# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DDE_5 PF13546.6 KEZ34179.1 - 5.6e-79 265.3 9.5 7.3e-79 264.9 9.5 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ34179.1 - 1.2e-12 48.0 0.0 3.4e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain Y1_Tnp PF01797.16 KEZ34181.1 - 1.9e-38 131.3 0.0 2.2e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Transposase IS200 like DUF4096 PF13340.6 KEZ34183.1 - 1.1e-24 86.4 0.7 1.5e-24 86.0 0.7 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 KEZ34184.1 - 1e-12 48.2 0.0 1.2e-12 48.1 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ34184.1 - 0.00067 19.4 0.1 0.0007 19.3 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 KEZ34184.1 - 0.018 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease TP2 PF01254.18 KEZ34184.1 - 0.086 13.4 0.2 0.11 13.2 0.2 1.1 1 0 0 1 1 1 0 Nuclear transition protein 2 Y1_Tnp PF01797.16 KEZ34185.1 - 3e-38 130.6 0.0 3.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS200 like OrfB_IS605 PF01385.19 KEZ34186.1 - 2.6e-22 79.3 0.3 4.9e-22 78.4 0.3 1.5 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 KEZ34186.1 - 4.1e-08 32.6 0.0 7.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain SpoIIE PF07228.12 KEZ34187.1 - 1.7e-43 148.8 2.4 2.7e-43 148.1 2.4 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PAS_4 PF08448.10 KEZ34187.1 - 1.1e-16 61.0 0.1 2.9e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 KEZ34187.1 - 8.5e-06 26.4 0.1 3.1e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KEZ34187.1 - 5.9e-05 23.4 3.2 0.00029 21.2 1.0 3.0 3 1 0 3 3 3 1 GAF domain GAF_3 PF13492.6 KEZ34187.1 - 0.00034 21.0 0.0 0.00083 19.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.7 KEZ34187.1 - 0.001 19.0 0.0 0.0031 17.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KEZ34187.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain Condensation PF00668.20 KEZ34188.1 - 5.8e-99 331.8 0.0 7.2e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KEZ34188.1 - 1.9e-15 57.0 0.1 7.2e-15 55.1 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site HicB PF05534.12 KEZ34188.1 - 0.051 13.4 0.2 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 HicB family NAD_kinase PF01513.21 KEZ34188.1 - 0.22 10.7 0.1 0.85 8.7 0.0 1.8 2 0 0 2 2 2 0 ATP-NAD kinase Condensation PF00668.20 KEZ34189.1 - 3.6e-77 260.0 0.0 4.7e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain HTH_3 PF01381.22 KEZ34191.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_38 PF13936.6 KEZ34191.1 - 0.0094 15.7 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ34191.1 - 0.034 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KEZ34191.1 - 0.05 14.0 0.3 0.11 12.9 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Condensation PF00668.20 KEZ34193.1 - 6e-76 256.0 0.0 6.7e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Condensation domain RHH_5 PF07878.11 KEZ34193.1 - 0.019 14.8 0.2 0.044 13.7 0.2 1.6 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 RHH_1 PF01402.21 KEZ34193.1 - 0.027 14.4 0.5 0.087 12.8 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Acetyltransf_1 PF00583.25 KEZ34195.1 - 5.8e-08 33.0 0.0 8.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ34195.1 - 7.5e-06 26.3 0.0 1.4e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ34195.1 - 7.6e-05 22.7 0.0 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ34195.1 - 0.0034 17.3 0.1 0.028 14.4 0.0 2.0 1 1 0 2 2 2 1 FR47-like protein RHH_1 PF01402.21 KEZ34197.1 - 6.9e-08 32.2 0.8 3.4e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family BrnA_antitoxin PF14384.6 KEZ34197.1 - 0.007 16.8 0.0 0.0098 16.4 0.0 1.3 1 0 0 1 1 1 1 BrnA antitoxin of type II toxin-antitoxin system NUDIX PF00293.28 KEZ34198.1 - 5.1e-17 62.2 0.1 6.4e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEZ34198.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain DDE_Tnp_IS66_C PF13817.6 KEZ34201.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 IS66 C-terminal element DUF3618 PF12277.8 KEZ34202.1 - 0.36 11.1 2.5 17 5.8 0.2 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3618) DDE_Tnp_1_assoc PF13808.6 KEZ34203.1 - 4.4e-24 84.3 0.0 1.1e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ34203.1 - 1.2e-10 41.4 0.2 1.6e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Transposase DDE domain RVT_1 PF00078.27 KEZ34205.1 - 2.2e-17 63.3 0.0 2.4e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1 PF01609.21 KEZ34206.1 - 1.7e-05 24.6 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain TPR_12 PF13424.6 KEZ34207.1 - 0.054 13.8 5.7 0.72 10.2 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ34207.1 - 0.36 10.8 3.3 0.41 10.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ34207.1 - 1.6 9.4 0.0 1.6 9.4 0.0 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ34207.1 - 7.5 7.7 7.7 4.1 8.5 0.3 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat Acetyltransf_3 PF13302.7 KEZ34208.1 - 2.2e-14 54.3 0.0 3.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ34208.1 - 1e-09 38.7 0.0 1.6e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEZ34208.1 - 1e-05 25.2 0.0 2.1e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ34208.1 - 0.00028 21.3 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ34208.1 - 0.0019 18.1 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KEZ34208.1 - 0.015 15.4 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ34208.1 - 0.044 13.7 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MerR PF00376.23 KEZ34208.1 - 0.045 13.5 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 MerR family regulatory protein UTRA PF07702.13 KEZ34209.1 - 1.7e-16 60.4 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 KEZ34209.1 - 1.3e-15 56.7 1.5 2.4e-15 55.9 1.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 KEZ34209.1 - 0.0015 18.7 0.6 0.0038 17.3 0.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ34209.1 - 0.0058 16.5 0.2 0.018 14.9 0.2 1.8 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 KEZ34209.1 - 0.0063 16.4 0.1 0.02 14.8 0.1 1.8 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 KEZ34209.1 - 0.02 15.0 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 KEZ34209.1 - 0.046 13.6 0.4 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KEZ34209.1 - 0.05 13.6 0.3 0.12 12.4 0.3 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Ribosomal_S19e PF01090.19 KEZ34209.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e LexA_DNA_bind PF01726.16 KEZ34209.1 - 0.14 12.0 0.5 0.76 9.6 0.2 2.2 2 0 0 2 2 2 0 LexA DNA binding domain HTH_12 PF08461.10 KEZ34209.1 - 0.15 12.1 0.8 1.9 8.5 0.3 2.7 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain OrfB_Zn_ribbon PF07282.11 KEZ34211.1 - 3.9e-23 81.1 0.1 5.4e-23 80.7 0.1 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 KEZ34211.1 - 0.00019 21.6 0.5 0.0003 21.0 0.5 1.3 1 0 0 1 1 1 1 Probable transposase C1_2 PF03107.16 KEZ34211.1 - 0.041 14.2 0.1 0.041 14.2 0.1 1.6 2 0 0 2 2 2 0 C1 domain DZR PF12773.7 KEZ34211.1 - 0.041 13.9 0.2 0.066 13.2 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF5596 PF18082.1 KEZ34211.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) TF_Zn_Ribbon PF08271.12 KEZ34211.1 - 0.42 10.2 4.7 1.7 8.2 4.7 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 KEZ34211.1 - 0.42 10.6 4.4 0.78 9.8 4.4 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_IS605 PF01385.19 KEZ34212.1 - 2.3e-20 73.0 0.5 3.4e-20 72.4 0.5 1.2 1 0 0 1 1 1 1 Probable transposase ParE_toxin PF05016.15 KEZ34213.1 - 5.8e-09 36.5 0.1 7e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE PhdYeFM_antitox PF02604.19 KEZ34214.1 - 9.4e-22 76.6 1.2 1.3e-21 76.2 0.3 1.6 2 0 0 2 2 2 1 Antitoxin Phd_YefM, type II toxin-antitoxin system HTH_33 PF13592.6 KEZ34218.1 - 3.1e-20 71.6 1.5 5.6e-20 70.7 1.5 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 KEZ34218.1 - 8.5e-12 45.5 0.5 1.2e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KEZ34218.1 - 2.3e-09 37.1 0.1 2.1e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KEZ34218.1 - 6.2e-09 35.9 0.6 6.4e-07 29.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.6 KEZ34218.1 - 5.1e-06 26.3 0.0 8.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 KEZ34218.1 - 7.5e-06 25.6 0.3 0.0001 22.0 0.0 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 KEZ34218.1 - 9.5e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Transposase Terminase_5 PF06056.12 KEZ34218.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.6 KEZ34218.1 - 0.018 15.5 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 YdaS_antitoxin PF15943.5 KEZ34218.1 - 0.027 14.3 0.0 0.098 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_50 PF18024.1 KEZ34218.1 - 0.17 11.5 0.0 1.3 8.7 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Condensation PF00668.20 KEZ34220.1 - 3.1e-80 270.1 0.0 3.7e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Condensation domain Condensation PF00668.20 KEZ34221.1 - 6e-30 104.3 0.0 8.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain Condensation PF00668.20 KEZ34222.1 - 3.9e-85 286.2 0.0 4.6e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KEZ34222.1 - 3.2e-32 111.7 0.6 4.8e-32 111.1 0.6 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ34222.1 - 7.4e-19 68.5 2.2 2.1e-18 67.1 0.7 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ34222.1 - 1.1e-15 57.7 0.3 9.5e-15 54.7 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site FGE-sulfatase PF03781.16 KEZ34223.1 - 1.4e-40 139.5 9.2 9.7e-39 133.5 9.2 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Condensation PF00668.20 KEZ34226.1 - 1.4e-92 310.7 0.0 1.8e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KEZ34226.1 - 1.4e-69 234.7 0.3 6.8e-69 232.5 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 KEZ34226.1 - 2.6e-12 46.9 0.0 1e-11 45.0 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Biotin_lipoyl PF00364.22 KEZ34228.1 - 4.2e-16 58.5 5.3 4.9e-16 58.3 5.3 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEZ34228.1 - 2.9e-10 39.8 5.6 9.9e-06 25.3 1.9 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 KEZ34228.1 - 0.00023 20.5 0.7 0.031 13.5 0.1 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KEZ34228.1 - 0.00076 20.2 4.5 0.021 15.5 0.5 2.0 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 KEZ34228.1 - 0.021 14.8 2.8 0.42 10.6 0.4 2.0 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 KEZ34228.1 - 0.032 14.0 0.1 3.5 7.4 0.0 2.0 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 KEZ34228.1 - 0.043 14.0 0.5 1.2 9.4 0.2 2.1 1 1 0 2 2 2 0 Peptidase family M23 Glyco_trans_1_4 PF13692.6 KEZ34228.1 - 0.048 14.1 0.5 0.053 13.9 0.5 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2118 PF09891.9 KEZ34228.1 - 0.098 12.6 0.2 5.3 7.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PYNP_C PF07831.13 KEZ34228.1 - 0.1 12.3 0.5 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF5317 PF17248.2 KEZ34229.1 - 9.8e-29 100.3 0.5 1.4e-28 99.8 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5317) zf-HC2 PF13490.6 KEZ34230.1 - 3.5e-10 39.9 1.9 8.4e-10 38.7 1.9 1.7 1 0 0 1 1 1 1 Putative zinc-finger Sigma70_r2 PF04542.14 KEZ34231.1 - 5e-20 71.0 0.7 9.9e-20 70.1 0.7 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ34231.1 - 5.8e-16 57.9 0.0 2e-15 56.2 0.0 2.0 1 1 1 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ34231.1 - 2.6e-10 39.7 0.2 1.2e-09 37.5 0.0 2.3 3 1 1 4 4 4 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KEZ34231.1 - 0.00023 21.1 0.1 0.00037 20.4 0.1 1.4 1 0 0 1 1 1 1 ECF sigma factor DDE_Tnp_1 PF01609.21 KEZ34232.1 - 3.7e-07 30.0 0.3 4.2e-07 29.8 0.3 1.1 1 0 0 1 1 1 1 Transposase DDE domain TIR_2 PF13676.6 KEZ34233.1 - 2.7e-31 108.6 0.0 3.7e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 TIR domain TPR_12 PF13424.6 KEZ34233.1 - 8.3e-10 38.8 2.6 1.3e-07 31.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ34233.1 - 6.3e-06 25.9 4.7 0.00022 21.0 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TIR PF01582.20 KEZ34233.1 - 0.035 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 TIR domain Resolvase PF00239.21 KEZ34236.1 - 8.4e-06 26.0 0.0 1.1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain Condensation PF00668.20 KEZ34237.1 - 2.6e-88 296.7 0.0 3.3e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KEZ34237.1 - 1.2e-63 215.2 6.6 6.4e-63 212.8 6.6 2.0 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KEZ34237.1 - 1.2e-13 51.2 0.3 2.8e-13 50.0 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ34237.1 - 3.1e-08 34.5 0.0 1.4e-07 32.4 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_tail_APC PF16778.5 KEZ34237.1 - 0.12 12.3 0.7 0.32 10.9 0.7 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone protein AMP-binding PF00501.28 KEZ34238.1 - 4e-75 253.0 0.4 7.3e-75 252.2 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KEZ34238.1 - 7.9e-37 127.0 0.0 3.5e-36 124.8 0.0 1.8 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KEZ34238.1 - 4.9e-14 52.4 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ34238.1 - 1.8e-12 48.0 1.5 1.8e-12 48.0 1.5 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TAL_effector PF03377.13 KEZ34238.1 - 0.089 13.1 0.1 0.089 13.1 0.1 2.0 2 0 0 2 2 2 0 TAL effector repeat Condensation PF00668.20 KEZ34239.1 - 1e-96 324.5 0.0 1.2e-96 324.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KEZ34239.1 - 1.7e-85 287.1 0.6 1.7e-85 287.1 0.6 2.2 3 0 0 3 3 3 1 AMP-binding enzyme PP-binding PF00550.25 KEZ34239.1 - 1.6e-15 57.2 0.2 3.8e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ34239.1 - 3e-11 44.1 0.5 3e-11 44.1 0.5 3.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Phage_integrase PF00589.22 KEZ34240.1 - 4.6e-15 55.8 0.9 1.5e-14 54.2 0.9 1.9 1 1 0 1 1 1 1 Phage integrase family Phage_integrase PF00589.22 KEZ34241.1 - 6.4e-22 78.1 0.0 8.6e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Acyl_transf_3 PF01757.22 KEZ34242.1 - 1.6e-13 50.5 29.3 2.1e-13 50.1 29.3 1.1 1 0 0 1 1 1 1 Acyltransferase family DDE_Tnp_IS66 PF03050.14 KEZ34243.1 - 4.7e-53 180.5 0.0 6.4e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family zf-IS66 PF13005.7 KEZ34243.1 - 1.8e-08 34.7 2.0 3.6e-08 33.7 2.0 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 KEZ34243.1 - 6.5e-06 26.8 0.8 3.1e-05 24.7 0.1 2.5 2 1 0 2 2 2 1 Transposase C of IS166 homeodomain DDE_Tnp_IS66_C PF13817.6 KEZ34243.1 - 0.00011 22.4 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 IS66 C-terminal element DDE_Tnp_ISL3 PF01610.17 KEZ34245.1 - 4.6e-16 59.3 0.0 6.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.11 KEZ34246.1 - 3.8e-144 479.4 0.0 4.7e-144 479.1 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain HTH_Tnp_4 PF13613.6 KEZ34246.1 - 0.0023 17.6 0.0 0.0061 16.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease PRIMA1 PF16101.5 KEZ34246.1 - 0.59 10.2 14.1 0.62 10.1 8.8 2.9 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 HTH_23 PF13384.6 KEZ34247.1 - 0.018 14.8 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.7 KEZ34247.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain TetR_C_15 PF17918.1 KEZ34250.1 - 0.039 14.7 0.4 0.075 13.8 0.4 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PIN PF01850.21 KEZ34251.1 - 6.6e-09 36.3 0.5 1.3e-08 35.4 0.5 1.4 1 1 0 1 1 1 1 PIN domain PhdYeFM_antitox PF02604.19 KEZ34252.1 - 0.00019 21.2 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system RNaseH_pPIWI_RE PF13032.6 KEZ34256.1 - 3.6e-53 181.4 10.5 5.6e-53 180.8 10.5 1.3 1 0 0 1 1 1 1 RNaseH domain of pPIWI_RE pPIWI_RE_X PF13111.6 KEZ34256.1 - 6.2e-33 114.6 8.4 1e-32 113.9 8.4 1.3 1 0 0 1 1 1 1 pPIWI_RE module N-terminal domain MID_pPIWI_RE PF18157.1 KEZ34256.1 - 3.9e-08 33.7 0.0 1.1e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 MID domain of pPIWI_RE DUF2397 PF09660.10 KEZ34258.1 - 0.0026 16.7 0.0 0.0074 15.2 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2397) DUF2397 PF09660.10 KEZ34259.1 - 0.024 13.6 0.0 0.051 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2397) DZR PF12773.7 KEZ34260.1 - 0.045 13.8 1.4 0.045 13.8 1.4 1.7 2 0 0 2 2 2 0 Double zinc ribbon zf-FLZ PF04570.14 KEZ34260.1 - 1.2 8.7 4.1 1.3 8.6 0.1 2.7 4 0 0 4 4 4 0 zinc-finger of the FCS-type, C2-C2 AAA_33 PF13671.6 KEZ34261.1 - 7.2e-06 26.2 0.1 1.2e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEZ34261.1 - 4.2e-05 23.9 0.1 7.2e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ34261.1 - 0.00012 22.6 0.0 0.0002 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 KEZ34261.1 - 0.0004 20.5 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 Adenylate kinase MRP_L53 PF10780.9 KEZ34261.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 AAA_16 PF13191.6 KEZ34261.1 - 0.061 13.7 0.4 0.26 11.7 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KEZ34261.1 - 0.074 12.6 1.6 1.9 8.0 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KEZ34261.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEZ34261.1 - 0.098 13.1 0.0 0.39 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KEZ34261.1 - 0.11 12.2 0.0 9.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KEZ34261.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NinD PF17466.2 KEZ34261.1 - 0.24 11.5 2.0 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function IlvB_leader PF08049.11 KEZ34261.1 - 1.7 8.6 8.5 0.15 12.0 2.0 2.7 2 0 0 2 2 2 0 IlvB leader peptide DUF35_N PF12172.8 KEZ34261.1 - 4 7.4 9.8 0.58 10.1 1.7 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Radical_SAM PF04055.21 KEZ34262.1 - 2.1e-18 67.3 0.0 3.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ34262.1 - 5.1e-05 23.6 0.0 9.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ34262.1 - 0.00065 19.8 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain Dehyd-heme_bind PF09098.10 KEZ34262.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding PfkB PF00294.24 KEZ34264.1 - 2e-16 60.2 0.0 2.7e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4096 PF13340.6 KEZ34265.1 - 4.3e-25 87.7 0.2 4.8e-25 87.6 0.2 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) HTH_3 PF01381.22 KEZ34266.1 - 0.00042 20.3 1.0 0.0052 16.8 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 KEZ34266.1 - 0.009 16.3 0.0 0.009 16.3 0.0 3.9 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ34266.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Cohesin_HEAT PF12765.7 KEZ34266.1 - 0.072 13.4 0.6 0.14 12.5 0.6 1.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion TPR_6 PF13174.6 KEZ34266.1 - 0.13 13.0 1.9 1.3 9.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KEZ34267.1 - 7.7e-28 97.4 0.9 3.3e-19 69.1 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ34267.1 - 9.1e-20 71.4 0.0 5.1e-15 55.8 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ34267.1 - 8.5e-16 59.2 5.8 1.4e-15 58.5 5.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KEZ34267.1 - 5e-09 36.0 0.1 3.1e-06 26.9 0.1 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KEZ34267.1 - 5.5e-06 26.4 0.2 5.5e-06 26.4 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ34267.1 - 6.3e-05 22.6 0.0 0.0008 18.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEZ34267.1 - 0.00031 20.4 0.0 0.014 15.0 0.0 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.12 KEZ34267.1 - 0.00091 19.2 0.0 0.0043 17.0 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 KEZ34267.1 - 0.0061 16.3 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KEZ34267.1 - 0.0094 15.6 0.0 0.082 12.5 0.0 2.0 1 1 1 2 2 2 1 Putative esterase FSH1 PF03959.13 KEZ34267.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KEZ34267.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HATPase_c_2 PF13581.6 KEZ34268.1 - 7.2e-12 45.4 0.1 1e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ34268.1 - 0.023 15.2 0.0 0.051 14.1 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Resolvase PF00239.21 KEZ34269.1 - 0.009 16.1 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain DDE_5 PF13546.6 KEZ34270.1 - 2e-20 73.3 0.1 2e-20 73.3 0.1 1.7 2 1 1 3 3 3 1 DDE superfamily endonuclease Rad50_zn_hook PF04423.14 KEZ34271.1 - 0.019 14.8 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Rad50 zinc hook motif TRAF6_Z2 PF18048.1 KEZ34271.1 - 0.031 14.3 1.1 0.041 14.0 1.1 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2 PF00096.26 KEZ34271.1 - 0.084 13.4 0.1 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2256 PF10013.9 KEZ34271.1 - 0.093 12.9 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) RHH_1 PF01402.21 KEZ34272.1 - 1.1e-05 25.1 5.9 1.1e-05 25.1 5.9 1.8 2 1 0 2 2 2 1 Ribbon-helix-helix protein, copG family NuDC PF16273.5 KEZ34272.1 - 0.076 13.5 1.5 0.097 13.2 1.5 1.3 1 0 0 1 1 1 0 Nuclear distribution C domain Fic PF02661.18 KEZ34273.1 - 5.3e-07 30.4 0.0 7.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Fic/DOC family DUF433 PF04255.14 KEZ34274.1 - 1.9e-08 34.0 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF433) HTH_17 PF12728.7 KEZ34274.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 KEZ34274.1 - 0.17 12.0 4.0 0.37 10.9 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain PIN_10 PF18478.1 KEZ34275.1 - 6.1e-09 36.0 0.0 8.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 PIN like domain Phage_integrase PF00589.22 KEZ34276.1 - 1e-22 80.7 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family LZ_Tnp_IS66 PF13007.7 KEZ34277.1 - 2.9e-05 24.8 1.7 5e-05 24.0 0.1 2.1 2 1 0 2 2 2 1 Transposase C of IS166 homeodomain MscS_porin PF12795.7 KEZ34277.1 - 0.005 16.4 0.8 0.0058 16.2 0.8 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain ATG16 PF08614.11 KEZ34277.1 - 0.033 14.4 1.0 0.037 14.2 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TPD52 PF04201.15 KEZ34277.1 - 0.11 12.1 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Tumour protein D52 family bZIP_2 PF07716.15 KEZ34277.1 - 0.13 12.3 5.4 3.2 7.9 3.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper NACHT PF05729.12 KEZ34278.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KEZ34278.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Bac_luciferase PF00296.20 KEZ34279.1 - 9.7e-27 94.2 0.9 2.6e-26 92.8 0.2 1.8 1 1 0 2 2 2 1 Luciferase-like monooxygenase Aminotran_3 PF00202.21 KEZ34280.1 - 5.4e-85 285.5 0.0 6.7e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF4213 PF13938.6 KEZ34280.1 - 0.19 11.9 3.0 0.3 11.4 1.0 2.4 2 1 0 2 2 2 0 Putative heavy-metal chelation DraK_HK_N PF18092.1 KEZ34280.1 - 1.7 9.1 5.3 5.8 7.4 0.9 2.6 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain DDE_Tnp_IS66 PF03050.14 KEZ34281.1 - 1.2e-28 100.5 0.0 1.5e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family zf-IS66 PF13005.7 KEZ34281.1 - 0.0001 22.6 0.5 0.00018 21.8 0.5 1.4 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 Cep57_CLD_2 PF14197.6 KEZ34282.1 - 0.015 15.4 5.0 0.016 15.3 3.0 2.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Resolvase PF00239.21 KEZ34284.1 - 2e-18 66.9 1.8 4e-18 65.9 1.8 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 KEZ34284.1 - 3.4e-13 49.9 0.0 6.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 KEZ34284.1 - 0.0035 17.8 7.0 0.0045 17.5 3.5 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf-RRN7 PF11781.8 KEZ34284.1 - 6.9 6.4 5.9 0.92 9.2 0.1 2.6 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DiS_P_DiS PF06750.13 KEZ34285.1 - 0.054 13.6 0.2 0.054 13.6 0.2 1.2 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain ROK PF00480.20 KEZ34286.1 - 2.4e-46 158.5 0.0 2.8e-42 145.2 0.0 2.0 2 0 0 2 2 2 2 ROK family BcrAD_BadFG PF01869.20 KEZ34286.1 - 0.00068 19.2 0.1 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Clp_N PF02861.20 KEZ34286.1 - 0.12 12.5 1.0 7.1 6.8 0.4 2.4 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component FGGY_N PF00370.21 KEZ34286.1 - 0.23 11.0 0.0 1.3 8.6 0.0 1.9 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Condensation PF00668.20 KEZ34287.1 - 6.9e-166 552.4 0.0 1.2e-88 297.8 0.0 2.0 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 KEZ34287.1 - 5e-99 331.8 4.3 6.2e-87 291.9 0.3 2.4 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ34287.1 - 6.4e-16 59.1 0.9 4.1e-15 56.5 0.6 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ34287.1 - 5.6e-13 49.0 0.3 1.9e-12 47.3 0.2 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site SH3_9 PF14604.6 KEZ34288.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain BLOC1_2 PF10046.9 KEZ34290.1 - 0.016 15.4 0.0 0.46 10.8 0.0 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSBP1 PF06825.12 KEZ34290.1 - 0.017 15.0 0.0 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tropomyosin PF00261.20 KEZ34290.1 - 0.017 14.5 0.6 0.68 9.3 0.1 2.0 1 1 1 2 2 2 0 Tropomyosin MRF_C1 PF13887.6 KEZ34290.1 - 0.042 13.0 0.2 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DUF4164 PF13747.6 KEZ34290.1 - 0.05 13.9 0.9 0.09 13.1 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.13 KEZ34290.1 - 0.061 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region MeaB PF03308.16 KEZ34292.1 - 0.072 12.1 0.1 0.072 12.1 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4730 PF15873.5 KEZ34294.1 - 0.022 15.0 0.3 0.027 14.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) Resolvase PF00239.21 KEZ34295.1 - 2.6e-10 40.6 0.0 5.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 KEZ34295.1 - 2.4e-09 37.6 0.9 5.4e-09 36.4 0.9 1.6 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 KEZ34295.1 - 4.4e-07 30.2 0.0 1.3e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Recombinase Img2 PF05046.14 KEZ34295.1 - 0.082 13.2 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DDE_Tnp_4 PF13359.6 KEZ34296.1 - 1.3e-21 76.9 0.0 1.6e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ34296.1 - 0.00014 21.6 0.1 0.00023 20.9 0.1 1.4 1 1 0 1 1 1 1 Transposase DDE domain Thymidylate_kin PF02223.17 KEZ34297.1 - 5.4e-29 101.2 0.0 6.6e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 KEZ34297.1 - 5.9e-07 29.7 0.4 8.6e-06 26.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ34297.1 - 9.5e-07 29.4 0.0 3.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEZ34297.1 - 1.3e-05 25.5 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KEZ34297.1 - 2.1e-05 24.5 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_30 PF13604.6 KEZ34297.1 - 6.6e-05 22.7 0.0 7.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ34297.1 - 0.00012 22.6 0.1 0.00018 22.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KEZ34297.1 - 0.00017 21.4 0.1 0.00027 20.8 0.1 1.3 1 0 0 1 1 1 1 Cytidylate kinase ABC_tran PF00005.27 KEZ34297.1 - 0.00025 21.6 0.0 0.00032 21.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KEZ34297.1 - 0.00028 21.2 0.0 0.00039 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KEZ34297.1 - 0.00081 18.4 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KEZ34297.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.6 KEZ34297.1 - 0.0013 19.1 0.0 0.86 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KEZ34297.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 KEZ34297.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KEZ34297.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 KEZ34297.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PIF1 PF05970.14 KEZ34297.1 - 0.024 13.8 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase ATP_bind_1 PF03029.17 KEZ34297.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KEZ34297.1 - 0.042 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KEZ34297.1 - 0.052 13.6 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KEZ34297.1 - 0.056 13.8 0.0 0.083 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 KEZ34297.1 - 0.056 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KEZ34297.1 - 0.059 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KEZ34297.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 KEZ34297.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Rad17 PF03215.15 KEZ34297.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KEZ34297.1 - 0.11 12.1 0.1 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEZ34297.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 KEZ34297.1 - 0.2 11.3 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Glyco_trans_4_4 PF13579.6 KEZ34297.1 - 0.3 11.5 6.0 0.71 10.3 6.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain RNase_T PF00929.24 KEZ34298.1 - 2e-16 61.0 0.0 2.7e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KEZ34298.1 - 7.8e-05 22.5 0.0 0.0002 21.1 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease CAF1 PF04857.20 KEZ34298.1 - 0.11 11.7 0.0 1.8 7.7 0.0 2.0 1 1 1 2 2 2 0 CAF1 family ribonuclease Radical_SAM PF04055.21 KEZ34299.1 - 3.1e-06 27.7 0.6 7.8e-06 26.4 0.1 2.0 2 1 0 2 2 2 1 Radical SAM superfamily HTH_31 PF13560.6 KEZ34300.1 - 9.8e-06 25.8 0.7 5.9e-05 23.3 0.3 2.5 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34300.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix DUF4123 PF13503.6 KEZ34300.1 - 0.01 16.3 0.5 0.021 15.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Death PF00531.22 KEZ34300.1 - 0.081 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Death domain HTH_19 PF12844.7 KEZ34300.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain BTAD PF03704.17 KEZ34305.1 - 7.2e-35 120.6 3.7 1.1e-34 119.9 3.7 1.3 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KEZ34305.1 - 5.2e-08 32.9 0.1 1.2e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal TPR_11 PF13414.6 KEZ34305.1 - 0.055 13.2 1.4 0.11 12.2 1.4 1.4 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KEZ34305.1 - 0.056 13.6 0.8 0.15 12.2 0.8 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ34305.1 - 0.3 11.0 1.0 1.5 8.8 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MLTR_LBD PF17765.1 KEZ34307.1 - 1.3e-32 113.2 1.5 2e-32 112.6 1.5 1.3 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KEZ34307.1 - 6.8e-10 39.2 1.8 6.8e-10 39.2 1.8 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34307.1 - 1e-09 38.3 0.1 2e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ34307.1 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain SnoaL_2 PF12680.7 KEZ34308.1 - 5e-15 56.0 0.9 5.8e-15 55.8 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KEZ34308.1 - 0.00083 19.2 0.1 0.0063 16.3 0.1 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KEZ34308.1 - 0.003 17.9 0.5 0.0038 17.6 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 KEZ34308.1 - 0.011 15.9 0.1 0.016 15.3 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain MARVEL PF01284.23 KEZ34309.1 - 9.6 6.2 12.0 2.1 8.4 0.4 2.2 1 1 1 2 2 2 0 Membrane-associating domain DEDD_Tnp_IS110 PF01548.17 KEZ34310.1 - 7.1e-10 39.0 0.0 1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KEZ34311.1 - 0.014 15.2 0.2 0.065 13.0 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Transposase_20 PF02371.16 KEZ34312.1 - 1.2e-19 70.4 1.0 2.5e-19 69.4 1.0 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 KEZ34312.1 - 8.6e-18 64.7 0.3 8.3e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Transposase DUF4096 PF13340.6 KEZ34313.1 - 7.7e-20 70.9 0.1 8.6e-20 70.7 0.1 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_assoc PF13808.6 KEZ34314.1 - 1.1e-18 67.0 0.4 4.9e-18 64.9 0.1 2.3 3 0 0 3 3 3 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ34314.1 - 1.9e-10 40.8 0.0 2.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain UTRA PF07702.13 KEZ34314.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 UTRA domain DDE_Tnp_ISAZ013 PF07592.11 KEZ34315.1 - 5e-138 459.2 0.0 6.2e-138 458.9 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain LacI PF00356.21 KEZ34315.1 - 0.18 11.6 0.4 0.48 10.3 0.4 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Rimk_N PF18030.1 KEZ34315.1 - 0.22 11.9 0.0 15 6.1 0.0 2.3 2 0 0 2 2 2 0 RimK PreATP-grasp domain DDE_5 PF13546.6 KEZ34317.1 - 9.2e-60 202.3 2.6 9.2e-60 202.3 2.6 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ34317.1 - 0.0014 18.4 0.0 0.017 14.7 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_IS66 PF03050.14 KEZ34318.1 - 3.1e-08 33.4 0.0 3.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 KEZ34318.1 - 0.0073 16.5 0.1 0.016 15.4 0.1 1.6 1 1 0 1 1 1 1 IS66 C-terminal element RVT_1 PF00078.27 KEZ34319.1 - 4.6e-42 144.0 0.0 5.6e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_tranf_2_4 PF13704.6 KEZ34319.1 - 0.01 16.3 0.1 0.036 14.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2300 PF10062.9 KEZ34319.1 - 0.1 12.7 0.3 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) HTH_17 PF12728.7 KEZ34320.1 - 5.2e-10 39.3 1.1 0.0014 18.8 0.0 2.9 2 1 1 3 3 3 2 Helix-turn-helix domain HTH_28 PF13518.6 KEZ34320.1 - 1.4e-07 31.5 0.7 0.017 15.3 0.1 3.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KEZ34320.1 - 9.9e-06 25.2 2.0 0.15 11.9 0.0 3.8 3 1 0 3 3 3 2 Homeodomain-like domain AbiEi_4 PF13338.6 KEZ34320.1 - 0.0014 18.7 0.1 0.82 9.9 0.1 3.0 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin MerR PF00376.23 KEZ34320.1 - 0.0015 18.3 0.7 2.5 8.0 0.0 2.9 2 1 0 2 2 2 2 MerR family regulatory protein ANT PF03374.14 KEZ34320.1 - 0.0015 18.8 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Phage antirepressor protein KilAC domain Sigma70_r4_2 PF08281.12 KEZ34320.1 - 0.0058 16.3 0.0 1.4 8.6 0.0 3.1 2 1 0 2 2 2 1 Sigma-70, region 4 MerR_1 PF13411.6 KEZ34320.1 - 0.014 15.4 0.1 6.5 6.9 0.0 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein YdaS_antitoxin PF15943.5 KEZ34320.1 - 0.05 13.5 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT P22_Cro PF14549.6 KEZ34320.1 - 0.067 13.1 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro COE1_HLH PF16423.5 KEZ34320.1 - 0.077 12.7 0.3 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain HTH_Tnp_IS630 PF01710.16 KEZ34320.1 - 0.24 11.5 0.2 5.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE_Tnp_ISL3 PF01610.17 KEZ34322.1 - 5.7e-48 163.7 0.1 7.1e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 Transposase DUF1748 PF08520.10 KEZ34322.1 - 0.025 14.5 0.3 0.067 13.1 0.3 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Phage_integrase PF00589.22 KEZ34324.1 - 8.3e-28 97.3 0.0 1.5e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ34324.1 - 3.7e-12 46.4 0.3 3.4e-11 43.3 0.3 2.3 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KEZ34324.1 - 0.00015 22.2 0.0 0.00074 19.9 0.0 2.1 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF4096 PF13340.6 KEZ34325.1 - 7.7e-27 93.3 0.1 8.7e-27 93.1 0.1 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) HTH_Tnp_1 PF01527.20 KEZ34326.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Transposase Transposase_20 PF02371.16 KEZ34327.1 - 8.5e-24 83.7 0.2 1.8e-23 82.7 0.2 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 KEZ34327.1 - 3.8e-20 72.3 0.0 6.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Transposase 5_3_exonuc PF01367.20 KEZ34327.1 - 0.12 13.0 0.1 0.5 11.0 0.0 2.0 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Flg_hook PF02120.16 KEZ34327.1 - 0.13 12.1 0.8 19 5.3 0.1 2.4 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK MerR-DNA-bind PF09278.11 KEZ34327.1 - 0.36 11.4 10.7 0.44 11.1 0.3 3.8 4 0 0 4 4 4 0 MerR, DNA binding HTH_Tnp_4 PF13613.6 KEZ34328.1 - 2.8e-08 33.4 0.0 4.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease BTAD PF03704.17 KEZ34330.1 - 4.3e-40 137.5 8.9 4.3e-40 137.5 8.9 3.6 4 0 0 4 4 3 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 KEZ34330.1 - 9.5e-31 105.9 38.9 4.4e-10 39.7 0.7 6.7 3 1 3 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ34330.1 - 1.7e-15 55.8 15.4 0.0096 16.0 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ34330.1 - 7.3e-14 51.1 23.1 3.3e-05 23.6 0.1 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ34330.1 - 1.7e-13 49.5 20.4 0.082 13.0 0.1 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ34330.1 - 1.4e-12 46.8 13.0 0.0029 17.4 0.0 7.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ34330.1 - 4.3e-12 45.2 8.1 0.036 14.3 0.0 7.2 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ34330.1 - 3.3e-11 43.2 26.0 4.5e-08 32.8 5.6 3.7 2 1 1 3 3 3 2 MalT-like TPR region Trans_reg_C PF00486.28 KEZ34330.1 - 7.6e-09 35.5 0.0 1.9e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal AAA_16 PF13191.6 KEZ34330.1 - 1.4e-06 28.8 0.0 1.4e-06 28.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KEZ34330.1 - 3.9e-05 23.0 0.0 0.043 13.0 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain IstB_IS21 PF01695.17 KEZ34330.1 - 0.00015 21.6 0.1 0.007 16.1 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein TPR_16 PF13432.6 KEZ34330.1 - 0.00022 21.8 35.3 0.0078 16.8 0.7 7.2 5 3 1 6 6 4 3 Tetratricopeptide repeat AAA_22 PF13401.6 KEZ34330.1 - 0.00068 19.9 0.0 0.003 17.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEZ34330.1 - 0.0059 16.4 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KEZ34330.1 - 0.0079 16.1 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 1 NACHT domain RPN7 PF10602.9 KEZ34330.1 - 0.011 15.4 2.0 5.4 6.7 0.1 3.4 2 1 1 3 3 3 0 26S proteasome subunit RPN7 AAA_33 PF13671.6 KEZ34330.1 - 0.03 14.5 0.0 0.13 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ34330.