.0 0.1 1.8e-07 31.8 0.0 3.8 4 0 0 4 4 4 2 Acyl-CoA dehydrogenase, N-terminal domain ArgoMid PF16487.5 EON33404.1 - 0.15 12.4 0.1 0.41 10.9 0.1 1.7 1 0 0 1 1 1 0 Mid domain of argonaute TetR_C_20 PF17925.1 EON33405.1 - 4.8e-37 126.5 4.1 4.8e-37 126.5 4.1 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON33405.1 - 1.1e-15 57.1 0.1 2e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 EON33405.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Esterase PF00756.20 EON33406.1 - 3.9e-38 131.5 0.0 4.9e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Putative esterase MaoC_dehydratas PF01575.19 EON33407.1 - 2e-15 56.4 0.0 2.6e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON33407.1 - 2.7e-05 24.3 0.0 4.3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 EON33407.1 - 0.03 14.7 0.0 0.082 13.3 0.0 1.8 1 1 0 1 1 1 0 Thioesterase superfamily MFS_3 PF05977.13 EON33408.1 - 3.9e-64 216.9 41.2 4.8e-64 216.6 41.2 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EON33408.1 - 7.8e-28 97.4 51.4 1.2e-20 73.7 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2236 PF09995.9 EON33409.1 - 7.9e-43 147.3 3.7 1e-42 146.9 3.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) 3HCDH_N PF02737.18 EON33410.1 - 2.6e-61 206.6 1.6 3.8e-61 206.1 1.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EON33410.1 - 1.4e-34 118.6 0.0 3.4e-34 117.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain F420_oxidored PF03807.17 EON33410.1 - 2e-05 25.1 2.9 3.5e-05 24.3 1.7 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 EON33410.1 - 0.00032 20.4 0.2 0.00056 19.6 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 EON33410.1 - 0.00033 20.8 0.9 0.0006 20.0 0.8 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 EON33410.1 - 0.00078 20.0 1.0 0.0018 18.8 1.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON33410.1 - 0.0015 17.8 0.8 0.0025 17.1 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EON33410.1 - 0.0031 17.9 0.4 0.0054 17.1 0.4 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EON33410.1 - 0.0035 17.6 1.3 0.0074 16.5 0.9 1.8 1 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EON33410.1 - 0.0049 16.8 0.4 0.0092 16.0 0.3 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 EON33410.1 - 0.017 15.4 1.8 0.026 14.8 0.5 1.8 1 1 1 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EON33410.1 - 0.045 13.1 0.3 0.08 12.3 0.3 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON33410.1 - 0.051 12.8 0.7 0.095 11.9 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain DFP PF04127.15 EON33410.1 - 0.054 13.3 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_8 PF13450.6 EON33410.1 - 0.085 13.1 0.5 0.18 12.1 0.5 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Methyltransf_12 PF08242.12 EON33410.1 - 0.14 12.9 0.1 0.26 12.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EON33410.1 - 0.21 11.2 2.4 0.27 10.8 1.3 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HHV-1_VABD PF16852.5 EON33411.1 - 5 7.2 6.3 1.2 9.2 1.5 2.1 1 1 1 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain MazG PF03819.17 EON33412.1 - 6.2e-23 80.8 0.0 1e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 EON33412.1 - 5.6e-05 23.5 0.1 0.00015 22.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase DUF4805 PF16063.5 EON33412.1 - 0.0031 16.9 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4805) Amidohydro_1 PF01979.20 EON33413.1 - 3.2e-55 187.8 0.0 3.7e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON33413.1 - 3.4e-12 46.6 6.0 2.4e-08 33.9 3.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family 2OG-FeII_Oxy PF03171.20 EON33414.1 - 2.1e-20 73.1 0.0 3.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EON33414.1 - 4.2e-19 69.4 0.0 7.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PipA PF07108.11 EON33414.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 PipA protein ABC_tran PF00005.27 EON33417.1 - 1.2e-28 100.3 0.0 2.1e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EON33417.1 - 9.2e-06 26.1 0.1 1.4e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON33417.1 - 0.00013 22.2 0.0 0.00031 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON33417.1 - 0.0023 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EON33417.1 - 0.0036 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EON33417.1 - 0.01 16.1 0.1 0.033 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EON33417.1 - 0.012 15.5 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EON33417.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 EON33417.1 - 0.017 15.2 0.1 0.03 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EON33417.1 - 0.018 14.9 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 EON33417.1 - 0.022 14.3 0.1 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EON33417.1 - 0.027 13.9 0.0 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 EON33417.1 - 0.029 14.4 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EON33417.1 - 0.035 14.5 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EON33417.1 - 0.04 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EON33417.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EON33417.1 - 0.045 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON33417.1 - 0.047 13.9 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EON33417.1 - 0.071 13.1 0.2 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EON33417.1 - 0.096 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EON33417.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EON33417.1 - 0.24 11.8 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase BPD_transp_1 PF00528.22 EON33418.1 - 7.7e-17 61.6 15.9 7.7e-17 61.6 15.9 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DIOX_N PF14226.6 EON33419.1 - 3.8e-26 92.1 0.0 5.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EON33419.1 - 9.3e-17 61.4 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FCD PF07729.12 EON33420.1 - 1e-20 74.4 12.3 1.6e-20 73.8 12.3 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON33420.1 - 7.4e-15 54.4 1.2 2.8e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 EON33420.1 - 0.0021 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EON33420.1 - 0.0049 16.4 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON33420.1 - 0.016 15.0 0.1 0.016 15.0 0.1 2.4 3 0 0 3 3 3 0 MarR family HTH_11 PF08279.12 EON33420.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 HTH domain Sulfatase PF00884.23 EON33421.1 - 1.8e-41 142.5 0.0 3.6e-39 135.0 0.0 2.1 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EON33421.1 - 1.2e-08 35.1 0.0 4.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EON33421.1 - 4.4e-08 33.1 0.3 5.6e-06 26.2 0.3 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EON33421.1 - 0.06 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 EON33421.1 - 0.17 11.8 0.0 0.89 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function Sulphotransf PF09037.10 EON33422.1 - 9.3e-78 261.1 0.1 1.1e-77 260.9 0.1 1.0 1 0 0 1 1 1 1 Stf0 sulphotransferase Sulfotransfer_3 PF13469.6 EON33422.1 - 2.4e-06 28.1 0.1 0.0073 16.7 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family PAPS_reduct PF01507.19 EON33423.1 - 1.2e-42 145.9 0.0 1.4e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EON33423.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family APS_kinase PF01583.20 EON33424.1 - 7.7e-66 220.8 0.0 1.4e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 EON33424.1 - 3.8e-38 131.0 0.0 5.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EON33424.1 - 6.8e-08 32.6 0.1 1.1e-05 25.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EON33424.1 - 1.5e-06 28.5 0.4 1.5e-05 25.3 0.2 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 AAA_33 PF13671.6 EON33424.1 - 0.00011 22.3 0.2 0.00038 20.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 EON33424.1 - 0.00018 21.0 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EON33424.1 - 0.00095 19.7 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EON33424.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EON33424.1 - 0.011 16.1 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EON33424.1 - 0.025 14.3 0.0 0.62 9.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 EON33424.1 - 0.034 13.9 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EON33424.1 - 0.042 12.8 0.1 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FGE-sulfatase PF03781.16 EON33425.1 - 5.4e-70 235.9 2.4 6e-70 235.8 2.4 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 SLT_2 PF13406.6 EON33426.1 - 5.9e-12 45.4 3.4 3.6e-09 36.3 1.3 2.9 2 1 1 3 3 3 3 Transglycosylase SLT domain SLT PF01464.20 EON33426.1 - 0.0032 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Enolase_C PF00113.22 EON33427.1 - 2.6e-131 437.2 0.0 3.3e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EON33427.1 - 5.8e-54 181.8 0.0 1.2e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EON33427.1 - 8e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EON33427.1 - 0.011 15.0 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DivIC PF04977.15 EON33428.1 - 3.5e-17 61.9 0.0 3.5e-17 61.9 0.0 1.5 2 0 0 2 2 1 1 Septum formation initiator LapA_dom PF06305.11 EON33428.1 - 0.0092 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain JAKMIP_CC3 PF16034.5 EON33428.1 - 0.018 15.0 1.4 0.027 14.4 1.4 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain ADIP PF11559.8 EON33428.1 - 0.045 13.8 1.1 0.067 13.3 1.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1640 PF07798.11 EON33428.1 - 0.048 13.7 0.9 0.048 13.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) STE3 PF02076.15 EON33428.1 - 0.063 12.5 0.1 0.085 12.1 0.1 1.1 1 0 0 1 1 1 0 Pheromone A receptor FAM176 PF14851.6 EON33428.1 - 0.065 12.9 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 FAM176 family DUF3810 PF12725.7 EON33428.1 - 0.085 12.2 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FtsL PF04999.13 EON33428.1 - 0.11 12.5 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Cell division protein FtsL SPC22 PF04573.12 EON33428.1 - 0.19 11.2 0.2 0.27 10.7 0.2 1.1 1 0 0 1 1 1 0 Signal peptidase subunit V_ATPase_I PF01496.19 EON33428.1 - 0.22 9.4 0.1 0.28 9.0 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF501 PF04417.12 EON33429.1 - 9.2e-32 109.8 0.1 1.5e-21 76.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF501) Ppx-GppA PF02541.16 EON33430.1 - 1.3e-71 241.3 0.0 1.6e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF4395 PF14340.6 EON33432.1 - 4.8e-39 133.7 7.9 5.5e-39 133.5 7.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) DUF2892 PF11127.8 EON33432.1 - 5.8 7.0 18.4 5.7 7.1 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) KIF1B PF12423.8 EON33433.1 - 0.21 12.1 2.5 0.21 12.0 0.2 2.2 1 1 1 2 2 2 0 Kinesin protein 1B FA_desaturase PF00487.24 EON33434.1 - 8.7e-32 110.9 2.6 1.1e-31 110.5 2.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase NAD_binding_1 PF00175.21 EON33435.1 - 2.5e-14 53.8 0.0 5.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON33435.1 - 1.1e-08 35.3 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EON33435.1 - 1.3e-07 31.9 0.0 9.5e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Fer2 PF00111.27 EON33435.1 - 0.071 13.1 0.8 0.14 12.1 0.8 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TetR_N PF00440.23 EON33436.1 - 7.3e-10 38.5 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF664 PF04978.12 EON33436.1 - 0.034 14.5 1.3 0.063 13.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF664) DUF2293 PF10056.9 EON33436.1 - 0.038 14.2 0.7 0.093 13.0 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) SAM_4 PF18017.1 EON33436.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Bac_luciferase PF00296.20 EON33437.1 - 5.4e-77 259.3 10.8 6.6e-77 259.0 10.8 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 EON33438.1 - 2.7e-75 253.7 0.3 3.2e-75 253.5 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Acyl-CoA_dh_2 PF08028.11 EON33439.1 - 2.6e-17 63.3 10.7 2.6e-17 63.3 10.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON33439.1 - 4.3e-11 42.9 0.0 9.8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON33439.1 - 1.2e-09 38.6 3.2 1.2e-09 38.6 3.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33439.1 - 1.1e-07 32.5 1.6 2.5e-07 31.4 0.1 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain ACT_7 PF13840.6 EON33439.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain TerD PF02342.18 EON33440.1 - 2.5e-72 242.3 0.0 7.7e-47 159.2 0.0 2.2 2 0 0 2 2 2 2 TerD domain Big_3_3 PF13750.6 EON33440.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Beta-lactamase2 PF13354.6 EON33441.1 - 0.019 14.6 0.1 3.6 7.1 0.0 2.6 1 1 1 2 2 2 0 Beta-lactamase enzyme family YibE_F PF07907.11 EON33442.1 - 1.8e-64 217.6 29.2 1.8e-64 217.6 29.2 1.7 2 0 0 2 2 2 1 YibE/F-like protein YDG PF18657.1 EON33442.1 - 0.024 14.8 0.1 3.7 7.8 0.0 2.7 2 1 0 2 2 2 0 YDG domain Lipoprotein_9 PF03180.14 EON33443.1 - 1.2e-40 139.1 0.0 1.5e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 NLPA lipoprotein TPR_21 PF09976.9 EON33443.1 - 0.067 12.9 0.3 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain RskA PF10099.9 EON33443.1 - 0.081 13.2 1.9 0.071 13.4 0.6 1.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA BPD_transp_1 PF00528.22 EON33444.1 - 1e-16 61.2 17.1 1e-16 61.2 17.1 1.7 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SP_C-Propep PF08999.10 EON33444.1 - 0.29 11.0 5.2 0.2 11.4 0.8 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide ABC_tran PF00005.27 EON33445.1 - 1.4e-33 116.3 0.0 3.1e-33 115.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EON33445.1 - 7.9e-08 32.5 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NIL PF09383.10 EON33445.1 - 5.1e-07 29.5 0.0 9.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 NIL domain AAA_16 PF13191.6 EON33445.1 - 7.6e-05 23.2 0.5 0.00014 22.3 0.5 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON33445.1 - 8.9e-05 22.8 0.1 0.00084 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EON33445.1 - 0.00034 20.1 0.4 0.12 11.8 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON33445.1 - 0.0017 18.1 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON33445.1 - 0.0037 17.8 0.0 0.006 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON33445.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EON33445.1 - 0.0099 16.3 0.1 0.37 11.2 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EON33445.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EON33445.1 - 0.02 14.5 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EON33445.1 - 0.023 14.4 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EON33445.1 - 0.024 14.4 0.0 0.097 12.4 0.0 2.0 2 1 1 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EON33445.1 - 0.092 12.8 0.2 0.65 10.1 0.2 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 EON33445.1 - 0.16 10.7 0.1 16 4.1 0.0 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class Bac_luciferase PF00296.20 EON33446.1 - 2.7e-55 188.0 7.0 3.7e-55 187.6 7.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF664 PF04978.12 EON33447.1 - 1.1e-16 61.5 0.2 1.3e-15 58.1 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 EON33447.1 - 6.2e-14 52.6 0.1 9.6e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 EON33447.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.7 1 1 0 1 1 1 0 DinB family Bac_luciferase PF00296.20 EON33449.1 - 4e-61 207.1 1.2 4.2e-57 194.0 0.1 2.0 1 1 1 2 2 2 2 Luciferase-like monooxygenase BLOC1_2 PF10046.9 EON33450.1 - 4.5e-05 23.7 0.0 0.029 14.7 0.0 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EON33450.1 - 0.00072 19.8 0.2 0.0031 17.7 0.2 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Collagen_mid PF15984.5 EON33450.1 - 0.0033 17.2 2.1 0.0097 15.7 2.0 1.7 1 1 0 1 1 1 1 Bacterial collagen, middle region DUF1664 PF07889.12 EON33450.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EON33450.1 - 0.013 16.1 0.1 1.3 9.7 0.0 2.4 1 1 1 2 2 2 0 SlyX HrpB7 PF09486.10 EON33450.1 - 0.026 14.9 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4164 PF13747.6 EON33450.1 - 0.032 14.5 0.1 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 EON33450.1 - 0.033 14.2 0.1 0.063 13.3 0.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 EON33450.1 - 0.054 13.2 0.0 4.3 7.0 0.0 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TSKS PF15358.6 EON33450.1 - 0.061 11.7 0.2 0.066 11.6 0.2 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DASH_Duo1 PF08651.10 EON33450.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 WXG100 PF06013.12 EON33450.1 - 0.1 12.8 0.1 8.1 6.8 0.0 2.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 EON33450.1 - 0.11 13.0 0.2 1.3 9.6 0.2 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EON33450.1 - 0.23 11.9 0.0 1.9 9.0 0.0 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Hydrolase_4 PF12146.8 EON33451.1 - 5.2e-72 242.0 0.0 6e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON33451.1 - 8.2e-20 71.5 0.1 3.3e-16 59.7 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON33451.1 - 1.6e-13 51.8 7.3 2e-13 51.5 7.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EON33451.1 - 2.2e-06 27.7 0.0 0.034 14.0 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 EON33451.1 - 6.8e-06 25.8 0.0 0.017 14.7 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EON33451.1 - 0.00012 21.9 0.0 0.0046 16.7 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.20 EON33451.1 - 0.0014 18.4 0.1 0.0036 17.0 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Thioesterase PF00975.20 EON33451.1 - 0.0016 18.6 0.0 0.0036 17.4 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 EON33451.1 - 0.0092 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EON33451.1 - 0.025 14.1 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 EON33451.1 - 0.026 14.4 0.0 0.069 13.0 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase Abhydrolase_3 PF07859.13 EON33451.1 - 0.038 13.8 0.1 0.31 10.9 0.1 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 EON33451.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EON33451.1 - 0.074 12.6 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 EON33451.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 EON33451.1 - 0.082 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.10 EON33451.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF915 PF06028.11 EON33451.1 - 0.32 10.3 0.0 0.64 9.3 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) EXS PF03124.14 EON33452.1 - 0.25 10.6 2.9 0.31 10.3 2.9 1.1 1 0 0 1 1 1 0 EXS family Trp_oprn_chp PF09534.10 EON33452.1 - 1.1 9.1 18.6 2.3 8.0 18.6 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Esterase PF00756.20 EON33453.1 - 2.6e-34 119.0 0.5 4.2e-34 118.3 0.5 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EON33454.1 - 1.4e-25 90.5 0.2 6.6e-24 84.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON33454.1 - 1.3e-16 60.6 0.0 2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON33454.1 - 1.9e-15 58.1 13.2 2.2e-15 57.9 13.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EON33454.1 - 0.0027 17.2 4.1 0.12 11.8 0.2 2.3 1 1 1 2 2 2 2 Esterase PHB depolymerase Ndr PF03096.14 EON33454.1 - 0.007 15.1 0.0 0.0096 14.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 EON33454.1 - 0.071 13.0 0.2 0.11 12.3 0.2 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EON33454.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 EON33454.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Esterase PF00756.20 EON33455.1 - 3.9e-34 118.4 0.0 5.5e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EON33455.1 - 0.046 13.2 0.1 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aldedh PF00171.22 EON33456.1 - 3.7e-151 503.8 2.8 4.1e-151 503.6 2.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Antimicrobial20 PF08256.11 EON33456.1 - 0.17 12.4 2.2 1.7 9.4 0.2 3.3 2 0 0 2 2 2 0 Aurein-like antibiotic peptide Antimicrobial_2 PF08023.12 EON33456.1 - 5.5 7.6 5.7 19 5.9 0.0 3.4 4 0 0 4 4 4 0 Frog antimicrobial peptide ABM PF03992.16 EON33457.1 - 1.9e-16 59.9 0.4 2.3e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MMPL PF03176.15 EON33458.1 - 4.7e-90 301.9 35.3 1.8e-55 188.2 12.6 2.2 2 0 0 2 2 2 2 MMPL family DUF4337 PF14235.6 EON33458.1 - 0.024 14.8 0.9 0.024 14.8 0.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) TetR_C_14 PF17754.1 EON33459.1 - 7.4e-10 38.8 1.8 8.2e-10 38.6 0.2 1.8 2 0 0 2 2 2 1 MftR C-terminal domain TetR_N PF00440.23 EON33459.1 - 1.7e-08 34.1 0.1 3.6e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_31 PF13560.6 EON33459.1 - 0.11 12.8 2.5 3.2 8.2 0.2 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 EON33460.1 - 1.2e-23 84.1 0.2 1.7e-23 83.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON33460.1 - 4.4e-18 66.7 12.3 5.7e-18 66.3 12.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON33460.1 - 1.4e-17 63.8 0.3 9.4e-12 44.7 0.3 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EON33460.1 - 0.00039 20.1 0.7 0.001 18.7 0.7 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 EON33460.1 - 0.00051 20.1 0.0 0.0017 18.5 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 EON33460.1 - 0.022 14.2 0.1 2.5 7.5 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 EON33461.1 - 7e-37 127.2 44.4 1.7e-36 125.9 44.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EON33461.1 - 8.7e-06 24.5 26.2 0.0018 16.9 9.0 3.5 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 EON33461.1 - 0.00015 21.2 12.9 0.00015 21.2 12.9 2.9 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EON33461.1 - 0.00038 19.5 22.7 0.0021 17.0 9.4 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EON33461.1 - 0.064 12.1 0.1 0.064 12.1 0.1 3.9 3 1 1 4 4 4 0 MFS_1 like family Peripla_BP_3 PF13377.6 EON33462.1 - 5.9e-31 108.0 1.4 9.5e-31 107.4 0.6 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EON33462.1 - 7.4e-19 68.2 0.0 9.4e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EON33462.1 - 1.1e-16 61.2 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 EON33462.1 - 1.1e-13 50.8 0.8 1.1e-13 50.8 0.8 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 EON33462.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix TetR_N PF00440.23 EON33462.1 - 0.061 13.1 0.3 0.23 11.3 0.2 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_31 PF13560.6 EON33462.1 - 0.093 13.1 3.4 0.11 12.8 0.1 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain MFS_1 PF07690.16 EON33463.1 - 3e-46 158.0 62.0 6.4e-32 110.8 29.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON33463.1 - 5.2e-08 32.2 35.1 1.8e-06 27.1 11.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter HEV_ORF1 PF02444.16 EON33463.1 - 3.3 8.3 6.3 18 5.9 0.4 3.4 2 1 1 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) FMN_dh PF01070.18 EON33464.1 - 1.6e-126 422.0 0.1 1.9e-126 421.8 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EON33464.1 - 0.015 14.7 2.1 0.023 14.1 2.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.25 EON33464.1 - 0.15 11.0 2.4 2.1 7.3 1.7 2.7 3 1 1 4 4 4 0 IMP dehydrogenase / GMP reductase domain FGGY_C PF02782.16 EON33465.1 - 2.7e-32 112.1 0.0 3.7e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EON33465.1 - 2.5e-22 79.6 0.0 3.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain adh_short_C2 PF13561.6 EON33466.1 - 8e-47 159.7 10.2 2.3e-46 158.3 10.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON33466.1 - 1.8e-41 141.7 5.7 3.2e-41 141.0 5.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Aldolase_II PF00596.21 EON33466.1 - 7.5e-25 87.9 0.1 8.8e-23 81.2 0.0 2.6 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain KR PF08659.10 EON33466.1 - 2e-08 34.3 5.7 4.3e-08 33.3 5.7 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON33466.1 - 0.00028 20.4 0.3 0.00047 19.7 0.3 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON33466.1 - 0.014 14.4 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RhaA PF06134.11 EON33467.1 - 3.4e-09 36.3 0.0 4.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 L-rhamnose isomerase (RhaA) AP_endonuc_2 PF01261.24 EON33467.1 - 0.0006 19.3 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 EON33468.1 - 1.2e-28 100.1 54.9 1.7e-22 79.9 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON33468.1 - 1.2e-28 100.2 35.0 1.1e-26 93.7 35.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EON33468.1 - 0.00026 19.6 3.1 0.00026 19.6 3.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EON33468.1 - 0.025 12.9 3.7 0.11 10.8 0.2 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 EON33468.1 - 0.034 12.7 39.5 0.036 12.6 6.1 3.2 1 1 3 4 4 4 0 MFS/sugar transport protein rhaM PF05336.13 EON33469.1 - 7.6e-27 93.5 0.0 8.3e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF1799 PF08809.11 EON33469.1 - 0.061 13.5 0.2 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) adh_short PF00106.25 EON33470.1 - 1.3e-51 174.9 2.3 1.7e-51 174.5 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON33470.1 - 5.8e-37 127.5 1.9 9e-37 126.9 1.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON33470.1 - 2.9e-09 37.1 1.3 4.8e-09 36.4 1.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON33470.1 - 0.00016 21.2 0.1 0.00023 20.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON33470.1 - 0.034 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON33470.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PAP2_3 PF14378.6 EON33471.1 - 0.014 15.1 2.6 0.014 15.1 2.6 1.0 1 0 0 1 1 1 0 PAP2 superfamily DUF1616 PF07760.11 EON33471.1 - 0.19 11.1 7.3 0.21 10.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Zip PF02535.22 EON33471.1 - 0.2 10.9 4.5 0.22 10.7 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SUKH_6 PF14568.6 EON33472.1 - 6.6e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 EON33472.1 - 0.0033 17.2 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 EON33472.1 - 0.031 14.7 0.0 0.048 14.0 0.0 1.5 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Endonuclea_NS_2 PF13930.6 EON33473.1 - 0.0021 18.2 0.0 0.0021 18.2 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2236 PF09995.9 EON33476.1 - 9e-24 84.9 4.5 1.8e-23 84.0 4.5 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MMPL PF03176.15 EON33477.1 - 5.2e-84 282.0 25.0 4.3e-54 183.7 8.4 2.2 2 0 0 2 2 2 2 MMPL family TetR_C_33 PF13305.6 EON33478.1 - 7.1e-15 55.6 1.7 1.7e-14 54.4 1.7 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON33478.1 - 7.4e-10 38.5 0.0 2.9e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 EON33478.1 - 0.066 13.1 1.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain BaxI_1 PF12811.7 EON33479.1 - 7.5e-84 280.9 17.4 9e-84 280.7 17.4 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like Bax1-I PF01027.20 EON33479.1 - 5.4e-21 75.4 21.9 6.8e-21 75.1 21.9 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CcmH PF03918.14 EON33480.1 - 0.067 12.5 0.5 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Thiolase_N PF00108.23 EON33481.1 - 1e-63 215.2 0.0 3.6e-63 213.4 0.0 1.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON33481.1 - 1.5e-46 157.0 0.6 1.5e-46 157.0 0.6 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON33481.1 - 2.8e-05 23.8 0.4 2.8e-05 23.8 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Lipase_GDSL_2 PF13472.6 EON33482.1 - 7.2e-20 72.1 0.2 1.3e-19 71.3 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON33482.1 - 2.5e-10 40.6 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PGA_cap PF09587.10 EON33482.1 - 0.046 13.2 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap PALP PF00291.25 EON33483.1 - 1.7e-64 218.1 0.3 2.2e-64 217.7 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EON33483.1 - 7.8e-18 64.7 0.1 9.9e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain Phage_Mu_Gp45 PF06890.12 EON33483.1 - 0.055 13.2 0.5 2.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage Mu Gp45 protein Cys_Met_Meta_PP PF01053.20 EON33484.1 - 4.7e-140 466.5 0.0 5.3e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EON33484.1 - 8.7e-07 28.2 0.0 1.1e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EON33484.1 - 0.0001 20.9 0.0 0.0002 20.0 0.0 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EON33484.1 - 0.00018 20.9 0.0 0.00043 19.7 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EON33484.1 - 0.0003 20.1 0.0 0.00042 19.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EON33484.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Methyltransf_31 PF13847.6 EON33485.1 - 4.9e-20 71.9 0.0 6.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON33485.1 - 4.5e-14 52.9 0.1 1e-13 51.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON33485.1 - 1.3e-13 51.5 0.1 3e-13 50.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON33485.1 - 4.9e-13 49.2 0.0 8.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON33485.1 - 1.3e-10 41.8 0.1 2.3e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EON33485.1 - 2.7e-07 30.3 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EON33485.1 - 1.9e-06 27.4 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EON33485.1 - 2.6e-05 23.8 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EON33485.1 - 5.6e-05 23.0 0.0 8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EON33485.1 - 8.4e-05 23.5 1.3 0.00016 22.6 0.3 2.0 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EON33485.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EON33485.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 EON33485.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON33485.1 - 0.00083 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.15 EON33485.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 EON33485.1 - 0.0089 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EON33485.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF938 PF06080.12 EON33485.1 - 0.037 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) UPF0020 PF01170.18 EON33485.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 YdaS_antitoxin PF15943.5 EON33485.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 EON33485.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cupin_1 PF00190.22 EON33485.1 - 0.22 11.1 0.3 0.55 9.8 0.1 1.7 2 0 0 2 2 2 0 Cupin PIG-L PF02585.17 EON33486.1 - 1e-29 103.8 0.1 1.5e-29 103.2 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ribosomal_S5_C PF03719.15 EON33486.1 - 0.092 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain BTAD PF03704.17 EON33487.1 - 2.6e-19 70.1 8.5 2.6e-19 70.1 8.5 4.7 4 1 1 5 5 3 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 EON33487.1 - 0.00011 22.2 0.0 0.00044 20.3 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal AAA_25 PF13481.6 EON33487.1 - 0.00017 21.3 2.6 0.00029 20.5 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON33487.1 - 0.00094 19.6 0.2 0.00094 19.6 0.2 4.6 3 2 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EON33487.1 - 0.00094 19.5 0.0 0.0048 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 EON33487.1 - 0.019 14.9 2.9 50 4.3 0.1 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 EON33487.1 - 0.026 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 EON33487.1 - 0.047 13.1 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EON33487.1 - 0.08 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_1 PF00515.28 EON33487.1 - 0.13 12.1 1.5 20 5.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_14 PF13173.6 EON33487.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EON33487.1 - 0.24 11.5 0.4 0.61 10.1 0.4 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Na_H_antiporter PF03553.14 EON33487.1 - 0.24 10.6 0.3 0.4 9.9 0.3 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter family ArsA_ATPase PF02374.15 EON33487.1 - 0.26 10.4 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_12 PF13424.6 EON33487.1 - 2.1 8.7 24.8 0.54 10.6 0.6 5.6 5 1 0 6 6 4 0 Tetratricopeptide repeat PALP PF00291.25 EON33488.1 - 3.2e-82 276.2 13.4 5.1e-82 275.6 13.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_6 PF13740.6 EON33488.1 - 0.00075 19.4 1.4 0.00088 19.2 0.2 1.8 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 EON33488.1 - 0.0016 18.2 1.2 0.0055 16.5 0.2 2.4 2 0 0 2 2 2 1 ACT domain BTAD PF03704.17 EON33489.1 - 2.7e-24 86.2 1.9 2.7e-24 86.2 1.9 2.6 2 0 0 2 2 1 1 Bacterial transcriptional activator domain AAA_22 PF13401.6 EON33489.1 - 5e-09 36.5 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EON33489.1 - 7.2e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Trans_reg_C PF00486.28 EON33489.1 - 1.9e-07 31.1 0.0 5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_19 PF14559.6 EON33489.1 - 7.7e-07 29.5 3.6 0.049 14.1 0.2 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 EON33489.1 - 1.6e-06 28.6 1.5 6.6e-06 26.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EON33489.1 - 0.00027 20.7 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EON33489.1 - 0.0033 17.8 0.0 0.0071 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON33489.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_2 PF07719.17 EON33489.1 - 0.075 13.2 1.5 19 5.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EON33489.1 - 0.13 12.5 0.0 10 6.6 0.0 2.9 2 0 0 2 2 2 0 PPR repeat ArsA_ATPase PF02374.15 EON33489.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DnaB_C PF03796.15 EON33489.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 EON33489.1 - 0.3 11.0 0.0 0.58 10.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EON33489.1 - 0.34 10.5 4.8 0.73 9.4 1.2 2.9 2 1 0 2 2 2 0 AAA domain TPR_16 PF13432.6 EON33489.1 - 0.75 10.5 22.9 0.36 11.5 2.9 5.1 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EON33489.1 - 1.7 9.5 30.9 1 10.2 3.0 7.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 EON33490.1 - 2.4e-30 105.6 16.1 2.4e-30 105.6 16.1 1.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON33490.1 - 2.6e-10 40.0 19.6 5e-10 39.0 19.6 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein 12TM_1 PF09847.9 EON33490.1 - 0.00023 20.4 7.5 0.00026 20.2 7.5 1.1 1 0 0 1 1 1 1 Membrane protein of 12 TMs ABC_tran PF00005.27 EON33491.1 - 3.7e-26 92.3 0.0 6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON33491.1 - 1.7e-13 51.1 0.9 2.1e-10 40.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EON33491.1 - 4e-07 30.7 0.0 6.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 EON33491.1 - 0.00077 19.9 0.4 0.0017 18.8 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EON33491.1 - 0.0091 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EON33491.1 - 0.011 16.0 0.0 0.051 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON33491.1 - 0.026 14.3 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EON33491.1 - 0.036 14.6 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON33491.1 - 0.066 13.5 0.0 0.28 11.4 0.0 2.2 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EON33491.1 - 0.066 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EON33491.1 - 0.13 12.7 0.1 0.51 10.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EON33491.1 - 0.14 12.3 0.3 0.41 10.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EON33491.1 - 0.19 11.4 0.0 12 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Polyketide_cyc2 PF10604.9 EON33492.1 - 8.4e-05 22.9 0.7 0.00011 22.5 0.7 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AbiEi_4 PF13338.6 EON33493.1 - 0.0099 16.0 1.8 0.017 15.3 0.3 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin XPG_I_2 PF12813.7 EON33493.1 - 0.08 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 XPG domain containing AbiEi_3_N PF17194.4 EON33493.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain TPR_2 PF07719.17 EON33493.1 - 0.19 11.9 0.3 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Lipoprotein_Ltp PF07553.11 EON33494.1 - 7.3e-13 48.6 2.8 9.9e-12 44.9 0.4 2.3 2 0 0 2 2 2 2 Host cell surface-exposed lipoprotein GreA_GreB_N PF03449.15 EON33495.1 - 4e-24 84.6 3.5 5.5e-24 84.1 3.5 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 EON33495.1 - 8e-15 54.5 0.1 1.3e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF3299 PF11736.8 EON33495.1 - 0.071 13.1 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Vut_1 PF02592.15 EON33496.1 - 5.9e-43 146.8 5.7 5.9e-43 146.8 5.7 1.4 2 0 0 2 2 2 1 Putative vitamin uptake transporter Reo_sigma1 PF01664.16 EON33496.1 - 0.16 11.2 0.9 1.7 7.9 0.1 2.1 2 0 0 2 2 2 0 Reovirus viral attachment protein sigma 1 DUF1270 PF06900.11 EON33496.1 - 0.73 10.3 4.3 0.7 10.3 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DUF4307 PF14155.6 EON33497.1 - 2.7e-34 117.3 0.8 3.3e-34 117.0 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) RskA PF10099.9 EON33497.1 - 0.0048 17.2 1.1 0.0062 16.8 1.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF3040 PF11239.8 EON33497.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CrgA PF06781.12 EON33497.1 - 0.039 14.0 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Cell division protein CrgA DUF2371 PF10177.9 EON33497.1 - 0.041 14.1 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF3185 PF11381.8 EON33497.1 - 0.047 13.7 0.3 0.083 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) PIG-L PF02585.17 EON33498.1 - 7.6e-29 101.0 0.0 1.1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_trans_4_4 PF13579.6 EON33498.1 - 0.00022 21.7 0.6 0.14 12.6 0.2 2.4 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain SIT PF15330.6 EON33499.1 - 0.066 13.7 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4330 PF14221.6 EON33499.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) TspO_MBR PF03073.15 EON33500.1 - 1.7e-33 115.5 5.9 2e-33 115.3 5.9 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1515 PF07439.11 EON33500.1 - 0.0023 18.0 0.2 0.0048 16.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) Aminotran_3 PF00202.21 EON33501.1 - 8.2e-111 370.5 0.0 9.8e-111 370.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EON33501.1 - 0.0038 16.5 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_AsnC-type PF13404.6 EON33502.1 - 2.1e-14 53.0 1.0 2.1e-14 53.0 1.0 2.4 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 EON33502.1 - 4.5e-14 52.2 0.0 7.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EON33502.1 - 7.8e-14 51.0 0.0 1.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON33502.1 - 0.00028 20.7 1.0 0.00094 19.0 0.1 2.3 3 0 0 3 3 3 1 MarR family MarR PF01047.22 EON33502.1 - 0.0011 18.8 0.0 0.014 15.3 0.0 2.6 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EON33502.1 - 0.011 15.6 0.2 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EON33502.1 - 0.018 14.8 0.2 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain LPD37 PF18853.1 EON33502.1 - 0.032 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 37 Sigma70_r4 PF04545.16 EON33502.1 - 0.073 12.6 1.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DAHP_synth_1 PF00793.20 EON33503.1 - 5.6e-98 327.2 0.0 6.6e-98 326.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PhoD PF09423.10 EON33504.1 - 6.9e-100 334.5 1.4 8.2e-100 334.2 1.4 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EON33504.1 - 1e-31 109.3 0.0 2.1e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain PepSY_TM PF03929.16 EON33505.1 - 2.8e-63 214.3 9.9 3.8e-63 213.8 9.9 1.2 1 0 0 1 1 1 1 PepSY-associated TM region DUF4131 PF13567.6 EON33505.1 - 0.0014 18.3 0.5 0.0014 18.3 0.5 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4131) DUF4079 PF13301.6 EON33505.1 - 1.2 9.3 9.8 6.8 6.8 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) DUF5325 PF17259.2 EON33506.1 - 5.7 6.9 7.9 1.5 8.7 2.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5325) HlyIII PF03006.20 EON33507.1 - 2e-36 125.8 11.0 2.4e-36 125.5 11.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related Prenyltransf PF01255.19 EON33508.1 - 1.3e-73 247.2 0.0 1.6e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Aminotran_1_2 PF00155.21 EON33509.1 - 6.3e-19 68.4 0.0 9.8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EON33509.1 - 6.3e-13 48.2 0.3 1.7e-12 46.8 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EON33509.1 - 0.018 14.6 0.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF4051 PF13260.6 EON33509.1 - 0.034 13.9 1.1 0.086 12.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) HTH_Crp_2 PF13545.6 EON33509.1 - 0.045 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 EON33509.1 - 0.22 11.5 0.0 0.53 10.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NAD_binding_10 PF13460.6 EON33510.1 - 2.1e-05 24.5 11.5 0.0006 19.7 11.5 2.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON33510.1 - 0.0027 17.2 0.9 0.0043 16.5 0.9 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ArsB PF02040.15 EON33510.1 - 0.0041 16.5 0.6 0.0057 16.0 0.6 1.2 1 0 0 1 1 1 1 Arsenical pump membrane protein RmlD_sub_bind PF04321.17 EON33510.1 - 0.0046 16.1 1.7 0.0081 15.3 0.6 1.9 2 1 1 3 3 3 1 RmlD substrate binding domain NmrA PF05368.13 EON33510.1 - 0.032 13.8 5.0 1.3 8.5 3.5 2.4 2 1 0 2 2 2 0 NmrA-like family DapB_N PF01113.20 EON33510.1 - 0.038 14.1 1.5 0.082 13.0 1.5 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CMD PF02627.20 EON33511.1 - 7.3e-15 54.8 1.3 7.3e-15 54.8 1.3 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CRS1_YhbY PF01985.21 EON33511.1 - 0.21 11.8 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain PRK PF00485.18 EON33512.1 - 5.1e-14 52.5 0.0 8.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 EON33512.1 - 0.04 13.6 0.1 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_18 PF13238.6 EON33512.1 - 0.042 14.4 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2268 PF10026.9 EON33513.1 - 0.011 15.4 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) DUF885 PF05960.11 EON33513.1 - 0.016 14.9 0.9 0.016 14.9 0.9 1.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF885) SHMT PF00464.19 EON33514.1 - 9.9e-159 528.2 0.0 1.2e-158 528.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EON33514.1 - 8.8e-05 21.9 0.0 0.00046 19.6 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DUF4157 PF13699.6 EON33514.1 - 0.0052 17.0 0.5 0.17 12.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4157) SelA PF03841.13 EON33514.1 - 0.0057 15.7 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Cys_Met_Meta_PP PF01053.20 EON33514.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EON33514.1 - 0.052 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EON33514.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V FA_desaturase_2 PF03405.14 EON33515.1 - 1.2e-24 86.8 0.0 1.6e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PhoH PF02562.16 EON33516.1 - 1.5e-52 178.1 0.0 1.9e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 EON33516.1 - 6.6e-29 100.8 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 EON33516.1 - 1.5e-07 31.3 0.1 2.9e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain MoCF_biosynth PF00994.24 EON33516.1 - 0.0083 15.8 0.1 0.046 13.4 0.1 2.2 2 0 0 2 2 2 1 Probable molybdopterin binding domain AAA_16 PF13191.6 EON33516.1 - 0.012 16.0 0.7 0.033 14.6 0.7 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EON33516.1 - 0.024 14.9 1.0 0.18 12.1 1.0 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EON33516.1 - 0.03 14.1 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase YkuD PF03734.14 EON33517.1 - 8.6e-06 26.2 0.5 1.7e-05 25.3 0.3 1.5 1 1 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF2076 PF09849.9 EON33517.1 - 7.1 6.6 5.7 2 8.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Usp PF00582.26 EON33518.1 - 1e-40 139.5 12.6 2.3e-25 89.7 2.6 2.1 2 0 0 2 2 2 2 Universal stress protein family RraA-like PF03737.15 EON33518.1 - 0.083 13.1 0.1 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Aldolase/RraA Response_reg PF00072.24 EON33519.1 - 1e-22 80.4 0.1 1.3e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GAF_2 PF13185.6 EON33520.1 - 3.4e-23 82.5 3.5 4.9e-13 49.6 0.1 2.6 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 EON33520.1 - 6.3e-19 68.9 0.7 5e-10 40.1 0.0 2.8 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 EON33520.1 - 3.2e-15 56.6 0.2 9.3e-07 29.2 0.1 3.5 2 2 0 2 2 2 2 GAF domain HisKA_3 PF07730.13 EON33520.1 - 2.1e-09 37.8 3.0 2.1e-09 37.8 3.0 3.2 3 1 1 4 4 4 1 Histidine kinase HATPase_c PF02518.26 EON33520.1 - 1.8e-06 28.4 0.0 1.2e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EON33520.1 - 2.1e-05 24.5 0.0 7.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain FlxA PF14282.6 EON33520.1 - 0.47 10.5 1.9 1.4 9.0 1.9 1.7 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 EON33520.1 - 4.6 7.1 5.6 8.4 6.3 0.4 2.9 3 0 0 3 3 3 0 Septum formation initiator ACR_tran PF00873.19 EON33521.1 - 0.013 13.2 1.9 0.015 13.0 1.9 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Polysacc_synt_3 PF13440.6 EON33521.1 - 0.029 13.6 0.9 0.033 13.4 0.9 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4133 PF13571.6 EON33521.1 - 0.035 14.4 1.3 0.044 14.1 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) DUF4191 PF13829.6 EON33521.1 - 0.04 13.2 2.3 0.052 12.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4407 PF14362.6 EON33521.1 - 5.1 6.4 6.1 6.2 6.1 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIG-L PF02585.17 EON33522.1 - 2.6e-22 79.8 0.0 4.2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF4350 PF14258.6 EON33522.1 - 0.085 13.3 0.9 5.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Lyase_1 PF00206.20 EON33523.1 - 1.3e-102 343.4 0.0 1.9e-102 342.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EON33523.1 - 2.5e-21 75.8 0.6 2.2e-20 72.8 0.5 2.4 2 0 0 2 2 2 1 Fumarase C C-terminus Fumerase_C PF05683.12 EON33524.1 - 1.2e-86 289.3 0.0 1.8e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 EON33524.1 - 1e-85 287.5 0.0 1.3e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Histone_H2A_C PF16211.5 EON33524.1 - 0.032 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 C-terminus of histone H2A FBPase_glpX PF03320.13 EON33525.1 - 1.8e-141 470.4 6.5 2.1e-141 470.3 6.5 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF4245 PF14030.6 EON33526.1 - 3.1e-41 141.2 0.0 3.6e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) Exonuc_VII_S PF02609.16 EON33528.1 - 3e-17 62.4 0.1 3.6e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit Exonuc_VII_L PF02601.15 EON33529.1 - 2.5e-64 217.7 0.1 8.2e-56 189.8 0.3 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 EON33529.1 - 9.6e-17 61.0 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 EON33529.1 - 7.4e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peptidase_S66 PF02016.15 EON33529.1 - 0.063 13.4 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain MSA-2c PF12238.8 EON33530.1 - 4.9 7.1 6.1 7.7 6.5 6.1 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c LYTB PF02401.18 EON33531.1 - 2.4e-88 295.8 0.0 2.8e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 LytB protein GAD PF02938.14 EON33531.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 GAD domain DUF1445 PF07286.12 EON33531.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) Peptidase_S8 PF00082.22 EON33532.1 - 1.5e-32 113.1 0.8 3.9e-32 111.7 0.8 1.7 1 1 0 1 1 1 1 Subtilase family YukD PF08817.10 EON33533.1 - 1.9e-21 76.6 2.1 4.9e-21 75.2 0.6 2.2 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD TRAP_beta PF05753.14 EON33533.1 - 0.24 10.8 0.5 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) 7TMR-DISM_7TM PF07695.11 EON33533.1 - 1.4 8.7 23.1 0.28 11.1 4.5 2.7 3 0 0 3 3 3 0 7TM diverse intracellular signalling FtsK_SpoIIIE PF01580.18 EON33534.1 - 2.2e-105 351.4 0.1 1.8e-60 204.4 0.0 5.2 4 1 1 5 5 5 4 FtsK/SpoIIIE family NACHT PF05729.12 EON33534.1 - 3.8e-08 33.4 0.0 1.7 8.5 0.0 4.7 4 1 0 4 4 4 3 NACHT domain AAA_22 PF13401.6 EON33534.1 - 5e-07 30.1 0.0 0.042 14.1 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 EON33534.1 - 0.00024 21.4 2.6 0.13 12.6 0.1 3.8 3 2 0 3 3 3 1 AAA domain DUF87 PF01935.17 EON33534.1 - 0.0023 18.1 0.1 0.39 10.8 0.1 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_16 PF13191.6 EON33534.1 - 0.003 18.0 2.0 2.7 8.3 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EON33534.1 - 0.0072 16.4 0.1 0.46 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EON33534.1 - 0.011 15.5 0.6 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EON33534.1 - 0.014 15.8 0.0 35 4.8 0.0 3.4 3 0 0 3 3 3 0 RNA helicase Adeno_IVa2 PF02456.15 EON33534.1 - 0.028 13.2 0.1 4.3 6.0 0.1 2.6 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_10 PF12846.7 EON33534.1 - 0.063 12.2 0.1 3.9 6.3 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain GTP_EFTU PF00009.27 EON33534.1 - 0.072 12.6 0.0 6 6.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EON33534.1 - 0.14 11.9 0.0 22 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EON33534.1 - 0.14 12.6 0.0 24 5.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.9 EON33534.1 - 0.2 10.6 0.5 1.2 7.9 0.1 2.4 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Ribosomal_L13 PF00572.18 EON33536.1 - 6e-54 181.6 0.1 7.5e-54 181.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 EON33537.1 - 3.7e-44 150.1 0.1 5.3e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PGM_PMM_I PF02878.16 EON33538.1 - 1.1e-41 141.7 0.0 3.1e-41 140.3 0.0 1.7 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EON33538.1 - 3e-28 98.3 0.7 6.9e-28 97.1 0.7 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EON33538.1 - 1.4e-20 73.9 0.5 3e-20 72.8 0.5 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EON33538.1 - 8.1e-14 51.6 1.4 2.4e-13 50.1 1.4 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HAD_2 PF13419.6 EON33539.1 - 1.5e-11 44.7 0.0 4.9e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON33539.1 - 1.7e-08 35.1 0.1 7.3e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON33539.1 - 4.6e-06 26.6 0.1 1.2e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like T7SS_ESX_EspC PF10824.8 EON33540.1 - 0.039 14.4 6.8 0.052 14.0 6.5 1.4 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm DUF2407 PF10302.9 EON33542.1 - 0.071 13.7 0.1 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Chlorophyllase2 PF12740.7 EON33543.1 - 5.2e-07 28.8 0.0 7.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 EON33543.1 - 5.2e-06 25.2 0.5 0.00037 19.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 EON33543.1 - 0.00011 21.4 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.25 EON33543.1 - 0.013 15.3 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Lipase (class 3) SIS PF01380.22 EON33544.1 - 1.8e-54 183.1 0.1 1.1e-32 112.6 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EON33544.1 - 4.6e-22 78.6 0.9 1.5e-21 77.0 0.4 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EON33544.1 - 1.9e-17 63.3 0.0 3.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 EON33544.1 - 0.0055 16.7 1.0 0.021 14.8 0.0 2.6 3 0 0 3 3 3 1 SIS domain GATase_4 PF13230.6 EON33544.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Carb_kinase PF01256.17 EON33545.1 - 1.2e-52 178.9 6.8 1.2e-52 178.9 6.8 1.7 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 EON33545.1 - 4.9e-37 127.4 1.7 9.8e-37 126.5 1.7 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus HK PF02110.15 EON33545.1 - 0.037 13.4 0.9 0.24 10.8 0.8 2.0 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family DUF2721 PF11026.8 EON33546.1 - 4.8 7.1 11.2 0.67 9.8 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Ala_racemase_N PF01168.20 EON33547.1 - 1.5e-58 198.0 4.3 1.9e-58 197.7 4.3 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 EON33547.1 - 3.8e-41 139.8 0.4 8.1e-41 138.7 0.4 1.6 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain UPRTase PF14681.6 EON33547.1 - 0.13 11.7 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Hydrolase_4 PF12146.8 EON33548.1 - 1.2e-23 83.6 0.5 1.8e-22 79.8 0.5 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON33548.1 - 2.6e-23 83.0 0.0 7.7e-16 58.5 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON33548.1 - 2.7e-23 83.7 9.7 4.3e-23 83.1 9.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON33548.1 - 2.7e-08 34.2 0.0 7e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EON33548.1 - 0.0001 22.2 0.1 0.14 12.0 0.0 2.5 1 1 0 2 2 2 2 Serine hydrolase Abhydrolase_4 PF08386.10 EON33548.1 - 0.00013 22.0 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 EON33548.1 - 0.00014 21.4 0.8 0.59 9.6 0.6 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EON33548.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 EON33548.1 - 0.0057 16.5 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 EON33548.1 - 0.016 15.0 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 EON33548.1 - 0.12 12.0 0.0 1.8 8.2 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 EON33548.1 - 0.22 11.2 0.4 0.41 10.3 0.4 1.4 1 0 0 1 1 1 0 PGAP1-like protein TsaE PF02367.17 EON33549.1 - 4.6e-29 101.0 0.0 5.4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EON33549.1 - 0.017 15.3 0.1 0.032 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EON33549.1 - 0.034 13.9 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EON33549.1 - 0.079 12.1 0.7 0.11 11.7 0.7 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 EON33549.1 - 0.21 11.5 0.4 0.4 10.6 0.4 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 EON33549.1 - 0.22 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 EON33549.1 - 0.23 11.0 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EON33549.1 - 0.4 11.1 0.1 0.4 11.1 0.1 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Peptidase_M22 PF00814.25 EON33550.1 - 8.8e-27 94.5 1.8 4.2e-26 92.2 0.4 2.0 2 0 0 2 2 2 1 Glycoprotease family Acetyltransf_1 PF00583.25 EON33551.1 - 1.2e-18 67.4 0.0 1.5e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON33551.1 - 4.3e-13 49.5 0.0 5.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON33551.1 - 3.2e-11 43.3 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON33551.1 - 3.1e-07 30.3 0.0 4.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EON33551.1 - 1.9e-06 28.6 0.0 2.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EON33551.1 - 1.5e-05 24.7 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON33551.1 - 0.00012 22.2 0.0 0.00084 19.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EON33551.1 - 0.00037 20.6 0.0 0.00048 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON33551.1 - 0.00046 20.3 0.0 0.00091 19.3 0.0 1.6 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EON33551.1 - 0.15 11.5 0.0 0.39 10.1 0.0 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Peptidase_M22 PF00814.25 EON33552.1 - 5.9e-87 291.8 0.2 6.8e-87 291.6 0.2 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EON33552.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Cpn10 PF00166.21 EON33553.1 - 2.9e-36 123.4 1.4 3.2e-36 123.3 1.4 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Peptidase_M23 PF01551.22 EON33553.1 - 0.054 13.7 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M23 Cupin_2 PF07883.11 EON33553.1 - 0.093 12.5 0.4 0.13 12.0 0.4 1.4 1 1 0 1 1 1 0 Cupin domain Cpn60_TCP1 PF00118.24 EON33554.1 - 8.2e-88 295.2 12.6 2.9e-87 293.4 12.6 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_CodY PF08222.11 EON33554.1 - 0.18 11.4 0.2 0.18 11.4 0.2 2.5 3 0 0 3 3 3 0 CodY helix-turn-helix domain Whib PF02467.16 EON33555.1 - 9.1e-24 83.8 1.3 1.1e-23 83.6 1.3 1.1 1 0 0 1 1 1 1 Transcription factor WhiB Sigma70_r4_2 PF08281.12 EON33557.1 - 7.8e-12 44.7 1.1 2e-11 43.3 1.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33557.1 - 6.5e-11 41.6 0.3 1.2e-10 40.7 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EON33557.1 - 6.2e-10 38.7 0.3 1.3e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 EON33557.1 - 0.00025 21.0 0.5 0.0022 17.9 0.5 1.9 1 1 0 1 1 1 1 ECF sigma factor HTH_16 PF12645.7 EON33557.1 - 0.0004 20.4 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 EON33557.1 - 0.033 13.7 0.1 0.087 12.4 0.1 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family RsdA_SigD_bd PF16751.5 EON33558.1 - 2.5e-15 56.4 2.0 4.2e-15 55.7 0.1 2.3 2 0 0 2 2 2 1 Anti-sigma-D factor RsdA to sigma factor binding region DUF5319 PF17252.2 EON33559.1 - 3.2e-51 172.6 0.5 3.9e-51 172.4 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5319) IMPDH PF00478.25 EON33560.1 - 8.1e-156 518.3 8.8 9.3e-156 518.1 8.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EON33560.1 - 7.9e-22 77.5 0.3 6.7e-10 39.3 0.1 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EON33560.1 - 2.5e-09 37.0 14.6 4.4e-06 26.3 10.2 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EON33560.1 - 1.9e-08 33.7 8.3 2.2e-07 30.3 8.7 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EON33560.1 - 1.5e-05 24.6 5.3 0.046 13.2 0.8 2.3 1 1 0 2 2 2 2 Histidine biosynthesis protein PRC PF05239.16 EON33560.1 - 0.0038 17.3 0.5 0.76 9.9 0.0 3.3 3 1 0 3 3 3 1 PRC-barrel domain G3P_antiterm PF04309.12 EON33560.1 - 0.16 11.4 1.6 6.8 6.1 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PGA_cap PF09587.10 EON33560.1 - 0.19 11.2 1.4 12 5.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Glu_synthase PF01645.17 EON33560.1 - 0.21 10.7 11.2 0.039 13.1 7.5 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EON33560.1 - 0.38 9.9 6.3 0.45 9.7 1.4 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Dus PF01207.17 EON33560.1 - 0.44 9.6 2.5 7.2 5.6 0.1 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF561 PF04481.12 EON33560.1 - 1.4 8.0 3.4 5.6 6.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) PcrB PF01884.17 EON33560.1 - 1.9 7.9 11.1 1.1 8.7 1.3 4.1 2 1 3 5 5 5 0 PcrB family IMPDH PF00478.25 EON33561.1 - 4.3e-31 108.2 2.9 6.9e-31 107.5 1.8 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EON33561.1 - 2.1e-07 30.3 5.6 4.1e-07 29.3 5.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EON33561.1 - 9.7e-05 21.7 4.9 0.00015 21.1 4.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 EON33561.1 - 0.0019 17.3 2.1 0.01 14.9 0.3 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EON33561.1 - 0.054 12.9 2.2 0.89 9.0 0.2 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 EON33561.1 - 0.06 12.7 13.2 0.2 11.0 2.7 2.4 1 1 1 2 2 2 0 Nitronate monooxygenase NanE PF04131.14 EON33561.1 - 0.11 11.7 4.2 3.6 6.7 0.1 3.1 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 EON33561.1 - 0.17 11.2 7.7 0.37 10.1 1.3 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EON33561.1 - 0.68 9.1 4.5 0.83 8.8 0.7 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase LRV PF01816.17 EON33561.1 - 9.6 6.9 7.1 0.68 10.5 0.5 2.8 3 0 0 3 3 3 0 Leucine rich repeat variant GMC_oxred_N PF00732.19 EON33562.1 - 1.1e-12 48.0 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EON33562.1 - 1.4e-11 45.1 0.1 2.9e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EON33562.1 - 1e-10 41.7 1.7 6.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON33562.1 - 5.3e-09 35.6 0.4 0.00024 20.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EON33562.1 - 3e-05 23.4 0.0 0.00077 18.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON33562.1 - 0.00091 19.4 1.1 0.0025 18.0 0.6 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON33562.1 - 0.0014 19.1 0.2 0.15 12.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON33562.1 - 0.003 16.8 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Fer4_9 PF13187.6 EON33562.1 - 0.013 15.6 0.2 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EON33562.1 - 0.02 15.3 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 EON33562.1 - 0.032 14.0 3.9 0.058 13.2 3.9 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_10 PF13237.6 EON33562.1 - 0.044 13.9 0.4 0.076 13.1 0.4 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EON33562.1 - 0.065 13.8 1.2 0.13 12.8 1.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 EON33562.1 - 0.19 10.8 0.0 8.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Fer4_6 PF12837.7 EON33562.1 - 0.29 11.3 3.9 0.52 10.5 3.9 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 EON33562.1 - 0.64 11.1 6.4 1.1 10.4 6.4 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_2 PF12797.7 EON33562.1 - 0.98 9.7 4.7 1.8 8.8 4.7 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_4 PF12800.7 EON33562.1 - 1.4 9.6 3.6 2.4 8.9 3.6 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain CbiQ PF02361.16 EON33563.1 - 9e-11 41.8 16.2 9.2e-10 38.5 16.2 2.2 1 1 0 1 1 1 1 Cobalt transport protein ABC_tran PF00005.27 EON33564.1 - 1.2e-27 97.0 0.0 1.6e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON33564.1 - 1.2e-10 41.2 0.3 1e-09 38.2 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON33564.1 - 3.5e-09 36.9 4.4 5.6e-05 23.1 0.4 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON33564.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON33564.1 - 0.0028 18.1 0.3 0.0049 17.3 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EON33564.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_15 PF13175.6 EON33564.1 - 0.0049 16.6 0.0 0.016 15.0 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EON33564.1 - 0.0065 17.0 0.0 0.0081 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 EON33564.1 - 0.0073 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 EON33564.1 - 0.012 15.9 0.3 0.051 13.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON33564.1 - 0.023 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EON33564.1 - 0.035 14.2 0.3 0.054 13.6 0.3 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 EON33564.1 - 0.06 12.0 0.0 0.082 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EON33564.1 - 0.066 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON33564.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EON33564.1 - 0.079 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Poly_export PF02563.16 EON33564.1 - 0.095 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein NB-ARC PF00931.22 EON33564.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EON33564.1 - 0.14 12.3 0.4 0.22 11.6 0.4 1.9 1 1 0 1 1 1 0 AAA domain GMP_synt_C PF00958.22 EON33566.1 - 2.8e-38 129.9 0.0 5.6e-38 128.9 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EON33566.1 - 7.8e-38 130.1 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EON33566.1 - 5.8e-09 35.4 0.2 2.5e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EON33566.1 - 2.5e-08 34.0 0.0 7.8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.21 EON33566.1 - 0.0015 18.3 0.3 0.0039 16.9 0.3 1.6 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.16 EON33566.1 - 0.0021 16.9 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 EON33566.1 - 0.014 14.9 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 EON33566.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 EON33566.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Ycf66_N PF07444.11 EON33567.1 - 0.16 12.1 1.3 0.27 11.4 1.2 1.6 1 1 0 1 1 1 0 Ycf66 protein N-terminus PspC PF04024.12 EON33568.1 - 1.6e-14 53.4 0.7 4e-14 52.2 0.7 1.7 1 0 0 1 1 1 1 PspC domain DUF2154 PF09922.9 EON33568.1 - 6.7e-08 32.4 0.0 1.7e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Cell wall-active antibiotics response 4TMS YvqF Acyl_transf_3 PF01757.22 EON33568.1 - 0.016 14.3 5.2 0.024 13.7 0.2 2.2 2 0 0 2 2 2 0 Acyltransferase family TetR_C_14 PF17754.1 EON33568.1 - 1.2 9.1 4.0 1.1 9.2 0.3 2.5 2 0 0 2 2 2 0 MftR C-terminal domain PspC PF04024.12 EON33569.1 - 1.4e-12 47.3 2.5 1.4e-12 47.3 2.5 2.2 2 0 0 2 2 2 1 PspC domain HATPase_c PF02518.26 EON33569.1 - 8.2e-07 29.5 0.2 2.1e-06 28.2 0.2 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EON33569.1 - 1.3e-05 25.2 0.1 3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA_3 PF07730.13 EON33569.1 - 0.0014 19.1 2.0 0.0051 17.3 2.0 2.1 1 1 0 1 1 1 1 Histidine kinase DUF1772 PF08592.11 EON33569.1 - 6.3 7.1 8.4 3.2 8.1 0.5 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) GerE PF00196.19 EON33570.1 - 1.5e-18 66.1 0.7 2.1e-18 65.6 0.2 1.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 EON33570.1 - 3.2e-14 53.0 0.0 4.3e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Sigma70_r4_2 PF08281.12 EON33570.1 - 4.4e-06 26.3 0.2 8.2e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EON33570.1 - 7.3e-06 25.6 0.1 1.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Trp_repressor PF01371.19 EON33570.1 - 3.7e-05 23.8 0.2 5.8e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Trp repressor protein Sigma70_r4 PF04545.16 EON33570.1 - 0.00024 20.6 1.3 0.00041 19.8 1.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 EON33570.1 - 0.0007 19.7 0.1 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EON33570.1 - 0.0054 16.3 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 EON33570.1 - 0.03 14.1 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2285 PF10074.9 EON33570.1 - 0.035 14.7 0.1 0.073 13.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) TadZ_N PF16968.5 EON33570.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal HTH_40 PF14493.6 EON33570.1 - 0.064 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 EON33570.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Sigma70_ECF PF07638.11 EON33570.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 ECF sigma factor HTH_10 PF04967.12 EON33570.1 - 0.14 12.0 0.4 0.99 9.3 0.4 2.2 1 1 0 1 1 1 0 HTH DNA binding domain Pkinase PF00069.25 EON33571.1 - 1.7e-47 162.0 0.0 2.2e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON33571.1 - 2.7e-34 118.6 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON33571.1 - 3.4e-06 27.2 1.6 2.9e-05 24.1 1.5 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EON33571.1 - 0.00023 20.6 0.0 0.047 13.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EON33571.1 - 0.0006 18.7 0.0 0.00079 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EON33571.1 - 0.0012 18.2 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EON33571.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Radical_SAM PF04055.21 EON33572.1 - 1.6e-12 48.1 0.0 2.9e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EON33572.1 - 0.0049 17.2 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain PEP_hydrolase PF09370.10 EON33572.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like IMS PF00817.20 EON33574.1 - 1.7e-11 44.4 0.2 3.3e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family DUF1805 PF08827.11 EON33574.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Ala_racemase_N PF01168.20 EON33576.1 - 6.8e-31 107.6 0.8 3.7e-30 105.2 0.5 1.9 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 EON33576.1 - 2.8e-17 63.2 2.2 3.9e-17 62.7 0.9 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain AP_endonuc_2 PF01261.24 EON33576.1 - 0.0032 16.9 0.1 1.7 8.1 0.0 2.4 1 1 0 2 2 2 2 Xylose isomerase-like TIM barrel adh_short PF00106.25 EON33577.1 - 3.7e-50 170.1 4.3 2.4e-48 164.2 2.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.12 EON33577.1 - 1.4e-43 148.9 0.0 8e-43 146.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 EON33577.1 - 1.6e-32 112.9 2.6 1.6e-32 112.9 2.6 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EON33577.1 - 1.1e-20 74.2 0.2 1.5e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EON33577.1 - 3e-17 63.1 4.7 3.6e-14 53.1 1.4 2.5 2 1 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 EON33577.1 - 7.9e-16 58.4 0.1 8.9e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EON33577.1 - 1.5e-12 47.8 8.1 1.8e-09 37.8 0.3 2.7 2 1 0 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 EON33577.1 - 2.5e-12 46.4 0.0 2.6e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EON33577.1 - 2.8e-09 36.5 0.3 9.9e-06 24.9 0.0 2.9 3 1 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EON33577.1 - 4e-09 36.0 0.1 0.0022 17.2 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EON33577.1 - 0.0001 22.5 0.2 0.003 17.8 0.2 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EON33577.1 - 0.00098 18.7 1.1 0.35 10.4 0.3 2.4 2 0 0 2 2 2 2 NmrA-like family ADH_zinc_N PF00107.26 EON33577.1 - 0.031 14.3 0.1 0.081 12.9 0.1 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EON33577.1 - 0.051 12.9 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EON33577.1 - 0.065 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain E1-E2_ATPase PF00122.20 EON33578.1 - 5.6e-43 146.5 1.3 5.6e-43 146.5 1.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EON33578.1 - 5.8e-33 115.0 3.3 1.3e-32 113.8 3.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON33578.1 - 0.00096 19.0 0.7 0.0015 18.4 0.7 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CE2_N PF17996.1 EON33578.1 - 0.065 13.2 0.0 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal HTH_5 PF01022.20 EON33579.1 - 6.8e-16 57.9 0.1 6.8e-16 57.9 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON33579.1 - 6.7e-12 45.3 1.4 1.1e-11 44.5 1.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EON33579.1 - 1.4e-07 31.3 1.0 2.3e-07 30.6 1.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EON33579.1 - 9.6e-05 22.8 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EON33579.1 - 0.00026 20.5 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EON33579.1 - 0.00036 20.5 0.3 0.00055 19.9 0.3 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 EON33579.1 - 0.00052 19.9 0.1 0.00087 19.2 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 EON33579.1 - 0.0006 19.6 0.9 0.0016 18.2 0.9 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EON33579.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_1 PF00126.27 EON33579.1 - 0.0041 17.0 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Rrf2 PF02082.20 EON33579.1 - 0.013 15.9 0.1 0.019 15.3 0.1 1.4 1 1 0 1 1 1 0 Transcriptional regulator HTH_AsnC-type PF13404.6 EON33579.1 - 0.014 15.2 0.2 0.03 14.1 0.2 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain LexA_DNA_bind PF01726.16 EON33579.1 - 0.016 14.9 0.1 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 LexA DNA binding domain HxlR PF01638.17 EON33579.1 - 0.028 14.3 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_9 PF08221.11 EON33579.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HrcA_DNA-bdg PF03444.15 EON33579.1 - 0.078 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF746 PF05344.11 EON33579.1 - 0.09 12.6 0.2 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) DprA_WH PF17782.1 EON33579.1 - 0.092 12.9 1.9 0.15 12.2 1.9 1.4 1 0 0 1 1 1 0 DprA winged helix domain DNA_pol3_alpha PF07733.12 EON33580.1 - 7.8e-76 255.1 0.0 4.7e-57 193.5 0.0 2.5 2 1 1 3 3 3 2 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 EON33580.1 - 9.2e-59 197.5 0.0 1.9e-58 196.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 EON33580.1 - 1.5e-29 103.4 0.0 2.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 EON33580.1 - 6.2e-28 96.9 0.1 4.9e-27 94.0 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 EON33580.1 - 4.5e-05 23.4 0.0 8.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HHH_3 PF12836.7 EON33580.1 - 0.00011 22.3 0.0 0.00044 20.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_4 PF14490.6 EON33580.1 - 0.18 11.8 0.0 1.5 8.8 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix containing domain DUF167 PF02594.16 EON33581.1 - 7.8e-18 64.4 0.1 8.5e-18 64.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 SpoU_methylase PF00588.19 EON33582.1 - 1.8e-29 102.8 0.0 2e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family PALP PF00291.25 EON33583.1 - 5.1e-61 206.6 3.6 6e-61 206.4 3.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 EON33584.1 - 5e-60 201.5 0.5 6.4e-60 201.1 0.5 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EON33584.1 - 1.3e-31 109.2 0.0 1.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 EON33584.1 - 0.0047 16.2 0.8 0.0047 16.2 0.8 2.2 2 1 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain OCD_Mu_crystall PF02423.15 EON33584.1 - 0.0049 15.9 0.5 0.0073 15.3 0.5 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EON33584.1 - 0.17 11.9 1.0 3.2 7.8 0.1 2.5 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF3017 PF11222.8 EON33585.1 - 2.3e-25 88.7 13.2 2.9e-25 88.3 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3017) DUF4131 PF13567.6 EON33585.1 - 6.6 6.4 8.3 2.1 8.0 5.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HSP70 PF00012.20 EON33586.1 - 2e-07 29.6 0.0 2.8e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 EON33586.1 - 0.02 14.4 1.0 0.032 13.7 1.0 1.5 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family CoA_trans PF01144.23 EON33586.1 - 0.026 13.9 0.2 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 Coenzyme A transferase Abhydrolase_1 PF00561.20 EON33587.1 - 3.8e-30 105.4 0.1 4.4e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON33587.1 - 0.00044 19.6 0.0 0.0015 17.8 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EON33587.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Cys_Met_Meta_PP PF01053.20 EON33588.1 - 2.8e-138 460.6 0.0 3.2e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EON33588.1 - 0.00072 18.6 0.1 0.0023 16.9 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EON33588.1 - 0.0045 16.3 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Beta-eliminating lyase Sugarporin_N PF11471.8 EON33588.1 - 0.18 11.8 0.4 0.86 9.6 0.0 2.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension PE-PPE PF08237.11 EON33589.1 - 8.1e-11 41.9 0.0 3.1e-08 33.5 0.1 2.4 2 0 0 2 2 2 2 PE-PPE domain Cutinase PF01083.22 EON33589.1 - 9e-08 32.3 2.9 9.7e-07 28.9 2.9 2.2 1 1 0 1 1 1 1 Cutinase MFS_1 PF07690.16 EON33590.1 - 3e-37 128.4 65.5 2.7e-27 95.6 32.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON33590.1 - 4.9e-09 35.6 11.9 4.9e-09 35.6 11.9 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 EON33590.1 - 0.069 12.4 53.4 0.14 11.4 53.5 1.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Ferritin PF00210.24 EON33591.1 - 1.3e-35 122.5 2.6 1.4e-35 122.3 2.6 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 EON33591.1 - 0.0044 17.4 0.3 0.51 10.7 0.1 2.1 2 0 0 2 2 2 2 Rubrerythrin DUF455 PF04305.14 EON33591.1 - 0.1 12.1 0.3 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Fer2_BFD PF04324.15 EON33592.1 - 1.6e-10 41.1 4.3 1.9e-10 40.9 4.3 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Exo_endo_phos PF03372.23 EON33593.1 - 1.4e-17 64.0 1.6 1.8e-17 63.7 1.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA-synt_1b PF00579.25 EON33594.1 - 3.7e-76 256.3 0.0 4.6e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Virul_fac_BrkB PF03631.15 EON33595.1 - 1.7e-37 129.5 23.3 2.6e-37 128.9 23.3 1.2 1 0 0 1 1 1 1 Virulence factor BrkB Gemini_mov PF01708.16 EON33595.1 - 2.5 7.9 6.7 1.2 8.9 3.8 2.1 2 1 0 2 2 2 0 Geminivirus putative movement protein Peptidase_S11 PF00768.20 EON33596.1 - 9.1e-34 117.0 0.0 1.4e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EON33596.1 - 5.1e-11 42.6 0.1 1.7e-10 40.8 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EON33596.1 - 0.027 13.7 0.3 2.1 7.5 0.2 2.5 1 1 1 2 2 2 0 Beta-lactamase Peptidase_S13 PF02113.15 EON33596.1 - 0.031 13.0 0.0 0.078 11.7 0.0 1.5 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Transpeptidase PF00905.22 EON33596.1 - 0.071 12.3 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Penicillin binding protein transpeptidase domain GATase PF00117.28 EON33597.1 - 1.6e-17 63.9 0.0 2.4e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EON33597.1 - 1.5e-08 34.7 0.1 6.9e-08 32.5 0.0 2.0 3 0 0 3 3 3 1 Peptidase C26 DJ-1_PfpI PF01965.24 EON33597.1 - 0.0023 17.7 0.0 0.0079 16.0 0.0 1.8 1 1 0 2 2 2 1 DJ-1/PfpI family GATase_3 PF07685.14 EON33597.1 - 0.039 13.6 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MG2 PF01835.19 EON33598.1 - 0.12 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 MG2 domain p450 PF00067.22 EON33599.1 - 8.9e-21 74.2 0.0 3.4e-15 55.8 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 TetR_N PF00440.23 EON33600.1 - 9e-09 35.0 0.4 1.6e-08 34.2 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Fer2_3 PF13085.6 EON33601.1 - 4.7e-32 110.2 0.0 8.8e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 EON33601.1 - 1.9e-10 41.0 1.9 3.7e-10 40.1 1.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EON33601.1 - 6.9e-10 38.9 3.4 1.2e-09 38.1 3.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EON33601.1 - 8.8e-06 26.2 1.4 1.7e-05 25.3 1.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EON33601.1 - 0.00086 19.4 6.4 0.00086 19.4 6.4 2.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EON33601.1 - 0.012 16.2 12.1 0.027 15.1 9.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EON33601.1 - 0.015 16.2 4.4 0.71 10.8 0.6 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 EON33601.1 - 0.022 15.2 10.5 0.64 10.7 4.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 EON33601.1 - 0.023 14.5 10.0 0.21 11.4 5.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EON33601.1 - 0.026 14.7 2.2 0.3 11.3 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EON33601.1 - 0.13 13.0 5.4 1.5 9.6 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_6 PF12837.7 EON33601.1 - 0.18 11.9 7.9 1.3 9.2 2.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 EON33601.1 - 0.34 11.1 16.8 0.47 10.6 7.3 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 EON33601.1 - 1.6 8.6 9.4 3 7.7 0.2 2.5 1 1 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_3 PF12798.7 EON33601.1 - 9.2 7.5 15.8 8 7.7 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FAD_binding_2 PF00890.24 EON33602.1 - 1.7e-112 376.6 3.2 2.3e-112 376.1 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EON33602.1 - 1.3e-42 144.9 0.8 2.1e-42 144.1 0.8 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EON33602.1 - 2.9e-05 23.4 0.7 0.081 12.2 0.0 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 EON33602.1 - 9.3e-05 22.2 1.9 0.00045 19.9 1.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON33602.1 - 0.00066 19.0 4.4 0.013 14.8 2.6 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON33602.1 - 0.0019 17.0 3.6 0.024 13.3 1.1 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EON33602.1 - 0.0021 17.5 0.2 0.0034 16.8 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON33602.1 - 0.11 11.8 0.8 0.46 9.7 0.4 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EON33602.1 - 0.88 8.6 6.5 0.16 11.0 2.5 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Sdh_cyt PF01127.22 EON33603.1 - 1.3e-14 54.3 2.0 1.7e-14 53.9 2.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Cation_ATPase_C PF00689.21 EON33603.1 - 0.00034 20.4 0.1 0.0004 20.1 0.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus CybS PF05328.12 EON33603.1 - 0.0048 16.6 0.2 0.0068 16.1 0.2 1.5 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 EON33604.1 - 1.3e-23 83.3 0.9 1.7e-23 82.9 0.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ferric_reduct PF01794.19 EON33604.1 - 0.0055 16.8 3.4 0.011 15.8 3.4 1.7 1 1 0 1 1 1 1 Ferric reductase like transmembrane component Fumarate_red_C PF02300.17 EON33604.1 - 0.0078 16.3 4.1 0.059 13.5 3.9 1.9 1 1 1 2 2 2 1 Fumarate reductase subunit C Fumarate_red_D PF02313.17 EON33604.1 - 0.015 15.4 1.4 0.022 14.9 1.4 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit D Troponin-I_N PF11636.8 EON33604.1 - 0.081 12.9 0.6 0.14 12.2 0.6 1.3 1 0 0 1 1 1 0 Troponin I residues 1-32 DUF4131 PF13567.6 EON33604.1 - 0.47 10.1 4.3 1.6 8.4 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) dCMP_cyt_deam_2 PF08211.12 EON33605.1 - 1.9e-10 41.0 2.2 3.6e-07 30.5 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 EON33605.1 - 5.4e-09 35.9 0.1 6.3e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glycos_transf_3 PF00591.21 EON33606.1 - 2e-29 102.9 2.2 3.3e-29 102.3 2.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 EON33606.1 - 7e-19 67.3 0.4 2.4e-18 65.6 0.2 2.0 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 EON33606.1 - 9.3e-19 67.0 1.2 1.2e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Biotin_lipoyl PF00364.22 EON33606.1 - 0.065 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Biotin-requiring enzyme A_deaminase PF00962.22 EON33607.1 - 3.8e-90 302.5 0.0 4.5e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase BUD22 PF09073.10 EON33608.1 - 0.0051 16.2 1.2 0.0064 15.9 1.2 1.1 1 0 0 1 1 1 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 EON33608.1 - 1.9 8.7 15.6 3 8.0 15.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NLPC_P60 PF00877.19 EON33609.1 - 3.9e-25 87.9 0.0 6.1e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family WXG100 PF06013.12 EON33609.1 - 0.00053 20.2 0.6 0.0088 16.2 0.9 2.4 1 1 1 2 2 2 1 Proteins of 100 residues with WXG INCA1 PF15142.6 EON33609.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 INCA1 T7SS_ESX_EspC PF10824.8 EON33610.1 - 0.0024 18.3 0.9 0.0027 18.1 0.9 1.1 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm UPRTase PF14681.6 EON33611.1 - 2.9e-58 196.7 0.0 3.4e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EON33611.1 - 4.3e-11 42.6 0.0 6.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mucin PF01456.17 EON33612.1 - 0.034 14.1 11.7 0.05 13.6 11.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EON33612.1 - 0.25 9.5 10.5 0.3 9.2 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PNP_UDP_1 PF01048.20 EON33613.1 - 1.6e-42 145.4 4.0 2e-42 145.0 4.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ECH_1 PF00378.20 EON33614.1 - 2.1e-24 86.2 0.0 2.5e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON33614.1 - 5.4e-11 42.6 0.0 6.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M20 PF01546.28 EON33615.1 - 1.9e-27 96.3 0.3 2.3e-27 96.0 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON33615.1 - 0.0018 18.2 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain AIG2_2 PF13772.6 EON33616.1 - 4.6e-24 84.6 0.0 5.8e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 EON33616.1 - 6.6e-09 36.4 0.0 8.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Pyr_redox_2 PF07992.14 EON33617.1 - 5.7e-59 199.7 4.0 7.4e-59 199.4 4.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EON33617.1 - 8e-24 84.0 0.1 2.5e-23 82.4 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EON33617.1 - 8.9e-23 80.7 4.6 1.1e-16 61.1 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON33617.1 - 1.5e-10 40.7 7.1 9.7e-09 34.8 0.2 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EON33617.1 - 4.2e-10 39.4 3.6 1.5e-08 34.2 3.6 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON33617.1 - 4.2e-10 39.6 3.3 1.8e-06 27.6 1.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EON33617.1 - 2.5e-07 29.8 4.1 0.0021 16.8 2.3 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EON33617.1 - 2.3e-06 27.7 4.4 0.0039 17.4 0.8 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EON33617.1 - 6.4e-06 26.6 0.4 0.027 14.9 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EON33617.1 - 1.4e-05 24.5 8.5 0.0025 17.2 1.4 3.3 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EON33617.1 - 5.9e-05 22.4 0.5 0.00016 21.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EON33617.1 - 0.00015 20.9 3.4 0.16 11.0 0.1 3.3 2 1 1 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 EON33617.1 - 0.0002 20.4 0.5 0.00041 19.3 0.5 1.5 1 0 0 1 1 1 1 Tryptophan halogenase XdhC_C PF13478.6 EON33617.1 - 0.00099 19.6 0.6 0.47 11.0 0.1 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain DAO PF01266.24 EON33617.1 - 0.0034 17.0 21.7 0.14 11.7 6.0 4.6 4 1 1 5 5 5 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON33617.1 - 0.0037 16.6 9.7 0.022 14.0 0.4 3.6 3 1 1 4 4 4 1 FAD binding domain FAD_binding_2 PF00890.24 EON33617.1 - 0.0052 15.9 17.2 0.0073 15.4 3.4 4.2 4 1 1 5 5 5 1 FAD binding domain Amino_oxidase PF01593.24 EON33617.1 - 0.0053 16.1 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EON33617.1 - 0.011 16.0 2.2 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 EON33617.1 - 0.042 13.7 4.7 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON33617.1 - 0.046 13.7 12.0 0.47 10.4 0.6 3.5 4 0 0 4 4 3 0 FAD-NAD(P)-binding ATPgrasp_N PF18130.1 EON33617.1 - 0.081 13.5 0.8 2.8 8.5 0.1 2.8 2 1 0 2 2 2 0 ATP-grasp N-terminal domain 2-Hacid_dh_C PF02826.19 EON33617.1 - 0.16 11.3 0.8 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EON33617.1 - 0.33 10.5 1.9 8.3 5.9 0.7 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.15 EON33617.1 - 0.37 10.6 3.7 5.1 6.9 0.0 2.7 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein MerR-DNA-bind PF09278.11 EON33618.1 - 0.97 10.0 2.2 0.8 10.3 0.1 1.9 2 0 0 2 2 2 0 MerR, DNA binding Staygreen PF12638.7 EON33619.1 - 0.049 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Staygreen protein TPR_21 PF09976.9 EON33619.1 - 0.17 11.6 1.2 0.23 11.2 0.9 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain FGGY_N PF00370.21 EON33620.1 - 1.2e-70 237.9 0.0 1.8e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EON33620.1 - 1.5e-66 223.9 0.2 2.7e-66 223.1 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EON33620.1 - 0.00081 19.0 0.9 0.006 16.1 0.1 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DAO PF01266.24 EON33621.1 - 2.8e-51 175.2 5.8 4.3e-51 174.5 5.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EON33621.1 - 2.3e-31 108.3 0.0 5.2e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EON33621.1 - 7.3e-11 41.8 8.4 1e-05 24.8 2.1 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EON33621.1 - 2.1e-10 40.6 1.9 1.3e-08 34.6 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON33621.1 - 5.1e-10 39.1 2.8 2.2e-09 37.0 2.8 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON33621.1 - 9.5e-08 31.6 0.8 4.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON33621.1 - 0.00019 20.7 1.1 0.00032 19.9 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EON33621.1 - 0.0018 18.4 1.2 0.0063 16.7 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EON33621.1 - 0.007 15.7 0.4 0.013 14.8 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EON33621.1 - 0.0095 16.5 1.7 0.0095 16.5 1.7 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EON33621.1 - 0.011 15.0 0.3 0.011 15.0 0.3 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EON33621.1 - 0.011 14.5 2.4 0.011 14.5 2.4 1.6 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 EON33621.1 - 0.014 15.3 1.0 0.023 14.6 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EON33621.1 - 0.034 13.4 0.3 0.24 10.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EON33621.1 - 0.13 11.3 2.8 0.26 10.3 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.15 EON33621.1 - 0.19 10.2 0.4 13 4.2 0.1 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyridox_ox_2 PF12900.7 EON33622.1 - 7e-23 81.2 0.1 8.3e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EON33622.1 - 3.6e-06 27.1 0.0 6.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase H2TH PF06831.14 EON33623.1 - 1.6e-12 47.2 0.0 2.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EON33623.1 - 4.1e-08 33.8 0.0 7.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 EON33623.1 - 0.0034 17.2 4.4 0.0096 15.8 4.4 1.8 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS MgsA_C PF12002.8 EON33623.1 - 0.19 11.7 0.4 0.35 10.8 0.4 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Nudix_N_2 PF14803.6 EON33623.1 - 0.43 10.5 2.7 0.9 9.5 2.7 1.6 1 0 0 1 1 1 0 Nudix N-terminal PknG_rubred PF16919.5 EON33623.1 - 0.88 9.7 4.7 1.7 8.8 3.1 2.1 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain DEAD_assoc PF08494.11 EON33624.1 - 1.4e-75 253.3 0.6 4.3e-75 251.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/H associated DEAD PF00270.29 EON33624.1 - 9e-26 90.7 0.0 1.9e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON33624.1 - 5.3e-14 52.5 0.0 1.5e-12 47.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HTH_42 PF06224.12 EON33624.1 - 1.7e-09 37.7 26.6 1.5e-07 31.2 9.4 3.0 2 0 0 2 2 2 2 Winged helix DNA-binding domain ResIII PF04851.15 EON33624.1 - 3.3e-07 30.5 0.0 7.9e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EON33624.1 - 0.0058 16.2 0.2 0.017 14.7 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON33624.1 - 0.013 15.8 0.0 0.075 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EON33624.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein CbtB PF09489.10 EON33625.1 - 5.1e-15 55.3 3.9 5.1e-15 55.3 3.9 1.7 1 1 1 2 2 2 1 Probable cobalt transporter subunit (CbtB) CbtA PF09490.10 EON33626.1 - 5.2e-67 226.2 18.5 6e-67 226.0 18.5 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) His_Phos_1 PF00300.22 EON33627.1 - 1.2e-13 51.2 0.0 1.4e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acyl-CoA_dh_1 PF00441.24 EON33628.1 - 4.7e-39 134.0 3.4 6.4e-39 133.5 3.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON33628.1 - 1.7e-22 79.4 0.0 3.3e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON33628.1 - 4.6e-14 52.8 0.1 7.6e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33628.1 - 6.7e-13 49.3 0.1 3.5e-12 47.0 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 EON33628.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PPK2 PF03976.14 EON33629.1 - 2.8e-95 318.2 0.1 3.2e-95 318.0 0.1 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) E1-E2_ATPase PF00122.20 EON33630.1 - 1.8e-47 161.2 3.2 1.8e-47 161.2 3.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EON33630.1 - 3.1e-24 85.7 3.3 3.1e-24 85.7 3.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EON33630.1 - 6.7e-18 64.6 0.0 1.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EON33630.1 - 3.3e-14 53.7 10.2 3.3e-13 50.4 8.2 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EON33630.1 - 5.8e-14 51.5 0.0 1.9e-13 49.9 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EON33630.1 - 0.00011 22.0 0.7 0.00011 22.0 0.7 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 EON33630.1 - 0.0034 17.2 0.1 0.0034 17.2 0.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal DUF4191 PF13829.6 EON33630.1 - 0.73 9.1 5.9 1.2 8.4 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DAGK_cat PF00781.24 EON33631.1 - 1.7e-16 60.0 0.0 2.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EON33631.1 - 7.9e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase EI24 PF07264.11 EON33632.1 - 0.58 10.4 12.6 0.75 10.0 5.6 3.2 2 2 1 3 3 3 0 Etoposide-induced protein 2.4 (EI24) DUF3185 PF11381.8 EON33633.1 - 0.012 15.6 8.0 0.034 14.1 8.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) DUF4383 PF14325.6 EON33633.1 - 0.073 13.3 8.5 0.068 13.4 7.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) DUF2127 PF09900.9 EON33633.1 - 0.13 12.5 15.9 0.21 11.9 15.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2127) Tetraspanin PF00335.20 EON33633.1 - 2.2 7.9 6.9 2.9 7.5 6.9 1.3 1 1 0 1 1 1 0 Tetraspanin family Ald_Xan_dh_C2 PF02738.18 EON33634.1 - 1.2e-145 486.1 11.8 1.5e-145 485.8 10.6 1.6 2 0 0 2 2 2 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 EON33634.1 - 1.2e-26 93.2 0.0 3.1e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EON33634.1 - 2.3e-25 88.4 0.1 4.6e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EON33634.1 - 6.3e-06 26.1 0.8 2e-05 24.5 0.8 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EON33634.1 - 0.00015 21.8 0.1 0.008 16.2 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 EON33634.1 - 0.043 13.9 0.3 0.18 11.9 0.3 2.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FAD_binding_5 PF00941.21 EON33635.1 - 1.4e-13 51.0 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase MFS_1 PF07690.16 EON33636.1 - 2.4e-37 128.7 53.9 2.4e-37 128.7 53.9 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5325 PF17259.2 EON33636.1 - 0.1 12.5 0.0 0.1 12.5 0.0 5.3 5 1 1 6 6 6 0 Family of unknown function (DUF5325) Lipase_GDSL_2 PF13472.6 EON33637.1 - 6.1e-24 85.4 2.4 9.6e-24 84.7 2.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EON33637.1 - 8.1e-14 52.1 0.0 9.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CPSase_L_D2 PF02786.17 EON33638.1 - 7e-71 238.1 0.4 1.2e-70 237.3 0.4 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EON33638.1 - 8e-53 179.1 0.0 2.6e-52 177.5 0.0 1.8 2 0 0 2 2 2 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EON33638.1 - 1.3e-38 131.9 0.1 3.6e-38 130.5 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EON33638.1 - 2e-36 124.4 0.0 6.5e-36 122.7 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EON33638.1 - 9.6e-26 90.9 0.0 4e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 HMGL-like Biotin_lipoyl PF00364.22 EON33638.1 - 3.6e-11 42.7 1.0 8.1e-11 41.6 1.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EON33638.1 - 3.9e-10 39.6 0.0 7.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EON33638.1 - 8.1e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EON33638.1 - 4.1e-05 23.3 2.6 0.0015 18.3 0.3 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 EON33638.1 - 0.00019 21.4 0.8 0.00058 19.8 0.5 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 EON33638.1 - 0.00056 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 EON33638.1 - 0.019 14.8 0.4 0.048 13.5 0.4 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Amidohydro_2 PF04909.14 EON33638.1 - 0.035 13.9 0.3 0.23 11.2 0.1 2.5 3 0 0 3 3 3 0 Amidohydrolase ATP-grasp_4 PF13535.6 EON33638.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.6 EON33638.1 - 1.1 9.9 3.1 5.9 7.6 0.3 2.9 3 0 0 3 3 2 0 HlyD family secretion protein Transthyretin PF00576.21 EON33639.1 - 3.5e-33 114.6 0.0 3.9e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family bMG3 PF11974.8 EON33639.1 - 2.1e-05 24.5 0.3 2.6e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain CarboxypepD_reg PF13620.6 EON33639.1 - 0.00036 20.8 0.6 0.00046 20.4 0.6 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EON33639.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 SdrD B-like domain OHCU_decarbox PF09349.10 EON33640.1 - 3.8e-40 137.9 1.1 4.3e-40 137.7 1.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase RPT PF13446.6 EON33640.1 - 0.12 12.4 0.8 2.5 8.1 0.1 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein NTP_transf_3 PF12804.7 EON33641.1 - 8.9e-18 65.2 8.6 1.1e-17 64.8 8.6 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain HPP PF04982.13 EON33641.1 - 0.81 9.9 7.7 2.4 8.4 6.3 2.3 1 1 2 3 3 3 0 HPP family Ald_Xan_dh_C2 PF02738.18 EON33643.1 - 3e-108 362.7 0.0 6.7e-83 279.0 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 EON33643.1 - 1.5e-17 64.0 0.1 4e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 EON33644.1 - 1.2e-47 161.8 0.0 2.7e-47 160.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EON33644.1 - 3.4e-18 65.7 0.2 5.9e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EON33645.1 - 1.7e-29 101.7 0.1 1.7e-29 101.7 0.1 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 EON33645.1 - 1.5e-06 28.0 0.2 1.5e-06 28.0 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EON33645.1 - 9.4e-05 22.4 0.1 0.00016 21.6 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pyr_redox_2 PF07992.14 EON33646.1 - 7.6e-50 169.8 0.0 9.5e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON33646.1 - 5.3e-11 42.9 0.6 7.5e-05 23.2 0.2 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EON33646.1 - 7.3e-05 22.5 3.4 0.0029 17.3 3.4 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON33646.1 - 0.00013 22.2 0.1 0.0007 19.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EON33646.1 - 0.001 17.9 0.5 0.015 14.0 0.0 2.4 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 EON33646.1 - 0.0051 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EON33646.1 - 0.0062 15.8 1.6 0.35 10.1 0.0 3.2 2 1 1 3 3 3 1 FAD binding domain TrkA_N PF02254.18 EON33646.1 - 0.008 16.4 0.2 1.5 9.1 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.6 EON33646.1 - 0.013 15.5 0.8 0.44 10.5 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EON33646.1 - 0.013 14.8 0.0 0.41 9.9 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON33646.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 EON33646.1 - 0.052 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EON33646.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 EON33646.1 - 0.085 11.9 0.1 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EON33646.1 - 0.17 12.3 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 EON33646.1 - 0.23 10.5 1.6 0.63 9.1 0.0 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A NMO PF03060.15 EON33647.1 - 1.9e-44 152.4 0.1 6.9e-44 150.6 0.1 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EON33647.1 - 1.8e-08 33.8 1.5 2.9e-08 33.1 1.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EON33647.1 - 0.0024 17.2 0.9 0.0033 16.8 0.9 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EON33647.1 - 0.0031 16.6 1.5 0.0064 15.5 1.5 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EON33647.1 - 0.061 12.8 0.4 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.17 EON33647.1 - 0.57 9.3 3.8 0.47 9.5 0.1 2.1 2 0 0 2 2 2 0 Conserved region in glutamate synthase Rhodanese PF00581.20 EON33648.1 - 1.3e-12 48.2 0.0 1.4e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain MarR_2 PF12802.7 EON33649.1 - 1.7e-10 40.6 0.8 3.6e-10 39.6 0.1 1.9 2 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 EON33649.1 - 0.00015 21.2 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EON33649.1 - 0.0085 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EON33649.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 EON33649.1 - 0.039 13.7 0.1 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_27 PF13463.6 EON33649.1 - 0.099 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain PAS_9 PF13426.7 EON33650.1 - 8.8e-17 61.3 0.0 6.1e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.26 EON33650.1 - 4.4e-14 52.9 0.0 2e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 EON33650.1 - 1.2e-13 51.1 0.1 2.4e-06 27.5 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EON33650.1 - 5.2e-11 42.7 0.0 6.4e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EON33650.1 - 7.1e-09 35.5 0.0 0.0016 18.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EON33650.1 - 2.3e-07 31.1 0.3 0.00036 20.8 0.1 2.6 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 EON33650.1 - 0.00079 19.4 0.2 0.0041 17.1 0.2 2.3 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EON33650.1 - 0.0015 18.4 0.0 0.0052 16.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain RMI2 PF16100.5 EON33650.1 - 0.039 13.8 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 RecQ-mediated genome instability protein 2 Acyl-CoA_dh_2 PF08028.11 EON33651.1 - 4.5e-23 82.0 6.9 4.5e-23 82.0 6.9 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EON33651.1 - 0.00081 19.6 1.7 0.00081 19.6 1.7 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON33651.1 - 0.0026 18.4 0.0 0.0074 16.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Rieske PF00355.26 EON33653.1 - 6.9e-21 74.0 0.0 1.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 EON33653.1 - 5.2e-17 62.5 1.0 7.2e-17 62.1 1.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Ring_hydroxyl_B PF00866.18 EON33654.1 - 2e-15 57.1 0.1 2.4e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Ring hydroxylating beta subunit SnoaL_4 PF13577.6 EON33654.1 - 0.022 14.9 0.2 0.033 14.3 0.2 1.4 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 EON33654.1 - 0.037 14.7 1.5 0.11 13.1 1.5 1.9 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 EON33654.1 - 0.071 13.5 1.4 0.14 12.6 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) adh_short_C2 PF13561.6 EON33655.1 - 1.1e-47 162.6 0.3 1.3e-47 162.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON33655.1 - 4.6e-43 147.0 0.2 5.8e-43 146.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON33655.1 - 8.4e-09 35.6 0.5 1.1e-08 35.2 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON33655.1 - 0.00041 19.9 0.2 0.00057 19.4 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON33655.1 - 0.00046 20.4 0.1 0.001 19.3 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EON33655.1 - 0.022 14.7 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EON33655.1 - 0.027 14.0 0.2 0.039 13.5 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family HTH_37 PF13744.6 EON33655.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GDP_Man_Dehyd PF16363.5 EON33655.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fer2 PF00111.27 EON33656.1 - 1.4e-11 44.2 4.3 1.6e-11 44.0 3.1 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 EON33656.1 - 8.1e-07 29.3 0.1 0.013 15.7 0.0 3.2 3 0 0 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EON33656.1 - 1.8e-06 28.5 0.1 3e-05 24.6 0.1 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EON33656.1 - 3.5e-06 27.3 0.0 2.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.6 EON33656.1 - 0.0016 18.4 0.3 0.0039 17.2 0.3 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EON33656.1 - 0.089 12.8 1.5 0.26 11.3 1.5 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Response_reg PF00072.24 EON33657.1 - 4.7e-24 84.7 0.0 7.3e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON33657.1 - 1.6e-14 53.2 0.1 2.7e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON33657.1 - 2.9e-10 39.6 0.4 5.2e-10 38.9 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33657.1 - 0.0027 17.2 0.2 0.0062 16.0 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 FleQ PF06490.11 EON33657.1 - 0.0048 17.3 0.0 0.0079 16.5 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ SieB PF14163.6 EON33657.1 - 0.0077 15.7 0.1 0.024 14.1 0.1 1.9 1 1 0 1 1 1 1 Super-infection exclusion protein B HTH_29 PF13551.6 EON33657.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 EON33657.1 - 0.044 13.6 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EON33657.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain cwf21 PF08312.12 EON33657.1 - 0.11 12.6 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 cwf21 domain Amidase PF01425.21 EON33659.1 - 6.2e-53 180.3 5.3 2.1e-51 175.3 5.3 2.2 1 1 0 1 1 1 1 Amidase EccE PF11203.8 EON33659.1 - 0.14 12.5 1.8 0.21 12.0 0.1 2.1 2 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE MFS_1 PF07690.16 EON33660.1 - 8.5e-43 146.6 58.9 2.2e-35 122.2 40.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavin_Reduct PF01613.18 EON33661.1 - 4.9e-29 101.4 0.0 7.2e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Flavin reductase like domain NADase_NGA PF07461.11 EON33661.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) SnoaL_4 PF13577.6 EON33662.1 - 6e-22 78.1 2.4 2e-21 76.4 2.4 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EON33662.1 - 3.4e-05 24.4 0.3 7e-05 23.4 0.3 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 EON33662.1 - 0.0074 16.5 0.1 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON33662.1 - 0.013 15.9 0.4 0.026 14.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) FMN_red PF03358.15 EON33663.1 - 1.7e-06 27.8 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase ptaRNA1_toxin PF12703.7 EON33663.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system Chon_Sulph_att PF06566.11 EON33663.1 - 0.36 10.7 3.5 11 5.8 0.0 2.8 1 1 2 3 3 3 0 Chondroitin sulphate attachment domain TPR_6 PF13174.6 EON33664.1 - 0.045 14.4 4.2 0.075 13.7 1.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EON33664.1 - 0.05 14.1 0.2 0.088 13.3 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TMEM220 PF15071.6 EON33664.1 - 0.076 13.8 0.2 0.24 12.2 0.0 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF1282 PF06930.12 EON33664.1 - 0.57 9.9 7.6 0.8 9.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) FA_desaturase PF00487.24 EON33664.1 - 5.1 6.9 6.9 6.6 6.5 6.7 1.4 1 1 0 1 1 1 0 Fatty acid desaturase DapB_C PF05173.14 EON33665.1 - 1e-28 99.8 0.0 1.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 EON33665.1 - 9.4e-24 83.9 0.6 3.4e-22 78.9 0.6 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus HTH_24 PF13412.6 EON33666.1 - 6.5e-17 60.8 0.5 9.6e-17 60.3 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 EON33666.1 - 5.9e-16 58.2 0.1 8.8e-16 57.6 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 EON33666.1 - 3.8e-15 55.4 3.4 3.8e-15 55.4 3.4 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 EON33666.1 - 2.4e-07 30.5 0.7 4.7e-07 29.5 0.7 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EON33666.1 - 3e-05 24.0 1.2 3e-05 24.0 1.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 EON33666.1 - 5.9e-05 22.9 1.1 0.00044 20.1 0.8 2.3 1 1 0 2 2 2 1 MarR family HTH_5 PF01022.20 EON33666.1 - 0.0051 16.7 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 EON33666.1 - 0.0092 15.9 0.0 0.024 14.5 0.1 1.7 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EON33666.1 - 0.019 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_10 PF04967.12 EON33666.1 - 0.022 14.5 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain HTH_27 PF13463.6 EON33666.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain RP-C PF03428.13 EON33666.1 - 0.054 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_CodY PF08222.11 EON33666.1 - 0.061 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain TetR_C_24 PF17932.1 EON33666.1 - 0.092 13.0 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TrmB PF01978.19 EON33666.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB AlaDh_PNT_C PF01262.21 EON33667.1 - 4.2e-77 258.2 2.3 6.2e-77 257.7 2.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EON33667.1 - 5.3e-46 156.3 0.1 9.9e-46 155.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox PF00070.27 EON33667.1 - 2.2e-05 24.9 0.8 6.9e-05 23.3 0.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EON33667.1 - 6.3e-05 22.3 0.2 0.00014 21.3 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON33667.1 - 0.0011 18.4 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EON33667.1 - 0.0046 16.1 0.7 0.0065 15.6 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EON33667.1 - 0.025 13.9 4.4 0.036 13.4 4.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EON33667.1 - 0.051 13.5 2.2 0.11 12.4 2.2 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EON33667.1 - 0.051 12.3 1.6 0.072 11.8 1.6 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.15 EON33667.1 - 0.12 12.5 2.3 0.17 12.0 1.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.6 EON33667.1 - 0.18 11.0 0.2 0.28 10.4 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TANGO2 PF05742.12 EON33668.1 - 2.7e-50 171.8 0.0 3.2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 DUF294_C PF10335.9 EON33669.1 - 2.7e-26 92.1 0.2 4.5e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain DUF294 PF03445.13 EON33669.1 - 3.4e-20 72.3 0.0 5.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 CBS PF00571.28 EON33669.1 - 0.00079 19.8 3.1 1.1 9.7 0.6 2.7 2 0 0 2 2 2 2 CBS domain Trypsin_2 PF13365.6 EON33670.1 - 0.00065 20.6 1.2 0.00095 20.1 1.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EON33670.1 - 0.0038 17.1 0.1 0.81 9.4 0.1 2.2 2 0 0 2 2 2 2 Trypsin PRC PF05239.16 EON33670.1 - 0.039 14.0 0.6 0.93 9.6 0.1 3.1 3 1 0 3 3 3 0 PRC-barrel domain RNase_PH PF01138.21 EON33671.1 - 1.9e-36 125.5 0.0 2.1e-17 63.9 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 EON33671.1 - 1.4e-20 73.5 0.6 3.7e-20 72.2 0.6 1.8 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 EON33671.1 - 8.3e-13 48.5 0.9 2.2e-12 47.1 0.9 1.7 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 EON33671.1 - 5.4e-10 38.9 0.6 1.9e-09 37.2 0.6 2.0 1 0 0 1 1 1 1 KH domain RNase_PH_C PF03725.15 EON33671.1 - 2.6e-06 27.4 0.8 0.0018 18.3 0.1 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 Ribosomal_S15 PF00312.22 EON33672.1 - 1.9e-37 127.3 2.8 2.1e-37 127.2 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 FAD_syn PF06574.12 EON33673.1 - 1.7e-49 167.7 0.1 2.7e-49 167.1 0.1 1.3 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 EON33673.1 - 5.5e-34 116.8 0.0 1.3e-33 115.6 0.0 1.6 2 0 0 2 2 2 1 Riboflavin kinase CTP_transf_like PF01467.26 EON33673.1 - 6.8e-06 26.3 0.0 0.00036 20.8 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like AP_endonuc_2 PF01261.24 EON33673.1 - 0.02 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Fe_dep_repr_C PF02742.15 EON33674.1 - 1.1e-30 105.5 0.1 6e-30 103.1 0.1 2.0 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 EON33674.1 - 4.2e-19 68.5 0.0 6.7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain FeoA PF04023.14 EON33674.1 - 4.8e-18 65.2 0.1 2.4e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 FeoA domain HTH_Crp_2 PF13545.6 EON33674.1 - 3.2e-05 23.8 0.0 7.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 EON33674.1 - 5.8e-05 22.9 0.0 0.0002 21.2 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EON33674.1 - 0.00015 21.2 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON33674.1 - 0.00021 21.1 0.1 0.00076 19.3 0.0 2.0 2 0 0 2 2 2 1 MarR family GntR PF00392.21 EON33674.1 - 0.00063 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 EON33674.1 - 0.00069 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 EON33674.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 EON33674.1 - 0.0033 17.2 0.1 0.0078 16.0 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain TrmB PF01978.19 EON33674.1 - 0.0036 17.2 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 EON33674.1 - 0.0094 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 EON33674.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_IclR PF09339.10 EON33674.1 - 0.016 15.0 0.9 0.055 13.3 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Rrf2 PF02082.20 EON33674.1 - 0.021 15.2 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 EON33674.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain DUF2742 PF10888.8 EON33674.1 - 0.041 14.1 0.6 0.48 10.7 0.0 2.8 3 2 1 4 4 4 0 Protein of unknown function (DUF2742) HTH_5 PF01022.20 EON33674.1 - 0.044 13.6 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Penicillinase_R PF03965.16 EON33674.1 - 0.047 14.1 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 Penicillinase repressor HTH_AsnC-type PF13404.6 EON33674.1 - 0.066 13.0 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_DeoR PF08220.12 EON33674.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ribosomal_S25 PF03297.15 EON33674.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 S25 ribosomal protein HTH_1 PF00126.27 EON33674.1 - 0.17 11.9 1.5 0.77 9.8 0.5 2.6 3 1 0 3 3 2 0 Bacterial regulatory helix-turn-helix protein, lysR family TruB_N PF01509.18 EON33675.1 - 1.9e-49 167.9 0.0 2.9e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C PF09142.11 EON33675.1 - 5.3e-19 67.7 0.1 3.9e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal TruB_C_2 PF16198.5 EON33675.1 - 8.7e-14 51.4 0.1 1.7e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PseudoU_synth_2 PF00849.22 EON33675.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA pseudouridylate synthase DKCLD PF08068.12 EON33675.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain 4PPT_N PF17837.1 EON33676.1 - 1.2e-27 95.8 0.2 2.1e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 EON33676.1 - 1.1e-11 44.9 0.0 1.5e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Metallophos PF00149.28 EON33677.1 - 4.4e-17 63.2 0.0 6.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EON33677.1 - 7.8e-07 29.4 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain RRXRR PF14239.6 EON33677.1 - 3.7 7.4 8.4 6.4 6.6 8.4 1.3 1 0 0 1 1 1 0 RRXRR protein MatE PF01554.18 EON33678.1 - 2.9e-34 118.0 29.9 1.4e-20 73.5 6.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EON33678.1 - 5.7e-07 29.7 9.6 5.7e-07 29.7 9.6 4.8 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DHH PF01368.20 EON33679.1 - 1.6e-11 44.3 0.1 3.2e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 EON33679.1 - 1.6e-11 44.7 0.1 2.7e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 DHHA1 domain DUF4646 PF15496.6 EON33679.1 - 0.0094 16.6 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) RBFA PF02033.18 EON33680.1 - 2.4e-25 89.0 0.0 2.9e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A LPD22 PF18834.1 EON33680.1 - 0.65 10.3 8.8 0.26 11.5 5.7 2.0 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 GTP_EFTU PF00009.27 EON33681.1 - 3.5e-36 124.6 1.8 1.8e-34 119.0 1.8 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EON33681.1 - 6.4e-34 116.2 0.6 2e-33 114.7 0.6 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EON33681.1 - 1.8e-08 34.6 1.0 0.0025 18.2 0.1 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON33681.1 - 2.2e-08 34.2 0.2 5.5e-08 32.9 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EON33681.1 - 1.9e-07 30.9 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ras family IF2_N PF04760.15 EON33681.1 - 3e-06 26.9 0.0 7.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Roc PF08477.13 EON33681.1 - 0.00027 21.1 0.0 0.00044 20.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EON33681.1 - 0.0003 20.3 0.0 0.0013 18.2 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EON33681.1 - 0.0073 15.9 0.1 0.028 13.9 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Glyco_hydro_3_C PF01915.22 EON33681.1 - 0.22 11.5 1.1 1.6 8.6 0.1 2.6 2 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF448 PF04296.13 EON33682.1 - 1.2e-19 69.9 0.0 1.4e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF448) PSK_trans_fac PF07704.11 EON33682.1 - 0.085 13.6 1.3 0.27 12.0 1.3 1.9 1 1 0 1 1 1 0 Rv0623-like transcription factor KH_5 PF13184.6 EON33683.1 - 2e-23 82.2 0.1 1.1e-22 79.8 0.0 2.4 2 0 0 2 2 2 1 NusA-like KH domain NusA_N PF08529.11 EON33683.1 - 8.3e-19 68.1 0.0 7.5e-09 36.0 0.0 2.4 1 1 1 2 2 2 2 NusA N-terminal domain KH_1 PF00013.29 EON33683.1 - 0.00051 19.8 0.0 0.3 10.9 0.0 2.6 1 1 1 2 2 2 2 KH domain KH_2 PF07650.17 EON33683.1 - 0.0012 18.7 0.7 0.13 12.1 0.0 3.1 3 1 0 3 3 3 1 KH domain S1 PF00575.23 EON33683.1 - 0.0068 16.7 0.2 0.0068 16.7 0.2 2.2 2 0 0 2 2 2 1 S1 RNA binding domain DUF150 PF02576.17 EON33684.1 - 2.8e-14 53.3 1.1 9.1e-14 51.6 0.2 2.1 2 0 0 2 2 2 1 RimP N-terminal domain DUF150_C PF17384.2 EON33684.1 - 1.7e-05 24.9 0.2 3.5e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 RimP C-terminal SH3 domain RBD PF02196.15 EON33684.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF4439 PF14530.6 EON33686.1 - 8.1e-38 130.1 8.1 9.5e-38 129.9 8.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) BAT PF15915.5 EON33686.1 - 0.014 15.3 1.1 0.014 15.3 1.1 2.2 1 1 0 2 2 2 0 GAF and HTH_10 associated domain tRNA-synt_2b PF00587.25 EON33687.1 - 7e-36 123.9 0.0 9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EON33687.1 - 2.4e-17 63.1 0.0 6.1e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 EON33687.1 - 2.5e-16 59.6 0.0 8e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain DUF1198 PF06711.11 EON33687.1 - 0.044 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) H2O2_YaaD PF03883.14 EON33688.1 - 1.6e-38 132.5 0.0 1.9e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA Putative_PNPOx PF01243.20 EON33689.1 - 1.1e-10 41.6 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 EON33690.1 - 1.2e-47 162.6 52.9 1.8e-45 155.4 51.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EON33690.1 - 0.13 11.1 16.6 0.0077 15.1 7.2 2.6 3 0 0 3 3 3 0 MFS_1 like family TP_methylase PF00590.20 EON33691.1 - 1.8e-47 162.1 2.0 1.8e-47 162.1 2.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EON33691.1 - 2.8e-22 79.1 0.1 7.5e-22 77.7 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EON33691.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FA_desaturase_2 PF03405.14 EON33692.1 - 9.8e-77 258.0 0.1 1.1e-76 257.7 0.1 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Response_reg PF00072.24 EON33693.1 - 9.5e-23 80.5 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON33693.1 - 1.6e-16 59.6 0.2 2.7e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON33693.1 - 1.5e-07 31.0 0.1 2.7e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33693.1 - 0.00028 20.4 0.2 0.00057 19.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EON33693.1 - 0.012 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 EON33693.1 - 0.042 14.3 0.1 0.072 13.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EON33693.1 - 0.097 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3071 PF11268.8 EON33693.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) GAF_2 PF13185.6 EON33694.1 - 4.6e-14 52.9 3.1 1.9e-12 47.6 0.5 3.1 2 1 0 2 2 2 1 GAF domain HisKA_3 PF07730.13 EON33694.1 - 8.5e-13 48.6 2.2 8.5e-13 48.6 2.2 2.6 3 0 0 3 3 3 1 Histidine kinase GAF PF01590.26 EON33694.1 - 2.9e-11 44.1 0.3 7.3e-10 39.6 0.1 2.7 2 1 0 2 2 2 1 GAF domain GAF_3 PF13492.6 EON33694.1 - 1.9e-06 28.2 0.1 0.00084 19.7 0.0 3.1 2 1 0 2 2 2 1 GAF domain HATPase_c PF02518.26 EON33694.1 - 1.2e-05 25.8 0.1 4.2e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EON33694.1 - 0.0032 17.4 0.1 0.01 15.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EON33694.1 - 0.032 14.1 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpoVT_C PF15714.5 EON33694.1 - 0.18 11.8 0.0 0.52 10.4 0.0 1.7 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor GATase_3 PF07685.14 EON33695.1 - 2.3e-22 79.6 0.0 3.4e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 EON33695.1 - 1.3e-18 67.3 0.0 4.6e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EON33695.1 - 3.4e-12 46.6 0.2 4.2e-06 26.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain DJ-1_PfpI PF01965.24 EON33695.1 - 0.0034 17.2 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family MobB PF03205.14 EON33695.1 - 0.0066 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SNO PF01174.19 EON33695.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 SNO glutamine amidotransferase family PRK PF00485.18 EON33695.1 - 0.3 10.8 0.6 15 5.3 0.2 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CobA_CobO_BtuR PF02572.15 EON33696.1 - 1.6e-59 201.1 0.0 1.8e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_lid_2 PF17863.1 EON33697.1 - 5e-17 61.5 3.7 1.5e-16 59.9 3.7 1.9 1 0 0 1 1 1 1 AAA lid domain VWA_2 PF13519.6 EON33697.1 - 3e-14 53.6 0.0 6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 EON33697.1 - 8.7e-12 44.9 0.3 3.4e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EON33697.1 - 3e-11 43.5 0.0 6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) VWA PF00092.28 EON33697.1 - 4.2e-11 43.4 0.0 7.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain MCM PF00493.23 EON33697.1 - 2.4e-05 23.6 0.0 0.0001 21.5 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 EON33697.1 - 0.001 18.8 0.1 0.0035 17.1 0.1 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain VWA_3 PF13768.6 EON33697.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_3 PF07726.11 EON33697.1 - 0.06 13.2 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PV-1 PF06637.11 EON33697.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) AAA_16 PF13191.6 EON33697.1 - 0.64 10.4 6.5 0.5 10.7 0.6 3.2 2 1 1 3 3 3 0 AAA ATPase domain Acetyltransf_10 PF13673.7 EON33698.1 - 2.1e-10 40.6 0.0 2.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON33698.1 - 1.1e-05 25.6 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON33698.1 - 1.3e-05 25.5 0.0 1.7e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON33698.1 - 0.00017 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON33698.1 - 0.0094 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EON33698.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 1 1 0 1 1 1 0 FR47-like protein Mqo PF06039.15 EON33699.1 - 8.3e-221 733.7 0.0 9.5e-221 733.5 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 EON33699.1 - 5.9e-09 36.0 0.0 1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON33699.1 - 0.0099 15.2 0.8 0.03 13.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Hydrolase_4 PF12146.8 EON33700.1 - 2.5e-15 56.4 0.1 3.3e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EON33700.1 - 4.8e-11 43.7 11.7 4.8e-11 43.7 11.7 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON33700.1 - 2.9e-08 33.7 0.1 5.3e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 EON33700.1 - 0.00081 19.0 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 EON33700.1 - 0.0029 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EON33700.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 EON33700.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 EON33700.1 - 0.17 11.4 0.5 0.92 8.9 0.0 2.4 3 1 0 3 3 3 0 Prolyl oligopeptidase family Pyr_redox_2 PF07992.14 EON33701.1 - 3e-42 144.9 1.0 3.9e-42 144.5 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EON33701.1 - 3.6e-27 94.8 0.1 7.2e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EON33701.1 - 9.2e-14 51.8 0.0 2.9e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EON33701.1 - 4.4e-07 29.4 0.0 6.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON33701.1 - 7.9e-05 22.0 0.0 0.00045 19.5 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EON33701.1 - 0.00018 21.5 0.5 0.53 10.3 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EON33701.1 - 0.073 11.8 0.0 5.5 5.6 0.0 2.3 2 1 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 EON33701.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 EON33702.1 - 1.1e-17 64.6 0.8 1.8e-17 63.8 0.8 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON33702.1 - 1.3e-14 55.4 9.9 1.5e-14 55.1 9.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON33702.1 - 1.7e-09 37.3 0.6 2.8e-09 36.6 0.6 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PP2C_2 PF13672.6 EON33702.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C GATase_3 PF07685.14 EON33703.1 - 4.7e-41 140.6 0.0 6.7e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 EON33703.1 - 1.3e-20 73.7 0.0 2.7e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EON33703.1 - 5e-18 65.7 0.0 4.5e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain DJ-1_PfpI PF01965.24 EON33703.1 - 0.0019 18.0 0.1 0.0054 16.5 0.1 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family RCC1 PF00415.18 EON33704.1 - 6.3e-42 142.0 34.6 4.6e-08 33.5 0.8 8.3 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 EON33704.1 - 1e-38 133.2 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON33704.1 - 1.4e-18 67.1 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 EON33704.1 - 2.8e-14 52.5 49.8 5.6e-06 26.0 4.0 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat APH PF01636.23 EON33704.1 - 1.6e-07 31.5 0.1 0.0046 16.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1459 PF07312.11 EON33704.1 - 0.027 14.7 8.8 3.2 8.0 0.3 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1459) DUF3040 PF11239.8 EON33704.1 - 0.093 13.0 6.4 1.2 9.5 1.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Kelch_6 PF13964.6 EON33704.1 - 0.29 11.5 6.6 9 6.8 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Peptidase_M24 PF00557.24 EON33705.1 - 8.2e-54 182.5 0.6 9.5e-54 182.3 0.6 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Peripla_BP_2 PF01497.18 EON33706.1 - 5e-37 127.7 0.0 8.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 EON33707.1 - 8.5e-89 297.6 39.9 1.1e-88 297.3 39.9 1.1 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EON33707.1 - 6.4 6.2 34.7 0.048 13.1 25.6 2.1 2 1 0 2 2 2 0 ABC 3 transport family ABC_tran PF00005.27 EON33708.1 - 1.7e-33 116.1 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON33708.1 - 1.2e-10 41.2 0.0 1.4e-05 24.7 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON33708.1 - 4.8e-10 39.7 0.1 4.8e-05 23.3 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EON33708.1 - 0.00011 21.1 1.5 0.0042 15.9 0.1 2.4 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 EON33708.1 - 0.00033 21.2 0.0 0.00046 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON33708.1 - 0.00037 20.2 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON33708.1 - 0.00069 19.7 0.1 0.0019 18.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EON33708.1 - 0.00074 19.9 0.3 0.0014 19.1 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EON33708.1 - 0.00079 19.7 0.1 0.002 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EON33708.1 - 0.0012 18.5 0.5 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EON33708.1 - 0.0022 17.8 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON33708.1 - 0.0024 17.8 0.1 0.004 17.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EON33708.1 - 0.0037 17.7 0.0 0.015 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EON33708.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EON33708.1 - 0.0081 16.3 0.1 0.048 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON33708.1 - 0.029 14.6 0.7 0.14 12.4 0.7 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EON33708.1 - 0.039 14.2 0.1 0.46 10.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EON33708.1 - 0.053 14.1 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EON33708.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EON33708.1 - 0.056 12.8 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EON33708.1 - 0.06 13.3 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 EON33708.1 - 0.068 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EON33708.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 EON33708.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EON33708.1 - 0.083 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Dynamin family FeoB_N PF02421.18 EON33708.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF2813 PF11398.8 EON33708.1 - 0.17 11.1 0.0 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Transpeptidase PF00905.22 EON33709.1 - 3.9e-39 134.7 0.0 5.7e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain MecA_N PF05223.11 EON33709.1 - 1.8e-14 54.0 0.0 2.9e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain DUF4081 PF13312.6 EON33710.1 - 4e-36 123.4 0.1 1.1e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4081) FR47 PF08445.10 EON33710.1 - 1.9e-11 43.8 0.1 3.6e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EON33710.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON33710.1 - 0.00049 20.0 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON33710.1 - 0.013 15.9 0.2 0.042 14.3 0.2 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GcpE PF04551.14 EON33711.1 - 7.7e-133 442.9 0.0 9.6e-133 442.6 0.0 1.0 1 0 0 1 1 1 1 GcpE protein zf-RING_7 PF02591.15 EON33711.1 - 0.093 12.9 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain Peptidase_M50 PF02163.22 EON33712.1 - 1e-51 175.7 0.0 1.3e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 EON33712.1 - 1.6e-07 31.0 0.2 3.7e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EON33712.1 - 7.8e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EON33712.1 - 0.00017 21.9 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EON33712.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_M50B PF13398.6 EON33712.1 - 0.0053 16.4 0.4 0.058 13.0 0.4 2.3 2 0 0 2 2 2 1 Peptidase M50B-like DXP_redisom_C PF08436.12 EON33713.1 - 6.3e-38 128.8 0.0 1.3e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 EON33713.1 - 4.5e-34 117.9 0.7 7.6e-34 117.2 0.7 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 EON33713.1 - 6.6e-33 113.4 0.0 1.1e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Calici_MSP PF05752.11 EON33713.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein ADH_zinc_N PF00107.26 EON33713.1 - 0.21 11.6 1.4 0.49 10.4 0.5 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF2631 PF10939.8 EON33714.1 - 3.6e-23 81.2 0.5 5.4e-23 80.6 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2631) DUF4181 PF13789.6 EON33714.1 - 0.04 14.2 1.1 0.051 13.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Radical_SAM PF04055.21 EON33715.1 - 2.4e-23 83.3 0.0 4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EON33715.1 - 0.038 14.1 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain LapA_dom PF06305.11 EON33716.1 - 3e-10 39.8 2.3 3e-10 39.8 2.3 2.1 1 1 1 2 2 2 1 Lipopolysaccharide assembly protein A domain CrgA PF06781.12 EON33716.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Cell division protein CrgA 7tm_7 PF08395.12 EON33716.1 - 0.039 13.2 0.1 0.043 13.0 0.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF3592 PF12158.8 EON33716.1 - 0.32 11.0 2.1 0.9 9.6 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DUF202 PF02656.15 EON33716.1 - 0.34 11.4 4.1 0.58 10.6 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Insulin_TMD PF17870.1 EON33716.1 - 0.41 10.7 0.2 0.41 10.7 0.2 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Phage_holin_3_6 PF07332.11 EON33716.1 - 1.5 8.9 10.6 2.4 8.3 10.6 1.3 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CTP_transf_1 PF01148.20 EON33717.1 - 5.5e-56 190.3 20.0 6.6e-56 190.0 20.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family RRF PF01765.19 EON33718.1 - 5.1e-60 202.1 2.3 7.3e-60 201.6 2.3 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.13 EON33718.1 - 0.0053 17.3 4.1 0.0053 17.3 4.1 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Metal_resist PF13801.6 EON33718.1 - 0.0077 16.4 0.4 0.013 15.7 0.4 1.4 1 0 0 1 1 1 1 Heavy-metal resistance DUF1542 PF07564.11 EON33718.1 - 0.55 10.4 9.4 0.42 10.8 2.2 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) YtxH PF12732.7 EON33718.1 - 6.1 7.5 7.2 26 5.4 5.6 2.4 2 1 0 2 2 2 0 YtxH-like protein AA_kinase PF00696.28 EON33719.1 - 2e-32 112.8 0.1 2.3e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family NYAP_C PF15452.6 EON33719.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Esterase PF00756.20 EON33720.1 - 7.1e-37 127.4 0.0 1e-36 126.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Condensation PF00668.20 EON33721.1 - 4.3e-23 81.7 0.0 9.5e-23 80.6 0.0 1.4 2 0 0 2 2 2 1 Condensation domain Aim19 PF10315.9 EON33721.1 - 0.032 14.5 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 MFS_1 PF07690.16 EON33722.1 - 1.1e-22 80.5 43.3 1.1e-22 80.5 43.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.15 EON33722.1 - 0.22 10.5 32.0 0.04 12.9 4.7 2.9 3 0 0 3 3 3 0 PUCC protein DUF2070 PF09843.9 EON33722.1 - 2.9 6.1 8.6 0.33 9.2 4.3 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) EF_TS PF00889.19 EON33723.1 - 4.4e-63 212.6 0.1 5.7e-63 212.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor TS DUF348 PF03990.14 EON33723.1 - 0.036 13.8 2.0 0.33 10.7 0.1 2.6 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain DUF4575 PF15143.6 EON33723.1 - 0.069 13.4 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) SWIRM-assoc_3 PF16498.5 EON33723.1 - 0.13 12.5 3.4 0.14 12.4 0.4 2.5 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal Ribosomal_S2 PF00318.20 EON33724.1 - 9.2e-98 325.7 0.0 1.1e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 PucR PF07905.11 EON33724.1 - 0.076 13.3 0.0 4 7.7 0.0 2.3 1 1 1 2 2 2 0 Purine catabolism regulatory protein-like family Peptidase_M23 PF01551.22 EON33725.1 - 3.8e-14 52.7 0.1 5e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M23 Phage_integrase PF00589.22 EON33726.1 - 1.8e-42 145.1 0.0 3.1e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EON33726.1 - 3.8e-17 62.3 0.3 1.1e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EON33726.1 - 2.8e-05 24.4 0.0 0.00013 22.3 0.0 1.9 1 1 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EON33726.1 - 0.00044 20.7 0.0 0.00077 19.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain HTH_Tnp_ISL3 PF13542.6 EON33726.1 - 2.7 7.5 6.4 2.3 7.7 0.7 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 SIP PF04954.13 EON33727.1 - 1e-35 122.8 0.7 1.5e-35 122.3 0.7 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 EON33727.1 - 3.7e-29 101.4 0.0 8.5e-29 100.2 0.0 1.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain TetR_N PF00440.23 EON33728.1 - 1.5e-09 37.5 0.1 3.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 EON33728.1 - 0.033 14.2 3.6 0.34 11.0 0.6 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain TetR_C_31 PF17940.1 EON33728.1 - 0.058 13.6 8.0 0.023 14.9 4.8 1.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DNA_processg_A PF02481.15 EON33729.1 - 5.9e-65 218.4 2.3 5.9e-65 218.4 2.3 1.4 2 0 0 2 2 2 1 DNA recombination-mediator protein A DprA_WH PF17782.1 EON33729.1 - 3.5e-06 27.0 0.3 1.9e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 DprA winged helix domain LDcluster4 PF18306.1 EON33729.1 - 0.013 15.1 6.3 0.08 12.5 6.5 2.1 2 1 0 2 2 2 0 SLOG cluster4 family Cytochrom_B558a PF05038.13 EON33729.1 - 0.059 12.9 1.2 0.11 12.1 1.2 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Mg_chelatase PF01078.21 EON33730.1 - 2.5e-26 92.4 0.0 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 EON33730.1 - 2.1e-23 82.7 0.1 2.9e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal Resolvase PF00239.21 EON33731.1 - 2.8e-20 72.9 2.4 3.1e-20 72.8 0.9 1.8 2 0 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 EON33731.1 - 4e-13 49.7 0.3 3.6e-12 46.6 0.0 2.6 3 1 0 3 3 3 1 Recombinase Zn_ribbon_recom PF13408.6 EON33731.1 - 9.6e-08 32.4 0.2 1.9e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain GrpE PF01025.19 EON33731.1 - 0.0071 16.0 0.1 0.39 10.3 0.3 2.2 2 0 0 2 2 2 1 GrpE T_hemolysin PF12261.8 EON33731.1 - 0.053 13.3 0.0 0.28 10.9 0.0 2.0 1 1 1 2 2 2 0 Thermostable hemolysin Amidohydro_2 PF04909.14 EON33732.1 - 0.036 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Lsr2 PF11774.8 EON33733.1 - 6e-35 119.7 0.3 6.6e-35 119.6 0.3 1.0 1 0 0 1 1 1 1 Lsr2 RseC_MucC PF04246.12 EON33734.1 - 0.022 14.7 0.4 0.023 14.6 0.4 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC bacHORMA_1 PF18138.1 EON33735.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain family 1 PLDc_N PF13396.6 EON33736.1 - 0.005 16.7 0.4 0.0078 16.1 0.4 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal CRA PF06589.11 EON33736.1 - 0.018 15.1 0.2 0.02 15.0 0.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) LRRFIP PF09738.9 EON33736.1 - 0.018 14.5 2.0 0.023 14.2 2.0 1.1 1 0 0 1 1 1 0 LRRFIP family Yuri_gagarin PF15934.5 EON33736.1 - 0.052 13.4 0.6 0.089 12.6 0.6 1.4 1 1 0 1 1 1 0 Yuri gagarin PhoU PF01895.19 EON33736.1 - 0.11 12.9 1.1 0.41 11.2 0.1 1.9 1 1 1 2 2 2 0 PhoU domain Prophage_tail PF06605.11 EON33738.1 - 0.0019 17.5 0.3 0.0052 16.1 0.3 1.7 1 1 0 1 1 1 1 Prophage endopeptidase tail Sipho_tail PF05709.11 EON33739.1 - 2e-16 60.2 0.0 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Phage tail protein PhageMin_Tail PF10145.9 EON33740.1 - 0.0045 16.9 1.8 0.017 15.0 1.8 2.0 1 1 0 1 1 1 1 Phage-related minor tail protein DUF4244 PF14029.6 EON33740.1 - 0.53 9.8 3.5 1.6 8.2 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) TMP_2 PF06791.13 EON33740.1 - 2.5 7.7 11.5 0.04 13.6 1.6 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein MG2 PF01835.19 EON33743.1 - 0.17 12.4 1.3 13 6.4 0.0 2.9 3 0 0 3 3 3 0 MG2 domain Tom37 PF10568.9 EON33746.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Phage_tail_S PF05069.13 EON33747.1 - 0.0044 16.9 0.2 0.008 16.0 0.2 1.5 1 1 0 1 1 1 1 Phage virion morphogenesis family DUF1320 PF07030.12 EON33748.1 - 4.6e-05 23.5 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1320) Pectate_lyase_3 PF12708.7 EON33749.1 - 8.4e-20 71.5 11.2 8.4e-20 71.5 11.2 2.8 2 1 1 3 3 3 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 EON33749.1 - 0.0021 17.7 0.2 0.028 14.1 0.2 2.6 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 EON33749.1 - 0.042 13.7 4.6 0.13 12.1 3.2 2.4 1 1 1 2 2 2 0 Right handed beta helix region DUF4957 PF16318.5 EON33749.1 - 0.58 10.1 5.8 3.1 7.7 2.6 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4957) DUF2207 PF09972.9 EON33750.1 - 0.056 12.2 0.3 0.064 12.0 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 EON33750.1 - 0.068 12.3 0.3 0.076 12.1 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GspL_C PF12693.7 EON33750.1 - 0.097 12.5 2.2 0.088 12.6 1.6 1.3 1 1 0 1 1 1 0 GspL periplasmic domain Mrr_cat PF04471.12 EON33751.1 - 1.3e-10 41.3 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF2156 PF09924.9 EON33751.1 - 0.03 13.3 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) ATP-synt_B PF00430.18 EON33752.1 - 0.021 14.9 23.2 0.067 13.3 23.2 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DivIVA PF05103.13 EON33752.1 - 0.27 11.3 19.7 0.26 11.4 11.8 2.1 1 1 1 2 2 2 0 DivIVA protein DUF883 PF05957.13 EON33752.1 - 0.67 10.6 12.6 0.27 11.9 8.4 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.8 EON33752.1 - 0.9 8.7 16.3 0.46 9.7 14.5 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein V-ATPase_G_2 PF16999.5 EON33752.1 - 1.9 9.0 23.3 0.66 10.4 7.1 2.7 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit SOAR PF16533.5 EON33752.1 - 6.4 6.8 9.9 13 5.8 2.6 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF3042 PF11240.8 EON33753.1 - 6.5 6.9 9.7 0.28 11.2 0.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3042) Phage_cap_E PF03864.15 EON33754.1 - 1.6e-06 27.6 0.3 4.7e-05 22.7 0.1 2.1 1 1 0 2 2 2 2 Phage major capsid protein E DUF2190 PF09956.9 EON33755.1 - 6.6e-10 39.4 9.1 7.9e-10 39.1 9.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2190) Staphostatin_B PF09023.10 EON33755.1 - 0.033 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Staphostatin B Big_6 PF17936.1 EON33755.1 - 0.09 13.1 7.9 0.14 12.4 7.7 1.4 1 1 0 1 1 1 0 Bacterial Ig domain DUF1918 PF08940.11 EON33755.1 - 0.099 12.3 0.0 0.86 9.3 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1918) Mu-like_Pro PF10123.9 EON33756.1 - 2.4e-19 70.1 11.2 3.7e-19 69.5 10.7 1.6 1 1 0 1 1 1 1 Mu-like prophage I protein DUF4994 PF16385.5 EON33756.1 - 0.45 10.5 2.6 0.36 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF1940 PF09155.10 EON33756.1 - 0.63 10.1 2.3 1.1 9.4 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) TetR_N PF00440.23 EON33757.1 - 0.1 12.4 0.1 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Phage_Mu_F PF04233.14 EON33758.1 - 1.6e-12 48.1 0.1 3.2e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Phage Mu protein F like protein Phage_min_cap2 PF06152.11 EON33758.1 - 0.012 14.6 0.5 0.013 14.5 0.5 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 ESAG1 PF03238.13 EON33758.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 ESAG protein DUF935 PF06074.12 EON33759.1 - 9e-15 54.4 6.9 1.1e-14 54.0 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF935) 2_5_RNA_ligase2 PF13563.6 EON33759.1 - 4.7e-09 36.3 0.0 9.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EON33759.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase IlvC PF01450.19 EON33759.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Terminase_6 PF03237.15 EON33760.1 - 0.00041 20.1 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Terminase-like family AAA_25 PF13481.6 EON33760.1 - 0.037 13.6 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EON33760.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 EON33760.1 - 0.091 13.0 0.3 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EON33760.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein N6_N4_Mtase PF01555.18 EON33762.1 - 1.6e-41 142.5 0.0 9e-41 140.1 0.0 2.0 1 1 0 1 1 1 1 DNA methylase UPF0020 PF01170.18 EON33762.1 - 0.043 13.5 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EON33762.1 - 0.058 13.0 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 ResIII PF04851.15 EON33763.1 - 9.4e-06 25.7 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EON33763.1 - 0.035 14.5 0.2 0.089 13.2 0.2 1.7 1 0 0 1 1 1 0 AAA ATPase domain Bac_DnaA PF00308.18 EON33764.1 - 2.4e-16 60.2 0.5 6.7e-12 45.7 0.1 2.0 1 1 0 2 2 2 2 Bacterial dnaA protein IstB_IS21 PF01695.17 EON33764.1 - 0.00072 19.3 0.7 0.8 9.4 0.1 2.1 1 1 1 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 EON33764.1 - 0.00094 19.6 0.3 0.0024 18.3 0.3 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EON33764.1 - 0.0075 16.5 3.1 1.5 9.1 0.2 2.1 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.22 EON33764.1 - 0.018 15.4 0.1 0.042 14.3 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA PF00004.29 EON33764.1 - 0.025 15.0 0.8 0.13 12.7 0.8 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EON33764.1 - 0.034 14.7 1.0 0.11 13.0 1.0 1.8 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EON33764.1 - 0.043 13.7 2.4 0.51 10.2 0.2 2.1 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 EON33764.1 - 0.086 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain MPTase-PolyVal PF18818.1 EON33768.1 - 0.0073 16.4 0.2 0.013 15.6 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF4157 PF13699.6 EON33768.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) AP2 PF00847.20 EON33769.1 - 4.5e-06 26.8 5.9 4.9e-06 26.7 0.7 2.6 3 0 0 3 3 3 1 AP2 domain DUF4131 PF13567.6 EON33771.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mrr_cat PF04471.12 EON33773.1 - 1e-15 57.8 0.0 1.7e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF2034 PF10356.9 EON33773.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DUF1543 PF07566.12 EON33774.1 - 0.012 15.3 2.1 0.089 12.5 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) DUF4942 PF13708.6 EON33779.1 - 5.2e-40 137.6 1.1 8.7e-40 136.8 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4942) MTS PF05175.14 EON33779.1 - 0.0017 18.0 0.0 0.01 15.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Dam PF05869.11 EON33779.1 - 0.0053 16.3 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RrnaAD PF00398.20 EON33779.1 - 0.044 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF4606 PF15379.6 EON33779.1 - 0.094 13.0 1.4 0.17 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) PBECR5 PF18814.1 EON33779.1 - 0.15 11.9 1.3 0.26 11.2 1.3 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Replic_Relax PF13814.6 EON33780.1 - 1.1e-14 54.9 0.0 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation Lactococcin PF04369.13 EON33780.1 - 0.034 14.3 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Lactococcin-like family DUF4726 PF15855.5 EON33782.1 - 0.29 11.4 4.2 0.19 12.0 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4726) Linker_histone PF00538.19 EON33782.1 - 0.69 10.3 3.0 0.5 10.8 0.4 2.2 3 0 0 3 3 3 0 linker histone H1 and H5 family DUF3043 PF11241.8 EON33782.1 - 3.2 7.8 8.5 0.39 10.7 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Sigma70_r4_2 PF08281.12 EON33783.1 - 0.051 13.3 0.3 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 SNCAIP_SNCA_bd PF16700.5 EON33783.1 - 0.075 12.8 0.6 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain PTPA PF03095.15 EON33783.1 - 0.094 12.1 0.1 0.1 12.0 0.1 1.0 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein HTH_50 PF18024.1 EON33783.1 - 0.097 12.3 0.2 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain FpoO PF10621.9 EON33783.1 - 0.13 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Resolvase PF00239.21 EON33786.1 - 2.7e-31 108.6 2.5 3.8e-31 108.2 2.5 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Queuosine_synth PF02547.15 EON33786.1 - 0.012 14.8 0.3 0.33 10.0 0.0 2.0 1 1 0 2 2 2 0 Queuosine biosynthesis protein tRNA-synt_1e PF01406.19 EON33786.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain HTH_28 PF13518.6 EON33786.1 - 0.04 14.0 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 EON33786.1 - 0.059 13.0 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 InsA C-terminal domain HTH_7 PF02796.15 EON33786.1 - 0.067 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TerD PF02342.18 EON33787.1 - 1.6e-58 197.2 0.8 1.8e-58 197.1 0.8 1.0 1 0 0 1 1 1 1 TerD domain DUF1416 PF07210.12 EON33787.1 - 0.049 13.5 0.2 0.36 10.7 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1416) DUF475 PF04332.15 EON33788.1 - 1.1e-113 380.0 12.4 1.5e-113 379.5 12.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF475) TerC PF03741.16 EON33788.1 - 2e-18 66.7 16.0 2.1e-16 60.1 16.0 2.7 1 1 0 1 1 1 1 Integral membrane protein TerC family DUF1330 PF07045.11 EON33788.1 - 0.043 14.2 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Bap31 PF05529.12 EON33788.1 - 3.2 7.6 5.5 6.9 6.5 4.7 2.1 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region Cutinase PF01083.22 EON33791.1 - 3.8e-16 59.6 0.5 7.5e-16 58.6 0.5 1.6 1 1 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EON33791.1 - 0.00083 19.0 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Hydrolase_4 PF12146.8 EON33791.1 - 0.058 12.7 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EON33791.1 - 0.073 12.9 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 EON33791.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.11 EON33791.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DnaJ PF00226.31 EON33793.1 - 7.1e-09 35.7 0.1 1.2e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Chol_subst-bind PF09129.11 EON33793.1 - 0.05 12.6 0.1 0.064 12.2 0.1 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding HNH PF01844.23 EON33795.1 - 0.015 15.5 6.3 0.035 14.3 1.2 2.6 2 1 0 2 2 2 0 HNH endonuclease NinG PF05766.12 EON33795.1 - 0.015 15.2 4.4 0.1 12.5 0.7 2.0 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein DUF3846 PF12957.7 EON33796.1 - 1.1e-13 51.2 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) Attacin_C PF03769.15 EON33796.1 - 0.044 14.0 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 Attacin, C-terminal region Ten1 PF12658.7 EON33797.1 - 0.023 14.6 0.2 0.032 14.2 0.2 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit DUF2514 PF10721.9 EON33799.1 - 0.025 14.6 1.8 0.029 14.4 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Spc7 PF08317.11 EON33799.1 - 0.096 11.5 0.2 0.095 11.6 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec34 PF04136.15 EON33799.1 - 0.14 12.0 0.1 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 Sec34-like family DUF87 PF01935.17 EON33800.1 - 5.8e-09 36.4 0.0 1.6e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 EON33800.1 - 1.7e-08 33.8 0.6 4.6e-05 22.5 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 EON33800.1 - 0.00096 19.2 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.7 EON33800.1 - 0.0012 17.9 0.0 0.061 12.2 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.6 EON33800.1 - 0.0015 18.8 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON33800.1 - 0.0029 18.0 0.1 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TraG-D_C PF12696.7 EON33800.1 - 0.0033 17.4 0.2 0.0079 16.2 0.1 1.6 2 0 0 2 2 1 1 TraM recognition site of TraD and TraG DEAD PF00270.29 EON33800.1 - 0.0035 17.1 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EON33800.1 - 0.0053 16.8 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF853 PF05872.12 EON33800.1 - 0.0085 14.7 0.4 0.045 12.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) RuvB_N PF05496.12 EON33800.1 - 0.059 13.1 0.3 1.1 9.0 0.1 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EON33800.1 - 0.085 12.1 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 EON33800.1 - 0.12 12.1 0.3 0.41 10.3 0.1 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 EON33800.