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_9 PF13371.6 KEZ34330.1 - 0.048 13.8 9.4 0.27 11.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_25 PF13481.6 KEZ34330.1 - 0.067 12.8 0.1 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_6 PF13174.6 KEZ34330.1 - 0.13 13.0 18.8 9.1 7.2 0.6 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KEZ34330.1 - 0.14 12.3 8.3 31 4.7 0.1 4.4 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 KEZ34330.1 - 0.81 10.5 40.2 1.5 9.7 0.1 9.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ34330.1 - 3.3 8.3 6.6 93 3.8 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DDE_Tnp_1_assoc PF13808.6 KEZ34332.1 - 6.7e-16 58.1 0.0 8.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 DDE_Tnp_1-associated Optomotor-blind PF11078.8 KEZ34332.1 - 0.059 13.9 2.3 0.073 13.6 2.3 1.1 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region NUDIX PF00293.28 KEZ34333.1 - 1.6e-07 31.5 0.6 2.3e-07 30.9 0.6 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4637 PF15470.6 KEZ34333.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TrwB_AAD_bind PF10412.9 KEZ34334.1 - 0.12 11.3 0.3 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 KEZ34334.1 - 0.17 11.3 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 KEZ34334.1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KEZ34334.1 - 0.34 11.2 1.8 0.58 10.5 1.9 1.6 1 1 0 1 1 1 0 AAA domain Phage_integrase PF00589.22 KEZ34335.1 - 7.8e-38 129.9 0.0 1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 KEZ34335.1 - 1e-06 29.1 0.0 4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KEZ34335.1 - 7.1e-05 23.0 0.4 0.00031 21.0 0.4 2.1 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain MLTR_LBD PF17765.1 KEZ34336.1 - 0.0086 16.2 0.1 0.0099 16.0 0.1 1.1 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain N6_N4_Mtase PF01555.18 KEZ34337.1 - 8.9e-53 179.4 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_11 PF08241.12 KEZ34337.1 - 0.0047 17.5 0.0 0.57 10.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DUF4129 PF13559.6 KEZ34337.1 - 0.17 12.2 3.3 1.5 9.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) DDE_Tnp_Tn3 PF01526.17 KEZ34339.1 - 6.6e-84 281.9 0.0 3.9e-71 239.9 0.0 2.2 1 1 1 2 2 2 2 Tn3 transposase DDE domain DUF4158 PF13700.6 KEZ34339.1 - 3.9e-54 182.9 0.1 8.6e-54 181.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) NAD_kinase PF01513.21 KEZ34340.1 - 1.9e-57 194.7 0.0 2.3e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase PDGLE PF13190.6 KEZ34340.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain FtsJ PF01728.19 KEZ34341.1 - 3.2e-20 73.0 0.0 4.1e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 KEZ34341.1 - 1.8e-09 37.2 0.1 4e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 S4 domain Methyltransf_11 PF08241.12 KEZ34341.1 - 0.13 12.9 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Alkyl_sulf_C PF14864.6 KEZ34343.1 - 2.7e-08 34.1 0.0 2.8e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2 PF02036.17 KEZ34343.1 - 9e-06 26.1 0.0 1e-05 26.0 0.0 1.3 1 1 0 1 1 1 1 SCP-2 sterol transfer family MDMPI_C PF07398.11 KEZ34343.1 - 0.099 13.5 5.2 0.71 10.8 5.2 2.2 1 1 0 1 1 1 0 MDMPI C-terminal domain Hydrolase_6 PF13344.6 KEZ34344.1 - 5.5e-21 74.6 0.0 9.8e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ34344.1 - 1.2e-14 54.1 0.3 2.3e-13 50.0 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like GNAT_like PF18407.1 KEZ34344.1 - 0.00035 20.9 3.3 0.00035 20.9 3.3 3.6 3 0 0 3 3 3 1 GCN5-related N-acetyltransferase like domain Hydrolase PF00702.26 KEZ34344.1 - 0.00045 20.6 0.8 0.04 14.2 0.8 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 KEZ34345.1 - 1.4e-08 35.1 6.0 2.5e-08 34.3 0.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ34345.1 - 2e-08 34.7 17.4 4.8e-07 30.3 3.7 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ34345.1 - 7.8e-07 29.4 11.4 0.00049 20.7 0.2 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ34345.1 - 8.5e-07 28.6 3.4 0.15 12.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ34345.1 - 8.9e-06 26.0 1.4 0.41 11.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ34345.1 - 1.8e-05 24.5 0.0 1.4 9.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ34345.1 - 2.3e-05 24.5 7.9 0.00058 20.0 1.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KEZ34345.1 - 0.00069 19.9 1.4 0.02 15.2 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ34345.1 - 0.0012 19.1 0.2 4.1 8.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ34345.1 - 0.0026 17.5 0.1 0.62 10.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ34345.1 - 0.0077 15.5 0.2 0.0098 15.1 0.2 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ34345.1 - 0.013 15.8 6.4 1.5 9.2 0.1 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.6 KEZ34345.1 - 0.023 14.4 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein Alkyl_sulf_dimr PF14863.6 KEZ34345.1 - 0.042 14.3 0.1 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 KEZ34345.1 - 0.06 14.0 0.8 0.06 14.0 0.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ34345.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1015 PF06245.11 KEZ34346.1 - 1.4e-120 402.8 0.0 1.6e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) TPR_19 PF14559.6 KEZ34347.1 - 3.1e-06 27.6 10.6 0.00026 21.4 0.8 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ34347.1 - 5.6e-06 26.9 27.1 0.0029 18.2 5.8 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ34347.1 - 4.4e-05 23.3 8.8 0.0098 15.9 0.7 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_5 PF12688.7 KEZ34347.1 - 0.00027 21.2 0.1 0.0013 19.0 0.0 2.2 1 1 1 2 2 2 1 Tetratrico peptide repeat TPR_12 PF13424.6 KEZ34347.1 - 0.00027 21.1 10.0 0.00065 19.9 0.2 3.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ34347.1 - 0.0005 20.7 31.8 0.0028 18.3 5.0 5.4 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ34347.1 - 0.0045 17.5 5.0 0.0045 17.5 5.0 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ34347.1 - 0.0069 16.6 0.1 5.6 7.3 0.0 2.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KEZ34347.1 - 0.042 14.2 3.0 0.32 11.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ34347.1 - 0.16 12.5 0.7 2.4 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ34347.1 - 6 7.1 17.8 13 6.1 2.5 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.28 KEZ34348.1 - 1.7e-27 96.1 1.2 1.9e-27 96.0 1.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme MbtH PF03621.13 KEZ34349.1 - 5.9e-29 99.3 0.1 7.3e-29 99.0 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein Aminotran_1_2 PF00155.21 KEZ34350.1 - 1.4e-23 83.7 0.0 1.7e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KEZ34350.1 - 9e-10 37.9 0.0 3.6e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KEZ34350.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PDH PF02153.17 KEZ34351.1 - 6.4e-59 199.0 0.0 7.9e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KEZ34351.1 - 2.5e-06 28.0 0.2 6.8e-06 26.6 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KEZ34351.1 - 6e-05 23.0 0.2 0.00021 21.2 0.2 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KEZ34351.1 - 0.00029 20.8 2.2 0.27 11.2 0.1 2.5 2 1 0 2 2 2 2 Zinc-binding dehydrogenase DAO PF01266.24 KEZ34351.1 - 0.00048 19.8 6.7 0.00081 19.1 6.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KEZ34351.1 - 0.003 17.2 0.7 0.0072 16.0 0.4 1.9 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KEZ34351.1 - 0.0031 16.8 0.3 0.0088 15.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ34351.1 - 0.01 16.4 0.1 0.023 15.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 KEZ34351.1 - 0.016 15.3 0.4 0.073 13.1 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_8 PF13450.6 KEZ34351.1 - 0.018 15.2 4.9 0.036 14.3 1.5 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KEZ34351.1 - 0.02 15.1 2.8 0.041 14.1 0.0 2.5 3 0 0 3 3 2 0 TrkA-N domain NAD_binding_2 PF03446.15 KEZ34351.1 - 0.026 14.7 0.0 0.066 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KEZ34351.1 - 0.028 13.7 0.6 0.048 13.0 0.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KEZ34351.1 - 0.034 14.1 0.1 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 KEZ34351.1 - 0.04 13.0 10.3 0.18 10.8 10.3 1.9 1 1 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.6 KEZ34351.1 - 0.051 13.1 0.8 0.18 11.3 0.1 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 KEZ34351.1 - 0.08 12.3 0.5 0.23 10.8 0.1 2.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KEZ34351.1 - 0.27 10.3 1.4 0.39 9.8 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CoA_binding_2 PF13380.6 KEZ34351.1 - 0.54 10.8 3.6 0.75 10.3 0.7 2.5 2 1 0 2 2 2 0 CoA binding domain Glyoxalase_4 PF13669.6 KEZ34352.1 - 2.6e-22 79.1 0.1 1.9e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KEZ34352.1 - 3.3e-20 72.6 0.1 4.8e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KEZ34352.1 - 8.2e-12 45.5 0.1 1.3e-08 35.1 0.1 2.3 2 0 0 2 2 2 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KEZ34352.1 - 2.8e-07 30.8 5.9 0.0079 16.3 0.4 3.3 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KEZ34352.1 - 0.0034 18.1 2.5 2.5 8.9 0.9 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain ECH_1 PF00378.20 KEZ34353.1 - 3.1e-65 220.0 0.0 3.5e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ34353.1 - 8.3e-34 117.6 0.1 1.9e-29 103.2 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KEZ34353.1 - 0.0054 16.7 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 KEZ34353.1 - 0.019 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH_1 PF00378.20 KEZ34354.1 - 9.1e-16 57.9 0.0 1.9e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ34354.1 - 1.9e-06 27.7 0.1 2.3e-05 24.0 0.0 2.3 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KEZ34355.1 - 1.2e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chal_sti_synt_C PF02797.15 KEZ34356.1 - 3.8e-16 59.4 0.0 1e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 KEZ34356.1 - 7.3e-13 48.5 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.19 KEZ34356.1 - 8.7e-12 44.9 1.9 1.4e-11 44.2 1.9 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KEZ34356.1 - 6.3e-10 38.8 0.1 9.5e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KEZ34356.1 - 3.6e-06 26.7 2.5 8.7e-06 25.5 2.5 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioesterase PF00975.20 KEZ34357.1 - 3.5e-32 112.4 0.0 5.2e-31 108.5 0.0 2.3 1 1 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 KEZ34357.1 - 7.3e-18 65.3 1.7 2.1e-17 63.8 1.7 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ34357.1 - 2e-16 60.1 0.1 4.4e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KEZ34357.1 - 4.2e-07 30.8 6.1 4.2e-07 30.8 6.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ34357.1 - 0.0005 19.8 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ34357.1 - 0.0012 18.1 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KEZ34357.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Condensation PF00668.20 KEZ34358.1 - 1.6e-76 257.8 0.0 2e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KEZ34358.1 - 1.9e-16 59.7 1.6 2.9e-16 59.1 1.6 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ABC_membrane PF00664.23 KEZ34359.1 - 3.9e-41 141.5 9.1 5.1e-41 141.1 9.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ34359.1 - 3.4e-33 115.1 0.0 6.1e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ34359.1 - 8.2e-08 31.9 0.1 8.9e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 KEZ34359.1 - 0.0011 18.3 11.6 0.0011 18.3 11.6 1.7 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.6 KEZ34359.1 - 0.0036 17.7 0.9 0.018 15.5 0.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ34359.1 - 0.0063 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 KEZ34359.1 - 0.0078 16.4 0.2 0.11 12.7 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KEZ34359.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEZ34359.1 - 0.018 14.3 0.0 0.053 12.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 KEZ34359.1 - 0.037 14.4 0.1 0.65 10.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2456 PF10445.9 KEZ34359.1 - 0.039 14.0 1.6 0.11 12.6 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) AAA_25 PF13481.6 KEZ34359.1 - 0.041 13.5 1.9 0.26 10.8 1.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ34359.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ34359.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ34359.1 - 0.18 11.9 0.0 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KEZ34359.1 - 0.23 11.7 0.5 1.5 9.1 0.5 2.2 1 1 0 1 1 1 0 AAA domain FMN_dh PF01070.18 KEZ34360.1 - 3.3e-123 411.1 0.1 3.7e-123 411.0 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KEZ34360.1 - 1.3e-07 31.4 5.3 2.2e-07 30.6 5.3 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KEZ34360.1 - 3.7e-05 23.2 1.7 0.026 13.8 0.6 2.8 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KEZ34360.1 - 5.3e-05 22.5 0.1 0.051 12.7 0.0 2.1 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KEZ34360.1 - 0.00012 21.2 2.3 0.00034 19.7 2.0 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KEZ34360.1 - 0.00074 19.0 0.1 0.0091 15.5 0.1 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 KEZ34360.1 - 0.0084 15.3 0.4 0.019 14.1 0.4 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase G3P_antiterm PF04309.12 KEZ34360.1 - 0.018 14.5 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 KEZ34360.1 - 0.021 14.2 0.3 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 Thiamine monophosphate synthase DHO_dh PF01180.21 KEZ34360.1 - 0.11 11.7 0.2 0.18 10.9 0.2 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase CM_1 PF07736.11 KEZ34361.1 - 3.2e-42 143.6 0.0 3.6e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate mutase type I DUF4797 PF16051.5 KEZ34361.1 - 0.096 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) Trp_halogenase PF04820.14 KEZ34362.1 - 2.8e-90 303.4 1.1 5.5e-68 229.9 0.2 2.0 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KEZ34362.1 - 2.7e-18 66.3 0.0 3.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KEZ34362.1 - 4.5e-11 42.5 0.6 5.7e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ34362.1 - 9.9e-11 41.8 0.3 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEZ34362.1 - 1.1e-10 41.5 0.1 1.9e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ34362.1 - 1e-06 27.7 0.0 0.00012 20.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ34362.1 - 2.9e-06 26.7 0.4 0.00029 20.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ34362.1 - 6.2e-06 26.3 0.2 3.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ34362.1 - 6.6e-05 22.1 1.2 0.012 14.7 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ34362.1 - 0.00028 20.2 0.0 0.00087 18.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 KEZ34362.1 - 0.0015 17.9 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 KEZ34362.1 - 0.011 14.9 0.1 0.024 13.7 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 KEZ34362.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.27 KEZ34362.1 - 0.043 14.4 0.2 0.91 10.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ34362.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEZ34362.1 - 0.083 12.8 0.0 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ParBc PF02195.18 KEZ34363.1 - 1e-06 28.9 2.5 1.4e-06 28.5 0.1 2.5 4 0 0 4 4 4 1 ParB-like nuclease domain HTH_AsnC-type PF13404.6 KEZ34363.1 - 7.7e-06 25.6 1.5 0.0057 16.5 0.1 4.2 4 0 0 4 4 4 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 KEZ34363.1 - 1.2e-05 25.0 0.3 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_24 PF13412.6 KEZ34363.1 - 5.8e-05 22.6 0.6 0.0032 17.0 0.1 3.3 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KEZ34363.1 - 0.0049 16.6 0.1 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 KEZ34363.1 - 0.0075 16.6 3.4 8.4 6.8 0.0 3.7 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_28 PF13518.6 KEZ34363.1 - 0.025 14.7 1.7 0.12 12.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KEZ34363.1 - 0.032 14.3 0.2 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF1013 PF06242.11 KEZ34363.1 - 0.1 12.6 0.0 3.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) TetR_N PF00440.23 KEZ34363.1 - 0.11 12.3 0.1 0.35 10.7 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 KEZ34363.1 - 0.12 12.5 0.1 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Med15_fungi PF05397.12 KEZ34363.1 - 0.15 12.3 0.0 1 9.7 0.0 2.3 3 0 0 3 3 3 0 Mediator complex subunit 15 LacI PF00356.21 KEZ34363.1 - 0.15 11.8 2.4 0.2 11.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DDE_Tnp_1_assoc PF13808.6 KEZ34364.1 - 8.5e-11 41.7 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ34365.1 - 1.7e-05 24.5 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain HIT PF01230.23 KEZ34367.1 - 0.00017 22.3 0.0 0.00025 21.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DDE_Tnp_Tn3 PF01526.17 KEZ34368.1 - 1.1e-115 386.6 0.5 1.6e-115 386.0 0.5 1.2 1 0 0 1 1 1 1 Tn3 transposase DDE domain DDE_Tnp_Tn3 PF01526.17 KEZ34369.1 - 1.4e-43 149.2 0.0 1.3e-25 90.1 0.0 2.0 1 1 1 2 2 2 2 Tn3 transposase DDE domain Zip PF02535.22 KEZ34370.1 - 5e-11 42.4 16.2 9.7e-08 31.6 16.3 2.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2919 PF11143.8 KEZ34370.1 - 2.7 8.3 4.6 11 6.3 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2919) HisKA PF00512.25 KEZ34371.1 - 7.1e-12 45.2 3.5 1.5e-11 44.2 3.5 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 KEZ34371.1 - 1.4e-08 35.2 0.0 3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KEZ34371.1 - 1.1e-05 25.7 1.4 1.9e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 HAMP domain MauE PF07291.11 KEZ34371.1 - 0.38 10.5 6.3 0.057 13.2 0.9 2.0 2 0 0 2 2 2 0 Methylamine utilisation protein MauE PsbX PF06596.11 KEZ34371.1 - 1.4 9.0 11.7 2.9 7.9 2.6 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Response_reg PF00072.24 KEZ34372.1 - 2.1e-23 82.6 0.0 3e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ34372.1 - 6.9e-18 64.5 0.0 1.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal OKR_DC_1_N PF03709.15 KEZ34372.1 - 0.0098 16.2 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain FliD_C PF07195.12 KEZ34372.1 - 0.24 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF347 PF03988.12 KEZ34373.1 - 7.1e-46 154.2 48.7 8.1e-16 58.0 4.9 4.7 5 0 0 5 5 5 4 Repeat of Unknown Function (DUF347) LZ_Tnp_IS66 PF13007.7 KEZ34375.1 - 1.5e-05 25.6 0.5 1.5e-05 25.6 0.5 1.8 1 1 1 2 2 2 1 Transposase C of IS166 homeodomain HALZ PF02183.18 KEZ34375.1 - 0.16 12.2 1.1 3.1 8.1 0.3 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper rve PF00665.26 KEZ34376.1 - 8.9e-13 48.5 0.1 9.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 KEZ34376.1 - 4e-11 42.9 1.2 7.7e-11 42.0 1.2 1.5 1 0 0 1 1 1 1 HTH-like domain HTH_Tnp_Tc3_2 PF01498.18 KEZ34376.1 - 0.023 14.9 0.2 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 Transposase HTH_Tnp_1 PF01527.20 KEZ34377.1 - 4.8e-14 52.4 0.8 8.2e-14 51.7 0.8 1.3 1 1 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 KEZ34377.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KEZ34377.1 - 0.0039 17.3 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ34377.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HA PF03457.14 KEZ34377.1 - 0.016 15.5 0.1 0.023 15.0 0.1 1.5 1 1 0 1 1 1 0 Helicase associated domain DEDD_Tnp_IS110 PF01548.17 KEZ34378.1 - 3.3e-25 88.8 0.1 5.2e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 KEZ34378.1 - 3.6e-19 68.9 0.2 7e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DUF3037 PF11236.8 KEZ34380.1 - 6.7e-39 133.0 0.0 7.4e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3037) Phytoreo_S7 PF07236.11 KEZ34380.1 - 0.03 12.7 0.0 0.037 12.4 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein MFS_1 PF07690.16 KEZ34381.1 - 3.5e-47 161.0 53.6 2.3e-46 158.4 48.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KEZ34381.1 - 3.3e-07 29.1 12.2 3.3e-07 29.1 12.2 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1422 PF07226.11 KEZ34381.1 - 0.0022 18.0 0.9 0.35 10.9 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1422) TMEM100 PF16311.5 KEZ34381.1 - 1.2 8.8 6.0 0.91 9.1 0.6 2.7 2 1 1 3 3 3 0 Transmembrane protein 100 TetR_N PF00440.23 KEZ34383.1 - 2.3e-15 56.1 0.5 5.1e-15 55.0 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 KEZ34383.1 - 1.2e-07 31.9 4.7 1.2e-07 31.9 4.7 1.9 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 KEZ34383.1 - 1.4e-05 25.2 7.5 1.4e-05 25.2 7.5 2.4 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 KEZ34383.1 - 0.028 14.5 0.0 0.071 13.2 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 KEZ34383.1 - 0.073 13.0 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Acyl_transf_1 PF00698.21 KEZ34384.1 - 1.1e-76 258.5 0.4 1.4e-76 258.1 0.4 1.1 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_11 PF08241.12 KEZ34385.1 - 2.5e-21 76.1 0.0 6.2e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ34385.1 - 5.6e-20 71.9 0.0 6.8e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34385.1 - 2.8e-16 59.7 0.0 3.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34385.1 - 3.5e-12 46.5 0.0 4.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34385.1 - 5.7e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ34385.1 - 2.1e-11 43.6 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KEZ34385.1 - 9.7e-05 22.3 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KEZ34385.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KEZ34385.1 - 0.00024 22.1 0.1 0.00059 20.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KEZ34385.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KEZ34385.1 - 0.0065 16.1 0.0 0.03 14.0 0.0 1.9 1 1 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KEZ34385.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 KEZ34385.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 KEZ34385.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.17 KEZ34385.1 - 0.095 11.9 0.0 0.25 10.5 0.0 1.6 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 KEZ34385.1 - 0.23 10.9 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Asp_decarbox PF02261.16 KEZ34386.1 - 1.7e-48 163.3 0.1 2.2e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase RcpC PF16976.5 KEZ34386.1 - 0.024 14.7 0.0 8.6 6.5 0.0 2.2 1 1 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB p450 PF00067.22 KEZ34387.1 - 4.9e-22 78.3 0.1 3.7e-14 52.3 0.0 2.9 2 1 0 3 3 3 2 Cytochrome P450 PNP_UDP_1 PF01048.20 KEZ34389.1 - 8e-33 113.6 1.7 1.3e-32 113.0 1.7 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily NUDIX PF00293.28 KEZ34390.1 - 1.5e-12 47.7 0.0 2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DoxX_2 PF13564.6 KEZ34391.1 - 0.071 13.2 1.2 0.1 12.7 1.2 1.3 1 0 0 1 1 1 0 DoxX-like family Type_ISP_C PF18135.1 KEZ34392.1 - 6.9e-60 202.8 0.0 9.8e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Type ISP C-terminal specificity domain N6_Mtase PF02384.16 KEZ34392.1 - 9.3e-13 48.1 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Eco57I PF07669.11 KEZ34392.1 - 0.017 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase DDE_Tnp_IS66 PF03050.14 KEZ34393.1 - 3.5e-44 151.4 0.1 4.1e-44 151.2 0.1 1.0 1 0 0 1 1 1 1 Transposase IS66 family rve_3 PF13683.6 KEZ34394.1 - 5.9e-08 32.4 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Acyl-CoA_dh_2 PF08028.11 KEZ34395.1 - 3.8e-18 66.1 9.1 8.2e-18 65.0 9.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ34395.1 - 9.2e-06 26.3 0.1 2.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KEZ34395.1 - 0.0012 19.1 1.2 0.0022 18.2 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LMWPc PF01451.21 KEZ34396.1 - 1.1e-15 58.2 0.0 2.9e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MOSC PF03473.17 KEZ34397.1 - 0.018 15.0 0.0 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 MOSC domain GvpL_GvpF PF06386.11 KEZ34398.1 - 6.8e-48 163.7 0.0 8.2e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF Gas_vesicle PF00741.18 KEZ34399.1 - 3.5e-11 43.1 9.6 5e-11 42.6 9.6 1.2 1 0 0 1 1 1 1 Gas vesicle protein GvpL_GvpF PF06386.11 KEZ34400.1 - 6.7e-14 52.4 2.5 1.5e-11 44.7 0.0 3.0 2 1 1 3 3 3 3 Gas vesicle synthesis protein GvpL/GvpF WT1 PF02165.15 KEZ34401.1 - 0.079 12.2 0.6 0.09 12.0 0.6 1.1 1 0 0 1 1 1 0 Wilm's tumour protein EAL PF00563.20 KEZ34402.1 - 3.3e-63 213.4 0.0 5.4e-63 212.7 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KEZ34402.1 - 4.7e-41 140.2 0.0 7.9e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 KEZ34402.1 - 6.9e-15 55.2 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KEZ34402.1 - 6.7e-14 52.1 1.0 2.9e-13 50.0 0.1 2.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KEZ34402.1 - 2.2e-11 43.8 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KEZ34402.1 - 8.3e-11 41.7 0.2 7.5e-10 38.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KEZ34402.1 - 1.3e-09 38.2 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold Methyltransf_19 PF04672.12 KEZ34403.1 - 9.4e-90 300.7 0.5 1.1e-89 300.5 0.5 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_12 PF08242.12 KEZ34403.1 - 0.00014 22.6 0.0 0.00022 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34403.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ34403.1 - 0.097 13.3 0.0 0.93 10.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ34403.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Flavodoxin_3 PF12641.7 KEZ34404.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_1 PF00258.25 KEZ34404.1 - 0.029 14.6 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin Condensation PF00668.20 KEZ34405.1 - 5.9e-28 97.8 0.0 8.7e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KEZ34405.1 - 1.1e-13 51.9 0.0 2.8e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ34405.1 - 3.4e-13 49.7 0.0 1e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KEZ34405.1 - 1.5e-11 43.6 0.0 2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_6 PF12697.7 KEZ34406.1 - 1.6e-22 81.2 4.7 1.9e-22 81.0 4.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ34406.1 - 2.3e-21 76.6 0.0 2.3e-14 53.7 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ34406.1 - 2e-11 43.6 0.0 2.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FtsX PF02687.21 KEZ34407.1 - 1.7e-11 44.4 2.1 1.7e-11 44.4 2.1 3.2 2 1 1 3 3 3 1 FtsX-like permease family ABC_tran PF00005.27 KEZ34408.1 - 7.3e-33 114.0 0.0 9.4e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ34408.1 - 5.8e-06 26.3 0.1 0.083 12.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ34408.1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ34408.1 - 0.007 16.6 0.5 0.062 13.6 0.5 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEZ34408.1 - 0.0085 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 KEZ34408.1 - 0.0089 15.5 0.0 0.17 11.3 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KEZ34408.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 KEZ34408.1 - 0.068 13.1 1.3 0.14 12.1 0.4 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KEZ34408.1 - 0.082 13.3 1.2 0.13 12.6 1.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ34408.1 - 0.12 12.4 0.1 0.32 11.1 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 KEZ34408.1 - 0.14 11.4 0.2 0.24 10.5 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KEZ34408.1 - 0.19 12.2 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MacB_PCD PF12704.7 KEZ34409.1 - 4.4e-16 59.8 8.5 1.2e-15 58.4 8.5 1.8 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 KEZ34409.1 - 3.2e-12 46.8 2.6 3.2e-12 46.8 2.6 3.2 3 0 0 3 3 3 1 FtsX-like permease family zf-C2H2_6 PF13912.6 KEZ34409.1 - 0.021 14.8 0.5 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger HATPase_c PF02518.26 KEZ34410.1 - 2.8e-14 53.6 0.0 4.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ34410.1 - 4.1e-12 46.0 0.5 1.9e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ34410.1 - 5.3e-10 39.5 1.2 1.6e-09 38.0 1.2 1.9 1 0 0 1 1 1 1 HAMP domain Rx_N PF18052.1 KEZ34410.1 - 0.033 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Rx N-terminal domain HATPase_c_5 PF14501.6 KEZ34410.1 - 0.21 11.5 0.0 0.84 9.6 0.0 1.9 1 1 0 1 1 1 0 GHKL domain Neurensin PF14927.6 KEZ34410.1 - 4.1 7.1 4.5 3.4 7.4 0.5 2.2 1 1 1 2 2 2 0 Neurensin Response_reg PF00072.24 KEZ34411.1 - 2.1e-21 76.2 0.1 2.8e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ34411.1 - 1.4e-20 73.1 0.0 2.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal LZ_Tnp_IS66 PF13007.7 KEZ34413.1 - 7.9e-06 26.6 0.6 1.6e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Transposase C of IS166 homeodomain HATPase_c_2 PF13581.6 KEZ34414.1 - 3.9e-07 30.0 0.1 4.7e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ34414.1 - 0.047 14.2 0.0 0.062 13.8 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT PF02985.22 KEZ34414.1 - 0.058 13.7 0.6 18 5.9 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat HTH_31 PF13560.6 KEZ34415.1 - 2.1e-15 56.8 6.0 7.1e-15 55.1 6.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34415.1 - 5.9e-05 23.0 0.2 0.00012 22.1 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ34415.1 - 0.0003 20.8 0.1 0.00047 20.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KEZ34415.1 - 0.008 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ34415.1 - 0.0084 15.9 1.7 0.021 14.7 1.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain N_formyltrans_C PF18216.1 KEZ34415.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain DUF397 PF04149.12 KEZ34416.1 - 5.9e-22 77.5 0.1 7.3e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Beta-lactamase PF00144.24 KEZ34417.1 - 7.7e-35 120.7 1.6 1.1e-34 120.2 1.6 1.2 1 0 0 1 1 1 1 Beta-lactamase Tecti-min-caps PF09300.10 KEZ34417.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 Tectiviridae, minor capsid Pkinase PF00069.25 KEZ34420.1 - 4.2e-19 69.0 0.0 7.4e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ34420.1 - 2.9e-13 49.7 0.0 5.2e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ34420.1 - 1.4e-05 24.1 0.0 1.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEZ34420.1 - 1.9e-05 24.2 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEZ34420.1 - 0.0017 17.7 0.0 0.0052 16.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ34420.1 - 0.08 12.8 5.7 0.029 14.3 1.5 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Thymidylate_kin PF02223.17 KEZ34421.1 - 7.6e-10 38.8 0.0 1.1e-05 25.3 0.0 2.0 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 KEZ34421.1 - 0.00065 19.9 0.1 0.0013 18.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KEZ34421.1 - 0.015 15.2 0.0 2.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 KEZ34421.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KEZ34421.1 - 0.11 12.8 0.0 0.48 10.7 0.0 1.9 1 1 0 2 2 2 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 KEZ34422.1 - 3.2e-06 27.9 0.0 7.3e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ORF_12_N PF18042.1 KEZ34422.1 - 0.095 13.1 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 ORF 12 gene product N-terminal Radical_SAM PF04055.21 KEZ34424.1 - 9.4e-11 42.4 0.0 1.9e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ34424.1 - 0.0004 20.7 0.0 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ34424.1 - 0.00049 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain NUDIX PF00293.28 KEZ34425.1 - 5.9e-16 58.7 0.6 7.4e-16 58.4 0.6 1.0 1 0 0 1 1 1 1 NUDIX domain DUF4096 PF13340.6 KEZ34426.1 - 8.1e-27 93.3 0.1 9.1e-27 93.1 0.1 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DUF4287 PF14117.6 KEZ34428.1 - 1.6 8.9 4.3 1.3 9.2 0.1 2.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4287) UBA_5 PF16577.5 KEZ34429.1 - 0.11 12.7 0.4 0.22 11.7 0.2 1.7 1 1 1 2 2 2 0 UBA domain TPR_11 PF13414.6 KEZ34430.1 - 0.13 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 TPR repeat AAA PF00004.29 KEZ34431.1 - 1e-14 55.1 0.0 1.2e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEZ34431.1 - 2.6e-07 30.7 0.0 3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ34431.1 - 0.00036 20.8 0.0 0.015 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ34431.1 - 0.00071 20.0 0.2 0.0043 17.5 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 KEZ34431.1 - 0.0013 18.7 0.2 0.021 14.7 0.1 2.0 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.6 KEZ34431.1 - 0.0021 18.6 0.0 0.0021 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KEZ34431.1 - 0.0029 17.7 0.0 0.0065 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KEZ34431.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.4 1 1 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KEZ34431.1 - 0.012 15.3 0.1 0.022 14.5 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KEZ34431.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ34431.1 - 0.019 15.1 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ34431.1 - 0.034 14.1 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KEZ34431.1 - 0.044 13.8 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEZ34431.1 - 0.048 14.1 0.1 0.062 13.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KEZ34431.1 - 0.074 12.8 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KEZ34431.1 - 0.076 13.4 0.0 0.087 13.2 0.0 1.3 1 1 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KEZ34431.1 - 0.09 12.0 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KEZ34431.1 - 0.16 12.0 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pirin PF02678.16 KEZ34432.1 - 5.1e-30 103.6 0.3 1.2e-29 102.5 0.3 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KEZ34432.1 - 2.2e-29 101.9 0.0 8e-29 100.1 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_1 PF00190.22 KEZ34432.1 - 0.00055 19.6 0.2 0.0015 18.1 0.2 1.8 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KEZ34432.1 - 0.0069 16.1 2.0 3.8 7.3 0.0 2.9 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KEZ34432.1 - 0.13 12.0 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) NicO PF03824.16 KEZ34433.1 - 4.4e-87 292.0 12.5 4.4e-87 292.0 12.5 1.8 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF3367 PF11847.8 KEZ34434.1 - 2.8e-94 316.3 11.5 2.8e-94 316.3 11.5 2.0 2 0 0 2 2 2 1 Alpha-(1->3)-arabinofuranosyltransferase F5_F8_type_C PF00754.25 KEZ34434.1 - 3.5e-10 40.1 0.8 0.0012 19.0 0.3 2.4 2 0 0 2 2 2 2 F5/8 type C domain DUF4381 PF14316.6 KEZ34434.1 - 0.2 11.9 1.3 1.8 8.8 1.3 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Collagen PF01391.18 KEZ34434.1 - 8.2 6.3 19.4 0.049 13.4 8.7 2.6 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Glycos_transf_1 PF00534.20 KEZ34435.1 - 1.1e-28 99.9 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ34435.1 - 1.1e-22 80.9 0.1 2.4e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ34435.1 - 1.5e-11 44.5 0.2 1.1e-10 41.8 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ34435.1 - 1.6e-11 44.5 2.5 1.9e-11 44.3 0.5 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Polysacc_synt PF01943.17 KEZ34436.1 - 0.0026 17.2 9.2 0.012 15.0 9.2 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GIIM PF08388.11 KEZ34438.1 - 4.2e-17 62.0 5.3 7e-17 61.3 5.3 1.3 1 0 0 1 1 1 1 Group II intron, maturase-specific domain RVT_1 PF00078.27 KEZ34438.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) PhdYeFM_antitox PF02604.19 KEZ34440.1 - 2.1e-15 56.2 0.1 2.6e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 KEZ34440.1 - 0.13 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system YoeB_toxin PF06769.14 KEZ34441.1 - 1.6e-35 121.0 0.4 1.8e-35 120.8 0.4 1.0 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system ParE_toxin PF05016.15 KEZ34441.1 - 0.00039 21.0 0.1 0.0005 20.6 0.1 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Gp49 PF05973.14 KEZ34441.1 - 0.071 13.3 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) HTH_18 PF12833.7 KEZ34443.1 - 1.3e-22 79.9 0.3 2e-22 79.2 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KEZ34443.1 - 4.9e-15 55.2 0.0 1.6e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 KEZ34443.1 - 0.041 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family RHH_1 PF01402.21 KEZ34443.1 - 0.074 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family DJ-1_PfpI PF01965.24 KEZ34445.1 - 1.8e-19 70.1 0.1 2.4e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2069 PF09842.9 KEZ34445.1 - 0.019 15.2 0.1 0.024 14.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF2867 PF11066.8 KEZ34446.1 - 2.7e-29 102.4 0.1 3.3e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) Big_3_4 PF13754.6 KEZ34446.1 - 0.24 11.2 0.0 0.57 9.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function Flavodoxin_2 PF02525.17 KEZ34448.1 - 5.4e-56 189.4 0.0 6.5e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KEZ34448.1 - 2.7e-09 36.9 0.0 4.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase MLTR_LBD PF17765.1 KEZ34449.1 - 8.2e-42 143.2 2.0 1.6e-41 142.3 2.0 1.5 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KEZ34449.1 - 4.5e-15 55.7 2.7 4.5e-15 55.7 2.7 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34449.1 - 4.2e-06 26.7 0.0 9.