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EON33800.1 - 0.15 11.5 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Coq4 PF05019.13 EON33801.1 - 0.047 13.0 0.2 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF3487 PF11990.8 EON33802.1 - 0.0035 17.2 1.6 0.0043 16.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3487) DUF417 PF04224.12 EON33802.1 - 0.015 14.9 4.2 0.017 14.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF3784 PF12650.7 EON33802.1 - 0.15 12.3 2.7 0.18 12.1 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) SID-1_RNA_chan PF13965.6 EON33802.1 - 0.25 9.7 0.1 0.27 9.6 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gram_pos_anchor PF00746.21 EON33802.1 - 6.4 6.8 7.6 2.4 8.2 0.4 2.8 2 1 0 2 2 2 0 LPXTG cell wall anchor motif DUF2681 PF10883.8 EON33803.1 - 0.0014 18.9 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) DUF2214 PF09980.9 EON33804.1 - 0.068 13.0 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) SpoIIIAH PF12685.7 EON33804.1 - 0.094 12.5 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein RdRP_5 PF07925.11 EON33805.1 - 0.18 9.2 0.0 0.22 8.9 0.0 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 RHH_1 PF01402.21 EON33806.1 - 2.3e-05 24.2 0.6 2.3e-05 24.2 0.6 2.0 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family CT_C_D PF02682.16 EON33806.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D SUV3_C PF12513.8 EON33806.1 - 0.45 10.5 2.0 3.7 7.6 0.1 2.5 1 1 2 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_Sgs1 PF11408.8 EON33807.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Sgs1 RecQ helicase Mg_chelatase PF01078.21 EON33808.1 - 6.7e-46 156.3 0.9 1.1e-45 155.6 0.9 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 EON33808.1 - 1.5e-43 147.5 0.0 2.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 EON33808.1 - 8.9e-06 25.4 0.2 1.2e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Sigma54_activat PF00158.26 EON33808.1 - 1.1e-05 25.2 0.1 0.11 12.2 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain RuvB_N PF05496.12 EON33808.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EON33808.1 - 0.0039 17.3 0.0 0.17 12.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EON33808.1 - 0.0069 16.8 0.1 0.015 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EON33808.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EON33808.1 - 0.023 14.6 0.1 0.062 13.2 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EON33808.1 - 0.029 14.8 0.0 0.13 12.7 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EON33808.1 - 0.042 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON33808.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 EON33808.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EON33808.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EON33808.1 - 0.18 11.7 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nitroreductase PF00881.24 EON33809.1 - 5.4e-22 78.6 0.0 8.5e-22 78.0 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EON33809.1 - 2.9e-06 27.0 0.2 0.0084 15.7 0.0 2.9 2 1 2 4 4 4 2 Putative TM nitroreductase DUF4185 PF13810.6 EON33810.1 - 2.1e-104 349.1 0.1 2.5e-104 348.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) BNR_2 PF13088.6 EON33810.1 - 0.0014 18.0 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EON33810.1 - 0.088 12.9 0.3 0.45 10.7 0.3 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat UPF0102 PF02021.17 EON33811.1 - 9.4e-28 96.3 0.1 1.2e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 EON33811.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 Nuclease-related domain AHJR-like PF18743.1 EON33811.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like PDDEXK_4 PF14281.6 EON33811.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily PDDEXK_10 PF07788.11 EON33811.1 - 0.13 12.2 0.4 0.71 9.8 0.4 2.0 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF992 PF06186.11 EON33811.1 - 0.21 11.4 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF992) DUF2469 PF10611.9 EON33812.1 - 1.4e-52 176.4 3.6 1.6e-52 176.2 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) RNase_HII PF01351.18 EON33813.1 - 4.5e-40 137.6 0.0 5.2e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Peptidase_S24 PF00717.23 EON33814.1 - 2.2e-10 40.4 0.1 7.9e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 EON33814.1 - 1.3e-06 28.3 0.0 0.028 14.2 0.0 2.6 2 2 0 2 2 2 2 Signal peptidase, peptidase S26 zf-DNL PF05180.12 EON33814.1 - 0.062 13.2 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 DNL zinc finger Ribosomal_L19 PF01245.20 EON33815.1 - 4.4e-50 168.3 0.3 4.8e-50 168.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 FxsA PF04186.13 EON33817.1 - 0.0093 16.1 0.3 0.013 15.6 0.3 1.2 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein YbaB_DNA_bd PF02575.16 EON33818.1 - 1.6e-08 34.7 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF3022 PF11226.8 EON33818.1 - 0.012 16.0 2.8 0.11 13.0 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3022) DUF4824 PF16106.5 EON33818.1 - 0.11 11.8 1.2 0.13 11.6 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) tRNA_m1G_MT PF01746.21 EON33819.1 - 6.6e-67 225.0 0.0 7.5e-67 224.8 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RimM PF01782.18 EON33820.1 - 9.8e-22 77.0 0.1 2e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 EON33820.1 - 7.7e-10 38.7 0.1 1.5e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 PRC-barrel domain KH_4 PF13083.6 EON33821.1 - 9.4e-20 70.3 0.1 1.1e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 EON33821.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 KH domain KH_5 PF13184.6 EON33821.1 - 0.079 13.1 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 NusA-like KH domain Ribosomal_S16 PF00886.19 EON33822.1 - 5.5e-23 80.8 0.2 8.4e-23 80.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 ETF_alpha PF00766.19 EON33823.1 - 0.05 13.6 0.1 0.061 13.4 0.1 1.1 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Amidohydro_1 PF01979.20 EON33824.1 - 6.4e-14 52.0 3.2 2.7e-12 46.7 3.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EON33824.1 - 1.5e-05 24.7 10.8 0.0031 17.0 6.5 2.7 2 1 0 2 2 2 2 Amidohydrolase family SRP54 PF00448.22 EON33825.1 - 4.2e-68 228.8 0.0 7e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EON33825.1 - 7.3e-31 106.7 0.7 1.9e-30 105.4 0.7 1.8 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 EON33825.1 - 4.9e-20 71.5 0.3 1.2e-19 70.3 0.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EON33825.1 - 3.9e-05 23.7 0.0 0.00014 21.9 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EON33825.1 - 4.9e-05 23.0 2.1 0.00042 20.0 2.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EON33825.1 - 0.00017 21.4 0.1 0.0011 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON33825.1 - 0.00054 20.3 0.0 0.0026 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EON33825.1 - 0.00092 18.3 0.8 0.00092 18.3 0.8 1.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 EON33825.1 - 0.0015 18.4 0.1 0.15 12.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EON33825.1 - 0.0016 18.4 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase ArsA_ATPase PF02374.15 EON33825.1 - 0.0018 17.5 1.7 0.085 12.0 0.0 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase Zeta_toxin PF06414.12 EON33825.1 - 0.0032 16.8 0.0 0.0066 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.15 EON33825.1 - 0.0056 16.6 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 1 NTPase SRPRB PF09439.10 EON33825.1 - 0.014 14.8 0.1 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 EON33825.1 - 0.019 14.7 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 EON33825.1 - 0.025 14.6 1.8 0.48 10.5 0.8 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EON33825.1 - 0.029 14.5 0.1 0.063 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON33825.1 - 0.061 13.0 1.9 0.11 12.2 0.8 2.0 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 EON33825.1 - 0.064 13.8 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EON33825.1 - 0.073 13.5 1.0 0.16 12.4 0.1 2.1 2 2 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 EON33825.1 - 0.082 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_25 PF13481.6 EON33825.1 - 0.11 12.1 5.3 4 7.0 2.2 3.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 EON33825.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 EON33825.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TsaE PF02367.17 EON33825.1 - 0.23 11.4 0.3 0.71 9.9 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HD PF01966.22 EON33826.1 - 8.1e-11 42.2 0.1 1.9e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 HD domain ACT PF01842.25 EON33826.1 - 5.6e-09 35.6 0.3 0.00014 21.5 0.1 3.0 2 0 0 2 2 2 2 ACT domain GlnD_UR_UTase PF08335.11 EON33826.1 - 1.1e-06 28.9 0.4 9.9e-05 22.5 0.1 2.5 1 1 1 2 2 2 1 GlnD PII-uridylyltransferase ACT_4 PF13291.6 EON33826.1 - 0.00021 21.8 0.0 0.15 12.7 0.0 2.9 3 0 0 3 3 3 2 ACT domain NTP_transf_2 PF01909.23 EON33826.1 - 0.00045 20.4 0.0 0.00092 19.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain GlnE PF03710.15 EON33826.1 - 0.0019 17.6 0.0 0.0059 16.0 0.0 1.8 2 0 0 2 2 2 1 Glutamate-ammonia ligase adenylyltransferase ACT_6 PF13740.6 EON33826.1 - 0.0047 16.9 0.4 3.4 7.7 0.1 3.4 3 0 0 3 3 3 1 ACT domain DUF294 PF03445.13 EON33826.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 P-II PF00543.22 EON33827.1 - 3.6e-42 143.1 2.8 4.1e-42 142.9 2.8 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 EON33827.1 - 0.047 13.8 0.2 0.077 13.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) Ammonium_transp PF00909.21 EON33828.1 - 1.1e-114 383.3 36.8 1.3e-114 383.1 36.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family SRP54 PF00448.22 EON33829.1 - 7.5e-73 244.4 1.9 9.9e-73 244.0 1.9 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EON33829.1 - 2.4e-07 30.9 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EON33829.1 - 2.4e-06 27.4 2.1 4.3e-06 26.6 2.1 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EON33829.1 - 4.2e-06 26.8 0.0 1.2e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EON33829.1 - 6.9e-06 26.5 0.2 1.3e-05 25.7 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EON33829.1 - 0.00046 19.3 0.3 0.00046 19.3 0.3 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EON33829.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EON33829.1 - 0.007 16.7 0.5 0.012 16.0 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EON33829.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EON33829.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase EphA2_TM PF14575.6 EON33829.1 - 0.026 15.4 0.0 0.044 14.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AAA_33 PF13671.6 EON33829.1 - 0.03 14.5 0.2 0.069 13.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_31 PF13614.6 EON33829.1 - 0.034 14.1 0.5 0.074 13.0 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON33829.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EON33829.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EON33829.1 - 0.24 11.1 0.1 0.38 10.4 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase SKG6 PF08693.10 EON33829.1 - 0.27 10.7 8.9 0.64 9.5 8.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2075 PF09848.9 EON33829.1 - 0.27 10.4 0.1 0.36 10.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Adeno_E3_CR2 PF02439.15 EON33829.1 - 0.3 10.9 6.1 0.64 9.8 6.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MobB PF03205.14 EON33829.1 - 0.63 9.9 3.2 0.54 10.1 0.5 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EON33829.1 - 4.8 6.7 5.8 45 3.6 5.8 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EON33830.1 - 4.5e-72 242.1 0.0 5.3e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON33830.1 - 5.8e-19 69.0 0.0 7.3e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 EON33830.1 - 2.2e-18 66.6 0.0 9.8e-18 64.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EON33830.1 - 9.7e-18 65.4 9.8 6e-17 62.8 0.0 3.9 3 1 0 4 4 4 1 AAA domain AAA_15 PF13175.6 EON33830.1 - 9.2e-13 48.6 0.0 7.7e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EON33830.1 - 4.5e-06 26.3 0.1 1.1e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EON33830.1 - 0.0022 18.5 0.8 0.38 11.3 0.1 3.7 3 0 0 3 3 3 1 ABC transporter AAA_22 PF13401.6 EON33830.1 - 0.0079 16.5 1.3 4 7.7 0.0 4.0 4 0 0 4 4 4 1 AAA domain F_actin_bind PF08919.10 EON33830.1 - 0.33 11.1 3.5 0.44 10.7 0.1 3.0 3 0 0 3 3 2 0 F-actin binding Baculo_PEP_C PF04513.12 EON33830.1 - 0.55 10.3 17.7 1.8 8.6 0.7 5.6 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus E2F_CC-MB PF16421.5 EON33830.1 - 3.8 7.9 4.8 3.6 8.0 0.0 3.2 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain Acylphosphatase PF00708.18 EON33831.1 - 4.1e-21 75.2 0.0 5.1e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase DUF1495 PF07381.11 EON33831.1 - 0.19 11.5 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) OsmC PF02566.19 EON33832.1 - 2.2e-10 40.9 0.0 6e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 OsmC-like protein YaaC PF14175.6 EON33833.1 - 9.5e-51 172.9 0.0 1.3e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 YaaC-like Protein Polbeta PF18765.1 EON33834.1 - 0.0004 20.4 0.0 0.00044 20.3 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 EON33834.1 - 0.0027 17.9 0.0 0.0036 17.6 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyltransferase domain MdcG PF10620.9 EON33834.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.4 1 1 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG APH PF01636.23 EON33836.1 - 0.0097 15.8 2.5 0.24 11.3 0.0 2.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family RRM_1 PF00076.22 EON33836.1 - 0.038 13.8 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.13 EON33836.1 - 0.11 12.9 0.2 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 Sporulation related domain Fapy_DNA_glyco PF01149.24 EON33837.1 - 3.4e-35 121.2 0.6 8e-35 120.0 0.1 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EON33837.1 - 5.5e-27 93.6 0.0 8.2e-27 93.0 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 EON33837.1 - 1.4e-09 37.6 4.4 3e-09 36.6 4.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FbpA PF05833.11 EON33837.1 - 0.0029 16.5 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Auto_anti-p27 PF06677.12 EON33837.1 - 0.013 15.6 0.8 0.027 14.6 0.8 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Tautomerase PF01361.21 EON33837.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme TackOD1 PF18551.1 EON33837.1 - 0.051 13.2 0.4 0.08 12.6 0.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-MYND PF01753.18 EON33837.1 - 0.42 10.8 3.3 0.73 10.0 3.3 1.4 1 0 0 1 1 1 0 MYND finger Ribonucleas_3_3 PF14622.6 EON33838.1 - 2.1e-34 118.5 0.0 2.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EON33838.1 - 6.8e-19 68.4 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EON33838.1 - 1.9e-16 60.5 0.0 2.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EON33838.1 - 0.00083 19.6 0.1 0.0034 17.6 0.1 1.8 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 YceD PF02620.17 EON33839.1 - 3.2e-29 101.5 0.5 5e-29 100.9 0.5 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD V-ATPase_G_2 PF16999.5 EON33840.1 - 4.3e-07 30.3 28.8 0.0043 17.5 0.7 3.4 1 1 2 3 3 3 3 Vacuolar (H+)-ATPase G subunit DivIVA PF05103.13 EON33840.1 - 6.9e-07 29.4 20.4 0.00096 19.2 5.3 3.2 1 1 2 3 3 3 3 DivIVA protein ATP-synt_B PF00430.18 EON33840.1 - 9e-07 29.0 27.4 0.00022 21.3 12.5 3.2 1 1 2 3 3 3 2 ATP synthase B/B' CF(0) DUF4088 PF13317.6 EON33840.1 - 2.4e-05 24.0 5.9 3.7e-05 23.4 5.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4088) HrpE PF06188.12 EON33840.1 - 0.0018 18.2 16.1 0.61 9.9 8.8 3.1 1 1 2 3 3 3 2 HrpE/YscL/FliH and V-type ATPase subunit E ApoLp-III PF07464.11 EON33840.1 - 0.02 15.0 1.5 0.31 11.1 0.9 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) BAF1_ABF1 PF04684.13 EON33840.1 - 0.067 12.2 5.7 0.066 12.3 5.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor YlqD PF11068.8 EON33840.1 - 0.29 11.5 1.5 3.4 8.1 0.1 2.2 1 1 1 2 2 2 0 YlqD protein Phasin PF05597.11 EON33840.1 - 2.3 8.3 10.8 7.1 6.6 0.8 3.2 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) vATP-synt_E PF01991.18 EON33840.1 - 3.7 6.9 18.7 2.4 7.5 6.6 2.9 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Apolipoprotein PF01442.18 EON33840.1 - 4.5 7.1 19.9 12 5.7 19.8 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CTP_transf_like PF01467.26 EON33841.1 - 8.2e-14 52.0 0.0 9.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 EON33841.1 - 2.3e-09 37.2 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain Cons_hypoth95 PF03602.15 EON33842.1 - 1.2e-44 152.1 0.0 1.4e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EON33842.1 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EON33842.1 - 0.007 17.4 0.1 0.0099 16.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON33842.1 - 0.077 12.4 0.1 0.089 12.2 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Acetyltransf_1 PF00583.25 EON33843.1 - 7.3e-12 45.6 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON33843.1 - 1.2e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON33843.1 - 1.7e-05 24.9 0.1 2.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 EON33843.1 - 2.8e-05 24.4 0.0 4.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EON33843.1 - 3.1e-05 24.2 0.2 5.1e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EON33843.1 - 0.00054 20.7 0.0 0.00081 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON33843.1 - 0.025 14.6 0.1 0.051 13.7 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON33843.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Aminotran_3 PF00202.21 EON33844.1 - 8.9e-80 268.3 0.0 1.2e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Ectoine_synth PF06339.12 EON33845.1 - 1.8e-54 183.3 0.0 2e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 EON33845.1 - 3.4e-06 26.7 0.3 5e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EON33845.1 - 0.00076 19.2 0.1 0.00088 19.0 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EON33845.1 - 0.0055 16.6 0.1 0.0077 16.1 0.1 1.3 1 1 0 1 1 1 1 AraC-like ligand binding domain Abhydrolase_6 PF12697.7 EON33846.1 - 5.9e-11 43.4 11.8 7.5e-11 43.1 11.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON33846.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON33846.1 - 5.5e-05 22.5 0.0 7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EON33846.1 - 0.0033 16.2 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family PSK_trans_fac PF07704.11 EON33846.1 - 0.012 16.3 1.2 0.012 16.3 1.2 2.7 3 1 1 4 4 4 0 Rv0623-like transcription factor TetR_N PF00440.23 EON33847.1 - 6.7e-12 45.0 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family SIR2 PF02146.17 EON33848.1 - 4.7e-41 140.6 0.0 8e-41 139.9 0.0 1.4 1 1 0 1 1 1 1 Sir2 family zf_Rg PF17915.1 EON33848.1 - 0.1 12.0 1.5 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Reverse gyrase zinc finger zf-ribbon_3 PF13248.6 EON33848.1 - 0.11 12.0 0.7 0.45 10.0 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TPP_enzyme_M PF00205.22 EON33848.1 - 0.14 11.8 1.4 0.86 9.3 0.1 2.6 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Annexin_like PF18411.1 EON33848.1 - 0.21 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Annexin-like domain AA_kinase PF00696.28 EON33849.1 - 4.6e-37 127.9 3.5 6.1e-37 127.5 3.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EON33849.1 - 7.2e-15 54.7 0.7 2.3e-14 53.1 0.2 2.2 2 0 0 2 2 2 1 PUA domain GTP1_OBG PF01018.22 EON33850.1 - 4.7e-51 172.4 7.4 7.2e-51 171.8 7.4 1.3 1 0 0 1 1 1 1 GTP1/OBG DUF1967 PF09269.11 EON33850.1 - 7.1e-25 86.7 0.0 1.2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) MMR_HSR1 PF01926.23 EON33850.1 - 1.3e-21 76.8 0.0 3.4e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON33850.1 - 4.5e-08 32.8 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EON33850.1 - 0.018 15.0 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 EON33850.1 - 0.029 13.8 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family MeaB PF03308.16 EON33850.1 - 0.032 13.2 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ribosomal_L27 PF01016.19 EON33851.1 - 3.7e-36 123.0 3.6 4.1e-36 122.8 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 EON33852.1 - 3.5e-33 113.9 4.5 4.1e-33 113.7 4.5 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein RNase_E_G PF10150.9 EON33853.1 - 3e-100 335.1 0.0 4e-100 334.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family IF2_N PF04760.15 EON33853.1 - 7.7e-09 35.3 0.0 3.2e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region S1 PF00575.23 EON33853.1 - 0.00019 21.7 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain NDK PF00334.19 EON33854.1 - 5.4e-51 172.2 0.0 6.2e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4233 PF14017.6 EON33856.1 - 3.1e-24 85.3 11.5 3.5e-24 85.1 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4233) Mur_ligase_M PF08245.12 EON33857.1 - 3.1e-15 56.7 0.0 5.7e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EON33857.1 - 5.8e-11 42.5 0.0 1.7e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF2525 PF10733.9 EON33857.1 - 0.079 13.2 0.1 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) tRNA-synt_1 PF00133.22 EON33858.1 - 8.2e-195 648.6 0.0 1.5e-191 637.7 0.0 3.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EON33858.1 - 5e-38 130.4 0.0 8.1e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EON33858.1 - 6.5e-21 74.5 0.1 2.8e-11 42.8 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 EON33858.1 - 9.2e-16 57.9 4.1 1.9e-15 56.9 4.1 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 EON33858.1 - 3.8e-09 36.3 0.1 1.2e-07 31.4 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EON33858.1 - 4.3e-05 23.0 0.0 0.19 11.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EON33858.1 - 0.00014 20.9 0.0 0.00031 19.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (K) NTP_transf_3 PF12804.7 EON33859.1 - 1.5e-35 122.9 4.5 2.1e-35 122.5 4.5 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EON33859.1 - 0.011 15.5 0.4 0.03 14.1 0.4 1.8 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Molybdopterin PF00384.22 EON33860.1 - 1.6e-23 83.3 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EON33860.1 - 2.5e-08 33.9 0.0 6.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_2 PF07724.14 EON33861.1 - 1.9e-50 171.3 0.0 3.7e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 EON33861.1 - 8.6e-21 73.5 6.0 1.9e-20 72.4 6.0 1.6 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 EON33861.1 - 1.6e-17 64.2 0.1 5e-17 62.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EON33861.1 - 2.1e-17 63.0 0.1 6e-17 61.5 0.0 1.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EON33861.1 - 1.3e-07 31.7 0.0 3.1e-06 27.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EON33861.1 - 8e-06 25.4 0.3 0.002 17.5 0.1 3.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EON33861.1 - 2.5e-05 24.1 0.7 0.00015 21.5 0.2 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EON33861.1 - 0.0001 22.6 0.4 0.0013 19.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain MCM PF00493.23 EON33861.1 - 0.00015 20.9 0.1 0.00026 20.2 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_14 PF13173.6 EON33861.1 - 0.0003 20.8 0.2 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EON33861.1 - 0.00041 20.1 0.0 0.034 13.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EON33861.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein B12-binding_2 PF02607.17 EON33861.1 - 0.0025 18.2 0.2 0.013 15.9 0.1 2.3 2 0 0 2 2 1 1 B12 binding domain AAA_18 PF13238.6 EON33861.1 - 0.0033 18.0 0.0 0.0085 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EON33861.1 - 0.0094 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 EON33861.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 EON33861.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 EON33861.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.7 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 EON33861.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EON33861.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 EON33861.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EON33861.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 EON33861.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EON33861.1 - 0.028 14.4 0.0 0.079 12.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EON33861.1 - 0.028 14.8 0.1 0.13 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EON33861.1 - 0.036 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON33861.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 EON33861.1 - 0.064 12.4 0.1 0.13 11.4 0.1 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain SAP30_Sin3_bdg PF13867.6 EON33861.1 - 0.068 13.5 0.0 3.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 AAA_3 PF07726.11 EON33861.1 - 0.13 12.1 1.0 1.6 8.6 0.0 3.2 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EON33861.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CLP_protease PF00574.23 EON33862.1 - 4.1e-74 248.4 0.0 5.1e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease CLP_protease PF00574.23 EON33863.1 - 3.3e-76 255.3 0.0 3.8e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease Trigger_N PF05697.13 EON33864.1 - 7.9e-42 142.9 0.5 7.9e-42 142.9 0.5 2.9 3 1 0 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 EON33864.1 - 1.7e-37 128.9 16.8 3.4e-37 127.9 13.8 2.8 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 EON33864.1 - 3.4e-07 30.5 0.1 1e-06 28.9 0.1 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MRP-S31 PF15433.6 EON33864.1 - 0.0067 16.1 6.5 0.0094 15.7 6.5 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 BAR PF03114.18 EON33864.1 - 0.0089 15.7 3.5 0.015 15.0 3.5 1.3 1 0 0 1 1 1 1 BAR domain ASCH PF04266.14 EON33864.1 - 0.14 12.7 1.1 0.36 11.4 0.1 2.1 2 0 0 2 2 2 0 ASCH domain Phage_TAC_4 PF08748.11 EON33864.1 - 4.1 7.7 8.8 0.59 10.5 0.8 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone YkuD PF03734.14 EON33866.1 - 6.8e-23 81.7 2.5 9e-23 81.3 2.5 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF2778 PF10908.8 EON33866.1 - 0.21 11.9 1.0 0.49 10.7 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2778) PE-PPE PF08237.11 EON33867.1 - 6.4e-12 45.5 0.0 9.1e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Cutinase PF01083.22 EON33867.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.14 EON33867.1 - 0.2 11.1 0.0 0.3 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cupin_2 PF07883.11 EON33868.1 - 0.01 15.6 0.1 0.025 14.3 0.1 1.8 1 1 0 1 1 1 0 Cupin domain Trypan_PARP PF05887.11 EON33868.1 - 0.014 15.4 0.1 0.081 12.9 0.1 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) H2TH PF06831.14 EON33869.1 - 9e-24 83.3 0.0 1.6e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 EON33869.1 - 0.00012 21.8 3.0 0.00025 20.8 3.0 1.6 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS Fapy_DNA_glyco PF01149.24 EON33869.1 - 0.0008 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 EON33869.1 - 0.06 12.1 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) LacAB_rpiB PF02502.18 EON33870.1 - 1.3e-44 151.6 0.0 1.4e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Peptidase_M48 PF01435.18 EON33871.1 - 3.6e-23 82.4 0.0 9.9e-16 58.1 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M48 FA_desaturase PF00487.24 EON33871.1 - 0.48 10.2 4.8 0.72 9.6 0.7 2.4 3 0 0 3 3 3 0 Fatty acid desaturase DSBA PF01323.20 EON33872.1 - 1.6e-10 41.1 2.8 2.7e-09 37.1 2.8 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain TetR_N PF00440.23 EON33873.1 - 8.6e-28 95.9 0.2 7.9e-13 48.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON33873.1 - 1.9e-07 31.3 0.1 0.00088 19.5 0.0 2.7 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain DUF2934 PF11154.8 EON33873.1 - 0.024 14.3 0.8 1.7 8.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2934) HRCT1 PF15758.5 EON33873.1 - 0.16 12.9 0.3 0.46 11.5 0.3 1.7 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 HAD_2 PF13419.6 EON33873.1 - 0.22 11.6 0.0 3.8 7.5 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TetR_C_15 PF17918.1 EON33873.1 - 5.2 7.9 11.4 1.4 9.7 0.7 3.8 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain ERAP1_C PF11838.8 EON33874.1 - 7.1e-59 199.9 1.6 1.2e-58 199.2 1.6 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EON33874.1 - 6e-57 192.7 0.4 9e-57 192.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EON33874.1 - 4.2e-19 69.5 0.0 8.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Response_reg PF00072.24 EON33875.1 - 2.4e-21 76.0 0.0 3.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HTH_IclR PF09339.10 EON33875.1 - 0.0025 17.6 0.1 0.0066 16.2 0.1 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 EON33875.1 - 0.0027 17.6 0.6 0.013 15.4 0.0 2.4 4 0 0 4 4 4 1 HTH domain HTH_24 PF13412.6 EON33875.1 - 0.0059 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EON33875.1 - 0.011 15.7 0.3 0.038 14.0 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 EON33875.1 - 0.012 15.4 0.1 0.012 15.4 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Crp PF00325.20 EON33875.1 - 0.017 14.8 0.1 0.041 13.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 EON33875.1 - 0.021 14.7 0.4 0.11 12.4 0.4 2.2 1 1 0 1 1 1 0 MarR family HTH_22 PF13309.6 EON33875.1 - 0.027 14.6 0.2 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 HTH domain Sigma70_r4_2 PF08281.12 EON33875.1 - 0.05 13.3 0.7 0.91 9.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 TrmB PF01978.19 EON33875.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB sCache_3_2 PF17203.4 EON33876.1 - 2.5e-27 95.7 0.8 6.6e-27 94.4 0.8 1.8 1 0 0 1 1 1 1 Single cache domain 3 HATPase_c PF02518.26 EON33876.1 - 2.4e-10 40.9 0.0 7.6e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EON33876.1 - 1.4e-07 31.4 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 GHKL domain SPOB_a PF14689.6 EON33876.1 - 1.4e-05 24.7 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain HATPase_c_3 PF13589.6 EON33876.1 - 7.7e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 EON33876.1 - 0.00025 20.9 0.0 0.00042 20.2 0.0 1.3 1 0 0 1 1 1 1 Cache domain HATPase_c_2 PF13581.6 EON33876.1 - 0.0034 17.3 0.3 0.026 14.5 0.2 2.5 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 EON33876.1 - 0.023 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain sCache_3_3 PF17202.4 EON33876.1 - 0.036 14.5 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 Single cache domain 3 PAS PF00989.25 EON33876.1 - 0.11 12.4 0.0 0.49 10.4 0.0 2.1 1 1 0 1 1 1 0 PAS fold SDF PF00375.18 EON33877.1 - 1.5e-100 337.0 35.5 1.7e-100 336.8 35.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Syndecan PF01034.20 EON33877.1 - 0.14 12.1 4.9 7.9 6.5 0.0 3.4 2 0 0 2 2 2 0 Syndecan domain DUF5130 PF17174.4 EON33878.1 - 1.7e-58 196.7 0.8 1.9e-58 196.5 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) TPM_phosphatase PF04536.14 EON33878.1 - 0.0005 20.2 0.0 0.00062 19.9 0.0 1.1 1 0 0 1 1 1 1 TPM domain MLIP PF15274.6 EON33878.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Muscular LMNA-interacting protein DUF3592 PF12158.8 EON33879.1 - 0.093 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) HNH_5 PF14279.6 EON33880.1 - 3.5e-12 46.0 1.6 5.2e-12 45.4 1.6 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EON33880.1 - 7.4e-12 45.3 4.4 1.2e-11 44.6 4.4 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EON33880.1 - 8.4e-07 28.8 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Abhydrolase_4 PF08386.10 EON33880.1 - 0.045 13.9 0.1 0.094 12.8 0.1 1.5 1 0 0 1 1 1 0 TAP-like protein Cys_rich_CPXG PF14255.6 EON33880.1 - 0.13 12.1 2.5 0.25 11.3 2.5 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG Bac_globin PF01152.21 EON33881.1 - 9.3e-37 125.9 0.0 1.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Alpha-amylase PF00128.24 EON33883.1 - 3.8e-64 217.4 0.0 6e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 EON33883.1 - 1.1e-05 25.6 0.1 3.4e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) 4HBT_2 PF13279.6 EON33885.1 - 4.1e-09 37.0 0.0 5.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EON33885.1 - 6.8e-06 26.3 0.1 1.2e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EON33885.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 2 0 0 2 2 2 0 Acyl-ACP thioesterase Molybdopterin PF00384.22 EON33886.1 - 2.2e-30 106.0 0.0 3e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EON33886.1 - 2.4e-18 66.2 0.0 3.9e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EON33886.1 - 3.2e-07 30.2 0.1 1.1e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Bac_GDH PF05088.12 EON33887.1 - 0 1701.3 0.0 0 1700.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 EON33887.1 - 0.14 11.9 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ABC_tran PF00005.27 EON33888.1 - 1.2e-52 178.0 0.0 2.1e-28 99.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON33888.1 - 3.1e-18 66.6 4.1 0.00021 21.2 0.1 4.5 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EON33888.1 - 1.3e-16 60.4 7.9 2.4e-14 53.1 6.8 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EON33888.1 - 8.8e-09 35.1 4.0 0.21 11.0 0.1 4.2 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON33888.1 - 1.5e-05 24.6 0.7 0.15 11.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EON33888.1 - 8.7e-05 22.6 0.3 0.15 12.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EON33888.1 - 0.00017 21.9 0.1 0.18 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EON33888.1 - 0.00024 20.9 4.1 0.12 12.0 0.1 3.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_24 PF13479.6 EON33888.1 - 0.00039 20.2 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EON33888.1 - 0.00048 20.2 0.8 0.26 11.3 0.0 2.7 3 0 0 3 3 2 1 Dynamin family RsgA_GTPase PF03193.16 EON33888.1 - 0.0005 20.0 0.4 0.25 11.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 EON33888.1 - 0.00062 20.0 0.1 0.41 10.9 0.1 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EON33888.1 - 0.00082 19.9 2.7 0.013 16.0 0.6 3.6 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 EON33888.1 - 0.0027 18.1 1.3 0.29 11.6 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EON33888.1 - 0.0028 17.3 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EON33888.1 - 0.0042 17.0 0.6 0.34 10.8 0.0 3.0 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EON33888.1 - 0.0045 17.5 4.6 0.63 10.6 0.0 3.8 3 2 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EON33888.1 - 0.0047 16.9 0.0 0.51 10.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 EON33888.1 - 0.0068 16.6 0.4 19 5.6 0.0 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EON33888.1 - 0.017 15.2 0.2 1.8 8.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain DLIC PF05783.11 EON33888.1 - 0.018 13.9 0.2 0.16 10.7 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 EON33888.1 - 0.019 14.7 0.5 4.1 7.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EON33888.1 - 0.025 15.0 4.9 1.5 9.2 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 EON33888.1 - 0.041 13.5 0.3 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EON33888.1 - 0.042 13.0 5.1 0.096 11.9 0.1 3.2 3 1 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.6 EON33888.1 - 0.047 13.9 0.0 6 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EON33888.1 - 0.059 13.0 0.0 5.2 6.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 EON33888.1 - 0.084 12.2 0.0 39 3.5 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EON33888.1 - 0.12 12.8 0.2 11 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EON33888.1 - 0.13 12.1 1.3 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 EON33888.1 - 0.22 11.3 0.5 6.7 6.4 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EON33888.1 - 0.25 10.9 0.5 3.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 EON33888.1 - 1.1 9.1 5.0 2.3 8.1 0.6 3.4 5 0 0 5 5 4 0 NTPase Glyco_hydro_26 PF02156.15 EON33889.1 - 2.2e-13 50.3 2.7 3e-13 49.9 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Glyco_hydro_cc PF11790.8 EON33889.1 - 0.0009 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SpoIIE PF07228.12 EON33890.1 - 9.9e-37 126.7 4.8 1.5e-36 126.1 4.8 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GAF PF01590.26 EON33890.1 - 6.7e-06 26.8 0.0 1.9e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EON33890.1 - 0.00026 21.3 0.6 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 EON33890.1 - 0.0021 18.4 0.0 0.0054 17.1 0.0 1.7 1 1 0 1 1 1 1 GAF domain PP2C_2 PF13672.6 EON33890.1 - 0.0059 16.3 5.4 0.024 14.2 5.4 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Glycos_transf_2 PF00535.26 EON33891.1 - 2.1e-24 86.3 0.0 4e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 EON33891.1 - 7.3e-18 64.4 0.8 2.7e-17 62.6 0.7 1.9 1 1 0 1 1 1 1 Cellulose synthase Glyco_trans_2_3 PF13632.6 EON33891.1 - 1.6e-16 60.8 13.4 3.9e-11 43.2 3.9 3.7 3 1 0 3 3 3 2 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EON33891.1 - 3.3e-15 56.6 0.0 5e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EON33891.1 - 3.7e-10 39.6 0.0 4.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 ApoLp-III PF07464.11 EON33891.1 - 0.018 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Secapin PF17521.2 EON33891.1 - 0.019 14.7 0.2 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 Honey bee peptides STAS_2 PF13466.6 EON33892.1 - 1.5e-17 63.7 0.6 2.1e-17 63.2 0.6 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 EON33892.1 - 7.8e-16 57.8 0.0 8.7e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 STAS domain DUF4325 PF14213.6 EON33892.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) HATPase_c_2 PF13581.6 EON33893.1 - 4.4e-16 59.0 0.3 5.2e-16 58.7 0.3 1.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain SSB PF00436.25 EON33894.1 - 9.2e-18 64.2 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family CM_2 PF01817.21 EON33895.1 - 8.3e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Chorismate mutase type II Caa3_CtaG PF09678.10 EON33896.1 - 2.9e-85 285.4 25.1 2.9e-85 285.4 25.1 3.4 2 1 0 3 3 3 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) CopD PF05425.13 EON33896.1 - 1e-20 74.1 9.5 1e-20 74.1 9.5 6.7 4 3 2 6 6 6 2 Copper resistance protein D Abhydrolase_8 PF06259.12 EON33898.1 - 0.0005 19.8 4.9 0.0042 16.7 4.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase WXG100 PF06013.12 EON33898.1 - 0.12 12.6 0.8 0.53 10.5 1.1 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Xan_ur_permease PF00860.20 EON33899.1 - 4.3e-74 249.5 36.0 1e-73 248.3 36.0 1.5 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EON33899.1 - 5.8 7.4 39.8 0.12 12.7 11.8 3.4 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily Vir_act_alpha_C PF10400.9 EON33900.1 - 1.5e-22 80.0 0.1 2.9e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Virulence activator alpha C-term PadR PF03551.14 EON33900.1 - 4.9e-15 55.2 0.0 8.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family RTP PF02334.16 EON33900.1 - 0.0021 18.7 0.0 0.0033 18.0 0.0 1.2 1 0 0 1 1 1 1 Replication terminator protein TrmB PF01978.19 EON33900.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Oxidored_FMN PF00724.20 EON33901.1 - 5.3e-72 242.9 0.0 7.4e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 EON33901.1 - 3.1e-24 85.7 0.4 5.2e-24 85.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON33901.1 - 6.4e-09 35.9 0.2 2.2e-08 34.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EON33901.1 - 2.1e-07 30.7 0.6 4.4e-07 29.6 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON33901.1 - 3e-07 30.9 5.4 0.002 18.6 1.5 4.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON33901.1 - 5.7e-07 28.6 2.1 1.3e-06 27.4 2.1 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EON33901.1 - 2.9e-06 26.6 4.1 7.5e-06 25.3 4.1 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EON33901.1 - 9.5e-06 25.1 4.9 0.041 13.1 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON33901.1 - 2.4e-05 23.6 0.2 4.1e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FMO-like PF00743.19 EON33901.1 - 8e-05 21.2 0.2 0.029 12.8 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 EON33901.1 - 0.00024 20.8 2.9 0.00024 20.8 2.9 4.5 5 1 0 5 5 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON33901.1 - 0.00068 19.0 2.4 0.00075 18.9 0.5 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EON33901.1 - 0.0011 18.3 0.4 0.0032 16.7 0.2 1.8 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EON33901.1 - 0.0011 18.2 0.3 0.075 12.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EON33901.1 - 0.0038 17.1 0.1 0.1 12.5 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EON33901.1 - 0.011 15.0 1.0 0.065 12.5 0.5 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 EON33901.1 - 0.036 13.3 0.3 0.036 13.3 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Dus PF01207.17 EON33901.1 - 0.043 12.9 0.1 0.11 11.5 0.1 1.6 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Lycopene_cycl PF05834.12 EON33901.1 - 0.056 12.5 0.9 0.1 11.7 0.9 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein PH_18 PF18469.1 EON33901.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain 2-Hacid_dh_C PF02826.19 EON33901.1 - 0.17 11.2 0.5 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EON33901.1 - 1.2 9.1 5.2 3 7.8 0.5 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding adh_short PF00106.25 EON33902.1 - 4.5e-46 156.8 0.1 5.7e-46 156.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON33902.1 - 3.2e-28 98.9 0.5 3.7e-28 98.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON33902.1 - 9.2e-15 55.0 0.2 1.5e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON33902.1 - 3e-07 30.5 1.2 4.7e-07 29.9 1.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON33902.1 - 6.8e-07 29.0 0.0 9.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 EON33902.1 - 0.0011 19.0 1.4 0.0071 16.4 0.6 2.3 2 1 0 2 2 2 1 Glycosyltransferase Family 4 NmrA PF05368.13 EON33902.1 - 0.0017 18.0 0.3 0.51 9.8 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family DFP PF04127.15 EON33902.1 - 0.0022 17.9 1.3 0.004 17.0 0.2 1.9 2 1 1 3 3 3 1 DNA / pantothenate metabolism flavoprotein Pyr_redox PF00070.27 EON33902.1 - 0.0027 18.2 0.3 0.0067 17.0 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 EON33902.1 - 0.011 16.2 6.0 0.019 15.4 3.9 2.3 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Pyr_redox_2 PF07992.14 EON33902.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 EON33902.1 - 0.031 13.7 0.0 0.093 12.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EON33902.1 - 0.035 13.2 0.2 0.053 12.6 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 EON33902.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_5 PF08323.11 EON33902.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF853 PF05872.12 EON33903.1 - 3.1e-186 619.9 0.1 7.6e-186 618.6 0.1 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 EON33903.1 - 6.2e-10 39.6 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 EON33903.1 - 5.6e-06 25.5 0.0 8.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EON33903.1 - 3.5e-05 24.2 0.3 0.0023 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 EON33903.1 - 4.7e-05 23.5 0.0 0.004 17.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EON33903.1 - 0.0013 19.0 0.2 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EON33903.1 - 0.0023 17.3 0.2 0.0055 16.1 0.1 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EON33903.1 - 0.0077 16.0 0.1 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EON33903.1 - 0.0089 15.8 0.2 1.9 8.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.29 EON33903.1 - 0.019 15.4 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EON33903.1 - 0.052 12.8 0.1 0.084 12.1 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EON33903.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EON33903.1 - 0.081 13.0 0.0 0.23 11.5 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EON33903.1 - 0.1 12.9 0.1 0.47 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 EON33903.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) T2SSE PF00437.20 EON33903.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_6 PF12774.7 EON33903.1 - 0.17 10.8 0.1 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EON33903.1 - 0.18 11.3 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EON33903.1 - 0.22 11.4 0.2 0.4 10.6 0.2 1.4 1 0 0 1 1 1 0 NTPase RNase_T PF00929.24 EON33904.1 - 1.1e-32 113.9 0.0 1.2e-32 113.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease YCII PF03795.14 EON33905.1 - 8.8e-15 54.9 0.0 9.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Prot_ATP_ID_OB PF16450.5 EON33905.1 - 0.051 13.5 0.3 0.16 12.0 0.1 1.9 1 1 1 2 2 2 0 Proteasomal ATPase OB C-terminal domain Exotox-A_bind PF09101.10 EON33905.1 - 0.15 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A binding Sigma70_r2 PF04542.14 EON33906.1 - 9.8e-11 41.3 2.1 2.1e-10 40.2 0.9 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON33906.1 - 4.6e-08 32.6 0.1 1.4e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON33906.1 - 2.1e-05 23.9 0.0 0.00019 20.9 0.1 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_2 PF07719.17 EON33906.1 - 0.0093 16.0 0.4 0.069 13.3 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EON33906.1 - 0.037 14.3 2.9 5.3 7.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EON33906.1 - 0.07 14.0 15.3 0.61 11.1 0.7 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EON33906.1 - 0.077 12.8 0.6 0.42 10.5 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EON33906.1 - 0.093 12.8 0.4 0.9 9.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SDF PF00375.18 EON33907.1 - 3.1e-89 299.7 43.6 3.6e-89 299.5 43.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FlgI PF02119.16 EON33908.1 - 0.19 10.6 0.1 0.19 10.6 0.1 1.0 1 0 0 1 1 1 0 Flagellar P-ring protein Ceramidase_alk PF04734.13 EON33909.1 - 1.7e-150 502.1 0.0 5.7e-150 500.3 0.0 1.7 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EON33909.1 - 2.8e-48 163.9 0.0 4.7e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal TAT_signal PF10518.9 EON33909.1 - 0.011 15.6 5.3 0.011 15.6 5.3 3.4 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Big_10 PF17964.1 EON33910.1 - 6.6e-68 228.3 1.0 9.8e-68 227.7 1.0 1.3 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 EON33910.1 - 7.1e-18 65.4 0.2 1.3e-17 64.6 0.2 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF4342 PF14242.6 EON33910.1 - 2 8.5 4.7 36 4.4 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) DUF3618 PF12277.8 EON33911.1 - 5.7e-15 55.3 6.9 7.5e-15 54.9 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) AhpC-TSA PF00578.21 EON33912.1 - 1.3e-39 134.9 0.0 1.5e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EON33912.1 - 3.5e-27 94.9 0.0 4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EON33912.1 - 5e-05 23.4 0.0 0.00011 22.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 EON33912.1 - 0.00035 20.2 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 EON33912.1 - 0.00064 19.6 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 SCO1/SenC GSHPx PF00255.19 EON33912.1 - 0.042 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase TetR_C_22 PF17928.1 EON33913.1 - 2.6e-29 101.8 0.7 4.4e-29 101.1 0.7 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EON33913.1 - 6.9e-14 52.5 2.6 6.9e-14 52.5 2.6 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON33913.1 - 1.5e-12 47.1 0.0 2.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_16 PF17920.1 EON33913.1 - 0.006 16.8 2.8 0.011 16.0 2.8 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_20 PF17925.1 EON33913.1 - 0.028 14.7 0.6 0.051 13.9 0.6 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 EON33913.1 - 0.067 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF4803 PF16061.5 EON33913.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) ACPS PF01648.20 EON33914.1 - 1.3e-18 67.2 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EON33914.1 - 0.057 13.5 2.0 2.2 8.4 0.1 2.3 2 1 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain DUF1729 PF08354.10 EON33915.1 - 1.7e-114 382.4 0.0 2.5e-114 381.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EON33915.1 - 1.5e-39 136.4 11.4 8.9e-35 120.7 0.8 4.8 4 1 1 5 5 5 2 Acyl transferase domain ketoacyl-synt PF00109.26 EON33915.1 - 5.9e-31 107.9 3.7 6e-31 107.9 1.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EON33915.1 - 5.5e-28 97.4 0.0 1.4e-27 96.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydratas PF01575.19 EON33915.1 - 9.9e-25 86.5 0.0 2.7e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DNA_pol_B_N PF18094.1 EON33915.1 - 2.6e-21 76.1 0.2 2.6e-21 76.1 0.2 2.3 2 0 0 2 2 2 1 DNA polymerase beta N-terminal domain SAT PF16073.5 EON33915.1 - 2.9e-10 40.3 1.5 1.6e-09 37.9 0.1 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short PF00106.25 EON33915.1 - 0.00037 20.0 0.5 0.0042 16.6 0.2 2.6 2 0 0 2 2 2 1 short chain dehydrogenase FAS_I_H PF18314.1 EON33915.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EON33915.1 - 0.0032 17.8 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain Adenine_deam_C PF13382.6 EON33915.1 - 0.061 12.7 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain HIT PF01230.23 EON33916.1 - 2.4e-23 82.7 0.0 3.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EON33916.1 - 2e-10 41.1 0.0 2.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Enterotoxin_HS1 PF08090.11 EON33916.1 - 0.15 12.1 0.6 0.28 11.2 0.6 1.4 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 SIR2 PF02146.17 EON33917.1 - 3.4e-48 163.9 0.0 4.1e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family PNTB PF02233.16 EON33917.1 - 0.0031 16.5 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit DUF35_N PF12172.8 EON33917.1 - 0.062 13.2 2.9 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 EON33917.1 - 0.099 12.7 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EON33917.1 - 0.19 11.9 2.3 0.64 10.2 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EON33917.1 - 1.4 8.8 3.4 20 5.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain MTES_1575 PF18741.1 EON33918.1 - 1.9e-22 79.3 0.0 5.6e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 REase_MTES_1575 AAA_12 PF13087.6 EON33918.1 - 1e-17 64.4 0.0 2.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON33918.1 - 6e-14 52.2 0.6 2.4e-07 30.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EON33918.1 - 7.4e-13 48.9 0.0 3.9e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EON33918.1 - 5.8e-10 39.7 0.1 0.0001 22.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 EON33918.1 - 7.2e-06 26.0 0.2 0.0052 16.7 0.0 2.4 2 0 0 2 2 2 2 Helicase DUF559 PF04480.12 EON33918.1 - 1.7e-05 24.6 0.1 4.7e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF559) UvrD-helicase PF00580.21 EON33918.1 - 0.0001 21.9 0.0 0.032 13.8 0.1 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EON33918.1 - 0.00012 22.4 0.2 0.0021 18.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EON33918.1 - 0.00023 21.6 0.4 0.00023 21.6 0.4 4.0 4 2 0 4 4 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 EON33918.1 - 0.00059 19.6 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EON33918.1 - 0.00094 19.2 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EON33918.1 - 0.0064 15.8 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EON33918.1 - 0.012 15.3 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EON33918.1 - 0.019 15.1 0.1 0.065 13.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EON33918.1 - 0.026 13.5 0.9 0.054 12.4 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EON33918.1 - 0.029 14.8 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EON33918.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 EON33918.1 - 0.047 12.7 0.1 0.14 11.1 0.1 1.8 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 EON33918.1 - 0.059 12.8 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_31 PF13614.6 EON33918.1 - 0.079 12.9 0.1 5.6 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EON33918.1 - 0.1 12.5 0.6 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain CbiA PF01656.23 EON33918.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rhodanese PF00581.20 EON33919.1 - 3.4e-08 34.0 0.0 3.6e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain DEAD PF00270.29 EON33920.1 - 1.4e-49 168.2 0.1 7.8e-48 162.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON33920.1 - 1.9e-30 105.4 0.0 1.5e-29 102.6 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 EON33920.1 - 1.1e-21 76.6 0.1 3.7e-21 74.9 0.1 2.0 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 EON33920.1 - 1.4e-05 25.2 0.0 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrA_inter PF17760.1 EON33920.1 - 0.0004 20.4 0.2 0.00089 19.3 0.2 1.6 1 0 0 1 1 1 1 UvrA interaction domain HEM4 PF02602.15 EON33920.1 - 0.0016 17.8 1.2 0.023 14.1 0.4 2.3 1 1 0 2 2 2 1 Uroporphyrinogen-III synthase HemD AAA_22 PF13401.6 EON33920.1 - 0.051 13.9 1.3 1.4 9.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain adh_short PF00106.25 EON33920.1 - 0.1 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase AMP-binding PF00501.28 EON33921.1 - 3.9e-94 315.6 0.4 5.1e-94 315.3 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON33921.1 - 0.031 15.3 0.0 0.085 13.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain OpgC_C PF10129.9 EON33922.1 - 3.1e-36 125.0 37.9 6.3e-36 124.0 37.9 1.4 1 1 0 1 1 1 1 OpgC protein Acyl_transf_3 PF01757.22 EON33922.1 - 4.8e-06 25.9 42.2 6.5e-06 25.4 42.2 1.1 1 0 0 1 1 1 1 Acyltransferase family PetG PF02529.15 EON33922.1 - 0.059 13.2 0.1 0.26 11.2 0.1 2.1 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Cys_Met_Meta_PP PF01053.20 EON33923.1 - 1.9e-100 336.1 0.0 2.4e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EON33923.1 - 1e-10 41.3 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EON33923.1 - 4.6e-07 29.5 0.4 7.4e-07 28.8 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EON33923.1 - 5e-07 29.0 0.1 7.5e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EON33923.1 - 0.062 11.8 0.3 0.26 9.8 0.0 1.8 2 0 0 2 2 2 0 Methionine gamma-lyase MTS PF05175.14 EON33924.1 - 1.2e-15 57.5 0.0 4.5e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EON33924.1 - 3.1e-07 31.0 0.0 1.4e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON33924.1 - 2.7e-06 27.9 0.0 9.4e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON33924.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EON33924.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EON33924.1 - 0.014 15.3 0.0 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EON33924.1 - 0.019 14.8 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EON33924.1 - 0.022 15.5 0.0 0.098 13.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 EON33924.1 - 0.049 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.14 EON33924.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1524 PF07510.11 EON33925.1 - 5.8e-14 52.1 0.0 7.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EON33925.1 - 0.025 14.5 0.0 0.19 11.7 0.0 2.2 2 1 0 2 2 2 0 HNH endonuclease Lsr2 PF11774.8 EON33927.1 - 2.5e-29 101.6 0.2 2.9e-29 101.4 0.2 1.0 1 0 0 1 1 1 1 Lsr2 Rad52_Rad22 PF04098.15 EON33928.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein PQQ_2 PF13360.6 EON33929.1 - 1.1e-15 57.9 11.1 4.4e-10 39.6 7.4 3.0 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 EON33929.1 - 7.1e-13 47.8 6.8 0.16 12.0 0.1 7.2 6 1 1 7 7 7 5 PQQ enzyme repeat PQQ_3 PF13570.6 EON33929.1 - 2.4 8.7 20.4 14 6.4 1.7 6.8 6 1 1 7 7 7 0 PQQ-like domain SURF1 PF02104.15 EON33931.1 - 0.081 13.2 5.6 0.87 9.8 1.3 2.3 1 1 1 2 2 2 0 SURF1 family DUF3817 PF12823.7 EON33932.1 - 3.7e-27 95.0 7.1 4.6e-27 94.7 7.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) Glycos_transf_1 PF00534.20 EON33933.1 - 6.7e-20 71.3 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON33933.1 - 5.8e-19 68.8 0.0 1.1e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON33933.1 - 1.6e-13 51.4 13.8 1.6e-13 51.4 13.8 2.5 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EON33933.1 - 7.1e-11 42.4 1.4 1.4e-10 41.5 1.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EON33933.1 - 0.00028 21.2 0.2 0.0017 18.7 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EON33933.1 - 0.026 14.5 0.0 0.071 13.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like DUF3880 PF12996.7 EON33933.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) TetR_N PF00440.23 EON33934.1 - 1.3e-16 60.1 2.1 1.7e-16 59.7 0.7 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_28 PF17937.1 EON33934.1 - 6.5e-15 55.4 7.1 6.5e-15 55.4 7.1 1.9 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_20 PF12840.7 EON33934.1 - 0.0037 17.3 0.2 0.013 15.6 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 EON33934.1 - 0.019 14.8 1.0 0.061 13.1 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_18 PF12833.7 EON33934.1 - 0.038 14.3 0.2 0.091 13.0 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Ad_Cy_reg PF16701.5 EON33934.1 - 0.048 13.4 1.1 0.2 11.4 0.3 2.0 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain Sigma70_r3 PF04539.16 EON33934.1 - 0.15 12.2 0.3 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 Sigma-70 region 3 Acetyltransf_1 PF00583.25 EON33935.1 - 1.7e-05 25.0 0.0 3.4e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON33935.1 - 9.8e-05 22.3 0.0 0.00043 20.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON33935.1 - 0.00024 21.5 0.1 0.0042 17.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON33935.1 - 0.002 18.2 0.1 0.88 9.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON33935.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ham1p_like PF01725.16 EON33936.1 - 5.2e-59 199.3 0.0 5.8e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RNase_PH PF01138.21 EON33937.1 - 9.4e-24 84.4 0.2 2.4e-23 83.1 0.0 1.7 2 1 1 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EON33937.1 - 8.4e-09 35.3 0.1 1.6e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lactamase_B_2 PF12706.7 EON33938.1 - 7.6e-24 84.3 0.3 1e-23 83.9 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EON33938.1 - 1.3e-08 35.1 1.7 2e-08 34.5 1.7 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EON33938.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Asp_Glu_race PF01177.22 EON33939.1 - 1.4e-28 100.2 0.0 1.8e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Bombinin PF05298.11 EON33939.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bombinin Rhomboid PF01694.22 EON33940.1 - 3.1e-22 79.2 11.6 3.1e-22 79.2 11.6 1.4 2 0 0 2 2 2 1 Rhomboid family DUF5313 PF17240.2 EON33940.1 - 0.09 13.2 0.2 1.5 9.3 0.0 2.5 2 1 0 3 3 3 0 Family of unknown function (DUF5313) PALP PF00291.25 EON33941.1 - 8.4e-63 212.5 0.0 1.1e-62 212.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiS PF02597.20 EON33942.1 - 3.1e-19 69.4 0.1 3.6e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 EON33942.1 - 0.13 12.6 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Prok-JAB PF14464.6 EON33943.1 - 1.7e-28 98.8 0.5 1.9e-28 98.6 0.5 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 EON33943.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SpoIIP PF07454.11 EON33943.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S58 PF03576.14 EON33944.1 - 1.4e-68 231.7 16.5 1.7e-68 231.4 16.5 1.0 1 0 0 1 1 1 1 Peptidase family S58 DUF2017 PF09438.10 EON33945.1 - 4.9e-60 202.4 3.0 5.7e-60 202.2 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2017) ClpS PF02617.17 EON33946.1 - 2e-20 72.4 0.0 2.5e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DRTGG PF07085.12 EON33946.1 - 0.15 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 DRTGG domain NAPRTase_N PF17767.1 EON33947.1 - 1.2e-26 93.6 0.0 2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain QRPTase_C PF01729.19 EON33947.1 - 5.7e-07 29.5 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NAPRTase PF04095.16 EON33947.1 - 0.011 15.3 1.0 0.091 12.4 1.0 2.4 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Isochorismatase PF00857.20 EON33948.1 - 1.9e-29 103.1 0.3 2.2e-29 102.9 0.3 1.0 1 0 0 1 1 1 1 Isochorismatase family HTH_Crp_2 PF13545.6 EON33948.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Helicase_C_2 PF13307.6 EON33949.1 - 1.5e-27 96.8 0.0 2.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 EON33949.1 - 5.9e-11 42.4 0.3 6.5e-06 26.0 0.1 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EON33949.1 - 3.2e-05 24.0 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 EON33949.1 - 0.0015 18.2 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 AAA_30 PF13604.6 EON33949.1 - 0.013 15.3 6.9 0.57 9.9 0.7 3.6 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EON33949.1 - 0.015 15.7 0.0 0.055 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EON33949.1 - 0.11 11.8 0.2 0.69 9.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF3416 PF11896.8 EON33950.1 - 1.1e-49 169.1 3.2 1.8e-49 168.5 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Alpha-amylase PF00128.24 EON33950.1 - 0.00037 20.2 0.0 0.0029 17.2 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.6 EON33950.1 - 0.044 13.9 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 CBM_48 PF02922.18 EON33951.1 - 4.4e-26 91.0 0.1 3.9e-21 75.2 0.1 2.9 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 EON33951.1 - 1.1e-18 67.4 0.0 2.4e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EON33951.1 - 8.8e-13 48.5 0.1 1.5e-07 31.4 0.0 2.9 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EON33951.1 - 0.012 13.9 0.2 0.083 11.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 AMPK1_CBM PF16561.5 EON33951.1 - 0.019 15.2 0.1 0.06 13.6 0.1 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Thioredoxin PF00085.20 EON33952.1 - 1.4e-24 86.0 0.0 2.2e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TPR_20 PF14561.6 EON33952.1 - 4.3e-17 62.2 1.2 4.3e-17 62.2 1.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TraF PF13728.6 EON33952.1 - 9.9e-05 22.3 0.0 9.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EON33952.1 - 0.00037 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 EON33952.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EON33952.1 - 0.0014 18.9 0.0 0.074 13.4 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EON33952.1 - 0.0015 18.9 0.0 0.036 14.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EON33952.1 - 0.0037 16.7 0.0 0.005 16.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TPR_14 PF13428.6 EON33952.1 - 0.039 14.8 15.5 0.089 13.7 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF836 PF05768.14 EON33952.1 - 0.062 13.7 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) KaiB PF07689.12 EON33952.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 KaiB domain TPR_16 PF13432.6 EON33952.1 - 2.3 8.9 19.0 0.34 11.6 2.8 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EON33952.1 - 3.8 8.1 12.6 2.3 8.8 0.5 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 EON33953.1 - 3.9e-17 62.2 48.9 3.1e-08 33.0 27.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EON33953.1 - 0.024 13.9 38.8 0.04 13.2 17.1 2.5 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB DUF3817 PF12823.7 EON33954.1 - 5.2e-19 68.8 3.2 9.5e-19 68.0 3.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3817) Thiolase_N PF00108.23 EON33955.1 - 3.8e-97 324.7 0.1 5.2e-97 324.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON33955.1 - 2e-41 140.5 3.5 3.7e-41 139.6 2.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON33955.1 - 5.3e-05 22.9 2.9 7.7e-05 22.4 0.3 2.5 2 2 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EON33955.1 - 0.0012 18.7 0.5 0.48 10.3 0.1 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyoxalase_4 PF13669.6 EON33956.1 - 6e-22 78.0 0.1 8.4e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EON33956.1 - 1.3e-13 51.2 0.0 1.6e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EON33956.1 - 1.4e-12 48.1 0.2 1.8e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EON33956.1 - 0.00015 22.5 0.2 0.00022 22.0 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EON33956.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1338 PF07063.13 EON33956.1 - 0.16 11.1 0.0 0.53 9.4 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1338) DivIVA PF05103.13 EON33957.1 - 1.8e-05 24.8 10.7 0.00099 19.2 5.6 5.1 1 1 4 5 5 5 3 DivIVA protein EcKinase PF02958.20 EON33957.1 - 0.087 12.1 4.8 0.11 11.8 3.8 1.6 1 1 1 2 2 2 0 Ecdysteroid kinase DUF3818 PF12825.7 EON33957.1 - 0.54 9.2 5.7 0.87 8.5 4.9 1.7 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Med9 PF07544.13 EON33957.1 - 8.3 6.6 8.9 3.6 7.7 0.2 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NucS PF01939.16 EON33958.1 - 1.6e-85 286.1 0.0 1.8e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Endonuclease NucS UPF0102 PF02021.17 EON33958.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 Glutaminase PF04960.15 EON33959.1 - 3.6e-115 384.1 0.0 4.3e-115 383.8 0.0 1.1 1 0 0 1 1 1 1 Glutaminase STAS PF01740.21 EON33959.1 - 4.6e-06 26.3 0.1 7.8e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EON33959.1 - 0.00039 20.7 1.5 0.00091 19.5 1.5 1.6 1 0 0 1 1 1 1 STAS domain Usp PF00582.26 EON33960.1 - 2.6e-27 96.1 4.1 4.9e-15 56.3 0.2 2.0 2 0 0 2 2 2 2 Universal stress protein family PEP-utilisers_N PF05524.13 EON33960.1 - 0.043 14.0 0.5 7.7 6.7 0.1 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal TetR_C_15 PF17918.1 EON33960.1 - 0.29 11.9 4.0 0.57 11.0 0.3 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Multi_Drug_Res PF00893.19 EON33961.1 - 5.8e-21 75.0 10.8 7.2e-21 74.7 10.8 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein PfkB PF00294.24 EON33962.1 - 2.6e-47 161.6 0.0 3.3e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HTH_3 PF01381.22 EON33962.1 - 0.0042 17.1 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON33962.1 - 0.02 15.2 0.8 0.068 13.5 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Fe-S_biosyn PF01521.20 EON33963.1 - 1.4e-18 67.1 0.0 1.7e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Gly_kinase PF02595.15 EON33964.1 - 1.1e-93 314.2 22.6 4.8e-51 173.9 12.5 2.0 1 1 1 2 2 2 2 Glycerate kinase family DUF1204 PF06721.11 EON33964.1 - 0.18 11.3 0.1 0.35 10.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1204) DUF3043 PF11241.8 EON33965.1 - 1.1e-61 207.9 7.0 1.4e-61 207.4 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) DUF2085 PF09858.9 EON33965.1 - 0.21 12.1 0.6 0.33 11.5 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) DBI_PRT PF02277.17 EON33966.1 - 4.3e-131 437.0 11.5 5.3e-131 436.7 11.5 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase CobU PF02283.16 EON33966.1 - 2.3e-41 141.2 0.0 4e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase CobS PF02654.15 EON33967.1 - 3.3e-43 148.3 24.4 3.9e-43 148.0 24.4 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase Aminotran_4 PF01063.19 EON33968.1 - 1.4e-36 126.4 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV GCV_T PF01571.21 EON33969.1 - 2.8e-80 269.4 0.0 3.5e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EON33969.1 - 4.1e-15 55.5 0.2 9.1e-15 54.4 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Peptidase_M17 PF00883.21 EON33970.1 - 6.1e-115 383.8 0.6 8.3e-115 383.3 0.6 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EON33970.1 - 2.5e-22 79.0 0.6 1.5e-21 76.5 0.2 2.2 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain 2-oxoacid_dh PF00198.23 EON33971.1 - 8.9e-76 254.4 0.1 1.2e-75 254.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EON33971.1 - 1e-43 147.0 7.8 2.3e-21 75.4 0.8 3.1 3 0 0 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.17 EON33971.1 - 3.7e-16 59.2 0.6 1.8e-15 57.0 0.2 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EON33971.1 - 8.2e-07 28.8 2.3 0.23 11.3 0.0 4.5 2 2 2 4 4 4 2 Biotin-lipoyl like HlyD_3 PF13437.6 EON33971.1 - 1.4e-06 28.9 5.3 2.3 8.9 0.1 4.8 2 2 2 4 4 4 3 HlyD family secretion protein Trypan_PARP PF05887.11 EON33971.1 - 1.7e-06 28.1 50.8 1.4e-05 25.1 30.4 3.4 3 0 0 3 3 3 2 Procyclic acidic repetitive protein (PARP) GCV_H PF01597.19 EON33971.1 - 2.5e-06 27.4 3.3 0.089 12.7 0.1 3.4 3 0 0 3 3 3 2 Glycine cleavage H-protein TonB_N PF16031.5 EON33971.1 - 0.0008 19.9 25.0 0.0008 19.9 25.0 3.4 3 0 0 3 3 3 1 TonB polyproline region RnfC_N PF13375.6 EON33971.1 - 0.0028 17.6 0.3 3 7.8 0.0 2.8 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 EON33971.1 - 0.011 15.5 0.1 3.3 7.5 0.0 2.8 2 1 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 EON33971.1 - 0.1 12.3 0.1 26 4.6 0.0 3.2 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF1731 PF08338.11 EON33972.1 - 2.9e-16 59.0 0.1 9.7e-16 57.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 EON33972.1 - 6e-10 39.0 0.0 2.5e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON33972.1 - 2e-06 27.8 0.0 4.4e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON33972.1 - 0.0007 19.1 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 EON33972.1 - 0.042 14.3 2.8 0.28 11.6 0.3 2.6 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain NmrA PF05368.13 EON33972.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.4 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 EON33972.1 - 0.093 11.8 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain BPL_LplA_LipB PF03099.19 EON33973.1 - 3.3e-07 30.3 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Radical_SAM PF04055.21 EON33974.1 - 1.2e-13 51.8 0.0 2.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EON33974.1 - 2.9e-06 27.7 0.1 4.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family DUF4191 PF13829.6 EON33975.1 - 1.6e-88 295.7 1.1 2.1e-88 295.4 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) DUF2207 PF09972.9 EON33975.1 - 9.3e-05 21.4 0.1 0.00012 21.0 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Trep_Strep PF09605.10 EON33975.1 - 0.0015 18.5 0.8 0.002 18.1 0.8 1.2 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4083 PF13314.6 EON33975.1 - 0.32 11.0 1.4 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) RDD PF06271.12 EON33976.1 - 9.5e-06 25.9 6.2 0.00044 20.5 6.2 2.3 1 1 0 1 1 1 1 RDD family Gln-synt_C PF00120.24 EON33977.1 - 1.1e-136 455.3 0.0 1.3e-136 455.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EON33977.1 - 5e-28 96.6 0.1 8.8e-28 95.9 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Prot_ATP_ID_OB PF16450.5 EON33979.1 - 0.084 12.8 1.7 13 5.8 0.0 2.9 2 1 1 3 3 3 0 Proteasomal ATPase OB C-terminal domain Heme_oxygenase PF01126.20 EON33980.1 - 1.5e-47 162.1 0.0 1.7e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Heme oxygenase Spore_SspJ PF09575.10 EON33980.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Exo_endo_phos PF03372.23 EON33981.1 - 6.4e-09 35.7 0.5 9.3e-09 35.1 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2755 PF10954.8 EON33981.1 - 0.12 12.3 1.4 0.23 11.4 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) GlnE PF03710.15 EON33982.1 - 3e-96 321.7 11.2 1.1e-62 211.8 0.1 4.0 3 1 1 4 4 4 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 EON33982.1 - 6.3e-54 182.0 9.5 1.2e-31 109.8 6.7 2.6 2 0 0 2 2 2 2 GlnD PII-uridylyltransferase DUF294 PF03445.13 EON33982.1 - 9.8e-07 28.7 0.0 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 2 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 EON33982.1 - 0.00096 19.0 1.9 0.25 11.1 0.4 2.7 2 0 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain Gln-synt_C PF00120.24 EON33983.1 - 1.2e-123 412.5 0.0 1.4e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EON33983.1 - 2e-24 85.1 0.0 6.8e-24 83.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 EON33983.1 - 0.00092 19.0 0.0 0.0077 16.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain Pantoate_transf PF02548.15 EON33984.1 - 1.7e-109 365.2 1.2 2e-109 364.9 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EON33984.1 - 1e-05 25.1 1.8 3.7e-05 23.3 1.8 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Abhydrolase_1 PF00561.20 EON33985.1 - 6.8e-30 104.6 0.1 9.4e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON33985.1 - 5.9e-10 38.8 0.0 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EON33985.1 - 0.0075 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 EON33985.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family CHAD PF05235.14 EON33986.1 - 8.1e-49 166.6 7.0 8.1e-49 166.6 7.0 1.6 2 0 0 2 2 2 1 CHAD domain CYTH PF01928.21 EON33986.1 - 2.2e-16 60.3 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 CYTH domain RNB PF00773.19 EON33987.1 - 2.8e-40 138.6 0.0 3.7e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 RNB domain RNase_II_C_S1 PF18614.1 EON33987.1 - 6.9e-16 57.9 7.4 6.9e-16 57.9 7.4 2.3 2 0 0 2 2 2 1 RNase II-type exonuclease C-terminal S1 domain His_Phos_1 PF00300.22 EON33988.1 - 8e-58 195.3 0.2 9.7e-58 195.1 0.2 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3404 PF11884.8 EON33988.1 - 0.024 13.9 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) PCP_red PF08369.10 EON33988.1 - 6.7 7.0 7.1 2.8 8.2 3.7 2.2 2 1 1 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit zf-RING_7 PF02591.15 EON33989.1 - 4.8e-12 45.8 2.5 1.5e-11 44.3 2.5 1.9 1 0 0 1 1 1 1 C4-type zinc ribbon domain TMF_TATA_bd PF12325.8 EON33989.1 - 0.001 19.3 10.3 0.0035 17.6 4.9 2.7 2 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DNA_RNApol_7kD PF03604.13 EON33989.1 - 0.1 12.3 2.2 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ATG16 PF08614.11 EON33989.1 - 0.11 12.8 13.5 0.068 13.4 7.0 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4578 PF15147.6 EON33989.1 - 0.16 12.9 0.1 0.27 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Spc7 PF08317.11 EON33989.1 - 0.2 10.5 7.5 0.3 9.9 6.9 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Stathmin PF00836.19 EON33989.1 - 0.62 10.0 10.5 0.25 11.3 2.8 2.3 1 1 1 2 2 2 0 Stathmin family Atg14 PF10186.9 EON33989.1 - 1 8.4 6.4 0.74 8.9 4.4 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 EON33989.1 - 1.3 9.8 8.3 8.4 7.2 3.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DivIC PF04977.15 EON33989.1 - 1.7 8.4 9.9 7 6.5 0.6 3.4 2 2 0 3 3 3 0 Septum formation initiator DUF3584 PF12128.8 EON33989.1 - 3.8 4.9 10.6 1 6.8 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Osmo_CC PF08946.10 EON33989.1 - 6.5 7.1 9.8 25 5.2 0.1 4.2 4 2 1 5 5 5 0 Osmosensory transporter coiled coil NIF3 PF01784.18 EON33990.1 - 4.4e-72 242.7 0.0 5.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Aminotran_1_2 PF00155.21 EON33991.1 - 1.7e-31 109.7 0.0 2.1e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HAD_2 PF13419.6 EON33992.1 - 1.2e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON33992.1 - 2.3e-12 47.6 0.3 3.6e-11 43.8 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON33992.1 - 1.2e-10 42.1 0.2 1.7e-10 41.6 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON33992.1 - 7.4e-08 32.3 0.1 1.6e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 EON33992.1 - 0.12 12.1 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LMWPc PF01451.21 EON33993.1 - 4e-35 121.3 0.0 4.6e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Peptidase_Mx PF15887.5 EON33994.1 - 3.5e-99 331.0 0.0 4.1e-99 330.7 0.0 1.1 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase zinc-ribbon_6 PF10005.9 EON33994.1 - 5e-18 65.6 1.0 8.1e-18 64.9 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_Mx1 PF15890.5 EON33994.1 - 0.00022 20.8 0.1 0.00041 19.8 0.1 1.4 1 1 0 1 1 1 1 Putative zinc-binding metallo-peptidase DZR PF12773.7 EON33994.1 - 0.77 9.8 4.1 11 6.1 4.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon SURF1 PF02104.15 EON33995.1 - 5.5e-24 85.4 0.0 9.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 SURF1 family CobD_Cbib PF03186.13 EON33996.1 - 5.3e-88 294.8 1.5 6.4e-88 294.6 1.5 1.1 1 0 0 1 1 1 1 CobD/Cbib protein Spermine_synth PF01564.17 EON33997.1 - 0.00015 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 EON33997.1 - 0.00035 21.2 0.0 0.0007 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 EON33997.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 EON33997.1 - 0.0068 17.4 0.1 0.014 16.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF1069 PF06370.11 EON33997.1 - 0.058 13.0 0.1 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1069) Pkinase PF00069.25 EON33998.1 - 1.8e-41 142.3 0.0 2.3e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON33998.1 - 8.8e-26 90.7 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pro_isomerase PF00160.21 EON33998.1 - 6.4e-10 39.5 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD APH PF01636.23 EON33998.1 - 2.9e-06 27.4 2.8 3.7e-05 23.8 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EON33998.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EON33998.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SKG6 PF08693.10 EON33998.1 - 0.19 11.1 8.3 0.39 10.2 8.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MDMPI_N PF11716.8 EON33999.1 - 2e-27 96.6 6.1 2e-27 96.6 6.1 1.7 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 EON33999.1 - 3.4e-12 47.1 6.6 3.4e-12 47.1 6.6 2.0 2 1 0 2 2 2 1 MDMPI C-terminal domain DinB_2 PF12867.7 EON33999.1 - 3.1e-08 34.2 0.5 6.9e-08 33.1 0.5 1.6 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 EON33999.1 - 0.0061 17.0 0.2 0.0091 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF664) Pkinase PF00069.25 EON34000.1 - 5.3e-40 137.4 0.0 6.6e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON34000.1 - 1.1e-25 90.4 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON34000.1 - 2.2e-08 34.3 5.8 1.9e-06 28.0 1.5 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EON34000.1 - 0.00037 19.9 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MARVEL PF01284.23 EON34000.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Membrane-associating domain Haspin_kinase PF12330.8 EON34000.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4006 PF13179.6 EON34000.1 - 0.41 10.6 1.2 0.7 9.8 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) WYL PF13280.6 EON34001.1 - 2.9e-33 115.3 0.6 4.4e-33 114.8 0.6 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EON34001.1 - 6.7e-16 58.0 0.2 1.2e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EON34001.1 - 5.4e-07 29.3 0.5 9.7e-07 28.4 0.5 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EON34001.1 - 3.1e-06 27.4 0.3 1.1e-05 25.7 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator HTH_23 PF13384.6 EON34001.1 - 0.00027 20.6 2.0 0.0016 18.2 0.3 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.7 EON34001.1 - 0.0014 18.7 2.8 0.014 15.5 0.4 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EON34001.1 - 0.0027 17.2 0.3 0.0059 16.1 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HrcA_DNA-bdg PF03444.15 EON34001.1 - 0.0032 17.1 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_Mga PF08280.11 EON34001.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_5 PF01022.20 EON34001.1 - 0.028 14.3 0.2 0.52 10.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 EON34001.1 - 0.034 14.3 0.4 0.12 12.5 0.1 2.1 2 0 0 2 2 1 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 EON34001.1 - 0.043 13.8 0.4 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus HTH_IclR PF09339.10 EON34001.1 - 0.052 13.4 2.9 0.064 13.1 1.2 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_36 PF13730.6 EON34001.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain WYL_2 PF10902.8 EON34001.1 - 0.069 13.5 0.4 0.73 10.3 0.4 2.2 2 0 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold Fe_dep_repress PF01325.19 EON34001.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 EON34001.1 - 0.14 12.2 2.1 0.28 11.3 0.2 2.4 3 0 0 3 3 2 0 Winged helix-turn helix HTH_32 PF13565.6 EON34001.1 - 1 10.1 8.5 0.2 12.3 1.3 2.9 2 0 0 2 2 2 0 Homeodomain-like domain NAD_binding_10 PF13460.6 EON34002.1 - 3.9e-17 62.7 0.8 8.2e-17 61.7 0.7 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON34002.1 - 1.7e-14 53.9 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON34002.1 - 4.3e-09 36.3 0.1 6.3e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EON34002.1 - 1.7e-07 31.0 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EON34002.1 - 1.2e-05 24.5 0.1 1.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EON34002.1 - 2.9e-05 23.6 0.1 4.4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EON34002.1 - 3e-05 23.3 0.0 4.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 EON34002.1 - 0.00085 19.6 0.1 0.018 15.3 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EON34002.1 - 0.0013 18.7 0.2 0.0023 17.9 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EON34002.1 - 0.005 16.1 0.1 0.0093 15.2 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EON34002.1 - 0.012 15.1 0.4 0.018 14.6 0.4 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 EON34002.1 - 0.055 13.7 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.15 EON34002.1 - 0.066 12.3 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EON34002.1 - 0.085 13.3 0.0 0.24 11.8 0.0 1.8 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EON34002.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CPBP PF02517.16 EON34003.1 - 1.8e-07 31.4 2.7 1.8e-07 31.4 2.7 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease MdcE PF06833.11 EON34003.1 - 0.055 12.9 2.5 0.1 12.1 2.5 1.4 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DUF4491 PF14898.6 EON34003.1 - 7.6 7.0 8.8 6.5 7.3 1.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) DUF2336 PF10098.9 EON34005.1 - 0.003 17.1 2.0 0.0051 16.3 2.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) EcKinase PF02958.20 EON34005.1 - 0.19 11.0 0.0 1.5 8.1 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase PIG-H PF10181.9 EON34007.1 - 0.0047 16.8 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component SpoIIM PF01944.17 EON34010.1 - 0.0088 16.1 0.9 0.013 15.5 0.9 1.2 1 0 0 1 1 1 1 Stage II sporulation protein M Questin_oxidase PF14027.6 EON34010.1 - 0.062 12.8 0.3 0.077 12.5 0.3 1.1 1 0 0 1 1 1 0 Questin oxidase-like DUF4131 PF13567.6 EON34010.1 - 0.29 10.8 5.3 0.11 12.2 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) 7TM_GPCR_Srh PF10318.9 EON34010.1 - 0.38 9.7 4.8 1.3 7.9 1.7 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF4231 PF14015.6 EON34010.1 - 8.8 6.9 10.9 19 5.8 5.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HAMP PF00672.25 EON34011.1 - 0.48 10.8 5.8 0.81 10.1 3.1 2.2 1 1 1 2 2 2 0 HAMP domain Sigma70_r2 PF04542.14 EON34012.1 - 3.3e-17 62.0 0.8 7e-17 61.0 0.8 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON34012.1 - 3.8e-09 36.1 0.0 6.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON34012.1 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON34012.1 - 0.023 14.6 1.9 0.056 13.3 1.9 1.7 1 1 0 1 1 1 0 ECF sigma factor Asp23 PF03780.13 EON34013.1 - 1.7e-29 102.4 9.5 2.1e-29 102.1 9.5 1.1 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function DUF1359 PF07097.11 EON34013.1 - 0.095 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Asp23 PF03780.13 EON34014.1 - 0.016 15.6 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function DUF2273 PF10031.9 EON34015.1 - 0.00045 20.2 8.0 0.00054 19.9 8.0 1.1 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) DUF3042 PF11240.8 EON34015.1 - 5.4 7.1 6.0 4.4 7.4 4.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3042) Asp23 PF03780.13 EON34016.1 - 3e-13 50.1 0.0 4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function Spore_YhcN_YlaJ PF09580.10 EON34017.1 - 0.0057 16.8 0.4 0.0082 16.2 0.4 1.1 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) CsbD PF05532.12 EON34019.1 - 2.4e-16 59.4 7.6 3.3e-16 58.9 7.6 1.2 1 0 0 1 1 1 1 CsbD-like YtxH PF12732.7 EON34019.1 - 0.0024 18.4 1.7 0.0034 17.9 1.7 1.3 1 0 0 1 1 1 1 YtxH-like protein RtcB PF01139.17 EON34020.1 - 3.4e-116 388.8 0.0 4.1e-115 385.3 0.0 1.9 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB AhpC-TSA PF00578.21 EON34021.1 - 2e-29 102.0 0.0 2.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EON34021.1 - 2.1e-20 72.9 0.0 2.3e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 EON34021.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) DUF3052 PF11253.8 EON34022.1 - 1.8e-54 182.9 7.3 2.1e-54 182.8 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) PDH_E1_M PF17831.1 EON34024.1 - 1.4e-114 381.4 0.2 2.3e-114 380.7 0.2 1.3 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 EON34024.1 - 1.2e-15 57.3 0.1 1.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EON34024.1 - 0.017 15.0 0.1 0.09 12.7 0.0 2.2 3 0 0 3 3 3 0 Transketolase, C-terminal domain HTH_30 PF13556.6 EON34025.1 - 1.6e-21 75.9 0.0 3.4e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EON34025.1 - 5e-13 49.3 1.4 1.1e-12 48.2 0.0 2.3 3 0 0 3 3 3 1 GGDEF-like domain HTH_8 PF02954.19 EON34025.1 - 0.0044 16.8 0.1 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Acyl_transf_1 PF00698.21 EON34026.1 - 1.2e-24 87.4 1.7 1.5e-24 87.1 1.7 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 EON34026.1 - 0.0063 16.3 1.9 0.0083 15.9 1.4 1.5 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis VirE_N PF08800.10 EON34026.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 VirE N-terminal domain PP-binding PF00550.25 EON34027.1 - 6.9e-16 58.4 0.2 9.1e-16 58.0 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ribosomal_L50 PF10501.9 EON34027.1 - 0.0038 17.4 0.0 0.0051 16.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal subunit 39S ketoacyl-synt PF00109.26 EON34028.1 - 5.8e-48 163.7 3.9 5.8e-48 163.7 3.9 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EON34028.1 - 2e-30 105.2 1.7 3.8e-30 104.3 1.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EON34028.1 - 4.3e-07 29.6 2.3 6.8e-07 28.9 1.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON34028.1 - 3 7.5 6.2 0.22 11.2 0.3 2.2 3 0 0 3 3 3 0 Thiolase, C-terminal domain Abhydrolase_6 PF12697.7 EON34028.1 - 9.2 6.8 14.5 0.11 13.1 2.1 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family Carboxyl_trans PF01039.22 EON34029.1 - 1.4e-122 409.9 4.0 1.8e-122 409.5 4.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EON34029.1 - 0.0002 20.9 11.0 0.00032 20.3 1.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) DUF3145 PF11343.8 EON34030.1 - 2.2e-69 232.0 0.5 2.5e-69 231.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) Beta-lactamase PF00144.24 EON34031.1 - 1.2e-34 120.0 0.2 5.5e-34 117.9 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EON34031.1 - 0.0026 17.2 0.0 0.42 10.0 0.0 2.0 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EON34031.1 - 0.014 15.0 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family ADH_N PF08240.12 EON34032.1 - 4.5e-29 100.5 1.1 4.5e-29 100.5 1.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON34032.1 - 8.7e-19 67.8 0.9 1.7e-18 66.9 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.9 EON34032.1 - 0.02 15.0 0.1 0.061 13.4 0.1 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ThiF PF00899.21 EON34032.1 - 0.18 11.1 0.3 0.33 10.3 0.3 1.3 1 0 0 1 1 1 0 ThiF family AMP-binding PF00501.28 EON34033.1 - 7.1e-104 347.7 0.1 8.5e-104 347.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34033.1 - 1e-19 71.3 1.5 2.3e-19 70.2 0.2 2.4 3 1 1 4 4 4 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 EON34034.1 - 3.1e-41 141.4 0.3 4.3e-41 140.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34034.1 - 6.1e-30 104.9 1.6 1e-27 97.5 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PE PF00934.20 EON34034.1 - 7.7 6.9 9.7 1.4 9.3 5.4 2.0 2 0 0 2 2 2 0 PE family TetR_N PF00440.23 EON34035.1 - 7.9e-31 105.6 7.2 2e-17 62.7 0.3 2.8 3 0 0 3 3 3 2 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON34035.1 - 2.2e-07 31.1 1.7 0.0019 18.4 0.1 2.3 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain HTH_IclR PF09339.10 EON34035.1 - 0.0011 18.7 0.5 0.86 9.5 0.0 4.0 5 0 0 5 5 5 1 IclR helix-turn-helix domain HTH_10 PF04967.12 EON34035.1 - 0.005 16.6 0.1 0.2 11.5 0.0 3.2 3 0 0 3 3 3 1 HTH DNA binding domain PRP38 PF03371.15 EON34035.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 PRP38 family HTH_AraC PF00165.23 EON34035.1 - 0.075 13.2 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DprA_WH PF17782.1 EON34035.1 - 0.088 12.9 3.3 3.3 7.9 0.0 3.9 4 0 0 4 4 4 0 DprA winged helix domain HTH_5 PF01022.20 EON34035.1 - 0.14 12.1 0.0 2.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family TetR_C_15 PF17918.1 EON34035.1 - 0.66 10.8 17.4 0.66 10.8 1.6 3.6 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2613 PF11021.8 EON34036.1 - 0.68 10.1 4.9 2.4 8.4 4.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Putative_PNPOx PF01243.20 EON34037.1 - 1.1e-07 31.9 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PEP_mutase PF13714.6 EON34038.1 - 4.9e-62 209.5 0.2 5.8e-62 209.3 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pantoate_transf PF02548.15 EON34038.1 - 0.0037 16.7 0.0 0.0084 15.5 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase RibD_C PF01872.17 EON34039.1 - 1.4e-10 41.4 0.0 2e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 RibD C-terminal domain NAD_binding_10 PF13460.6 EON34040.1 - 1.9e-18 67.0 5.3 3.9e-18 66.0 5.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EON34040.1 - 3.2e-17 62.9 0.0 4.4e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EON34040.1 - 3e-05 24.2 1.4 3.9e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 EON34040.1 - 3.1e-05 23.1 0.2 6.6e-05 22.0 0.2 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EON34040.1 - 0.00023 20.4 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EON34040.1 - 0.00026 21.2 0.1 0.00057 20.2 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EON34040.1 - 0.0016 17.9 1.8 0.0022 17.5 0.2 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON34040.1 - 0.0019 18.2 0.3 0.0019 18.2 0.3 1.9 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 EON34040.1 - 0.0057 17.2 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent HxlR PF01638.17 EON34041.1 - 5.8e-24 83.8 0.0 7e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EON34041.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EON34041.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Orai-1 PF07856.12 EON34043.1 - 0.055 13.1 0.5 0.095 12.4 0.5 1.4 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF1129 PF06570.11 EON34043.1 - 2.2 7.7 4.5 3.1 7.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 EON34044.1 - 0.0031 16.5 16.5 0.0031 16.5 16.5 4.8 2 2 1 3 3 3 1 Major Facilitator Superfamily PKS_DE PF18369.1 EON34044.1 - 0.24 12.0 1.2 26 5.5 0.3 2.8 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Isochorismatase PF00857.20 EON34045.1 - 2.4e-46 158.1 0.0 3e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Amidase PF01425.21 EON34046.1 - 1.1e-70 238.9 0.2 1.8e-70 238.1 0.2 1.4 1 1 0 1 1 1 1 Amidase FCD PF07729.12 EON34047.1 - 2.1e-21 76.6 8.9 4.4e-21 75.6 8.9 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EON34047.1 - 1.1e-18 66.6 2.8 2.8e-18 65.3 0.8 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 EON34047.1 - 0.00034 20.8 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 EON34047.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 EON34047.1 - 0.016 15.7 0.0 0.052 14.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 EON34047.1 - 0.018 14.9 0.7 0.079 12.9 0.1 2.2 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 EON34047.1 - 0.019 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TetR_C_30 PF17939.1 EON34047.1 - 0.021 15.0 0.3 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_IclR PF09339.10 EON34047.1 - 0.026 14.3 0.3 1 9.2 0.1 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 EON34047.1 - 0.037 13.6 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 EON34047.1 - 0.041 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 EON34047.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PaaX PF07848.12 EON34047.1 - 0.17 12.2 0.1 0.73 10.1 0.0 2.0 2 0 0 2 2 2 0 PaaX-like protein HTH_41 PF14502.6 EON34047.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RibD_C PF01872.17 EON34048.1 - 4.9e-17 62.4 0.1 5.8e-16 58.9 0.1 1.9 1 1 0 1 1 1 1 RibD C-terminal domain zf-CHC2 PF01807.20 EON34049.1 - 5.2e-35 119.2 0.0 8.8e-35 118.5 0.0 1.4 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_N PF08275.11 EON34049.1 - 8.9e-35 119.5 0.0 1.3e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain DnaG_DnaB_bind PF08278.11 EON34049.1 - 3.9e-26 92.1 0.0 2e-25 89.8 0.0 2.2 3 0 0 3 3 3 1 DNA primase DnaG DnaB-binding DnaB_bind PF10410.9 EON34049.1 - 1.7e-18 66.6 0.5 4.9e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 DnaB-helicase binding domain of primase Toprim_4 PF13662.6 EON34049.1 - 8.5e-15 55.0 0.1 1.8e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 EON34049.1 - 1.5e-08 35.0 0.0 3.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 EON34049.1 - 1.1e-06 28.8 0.1 2.2e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 EON34049.1 - 0.0021 18.4 0.9 0.0034 17.7 0.0 1.9 2 0 0 2 2 2 1 Toprim domain HD PF01966.22 EON34050.1 - 1e-18 67.7 0.0 2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_assoc PF13286.6 EON34050.1 - 7.8e-18 64.8 0.0 1.4e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Phosphohydrolase-associated domain HDOD PF08668.12 EON34050.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 HDOD domain CSD PF00313.22 EON34051.1 - 2.4e-16 59.3 0.1 3.3e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EON34051.1 - 0.0013 18.4 0.1 0.0034 17.0 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 EON34051.1 - 0.029 14.7 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 S1 RNA binding domain CusF_Ec PF11604.8 EON34051.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF HGTP_anticodon PF03129.20 EON34052.1 - 1.9e-24 85.7 0.0 3.9e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EON34052.1 - 5.9e-08 32.9 0.0 1.7e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_M28 PF04389.17 EON34053.1 - 6e-42 143.6 0.1 8.3e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EON34053.1 - 1.8e-13 50.3 1.6 5.7e-13 48.7 1.6 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EON34053.1 - 4.6e-06 26.5 0.2 1e-05 25.3 0.2 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HTH_5 PF01022.20 EON34054.1 - 4.2e-17 61.7 0.6 7.5e-17 60.9 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EON34054.1 - 1.3e-11 44.4 1.2 2.3e-11 43.6 1.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 EON34054.1 - 0.0004 19.9 0.0 0.00091 18.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON34054.1 - 0.0011 18.8 1.7 0.0019 18.0 1.0 1.8 1 1 0 1 1 1 1 MarR family HTH_41 PF14502.6 EON34054.1 - 0.002 17.7 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EON34054.1 - 0.0087 16.0 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain PaaX PF07848.12 EON34054.1 - 0.06 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Rrf2 PF02082.20 EON34054.1 - 0.08 13.3 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator FUR PF01475.19 EON34055.1 - 7.4e-33 113.2 0.0 8.3e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 EON34055.1 - 0.0051 16.7 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Peptidase_C23 PF05379.11 EON34055.1 - 0.019 15.1 0.1 5.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Carlavirus endopeptidase HTH_20 PF12840.7 EON34055.1 - 0.03 14.4 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PadR PF03551.14 EON34055.1 - 0.048 13.6 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MIB_HERC2 PF06701.13 EON34055.1 - 0.071 13.4 0.1 0.22 11.8 0.0 1.8 1 1 1 2 2 2 0 Mib_herc2 Rubredoxin_2 PF18073.1 EON34055.1 - 1.1 9.1 5.8 5.4 6.8 0.1 2.7 2 1 1 3 3 3 0 Rubredoxin metal binding domain Prenyltransf PF01255.19 EON34057.1 - 7e-71 238.3 0.0 8e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RecO_C PF02565.15 EON34058.1 - 1.2e-28 99.9 0.5 1.5e-28 99.5 0.5 1.1 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 EON34058.1 - 2.6e-27 94.6 0.1 1.6e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 Recombination protein O N terminal RecO_N_2 PF13114.6 EON34058.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 RecO N terminal ParD_antitoxin PF03693.14 EON34058.1 - 0.084 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH PK PF00224.21 EON34059.1 - 1.1e-49 169.2 0.0 1.1e-39 136.3 0.0 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain HisG_C PF08029.11 EON34059.1 - 0.035 14.3 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 HisG, C-terminal domain HpcH_HpaI PF03328.14 EON34059.1 - 0.064 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family CoA_binding_2 PF13380.6 EON34059.1 - 0.22 12.0 0.6 5 7.7 0.0 3.1 4 0 0 4 4 4 0 CoA binding domain DUF3533 PF12051.8 EON34060.1 - 1.8e-52 178.6 1.3 2.1e-52 178.3 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 EON34060.1 - 6.7e-15 55.0 17.5 1.5e-14 53.9 17.5 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EON34060.1 - 5.6e-05 22.7 22.6 5.6e-05 22.7 22.6 2.8 3 1 0 3 3 3 1 ABC-2 type transporter CPP1-like PF11833.8 EON34060.1 - 0.11 12.2 0.0 0.11 12.2 0.0 3.1 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF543 PF04418.12 EON34060.1 - 0.17 11.9 0.6 5.3 7.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) FA_desaturase PF00487.24 EON34060.1 - 8.1 6.2 10.9 2.9 7.7 3.9 2.6 3 0 0 3 3 3 0 Fatty acid desaturase MMR_HSR1 PF01926.23 EON34061.1 - 2.4e-20 72.7 0.0 4.1e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 EON34061.1 - 4.6e-18 64.8 0.1 9.1e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 EON34061.1 - 2.8e-10 39.9 0.1 1.5e-09 37.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EON34061.1 - 1.1e-08 35.3 0.1 4e-05 23.7 0.1 2.2 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EON34061.1 - 4.3e-08 33.2 0.0 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EON34061.1 - 3.6e-06 26.8 0.0 1.5e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EON34061.1 - 5.7e-06 26.0 0.1 0.021 14.4 0.1 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EON34061.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 EON34061.1 - 0.016 15.5 0.0 0.094 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EON34061.1 - 0.027 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EON34061.1 - 0.091 13.0 0.0 0.69 10.1 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EON34061.1 - 0.31 10.7 0.0 0.46 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain dCMP_cyt_deam_2 PF08211.12 EON34062.1 - 0.019 15.1 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF21 PF01595.20 EON34063.1 - 2.4e-31 108.8 1.9 3.4e-31 108.3 1.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EON34063.1 - 1.8e-12 47.1 1.2 2.9e-12 46.4 0.1 2.0 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EON34063.1 - 9.9e-11 41.9 2.5 0.00014 22.3 0.1 2.7 2 0 0 2 2 2 2 CBS domain DUF4282 PF14110.6 EON34063.1 - 0.92 10.3 8.0 0.12 13.1 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) UPF0054 PF02130.17 EON34064.1 - 1.4e-36 125.1 0.0 2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PhoH PF02562.16 EON34065.1 - 1.2e-94 315.5 0.0 1.5e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 EON34065.1 - 4e-11 43.0 0.1 6.2e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EON34065.1 - 8.9e-07 29.3 0.0 1.9e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EON34065.1 - 0.00029 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EON34065.1 - 0.0017 18.6 0.3 0.074 13.3 0.2 3.0 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 EON34065.1 - 0.0029 17.4 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 EON34065.1 - 0.0069 16.0 0.0 2.6 7.7 0.0 2.1 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) UvrD-helicase PF00580.21 EON34065.1 - 0.023 14.2 0.8 3.5 7.0 0.1 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 EON34065.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EON34065.1 - 0.17 11.0 0.1 0.54 9.4 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase Peptidase_S9 PF00326.21 EON34066.1 - 6e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EON34066.1 - 6.3e-10 39.3 1.7 2.2e-09 37.5 1.7 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON34066.1 - 3.4e-06 27.8 13.4 0.00052 20.7 8.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON34066.1 - 0.00012 21.5 1.3 0.036 13.3 0.6 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON34066.1 - 0.0025 17.5 0.6 0.9 9.1 0.3 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EON34066.1 - 0.049 13.4 0.0 0.87 9.3 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.18 EON34066.1 - 0.097 12.2 0.7 0.6 9.6 0.7 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EON34066.1 - 0.22 10.4 0.1 0.32 9.9 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme COesterase PF00135.28 EON34066.1 - 0.63 8.8 3.2 2 7.2 0.6 2.5 1 1 1 2 2 2 0 Carboxylesterase family Methyltrans_RNA PF04452.14 EON34067.1 - 1.1e-54 185.1 0.0 1.3e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase DnaJ_C PF01556.18 EON34068.1 - 9.7e-38 129.6 0.0 1.3e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EON34068.1 - 1.4e-22 79.5 0.2 1.4e-22 79.5 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EON34068.1 - 1.9e-12 47.3 12.5 3.4e-12 46.6 12.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EON34068.1 - 0.0024 17.8 1.0 0.0024 17.8 1.0 3.3 1 1 3 4 4 4 2 Tryptophan RNA-binding attenuator protein inhibitory protein Catalase-rel PF06628.12 EON34068.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Catalase-related immune-responsive HrcA PF01628.21 EON34069.1 - 2.2e-61 207.6 1.1 2.8e-61 207.2 1.1 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain HTH_DeoR PF08220.12 EON34069.1 - 6.3e-05 22.7 0.1 0.00022 20.9 0.0 2.0 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EON34069.1 - 0.00091 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HrcA_DNA-bdg PF03444.15 EON34069.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding baeRF_family10 PF18854.1 EON34069.1 - 0.0089 16.3 0.6 0.026 14.8 0.6 1.8 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 HTH_20 PF12840.7 EON34069.1 - 0.049 13.7 0.3 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HEAT_EZ PF13513.6 EON34069.1 - 0.062 13.8 0.4 0.24 12.0 0.4 2.1 1 0 0 1 1 1 0 HEAT-like repeat GCSF PF16647.5 EON34070.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Radical_SAM PF04055.21 EON34071.1 - 8.2e-24 84.9 0.0 1.3e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 EON34071.1 - 2.6e-05 24.2 0.1 7.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 HemN C-terminal domain NIR_SIR PF01077.22 EON34072.1 - 8e-50 168.4 0.0 3.9e-38 130.5 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EON34072.1 - 9.3e-27 92.7 0.1 7.9e-14 51.3 0.0 3.3 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain PAPS_reduct PF01507.19 EON34073.1 - 2.8e-41 141.4 0.0 3.6e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.19 EON34074.1 - 8.3e-43 146.4 0.0 1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 EON34074.1 - 0.0046 16.5 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EON34074.1 - 0.0052 16.6 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Diphthami_syn_2 PF01902.17 EON34074.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Diphthamide synthase GTP_EFTU PF00009.27 EON34075.1 - 3.4e-40 137.7 0.1 5.3e-40 137.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EON34075.1 - 6.3e-07 29.5 0.2 2.3e-05 24.5 0.1 3.0 2 2 1 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 EON34075.1 - 0.0025 18.1 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain ATP_bind_1 PF03029.17 EON34075.1 - 0.0059 16.4 0.2 0.02 14.7 0.0 1.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.25 EON34075.1 - 0.0072 16.7 0.2 0.017 15.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EON34075.1 - 0.039 13.4 0.1 5.4 6.4 0.0 3.5 2 2 1 3 3 3 0 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 EON34075.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 cobW PF02492.19 EON34075.1 - 0.14 11.7 0.0 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiX PF01903.17 EON34076.1 - 2e-25 89.2 0.0 7.2e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 EON34076.1 - 0.04 13.2 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) Glyco_hydro_15 PF00723.21 EON34081.1 - 2.2e-51 175.1 0.0 1.7e-46 158.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Abhydrolase_3 PF07859.13 EON34082.1 - 4.9e-50 170.3 0.3 6.1e-50 170.0 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON34082.1 - 3.5e-12 45.9 0.0 4.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EON34082.1 - 2.8e-05 23.2 0.1 4.1e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EON34082.1 - 0.00082 18.7 0.0 0.002 17.4 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EON34082.1 - 0.015 14.8 0.0 0.049 13.1 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 EON34082.1 - 0.031 14.4 0.1 0.042 13.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Flavin_Reduct PF01613.18 EON34083.1 - 2.7e-28 99.0 0.1 3.1e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_3 PF07859.13 EON34084.1 - 1.1e-47 162.6 0.2 1.7e-47 162.1 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EON34084.1 - 2.3e-10 39.9 0.0 3.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EON34084.1 - 0.0021 17.4 0.9 0.0067 15.7 0.9 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON34084.1 - 0.027 14.1 0.3 0.041 13.5 0.3 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EON34084.1 - 0.036 12.9 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.20 EON34084.1 - 0.068 13.3 0.3 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 Thioesterase domain Acyl-CoA_dh_C PF12806.7 EON34085.1 - 2.1e-24 86.0 0.5 4.2e-24 85.1 0.5 1.5 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 EON34085.1 - 1.1e-16 60.8 0.1 2.2e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON34085.1 - 2.9e-16 60.0 0.1 5.3e-15 55.9 0.1 2.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 EON34085.1 - 6.6e-10 38.8 0.2 4.9e-09 36.1 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 EON34085.1 - 0.021 15.1 1.8 0.12 12.6 0.0 2.6 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EON34086.1 - 2.6e-21 76.3 0.4 4.4e-21 75.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON34086.1 - 2.6e-09 37.7 0.2 5.9e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EON34086.1 - 2.3e-05 24.7 0.3 4.6e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 7TMR-HDED PF07697.11 EON34086.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 7TM-HD extracellular Peptidase_S6 PF02395.16 EON34086.1 - 0.35 8.8 0.8 0.5 8.3 0.8 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease Bac_luciferase PF00296.20 EON34087.1 - 2.3e-63 214.5 4.8 3e-63 214.2 4.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase XdhC_C PF13478.6 EON34087.1 - 0.05 14.1 0.1 2.3 8.7 0.0 2.8 2 1 1 3 3 3 0 XdhC Rossmann domain DUF2384 PF09722.10 EON34087.1 - 0.088 12.9 0.4 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) FMO-like PF00743.19 EON34088.1 - 2.2e-19 69.3 0.0 6.2e-18 64.5 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EON34088.1 - 4e-15 55.8 0.0 7.8e-13 48.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34088.1 - 8.2e-14 51.6 0.0 2.5e-11 43.6 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EON34088.1 - 2e-13 50.3 0.0 6.4e-13 48.6 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON34088.1 - 2.7e-13 49.8 1.1 8.1e-12 44.9 0.1 2.6 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EON34088.1 - 2.8e-10 40.3 3.2 9.7e-06 25.4 0.1 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON34088.1 - 1.6e-07 31.8 0.1 0.0067 17.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON34088.1 - 2.4e-05 24.4 0.1 0.024 14.7 0.0 3.6 4 1 0 4 4 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EON34088.1 - 6.1e-05 22.3 0.2 0.00096 18.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EON34088.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EON34088.1 - 0.00075 18.3 0.6 0.0062 15.3 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 EON34088.1 - 0.00078 18.8 0.2 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EON34088.1 - 0.00099 18.3 0.1 0.39 9.8 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EON34088.1 - 0.002 17.3 0.1 0.092 11.8 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EON34088.1 - 0.0034 16.7 1.7 0.0053 16.0 0.0 2.1 2 1 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EON34088.1 - 0.0094 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF364 PF04016.12 EON34088.1 - 0.025 14.2 0.0 0.63 9.6 0.0 2.6 3 0 0 3 3 3 0 Putative heavy-metal chelation ApbA PF02558.16 EON34088.1 - 0.035 13.8 0.7 0.38 10.4 0.1 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EON34088.1 - 0.044 13.8 0.0 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EON34088.1 - 0.099 13.1 0.0 0.87 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding AMP-binding_C PF13193.6 EON34089.1 - 1.1e-17 64.8 0.3 1.3e-17 64.5 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EON34090.1 - 2.5e-12 46.1 0.0 2.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2267 PF10025.9 EON34091.1 - 0.0061 16.8 0.9 0.37 11.1 0.9 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) APH PF01636.23 EON34092.1 - 1.2e-27 97.4 0.7 1.4e-27 97.2 0.7 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EON34092.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EON34092.1 - 0.0086 15.7 0.0 0.041 13.5 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase AMP-binding PF00501.28 EON34093.1 - 7.1e-86 288.4 0.0 9.2e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34093.1 - 6.7e-16 59.0 0.1 1.5e-15 57.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 EON34095.1 - 5e-48 163.6 0.0 6.2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34095.1 - 4.9e-28 98.6 0.0 1.6e-27 96.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EON34095.1 - 0.019 14.9 0.2 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 MaoC_dehydrat_N PF13452.6 EON34095.1 - 0.055 13.6 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase SDH_sah PF01972.16 EON34095.1 - 0.096 11.7 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase adh_short_C2 PF13561.6 EON34096.1 - 1.9e-52 178.2 3.5 3.4e-51 174.0 3.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34096.1 - 1.9e-47 161.3 1.1 2.4e-47 160.9 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34096.1 - 1.4e-14 54.4 0.4 1.1e-13 51.6 0.4 2.0 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 EON34096.1 - 0.013 15.5 0.5 0.023 14.8 0.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 EON34096.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HepII_C PF18675.1 EON34096.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Heparinase II C-terminal domain 2-Hacid_dh_C PF02826.19 EON34096.1 - 0.093 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thiolase_N PF00108.23 EON34097.1 - 7.8e-17 61.5 0.1 7.1e-16 58.3 0.1 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON34097.1 - 1e-09 38.1 0.4 3.4e-08 33.2 0.2 2.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON34097.1 - 7.6e-06 25.7 3.0 0.0004 20.0 0.5 2.3 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EON34097.1 - 0.0016 18.5 0.9 0.98 9.5 0.0 3.5 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 EON34097.1 - 0.0027 17.5 0.6 0.013 15.4 0.2 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 EON34097.1 - 0.0091 14.7 0.1 0.015 14.0 0.1 1.2 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) DSBA PF01323.20 EON34097.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RACo_C_ter PF14574.6 EON34097.1 - 0.11 11.5 0.2 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain MaoC_dehydrat_N PF13452.6 EON34098.1 - 7.1e-32 110.3 0.1 8.5e-32 110.1 0.1 1.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 EON34098.1 - 0.0013 18.3 0.3 0.0026 17.3 0.2 1.6 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydratas PF01575.19 EON34099.1 - 5.1e-17 61.6 0.0 6.3e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EON34099.1 - 0.00024 21.3 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TetR_N PF00440.23 EON34100.1 - 2e-22 78.7 0.5 7e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON34100.1 - 8.5e-10 38.9 4.2 0.00019 21.7 0.2 2.6 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain DprA_WH PF17782.1 EON34100.1 - 0.0053 16.8 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 2 DprA winged helix domain Viral_alk_exo PF01771.17 EON34100.1 - 0.083 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral alkaline exonuclease SUKH-4 PF14435.6 EON34100.1 - 0.9 9.6 4.6 1 9.4 0.0 2.6 2 1 1 3 3 3 0 SUKH-4 immunity protein adh_short_C2 PF13561.6 EON34101.1 - 2e-59 201.0 3.1 2.3e-59 200.8 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34101.1 - 6.3e-48 162.8 2.3 8e-48 162.5 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34101.1 - 1e-09 38.6 3.3 1.7e-09 37.8 3.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON34101.1 - 0.0006 19.4 0.4 0.00077 19.0 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EON34101.1 - 0.0018 18.1 0.5 0.0036 17.2 0.5 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.20 EON34101.1 - 0.0076 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EON34101.1 - 0.017 15.4 0.3 0.032 14.5 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain THF_DHG_CYH_C PF02882.19 EON34101.1 - 0.026 13.8 0.6 0.28 10.5 0.1 2.3 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 EON34101.1 - 0.038 13.1 0.1 0.054 12.6 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 EON34101.1 - 0.11 12.4 0.4 0.17 11.8 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EON34101.1 - 0.49 9.9 8.7 4.1 6.9 0.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase AP_endonuc_2 PF01261.24 EON34102.1 - 3.6e-33 114.8 0.9 5.9e-33 114.1 0.9 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyoxalase_5 PF14696.6 EON34102.1 - 2.5e-09 37.4 0.0 6.9e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 EON34102.1 - 7e-06 26.3 0.0 0.0006 20.0 0.0 2.6 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TetR_C_29 PF17938.1 EON34103.1 - 1.1e-44 151.4 0.3 1.7e-44 150.7 0.3 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON34103.1 - 1.8e-14 53.2 0.3 3.1e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 EON34103.1 - 0.021 15.1 0.1 0.058 13.7 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EON34103.1 - 0.099 12.8 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region DUF3618 PF12277.8 EON34103.1 - 0.14 12.5 6.1 0.3 11.4 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) TetR_C_31 PF17940.1 EON34103.1 - 0.26 11.5 5.2 2.6 8.3 1.0 2.6 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Shikimate_dh_N PF08501.11 EON34104.1 - 1.4e-18 66.9 0.0 2.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Sacchrp_dh_NADP PF03435.18 EON34104.1 - 1.6e-06 28.4 0.2 3.1e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain SDH_C PF18317.1 EON34104.1 - 2.4e-06 27.2 1.1 3.5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EON34104.1 - 2.9e-06 27.4 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EON34104.1 - 1.1e-05 24.9 1.1 1.9e-05 24.2 1.1 1.3 1 0 0 1 1 1 1 ThiF family Ldh_1_N PF00056.23 EON34104.1 - 0.08 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EON34105.1 - 1.8e-29 102.7 45.6 3.4e-19 69.0 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON34105.1 - 7.1e-29 101.0 26.0 5.2e-21 75.0 3.8 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EON34105.1 - 1.7e-14 53.3 12.5 1.7e-14 53.3 12.5 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein IclR PF01614.18 EON34106.1 - 1.5e-26 92.7 0.1 2.5e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EON34106.1 - 6.1e-09 35.6 1.3 1.7e-08 34.1 1.3 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON34106.1 - 0.00047 20.0 2.3 0.0017 18.2 1.0 2.3 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EON34106.1 - 0.0095 15.9 0.7 0.34 10.9 0.1 3.0 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain MarR PF01047.22 EON34106.1 - 0.026 14.5 0.1 0.071 13.1 0.0 1.7 2 0 0 2 2 2 0 MarR family Dioxygenase_C PF00775.21 EON34107.1 - 5.6e-58 195.4 0.1 7e-58 195.1 0.1 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 EON34107.1 - 2.3e-11 43.1 0.7 6.6e-11 41.6 0.7 1.8 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 EON34107.1 - 3.5e-05 24.0 0.1 0.00011 22.3 0.1 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Dioxygenase_C PF00775.21 EON34108.1 - 1.3e-16 60.6 0.0 2.6e-13 49.8 0.0 2.1 1 1 1 2 2 2 2 Dioxygenase CarboxypepD_reg PF13620.6 EON34108.1 - 0.00058 20.1 0.6 0.0019 18.4 0.6 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Flg_new PF09479.10 EON34108.1 - 0.18 12.0 0.2 0.29 11.4 0.2 1.4 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Lyase_1 PF00206.20 EON34109.1 - 1.4e-19 70.6 0.0 2.9e-19 69.6 0.0 1.4 2 0 0 2 2 2 1 Lyase UPF0184 PF03670.13 EON34109.1 - 0.12 12.8 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) CMD PF02627.20 EON34110.1 - 1.2e-26 92.5 0.2 2e-26 91.8 0.2 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Cation_efflux PF01545.21 EON34111.1 - 2.1e-39 135.3 12.2 2.5e-39 135.1 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EON34111.1 - 1.4e-23 82.8 0.8 2.7e-23 81.9 0.8 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4149 PF13664.6 EON34111.1 - 0.025 14.9 1.4 0.078 13.3 0.0 2.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4149) Peptidase_M3 PF01432.20 EON34112.1 - 6.6e-106 355.3 0.0 8.1e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EON34112.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M50B-like GTP_EFTU PF00009.27 EON34113.1 - 4.1e-51 173.3 0.0 6.3e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EON34113.1 - 3.8e-48 162.1 1.1 7.5e-48 161.1 1.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EON34113.1 - 1.1e-22 79.9 0.0 2.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EON34113.1 - 1.9e-06 28.2 3.8 4.6e-06 26.9 3.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON34113.1 - 7e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EON34113.1 - 0.003 17.6 0.0 0.014 15.4 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EON34113.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Abhydrolase_6 PF12697.7 EON34114.1 - 3.2e-11 44.3 6.5 9.9e-09 36.1 3.8 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON34114.1 - 6e-08 32.3 0.9 0.0011 18.3 0.4 3.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON34114.1 - 5.8e-06 26.1 0.1 0.00079 19.1 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EON34114.1 - 6.9e-05 22.7 0.0 0.00043 20.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EON34114.1 - 0.05 13.7 0.0 0.15 12.1 0.1 1.8 2 1 0 2 2 2 0 Thioesterase domain PAF-AH_p_II PF03403.13 EON34114.1 - 0.1 11.1 0.0 2.7 6.4 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 EON34114.1 - 0.17 11.7 0.0 1.1 9.0 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 EON34114.1 - 0.29 10.7 0.0 0.39 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PemK_toxin PF02452.17 EON34115.1 - 4.9e-11 43.0 0.0 5.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system Transglut_core PF01841.19 EON34116.1 - 2.5e-25 89.1 0.1 4.3e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Bact_transglu_N PF08379.10 EON34116.1 - 2.9e-17 63.3 1.9 6.3e-17 62.3 1.9 1.6 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region DUF553 PF04473.12 EON34116.1 - 0.0001 21.9 0.0 0.003 17.1 0.0 2.3 1 1 1 2 2 2 1 Transglutaminase-like domain Transglut_core3 PF13471.6 EON34116.1 - 0.012 15.5 0.6 0.097 12.6 0.3 2.6 1 1 1 2 2 2 0 Transglutaminase-like superfamily Alpha-E PF04168.12 EON34117.1 - 2.6e-74 250.6 4.9 3e-74 250.5 4.9 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. CP_ATPgrasp_2 PF14403.6 EON34118.1 - 5.6e-162 538.9 0.0 7.2e-162 538.6 0.0 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 EON34118.1 - 2.4e-156 519.9 0.0 3.1e-156 519.5 0.0 1.1 1 0 0 1 1 1 1 A circularly permuted ATPgrasp ATPgrasp_YheCD PF14398.6 EON34118.1 - 1.2e-05 24.7 0.0 0.0048 16.2 0.0 2.9 2 1 0 2 2 2 1 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 EON34118.1 - 0.085 12.2 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Ribosomal_S20p PF01649.18 EON34120.1 - 8.4e-26 90.4 15.3 9.3e-26 90.3 15.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 THDPS_N_2 PF14805.6 EON34120.1 - 0.041 14.1 0.8 0.049 13.9 0.8 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DNA_pol3_delta PF06144.13 EON34121.1 - 1.5e-05 24.8 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 EON34121.1 - 0.039 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III AA_permease PF00324.21 EON34122.1 - 4.4e-105 352.0 38.4 5.5e-105 351.7 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EON34122.1 - 2.9e-40 138.4 42.3 3.3e-40 138.2 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease MBA1 PF07961.11 EON34122.1 - 0.087 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 MBA1-like protein PrgI PF12666.7 EON34122.1 - 0.33 11.7 0.2 0.33 11.7 0.2 4.4 5 1 0 5 5 5 0 PrgI family protein Competence PF03772.16 EON34123.1 - 6.5e-51 173.2 19.4 6.5e-51 173.2 19.4 1.8 2 1 0 2 2 2 1 Competence protein HHH_3 PF12836.7 EON34124.1 - 1.2e-20 73.5 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 EON34124.1 - 7.5e-14 50.8 0.1 1.4e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif SLBB PF10531.9 EON34124.1 - 3.4e-11 42.8 0.8 7e-11 41.8 0.3 1.8 2 0 0 2 2 2 1 SLBB domain HHH_5 PF14520.6 EON34124.1 - 5.6e-06 26.9 0.3 3.8e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EON34124.1 - 0.00017 21.6 0.0 0.0095 16.0 0.0 2.3 1 1 1 2 2 2 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 EON34124.1 - 0.0028 17.9 0.0 0.008 16.5 0.0 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family PBP1_TM PF14812.6 EON34124.1 - 0.01 16.2 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal T2SSK PF03934.13 EON34124.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 EON34124.1 - 0.028 14.7 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 EON34124.1 - 0.093 13.1 1.9 0.63 10.5 0.0 2.9 3 0 0 3 3 3 0 IMS family HHH motif HHH_8 PF14716.6 EON34124.1 - 0.094 13.1 0.0 4.1 7.9 0.0 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain DegV PF02645.16 EON34125.1 - 9.3e-67 225.3 0.0 1.1e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Lipase_GDSL_2 PF13472.6 EON34126.1 - 7.7e-13 49.2 0.0 1.1e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family His_Phos_1 PF00300.22 EON34127.1 - 1.2e-55 188.2 0.5 1.5e-55 187.9 0.5 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RsfS PF02410.15 EON34128.1 - 2.4e-24 85.6 0.5 3e-24 85.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CTP_transf_like PF01467.26 EON34129.1 - 1e-28 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like VWA_CoxE PF05762.14 EON34130.1 - 1.6e-46 158.5 0.2 3.2e-46 157.5 0.2 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein AAA_5 PF07728.14 EON34131.1 - 1.8e-12 47.5 0.0 4.9e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EON34131.1 - 1.8e-09 38.1 0.0 5e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EON34131.1 - 1.9e-06 28.1 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EON34131.1 - 6.7e-06 26.6 1.6 3.4e-05 24.3 0.9 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EON34131.1 - 2e-05 24.4 0.0 0.069 13.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON34131.1 - 4.2e-05 23.9 0.1 0.00021 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EON34131.1 - 0.00047 20.1 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 EON34131.1 - 0.00063 19.5 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EON34131.1 - 0.0018 18.0 0.0 0.84 9.3 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 EON34131.1 - 0.0034 17.3 0.3 0.024 14.6 0.0 2.2 2 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EON34131.1 - 0.0063 16.3 0.3 0.021 14.5 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EON34131.1 - 0.012 16.0 1.9 0.12 12.7 0.5 2.7 1 1 1 2 2 2 0 AAA domain AAA_6 PF12774.7 EON34131.1 - 0.018 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 EON34131.1 - 0.018 15.0 0.0 0.17 11.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EON34131.1 - 0.019 15.5 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EON34131.1 - 0.022 14.8 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EON34131.1 - 0.034 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain cpYpsA PF12694.7 EON34131.1 - 0.12 12.1 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family IPT PF01745.16 EON34131.1 - 0.17 11.2 0.0 0.52 9.7 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Aldedh PF00171.22 EON34132.1 - 4.8e-17 61.6 8.5 5e-11 41.8 6.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family MoCF_biosynth PF00994.24 EON34132.1 - 0.05 13.3 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Probable molybdopterin binding domain Trns_repr_metal PF02583.17 EON34133.1 - 1.1e-23 83.4 0.2 1.3e-23 83.2 0.2 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor ACT PF01842.25 EON34133.1 - 0.0068 16.2 0.6 0.7 9.7 0.0 2.6 2 1 1 3 3 3 2 ACT domain MMPL PF03176.15 EON34134.1 - 5.4e-70 235.9 35.2 1.2e-48 165.8 14.4 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 EON34134.1 - 0.0057 16.5 5.7 0.0057 16.5 5.7 3.1 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EON34134.1 - 0.76 7.8 13.2 0.091 10.8 6.0 2.0 2 0 0 2 2 2 0 Patched family DUF302 PF03625.14 EON34135.1 - 9.9e-26 89.4 0.1 1.4e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF302 DSBA PF01323.20 EON34136.1 - 1.4e-06 28.2 0.2 1.5e-05 24.9 0.2 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Multi_Drug_Res PF00893.19 EON34137.1 - 6.9e-22 77.9 9.0 8.8e-22 77.6 9.0 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EON34137.1 - 0.00094 19.4 13.0 0.0011 19.2 13.0 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF1358 PF07096.11 EON34137.1 - 0.0055 16.7 0.6 0.0085 16.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) OST3_OST6 PF04756.13 EON34137.1 - 0.26 10.6 1.8 0.4 10.0 1.8 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF4383 PF14325.6 EON34137.1 - 1.4 9.2 14.6 15 5.9 13.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) DUF4131 PF13567.6 EON34137.1 - 2.2 7.9 11.4 3.1 7.4 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF5381 PF17353.2 EON34137.1 - 4.4 7.0 7.6 1.4 8.6 4.8 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5381) DUF1524 PF07510.11 EON34138.1 - 7.4e-13 48.6 0.0 9.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EON34138.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF4381 PF14316.6 EON34138.1 - 0.0012 19.1 0.4 0.42 10.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) Helicase_C PF00271.31 EON34139.1 - 1.5e-20 73.6 0.0 8.5e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EON34139.1 - 2e-16 60.3 0.1 4.4e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EON34139.1 - 2e-08 34.4 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecG_wedge PF17191.4 EON34139.1 - 4.9e-05 23.0 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 1 RecG wedge domain AAA_30 PF13604.6 EON34139.1 - 0.061 13.0 0.6 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EON34139.1 - 0.078 12.9 0.0 0.61 10.1 0.0 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain SNF2_N PF00176.23 EON34139.1 - 0.084 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain NgoMIV_restric PF09015.10 EON34139.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 NgoMIV restriction enzyme TsaE PF02367.17 EON34139.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dak1_2 PF13684.6 EON34140.1 - 1.5e-70 237.7 0.0 2.2e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Dak2 PF02734.17 EON34140.1 - 2.7e-30 105.5 4.4 7.3e-30 104.1 4.4 1.8 1 0 0 1 1 1 1 DAK2 domain Ribosomal_L28 PF00830.19 EON34141.1 - 3.8e-23 81.4 3.5 4.1e-23 81.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal L28 family ECH_1 PF00378.20 EON34142.1 - 5.2e-42 143.9 0.0 6.5e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34142.1 - 1.7e-21 77.1 0.2 6.2e-21 75.3 0.4 1.6 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase UDG PF03167.19 EON34143.1 - 4.4e-18 65.7 0.0 5.8e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Hexapep PF00132.24 EON34144.1 - 5e-23 79.9 17.9 3.9e-09 35.9 4.4 4.1 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EON34144.1 - 1.2e-14 53.8 14.9 8.7e-09 35.0 2.6 3.7 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EON34144.1 - 0.09 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase AIRS PF00586.24 EON34145.1 - 2e-14 54.0 5.5 5.3e-14 52.7 5.5 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 EON34145.1 - 5.4e-09 36.4 2.6 1e-08 35.5 0.5 2.4 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain AsnC_trans_reg PF01037.21 EON34146.1 - 4.1e-10 39.5 0.2 4.5e-10 39.4 0.2 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain DUF3515 PF12028.8 EON34147.1 - 4.5e-32 111.0 0.0 5.4e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3515) NAD_Gly3P_dh_N PF01210.23 EON34148.1 - 1.5e-50 171.2 0.1 3.1e-50 170.2 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EON34148.1 - 1.6e-48 164.6 1.2 1.6e-48 164.6 1.2 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.16 EON34148.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EON34148.1 - 2.7e-07 31.1 0.3 2.4e-06 28.0 0.0 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EON34148.1 - 0.0015 18.7 0.1 0.026 14.7 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EON34148.1 - 0.018 15.1 0.0 0.052 13.6 0.0 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EON34148.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EON34148.1 - 0.034 14.4 0.0 0.77 10.0 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.6 EON34148.1 - 0.067 13.1 0.9 0.11 12.4 0.1 1.8 2 1 0 2 2 2 0 NAD(P)H-binding DUF2759 PF10958.8 EON34148.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) NTP_transf_3 PF12804.7 EON34149.1 - 5.8e-10 39.7 2.0 8.6e-10 39.2 2.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain CofC PF01983.16 EON34149.1 - 1.4e-06 27.7 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Guanylyl transferase CofC like PP_kinase_C_1 PF17941.1 EON34150.1 - 5.7e-77 257.0 0.0 3.8e-76 254.3 0.0 2.0 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase PF02503.17 EON34150.1 - 5.1e-74 248.2 0.6 7.5e-74 247.7 0.6 1.3 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C PF13090.6 EON34150.1 - 7.4e-54 181.8 0.0 9.9e-53 178.1 0.0 2.4 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase_N PF13089.6 EON34150.1 - 1.1e-34 118.9 0.0 2.7e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 EON34150.1 - 1.2e-11 44.7 0.0 0.00022 21.1 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain NUDIX PF00293.28 EON34151.1 - 4.7e-14 52.6 0.2 9.1e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain His_Phos_1 PF00300.22 EON34151.1 - 5.3e-11 42.6 1.3 3e-09 36.9 0.5 2.5 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) Bac_DNA_binding PF00216.21 EON34152.1 - 2e-26 92.0 1.2 2e-26 92.0 1.2 2.4 2 1 1 3 3 3 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EON34152.1 - 0.0007 19.7 0.1 0.0015 18.7 0.1 1.5 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EON34152.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Borrelia_P83 PF05262.11 EON34152.1 - 0.31 9.5 10.9 0.26 9.7 10.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.15 EON34152.1 - 1.6 7.5 3.6 1.7 7.3 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.10 EON34152.1 - 4.4 6.6 28.9 5.1 6.4 28.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HC2 PF07382.11 EON34152.1 - 5.3 7.1 83.0 1.2 9.2 79.2 1.8 2 1 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Aconitase_C PF00694.19 EON34153.1 - 4.7e-24 85.2 0.0 1.5e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 EON34154.1 - 5.8e-159 530.0 0.0 6.5e-159 529.8 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 EON34154.1 - 0.0036 16.1 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) IclR PF01614.18 EON34155.1 - 1.6e-20 73.2 0.1 1.6e-18 66.8 0.1 2.3 1 1 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EON34155.1 - 4.9e-13 48.7 0.3 1e-12 47.6 0.3 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON34155.1 - 3e-05 23.8 0.2 0.00022 21.0 0.1 2.4 2 0 0 2 2 2 1 MarR family DprA_WH PF17782.1 EON34155.1 - 0.013 15.6 0.1 0.039 14.1 0.1 1.8 1 0 0 1 1 1 0 DprA winged helix domain HTH_5 PF01022.20 EON34155.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Putative_PNPOx PF01243.20 EON34156.1 - 1.3e-19 70.2 0.0 1.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON34156.1 - 1.8e-08 34.5 0.0 2.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EON34156.1 - 2.1e-07 30.6 0.0 3e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like tRNA-synt_1c PF00749.21 EON34157.1 - 1.1e-73 247.9 0.0 1.3e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Abhydrolase_6 PF12697.7 EON34158.1 - 5.5e-23 82.7 1.6 6.9e-23 82.4 1.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON34158.1 - 1.3e-21 77.5 0.0 5.7e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON34158.1 - 3.1e-11 43.0 0.0 4.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EON34158.1 - 0.00027 20.8 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_4 PF08386.10 EON34158.1 - 0.0016 18.6 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 EON34158.1 - 0.0028 16.4 0.0 0.011 14.4 0.0 1.8 2 0 0 2 2 2 1 Ndr family IspD PF01128.19 EON34158.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Peptidase_S15 PF02129.18 EON34158.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAA_hydrolase PF01557.18 EON34159.1 - 3.4e-65 219.7 0.1 4.1e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 EON34159.1 - 8.7e-13 49.0 0.4 2.9e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) MFS_1 PF07690.16 EON34160.1 - 1.6e-43 149.0 75.6 2.8e-36 125.2 42.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EON34160.1 - 0.00082 18.3 12.9 0.00082 18.3 12.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 EON34160.1 - 0.14 10.9 1.3 2.4 6.8 0.1 2.4 2 1 0 3 3 3 0 LacY proton/sugar symporter Iso_dh PF00180.20 EON34161.1 - 1.4e-85 287.5 0.0 1.7e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 2-Hacid_dh_C PF02826.19 EON34162.1 - 1.9e-61 206.6 0.0 2.8e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON34162.1 - 6.2e-36 123.0 0.4 1.2e-35 122.1 0.4 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EON34162.1 - 1.1e-05 25.1 0.5 0.0001 22.0 0.1 2.6 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 EON34162.1 - 4.7e-05 23.6 0.2 0.00042 20.5 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EON34162.1 - 0.0059 16.2 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EON34162.1 - 0.0081 16.7 0.1 0.029 14.9 0.1 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.15 EON34162.1 - 0.039 14.4 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.22 EON34162.1 - 0.074 13.9 0.0 0.5 11.2 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Trypsin PF00089.26 EON34163.1 - 0.0041 17.0 1.3 0.033 14.0 1.1 2.1 1 1 0 1 1 1 1 Trypsin Peptidase_S55 PF05580.12 EON34163.1 - 0.036 14.0 0.6 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 SpoIVB peptidase S55 Trypsin_2 PF13365.6 EON34163.1 - 0.046 14.6 1.3 0.25 12.2 1.3 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain IlvN PF07991.12 EON34164.1 - 8.2e-74 246.7 0.6 1.1e-73 246.2 0.6 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EON34164.1 - 2e-61 206.5 0.2 2.7e-61 206.1 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EON34164.1 - 3.2e-06 27.6 0.1 6.8e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EON34164.1 - 5.6e-06 25.8 0.0 9.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EON34164.1 - 0.00013 22.2 0.1 0.00039 20.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EON34164.1 - 0.0015 18.6 0.0 0.0032 17.6 0.0 1.5 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Nitro_FeMo-Co PF02579.17 EON34164.1 - 0.0025 18.1 0.1 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor ApbA PF02558.16 EON34164.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_N PF05222.15 EON34164.1 - 0.11 12.8 0.1 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain ALS_ss_C PF10369.9 EON34165.1 - 1.6e-27 95.5 1.5 2.1e-27 95.1 0.3 1.7 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EON34165.1 - 1.7e-18 66.1 0.2 4.4e-18 64.8 0.0 1.7 1 1 1 2 2 2 1 ACT domain ACT_5 PF13710.6 EON34165.1 - 2.8e-16 59.1 0.1 1.1e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 EON34165.1 - 1.1e-08 35.6 0.5 2.3e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 EON34165.1 - 0.046 13.7 0.4 0.32 11.0 0.0 2.5 3 1 0 3 3 3 0 ACT domain TPP_enzyme_N PF02776.18 EON34166.1 - 4.2e-52 176.2 2.6 1.4e-51 174.5 1.9 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON34166.1 - 6.2e-51 172.2 0.0 1.9e-50 170.6 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON34166.1 - 1.5e-50 170.5 0.2 2.7e-50 169.7 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EON34166.1 - 0.025 14.3 1.6 0.031 14.0 0.5 1.6 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg bPH_6 PF10756.9 EON34167.1 - 7.2e-16 58.0 1.6 1e-15 57.5 1.6 1.3 1 0 0 1 1 1 1 Bacterial PH domain UbiA PF01040.18 EON34167.1 - 0.02 14.2 4.5 0.027 13.8 4.5 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF2835 PF11197.8 EON34167.1 - 0.051 13.4 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) TDP43_N PF18694.1 EON34167.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain DUF983 PF06170.12 EON34167.1 - 0.75 10.2 5.4 1.2 9.6 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) MgtE PF01769.16 EON34168.1 - 1.5e-26 93.2 6.4 1.5e-26 93.2 6.4 1.8 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 EON34168.1 - 4.1e-22 78.7 0.4 3.6e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 MgtE intracellular N domain CBS PF00571.28 EON34168.1 - 9.1e-18 64.5 1.3 3.1e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain EcsC PF12787.7 EON34168.1 - 0.66 9.6 2.2 1 8.9 2.2 1.3 1 0 0 1 1 1 0 EcsC protein family DUF3325 PF11804.8 EON34168.1 - 2.5 8.3 13.2 2.1 8.6 6.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) ILVD_EDD PF00920.21 EON34169.1 - 1.8e-208 693.4 4.1 2e-208 693.2 4.1 1.0 1 0 0 1 1 1 1 Dehydratase family YjbT PF17089.5 EON34169.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family DoxX PF07681.12 EON34170.1 - 1.6e-15 57.5 10.8 1.6e-15 57.5 10.8 2.2 2 1 1 3 3 3 1 DoxX DoxD PF04173.13 EON34170.1 - 0.068 13.1 1.6 0.11 12.4 1.6 1.3 1 0 0 1 1 1 0 TQO small subunit DoxD UbiA PF01040.18 EON34170.1 - 2 7.7 18.4 0.031 13.6 7.1 2.0 1 1 1 2 2 2 0 UbiA prenyltransferase family SART-1 PF03343.13 EON34170.1 - 4.9 5.6 7.6 6.7 5.1 7.6 1.0 1 0 0 1 1 1 0 SART-1 family GSDH PF07995.11 EON34171.1 - 8.3e-11 41.8 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase GatB_N PF02934.15 EON34172.1 - 7.4e-105 350.2 0.0 1e-104 349.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EON34172.1 - 4.1e-37 127.3 0.0 6.2e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 GatB domain PspC PF04024.12 EON34173.1 - 1.7e-22 79.0 0.8 1.9e-22 78.8 0.8 1.1 1 0 0 1 1 1 1 PspC domain PFK PF00365.20 EON34174.1 - 3.8e-99 331.6 0.2 4.3e-99 331.4 0.2 1.0 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 EON34174.1 - 0.043 13.0 0.1 0.061 12.5 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Response_reg PF00072.24 EON34175.1 - 6e-23 81.2 0.0 9.3e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EON34175.1 - 3.1e-20 71.5 0.0 4.8e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EON34175.1 - 9.2e-08 31.5 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EON34175.1 - 6.1e-07 29.0 0.0 1.5e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 DUF742 PF05331.11 EON34175.1 - 1.2e-05 25.1 1.6 1.5e-05 24.8 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF742) HTH_23 PF13384.6 EON34175.1 - 0.011 15.5 0.1 0.077 12.8 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HisKA_3 PF07730.13 EON34176.1 - 5.9e-18 65.1 2.2 5.9e-18 65.1 2.2 1.8 2 0 0 2 2 2 1 Histidine kinase PGM_PMM_II PF02879.16 EON34176.1 - 0.081 13.5 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Abhydrolase_9 PF10081.9 EON34178.1 - 1.4e-35 122.7 1.4 1.2e-24 86.9 0.3 2.2 1 1 1 2 2 2 2 Alpha/beta-hydrolase family Abhydrolase_9_N PF15420.6 EON34178.1 - 4.8e-06 26.7 10.1 4.8e-06 26.7 10.1 2.2 2 1 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus Hydrolase_4 PF12146.8 EON34178.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4223 PF13978.6 EON34178.1 - 0.11 12.5 0.9 1.4 9.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) Amidase PF01425.21 EON34179.1 - 4e-153 510.6 0.5 4.6e-153 510.4 0.5 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 EON34180.1 - 1.7e-15 57.0 0.1 2.3e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit ACT PF01842.25 EON34181.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 ACT domain ACT_4 PF13291.6 EON34181.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 ACT domain Macro PF01661.21 EON34182.1 - 5.2e-39 133.0 0.0 6.3e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Macro domain DNA_ligase_aden PF01653.18 EON34183.1 - 8.9e-121 402.8 0.0 1.1e-120 402.5 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 EON34183.1 - 7.5e-32 109.1 2.1 1.5e-31 108.1 2.1 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 EON34183.1 - 8.7e-21 73.8 0.0 1.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif BRCT PF00533.26 EON34183.1 - 1.4e-10 41.4 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 EON34183.1 - 6.8e-10 39.4 0.2 3.7e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_ligase_ZBD PF03119.16 EON34183.1 - 8.4e-07 28.9 5.5 2.3e-06 27.5 5.5 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain PTCB-BRCT PF12738.7 EON34183.1 - 2.7e-05 24.0 0.0 6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 EON34183.1 - 0.0012 18.5 0.0 0.0043 16.9 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif YjbR PF04237.13 EON34184.1 - 3.2e-15 56.5 0.0 3.9e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 YjbR Meth_synt_2 PF01717.18 EON34185.1 - 7e-22 78.1 0.0 8.7e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain tRNA_Me_trans PF03054.16 EON34186.1 - 9.6e-111 370.0 0.0 1.1e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EON34186.1 - 0.00055 19.6 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 EON34186.1 - 0.032 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 EON34186.1 - 0.058 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 EON34186.1 - 0.08 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD synthase Aminotran_5 PF00266.19 EON34187.1 - 2.1e-66 224.4 0.0 2.7e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EON34187.1 - 5.9e-09 35.6 0.0 6.8e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EON34187.1 - 0.06 12.6 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4334 PF14232.6 EON34188.1 - 1.2e-28 98.8 0.2 3e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 EON34188.1 - 4e-24 84.4 0.2 6.7e-24 83.7 0.2 1.4 1 0 0 1 1 1 1 GXWXG protein Acyltransferase PF01553.21 EON34189.1 - 2.1e-18 66.2 0.0 3.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acetyltransf_5 PF13444.6 EON34190.1 - 1.9e-27 95.9 0.0 3.2e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 EON34190.1 - 0.049 13.2 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Autoinducer synthase ETF_alpha PF00766.19 EON34191.1 - 1.1e-35 121.5 2.0 2.4e-35 120.4 2.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 EON34191.1 - 5.7e-29 101.3 6.8 1e-28 100.5 6.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF PF01012.21 EON34192.1 - 1.5e-42 145.6 4.2 1.9e-42 145.2 4.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Methyltransf_11 PF08241.12 EON34193.1 - 1.7e-21 76.7 0.1 3.1e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON34193.1 - 5.4e-19 68.7 0.1 9.8e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON34193.1 - 1.7e-12 47.4 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON34193.1 - 3.1e-12 47.1 0.0 5.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON34193.1 - 1.9e-11 44.1 0.0 2.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EON34193.1 - 0.00023 21.1 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EON34193.1 - 0.00042 19.9 0.0 0.00094 18.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EON34193.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EON34193.1 - 0.002 18.2 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EON34193.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 EON34193.1 - 0.018 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme CMAS PF02353.20 EON34193.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EON34193.1 - 0.056 14.5 0.2 0.24 12.4 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EON34193.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1957 PF09210.11 EON34194.1 - 4.4e-24 84.8 0.8 7.8e-24 84.0 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1957) Glyco_hydro_57 PF03065.15 EON34194.1 - 3.1e-19 69.3 0.0 8.2e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Glycos_transf_1 PF00534.20 EON34195.1 - 9.1e-37 126.2 0.0 1.4e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON34195.1 - 4.8e-30 104.8 8.5 2.8e-29 102.3 6.9 2.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EON34195.1 - 5.6e-27 94.8 0.2 1.2e-26 93.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON34195.1 - 8.4e-25 88.1 10.0 8.4e-25 88.1 10.0 3.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EON34195.1 - 5.3e-24 85.3 1.4 5.3e-24 85.3 1.4 2.3 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 EON34195.1 - 5.4e-13 49.1 0.1 1.8e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF4113 PF13438.6 EON34195.1 - 0.03 14.4 0.3 0.7 10.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Glyco_trans_4_2 PF13477.6 EON34195.1 - 0.14 12.2 0.5 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glycogen_syn PF05693.13 EON34195.1 - 0.22 10.0 0.2 0.87 8.1 0.0 1.8 2 0 0 2 2 2 0 Glycogen synthase Epimerase PF01370.21 EON34195.1 - 1.1 8.7 3.0 8.6 5.7 0.2 2.8 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Hexapep PF00132.24 EON34196.1 - 2.1e-09 36.7 11.0 7.7e-07 28.6 0.8 4.5 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EON34196.1 - 0.53 10.1 7.4 0.85 9.4 1.3 3.5 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase PQQ_3 PF13570.6 EON34197.1 - 3e-09 37.1 14.0 2.9e-05 24.4 0.6 5.3 5 0 0 5 5 5 3 PQQ-like domain PQQ_2 PF13360.6 EON34197.1 - 4.9e-09 36.1 15.6 7.6e-06 25.7 4.9 3.1 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 EON34197.1 - 3.6e-06 26.6 0.6 0.00014 21.6 0.1 3.8 5 0 0 5 5 5 1 PQQ enzyme repeat RHS_repeat PF05593.14 EON34197.1 - 0.17 12.5 1.2 1.1 9.8 0.0 2.8 2 0 0 2 2 2 0 RHS Repeat KAP_NTPase PF07693.14 EON34198.1 - 1.2e-39 136.4 0.0 2e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 EON34198.1 - 6.3e-08 33.2 0.2 2e-07 31.