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix MR_MLE_C PF13378.6 KEZ34450.1 - 0.052 13.1 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like Hydrolase_4 PF12146.8 KEZ34450.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PIN PF01850.21 KEZ34451.1 - 4.7e-10 40.0 0.0 6.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 PIN domain Antigen_Bd37 PF11641.8 KEZ34451.1 - 0.21 11.1 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein MazE_antitoxin PF04014.18 KEZ34452.1 - 0.00014 21.7 0.3 0.00062 19.6 0.1 2.1 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin PhyH PF05721.13 KEZ34453.1 - 3.7e-08 33.9 0.0 6.2e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Abhydrolase_3 PF07859.13 KEZ34454.1 - 2.3e-12 47.2 0.0 2.8e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold T4SS_TraI PF16932.5 KEZ34455.1 - 0.078 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer DUF4730 PF15873.5 KEZ34458.1 - 0.015 15.5 0.4 0.017 15.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) Zn_ribbon_recom PF13408.6 KEZ34459.1 - 0.022 15.3 0.7 0.037 14.5 0.7 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF4224 PF13986.6 KEZ34459.1 - 0.045 13.6 0.2 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) DUF4862 PF16154.5 KEZ34459.1 - 0.076 12.4 0.1 6.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4862) Zn_ribbon_recom PF13408.6 KEZ34460.1 - 1.8e-05 25.1 1.2 3.1e-05 24.4 1.2 1.4 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain CdvA PF18822.1 KEZ34460.1 - 0.097 12.5 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain zf-RRN7 PF11781.8 KEZ34460.1 - 0.35 10.6 0.1 0.35 10.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sigma70_r4_2 PF08281.12 KEZ34461.1 - 0.017 14.8 1.3 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_36 PF13730.6 KEZ34461.1 - 0.2 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain AP_endonuc_2 PF01261.24 KEZ34462.1 - 6.5e-25 87.8 0.0 8.6e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Acetyltransf_CG PF14542.6 KEZ34462.1 - 0.016 15.3 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GFO_IDH_MocA PF01408.22 KEZ34463.1 - 7.6e-12 46.1 0.0 1.6e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KEZ34463.1 - 0.085 13.4 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain ThiF PF00899.21 KEZ34463.1 - 0.23 10.8 0.2 0.44 9.9 0.2 1.5 1 0 0 1 1 1 0 ThiF family AdoMet_Synthase PF01941.19 KEZ34464.1 - 3.9e-67 226.8 0.0 5.3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) Hpr_kinase_C PF07475.12 KEZ34465.1 - 0.0003 20.4 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 KEZ34465.1 - 0.034 14.7 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KEZ34465.1 - 0.052 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain TruB_C PF09142.11 KEZ34465.1 - 0.088 12.6 0.6 0.088 12.6 0.6 2.5 2 1 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal AAA_16 PF13191.6 KEZ34465.1 - 0.12 12.8 0.1 0.19 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEZ34465.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glycos_transf_2 PF00535.26 KEZ34466.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 UL42 PF17638.2 KEZ34466.1 - 0.038 14.0 0.8 0.11 12.4 0.8 1.8 1 0 0 1 1 1 0 HCMV UL42 DUF4350 PF14258.6 KEZ34466.1 - 0.31 11.5 2.2 2.3 8.7 2.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4350) F420_ligase PF01996.16 KEZ34467.1 - 4.7e-41 140.7 0.1 6.2e-41 140.3 0.1 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Epimerase PF01370.21 KEZ34468.1 - 1.4e-19 70.6 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ34468.1 - 3.5e-12 45.9 0.0 8.3e-12 44.7 0.0 1.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ34468.1 - 5.2e-12 45.8 0.2 3.1e-11 43.3 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KEZ34468.1 - 1.3e-11 44.7 0.3 1.6e-11 44.4 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEZ34468.1 - 2.2e-07 30.3 0.2 9.8e-05 21.6 0.1 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEZ34468.1 - 4.9e-06 25.8 0.1 6.5e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEZ34468.1 - 8.9e-05 21.8 4.9 0.0006 19.1 0.7 2.9 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 KEZ34468.1 - 0.00029 20.8 0.9 0.39 10.6 0.1 2.4 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 KEZ34468.1 - 0.0017 17.8 0.5 0.0079 15.7 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KEZ34468.1 - 0.015 14.8 0.1 0.049 13.2 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family adh_short_C2 PF13561.6 KEZ34468.1 - 0.093 12.3 0.7 0.24 10.9 0.7 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF397 PF04149.12 KEZ34469.1 - 1.3e-19 69.9 0.1 1.5e-19 69.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KEZ34470.1 - 2.8e-10 40.4 5.2 2.8e-10 40.4 5.2 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34470.1 - 0.00043 20.3 0.1 0.0012 18.9 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 KEZ34470.1 - 0.018 14.9 0.2 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_25 PF13413.6 KEZ34470.1 - 0.16 11.8 2.0 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HATPase_c_2 PF13581.6 KEZ34472.1 - 2e-09 37.4 0.0 3.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ34472.1 - 0.23 12.0 0.0 0.39 11.2 0.0 1.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2939 PF11159.8 KEZ34473.1 - 0.032 14.6 0.4 0.063 13.7 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) DDE_Tnp_1_2 PF13586.6 KEZ34476.1 - 2e-11 44.1 1.2 4.5e-11 43.0 1.2 1.6 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ34476.1 - 1.3e-10 41.3 2.3 8.4e-10 38.7 2.3 1.9 1 1 0 1 1 1 1 Transposase DDE domain DUF1794 PF08768.11 KEZ34477.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) POR_N PF01855.19 KEZ34478.1 - 1.7e-77 260.3 0.7 2.6e-77 259.6 0.7 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KEZ34478.1 - 6.4e-23 81.7 0.0 1.1e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 KEZ34478.1 - 7e-20 70.6 0.0 1.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function PFOR_II PF17147.4 KEZ34478.1 - 1e-12 48.2 0.3 2.5e-12 47.0 0.3 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_16 PF13484.6 KEZ34478.1 - 1.5e-10 41.9 5.0 2.9e-10 40.9 5.0 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 KEZ34478.1 - 1.5e-10 40.4 24.3 1.2e-06 28.0 3.8 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain TPP_enzyme_C PF02775.21 KEZ34478.1 - 1.2e-09 38.2 0.3 3.9e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_6 PF12837.7 KEZ34478.1 - 1.3e-09 37.7 21.5 5.1e-07 29.5 3.4 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ34478.1 - 1.4e-09 38.4 5.9 3.4e-09 37.2 5.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KEZ34478.1 - 1.2e-08 34.9 8.1 5.5e-08 32.8 8.1 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KEZ34478.1 - 1.3e-07 31.3 17.6 0.00033 20.6 4.2 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KEZ34478.1 - 3.5e-07 30.2 22.6 5.1e-06 26.5 12.4 2.4 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ34478.1 - 4.3e-07 30.0 10.3 0.0022 18.1 0.2 2.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ34478.1 - 9.5e-07 29.2 3.7 2.2e-06 28.0 3.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ34478.1 - 0.00063 20.2 8.8 0.00063 20.2 8.8 2.3 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEZ34478.1 - 0.0011 19.3 17.4 0.0099 16.3 0.8 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Transketolase_C PF02780.20 KEZ34478.1 - 0.003 17.4 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Fer4_18 PF13746.6 KEZ34478.1 - 0.027 14.7 4.6 0.044 14.0 3.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KEZ34478.1 - 0.093 13.5 8.3 0.16 12.7 0.5 3.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 KEZ34478.1 - 0.46 11.4 10.5 1.6 9.6 1.4 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KEZ34478.1 - 0.54 10.8 14.4 1.2 9.8 2.5 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KEZ34478.1 - 0.67 11.0 16.9 0.26 12.3 4.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_31 PF13614.6 KEZ34479.1 - 3.4e-34 118.3 0.0 5.3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ34479.1 - 2.1e-17 63.4 0.0 3.5e-17 62.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KEZ34479.1 - 1.8e-14 53.8 0.0 3.8e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ ParA PF10609.9 KEZ34479.1 - 3.7e-08 33.1 0.2 1e-06 28.4 0.1 2.5 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 KEZ34479.1 - 5.1e-08 32.5 0.0 1.2e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KEZ34479.1 - 4.7e-07 29.4 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 ATPase MipZ Fer4_NifH PF00142.18 KEZ34479.1 - 4.3e-06 26.4 0.0 5.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 KEZ34479.1 - 9.9e-05 21.7 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 VirC1 protein CLP1_P PF16575.5 KEZ34479.1 - 0.0054 16.5 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 KEZ34479.1 - 0.007 16.2 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KEZ34479.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KEZ34479.1 - 0.03 13.9 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Lant_dehydr_C PF14028.6 KEZ34481.1 - 1.3e-36 126.7 5.3 1.8e-36 126.3 5.3 1.1 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term LANC_like PF05147.13 KEZ34482.1 - 1.2e-39 135.9 0.0 1.9e-39 135.3 0.0 1.3 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Lant_dehydr_N PF04738.13 KEZ34483.1 - 1.1e-193 644.9 27.3 1.6e-193 644.4 27.3 1.3 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus Lant_dehydr_C PF14028.6 KEZ34483.1 - 2.5e-34 119.2 7.6 8.8e-34 117.4 7.6 2.0 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term PCMT PF01135.19 KEZ34485.1 - 2e-29 102.8 0.0 3e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEZ34485.1 - 1.3e-07 31.5 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ34485.1 - 2.2e-06 28.3 0.0 5.7e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ34485.1 - 0.00054 19.4 0.0 0.00075 18.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KEZ34485.1 - 0.0043 17.7 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34485.1 - 0.15 12.9 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KEZ34485.1 - 0.23 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DDE_Tnp_IS66 PF03050.14 KEZ34486.1 - 1e-06 28.5 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 KEZ34486.1 - 0.023 14.9 0.1 0.044 14.0 0.1 1.5 1 1 0 1 1 1 0 IS66 C-terminal element Replic_Relax PF13814.6 KEZ34487.1 - 4.1e-35 121.6 0.6 6.2e-35 121.0 0.6 1.2 1 0 0 1 1 1 1 Replication-relaxation F420H2_quin_red PF04075.14 KEZ34489.1 - 2.3e-27 95.7 0.1 2.6e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase FAD_binding_3 PF01494.19 KEZ34490.1 - 1e-84 284.8 0.0 1.2e-84 284.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ34490.1 - 2e-07 30.9 0.5 0.002 17.8 0.1 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ34490.1 - 6.9e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ34490.1 - 0.00062 20.0 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ34490.1 - 0.0009 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEZ34490.1 - 0.0017 17.7 0.0 0.0047 16.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ34490.1 - 0.026 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KEZ34490.1 - 0.041 13.1 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEZ34490.1 - 0.05 12.3 0.2 0.14 10.9 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KEZ34490.1 - 0.22 11.5 2.9 17 5.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KEZ34490.1 - 0.27 10.3 0.0 6.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Methyltransf_11 PF08241.12 KEZ34491.1 - 1.7e-24 86.3 0.0 2.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ34491.1 - 5.9e-22 78.2 0.0 9.5e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34491.1 - 2.4e-16 60.0 0.0 3.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34491.1 - 7.8e-16 58.2 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34491.1 - 6.3e-15 55.7 0.0 9.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ34491.1 - 6.2e-12 45.4 0.0 8.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ34491.1 - 1.3e-07 31.3 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ34491.1 - 8e-05 22.0 0.1 0.00013 21.3 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 KEZ34491.1 - 0.00028 20.8 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KEZ34491.1 - 0.0072 16.3 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KEZ34491.1 - 0.0091 14.6 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 KEZ34491.1 - 0.016 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KEZ34491.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KEZ34491.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.11 KEZ34491.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) ChaB PF06150.12 KEZ34491.1 - 0.026 15.1 0.7 0.04 14.5 0.1 1.6 2 0 0 2 2 1 0 ChaB CMAS PF02353.20 KEZ34491.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KEZ34491.1 - 0.05 13.0 0.1 0.066 12.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KEZ34491.1 - 0.057 13.0 0.0 0.089 12.4 0.0 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 KEZ34491.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme p450 PF00067.22 KEZ34492.1 - 6.8e-71 239.4 0.0 8.4e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 KEZ34493.1 - 1.3e-11 44.6 25.8 5.6e-05 23.3 0.3 6.3 3 3 3 6 6 6 4 Tetratricopeptide repeat HTH_19 PF12844.7 KEZ34493.1 - 3.3e-09 36.6 0.0 1.1e-08 35.0 0.0 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_31 PF13560.6 KEZ34493.1 - 4.3e-09 36.6 0.5 4.3e-09 36.6 0.5 3.9 3 1 0 3 3 3 1 Helix-turn-helix domain TPR_2 PF07719.17 KEZ34493.1 - 1.1e-07 31.4 16.5 0.31 11.3 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ34493.1 - 1.9e-07 31.6 31.7 0.00015 22.4 1.0 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ34493.1 - 1.2e-06 28.1 0.1 0.004 16.9 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat HTH_3 PF01381.22 KEZ34493.1 - 1.5e-06 28.2 0.0 4.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix TPR_14 PF13428.6 KEZ34493.1 - 9e-06 26.1 39.0 1.5 9.8 0.0 9.1 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ34493.1 - 0.00025 21.5 21.0 0.2 12.2 0.5 6.5 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ34493.1 - 0.0013 18.8 1.6 0.34 11.2 0.0 4.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ34493.1 - 0.0014 18.8 1.0 20 5.9 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ34493.1 - 0.0016 18.8 54.5 0.39 11.5 3.4 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ34493.1 - 0.0052 16.7 6.0 3.6 7.8 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ34493.1 - 0.047 13.4 1.2 0.55 10.0 0.0 3.2 3 1 1 4 4 4 0 TPR repeat Sel1 PF08238.12 KEZ34493.1 - 0.053 14.2 0.9 0.75 10.6 0.0 3.0 3 0 0 3 3 2 0 Sel1 repeat HTH_26 PF13443.6 KEZ34493.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain ANAPC3 PF12895.7 KEZ34493.1 - 0.13 12.5 0.6 15 5.9 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KEZ34493.1 - 0.42 11.4 12.0 3.2 8.6 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 KEZ34493.1 - 0.6 9.8 4.1 2.3 7.9 0.0 3.1 2 2 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KEZ34493.1 - 1.3 9.0 0.0 1.3 9.0 0.0 6.8 8 1 1 9 9 8 0 Tetratricopeptide repeat MbtH PF03621.13 KEZ34494.1 - 6.1e-22 76.8 0.1 7.8e-22 76.5 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein Methyltransf_3 PF01596.17 KEZ34495.1 - 8.5e-68 227.7 0.0 9.9e-68 227.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KEZ34495.1 - 1.3e-14 55.1 0.1 2.1e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ34495.1 - 0.00023 21.8 0.0 0.00044 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ34495.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF5612 PF18462.1 KEZ34496.1 - 0.14 11.9 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) AMP-binding PF00501.28 KEZ34497.1 - 3.3e-103 345.5 0.0 4.9e-103 345.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KEZ34497.1 - 6.6e-66 222.1 0.0 1.2e-65 221.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KEZ34497.1 - 1.3e-58 198.8 0.0 1.8e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KEZ34497.1 - 4.9e-17 62.7 0.0 2.1e-16 60.7 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ34497.1 - 2e-12 47.3 0.1 9e-12 45.2 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KEZ34497.1 - 3.2e-08 32.9 0.0 6.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ34497.1 - 4.4e-08 32.9 0.0 8.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ34497.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEZ34497.1 - 0.0075 16.2 0.0 0.084 12.8 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEZ34497.1 - 0.15 11.9 0.1 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 KEZ34497.1 - 0.2 11.0 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 KEZ34498.1 - 5.6e-13 49.0 0.3 1.1e-12 48.1 0.2 1.5 1 1 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ34498.1 - 2.7e-08 34.7 0.0 1.1e-07 32.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DDE_Tnp_IS66 PF03050.14 KEZ34499.1 - 7.1e-07 29.0 0.0 8.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 KEZ34499.1 - 0.0061 16.8 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 IS66 C-terminal element Ser_hydrolase PF06821.13 KEZ34501.1 - 3e-50 170.4 0.0 3.5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 KEZ34501.1 - 1.9e-06 28.6 9.1 2.8e-06 28.1 9.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ34501.1 - 2.7e-05 23.9 0.0 0.0004 20.1 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ34501.1 - 0.0011 18.3 0.0 0.0079 15.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3748 PF12566.8 KEZ34501.1 - 0.065 13.2 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Abhydrolase_4 PF08386.10 KEZ34501.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Trp_halogenase PF04820.14 KEZ34502.1 - 7.2e-11 41.6 0.1 9.3e-11 41.2 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KEZ34502.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain AMP-binding PF00501.28 KEZ34503.1 - 2e-11 43.1 0.0 2.4e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_3 PF01757.22 KEZ34504.1 - 1.7e-16 60.3 24.8 3.2e-16 59.3 24.8 1.4 1 1 0 1 1 1 1 Acyltransferase family HTH_33 PF13592.6 KEZ34505.1 - 0.067 12.8 0.2 0.084 12.5 0.2 1.2 1 0 0 1 1 1 0 Winged helix-turn helix PemK_toxin PF02452.17 KEZ34506.1 - 1.6e-19 70.3 0.0 1.7e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF4177 PF13783.6 KEZ34507.1 - 0.081 13.2 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4177) Arc PF03869.14 KEZ34508.1 - 0.00062 19.6 0.2 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 Arc-like DNA binding domain HicB PF05534.12 KEZ34508.1 - 0.18 11.7 0.4 0.18 11.7 0.4 1.6 2 0 0 2 2 2 0 HicB family Abhydrolase_1 PF00561.20 KEZ34510.1 - 5.2e-33 114.8 0.0 1.9e-32 113.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KEZ34510.1 - 5e-25 87.6 0.1 4.8e-24 84.4 0.0 2.5 3 0 0 3 3 3 1 TAP-like protein Hydrolase_4 PF12146.8 KEZ34510.1 - 0.0025 17.1 0.1 2 7.6 0.0 3.3 3 1 0 3 3 3 2 Serine aminopeptidase, S33 Glyoxalase PF00903.25 KEZ34511.1 - 5.8e-09 36.2 0.0 7.9e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ34511.1 - 0.00023 21.4 0.0 0.0015 18.8 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEZ34511.1 - 0.0022 18.8 0.1 0.0036 18.1 0.1 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain PaaX PF07848.12 KEZ34511.1 - 0.13 12.5 0.1 0.24 11.6 0.0 1.5 2 0 0 2 2 2 0 PaaX-like protein MIP PF00230.20 KEZ34512.1 - 2.1e-23 83.2 15.1 2.7e-20 73.1 10.0 2.0 1 1 1 2 2 2 2 Major intrinsic protein LMWPc PF01451.21 KEZ34513.1 - 4.9e-20 72.4 0.0 7.2e-20 71.8 0.0 1.3 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CRCB PF02537.15 KEZ34514.1 - 2.3e-20 72.7 9.7 3.2e-20 72.2 9.7 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF805 PF05656.14 KEZ34514.1 - 0.34 11.3 3.4 0.53 10.7 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF190 PF02641.15 KEZ34515.1 - 2.4e-38 130.3 0.1 2.8e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 CRCB PF02537.15 KEZ34516.1 - 5e-23 81.2 6.6 6.2e-23 80.9 6.6 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Methyltransf_14 PF08484.11 KEZ34516.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain MFS_1 PF07690.16 KEZ34517.1 - 8.3e-17 61.1 48.5 5.6e-12 45.2 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 KEZ34521.1 - 5.6e-41 140.5 0.0 7.5e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PknH_C PF14032.6 KEZ34521.1 - 0.074 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 PknH-like extracellular domain DEDD_Tnp_IS110 PF01548.17 KEZ34522.1 - 2.2e-18 66.6 0.0 3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Transposase Peripla_BP_3 PF13377.6 KEZ34523.1 - 4.6e-24 85.6 0.6 4.9e-24 85.5 0.6 1.0 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 KEZ34523.1 - 0.0002 21.0 0.0 0.00043 20.0 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KEZ34523.1 - 0.0092 15.4 0.0 0.0094 15.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family adh_short_C2 PF13561.6 KEZ34524.1 - 4.1e-59 200.0 0.6 5.1e-59 199.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ34524.1 - 1e-39 136.0 1.2 1.3e-39 135.7 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ34524.1 - 1.1e-05 25.4 1.1 1.6e-05 24.9 1.1 1.1 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KEZ34525.1 - 1.4e-12 48.1 0.0 3.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ34525.1 - 1.6e-11 44.7 0.0 3.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34525.1 - 1.1e-10 41.6 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34525.1 - 2e-09 38.1 0.0 4.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEZ34525.1 - 7.9e-07 28.6 0.1 9.5e-05 21.8 0.0 2.5 1 1 1 2 2 2 1 O-methyltransferase domain NodS PF05401.11 KEZ34525.1 - 7.2e-06 25.8 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KEZ34525.1 - 4e-05 23.2 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KEZ34525.1 - 0.00013 21.4 0.0 0.00037 19.9 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KEZ34525.1 - 0.00066 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_31 PF13847.6 KEZ34525.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ34525.1 - 0.0026 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KEZ34525.1 - 0.037 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB TOBE PF03459.17 KEZ34525.1 - 0.13 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 TOBE domain RrnaAD PF00398.20 KEZ34525.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DXP_reductoisom PF02670.16 KEZ34527.1 - 0.076 13.7 0.0 0.083 13.6 0.0 1.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Inositol_P PF00459.25 KEZ34529.1 - 7.3e-08 32.2 0.1 8.3e-08 32.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Inositol_P PF00459.25 KEZ34530.1 - 4e-06 26.6 0.1 5.1e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 KEZ34530.1 - 0.0022 17.5 0.1 0.0028 17.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain BPD_transp_1 PF00528.22 KEZ34531.1 - 9.7e-08 32.0 0.5 9.7e-08 32.0 0.5 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Amidohydro_1 PF01979.20 KEZ34531.1 - 0.00031 20.2 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family ABC_tran PF00005.27 KEZ34532.1 - 4.3e-32 111.5 0.0 5.9e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ34532.1 - 1.3e-06 28.5 0.4 0.024 14.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ34532.1 - 9.7e-05 22.2 0.1 0.00023 21.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ34532.1 - 0.00073 20.0 3.0 0.002 18.5 2.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KEZ34532.1 - 0.0011 19.1 0.0 0.0018 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEZ34532.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ34532.1 - 0.0018 18.2 0.2 0.0038 17.2 0.1 1.5 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 KEZ34532.1 - 0.0024 18.1 0.1 0.12 12.7 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KEZ34532.1 - 0.0039 16.7 0.1 0.32 10.4 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ34532.1 - 0.061 13.6 0.4 0.21 11.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ34532.1 - 0.066 13.1 0.5 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KEZ34532.1 - 0.095 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 KEZ34532.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 KEZ34532.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEZ34532.1 - 0.12 12.0 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KEZ34532.1 - 0.19 10.4 0.0 0.84 8.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEZ34532.1 - 0.24 11.3 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Phosphonate-bd PF12974.7 KEZ34533.1 - 2.2e-56 191.2 0.0 2.7e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KEZ34533.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KEZ34533.1 - 3.7e-05 23.3 0.0 0.00033 20.2 0.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Acetate_kinase PF00871.17 KEZ34533.1 - 0.14 10.8 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Acetokinase family MinE PF03776.14 KEZ34533.1 - 0.18 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE HATPase_c PF02518.26 KEZ34534.1 - 2.5e-18 66.6 0.0 4.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ34534.1 - 6.3e-15 55.0 0.0 1.4e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KEZ34534.1 - 0.00053 20.0 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain MscS_porin PF12795.7 KEZ34534.1 - 0.0074 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain HATPase_c_5 PF14501.6 KEZ34534.1 - 0.05 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 GHKL domain E2R135 PF11570.8 KEZ34534.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Response_reg PF00072.24 KEZ34535.1 - 5.8e-20 71.5 0.0 7.7e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 KEZ34536.1 - 7.6e-32 109.8 0.0 9.7e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 KEZ34536.1 - 3.8e-17 62.8 0.0 6.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KEZ34536.1 - 3.9e-10 39.9 2.0 6e-10 39.3 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KEZ34536.1 - 1.1e-07 32.0 0.0 3.7e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain HisKA PF00512.25 KEZ34536.1 - 4.7e-07 29.7 0.0 4.7e-07 29.7 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KEZ34536.1 - 5.7e-06 26.5 0.4 5.7e-06 26.5 0.4 2.3 2 0 0 2 2 2 1 PAS fold FleQ PF06490.11 KEZ34536.1 - 0.0052 17.1 0.0 0.084 13.2 0.0 2.9 3 1 0 3 3 3 1 Flagellar regulatory protein FleQ PAS PF00989.25 KEZ34536.1 - 0.038 14.0 0.0 0.2 11.6 0.0 2.3 1 1 0 1 1 1 0 PAS fold HPTransfase PF10090.9 KEZ34536.1 - 0.048 13.5 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain DUF2436 PF10365.9 KEZ34537.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF2436) DDE_3 PF13358.6 KEZ34538.1 - 8.1e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4089 PF13318.6 KEZ34538.1 - 0.014 15.9 0.1 0.87 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) TPR_12 PF13424.6 KEZ34542.1 - 0.025 14.9 5.7 0.056 13.7 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ34542.1 - 0.053 13.7 1.6 1.9 8.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.23 KEZ34543.1 - 3.5e-19 68.5 0.0 4.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Inv-AAD PF18785.1 KEZ34543.1 - 1.2e-16 60.7 0.0 9e-16 57.9 0.0 1.9 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase MafB19-deam PF14437.6 KEZ34543.1 - 4.8e-07 29.6 0.0 6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KEZ34543.1 - 0.098 12.5 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Ferrochelatase PF00762.19 KEZ34545.1 - 1.6e-79 267.3 0.0 1.8e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF3090 PF11290.8 KEZ34546.1 - 1.3e-53 181.3 0.0 1.5e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3090) SinI PF08671.10 KEZ34546.1 - 0.21 11.4 0.1 23 4.9 0.0 2.6 3 0 0 3 3 3 0 Anti-repressor SinI Lipase_GDSL_2 PF13472.6 KEZ34548.1 - 4.6e-22 79.3 0.1 5.7e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ34548.1 - 2.1e-06 27.8 0.0 2.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glycos_transf_1 PF00534.20 KEZ34549.1 - 1.9e-23 82.9 0.0 3.1e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ34549.1 - 1.6e-21 77.1 1.5 3.8e-21 75.9 1.5 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ34549.1 - 5e-18 66.0 16.5 5e-18 66.0 16.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ34549.1 - 6.8e-15 55.5 3.5 6.8e-15 55.5 3.5 2.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ34549.1 - 5.9e-07 29.8 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3880 PF12996.7 KEZ34549.1 - 0.04 14.0 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Glycos_transf_1 PF00534.20 KEZ34550.1 - 8e-21 74.3 0.0 1.2e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ34550.1 - 2.1e-18 66.9 7.7 3.8e-18 66.1 5.2 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEZ34550.1 - 6.1e-17 62.3 0.2 1.2e-16 61.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ34550.1 - 8.2e-12 45.9 17.7 8.2e-12 45.9 17.7 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ34550.1 - 0.00068 20.0 0.0 0.0043 17.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ34550.1 - 0.001 19.1 0.0 0.0037 17.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like DUF3099 PF11298.8 KEZ34551.1 - 2.1e-26 91.8 3.2 2.7e-26 91.5 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) SAM_adeno_trans PF01887.16 KEZ34552.1 - 3.2e-73 246.1 0.0 3.7e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase Uricase PF01014.18 KEZ34553.1 - 2.6e-56 189.5 0.0 1.5e-32 112.6 0.0 2.0 2 0 0 2 2 2 2 Uricase Big_10 PF17964.1 KEZ34554.1 - 1.5e-43 148.9 0.6 2.9e-43 148.0 0.4 1.6 1 1 1 2 2 2 1 Bacterial Ig domain YkuD PF03734.14 KEZ34554.1 - 5.5e-13 49.6 0.1 1.2e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 KEZ34554.1 - 5.5e-09 36.7 0.1 8.1e-05 23.3 1.1 2.5 2 0 0 2 2 2 2 Bacterial Ig-like domain PAP2_3 PF14378.6 KEZ34555.1 - 1.5e-59 200.9 13.6 1.5e-59 200.9 13.6 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KEZ34555.1 - 0.0093 15.7 9.6 0.022 14.5 8.2 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KEZ34555.1 - 0.1 13.2 0.0 0.1 13.2 0.0 2.7 3 1 0 3 3 3 0 PAP2 superfamily C-terminal OmpA PF00691.20 KEZ34556.1 - 3.1e-19 69.2 0.0 1.3e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 OmpA family BON PF04972.17 KEZ34556.1 - 0.38 11.1 12.8 0.36 11.2 2.1 3.8 3 1 0 3 3 3 0 BON domain DUF218 PF02698.17 KEZ34556.1 - 0.63 10.1 4.9 0.98 9.4 0.0 3.0 2 1 0 2 2 2 0 DUF218 domain Fer2_BFD PF04324.15 KEZ34558.1 - 3.7e-13 49.6 4.1 4.4e-13 49.3 4.1 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain GAF_3 PF13492.6 KEZ34561.1 - 0.01 16.2 0.1 3.5 8.0 0.0 2.7 2 1 1 3 3 3 0 GAF domain Bim_N PF06773.11 KEZ34561.1 - 0.13 12.0 0.2 0.32 10.7 0.2 1.7 1 0 0 1 1 1 0 Bim protein N-terminus DDE_Tnp_1 PF01609.21 KEZ34563.1 - 6e-07 29.3 0.0 7.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DUF2406 PF10295.9 KEZ34563.1 - 0.073 13.8 0.0 0.2 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) AfsA PF03756.13 KEZ34564.1 - 7.2e-50 168.4 4.4 8.7e-33 113.1 1.7 2.1 2 0 0 2 2 2 2 A-factor biosynthesis hotdog domain adh_short_C2 PF13561.6 KEZ34565.1 - 3.7e-52 177.2 1.8 6.2e-52 176.5 1.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ34565.1 - 2.1e-46 157.8 0.3 3.8e-46 157.0 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ34565.1 - 4.5e-14 52.8 1.8 1.9e-12 47.5 1.8 2.4 1 1 0 1 1 1 1 KR domain ABC_tran PF00005.27 KEZ34566.1 - 9.7e-52 175.1 0.0 4.1e-28 98.6 0.0 2.1 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 KEZ34566.1 - 8.1e-17 61.5 0.8 2e-10 41.0 0.2 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KEZ34566.1 - 1.1e-15 58.2 4.3 2.8e-06 27.4 0.0 4.1 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEZ34566.1 - 1.3e-08 35.2 0.1 0.0062 16.8 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEZ34566.1 - 8e-08 32.8 7.1 0.00031 21.2 0.4 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEZ34566.1 - 2.4e-05 24.0 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KEZ34566.1 - 3.3e-05 23.4 0.0 1.2 8.5 0.0 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KEZ34566.1 - 0.00015 21.2 0.4 0.41 10.0 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KEZ34566.1 - 0.00055 19.9 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KEZ34566.1 - 0.0012 18.6 0.2 0.54 10.0 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 KEZ34566.1 - 0.0012 19.2 0.0 0.029 14.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KEZ34566.1 - 0.0017 18.3 3.3 0.68 9.8 0.1 2.7 3 0 0 3 3 2 2 NACHT domain NB-ARC PF00931.22 KEZ34566.1 - 0.0048 16.1 0.0 0.85 8.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain DUF87 PF01935.17 KEZ34566.1 - 0.005 17.0 1.3 1.3 9.1 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 KEZ34566.1 - 0.0059 16.4 0.1 3.3 7.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KEZ34566.1 - 0.0068 16.6 0.0 11 6.3 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KEZ34566.1 - 0.0098 16.1 5.4 2.2 8.5 0.4 3.3 2 2 0 2 2 2 2 AAA domain CbiA PF01656.23 KEZ34566.1 - 0.01 15.9 0.5 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KEZ34566.1 - 0.012 15.3 4.1 0.26 11.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KEZ34566.1 - 0.014 14.8 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 KEZ34566.1 - 0.015 15.2 0.4 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KEZ34566.1 - 0.02 15.3 0.1 3.2 8.2 0.0 2.9 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 KEZ34566.1 - 0.033 13.9 0.1 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KEZ34566.1 - 0.036 13.3 0.9 2 7.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KEZ34566.1 - 0.041 13.6 1.0 2.7 7.6 0.1 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KEZ34566.1 - 0.049 13.7 1.5 1.7 8.8 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 KEZ34566.1 - 0.072 13.1 0.4 9.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KEZ34566.1 - 0.075 12.1 0.1 0.55 9.2 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_5 PF07728.14 KEZ34566.1 - 0.089 12.8 1.1 18 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEZ34566.1 - 0.24 11.8 0.5 9.5 6.7 0.1 2.2 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KEZ34566.1 - 0.48 10.7 4.0 0.87 9.8 0.4 2.8 2 1 0 3 3 3 0 AAA domain BPD_transp_1 PF00528.22 KEZ34567.1 - 4.7e-22 78.6 12.2 4.7e-22 78.6 12.2 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ost5 PF05251.12 KEZ34567.1 - 0.014 15.6 2.0 0.43 10.9 0.1 3.0 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 BPD_transp_1 PF00528.22 KEZ34568.1 - 3.5e-26 92.1 12.8 3.5e-26 92.1 12.8 2.2 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4396 PF14342.6 KEZ34568.1 - 7.9 6.8 9.6 9.8 6.5 3.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4396) SBP_bac_5 PF00496.22 KEZ34569.1 - 5.9e-72 242.7 0.0 7e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Abhydrolase_1 PF00561.20 KEZ34570.1 - 1e-20 74.5 0.0 1.3e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ34570.1 - 1.7e-14 53.6 0.0 5.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEZ34570.1 - 4.9e-05 23.4 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 KEZ34570.1 - 0.00029 19.6 0.0 0.00067 18.4 0.0 1.5 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 KEZ34570.1 - 0.0052 16.5 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KEZ34570.1 - 0.014 15.0 0.1 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KEZ34570.1 - 0.15 11.5 0.0 3 7.3 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Isochorismatase PF00857.20 KEZ34571.1 - 6.5e-32 111.1 0.3 7.4e-32 110.9 0.3 1.0 1 0 0 1 1 1 1 Isochorismatase family Catalase_C PF18011.1 KEZ34571.1 - 0.015 15.0 0.4 0.025 14.2 0.4 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases Putative_PNPOx PF01243.20 KEZ34572.1 - 3.5e-17 62.4 0.0 5.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KEZ34572.1 - 6.6e-05 22.9 0.0 7.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KEZ34572.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like FAD_binding_3 PF01494.19 KEZ34573.1 - 5.8e-71 239.6 0.0 7.1e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ34573.1 - 0.00045 19.5 0.0 0.0095 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ34573.1 - 0.0005 19.3 0.1 0.0014 17.8 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ34573.1 - 0.00078 18.3 0.1 0.0015 17.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ34573.1 - 0.0056 16.9 1.2 0.046 13.9 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ34573.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ34573.1 - 0.28 10.2 0.2 0.4 9.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SnoaL_2 PF12680.7 KEZ34573.1 - 0.31 11.7 4.3 0.58 10.8 0.0 3.1 3 0 0 3 3 3 0 SnoaL-like domain MFS_1 PF07690.16 KEZ34574.1 - 7.1e-34 117.3 51.2 8.6e-34 117.0 48.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Resolvase PF00239.21 KEZ34575.1 - 1.2e-06 28.7 0.0 1.3e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 KEZ34576.1 - 0.00028 21.2 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 KEZ34576.1 - 0.082 13.4 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Acetyltransf_3 PF13302.7 KEZ34578.1 - 1.5e-12 48.4 0.0 1.9e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ34578.1 - 3.2e-08 33.8 0.0 4.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEZ34578.1 - 5.1e-05 23.0 0.0 9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ34578.1 - 0.0096 16.3 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ34578.