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON34198.1 - 0.00014 22.1 0.6 0.008 16.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EON34198.1 - 0.025 14.5 0.0 0.065 13.1 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EON34198.1 - 0.04 13.6 0.1 0.23 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON34198.1 - 0.076 13.5 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 EON34198.1 - 0.086 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EON34198.1 - 0.1 13.0 0.0 9.1 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON34198.1 - 0.16 11.9 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Thump_like PF18096.1 EON34199.1 - 3.7e-21 74.8 0.6 7.9e-21 73.8 0.2 1.9 2 0 0 2 2 2 1 THUMP domain-like Methyltransf_11 PF08241.12 EON34201.1 - 6.1e-25 87.7 0.0 1.3e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON34201.1 - 3.2e-22 79.0 0.1 8.6e-22 77.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON34201.1 - 1.6e-20 73.5 0.0 3.8e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON34201.1 - 4.8e-15 56.1 0.1 1.6e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON34201.1 - 6.6e-15 55.3 0.0 1.3e-14 54.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON34201.1 - 4.3e-14 52.4 0.0 6.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EON34201.1 - 9.4e-06 25.3 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 EON34201.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 EON34201.1 - 9.5e-05 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EON34201.1 - 0.00073 18.2 0.0 0.00096 17.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EON34201.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EON34201.1 - 0.0031 17.0 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N_2 PF13602.6 EON34201.1 - 0.043 14.9 0.0 0.086 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ECH_1 PF00378.20 EON34202.1 - 2.7e-59 200.5 0.1 3.2e-59 200.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34202.1 - 1e-25 90.9 0.3 1.2e-25 90.7 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EON34202.1 - 0.07 13.1 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DNA_primase_S PF01896.19 EON34203.1 - 1.2e-07 31.9 0.0 3.9e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 DNA primase small subunit MarR_2 PF12802.7 EON34204.1 - 4.1e-15 55.4 2.7 4.7e-14 52.0 0.3 2.5 1 1 1 2 2 2 1 MarR family MarR PF01047.22 EON34204.1 - 5.4e-12 45.5 0.0 2.1e-11 43.6 0.0 2.0 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 EON34204.1 - 6.9e-11 42.5 0.3 1.5e-09 38.2 0.1 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain DprA_WH PF17782.1 EON34204.1 - 5.5e-06 26.4 1.8 1.9e-05 24.7 0.7 2.1 1 1 1 2 2 2 1 DprA winged helix domain HTH_IclR PF09339.10 EON34204.1 - 6.3e-06 25.9 0.1 6.3e-06 25.9 0.1 2.7 4 0 0 4 4 4 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EON34204.1 - 2.4e-05 24.3 2.0 0.00017 21.6 0.0 2.8 3 1 0 3 3 3 1 Helix-turn-helix domain TrmB PF01978.19 EON34204.1 - 0.0063 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 EON34204.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Replic_Relax PF13814.6 EON34204.1 - 0.031 14.4 1.0 0.43 10.6 1.0 2.1 1 1 0 1 1 1 0 Replication-relaxation HTH_Crp_2 PF13545.6 EON34204.1 - 0.033 14.2 0.2 0.11 12.4 0.1 2.1 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain LacI PF00356.21 EON34204.1 - 0.04 13.7 0.4 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_24 PF13412.6 EON34204.1 - 0.05 13.2 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 EON34204.1 - 0.14 12.6 0.0 0.91 9.9 0.0 2.1 1 1 1 2 2 2 0 Transcriptional regulator HTH_11 PF08279.12 EON34204.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain MDMPI_N PF11716.8 EON34205.1 - 8.3e-11 42.7 8.7 1.1e-09 39.1 2.7 2.3 1 1 1 2 2 2 2 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON34205.1 - 0.024 15.1 1.3 0.039 14.5 1.2 1.5 1 1 0 1 1 1 0 DinB superfamily NUDIX PF00293.28 EON34206.1 - 1.1e-06 28.7 2.1 7.1e-05 22.9 2.1 2.8 1 1 0 1 1 1 1 NUDIX domain ABC_tran PF00005.27 EON34207.1 - 1.9e-24 86.7 0.0 2.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34207.1 - 2.4e-08 34.1 2.0 0.0033 17.3 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON34207.1 - 0.0022 18.4 0.2 0.0083 16.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON34207.1 - 0.0043 17.3 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EON34207.1 - 0.0043 17.6 0.0 0.0069 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON34207.1 - 0.0062 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 EON34207.1 - 0.033 11.7 0.0 0.044 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_15 PF13175.6 EON34207.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EON34207.1 - 0.058 13.1 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EON34207.1 - 0.068 12.6 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EON34207.1 - 0.083 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EON34207.1 - 0.12 11.9 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EON34207.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EON34207.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 EON34207.1 - 0.35 9.4 0.0 0.64 8.6 0.0 1.3 2 0 0 2 2 2 0 AAA domain Bac_luciferase PF00296.20 EON34208.1 - 7.8e-41 140.5 8.2 1.3e-40 139.7 8.2 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Cupin_5 PF06172.11 EON34209.1 - 1.1e-47 161.7 0.0 1.3e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) PTH2 PF01981.16 EON34210.1 - 5.4e-11 42.8 0.4 2e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 HAD PF12710.7 EON34211.1 - 1.3e-23 84.4 0.6 2.3e-23 83.6 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 EON34211.1 - 1.8e-19 69.5 1.9 4.8e-19 68.1 0.6 2.3 2 0 0 2 2 2 1 ACT domain Hydrolase PF00702.26 EON34211.1 - 2.9e-18 66.9 2.5 3.6e-18 66.6 1.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON34211.1 - 1.3e-13 51.3 0.2 6e-13 49.1 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EON34211.1 - 3e-05 23.7 0.0 0.00044 19.9 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 EON34211.1 - 3.8e-05 23.8 0.0 0.0012 19.0 0.0 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EON34211.1 - 0.00031 20.2 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 Putative Phosphatase ACT PF01842.25 EON34211.1 - 0.0064 16.2 0.8 2.4 8.0 0.2 2.8 2 0 0 2 2 2 2 ACT domain COX1 PF00115.20 EON34212.1 - 1.5e-147 492.0 68.6 1.7e-147 491.8 68.6 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Peripla_BP_2 PF01497.18 EON34213.1 - 6.9e-10 38.9 0.2 1.1e-09 38.2 0.2 1.3 1 1 0 1 1 1 1 Periplasmic binding protein Pro_CA PF00484.19 EON34214.1 - 2.1e-13 50.8 0.1 7.2e-12 45.9 0.1 2.0 1 1 0 1 1 1 1 Carbonic anhydrase SNF2_N PF00176.23 EON34216.1 - 7.5e-56 189.3 0.0 1.4e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3670 PF12419.8 EON34216.1 - 3.8e-21 75.4 0.8 1.4e-20 73.6 0.3 2.2 2 0 0 2 2 2 1 SNF2 Helicase protein Helicase_C PF00271.31 EON34216.1 - 3.9e-14 52.9 0.0 8.5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EON34216.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SWIM PF04434.17 EON34217.1 - 0.001 18.7 0.4 0.0017 17.9 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger Ribonuc_red_sm PF00268.21 EON34218.1 - 2.1e-90 303.0 0.0 2.4e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF2247 PF10004.9 EON34218.1 - 0.024 14.4 0.2 0.11 12.2 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Ribonuc_red_lgC PF02867.15 EON34219.1 - 3.7e-144 481.2 0.4 6.3e-142 473.8 0.3 2.7 2 1 0 2 2 2 1 Ribonucleotide reductase, barrel domain RNR_N PF08343.10 EON34219.1 - 5.2e-29 100.1 7.9 1.1e-28 99.1 6.3 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase N-terminal Ribonuc_red_lgN PF00317.21 EON34219.1 - 2.5e-11 43.4 0.1 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Fib_succ_major PF09603.10 EON34219.1 - 0.14 12.8 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) Flavodoxin_NdrI PF07972.11 EON34220.1 - 9.2e-48 161.4 0.0 1.1e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 NrdI Flavodoxin like Glutaredoxin PF00462.24 EON34221.1 - 2.4e-15 56.5 0.0 2.8e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EON34221.1 - 0.0027 18.1 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N PF02798.20 EON34221.1 - 0.0077 16.5 0.0 0.0092 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 EON34221.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain SH3BGR PF04908.15 EON34221.1 - 0.091 12.9 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 EON34221.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FMN_red PF03358.15 EON34222.1 - 1e-33 116.3 0.1 1.3e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EON34222.1 - 2.4e-06 27.4 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold TetR_N PF00440.23 EON34223.1 - 8.4e-15 54.3 1.4 1.1e-14 53.9 0.6 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 EON34223.1 - 0.011 15.8 1.1 2.1 8.5 0.0 3.3 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EON34223.1 - 0.076 12.4 1.1 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 SAM_Exu PF18609.1 EON34223.1 - 0.13 12.4 0.1 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Exuperantia SAM-like domain FAD_binding_3 PF01494.19 EON34224.1 - 7.6e-22 78.0 0.1 1e-21 77.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON34224.1 - 3.3e-06 26.6 1.7 0.00018 20.8 0.5 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34224.1 - 7.9e-06 26.0 0.4 2e-05 24.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EON34224.1 - 0.00063 18.9 0.4 0.001 18.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EON34224.1 - 0.0018 17.5 1.2 0.0026 16.9 1.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EON34224.1 - 0.031 13.6 0.1 0.37 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EON34224.1 - 0.038 14.0 1.4 4.2 7.4 0.1 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EON34224.1 - 0.045 13.0 0.3 0.078 12.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EON34224.1 - 0.047 12.9 0.2 0.92 8.7 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON34224.1 - 0.066 11.9 0.6 0.2 10.3 0.6 1.8 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EON34224.1 - 0.11 13.1 1.6 0.23 12.0 0.2 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase T7SS_ESX1_EccB PF05108.13 EON34225.1 - 6e-172 572.6 1.4 6.8e-172 572.4 1.4 1.0 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B EccE PF11203.8 EON34226.1 - 2.9e-17 62.8 6.5 2.9e-17 62.8 6.5 2.6 2 1 0 3 3 3 1 Putative type VII ESX secretion system translocon, EccE PMI_typeI PF01238.21 EON34227.1 - 1.5e-59 202.1 0.0 4.6e-59 200.5 0.0 1.7 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EON34227.1 - 0.017 14.8 0.0 0.78 9.5 0.0 2.5 2 0 0 2 2 2 0 Cupin domain bact-PGI_C PF10432.9 EON34228.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain DUF3499 PF12005.8 EON34229.1 - 3.7e-37 127.7 0.3 1.4e-36 125.8 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3499) Zincin_1 PF06262.11 EON34230.1 - 2.7e-12 46.6 0.2 5.3e-12 45.7 0.1 1.4 1 1 0 1 1 1 1 Zincin-like metallopeptidase Whib PF02467.16 EON34231.1 - 2.4e-27 95.3 2.4 3.3e-27 94.8 2.4 1.2 1 0 0 1 1 1 1 Transcription factor WhiB UPF0052 PF01933.18 EON34232.1 - 9e-63 212.2 0.0 1.1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 AIMP2_LysRS_bd PF16780.5 EON34232.1 - 0.032 13.9 0.1 0.094 12.5 0.1 1.8 2 0 0 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain F420_ligase PF01996.16 EON34233.1 - 2.3e-41 141.8 1.0 4.7e-34 117.8 0.4 2.2 1 1 1 2 2 2 2 F420-0:Gamma-glutamyl ligase Nitroreductase PF00881.24 EON34233.1 - 8e-27 94.3 0.0 2.1e-26 93.0 0.0 1.7 2 0 0 2 2 2 1 Nitroreductase family TM1586_NiRdase PF14512.6 EON34233.1 - 0.0056 16.3 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase NUDIX PF00293.28 EON34234.1 - 7.7e-11 42.2 0.0 1.6e-10 41.1 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain NTP_transferase PF00483.23 EON34235.1 - 2e-71 240.5 0.0 2.7e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON34235.1 - 7.3e-09 36.2 0.0 1.9e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EON34235.1 - 0.00069 19.2 11.6 0.0073 16.0 2.7 3.8 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EON34235.1 - 0.0033 16.4 0.1 0.0068 15.4 0.1 1.5 1 0 0 1 1 1 1 L-fucokinase Glyco_transf_4 PF13439.6 EON34236.1 - 3.7e-33 114.9 3.0 3.9e-33 114.8 1.8 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EON34236.1 - 3.3e-28 98.3 0.0 6e-28 97.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EON34236.1 - 3.8e-24 85.6 1.2 6.6e-24 84.9 0.2 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EON34236.1 - 2.7e-19 70.2 15.9 3.8e-19 69.7 10.9 2.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EON34236.1 - 1.5e-11 44.4 0.4 1.2e-09 38.2 0.1 2.2 1 1 1 2 2 2 2 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 EON34236.1 - 1.9e-10 41.0 0.0 5.3e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 EON34236.1 - 0.044 13.5 1.6 0.87 9.3 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) DUF5612 PF18462.1 EON34236.1 - 0.055 13.3 1.3 0.97 9.2 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) Methyltransf_25 PF13649.6 EON34237.1 - 0.012 16.3 0.0 0.035 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EON34237.1 - 0.018 15.6 0.1 0.08 13.6 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EON34237.1 - 0.11 12.3 0.0 7.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Trm112p PF03966.16 EON34237.1 - 0.17 12.5 0.0 0.46 11.1 0.0 1.8 2 0 0 2 2 2 0 Trm112p-like protein DUF3117 PF11314.8 EON34238.1 - 8.4e-28 95.9 4.1 9.2e-28 95.8 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3117) DivIVA PF05103.13 EON34239.1 - 0.0011 19.0 0.0 0.0015 18.7 0.0 1.1 1 0 0 1 1 1 1 DivIVA protein DUF4083 PF13314.6 EON34239.1 - 5.9 6.9 5.3 8.5 6.4 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Glycos_transf_2 PF00535.26 EON34240.1 - 2e-13 50.5 0.0 5e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON34240.1 - 1.4e-06 28.4 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON34240.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Osmo_MPGsynth PF09488.10 EON34240.1 - 0.097 11.3 0.1 4.1 6.0 0.0 2.6 2 1 1 3 3 3 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Glyco_tranf_2_4 PF13704.6 EON34240.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pterin_bind PF00809.22 EON34241.1 - 2.6e-67 227.1 1.6 3.6e-67 226.6 1.6 1.2 1 0 0 1 1 1 1 Pterin binding enzyme AMP-binding PF00501.28 EON34242.1 - 3.2e-64 217.1 0.0 3.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34242.1 - 8.7e-07 29.8 0.0 1.8e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lysine_decarbox PF03641.14 EON34243.1 - 4.6e-35 120.6 0.0 5.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EON34243.1 - 2.8e-17 62.7 0.0 3.3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 EON34243.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A Lysine_decarbox PF03641.14 EON34244.1 - 9e-35 119.6 0.0 1.4e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EON34244.1 - 1.5e-15 57.2 0.0 2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family Peptidase_M20 PF01546.28 EON34245.1 - 1.3e-18 67.5 0.5 2.1e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON34245.1 - 8.1e-12 45.0 0.0 2.7e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON34245.1 - 7.7e-06 25.7 0.0 0.00035 20.3 0.1 2.2 2 0 0 2 2 2 1 Peptidase family M28 DM13 PF10517.9 EON34246.1 - 3.5e-26 91.8 0.0 4.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Electron transfer DM13 THDPS_M PF14789.6 EON34247.1 - 3.3e-21 75.1 0.1 6.2e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase middle Hexapep_2 PF14602.6 EON34247.1 - 4e-14 52.1 2.2 4e-14 52.1 2.2 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EON34247.1 - 0.045 13.5 9.2 3 7.7 0.9 4.3 3 2 0 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF3072 PF11272.8 EON34248.1 - 3.6e-30 103.6 2.1 4.6e-30 103.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3072) Aminotran_1_2 PF00155.21 EON34249.1 - 2.8e-37 128.7 0.0 8.2e-37 127.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EON34249.1 - 0.023 14.0 0.1 0.048 13.0 0.1 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fer4 PF00037.27 EON34250.1 - 3.2e-10 39.4 18.2 3.7e-08 32.9 5.3 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EON34250.1 - 1.2e-06 29.3 1.8 0.00041 21.2 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EON34250.1 - 3.9e-06 26.9 4.7 0.0001 22.4 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EON34250.1 - 2.4e-05 24.8 13.5 0.00015 22.3 12.5 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON34250.1 - 6.7e-05 22.8 5.0 6.7e-05 22.8 5.0 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 EON34250.1 - 0.00018 21.6 9.9 0.00043 20.4 9.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EON34250.1 - 0.00023 21.6 4.5 0.0021 18.5 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON34250.1 - 0.00035 20.8 2.3 0.00035 20.8 2.3 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 EON34250.1 - 0.0024 17.8 3.4 0.0024 17.8 3.4 2.8 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 EON34250.1 - 0.0053 16.9 16.1 0.047 13.8 16.1 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EON34250.1 - 0.021 15.4 13.3 0.08 13.5 3.0 2.2 1 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_11 PF13247.6 EON34250.1 - 0.087 13.0 5.4 0.14 12.3 5.4 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EON34250.1 - 0.19 12.8 18.7 0.25 12.4 7.1 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EON34250.1 - 0.49 11.0 11.6 0.5 10.9 3.6 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CDO_I PF05995.12 EON34251.1 - 1.1e-14 54.1 3.5 2.6e-11 43.1 0.3 2.1 2 0 0 2 2 2 2 Cysteine dioxygenase type I Cupin_2 PF07883.11 EON34251.1 - 0.00074 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 EON34251.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein PCO_ADO PF07847.12 EON34251.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PCO_ADO Rhodanese PF00581.20 EON34252.1 - 1.9e-05 25.1 0.0 2.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain SRCR_2 PF15494.6 EON34252.1 - 0.03 14.8 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Radical_SAM PF04055.21 EON34253.1 - 5.9e-10 39.8 0.0 1.3e-09 38.7 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Pyr_redox_2 PF07992.14 EON34254.1 - 6.6e-15 55.1 0.0 4.6e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON34254.1 - 4.2e-12 45.9 0.0 8.3e-08 31.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EON34254.1 - 4.8e-12 45.7 0.0 6.9e-11 42.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34254.1 - 2.4e-11 43.7 0.3 9.9e-11 41.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EON34254.1 - 7.9e-10 37.8 0.0 2.7e-08 32.7 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 EON34254.1 - 3.2e-08 33.5 7.0 9.1e-07 28.8 1.2 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON34254.1 - 3.4e-05 23.1 1.5 4.3e-05 22.8 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EON34254.1 - 3.7e-05 23.8 0.4 0.0037 17.3 0.1 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EON34254.1 - 0.00017 21.6 0.1 0.68 10.0 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EON34254.1 - 0.00057 19.2 0.1 0.0014 18.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EON34254.1 - 0.00077 18.6 0.7 0.0055 15.8 0.1 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EON34254.1 - 0.0012 18.3 0.1 0.0041 16.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EON34254.1 - 0.0014 17.9 1.5 0.0066 15.7 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EON34254.1 - 0.0022 18.5 3.0 0.012 16.2 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EON34254.1 - 0.012 14.7 0.3 0.023 13.8 0.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EON34254.1 - 0.03 13.1 0.9 0.067 11.9 0.9 1.5 1 0 0 1 1 1 0 HI0933-like protein Pro_Al_protease PF02983.14 EON34254.1 - 0.038 14.1 0.1 0.21 11.7 0.1 2.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Type_III_YscX PF09474.10 EON34254.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) F420_oxidored PF03807.17 EON34254.1 - 0.17 12.5 0.2 2.6 8.7 0.1 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 2TM PF13239.6 EON34256.1 - 0.37 11.1 1.7 0.86 10.0 1.7 1.6 1 0 0 1 1 1 0 2TM domain PIG-L PF02585.17 EON34257.1 - 2.2e-21 76.9 0.0 3.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF3931 PF13082.6 EON34257.1 - 0.23 11.6 1.2 0.81 9.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3931) SBP_bac_5 PF00496.22 EON34258.1 - 7.3e-30 104.2 0.0 3.8e-26 91.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle GTP_EFTU PF00009.27 EON34259.1 - 4e-52 176.6 0.0 6.3e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EON34259.1 - 1.8e-23 82.4 0.0 3.9e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EON34259.1 - 1.6e-10 41.2 0.1 4.6e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON34259.1 - 3.1e-06 27.2 0.0 7.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EON34259.1 - 0.0033 16.8 0.1 0.0054 16.1 0.1 1.2 1 0 0 1 1 1 1 Septin EamA PF00892.20 EON34261.1 - 9e-15 55.1 32.6 4.8e-12 46.2 11.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family ABC_tran PF00005.27 EON34262.1 - 9.1e-30 104.0 0.0 1.5e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34262.1 - 2.8e-06 27.4 0.1 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34262.1 - 4.7e-06 26.2 0.1 0.07 12.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON34262.1 - 7.6e-05 22.4 0.2 0.00022 20.9 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON34262.1 - 0.001 19.6 0.2 0.0015 19.1 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EON34262.1 - 0.0016 18.8 1.0 0.0048 17.3 1.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON34262.1 - 0.0038 17.2 0.2 0.0083 16.0 0.1 1.5 2 0 0 2 2 1 1 RsgA GTPase AAA PF00004.29 EON34262.1 - 0.0074 16.7 0.0 0.037 14.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EON34262.1 - 0.012 15.9 0.0 0.023 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EON34262.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase OB_aCoA_assoc PF01796.17 EON34262.1 - 0.018 15.0 0.7 0.018 15.0 0.7 2.4 2 1 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated AAA_22 PF13401.6 EON34262.1 - 0.019 15.3 0.2 0.068 13.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EON34262.1 - 0.02 15.1 0.3 0.26 11.6 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 EON34262.1 - 0.029 13.2 0.6 1.9 7.2 0.2 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class ATPase_2 PF01637.18 EON34262.1 - 0.038 13.9 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 EON34262.1 - 0.05 12.4 0.1 0.074 11.8 0.1 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 EON34262.1 - 0.056 13.4 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 EON34262.1 - 0.056 12.6 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EON34262.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EON34262.1 - 0.14 12.3 0.7 0.63 10.2 0.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON34262.1 - 0.15 11.8 3.0 0.3 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EON34262.1 - 0.25 11.1 0.1 0.39 10.4 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BPD_transp_1 PF00528.22 EON34263.1 - 3.6e-14 52.9 58.1 6.2e-09 35.9 20.8 3.9 3 1 1 4 4 4 2 Binding-protein-dependent transport system inner membrane component PLDc_3 PF13918.6 EON34263.1 - 0.19 11.4 0.2 0.33 10.6 0.2 1.3 1 0 0 1 1 1 0 PLD-like domain SBP_bac_6 PF13343.6 EON34264.1 - 8.3e-17 61.4 0.0 2.2e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EON34264.1 - 2.1e-12 47.3 0.3 3.7e-12 46.5 0.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EON34264.1 - 1.5e-06 28.4 0.9 1.6e-05 25.0 0.9 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EON34264.1 - 8.1e-06 25.8 0.1 0.00089 19.2 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SfLAP PF11139.8 EON34266.1 - 2.4e-48 164.4 28.7 2.7e-48 164.3 28.7 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein Halogen_Hydrol PF10112.9 EON34266.1 - 0.9 9.5 3.5 0.32 11.0 0.5 1.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LIP PF03583.14 EON34268.1 - 5.5e-07 29.2 0.7 8.7e-07 28.5 0.7 1.2 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 EON34268.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 YhhN PF07947.14 EON34269.1 - 1.3e-25 90.1 0.1 1.7e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 YhhN family HhH-GPD PF00730.25 EON34271.1 - 4.7e-14 52.7 0.0 7.7e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HNH PF01844.23 EON34273.1 - 0.0095 16.1 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EON34274.1 - 1.2e-10 41.4 4.7 1.8e-10 40.9 4.7 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 EON34274.1 - 0.0012 18.9 1.9 0.0068 16.5 1.9 2.0 1 1 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EON34274.1 - 0.0015 18.3 0.7 0.0025 17.7 0.7 1.3 1 0 0 1 1 1 1 HNH endonuclease Toxin_8 PF07365.12 EON34274.1 - 0.065 13.4 0.4 0.11 12.7 0.4 1.4 1 0 0 1 1 1 0 Alpha conotoxin precursor HNH_5 PF14279.6 EON34275.1 - 2.2e-06 27.4 1.7 1.2e-05 25.1 1.7 2.0 1 1 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EON34275.1 - 0.0023 18.1 0.5 0.0037 17.4 0.5 1.4 1 0 0 1 1 1 1 HNH endonuclease TetR_N PF00440.23 EON34276.1 - 5.1e-09 35.8 1.6 7.9e-09 35.2 0.2 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Nbl1_Borealin_N PF10444.9 EON34276.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Thymidylat_synt PF00303.19 EON34278.1 - 5.1e-122 406.2 0.0 5.7e-122 406.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 EON34279.1 - 2.4e-49 167.1 0.0 2.7e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase HTH_42 PF06224.12 EON34280.1 - 7.2e-68 229.5 22.1 9.5e-68 229.1 22.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Hydrolase_3 PF08282.12 EON34281.1 - 1.8e-09 37.7 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.13 EON34281.1 - 2.3e-08 34.1 0.0 3.3e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Phage_endo_I PF05367.11 EON34281.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Phage endonuclease I PhoD PF09423.10 EON34282.1 - 1.4e-117 392.6 0.0 1.7e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EON34282.1 - 1.7e-30 105.4 1.6 1.9e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EON34282.1 - 0.0004 20.9 0.2 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EON34282.1 - 0.029 14.9 0.0 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EON34282.1 - 0.088 13.7 0.4 0.28 12.1 0.4 1.8 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C fn3 PF00041.21 EON34282.1 - 0.12 12.7 0.0 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 Fibronectin type III domain TAT_signal PF10518.9 EON34282.1 - 7.7 6.5 14.0 0.087 12.7 3.6 3.1 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Thy1 PF02511.15 EON34283.1 - 3.9e-56 189.8 0.3 4.7e-56 189.6 0.3 1.0 1 0 0 1 1 1 1 Thymidylate synthase complementing protein AphA_like PF14557.6 EON34283.1 - 0.035 13.8 0.0 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator DHDPS PF00701.22 EON34284.1 - 1.2e-73 247.4 0.0 1.3e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF218 PF02698.17 EON34284.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain Lactamase_B_2 PF12706.7 EON34285.1 - 2.5e-13 50.0 0.4 2e-12 47.1 0.1 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EON34285.1 - 3e-13 50.2 1.7 1.1e-12 48.4 1.7 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RNase_J_C PF17770.1 EON34285.1 - 2.4e-12 47.7 0.0 4.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain RMMBL PF07521.12 EON34285.1 - 2.4e-10 40.2 0.0 1.6e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 EON34285.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EON34285.1 - 0.097 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MDMPI_N PF11716.8 EON34286.1 - 1.5e-08 35.4 5.6 1e-07 32.7 3.5 2.4 1 1 1 2 2 2 2 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 EON34286.1 - 0.0013 19.6 5.7 0.0013 19.6 5.7 2.5 2 1 0 2 2 2 1 MDMPI C-terminal domain FtsK_SpoIIIE PF01580.18 EON34288.1 - 2.4e-66 223.6 0.3 2.2e-64 217.2 0.3 2.2 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_alpha PF17854.1 EON34288.1 - 1.7e-26 92.3 0.0 3.1e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 EON34288.1 - 5.8e-23 80.5 0.0 1.4e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Ftsk gamma domain DUF87 PF01935.17 EON34288.1 - 5.9e-06 26.5 0.0 1.5e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_4TM PF13491.6 EON34288.1 - 6.1e-06 26.0 13.8 9.8e-06 25.4 13.8 1.3 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE AAA_10 PF12846.7 EON34288.1 - 0.002 17.1 0.0 0.041 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain Adeno_IVa2 PF02456.15 EON34288.1 - 0.0091 14.8 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein T2SSE PF00437.20 EON34288.1 - 0.0095 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EON34288.1 - 0.014 14.3 0.0 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 EON34288.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 EON34288.1 - 0.027 14.9 0.0 0.086 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EON34288.1 - 0.034 13.9 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EON34288.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EON34288.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 EON34288.1 - 0.32 11.0 0.9 0.75 9.8 0.9 1.8 1 1 0 1 1 1 0 Dynamin family TerC PF03741.16 EON34289.1 - 1.5e-53 181.1 7.7 1.5e-53 181.1 7.7 2.3 3 0 0 3 3 3 1 Integral membrane protein TerC family YCII PF03795.14 EON34290.1 - 7.1e-11 42.4 0.0 8.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Acetyltransf_1 PF00583.25 EON34291.1 - 4e-10 39.9 0.2 6e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON34291.1 - 1.1e-09 38.6 0.2 1.9e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON34291.1 - 2.1e-07 30.9 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON34291.1 - 0.0023 18.0 0.1 0.0092 16.1 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON34291.1 - 0.0095 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase CDP-OH_P_transf PF01066.21 EON34292.1 - 3.3e-13 50.2 1.6 3.3e-13 50.2 1.6 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gate PF07670.14 EON34292.1 - 0.11 12.7 2.1 2.7 8.3 0.2 2.6 1 1 1 2 2 2 0 Nucleoside recognition HTH_31 PF13560.6 EON34293.1 - 3.4e-11 43.3 3.7 8.1e-11 42.1 3.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EON34293.1 - 2.7e-10 40.2 0.2 4.9e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EON34293.1 - 1.3e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EON34293.1 - 3.1e-05 24.3 0.1 4.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EON34293.1 - 0.00077 19.3 0.2 0.0013 18.5 0.2 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain PspA_IM30 PF04012.12 EON34294.1 - 5.1e-55 186.4 32.0 6.1e-55 186.2 32.0 1.0 1 0 0 1 1 1 1 PspA/IM30 family EF-G-binding_N PF07299.11 EON34294.1 - 5.1 7.7 7.3 3.2 8.3 5.0 1.9 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF948 PF06103.11 EON34294.1 - 6.3 7.1 10.9 0.7 10.2 1.8 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LUC7 PF03194.15 EON34294.1 - 8.5 6.0 22.4 3.5e+02 0.7 22.4 2.3 1 1 0 1 1 1 0 LUC7 N_terminus Glyco_trans_1_4 PF13692.6 EON34295.1 - 0.0021 18.5 0.6 0.004 17.6 0.6 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 UDPGT PF00201.18 EON34295.1 - 0.0028 16.5 0.0 0.0071 15.2 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EON34295.1 - 0.043 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PrpR_N PF06506.11 EON34295.1 - 0.089 12.4 0.1 8.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator DUF3046 PF11248.8 EON34296.1 - 4.5e-27 94.2 0.0 4.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3046) RecA PF00154.21 EON34297.1 - 1.2e-143 477.3 1.2 1.5e-143 477.0 1.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EON34297.1 - 1.3e-09 37.7 0.1 3.6e-09 36.3 0.1 1.6 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EON34297.1 - 1e-08 34.8 0.9 3.1e-07 30.0 0.9 2.5 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EON34297.1 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EON34297.1 - 0.00028 20.7 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain CobU PF02283.16 EON34297.1 - 0.0035 16.9 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 EON34297.1 - 0.0051 17.2 0.1 0.015 15.7 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EON34297.1 - 0.0059 16.2 0.4 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EON34297.1 - 0.014 15.8 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain RecX PF02631.16 EON34298.1 - 2.2e-28 99.2 0.1 4.6e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 RecX family DUF4661 PF15576.6 EON34298.1 - 0.092 12.6 0.4 0.1 12.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) CinA_KH PF18146.1 EON34298.1 - 0.11 12.7 0.2 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain BPD_transp_1 PF00528.22 EON34299.1 - 3.2e-22 79.2 19.4 3.2e-22 79.2 19.4 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component TOM13 PF08219.11 EON34299.1 - 0.043 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Outer membrane protein TOM13 DUF4179 PF13786.6 EON34299.1 - 7.2 7.2 9.6 1.3e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) BPD_transp_1 PF00528.22 EON34300.1 - 5.4e-13 49.1 16.9 5.4e-13 49.1 16.9 1.5 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 EON34301.1 - 9.8e-36 123.3 0.1 1.5e-35 122.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON34301.1 - 0.00086 19.0 0.2 0.006 16.2 0.2 2.1 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lig_chan-Glu_bd PF10613.9 EON34301.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site ABC_tran PF00005.27 EON34302.1 - 9.8e-35 120.0 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34302.1 - 6e-10 39.4 0.0 1.3e-05 25.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34302.1 - 1.5e-08 34.3 0.2 2.7e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON34302.1 - 0.0002 21.6 0.1 0.00062 20.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 EON34302.1 - 0.00028 19.7 0.0 0.21 10.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EON34302.1 - 0.0003 21.2 0.1 0.00044 20.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EON34302.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EON34302.1 - 0.0015 17.4 0.3 0.57 8.9 0.2 2.6 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 EON34302.1 - 0.0017 18.9 0.0 0.0036 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON34302.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EON34302.1 - 0.0019 18.1 0.1 0.0043 17.0 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase ATPase_2 PF01637.18 EON34302.1 - 0.013 15.4 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EON34302.1 - 0.014 15.9 0.0 0.051 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EON34302.1 - 0.015 15.1 0.1 0.072 12.9 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EON34302.1 - 0.018 15.2 0.1 0.023 14.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EON34302.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EON34302.1 - 0.026 14.9 0.5 0.48 10.9 0.5 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EON34302.1 - 0.041 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_15 PF13175.6 EON34302.1 - 0.049 13.3 0.0 3.4 7.3 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EON34302.1 - 0.056 13.0 0.1 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EON34302.1 - 0.06 12.5 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit CobU PF02283.16 EON34302.1 - 0.061 12.9 0.1 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SbcCD_C PF13558.6 EON34302.1 - 0.065 13.5 0.4 0.69 10.2 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EON34302.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 EON34302.1 - 0.091 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EON34302.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EON34302.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EON34302.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EON34302.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain HSM3_N PF18795.1 EON34302.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.3 1 1 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain Radical_SAM PF04055.21 EON34303.1 - 4.1e-29 102.1 0.0 5.9e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EON34303.1 - 2.1e-22 79.0 0.0 4.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 B12-binding PF02310.19 EON34303.1 - 0.011 15.8 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain DUF2795 PF11387.8 EON34303.1 - 0.12 12.5 0.2 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) Trypan_PARP PF05887.11 EON34304.1 - 0.00014 21.8 1.2 0.00022 21.2 1.2 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) UPF0139 PF03669.13 EON34304.1 - 0.033 14.0 2.2 0.033 14.0 2.2 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) Acyl_transf_3 PF01757.22 EON34304.1 - 0.038 13.1 8.6 0.048 12.7 8.6 1.1 1 0 0 1 1 1 0 Acyltransferase family CoA_binding_3 PF13727.6 EON34304.1 - 7.8 6.5 12.0 0.17 11.9 3.7 2.2 3 0 0 3 3 3 0 CoA-binding domain DUF4131 PF13567.6 EON34304.1 - 8.4 6.0 11.5 6.4 6.4 8.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF349 PF03993.12 EON34305.1 - 5.3e-50 167.6 42.9 1.6e-21 76.4 2.9 4.4 4 0 0 4 4 4 3 Domain of Unknown Function (DUF349) CENP-F_leu_zip PF10473.9 EON34305.1 - 0.053 13.5 4.5 3.8 7.5 0.1 3.3 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Trypan_PARP PF05887.11 EON34305.1 - 4.2 7.4 12.9 12 5.9 12.9 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4363 PF14276.6 EON34305.1 - 7.1 6.8 11.5 13 6.0 0.3 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4363) LigB PF02900.18 EON34306.1 - 0.0062 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase IPPT PF01715.17 EON34307.1 - 4.8e-70 235.9 0.0 5.8e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EON34307.1 - 2.8e-05 23.6 0.0 7.8e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EON34307.1 - 0.0032 17.6 1.4 0.018 15.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EON34307.1 - 0.0071 16.1 1.8 0.011 15.5 0.0 2.2 3 0 0 3 3 3 1 Cytidylate kinase AAA PF00004.29 EON34307.1 - 0.054 13.9 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EON34307.1 - 0.084 13.4 1.2 1.4 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain PGM_PMM_IV PF00408.20 EON34307.1 - 0.15 12.3 0.7 0.49 10.6 0.2 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DAP_epimerase PF01678.19 EON34308.1 - 3.9e-55 185.2 1.0 9.1e-34 116.2 0.1 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PUA PF01472.20 EON34308.1 - 0.075 13.0 0.1 0.94 9.5 0.0 2.7 2 1 1 3 3 3 0 PUA domain GTP-bdg_N PF13167.6 EON34309.1 - 5.6e-33 113.5 0.1 1.2e-32 112.4 0.1 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 EON34309.1 - 4.7e-29 100.8 12.0 7.9e-29 100.1 8.3 2.5 2 1 1 3 3 3 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 EON34309.1 - 1.4e-19 70.3 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EON34309.1 - 2.6e-05 23.8 0.0 0.00013 21.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EON34309.1 - 0.00063 19.8 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1_Xtn PF16897.5 EON34309.1 - 0.0015 18.5 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EON34309.1 - 0.0025 17.7 0.0 0.99 9.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EON34309.1 - 0.028 13.9 0.0 0.1 12.0 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family cobW PF02492.19 EON34309.1 - 0.034 13.7 4.8 0.092 12.3 0.1 3.0 2 2 2 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EON34309.1 - 0.049 14.0 1.2 0.076 13.4 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain PTS-HPr PF00381.19 EON34310.1 - 2.3e-18 66.2 0.2 2.5e-18 66.1 0.2 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PTS_EIIA_2 PF00359.22 EON34311.1 - 4e-29 101.4 0.0 6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 EON34311.1 - 1.1e-15 58.1 0.4 2.8e-15 56.8 0.4 1.7 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit SLBB PF10531.9 EON34311.1 - 0.011 15.6 0.1 0.046 13.6 0.1 2.1 2 0 0 2 2 2 0 SLBB domain PfkB PF00294.24 EON34312.1 - 9.2e-37 127.0 0.2 1.1e-36 126.7 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase peroxidase PF00141.23 EON34312.1 - 0.061 13.0 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 Peroxidase DeoRC PF00455.22 EON34313.1 - 1.6e-44 151.7 0.0 2.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EON34313.1 - 4.5e-16 58.3 0.4 8.1e-16 57.5 0.4 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EON34313.1 - 6.5e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 EON34313.1 - 4.9e-05 23.3 1.0 0.00019 21.4 0.4 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 EON34313.1 - 0.00011 21.8 0.8 0.00028 20.5 0.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FeoC PF09012.10 EON34313.1 - 0.00082 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_AsnC-type PF13404.6 EON34313.1 - 0.0053 16.5 0.2 0.0053 16.5 0.2 2.2 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Put_DNA-bind_N PF06971.13 EON34313.1 - 0.0096 15.9 1.0 0.078 13.0 0.1 2.5 2 0 0 2 2 2 1 Putative DNA-binding protein N-terminus MarR_2 PF12802.7 EON34313.1 - 0.012 15.5 1.5 0.042 13.8 0.9 2.2 1 1 1 2 2 2 0 MarR family HTH_28 PF13518.6 EON34313.1 - 0.015 15.4 0.3 0.045 13.9 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 EON34313.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 EON34313.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EON34313.1 - 0.07 12.9 0.2 0.23 11.3 0.2 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 EON34313.1 - 0.072 13.1 0.2 0.5 10.4 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 EON34313.1 - 0.08 12.8 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 EON34313.1 - 0.14 11.7 2.1 0.47 10.0 0.2 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 DUF4423 PF14394.6 EON34313.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF4148 PF13663.6 EON34313.1 - 1.2 9.4 7.2 0.16 12.2 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) PEP-utilizers_C PF02896.18 EON34314.1 - 3.2e-73 246.4 0.0 6.8e-73 245.3 0.0 1.4 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EON34314.1 - 1.6e-20 72.6 1.2 1.6e-20 72.6 1.2 2.5 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain PEP-utilisers_N PF05524.13 EON34314.1 - 1.3e-17 64.0 0.5 4e-17 62.4 0.5 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal LexA_DNA_bind PF01726.16 EON34315.1 - 7.8e-26 89.6 0.3 1.2e-25 89.1 0.3 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 EON34315.1 - 1.1e-13 50.9 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like MarR_2 PF12802.7 EON34315.1 - 0.00011 22.0 0.4 0.00024 20.9 0.4 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EON34315.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EON34315.1 - 0.002 17.9 0.1 0.0033 17.2 0.1 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EON34315.1 - 0.014 15.5 0.2 0.028 14.5 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 EON34315.1 - 0.023 14.6 0.1 0.05 13.5 0.1 1.6 1 1 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 EON34315.1 - 0.092 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EON34315.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4423 PF14394.6 EON34315.1 - 0.22 11.2 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) LysM PF01476.20 EON34317.1 - 1.1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain LptF_LptG PF03739.14 EON34317.1 - 0.19 10.5 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ATP-cone PF03477.16 EON34318.1 - 7.8e-16 58.4 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATP cone domain TFIIS_C PF01096.18 EON34318.1 - 0.019 14.8 1.4 0.041 13.7 1.4 1.6 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.6 EON34318.1 - 0.02 15.2 0.2 0.037 14.4 0.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 EON34318.1 - 0.032 14.2 1.4 0.059 13.3 1.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EON34318.1 - 0.075 12.6 0.7 4 7.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_4 PF13894.6 EON34318.1 - 2.5 9.2 3.8 6.3 7.9 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3418 PF11898.8 EON34319.1 - 8e-177 589.4 2.6 1.3e-176 588.8 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 EON34319.1 - 1.3e-17 63.9 0.0 2.5e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EON34319.1 - 4.1e-16 59.2 0.0 9.9e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EON34319.1 - 3.3e-10 40.3 0.0 7.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EON34319.1 - 2.3e-05 24.2 0.1 0.00018 21.4 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EON34319.1 - 3.4e-05 24.2 0.0 9.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EON34319.1 - 0.0014 17.8 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EON34319.1 - 0.0023 18.2 2.3 0.013 15.7 0.3 3.1 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EON34319.1 - 0.015 15.2 0.3 0.057 13.3 0.3 2.1 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EON34319.1 - 0.028 14.1 0.1 0.065 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EON34319.1 - 0.029 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EON34319.1 - 0.048 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EON34319.1 - 0.054 14.0 0.0 0.091 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EON34319.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 EON34319.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Aminotran_3 PF00202.21 EON34320.1 - 3.5e-84 282.8 0.0 4.4e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CMD PF02627.20 EON34321.1 - 1.1e-14 54.2 3.4 1.5e-14 53.8 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PhosphMutase PF10143.9 EON34321.1 - 0.08 12.8 0.3 13 5.6 0.0 2.2 2 0 0 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase AhpC-TSA PF00578.21 EON34322.1 - 8.7e-32 109.7 0.0 1.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EON34322.1 - 1.2e-13 51.0 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EON34322.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC LysR_substrate PF03466.20 EON34323.1 - 1.4e-48 165.0 17.3 1.2e-46 158.7 11.0 2.1 2 0 0 2 2 2 2 LysR substrate binding domain HTH_1 PF00126.27 EON34323.1 - 2.9e-18 65.6 2.7 9e-18 64.0 2.7 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF3516 PF12029.8 EON34324.1 - 8e-148 493.3 0.0 1e-147 492.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) DEAD PF00270.29 EON34324.1 - 2e-07 30.9 0.0 4.8e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EON34324.1 - 2.2e-05 24.8 0.1 3.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EON34324.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PAC2 PF09754.9 EON34325.1 - 7.1e-45 153.6 0.0 9.9e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Hex_IIIa PF02455.16 EON34325.1 - 0.24 10.1 0.3 0.34 9.6 0.3 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF4192 PF13830.6 EON34327.1 - 5.1e-59 200.9 20.4 5.8e-59 200.7 20.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) HrpJ PF07201.11 EON34327.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 HrpJ-like domain Fe_dep_repr_C PF02742.15 EON34328.1 - 2.2e-29 101.4 0.0 7e-29 99.7 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 EON34328.1 - 6.8e-22 77.4 0.1 5.3e-21 74.6 0.0 2.4 3 0 0 3 3 3 1 Iron dependent repressor, N-terminal DNA binding domain FeoA PF04023.14 EON34328.1 - 4.2e-08 33.3 0.4 1.4e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 FeoA domain MarR_2 PF12802.7 EON34328.1 - 7e-06 25.8 2.9 0.00012 21.9 0.1 2.8 2 1 0 2 2 2 1 MarR family HTH_27 PF13463.6 EON34328.1 - 1.4e-05 25.5 0.4 0.00045 20.7 0.3 2.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 EON34328.1 - 0.00015 21.6 0.4 0.002 18.1 0.3 2.7 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EON34328.1 - 0.00024 20.6 0.4 0.0014 18.2 0.0 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HemN_C PF06969.16 EON34328.1 - 0.0011 19.0 0.1 0.0026 17.8 0.1 1.7 1 0 0 1 1 1 1 HemN C-terminal domain HTH_20 PF12840.7 EON34328.1 - 0.008 16.2 1.2 0.069 13.2 0.1 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 EON34328.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_1 PF00126.27 EON34328.1 - 0.033 14.1 0.2 0.11 12.4 0.2 1.9 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 EON34328.1 - 0.13 12.1 1.7 1.5 8.7 0.2 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Hist_deacetyl PF00850.19 EON34329.1 - 1.3e-76 258.0 0.0 1.6e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ATP-grasp_5 PF13549.6 EON34330.1 - 3.1e-51 174.0 0.0 5.3e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EON34330.1 - 1.1e-46 158.1 0.5 7.9e-44 148.8 0.1 2.8 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EON34330.1 - 7.9e-16 58.6 2.5 3e-09 37.4 0.0 4.3 5 0 0 5 5 5 2 CoA binding domain Acetyltransf_1 PF00583.25 EON34330.1 - 1.8e-09 37.8 0.0 4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EON34330.1 - 9.7e-09 36.0 0.0 3.1e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 EON34330.1 - 2.7e-07 31.2 0.3 1.1e-06 29.3 0.0 2.2 2 1 0 2 2 2 1 CoA binding domain Acetyltransf_4 PF13420.7 EON34330.1 - 8.5e-07 29.2 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EON34330.1 - 0.0014 18.5 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EON34330.1 - 0.0024 18.3 0.1 0.0064 16.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EON34330.1 - 0.05 13.8 2.6 0.15 12.2 0.2 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON34330.1 - 0.076 13.0 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Sigma70_r3 PF04539.16 EON34331.1 - 1.8e-24 85.6 2.0 3.6e-24 84.6 1.3 1.9 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 EON34331.1 - 6.4e-22 77.1 0.3 1.6e-21 75.8 0.1 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EON34331.1 - 1.2e-20 72.7 3.7 4.5e-20 70.9 1.6 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 EON34331.1 - 9e-14 51.2 0.1 3.4e-13 49.3 0.1 2.1 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 HTH_15 PF12324.8 EON34331.1 - 0.0063 16.5 0.0 5.7 7.0 0.0 3.0 2 1 1 3 3 3 2 Helix-turn-helix domain of alkylmercury lyase Sigma70_r4_2 PF08281.12 EON34331.1 - 0.034 13.8 0.1 0.22 11.2 0.1 2.4 1 1 0 1 1 1 0 Sigma-70, region 4 DUF3099 PF11298.8 EON34332.1 - 4.2e-28 97.3 0.6 5.5e-28 96.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) DUF3039 PF11238.8 EON34333.1 - 2.4e-28 97.6 0.5 3.1e-28 97.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) ADK_lid PF05191.14 EON34333.1 - 0.02 14.9 0.7 0.2 11.6 0.2 2.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 EON34333.1 - 0.031 14.4 0.3 0.052 13.7 0.3 1.3 1 0 0 1 1 1 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 EON34333.1 - 0.074 13.5 1.3 4.3 7.9 0.7 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-UDP PF14569.6 EON34333.1 - 0.08 13.1 0.8 0.14 12.3 0.8 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_SprT PF17283.2 EON34333.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF4576 PF15144.6 EON34333.1 - 0.15 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Virul_fac_BrkB PF03631.15 EON34334.1 - 3.1e-37 128.6 23.8 3.7e-37 128.3 23.8 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF3007 PF11460.8 EON34334.1 - 0.07 13.4 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF1129 PF06570.11 EON34334.1 - 3.9 6.9 7.6 2.7 7.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) ResIII PF04851.15 EON34335.1 - 2.9e-16 59.9 0.0 4.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EON34335.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 EON34335.1 - 2.5e-07 30.6 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EON34335.1 - 8.9e-07 28.8 0.3 2.2e-06 27.5 0.3 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON34335.1 - 0.00022 21.5 0.0 0.0024 18.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EON34335.1 - 0.0003 21.1 0.2 0.00062 20.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.23 EON34335.1 - 0.0021 16.8 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_14 PF13173.6 EON34335.1 - 0.013 15.5 0.0 0.076 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.31 EON34335.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain TauE PF01925.19 EON34337.1 - 1.7e-40 139.2 32.5 6e-40 137.3 33.0 1.5 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DUF4396 PF14342.6 EON34337.1 - 9.3 6.6 8.6 21 5.4 1.3 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4396) Sigma70_r3 PF04539.16 EON34338.1 - 1.7e-28 98.5 0.9 1.7e-28 98.5 0.9 3.3 4 0 0 4 4 4 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 EON34338.1 - 6.1e-23 80.4 0.3 1.8e-22 78.8 0.3 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EON34338.1 - 1.3e-20 72.7 4.1 2.7e-18 65.2 0.7 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 EON34338.1 - 8.8e-17 60.8 0.1 3.6e-16 58.9 0.1 2.2 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 HC2 PF07382.11 EON34338.1 - 0.0026 17.9 22.7 0.0026 17.9 22.7 1.9 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 HTH_15 PF12324.8 EON34338.1 - 0.081 12.9 0.1 0.57 10.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase ROK PF00480.20 EON34339.1 - 1.3e-19 70.8 0.6 2.6e-17 63.3 0.5 2.7 1 1 1 2 2 2 2 ROK family Inositol_P PF00459.25 EON34340.1 - 2.8e-50 171.4 1.0 3.5e-50 171.0 1.0 1.2 1 1 0 1 1 1 1 Inositol monophosphatase family Bacillus_PapR PF05968.11 EON34340.1 - 0.12 12.2 0.0 0.95 9.4 0.0 2.4 2 0 0 2 2 2 0 Bacillus PapR protein LytR_C PF13399.6 EON34341.1 - 3.4e-12 47.2 0.0 7.9e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator Herpes_US9 PF06072.11 EON34341.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4193 PF13834.6 EON34342.1 - 7.8e-45 151.4 2.2 8.6e-45 151.2 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) DUF3093 PF11292.8 EON34343.1 - 2e-49 167.4 8.8 2.4e-49 167.2 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) dUTPase PF00692.19 EON34344.1 - 2.4e-33 114.6 0.0 2.9e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF3710 PF12502.8 EON34345.1 - 1.6e-53 181.0 0.7 2.2e-53 180.6 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) Hydrolase_4 PF12146.8 EON34346.1 - 0.0033 16.7 0.6 0.014 14.7 0.6 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EON34346.1 - 0.0037 17.2 0.6 0.007 16.2 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EON34346.1 - 0.065 13.1 0.7 10 5.9 0.1 2.1 1 1 0 2 2 2 0 Serine hydrolase RecG_wedge PF17191.4 EON34347.1 - 0.003 17.2 0.0 0.0059 16.2 0.0 1.4 1 1 0 1 1 1 1 RecG wedge domain VitD-bind_III PF09164.10 EON34347.1 - 0.062 13.3 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF3159 PF11361.8 EON34348.1 - 8.8e-69 231.0 15.8 1e-68 230.8 15.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3159) Trep_Strep PF09605.10 EON34348.1 - 0.13 12.2 5.9 0.33 10.9 6.1 1.6 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) PufQ PF05398.11 EON34348.1 - 0.4 10.8 5.5 0.32 11.1 1.3 2.4 2 0 0 2 2 2 0 PufQ cytochrome subunit TrkA_N PF02254.18 EON34349.1 - 7.7e-23 81.0 0.8 1e-22 80.6 0.8 1.2 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 EON34349.1 - 1.1e-14 54.0 0.1 3.8e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 TrkA-C domain ApbA PF02558.16 EON34349.1 - 2.7e-05 23.9 0.1 3.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EON34349.1 - 0.0003 21.2 0.9 0.00049 20.5 0.9 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EON34349.1 - 0.00055 20.0 0.2 0.00097 19.2 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EON34349.1 - 0.0012 18.8 0.2 0.0016 18.4 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EON34349.1 - 0.0016 18.4 0.1 0.0023 18.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 EON34349.1 - 0.0021 17.7 0.9 0.0028 17.3 0.8 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 EON34349.1 - 0.013 15.7 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiS PF02597.20 EON34349.1 - 0.016 15.8 0.2 0.16 12.6 0.0 2.3 2 1 0 2 2 2 0 ThiS family KORA PF16509.5 EON34349.1 - 0.024 14.9 0.2 0.26 11.6 0.1 2.1 1 1 0 2 2 2 0 TrfB plasmid transcriptional repressor F420_oxidored PF03807.17 EON34349.1 - 0.025 15.1 0.6 0.057 14.0 0.6 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EON34349.1 - 0.072 12.5 0.3 0.094 12.2 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gp_dh_N PF00044.24 EON34349.1 - 0.075 13.4 0.2 0.12 12.7 0.2 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EON34349.1 - 0.11 13.1 0.4 0.26 11.9 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Castor_Poll_mid PF06241.12 EON34349.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Sacchrp_dh_NADP PF03435.18 EON34349.1 - 0.12 12.6 0.9 0.41 10.9 0.9 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EON34350.1 - 1.7e-25 89.5 0.3 3.2e-25 88.7 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 EON34350.1 - 5.7e-05 22.9 0.1 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 TrkA-C domain DAO PF01266.24 EON34350.1 - 0.00017 21.3 0.2 0.00099 18.8 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 EON34350.1 - 0.00023 20.9 0.0 0.00046 19.8 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EON34350.1 - 0.00023 21.7 0.1 0.0016 18.9 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EON34350.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EON34350.1 - 0.0009 19.2 0.1 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EON34350.1 - 0.0035 17.5 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 EON34350.1 - 0.0035 17.9 0.2 0.0087 16.6 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EON34350.1 - 0.0056 16.1 0.1 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EON34350.1 - 0.0071 16.2 0.6 0.019 14.9 0.5 1.8 1 1 1 2 2 2 1 Rossmann-like domain FAD_binding_3 PF01494.19 EON34350.1 - 0.0074 15.6 0.1 0.0089 15.3 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EON34350.1 - 0.0099 15.1 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EON34350.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EON34350.1 - 0.023 15.0 0.3 0.046 14.0 0.1 1.7 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain XdhC_C PF13478.6 EON34350.1 - 0.023 15.2 0.1 0.041 14.4 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 EON34350.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.21 EON34350.1 - 0.028 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 EON34350.1 - 0.057 13.8 0.2 0.15 12.5 0.2 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EON34350.1 - 0.06 13.0 0.1 3.1 7.4 0.0 2.2 1 1 1 2 2 2 0 Starch synthase catalytic domain AdoHcyase_NAD PF00670.21 EON34350.1 - 0.069 13.2 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 EON34350.1 - 0.079 13.0 0.1 0.16 12.0 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 EON34350.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family DFP PF04127.15 EON34350.1 - 0.09 12.6 0.3 2.8 7.7 0.0 2.6 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein AlaDh_PNT_C PF01262.21 EON34350.1 - 0.091 12.0 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease_2 PF13520.6 EON34351.1 - 2.5e-27 95.8 33.0 3.7e-27 95.2 33.0 1.2 1 0 0 1 1 1 1 Amino acid permease Cuticle_4 PF15955.5 EON34351.1 - 0.27 12.0 2.0 0.83 10.4 2.0 1.8 1 0 0 1 1 1 0 Cuticle protein Reticulon PF02453.17 EON34351.1 - 2.6 8.0 11.6 4.2 7.3 0.9 3.6 3 0 0 3 3 3 0 Reticulon MTS PF05175.14 EON34352.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 EON34352.1 - 0.00025 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EON34352.1 - 0.0032 18.1 0.1 0.0094 16.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain DXP_synthase_N PF13292.6 EON34353.1 - 1.6e-105 352.2 0.0 2.4e-105 351.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EON34353.1 - 6.4e-36 123.7 0.0 1.3e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EON34353.1 - 2.5e-24 85.5 0.5 7.2e-24 84.0 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EON34353.1 - 1.9e-07 31.0 0.3 1.4e-05 25.0 0.1 3.2 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 EON34353.1 - 1.2e-05 25.5 0.1 4.5e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 EON34353.1 - 0.0011 18.0 0.1 0.083 11.8 0.0 2.2 2 0 0 2 2 2 2 Dehydrogenase E1 component GCS2 PF04107.13 EON34354.1 - 1.6e-41 142.6 1.6 2e-41 142.3 1.6 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Polyketide_cyc2 PF10604.9 EON34355.1 - 3.3e-13 50.1 0.0 4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DNA_pol_A_exo1 PF01612.20 EON34356.1 - 6e-30 104.2 0.0 8.7e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exoN PF18305.1 EON34356.1 - 1.2e-28 99.2 3.0 1.2e-28 99.2 3.0 2.6 3 0 0 3 3 3 1 3' to 5' exonuclease C-terminal domain HRDC PF00570.23 EON34356.1 - 3.4e-13 49.4 0.6 6.2e-13 48.5 0.1 1.7 2 0 0 2 2 2 1 HRDC domain Lipase_GDSL_2 PF13472.6 EON34356.1 - 0.016 15.6 0.5 0.034 14.5 0.2 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2156 PF09924.9 EON34356.1 - 0.066 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DUF3000 PF11452.8 EON34357.1 - 1.6e-67 226.4 0.1 1.8e-67 226.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3000) URO-D PF01208.17 EON34358.1 - 1.6e-124 415.6 0.0 1.9e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Methyltransf_23 PF13489.6 EON34358.1 - 0.2 11.5 0.0 0.59 9.9 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Amino_oxidase PF01593.24 EON34359.1 - 2.4e-25 89.8 7.9 5.2e-25 88.7 7.9 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EON34359.1 - 1.7e-14 53.7 0.3 1.7e-14 53.7 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EON34359.1 - 6.2e-08 32.6 4.5 5.6e-07 29.5 4.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EON34359.1 - 0.00025 21.1 0.4 0.0013 18.8 0.3 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EON34359.1 - 0.0034 16.6 0.1 0.0071 15.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EON34359.1 - 0.0036 16.6 0.0 0.017 14.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EON34359.1 - 0.0059 15.5 0.2 0.0087 14.9 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 EON34359.1 - 0.11 13.1 0.2 0.26 11.9 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON34359.1 - 0.13 11.6 0.9 0.18 11.1 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCRA PF06100.11 EON34359.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family Chlor_dismutase PF06778.12 EON34360.1 - 1.2e-73 246.9 0.0 1.3e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Chlorite dismutase DUF4550 PF15084.6 EON34360.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) SelR PF01641.18 EON34361.1 - 1.8e-52 176.5 0.0 2.1e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EON34361.1 - 0.0035 17.5 0.4 0.008 16.4 0.4 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 EON34361.1 - 0.021 13.7 0.7 1 8.2 0.1 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_10 PF10058.9 EON34361.1 - 0.031 14.0 0.4 0.73 9.6 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Ribosomal_L37e PF01907.19 EON34361.1 - 0.12 12.6 2.0 0.41 10.8 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein L37e GFA PF04828.14 EON34361.1 - 0.15 12.4 1.5 2.3 8.6 0.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.8 EON34361.1 - 0.28 11.5 1.8 0.97 9.7 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) DZR PF12773.7 EON34361.1 - 0.42 10.7 3.1 4.5 7.4 0.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon GT87 PF09594.10 EON34362.1 - 1.4e-33 116.6 35.6 1.4e-33 116.6 35.6 3.3 3 1 1 4 4 4 1 Glycosyltransferase family 87 DUF4231 PF14015.6 EON34362.1 - 0.5 10.9 2.5 0.67 10.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) PspC PF04024.12 EON34362.1 - 9.6 6.1 7.6 1.4 8.8 0.9 3.0 2 0 0 2 2 2 0 PspC domain Abhydrolase_1 PF00561.20 EON34363.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EON34363.1 - 5e-07 29.8 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein RibD_C PF01872.17 EON34364.1 - 8.6e-27 94.3 0.0 1e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain AFG1_ATPase PF03969.16 EON34365.1 - 2.7e-70 237.1 0.0 3.7e-50 170.8 0.0 2.1 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EON34365.1 - 0.00013 22.4 0.8 0.14 12.6 0.1 2.7 2 1 1 3 3 3 2 AAA ATPase domain DUF4027 PF13219.6 EON34365.1 - 0.087 12.7 1.6 6.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) KAP_NTPase PF07693.14 EON34365.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Bac_DnaA PF00308.18 EON34365.1 - 0.12 12.2 0.7 0.17 11.7 0.1 1.7 2 1 0 2 2 2 0 Bacterial dnaA protein IstB_IS21 PF01695.17 EON34365.1 - 0.13 11.9 0.0 0.45 10.2 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 EON34365.1 - 0.18 12.1 0.1 22 5.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 EON34365.1 - 0.21 11.5 0.3 2.5 8.0 0.0 2.5 2 1 1 3 3 3 0 NACHT domain AFG1_ATPase PF03969.16 EON34366.1 - 2.9e-66 223.8 0.0 5.9e-66 222.8 0.0 1.4 1 1 0 1 1 1 1 AFG1-like ATPase IstB_IS21 PF01695.17 EON34366.1 - 0.00012 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EON34366.1 - 0.0066 16.8 0.7 0.048 14.0 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EON34366.1 - 0.056 13.7 0.0 0.17 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EON34366.1 - 0.088 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EON34366.1 - 0.091 12.7 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Thx PF17070.5 EON34366.1 - 0.78 9.9 6.3 0.17 12.0 1.9 2.1 2 0 0 2 2 2 0 30S ribosomal protein Thx Acetyltransf_10 PF13673.7 EON34367.1 - 3.7e-11 43.0 0.0 6.2e-11 42.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON34367.1 - 1e-10 41.9 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON34367.1 - 0.00021 21.6 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON34367.1 - 0.0094 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Ldh_2 PF02615.14 EON34367.1 - 0.039 13.1 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Acetyltransf_9 PF13527.7 EON34367.1 - 0.04 14.0 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON34367.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Rhodanese PF00581.20 EON34368.1 - 6.9e-29 100.5 0.0 3.6e-13 50.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NAD_binding_8 PF13450.6 EON34368.1 - 0.13 12.5 0.7 0.44 10.8 0.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EON34369.1 - 9.3e-17 60.6 0.0 2.3e-15 56.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EON34369.1 - 4.3e-16 59.0 0.0 2.7e-14 53.1 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EON34369.1 - 4.9e-13 49.0 0.0 4.9e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34369.1 - 3.5e-11 43.2 0.2 1.9e-09 37.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EON34369.1 - 2.7e-10 40.0 0.0 2e-09 37.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON34369.1 - 1.1e-07 31.4 2.6 0.00028 20.3 0.6 3.1 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EON34369.1 - 1.1e-06 28.5 1.1 0.0018 17.9 0.5 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EON34369.1 - 2.3e-05 23.7 1.4 2.5e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EON34369.1 - 4.9e-05 23.8 0.0 0.091 13.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON34369.1 - 0.006 15.3 1.1 0.006 15.3 1.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EON34369.1 - 0.0098 15.2 1.5 0.075 12.3 0.1 2.4 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EON34369.1 - 0.049 13.7 0.1 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EON34369.1 - 0.34 9.9 0.2 0.97 8.4 0.4 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EON34369.1 - 1.3 9.0 7.7 2 8.4 0.1 3.8 3 2 1 4 4 4 0 FAD-NAD(P)-binding Nitroreductase PF00881.24 EON34370.1 - 9.1e-19 68.1 0.0 1.2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family AMP-binding PF00501.28 EON34371.1 - 1.2e-91 307.5 0.0 1.4e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34371.1 - 1.6e-20 73.8 0.3 3.9e-20 72.6 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltrn_RNA_4 PF09936.9 EON34371.1 - 0.042 13.7 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase TetR_C_24 PF17932.1 EON34372.1 - 2.8e-24 85.6 0.3 2.8e-24 85.6 0.3 1.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON34372.1 - 5.8e-15 54.8 0.5 9.9e-15 54.1 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 EON34372.1 - 4.1e-06 26.8 0.1 9.2e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EON34372.1 - 0.00038 20.7 1.5 0.00038 20.7 1.5 1.7 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_4 PF08359.11 EON34372.1 - 0.044 13.9 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region S-methyl_trans PF02574.16 EON34372.1 - 0.1 12.4 0.0 0.51 10.1 0.0 2.0 1 1 0 1 1 1 0 Homocysteine S-methyltransferase DsrC PF04358.13 EON34372.1 - 0.15 12.6 0.1 0.94 10.0 0.0 2.0 2 0 0 2 2 2 0 DsrC like protein CoA_transf_3 PF02515.17 EON34373.1 - 4.7e-74 249.7 0.0 5.7e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III TENA_THI-4 PF03070.16 EON34375.1 - 0.11 12.2 0.3 0.24 11.2 0.3 1.6 1 1 0 1 1 1 0 TENA/THI-4/PQQC family RelA_SpoT PF04607.17 EON34376.1 - 8.7e-35 119.5 0.0 1.3e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins EspA PF03433.13 EON34376.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 EspA-like secreted protein DUF732 PF05305.14 EON34377.1 - 2.2e-08 34.3 4.7 1.9e-06 28.2 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF732) DUF732 PF05305.14 EON34378.1 - 0.00022 21.5 0.4 0.0003 21.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) GT87 PF09594.10 EON34381.1 - 1.3e-58 198.6 35.6 1.3e-58 198.6 35.6 3.6 3 1 0 3 3 3 1 Glycosyltransferase family 87 PGPGW PF09656.10 EON34382.1 - 3.6e-24 84.0 4.2 3.6e-24 84.0 4.2 2.1 2 0 0 2 2 2 1 Putative transmembrane protein (PGPGW) SieB PF14163.6 EON34382.1 - 0.55 9.7 3.5 0.7 9.4 0.9 2.0 1 1 1 2 2 2 0 Super-infection exclusion protein B tRNA-synt_2b PF00587.25 EON34383.1 - 1.5e-35 122.7 0.0 2.6e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EON34383.1 - 3.4e-15 55.9 0.0 7.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EON34383.1 - 1.8e-13 50.4 0.0 3.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Metal_resist PF13801.6 EON34383.1 - 0.1 12.8 0.3 0.37 11.0 0.3 1.9 1 0 0 1 1 1 0 Heavy-metal resistance HIT PF01230.23 EON34384.1 - 4.6e-14 52.9 0.0 6.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EON34384.1 - 3e-05 24.5 0.0 4.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EON34384.1 - 0.0016 18.3 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EON34384.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain CDP-OH_P_transf PF01066.21 EON34385.1 - 1.7e-10 41.5 3.9 1.7e-10 41.5 3.9 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Lip_A_acyltrans PF03279.13 EON34386.1 - 3.3e-60 203.8 0.0 3.9e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Glyco_trans_1_4 PF13692.6 EON34387.1 - 3e-33 115.1 0.3 1.1e-32 113.3 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EON34387.1 - 1.9e-27 95.9 0.0 2.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON34387.1 - 1.7e-24 86.7 0.1 2.6e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON34387.1 - 1.2e-13 51.8 0.8 1.2e-13 51.8 0.8 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EON34387.1 - 7.9e-12 45.4 0.1 2.3e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EON34387.1 - 7.6e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like LemA PF04011.12 EON34388.1 - 4.2e-06 26.7 0.3 2.7e-05 24.1 0.2 2.2 1 1 1 2 2 2 1 LemA family PhoR PF11808.8 EON34388.1 - 0.14 12.6 1.7 5.2 7.6 0.4 2.3 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR SOR_SNZ PF01680.17 EON34389.1 - 1.2e-106 355.1 2.1 1.5e-106 354.8 2.1 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EON34389.1 - 1.3e-08 34.4 7.7 6.5e-06 25.6 0.8 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EON34389.1 - 6.2e-05 22.2 0.1 0.017 14.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EON34389.1 - 0.0003 20.3 0.3 0.0029 17.1 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 EON34389.1 - 0.00045 19.5 2.1 0.015 14.5 0.1 2.9 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 EON34389.1 - 0.0029 17.1 1.0 0.0029 17.1 1.0 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.21 EON34389.1 - 0.0049 16.1 0.0 0.095 11.8 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 EON34389.1 - 0.0092 15.0 0.5 0.0092 15.0 0.5 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EON34389.1 - 0.024 13.8 0.2 0.041 13.0 0.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EON34389.1 - 0.089 12.0 0.1 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PP2C PF00481.21 EON34390.1 - 9.9e-11 41.8 0.0 5.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EON34390.1 - 1e-09 38.4 1.0 1.6e-09 37.7 1.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EON34390.1 - 2.1e-07 31.0 3.8 1e-06 28.8 3.8 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Usp PF00582.26 EON34390.1 - 1.7e-06 28.6 2.1 0.03 14.8 1.0 2.2 2 0 0 2 2 2 2 Universal stress protein family NUDIX_2 PF13869.6 EON34390.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase GerE PF00196.19 EON34392.1 - 4.6e-07 29.3 0.0 8.6e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EON34392.1 - 0.014 15.1 0.4 0.046 13.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 EON34392.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 EON34392.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain 4HBT_3 PF13622.6 EON34393.1 - 9.1e-57 193.2 3.3 1.1e-56 192.8 3.