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MerR PF00376.23 KEZ34578.1 - 0.067 13.0 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 MerR family regulatory protein Transglut_core3 PF13471.6 KEZ34579.1 - 1.1e-18 67.2 6.9 1.9e-18 66.5 6.9 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DDE_Tnp_IS66 PF03050.14 KEZ34580.1 - 1.1e-05 25.1 0.2 1.4e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 KEZ34580.1 - 0.02 15.1 0.1 0.038 14.2 0.1 1.5 1 1 0 1 1 1 0 IS66 C-terminal element DDE_5 PF13546.6 KEZ34581.1 - 1.9e-37 129.1 0.8 1.9e-37 129.1 0.8 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ34581.1 - 0.0005 19.8 0.0 0.0036 17.0 0.0 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KEZ34582.1 - 2.2e-12 47.2 0.4 2.6e-12 46.9 0.4 1.1 1 0 0 1 1 1 1 Transposase DDE domain HTH_15 PF12324.8 KEZ34582.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase HTH_29 PF13551.6 KEZ34583.1 - 1.8e-13 50.2 0.0 1.8e-13 50.2 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 KEZ34583.1 - 2.8e-13 50.3 6.0 2.3e-12 47.4 1.0 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 KEZ34583.1 - 3.8e-11 42.9 3.4 7.8e-11 41.9 0.1 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ34583.1 - 1.6e-05 24.5 0.5 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 KEZ34583.1 - 0.04 13.6 0.2 0.21 11.2 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Uma2 PF05685.12 KEZ34584.1 - 8.1e-20 71.1 0.1 9e-20 70.9 0.1 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Spc24 PF08286.11 KEZ34585.1 - 0.052 13.8 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Nterm_IS4 PF13006.7 KEZ34586.1 - 7.6e-35 119.0 0.1 1.6e-34 118.0 0.1 1.6 1 0 0 1 1 1 1 Insertion element 4 transposase N-terminal DDE_Tnp_1 PF01609.21 KEZ34586.1 - 1.6e-12 47.6 0.0 3e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Transposase DDE domain YdjM PF04307.14 KEZ34588.1 - 1.1e-38 132.2 18.2 7.9e-38 129.5 18.2 1.9 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase PNTB_4TM PF12769.7 KEZ34588.1 - 2.4 8.7 7.5 1.3 9.6 0.5 3.1 3 1 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF2784 PF10861.8 KEZ34589.1 - 4e-35 120.2 4.5 4.5e-35 120.1 4.5 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF2784) AA_permease_2 PF13520.6 KEZ34589.1 - 0.2 10.5 2.3 0.64 8.8 1.1 1.9 2 0 0 2 2 2 0 Amino acid permease BPL_LplA_LipB PF03099.19 KEZ34590.1 - 3.6e-05 23.7 0.0 5.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.25 KEZ34591.1 - 2.3e-37 128.8 0.0 3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ34591.1 - 1.2e-21 77.2 0.0 1.6e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ34591.1 - 0.0022 16.8 0.0 0.0031 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEZ34591.1 - 0.0071 16.3 0.5 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEZ34591.1 - 0.014 14.8 0.0 0.043 13.1 0.0 1.7 2 1 0 2 2 2 0 Kinase-like 2OG-FeII_Oxy_2 PF13532.6 KEZ34592.1 - 9e-12 45.6 0.0 1.3e-11 45.1 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HATPase_c_2 PF13581.6 KEZ34593.1 - 5.5e-07 29.6 0.2 9.2e-07 28.9 0.2 1.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ34593.1 - 0.054 14.0 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ApbE PF02424.15 KEZ34593.1 - 0.066 12.7 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 ApbE family EAL PF00563.20 KEZ34594.1 - 1.6e-46 158.7 0.0 2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 EAL domain GAF_2 PF13185.6 KEZ34594.1 - 1.1e-09 38.7 0.6 3.1e-09 37.3 0.3 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KEZ34594.1 - 9e-08 32.8 0.1 3.6e-07 30.9 0.1 2.0 3 0 0 3 3 3 1 GAF domain Usp PF00582.26 KEZ34595.1 - 3.3e-41 141.1 7.3 8.1e-19 68.5 0.3 3.2 3 0 0 3 3 3 3 Universal stress protein family Hemerythrin PF01814.23 KEZ34597.1 - 1.4e-09 38.7 8.7 2.7e-09 37.7 8.7 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain FANC_SAP PF18081.1 KEZ34597.1 - 0.015 15.4 1.1 0.041 14.1 0.3 2.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DUF1772 PF08592.11 KEZ34598.1 - 0.12 12.7 9.0 0.88 9.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Pex24p PF06398.11 KEZ34598.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin 7TMR-DISM_7TM PF07695.11 KEZ34598.1 - 0.44 10.4 8.2 0.81 9.5 8.2 1.3 1 1 0 1 1 1 0 7TM diverse intracellular signalling E1-E2_ATPase PF00122.20 KEZ34598.1 - 1.3 8.5 9.0 0.18 11.3 2.5 1.9 1 1 1 2 2 2 0 E1-E2 ATPase Gram_pos_anchor PF00746.21 KEZ34598.1 - 3.1 7.8 0.0 3.1 7.8 0.0 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif FA_desaturase PF00487.24 KEZ34598.1 - 3.3 7.5 6.5 3 7.6 4.5 1.7 1 1 1 2 2 2 0 Fatty acid desaturase dCMP_cyt_deam_1 PF00383.23 KEZ34600.1 - 1.3e-18 66.8 0.0 1.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Inv-AAD PF18785.1 KEZ34600.1 - 2e-17 63.2 0.1 3e-16 59.4 0.1 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase MafB19-deam PF14437.6 KEZ34600.1 - 1.5e-06 28.0 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KEZ34600.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.6 KEZ34600.1 - 0.07 13.2 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Phage_int_SAM_1 PF02899.17 KEZ34601.1 - 0.0022 18.3 0.0 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain RHH_1 PF01402.21 KEZ34602.1 - 1e-07 31.6 0.1 1.7e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family BrnA_antitoxin PF14384.6 KEZ34602.1 - 0.013 16.0 0.0 0.016 15.7 0.0 1.2 1 1 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system DDE_3 PF13358.6 KEZ34603.1 - 8.2e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KEZ34603.1 - 0.0029 18.2 3.3 0.055 14.1 1.1 2.5 1 1 1 2 2 2 2 Homeodomain-like domain NTP_transf_2 PF01909.23 KEZ34604.1 - 7.9e-14 51.7 0.4 1.1e-13 51.3 0.4 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEZ34604.1 - 2.3e-13 50.0 0.0 2.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RlaP PF10127.9 KEZ34604.1 - 0.15 11.6 0.2 0.17 11.4 0.2 1.1 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family DUF86 PF01934.17 KEZ34605.1 - 1.8e-22 79.5 0.0 2.1e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 MerR_1 PF13411.6 KEZ34606.1 - 1.7e-15 56.8 0.0 2.4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ34606.1 - 3.8e-13 49.0 0.3 9.8e-12 44.4 0.1 2.3 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KEZ34606.1 - 9.9e-05 22.8 0.3 0.00014 22.3 0.3 1.2 1 0 0 1 1 1 1 MerR, DNA binding Bac_luciferase PF00296.20 KEZ34607.1 - 6.7e-50 170.3 6.6 8.3e-50 170.0 6.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FMN_red PF03358.15 KEZ34609.1 - 5.3e-38 130.2 0.1 6.7e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEZ34609.1 - 8.9e-08 32.1 0.1 1.4e-07 31.4 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KEZ34609.1 - 0.00017 21.9 0.1 0.00033 20.9 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin domain DAO PF01266.24 KEZ34610.1 - 2.3e-62 211.6 8.7 3.6e-62 211.0 8.7 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ34610.1 - 0.00022 21.4 0.5 0.00058 20.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ34610.1 - 0.0084 16.6 0.2 0.048 14.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KEZ34610.1 - 0.016 13.8 0.1 2.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) PTH2 PF01981.16 KEZ34610.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Glyco_hydro_15 PF00723.21 KEZ34611.1 - 9.8e-65 219.1 0.0 2.7e-57 194.6 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPR_2 PF07719.17 KEZ34611.1 - 0.015 15.4 0.1 0.039 14.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ34611.1 - 0.063 13.9 0.1 0.4 11.4 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ34611.1 - 0.085 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PGPGW PF09656.10 KEZ34613.1 - 4.3e-20 71.0 2.5 4.3e-20 71.0 2.5 2.6 2 1 0 2 2 2 1 Putative transmembrane protein (PGPGW) MSP1a PF11670.8 KEZ34613.1 - 0.0029 17.0 0.3 0.0039 16.5 0.3 1.1 1 0 0 1 1 1 1 Major surface protein 1a (MSP1a) DUF5337 PF17272.2 KEZ34613.1 - 0.0064 16.3 4.5 0.0064 16.3 4.5 2.6 2 1 1 3 3 3 1 Family of unknown function (DUF5337) UcrQ PF02939.16 KEZ34613.1 - 0.027 14.4 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 UcrQ family UbiA PF01040.18 KEZ34613.1 - 0.038 13.3 10.2 0.096 12.0 0.9 2.1 1 1 1 2 2 2 0 UbiA prenyltransferase family CrgA PF06781.12 KEZ34613.1 - 0.057 13.5 0.1 0.057 13.5 0.1 2.7 1 1 1 2 2 2 0 Cell division protein CrgA 3HCDH_N PF02737.18 KEZ34613.1 - 0.21 11.5 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3784 PF12650.7 KEZ34613.1 - 0.22 11.8 3.6 0.12 12.6 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) CRF PF00473.17 KEZ34613.1 - 0.44 10.7 2.3 0.88 9.7 2.3 1.5 1 0 0 1 1 1 0 Corticotropin-releasing factor family DUF4231 PF14015.6 KEZ34613.1 - 0.71 10.4 4.5 0.85 10.1 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF2269 PF10027.9 KEZ34613.1 - 0.78 9.8 5.8 0.46 10.5 2.4 1.9 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) Neurensin PF14927.6 KEZ34613.1 - 1.2 8.9 4.6 16 5.2 4.6 2.6 1 1 0 1 1 1 0 Neurensin Phage_holin_3_6 PF07332.11 KEZ34613.1 - 1.5 8.9 17.6 0.057 13.5 2.6 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1206 PF06724.11 KEZ34613.1 - 2.9 8.0 18.5 2 8.6 3.8 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1206) TrkA_C PF02080.21 KEZ34614.1 - 5.7e-18 64.5 0.1 1.2e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 TrkA-C domain Na_H_Exchanger PF00999.21 KEZ34615.1 - 5e-44 150.6 35.9 6.3e-44 150.3 35.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SirB PF04247.12 KEZ34615.1 - 0.59 10.2 6.0 0.17 12.0 2.3 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB adh_short_C2 PF13561.6 KEZ34616.1 - 2.1e-65 220.5 0.0 2.4e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ34616.1 - 5.9e-16 58.5 0.0 7.4e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ34616.1 - 0.052 13.4 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF167 PF02594.16 KEZ34618.1 - 3.8e-20 71.8 0.1 9.2e-20 70.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 RNase_II_C_S1 PF18614.1 KEZ34618.1 - 0.4 10.7 9.5 22 5.1 9.5 2.4 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain adh_short_C2 PF13561.6 KEZ34619.1 - 5.5e-56 189.7 4.2 9.8e-56 188.9 4.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ34619.1 - 8.5e-47 159.1 2.1 1.7e-46 158.1 2.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ34619.1 - 1.2e-17 64.4 2.1 5.2e-16 59.1 1.7 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ34619.1 - 1.4e-05 24.7 0.1 2.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ34619.1 - 0.081 12.0 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Cation_efflux PF01545.21 KEZ34620.1 - 7.1e-37 127.1 12.6 9.1e-37 126.7 12.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEZ34620.1 - 5.6e-13 48.8 0.9 2.5e-12 46.7 0.3 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF2104 PF09877.9 KEZ34620.1 - 0.013 15.7 0.9 0.028 14.7 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) ETRAMP PF09716.10 KEZ34620.1 - 0.21 11.7 0.0 1.1 9.4 0.0 2.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Phage_holin_3_1 PF05106.12 KEZ34620.1 - 0.44 11.0 3.8 0.48 10.9 0.4 2.6 2 1 0 2 2 2 0 Phage holin family (Lysis protein S) DUF397 PF04149.12 KEZ34623.1 - 3e-06 27.2 0.1 4.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF397) rve PF00665.26 KEZ34625.1 - 2.4e-22 79.4 0.0 4.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KEZ34625.1 - 2.4e-13 49.7 0.1 5.7e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KEZ34625.1 - 2.6e-06 27.7 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DDE domain HTH_32 PF13565.6 KEZ34625.1 - 1.2e-05 25.8 3.1 4.8e-05 23.9 3.1 2.1 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KEZ34625.1 - 0.00036 20.5 0.2 0.41 10.7 0.0 3.1 3 0 0 3 3 3 2 Winged helix-turn helix Polyketide_cyc2 PF10604.9 KEZ34625.1 - 0.024 14.9 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Bap31_Bap29_C PF18035.1 KEZ34626.1 - 0.1 12.6 0.8 0.17 11.9 0.8 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DEDD_Tnp_IS110 PF01548.17 KEZ34627.1 - 1.4e-24 86.8 0.0 2.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 KEZ34627.1 - 2.3e-20 72.7 0.1 6e-20 71.4 0.1 1.7 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family MerR-DNA-bind PF09278.11 KEZ34627.1 - 0.37 11.3 0.2 0.37 11.3 0.2 3.2 4 0 0 4 4 4 0 MerR, DNA binding Resolvase PF00239.21 KEZ34628.1 - 0.0048 17.0 0.1 0.015 15.4 0.1 1.7 2 0 0 2 2 2 1 Resolvase, N terminal domain DUF4926 PF16277.5 KEZ34628.1 - 0.09 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) PhzC-PhzF PF02567.16 KEZ34629.1 - 4e-54 184.0 0.0 4.7e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KEZ34629.1 - 0.02 13.9 0.0 0.055 12.5 0.0 1.6 2 0 0 2 2 2 0 Proline racemase NfeD PF01957.18 KEZ34629.1 - 0.13 12.7 0.1 0.35 11.3 0.1 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Reg_prop PF07494.11 KEZ34629.1 - 0.15 12.3 0.2 0.41 11.0 0.2 1.7 1 0 0 1 1 1 0 Two component regulator propeller DUF1003 PF06210.11 KEZ34630.1 - 2.9e-23 81.9 0.0 5.1e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) p450 PF00067.22 KEZ34631.1 - 2.3e-18 66.2 0.0 1.1e-12 47.5 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 OrfB_Zn_ribbon PF07282.11 KEZ34632.1 - 5.8e-20 71.0 0.0 1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 KEZ34632.1 - 2.8e-11 43.7 0.1 2.1e-06 27.9 0.0 2.7 1 1 1 2 2 2 2 Probable transposase DZR PF12773.7 KEZ34632.1 - 0.063 13.3 0.7 0.11 12.5 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon HTH_6 PF01418.17 KEZ34633.1 - 2e-17 63.0 0.0 7.6e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 KEZ34633.1 - 2.9e-17 62.7 1.1 4e-17 62.3 1.1 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KEZ34633.1 - 2.1e-07 31.0 0.8 0.024 14.7 0.2 2.4 1 1 1 2 2 2 2 SIS domain HTH_IclR PF09339.10 KEZ34633.1 - 4.1e-05 23.3 0.2 0.0018 18.1 0.0 2.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ34633.1 - 0.0055 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KEZ34633.1 - 0.027 14.4 2.5 0.32 10.9 0.0 3.2 3 0 0 3 3 3 0 MarR family T3SS_needle_E PF08988.10 KEZ34633.1 - 0.036 14.2 0.4 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle GspH PF12019.8 KEZ34634.1 - 0.0023 18.3 0.0 0.0026 18.2 0.0 1.1 1 0 0 1 1 1 1 Type II transport protein GspH YkuD PF03734.14 KEZ34637.1 - 6.7e-19 68.7 0.0 1.5e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain TetR_C_1 PF02909.17 KEZ34638.1 - 1.5e-11 44.3 0.0 1.7e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Condensation PF00668.20 KEZ34639.1 - 9e-68 229.0 0.0 1.1e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Condensation domain DDE_Tnp_1 PF01609.21 KEZ34640.1 - 9.4e-05 22.1 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain MarR PF01047.22 KEZ34642.1 - 5.2e-09 35.9 0.2 7.4e-08 32.2 0.2 2.1 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KEZ34642.1 - 4e-08 33.6 1.6 6.8e-08 32.9 0.6 1.9 2 1 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 KEZ34642.1 - 6e-08 32.5 1.6 1.2e-07 31.5 1.6 1.6 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KEZ34642.1 - 0.00067 19.7 1.2 0.0021 18.1 1.2 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain TetR_C_35 PF18556.1 KEZ34642.1 - 0.0064 16.6 1.5 0.039 14.1 0.1 2.2 1 1 0 2 2 2 1 Bacterial Tetracyclin repressor, C-terminal domain Acetyltransf_3 PF13302.7 KEZ34643.1 - 3e-20 73.3 0.1 4.1e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ34643.1 - 7e-08 32.7 0.0 9.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEZ34643.1 - 0.0089 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEZ34643.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SHOCT PF09851.9 KEZ34644.1 - 8e-09 35.0 1.1 1.1e-08 34.5 1.1 1.3 1 0 0 1 1 1 1 Short C-terminal domain VbhA PF18495.1 KEZ34644.1 - 0.00043 20.1 0.8 0.00064 19.5 0.8 1.3 1 0 0 1 1 1 1 Antitoxin VbhA DUF1707 PF08044.11 KEZ34644.1 - 0.011 15.8 1.8 0.018 15.1 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) ASFV_J13L PF05568.11 KEZ34644.1 - 0.078 12.7 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein PspA_IM30 PF04012.12 KEZ34645.1 - 3.7e-26 92.1 24.4 4.4e-26 91.8 24.4 1.0 1 0 0 1 1 1 1 PspA/IM30 family Flagellin_C PF00700.21 KEZ34645.1 - 0.00037 20.8 8.3 0.35 11.2 0.1 3.3 2 1 1 3 3 3 2 Bacterial flagellin C-terminal helical region Jnk-SapK_ap_N PF09744.9 KEZ34645.1 - 0.02 15.1 7.6 0.019 15.2 6.5 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Snf7 PF03357.21 KEZ34645.1 - 0.02 14.5 5.9 3.3 7.3 5.9 2.3 1 1 0 1 1 1 0 Snf7 Syntaxin PF00804.25 KEZ34645.1 - 0.022 14.4 5.0 0.036 13.7 5.0 1.5 1 1 0 1 1 1 0 Syntaxin Filament PF00038.21 KEZ34645.1 - 0.027 14.1 11.9 0.84 9.2 5.3 2.5 1 1 1 2 2 2 0 Intermediate filament protein Sec34 PF04136.15 KEZ34645.1 - 0.029 14.3 0.4 2.1 8.2 0.1 2.4 2 1 0 2 2 2 0 Sec34-like family GCN5L1 PF06320.13 KEZ34645.1 - 0.03 14.5 0.3 0.03 14.5 0.3 3.0 3 1 1 4 4 4 0 GCN5-like protein 1 (GCN5L1) Seryl_tRNA_N PF02403.22 KEZ34645.1 - 0.06 13.6 7.1 0.2 11.9 1.3 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 KEZ34645.1 - 0.067 13.5 2.7 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ADIP PF11559.8 KEZ34645.1 - 0.1 12.7 11.5 0.028 14.5 5.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KEZ34645.1 - 0.11 13.2 2.9 6.3 7.5 0.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 KEZ34645.1 - 0.13 12.3 2.3 10 6.2 0.2 2.7 3 1 0 3 3 2 0 Protein of unknown function (DUF1664) RIP PF00161.19 KEZ34645.1 - 0.14 11.7 1.5 2.1 7.9 0.2 2.2 1 1 1 2 2 2 0 Ribosome inactivating protein CENP-F_leu_zip PF10473.9 KEZ34645.1 - 0.15 12.0 7.2 0.26 11.3 2.3 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 KEZ34645.1 - 0.2 12.1 5.0 0.97 9.9 0.6 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 KEZ34645.1 - 0.55 9.1 7.8 1.5 7.7 7.6 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Flagellin_N PF00669.20 KEZ34645.1 - 0.78 9.8 9.8 0.15 12.2 0.5 2.7 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region APG6_N PF17675.1 KEZ34645.1 - 1 9.9 17.6 0.85 10.2 11.4 2.8 3 1 0 3 3 2 0 Apg6 coiled-coil region AP1AR PF15745.5 KEZ34645.1 - 1.7 8.2 8.6 2.5 7.7 8.6 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DivIC PF04977.15 KEZ34645.1 - 2.6 7.9 11.5 3.2 7.6 0.5 2.9 3 0 0 3 3 3 0 Septum formation initiator DivIVA PF05103.13 KEZ34645.1 - 2.7 8.1 8.7 2 8.5 3.9 2.6 1 1 2 3 3 3 0 DivIVA protein TPR_MLP1_2 PF07926.12 KEZ34645.1 - 6.3 6.9 16.3 7.1 6.7 12.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_M48 PF01435.18 KEZ34647.1 - 2.4e-29 102.5 0.0 5.9e-29 101.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KEZ34647.1 - 0.00031 20.0 0.1 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 1 BlaR1 peptidase M56 Peptidase_M48 PF01435.18 KEZ34649.1 - 2.6e-13 50.2 1.3 2.3e-11 43.8 0.1 2.4 1 1 1 2 2 2 2 Peptidase family M48 Peptidase_M56 PF05569.11 KEZ34649.1 - 3.6e-05 23.1 0.0 6.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 SLAC1 PF03595.17 KEZ34649.1 - 0.52 9.5 9.6 0.13 11.5 5.7 1.8 2 0 0 2 2 2 0 Voltage-dependent anion channel Penicillinase_R PF03965.16 KEZ34650.1 - 1e-17 64.5 0.0 1.2e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Penicillinase repressor PaaX PF07848.12 KEZ34650.1 - 0.025 14.8 0.1 0.049 13.8 0.0 1.6 2 0 0 2 2 2 0 PaaX-like protein ABC_tran PF00005.27 KEZ34651.1 - 2.6e-23 83.0 0.0 3.9e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ34651.1 - 3.1e-15 56.8 0.1 2.8e-09 37.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ34651.1 - 0.0039 17.7 0.0 0.0052 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ34651.1 - 0.014 15.1 0.0 0.075 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ34651.1 - 0.018 15.4 0.1 0.037 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KEZ34651.1 - 0.04 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KEZ34651.1 - 0.055 13.2 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KEZ34651.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KEZ34651.1 - 0.16 11.4 0.0 2.5 7.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ34651.1 - 0.2 11.9 0.1 3 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 KEZ34652.1 - 2.6e-12 46.6 11.6 5.4e-12 45.6 11.5 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KEZ34652.1 - 4.5e-12 46.3 1.3 7.7e-12 45.5 1.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 KEZ34652.1 - 0.00044 19.7 7.1 0.00091 18.7 7.1 1.4 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ34652.1 - 0.067 12.3 9.7 0.1 11.7 9.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SymE_toxin PF08845.10 KEZ34652.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system DUF1964 PF09244.10 KEZ34653.1 - 0.044 14.2 0.1 0.091 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1964) Hydantoinase_A PF01968.18 KEZ34654.1 - 1e-64 218.6 3.1 2e-64 217.6 0.6 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ34654.1 - 5.1e-21 75.2 2.8 6e-19 68.4 0.2 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KEZ34654.1 - 0.13 10.9 3.1 3.2 6.2 0.5 2.2 2 0 0 2 2 2 0 MutL protein Acetone_carb_G PF08882.11 KEZ34655.1 - 3e-42 143.4 0.2 3.4e-42 143.2 0.2 1.0 1 0 0 1 1 1 1 Acetone carboxylase gamma subunit TF_Zn_Ribbon PF08271.12 KEZ34655.1 - 0.0021 17.5 0.3 0.06 12.9 0.1 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding YhfH PF14149.6 KEZ34655.1 - 0.022 14.7 0.4 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 YhfH-like protein DZR PF12773.7 KEZ34655.1 - 0.061 13.4 0.9 0.26 11.3 0.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KEZ34655.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 KEZ34655.1 - 0.093 12.7 5.0 0.83 9.6 0.6 2.6 2 1 0 2 2 2 0 Nudix N-terminal Sgf11 PF08209.11 KEZ34655.1 - 0.12 11.9 1.6 7.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-MIZ PF02891.20 KEZ34655.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zinc_ribbon_2 PF13240.6 KEZ34655.1 - 0.13 12.0 3.1 1.7 8.5 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.11 KEZ34655.1 - 0.2 11.7 0.4 0.2 11.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-Mss51 PF13824.6 KEZ34655.1 - 0.34 11.0 2.5 10 6.3 2.3 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 YLP PF02757.17 KEZ34655.1 - 0.82 9.8 4.1 2.6 8.3 1.8 2.3 2 0 0 2 2 2 0 YLP motif C1_2 PF03107.16 KEZ34655.1 - 2.5 8.5 0.0 2.5 8.5 0.0 3.0 3 0 0 3 3 3 0 C1 domain DUF2752 PF10825.8 KEZ34655.1 - 3.1 7.9 6.3 0.24 11.5 1.6 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2752) Hydantoinase_A PF01968.18 KEZ34656.1 - 2.4e-74 250.2 0.0 1.1e-71 241.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ34656.1 - 6.7e-36 123.6 0.3 6.7e-36 123.6 0.3 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region ADH_zinc_N PF00107.26 KEZ34657.1 - 1.4e-24 86.5 0.2 2.5e-24 85.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ34657.1 - 3.1e-23 81.7 0.4 7e-23 80.6 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEZ34657.1 - 5.7e-12 46.8 0.0 9.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gpr1_Fun34_YaaH PF01184.19 KEZ34658.1 - 2.7e-12 46.8 15.7 3.5e-12 46.4 15.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Hydantoinase_B PF02538.14 KEZ34659.1 - 2.8e-76 257.0 0.1 3.4e-76 256.7 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Thiolase_N PF00108.23 KEZ34661.1 - 7.6e-17 61.5 0.0 8.2e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KEZ34661.1 - 4.2e-07 29.8 2.2 3.5e-05 23.5 1.6 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KEZ34661.1 - 3.1e-06 26.9 1.3 6.5e-06 25.9 1.3 1.7 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III BcrAD_BadFG PF01869.20 KEZ34661.1 - 0.057 12.9 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DDE_Tnp_IS66 PF03050.14 KEZ34662.1 - 7e-05 22.4 0.0 8.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family Cupin_4 PF08007.12 KEZ34663.1 - 1.1e-27 97.4 0.1 1.3e-27 97.1 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KEZ34663.1 - 3e-09 37.0 0.0 3.1e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KEZ34663.1 - 0.013 15.2 0.4 0.051 13.3 0.0 2.2 3 0 0 3 3 3 0 Cupin domain Aldo_ket_red PF00248.21 KEZ34664.1 - 1.9e-12 47.0 0.0 7.2e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF397 PF04149.12 KEZ34666.1 - 7.9e-24 83.5 0.4 9.2e-24 83.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KEZ34667.1 - 4.5e-15 55.7 2.7 8.7e-15 54.8 2.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ34667.1 - 0.0023 17.9 0.1 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34667.1 - 0.021 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_37 PF13744.6 KEZ34667.1 - 0.068 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 KEZ34667.1 - 0.25 11.2 1.9 0.45 10.4 0.9 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HATPase_c_2 PF13581.6 KEZ34669.1 - 7.9e-12 45.2 0.1 1.5e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ34669.1 - 0.029 14.9 0.0 0.045 14.3 0.0 1.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_31 PF13560.6 KEZ34670.1 - 3.7e-06 27.2 2.9 2.3e-05 24.6 0.8 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ34670.1 - 0.45 10.4 2.4 7.4 6.5 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain DUF4096 PF13340.6 KEZ34671.1 - 5.6e-21 74.6 0.2 7.3e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) HTH_Tnp_4 PF13613.6 KEZ34671.1 - 0.0016 18.1 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 KEZ34672.1 - 3.3e-07 30.6 0.1 3.7e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ34672.1 - 0.0041 16.8 0.2 0.0042 16.7 0.2 1.0 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 KEZ34674.1 - 2.9e-08 33.6 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Transposase domain (DUF772) FliT PF05400.13 KEZ34674.1 - 0.018 15.8 3.0 0.018 15.8 3.0 1.7 2 0 0 2 2 2 0 Flagellar protein FliT DUF772 PF05598.11 KEZ34675.1 - 6.3e-14 51.7 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 KEZ34676.1 - 1.6e-28 99.4 0.4 2.4e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ34676.1 - 0.0001 22.0 0.0 0.00025 20.8 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 KEZ34677.1 - 1.7e-18 67.1 0.3 2.3e-18 66.6 0.3 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ34677.1 - 0.00026 20.7 3.4 0.099 12.3 0.8 2.1 2 0 0 2 2 2 2 Transposase DDE domain Whib PF02467.16 KEZ34677.1 - 0.032 14.8 0.6 0.076 13.6 0.6 1.6 1 0 0 1 1 1 0 Transcription factor WhiB HTH_32 PF13565.6 KEZ34679.1 - 2.2e-18 66.6 3.8 6.7e-18 65.1 3.8 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 KEZ34679.1 - 8.2e-15 54.8 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 KEZ34679.1 - 8.7e-14 51.3 2.2 7.4e-13 48.3 2.6 2.4 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 KEZ34679.1 - 1.9e-08 33.9 3.8 1.7e-06 27.7 0.2 3.4 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 KEZ34679.1 - 1.8e-06 27.9 2.5 8.9e-06 25.7 1.9 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 KEZ34679.1 - 0.0001 22.1 0.1 0.00027 20.8 0.1 1.8 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) NAD_binding_1 PF00175.21 KEZ34679.1 - 0.024 15.3 0.0 0.043 14.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain GerE PF00196.19 KEZ34679.1 - 0.028 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 KEZ34679.1 - 0.033 14.0 0.1 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KEZ34679.1 - 0.34 11.2 2.0 2.8 8.3 1.1 2.5 2 1 1 3 3 3 0 Transposase Phage_integrase PF00589.22 KEZ34681.1 - 2.2e-12 47.1 0.0 5.6e-07 29.5 0.0 3.2 2 1 0 2 2 2 2 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ34681.1 - 5.1e-06 26.7 0.0 2.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KEZ34681.1 - 0.006 17.0 0.0 0.021 15.3 0.0 1.9 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DDE_3 PF13358.6 KEZ34683.1 - 3.3e-15 56.1 0.0 9.1e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_33 PF13592.6 KEZ34684.1 - 9.7e-24 82.8 2.2 1.7e-23 82.0 0.9 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KEZ34684.1 - 1.1e-09 37.7 4.0 2.8e-09 36.5 1.5 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 KEZ34684.1 - 2e-09 37.9 1.4 2e-09 37.9 1.4 3.1 2 1 2 4 4 4 1 Homeodomain-like domain HTH_29 PF13551.6 KEZ34684.1 - 1.3e-07 31.5 2.4 1.3e-06 28.3 0.9 2.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KEZ34684.1 - 1.4e-07 31.5 1.2 1.4e-07 31.5 1.2 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ34684.1 - 0.0035 16.7 0.7 0.011 15.1 0.7 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 KEZ34684.1 - 0.039 13.6 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 KEZ34684.1 - 0.053 13.1 0.1 2.2 7.9 0.1 2.8 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 KEZ34684.1 - 0.087 12.6 0.1 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease LZ_Tnp_IS481 PF13011.6 KEZ34684.1 - 0.12 12.9 3.4 0.62 10.6 0.5 2.7 2 1 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 KEZ34684.1 - 0.13 12.1 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain tRNA-synt_1b PF00579.25 KEZ34685.1 - 2.3e-51 174.9 0.0 2.9e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Radical_SAM PF04055.21 KEZ34687.1 - 4.2e-16 59.8 0.0 8.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 KEZ34687.1 - 4.7e-08 33.1 0.0 9.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Amidohydro_2 PF04909.14 KEZ34687.1 - 0.013 15.3 0.2 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase HTH_Tnp_1 PF01527.20 KEZ34688.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Transposase AMP-binding PF00501.28 KEZ34689.1 - 2.8e-183 609.3 0.0 3.1e-93 312.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KEZ34689.1 - 2e-81 274.0 0.0 2.6e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KEZ34689.1 - 4.7e-09 36.5 0.0 9.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DDE_3 PF13358.6 KEZ34692.1 - 7.1e-15 55.0 0.0 1.3e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KEZ34693.1 - 3.3e-22 77.9 0.7 3.3e-22 77.9 0.7 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KEZ34693.1 - 3.8e-08 33.8 0.7 3.8e-08 33.8 0.7 2.6 1 1 2 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KEZ34693.1 - 2.2e-07 30.5 0.9 2.2e-07 30.5 0.9 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 KEZ34693.1 - 2.7e-06 27.4 1.2 1.2e-05 25.3 1.2 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KEZ34693.1 - 4e-06 26.8 1.2 4e-06 26.8 1.2 2.8 2 1 1 3 3 3 1 Winged helix-turn helix CENP-B_N PF04218.13 KEZ34693.1 - 0.15 11.7 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DDE_Tnp_IS66 PF03050.14 KEZ34694.1 - 7.2e-28 97.8 2.2 8.8e-28 97.6 2.2 1.1 1 0 0 1 1 1 1 Transposase IS66 family zf-IS66 PF13005.7 KEZ34694.1 - 5.4e-06 26.7 5.6 9.5e-06 25.9 5.6 1.4 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 Phage_integrase PF00589.22 KEZ34695.1 - 2.3e-23 82.9 0.1 4.8e-23 81.8 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ34695.1 - 3.5e-13 49.7 4.3 3.5e-13 49.7 4.3 2.7 3 1 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KEZ34695.1 - 1.6e-06 28.5 0.4 4.1e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 KEZ34695.1 - 7.7e-05 23.0 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_integrase PF00589.22 KEZ34696.1 - 8.6e-17 61.4 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_integrase PF00589.22 KEZ34697.1 - 5.6e-26 91.4 0.0 8.3e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ34697.1 - 6.2e-11 42.4 0.0 5.7e-09 36.1 0.0 2.7 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain DDE_Tnp_IS66 PF03050.14 KEZ34698.1 - 4.2e-15 56.0 0.0 4.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family HTH_31 PF13560.6 KEZ34701.1 - 1e-11 45.0 5.9 1e-11 45.0 5.9 5.0 4 3 1 5 5 5 1 Helix-turn-helix domain TPR_MalT PF17874.1 KEZ34701.1 - 1.3e-09 37.9 18.3 1.6e-05 24.5 2.4 2.4 2 0 0 2 2 2 2 MalT-like TPR region HTH_3 PF01381.22 KEZ34701.1 - 4.2e-09 36.3 0.1 1.1e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix TPR_12 PF13424.6 KEZ34701.1 - 3.9e-06 27.1 5.4 3.9e-06 27.1 5.4 6.7 7 1 1 8 8 8 1 Tetratricopeptide repeat HTH_19 PF12844.7 KEZ34701.1 - 1.4e-05 25.0 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ34701.1 - 0.00022 21.6 0.0 0.0006 20.2 0.0 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TPR_19 PF14559.6 KEZ34701.1 - 0.00071 20.0 0.3 0.00071 20.0 0.3 5.6 4 2 2 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.9 KEZ34701.1 - 0.0011 18.7 0.1 2.2 8.0 0.0 2.7 1 1 1 2 2 2 2 26S proteasome subunit RPN7 TPR_2 PF07719.17 KEZ34701.1 - 0.0046 17.0 27.5 0.15 12.2 0.5 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ34701.1 - 0.014 15.4 5.2 8.4 6.7 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ34701.1 - 0.051 13.4 0.1 0.051 13.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ34701.1 - 0.08 13.2 4.4 4.5 7.7 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ34701.1 - 0.18 11.6 2.0 8.5 6.2 0.2 2.9 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KEZ34701.1 - 0.32 11.7 58.4 0.13 13.0 1.7 6.6 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ34701.1 - 0.57 11.0 0.0 0.57 11.0 0.0 10.4 11 2 1 12 12 12 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ34701.1 - 0.59 11.1 46.7 2.4 9.2 1.0 9.1 6 3 4 10 10 9 0 Tetratricopeptide repeat TPR_21 PF09976.9 KEZ34701.1 - 0.67 9.6 0.0 0.67 9.6 0.0 3.8 2 1 3 5 5 5 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KEZ34701.1 - 5 8.0 12.5 17 6.3 0.3 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat YceI PF04264.13 KEZ34702.1 - 2e-42 145.2 0.0 2.3e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 YceI-like domain DDE_Tnp_1 PF01609.21 KEZ34703.1 - 4.9e-07 29.6 0.0 6.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DNA_pol_viral_N PF00242.17 KEZ34703.1 - 0.023 14.2 0.0 0.072 12.6 0.0 1.6 1 1 1 2 2 2 0 DNA polymerase (viral) N-terminal domain MFS_1 PF07690.16 KEZ34704.1 - 1.5e-45 155.6 38.2 1.5e-45 155.6 38.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KEZ34704.1 - 5.5 5.1 13.5 5.5 5.1 0.4 4.0 3 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DDE_3 PF13358.6 KEZ34705.1 - 0.00083 19.1 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Thiolase_C PF02803.18 KEZ34706.1 - 0.0018 17.9 2.3 0.0018 17.9 2.3 1.8 1 1 1 2 2 2 1 Thiolase, C-terminal domain AMP-binding PF00501.28 KEZ34707.1 - 1.1e-92 310.9 0.0 1.3e-92 310.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ34707.1 - 1.5e-21 77.1 2.5 1.5e-21 77.1 2.5 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TPR_MalT PF17874.1 KEZ34708.1 - 3e-30 105.8 10.5 3e-30 105.8 10.5 2.3 3 0 0 3 3 3 1 MalT-like TPR region GerE PF00196.19 KEZ34708.1 - 4.7e-14 51.7 0.0 8.8e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 KEZ34708.1 - 1.1e-10 42.2 2.4 1.1e-10 42.2 2.4 3.7 4 0 0 4 4 4 1 AAA ATPase domain TPR_12 PF13424.6 KEZ34708.1 - 9.6e-07 29.0 17.2 2.9e-05 24.3 7.6 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat HTH_24 PF13412.6 KEZ34708.1 - 3.4e-06 26.5 0.4 8e-06 25.3 0.4 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TPR_10 PF13374.6 KEZ34708.1 - 3.8e-05 23.4 11.2 0.0068 16.2 0.7 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_23 PF13384.6 KEZ34708.1 - 0.00018 21.2 0.0 0.00085 19.0 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain TPR_4 PF07721.14 KEZ34708.1 - 0.00023 21.5 3.5 0.0076 16.8 2.3 8.2 9 0 0 9 9 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ34708.1 - 0.0005 20.5 18.4 0.025 15.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Sigma70_r4_2 PF08281.12 KEZ34708.1 - 0.00073 19.2 0.0 0.0056 16.3 0.0 2.6 3 0 0 3 3 2 1 Sigma-70, region 4 AAA_22 PF13401.6 KEZ34708.1 - 0.00081 19.7 0.0 0.0025 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain HTH_38 PF13936.6 KEZ34708.1 - 0.0079 15.9 0.1 0.022 14.5 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_30 PF13604.6 KEZ34708.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ34708.1 - 0.016 14.8 0.4 0.016 14.8 0.4 2.6 2 1 0 2 2 2 0 AAA domain HTH_Tnp_ISL3 PF13542.6 KEZ34708.1 - 0.03 13.7 1.4 0.58 9.6 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 KEZ34708.1 - 0.032 14.0 3.1 0.49 10.2 0.0 3.7 4 0 0 4 4 3 0 IclR helix-turn-helix domain Crp PF00325.20 KEZ34708.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family TPR_21 PF09976.9 KEZ34708.1 - 0.033 13.9 5.5 3 7.5 0.2 3.0 2 2 1 4 4 3 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KEZ34708.1 - 0.047 14.5 0.8 0.047 14.5 0.8 8.6 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ34708.1 - 0.049 13.5 0.6 3 7.8 0.4 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ34708.1 - 0.051 13.8 1.6 2.2 8.6 0.2 3.1 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KEZ34708.1 - 0.059 13.4 4.8 6.1 7.1 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_40 PF14493.6 KEZ34708.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain DUF2089 PF09862.9 KEZ34708.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) TPR_2 PF07719.17 KEZ34708.1 - 0.26 11.5 15.2 0.25 11.5 0.8 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 KEZ34709.1 - 1.6e-49 167.9 4.8 2.8e-49 167.2 4.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ34709.1 - 3.7e-37 127.4 2.9 4.3e-37 127.2 0.4 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ34709.1 - 3.8e-21 75.1 0.0 6.6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ34709.1 - 2e-20 73.5 4.0 3.9e-20 72.5 4.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_N PF00440.23 KEZ34710.1 - 1.2e-20 73.0 0.2 2.4e-19 68.8 0.1 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KEZ34710.1 - 4.5e-07 30.1 0.0 8.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 KEZ34710.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Acyl_transf_3 PF01757.22 KEZ34711.1 - 3e-14 52.9 29.7 3.9e-14 52.5 29.7 1.1 1 0 0 1 1 1 1 Acyltransferase family US22 PF02393.16 KEZ34711.1 - 0.027 14.8 0.4 0.066 13.5 0.4 1.7 1 0 0 1 1 1 0 US22 like LysR_substrate PF03466.20 KEZ34712.1 - 2e-25 89.4 4.2 2e-25 89.4 4.2 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 KEZ34712.1 - 2.4e-19 69.1 2.9 2.4e-19 69.1 2.9 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 KEZ34712.1 - 0.0024 17.7 0.3 0.0077 16.1 0.3 1.9 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.6 KEZ34712.1 - 0.048 13.5 0.4 0.091 12.6 0.4 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Lactamase_B_2 PF12706.7 KEZ34713.1 - 8e-24 84.3 0.7 1.6e-22 80.0 0.7 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEZ34713.1 - 6.8e-10 39.3 3.1 3.2e-09 37.1 3.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KEZ34713.1 - 7.3e-05 22.7 0.0 0.00051 20.0 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SBP_bac_1 PF01547.25 KEZ34715.1 - 6.1e-36 125.0 10.4 9.5e-36 124.3 10.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KEZ34715.1 - 7.6e-36 124.4 5.7 7.6e-36 124.4 5.7 1.3 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KEZ34715.1 - 0.00064 19.5 11.2 0.0025 17.6 11.2 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KEZ34716.1 - 8.1e-10 38.7 8.3 8.1e-10 38.7 8.3 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KEZ34717.1 - 1.7e-15 57.2 9.0 1.7e-15 57.2 9.0 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KEZ34718.1 - 7.7e-31 107.4 0.0 1.1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ34718.1 - 7.6e-10 39.1 0.2 0.00084 19.2 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ34718.1 - 0.00013 21.5 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KEZ34718.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 KEZ34718.1 - 0.0021 18.6 0.0 0.0028 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ34718.1 - 0.0025 18.1 0.2 0.0095 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ34718.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KEZ34718.1 - 0.008 15.8 0.1 0.095 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ34718.1 - 0.038 14.4 1.4 0.18 12.2 1.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KEZ34718.1 - 0.043 13.5 8.3 0.059 13.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KEZ34718.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 KEZ34718.1 - 0.046 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain OB_MalK PF17912.1 KEZ34718.1 - 0.068 14.0 0.0 0.24 12.2 0.0 2.0 1 0 0 1 1 1 0 MalK OB fold domain AAA_15 PF13175.6 KEZ34718.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KEZ34718.1 - 0.16 12.1 0.3 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Hydrolase PF00702.26 KEZ34719.1 - 0.00012 22.5 0.0 0.00023 21.5 0.0 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ34719.1 - 0.00029 21.0 0.0 0.00039 20.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ34719.1 - 0.00049 20.1 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like AAA_33 PF13671.6 KEZ34720.1 - 5.6e-19 68.7 2.9 2.5e-18 66.6 2.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ34720.1 - 0.00029 21.3 2.6 0.00062 20.2 2.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KEZ34720.1 - 0.022 15.3 0.2 0.055 14.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ34720.1 - 0.065 12.5 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 KEZ34720.1 - 0.067 12.2 0.2 0.12 11.3 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KEZ34720.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KEZ34720.1 - 0.12 12.6 1.7 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEZ34720.1 - 0.18 12.2 0.2 1.3 9.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain Response_reg PF00072.24 KEZ34721.1 - 2.2e-23 82.6 0.0 3.1e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ34721.1 - 5.4e-19 67.5 0.4 8.9e-19 66.8 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ34721.1 - 4.5e-10 39.0 0.9 8.8e-10 38.1 0.4 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ34721.1 - 2.1e-05 23.9 1.0 5.8e-05 22.5 1.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KEZ34721.1 - 4.1e-05 23.2 0.1 0.00011 21.9 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KEZ34721.1 - 0.00026 20.7 0.2 0.00058 19.6 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ34721.1 - 0.00068 19.1 0.3 0.0018 17.8 0.3 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KEZ34721.1 - 0.015 15.3 0.1 0.054 13.5 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_40 PF14493.6 KEZ34721.1 - 0.017 15.5 0.2 0.05 14.1 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 KEZ34721.1 - 0.029 14.3 0.8 0.072 13.1 0.8 1.7 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 KEZ34721.1 - 0.044 13.2 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TadZ_N PF16968.5 KEZ34721.1 - 0.08 12.6 0.9 0.18 11.5 0.5 1.9 1 1 0 1 1 1 0 Pilus assembly protein TadZ N-terminal HTH_Tnp_4 PF13613.6 KEZ34721.1 - 0.092 12.5 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Methyltransf_19 PF04672.12 KEZ34722.1 - 1.6e-53 181.9 0.0 1.8e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Sigma70_r4 PF04545.16 KEZ34723.1 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.7 KEZ34723.1 - 0.091 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Filo_VP35 PF02097.15 KEZ34723.1 - 0.12 11.5 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Filoviridae VP35 Resolvase PF00239.21 KEZ34726.1 - 7.2e-05 22.9 0.1 0.00012 22.3 0.1 1.4 1 1 0 1 1 1 1 Resolvase, N terminal domain VWA_CoxE PF05762.14 KEZ34726.1 - 0.012 15.0 0.9 0.015 14.7 0.9 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein HTH_31 PF13560.6 KEZ34727.1 - 4.1e-12 46.2 4.4 4.1e-12 46.2 4.4 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34727.1 - 4.5e-12 45.8 0.4 9.6e-12 44.8 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ34727.1 - 5.2e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ34727.1 - 0.00013 21.8 0.5 0.00037 20.3 0.5 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ34727.1 - 0.0016 18.2 0.1 0.008 16.0 0.1 2.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_26 PF13443.6 KEZ34727.1 - 0.0018 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TPR_14 PF13428.6 KEZ34727.1 - 0.024 15.4 16.4 2.4 9.2 0.6 5.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 KEZ34727.1 - 0.028 13.9 0.2 0.094 12.3 0.2 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_7 PF13176.6 KEZ34727.1 - 0.032 14.3 1.2 37 4.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_35 PF13693.6 KEZ34727.1 - 0.1 12.7 0.1 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TPR_4 PF07721.14 KEZ34727.1 - 0.15 12.8 0.7 0.15 12.8 0.7 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ34727.1 - 0.18 12.1 7.4 0.1 12.9 0.7 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF397 PF04149.12 KEZ34728.1 - 6e-07 29.4 0.1 8.9e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF397) PIN PF01850.21 KEZ34729.1 - 0.018 15.5 0.0 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 PIN domain EHN PF06441.12 KEZ34730.1 - 2e-31 108.5 0.5 3.9e-31 107.6 0.5 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KEZ34730.1 - 3.2e-08 33.5 1.1 4.7e-08 33.0 0.3 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold PEP_mutase PF13714.6 KEZ34732.1 - 4.7e-69 232.5 0.4 5.4e-69 232.3 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase HTH_1 PF00126.27 KEZ34732.1 - 0.38 10.7 2.5 5.8 7.0 0.2 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family IDH PF03971.14 KEZ34734.1 - 0 1241.7 0.0 0 1241.5 0.0 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DUF2142 PF09913.9 KEZ34735.1 - 3e-111 372.0 9.9 3e-111 372.0 9.9 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2142) DUF4179 PF13786.6 KEZ34736.1 - 0.039 14.4 0.7 0.1 13.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) HxlR PF01638.17 KEZ34738.1 - 2.5e-25 88.1 0.1 3e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 KEZ34738.1 - 0.001 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KEZ34738.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 KEZ34738.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YceI PF04264.13 KEZ34739.1 - 2.1e-45 154.9 0.1 2.4e-45 154.7 0.1 1.0 1 0 0 1 1 1 1 YceI-like domain ChlI PF13541.6 KEZ34739.1 - 0.19 11.6 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Molydop_binding PF01568.21 KEZ34741.1 - 1.6e-09 37.7 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain DUF2079 PF09852.9 KEZ34742.1 - 0.0011 17.9 1.8 0.0011 17.9 1.8 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2079) LIP PF03583.14 KEZ34744.1 - 0.00027 20.4 0.7 0.18 11.1 0.3 2.2 2 0 0 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.8 KEZ34744.1 - 0.0066 15.7 0.2 0.16 11.2 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 PsbQ PF05757.11 KEZ34744.1 - 0.12 12.1 2.2 0.22 11.2 2.2 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Prenyltransf PF01255.19 KEZ34746.1 - 1.9e-70 236.9 0.0 2.1e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1360 PF07098.11 KEZ34748.1 - 4.5e-34 116.5 0.0 6.9e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1360) CxC7 PF18866.1 KEZ34749.1 - 0.025 14.7 2.5 2.6 8.2 0.2 2.8 1 1 1 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases DUF1660 PF07874.11 KEZ34749.1 - 0.2 12.2 1.2 0.46 11.0 1.2 1.6 1 1 0 1 1 1 0 Prophage protein (DUF1660) LCM PF04072.14 KEZ34751.1 - 1.9e-34 119.2 0.0 3e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TetR_N PF00440.23 KEZ34753.1 - 9.5e-09 34.9 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family 4HBT PF03061.22 KEZ34754.1 - 1.2e-16 60.9 0.9 1.7e-16 60.3 0.9 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KEZ34754.1 - 6e-07 29.7 0.0 7.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KEZ34754.1 - 0.0002 21.7 1.0 0.00026 21.3 1.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF222 PF02720.17 KEZ34755.1 - 9.4e-76 255.2 15.3 1.1e-75 254.9 15.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 KEZ34755.1 - 5.5e-05 23.3 5.6 5.5e-05 23.3 5.6 2.1 2 0 0 2 2 2 1 HNH endonuclease Toxin_8 PF07365.12 KEZ34755.1 - 0.83 9.9 5.1 6 7.1 0.8 2.5 2 0 0 2 2 2 0 Alpha conotoxin precursor MFS_1 PF07690.16 KEZ34756.1 - 1.5e-15 57.0 19.3 1.7e-15 56.8 19.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ34756.1 - 0.097 11.5 9.5 0.12 11.2 9.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ34756.1 - 4.1 6.2 7.3 4.5 6.0 7.3 1.1 1 0 0 1 1 1 0 MFS_1 like family GntR PF00392.21 KEZ34758.1 - 7.6e-19 67.1 0.1 1.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family UTRA PF07702.13 KEZ34758.1 - 1.3e-18 67.2 0.0 2.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 UTRA domain HTH_41 PF14502.6 KEZ34758.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 KEZ34758.1 - 0.016 15.0 0.2 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KEZ34758.1 - 0.065 13.6 0.0 0.16 12.3 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator DUF1624 PF07786.12 KEZ34760.1 - 3.9e-10 39.7 7.9 3.9e-10 39.7 7.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) OpgC_C PF10129.9 KEZ34760.1 - 0.00014 20.9 21.6 0.035 13.0 0.4 2.6 1 1 0 2 2 2 2 OpgC protein DUF418 PF04235.12 KEZ34760.1 - 0.002 18.1 4.4 0.002 18.1 4.4 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF418) DUF4213 PF13938.6 KEZ34760.1 - 0.041 14.1 0.5 0.14 12.4 0.5 2.0 1 0 0 1 1 1 0 Putative heavy-metal chelation DUF952 PF06108.12 KEZ34761.1 - 9.9e-25 86.4 0.0 1.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Pterin_4a PF01329.19 KEZ34762.1 - 5.5e-17 61.7 0.0 6.1e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF3750 PF12570.8 KEZ34762.1 - 0.11 13.2 0.0 0.13 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3750) NUDIX PF00293.28 KEZ34763.1 - 4.8e-18 65.5 2.0 6.7e-18 65.0 2.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEZ34763.1 - 3.6e-09 36.6 0.1 4.8e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain GTP_EFTU PF00009.27 KEZ34764.1 - 1e-51 175.3 0.0 1.5e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEZ34764.1 - 7.1e-22 77.2 0.0 1.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEZ34764.1 - 1e-11 45.0 0.1 4.7e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ34764.1 - 5.8e-07 29.6 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KEZ34764.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KEZ34764.1 - 0.057 13.0 0.2 1.4 8.5 0.2 3.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 KEZ34764.1 - 0.22 11.1 0.0 0.5 9.9 0.0 1.7 1 0 0 1 1 1 0 Ras family PIG-L PF02585.17 KEZ34765.1 - 9.1e-22 78.1 0.0 1.3e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Trypsin_2 PF13365.6 KEZ34766.1 - 1.1e-27 97.8 8.6 1.1e-27 97.8 8.6 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 KEZ34766.1 - 6.1e-11 42.0 4.0 6.4e-09 35.5 0.2 2.6 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 KEZ34766.1 - 3.7e-09 36.7 0.1 5.8e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KEZ34766.1 - 5.8e-09 36.2 0.1 1.5e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KEZ34766.1 - 0.0097 16.2 0.0 0.042 14.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KEZ34766.1 - 0.02 14.8 0.4 0.05 13.6 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S32 PF05579.13 KEZ34766.1 - 0.023 13.9 10.3 0.29 10.3 0.7 2.7 2 1 1 3 3 3 0 Equine arteritis virus serine endopeptidase S32 Abhydro_lipase PF04083.16 KEZ34766.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pex14_N PF04695.13 KEZ34767.1 - 0.0093 16.6 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Flavin_Reduct PF01613.18 KEZ34768.1 - 1.1e-31 110.0 0.0 1.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Transglut_core2 PF13369.6 KEZ34769.1 - 3.6e-57 192.3 0.0 5.6e-57 191.7 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 KEZ34769.1 - 1.4e-12 47.5 6.2 1.4e-12 47.5 6.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fer4 PF00037.27 KEZ34770.1 - 6.1e-10 38.5 17.8 3.4e-08 33.0 5.8 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ34770.1 - 3.5e-07 30.7 23.7 0.00029 21.4 4.3 2.3 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ34770.1 - 4.2e-06 27.6 4.5 0.00028 21.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KEZ34770.1 - 1e-05 25.5 6.1 6.8e-05 22.9 0.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ34770.1 - 6.6e-05 22.8 5.0 6.6e-05 22.8 5.0 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 KEZ34770.1 - 0.00026 21.3 2.0 0.00026 21.3 2.0 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KEZ34770.1 - 0.00066 19.8 10.8 0.0016 18.6 10.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ34770.1 - 0.0017 18.8 5.4 0.0023 18.3 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KEZ34770.1 - 0.0024 17.9 3.4 0.0024 17.9 3.4 2.7 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 KEZ34770.1 - 0.0033 17.5 15.9 0.058 13.5 15.9 2.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ34770.1 - 0.028 14.9 2.0 0.028 14.9 2.0 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KEZ34770.1 - 0.11 13.0 10.0 0.15 12.6 1.8 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KEZ34770.1 - 0.27 12.2 17.0 0.24 12.4 7.1 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain Aminotran_1_2 PF00155.21 KEZ34771.1 - 2.5e-41 142.0 0.0 9e-40 136.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Glyoxalase_3 PF13468.6 KEZ34771.1 - 0.038 14.1 0.2 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain Cys_Met_Meta_PP PF01053.20 KEZ34771.1 - 0.21 10.0 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pericardin_rpt PF07054.11 KEZ34771.1 - 1.2 9.3 10.8 0.29 11.3 1.9 2.5 2 1 1 3 3 3 0 Pericardin like repeat THDPS_N_2 PF14805.6 KEZ34772.1 - 4.9e-16 58.7 0.1 7.6e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep PF00132.24 KEZ34772.1 - 1.7e-10 40.1 8.1 0.00082 19.0 1.7 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ34772.1 - 3.4e-07 29.9 3.7 6.3e-06 25.8 0.1 3.4 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Peptidase_M20 PF01546.28 KEZ34773.1 - 1.1e-22 80.8 0.2 1.6e-22 80.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ34773.1 - 5.9e-13 48.7 0.0 2e-12 47.0 0.0 1.9 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ34773.1 - 0.00021 21.0 0.0 0.0095 15.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 Bac_transf PF02397.16 KEZ34774.1 - 2e-59 200.3 0.0 3.4e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 KEZ34774.1 - 4.6e-13 49.5 0.2 7.8e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 CoA-binding domain Glycos_transf_2 PF00535.26 KEZ34776.1 - 1.3e-14 54.3 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ34776.1 - 2.3e-06 27.7 0.0 3.2e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ34776.1 - 0.004 16.6 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_1_4 PF13692.6 KEZ34777.1 - 2.3e-21 76.7 0.0 5.2e-21 75.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ34777.1 - 2.4e-21 76.5 2.1 2.4e-21 76.5 2.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEZ34777.1 - 2.8e-21 75.8 0.0 1.4e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ34777.1 - 3.6e-15 56.8 6.2 3.6e-15 56.8 6.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ34777.1 - 2.1e-11 44.1 0.0 4.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ34777.1 - 6.7e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KEZ34777.1 - 0.0005 19.8 1.3 0.011 15.4 1.3 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain ETF PF01012.21 KEZ34777.1 - 0.038 13.9 0.2 0.1 12.5 0.2 1.7 1 1 0 1 1 1 0 Electron transfer flavoprotein domain 2TM PF13239.6 KEZ34779.1 - 0.72 10.2 2.2 1.7 9.0 2.2 1.8 1 1 0 1 1 1 0 2TM domain Glyco_transf_4 PF13439.6 KEZ34780.1 - 3e-25 89.2 1.7 5.5e-25 88.3 1.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEZ34780.1 - 5.9e-21 74.8 0.0 1.8e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ34780.1 - 1e-20 74.8 4.7 1e-20 74.8 4.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KEZ34780.1 - 8.5e-19 68.3 0.5 3.2e-18 66.5 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ34780.1 - 5.8e-05 23.1 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF3772 PF12607.8 KEZ34781.1 - 0.061 13.1 0.5 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Glycos_transf_2 PF00535.26 KEZ34782.1 - 1.3e-20 73.9 0.0 2.9e-20 72.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ34782.1 - 5.4e-14 52.6 0.5 4.1e-13 49.8 0.5 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ34782.1 - 3.6e-09 36.3 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KEZ34782.1 - 7e-07 29.3 0.3 1e-06 28.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 GMC_oxred_C PF05199.13 KEZ34783.1 - 0.00012 22.6 0.1 0.00024 21.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Fer4_10 PF13237.6 KEZ34783.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 KEZ34783.1 - 0.0028 16.9 0.0 0.21 10.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_8 PF13183.6 KEZ34783.1 - 0.0059 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KEZ34783.1 - 0.01 15.6 2.9 0.016 15.0 2.9 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ34783.1 - 0.014 16.0 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ34783.1 - 0.018 15.2 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ34783.1 - 0.044 14.3 0.1 0.081 13.5 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KEZ34783.1 - 0.074 13.2 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEZ34783.1 - 0.086 13.4 1.8 0.16 12.5 1.8 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain GMC_oxred_N PF00732.19 KEZ34783.1 - 0.15 11.4 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Fer4_16 PF13484.6 KEZ34783.1 - 0.16 12.9 0.1 0.28 12.2 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KEZ34783.1 - 0.32 11.1 3.7 0.59 10.3 3.7 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ34783.1 - 0.41 10.8 4.3 0.75 10.0 4.3 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 KEZ34783.1 - 4.5 8.4 5.4 7.9 7.7 5.4 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Epimerase PF01370.21 KEZ34784.1 - 3.8e-06 26.6 0.0 1.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ34784.1 - 0.00035 19.8 0.0 0.0065 15.6 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KEZ34784.1 - 0.0019 17.8 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KEZ34784.1 - 0.0048 16.8 0.1 0.13 12.2 0.1 2.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEZ34784.1 - 0.0072 15.5 0.1 0.69 9.0 0.0 2.8 1 1 2 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.19 KEZ34784.1 - 0.07 12.1 0.0 0.46 9.4 0.0 2.1 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family DDE_Tnp_1 PF01609.21 KEZ34785.1 - 1.8e-05 24.5 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_assoc PF13808.6 KEZ34786.1 - 4.2e-17 61.9 0.0 9.9e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ34786.1 - 7.8e-16 58.4 0.1 9.8e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ34788.1 - 2.6e-23 82.8 5.7 8.7e-22 77.8 5.7 2.1 1 1 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 KEZ34788.1 - 8.8e-22 77.1 4.5 8.8e-22 77.1 4.5 2.1 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 KEZ34788.1 - 2.2e-11 44.0 0.5 4e-11 43.1 0.5 1.5 1 0 0 1 1 1 1 Transposase DDE domain Methyltransf_9 PF08003.11 KEZ34788.1 - 0.0037 16.2 0.1 0.0051 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) rve PF00665.26 KEZ34788.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_4 PF13359.6 KEZ34788.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 KEZ34788.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.9 2 1 0 2 2 2 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KEZ34789.1 - 2e-09 37.7 0.0 2.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain NPV_P10 PF05531.12 KEZ34792.1 - 0.0048 17.3 1.5 0.22 12.0 0.0 3.2 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Phage_attach PF05354.11 KEZ34792.1 - 0.055 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Phage Head-Tail Attachment AAA_21 PF13304.6 KEZ34792.1 - 0.091 12.6 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ34792.1 - 0.15 11.5 0.0 3.6 7.0 0.0 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain CorA PF01544.18 KEZ34792.1 - 8.9 5.5 6.3 9.4 5.4 2.9 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MarR_2 PF12802.7 KEZ34793.1 - 1.9e-06 27.6 0.7 0.00019 21.3 0.3 3.6 3 0 0 3 3 3 1 MarR family Rrf2 PF02082.20 KEZ34793.1 - 0.00011 22.4 0.0 0.00072 19.9 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator DprA_WH PF17782.1 KEZ34793.1 - 0.00045 20.3 0.2 0.0043 17.1 0.0 2.8 2 1 0 2 2 2 1 DprA winged helix domain HTH_Crp_2 PF13545.6 KEZ34793.1 - 0.0016 18.3 0.0 0.021 14.8 0.0 2.5 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain GntR PF00392.21 KEZ34793.1 - 0.0066 16.1 0.2 1.1 9.0 0.0 3.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 KEZ34793.1 - 0.011 15.7 0.0 0.55 10.2 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain TrmB PF01978.19 KEZ34793.1 - 0.012 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HrcA_DNA-bdg PF03444.15 KEZ34793.1 - 0.021 14.5 0.1 0.32 10.7 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_IclR PF09339.10 KEZ34793.1 - 0.03 14.1 0.1 0.083 12.7 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_5 PF01022.20 KEZ34793.1 - 0.067 13.1 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR PF01047.22 KEZ34793.1 - 0.15 12.0 0.0 7.2 6.6 0.0 2.6 2 0 0 2 2 2 0 MarR family HTH_CodY PF08222.11 KEZ34793.1 - 0.15 11.7 0.0 12 5.5 0.0 2.9 3 0 0 3 3 3 0 CodY helix-turn-helix domain HTH_46 PF15977.5 KEZ34793.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding SMC_ScpB PF04079.16 KEZ34794.1 - 0.15 11.6 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB DUF2220 PF09983.9 KEZ34795.1 - 5.9e-13 48.6 0.0 8.6e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF2399 PF09664.10 KEZ34795.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) PCMT PF01135.19 KEZ34797.1 - 1.1e-33 116.8 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KEZ34797.1 - 9.6e-08 33.0 0.2 2.7e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34797.1 - 6.2e-06 26.1 0.0 9.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ34797.1 - 4e-05 24.3 0.0 7.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEZ34797.1 - 6.7e-05 22.2 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase ADH_zinc_N PF00107.26 KEZ34797.1 - 0.00079 19.4 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KEZ34797.1 - 0.0011 19.5 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_19 PF04672.12 KEZ34797.1 - 0.0013 18.3 0.1 0.002 17.7 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl methyltransferase GCD14 PF08704.10 KEZ34797.1 - 0.0042 16.8 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KEZ34797.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEZ34797.1 - 0.015 14.7 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.17 KEZ34797.1 - 0.1 11.7 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Fibrillarin Lant_dehydr_N PF04738.13 KEZ34799.1 - 9.5e-205 681.5 32.8 1.5e-204 680.9 32.8 1.3 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus Lant_dehydr_C PF14028.6 KEZ34799.1 - 0.073 12.6 15.2 0.012 15.1 6.3 3.4 3 1 0 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term AP_endonuc_2 PF01261.24 KEZ34799.1 - 0.086 12.3 0.4 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel LANC_like PF05147.13 KEZ34800.1 - 5.4e-42 143.6 0.0 6.2e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Lant_dehydr_C PF14028.6 KEZ34801.1 - 3.4e-38 131.9 0.3 5.4e-38 131.3 0.3 1.3 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term adh_short_C2 PF13561.6 KEZ34803.1 - 1.2e-51 175.6 0.0 1.5e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ34803.1 - 1.6e-45 154.9 0.0 2.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ34803.1 - 2e-07 31.1 0.2 2.9e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEZ34803.1 - 1.6e-06 28.2 0.3 2.8e-06 27.3 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KEZ34803.1 - 6.3e-05 22.5 0.1 0.0089 15.5 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ34803.1 - 0.0096 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HTH_31 PF13560.6 KEZ34804.1 - 4.5e-06 26.9 0.7 3.3e-05 24.1 0.7 2.7 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_2 PF07719.17 KEZ34804.1 - 5.1e-06 26.2 5.5 4.1 7.7 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ34804.1 - 0.00057 20.1 8.8 0.18 12.1 1.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ34804.1 - 0.022 14.1 11.6 0.026 13.9 0.2 3.3 3 1 0 3 3 3 0 MalT-like TPR region TPR_14 PF13428.6 KEZ34804.1 - 0.045 14.6 20.6 5.8 8.0 0.5 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat HTH_3 PF01381.22 KEZ34804.1 - 0.15 12.1 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix TPR_8 PF13181.6 KEZ34804.1 - 0.16 12.2 2.8 36 4.9 0.0 4.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ34804.1 - 1.8 9.3 4.9 37 5.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Mrr_cat PF04471.12 KEZ34805.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease DUF397 PF04149.12 KEZ34806.1 - 6.9e-28 96.5 0.1 7.8e-28 96.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KEZ34807.1 - 4.7e-14 52.5 1.0 1.3e-13 51.1 1.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KEZ34807.1 - 0.00056 19.8 0.0 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34807.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 KEZ34807.1 - 0.064 13.1 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain CbtA PF09490.10 KEZ34808.1 - 0.15 11.8 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) HATPase_c_2 PF13581.6 KEZ34809.1 - 3.8e-06 26.9 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DDE_Tnp_1_assoc PF13808.6 KEZ34810.1 - 1.5e-15 57.0 0.1 7e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ34810.1 - 1.8e-10 40.9 0.1 2.9e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 KEZ34811.1 - 4.7e-16 58.3 0.0 7e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4_2 PF08281.12 KEZ34811.1 - 0.00046 19.8 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 DDE_Tnp_4 PF13359.6 KEZ34811.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4 PF04545.16 KEZ34811.1 - 0.0052 16.3 0.1 0.0099 15.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 KEZ34811.1 - 0.0095 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DDE_Tnp_1 PF01609.21 KEZ34811.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HTH_11 PF08279.12 KEZ34811.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 HTH domain CLP_protease PF00574.23 KEZ34812.1 - 3.5e-72 242.1 0.1 4.3e-72 241.8 0.1 1.0 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 KEZ34812.1 - 0.093 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 CLP_protease PF00574.23 KEZ34813.1 - 2.5e-76 255.7 0.4 3.3e-76 255.2 0.1 1.3 2 0 0 2 2 2 1 Clp protease HTH_31 PF13560.6 KEZ34814.1 - 5.7e-10 39.4 8.3 1.3e-09 38.3 5.7 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34814.1 - 1.1e-09 38.1 0.1 1.8e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 KEZ34814.1 - 9.6e-06 25.4 0.6 1.7e-05 24.6 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ34814.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ34814.1 - 0.059 13.8 0.1 0.092 13.2 0.1 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Collagen PF01391.18 KEZ34815.1 - 0.013 15.2 4.2 0.024 14.4 4.2 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HpaB_N PF11794.8 KEZ34816.1 - 3.3e-85 286.0 0.0 4.1e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 KEZ34816.1 - 5.1e-38 130.2 0.0 7.2e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Acyl-CoA_dh_M PF02770.19 KEZ34816.1 - 0.024 14.8 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain GerE PF00196.19 KEZ34817.1 - 9.7e-13 47.5 0.0 1.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ34817.1 - 7.5e-05 22.3 0.2 0.00015 21.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 KEZ34817.1 - 0.029 14.2 0.1 0.076 12.8 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_38 PF13936.6 KEZ34817.1 - 0.041 13.7 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 KEZ34817.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor Sigma70_r4 PF04545.16 KEZ34817.1 - 0.12 11.9 0.2 0.29 10.7 0.2 1.7 1 1 0 1 1 1 0 Sigma-70, region 4 MLTR_LBD PF17765.1 KEZ34818.1 - 1.7e-35 122.7 5.5 3.1e-35 121.8 5.5 1.5 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KEZ34818.1 - 8.2e-17 61.3 9.6 3.8e-16 59.2 9.6 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain PAS_8 PF13188.7 KEZ34818.1 - 0.038 14.0 0.3 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 PAS domain SBP_bac_5 PF00496.22 KEZ34821.1 - 8.3e-85 285.0 5.7 1e-84 284.7 5.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle ATP-synt_J PF04911.12 KEZ34821.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 ATP synthase j chain BPD_transp_1 PF00528.22 KEZ34822.1 - 1e-23 84.0 15.0 1e-23 84.0 15.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KEZ34823.1 - 4.1e-19 69.0 13.8 4.1e-19 69.0 13.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KEZ34824.1 - 1.1e-53 181.5 0.0 3.6e-30 105.2 0.0 2.2 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 KEZ34824.1 - 2.9e-13 50.1 0.1 9e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KEZ34824.1 - 1.7e-11 44.5 6.8 0.0018 18.1 0.1 4.1 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEZ34824.1 - 5.8e-06 26.6 8.6 0.043 14.1 0.5 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ34824.1 - 9.4e-05 22.1 1.1 0.32 10.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ34824.1 - 0.0001 22.8 11.4 0.005 17.2 1.3 2.9 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KEZ34824.1 - 0.00016 21.4 0.2 0.044 13.5 0.1 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KEZ34824.1 - 0.00034 20.6 0.2 0.2 11.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 KEZ34824.1 - 0.00035 20.5 1.4 0.42 10.5 0.1 2.6 2 0 0 2 2 2 2 NACHT domain Sigma54_activat PF00158.26 KEZ34824.1 - 0.00062 19.5 0.4 0.86 9.3 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 KEZ34824.1 - 0.0013 18.7 1.8 0.53 10.3 0.2 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SMC_N PF02463.19 KEZ34824.1 - 0.0026 17.2 0.1 10 5.5 0.0 3.7 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KEZ34824.1 - 0.0031 16.9 0.3 2.8 7.3 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 KEZ34824.1 - 0.0053 17.2 0.5 4.8 7.6 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEZ34824.1 - 0.0062 16.3 1.0 0.71 9.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KEZ34824.1 - 0.0067 16.4 0.8 1.9 8.5 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEZ34824.1 - 0.0087 16.2 4.2 1.5 9.0 0.1 3.0 3 1 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KEZ34824.1 - 0.016 14.7 0.4 3.7 7.0 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KEZ34824.1 - 0.017 14.7 4.0 0.88 9.1 0.7 2.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEZ34824.1 - 0.02 15.0 0.5 5.2 7.2 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KEZ34824.1 - 0.052 14.1 0.8 17 5.9 0.3 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEZ34824.1 - 0.058 13.5 3.9 2.2 8.3 0.4 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KEZ34824.1 - 0.073 13.6 0.0 3.6 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEZ34824.1 - 0.088 12.0 2.0 1.7 7.7 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KEZ34824.1 - 0.14 12.0 0.6 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KEZ34824.1 - 0.15 12.5 0.6 23 5.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KEZ34824.1 - 0.18 11.2 0.8 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 KEZ34824.1 - 0.18 11.9 0.2 21 5.2 0.1 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.14 KEZ34824.1 - 0.24 11.3 0.5 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 KEZ34824.1 - 0.34 11.1 1.0 8.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 KEZ34824.1 - 0.34 10.6 2.1 8.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 KEZ34824.1 - 0.81 9.4 5.7 15 5.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 KEZ34824.1 - 1.4 8.3 2.1 16 4.8 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 KEZ34824.1 - 2 7.6 4.0 14 4.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Methyltransf_25 PF13649.6 KEZ34825.1 - 5.7e-14 52.6 0.0 4.3e-13 49.8 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ34825.1 - 4e-12 46.6 0.0 1.6e-11 44.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34825.1 - 2.8e-11 44.0 0.0 5.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34825.1 - 5.9e-10 39.1 0.0 9.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34825.1 - 6.2e-10 39.2 0.0 1.9e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEZ34825.1 - 0.00059 19.4 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ34825.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEZ34825.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 KEZ34825.1 - 0.052 13.1 0.0 0.084 12.5 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW AHSA1 PF08327.11 KEZ34825.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Methyltransf_5 PF01795.19 KEZ34825.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family FtsJ PF01728.19 KEZ34825.1 - 0.15 12.1 0.0 0.53 10.4 0.0 2.2 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KEZ34826.1 - 4.9e-17 62.4 0.0 8.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34826.1 - 3.3e-16 59.9 0.0 1.8e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ34826.1 - 8.2e-16 58.5 0.0 1.7e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34826.1 - 9.1e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34826.1 - 5.9e-11 42.4 0.0 1.4e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ34826.1 - 6.2e-05 22.4 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ34826.1 - 7.7e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KEZ34826.1 - 0.0083 15.6 0.0 0.046 13.2 0.0 1.9 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 KEZ34826.1 - 0.045 13.5 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_17 PF12692.7 KEZ34826.1 - 0.09 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DREV PF05219.12 KEZ34826.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 KEZ34826.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 KEZ34826.1 - 0.13 13.3 0.1 0.36 11.9 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KEZ34826.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Bac_luciferase PF00296.20 KEZ34827.1 - 2.8e-56 191.3 1.7 3.3e-56 191.0 1.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Usp PF00582.26 KEZ34828.1 - 1.2e-48 165.2 13.8 1.9e-25 90.0 1.8 2.2 2 0 0 2 2 2 2 Universal stress protein family Abhydrolase_3 PF07859.13 KEZ34829.1 - 2.3e-21 76.6 2.2 4e-21 75.9 2.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ34829.1 - 4.9e-14 52.3 0.1 7.6e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KEZ34829.1 - 2.8e-09 36.4 0.2 5.8e-09 35.4 0.2 1.3 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KEZ34829.1 - 0.00061 19.4 0.1 0.073 12.6 0.0 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Esterase_phd PF10503.9 KEZ34829.1 - 0.011 15.3 2.0 0.47 9.9 0.5 2.6 2 1 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KEZ34829.1 - 0.051 12.8 0.3 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KEZ34829.1 - 0.085 12.7 0.0 12 5.