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EON34393.1 - 9.2e-40 135.6 0.0 3e-31 108.0 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase SNO PF01174.19 EON34394.1 - 2.5e-60 203.5 0.0 2.8e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EON34394.1 - 2.2e-08 34.0 0.0 6.2e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EON34394.1 - 6.6e-05 22.7 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 EON34394.1 - 0.0042 16.9 0.0 0.021 14.6 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EON34394.1 - 0.13 12.0 0.1 7.6 6.2 0.0 2.7 2 1 0 2 2 2 0 Peptidase C26 Transcrip_reg PF01709.20 EON34395.1 - 3.1e-90 301.8 0.1 3.5e-90 301.6 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator RuvC PF02075.17 EON34396.1 - 1.6e-56 190.3 0.5 2e-56 190.0 0.5 1.1 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC RuvX PF03652.15 EON34396.1 - 0.034 14.5 0.0 0.088 13.2 0.0 1.8 1 0 0 1 1 1 0 Holliday junction resolvase RuvA_N PF01330.21 EON34397.1 - 3.1e-20 72.0 0.0 5.8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 RuvA N terminal domain HHH_5 PF14520.6 EON34397.1 - 1.6e-14 54.2 0.7 7e-14 52.2 0.1 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain RuvA_C PF07499.13 EON34397.1 - 3e-10 40.4 0.2 1.1e-09 38.6 0.0 2.0 2 0 0 2 2 2 1 RuvA, C-terminal domain Transposase_20 PF02371.16 EON34397.1 - 0.00016 21.9 0.1 0.42 10.9 0.0 2.8 3 0 0 3 3 3 2 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 EON34397.1 - 0.0014 18.8 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif HHH PF00633.23 EON34397.1 - 0.0031 17.3 0.1 0.37 10.8 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.7 EON34397.1 - 0.0062 16.6 0.0 0.24 11.5 0.0 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 EON34397.1 - 0.014 15.7 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.8 EON34397.1 - 0.016 15.5 0.0 0.92 9.8 0.0 2.8 2 1 0 3 3 3 0 Pathogenicity locus HHH_8 PF14716.6 EON34397.1 - 0.028 14.8 0.0 0.21 11.9 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain Ribosomal_S13 PF00416.22 EON34397.1 - 0.076 13.4 0.0 2.6 8.5 0.0 2.2 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DNA_pol_lambd_f PF10391.9 EON34397.1 - 0.08 12.8 0.0 7.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda RuvB_N PF05496.12 EON34398.1 - 4e-73 244.4 0.0 8.1e-73 243.4 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 EON34398.1 - 1.8e-30 104.5 3.3 3.5e-30 103.6 3.3 1.5 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 EON34398.1 - 5.8e-23 80.6 0.0 1.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 EON34398.1 - 7.4e-17 62.0 0.0 1.3e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON34398.1 - 1.7e-06 28.1 0.1 0.00017 21.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON34398.1 - 4.1e-05 24.0 1.1 0.0004 20.8 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EON34398.1 - 0.00013 21.3 0.5 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EON34398.1 - 0.00015 21.2 0.5 0.13 11.6 0.1 3.1 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EON34398.1 - 0.0023 17.6 0.0 0.8 9.4 0.0 2.2 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 EON34398.1 - 0.0059 16.5 0.1 0.1 12.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON34398.1 - 0.011 16.0 0.3 1.9 8.8 0.0 2.5 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EON34398.1 - 0.019 14.3 0.3 0.032 13.5 0.3 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EON34398.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Resolvase PF00239.21 EON34398.1 - 0.026 14.6 0.1 0.082 13.0 0.0 1.8 2 0 0 2 2 2 0 Resolvase, N terminal domain RNA_helicase PF00910.22 EON34398.1 - 0.028 14.8 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EON34398.1 - 0.029 14.1 2.0 0.099 12.4 0.1 2.7 2 2 1 3 3 3 0 IstB-like ATP binding protein AAA_14 PF13173.6 EON34398.1 - 0.041 13.9 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EON34398.1 - 0.048 13.8 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 EON34398.1 - 0.075 13.6 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Transposase_20 PF02371.16 EON34398.1 - 0.17 12.2 1.3 0.87 9.9 0.0 2.6 3 0 0 3 3 2 0 Transposase IS116/IS110/IS902 family NACHT PF05729.12 EON34398.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 EON34398.1 - 0.27 10.4 0.0 3.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) YajC PF02699.15 EON34399.1 - 3.8e-18 65.1 0.1 4.8e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit CcmD PF04995.14 EON34399.1 - 0.13 12.4 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SecD_SecF PF02355.16 EON34400.1 - 6.6e-09 35.4 10.3 1e-08 34.8 10.3 1.2 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 EON34400.1 - 0.00035 20.0 0.0 0.001 18.4 0.0 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 EON34400.1 - 0.038 11.7 9.1 0.052 11.2 9.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PT-TG PF14449.6 EON34400.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 Pre-toxin TG MMPL PF03176.15 EON34400.1 - 0.4 9.6 28.5 0.02 13.8 21.1 2.3 2 1 1 3 3 3 0 MMPL family SecD_SecF PF02355.16 EON34401.1 - 2.4e-55 186.9 11.6 4e-55 186.1 11.6 1.3 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 EON34401.1 - 3.7e-07 29.4 0.1 8.7e-07 28.2 0.1 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif MerC PF03203.14 EON34401.1 - 0.033 14.6 2.1 0.033 14.6 2.1 2.4 3 0 0 3 3 3 0 MerC mercury resistance protein MG4 PF17789.1 EON34401.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 Macroglobulin domain MG4 SBP_bac_5 PF00496.22 EON34402.1 - 2.9e-19 69.3 0.0 4.1e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Pribosyltran PF00156.27 EON34403.1 - 1.5e-18 66.8 0.8 2.6e-18 66.1 0.8 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EON34403.1 - 3e-06 26.8 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.6 EON34403.1 - 0.037 14.1 0.2 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain MctB PF11382.8 EON34403.1 - 0.06 13.0 3.0 0.089 12.5 1.4 1.8 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB PRTase_2 PF15609.6 EON34403.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase HD_4 PF13328.6 EON34404.1 - 1.7e-48 164.3 1.5 4.4e-48 162.9 1.5 1.8 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 EON34404.1 - 1.4e-36 125.3 0.0 2.9e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 EON34404.1 - 3.4e-23 81.5 0.0 8.6e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 EON34404.1 - 5e-17 62.3 0.2 1.1e-16 61.2 0.2 1.6 1 0 0 1 1 1 1 ACT domain HD PF01966.22 EON34404.1 - 5.8e-13 49.1 0.8 2.3e-12 47.2 0.8 2.1 1 0 0 1 1 1 1 HD domain ACT PF01842.25 EON34404.1 - 4.3e-11 42.4 2.3 8.6e-11 41.4 0.4 2.6 3 0 0 3 3 3 1 ACT domain Nitroreductase PF00881.24 EON34404.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Nitroreductase family Ub-Mut7C PF14451.6 EON34404.1 - 0.16 11.9 1.2 0.39 10.6 0.1 2.3 3 0 0 3 3 3 0 Mut7-C ubiquitin Pro_isomerase PF00160.21 EON34405.1 - 9.9e-16 58.4 0.0 1.5e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF664 PF04978.12 EON34405.1 - 0.16 12.4 1.7 0.23 11.9 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Insulin_TMD PF17870.1 EON34405.1 - 0.31 11.2 3.6 0.6 10.2 3.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Lactamase_B PF00753.27 EON34406.1 - 3.1e-24 86.1 2.4 3.4e-17 63.1 0.6 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EON34406.1 - 9.9e-07 28.5 0.1 1.4e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EON34406.1 - 0.054 13.4 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain tRNA-synt_His PF13393.6 EON34407.1 - 6.2e-44 150.5 0.0 1e-43 149.8 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EON34407.1 - 1.9e-19 70.3 0.0 3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EON34407.1 - 1.5e-13 50.7 0.0 3.7e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 EON34407.1 - 0.00031 20.3 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF885 PF05960.11 EON34408.1 - 2.3e-141 473.0 1.8 2.6e-141 472.9 1.8 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Zn_peptidase PF04228.13 EON34409.1 - 7.6e-69 232.3 0.6 9e-69 232.1 0.6 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Peptidase_M91 PF14891.6 EON34409.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Effector protein tRNA-synt_2 PF00152.20 EON34410.1 - 9.5e-99 330.4 0.0 1.2e-98 330.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EON34410.1 - 3e-18 65.6 0.1 6.3e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 EON34410.1 - 9.9e-15 54.6 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 EON34410.1 - 0.17 11.3 0.2 0.73 9.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EON34410.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF2126 PF09899.9 EON34412.1 - 0 1160.9 0.0 0 1160.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) Bact_transglu_N PF08379.10 EON34412.1 - 1.6e-24 86.6 0.5 4.5e-24 85.2 0.5 1.8 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 EON34412.1 - 1.3e-20 73.9 0.0 6.7e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily CP_ATPgrasp_2 PF14403.6 EON34413.1 - 1.2e-117 393.1 0.1 1.8e-117 392.5 0.1 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 EON34413.1 - 1.2e-98 330.2 0.0 1.8e-98 329.6 0.0 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Alpha-E PF04168.12 EON34413.1 - 4.2e-62 210.6 5.2 4.2e-62 210.6 5.2 1.5 2 0 0 2 2 2 1 A predicted alpha-helical domain with a conserved ER motif. DUF1515 PF07439.11 EON34413.1 - 2.1 8.4 6.0 0.44 10.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Bact_transglu_N PF08379.10 EON34414.1 - 4.8e-24 85.0 3.1 6.4e-24 84.7 1.8 1.8 2 0 0 2 2 2 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 EON34414.1 - 1.5e-20 73.7 0.1 2.6e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 EON34414.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain Choline_kinase PF01633.20 EON34415.1 - 0.0032 17.1 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase MgsA_C PF12002.8 EON34416.1 - 1.7e-67 226.6 0.1 2.5e-67 226.0 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EON34416.1 - 1.7e-25 89.1 5.0 1.8e-25 89.1 2.3 2.4 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 EON34416.1 - 1.9e-14 54.2 0.0 4.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EON34416.1 - 5.5e-13 49.0 0.1 1.6e-12 47.4 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EON34416.1 - 2.6e-09 37.2 0.2 9.7e-09 35.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON34416.1 - 1.5e-07 31.9 5.0 0.00042 20.7 0.3 2.9 1 1 2 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.21 EON34416.1 - 8.5e-07 28.6 0.5 0.0049 16.3 0.2 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EON34416.1 - 2.1e-06 27.6 0.2 0.021 14.5 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EON34416.1 - 1.3e-05 25.4 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 EON34416.1 - 5.4e-05 23.7 0.0 9.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EON34416.1 - 6.1e-05 23.3 0.9 0.045 14.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EON34416.1 - 6.4e-05 22.8 1.5 0.00027 20.7 1.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EON34416.1 - 7.2e-05 22.7 1.0 0.00022 21.1 0.1 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EON34416.1 - 0.00036 20.6 0.1 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EON34416.1 - 0.00066 19.9 0.3 0.003 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EON34416.1 - 0.00088 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON34416.1 - 0.0011 18.6 3.1 0.0013 18.4 0.4 2.4 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 EON34416.1 - 0.0045 16.2 0.7 0.069 12.3 0.2 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EON34416.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EON34416.1 - 0.0088 16.4 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase MCM PF00493.23 EON34416.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 1 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 EON34416.1 - 0.014 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EON34416.1 - 0.02 15.2 2.5 0.84 10.0 0.3 2.5 1 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EON34416.1 - 0.029 13.5 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EON34416.1 - 0.045 14.0 0.3 0.11 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 EON34416.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EON34416.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 EON34416.1 - 0.068 13.0 0.0 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 EON34416.1 - 0.081 12.4 0.1 0.27 10.7 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EON34416.1 - 0.082 12.8 1.2 1.4 8.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.22 EON34416.1 - 0.086 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 EON34416.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EON34416.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EON34416.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EON34416.1 - 0.2 11.5 0.1 5.9 6.7 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EON34416.1 - 0.22 10.8 0.3 0.61 9.4 0.1 1.7 2 0 0 2 2 2 0 KaiC AAA_13 PF13166.6 EON34416.1 - 0.3 9.7 0.0 0.42 9.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EON34416.1 - 0.55 10.0 1.7 18 5.0 0.2 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase tRNA-synt_2c PF01411.19 EON34417.1 - 3.8e-196 652.9 0.0 4.5e-196 652.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EON34417.1 - 7.2e-22 78.3 0.3 1.6e-21 77.2 0.3 1.6 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 EON34417.1 - 2.8e-15 56.1 0.3 5.7e-15 55.1 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RuvX PF03652.15 EON34418.1 - 8.5e-42 142.7 0.1 9.5e-42 142.6 0.1 1.0 1 0 0 1 1 1 1 Holliday junction resolvase YceG PF02618.16 EON34419.1 - 1.3e-58 198.8 0.0 1.6e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 YceG-like family PBP1_TM PF14812.6 EON34419.1 - 9.8 6.6 11.6 2.4 8.6 0.2 3.6 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Shikimate_dh_N PF08501.11 EON34420.1 - 1.7e-19 69.8 0.0 3.4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EON34420.1 - 1.1e-11 44.3 0.4 2.1e-11 43.4 0.4 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EON34420.1 - 0.00088 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Peptidase_A24 PF01478.18 EON34421.1 - 3.3e-12 46.8 10.3 5.2e-12 46.1 10.3 1.3 1 0 0 1 1 1 1 Type IV leader peptidase family Chorismate_synt PF01264.21 EON34422.1 - 3.6e-120 400.6 4.8 4.1e-120 400.4 4.8 1.0 1 0 0 1 1 1 1 Chorismate synthase SKI PF01202.22 EON34423.1 - 3.7e-40 137.6 0.0 4.2e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EON34423.1 - 2.1e-06 28.3 0.0 5.2e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON34423.1 - 0.00033 20.8 0.1 0.0014 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EON34423.1 - 0.0005 20.2 0.1 0.0045 17.1 0.0 1.9 1 1 0 2 2 2 1 Cytidylate kinase-like family dNK PF01712.19 EON34423.1 - 0.00081 19.3 0.0 0.088 12.6 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EON34423.1 - 0.0027 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase CoaE PF01121.20 EON34423.1 - 0.0033 17.1 0.1 0.0063 16.2 0.1 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA PF00004.29 EON34423.1 - 0.05 14.0 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EON34423.1 - 0.13 12.7 0.0 1.3 9.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain DHQ_synthase PF01761.20 EON34424.1 - 9e-93 310.2 0.0 1.1e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EON34424.1 - 1.7e-08 34.5 0.8 2.2e-07 30.9 0.2 2.4 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EON34424.1 - 6.5e-06 25.2 2.3 1.9e-05 23.7 2.3 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Acyl_transf_3 PF01757.22 EON34425.1 - 0.0028 16.8 2.7 0.0031 16.6 2.7 1.1 1 0 0 1 1 1 1 Acyltransferase family CarS-like PF01864.17 EON34425.1 - 0.003 17.6 1.0 0.003 17.6 1.0 1.6 2 0 0 2 2 2 1 CDP-archaeol synthase Sbt_1 PF05982.12 EON34425.1 - 0.015 14.5 0.4 0.015 14.5 0.4 1.6 2 0 0 2 2 2 0 Na+-dependent bicarbonate transporter superfamily Yip1 PF04893.17 EON34425.1 - 0.02 14.6 10.4 0.029 14.1 10.4 1.3 1 0 0 1 1 1 0 Yip1 domain DUF5518 PF17647.1 EON34425.1 - 0.85 9.8 23.4 0.061 13.5 12.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5518) VirB3 PF05101.13 EON34425.1 - 5.7 7.3 9.5 2.1 8.6 0.9 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Peptidase_M24 PF00557.24 EON34426.1 - 2e-59 200.8 1.5 3e-59 200.2 1.5 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EON34426.1 - 7.5e-18 65.5 0.1 1.4e-17 64.6 0.1 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain EFP_N PF08207.12 EON34427.1 - 1.1e-25 89.4 0.2 2.4e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 EON34427.1 - 1.7e-25 88.5 0.1 6.9e-25 86.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.20 EON34427.1 - 8.2e-23 80.2 0.1 1.3e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF5042 PF16445.5 EON34427.1 - 0.041 12.3 0.0 0.16 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5042) NusB PF01029.18 EON34428.1 - 3.5e-29 101.8 0.1 4.1e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 NusB family Pribosyltran PF00156.27 EON34429.1 - 1.6e-18 66.7 0.3 1.9e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EON34429.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EON34429.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase OTCace_N PF02729.21 EON34430.1 - 4.3e-41 140.4 0.0 6.5e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EON34430.1 - 8.4e-21 74.7 0.0 4.6e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Amidohydro_1 PF01979.20 EON34431.1 - 1.8e-20 73.5 0.1 8.2e-20 71.4 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family DHOase PF12890.7 EON34431.1 - 8.9e-12 45.1 0.0 6e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Dihydro-orotase-like Amidohydro_3 PF07969.11 EON34431.1 - 2.8e-09 37.0 3.9 3.3e-05 23.5 0.2 2.4 1 1 0 2 2 2 2 Amidohydrolase family CPSase_sm_chain PF00988.22 EON34433.1 - 4.3e-47 159.1 0.7 1.5e-46 157.4 0.3 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EON34433.1 - 6.7e-38 130.4 0.0 1e-37 129.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EON34433.1 - 3.6e-08 33.4 0.1 0.0031 17.3 0.1 2.6 2 1 0 3 3 3 2 Peptidase C26 CPSase_L_D2 PF02786.17 EON34434.1 - 4.2e-102 340.1 0.0 9.8e-66 221.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EON34434.1 - 5e-38 130.2 0.0 1.1e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 EON34434.1 - 7.3e-23 80.6 0.0 3.2e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EON34434.1 - 5.2e-12 45.7 0.0 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EON34434.1 - 2.9e-11 43.3 0.0 5.5e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EON34434.1 - 2.5e-10 40.2 0.0 4.4e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EON34434.1 - 2.2e-07 31.1 0.0 0.00015 21.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 EON34434.1 - 7.8e-05 22.2 0.0 0.089 12.2 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 EON34434.1 - 0.00096 18.8 0.0 0.89 9.1 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 EON34434.1 - 0.0019 17.8 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 EON34434.1 - 0.0024 17.5 0.0 0.14 11.8 0.0 3.1 3 1 0 3 3 3 1 ATP-grasp domain OMPdecase PF00215.24 EON34435.1 - 1.1e-35 123.3 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribosomal_S13 PF00416.22 EON34436.1 - 0.013 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 RPN13_C PF16550.5 EON34436.1 - 0.064 13.4 0.1 0.095 12.9 0.1 1.4 1 1 0 1 1 1 0 UCH-binding domain Guanylate_kin PF00625.21 EON34437.1 - 3.5e-40 137.6 0.0 4.2e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EON34437.1 - 2.6e-05 24.7 0.3 5.3e-05 23.7 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EON34437.1 - 0.00015 21.9 0.3 0.0019 18.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EON34437.1 - 0.00054 20.0 0.0 0.00095 19.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EON34437.1 - 0.0026 18.3 0.0 0.0076 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON34437.1 - 0.0028 17.3 0.1 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON34437.1 - 0.0033 17.7 0.3 0.054 13.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON34437.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EON34437.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EON34437.1 - 0.059 12.8 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 EON34437.1 - 0.13 12.7 0.0 0.92 9.9 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EON34437.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EON34437.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 EON34437.1 - 0.19 12.2 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EON34437.1 - 0.26 10.8 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_pol_Rpb6 PF01192.22 EON34438.1 - 2.2e-13 49.9 0.0 3.2e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DFP PF04127.15 EON34439.1 - 1.1e-64 217.7 1.0 2.9e-63 213.1 0.0 2.1 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 EON34439.1 - 1.1e-35 122.7 0.1 2.6e-35 121.5 0.0 1.6 2 0 0 2 2 2 1 Flavoprotein Glyco_transf_4 PF13439.6 EON34439.1 - 0.0028 17.7 0.1 3.5 7.6 0.1 2.9 3 0 0 3 3 3 2 Glycosyltransferase Family 4 YjeF_N PF03853.15 EON34439.1 - 0.0066 16.3 3.2 0.023 14.6 0.2 2.7 3 0 0 3 3 3 1 YjeF-related protein N-terminus PTS_IIB PF02302.17 EON34439.1 - 0.037 14.7 1.1 3.2 8.5 0.3 2.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Glyco_trans_4_4 PF13579.6 EON34439.1 - 0.04 14.3 0.3 0.04 14.3 0.3 3.1 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain F420_oxidored PF03807.17 EON34439.1 - 0.55 10.8 4.3 3.5 8.3 3.1 2.6 2 2 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent S-AdoMet_synt_C PF02773.16 EON34440.1 - 1e-64 216.6 0.0 1.7e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EON34440.1 - 7.2e-46 155.3 0.0 2.8e-45 153.4 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EON34440.1 - 9.3e-41 138.5 0.1 9.3e-41 138.5 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain PriA_3primeBD PF17764.1 EON34441.1 - 6.9e-17 61.1 0.0 1.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) zf-CHY PF05495.12 EON34441.1 - 0.12 12.8 4.3 0.23 12.0 4.3 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-ribbon_3 PF13248.6 EON34441.1 - 0.77 9.2 3.3 1.9 8.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EON34441.1 - 2.1 8.4 7.6 0.1 12.6 2.4 1.5 2 0 0 2 2 2 0 zinc-ribbons C1_2 PF03107.16 EON34441.1 - 3.3 8.1 8.8 0.23 11.8 3.2 1.8 1 1 1 2 2 2 0 C1 domain HypA PF01155.19 EON34441.1 - 5.5 7.0 7.9 22 5.1 7.9 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Formyl_trans_N PF00551.19 EON34442.1 - 1.8e-34 119.1 0.0 2.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EON34442.1 - 5e-21 74.8 0.0 7.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Methyltr_RsmB-F PF01189.17 EON34443.1 - 2.6e-46 157.8 0.0 3.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 EON34443.1 - 2.2e-23 82.9 0.0 3.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 NusB family POR PF01558.18 EON34443.1 - 0.005 16.9 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Methyltransf_25 PF13649.6 EON34443.1 - 0.12 13.1 0.2 3.6 8.3 0.2 2.6 1 1 0 1 1 1 0 Methyltransferase domain RibD_C PF01872.17 EON34444.1 - 3.1e-25 89.2 0.1 5.3e-25 88.4 0.1 1.4 1 1 0 1 1 1 1 RibD C-terminal domain AHSA1 PF08327.11 EON34445.1 - 3.5e-23 82.2 0.6 4.1e-23 82.0 0.6 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EON34445.1 - 7.4e-06 26.3 5.1 8.1e-06 26.2 5.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EON34445.1 - 0.089 13.0 1.3 0.12 12.5 1.3 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport HTH_20 PF12840.7 EON34446.1 - 1.5e-14 53.8 0.0 2.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EON34446.1 - 2.2e-05 24.2 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EON34446.1 - 0.00084 19.2 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 MarR family Cdc6_C PF09079.11 EON34446.1 - 0.05 13.6 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DprA_WH PF17782.1 EON34446.1 - 0.051 13.7 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain DUF222 PF02720.17 EON34447.1 - 1.4e-13 51.0 10.0 2.3e-13 50.3 10.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF222) PP2C_2 PF13672.6 EON34447.1 - 0.051 13.2 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C T7SS_ESX_EspC PF10824.8 EON34449.1 - 7.1 7.2 11.3 0.63 10.6 2.8 3.3 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Ribul_P_3_epim PF00834.19 EON34450.1 - 4.4e-78 261.2 0.0 5.1e-78 261.0 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EON34450.1 - 0.00061 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 EON34450.1 - 0.016 14.8 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 EON34450.1 - 0.027 13.9 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein RibD_C PF01872.17 EON34451.1 - 6.2e-40 137.2 0.1 9e-40 136.6 0.1 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 EON34451.1 - 2.2e-14 53.2 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Ldh_2 PF02615.14 EON34451.1 - 2.9e-05 23.4 2.2 4.3e-05 22.8 2.2 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MafB19-deam PF14437.6 EON34451.1 - 7.1e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Lum_binding PF00677.17 EON34452.1 - 3e-50 168.2 1.3 5.1e-26 90.5 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain DHBP_synthase PF00926.19 EON34453.1 - 7.1e-86 286.6 0.1 1.1e-85 286.0 0.1 1.3 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 EON34453.1 - 1.4e-73 245.9 0.0 4.1e-73 244.4 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase II DMRL_synthase PF00885.19 EON34454.1 - 7e-47 158.8 1.4 8.2e-47 158.6 1.4 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase bPH_6 PF10756.9 EON34455.1 - 2.7e-13 49.8 1.9 6.2e-13 48.6 1.9 1.6 1 0 0 1 1 1 1 Bacterial PH domain UvrC_HhH_N PF08459.11 EON34456.1 - 8e-49 165.5 0.0 3.2e-48 163.5 0.0 2.0 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 EON34456.1 - 1.5e-10 41.2 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH_2 PF12826.7 EON34456.1 - 9e-09 35.3 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif UVR PF02151.19 EON34456.1 - 1.6e-08 34.0 3.1 3.5e-08 32.9 3.1 1.6 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_5 PF14520.6 EON34456.1 - 7.3e-08 32.9 0.0 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EON34456.1 - 6.4e-05 22.6 0.2 0.00054 19.7 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2742 PF10888.8 EON34456.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) 5_3_exonuc PF01367.20 EON34456.1 - 0.21 12.2 0.2 8.3 7.1 0.0 3.2 3 1 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Urease_alpha PF00449.20 EON34456.1 - 0.4 11.0 1.8 0.39 11.0 0.2 1.8 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain ATP_bind_2 PF03668.15 EON34457.1 - 1.6e-93 313.1 0.0 1.8e-93 312.9 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 EON34457.1 - 0.0014 19.2 0.2 0.0057 17.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain SO_alpha_A3 PF17806.1 EON34457.1 - 0.043 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain AAA_22 PF13401.6 EON34457.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain UL16 PF17622.2 EON34457.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 AAA_33 PF13671.6 EON34457.1 - 0.085 13.0 0.4 2.6 8.2 0.4 2.4 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 EON34457.1 - 0.098 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DNA_photolyase PF00875.18 EON34457.1 - 0.14 12.1 0.5 0.23 11.4 0.5 1.3 1 0 0 1 1 1 0 DNA photolyase UPF0052 PF01933.18 EON34458.1 - 4e-69 233.1 0.0 4.9e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 WhiA_N PF10298.9 EON34459.1 - 2.4e-26 91.6 0.0 5.2e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 WhiA N-terminal LAGLIDADG-like domain LAGLIDADG_WhiA PF14527.6 EON34459.1 - 6.2e-25 87.1 0.0 1.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 WhiA LAGLIDADG-like domain HTH_WhiA PF02650.14 EON34459.1 - 1.4e-19 70.2 0.0 2.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 WhiA C-terminal HTH domain Gp_dh_C PF02800.20 EON34460.1 - 2.2e-68 228.8 0.0 3.9e-68 228.0 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EON34460.1 - 1.3e-32 112.2 0.1 2.5e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EON34460.1 - 0.00036 21.2 0.3 0.0029 18.3 0.3 2.2 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EON34460.1 - 0.057 13.5 0.2 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PGK PF00162.19 EON34461.1 - 2e-139 464.8 0.0 2.4e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3006 PF11213.8 EON34461.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) TIM PF00121.18 EON34462.1 - 6e-85 284.5 0.0 6.8e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SecG PF03840.14 EON34463.1 - 1.9e-16 59.9 7.6 2.1e-16 59.7 7.6 1.0 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF3367 PF11847.8 EON34463.1 - 0.031 12.2 0.3 0.03 12.2 0.3 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase PEPcase PF00311.17 EON34464.1 - 9.7e-271 900.4 0.0 1.1e-270 900.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Glucosamine_iso PF01182.20 EON34465.1 - 5.7e-75 252.0 0.0 6.5e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase OpcA_G6PD_assem PF10128.9 EON34466.1 - 5.8e-81 271.7 0.3 6.9e-81 271.5 0.3 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit G6PD_C PF02781.16 EON34467.1 - 3.4e-112 374.4 0.0 4.1e-112 374.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EON34467.1 - 1.1e-63 215.0 0.0 1.7e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain TAL_FSA PF00923.19 EON34468.1 - 3.4e-82 276.0 0.1 3.9e-82 275.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Transketolase_N PF00456.21 EON34469.1 - 1.5e-138 461.3 0.0 1.9e-138 461.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EON34469.1 - 2.6e-41 141.3 0.0 8.1e-41 139.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EON34469.1 - 4.4e-13 49.2 0.0 1.1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF498 PF04430.14 EON34469.1 - 0.039 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF3343 PF11823.8 EON34469.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) UbiA PF01040.18 EON34470.1 - 5.3e-63 212.7 24.2 6.7e-63 212.3 24.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ADH_zinc_N PF00107.26 EON34471.1 - 9.5e-26 90.3 0.0 2.5e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON34471.1 - 1.5e-13 52.0 0.1 2.9e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON34471.1 - 8.1e-11 41.8 0.0 6.3e-10 38.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EON34471.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain COX15-CtaA PF02628.15 EON34473.1 - 1e-25 90.5 29.4 3.4e-14 52.7 20.6 3.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein ABC2_membrane_3 PF12698.7 EON34473.1 - 0.029 13.5 8.8 0.062 12.4 1.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF962 PF06127.11 EON34473.1 - 2 8.5 6.5 0.71 10.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF962) GPI2 PF06432.11 EON34473.1 - 7 6.0 11.9 1.2 8.5 3.3 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase ABC2_membrane PF01061.24 EON34474.1 - 5.2e-13 48.9 7.1 7.9e-13 48.3 7.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON34474.1 - 2.5e-11 43.3 7.7 2.5e-11 43.3 7.7 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EON34474.1 - 5.5e-05 22.6 14.6 5.5e-05 22.6 14.6 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 EON34474.1 - 0.0043 16.6 4.9 0.019 14.5 4.6 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EON34474.1 - 0.47 10.4 14.2 17 5.3 12.6 3.2 1 1 2 3 3 3 0 ABC-2 family transporter protein ABC_tran PF00005.27 EON34475.1 - 3.2e-26 92.5 0.0 5.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34475.1 - 7.3e-10 39.1 0.1 2.7e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34475.1 - 0.00068 19.1 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON34475.1 - 0.0035 17.6 0.1 0.099 12.9 0.1 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EON34475.1 - 0.022 15.0 0.1 0.18 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON34475.1 - 0.036 13.8 0.0 0.058 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EON34475.1 - 0.05 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MycE_N PF17843.1 EON34475.1 - 0.079 13.5 0.6 0.2 12.2 0.3 1.8 2 0 0 2 2 2 0 MycE methyltransferase N-terminal AAA_23 PF13476.6 EON34475.1 - 0.094 13.2 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EON34475.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EON34475.1 - 0.14 11.9 0.0 17 5.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein UcrQ PF02939.16 EON34476.1 - 0.11 12.4 0.0 0.86 9.6 0.0 2.6 1 0 0 1 1 1 0 UcrQ family HTH_20 PF12840.7 EON34477.1 - 5.4e-08 32.8 0.1 3.2e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 EON34477.1 - 5.8e-07 29.4 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 EON34477.1 - 1.5e-06 28.0 0.0 3.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EON34477.1 - 2e-06 27.2 0.0 4.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EON34477.1 - 6.4e-06 26.0 0.8 2.1e-05 24.3 0.1 2.2 3 0 0 3 3 2 1 MarR family TrmB PF01978.19 EON34477.1 - 8.6e-05 22.3 0.0 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 EON34477.1 - 0.00031 20.5 0.1 0.00098 18.9 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EON34477.1 - 0.00065 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.12 EON34477.1 - 0.002 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_42 PF06224.12 EON34477.1 - 0.0023 17.5 0.6 0.0032 17.0 0.6 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Sigma70_r4 PF04545.16 EON34477.1 - 0.0033 16.9 1.5 0.0087 15.6 0.0 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_34 PF13601.6 EON34477.1 - 0.0036 17.4 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain FaeA PF04703.12 EON34477.1 - 0.0041 17.5 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 FaeA-like protein LexA_DNA_bind PF01726.16 EON34477.1 - 0.0099 15.6 0.0 0.048 13.4 0.0 2.0 2 0 0 2 2 2 1 LexA DNA binding domain HTH_28 PF13518.6 EON34477.1 - 0.019 15.1 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EON34477.1 - 0.022 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain AT_hook PF02178.19 EON34477.1 - 0.022 14.6 0.1 0.052 13.4 0.1 1.7 1 0 0 1 1 1 0 AT hook motif HTH_9 PF08221.11 EON34477.1 - 0.023 14.8 0.0 0.08 13.0 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DprA_WH PF17782.1 EON34477.1 - 0.025 14.7 0.4 0.065 13.3 0.4 1.8 1 0 0 1 1 1 0 DprA winged helix domain HTH_CodY PF08222.11 EON34477.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain Dimerisation2 PF16864.5 EON34477.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain UPF0051 PF01458.17 EON34478.1 - 3.2e-77 259.1 0.1 4.1e-77 258.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.17 EON34479.1 - 4e-71 239.2 0.0 5.4e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Hydrolase_4 PF12146.8 EON34479.1 - 0.014 14.6 0.9 0.022 14.0 0.9 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ABC_tran PF00005.27 EON34480.1 - 4.4e-21 75.8 0.0 5.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EON34480.1 - 3.7e-06 26.6 0.1 0.00049 19.6 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON34480.1 - 4.1e-06 26.8 0.0 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON34480.1 - 0.00029 20.5 0.3 0.00057 19.6 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 EON34480.1 - 0.0062 15.3 0.0 0.039 12.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EON34480.1 - 0.0082 15.7 0.1 0.025 14.1 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EON34480.1 - 0.0089 16.5 0.1 0.097 13.1 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EON34480.1 - 0.01 16.4 0.1 0.017 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON34480.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 EON34480.1 - 0.053 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EON34480.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 EON34480.1 - 0.08 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase Aminotran_5 PF00266.19 EON34481.1 - 2.8e-133 444.4 0.0 3.6e-133 444.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EON34481.1 - 0.00092 17.8 0.0 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3759 PF12585.8 EON34481.1 - 0.019 15.0 0.3 0.019 15.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) NifU_N PF01592.16 EON34482.1 - 6.6e-30 103.9 0.0 8.4e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain FeS_assembly_P PF01883.19 EON34483.1 - 1.5e-19 69.9 0.6 2.8e-19 69.1 0.6 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein DUF1992 PF09350.10 EON34484.1 - 9.6e-22 76.9 0.1 1.7e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Acyl_transf_3 PF01757.22 EON34485.1 - 3e-25 89.0 31.0 3e-25 89.0 31.0 1.6 2 0 0 2 2 2 1 Acyltransferase family Lycopene_cycl PF05834.12 EON34488.1 - 4.6e-46 157.6 0.0 5.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EON34488.1 - 3.9e-05 23.0 0.1 0.00043 19.6 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EON34488.1 - 0.0011 18.3 0.1 0.0016 17.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain XdhC_C PF13478.6 EON34488.1 - 0.0032 17.9 0.0 0.0081 16.7 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain TrkA_N PF02254.18 EON34488.1 - 0.0055 17.0 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 EON34488.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EON34488.1 - 0.017 15.1 0.4 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EON34488.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EON34488.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EON34488.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EON34488.1 - 0.031 13.3 0.8 0.1 11.7 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EON34488.1 - 0.19 10.8 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 EON34489.1 - 7.9e-59 199.1 7.3 9.1e-59 198.9 7.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34489.1 - 1.2e-43 148.9 3.7 1.4e-43 148.6 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34489.1 - 1.3e-07 31.7 2.3 1.9e-07 31.2 2.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EON34489.1 - 0.00065 19.1 0.3 0.0042 16.4 0.0 2.1 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EON34489.1 - 0.0017 17.9 0.7 0.0036 16.8 0.4 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 EON34489.1 - 0.013 15.5 0.1 0.032 14.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.18 EON34489.1 - 0.038 13.9 0.2 0.072 13.0 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC_tran PF00005.27 EON34490.1 - 2e-46 157.9 0.0 1.1e-23 84.3 0.0 3.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EON34490.1 - 1.6e-21 77.4 5.7 2.1e-06 27.8 0.1 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EON34490.1 - 5.4e-09 36.0 5.3 5.4e-09 36.0 5.3 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EON34490.1 - 1.1e-07 31.5 0.3 0.55 9.6 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EON34490.1 - 2.2e-07 31.0 0.0 0.074 13.3 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Arf PF00025.21 EON34490.1 - 4.1e-06 26.3 0.3 0.00032 20.2 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_18 PF13238.6 EON34490.1 - 1.5e-05 25.5 0.7 0.46 11.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EON34490.1 - 1.8e-05 24.4 1.3 0.23 11.3 0.1 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain DLIC PF05783.11 EON34490.1 - 2.5e-05 23.3 2.3 0.00012 21.1 0.0 2.5 3 0 0 3 3 3 1 Dynein light intermediate chain (DLIC) SRP54 PF00448.22 EON34490.1 - 0.00018 21.2 1.1 0.55 9.8 0.2 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EON34490.1 - 0.00034 20.7 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EON34490.1 - 0.00047 20.0 0.0 2.8 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON34490.1 - 0.00047 20.1 0.2 0.45 10.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_13 PF13166.6 EON34490.1 - 0.00048 18.9 3.9 0.31 9.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 EON34490.1 - 0.00051 20.3 0.7 1.7 8.9 0.3 3.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EON34490.1 - 0.00063 20.2 8.8 0.12 12.8 0.2 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 EON34490.1 - 0.00077 19.2 0.7 1.5 8.5 0.1 3.5 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 EON34490.1 - 0.0013 19.3 5.2 0.28 11.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain PduV-EutP PF10662.9 EON34490.1 - 0.0053 16.5 0.4 2.1 8.1 0.1 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 EON34490.1 - 0.007 15.7 4.2 1.1 8.5 0.1 3.6 4 0 0 4 4 4 1 Zeta toxin DUF3584 PF12128.8 EON34490.1 - 0.012 13.2 13.9 0.045 11.3 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) NACHT PF05729.12 EON34490.1 - 0.017 15.0 3.3 0.71 9.8 0.1 3.0 3 0 0 3 3 2 0 NACHT domain cobW PF02492.19 EON34490.1 - 0.019 14.6 2.0 0.87 9.1 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EON34490.1 - 0.019 15.4 2.7 1.7 9.1 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EON34490.1 - 0.022 14.4 1.3 4.8 6.7 0.0 3.9 4 1 0 4 4 4 0 AAA domain AAA_28 PF13521.6 EON34490.1 - 0.022 15.0 8.3 0.52 10.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain TsaE PF02367.17 EON34490.1 - 0.024 14.6 0.8 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EON34490.1 - 0.041 13.8 0.0 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 EON34490.1 - 0.049 13.9 0.1 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EON34490.1 - 0.049 13.8 11.4 0.16 12.1 0.1 4.1 3 2 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EON34490.1 - 0.56 10.2 1.4 8 6.5 0.1 3.1 4 0 0 4 4 3 0 AAA domain AAA_27 PF13514.6 EON34490.1 - 1.9 8.0 7.6 6.2 6.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 EON34490.1 - 2 8.1 16.3 1 9.1 0.5 4.0 4 1 0 4 4 3 0 AAA domain Aminotran_1_2 PF00155.21 EON34491.1 - 5.4e-40 137.7 0.0 6.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EON34491.1 - 0.0068 15.3 0.0 0.0098 14.8 0.0 1.2 1 0 0 1 1 1 1 Allinase DUF4164 PF13747.6 EON34491.1 - 0.01 16.1 0.8 0.022 15.0 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Aminotran_5 PF00266.19 EON34491.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V EspB_PE PF18625.1 EON34491.1 - 0.43 11.1 5.6 0.19 12.2 1.9 2.1 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain ACP_syn_III_C PF08541.10 EON34492.1 - 4.7e-21 74.8 0.0 1.8e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EON34492.1 - 3.7e-06 26.7 0.5 6.6e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TPP_enzyme_N PF02776.18 EON34494.1 - 1.8e-38 131.8 6.3 8.9e-38 129.6 0.6 3.7 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON34494.1 - 3.8e-25 88.5 0.2 1.9e-24 86.2 0.2 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON34494.1 - 1.3e-10 41.2 0.2 2.9e-10 40.0 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AMP-binding PF00501.28 EON34495.1 - 8e-81 271.8 0.1 9.7e-81 271.5 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34495.1 - 1.1e-19 71.2 0.1 2.3e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 EON34495.1 - 0.0096 16.2 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 FeoA domain GMC_oxred_C PF05199.13 EON34496.1 - 1.7e-11 44.8 0.0 3.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EON34496.1 - 5.7e-06 26.5 0.3 5.5e-05 23.3 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON34496.1 - 6.9e-06 25.5 0.2 0.0002 20.7 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EON34496.1 - 0.0013 18.1 0.8 0.063 12.6 0.0 2.7 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EON34496.1 - 0.0039 16.3 0.9 0.013 14.6 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain DUF761 PF05553.11 EON34496.1 - 0.035 13.6 0.3 0.057 13.0 0.3 1.3 1 0 0 1 1 1 0 Cotton fibre expressed protein GIDA PF01134.22 EON34496.1 - 0.21 10.6 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TetR_N PF00440.23 EON34497.1 - 6e-16 58.0 1.1 9.1e-16 57.4 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EON34497.1 - 0.00054 20.2 3.4 0.00054 20.2 3.4 2.2 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal HTH_31 PF13560.6 EON34497.1 - 0.0069 16.7 2.5 0.0069 16.7 2.5 3.2 2 2 1 3 3 3 1 Helix-turn-helix domain Repressor_Mnt PF11423.8 EON34497.1 - 0.04 13.7 0.5 0.091 12.6 0.5 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt Aconitase PF00330.20 EON34498.1 - 3.4e-178 593.4 0.0 4.6e-178 592.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EON34498.1 - 1.9e-40 138.2 0.0 3.7e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5368 PF17336.2 EON34499.1 - 0.018 15.2 0.1 0.033 14.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5368) NLPC_P60 PF00877.19 EON34500.1 - 8.2e-25 86.9 0.0 1.5e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family Pinin_SDK_memA PF04696.13 EON34500.1 - 0.8 9.8 8.3 2 8.5 8.3 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region AAA_3 PF07726.11 EON34501.1 - 6.4e-60 200.7 0.0 1.2e-59 199.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EON34501.1 - 1.3e-18 66.6 1.1 3.1e-18 65.4 1.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 EON34501.1 - 1.4e-15 57.5 0.0 2.5e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EON34501.1 - 0.00078 19.2 0.1 0.003 17.3 0.0 2.0 2 1 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 EON34501.1 - 0.017 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA PF00004.29 EON34501.1 - 0.17 12.3 0.0 0.55 10.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF58 PF01882.18 EON34502.1 - 4.8e-20 71.6 0.8 1.4e-19 70.1 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function DUF58 VWA_2 PF13519.6 EON34502.1 - 0.0012 19.5 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain T2SSM_b PF10741.9 EON34502.1 - 0.015 15.1 0.1 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b VWA PF00092.28 EON34503.1 - 3.4e-17 63.2 0.0 4.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EON34503.1 - 5.7e-16 59.1 0.1 1.1e-15 58.2 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 EON34503.1 - 2.2e-10 40.7 10.0 1e-09 38.6 9.4 2.2 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal VWA_CoxE PF05762.14 EON34503.1 - 0.00047 19.6 2.1 0.0026 17.2 2.1 2.1 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein DUF4131 PF13567.6 EON34503.1 - 0.037 13.7 7.7 0.49 10.0 6.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Ssl1 PF04056.14 EON34503.1 - 0.051 13.4 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Ssl1-like DUF4051 PF13260.6 EON34503.1 - 0.067 12.9 3.1 0.2 11.4 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) vWA-TerF-like PF10138.9 EON34503.1 - 0.15 12.1 0.1 0.28 11.3 0.0 1.4 2 0 0 2 2 2 0 vWA found in TerF C terminus Phage_holin_3_6 PF07332.11 EON34503.1 - 2.1 8.4 6.5 5.9 7.0 1.0 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4381 PF14316.6 EON34503.1 - 3.2 8.0 15.1 0.054 13.7 6.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) FixQ PF05545.11 EON34503.1 - 7.8 6.6 8.1 0.5 10.4 2.1 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ adh_short_C2 PF13561.6 EON34504.1 - 3.4e-60 203.5 2.8 7.8e-60 202.3 2.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34504.1 - 6.3e-48 162.8 2.4 1.5e-47 161.6 2.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34504.1 - 3e-17 63.1 0.7 6.1e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EON34504.1 - 3.7e-07 29.9 0.2 9.5e-07 28.5 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EON34504.1 - 7e-07 29.3 0.5 8.8e-07 29.0 0.5 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EON34504.1 - 0.002 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Dynein_light PF01221.18 EON34504.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 adh_short_C2 PF13561.6 EON34505.1 - 8e-55 185.9 0.1 9.5e-55 185.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34505.1 - 4.5e-11 42.6 0.0 9.2e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Oxidored_nitro PF00148.19 EON34505.1 - 0.08 11.7 0.0 0.22 10.2 0.0 1.6 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Ferrochelatase PF00762.19 EON34506.1 - 6.2e-96 321.2 0.0 7.1e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EON34506.1 - 5.1e-05 23.5 0.0 0.0077 16.6 0.0 2.5 2 0 0 2 2 2 2 CbiX DUF3097 PF11296.8 EON34508.1 - 3.1e-119 397.2 0.1 3.5e-119 397.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) NfeD PF01957.18 EON34509.1 - 6.2e-22 77.8 0.6 1.1e-21 77.0 0.6 1.4 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding VirB3 PF05101.13 EON34509.1 - 0.31 11.3 6.4 0.19 12.0 4.5 1.6 1 1 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF983 PF06170.12 EON34509.1 - 0.65 10.4 5.0 0.71 10.3 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF983) Band_7 PF01145.25 EON34510.1 - 5.7e-30 104.6 0.7 5.7e-30 104.6 0.7 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family Ntox1 PF15500.6 EON34510.1 - 0.25 11.7 2.1 0.78 10.1 2.0 2.0 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 FA_desaturase PF00487.24 EON34511.1 - 0.41 10.4 3.3 2 8.2 3.0 1.9 2 0 0 2 2 2 0 Fatty acid desaturase MarR_2 PF12802.7 EON34512.1 - 0.0014 18.5 0.2 0.0043 16.9 0.2 1.8 1 0 0 1 1 1 1 MarR family SatD PF16264.5 EON34512.1 - 0.003 17.2 0.0 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 SatD family (SatD) HTH_28 PF13518.6 EON34512.1 - 0.029 14.5 1.1 0.13 12.4 0.2 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EON34512.1 - 0.095 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_1 PF00126.27 EON34512.1 - 0.11 12.4 1.1 0.31 11.0 0.1 2.2 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.22 EON34512.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix DUF1203 PF06718.11 EON34512.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) SNARE_assoc PF09335.11 EON34513.1 - 4.5e-21 75.6 6.8 4.5e-21 75.6 6.8 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF4231 PF14015.6 EON34513.1 - 0.69 10.4 2.0 0.87 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) VirB8 PF04335.13 EON34513.1 - 2.3 8.0 5.8 43 3.8 0.2 3.1 2 1 1 3 3 3 0 VirB8 protein Colicin_V PF02674.16 EON34513.1 - 6.3 6.8 13.3 2.8 7.9 8.4 2.4 1 1 0 2 2 2 0 Colicin V production protein MM_CoA_mutase PF01642.22 EON34514.1 - 9.2e-106 354.4 0.0 1.7e-105 353.5 0.0 1.4 1 1 0 1 1 1 1 Methylmalonyl-CoA mutase MM_CoA_mutase PF01642.22 EON34515.1 - 7.5e-230 763.8 0.5 9.6e-230 763.5 0.5 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 EON34515.1 - 1.2e-15 57.7 3.1 2.3e-15 56.7 1.1 2.3 1 1 1 2 2 2 1 B12 binding domain PhnI PF05861.12 EON34515.1 - 0.019 13.9 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) HSCB_C PF07743.13 EON34515.1 - 7.8 7.1 9.5 14 6.3 0.2 3.1 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain MeaB PF03308.16 EON34516.1 - 2.2e-110 367.8 2.4 2.6e-110 367.6 2.4 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EON34516.1 - 8.3e-06 25.5 1.0 3.6e-05 23.4 1.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EON34516.1 - 7.6e-05 22.8 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EON34516.1 - 0.00018 21.4 0.1 0.0024 17.7 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EON34516.1 - 0.00033 20.4 0.7 0.0087 15.7 0.3 2.8 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 EON34516.1 - 0.00069 19.1 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.6 EON34516.1 - 0.0012 19.4 0.1 0.0026 18.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 EON34516.1 - 0.0022 18.0 0.1 0.008 16.1 0.0 1.8 1 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EON34516.1 - 0.0024 17.4 0.1 0.071 12.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EON34516.1 - 0.0024 17.9 0.4 0.01 15.9 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArsA_ATPase PF02374.15 EON34516.1 - 0.0025 17.0 0.7 0.0055 15.9 0.2 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_30 PF13604.6 EON34516.1 - 0.0029 17.3 1.4 0.0041 16.9 0.4 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EON34516.1 - 0.0093 16.2 0.1 0.029 14.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EON34516.1 - 0.013 15.2 0.1 0.047 13.4 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein Thymidylate_kin PF02223.17 EON34516.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.15 EON34516.1 - 0.024 14.5 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 NTPase ParA PF10609.9 EON34516.1 - 0.024 14.1 0.2 0.055 12.9 0.2 1.5 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 EON34516.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON34516.1 - 0.1 12.8 1.1 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EON34516.1 - 0.11 12.9 0.9 0.17 12.3 0.9 1.7 1 1 0 1 1 1 0 AAA domain RE_AccI PF09545.10 EON34516.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease KTI12 PF08433.10 EON34516.1 - 0.15 11.5 0.2 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Bac_luciferase PF00296.20 EON34517.1 - 2.3e-55 188.2 0.9 2.4e-53 181.6 0.9 2.0 1 1 0 1 1 1 1 Luciferase-like monooxygenase IU_nuc_hydro PF01156.19 EON34518.1 - 8.4e-83 278.4 3.0 9.6e-83 278.2 3.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_M23 PF01551.22 EON34519.1 - 4.8e-17 62.0 0.1 4.9e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M23 MS_channel PF00924.18 EON34520.1 - 1.4e-38 132.5 0.9 2.1e-38 132.0 0.9 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel Peptidase_M20 PF01546.28 EON34521.1 - 5e-37 127.6 0.3 1.5e-36 126.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON34521.1 - 2.3e-15 56.4 0.1 6.4e-15 55.0 0.1 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EON34521.1 - 9.3e-10 38.5 0.0 4.3e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 PBP PF01161.20 EON34522.1 - 3.4e-37 127.7 0.0 4.2e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DHO_dh PF01180.21 EON34523.1 - 5e-90 301.7 0.0 6.3e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase HPS3_N PF14761.6 EON34525.1 - 0.0077 15.8 0.0 0.8 9.2 0.0 2.1 2 0 0 2 2 2 2 Hermansky-Pudlak syndrome 3 PQQ PF01011.21 EON34525.1 - 0.057 13.4 10.3 7.8 6.6 0.2 5.5 6 0 0 6 6 6 0 PQQ enzyme repeat US22 PF02393.16 EON34525.1 - 0.11 12.8 0.9 21 5.4 0.1 3.2 3 1 0 3 3 3 0 US22 like NHL PF01436.21 EON34525.1 - 0.35 11.0 7.5 25 5.2 0.0 5.7 5 1 1 6 6 6 0 NHL repeat BacA PF02673.18 EON34526.1 - 1.6e-83 280.3 8.9 1.9e-83 280.1 8.9 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA TauE PF01925.19 EON34526.1 - 0.00048 19.8 16.2 0.00092 18.9 16.0 1.6 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4131 PF13567.6 EON34526.1 - 0.055 13.1 0.6 0.055 13.1 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2909 PF11137.8 EON34526.1 - 0.18 11.8 7.6 0.74 9.8 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2909) YwiC PF14256.6 EON34526.1 - 0.25 11.7 9.1 0.46 10.8 3.5 2.4 2 0 0 2 2 2 0 YwiC-like protein DAGK_prokar PF01219.19 EON34526.1 - 0.97 9.3 5.8 3 7.7 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase FA_desaturase PF00487.24 EON34526.1 - 2 8.2 11.7 0.66 9.8 1.2 2.1 2 0 0 2 2 2 0 Fatty acid desaturase HemY_N PF07219.13 EON34526.1 - 2.2 8.5 7.0 12 6.2 0.0 2.8 2 1 0 2 2 2 0 HemY protein N-terminus His_Phos_1 PF00300.22 EON34527.1 - 3.2e-40 137.9 0.0 4.2e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3090 PF11290.8 EON34528.1 - 3.4e-67 225.5 0.0 4.1e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3090) Rad50_zn_hook PF04423.14 EON34528.1 - 0.16 11.8 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif PI3_PI4_kinase PF00454.27 EON34529.1 - 1.2e-05 25.3 0.0 1.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_1e PF01406.19 EON34530.1 - 1.5e-86 290.5 0.0 1.8e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EON34530.1 - 4.8e-10 38.7 0.0 0.00011 21.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EON34530.1 - 1e-05 24.0 0.0 0.00045 18.6 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EON34530.1 - 0.011 14.6 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 EON34530.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) DUF4542 PF15075.6 EON34530.1 - 0.17 12.2 0.0 0.32 11.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) PAC2 PF09754.9 EON34532.1 - 6.4e-60 202.8 0.0 9.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 PAC2 family S-methyl_trans PF02574.16 EON34533.1 - 4.9e-60 203.6 0.0 1.3e-59 202.2 0.0 1.7 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 EON34533.1 - 5.8e-48 163.7 0.2 1.2e-47 162.6 0.2 1.6 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.17 EON34533.1 - 2.3e-30 106.0 0.0 3.6e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding_2 PF02607.17 EON34533.1 - 2.6e-24 85.5 0.0 9.6e-24 83.6 0.0 2.1 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 EON34533.1 - 3.1e-19 69.2 0.3 1.9e-18 66.7 0.2 2.6 2 0 0 2 2 2 1 B12 binding domain CdhD PF03599.16 EON34533.1 - 0.003 16.3 0.0 0.0059 15.4 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit UNC80 PF15778.5 EON34533.1 - 0.14 11.7 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Cation channel complex component UNC80 ECH_1 PF00378.20 EON34534.1 - 2.6e-42 144.9 0.0 3.2e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34534.1 - 1.9e-18 67.0 0.1 7.2e-18 65.2 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DHH PF01368.20 EON34535.1 - 7.9e-29 99.9 0.1 8.6e-28 96.5 0.1 2.1 2 1 0 2 2 2 1 DHH family DHHA2 PF02833.14 EON34535.1 - 3.9e-14 53.0 0.0 5.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain MFS_1 PF07690.16 EON34536.1 - 3.8e-53 180.7 39.9 6.5e-53 179.9 39.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EON34536.1 - 2.4e-06 26.3 11.1 2.4e-06 26.3 11.1 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Sugar_tr PF00083.24 EON34536.1 - 2.5e-05 23.4 7.2 2.5e-05 23.4 7.2 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter TraX PF05857.11 EON34536.1 - 0.093 12.8 0.9 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 TraX protein OATP PF03137.20 EON34536.1 - 1.9 6.6 9.8 0.11 10.8 0.3 2.7 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CinA PF02464.17 EON34538.1 - 2.6e-35 121.3 0.1 3.1e-35 121.0 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein DUF637 PF04830.13 EON34538.1 - 0.018 14.9 0.1 0.028 14.2 0.1 1.4 1 1 0 1 1 1 0 Possible hemagglutinin (DUF637) MLTR_LBD PF17765.1 EON34539.1 - 7.1e-29 101.1 7.2 7.1e-29 101.1 7.2 1.4 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 EON34539.1 - 2.1e-14 53.6 2.7 8e-14 51.7 2.7 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EON34539.1 - 9.9e-11 41.5 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EON34539.1 - 1.1e-08 35.0 0.0 3.1e-08 33.5 0.0 1.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 EON34539.1 - 0.017 15.0 0.1 0.074 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PAS_8 PF13188.7 EON34539.1 - 0.09 12.8 0.1 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 PAS domain HAD_2 PF13419.6 EON34540.1 - 4.5e-20 72.5 0.0 5.4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EON34540.1 - 1.3e-17 64.8 0.2 1e-16 61.9 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON34540.1 - 1e-07 32.6 0.0 1.3e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EON34540.1 - 3.9e-07 30.0 0.3 1.5e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EON34540.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIIA_gamma_N PF02268.16 EON34540.1 - 0.16 12.0 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain PRA-PH PF01503.17 EON34541.1 - 1.7e-07 31.6 0.0 1.9e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EON34541.1 - 1.8e-05 24.8 0.1 0.0002 21.5 0.2 1.9 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain HisG PF01634.18 EON34542.1 - 5e-41 140.3 0.0 6.8e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EON34542.1 - 1.6e-24 85.8 0.0 2.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EON34542.1 - 0.028 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like 4HBT_3 PF13622.6 EON34543.1 - 1.9e-29 103.7 2.1 2.2e-29 103.5 2.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily PDDEXK_1 PF12705.7 EON34544.1 - 1.3e-35 123.5 0.1 1.5e-35 123.3 0.1 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 EON34544.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2800) Cas_Cas4 PF01930.17 EON34544.1 - 0.00015 21.9 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF83 Exo5 PF09810.9 EON34544.1 - 0.016 14.7 0.3 4.6 6.6 0.0 2.9 2 1 0 3 3 3 0 Exonuclease V - a 5' deoxyribonuclease zf-Sec23_Sec24 PF04810.15 EON34544.1 - 0.084 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger GCD14_N PF14801.6 EON34545.1 - 7.3e-28 96.2 0.8 1.4e-27 95.2 0.8 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 EON34545.1 - 3.3e-21 76.1 0.0 9.7e-20 71.3 0.0 2.0 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EON34545.1 - 5.9e-09 36.0 0.0 8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EON34545.1 - 3.4e-07 30.9 0.0 7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON34545.1 - 6.5e-06 26.0 0.0 9.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON34545.1 - 0.00034 20.5 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON34545.1 - 0.001 19.8 0.0 0.0029 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EON34545.1 - 0.0013 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 EON34545.1 - 0.0069 17.4 0.1 0.013 16.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EON34545.1 - 0.015 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EON34545.1 - 0.037 14.2 0.0 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EON34545.1 - 0.053 12.9 0.1 0.25 10.6 0.1 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 EON34545.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F AAA PF00004.29 EON34546.1 - 9e-49 165.3 0.0 2.3e-48 163.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 EON34546.1 - 1.5e-24 85.4 0.1 5.4e-24 83.6 0.0 2.0 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain Prot_ATP_ID_OB PF16450.5 EON34546.1 - 6e-18 64.6 0.1 7.1e-17 61.1 0.0 2.6 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EON34546.1 - 1.6e-08 35.2 0.1 1.5e-06 28.7 0.0 2.8 2 1 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EON34546.1 - 1.3e-05 24.6 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.14 EON34546.1 - 2.3e-05 24.6 0.0 4.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EON34546.1 - 2.7e-05 24.4 0.0 0.0011 19.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EON34546.1 - 0.00017 22.0 0.0 0.00046 20.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 EON34546.1 - 0.00025 21.2 0.0 0.00052 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EON34546.1 - 0.00031 20.5 0.0 0.0011 18.8 0.0 2.0 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EON34546.1 - 0.0017 18.3 0.0 0.0045 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EON34546.1 - 0.0033 17.4 0.0 0.14 12.0 0.0 2.3 1 1 1 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 EON34546.1 - 0.0033 17.4 0.0 0.043 13.7 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EON34546.1 - 0.004 16.6 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EON34546.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EON34546.1 - 0.0056 15.9 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EON34546.1 - 0.0084 16.7 0.0 0.029 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EON34546.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EON34546.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EON34546.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EON34546.1 - 0.063 13.6 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EON34546.1 - 0.064 13.8 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 EON34546.1 - 0.09 12.7 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.6 EON34546.1 - 0.1 13.1 0.7 0.18 12.3 0.0 1.8 3 0 0 3 3 1 0 AAA domain Sigma54_activ_2 PF14532.6 EON34546.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 EON34546.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EON34546.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EON34546.1 - 0.14 11.9 0.0 0.54 9.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EON34546.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) VWA PF00092.28 EON34546.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain TsaE PF02367.17 EON34546.1 - 0.2 11.7 0.0 0.63 10.0 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EON34546.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FHA PF00498.26 EON34547.1 - 9.3e-37 125.2 0.2 2.2e-17 63.2 0.2 2.5 2 0 0 2 2 2 2 FHA domain ABC_tran PF00005.27 EON34547.1 - 8.2e-30 104.1 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Yop-YscD_cpl PF16697.5 EON34547.1 - 1.4e-29 102.3 0.0 2.1e-14 53.6 0.1 2.4 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain ABC2_membrane PF01061.24 EON34547.1 - 8.3e-19 67.8 7.2 8.3e-19 67.8 7.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EON34547.1 - 3.6e-11 42.8 9.8 3.6e-11 42.8 9.8 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EON34547.1 - 1.2e-09 38.4 0.1 3.8e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34547.1 - 0.0013 18.3 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EON34547.1 - 0.0063 16.8 1.0 0.05 13.9 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON34547.1 - 0.032 14.0 0.1 0.097 12.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EON34547.1 - 0.038 14.4 0.3 0.087 13.2 0.3 1.6 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 EON34547.1 - 0.11 12.7 0.1 1.5 9.1 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EON34547.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3902 PF13042.6 EON34547.1 - 0.14 11.7 0.9 0.39 10.3 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) DctQ PF04290.12 EON34547.1 - 0.2 11.6 7.8 0.019 14.9 2.2 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component AAA_15 PF13175.6 EON34547.1 - 0.22 11.2 0.0 10 5.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain F420H2_quin_red PF04075.14 EON34548.1 - 6e-10 39.4 0.8 7.8e-10 39.0 0.8 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 EON34548.1 - 0.001 19.2 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) DUF3417 PF11897.8 EON34549.1 - 6.5e-31 107.0 0.0 1.1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3417) Phosphorylase PF00343.20 EON34549.1 - 1.4e-26 93.0 0.0 5.5e-13 48.1 0.0 4.0 3 1 0 3 3 3 3 Carbohydrate phosphorylase Pup_ligase PF03136.15 EON34550.1 - 3.2e-181 603.1 0.0 3.7e-181 603.0 0.0 1.0 1 0 0 1 1 1 1 Pup-ligase protein PP-binding PF00550.25 EON34550.1 - 0.15 12.5 0.1 0.76 10.2 0.0 2.1 2 0 0 2 2 2 0 Phosphopantetheine attachment site Pup PF05639.11 EON34551.1 - 2.8e-22 79.4 3.6 3e-22 79.3 3.6 1.1 1 0 0 1 1 1 1 Pup-like protein YtxH PF12732.7 EON34551.1 - 0.024 15.2 0.1 0.03 14.8 0.1 1.2 1 0 0 1 1 1 0 YtxH-like protein Proteasome PF00227.26 EON34552.1 - 2.4e-34 118.5 0.0 3.5e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 EON34553.1 - 2.8e-30 105.2 0.0 3.6e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pup_ligase PF03136.15 EON34554.1 - 2.6e-157 524.4 0.0 5.2e-157 523.4 0.0 1.4 1 1 0 1 1 1 1 Pup-ligase protein WYL PF13280.6 EON34555.1 - 2.8e-32 112.1 0.1 5e-32 111.3 0.0 1.4 2 0 0 2 2 2 1 WYL domain WYL PF13280.6 EON34556.1 - 4.3e-27 95.3 0.2 5.6e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 WYL domain HTH_1 PF00126.27 EON34556.1 - 0.02 14.8 0.4 0.36 10.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 EON34556.1 - 0.02 14.7 0.1 0.063 13.1 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain MttA_Hcf106 PF02416.16 EON34557.1 - 7.7e-23 79.6 0.0 1.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 EON34558.1 - 1.3e-57 195.0 11.5 1.6e-57 194.6 11.5 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF1180 PF06679.12 EON34558.1 - 0.18 12.2 5.4 0.38 11.2 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DSHCT PF08148.12 EON34559.1 - 1.3e-33 116.0 0.0 1.1e-32 113.0 0.0 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EON34559.1 - 4.5e-17 62.4 0.0 7.4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EON34559.1 - 2.3e-06 27.7 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 EON34559.1 - 0.00039 20.4 0.0 0.006 16.5 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 EON34559.1 - 0.00082 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4333 PF14230.6 EON34560.1 - 2.1e-27 95.1 1.7 3.7e-27 94.4 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4333) 5_3_exonuc_N PF02739.16 EON34561.1 - 3e-46 157.2 0.0 3.9e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EON34561.1 - 1.3e-16 61.0 0.0 2.2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EON34561.1 - 0.00022 21.3 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EON34561.1 - 0.00075 20.1 0.1 0.0028 18.2 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain acVLRF1 PF18859.1 EON34561.1 - 0.068 13.5 1.4 4.1 7.7 0.3 2.5 1 1 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Nop PF01798.18 EON34561.1 - 0.076 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Peptidase_M24 PF00557.24 EON34562.1 - 3.4e-57 193.5 0.2 5.1e-57 192.9 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EON34562.1 - 8.2e-12 45.9 0.0 2e-11 44.7 0.0 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Putative_PNPOx PF01243.20 EON34563.1 - 5.2e-12 45.8 0.1 7.9e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON34563.1 - 0.00098 19.1 0.2 0.0011 18.9 0.2 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Acetyltransf_6 PF13480.7 EON34563.1 - 0.0048 17.1 0.8 0.035 14.2 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pyrid_ox_like PF16242.5 EON34563.1 - 0.052 13.1 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like adh_short PF00106.25 EON34564.1 - 7.6e-24 84.2 0.1 1e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON34564.1 - 3.5e-19 69.3 1.0 4.5e-19 68.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON34564.1 - 8.7e-12 45.3 1.3 1.2e-11 44.8 1.3 1.2 1 0 0 1 1 1 1 KR domain TP_methylase PF00590.20 EON34565.1 - 9.1e-22 78.0 4.0 2.1e-21 76.8 4.0 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_25 PF13649.6 EON34565.1 - 0.048 14.4 0.1 0.23 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 EON34565.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EON34565.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TP_methylase PF00590.20 EON34566.1 - 9.1e-39 133.6 3.1 1.1e-38 133.3 3.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiJ PF02571.14 EON34567.1 - 6.3e-71 238.6 0.0 7.2e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK ATPgrasp_N PF18130.1 EON34567.1 - 0.02 15.4 0.3 0.11 13.1 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp N-terminal domain TP_methylase PF00590.20 EON34568.1 - 7e-78 261.4 13.1 4.2e-48 164.1 0.9 2.1 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiC PF02570.15 EON34569.1 - 3.1e-70 235.9 1.1 3.4e-70 235.7 1.1 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase NIR_SIR_ferr PF03460.17 EON34570.1 - 2.8e-15 55.9 2.0 4.5e-12 45.6 0.1 3.2 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain CobN-Mg_chel PF02514.16 EON34571.1 - 0 1340.3 0.0 0 1340.1 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase FxsA PF04186.13 EON34572.1 - 1e-23 83.5 9.7 1.4e-23 83.1 9.7 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein SNARE_assoc PF09335.11 EON34572.1 - 0.0046 17.4 4.6 0.0067 16.9 4.3 1.4 1 1 0 1 1 1 1 SNARE associated Golgi protein DUF4381 PF14316.6 EON34572.1 - 0.42 10.9 2.5 0.67 10.2 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PRA1 PF03208.19 EON34572.1 - 0.44 10.2 4.5 0.63 9.7 4.5 1.2 1 0 0 1 1 1 0 PRA1 family protein RseC_MucC PF04246.12 EON34572.1 - 6.2 6.8 6.0 1.2 9.1 2.0 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Amidohydro_3 PF07969.11 EON34573.1 - 1.3e-74 252.4 18.2 1.5e-74 252.2 18.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EON34573.1 - 2.9e-06 26.8 3.4 0.043 13.1 0.0 3.4 3 1 0 4 4 4 2 Amidohydrolase family CN_hydrolase PF00795.22 EON34574.1 - 3.2e-17 62.7 0.0 4.5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 EON34574.1 - 0.00018 21.2 1.0 0.00063 19.5 0.1 2.5 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal DUF1269 PF06897.12 EON34574.1 - 4.6 7.6 8.3 17 5.8 3.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Glycos_transf_2 PF00535.26 EON34575.1 - 2.1e-28 99.3 0.0 2.5e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON34575.1 - 6.1e-09 36.1 0.1 7.8e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RbpA PF13397.6 EON34576.1 - 3.7e-39 133.5 0.0 4.2e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase-binding protein RXLR_WY PF18634.1 EON34576.1 - 0.05 13.5 0.2 0.081 12.9 0.2 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Aminoglyc_resit PF10706.9 EON34577.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase FXR_C1 PF16096.5 EON34577.1 - 0.49 10.6 0.2 0.49 10.6 0.2 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF475 PF04332.15 EON34578.1 - 6.3e-133 443.1 6.5 8.3e-133 442.7 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF475) TerC PF03741.16 EON34578.1 - 3.4e-16 59.4 12.4 5.7e-15 55.5 10.2 3.1 1 1 0 1 1 1 1 Integral membrane protein TerC family DUF3263 PF11662.8 EON34579.1 - 1.2e-05 25.1 0.1 1.9e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3263) Glyoxalase_4 PF13669.6 EON34581.1 - 1.5e-09 38.1 0.0 1e-06 29.0 0.0 2.9 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EON34581.1 - 9.6e-06 25.8 1.5 0.0013 18.9 0.4 3.1 2 2 1 3 3 3 1 Glyoxalase-like domain Glyoxalase PF00903.25 EON34581.1 - 0.074 13.3 0.0 0.65 10.2 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2236 PF09995.9 EON34582.1 - 3e-41 142.1 0.6 4.3e-41 141.6 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DAO PF01266.24 EON34583.1 - 4.1e-61 207.5 8.0 4.6e-61 207.4 8.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EON34583.1 - 3.5e-07 30.3 0.3 8e-07 29.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON34583.1 - 3.3e-06 26.6 2.8 5.3e-05 22.6 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EON34583.1 - 3.8e-06 26.5 0.2 0.034 13.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EON34583.1 - 0.00022 20.1 1.8 0.043 12.5 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EON34583.1 - 0.00089 18.7 2.2 0.0012 18.3 2.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EON34583.1 - 0.0021 18.6 0.7 0.0079 16.7 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON34583.1 - 0.0048 16.0 3.1 0.0048 16.0 3.1 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EON34583.1 - 0.0064 15.8 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 EON34583.1 - 0.013 15.9 0.1 0.025 15.0 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EON34583.1 - 0.032 13.5 1.3 0.086 12.1 1.1 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 EON34583.1 - 0.034 14.0 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EON34583.1 - 0.097 12.0 0.1 0.097 12.0 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EON34583.1 - 0.28 10.2 2.3 0.35 9.9 0.3 2.0 2 1 1 3 3 3 0 Lycopene cyclase protein NTP_transferase PF00483.23 EON34584.1 - 2.4e-31 109.2 0.0 3.