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TetR_C_11 PF16859.5 KEZ34831.1 - 1.6e-26 92.9 1.1 1.6e-26 92.9 1.1 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ34831.1 - 7.1e-14 51.3 0.1 1.1e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 KEZ34831.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TetR_C_25 PF17933.1 KEZ34831.1 - 0.091 13.1 0.0 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 KEZ34832.1 - 9.8e-49 166.1 44.8 9.8e-49 166.1 44.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ34832.1 - 2.8e-05 23.2 8.4 2.8e-05 23.2 8.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Trp_halogenase PF04820.14 KEZ34833.1 - 1.2e-23 83.7 0.8 6e-15 55.1 0.2 2.8 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KEZ34833.1 - 1.7e-07 30.8 0.0 7.3e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ34833.1 - 5.7e-07 29.0 0.1 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ34833.1 - 3.8e-05 23.2 0.2 6.7e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ34833.1 - 5.7e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KEZ34833.1 - 9.3e-05 22.6 0.1 0.00073 19.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ34833.1 - 0.00084 18.5 0.0 0.076 12.1 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KEZ34833.1 - 0.00091 18.9 4.9 0.017 14.7 0.0 3.1 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ34833.1 - 0.0014 17.8 0.8 0.0026 16.9 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ34833.1 - 0.0015 17.3 0.0 0.05 12.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KEZ34833.1 - 0.055 13.5 0.2 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEZ34833.1 - 0.12 13.0 0.0 15 6.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TauD PF02668.16 KEZ34834.1 - 2e-29 103.2 0.3 2.4e-29 103.0 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEZ34834.1 - 0.009 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 CsiD DIT1_PvcA PF05141.12 KEZ34835.1 - 1.3e-76 257.8 0.0 2.5e-76 256.8 0.0 1.4 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Rhodanese PF00581.20 KEZ34836.1 - 4.5e-11 43.2 0.0 5.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 KEZ34837.1 - 1e-45 156.2 68.2 4.3e-40 137.7 42.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ndr PF03096.14 KEZ34837.1 - 0.22 10.2 0.1 0.37 9.5 0.1 1.2 1 0 0 1 1 1 0 Ndr family HxlR PF01638.17 KEZ34838.1 - 9.7e-24 83.0 0.0 1.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 KEZ34838.1 - 0.00016 21.5 0.7 0.00034 20.5 0.4 1.8 2 1 0 2 2 2 1 MarR family PadR PF03551.14 KEZ34838.1 - 0.00074 19.4 0.2 0.0012 18.8 0.2 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 KEZ34838.1 - 0.0021 17.9 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 KEZ34838.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.6 KEZ34838.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Herpes_UL56 PF04534.12 KEZ34839.1 - 0.021 14.3 3.9 0.029 13.9 3.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF3040 PF11239.8 KEZ34839.1 - 0.077 13.3 5.1 1.4 9.2 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) COX6C PF02937.15 KEZ34839.1 - 0.11 12.7 0.2 22 5.3 0.0 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF2628 PF10947.8 KEZ34839.1 - 0.21 11.9 0.1 0.21 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DEC-1_N PF04625.13 KEZ34840.1 - 0.019 14.0 6.7 0.022 13.8 6.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Med3 PF11593.8 KEZ34840.1 - 0.09 12.0 5.0 0.1 11.8 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_31 PF13614.6 KEZ34841.1 - 4.3e-35 121.2 0.0 6.8e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ34841.1 - 7.2e-16 58.4 0.0 1.3e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KEZ34841.1 - 9.3e-13 48.2 0.0 4e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KEZ34841.1 - 2e-08 33.8 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase MipZ PF09140.11 KEZ34841.1 - 4.7e-07 29.4 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 KEZ34841.1 - 5.9e-07 29.2 0.7 6.9e-06 25.7 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KEZ34841.1 - 2.7e-05 23.7 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 KEZ34841.1 - 0.0002 20.8 0.0 0.0084 15.4 0.0 2.2 2 0 0 2 2 2 1 VirC1 protein MeaB PF03308.16 KEZ34841.1 - 0.0071 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KEZ34841.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KEZ34841.1 - 0.028 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KEZ34841.1 - 0.16 12.3 0.8 17 5.8 0.2 2.4 2 2 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 KEZ34841.1 - 0.25 11.1 0.0 0.56 9.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2397 PF09660.10 KEZ34843.1 - 0.0021 17.1 0.1 0.01 14.8 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2397) Methyltransf_25 PF13649.6 KEZ34844.1 - 9.5e-19 67.9 0.0 1.5e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ34844.1 - 8.4e-18 64.8 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34844.1 - 3.1e-13 49.9 0.0 4.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34844.1 - 3.2e-12 46.5 0.0 5.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34844.1 - 5.4e-08 33.5 0.0 8.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ34844.1 - 3.5e-07 29.8 0.0 4.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KEZ34844.1 - 0.0002 20.4 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KEZ34844.1 - 0.00028 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ34844.1 - 0.00061 19.1 0.0 0.00084 18.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 KEZ34844.1 - 0.0014 18.3 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 KEZ34844.1 - 0.0029 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Resolvase PF00239.21 KEZ34845.1 - 4.7e-20 72.2 2.2 8.4e-20 71.4 2.2 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 KEZ34845.1 - 9.6e-15 54.9 0.0 2.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 KEZ34845.1 - 4.5e-06 27.1 0.8 7.9e-06 26.3 0.8 1.4 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain zf-RRN7 PF11781.8 KEZ34845.1 - 0.76 9.5 3.2 0.73 9.6 0.1 2.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Methyltransf_19 PF04672.12 KEZ34847.1 - 4.6e-48 164.0 0.1 5.3e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Cleaved_Adhesin PF07675.11 KEZ34849.1 - 0.0066 16.4 0.2 2.4 8.1 0.0 2.8 1 1 2 3 3 3 2 Cleaved Adhesin Domain N6_Mtase PF02384.16 KEZ34852.1 - 0.25 10.6 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 N-6 DNA Methylase Helicase_C PF00271.31 KEZ34853.1 - 1.8e-16 60.5 0.0 1.5e-15 57.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEZ34853.1 - 5.1e-09 35.3 0.0 1.2e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEZ34853.1 - 0.00017 21.7 0.0 0.0005 20.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ34853.1 - 0.03 14.1 0.0 0.096 12.4 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase ZapB PF06005.12 KEZ34853.1 - 0.1 13.1 0.6 0.27 11.7 0.6 1.7 1 0 0 1 1 1 0 Cell division protein ZapB ADH_zinc_N PF00107.26 KEZ34854.1 - 1e-12 48.2 1.5 1.9e-12 47.3 1.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ34854.1 - 5.2e-09 37.3 0.3 1.2e-08 36.1 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ34854.1 - 8.8e-09 35.2 0.0 1.2e-06 28.3 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KEZ34854.1 - 0.0018 17.7 0.1 0.03 13.7 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_Tnp_1 PF01527.20 KEZ34856.1 - 1.1e-11 44.9 0.2 1.6e-11 44.4 0.2 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 KEZ34856.1 - 5.3e-05 22.6 0.0 8.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KEZ34856.1 - 0.014 15.2 0.1 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KEZ34856.1 - 0.017 15.2 0.4 0.028 14.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KEZ34856.1 - 0.028 15.0 0.1 0.032 14.7 0.1 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Terminase_5 PF06056.12 KEZ34856.1 - 0.042 13.7 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) MttA_Hcf106 PF02416.16 KEZ34856.1 - 0.12 11.8 0.2 0.43 9.9 0.0 1.9 1 1 1 2 2 2 0 mttA/Hcf106 family YdaS_antitoxin PF15943.5 KEZ34856.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.7 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CENP-B_N PF04218.13 KEZ34856.1 - 0.18 11.4 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_1_2 PF13022.6 KEZ34856.1 - 0.19 11.9 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_31 PF13560.6 KEZ34857.1 - 1.2e-10 41.5 1.0 1.9e-10 40.9 1.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34857.1 - 1.6e-08 34.5 0.1 2.4e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ34857.1 - 8.8e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ34857.1 - 0.00071 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 KEZ34857.1 - 0.014 15.6 0.2 0.15 12.3 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ34857.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 KEZ34857.1 - 0.031 14.0 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 MerR family regulatory protein HTH_26 PF13443.6 KEZ34857.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HipA_C PF07804.12 KEZ34858.1 - 4.1e-46 157.3 0.0 7.4e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 KEZ34858.1 - 7.2e-08 33.0 0.1 1.7e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 HipA N-terminal domain Collagen PF01391.18 KEZ34859.1 - 4.9e-05 23.0 4.4 0.00014 21.6 4.4 1.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) PhoR PF11808.8 KEZ34861.1 - 0.067 13.6 4.9 0.11 12.9 4.9 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR cNMP_binding PF00027.29 KEZ34864.1 - 2e-17 63.0 0.0 3.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 KEZ34864.1 - 1.4e-09 37.8 0.2 3.2e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KEZ34864.1 - 0.0035 17.4 1.1 0.0065 16.5 0.3 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ34864.1 - 0.0055 16.2 0.1 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KEZ34864.1 - 0.0069 16.2 1.7 0.018 14.8 1.5 1.9 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_28 PF13518.6 KEZ34864.1 - 0.031 14.4 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 KEZ34864.1 - 0.042 14.3 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 KEZ34864.1 - 0.12 12.2 5.4 0.27 11.2 0.7 3.0 2 2 1 3 3 3 0 MarR family HTH_AsnC-type PF13404.6 KEZ34864.1 - 0.68 9.8 0.1 0.68 9.8 0.1 2.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain RicinB_lectin_2 PF14200.6 KEZ34865.1 - 0.00023 21.8 0.0 0.0014 19.3 0.0 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 KEZ34865.1 - 0.00097 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I66 Esterase PF00756.20 KEZ34867.1 - 5.2e-16 59.1 0.0 1.3e-15 57.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KEZ34867.1 - 0.0052 16.1 0.1 0.0098 15.2 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ34867.1 - 0.022 14.4 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KEZ34867.1 - 0.22 11.3 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2156 PF09924.9 KEZ34868.1 - 2.6e-108 361.6 0.0 4.1e-108 360.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2_TM PF16995.5 KEZ34868.1 - 4.3e-09 36.4 12.6 8.7e-09 35.4 12.6 1.5 1 1 0 1 1 1 1 Transmembrane region of lysyl-tRNA synthetase DUF1772 PF08592.11 KEZ34868.1 - 0.34 11.2 4.6 14 6.0 1.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) PrsW-protease PF13367.6 KEZ34868.1 - 0.5 9.8 4.1 0.22 11.0 0.9 2.0 2 1 0 2 2 2 0 PrsW family intramembrane metalloprotease DUF998 PF06197.13 KEZ34868.1 - 0.83 9.2 20.5 3.5 7.2 15.9 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) HTH_32 PF13565.6 KEZ34868.1 - 1.3 9.7 0.0 1.3 9.7 0.0 3.4 4 0 0 4 4 4 0 Homeodomain-like domain MerC PF03203.14 KEZ34868.1 - 5.2 7.6 7.0 39 4.8 7.1 2.6 1 1 0 1 1 1 0 MerC mercury resistance protein SfLAP PF11139.8 KEZ34871.1 - 1.7e-39 135.5 22.6 1.9e-39 135.3 22.6 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein SYS1 PF09801.9 KEZ34871.1 - 0.086 13.0 4.0 0.1 12.7 0.7 2.3 1 1 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Cytochrom_B_C PF00032.17 KEZ34871.1 - 1.6 9.0 8.4 7.3 6.9 3.7 2.9 1 1 2 3 3 3 0 Cytochrome b(C-terminal)/b6/petD DDE_Tnp_1 PF01609.21 KEZ34872.1 - 2.7e-05 23.9 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Sigma70_r4_2 PF08281.12 KEZ34873.1 - 2.6e-11 43.0 0.0 4.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KEZ34873.1 - 2.7e-11 43.1 2.0 2.7e-11 43.1 2.0 2.3 2 1 1 3 3 3 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KEZ34873.1 - 4.4e-08 32.5 0.0 1.1e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 SnoaL_2 PF12680.7 KEZ34873.1 - 0.00077 20.1 5.5 0.0011 19.5 0.2 2.5 1 1 1 2 2 2 1 SnoaL-like domain NAD_binding_10 PF13460.6 KEZ34874.1 - 2.6e-15 56.8 2.6 2.6e-15 56.8 2.6 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KEZ34874.1 - 3.1e-12 46.5 0.0 1.4e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ34874.1 - 6.9e-11 42.1 0.2 1.1e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KEZ34874.1 - 9.2e-07 28.2 0.3 1.2e-06 27.8 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEZ34874.1 - 6.6e-06 25.3 0.0 8.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ34874.1 - 7.4e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KEZ34874.1 - 0.00023 21.4 0.2 0.00073 19.8 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEZ34874.1 - 0.0018 18.5 0.3 0.0038 17.5 0.3 1.7 1 1 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KEZ34874.1 - 0.0066 15.9 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KEZ34874.1 - 0.019 14.3 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 KEZ34874.1 - 0.021 14.9 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KEZ34874.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HhH-GPD PF00730.25 KEZ34875.1 - 6.6e-13 49.1 0.0 8.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GGDEF PF00990.21 KEZ34878.1 - 3.9e-39 134.0 0.0 6.1e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 KEZ34878.1 - 0.06 13.7 3.1 0.35 11.2 0.6 3.0 2 2 0 2 2 2 0 GAF domain HTH_8 PF02954.19 KEZ34879.1 - 1.9e-12 46.8 1.0 4.9e-12 45.4 1.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 KEZ34879.1 - 3.9e-07 29.6 0.2 8.4e-07 28.5 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 KEZ34879.1 - 8.4e-06 26.3 0.3 5.6e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain HTH_28 PF13518.6 KEZ34879.1 - 6.7e-05 22.9 0.3 0.0003 20.9 0.3 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 KEZ34879.1 - 0.0003 20.5 0.3 0.00091 19.0 0.3 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA PF00004.29 KEZ34879.1 - 0.00052 20.4 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KEZ34879.1 - 0.00084 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 KEZ34879.1 - 0.0067 16.4 0.0 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.26 KEZ34879.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_23 PF13384.6 KEZ34879.1 - 0.0086 15.9 0.1 0.028 14.2 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain ABC_tran PF00005.27 KEZ34879.1 - 0.01 16.4 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KEZ34879.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KEZ34879.1 - 0.02 15.2 0.2 0.2 11.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KEZ34879.1 - 0.026 14.3 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KEZ34879.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HTH_AsnC-type PF13404.6 KEZ34879.1 - 0.041 13.7 0.3 0.13 12.1 0.3 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_22 PF13309.6 KEZ34879.1 - 0.043 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain AAA_33 PF13671.6 KEZ34879.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain HTH_1 PF00126.27 KEZ34879.1 - 0.052 13.5 0.1 0.39 10.7 0.1 2.4 3 0 0 3 3 2 0 Bacterial regulatory helix-turn-helix protein, lysR family TIP49 PF06068.13 KEZ34879.1 - 0.053 12.7 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Phage_NinH PF06322.11 KEZ34879.1 - 0.055 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Phage NinH protein HTH_29 PF13551.6 KEZ34879.1 - 0.06 13.4 0.2 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn helix AAA_19 PF13245.6 KEZ34879.1 - 0.18 12.2 0.0 12 6.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KEZ34879.1 - 0.24 10.5 0.0 0.42 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain HTH_11 PF08279.12 KEZ34879.1 - 1.1 9.3 3.0 0.59 10.1 0.1 2.1 3 0 0 3 3 2 0 HTH domain Phenol_Hydrox PF02332.18 KEZ34880.1 - 1.6e-56 191.5 0.1 2.4e-56 190.9 0.1 1.3 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase SpoVG PF04026.12 KEZ34880.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 SpoVG FAD_binding_6 PF00970.24 KEZ34881.1 - 3.7e-17 62.5 0.0 6.2e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEZ34881.1 - 1.5e-16 61.0 0.0 6.5e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 KEZ34881.1 - 6.2e-11 42.1 0.1 1.1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 KEZ34881.1 - 0.0013 18.9 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_4 PF13510.6 KEZ34881.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Phenol_Hydrox PF02332.18 KEZ34882.1 - 7.8e-59 199.0 1.9 1e-58 198.6 1.9 1.2 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase MmoB_DmpM PF02406.17 KEZ34883.1 - 1.2e-26 92.7 0.1 1.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 MmoB/DmpM family Amidohydro_2 PF04909.14 KEZ34884.1 - 6.9e-41 140.9 0.7 8.3e-41 140.7 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase FeS_assembly_P PF01883.19 KEZ34885.1 - 1.1e-16 60.8 0.0 2.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ADH_N PF08240.12 KEZ34886.1 - 5.5e-31 106.7 1.1 1.2e-30 105.6 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ34886.1 - 1e-19 70.8 1.5 1e-19 70.8 1.5 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ34886.1 - 6.4e-10 40.2 1.0 1.8e-09 38.7 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KEZ34886.1 - 0.0012 19.0 1.1 0.0033 17.7 1.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 KEZ34886.1 - 0.0019 18.2 0.1 0.0034 17.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ34886.1 - 0.039 14.2 0.6 0.11 12.7 0.6 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KEZ34886.1 - 0.061 12.8 1.4 0.11 11.9 1.4 1.6 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus MTS PF05175.14 KEZ34886.1 - 0.084 12.4 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain ThiF PF00899.21 KEZ34886.1 - 0.11 11.8 0.3 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 ThiF family ADD_DNMT3 PF17980.1 KEZ34886.1 - 0.16 11.9 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Cpn60_TCP1 PF00118.24 KEZ34887.1 - 1.1e-83 281.5 3.6 1.9e-83 280.7 3.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family KfrA_N PF11740.8 KEZ34887.1 - 0.21 12.2 9.5 0.34 11.6 1.8 3.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Zip PF02535.22 KEZ34888.1 - 2.5e-06 27.0 9.1 2.5e-06 27.0 9.1 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter Cu-oxidase_3 PF07732.15 KEZ34889.1 - 6.9e-26 90.6 1.7 3.4e-23 81.9 0.2 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEZ34889.1 - 1.2e-25 89.8 4.3 1e-13 51.2 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase HTH_8 PF02954.19 KEZ34891.1 - 5.6e-13 48.4 0.9 5.6e-13 48.4 0.9 2.2 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family GAF PF01590.26 KEZ34891.1 - 9.9e-05 23.0 0.0 0.00025 21.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain HTH_50 PF18024.1 KEZ34891.1 - 0.00025 20.6 0.1 0.00059 19.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma54_activat PF00158.26 KEZ34891.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Hydantoinase_A PF01968.18 KEZ34892.1 - 1.4e-54 185.3 3.5 4.4e-54 183.7 0.9 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ34892.1 - 6.7e-16 58.5 5.8 1.4e-15 57.5 0.2 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KEZ34892.1 - 0.018 13.7 1.0 0.032 12.8 0.2 1.7 2 0 0 2 2 2 0 MutL protein StbA PF06406.11 KEZ34892.1 - 0.031 13.5 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 StbA protein Acetone_carb_G PF08882.11 KEZ34893.1 - 1.9e-38 131.1 0.7 2.6e-38 130.7 0.7 1.1 1 0 0 1 1 1 1 Acetone carboxylase gamma subunit TF_Zn_Ribbon PF08271.12 KEZ34893.1 - 0.0096 15.4 0.4 1.9 8.1 0.0 2.7 2 0 0 2 2 2 2 TFIIB zinc-binding NUDIX PF00293.28 KEZ34893.1 - 0.07 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Nudix_N_2 PF14803.6 KEZ34893.1 - 0.15 12.0 2.9 9.1 6.3 0.3 2.4 2 0 0 2 2 2 0 Nudix N-terminal Zn_ribbon_SprT PF17283.2 KEZ34893.1 - 0.63 10.0 4.6 14 5.7 0.0 3.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Hydantoinase_A PF01968.18 KEZ34894.1 - 2.4e-72 243.7 0.0 5.9e-70 235.8 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ34894.1 - 2.4e-39 134.9 0.5 6.9e-39 133.4 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KEZ34894.1 - 0.062 11.9 0.8 5.8 5.4 0.1 2.2 2 0 0 2 2 2 0 MutL protein Hydantoinase_B PF02538.14 KEZ34895.1 - 1.5e-85 287.6 0.7 1.7e-85 287.4 0.7 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase CoA_trans PF01144.23 KEZ34897.1 - 8.7e-66 221.4 0.0 1e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 KEZ34898.1 - 1.9e-43 148.4 0.5 2.1e-43 148.2 0.5 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KEZ34898.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Lon_C PF05362.13 KEZ34899.1 - 1.1e-76 256.9 0.2 1.3e-76 256.7 0.2 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 KEZ34899.1 - 3.1e-07 30.2 0.0 4.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Birna_VP4 PF01768.16 KEZ34899.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein RNase_T PF00929.24 KEZ34901.1 - 2.4e-25 90.0 0.0 2.9e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Response_reg PF00072.24 KEZ34902.1 - 7.3e-27 93.8 0.0 1.3e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ34902.1 - 6.3e-23 80.1 0.3 1e-22 79.4 0.3 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ34902.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KEZ34902.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KEZ34902.1 - 0.00025 20.5 0.2 0.00049 19.6 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 KEZ34902.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 KEZ34902.1 - 0.0016 18.2 1.4 0.087 12.6 0.0 3.1 3 0 0 3 3 3 1 HTH DNA binding domain HTH_24 PF13412.6 KEZ34902.1 - 0.0049 16.4 0.1 0.0083 15.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KEZ34902.1 - 0.0094 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 KEZ34902.1 - 0.029 14.2 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ34902.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Aldedh PF00171.22 KEZ34903.1 - 3e-88 296.4 0.0 4.2e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_3 PF07859.13 KEZ34903.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.21 KEZ34904.1 - 7.5e-27 93.7 0.0 1.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase HCV_NS5a_C PF12941.7 KEZ34905.1 - 0.00055 19.8 0.1 0.00085 19.2 0.1 1.2 1 0 0 1 1 1 1 HCV NS5a protein C-terminal region ABC_membrane PF00664.23 KEZ34907.1 - 2.2e-75 253.8 15.5 9.2e-40 137.0 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ34907.1 - 1.2e-67 226.6 0.0 2.7e-34 118.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ34907.1 - 5.5e-08 32.5 0.2 0.037 13.5 0.0 3.8 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KEZ34907.1 - 8.6e-08 31.7 0.0 0.0044 16.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 KEZ34907.1 - 2.6e-07 30.3 0.3 0.029 14.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_membrane_3 PF13748.6 KEZ34907.1 - 3.7e-07 29.6 25.2 1.5e-05 24.3 9.5 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_22 PF13401.6 KEZ34907.1 - 5e-06 26.8 0.4 0.056 13.7 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KEZ34907.1 - 2.3e-05 24.2 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEZ34907.1 - 3.5e-05 24.3 11.9 0.0062 16.9 0.5 3.9 3 2 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ34907.1 - 6.2e-05 23.0 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 KEZ34907.1 - 7.2e-05 23.2 0.0 0.8 10.1 0.0 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KEZ34907.1 - 7.8e-05 22.9 0.3 0.2 11.7 0.2 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain APS_kinase PF01583.20 KEZ34907.1 - 9.1e-05 22.4 0.1 0.021 14.8 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_15 PF13175.6 KEZ34907.1 - 0.0004 20.2 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KEZ34907.1 - 0.00041 20.4 0.6 1.5 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEZ34907.1 - 0.00077 19.1 1.8 0.49 9.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KEZ34907.1 - 0.0014 19.1 0.1 0.68 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ34907.1 - 0.0019 18.4 1.6 0.92 9.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 KEZ34907.1 - 0.0062 15.7 0.0 1 8.5 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KEZ34907.1 - 0.0084 16.2 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 KEZ34907.1 - 0.0089 16.0 0.0 0.16 12.0 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KEZ34907.1 - 0.012 15.4 0.1 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 KEZ34907.1 - 0.021 14.7 0.6 2.7 7.9 0.0 3.6 4 0 0 4 4 4 0 NTPase AAA_7 PF12775.7 KEZ34907.1 - 0.025 14.1 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KEZ34907.1 - 0.036 14.0 2.2 7.2 6.5 0.0 3.4 3 0 0 3 3 3 0 NACHT domain AAA_21 PF13304.6 KEZ34907.1 - 0.044 13.6 2.0 6.1 6.5 0.0 3.5 2 2 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KEZ34907.1 - 0.045 13.1 0.3 2 7.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cytidylate_kin PF02224.18 KEZ34907.1 - 0.059 13.1 0.9 4.7 6.9 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase Sigma54_activat PF00158.26 KEZ34907.1 - 0.071 12.8 0.0 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain G-alpha PF00503.20 KEZ34907.1 - 0.085 12.0 0.0 9.4 5.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 KEZ34907.1 - 0.086 13.3 0.0 3.4 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KEZ34907.1 - 0.13 9.8 0.1 1.2 6.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) RNA_helicase PF00910.22 KEZ34907.1 - 0.15 12.5 0.0 19 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.7 KEZ34907.1 - 0.16 10.9 0.1 0.56 9.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.22 KEZ34907.1 - 0.16 11.1 0.5 17 4.5 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain AAA_30 PF13604.6 KEZ34907.1 - 0.23 11.2 9.8 0.93 9.2 2.0 3.4 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KEZ34907.1 - 0.61 10.4 4.1 28 5.0 0.4 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4191 PF13829.6 KEZ34907.1 - 1 8.6 10.4 0.31 10.4 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Phage_integrase PF00589.22 KEZ34908.1 - 4.2e-20 72.2 0.0 2.4e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ34908.1 - 1.8e-10 40.9 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Sun2_CC2 PF18580.1 KEZ34908.1 - 0.0061 16.8 0.6 0.024 14.9 0.0 2.3 2 1 0 2 2 2 1 SUN2 coiled coil domain 2 AP2 PF00847.20 KEZ34908.1 - 0.012 15.8 0.4 0.038 14.2 0.4 1.8 1 0 0 1 1 1 0 AP2 domain Phage_int_SAM_1 PF02899.17 KEZ34908.1 - 0.039 14.2 0.1 0.039 14.2 0.1 2.9 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain GRAS PF03514.14 KEZ34908.1 - 0.14 11.0 0.1 8.5 5.2 0.0 2.1 2 0 0 2 2 2 0 GRAS domain family H_kinase_N PF12282.8 KEZ34910.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Signal transduction histidine kinase HTH_17 PF12728.7 KEZ34911.1 - 6.2e-18 64.7 0.0 7e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34911.1 - 0.00019 21.4 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ34911.1 - 0.002 18.4 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 KEZ34911.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Phage_AlpA PF05930.12 KEZ34911.1 - 0.0039 17.0 0.0 0.0052 16.6 0.0 1.3 1 1 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) AbiEi_4 PF13338.6 KEZ34911.1 - 0.017 15.3 0.2 0.049 13.8 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_28 PF13518.6 KEZ34911.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KEZ34911.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KEZ34911.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn helix UPF0175 PF03683.13 KEZ34911.1 - 0.17 11.6 0.0 0.51 10.1 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0175) FtsK_SpoIIIE PF01580.18 KEZ34914.1 - 1.2e-10 41.2 0.0 2.9e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ34914.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KEZ34914.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2142 PF09913.9 KEZ34915.1 - 0.12 11.2 0.3 0.14 11.0 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) HTH_31 PF13560.6 KEZ34917.1 - 1.6e-08 34.8 6.7 2.8e-08 34.0 6.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ34917.1 - 3.8e-07 30.1 0.1 7.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 KEZ34917.1 - 4.9e-06 26.9 0.2 8.3e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_35 PF13693.6 KEZ34917.1 - 0.0018 18.3 0.7 0.59 10.2 0.6 2.2 1 1 1 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_24 PF13412.6 KEZ34917.1 - 0.012 15.1 1.0 0.082 12.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KEZ34917.1 - 0.037 13.8 3.0 6.1 6.7 0.9 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_37 PF13744.6 KEZ34917.1 - 0.038 14.0 0.3 0.056 13.4 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PilJ PF13675.6 KEZ34917.1 - 0.42 10.6 5.5 0.54 10.3 5.5 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term HTH_38 PF13936.6 KEZ34917.1 - 3.2 7.6 6.3 8.4 6.2 0.6 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain AsnC_trans_reg PF01037.21 KEZ34918.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain HTH_3 PF01381.22 KEZ34920.1 - 1.7e-05 24.8 0.0 5e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ34920.1 - 9e-05 22.8 0.0 0.0018 18.5 0.0 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain TPR_12 PF13424.6 KEZ34920.1 - 9.7e-05 22.6 10.5 0.0099 16.2 2.7 3.7 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_37 PF13744.6 KEZ34920.1 - 0.0098 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ34920.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ34920.1 - 0.05 13.1 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 TPR_2 PF07719.17 KEZ34920.1 - 0.45 10.7 7.6 24 5.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat 2_5_RNA_ligase2 PF13563.6 KEZ34921.1 - 1.4e-13 51.0 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KEZ34921.1 - 5.5e-05 23.3 0.0 0.052 13.8 0.0 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase Formyl_trans_N PF00551.19 KEZ34922.1 - 1.4e-39 135.8 0.0 1.5e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase EH_Signature PF15611.6 KEZ34923.1 - 0.13 11.6 1.9 0.38 10.1 0.1 2.0 1 1 0 2 2 2 0 EH_Signature domain CSD PF00313.22 KEZ34925.1 - 0.0095 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain FGE-sulfatase PF03781.16 KEZ34926.1 - 9.6e-31 107.3 1.0 1.5e-30 106.7 1.0 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 NACHT PF05729.12 KEZ34926.1 - 9.4e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KEZ34926.1 - 6.3e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ34926.1 - 0.0012 19.3 0.2 0.0075 16.7 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEZ34926.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.29 KEZ34926.1 - 0.003 18.0 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEZ34926.1 - 0.0034 17.7 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEZ34926.1 - 0.0056 15.8 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KEZ34926.1 - 0.0082 16.4 0.1 0.036 14.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ34926.1 - 0.021 15.3 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEZ34926.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KEZ34926.1 - 0.024 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KEZ34926.1 - 0.033 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KEZ34926.1 - 0.044 13.5 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ34926.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ34926.1 - 0.056 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KEZ34926.1 - 0.067 12.8 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.21 KEZ34926.1 - 0.076 12.5 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 KEZ34926.1 - 0.08 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KEZ34926.1 - 0.092 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEZ34926.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KEZ34926.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 KEZ34926.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.6 KEZ34926.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_25 PF13649.6 KEZ34927.1 - 2.3e-09 37.8 0.0 6.7e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ34927.1 - 1.6e-08 35.1 0.0 3.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ34927.1 - 3.6e-08 34.1 0.0 6.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ34927.1 - 7.6e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ34927.1 - 0.00017 21.4 0.0 0.0004 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ34927.1 - 0.0064 16.3 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KEZ34927.1 - 0.0074 15.7 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ34927.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 KEZ34927.1 - 0.2 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF72 PF01904.18 KEZ34928.1 - 1.1e-14 55.1 0.2 1.3e-14 54.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 Putative_PNPOx PF01243.20 KEZ34928.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PhoD PF09423.10 KEZ34929.1 - 3.4e-73 246.7 0.0 4.8e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KEZ34929.1 - 6.6e-19 68.2 0.8 1.6e-18 67.0 0.8 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain HTH_Tnp_1 PF01527.20 KEZ34930.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 KEZ34934.1 - 3.9e-21 75.3 0.0 4.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF86 PF01934.17 KEZ34935.1 - 1.1e-20 73.6 0.4 1e-19 70.5 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF86 Polbeta PF18765.1 KEZ34936.1 - 7e-09 35.7 0.0 7.7e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KEZ34936.1 - 9e-09 35.5 0.0 1.1e-08 35.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain TadZ_N PF16968.5 KEZ34936.1 - 0.068 12.9 0.8 7 6.4 0.0 2.0 1 1 1 2 2 2 0 Pilus assembly protein TadZ N-terminal Abhydrolase_1 PF00561.20 KEZ34937.1 - 1e-30 107.2 0.0 4.5e-30 105.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ34937.1 - 1.8e-10 40.5 0.0 8.5e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ34937.1 - 2.1e-08 35.0 8.3 2.8e-08 34.6 8.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KEZ34937.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 KEZ34937.1 - 0.0081 14.9 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 KEZ34937.1 - 0.027 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Transposase_31 PF04754.12 KEZ34939.1 - 0.00024 20.8 0.0 0.00028 20.6 0.0 1.0 1 0 0 1 1 1 1 Putative transposase, YhgA-like Sulfatase PF00884.23 KEZ34940.1 - 6.6e-53 180.1 1.0 8.1e-53 179.8 1.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEZ34940.1 - 6.6e-08 32.5 0.3 3.1e-07 30.3 0.3 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KEZ34940.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) MarR_2 PF12802.7 KEZ34942.1 - 4.7e-10 39.2 0.6 3e-09 36.6 0.0 2.4 2 1 0 2 2 2 1 MarR family HTH_27 PF13463.6 KEZ34942.1 - 1.6e-06 28.5 0.0 4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 KEZ34942.1 - 0.00028 20.8 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KEZ34942.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KEZ34942.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 KEZ34942.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 LZ_Tnp_IS481 PF13011.6 KEZ34942.1 - 0.079 13.5 0.2 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 TrmB PF01978.19 KEZ34942.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r2 PF04542.14 KEZ34943.1 - 0.00017 21.3 0.1 0.00033 20.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 NTP_transf_2 PF01909.23 KEZ34944.1 - 7.8e-05 22.9 0.1 9.2e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEZ34944.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nterm_IS4 PF13006.7 KEZ34946.1 - 8.1e-35 118.9 0.1 1.7e-34 117.9 0.1 1.6 1 0 0 1 1 1 1 Insertion element 4 transposase N-terminal DDE_Tnp_1 PF01609.21 KEZ34946.1 - 1.3e-08 34.8 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain AAA_31 PF13614.6 KEZ34948.1 - 1e-29 103.7 0.0 1.9e-29 102.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ34948.1 - 3.8e-16 59.3 0.0 3.5e-15 56.2 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KEZ34948.1 - 1.5e-08 34.4 0.0 1.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KEZ34948.1 - 2.3e-08 33.8 0.0 1.2e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KEZ34948.1 - 3.8e-07 29.6 0.0 8.6e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 KEZ34948.1 - 1.2e-05 24.7 0.0 0.0022 17.3 0.0 2.4 2 0 0 2 2 2 2 VirC1 protein MipZ PF09140.11 KEZ34948.1 - 1.9e-05 24.1 0.1 0.0002 20.7 0.1 2.0 2 0 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.18 KEZ34948.1 - 0.00046 19.7 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 KEZ34948.1 - 0.0052 15.8 0.1 0.019 13.9 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KEZ34948.1 - 0.014 15.0 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KEZ34948.1 - 0.022 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 KEZ34948.1 - 0.082 12.5 0.0 0.83 9.2 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF262 PF03235.14 KEZ34949.1 - 1.4e-34 120.2 0.4 3.3e-34 119.0 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 HEPN_MAE_28990 PF18737.1 KEZ34950.1 - 0.00079 19.4 0.0 0.00084 19.3 0.0 1.1 1 0 0 1 1 1 1 MAE_28990/MAE_18760-like HEPN HEPN_RiboL-PSP PF18735.1 KEZ34950.