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EON34584.1 - 2.4e-07 31.2 0.1 4.8e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EON34584.1 - 0.00021 20.4 0.0 0.46 9.4 0.0 2.3 2 0 0 2 2 2 2 L-fucokinase Hexapep PF00132.24 EON34584.1 - 0.0027 17.4 8.4 0.14 11.9 0.9 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EON34584.1 - 0.17 10.0 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) PGM_PMM_I PF02878.16 EON34585.1 - 2.1e-37 127.9 0.1 4.6e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EON34585.1 - 1.4e-25 89.9 0.3 1.7e-24 86.4 0.1 2.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EON34585.1 - 6.7e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EON34585.1 - 9.9e-08 32.1 0.0 9.9e-07 28.9 0.0 2.7 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HTH_18 PF12833.7 EON34586.1 - 3.9e-22 78.3 0.1 5.5e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EON34586.1 - 1.3e-13 50.6 0.0 9.8e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_5 PF01022.20 EON34586.1 - 0.092 12.6 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Glyoxalase PF00903.25 EON34587.1 - 1e-14 54.9 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EON34587.1 - 4e-05 23.5 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EON34587.1 - 0.00012 22.9 0.0 0.00022 22.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain ABC_tran PF00005.27 EON34588.1 - 5.5e-22 78.8 0.0 1.8e-13 51.2 0.0 3.8 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EON34588.1 - 7.5e-09 35.3 0.0 0.16 11.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EON34588.1 - 1.1e-07 32.4 0.3 0.038 14.4 0.0 3.2 4 0 0 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EON34588.1 - 3.2e-07 30.4 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EON34588.1 - 3.5e-07 29.9 0.1 0.021 14.6 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DnaJ_CXXCXGXG PF00684.19 EON34588.1 - 4.6e-06 26.9 4.8 0.008 16.5 0.2 3.3 3 0 0 3 3 3 1 DnaJ central domain UvrA_DNA-bind PF17755.1 EON34588.1 - 8e-06 26.2 0.0 2.7e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 UvrA DNA-binding domain AAA_15 PF13175.6 EON34588.1 - 3.3e-05 23.8 1.2 6 6.5 0.0 4.3 5 0 0 5 5 4 0 AAA ATPase domain AAA_33 PF13671.6 EON34588.1 - 8.1e-05 22.8 0.1 0.09 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EON34588.1 - 0.0001 22.3 12.4 0.073 12.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EON34588.1 - 0.00024 20.8 1.0 0.15 11.6 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EON34588.1 - 0.00034 20.4 0.1 0.058 13.1 0.1 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EON34588.1 - 0.0016 18.2 1.0 1.6 8.4 0.2 3.7 4 0 0 4 4 4 1 AAA domain Anti-TRAP PF15777.5 EON34588.1 - 0.0021 18.0 6.5 0.15 12.0 1.5 3.4 3 0 0 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein AAA_23 PF13476.6 EON34588.1 - 0.0027 18.2 0.0 0.37 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EON34588.1 - 0.0037 17.5 0.1 3.6 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EON34588.1 - 0.0059 16.2 0.0 6 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EON34588.1 - 0.011 15.6 0.1 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain RNA12 PF10443.9 EON34588.1 - 0.013 14.3 0.1 0.25 10.0 0.0 2.1 2 0 0 2 2 2 0 RNA12 protein AAA_18 PF13238.6 EON34588.1 - 0.014 16.0 0.9 5.8 7.5 0.1 3.7 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.13 EON34588.1 - 0.015 14.5 0.2 2.6 7.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 EON34588.1 - 0.021 14.1 0.1 3.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EON34588.1 - 0.064 13.2 1.9 29 4.5 0.1 3.7 4 0 0 4 4 4 0 NTPase Zeta_toxin PF06414.12 EON34588.1 - 0.064 12.5 0.1 0.52 9.5 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 EON34588.1 - 0.088 12.7 0.8 16 5.4 0.2 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_7 PF12775.7 EON34588.1 - 0.1 12.1 0.1 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CPT PF07931.12 EON34588.1 - 0.11 12.3 1.0 11 5.8 0.0 2.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein BCA_ABC_TP_C PF12399.8 EON34588.1 - 0.13 12.2 0.2 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter MMR_HSR1 PF01926.23 EON34588.1 - 0.15 12.1 1.5 1.9 8.6 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf_Rg PF17915.1 EON34588.1 - 0.16 11.4 3.6 6.7 6.2 0.8 3.3 3 0 0 3 3 3 0 Reverse gyrase zinc finger AAA_14 PF13173.6 EON34588.1 - 0.17 11.9 0.0 23 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain zinc_ribbon_9 PF14369.6 EON34588.1 - 0.33 11.3 2.6 36 4.7 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-TFIIB PF13453.6 EON34588.1 - 1 8.7 5.1 9.2 5.7 0.0 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 EON34588.1 - 1.7 8.2 6.4 36 4.0 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding DNA_alkylation PF08713.11 EON34590.1 - 6.5e-51 173.1 0.0 7.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme Pyr_redox_2 PF07992.14 EON34591.1 - 6.9e-54 183.1 2.9 1.1e-53 182.4 2.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON34591.1 - 1.8e-17 63.6 11.3 5.2e-15 55.8 0.8 4.2 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EON34591.1 - 8.9e-13 48.6 0.1 3.3e-12 46.8 0.0 2.0 2 0 0 2 2 1 1 Reductase C-terminal DAO PF01266.24 EON34591.1 - 2.3e-06 27.4 16.1 0.022 14.4 2.7 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EON34591.1 - 7.8e-06 26.0 9.1 0.49 10.4 0.1 4.7 4 1 1 5 5 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EON34591.1 - 0.00018 20.9 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON34591.1 - 0.00093 18.4 0.2 0.067 12.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EON34591.1 - 0.0014 17.7 12.3 0.27 10.2 2.8 3.7 3 1 1 4 4 4 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EON34591.1 - 0.0015 17.6 7.6 0.13 11.3 2.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 EON34591.1 - 0.0023 16.7 4.8 3.7 6.1 0.0 3.9 4 0 0 4 4 4 2 HI0933-like protein Amino_oxidase PF01593.24 EON34591.1 - 0.0046 16.3 0.2 0.07 12.4 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EON34591.1 - 0.0099 16.1 3.2 1.6 9.0 0.1 3.1 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.6 EON34591.1 - 0.039 14.2 1.2 0.24 11.7 0.3 3.7 5 0 0 5 5 4 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EON34591.1 - 0.045 13.8 3.3 3.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EON34591.1 - 0.13 11.6 2.1 0.58 9.5 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hen1_Lam_C PF18441.1 EON34591.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain PGM_PMM_I PF02878.16 EON34591.1 - 0.14 11.9 0.1 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I FAD_binding_3 PF01494.19 EON34591.1 - 2.7 7.1 6.8 7.5 5.7 1.0 2.4 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EON34591.1 - 3.2 6.5 7.0 2.4 6.9 0.2 2.9 2 1 1 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 EON34591.1 - 4.6 6.5 12.1 0.2 11.0 0.2 2.7 3 0 0 3 3 2 0 ThiF family DUF1589 PF07628.11 EON34592.1 - 0.043 13.9 0.9 6.4 6.9 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1589) PrgH PF09480.10 EON34593.1 - 0.01 15.2 0.6 0.013 14.9 0.6 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) BaxI_1 PF12811.7 EON34593.1 - 0.019 14.6 0.4 0.027 14.0 0.4 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DotU PF09850.9 EON34593.1 - 0.037 13.7 3.6 0.11 12.2 2.7 1.9 2 0 0 2 2 2 0 Type VI secretion system protein DotU DUF5353 PF17304.2 EON34593.1 - 0.092 12.5 0.9 0.25 11.1 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5353) RskA PF10099.9 EON34593.1 - 2.7 8.3 24.1 13 6.1 24.1 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA T_hemolysin PF12261.8 EON34594.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin DUF4307 PF14155.6 EON34595.1 - 0.0067 16.2 2.5 0.0083 15.9 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4307) VirB8 PF04335.13 EON34595.1 - 0.022 14.6 9.2 0.028 14.2 0.1 2.2 1 1 1 2 2 2 0 VirB8 protein adh_short PF00106.25 EON34596.1 - 8.1e-51 172.3 0.2 1.1e-50 171.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON34596.1 - 5.5e-41 140.7 0.2 7.4e-41 140.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON34596.1 - 5.4e-08 33.0 0.0 1.4e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON34596.1 - 0.004 16.6 0.1 0.0066 15.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TetR_N PF00440.23 EON34597.1 - 2e-15 56.3 0.4 5.2e-15 55.0 0.4 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_35 PF18556.1 EON34597.1 - 9.4e-06 25.7 0.4 2.7e-05 24.3 0.3 1.8 2 0 0 2 2 2 1 Bacterial Tetracyclin repressor, C-terminal domain HTH_7 PF02796.15 EON34597.1 - 0.0033 17.5 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_AraC PF00165.23 EON34597.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 EON34597.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 EON34597.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LacI PF00356.21 EON34597.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_8 PF02954.19 EON34597.1 - 0.044 13.6 0.1 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 EON34597.1 - 0.052 13.7 0.3 0.12 12.6 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 EON34597.1 - 0.071 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain HTH_17 PF12728.7 EON34597.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Cloacin PF03515.14 EON34597.1 - 0.098 12.3 0.0 0.24 11.1 0.0 1.3 1 1 0 1 1 1 0 Colicin-like bacteriocin tRNase domain MerR PF00376.23 EON34597.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein HbrB PF08539.11 EON34597.1 - 0.17 11.9 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 HbrB-like MR_MLE_C PF13378.6 EON34599.1 - 6.3e-28 97.9 7.3 9.8e-28 97.2 7.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like Enolase_like_N PF18374.1 EON34599.1 - 5.5e-27 92.9 1.4 1.1e-26 91.9 1.4 1.6 1 0 0 1 1 1 1 Enolase N-terminal domain-like MAAL_C PF07476.11 EON34599.1 - 0.057 12.6 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DUF2236 PF09995.9 EON34600.1 - 1.2e-45 156.5 0.1 1.5e-45 156.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) SH3_3 PF08239.11 EON34600.1 - 0.024 14.9 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Abhydrolase_1 PF00561.20 EON34601.1 - 1.3e-25 90.5 0.1 9e-22 77.9 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EON34601.1 - 2e-20 74.4 12.4 3.2e-20 73.7 12.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON34601.1 - 3.2e-18 65.9 0.2 2.1e-17 63.2 0.2 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EON34601.1 - 0.00022 20.0 0.0 0.00035 19.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 EON34601.1 - 0.033 13.9 0.1 0.45 10.2 0.0 2.1 1 1 0 2 2 2 0 PGAP1-like protein DUF1100 PF06500.11 EON34601.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF676 PF05057.14 EON34601.1 - 0.12 11.9 0.0 0.33 10.4 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 EON34601.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF915 PF06028.11 EON34601.1 - 0.12 11.6 0.0 7.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 EON34601.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 EON34601.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Esterase PF00756.20 EON34602.1 - 3.2e-25 89.2 0.4 4.4e-25 88.8 0.4 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EON34602.1 - 0.0025 17.5 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON34602.1 - 0.012 14.9 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2048 PF09752.9 EON34602.1 - 0.029 13.5 1.5 0.16 11.0 0.3 2.0 2 0 0 2 2 2 0 Abhydrolase domain containing 18 SHOCT PF09851.9 EON34603.1 - 6.9e-06 25.6 5.9 1e-05 25.1 2.6 2.3 2 0 0 2 2 2 1 Short C-terminal domain DMAP_binding PF06464.11 EON34603.1 - 0.21 12.4 0.0 0.33 11.8 0.0 1.2 1 0 0 1 1 1 0 DMAP1-binding Domain CDH PF02611.15 EON34604.1 - 1.4e-17 64.1 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase GTP_EFTU PF00009.27 EON34605.1 - 2.3e-57 193.7 0.3 3.2e-57 193.2 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EON34605.1 - 5.8e-32 110.3 0.0 1.4e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EON34605.1 - 3e-18 66.0 3.6 8.8e-18 64.5 3.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EON34605.1 - 4.8e-06 26.6 0.1 1.5e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EON34605.1 - 0.043 13.7 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EON34606.1 - 1.9e-67 226.6 0.0 3e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EON34606.1 - 2.8e-46 156.2 0.1 5.3e-46 155.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EON34606.1 - 2.3e-34 117.3 0.1 4.5e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EON34606.1 - 3.9e-31 106.9 0.1 9.7e-31 105.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EON34606.1 - 7.4e-16 58.3 1.1 7.3e-15 55.1 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EON34606.1 - 6.3e-09 35.7 0.2 1.5e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EON34606.1 - 6.2e-05 23.1 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EON34606.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family ATPgrasp_YheCD PF14398.6 EON34606.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp Ribosomal_S7 PF00177.21 EON34607.1 - 2.6e-62 208.9 0.1 2.9e-62 208.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ArgJ PF01960.18 EON34607.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 ArgJ family Ribosom_S12_S23 PF00164.25 EON34608.1 - 6.6e-43 144.9 1.3 7.5e-43 144.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 BSP PF04450.12 EON34609.1 - 0.015 15.1 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 EON34609.1 - 0.033 14.5 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Effector protein Exo_endo_phos PF03372.23 EON34610.1 - 9.2e-18 64.6 1.5 1.3e-17 64.1 1.5 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_8 PF02954.19 EON34611.1 - 4.6e-13 48.7 0.9 4.6e-13 48.7 0.9 2.0 2 0 0 2 2 1 1 Bacterial regulatory protein, Fis family AAA_16 PF13191.6 EON34611.1 - 0.00015 22.2 4.6 0.11 12.9 0.0 3.9 3 1 1 4 4 4 2 AAA ATPase domain AAA PF00004.29 EON34611.1 - 0.00088 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON34611.1 - 0.003 17.8 0.0 0.055 13.7 0.0 2.5 1 1 0 2 2 2 1 AAA domain HTH_30 PF13556.6 EON34611.1 - 0.0075 16.0 0.1 0.025 14.4 0.1 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 EON34611.1 - 0.02 15.0 0.1 0.058 13.5 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_28 PF13521.6 EON34611.1 - 0.038 14.3 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EON34611.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_22 PF13309.6 EON34611.1 - 0.074 13.1 0.1 0.23 11.5 0.1 1.8 1 1 0 1 1 1 0 HTH domain HTH_50 PF18024.1 EON34611.1 - 0.086 12.5 0.4 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EON34611.1 - 0.09 12.6 1.9 0.15 11.9 0.4 2.2 2 0 0 2 2 2 0 Homeodomain-like domain AAA_30 PF13604.6 EON34611.1 - 1.6 8.4 6.8 9.4 5.9 1.1 3.5 3 1 0 3 3 3 0 AAA domain HPP PF04982.13 EON34612.1 - 2.3e-34 118.2 17.1 5.6e-34 117.0 17.1 1.7 1 0 0 1 1 1 1 HPP family CBS PF00571.28 EON34612.1 - 1e-22 80.3 0.3 2.4e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF5437 PF17505.2 EON34612.1 - 0.42 10.7 2.5 0.44 10.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5437) Aldedh PF00171.22 EON34613.1 - 2.1e-171 570.5 0.1 2.3e-171 570.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 EON34614.1 - 2.4e-29 101.4 1.1 2.4e-29 101.4 1.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON34614.1 - 3.3e-21 75.6 2.4 6.4e-21 74.7 2.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON34614.1 - 2.2e-07 32.0 1.4 2.3e-07 31.9 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON34614.1 - 4.8e-05 22.9 2.8 7.3e-05 22.4 2.8 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PapC_C PF13953.6 EON34614.1 - 0.006 16.4 0.2 0.038 13.8 0.4 2.3 2 1 0 2 2 2 1 PapC C-terminal domain Far-17a_AIG1 PF04750.14 EON34615.1 - 0.0045 16.3 9.4 0.044 13.1 9.4 2.0 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein OAD_gamma PF04277.13 EON34615.1 - 0.036 14.6 0.0 0.074 13.7 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain COPI_assoc PF08507.10 EON34615.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.8 2 1 1 3 3 3 0 COPI associated protein DUF3040 PF11239.8 EON34615.1 - 8.3 6.8 10.4 0.61 10.4 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3040) DUF4149 PF13664.6 EON34615.1 - 8.5 6.8 9.6 0.41 11.0 3.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) TetR_N PF00440.23 EON34616.1 - 9.2e-10 38.2 0.5 2.3e-09 36.9 0.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 EON34616.1 - 0.12 12.2 0.4 0.12 12.2 0.4 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Acyl-CoA_dh_1 PF00441.24 EON34617.1 - 2.6e-29 102.4 2.0 4.7e-29 101.5 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON34617.1 - 1.2e-28 100.0 0.4 2.9e-28 98.8 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON34617.1 - 3.5e-16 59.2 0.0 6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON34617.1 - 6.1e-11 42.7 3.9 1.3e-10 41.7 3.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EON34618.1 - 1.4e-39 135.7 3.0 1.9e-39 135.2 3.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON34618.1 - 5.2e-26 91.5 0.0 1.5e-25 90.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EON34618.1 - 2.4e-25 88.5 0.1 4.4e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EON34618.1 - 1e-11 45.2 3.0 2.3e-11 44.1 3.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MDMPI_N PF11716.8 EON34619.1 - 2.2e-32 112.7 23.5 2.2e-32 112.7 23.5 1.6 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON34619.1 - 1.4e-09 38.5 7.2 2.6e-09 37.6 3.6 2.2 1 1 1 2 2 2 1 DinB superfamily DUF664 PF04978.12 EON34619.1 - 7e-06 26.5 0.9 1.1e-05 25.8 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF664) Wyosine_form PF08608.12 EON34619.1 - 1.8e-05 25.0 0.0 7.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation MDMPI_C PF07398.11 EON34619.1 - 0.12 13.2 19.9 10 7.0 19.9 3.3 1 1 0 1 1 1 0 MDMPI C-terminal domain DinB PF05163.12 EON34619.1 - 0.15 12.0 0.0 1.3 8.9 0.0 2.0 1 1 0 2 2 2 0 DinB family URO-D PF01208.17 EON34619.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) 4HBT PF03061.22 EON34620.1 - 1.5e-11 44.5 1.5 8.8e-09 35.6 0.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_3 PF13622.6 EON34620.1 - 9.9e-06 26.0 1.3 0.00046 20.5 0.1 2.1 2 0 0 2 2 2 2 Thioesterase-like superfamily AMP-binding PF00501.28 EON34622.1 - 1.2e-55 188.9 0.0 1.5e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34622.1 - 1.9e-10 41.5 0.7 4e-10 40.5 0.3 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Bac_luciferase PF00296.20 EON34623.1 - 5.6e-44 150.8 14.2 6.8e-44 150.5 14.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short_C2 PF13561.6 EON34624.1 - 2.8e-41 141.6 4.2 4.1e-40 137.8 4.2 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34624.1 - 2.8e-38 131.3 1.5 2.4e-37 128.3 1.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34624.1 - 5.9e-05 23.1 2.2 9.9e-05 22.3 1.6 1.8 1 1 1 2 2 2 1 KR domain APH PF01636.23 EON34625.1 - 1.6e-17 64.2 0.2 3.9e-17 63.0 0.3 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EON34625.1 - 3.6e-16 59.3 0.0 1.1e-13 51.2 0.0 2.3 2 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 EON34625.1 - 2.6e-12 46.4 0.0 3.8e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH_6_hur PF04655.14 EON34625.1 - 0.0073 15.7 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase RIO1 PF01163.22 EON34625.1 - 0.009 15.6 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 EON34625.1 - 0.18 10.9 0.0 0.58 9.3 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase Epimerase PF01370.21 EON34626.1 - 2.6e-29 102.4 0.0 4.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EON34626.1 - 2.8e-20 72.5 0.0 3.3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EON34626.1 - 6.3e-17 62.0 0.3 1e-16 61.3 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EON34626.1 - 9.7e-16 58.1 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EON34626.1 - 1.3e-13 50.7 0.0 4.6e-09 35.8 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 EON34626.1 - 5.4e-09 35.9 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EON34626.1 - 9.8e-06 24.9 0.1 2.9e-05 23.3 0.0 1.8 3 0 0 3 3 3 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EON34626.1 - 1.2e-05 24.6 0.0 4.8e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EON34626.1 - 0.015 15.2 0.2 0.046 13.6 0.2 1.8 1 1 0 1 1 1 0 KR domain NAD_binding_2 PF03446.15 EON34626.1 - 0.039 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EON34626.1 - 0.058 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 EON34626.1 - 0.17 11.9 2.1 17 5.3 0.3 2.8 2 1 0 2 2 2 0 Glycosyltransferase Family 4 adh_short_C2 PF13561.6 EON34627.1 - 8.6e-38 130.2 1.7 1.1e-37 129.8 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34627.1 - 1.1e-34 119.6 2.7 1.5e-34 119.2 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34627.1 - 3e-06 27.3 2.0 4.9e-06 26.6 2.0 1.3 1 0 0 1 1 1 1 KR domain SnoaL_2 PF12680.7 EON34629.1 - 0.00019 22.1 0.2 0.00024 21.7 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 EON34629.1 - 0.027 14.7 0.1 0.04 14.2 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain Fer4_15 PF13459.6 EON34630.1 - 1.1e-10 42.0 0.7 1.4e-10 41.8 0.7 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 EON34630.1 - 1.5e-08 34.5 0.0 1.7e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_13 PF13370.6 EON34630.1 - 2.8e-08 34.2 0.1 3.2e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I p450 PF00067.22 EON34631.1 - 1.2e-62 212.2 0.0 1.5e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EON34632.1 - 1.5e-40 138.7 0.1 2.3e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON34632.1 - 1.7e-30 106.3 0.7 2.2e-30 105.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON34632.1 - 5.5e-12 46.0 0.3 8.6e-12 45.3 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON34632.1 - 0.00062 19.7 2.6 0.0014 18.6 2.6 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON34632.1 - 0.001 18.6 0.1 0.002 17.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EON34632.1 - 0.043 13.4 1.1 0.078 12.5 0.8 1.5 2 0 0 2 2 2 0 NmrA-like family p450 PF00067.22 EON34633.1 - 1.6e-23 83.2 0.0 5.6e-21 74.8 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 TetR_N PF00440.23 EON34634.1 - 3.2e-13 49.2 0.9 4.9e-13 48.6 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_20 PF17925.1 EON34634.1 - 8.5e-09 35.7 0.6 2.1e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_37 PF13744.6 EON34634.1 - 0.13 12.2 0.1 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HrpF PF06266.12 EON34634.1 - 0.18 12.1 0.2 0.44 10.9 0.1 1.7 2 0 0 2 2 2 0 HrpF protein Aldedh PF00171.22 EON34635.1 - 2.5e-144 481.3 0.0 2.8e-144 481.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 EON34636.1 - 1.6e-65 221.0 1.2 1.9e-65 220.7 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34636.1 - 2.4e-45 154.4 2.2 2.9e-45 154.2 2.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34636.1 - 4.3e-06 26.7 2.4 1.2e-05 25.3 2.4 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON34636.1 - 2.3e-05 24.0 0.1 7.5e-05 22.3 0.3 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON34636.1 - 5.7e-05 23.4 0.9 9.3e-05 22.7 0.9 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EON34636.1 - 0.0071 16.6 1.9 0.028 14.7 1.5 1.9 2 0 0 2 2 2 1 TrkA-N domain Ldh_1_N PF00056.23 EON34636.1 - 0.03 14.4 1.4 0.048 13.7 1.4 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EON34636.1 - 0.051 14.1 0.9 0.092 13.3 0.5 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EON34636.1 - 0.055 12.8 0.2 0.088 12.2 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EON34637.1 - 3.3e-39 134.6 0.7 5.4e-39 133.9 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EON34637.1 - 1.4e-11 44.7 1.8 3.7e-11 43.3 0.2 2.4 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EON34637.1 - 0.00019 20.9 0.0 0.00097 18.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EON34637.1 - 0.002 17.8 0.2 0.71 9.4 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CMD PF02627.20 EON34638.1 - 1.8e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family BPD_transp_1 PF00528.22 EON34640.1 - 7.2e-23 81.3 13.0 7.2e-23 81.3 13.0 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 EON34640.1 - 0.04 14.3 2.0 0.049 14.0 0.6 1.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF4014 PF13198.6 EON34640.1 - 1.9 8.9 7.0 0.74 10.2 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4014) ABC_tran PF00005.27 EON34641.1 - 4.2e-24 85.6 0.0 7.5e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EON34641.1 - 0.00015 21.4 0.1 0.00031 20.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EON34641.1 - 0.00019 21.4 0.5 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON34641.1 - 0.01 16.2 2.7 0.028 14.8 2.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EON34641.1 - 0.017 14.7 0.3 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EON34641.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EON34641.1 - 0.04 13.4 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EON34641.1 - 0.05 13.8 0.2 0.14 12.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EON34641.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON34641.1 - 0.065 13.5 0.1 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EON34641.1 - 0.079 12.7 0.6 0.25 11.1 0.5 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EON34641.1 - 0.081 12.8 0.5 0.17 11.8 0.5 1.5 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.6 EON34641.1 - 0.12 12.6 0.6 1.2 9.4 0.6 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EON34641.1 - 0.21 12.0 0.1 0.29 11.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EON34641.1 - 0.3 10.2 0.0 0.45 9.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 EON34641.1 - 0.32 10.1 0.0 0.43 9.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit FAD_binding_2 PF00890.24 EON34642.1 - 2.2e-19 69.8 18.7 2.9e-18 66.1 8.7 3.3 2 2 1 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EON34642.1 - 1.4e-11 44.2 7.1 1.8e-08 34.0 0.1 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EON34642.1 - 9.5e-07 28.5 3.7 9.5e-07 28.5 3.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Succ_DH_flav_C PF02910.20 EON34642.1 - 5.2e-06 26.5 0.0 9.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term HI0933_like PF03486.14 EON34642.1 - 0.00016 20.5 10.7 0.00099 17.9 0.9 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 EON34642.1 - 0.00096 18.5 1.7 0.36 10.0 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EON34642.1 - 0.0082 16.7 0.6 17 6.1 0.2 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EON34642.1 - 0.017 14.4 0.8 0.047 13.0 0.8 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EON34642.1 - 0.056 12.7 1.5 0.13 11.5 0.9 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EON34642.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 EON34642.1 - 2.7 7.0 7.4 0.098 11.7 0.5 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Fer4 PF00037.27 EON34643.1 - 2.3e-08 33.5 11.2 1.4e-05 24.7 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EON34643.1 - 1.3e-07 32.1 13.4 2.5e-07 31.2 13.6 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EON34643.1 - 1.6e-07 31.4 11.5 2.1e-07 31.0 11.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON34643.1 - 6.9e-07 29.1 14.1 0.00012 22.0 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EON34643.1 - 2.7e-06 28.2 9.5 0.0012 19.7 1.9 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EON34643.1 - 4.2e-06 26.8 11.6 7.2e-06 26.0 11.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EON34643.1 - 7.9e-06 26.3 7.0 0.0081 16.7 1.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON34643.1 - 1.4e-05 25.2 13.2 0.00058 20.2 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EON34643.1 - 4.6e-05 23.5 12.3 8.9e-05 22.6 12.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EON34643.1 - 0.0016 18.4 4.4 0.0016 18.4 4.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 EON34643.1 - 0.016 15.6 16.3 0.24 11.9 4.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EON34643.1 - 0.019 15.9 17.0 0.16 13.0 5.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 EON34643.1 - 0.067 13.7 14.9 2.1 8.9 14.9 2.2 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EON34643.1 - 0.11 12.7 13.3 0.14 12.3 3.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EON34643.1 - 0.28 12.1 8.3 0.92 10.4 1.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EON34643.1 - 0.43 11.4 11.6 1.6e+02 3.1 11.6 2.3 1 1 0 1 1 1 0 4Fe-4S single cluster domain DUF3079 PF11278.8 EON34643.1 - 3.5 7.5 9.6 0.17 11.8 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3079) NMT1 PF09084.11 EON34644.1 - 1.4e-11 44.8 0.0 1.9e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON34644.1 - 6e-08 32.7 0.0 2.3e-07 30.8 0.0 1.9 2 1 0 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.20 EON34644.1 - 1e-07 31.7 0.0 3.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON34644.1 - 0.0001 22.0 0.0 0.00031 20.4 0.0 1.7 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Bac_luciferase PF00296.20 EON34645.1 - 4.9e-67 226.6 5.8 6.2e-67 226.2 5.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2048 PF09752.9 EON34646.1 - 7.2e-08 31.9 0.1 1.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 EON34646.1 - 0.0013 19.4 4.7 0.0013 19.4 4.7 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EON34646.1 - 0.0013 18.6 0.4 0.0028 17.6 0.4 1.4 1 1 0 1 1 1 1 Serine hydrolase UPF0227 PF05728.12 EON34646.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) AXE1 PF05448.12 EON34646.1 - 0.0022 16.7 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EON34646.1 - 0.0042 16.4 1.2 0.98 8.6 0.5 2.9 1 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EON34646.1 - 0.013 15.4 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON34646.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 EON34646.1 - 0.044 13.7 0.1 0.083 12.8 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 EON34646.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein WES_acyltransf PF03007.16 EON34647.1 - 1.6e-47 162.5 9.7 2.8e-47 161.7 9.7 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON34647.1 - 2.1e-14 53.7 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) AMP-binding PF00501.28 EON34648.1 - 1.2e-63 215.2 0.0 1.5e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34648.1 - 4.1e-19 69.3 0.1 1.2e-18 67.8 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyltransferase PF01553.21 EON34649.1 - 9.1e-12 44.7 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 EON34649.1 - 2.4e-07 30.0 0.0 2.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase 4HBT PF03061.22 EON34650.1 - 0.00013 22.2 0.2 0.00025 21.3 0.2 1.5 1 0 0 1 1 1 1 Thioesterase superfamily PqqD PF05402.12 EON34650.1 - 0.18 12.1 0.4 0.31 11.4 0.4 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) ADH_N PF08240.12 EON34651.1 - 1.7e-21 76.2 1.5 4.5e-21 74.8 0.1 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON34651.1 - 4.3e-13 49.4 0.1 7.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON34651.1 - 2.2e-11 43.6 0.3 4.3e-11 42.7 0.3 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON34651.1 - 2.7e-06 28.4 0.0 6.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EON34651.1 - 0.031 13.6 0.3 0.059 12.7 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_2 PF04909.14 EON34652.1 - 2e-30 106.6 2.9 2.3e-30 106.4 2.9 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EON34652.1 - 0.025 13.9 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase family ABC_tran PF00005.27 EON34653.1 - 3.3e-37 128.1 0.0 4.5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34653.1 - 2.7e-09 37.3 0.0 0.00081 19.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34653.1 - 9.5e-09 35.0 0.1 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON34653.1 - 2.4e-05 24.0 0.0 5.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON34653.1 - 5.7e-05 23.6 0.1 9.1e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EON34653.1 - 9e-05 22.8 0.0 0.0004 20.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON34653.1 - 0.00025 20.8 0.1 0.0005 19.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EON34653.1 - 0.0018 18.8 0.0 0.0038 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON34653.1 - 0.002 18.0 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 EON34653.1 - 0.0072 16.5 0.5 0.1 12.8 0.5 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EON34653.1 - 0.0078 16.2 0.1 0.6 10.1 0.0 2.9 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EON34653.1 - 0.01 16.2 0.0 0.84 10.1 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EON34653.1 - 0.012 14.4 0.5 1.2 7.8 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 EON34653.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 EON34653.1 - 0.028 14.2 0.0 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EON34653.1 - 0.051 13.7 0.1 0.076 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Resolvase PF00239.21 EON34653.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_23 PF13476.6 EON34653.1 - 0.071 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EON34653.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.6 EON34653.1 - 0.081 11.6 0.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EON34653.1 - 0.12 12.0 1.4 0.59 9.7 1.4 2.3 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EON34653.1 - 0.15 10.9 0.2 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein G-alpha PF00503.20 EON34653.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SBP_bac_3 PF00497.20 EON34654.1 - 1.5e-43 148.8 0.1 2e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 EON34654.1 - 2.2e-26 92.7 7.4 2.2e-26 92.7 7.4 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Lig_chan-Glu_bd PF10613.9 EON34654.1 - 6e-05 23.2 0.0 0.0003 21.0 0.0 1.9 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site BCA_ABC_TP_C PF12399.8 EON34654.1 - 0.12 12.3 0.3 6.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DUF2277 PF10041.9 EON34655.1 - 1e-35 121.9 1.3 1.1e-35 121.7 1.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) DUF4663 PF15668.5 EON34655.1 - 0.074 12.1 0.3 0.077 12.1 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) ADH_zinc_N PF00107.26 EON34656.1 - 1e-25 90.2 0.2 1.6e-25 89.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EON34656.1 - 3.2e-14 54.1 0.3 2.1e-13 51.5 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EON34656.1 - 5.2e-12 45.6 0.2 2.4e-11 43.5 0.2 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EON34656.1 - 0.0018 17.6 1.5 0.0044 16.4 1.5 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 EON34656.1 - 0.0032 17.6 0.7 0.0099 16.0 0.7 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EON34656.1 - 0.023 14.1 0.3 0.035 13.5 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 EON34656.1 - 0.067 13.0 0.6 0.16 11.7 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.18 EON34656.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_24 PF13578.6 EON34657.1 - 6.1e-20 72.2 0.5 9.5e-20 71.6 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EON34658.1 - 2.7e-60 203.8 2.1 3.2e-60 203.6 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34658.1 - 4.1e-44 150.4 2.2 5.2e-44 150.0 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EON34658.1 - 2.5e-09 37.0 0.4 3.4e-09 36.5 0.4 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EON34658.1 - 4.8e-08 33.3 1.0 6.9e-08 32.8 1.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EON34658.1 - 1.2e-07 31.9 1.6 1.9e-07 31.2 1.6 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON34658.1 - 1.8e-06 28.0 2.8 2.7e-06 27.4 2.8 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EON34658.1 - 0.00013 22.2 1.0 0.00022 21.5 1.0 1.3 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 EON34658.1 - 0.0034 16.8 0.1 0.0043 16.5 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EON34658.1 - 0.0049 16.9 0.1 0.0068 16.5 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 EON34658.1 - 0.0049 16.4 2.1 0.007 15.9 2.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EON34658.1 - 0.0061 15.7 0.3 0.0089 15.2 0.3 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N PF00107.26 EON34658.1 - 0.038 14.0 1.9 0.08 12.9 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 EON34658.1 - 0.23 10.4 0.4 0.28 10.1 0.4 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Hydrolase_4 PF12146.8 EON34659.1 - 1.1e-14 54.3 0.9 1.7e-14 53.7 0.9 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EON34659.1 - 5.4e-11 41.7 0.7 9e-06 24.6 0.3 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EON34659.1 - 5.7e-10 40.2 10.4 8.5e-10 39.6 10.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EON34659.1 - 1.9e-09 37.6 0.1 1.9e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EON34659.1 - 2.5e-06 27.1 1.8 4.5e-06 26.3 0.8 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EON34659.1 - 6.3e-06 26.0 0.6 8.9e-06 25.5 0.6 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EON34659.1 - 0.00018 21.2 0.8 0.002 17.7 0.1 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family FMO-like PF00743.19 EON34660.1 - 7.5e-75 252.3 0.0 9.6e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EON34660.1 - 1.4e-17 63.9 0.0 6.9e-15 55.1 0.0 2.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34660.1 - 1.7e-08 34.6 0.0 4.5e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EON34660.1 - 5.3e-08 32.5 0.0 6.8e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EON34660.1 - 1.2e-06 28.0 0.0 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EON34660.1 - 7.7e-05 23.2 0.0 0.046 14.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON34660.1 - 0.00031 20.7 0.1 0.025 14.6 0.1 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EON34660.1 - 0.0019 17.9 0.1 1.2 8.7 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EON34660.1 - 0.01 15.2 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EON34660.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EON34660.1 - 0.13 11.5 0.3 0.27 10.5 0.1 1.5 2 0 0 2 2 2 0 Thi4 family TetR_N PF00440.23 EON34661.1 - 1.3e-13 50.5 0.0 2.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 EON34661.1 - 0.0062 16.8 0.5 0.0062 16.8 0.5 1.9 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 EON34661.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_26 PF13443.6 EON34661.1 - 0.03 14.8 0.1 0.078 13.4 0.0 1.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain LacI PF00356.21 EON34661.1 - 0.27 11.0 0.5 0.8 9.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Bac_luciferase PF00296.20 EON34662.1 - 9.9e-48 163.2 2.8 1.3e-47 162.8 2.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TENA_THI-4 PF03070.16 EON34663.1 - 4.3e-34 118.2 0.0 5.8e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family NMT1 PF09084.11 EON34664.1 - 8.3e-58 195.9 0.0 1.1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON34664.1 - 6.6e-05 22.7 0.1 0.033 13.9 0.0 2.2 2 0 0 2 2 2 2 NMT1-like family SBP_bac_3 PF00497.20 EON34664.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Big_3_5 PF16640.5 EON34664.1 - 0.063 13.5 2.7 0.66 10.2 0.2 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) OpuAC PF04069.12 EON34664.1 - 0.11 12.0 0.8 5.7 6.4 0.0 2.5 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 EON34665.1 - 2.3e-24 86.2 20.8 2.3e-24 86.2 20.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 EON34665.1 - 0.0033 17.9 1.5 0.0033 17.9 1.5 3.4 2 1 2 4 4 4 1 FtsX-like permease family CbiN PF02553.15 EON34665.1 - 0.37 10.8 0.0 0.37 10.8 0.0 2.4 3 0 0 3 3 3 0 Cobalt transport protein component CbiN ABC_tran PF00005.27 EON34666.1 - 1.5e-28 100.0 0.0 2.2e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EON34666.1 - 1.9e-05 25.1 0.1 3.4e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EON34666.1 - 0.0017 18.6 0.0 0.0067 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON34666.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EON34666.1 - 0.0076 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EON34666.1 - 0.0078 16.5 0.0 0.026 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EON34666.1 - 0.0097 15.7 0.2 0.44 10.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EON34666.1 - 0.031 14.5 0.3 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EON34666.1 - 0.044 13.2 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EON34666.1 - 0.058 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EON34666.1 - 0.071 12.7 0.2 0.55 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EON34666.1 - 0.11 11.6 0.1 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Bac_rhamnosid6H PF17389.2 EON34667.1 - 0.0032 16.8 0.1 0.0048 16.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Prenyltrans PF00432.21 EON34667.1 - 0.0037 17.0 0.0 0.032 14.0 0.0 2.4 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat DUF608 PF04685.13 EON34667.1 - 0.0061 15.8 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region SQHop_cyclase_N PF13249.6 EON34667.1 - 0.0095 15.1 0.2 1.5 7.8 0.0 2.5 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain TPR_16 PF13432.6 EON34667.1 - 0.02 15.5 0.1 2.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EON34667.1 - 0.13 12.9 2.7 1.1 10.1 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EON34668.1 - 2.4e-19 69.7 0.0 1.3e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EON34668.1 - 1.2e-16 61.1 0.1 3.8e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EON34668.1 - 1.4e-16 60.7 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EON34668.1 - 3.4e-15 56.2 0.0 7.4e-15 55.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EON34668.1 - 5.3e-10 39.9 0.0 2.2e-09 37.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EON34668.1 - 5.1e-09 35.8 0.0 8.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EON34668.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EON34668.1 - 0.0021 17.7 0.0 0.0044 16.6 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 EON34668.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 EON34668.1 - 0.0065 16.3 0.0 0.19 11.5 0.0 2.1 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EON34668.1 - 0.0095 14.5 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribonuc_red_lgN PF00317.21 EON34668.1 - 0.17 11.9 0.3 0.36 10.9 0.3 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Glyco_trans_1_4 PF13692.6 EON34669.1 - 3.3e-28 98.8 0.1 6.9e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EON34669.1 - 9.3e-28 96.9 0.0 2.1e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EON34669.1 - 7.4e-25 87.9 0.6 5.5e-24 85.1 0.6 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EON34669.1 - 1.9e-21 77.2 3.2 3.3e-21 76.4 0.3 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EON34669.1 - 1.4e-11 44.6 0.0 3.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 EON34669.1 - 0.024 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Pyr_redox_2 PF07992.14 EON34670.1 - 2.6e-13 49.9 1.1 8.1e-11 41.7 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 EON34670.1 - 1.4e-07 31.0 7.0 1.4e-07 31.0 7.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 EON34670.1 - 6.7e-06 26.6 5.3 1.3e-05 25.7 5.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON34670.1 - 1.4e-05 24.9 5.2 3.6e-05 23.6 5.2 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_10 PF13237.6 EON34670.1 - 2.6e-05 24.2 0.3 5.2e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EON34670.1 - 5.4e-05 23.1 3.2 0.00012 21.9 3.2 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_16 PF13484.6 EON34670.1 - 0.00013 22.8 0.4 0.00013 22.8 0.4 2.3 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EON34670.1 - 0.001 19.2 3.9 0.0018 18.4 3.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 EON34670.1 - 0.0014 18.9 2.1 0.0032 17.9 2.1 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain NAD_binding_9 PF13454.6 EON34670.1 - 0.0017 18.4 0.0 0.0042 17.1 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 EON34670.1 - 0.0023 17.2 0.2 0.045 13.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 EON34670.1 - 0.0026 18.0 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_8 PF13183.6 EON34670.1 - 0.0036 17.7 0.1 0.0076 16.7 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EON34670.1 - 0.0037 17.4 0.8 0.0037 17.4 0.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain NAD_binding_7 PF13241.6 EON34670.1 - 0.0091 16.4 1.6 0.61 10.5 0.1 3.3 3 1 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EON34670.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EON34670.1 - 0.01 16.3 0.0 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.6 EON34670.1 - 0.014 16.0 0.2 0.026 15.0 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Nsp3_PL2pro PF12124.8 EON34670.1 - 0.022 14.5 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Shikimate_DH PF01488.20 EON34670.1 - 0.064 13.3 0.0 9.5 6.3 0.0 2.9 3 1 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 EON34670.1 - 0.096 11.9 0.3 6.4 5.9 0.1 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EON34670.1 - 0.11 11.1 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Fer4_15 PF13459.6 EON34670.1 - 2 9.2 8.6 0.18 12.6 0.6 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EON34670.1 - 2.4 8.8 13.4 0.36 11.4 5.6 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Acyl-ACP_TE PF01643.17 EON34671.1 - 5.4e-27 94.7 0.0 7.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT PF03061.22 EON34671.1 - 0.11 12.8 0.6 1.4e+02 3.0 0.0 3.9 3 1 1 4 4 4 0 Thioesterase superfamily 4HBT_2 PF13279.6 EON34671.1 - 0.17 12.4 0.7 1.2 9.6 0.0 2.5 2 2 0 2 2 2 0 Thioesterase-like superfamily DUF3558 PF12079.8 EON34672.1 - 2.9e-29 102.3 0.4 3.3e-29 102.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) DUF4307 PF14155.6 EON34672.1 - 0.013 15.3 0.2 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF3558 PF12079.8 EON34673.1 - 1.8e-30 106.3 0.6 2.5e-30 105.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) S4 PF01479.25 EON34673.1 - 1.3e-10 40.8 0.0 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain RskA PF10099.9 EON34673.1 - 0.0077 16.6 2.1 0.014 15.7 2.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Insulin_TMD PF17870.1 EON34674.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Amidase PF01425.21 EON34676.1 - 7.2e-70 236.2 3.5 9.2e-70 235.8 3.5 1.1 1 0 0 1 1 1 1 Amidase GGACT PF06094.12 EON34676.1 - 0.032 14.9 0.0 0.068 13.8 0.0 1.6 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like CT_A_B PF02626.15 EON34677.1 - 2.5e-90 302.7 0.1 3.5e-90 302.2 0.1 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 EON34677.1 - 1.6e-48 165.1 0.0 2.3e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D SAM_PNT PF02198.16 EON34677.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF1989 PF09347.10 EON34678.1 - 2.9e-57 192.9 0.0 3.5e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF1989 PF09347.10 EON34679.1 - 3.4e-42 143.9 0.0 4.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF3054 PF11255.8 EON34679.1 - 0.027 15.0 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) AA_permease_2 PF13520.6 EON34680.1 - 3.2e-41 141.6 36.9 3.9e-41 141.3 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EON34680.1 - 1.9e-24 86.1 29.9 1.9e-24 86.1 29.9 2.0 1 1 1 2 2 2 1 Amino acid permease Sdh_cyt PF01127.22 EON34680.1 - 3.9 7.5 19.3 1.1 9.4 0.1 3.9 3 1 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TetR_N PF00440.23 EON34681.1 - 4e-17 61.8 0.3 8e-17 60.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family AMP-binding PF00501.28 EON34683.1 - 0 1337.0 9.0 7e-89 298.3 0.2 5.5 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 EON34683.1 - 0 1330.1 0.0 6.5e-92 308.6 0.0 6.1 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EON34683.1 - 2.4e-65 216.8 13.5 5.8e-13 49.0 0.2 6.5 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EON34683.1 - 1.8e-46 157.0 11.5 7.1e-10 39.7 0.0 6.3 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EON34683.1 - 8.6e-27 94.7 0.0 3.9e-26 92.6 0.0 2.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EON34683.1 - 0.036 13.7 0.1 0.083 12.5 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EON34683.1 - 0.084 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MarR PF01047.22 EON34684.1 - 1.4e-09 37.8 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EON34684.1 - 1.3e-08 34.6 0.2 2.5e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EON34684.1 - 3.3e-08 33.9 0.1 5.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 EON34684.1 - 0.00025 21.0 0.3 0.00053 20.0 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.27 EON34684.1 - 0.0019 18.1 0.3 0.011 15.7 0.2 2.2 1 1 1 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 EON34684.1 - 0.003 17.7 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 EON34684.1 - 0.0037 17.0 2.0 0.014 15.2 0.3 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_28 PF13518.6 EON34684.1 - 0.0049 17.0 0.2 0.049 13.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 EON34684.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family HTH_47 PF16221.5 EON34684.1 - 0.018 14.6 0.0 0.33 10.5 0.0 2.3 2 1 0 2 2 2 0 winged helix-turn-helix HTH_24 PF13412.6 EON34684.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EON34684.1 - 0.034 14.0 1.5 0.038 13.8 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain TrmB PF01978.19 EON34684.1 - 0.073 13.0 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_30 PF13556.6 EON34684.1 - 0.079 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_29 PF13551.6 EON34684.1 - 0.097 12.7 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix AbiEi_4 PF13338.6 EON34685.1 - 2.3e-09 37.2 1.6 1.1e-08 35.1 0.3 2.5 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin MTES_1575 PF18741.1 EON34685.1 - 3.3e-09 36.8 0.0 5.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 EON34685.1 - 1.4e-08 34.5 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF559) AbiEi_1 PF09407.10 EON34685.1 - 0.00026 21.3 0.9 0.00051 20.4 0.5 1.7 2 0 0 2 2 2 1 AbiEi antitoxin C-terminal domain DUF2726 PF10881.8 EON34685.1 - 0.039 13.8 0.2 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) RAP PF08373.10 EON34685.1 - 0.19 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 RAP domain NAD_binding_2 PF03446.15 EON34686.1 - 1.2e-47 162.0 0.7 1.8e-47 161.4 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EON34686.1 - 2.2e-38 131.2 0.3 4.3e-38 130.3 0.3 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EON34686.1 - 1.1e-08 35.5 0.2 3.1e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EON34686.1 - 0.0002 21.0 0.2 0.00042 19.9 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EON34686.1 - 0.00065 19.6 0.1 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EON34686.1 - 0.0052 16.4 0.0 0.031 13.8 0.0 2.0 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EON34686.1 - 0.0061 15.9 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EON34686.1 - 0.0072 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 EON34686.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_1 PF00441.24 EON34687.1 - 8.7e-48 162.3 1.5 1.4e-47 161.7 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON34687.1 - 2.7e-25 88.4 0.0 5.1e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON34687.1 - 5.8e-25 88.1 0.0 1.5e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON34687.1 - 6.2e-19 68.6 4.0 7.6e-19 68.3 1.9 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Aldedh PF00171.22 EON34688.1 - 1.3e-141 472.3 0.0 1.6e-141 472.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EON34688.1 - 0.0098 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) PE PF00934.20 EON34688.1 - 0.054 13.8 1.2 0.13 12.6 1.2 1.6 1 0 0 1 1 1 0 PE family Lycopene_cycl PF05834.12 EON34688.1 - 0.12 11.4 0.2 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Flavodoxin_1 PF00258.25 EON34689.1 - 1.1e-29 103.5 0.0 1.3e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EON34689.1 - 0.0009 19.5 0.0 0.0013 19.0 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 EON34689.1 - 0.0055 16.4 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain PhoLip_ATPase_C PF16212.5 EON34690.1 - 0.013 15.3 2.6 0.027 14.2 2.6 1.4 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF3087 PF11286.8 EON34690.1 - 0.024 14.1 1.9 1.9 8.0 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) YfhO PF09586.10 EON34690.1 - 0.065 11.5 1.4 0.42 8.8 0.1 2.0 1 1 1 2 2 2 0 Bacterial membrane protein YfhO BaxI_1 PF12811.7 EON34690.1 - 3.1 7.3 18.1 1.7 8.1 14.1 2.5 1 1 1 2 2 2 0 Bax inhibitor 1 like His_Phos_1 PF00300.22 EON34692.1 - 6e-09 35.9 0.1 2.1e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) NAD_synthase PF02540.17 EON34693.1 - 2e-66 223.6 0.0 2.3e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 NAD synthase NAD_synthase PF02540.17 EON34694.1 - 2.8e-23 82.3 0.0 4.3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 EON34694.1 - 1e-16 61.1 0.0 1.5e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WES_acyltransf PF03007.16 EON34695.1 - 3.4e-77 259.8 1.3 4.7e-77 259.3 0.4 1.6 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 EON34695.1 - 4.9e-27 94.7 0.0 1.1e-26 93.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Pkinase PF00069.25 EON34697.1 - 3e-40 138.3 0.0 4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON34697.1 - 2.2e-23 82.8 0.0 3.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON34697.1 - 4.2e-06 26.9 1.2 0.088 12.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON34697.1 - 0.0074 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase SnoaL_2 PF12680.7 EON34698.1 - 4.2e-09 37.0 1.3 7.7e-09 36.1 1.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EON34698.1 - 2.3e-06 27.8 0.4 3.1e-06 27.4 0.4 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EON34698.1 - 0.0001 22.7 0.4 0.00017 21.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EON34698.1 - 0.0005 20.3 1.1 0.0011 19.3 0.4 1.9 1 1 1 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 EON34698.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase FA_desaturase_2 PF03405.14 EON34699.1 - 1.9e-80 270.1 0.5 2.3e-80 269.9 0.5 1.0 1 0 0 1 1 1 1 Fatty acid desaturase BING4CT PF08149.11 EON34699.1 - 0.018 14.8 0.1 5.4 6.9 0.1 2.6 3 0 0 3 3 3 0 BING4CT (NUC141) domain MycE_N PF17843.1 EON34699.1 - 0.078 13.5 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 MycE methyltransferase N-terminal Dus PF01207.17 EON34700.1 - 1.9e-104 349.1 0.0 2.3e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-HC2 PF13490.6 EON34700.1 - 0.023 14.9 0.0 4.9 7.5 0.0 2.9 2 0 0 2 2 2 0 Putative zinc-finger FMN_dh PF01070.18 EON34700.1 - 0.026 13.6 0.0 0.058 12.4 0.0 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase LytR_cpsA_psr PF03816.14 EON34701.1 - 4.2e-41 140.6 0.0 2e-40 138.5 0.0 2.0 2 0 0 2 2 2 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 EON34701.1 - 4.8e-17 62.7 0.6 4.8e-17 62.7 0.6 2.0 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator PhoU PF01895.19 EON34702.1 - 1.8e-22 79.6 1.4 5e-10 39.7 0.1 2.1 2 0 0 2 2 2 2 PhoU domain ABC_tran PF00005.27 EON34704.1 - 3e-30 105.5 0.0 4.9e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34704.1 - 3.4e-10 40.2 0.0 0.00058 19.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34704.1 - 1.3e-05 24.7 0.0 0.00015 21.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EON34704.1 - 0.00044 20.2 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EON34704.1 - 0.00064 20.0 0.0 0.0012 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EON34704.1 - 0.00083 19.1 0.0 0.0031 17.2 0.0 1.9 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON34704.1 - 0.0014 19.1 0.1 0.0038 17.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EON34704.1 - 0.0025 17.6 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EON34704.1 - 0.004 17.1 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EON34704.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EON34704.1 - 0.019 15.4 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON34704.1 - 0.022 14.5 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EON34704.1 - 0.022 14.9 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EON34704.1 - 0.047 13.9 0.2 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EON34704.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EON34704.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase BPD_transp_1 PF00528.22 EON34705.1 - 1.9e-26 92.9 15.9 1.9e-26 92.9 15.9 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Tautomerase PF01361.21 EON34705.1 - 0.13 12.2 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Tautomerase enzyme TssN PF17555.2 EON34705.1 - 0.15 11.4 1.5 0.32 10.3 1.5 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF3333 PF11812.8 EON34705.1 - 1.3 9.2 4.2 0.35 11.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DUF5316 PF17247.2 EON34705.1 - 6.1 6.9 6.7 1 9.4 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5316) BPD_transp_1 PF00528.22 EON34706.1 - 6.4e-16 58.6 17.4 6.4e-16 58.6 17.4 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PBP_like_2 PF12849.7 EON34707.1 - 3.4e-50 171.3 3.1 4.7e-50 170.8 3.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EON34707.1 - 6e-10 38.6 0.0 1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain Metal_resist PF13801.6 EON34708.1 - 3.8 7.7 12.5 4.1 7.6 1.0 3.0 3 0 0 3 3 3 0 Heavy-metal resistance Glycos_transf_2 PF00535.26 EON34709.1 - 5.1e-18 65.5 0.0 7.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON34709.1 - 2.8e-13 50.3 0.8 1.1e-12 48.3 0.7 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EON34709.1 - 1e-06 28.4 0.0 2.4e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EON34709.1 - 0.0021 17.6 0.0 0.0083 15.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON34709.1 - 0.057 13.3 0.2 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family group 2 MEDS PF14417.6 EON34709.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain XdhC_CoxI PF02625.16 EON34709.1 - 0.15 12.3 0.4 0.15 12.3 0.4 2.4 3 0 0 3 3 3 0 XdhC and CoxI family NTP_transf_3 PF12804.7 EON34709.1 - 0.16 12.3 4.4 0.034 14.5 1.0 1.6 2 0 0 2 2 2 0 MobA-like NTP transferase domain Glyco_hydro_16 PF00722.21 EON34710.1 - 6e-21 74.7 0.0 7.6e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EON34710.1 - 3.4e-06 25.8 0.0 0.014 13.8 0.0 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glycos_transf_2 PF00535.26 EON34711.1 - 2.3e-24 86.1 0.0 3.5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON34711.1 - 3.6e-17 63.0 0.0 5.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON34711.1 - 9.3e-08 31.9 0.0 4.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EON34711.1 - 3.9e-06 26.9 0.1 7.1e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EON34711.1 - 0.00018 21.0 0.1 0.0076 15.7 0.0 2.9 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EON34713.1 - 8.6e-20 71.2 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EON34713.1 - 1.9e-07 31.2 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EON34713.1 - 0.066 12.7 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF2678 PF10856.8 EON34714.1 - 0.66 9.9 3.8 0.53 10.2 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) AMP-binding PF00501.28 EON34715.1 - 5.9e-42 143.7 0.0 8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EON34715.1 - 7.5e-19 68.8 0.0 3.6e-18 66.5 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 EON34715.1 - 6.6e-11 43.0 0.0 1.8e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 EON34715.1 - 3.9e-08 34.2 8.0 3.9e-08 34.2 8.0 3.8 3 1 0 4 4 4 1 Alpha/beta hydrolase family PP-binding PF00550.25 EON34715.1 - 2e-06 28.1 0.1 5e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 EON34715.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EON34715.1 - 0.00053 19.9 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 EON34715.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EON34715.1 - 0.0061 16.2 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EON34715.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EON34715.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Acetyltransf_1 PF00583.25 EON34716.1 - 4.5e-20 72.0 0.2 9.4e-14 51.7 0.1 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EON34716.1 - 5.8e-14 52.3 0.0 6.8e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EON34716.1 - 2.8e-12 46.4 0.1 2e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 EON34716.1 - 8.1e-11 42.0 0.0 9.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EON34716.1 - 4.4e-05 23.5 0.3 0.27 11.4 0.0 2.8 3 1 0 3 3 3 2 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EON34716.1 - 0.00023 21.9 0.0 0.0065 17.1 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EON34716.1 - 0.00061 20.0 3.3 0.001 19.2 0.4 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EON34716.1 - 0.00089 19.3 0.1 2.9 8.0 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Trans_reg_C PF00486.28 EON34717.1 - 1.4e-28 98.8 0.0 2.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 EON34717.1 - 0.18 11.3 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF2993 PF11209.8 EON34718.1 - 3.8e-23 82.9 4.1 4.6e-23 82.6 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Rhodanese PF00581.20 EON34719.1 - 3.1e-38 130.6 0.5 2.1e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF1416 PF07210.12 EON34720.1 - 2.1e-43 146.1 0.1 2.4e-43 146.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1416) CarboxypepD_reg PF13620.6 EON34720.1 - 2.6e-10 40.4 0.5 3.7e-10 39.9 0.5 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 EON34720.1 - 0.0036 17.6 0.3 0.0063 16.8 0.3 1.4 1 1 0 1 1 1 1 Invasin, domain 3 bMG3 PF11974.8 EON34720.1 - 0.0097 15.9 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain DUF1069 PF06370.11 EON34720.1 - 0.021 14.5 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Dioxygenase_C PF00775.21 EON34720.1 - 0.026 14.0 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase Big_1 PF02369.16 EON34720.1 - 0.033 14.2 0.4 0.14 12.2 0.4 2.1 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) Big_6 PF17936.1 EON34720.1 - 0.048 13.9 0.2 0.095 13.0 0.2 1.7 1 1 0 1 1 1 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EON34720.1 - 0.097 12.8 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase SdrD_B PF17210.3 EON34720.1 - 0.097 12.9 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain Big_3_5 PF16640.5 EON34720.1 - 0.1 12.8 3.1 1.2 9.3 3.1 2.0 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) TRIQK PF15168.6 EON34721.1 - 0.26 11.2 2.5 0.25 11.3 2.5 1.1 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family CoxIIa PF08113.11 EON34721.1 - 0.39 10.6 5.6 0.5 10.2 5.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family DUF1794 PF08768.11 EON34722.1 - 3.6e-45 153.6 0.1 4.5e-45 153.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) E1-E2_ATPase PF00122.20 EON34724.1 - 9.5e-47 158.8 4.5 9.5e-47 158.8 4.5 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EON34724.1 - 1e-42 146.8 4.8 1e-42 146.8 4.8 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON34724.1 - 7.5e-06 25.9 0.1 0.0013 18.5 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON34724.1 - 2.7e-05 24.7 1.3 0.00013 22.4 0.8 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UL45 PF05473.12 EON34725.1 - 0.043 13.5 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1953 PF09196.10 EON34725.1 - 0.085 12.7 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1953) DUF1218 PF06749.12 EON34726.1 - 0.023 15.2 0.5 0.043 14.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) AdoHcyase PF05221.17 EON34726.1 - 0.046 12.9 0.1 0.062 12.4 0.1 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase DUF3810 PF12725.7 EON34726.1 - 0.078 12.3 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Mid2 PF04478.12 EON34726.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3040 PF11239.8 EON34726.1 - 1.4 9.3 3.7 4.2 7.7 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) MlaD PF02470.20 EON34727.1 - 2e-14 53.6 0.2 4.9e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 MlaD protein FLgD_tudor PF13861.6 EON34727.1 - 0.17 12.1 3.1 0.52 10.6 0.4 2.6 2 1 0 2 2 2 0 FlgD Tudor-like domain Mce4_CUP1 PF11887.8 EON34728.1 - 6.8e-11 42.1 0.4 9.8e-11 41.6 0.4 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 EON34728.1 - 3.3e-09 36.9 0.1 6.6e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 MlaD protein MlaD PF02470.20 EON34729.1 - 7.6e-16 58.2 0.7 1.7e-15 57.1 0.7 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON34729.1 - 4.5e-08 32.9 1.7 6.7e-08 32.3 1.7 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 EON34729.1 - 0.00024 21.1 3.6 0.0053 16.8 3.0 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EON34729.1 - 0.00048 20.5 1.2 0.16 12.4 0.0 3.3 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF885 PF05960.11 EON34729.1 - 0.049 13.3 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Syntaxin-6_N PF09177.11 EON34729.1 - 0.068 13.7 0.5 0.32 11.6 0.4 2.0 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Serine_rich PF08824.10 EON34729.1 - 0.11 12.5 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 Serine rich protein interaction domain DASH_Dam1 PF08653.10 EON34729.1 - 0.23 11.3 0.6 9.2 6.2 0.1 2.8 1 1 1 2 2 2 0 DASH complex subunit Dam1 MlaD PF02470.20 EON34730.1 - 2.8e-16 59.6 0.8 6.1e-16 58.5 0.8 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON34730.1 - 0.00037 20.0 1.8 0.00054 19.5 1.8 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 EON34730.1 - 0.015 15.5 5.0 1.3 9.3 0.1 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 EON34730.1 - 0.066 12.2 0.3 0.17 10.8 0.1 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 EON34730.1 - 0.21 12.1 0.9 0.97 9.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DHR10 PF18595.1 EON34730.1 - 0.91 9.6 3.1 1 9.4 0.5 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 EON34730.1 - 1.4 9.0 9.0 4.1 7.4 0.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MlaD PF02470.20 EON34731.1 - 1.4e-15 57.3 0.1 2.9e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 EON34731.1 - 0.017 14.6 2.3 0.033 13.7 2.3 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Spc7 PF08317.11 EON34731.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EON34731.1 - 1.7 8.7 11.3 5.7 7.0 10.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mce4_CUP1 PF11887.8 EON34732.1 - 3.6e-48 164.3 0.3 4.6e-48 163.9 0.3 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 EON34732.1 - 7.4e-11 42.2 0.2 1.3e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 MlaD protein DinB_2 PF12867.7 EON34732.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 DinB superfamily Baculo_PEP_C PF04513.12 EON34732.1 - 1.5 8.9 8.3 24 5.0 8.5 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MlaE PF02405.16 EON34733.1 - 1.2e-54 185.2 27.1 1.5e-54 184.9 27.1 1.1 1 0 0 1 1 1 1 Permease MlaE MlaE PF02405.16 EON34734.1 - 1.6e-59 201.2 21.4 1.8e-59 201.0 21.4 1.0 1 0 0 1 1 1 1 Permease MlaE adh_short PF00106.25 EON34735.1 - 1.1e-39 136.0 1.9 1.4e-39 135.6 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON34735.1 - 6.7e-38 130.6 4.4 2e-37 129.0 4.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON34735.1 - 2.3e-15 57.0 2.5 7.6e-15 55.3 2.5 1.7 1 1 0 1 1 1 1 KR domain Fer4_15 PF13459.6 EON34736.1 - 4.6e-09 36.9 1.0 5.1e-09 36.7 1.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 EON34736.1 - 5.7e-09 36.4 0.2 6.8e-09 36.1 0.2 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 EON34736.1 - 7.3e-08 32.4 0.0 8.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Acyl-CoA_dh_1 PF00441.24 EON34737.1 - 3.6e-38 131.1 0.1 5.8e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON34737.1 - 2.9e-21 75.5 0.0 4.8e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON34737.1 - 6.1e-19 68.8 0.0 1.4e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON34737.1 - 0.00013 22.3 0.4 0.0004 20.7 0.4 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EON34737.1 - 0.019 15.5 0.0 0.085 13.4 0.0 1.9 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EON34738.1 - 4.8e-27 95.0 4.1 8e-27 94.3 4.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON34738.1 - 3.7e-11 43.7 0.1 1.2e-10 42.1 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON34738.1 - 8.3e-10 39.1 3.1 8.3e-10 39.1 3.1 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON34738.1 - 0.00078 19.6 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AMP-binding PF00501.28 EON34739.1 - 2.3e-69 234.1 0.0 2.8e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34739.1 - 7.4e-10 39.7 0.2 2.4e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1772 PF08592.11 EON34741.1 - 0.62 10.4 10.1 1 9.7 10.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3488 PF11992.8 EON34741.1 - 1.2 8.1 9.0 1.3 8.0 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) FtsL PF04999.13 EON34742.1 - 0.51 10.4 3.3 0.24 11.4 1.2 1.5 1 1 1 2 2 2 0 Cell division protein FtsL Baculo_11_kDa PF06143.11 EON34742.1 - 4.3 7.0 5.5 16 5.1 0.8 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF1275 PF06912.11 EON34744.1 - 1.5e-23 83.7 23.3 1.8e-23 83.5 23.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sugar_tr PF00083.24 EON34744.1 - 0.0053 15.7 3.2 0.0076 15.2 0.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter COX14 PF14880.6 EON34744.1 - 0.31 10.9 2.6 0.75 9.7 2.6 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly NMO PF03060.15 EON34745.1 - 9.8e-49 166.5 0.2 5.8e-48 164.0 0.2 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EON34745.1 - 2.2e-09 36.8 4.0 3.5e-09 36.1 4.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EON34745.1 - 1.1e-05 24.6 0.0 0.054 12.5 1.3 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EON34745.1 - 0.0097 15.1 6.2 0.067 12.3 0.4 2.1 2 0 0 2 2 2 2 Conserved region in glutamate synthase PEP_hydrolase PF09370.10 EON34745.1 - 0.062 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Phage_TAC_14 PF16462.5 EON34745.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC ThiG PF05690.14 EON34745.1 - 0.34 10.2 3.5 0.44 9.8 2.3 1.6 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG AMP-binding PF00501.28 EON34746.1 - 7.3e-60 202.7 0.0 8.8e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34746.1 - 8.4e-17 61.9 0.3 2.6e-16 60.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 EON34747.1 - 8e-57 192.4 0.0 9.2e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34747.1 - 8.7e-30 104.4 0.0 3.4e-27 95.8 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ANTAR PF03861.14 EON34748.1 - 1.6e-17 63.1 0.9 8.3e-17 60.8 0.2 2.2 2 0 0 2 2 2 1 ANTAR domain PAS_3 PF08447.12 EON34748.1 - 1.3e-12 47.9 0.1 1.2e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EON34748.1 - 0.0016 18.7 0.4 0.0031 17.7 0.4 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EON34748.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold Bac_luciferase PF00296.20 EON34749.1 - 2.2e-69 234.3 8.3 2.8e-69 234.0 8.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase OB_aCoA_assoc PF01796.17 EON34750.1 - 6.7e-25 86.9 6.6 3.6e-12 46.1 0.1 2.8 3 0 0 3 3 3 2 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 EON34750.1 - 0.016 15.1 0.2 0.46 10.4 0.1 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Thiolase_C PF02803.18 EON34751.1 - 0.0072 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 EON34752.1 - 4.1e-05 23.1 0.6 0.00055 19.4 0.4 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Peptidase_M22 PF00814.25 EON34752.1 - 0.018 14.8 0.2 0.027 14.2 0.2 1.2 1 0 0 1 1 1 0 Glycoprotease family ACP_syn_III PF08545.10 EON34752.1 - 0.076 12.9 0.3 17 5.4 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CMD PF02627.20 EON34753.1 - 1.5e-08 34.6 0.4 4.7e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF2157 PF09925.9 EON34754.1 - 0.082 12.7 8.6 0.17 11.7 8.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) YtpI PF14007.6 EON34754.1 - 0.09 12.9 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 YtpI-like protein DUF543 PF04418.12 EON34754.1 - 0.19 11.7 1.0 0.64 10.0 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF4225 PF13988.6 EON34754.1 - 0.52 9.9 0.1 0.52 9.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) DUF3040 PF11239.8 EON34754.1 - 1.6 9.1 18.3 0.48 10.7 3.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Sigma70_r2 PF04542.14 EON34755.1 - 7.7e-16 57.6 3.2 7.7e-16 57.6 3.2 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EON34755.1 - 6.8e-11 41.5 0.1 1.1e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EON34755.1 - 1.1e-06 28.2 0.1 1.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 NPIP PF06409.11 EON34755.1 - 0.097 11.7 0.1 3.8 6.5 0.1 2.0 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) SnoaL_2 PF12680.7 EON34756.1 - 3.4e-09 37.3 0.5 4.9e-09 36.8 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EON34756.1 - 0.0048 17.4 0.0 0.0059 17.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain p450 PF00067.22 EON34757.1 - 3.2e-19 69.0 0.2 1.3e-14 53.8 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 ATG_C PF09333.11 EON34757.