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.3 1 1 0 1 1 1 1 RiboL-PSP-HEPN MaAIMP_sms PF16951.5 KEZ34951.1 - 0.00045 19.9 1.4 0.00045 19.9 1.4 2.2 2 1 1 3 3 3 1 Putative methionine and alanine importer, small subunit Myc_target_1 PF15179.6 KEZ34951.1 - 0.15 11.9 0.2 0.17 11.8 0.2 1.1 1 0 0 1 1 1 0 Myc target protein 1 TetR_N PF00440.23 KEZ34952.1 - 1.9e-08 34.0 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 KEZ34952.1 - 0.00027 20.8 0.0 0.0031 17.3 0.0 2.0 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Cpn60_TCP1 PF00118.24 KEZ34954.1 - 1.4e-97 327.4 7.6 1.8e-97 327.0 7.6 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP20 PF00011.21 KEZ34955.1 - 7.1e-23 80.7 0.0 8.6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEZ34955.1 - 4.2e-10 39.0 0.2 6.5e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP70 PF00012.20 KEZ34956.1 - 2.7e-238 792.1 0.7 3.2e-238 791.8 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ34956.1 - 8.3e-17 61.0 0.7 1.8e-14 53.3 0.2 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KEZ34956.1 - 0.0014 18.4 0.5 0.0031 17.3 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KEZ34956.1 - 0.013 14.7 0.3 0.035 13.3 0.0 1.8 3 0 0 3 3 3 0 StbA protein GrpE PF01025.19 KEZ34957.1 - 4.8e-30 104.4 0.0 5.3e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 GrpE Metal_resist PF13801.6 KEZ34957.1 - 5.6 7.2 16.4 0.15 12.3 8.5 2.3 2 1 0 2 2 2 0 Heavy-metal resistance DnaJ_C PF01556.18 KEZ34958.1 - 8.7e-30 103.8 0.0 1.1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ34958.1 - 2.4e-20 72.4 0.0 3.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ34959.1 - 0.0029 17.9 1.2 0.004 17.5 1.2 1.3 1 0 0 1 1 1 1 DnaJ central domain MeaB PF03308.16 KEZ34960.1 - 3.5e-93 311.5 6.6 4.7e-93 311.0 6.6 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KEZ34960.1 - 3.2e-05 23.6 1.0 0.00024 20.8 1.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KEZ34960.1 - 0.00013 21.7 0.5 0.00013 21.7 0.5 2.5 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KEZ34960.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ34960.1 - 0.0026 17.8 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KEZ34960.1 - 0.012 16.1 0.1 0.031 14.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KEZ34960.1 - 0.012 15.4 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KEZ34960.1 - 0.017 15.2 0.5 0.09 12.9 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 KEZ34960.1 - 0.019 14.6 0.3 0.11 12.2 0.3 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ParA PF10609.9 KEZ34960.1 - 0.021 14.3 0.3 0.039 13.4 0.3 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 KEZ34960.1 - 0.031 13.6 0.1 0.42 9.9 0.1 2.3 1 1 0 1 1 1 0 VirC1 protein AAA_25 PF13481.6 KEZ34960.1 - 0.06 12.9 3.0 0.065 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEZ34960.1 - 0.061 13.8 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KEZ34960.1 - 0.063 13.2 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 NTPase TrwB_AAD_bind PF10412.9 KEZ34960.1 - 0.088 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 KEZ34960.1 - 0.27 11.5 1.8 0.32 11.2 0.4 1.8 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KEZ34960.1 - 0.38 9.9 0.6 0.66 9.1 0.6 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_16 PF13191.6 KEZ34960.1 - 0.4 11.1 6.3 3 8.2 6.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain MM_CoA_mutase PF01642.22 KEZ34961.1 - 4.9e-133 444.4 0.0 8.6e-72 242.3 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl-CoA mutase B12-binding PF02310.19 KEZ34961.1 - 8.3e-17 61.3 1.7 1.9e-16 60.2 1.7 1.7 1 0 0 1 1 1 1 B12 binding domain MaoC_dehydratas PF01575.19 KEZ34962.1 - 1.6e-18 66.4 0.1 2e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KEZ34962.1 - 0.00018 21.7 0.1 0.00027 21.1 0.1 1.3 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Acyl-CoA_dh_1 PF00441.24 KEZ34963.1 - 1.5e-47 161.5 4.6 1.5e-47 161.5 4.6 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ34963.1 - 1.1e-34 119.5 0.1 3e-34 118.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ34963.1 - 8e-20 70.9 0.1 2e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ34963.1 - 3.3e-18 66.2 1.1 5.6e-18 65.5 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpcH_HpaI PF03328.14 KEZ34964.1 - 9.9e-47 158.9 0.0 1.3e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEZ34964.1 - 1.1e-07 31.4 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Malate_synthase PF01274.22 KEZ34964.1 - 0.0013 17.1 0.4 0.61 8.3 0.0 3.4 3 1 1 4 4 4 2 Malate synthase AMP-binding PF00501.28 KEZ34965.1 - 1.7e-85 287.2 0.0 2e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ34965.1 - 8.9e-23 81.1 0.5 8.9e-23 81.1 0.5 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain LacI PF00356.21 KEZ34966.1 - 5.7e-15 54.8 1.4 1.2e-14 53.8 1.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_3 PF13377.6 KEZ34966.1 - 4e-12 46.8 0.0 8.3e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KEZ34966.1 - 3.3e-10 39.8 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_3 PF01381.22 KEZ34966.1 - 0.012 15.6 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 KEZ34966.1 - 0.014 15.7 3.4 0.043 14.2 3.2 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ34966.1 - 0.031 13.7 0.0 0.083 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KEZ34966.1 - 0.054 13.3 0.1 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 KEZ34966.1 - 0.088 13.0 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ34966.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.19 KEZ34966.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein HTH_IclR PF09339.10 KEZ34966.1 - 0.16 11.8 1.7 0.43 10.4 0.1 2.5 1 1 1 2 2 2 0 IclR helix-turn-helix domain SpoIIE PF07228.12 KEZ34967.1 - 3.6e-25 89.0 0.8 3.9e-25 88.9 0.8 1.0 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) ketoacyl-synt PF00109.26 KEZ34968.1 - 1e-47 162.9 3.9 1e-47 162.9 3.9 2.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ34968.1 - 4.3e-32 110.6 3.0 1e-31 109.4 3.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KEZ34968.1 - 4.4e-07 29.5 0.8 1.1e-06 28.2 0.5 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Phytase-like PF13449.6 KEZ34968.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Esterase-like activity of phytase KAsynt_C_assoc PF16197.5 KEZ34968.1 - 0.13 12.7 0.0 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Pilin_PilA PF14245.6 KEZ34968.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Type IV pilin PilA DUF3463 PF11946.8 KEZ34969.1 - 4.1e-55 185.2 0.0 1.5e-54 183.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3463) Radical_SAM PF04055.21 KEZ34969.1 - 3.1e-20 73.2 0.0 5.1e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KEZ34969.1 - 0.00018 21.7 0.0 0.0006 19.9 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KEZ34969.1 - 0.0013 19.0 0.2 0.0037 17.5 0.1 1.8 1 1 1 2 2 2 1 4Fe-4S single cluster domain TetR_N PF00440.23 KEZ34970.1 - 9.2e-09 35.0 0.0 1.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 KEZ34970.1 - 0.00014 21.7 0.5 0.0034 17.2 0.0 2.6 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain FAD_binding_3 PF01494.19 KEZ34972.1 - 4.9e-12 45.8 0.5 2.5e-10 40.2 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KEZ34972.1 - 2.1e-06 26.9 0.2 0.0015 17.5 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 KEZ34972.1 - 4e-06 26.7 0.7 0.083 12.5 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ34972.1 - 5.8e-05 22.0 0.0 0.0078 15.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ34972.1 - 0.00068 18.9 0.0 0.0037 16.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ34972.1 - 0.001 18.2 0.1 0.0018 17.4 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEZ34972.1 - 0.0015 17.7 1.2 0.18 10.8 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KEZ34972.1 - 0.0041 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ34972.1 - 0.015 15.3 1.3 0.48 10.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEZ34972.1 - 0.018 15.2 0.1 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ34972.1 - 0.078 13.6 0.0 2.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEZ34972.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Dyp_perox PF04261.12 KEZ34974.1 - 2.3e-76 256.9 0.0 2.9e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Metallophos PF00149.28 KEZ34975.1 - 3.4e-08 34.2 0.5 5.4e-08 33.6 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KEZ34975.1 - 8.9e-05 23.0 0.0 0.00023 21.7 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KEZ34975.1 - 0.00014 22.3 0.0 0.0003 21.3 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Metallophos_2 PF12850.7 KEZ34975.1 - 0.06 13.5 0.0 0.23 11.6 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Fer4_15 PF13459.6 KEZ34977.1 - 2.4e-13 50.6 0.0 2.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KEZ34977.1 - 2.4e-05 24.8 0.0 4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Complex1_51K PF01512.17 KEZ34978.1 - 4.8e-29 101.2 0.0 9.3e-23 80.8 0.0 2.2 2 0 0 2 2 2 2 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KEZ34978.1 - 1.3e-17 63.6 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KEZ34978.1 - 3e-08 33.4 2.1 7.2e-08 32.2 2.1 1.7 1 0 0 1 1 1 1 SLBB domain Ferric_reduct PF01794.19 KEZ34979.1 - 1e-10 41.8 5.7 1e-10 41.8 5.7 1.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.6 KEZ34979.1 - 8.3 7.0 11.3 2.1 9.0 2.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) ApbE PF02424.15 KEZ34980.1 - 3.9e-47 160.9 0.0 5.3e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 ApbE family ABA_WDS PF02496.16 KEZ34981.1 - 0.099 13.1 0.5 0.15 12.6 0.5 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein DUF515 PF04415.12 KEZ34981.1 - 6.2 5.1 8.7 5.9 5.2 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Na_H_antiport_1 PF06965.12 KEZ34983.1 - 2.3e-133 444.7 21.8 2.6e-133 444.5 21.8 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 Cas3_C PF18395.1 KEZ34984.1 - 3.7e-05 24.2 0.0 6.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Cas3 C-terminal domain Bac_globin PF01152.21 KEZ34985.1 - 6e-24 84.5 0.0 6.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 KEZ34985.1 - 0.00063 19.7 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Protoglobin NHL PF01436.21 KEZ34986.1 - 0.22 11.7 1.9 3.9 7.7 0.4 2.6 2 1 0 2 2 2 0 NHL repeat CHAT PF12770.7 KEZ34992.1 - 1.8e-32 113.0 0.3 4.6e-32 111.6 0.3 1.7 1 0 0 1 1 1 1 CHAT domain Urocanase PF01175.18 KEZ34994.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain AbiEi_4 PF13338.6 KEZ34994.1 - 4 7.7 8.1 7.2 6.9 0.3 3.8 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin DUF4065 PF13274.6 KEZ34995.1 - 2.5e-05 25.1 0.1 3.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4065) DDE_Tnp_IS66 PF03050.14 KEZ34996.1 - 5e-06 26.2 0.1 5.6e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66 PF03050.14 KEZ34997.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family zf-IS66 PF13005.7 KEZ34997.1 - 0.0001 22.6 1.5 0.00019 21.8 1.5 1.5 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 Recombinase PF07508.13 KEZ34998.1 - 2.9e-10 40.5 0.0 5.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 KEZ34998.1 - 0.037 14.5 0.7 0.063 13.8 0.7 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain NUDIX PF00293.28 KEZ34999.1 - 8e-19 68.0 0.2 1.1e-18 67.5 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain BATS PF06968.13 KEZ35000.1 - 8.3e-16 57.9 0.0 4.6e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KEZ35000.1 - 1.8e-13 51.2 0.0 6e-13 49.5 0.0 1.9 3 0 0 3 3 3 1 Radical SAM superfamily TPR_12 PF13424.6 KEZ35001.1 - 2.7e-73 242.2 47.1 4e-18 65.5 0.4 6.1 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ35001.1 - 1e-60 200.1 45.3 4.2e-10 39.1 0.1 8.9 9 0 0 9 9 8 8 Tetratricopeptide repeat TIR_2 PF13676.6 KEZ35001.1 - 6.6e-27 94.5 0.0 1.4e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 TIR domain TPR_7 PF13176.6 KEZ35001.1 - 5.4e-26 88.7 26.2 0.00048 20.0 0.1 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ35001.1 - 6.6e-23 79.5 15.8 0.00093 18.9 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ35001.1 - 2.9e-19 67.6 21.3 0.0049 16.9 0.1 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ35001.1 - 3.1e-13 50.0 29.3 8e-05 23.1 0.1 6.5 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ35001.1 - 4.2e-12 45.3 12.5 0.076 13.3 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat PPR PF01535.20 KEZ35001.1 - 4e-11 42.4 0.0 1.1 9.7 0.0 6.4 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.6 KEZ35001.1 - 7.8e-08 32.5 50.8 0.018 15.8 0.4 10.9 9 2 2 11 11 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ35001.1 - 4e-07 30.6 24.8 8.1e-05 23.2 3.6 9.5 8 3 1 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ35001.1 - 5e-07 29.9 32.5 0.53 11.0 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_3 PF07720.12 KEZ35001.1 - 1.3e-05 25.1 10.7 3.6 7.7 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ35001.1 - 1.8e-05 24.9 2.6 0.0022 18.4 0.2 12.1 11 1 0 11 11 9 4 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ35001.1 - 1.8e-05 25.2 0.8 1.8e-05 25.2 0.8 2.7 2 2 0 2 2 2 1 AAA ATPase domain PPR_1 PF12854.7 KEZ35001.1 - 0.0036 17.0 0.5 23 4.8 0.1 4.5 4 0 0 4 4 4 0 PPR repeat TPR_17 PF13431.6 KEZ35001.1 - 0.0082 16.5 20.4 19 5.9 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ35001.1 - 0.026 14.2 12.3 1.5 8.6 0.0 6.2 7 0 0 7 7 7 0 TPR repeat NB-ARC PF00931.22 KEZ35001.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 KEZ35002.1 - 3e-47 161.2 0.0 4e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ35002.1 - 1.2e-27 96.8 0.0 1.7e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NHL PF01436.21 KEZ35002.1 - 2.9e-20 71.2 11.5 7.9e-05 22.5 0.2 6.8 6 0 0 6 6 6 5 NHL repeat SGL PF08450.12 KEZ35002.1 - 2.7e-07 30.4 0.0 6.5e-05 22.6 0.0 3.4 2 2 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 KEZ35002.1 - 0.00099 19.1 0.1 0.28 11.1 0.0 3.3 3 2 1 5 5 5 1 Esterase-like activity of phytase Pkinase_fungal PF17667.1 KEZ35002.1 - 0.027 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KEZ35002.1 - 0.078 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 KEZ35003.1 - 5.9e-69 226.3 24.2 1.3e-09 38.5 0.0 13.2 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ35003.1 - 4.4e-21 75.0 0.0 0.76 10.1 0.0 11.5 7 3 4 12 12 12 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ35003.1 - 3.3e-13 49.3 0.8 0.34 9.8 0.0 7.4 4 3 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ35003.1 - 1.2e-09 37.8 3.5 6.3 6.9 0.1 8.4 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KEZ35003.1 - 2.9e-06 27.8 0.3 2.9e-06 27.8 0.3 2.9 2 0 0 2 2 2 1 AAA ATPase domain eIF2A PF08662.11 KEZ35003.1 - 0.00025 21.0 0.0 3.2 7.6 0.0 4.6 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KEZ35003.1 - 0.00068 18.3 0.1 0.22 10.0 0.0 3.4 2 1 2 4 4 4 1 Cytochrome D1 heme domain AAA_29 PF13555.6 KEZ35003.1 - 0.011 15.4 0.4 0.11 12.2 0.1 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ35003.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Nbas_N PF15492.6 KEZ35003.1 - 0.62 9.3 6.0 54 3.0 0.0 5.5 6 1 1 7 7 7 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 KEZ35003.1 - 2.1 8.1 18.0 10 5.9 0.2 7.5 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature Sigma70_r2 PF04542.14 KEZ35004.1 - 8e-13 48.0 1.3 1.5e-12 47.1 1.3 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ35004.1 - 7.3e-09 35.2 0.2 7.3e-09 35.2 0.2 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KEZ35004.1 - 3.3e-05 23.9 0.3 6.1e-05 23.0 0.3 1.4 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 KEZ35004.1 - 0.0065 16.0 0.2 0.0065 16.0 0.2 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 DUF3151 PF11349.8 KEZ35004.1 - 0.071 13.2 0.1 0.071 13.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3151) MgtE_N PF03448.17 KEZ35004.1 - 0.084 13.5 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain DUF677 PF05055.12 KEZ35005.1 - 0.51 9.2 4.5 0.74 8.6 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PAS PF00989.25 KEZ35008.1 - 1.6e-12 47.4 0.0 1.9e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KEZ35008.1 - 9.9e-11 41.4 0.1 1.1e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KEZ35008.1 - 1.6e-08 34.7 0.0 1.7e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KEZ35008.1 - 4.2e-06 27.0 0.0 4.7e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KEZ35008.1 - 0.068 13.5 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS_7 PF12860.7 KEZ35008.1 - 0.093 12.9 0.0 0.1 12.7 0.0 1.0 1 0 0 1 1 1 0 PAS fold HATPase_c PF02518.26 KEZ35009.1 - 7.2e-20 71.6 0.0 1.4e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ35009.1 - 2.8e-16 59.7 0.0 4.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEZ35009.1 - 1.1e-06 28.6 1.6 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HPTransfase PF10090.9 KEZ35009.1 - 0.00033 20.5 0.1 0.026 14.3 0.0 2.5 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 KEZ35009.1 - 0.0052 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2894 PF11445.8 KEZ35010.1 - 6.3 7.2 8.9 3 8.3 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) FAD_binding_3 PF01494.19 KEZ35011.1 - 3.8e-11 42.8 0.1 4.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ35011.1 - 9e-09 35.4 2.0 1e-05 25.3 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ35011.1 - 2.2e-06 27.8 0.1 4.7e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ35011.1 - 2.6e-06 26.6 0.4 0.0031 16.4 0.1 3.0 3 0 0 3 3 3 2 Tryptophan halogenase SE PF08491.10 KEZ35011.1 - 1.6e-05 24.1 0.0 3.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase AlaDh_PNT_C PF01262.21 KEZ35011.1 - 0.00035 19.9 0.1 0.00057 19.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KEZ35011.1 - 0.00058 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ35011.1 - 0.011 16.3 0.2 0.023 15.3 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ35011.1 - 0.02 14.0 1.2 0.051 12.7 1.2 1.6 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KEZ35011.1 - 0.027 13.5 0.1 7.2 5.5 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KEZ35011.1 - 0.034 13.4 0.1 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEZ35011.1 - 0.036 12.8 0.1 0.052 12.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KEZ35011.1 - 0.056 12.8 0.1 0.12 11.7 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEZ35011.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF347 PF03988.12 KEZ35012.1 - 8.2e-33 112.4 45.5 2.7e-11 43.5 0.4 4.8 4 1 0 4 4 4 4 Repeat of Unknown Function (DUF347) DUF1775 PF07987.11 KEZ35014.1 - 7e-48 162.7 1.7 8.3e-48 162.4 1.7 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) NupH_GANP PF16768.5 KEZ35014.1 - 0.17 11.5 2.5 0.061 13.0 0.3 1.4 2 0 0 2 2 2 0 Nucleoporin homology of Germinal-centre associated nuclear protein CopD PF05425.13 KEZ35015.1 - 4.6e-24 84.8 6.5 4.6e-24 84.8 6.5 4.5 4 1 1 5 5 5 1 Copper resistance protein D CopC PF04234.12 KEZ35015.1 - 3.4e-20 72.9 0.1 1.5e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 CopC domain FixH PF05751.11 KEZ35015.1 - 0.015 15.3 0.0 0.056 13.5 0.0 1.9 1 0 0 1 1 1 0 FixH UPF0093 PF03653.13 KEZ35015.1 - 0.055 13.7 0.4 0.16 12.2 0.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) DUF4232 PF14016.6 KEZ35015.1 - 3 8.0 7.4 3.2 7.9 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Rubrerythrin PF02915.17 KEZ35016.1 - 2.2e-05 24.9 0.5 0.00073 19.9 0.0 2.3 1 1 1 2 2 2 1 Rubrerythrin CdiI_2 PF18593.1 KEZ35016.1 - 0.059 14.0 0.2 0.48 11.1 0.0 2.5 3 1 0 3 3 3 0 CdiI immunity protein PT PF04886.12 KEZ35017.1 - 0.016 14.8 3.2 0.016 14.8 3.2 1.8 2 0 0 2 2 2 0 PT repeat 4HBT PF03061.22 KEZ35017.1 - 0.037 14.4 0.4 0.037 14.4 0.4 1.7 2 0 0 2 2 2 0 Thioesterase superfamily PP-binding PF00550.25 KEZ35018.1 - 7.6e-14 51.8 0.9 9e-14 51.6 0.9 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1953 PF09196.10 KEZ35018.1 - 0.0068 16.2 0.4 0.01 15.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1953) FA_desaturase_2 PF03405.14 KEZ35019.1 - 2.1e-17 63.0 0.3 2.7e-17 62.6 0.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 KEZ35019.1 - 4.9e-06 27.0 0.2 0.00015 22.2 0.0 2.2 2 0 0 2 2 2 1 Rubrerythrin Ferritin PF00210.24 KEZ35019.1 - 1.1e-05 25.4 0.4 2e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain COQ7 PF03232.13 KEZ35019.1 - 0.072 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.6 KEZ35019.1 - 0.077 13.2 0.5 0.2 11.9 0.5 1.5 1 1 1 2 2 2 0 Ferritin-like domain DDE_Tnp_IS240 PF13610.6 KEZ35020.1 - 1.5e-09 38.2 1.0 2.5e-09 37.5 1.0 1.3 1 0 0 1 1 1 1 DDE domain rve PF00665.26 KEZ35020.1 - 0.00054 20.1 0.2 0.0009 19.4 0.2 1.4 1 0 0 1 1 1 1 Integrase core domain DNA_pol3_alpha PF07733.12 KEZ35021.1 - 3e-91 305.6 0.0 4.3e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 KEZ35021.1 - 3.8e-57 192.2 0.0 6.6e-57 191.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 KEZ35021.1 - 9.4e-50 169.2 0.0 1.7e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 KEZ35021.1 - 1.9e-27 95.3 0.1 1.1e-26 93.0 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 KEZ35021.1 - 6.6e-06 26.0 0.1 1.5e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DDE_Tnp_IS240 PF13610.6 KEZ35022.1 - 4.7e-42 143.5 0.0 6.2e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 DDE domain rve PF00665.26 KEZ35022.1 - 1.6e-06 28.3 0.3 3.2e-06 27.3 0.3 1.6 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_ISL3 PF01610.17 KEZ35022.1 - 5.6e-05 23.0 0.1 0.00021 21.1 0.0 1.8 1 1 1 2 2 2 1 Transposase DDE_Tnp_IS66 PF03050.14 KEZ35022.1 - 0.0091 15.5 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 Transposase IS66 family Sel1 PF08238.12 KEZ35022.1 - 0.092 13.5 0.1 30 5.5 0.0 2.7 2 0 0 2 2 2 0 Sel1 repeat DUF433 PF04255.14 KEZ35023.1 - 1.3e-23 82.6 0.1 1.7e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF433) DUF5615 PF18480.1 KEZ35024.1 - 1.4e-22 79.2 0.0 2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) PIN_10 PF18478.1 KEZ35024.1 - 2.8e-08 33.9 0.0 4.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 PIN like domain GUCT PF08152.12 KEZ35024.1 - 0.023 15.0 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 GUCT (NUC152) domain Mut7-C PF01927.16 KEZ35024.1 - 0.032 14.3 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain Resolvase PF00239.21 KEZ35025.1 - 2.6e-11 43.8 1.7 1.4e-10 41.5 1.7 1.8 1 1 0 1 1 1 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 KEZ35026.1 - 7.9e-09 35.9 0.1 1.8e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 KEZ35026.1 - 2.5e-08 34.2 0.1 5.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Recombinase ABATE PF07336.11 KEZ35026.1 - 0.17 12.6 4.5 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Sporozoite_P67 PF05642.11 KEZ35027.1 - 1.6 6.8 8.0 1.8 6.6 8.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDE_Tnp_IS240 PF13610.6 KEZ35029.1 - 4.1e-46 156.7 0.0 5.4e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 DDE domain rve PF00665.26 KEZ35029.1 - 1.3e-08 35.1 1.6 6.1e-08 32.9 1.6 2.0 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_IS66 PF03050.14 KEZ35029.1 - 7.2e-07 29.0 1.4 8.6e-07 28.7 1.4 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_ISL3 PF01610.17 KEZ35029.1 - 0.002 17.9 0.1 0.0042 16.8 0.0 1.5 1 1 1 2 2 2 1 Transposase HEM4 PF02602.15 KEZ35029.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD HTH_29 PF13551.6 KEZ35029.1 - 0.053 13.5 0.1 0.19 11.7 0.1 2.0 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 KEZ35029.1 - 0.32 11.6 3.0 0.55 10.9 0.3 2.5 1 1 1 2 2 2 0 Homeodomain-like domain 2-oxoacid_dh PF00198.23 KEZ35031.1 - 1.2e-65 221.2 0.0 3.1e-65 219.9 0.0 1.6 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 KEZ35031.1 - 5.3e-13 49.1 1.2 5.3e-13 49.1 1.2 2.0 2 0 0 2 2 2 1 e3 binding domain DUF1304 PF06993.12 KEZ35033.1 - 0.015 15.3 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) DUF202 PF02656.15 KEZ35033.1 - 0.16 12.4 0.7 0.21 12.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Acyl-CoA_dh_C PF12806.7 KEZ35034.1 - 5.8e-29 100.8 1.2 1.6e-28 99.3 0.9 1.9 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 KEZ35034.1 - 9.4e-21 73.8 0.0 1.9e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KEZ35034.1 - 8.5e-17 61.7 3.4 4.7e-16 59.3 0.8 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 KEZ35034.1 - 2.6e-10 40.1 0.0 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal CW_7 PF08230.11 KEZ35034.1 - 0.0067 16.1 0.2 0.039 13.7 0.0 2.4 2 0 0 2 2 2 1 CW_7 repeat Acyl-CoA_dh_N PF02771.16 KEZ35034.1 - 0.014 16.1 0.6 0.069 13.8 0.0 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEZ35034.1 - 0.02 15.2 1.9 0.042 14.1 0.0 2.5 4 0 0 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain DUF3376 PF11856.8 KEZ35035.1 - 2.5e-145 485.3 21.9 2.5e-145 485.3 21.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3376) Patatin PF01734.22 KEZ35035.1 - 2.2e-15 57.4 3.2 2.2e-15 57.4 3.2 2.8 2 2 1 3 3 3 1 Patatin-like phospholipase Nitroreductase PF00881.24 KEZ35037.1 - 1.4e-20 74.0 0.5 1.7e-20 73.8 0.5 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF4712 PF15830.5 KEZ35037.1 - 0.27 10.9 0.7 0.35 10.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) ABC_tran PF00005.27 KEZ35038.1 - 3.7e-08 34.0 0.1 4.1e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ35038.1 - 0.047 13.5 0.1 0.058 13.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ35038.1 - 0.2 12.1 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Guanylate_cyc PF00211.20 KEZ35039.1 - 2.2e-23 82.8 0.0 4.2e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KEZ35039.1 - 9.7e-22 78.1 0.1 9.7e-22 78.1 0.1 3.2 4 0 0 4 4 4 1 AAA ATPase domain TPR_12 PF13424.6 KEZ35039.1 - 2.3e-13 50.2 27.4 9.6e-05 22.6 0.4 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat DZR PF12773.7 KEZ35039.1 - 5.8e-05 23.0 0.6 0.00012 22.0 0.6 1.5 1 0 0 1 1 1 1 Double zinc ribbon TPR_19 PF14559.6 KEZ35039.1 - 0.00014 22.3 0.3 0.00014 22.3 0.3 6.0 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ35039.1 - 0.00024 21.0 22.0 0.19 11.9 2.3 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat SNAP PF14938.6 KEZ35039.1 - 0.0043 16.5 2.8 1.7 8.0 0.0 3.5 3 1 1 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KEZ35039.1 - 0.0088 16.7 1.3 0.0088 16.7 1.3 7.2 5 2 2 7 7 7 3 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 KEZ35039.1 - 0.011 15.1 2.5 0.019 14.3 2.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KEZ35039.1 - 0.023 14.4 4.9 0.04 13.6 4.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TPR_10 PF13374.6 KEZ35039.1 - 0.029 14.2 0.3 0.029 14.2 0.3 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ35039.1 - 0.15 12.8 10.1 18 6.2 0.2 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_5 PF07728.14 KEZ35039.1 - 0.16 12.0 0.0 0.93 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPR_1 PF00515.28 KEZ35039.1 - 0.27 11.1 3.4 25 4.9 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1771 PF08590.10 KEZ35039.1 - 0.78 10.2 6.2 1.6 9.2 0.0 4.0 3 0 0 3 3 2 0 Domain of unknown function (DUF1771) MtrG PF04210.13 KEZ35040.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G STAS_2 PF13466.6 KEZ35042.1 - 2.3e-15 56.7 3.9 2.8e-15 56.4 3.9 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KEZ35042.1 - 3.7e-05 23.3 0.0 4.2e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 STAS domain PGI PF00342.19 KEZ35043.1 - 7.5e-211 700.9 0.0 8.6e-211 700.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 KEZ35044.1 - 7.5e-47 159.9 0.0 9.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ35044.1 - 2.1e-29 102.6 0.0 2.8e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NHL PF01436.21 KEZ35044.1 - 1.9e-20 71.8 0.8 0.0017 18.3 0.0 6.1 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 KEZ35044.1 - 5.5e-12 45.8 1.1 4.9e-08 32.9 0.1 4.1 3 1 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 KEZ35044.1 - 1.9e-06 28.0 0.8 0.6 10.0 0.0 4.2 1 1 2 3 3 3 3 Esterase-like activity of phytase APH PF01636.23 KEZ35044.1 - 0.0041 17.1 1.6 0.028 14.3 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ35044.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FAD_binding_4 PF01565.23 KEZ35045.1 - 2.9e-28 98.3 4.6 2.9e-28 98.3 4.6 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEZ35045.1 - 1.5e-18 66.6 0.4 2.3e-18 66.0 0.4 1.3 1 0 0 1 1 1 1 Berberine and berberine like UCR_Fe-S_N PF10399.9 KEZ35045.1 - 1.9 7.9 5.9 0.29 10.5 0.8 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal NLPC_P60 PF00877.19 KEZ35047.1 - 4e-20 71.8 0.0 6.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family SLT PF01464.20 KEZ35047.1 - 1.8e-14 53.4 0.2 3e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 KEZ35047.1 - 3.3e-05 23.3 0.1 5.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Peptidase_C92 PF05708.12 KEZ35047.1 - 5.9e-05 23.2 0.0 0.0063 16.6 0.0 2.3 2 0 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Amidase_5 PF05382.13 KEZ35047.1 - 0.00053 19.9 0.9 0.0078 16.1 0.1 2.7 2 1 0 2 2 2 1 Bacteriophage peptidoglycan hydrolase Transglycosylas PF06737.14 KEZ35047.1 - 0.00085 19.9 0.6 0.0025 18.4 0.6 1.7 1 0 0 1 1 1 1 Transglycosylase-like domain CHAP PF05257.16 KEZ35047.1 - 0.0059 17.2 0.0 0.024 15.2 0.0 2.0 2 0 0 2 2 2 1 CHAP domain Phage_lysozyme2 PF18013.1 KEZ35047.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Phage tail lysozyme DEC-1_N PF04625.13 KEZ35048.1 - 0.2 10.7 6.3 0.25 10.3 6.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region HTH_17 PF12728.7 KEZ35049.1 - 5.6e-10 39.2 0.5 7.4e-10 38.9 0.5 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrbC PF04956.13 KEZ35052.1 - 0.014 15.6 10.5 0.015 15.5 7.9 1.9 1 1 1 2 2 2 0 TrbC/VIRB2 family PgaD PF13994.6 KEZ35052.1 - 0.19 11.8 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein DUF3810 PF12725.7 KEZ35054.1 - 0.57 9.5 4.5 1.1 8.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) EccE PF11203.8 KEZ35055.1 - 0.0013 19.0 3.0 0.0013 19.0 3.0 2.9 3 1 0 3 3 3 1 Putative type VII ESX secretion system translocon, EccE DUF2892 PF11127.8 KEZ35055.1 - 0.19 11.8 6.0 0.54 10.3 6.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) PrgI PF12666.7 KEZ35055.1 - 0.45 11.3 2.6 1.2 9.9 2.6 1.6 1 0 0 1 1 1 0 PrgI family protein AAA_10 PF12846.7 KEZ35056.1 - 0.0018 17.3 0.0 0.049 12.6 0.0 2.2 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 KEZ35056.1 - 0.15 10.9 0.1 1.3 7.9 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 KEZ35056.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Pentapeptide_3 PF13576.6 KEZ35056.1 - 0.81 9.9 13.9 1.5 9.0 13.9 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) PBP PF01161.20 KEZ35057.1 - 9.6e-36 123.0 0.0 1.2e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein P-II PF00543.22 KEZ35058.1 - 3.9e-26 91.6 0.2 4.3e-26 91.5 0.2 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II HisG_C PF08029.11 KEZ35058.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 HisG, C-terminal domain SNARE_assoc PF09335.11 KEZ35059.1 - 7.4e-22 78.1 1.6 1.6e-21 77.0 1.6 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Pam17 PF08566.10 KEZ35059.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 LIP PF03583.14 KEZ35060.1 - 5.2e-25 88.3 0.0 8.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 KEZ35060.1 - 1e-09 38.0 0.2 2.2e-09 37.0 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEZ35060.1 - 5.9e-08 32.4 0.2 0.011 15.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KEZ35060.1 - 2.4e-07 31.6 15.2 2.4e-07 31.6 15.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ35060.1 - 0.00061 19.5 0.0 0.0098 15.6 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Cutinase PF01083.22 KEZ35060.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase OsmC PF02566.19 KEZ35061.1 - 4e-17 62.5 0.0 5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein GntR PF00392.21 KEZ35062.1 - 7.7e-14 51.1 0.3 1.4e-13 50.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family peroxidase PF00141.23 KEZ35063.1 - 4.4e-88 294.8 0.0 9.9e-48 162.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase LysR_substrate PF03466.20 KEZ35064.1 - 4.1e-44 150.4 11.6 4.1e-44 150.4 11.6 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 KEZ35064.1 - 6.6e-18 64.4 3.9 6.6e-18 64.4 3.9 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 KEZ35064.1 - 0.062 13.1 2.6 0.11 12.3 0.5 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HSP20 PF00011.21 KEZ35066.1 - 1.4e-22 79.7 0.2 1.7e-22 79.5 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEZ35066.1 - 2.5e-10 39.7 1.0 4.6e-10 38.9 1.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KEZ35066.1 - 0.00019 22.4 0.0 0.00028 21.8 0.0 1.2 1 0 0 1 1 1 1 CS domain HMA PF00403.26 KEZ35066.1 - 0.032 14.7 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal-associated domain Sulfotransfer_4 PF17784.1 KEZ35067.1 - 4.6e-64 216.2 0.0 5.3e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ35067.1 - 0.0012 19.3 0.7 0.0046 17.4 0.1 2.1 1 1 0 2 2 2 1 Sulfotransferase family SE PF08491.10 KEZ35068.1 - 0.033 13.2 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 KEZ35068.1 - 0.068 12.0 0.0 6.7 5.4 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Rubrerythrin PF02915.17 KEZ35069.1 - 0.00032 21.1 0.6 0.0037 17.7 0.1 2.3 2 1 1 3 3 3 1 Rubrerythrin FA_desaturase_2 PF03405.14 KEZ35070.1 - 2.3e-17 62.8 0.1 2.9e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Ferritin PF00210.24 KEZ35070.1 - 4.2e-06 26.7 0.4 8.2e-06 25.8 0.4 1.5 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KEZ35070.1 - 4.1e-05 24.0 0.2 0.002 18.5 0.0 2.5 2 1 0 2 2 2 1 Rubrerythrin CMAS PF02353.20 KEZ35071.1 - 6.9e-43 146.9 0.0 8.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KEZ35071.1 - 2.8e-14 53.6 0.0 6.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ35071.1 - 8.3e-14 52.0 0.0 1.6e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35071.1 - 3.8e-13 49.6 0.0 5.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ35071.1 - 1.8e-09 37.6 0.0 2.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35071.1 - 6.4e-08 33.2 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ35071.1 - 4.7e-07 29.4 0.0 9.3e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ35071.1 - 0.00036 20.1 0.0 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KEZ35071.1 - 0.00096 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KEZ35071.1 - 0.0016 17.5 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KEZ35071.1 - 0.0043 16.8 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Antibiotic_NAT PF02522.14 KEZ35071.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase PP-binding PF00550.25 KEZ35072.1 - 3.2e-15 56.2 0.8 3.8e-15 56.0 0.8 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PEP-utilizers PF00391.23 KEZ35072.1 - 0.056 13.2 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain 4HBT PF03061.22 KEZ35073.1 - 4.9e-05 23.6 2.4 0.00017 21.9 0.7 2.2 2 0 0 2 2 2 1 Thioesterase superfamily AMP-binding PF00501.28 KEZ35074.1 - 5.5e-61 206.4 0.0 7.2e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 KEZ35074.1 - 0.0049 17.2 0.0 0.39 11.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain p450 PF00067.22 KEZ35075.1 - 3.3e-27 95.3 0.0 7.5e-25 87.6 0.0 2.8 2 1 0 2 2 2 1 Cytochrome P450 LysR_substrate PF03466.20 KEZ35076.1 - 4e-26 91.7 4.6 4e-26 91.7 4.6 1.7 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 KEZ35076.1 - 2.8e-20 72.0 1.1 2.8e-20 72.0 1.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 KEZ35076.1 - 0.0072 16.2 0.2 0.031 14.2 0.2 2.1 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.6 KEZ35076.1 - 0.055 13.3 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain AMP-binding PF00501.28 KEZ35077.1 - 4.2e-85 285.9 0.2 5.6e-85 285.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ35077.1 - 0.022 15.7 0.4 0.12 13.4 0.2 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 KEZ35079.1 - 1.6e-54 185.2 2.9 1.6e-54 185.2 2.9 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ35079.1 - 2e-32 111.6 2.8 4.4e-32 110.6 2.8 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KEZ35079.1 - 1e-06 28.3 2.0 2.8e-06 26.9 0.5 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KEZ35079.1 - 0.11 12.4 5.1 7.5 6.5 0.9 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_Tnp_1 PF01527.20 KEZ35080.1 - 0.036 14.4 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Transposase CMD PF02627.20 KEZ35080.1 - 0.11 12.5 3.5 0.14 12.2 1.2 1.9 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family DUF4389 PF14333.6 KEZ35081.1 - 6.1e-18 64.5 19.7 1.6e-11 43.9 5.1 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4389) CobS PF02654.15 KEZ35081.1 - 4.1 7.6 8.7 0.44 10.7 3.5 1.8 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase HypA PF01155.19 KEZ35082.1 - 1.2e-29 102.6 0.0 1.4e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KEZ35082.1 - 0.089 12.9 0.4 0.17 12.1 0.