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Thiolase_N PF00108.23 EON34758.1 - 1.2e-55 188.7 0.3 2.9e-54 184.1 0.0 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON34758.1 - 2.3e-42 143.5 0.2 1.2e-41 141.2 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 EON34758.1 - 0.0047 17.1 0.3 0.014 15.5 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EON34758.1 - 0.045 13.6 1.0 5.3 7.0 0.3 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III F420H2_quin_red PF04075.14 EON34759.1 - 4.1e-44 149.9 0.1 5e-44 149.6 0.1 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Putative_PNPOx PF01243.20 EON34759.1 - 0.099 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase MDMPI_N PF11716.8 EON34760.1 - 6.7e-10 39.8 10.3 6.7e-10 39.8 10.3 3.1 2 2 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 EON34760.1 - 0.13 12.8 1.0 0.26 11.8 1.0 1.6 1 1 0 1 1 1 0 DinB superfamily WYL PF13280.6 EON34761.1 - 9.3e-30 103.9 1.2 1.2e-29 103.5 1.2 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 EON34761.1 - 1e-15 57.4 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 EON34761.1 - 1.5e-07 31.0 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EON34761.1 - 9.3e-05 22.7 0.1 0.0002 21.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_AsnC-type PF13404.6 EON34761.1 - 0.00011 22.0 0.6 0.00034 20.4 0.6 2.0 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 EON34761.1 - 0.00026 20.7 0.3 0.00026 20.7 0.3 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EON34761.1 - 0.0012 18.9 2.7 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EON34761.1 - 0.0017 17.8 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EON34761.1 - 0.0093 16.0 0.2 0.029 14.4 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 EON34761.1 - 0.017 15.2 0.0 0.052 13.6 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain MarR_2 PF12802.7 EON34761.1 - 0.024 14.5 0.2 0.083 12.8 0.2 1.9 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 EON34761.1 - 0.028 14.4 1.6 0.16 12.0 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Mga PF08280.11 EON34761.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_10 PF04967.12 EON34761.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain MarR PF01047.22 EON34761.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_15 PF12324.8 EON34761.1 - 0.075 13.0 0.3 0.25 11.3 0.3 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Put_DNA-bind_N PF06971.13 EON34761.1 - 0.11 12.6 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Mga PF05043.13 EON34761.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF3540 PF12059.8 EON34762.1 - 0.019 14.8 2.5 0.06 13.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) CsoSCA PF08936.10 EON34762.1 - 0.045 12.4 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase AMP-binding PF00501.28 EON34763.1 - 2.7e-79 266.8 0.0 3.5e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34763.1 - 9.1e-19 68.2 4.1 1.5e-18 67.5 1.7 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EON34763.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Acetyltransf_3 PF13302.7 EON34764.1 - 2.2e-05 25.1 0.0 4.8e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DNA_topoisoIV PF00521.20 EON34764.1 - 4.9e-05 22.4 0.1 6.3e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Acetyltransf_7 PF13508.7 EON34764.1 - 0.00037 20.8 0.0 0.001 19.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EON34764.1 - 0.0019 18.4 0.0 0.0073 16.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EON34764.1 - 0.018 15.0 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SnoaL_2 PF12680.7 EON34765.1 - 2.9e-05 24.7 1.0 3.6e-05 24.3 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.25 EON34766.1 - 1.8e-47 161.4 6.3 2.2e-47 161.1 6.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON34766.1 - 1.6e-43 149.0 10.2 2e-43 148.6 10.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON34766.1 - 2.5e-13 50.3 4.9 5.5e-13 49.2 4.9 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EON34766.1 - 0.13 12.2 1.2 0.29 11.0 1.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 EON34767.1 - 2.8e-53 180.9 2.7 3.3e-53 180.7 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34767.1 - 1.8e-43 148.3 0.3 2.4e-43 147.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34767.1 - 4.6e-12 46.2 2.3 1.2e-11 44.9 2.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EON34767.1 - 0.00074 19.0 0.2 0.0015 18.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ECH_1 PF00378.20 EON34768.1 - 1.5e-38 132.6 0.1 1.7e-38 132.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34768.1 - 1.3e-17 64.3 0.1 2.1e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DLH PF01738.18 EON34768.1 - 0.11 12.0 1.5 8.6 5.8 0.6 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Nuc_deoxyrib_tr PF05014.15 EON34768.1 - 0.69 9.9 3.3 0.97 9.4 0.1 2.5 2 1 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase CoA_trans PF01144.23 EON34769.1 - 1.7e-42 145.3 0.0 2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase CitF PF04223.12 EON34769.1 - 0.26 10.1 0.0 0.41 9.5 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 EON34770.1 - 0.006 16.0 0.0 0.049 13.0 0.0 2.1 1 1 0 1 1 1 1 Coenzyme A transferase NMO PF03060.15 EON34771.1 - 1e-92 311.1 4.8 7.2e-67 226.1 0.8 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EON34771.1 - 1.7e-09 37.2 3.1 4.6e-09 35.7 3.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EON34771.1 - 9.3e-07 28.2 4.4 1.4e-06 27.6 4.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Carmo_coat_C PF08462.10 EON34771.1 - 0.14 12.3 0.5 0.49 10.5 0.2 2.0 2 0 0 2 2 2 0 Carmovirus coat protein ABC_tran PF00005.27 EON34772.1 - 1.6e-28 99.9 0.0 2.1e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34772.1 - 1.8e-08 34.6 5.7 6.9e-05 22.8 0.5 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON34772.1 - 0.002 17.8 0.1 0.0064 16.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EON34772.1 - 0.005 16.4 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EON34772.1 - 0.0083 15.6 0.0 0.78 9.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EON34772.1 - 0.031 14.8 0.1 0.049 14.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EON34772.1 - 0.032 14.0 0.1 0.28 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EON34772.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 EON34772.1 - 0.2 12.0 2.2 1 9.7 2.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EON34773.1 - 1.5e-29 103.2 0.0 3.6e-29 102.0 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 EON34773.1 - 6.5e-13 48.9 5.4 1e-12 48.3 5.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON34773.1 - 1.1e-12 47.9 0.0 4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EON34773.1 - 6.1e-07 29.5 0.1 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EON34773.1 - 6e-05 23.5 0.2 0.00016 22.1 0.1 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 EON34773.1 - 0.0002 21.0 0.2 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EON34773.1 - 0.0011 19.4 0.0 0.02 15.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EON34773.1 - 0.0013 19.1 0.0 0.022 15.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EON34773.1 - 0.0074 16.0 0.3 0.024 14.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EON34773.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EON34773.1 - 0.043 13.1 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 EON34773.1 - 0.047 13.7 0.0 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 EON34773.1 - 0.066 12.0 0.2 0.24 10.2 0.1 1.9 2 1 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EON34773.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF3917 PF13055.6 EON34773.1 - 0.13 12.7 3.3 0.45 11.0 3.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) Cytidylate_kin PF02224.18 EON34773.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_15 PF13175.6 EON34773.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 EON34773.1 - 0.16 12.2 0.2 2.2 8.6 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EON34773.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EON34774.1 - 2.9e-28 99.1 0.0 4.7e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EON34774.1 - 8.4e-22 78.1 1.0 1.2e-21 77.6 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EON34774.1 - 4.1e-06 26.4 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EON34774.1 - 0.00038 20.1 0.1 0.00096 18.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EON34774.1 - 0.001 19.5 2.2 0.0014 19.0 0.4 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EON34774.1 - 0.002 17.9 0.0 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EON34774.1 - 0.0042 17.0 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EON34774.1 - 0.0085 15.7 2.9 0.022 14.4 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 EON34774.1 - 0.0099 16.2 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EON34774.1 - 0.02 13.7 0.1 0.98 8.1 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EON34774.1 - 0.021 14.1 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EON34774.1 - 0.024 15.2 0.0 0.036 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EON34774.1 - 0.024 14.4 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EON34774.1 - 0.026 14.7 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EON34774.1 - 0.049 13.0 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EON34774.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EON34774.1 - 0.17 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TetR_C_24 PF17932.1 EON34775.1 - 1.5e-20 73.5 0.2 2.5e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON34775.1 - 6.4e-17 61.1 0.1 1.4e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 EON34775.1 - 4.9e-06 26.6 0.1 8.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 EON34775.1 - 7.1e-06 26.3 3.6 0.00017 21.9 0.0 2.9 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EON34775.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_17 PF17922.1 EON34775.1 - 0.0072 16.4 0.3 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_5 PF08360.11 EON34775.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.7 2 1 0 2 2 2 0 QacR-like protein, C-terminal region Aldedh PF00171.22 EON34776.1 - 4.8e-74 249.5 0.0 5.7e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3918 PF13056.6 EON34776.1 - 0.06 13.0 0.5 0.06 13.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) LuxC PF05893.14 EON34776.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Thiolase_N PF00108.23 EON34777.1 - 7.7e-54 182.8 1.4 1.1e-53 182.2 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EON34777.1 - 8.6e-44 148.1 0.0 2.2e-43 146.8 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EON34777.1 - 8.1e-05 22.3 2.1 0.00016 21.4 0.8 2.0 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.6 EON34778.1 - 6.6e-54 182.9 5.8 8.3e-54 182.6 5.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34778.1 - 1.6e-46 158.2 0.6 1.6e-46 158.2 0.6 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EON34778.1 - 1.4e-09 38.1 0.4 2.6e-09 37.3 0.4 1.5 1 1 0 1 1 1 1 KR domain Acyl-CoA_dh_M PF02770.19 EON34779.1 - 3.7e-23 81.5 0.0 5.9e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EON34779.1 - 2.3e-22 79.8 0.3 3.9e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EON34779.1 - 1.2e-18 67.8 0.1 2.9e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.28 EON34780.1 - 6.4e-92 308.4 0.0 7.5e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34780.1 - 2.1e-18 67.0 0.0 5.6e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MTES_1575 PF18741.1 EON34781.1 - 1.4e-11 44.4 0.0 3.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 EON34781.1 - 1.5e-11 44.2 0.0 2.4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) AbiEi_4 PF13338.6 EON34781.1 - 1.3e-06 28.4 0.4 1.3e-06 28.4 0.4 1.9 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin AbiEi_3_N PF17194.4 EON34781.1 - 0.024 14.7 0.0 0.073 13.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain tRNA-synt_2 PF00152.20 EON34782.1 - 1.4e-67 228.0 0.0 1.8e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EON34782.1 - 1.8e-09 37.5 0.1 3.3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EON34782.1 - 0.00019 21.0 0.4 0.024 14.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FMN_dh PF01070.18 EON34783.1 - 0.079 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase FAD_binding_3 PF01494.19 EON34784.1 - 1.3e-20 73.9 8.2 4.8e-10 39.2 2.0 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EON34784.1 - 4.8e-07 29.7 11.2 5.7e-06 26.1 4.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EON34784.1 - 9.7e-07 28.3 2.8 4e-05 23.0 1.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34784.1 - 3.3e-06 27.2 3.5 8.1e-06 26.0 3.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EON34784.1 - 7.5e-06 26.4 1.5 2.3e-05 24.9 1.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EON34784.1 - 1.3e-05 24.4 6.0 1.3e-05 24.4 6.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EON34784.1 - 9.5e-05 21.6 7.5 0.00042 19.5 3.4 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EON34784.1 - 0.001 18.4 2.6 0.0024 17.2 2.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EON34784.1 - 0.0016 17.2 2.9 0.0023 16.7 2.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EON34784.1 - 0.0051 16.1 2.0 0.009 15.3 2.0 1.3 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 EON34784.1 - 0.023 14.3 0.7 0.039 13.5 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 EON34784.1 - 0.037 12.9 3.9 0.062 12.1 1.8 2.2 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EON34784.1 - 0.04 14.4 0.1 0.076 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 EON34784.1 - 0.049 13.0 7.4 0.07 12.5 7.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EON34784.1 - 0.051 12.6 3.6 0.071 12.2 3.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EON34784.1 - 0.15 11.4 2.5 0.3 10.3 0.9 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EON34784.1 - 0.18 11.0 0.8 0.31 10.2 0.8 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EON34784.1 - 0.23 11.1 2.2 0.38 10.4 2.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EON34784.1 - 0.27 11.1 3.2 0.43 10.5 3.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TetR_C_31 PF17940.1 EON34785.1 - 4.5e-16 59.0 8.6 4.5e-16 59.0 8.6 1.6 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EON34785.1 - 1.2e-05 25.0 0.1 2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EON34785.1 - 0.048 13.9 4.0 0.26 11.5 4.0 2.2 1 1 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal TetR_C_28 PF17937.1 EON34785.1 - 0.057 13.9 1.5 0.088 13.3 1.5 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_6 PF12697.7 EON34786.1 - 2.8e-22 80.4 16.7 4.5e-22 79.7 16.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EON34786.1 - 1.6e-16 60.3 0.0 2.3e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EON34786.1 - 2.5e-11 43.7 0.0 4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EON34786.1 - 3.7e-05 24.0 0.0 9.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.21 EON34786.1 - 8e-05 22.2 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EON34786.1 - 0.0021 17.6 0.0 0.016 14.8 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EON34786.1 - 0.0081 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 EON34786.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) TetR_N PF00440.23 EON34787.1 - 3.5e-13 49.1 0.4 9.7e-13 47.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_11 PF08279.12 EON34787.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain Pan_kinase PF03309.14 EON34788.1 - 4e-58 196.7 0.0 4.7e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Type III pantothenate kinase Asp_decarbox PF02261.16 EON34789.1 - 6.2e-52 174.4 0.2 7.2e-52 174.2 0.2 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase CDC48_N PF02359.18 EON34789.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Pantoate_ligase PF02569.15 EON34790.1 - 2e-94 315.8 0.0 2.3e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Rossmann-like PF10727.9 EON34791.1 - 7.2e-46 155.2 6.4 7.2e-46 155.2 6.4 1.9 2 1 0 2 2 2 1 Rossmann-like domain DUF2520 PF10728.9 EON34791.1 - 3.9e-36 123.6 0.8 5.9e-36 123.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) F420_oxidored PF03807.17 EON34791.1 - 9.7e-07 29.3 1.0 1.7e-06 28.5 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EON34791.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EON34791.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 EON34791.1 - 0.034 14.1 2.1 1 9.3 1.9 2.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pkinase PF00069.25 EON34792.1 - 3.8e-40 137.9 0.0 4.8e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EON34792.1 - 8e-23 81.0 0.0 1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EON34792.1 - 0.0011 18.9 2.9 0.066 13.1 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EON34792.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EON34792.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TraL PF07178.11 EON34793.1 - 8.6 6.9 9.6 0.11 13.0 1.2 2.2 3 0 0 3 3 3 0 TraL protein SLATT_1 PF18181.1 EON34794.1 - 0.0084 16.0 2.3 0.015 15.2 2.3 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 1 DUF4131 PF13567.6 EON34794.1 - 0.02 14.5 0.5 0.03 14.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) gerPA PF10676.9 EON34794.1 - 0.14 12.4 1.0 0.32 11.2 1.0 1.6 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF S_4TM PF18159.1 EON34794.1 - 9.5 5.4 6.2 4.5 6.5 4.0 1.5 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3180 PF11377.8 EON34795.1 - 2.3e-42 144.4 17.3 2.6e-42 144.2 17.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) DUF983 PF06170.12 EON34795.1 - 0.046 14.1 3.2 0.65 10.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF983) Ytca PF17090.5 EON34795.1 - 0.94 10.0 4.3 0.42 11.2 1.3 2.0 2 1 0 2 2 2 0 Uncharacterised protein family DUF308 PF03729.13 EON34795.1 - 0.98 9.8 14.2 18 5.7 0.0 3.0 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4383 PF14325.6 EON34795.1 - 5.7 7.2 11.9 7.2 6.9 8.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) HPPK PF01288.20 EON34796.1 - 1.6e-29 102.7 0.0 1.9e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EON34797.1 - 4.3e-32 111.0 0.0 4.8e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Pterin_bind PF00809.22 EON34798.1 - 3.9e-82 275.6 0.1 4.7e-82 275.3 0.1 1.1 1 0 0 1 1 1 1 Pterin binding enzyme GTP_cyclohydroI PF01227.22 EON34799.1 - 4.1e-75 251.1 0.0 4.6e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I Peptidase_M41 PF01434.18 EON34800.1 - 8.6e-72 241.0 0.5 1.4e-71 240.3 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EON34800.1 - 3.6e-45 153.6 0.0 7.8e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EON34800.1 - 3.4e-14 52.4 0.4 6.9e-14 51.4 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EON34800.1 - 2.2e-05 24.5 0.0 9.3e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EON34800.1 - 0.0002 21.8 0.8 0.006 17.0 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EON34800.1 - 0.00026 20.3 0.1 0.00057 19.2 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EON34800.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EON34800.1 - 0.0026 18.0 0.1 0.055 13.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EON34800.1 - 0.0041 17.3 0.0 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EON34800.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EON34800.1 - 0.034 13.5 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EON34800.1 - 0.066 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsH_ext PF06480.15 EON34800.1 - 0.067 13.6 3.1 0.96 9.8 0.1 2.4 1 1 1 2 2 2 0 FtsH Extracellular TsaE PF02367.17 EON34800.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EON34800.1 - 0.11 13.1 0.0 0.36 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EON34800.1 - 0.16 12.1 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Pribosyltran PF00156.27 EON34801.1 - 6.1e-21 74.6 0.0 7.5e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Phage_holin_8 PF16931.5 EON34801.1 - 0.094 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative phage holin THF_DHG_CYH_C PF02882.19 EON34801.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UPRTase PF14681.6 EON34801.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Gly-zipper_Omp PF13488.6 EON34802.1 - 0.0051 16.8 9.1 0.0051 16.8 9.1 2.6 1 1 1 2 2 2 1 Glycine zipper ATP_bind_3 PF01171.20 EON34803.1 - 1.6e-32 112.7 0.0 2.3e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 PP-loop family TilS PF09179.11 EON34803.1 - 7.3e-05 23.2 0.3 0.00033 21.1 0.2 2.2 2 0 0 2 2 2 1 TilS substrate binding domain NAD_synthase PF02540.17 EON34803.1 - 0.14 11.3 0.3 5 6.2 0.1 2.3 2 0 0 2 2 2 0 NAD synthase QueC PF06508.13 EON34803.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Amidohydro_2 PF04909.14 EON34803.1 - 0.15 11.8 3.5 0.21 11.3 2.9 1.6 1 1 0 1 1 1 0 Amidohydrolase Zincin_2 PF10103.9 EON34804.1 - 1.5e-105 353.1 0.7 1.8e-105 352.9 0.7 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_S13 PF02113.15 EON34805.1 - 4.9e-78 262.8 1.8 3.5e-49 167.7 0.1 2.0 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.20 EON34805.1 - 0.0025 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Pyrophosphatase PF00719.19 EON34806.1 - 1.5e-51 174.4 0.0 1.7e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 EON34806.1 - 0.00036 20.3 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Inorganic Pyrophosphatase Aldedh PF00171.22 EON34807.1 - 2e-165 550.8 0.0 2.2e-165 550.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EON34807.1 - 0.039 13.4 0.0 7.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GNAT_like PF18407.1 EON34807.1 - 6.2 7.2 7.8 0.62 10.5 1.4 2.8 3 0 0 3 3 3 0 GCN5-related N-acetyltransferase like domain ADH_N PF08240.12 EON34808.1 - 2e-26 92.0 0.4 3.8e-26 91.1 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EON34808.1 - 4.1e-19 68.8 0.6 8.3e-19 67.8 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EON34808.1 - 3.1e-05 23.6 0.7 5.2e-05 22.8 0.7 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EON34808.1 - 0.00014 22.9 0.0 0.00047 21.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF711 PF05167.12 EON34808.1 - 0.048 12.6 0.5 0.065 12.1 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) AlaDh_PNT_C PF01262.21 EON34808.1 - 0.082 12.2 5.2 0.13 11.5 5.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BPD_transp_2 PF02653.16 EON34809.1 - 6.2e-33 114.1 47.9 8.1e-33 113.7 47.9 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Oxidored_q6 PF01058.22 EON34809.1 - 0.26 11.1 1.5 0.38 10.6 0.4 1.7 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit ABC_tran PF00005.27 EON34810.1 - 1.5e-37 129.2 0.0 4.8e-25 88.7 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EON34810.1 - 3.1e-13 50.2 0.1 0.00014 21.7 0.0 3.1 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EON34810.1 - 0.0029 17.3 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EON34810.1 - 0.0049 16.3 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EON34810.1 - 0.022 14.5 1.7 0.04 13.6 0.8 2.1 2 1 1 3 3 3 0 AAA domain MeaB PF03308.16 EON34810.1 - 0.031 13.3 0.1 0.057 12.4 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EON34810.1 - 0.039 14.5 0.0 0.058 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 EON34810.1 - 0.043 13.1 0.0 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_15 PF13175.6 EON34810.1 - 0.051 13.3 0.1 0.075 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EON34810.1 - 0.054 13.4 0.1 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EON34810.1 - 0.098 13.0 0.6 0.28 11.5 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_4 PF08386.10 EON34810.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Zeta_toxin PF06414.12 EON34810.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EON34810.1 - 0.16 12.1 0.1 0.48 10.5 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 EON34810.1 - 0.16 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EON34810.1 - 0.85 9.2 5.8 15 5.1 0.1 3.4 3 1 0 3 3 3 0 AAA domain BPD_transp_2 PF02653.16 EON34811.1 - 7.2e-38 130.3 44.9 7e-37 127.0 45.7 1.8 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component EpCAM_N PF18635.1 EON34811.1 - 0.17 12.1 0.7 0.33 11.1 0.7 1.4 1 0 0 1 1 1 0 Epithelial cell adhesion molecule N-terminal domain CPP1-like PF11833.8 EON34811.1 - 0.61 9.7 12.5 0.24 11.1 8.7 2.1 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Peripla_BP_4 PF13407.6 EON34812.1 - 1.3e-29 103.6 8.5 1.8e-29 103.1 8.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 EON34812.1 - 8.7e-06 26.2 0.0 3.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EON34812.1 - 6.8e-05 22.4 0.1 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Acyl-CoA_dh_1 PF00441.24 EON34813.1 - 7e-42 143.2 2.3 1e-41 142.7 2.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EON34813.1 - 2.5e-25 88.5 0.0 2.2e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EON34813.1 - 3.1e-23 82.6 0.0 7.2e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EON34813.1 - 3e-18 66.4 3.1 4.7e-18 65.8 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EON34813.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal CoA_trans PF01144.23 EON34814.1 - 2e-33 115.7 4.9 1.3e-26 93.4 0.1 2.4 2 1 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EON34814.1 - 1.1e-06 27.3 0.4 2.1e-06 26.4 0.1 1.5 2 0 0 2 2 2 1 Malonate decarboxylase, alpha subunit, transporter Cas_Cas6 PF01881.16 EON34814.1 - 0.067 13.7 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Peripla_BP_3 PF13377.6 EON34815.1 - 9.4e-35 120.4 0.5 7.5e-34 117.4 0.3 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EON34815.1 - 2e-27 96.4 0.0 2.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EON34815.1 - 7e-16 57.8 1.3 1.1e-15 57.1 1.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EON34815.1 - 2.9e-10 40.2 0.0 1.1e-09 38.3 0.0 1.9 2 1 0 2 2 2 1 Periplasmic binding protein domain HTH_3 PF01381.22 EON34815.1 - 0.004 17.2 0.1 0.01 15.9 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EON34815.1 - 0.0058 17.0 0.5 0.018 15.4 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain AP_endonuc_2 PF01261.24 EON34816.1 - 2.8e-33 115.2 0.4 3.5e-33 114.8 0.4 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF993 PF06187.11 EON34817.1 - 1.4e-161 537.7 0.8 1.6e-161 537.5 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF993) adh_short_C2 PF13561.6 EON34818.1 - 1.3e-67 227.8 4.3 1.5e-67 227.6 4.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34818.1 - 2.8e-49 167.2 2.3 3.6e-49 166.9 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EON34818.1 - 1e-08 35.0 1.7 1e-08 35.0 1.7 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EON34818.1 - 4.3e-07 30.0 6.6 1.8e-06 28.0 6.6 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EON34818.1 - 0.00025 20.3 0.6 0.00049 19.3 0.5 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EON34818.1 - 0.00027 20.1 0.8 0.00039 19.6 0.8 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EON34818.1 - 0.0025 17.2 1.5 0.0048 16.4 1.5 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EON34818.1 - 0.0062 16.4 3.4 0.0091 15.9 3.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EON34818.1 - 0.013 15.8 0.5 0.028 14.7 0.5 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EON34818.1 - 0.023 14.1 0.5 0.048 13.0 0.5 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EON34818.1 - 0.065 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.19 EON34818.1 - 0.075 12.0 1.1 0.1 11.6 1.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EON34818.1 - 0.12 12.2 1.7 0.56 10.1 2.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EON34818.1 - 0.34 10.4 3.5 0.42 10.1 2.3 1.7 2 0 0 2 2 2 0 NmrA-like family Gly_kinase PF02595.15 EON34819.1 - 3.9e-94 315.7 8.3 4.6e-94 315.4 8.3 1.0 1 0 0 1 1 1 1 Glycerate kinase family DUF5444 PF17519.2 EON34819.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5444) MaoC_dehydratas PF01575.19 EON34820.1 - 1e-17 63.9 0.0 1.2e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 EON34820.1 - 0.00074 19.8 0.1 0.0014 18.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydrat_N PF13452.6 EON34820.1 - 0.0074 16.4 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT_2 PF13279.6 EON34820.1 - 0.12 12.9 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily CoA_trans PF01144.23 EON34821.1 - 8e-35 120.2 0.2 4.4e-32 111.2 0.1 2.4 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EON34821.1 - 2.3e-05 22.9 0.1 3.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter CASP_C PF08172.12 EON34822.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 CASP C terminal Aminotran_5 PF00266.19 EON34823.1 - 8.6e-78 261.9 0.0 1e-77 261.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EON34823.1 - 1.2e-08 34.6 0.0 5.9e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EON34823.1 - 0.00011 21.6 0.1 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 EON34823.1 - 0.097 11.6 0.0 0.2 10.6 0.0 1.4 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Chorismate_bind PF00425.18 EON34824.1 - 3.1e-68 230.1 0.0 3.9e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Cys_Met_Meta_PP PF01053.20 EON34825.1 - 6.7e-131 436.3 0.0 7.5e-131 436.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EON34825.1 - 5.8e-05 22.4 0.0 8.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EON34825.1 - 0.00013 21.0 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EON34825.1 - 0.00078 18.8 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.13 EON34825.1 - 0.0042 16.1 1.2 0.32 9.9 1.2 2.1 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.21 EON34825.1 - 0.084 12.1 0.4 0.57 9.4 0.4 2.2 1 1 0 1 1 1 0 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EON34825.1 - 0.2 10.1 0.0 1.6 7.1 0.0 1.9 2 0 0 2 2 2 0 Methionine gamma-lyase Rhodanese PF00581.20 EON34826.1 - 3.2e-07 30.8 0.0 5.9e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain ATP-synt_J PF04911.12 EON34827.1 - 0.013 15.1 1.4 0.031 13.9 1.4 1.6 1 0 0 1 1 1 0 ATP synthase j chain DUF4878 PF12870.7 EON34827.1 - 0.016 15.5 0.1 0.02 15.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) SnoaL_2 PF12680.7 EON34827.1 - 0.016 15.8 0.7 0.029 15.0 0.7 1.5 1 1 0 1 1 1 0 SnoaL-like domain Peripla_BP_2 PF01497.18 EON34828.1 - 6.2e-16 58.7 0.0 8.8e-16 58.2 0.0 1.3 1 1 0 1 1 1 1 Periplasmic binding protein Pyr_redox_2 PF07992.14 EON34829.1 - 4.2e-11 42.6 0.0 8.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EON34829.1 - 1.4e-05 25.6 0.6 0.28 11.8 0.1 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EON34829.1 - 4.6e-05 23.5 0.1 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EON34829.1 - 0.00013 21.4 0.4 0.4 9.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EON34829.1 - 0.00031 20.9 0.0 0.00092 19.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EON34829.1 - 0.02 13.6 0.1 0.031 13.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EON34829.1 - 0.048 12.9 0.2 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EON34829.1 - 0.12 11.7 0.0 0.49 9.7 0.0 2.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EON34829.1 - 0.12 11.6 0.0 9.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EON34829.1 - 0.12 11.5 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EON34829.1 - 0.16 12.4 0.0 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 EON34829.1 - 0.23 9.8 0.0 0.46 8.8 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FecCD PF01032.18 EON34831.1 - 8.4e-83 277.9 31.1 1.5e-82 277.1 31.1 1.3 1 1 0 1 1 1 1 FecCD transport family FecCD PF01032.18 EON34832.1 - 8.6e-73 245.1 39.3 1.1e-72 244.6 39.3 1.1 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EON34832.1 - 2.4 7.6 27.7 0.046 13.2 17.7 2.4 1 1 1 2 2 2 0 ABC 3 transport family ABC_tran PF00005.27 EON34833.1 - 2.3e-29 102.7 0.0 3.1e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EON34833.1 - 2.5e-08 34.1 0.5 5.4e-05 23.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EON34833.1 - 7.1e-08 32.2 0.0 0.0053 16.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EON34833.1 - 6.3e-06 26.1 0.0 6e-05 22.9 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EON34833.1 - 1.1e-05 25.9 0.6 3.8e-05 24.1 0.6 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EON34833.1 - 4.2e-05 23.2 0.0 8.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EON34833.1 - 6.6e-05 23.5 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EON34833.1 - 9.2e-05 21.4 1.1 0.01 14.7 0.1 2.8 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 EON34833.1 - 0.00017 21.9 0.2 0.0008 19.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EON34833.1 - 0.00031 20.2 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EON34833.1 - 0.00054 20.0 0.0 0.017 15.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EON34833.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EON34833.1 - 0.0048 17.1 0.0 0.0069 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON34833.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EON34833.1 - 0.0087 15.8 1.1 0.08 12.6 1.1 2.1 1 1 0 1 1 1 1 AAA domain MukB PF04310.12 EON34833.1 - 0.019 14.7 0.1 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 MukB N-terminal AAA_25 PF13481.6 EON34833.1 - 0.023 14.2 2.5 0.29 10.7 2.5 2.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EON34833.1 - 0.028 14.3 0.4 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EON34833.1 - 0.064 13.5 0.5 0.13 12.4 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EON34833.1 - 0.081 12.9 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EON34833.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_27 PF13514.6 EON34833.1 - 0.098 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EON34833.1 - 0.1 12.2 0.4 0.33 10.6 0.1 1.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 EON34833.1 - 0.11 12.2 0.0 7.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 EON34833.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EON34833.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2813 PF11398.8 EON34833.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Voltage_CLC PF00654.20 EON34834.1 - 1.8e-78 264.3 46.2 3.6e-77 260.0 39.6 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel HTH_AsnC-type PF13404.6 EON34835.1 - 3.1e-23 81.3 10.6 2.1e-13 49.8 0.2 3.2 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EON34835.1 - 6.1e-18 64.1 0.4 9.3e-08 31.5 0.0 2.7 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 EON34835.1 - 1.2e-14 54.0 0.0 3.7e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain HTH_20 PF12840.7 EON34835.1 - 2.5e-07 30.6 0.7 0.024 14.7 0.1 3.0 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EON34835.1 - 2.2e-05 24.4 1.5 0.26 11.3 0.0 2.8 3 0 0 3 3 3 2 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EON34835.1 - 0.001 18.9 8.8 0.14 12.0 0.3 3.6 4 0 0 4 4 4 2 MarR family HTH_IclR PF09339.10 EON34835.1 - 0.0029 17.4 1.5 0.11 12.3 0.1 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 EON34835.1 - 0.0072 15.8 2.0 0.47 10.0 0.2 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 EON34835.1 - 0.0098 15.7 4.6 1.3 8.9 0.8 2.6 2 0 0 2 2 2 2 Homeodomain-like domain TrmB PF01978.19 EON34835.1 - 0.011 15.6 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EON34835.1 - 0.02 14.9 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.6 EON34835.1 - 0.036 13.5 0.5 0.51 9.8 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 EAP30 PF04157.16 EON34835.1 - 0.043 13.1 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Sigma70_r4_2 PF08281.12 EON34835.1 - 0.055 13.1 0.0 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Peptidase_A6 PF01829.16 EON34835.1 - 0.062 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase A6 family MarR PF01047.22 EON34835.1 - 0.17 11.9 0.0 4.9 7.2 0.0 2.5 3 0 0 3 3 3 0 MarR family HTH_28 PF13518.6 EON34835.1 - 0.19 11.9 4.5 1.5 9.0 0.7 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.16 EON34836.1 - 1.7e-45 155.5 54.6 1.7e-45 155.5 54.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON34836.1 - 5.2e-07 28.9 4.5 5.2e-07 28.9 4.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EON34836.1 - 0.00017 20.1 16.3 0.00017 20.1 16.3 2.9 1 1 1 3 3 3 1 Transmembrane secretion effector PMT_4TMC PF16192.5 EON34836.1 - 4 7.0 5.7 5.1 6.6 2.6 2.6 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase HTH_IclR PF09339.10 EON34837.1 - 4.8e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain PuR_N PF09182.10 EON34837.1 - 0.0035 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial purine repressor, N-terminal TrmB PF01978.19 EON34837.1 - 0.0096 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EON34837.1 - 0.0097 15.8 0.3 0.046 13.6 0.0 2.3 2 1 0 2 2 2 1 MarR family TetR_N PF00440.23 EON34837.1 - 0.011 15.5 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 EON34837.1 - 0.017 15.0 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR PF01047.22 EON34837.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 EON34837.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 EON34837.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 EON34837.1 - 0.096 12.5 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain TPP_enzyme_N PF02776.18 EON34838.1 - 2.3e-53 180.3 6.0 7.6e-53 178.6 0.3 3.1 3 1 1 4 4 4 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EON34838.1 - 1.5e-32 112.5 0.1 4.4e-32 111.0 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EON34838.1 - 4.3e-32 110.7 0.3 1.3e-31 109.2 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.6 EON34839.1 - 4.6e-65 219.4 2.1 5.8e-65 219.1 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34839.1 - 1.2e-46 158.7 2.1 1.5e-46 158.3 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34839.1 - 1.4e-08 34.9 1.5 2e-08 34.3 1.5 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EON34839.1 - 4.8e-06 26.9 1.0 7.3e-06 26.3 1.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EON34839.1 - 0.00087 18.8 1.6 0.00089 18.8 0.6 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 EON34839.1 - 0.0024 17.9 2.3 0.0042 17.2 2.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EON34839.1 - 0.0027 17.0 8.2 0.016 14.5 4.4 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EON34839.1 - 0.0053 16.1 0.4 0.0071 15.7 0.4 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EON34839.1 - 0.0083 15.5 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 EON34839.1 - 0.025 14.8 0.6 0.054 13.8 0.6 1.6 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EON34839.1 - 0.026 14.6 0.3 0.04 14.0 0.3 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EON34839.1 - 0.032 14.1 2.4 0.047 13.6 2.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EON34839.1 - 0.033 14.1 2.9 0.08 12.9 2.9 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 EON34839.1 - 0.18 12.2 1.1 0.48 10.9 1.2 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AMP-binding PF00501.28 EON34840.1 - 1.3e-98 330.4 0.0 1.7e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34840.1 - 1.2e-21 77.5 1.9 1.2e-21 77.5 1.9 2.2 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Bac_luciferase PF00296.20 EON34842.1 - 2.4e-27 96.2 6.1 5.8e-27 94.9 6.0 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase FA_desaturase PF00487.24 EON34843.1 - 2e-31 109.8 3.3 2.8e-31 109.3 3.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase FAD_binding_6 PF00970.24 EON34844.1 - 3.3e-11 43.4 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 EON34844.1 - 2.7e-09 36.8 0.4 5.2e-09 35.9 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EON34844.1 - 3.3e-07 30.9 0.0 6.9e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EON34844.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF456 PF04306.13 EON34845.1 - 1.9e-26 93.0 28.4 1.9e-26 93.0 28.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF456) CtnDOT_TraJ PF07863.11 EON34845.1 - 0.14 12.9 3.7 0.44 11.2 3.7 1.9 1 1 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon ATP-grasp PF02222.22 EON34846.1 - 9.3e-50 168.5 0.0 1.5e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EON34846.1 - 4e-07 29.8 0.0 6.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Epimerase PF01370.21 EON34846.1 - 1.4e-05 24.7 0.2 2.1e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dala_Dala_lig_C PF07478.13 EON34846.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus PurK_C PF17769.1 EON34846.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain RmlD_sub_bind PF04321.17 EON34846.1 - 0.0022 17.1 0.9 0.0042 16.2 0.7 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EON34846.1 - 0.0048 16.3 0.1 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 EON34846.1 - 0.016 15.2 0.0 0.073 13.1 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 EON34846.1 - 0.023 14.3 0.0 0.12 12.0 0.0 2.1 3 0 0 3 3 3 0 ATP-grasp domain ATP-grasp_5 PF13549.6 EON34846.1 - 0.031 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain 3HCDH_N PF02737.18 EON34846.1 - 0.064 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-UBP PF02148.19 EON34847.1 - 4.8e-10 39.6 9.5 6.4e-10 39.2 9.5 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Na_H_Exchanger PF00999.21 EON34848.1 - 6.2e-57 193.1 31.9 7.5e-57 192.8 31.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2712 PF10916.8 EON34849.1 - 0.047 14.4 0.1 0.07 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) DUF3693 PF12472.8 EON34849.1 - 0.081 12.6 3.7 0.09 12.4 2.6 1.6 2 0 0 2 2 2 0 Phage related protein Tic110 PF16940.5 EON34849.1 - 6.9 5.0 5.6 7.4 4.9 5.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Guanylate_cyc PF00211.20 EON34850.1 - 2.5e-21 76.1 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 EON34850.1 - 1.9e-08 34.6 0.2 4.5e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 HAMP domain Adenylsucc_synt PF00709.21 EON34851.1 - 1.2e-172 574.6 0.0 1.4e-172 574.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Sugar_tr PF00083.24 EON34853.1 - 2.2e-26 92.8 29.8 1.2e-24 87.1 7.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON34853.1 - 1.8e-25 89.6 58.1 2.4e-16 59.6 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EON34853.1 - 5.6e-06 25.2 24.4 5.6e-06 25.2 24.4 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein PRP4 PF08799.11 EON34853.1 - 0.2 11.3 1.0 0.35 10.5 1.0 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Cation_efflux PF01545.21 EON34854.1 - 4.8e-41 140.7 19.0 5.7e-41 140.4 19.0 1.1 1 0 0 1 1 1 1 Cation efflux family BIV_Env PF05858.12 EON34854.1 - 0.67 8.1 4.0 0.93 7.6 4.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF2053 PF09767.9 EON34854.1 - 0.72 10.0 2.9 1.1 9.4 1.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2053) PorA PF11271.8 EON34854.1 - 6.5 5.9 6.8 0.49 9.6 1.0 2.2 2 0 0 2 2 2 0 Porin PorA FUSC_2 PF13515.6 EON34855.1 - 1.9e-16 60.3 10.2 2.9e-16 59.8 10.2 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 EON34855.1 - 5.4e-05 23.4 2.0 8.8e-05 22.7 2.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 Gly-zipper_YMGG PF13441.6 EON34855.1 - 0.29 10.9 11.0 0.11 12.3 2.2 2.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EON34855.1 - 2.2 8.4 9.9 0.28 11.2 2.4 2.5 2 0 0 2 2 2 0 Glycine zipper YtxH PF12732.7 EON34855.1 - 7.5 7.2 7.8 0.36 11.4 0.6 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF3151 PF11349.8 EON34856.1 - 1.9e-55 186.4 1.8 2.3e-55 186.1 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3151) DUF4878 PF12870.7 EON34857.1 - 0.00033 20.9 0.0 0.0014 18.9 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) DUF4330 PF14221.6 EON34857.1 - 0.43 10.8 4.0 0.49 10.6 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4330) PLDc_N PF13396.6 EON34859.1 - 0.0053 16.7 1.7 0.0074 16.2 1.7 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal F_bP_aldolase PF01116.20 EON34860.1 - 1e-81 274.5 0.0 1.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SNARE_assoc PF09335.11 EON34861.1 - 9.6e-22 77.7 3.6 9.6e-22 77.7 3.6 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3084 PF11283.8 EON34861.1 - 0.021 14.8 0.0 0.061 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) SpoU_methylase PF00588.19 EON34862.1 - 5.6e-25 88.2 0.0 7.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Pribosyltran PF00156.27 EON34863.1 - 1.3e-09 37.8 0.9 1.9e-09 37.2 0.9 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.19 EON34865.1 - 2.8e-45 153.9 0.5 4.8e-45 153.1 0.5 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EON34865.1 - 6.7e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EON34865.1 - 0.00031 20.9 0.3 0.00052 20.2 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EON34865.1 - 0.033 14.2 0.1 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EON34865.1 - 0.058 12.7 0.7 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 ThiF family adh_short PF00106.25 EON34865.1 - 0.073 12.5 0.5 0.16 11.4 0.5 1.7 1 0 0 1 1 1 0 short chain dehydrogenase DUF1611_N PF17396.2 EON34865.1 - 0.15 12.4 1.3 2.8 8.2 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Peptidase_S15 PF02129.18 EON34866.1 - 1e-56 192.5 4.2 1.4e-56 192.0 4.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EON34866.1 - 6.5e-56 189.8 0.0 1.2e-55 188.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 EON34866.1 - 0.00055 19.5 0.6 0.0014 18.2 0.5 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family TetR_N PF00440.23 EON34867.1 - 5.8e-06 26.0 0.0 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 EON34867.1 - 2.2e-05 24.4 0.1 4.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 EON34867.1 - 0.00043 20.5 0.6 0.00089 19.5 0.4 1.7 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 EON34867.1 - 0.0056 16.7 0.2 0.02 14.9 0.3 2.0 1 1 1 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_6 PF13977.6 EON34867.1 - 0.006 16.8 2.3 0.006 16.8 2.3 2.1 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal HTH_11 PF08279.12 EON34867.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_7 PF02796.15 EON34867.1 - 0.023 14.8 0.1 7 6.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase TetR_C_5 PF08360.11 EON34867.1 - 0.045 13.9 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 QacR-like protein, C-terminal region UPF0181 PF03701.14 EON34867.1 - 0.065 12.9 1.6 0.28 10.8 0.0 2.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0181) TetR_C_9 PF14514.6 EON34867.1 - 0.069 13.3 0.1 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 EON34868.1 - 4.4e-71 239.7 1.1 5.7e-71 239.3 1.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EON34868.1 - 2.3e-24 86.1 0.8 5.4e-24 85.0 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 EON34869.1 - 1.2e-46 159.1 0.0 1.4e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EON34869.1 - 7.6e-32 111.1 0.0 8.7e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short_C2 PF13561.6 EON34870.1 - 2.1e-63 214.0 6.8 2.4e-63 213.8 6.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34870.1 - 3.4e-52 176.7 2.4 4.1e-52 176.5 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34870.1 - 1.3e-18 67.5 2.1 1.7e-18 67.2 2.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EON34870.1 - 0.0019 17.7 0.3 0.0026 17.3 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EON34870.1 - 0.013 15.4 1.3 0.018 14.9 1.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GRDA PF04723.14 EON34870.1 - 0.07 12.9 2.5 0.55 10.0 0.7 2.9 2 1 1 3 3 3 0 Glycine reductase complex selenoprotein A RmlD_sub_bind PF04321.17 EON34870.1 - 0.08 12.0 1.1 0.14 11.2 1.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 EON34870.1 - 0.14 12.7 2.9 0.17 12.5 1.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 EON34870.1 - 0.4 10.0 5.6 1 8.7 1.5 2.4 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HTH_AsnC-type PF13404.6 EON34871.1 - 6.1e-25 86.8 7.2 1.8e-11 43.7 0.0 3.2 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 EON34871.1 - 6.1e-17 61.4 0.3 3.7e-09 36.4 0.2 2.3 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EON34871.1 - 2e-15 56.0 0.0 2.1e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 EON34871.1 - 5.4e-06 26.1 2.0 3.2e-05 23.7 2.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON34871.1 - 1.3e-05 25.0 3.2 0.0035 17.2 1.2 2.6 2 0 0 2 2 2 2 MarR family HTH_20 PF12840.7 EON34871.1 - 0.0014 18.7 0.4 0.12 12.5 0.9 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EON34871.1 - 0.0027 17.4 2.7 2.1 8.2 0.1 3.2 3 0 0 3 3 3 2 Homeodomain-like domain HTH_5 PF01022.20 EON34871.1 - 0.009 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 EON34871.1 - 0.079 12.9 0.1 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 MarR family HTH_Crp_2 PF13545.6 EON34871.1 - 0.086 12.8 0.3 0.55 10.2 0.2 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TrmB PF01978.19 EON34871.1 - 0.11 12.4 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.12 EON34871.1 - 0.11 12.2 1.0 2 8.2 0.1 2.8 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain GntR PF00392.21 EON34871.1 - 0.23 11.1 2.4 0.23 11.2 0.4 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 EON34871.1 - 2 8.6 5.4 1.1 9.4 0.3 3.0 4 0 0 4 4 4 0 Helix-turn-helix domain Octopine_DH PF02317.17 EON34872.1 - 1.1e-29 103.5 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 EON34872.1 - 1.3e-06 28.4 0.1 0.013 15.4 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EON34872.1 - 5.5e-05 23.7 0.1 0.00025 21.5 0.1 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EON34872.1 - 0.0012 19.0 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 EON34872.1 - 0.003 16.9 0.7 0.0039 16.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EON34872.1 - 0.0081 15.8 0.0 0.022 14.4 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DpaA_N PF16924.5 EON34872.1 - 0.0081 16.2 0.0 0.13 12.4 0.0 2.2 1 1 0 1 1 1 1 Dipicolinate synthase subunit A N-terminal domain Rossmann-like PF10727.9 EON34872.1 - 0.011 15.6 0.8 0.37 10.7 0.2 2.5 2 0 0 2 2 2 0 Rossmann-like domain NAD_binding_8 PF13450.6 EON34872.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EON34872.1 - 0.03 13.6 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 EON34872.1 - 0.05 13.2 0.0 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EON34873.1 - 2e-43 148.4 0.1 2.8e-43 147.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EON34873.1 - 3.1e-17 63.0 0.1 5.9e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EON34873.1 - 0.00085 19.5 2.7 0.0096 16.1 2.7 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 EON34873.1 - 0.0016 18.1 1.1 0.0025 17.4 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EON34873.1 - 0.011 16.0 0.8 0.019 15.2 0.8 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EON34873.1 - 0.052 13.6 0.3 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EON34873.1 - 0.098 12.8 2.1 0.14 12.2 0.5 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EON34873.1 - 0.1 12.0 0.6 0.15 11.4 0.6 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EON34873.1 - 0.12 12.3 0.5 0.31 11.0 0.5 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 EON34873.1 - 0.19 12.2 0.6 0.38 11.2 0.6 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.24 EON34874.1 - 1.1e-23 83.8 29.0 2.9e-18 66.0 7.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EON34874.1 - 4.2e-23 81.8 52.2 6e-13 48.4 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EON34874.1 - 0.2 10.0 6.5 0.32 9.4 3.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DJ-1_PfpI PF01965.24 EON34875.1 - 1.8e-25 89.6 0.0 2.1e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EON34875.1 - 0.038 13.6 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MarR_2 PF12802.7 EON34876.1 - 8.8e-15 54.4 1.0 2.4e-14 52.9 1.0 1.8 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 EON34876.1 - 1.6e-05 24.9 0.2 5e-05 23.3 0.1 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 EON34876.1 - 0.0096 15.9 0.1 0.019 14.9 0.1 1.7 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 EON34876.1 - 0.015 15.1 0.0 0.057 13.2 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain RP-C PF03428.13 EON34876.1 - 0.018 14.7 0.4 0.054 13.2 0.1 1.8 2 0 0 2 2 2 0 Replication protein C N-terminal domain Sigma70_r4 PF04545.16 EON34876.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 EON34876.1 - 0.028 14.5 0.2 0.075 13.2 0.1 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain GP3_package PF16677.5 EON34876.1 - 0.033 14.3 0.0 0.14 12.3 0.0 1.9 1 1 1 2 2 2 0 DNA-packaging protein gp3 GntR PF00392.21 EON34876.1 - 0.038 13.6 0.5 0.1 12.3 0.0 1.9 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 EON34876.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_20 PF12840.7 EON34876.1 - 0.066 13.3 1.4 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 EON34876.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Aminotran_3 PF00202.21 EON34877.1 - 2.6e-113 378.8 0.0 3.1e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FAD-oxidase_C PF02913.19 EON34878.1 - 4e-41 141.3 0.0 6.7e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EON34878.1 - 3.5e-34 117.5 4.7 3.6e-34 117.5 2.7 2.2 2 0 0 2 2 2 1 FAD binding domain Fer4_8 PF13183.6 EON34878.1 - 6.7e-11 42.5 2.4 1.4e-10 41.5 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EON34878.1 - 1.1e-08 35.5 1.1 2.3e-08 34.5 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain CCG PF02754.16 EON34878.1 - 3.6e-07 30.3 0.3 0.015 15.5 0.0 2.5 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_7 PF12838.7 EON34878.1 - 0.00015 22.2 3.4 0.00037 21.0 3.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EON34878.1 - 0.0027 17.8 1.5 0.16 12.1 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 EON34878.1 - 0.067 13.0 1.7 0.18 11.7 1.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_9 PF13187.6 EON34878.1 - 0.072 13.3 2.8 0.17 12.1 2.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 EON34878.1 - 0.1 12.7 1.9 0.29 11.3 1.9 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_18 PF13746.6 EON34878.1 - 0.11 12.7 0.4 0.23 11.7 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EON34878.1 - 0.23 11.6 3.0 0.8 9.9 3.0 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_22 PF17179.4 EON34878.1 - 1.4 9.9 5.3 3.2 8.7 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Aldedh PF00171.22 EON34879.1 - 1.1e-159 531.9 0.1 1.3e-159 531.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3102 PF11300.8 EON34879.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) DUF1487 PF07368.11 EON34879.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Peptidase_M24 PF00557.24 EON34880.1 - 2.4e-26 92.7 0.0 3.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EON34880.1 - 1.2e-21 77.7 0.0 2.5e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Creatinase_N_2 PF16189.5 EON34880.1 - 0.15 12.2 0.0 0.6 10.2 0.0 1.8 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Aminotran_1_2 PF00155.21 EON34881.1 - 1.5e-30 106.7 0.0 1.6e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EON34881.1 - 4.5e-14 52.1 0.0 1.4e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EON34881.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminoglyc_resit PF10706.9 EON34881.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside-2''-adenylyltransferase Peptidase_M20 PF01546.28 EON34882.1 - 4.6e-37 127.7 2.6 5.4e-37 127.5 1.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EON34882.1 - 4.9e-18 65.0 0.0 8.4e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 EON34883.1 - 2.2e-32 112.4 36.9 2.2e-32 112.4 36.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EON34883.1 - 4.6e-32 111.5 26.9 7.4e-25 87.7 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 EON34883.1 - 7.8 5.2 15.7 0.14 10.9 6.2 2.0 2 0 0 2 2 2 0 LacY proton/sugar symporter FCD PF07729.12 EON34884.1 - 5.2e-24 85.0 13.4 5.2e-24 85.0 13.4 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 EON34884.1 - 5e-18 64.5 1.2 2.3e-17 62.4 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family PaaX PF07848.12 EON34884.1 - 0.0021 18.3 0.7 0.011 16.0 0.1 2.2 1 1 1 2 2 2 1 PaaX-like protein HTH_24 PF13412.6 EON34884.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TFIIE_alpha PF02002.17 EON34884.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_Crp_2 PF13545.6 EON34884.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EON34884.1 - 0.35 10.8 3.2 6.8 6.7 0.1 3.3 3 0 0 3 3 3 0 MarR family DUF3830 PF12903.7 EON34885.1 - 2.6e-61 205.6 0.0 3e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Amidase PF01425.21 EON34886.1 - 1.5e-100 337.3 0.0 4e-100 335.9 0.0 1.6 1 1 0 1 1 1 1 Amidase Amdase PF17645.1 EON34887.1 - 2.6e-20 73.0 0.1 3.2e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 EON34887.1 - 0.00077 19.4 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase MoCF_biosynth PF00994.24 EON34887.1 - 0.077 12.7 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Probable molybdopterin binding domain DUF222 PF02720.17 EON34888.1 - 4.8e-36 124.8 19.9 6.4e-36 124.4 17.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF222) DUF569 PF04601.13 EON34888.1 - 0.063 13.0 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF569) HNH PF01844.23 EON34888.1 - 0.12 12.6 0.4 0.22 11.8 0.4 1.5 1 0 0 1 1 1 0 HNH endonuclease CbiD PF01888.17 EON34888.1 - 0.42 9.9 1.0 1.4 8.1 0.2 1.9 1 1 0 2 2 2 0 CbiD APH_6_hur PF04655.14 EON34889.1 - 4.3e-49 167.2 5.0 5e-49 167.0 5.0 1.0 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 EON34889.1 - 2.6e-07 30.8 12.1 2.6e-07 30.8 12.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EON34889.1 - 4.3e-06 26.2 0.0 6.3e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Response_reg PF00072.24 EON34890.1 - 1.5e-26 92.7 0.0 2.1e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EON34890.1 - 1.2e-21 76.6 0.0 3.3e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Lipase_GDSL_2 PF13472.6 EON34890.1 - 0.019 15.3 0.4 0.03 14.7 0.4 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family KdpD PF02702.17 EON34891.1 - 2.5e-95 317.9 0.0 1.3e-94 315.6 0.0 2.1 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 EON34891.1 - 1.3e-28 98.9 11.3 2.8e-28 97.8 11.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 EON34891.1 - 3.7e-19 69.3 0.0 2.7e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EON34891.1 - 2.2e-11 43.6 0.3 9.6e-11 41.6 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 EON34891.1 - 2.9e-07 31.1 9.6 0.0013 19.3 0.3 3.7 3 1 1 4 4 4 2 Universal stress protein family KdpC PF02669.15 EON34892.1 - 3e-50 170.6 0.0 3.5e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain E1-E2_ATPase PF00122.20 EON34893.1 - 5.9e-35 120.4 5.0 5.9e-35 120.4 5.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EON34893.1 - 1.2e-33 117.1 2.0 2e-33 116.5 2.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EON34893.1 - 0.0006 20.3 0.0 0.002 18.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EON34893.1 - 0.0013 18.5 1.0 0.012 15.3 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF759 PF05537.11 EON34893.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) KdpA PF03814.15 EON34894.1 - 3.8e-199 662.4 29.9 9.9e-189 628.0 21.9 2.0 2 0 0 2 2 2 2 Potassium-transporting ATPase A subunit Potass_KdpF PF09604.10 EON34895.1 - 0.0019 18.1 8.0 0.0022 17.9 8.0 1.1 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) Putative_PNPOx PF01243.20 EON34896.1 - 1e-10 41.6 0.1 1.4e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EON34896.1 - 0.0037 17.3 0.0 0.0049 16.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Amdase PF17645.1 EON34897.1 - 8.6e-18 64.7 0.3 1.2e-17 64.3 0.3 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 EON34897.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Adenine_glyco PF03352.13 EON34898.1 - 1.1e-65 220.7 0.0 1.4e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Sigma70_r2 PF04542.14 EON34899.1 - 3.9e-14 52.2 0.6 7.9e-14 51.2 0.6 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EON34899.1 - 9.4e-14 50.8 0.1 1.9e-13 49.8 0.1 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EON34899.1 - 4.7e-12 45.2 0.5 4.7e-12 45.2 0.5 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EON34899.1 - 1.9e-09 37.7 0.5 3.1e-09 37.0 0.5 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_38 PF13936.6 EON34899.1 - 0.00029 20.5 0.8 0.034 13.9 0.0 2.7 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 EON34899.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EON34899.1 - 0.021 14.6 3.4 0.041 13.7 0.2 2.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 EON34899.1 - 0.061 13.5 2.2 0.42 10.8 0.0 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain AbiEi_1 PF09407.10 EON34899.1 - 0.078 13.3 0.1 0.83 10.0 0.0 2.1 1 1 1 2 2 2 0 AbiEi antitoxin C-terminal domain UPF0122 PF04297.14 EON34899.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TnsD PF15978.5 EON34899.1 - 0.16 11.0 0.0 0.33 9.9 0.0 1.6 1 1 0 1 1 1 0 Tn7-like transposition protein D IDH PF03971.14 EON34900.1 - 0 1244.7 0.0 0 1244.5 0.0 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DSBA PF01323.20 EON34901.1 - 0.00025 20.9 0.6 0.0011 18.8 0.6 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 EON34901.1 - 0.049 13.3 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin adh_short PF00106.25 EON34902.1 - 1.6e-43 148.4 0.0 2.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EON34902.1 - 1.5e-30 106.5 0.0 1.9e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EON34902.1 - 6e-10 39.3 0.0 8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EON34902.1 - 8.3e-07 29.1 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EON34902.1 - 0.00021 20.8 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EON34902.1 - 0.0049 16.3 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 EON34902.1 - 0.013 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2795 PF11387.8 EON34902.1 - 0.058 13.6 0.1 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) Katanin_con80 PF13925.6 EON34902.1 - 0.22 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 con80 domain of Katanin TetR_N PF00440.23 EON34904.1 - 2.6e-07 30.3 0.1 7.1e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 EON34904.1 - 3.3e-07 30.5 7.6 3.3e-07 30.5 7.6 2.3 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 EON34904.1 - 0.0053 17.2 2.9 0.0053 17.2 2.9 2.4 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 EON34904.1 - 0.0089 16.2 5.1 0.0089 16.2 5.1 3.5 1 1 2 3 3 3 1 BetI-type transcriptional repressor, C-terminal HTH_31 PF13560.6 EON34904.1 - 0.2 12.0 7.3 0.039 14.3 3.1 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain MFS_1 PF07690.16 EON34905.1 - 1.4e-41 142.6 47.5 1.4e-41 142.6 47.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EON34905.1 - 8.2e-05 21.6 5.3 8.2e-05 21.6 5.3 2.4 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 EON34905.1 - 0.001 18.0 35.6 0.0011 18.0 9.6 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter Pox_A14 PF05767.12 EON34905.1 - 0.011 15.9 1.5 0.3 11.3 0.0 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 ATG22 PF11700.8 EON34905.1 - 0.016 13.8 5.4 0.059 12.0 0.5 2.5 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like OATP PF03137.20 EON34905.1 - 0.48 8.6 5.8 0.026 12.8 0.4 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NMT1 PF09084.11 EON34906.1 - 4.3e-18 66.0 0.0 6.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON34906.1 - 2.4e-06 27.4 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EON34906.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON34906.1 - 0.0017 18.0 0.0 0.062 12.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 EON34906.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family VitK2_biosynth PF02621.14 EON34906.1 - 0.0049 16.4 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Menaquinone biosynthesis Aldolase_II PF00596.21 EON34907.1 - 5e-07 29.8 0.1 6e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Bac_luciferase PF00296.20 EON34908.1 - 2.1e-65 221.2 5.9 2.7e-65 220.9 5.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 EON34909.1 - 4.6e-34 118.3 12.0 5.6e-34 118.0 12.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NMT1 PF09084.11 EON34910.1 - 1.2e-06 28.6 0.0 0.0023 17.9 0.0 2.2 1 1 1 2 2 2 2 NMT1/THI5 like ABC_tran PF00005.27 EON34911.1 - 6.3e-27 94.8 0.0 1.2e-26 93.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EON34911.1 - 6e-07 30.0 0.4 9.6e-07 29.3 0.4 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EON34911.1 - 2.7e-06 27.4 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EON34911.1 - 0.00012 22.4 0.1 0.00025 21.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EON34911.1 - 0.00068 19.4 0.1 0.001 18.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EON34911.1 - 0.0008 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 EON34911.1 - 0.0021 18.3 1.0 0.0052 17.0 1.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EON34911.1 - 0.0036 17.5 0.1 0.0092 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EON34911.1 - 0.0073 15.9 1.1 0.015 14.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EON34911.1 - 0.0082 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 EON34911.1 - 0.014 15.4 0.1 0.037 14.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EON34911.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SMC_N PF02463.19 EON34911.1 - 0.035 13.6 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EON34911.1 - 0.046 14.3 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 EON34911.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SbcCD_C PF13558.6 EON34911.1 - 0.051 13.8 0.8 0.45 10.8 0.8 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EON34911.1 - 0.053 13.4 0.5 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EON34911.1 - 0.072 13.5 0.6 0.12 12.8 0.6 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EON34911.1 - 0.074 12.8 0.1 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 EON34911.1 - 0.082 13.4 0.1 0.12 12.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EON34911.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EON34911.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EON34911.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 EON34911.1 - 0.19 10.5 1.6 3.9 6.2 0.1 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 EON34911.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EON34911.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PduV-EutP PF10662.9 EON34911.1 - 0.23 11.2 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EON34911.1 - 0.25 10.8 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit BPD_transp_1 PF00528.22 EON34912.1 - 4.7e-22 78.6 11.8 4.7e-22 78.6 11.8 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 EON34912.1 - 0.15 12.4 2.6 0.41 11.0 1.0 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 NMT1 PF09084.11 EON34913.1 - 6.2e-16 59.0 0.1 7.9e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EON34913.1 - 4e-09 36.5 0.1 6.5e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 EON34913.1 - 4.7e-05 23.0 0.2 0.00015 21.3 0.1 2.0 1 1 1 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.20 EON34913.1 - 0.00038 19.9 0.0 0.00081 18.9 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EON34913.1 - 0.00039 20.1 2.0 0.00076 19.1 0.6 2.1 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein ABC_membrane PF00664.23 EON34914.1 - 3.7e-66 223.6 17.1 5.3e-35 121.4 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EON34914.1 - 3.8e-57 192.6 0.0 3.3e-28 98.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EON34914.1 - 1.2e-08 35.5 2.3 0.0014 19.0 0.1 3.2 3 0 0 3 3 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EON34914.1 - 1.4e-07 31.0 0.3 0.0021 17.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 EON34914.1 - 2.1e-07 31.3 0.2 0.062 13.6 0.1 3.4 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 EON34914.1 - 2.9e-06 26.9 0.3 0.092 12.2 0.0 3.8 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EON34914.1 - 2.3e-05 24.2 0.5 3.4 7.4 0.0 4.5 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_18 PF13238.6 EON34914.1 - 5.2e-05 23.8 0.1 0.54 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EON34914.1 - 7.8e-05 22.9 0.9 0.013 15.6 0.2 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EON34914.1 - 0.00013 21.9 0.2 0.59 9.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EON34914.1 - 0.00014 21.8 0.1 0.53 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EON34914.1 - 0.00029 20.6 1.9 0.49 10.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EON34914.1 - 0.0003 20.4 1.4 0.37 10.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EON34914.1 - 0.0016 18.0 0.1 0.43 10.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EON34914.1 - 0.0019 18.0 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EON34914.1 - 0.0023 18.0 0.3 1.4 9.0 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 EON34914.1 - 0.0029 17.3 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EON34914.1 - 0.0036 17.0 7.3 0.36 10.6 0.3 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA PF00004.29 EON34914.1 - 0.0047 17.4 0.0 0.21 12.0 0.0 2.7 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EON34914.1 - 0.0059 16.9 0.5 0.6 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EON34914.1 - 0.011 16.0 0.3 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain BCA_ABC_TP_C PF12399.8 EON34914.1 - 0.043 13.8 0.4 0.42 10.6 0.2 2.6 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 EON34914.1 - 0.05 14.1 1.4 4.9 7.6 0.4 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EON34914.1 - 0.088 13.2 0.0 19 5.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 EON34914.1 - 0.14 12.2 0.2 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EON34914.1 - 0.15 12.0 0.3 8.4 6.3 0.0 2.6 3 0 0 3 3 2 0 NTPase Cytidylate_kin PF02224.18 EON34914.1 - 0.16 11.7 0.3 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Cytidylate kinase CysA_C_terminal PF17850.1 EON34914.1 - 0.21 12.2 1.4 3.1 8.5 0.7 3.0 2 0 0 2 2 2 0 CysA C-terminal regulatory domain SbcCD_C PF13558.6 EON34914.1 - 0.32 11.3 3.2 1.2 9.4 0.0 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit IclR PF01614.18 EON34915.1 - 1.4e-19 70.2 0.0 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EON34915.1 - 6.9e-14 51.4 4.2 1.5e-13 50.3 0.9 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EON34915.1 - 2.1e-05 24.3 1.8 7.7e-05 22.5 0.4 2.3 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 EON34915.1 - 0.01 15.9 1.0 0.072 13.2 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 EON34915.1 - 0.018 14.9 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB SMC_Nse1 PF07574.13 EON34915.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex HTH_24 PF13412.6 EON34915.1 - 0.029 13.9 0.0 0.085 12.4 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 EON34915.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 MarR family DUF2087 PF09860.9 EON34915.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Dimerisation2 PF16864.5 EON34915.1 - 0.065 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Dimerisation domain Rrf2 PF02082.20 EON34915.1 - 0.099 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator TetR_C_14 PF17754.1 EON34916.1 - 3.5e-30 104.2 4.7 3.5e-30 104.2 4.7 1.8 1 1 1 2 2 2 1 MftR C-terminal domain TetR_N PF00440.23 EON34916.1 - 5.4e-15 54.9 0.3 1.8e-14 53.2 0.3 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 EON34916.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 EON34916.1 - 0.00026 21.1 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 EON34916.1 - 0.029 14.2 0.0 0.092 12.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain TrbI_Ftype PF09677.10 EON34916.1 - 0.035 14.4 0.4 0.054 13.8 0.4 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) HTH_AraC PF00165.23 EON34916.1 - 0.047 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family adh_short_C2 PF13561.6 EON34917.1 - 6.4e-48 163.3 8.6 6.9e-47 160.0 8.6 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EON34917.1 - 1.9e-46 158.0 5.3 1.1e-45 155.5 5.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EON34917.1 - 3.3e-13 50.0 2.2 4.8e-13 49.4 2.2 1.2 1 0 0 1 1 1 1 KR domain BenE PF03594.13 EON34917.1 - 0.054 12.3 3.0 0.072 11.9 3.0 1.1 1 0 0 1 1 1 0 Benzoate membrane transport protein DUF4140 PF13600.6 EON34917.1 - 0.13 12.7 0.9 5.1 7.6 0.6 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_5 PF07728.14 EON34918.1 - 2.3e-16 60.0 0.0 9.5e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EON34918.1 - 2.7e-10 40.2 0.0 5.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EON34918.1 - 0.009 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 EON34918.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EON34918.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain VWA_2 PF13519.6 EON34919.1 - 2e-08 34.8 0.0 4.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EON34919.1 - 5.2e-06 26.8 0.0 7.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EON34919.1 - 0.00015 21.2 0.4 0.00025 20.5 0.4 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 EON34919.1 - 0.01 15.7 0.3 0.028 14.4 0.1 1.9 2 1 0 2 2 2 0 von Willebrand factor type A domain CobT_C PF11775.8 EON34919.1 - 0.028 14.1 0.6 0.058 13.0 0.2 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Gordonia_terrae_C-6-C-6/GCA_000390025.1_C-6_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Gordonia_terrae_C-6-C-6/GCA_000390025.1_C-6_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Gordonia_terrae_C-6-C-6/GCA_000390025.1_C-6_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Gordonia_terrae_C-6-C-6/GCA_000390025.1_C-6_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:54:31 2019 # [ok]