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain cobW PF02492.19 KEZ35083.1 - 3.6e-31 108.1 0.0 4.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KEZ35083.1 - 0.0031 17.4 0.0 0.019 14.8 0.0 2.1 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KEZ35083.1 - 0.0032 17.6 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEZ35083.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 KEZ35083.1 - 0.017 15.6 0.1 0.029 14.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ35083.1 - 0.042 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 KEZ35083.1 - 0.044 14.2 0.1 0.073 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KEZ35083.1 - 0.058 13.8 0.0 0.095 13.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ35083.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ35083.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KEZ35083.1 - 0.095 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KEZ35083.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 KEZ35083.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ35083.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KEZ35083.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.12 KEZ35083.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KEZ35083.1 - 0.22 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CENP-F_C_Rb_bdg PF10490.9 KEZ35084.1 - 0.027 13.9 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 HycI PF01750.18 KEZ35085.1 - 5.4e-11 42.4 0.0 8.2e-05 22.4 0.2 2.0 2 0 0 2 2 2 2 Hydrogenase maturation protease Oxidored_q6 PF01058.22 KEZ35086.1 - 1e-26 93.3 0.1 2.4e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 KEZ35086.1 - 1.8e-22 79.5 3.4 3e-22 78.8 3.4 1.4 1 0 0 1 1 1 1 NiFe/NiFeSe hydrogenase small subunit C-terminal NiFeSe_Hases PF00374.19 KEZ35087.1 - 1.2e-62 212.4 0.0 3.7e-43 148.2 0.0 2.1 1 1 1 2 2 2 2 Nickel-dependent hydrogenase NifU PF01106.17 KEZ35088.1 - 1.2e-09 38.1 0.1 1.8e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Sua5_yciO_yrdC PF01300.18 KEZ35091.1 - 8.3e-47 159.0 0.0 1.3e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination zf-HYPF PF07503.12 KEZ35091.1 - 4.7e-34 115.9 16.8 4.5e-17 61.5 3.6 2.5 2 0 0 2 2 2 2 HypF finger HypF_C PF17788.1 KEZ35091.1 - 3.2e-29 101.6 0.2 6.5e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 HypF Kae1-like domain Acylphosphatase PF00708.18 KEZ35091.1 - 1.7e-18 66.8 0.0 3.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Acylphosphatase TF_Zn_Ribbon PF08271.12 KEZ35091.1 - 0.16 11.5 6.9 3 7.4 1.2 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 KEZ35091.1 - 0.17 12.0 8.6 6.4 6.9 8.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KEZ35091.1 - 0.33 11.1 9.6 2.4 8.3 0.4 3.6 2 1 1 3 3 3 0 Zinc ribbon domain Lar_restr_allev PF14354.6 KEZ35091.1 - 0.45 10.9 1.6 19 5.7 0.1 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar TniQ PF06527.11 KEZ35091.1 - 2.4 8.9 9.2 18 6.0 0.3 3.5 3 1 1 4 4 4 0 TniQ HupF_HypC PF01455.18 KEZ35092.1 - 7.4e-19 67.7 0.1 9.5e-19 67.3 0.1 1.2 1 0 0 1 1 1 1 HupF/HypC family HypD PF01924.16 KEZ35093.1 - 1.3e-150 501.4 0.0 1.5e-150 501.2 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family AIRS_C PF02769.22 KEZ35094.1 - 2.9e-28 98.9 0.5 5e-28 98.2 0.5 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KEZ35094.1 - 2.5e-14 53.7 2.9 2.5e-14 53.7 2.9 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CSD PF00313.22 KEZ35095.1 - 1.5e-11 44.0 0.0 3e-11 43.0 0.0 1.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KEZ35095.1 - 0.001 18.7 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain DDE_Tnp_1_assoc PF13808.6 KEZ35096.1 - 8.5e-11 41.7 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 DDE_Tnp_1-associated CTV_P33 PF07184.11 KEZ35097.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.0 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein Phage_Coat_Gp8 PF05371.12 KEZ35098.1 - 0.053 13.3 0.2 0.071 12.9 0.2 1.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 NUDIX PF00293.28 KEZ35099.1 - 2.3e-19 69.7 0.1 2.9e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain HTH_31 PF13560.6 KEZ35100.1 - 0.00091 19.5 0.3 0.00091 19.5 0.3 3.1 2 0 0 2 2 2 1 Helix-turn-helix domain TPR_12 PF13424.6 KEZ35100.1 - 0.0099 16.2 7.7 0.058 13.7 1.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat HTH_3 PF01381.22 KEZ35100.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix TPR_2 PF07719.17 KEZ35100.1 - 0.15 12.3 0.4 1e+02 3.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ35100.1 - 0.3 12.0 14.6 0.89 10.5 0.9 4.5 2 2 2 4 4 4 0 Tetratricopeptide repeat HAD PF12710.7 KEZ35101.1 - 3.6e-16 60.1 0.4 9e-16 58.8 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ35101.1 - 1.9e-12 47.6 0.0 3.7e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ35101.1 - 1.9e-11 43.8 0.6 4.5e-11 42.7 0.6 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEZ35101.1 - 0.0024 18.2 2.9 0.017 15.4 1.6 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_2 PF07719.17 KEZ35102.1 - 0.00011 22.1 5.2 0.29 11.4 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ35102.1 - 0.003 17.8 10.3 0.87 9.9 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ35102.1 - 0.0055 17.2 0.5 0.0055 17.2 0.5 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ35102.1 - 0.011 15.9 0.3 3.8 8.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_3 PF01381.22 KEZ35102.1 - 0.014 15.5 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix TPR_6 PF13174.6 KEZ35102.1 - 0.045 14.4 7.1 1.3 9.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DZR PF12773.7 KEZ35102.1 - 0.049 13.7 2.2 0.12 12.4 2.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon ANAPC3 PF12895.7 KEZ35102.1 - 0.065 13.5 1.5 0.74 10.1 0.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KEZ35102.1 - 0.21 11.5 0.6 33 4.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ35102.1 - 0.29 10.5 9.7 0.44 9.9 2.9 2.3 1 1 1 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 KEZ35102.1 - 2.2 9.2 27.2 1 10.2 1.4 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Resolvase PF00239.21 KEZ35104.1 - 5.5e-06 26.5 0.0 6.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain DUF768 PF05589.11 KEZ35104.1 - 0.035 14.1 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF768) HhH-GPD PF00730.25 KEZ35106.1 - 0.0054 17.2 0.0 0.009 16.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Radical_SAM PF04055.21 KEZ35107.1 - 8.3e-19 68.6 0.0 1.3e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 KEZ35107.1 - 9.5e-09 35.3 0.3 2.7e-08 33.9 0.3 1.8 1 0 0 1 1 1 1 B12 binding domain DUF3432 PF11914.8 KEZ35107.1 - 0.96 9.7 5.4 1.7 8.9 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) FMN_red PF03358.15 KEZ35109.1 - 2e-05 24.4 0.0 3.1e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEZ35109.1 - 0.036 13.8 0.0 0.061 13.0 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin-like fold Multi_Drug_Res PF00893.19 KEZ35110.1 - 5.3e-22 78.3 8.0 6.8e-22 77.9 8.0 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 KEZ35110.1 - 0.072 13.3 10.6 0.086 13.0 10.6 1.2 1 0 0 1 1 1 0 EamA-like transporter family DUF5381 PF17353.2 KEZ35110.1 - 0.22 11.3 2.3 0.18 11.5 1.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5381) DUF3792 PF12670.7 KEZ35113.1 - 0.002 18.3 1.9 0.002 18.3 1.9 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3792) FAD_binding_3 PF01494.19 KEZ35114.1 - 9e-46 156.7 0.3 4.4e-45 154.5 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KEZ35114.1 - 4.6e-06 26.0 4.0 0.0024 17.0 0.1 2.8 3 1 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 KEZ35114.1 - 0.00017 20.6 0.1 0.034 13.0 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KEZ35114.1 - 0.00021 20.1 0.1 0.00031 19.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ35114.1 - 0.0003 21.0 0.1 0.00081 19.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ35114.1 - 0.0037 16.6 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ35114.1 - 0.0099 15.1 0.2 0.035 13.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ35114.1 - 0.02 15.4 0.1 0.041 14.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AIM24 PF01987.17 KEZ35115.1 - 2.6e-27 95.9 1.3 3.8e-27 95.4 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 KEZ35116.1 - 3.9e-33 114.9 0.2 4.6e-33 114.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 TerD PF02342.18 KEZ35117.1 - 2.5e-32 111.9 0.0 8.7e-32 110.1 0.0 1.7 2 0 0 2 2 2 1 TerD domain AIM24 PF01987.17 KEZ35117.1 - 9.3e-25 87.6 1.4 1.7e-24 86.7 1.4 1.4 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aldo_ket_red PF00248.21 KEZ35118.1 - 3e-60 203.9 0.0 3.5e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Proteasome PF00227.26 KEZ35119.1 - 0.046 13.2 0.1 7.1 6.1 0.1 2.2 2 0 0 2 2 2 0 Proteasome subunit Spo0M PF07070.11 KEZ35120.1 - 1.2e-75 253.6 0.1 1.4e-75 253.4 0.1 1.0 1 0 0 1 1 1 1 SpoOM protein Acetyltransf_1 PF00583.25 KEZ35121.1 - 3.8e-10 40.0 0.1 4.2e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ35121.1 - 5.1e-05 23.6 0.1 6.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ35121.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S9 PF00326.21 KEZ35122.1 - 3.9e-44 150.6 0.0 6.2e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEZ35122.1 - 1.1e-09 37.9 0.3 7.4e-05 22.1 0.3 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 KEZ35122.1 - 8.5e-07 28.7 0.6 1.5e-06 27.8 0.6 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S15 PF02129.18 KEZ35122.1 - 1.9e-06 27.7 0.0 0.00055 19.6 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KEZ35122.1 - 1.5e-05 24.8 0.0 0.0058 16.3 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KEZ35122.1 - 2.6e-05 23.9 0.0 0.00019 21.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KEZ35122.1 - 2.8e-05 24.1 0.2 9.6e-05 22.3 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KEZ35122.1 - 0.00013 20.7 0.1 0.027 13.1 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) ASFV_J13L PF05568.11 KEZ35122.1 - 0.0017 18.1 1.8 0.004 16.9 1.8 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein Abhydrolase_4 PF08386.10 KEZ35122.1 - 0.032 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein BAAT_C PF08840.11 KEZ35122.1 - 0.038 13.9 0.0 2 8.3 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KEZ35122.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Asn_synthase PF00733.21 KEZ35123.1 - 2.6e-79 267.5 0.0 3.3e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KEZ35123.1 - 7.7e-43 145.3 0.0 1.2e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KEZ35123.1 - 1.3e-37 129.0 0.0 2.1e-36 125.1 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain tRNA_Me_trans PF03054.16 KEZ35123.1 - 0.21 10.3 0.1 0.36 9.6 0.1 1.3 1 0 0 1 1 1 0 tRNA methyl transferase CP_ATPgrasp_2 PF14403.6 KEZ35124.1 - 2.5e-131 438.1 0.0 4.6e-131 437.2 0.0 1.5 2 0 0 2 2 2 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 KEZ35124.1 - 6.9e-99 331.0 0.1 1.5e-98 329.9 0.0 1.6 2 0 0 2 2 2 1 A circularly permuted ATPgrasp GCS2 PF04107.13 KEZ35124.1 - 6e-54 183.3 0.5 1.3e-53 182.3 0.2 1.6 2 0 0 2 2 2 1 Glutamate-cysteine ligase family 2(GCS2) ATPgrasp_YheCD PF14398.6 KEZ35124.1 - 0.11 11.7 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 KEZ35124.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain LDcluster4 PF18306.1 KEZ35125.1 - 5.4e-12 45.6 0.0 5.4e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 KEZ35125.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.2 1 1 0 1 1 1 0 Possible lysine decarboxylase Glu_synthase PF01645.17 KEZ35127.1 - 1.3e-82 277.9 3.4 1.7e-82 277.5 3.4 1.0 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 KEZ35127.1 - 0.0045 16.1 0.6 0.0045 16.1 0.6 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase 3-dmu-9_3-mt PF06983.13 KEZ35128.1 - 5.1e-46 156.0 0.0 6.2e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Bac_surface_Ag PF01103.23 KEZ35128.1 - 0.024 14.1 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Surface antigen DUF2158 PF09926.9 KEZ35128.1 - 1.1 9.1 3.1 7.2 6.4 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized small protein (DUF2158) GT87 PF09594.10 KEZ35130.1 - 2.2e-51 174.9 41.1 2.2e-51 174.9 41.1 3.3 3 1 0 3 3 3 1 Glycosyltransferase family 87 CDP-OH_P_transf PF01066.21 KEZ35130.1 - 0.34 11.7 0.0 0.34 11.7 0.0 3.2 2 2 0 2 2 2 0 CDP-alcohol phosphatidyltransferase SBP_bac_11 PF13531.6 KEZ35132.1 - 3.4e-20 72.8 2.8 3.4e-20 72.8 2.8 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein VWA PF00092.28 KEZ35132.1 - 7.7e-12 45.8 0.0 1.2e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KEZ35132.1 - 7.6e-09 35.7 0.0 3.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 KEZ35132.1 - 2.8e-07 31.1 0.0 8.6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KEZ35132.1 - 0.00016 21.1 0.3 0.0011 18.5 0.3 2.0 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein SBP_bac_6 PF13343.6 KEZ35132.1 - 0.041 13.3 0.0 0.078 12.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein TelA PF05816.11 KEZ35133.1 - 3.3e-90 302.5 0.4 3.8e-90 302.3 0.4 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) CDRN PF05174.12 KEZ35133.1 - 0.062 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus STAT_alpha PF01017.20 KEZ35133.1 - 0.073 13.0 0.2 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Spc7 PF08317.11 KEZ35133.1 - 0.12 11.2 0.9 2.1 7.2 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SBP_bac_11 PF13531.6 KEZ35134.1 - 1.3e-05 25.1 2.2 1.7e-05 24.6 2.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DDE_Tnp_1 PF01609.21 KEZ35135.1 - 4.3e-07 29.8 0.2 4.9e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain CstA PF02554.14 KEZ35136.1 - 1.7e-162 540.6 23.8 1.7e-162 540.6 23.8 2.1 2 0 0 2 2 2 1 Carbon starvation protein CstA CstA_5TM PF13722.6 KEZ35136.1 - 3.8e-32 111.1 7.3 3.8e-32 111.1 7.3 3.3 3 0 0 3 3 3 2 5TM C-terminal transporter carbon starvation CstA DUF3311 PF11755.8 KEZ35138.1 - 1.9e-20 72.5 2.6 3.1e-20 71.9 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) Sigma70_r4_2 PF08281.12 KEZ35140.1 - 4.5e-17 61.5 0.2 1.2e-16 60.1 0.2 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ35140.1 - 7.4e-12 44.6 0.1 2.6e-11 42.8 0.1 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 KEZ35140.1 - 0.00018 21.0 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 KEZ35140.1 - 0.0011 18.9 0.7 0.0051 16.7 0.7 2.0 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r2 PF04542.14 KEZ35140.1 - 0.0046 16.7 0.6 0.01 15.6 0.6 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 DUF134 PF02001.16 KEZ35140.1 - 0.02 15.4 0.1 0.056 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF134 UPF0122 PF04297.14 KEZ35140.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DUF3040 PF11239.8 KEZ35141.1 - 0.016 15.5 1.8 0.029 14.6 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) GRA6 PF05084.13 KEZ35141.1 - 0.083 12.8 0.1 0.083 12.8 0.1 1.1 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Thiolase_N PF00108.23 KEZ35142.1 - 9.4e-18 64.5 0.5 9.8e-17 61.2 0.1 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ35142.1 - 6.9e-10 38.6 0.1 4.3e-09 36.1 0.1 2.2 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KEZ35142.1 - 0.00011 21.9 0.4 0.0019 18.0 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KEZ35142.1 - 0.00053 19.6 4.4 0.0022 17.6 1.1 2.2 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ35142.1 - 0.002 18.1 0.1 0.35 10.9 0.0 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain DSBA PF01323.20 KEZ35142.1 - 0.0046 16.8 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 DSBA-like thioredoxin domain TetR_N PF00440.23 KEZ35143.1 - 8.5e-22 76.7 0.0 3.1e-12 46.1 0.0 2.8 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KEZ35143.1 - 1.2e-08 35.2 2.8 7.9e-05 22.9 0.5 2.5 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_C_30 PF17939.1 KEZ35143.1 - 0.015 15.5 7.5 1.4 9.1 0.9 3.4 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 KEZ35143.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 KEZ35143.1 - 1.5 9.6 20.4 0.12 13.1 2.8 3.1 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PRIMA1 PF16101.5 KEZ35143.1 - 5.3 7.1 6.1 9.2 6.3 6.1 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ABC-3 PF00950.17 KEZ35144.1 - 4.4e-35 121.4 22.8 5.2e-35 121.2 22.8 1.0 1 0 0 1 1 1 1 ABC 3 transport family ABC-3 PF00950.17 KEZ35145.1 - 1.8e-38 132.5 29.7 2.2e-38 132.3 29.7 1.1 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 KEZ35145.1 - 0.0019 17.3 33.7 0.0023 17.0 33.1 1.4 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 KEZ35146.1 - 2.6e-26 92.8 0.0 3.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ35146.1 - 3.7e-12 46.7 0.6 1.6e-05 24.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ35146.1 - 7.3e-06 25.6 0.0 0.046 13.2 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KEZ35146.1 - 7.7e-06 26.1 0.1 0.00045 20.4 0.0 3.0 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KEZ35146.1 - 3.4e-05 24.3 0.4 9.4e-05 22.8 0.3 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ35146.1 - 0.00061 20.1 0.1 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ35146.1 - 0.00063 19.4 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ35146.1 - 0.012 16.1 0.1 0.017 15.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ35146.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KEZ35146.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ35146.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KEZ35146.1 - 0.037 13.7 0.4 0.079 12.7 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ35146.1 - 0.04 13.5 3.5 1.4 8.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KEZ35146.1 - 0.049 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ35146.1 - 0.057 13.3 0.4 0.8 9.6 0.1 2.1 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 KEZ35146.1 - 0.075 11.8 0.9 6.4 5.5 0.1 2.6 2 1 1 3 3 3 0 Predicted ATPase of the ABC class MeaB PF03308.16 KEZ35146.1 - 0.091 11.7 0.5 0.13 11.3 0.5 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KEZ35146.1 - 0.2 11.4 0.3 0.53 10.0 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KEZ35146.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEZ35146.1 - 0.25 10.5 0.4 0.4 9.8 0.1 1.4 2 0 0 2 2 2 0 NB-ARC domain ZnuA PF01297.17 KEZ35147.1 - 2.8e-32 112.2 0.0 3.5e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic MutL PF13941.6 KEZ35148.1 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 MutL protein PGA_cap PF09587.10 KEZ35150.1 - 2.4e-75 253.3 0.0 2.8e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DUF1298 PF06974.13 KEZ35151.1 - 5.7e-09 36.1 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 KEZ35151.1 - 0.00011 22.0 2.4 0.81 9.4 0.0 3.6 4 0 0 4 4 4 2 Wax ester synthase-like Acyl-CoA acyltransferase domain PDT PF00800.18 KEZ35152.1 - 6.5e-46 156.4 0.0 8e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KEZ35152.1 - 3.9e-05 23.3 0.0 9.4e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain 2-oxoacid_dh PF00198.23 KEZ35153.1 - 1e-65 221.5 0.0 1.3e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ35153.1 - 1.3e-17 63.3 0.2 2.3e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEZ35153.1 - 4e-14 52.7 1.3 2.6e-13 50.0 0.2 2.6 2 0 0 2 2 2 1 e3 binding domain GCV_H PF01597.19 KEZ35153.1 - 0.058 13.3 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein Transket_pyr PF02779.24 KEZ35154.1 - 6.3e-44 149.8 0.2 1.3e-43 148.7 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ35154.1 - 2.9e-37 127.3 0.0 4.5e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KEZ35154.1 - 0.0017 18.6 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II CPSase_L_D2 PF02786.17 KEZ35154.1 - 0.11 11.9 0.1 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain E1_dh PF00676.20 KEZ35155.1 - 8.6e-69 231.8 0.0 1e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEZ35155.1 - 1.5e-05 24.4 0.0 0.00016 21.0 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 KEZ35155.1 - 0.00054 19.0 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 KEZ35155.1 - 0.01 15.6 0.4 0.058 13.2 0.5 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cytochrom_B_N_2 PF13631.6 KEZ35157.1 - 6.1e-61 205.3 4.2 1.3e-60 204.3 4.2 1.5 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 KEZ35157.1 - 5.9e-30 104.5 12.9 3.4e-28 98.7 12.9 2.2 1 1 0 1 1 1 1 Cytochrome b/b6/petB DUF4405 PF14358.6 KEZ35157.1 - 0.0035 17.9 6.0 0.0035 17.9 6.0 3.8 3 2 0 3 3 3 1 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 KEZ35157.1 - 0.019 14.6 1.4 0.019 14.6 1.4 3.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Rieske PF00355.26 KEZ35158.1 - 2.3e-09 37.0 0.4 3.7e-09 36.4 0.4 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Asparaginase_II PF06089.12 KEZ35158.1 - 0.17 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 L-asparaginase II Toprim_C_rpt PF13368.6 KEZ35159.1 - 0.019 14.9 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Cyt_c_ox_IV PF12270.8 KEZ35160.1 - 1.9e-33 115.4 4.0 2.2e-33 115.2 4.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4131 PF13567.6 KEZ35160.1 - 0.0007 19.3 3.9 0.2 11.3 0.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 KEZ35160.1 - 0.0016 18.5 2.8 0.0016 18.5 2.8 2.1 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III PMP22_Claudin PF00822.20 KEZ35160.1 - 0.045 13.6 0.4 0.045 13.6 0.4 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Phage_holin_2_3 PF16080.5 KEZ35160.1 - 0.095 12.5 0.4 0.095 12.5 0.4 1.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 PhoR PF11808.8 KEZ35160.1 - 0.27 11.7 0.1 0.27 11.7 0.1 2.3 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR DUF2207 PF09972.9 KEZ35160.1 - 0.45 9.2 7.1 3 6.5 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) COX1 PF00115.20 KEZ35161.1 - 1.4e-145 485.5 59.0 1.6e-145 485.3 59.0 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I FixH PF05751.11 KEZ35161.1 - 2.7 8.0 4.1 0.84 9.6 0.5 2.0 2 0 0 2 2 2 0 FixH Glyco_hydro_15 PF00723.21 KEZ35163.1 - 6.8e-26 91.0 0.0 1.6e-21 76.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPR_2 PF07719.17 KEZ35163.1 - 0.0037 17.3 1.3 0.016 15.3 1.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ35163.1 - 0.0039 17.5 0.8 0.027 14.8 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ35163.1 - 0.0039 17.7 1.6 0.0039 17.7 1.6 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ35163.1 - 0.0083 16.0 0.8 0.042 13.7 0.8 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ35163.1 - 0.026 15.1 0.1 0.026 15.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ35163.1 - 0.039 14.8 0.1 0.039 14.8 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ35163.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEZ35163.1 - 0.087 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KEZ35163.1 - 0.33 11.1 3.0 0.54 10.4 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.18 KEZ35164.1 - 1.3e-46 158.3 0.1 5.7e-46 156.3 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ35164.1 - 9.3e-27 93.4 0.1 1.9e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KEZ35164.1 - 2.4e-22 79.4 0.0 7.1e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KEZ35164.1 - 2.1e-06 27.7 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg B12-binding PF02310.19 KEZ35165.1 - 5.9e-20 71.5 0.1 1.1e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 KEZ35165.1 - 3e-15 57.0 0.0 1.6e-14 54.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily ATX_III PF08098.11 KEZ35165.1 - 0.12 12.4 1.6 0.22 11.6 1.6 1.4 1 0 0 1 1 1 0 Anemonia sulcata toxin III family Fer4_12 PF13353.6 KEZ35165.1 - 0.13 12.5 0.0 8.2 6.7 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain Caa3_CtaG PF09678.10 KEZ35166.1 - 9.1e-61 205.3 30.0 7.4e-60 202.3 28.0 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF4231 PF14015.6 KEZ35166.1 - 2.1 8.9 4.1 1.7 9.1 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Dyp_perox PF04261.12 KEZ35167.1 - 1.5e-83 280.5 0.0 1.8e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family PT PF04886.12 KEZ35167.1 - 0.0002 20.9 7.3 0.00078 18.9 7.3 2.1 1 0 0 1 1 1 1 PT repeat SCO1-SenC PF02630.14 KEZ35168.1 - 2.8e-25 88.8 0.0 3.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KEZ35168.1 - 0.028 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family MarR PF01047.22 KEZ35169.1 - 1.5e-15 56.8 0.0 2.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KEZ35169.1 - 2.5e-13 49.7 0.7 2.5e-13 49.7 0.7 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KEZ35169.1 - 1.3e-05 25.6 0.1 3.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KEZ35169.1 - 5.2e-05 23.0 0.5 0.00026 20.7 0.2 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 KEZ35169.1 - 7.5e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KEZ35169.1 - 0.0039 17.2 0.5 0.0094 16.0 0.2 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 KEZ35169.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 KEZ35169.1 - 0.051 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 KEZ35169.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain RP-C PF03428.13 KEZ35169.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.6 2 1 0 2 2 2 0 Replication protein C N-terminal domain Voltage_CLC PF00654.20 KEZ35170.1 - 1.8e-99 333.4 38.6 1.8e-99 333.4 38.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KEZ35170.1 - 6.6e-07 29.7 0.0 0.023 15.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain Thiolase_C PF02803.18 KEZ35171.1 - 0.0007 19.2 1.2 0.0007 19.2 1.2 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain TPR_20 PF14561.6 KEZ35172.1 - 7.3e-21 74.3 1.2 1.3e-19 70.4 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.20 KEZ35172.1 - 1.2e-20 73.4 0.0 1.7e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TPR_14 PF13428.6 KEZ35172.1 - 1.6e-05 25.3 1.6 1.6e-05 25.3 1.6 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ35172.1 - 0.00016 22.1 4.7 0.077 13.5 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 KEZ35172.1 - 0.00022 21.6 0.0 0.0046 17.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TPR_16 PF13432.6 KEZ35172.1 - 0.00082 20.0 18.4 0.00084 19.9 3.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 KEZ35172.1 - 0.0026 18.0 0.0 0.0069 16.7 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 KEZ35172.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Redoxin TPR_4 PF07721.14 KEZ35172.1 - 0.028 15.0 0.4 0.028 15.0 0.4 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat COX5B PF01215.19 KEZ35172.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb TPR_7 PF13176.6 KEZ35172.1 - 0.059 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat YfdX PF10938.8 KEZ35172.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 YfdX protein Thioredoxin_3 PF13192.6 KEZ35172.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.24 KEZ35172.1 - 0.12 12.6 0.0 0.37 11.1 0.0 1.8 1 1 1 2 2 2 0 Glutaredoxin Thioredoxin_7 PF13899.6 KEZ35172.1 - 0.17 12.1 0.2 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Thiamine_BP PF01910.17 KEZ35173.1 - 1e-29 102.2 0.1 1.2e-29 102.1 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 KEZ35173.1 - 0.0031 18.0 0.0 0.0042 17.5 0.0 1.1 1 0 0 1 1 1 1 YKOF-related Family TetR_C_31 PF17940.1 KEZ35173.1 - 0.029 14.6 4.8 0.55 10.5 1.3 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain L-fibroin PF05849.11 KEZ35173.1 - 0.043 13.1 0.0 0.094 12.0 0.0 1.5 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) HATPase_c PF02518.26 KEZ35174.1 - 4.3e-22 78.7 0.0 1.7e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ35174.1 - 1.1e-17 63.8 0.6 3e-17 62.4 0.6 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KEZ35174.1 - 3e-06 27.4 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.6 KEZ35174.1 - 0.00022 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KEZ35174.1 - 0.0063 16.5 0.1 0.094 12.7 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Prot_ATP_OB_N PF17758.1 KEZ35174.1 - 0.026 14.2 0.4 0.084 12.5 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain PAS_4 PF08448.10 KEZ35174.1 - 1.2 9.5 4.5 1.4 9.2 0.9 3.0 3 1 0 3 3 3 0 PAS fold Cupin_5 PF06172.11 KEZ35175.1 - 7.6e-42 142.8 0.0 8.8e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Thiolase_N PF00108.23 KEZ35176.1 - 4.5e-92 308.1 0.9 7e-92 307.5 0.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ35176.1 - 4.7e-39 132.8 2.4 1.6e-38 131.1 1.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEZ35176.1 - 0.00056 19.6 1.9 0.0015 18.2 1.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KEZ35176.1 - 0.0069 16.2 1.4 0.66 9.9 0.1 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KEZ35176.1 - 0.024 13.4 0.3 0.041 12.6 0.3 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF2148 PF09918.9 KEZ35176.1 - 0.15 12.1 3.8 0.31 11.1 2.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) VCBS PF13517.6 KEZ35177.1 - 0.00078 20.0 1.0 0.0025 18.4 1.0 2.0 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Sigma70_r4_2 PF08281.12 KEZ35178.1 - 3.3e-16 58.7 0.4 7.2e-16 57.6 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ35178.1 - 1.9e-09 36.9 0.0 4.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KEZ35178.1 - 5.9e-09 35.6 2.7 5.9e-09 35.6 2.7 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 KEZ35178.1 - 0.0012 18.7 3.0 0.082 12.8 3.0 2.1 1 1 0 1 1 1 1 ECF sigma factor DUF134 PF02001.16 KEZ35178.1 - 0.016 15.8 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_23 PF13384.6 KEZ35178.1 - 0.083 12.7 5.3 0.78 9.6 1.2 3.6 3 1 0 3 3 3 0 Homeodomain-like domain ADH_zinc_N PF00107.26 KEZ35179.1 - 4.8e-29 101.0 0.0 7.3e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ35179.1 - 5.2e-08 34.0 0.0 1.2e-07 32.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ35179.1 - 8.1e-06 25.7 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Baculo_PEP_C PF04513.12 KEZ35180.1 - 0.0027 17.7 1.0 0.0027 17.7 1.0 1.8 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DivIVA PF05103.13 KEZ35180.1 - 0.016 15.3 24.4 1.4 9.0 19.9 3.2 1 1 1 2 2 2 0 DivIVA protein Prefoldin PF02996.17 KEZ35180.1 - 0.017 15.0 1.0 0.017 15.0 1.0 2.7 2 1 0 3 3 3 0 Prefoldin subunit SOGA PF11365.8 KEZ35180.1 - 0.097 13.8 9.2 4.5 8.5 0.1 3.3 1 1 2 3 3 3 0 Protein SOGA EDR1 PF14381.6 KEZ35180.1 - 0.34 10.6 1.0 0.48 10.1 1.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 ApoO PF09769.9 KEZ35180.1 - 2.5 8.0 5.0 1.4 8.9 0.9 2.5 2 1 1 3 3 3 0 Apolipoprotein O Apolipoprotein PF01442.18 KEZ35180.1 - 3.9 7.3 36.4 13 5.6 36.4 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain vATP-synt_E PF01991.18 KEZ35180.1 - 6 6.2 17.7 13 5.1 17.5 1.7 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF1232 PF06803.12 KEZ35181.1 - 5.3e-11 42.1 0.0 8.4e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) 3HCDH_N PF02737.18 KEZ35182.1 - 1.1e-115 383.8 0.5 3.9e-59 199.6 0.2 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ35182.1 - 3.5e-66 219.9 0.2 2e-31 108.5 0.0 3.5 4 0 0 4 4 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain F420_oxidored PF03807.17 KEZ35182.1 - 8.3e-09 35.9 3.7 0.0021 18.6 0.3 2.8 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEZ35182.1 - 1.6e-07 31.6 4.0 0.00016 21.9 0.6 2.9 3 1 0 3 3 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KEZ35182.1 - 6.7e-07 29.1 3.2 0.0038 16.9 0.1 2.8 3 0 0 3 3 2 2 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KEZ35182.1 - 6.8e-07 28.8 0.6 0.0002 20.8 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KEZ35182.1 - 0.00018 21.5 0.4 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KEZ35182.1 - 0.00035 20.7 2.2 0.25 11.4 0.1 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KEZ35182.1 - 0.00037 20.7 2.9 0.0068 16.6 1.0 2.8 2 1 0 2 2 2 1 TrkA-N domain ThiF PF00899.21 KEZ35182.1 - 0.0028 17.0 2.1 0.023 14.1 0.1 2.4 2 0 0 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KEZ35182.1 - 0.0033 17.0 0.1 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KEZ35182.1 - 0.0044 17.4 4.0 0.05 14.0 0.6 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KEZ35182.1 - 0.0049 16.2 1.5 0.97 8.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DFP PF04127.15 KEZ35182.1 - 0.0068 16.2 5.3 0.43 10.4 0.6 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 KEZ35182.1 - 0.0078 15.7 2.7 1.1 8.7 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Pyr_redox PF00070.27 KEZ35182.1 - 0.023 15.3 4.2 2.5 8.7 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KEZ35182.1 - 0.031 14.5 6.2 1.1 9.6 0.2 2.8 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KEZ35182.1 - 0.042 13.4 4.5 1.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase AbiEi_4 PF13338.6 KEZ35182.1 - 0.093 12.9 2.5 3.3 7.9 0.4 3.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin IlvN PF07991.12 KEZ35182.1 - 0.11 12.1 1.1 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GntR PF00392.21 KEZ35182.1 - 0.17 11.5 1.3 5.2 6.8 0.1 3.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family FAD_binding_3 PF01494.19 KEZ35182.1 - 0.22 10.8 5.9 0.04 13.2 0.6 2.0 2 0 0 2 2 2 0 FAD binding domain Rossmann-like PF10727.9 KEZ35182.1 - 0.43 10.4 14.0 0.088 12.7 0.7 3.2 3 1 0 3 3 3 0 Rossmann-like domain NucS PF01939.16 KEZ35183.1 - 8.6e-72 241.2 0.0 1e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Endonuclease NucS UPF0102 PF02021.17 KEZ35183.1 - 0.039 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 ATPgrasp_YheCD PF14398.6 KEZ35183.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp HD_4 PF13328.6 KEZ35184.1 - 3.8e-06 26.7 4.7 3.8e-06 26.7 4.7 1.6 1 1 1 2 2 2 1 HD domain HD PF01966.22 KEZ35184.1 - 0.00011 22.4 2.1 0.00053 20.2 2.1 2.0 1 1 0 1 1 1 1 HD domain ATPase_gene1 PF09527.10 KEZ35185.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter STAS_2 PF13466.6 KEZ35186.1 - 1e-14 54.6 7.0 1.4e-14 54.2 6.7 1.3 1 1 0 1 1 1 1 STAS domain STAS PF01740.21 KEZ35186.1 - 0.005 16.5 0.0 0.0064 16.1 0.0 1.1 1 0 0 1 1 1 1 STAS domain EPSP_synthase PF00275.20 KEZ35188.1 - 5.6e-91 305.3 0.7 6.3e-91 305.1 0.7 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF3188 PF11384.8 KEZ35189.1 - 0.076 12.7 1.3 0.15 11.8 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) PP2C_2 PF13672.6 KEZ35190.1 - 2.3e-08 33.9 0.1 1.4e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Cob_adeno_trans PF01923.18 KEZ35191.1 - 8.3e-57 191.9 0.0 9.3e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase ATP-synt_DE_N PF02823.16 KEZ35193.1 - 3.8e-27 94.0 0.2 4.2e-27 93.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_ab PF00006.25 KEZ35194.1 - 9e-62 208.5 0.0 1.2e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEZ35194.1 - 1.1e-21 77.1 0.3 2.7e-21 75.8 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KEZ35194.1 - 0.0018 18.2 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KEZ35194.1 - 0.0034 17.8 0.1 0.069 13.6 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEZ35194.1 - 0.013 15.8 0.9 0.095 13.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 KEZ35194.1 - 0.027 14.3 1.4 0.13 12.1 1.4 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 KEZ35194.1 - 0.11 11.8 1.3 0.29 10.4 1.3 1.7 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KEZ35194.1 - 0.11 12.8 0.2 0.4 11.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KEZ35194.1 - 0.17 11.0 0.3 0.33 10.1 0.3 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KEZ35194.1 - 0.2 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEZ35194.1 - 0.23 11.9 0.0 0.7 10.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase ATP-synt PF00231.19 KEZ35195.1 - 6.4e-91 304.9 0.2 7.1e-91 304.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase CbiJ PF02571.14 KEZ35195.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Adeno_PVIII PF01310.18 KEZ35195.1 - 0.013 15.1 0.3 0.019 14.6 0.3 1.3 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII OrfB_IS605 PF01385.19 KEZ35195.1 - 0.044 14.0 3.7 0.56 10.4 0.2 2.3 2 0 0 2 2 2 0 Probable transposase DUF3349 PF11829.8 KEZ35195.1 - 1.3 9.8 3.4 3.3 8.6 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) ATP-synt_ab PF00006.25 KEZ35196.1 - 8.1e-69 231.5 0.0 1.1e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KEZ35196.1 - 1.5e-45 154.6 0.0 2.3e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KEZ35196.1 - 2.2e-11 44.1 4.7 2.2e-11 44.1 4.7 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KEZ35196.1 - 0.00084 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 KEZ35196.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEZ35196.1 - 0.061 13.4 0.0 0.74 9.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain OSCP PF00213.18 KEZ35197.1 - 1.3e-33 116.5 0.0 2.6e-29 102.5 0.0 2.0 2 0 0 2 2 2 2 ATP synthase delta (OSCP) subunit ATP-synt_B PF00430.18 KEZ35198.1 - 2.5e-25 89.1 19.2 3.2e-25 88.7 19.2 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 KEZ35198.1 - 0.078 12.6 2.3 0.36 10.4 2.0 1.9 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) V-ATPase_G_2 PF16999.5 KEZ35198.1 - 0.32 11.4 27.4 0.89 10.0 27.4 1.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 KEZ35198.1 - 0.38 11.1 11.5 0.56 10.5 11.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KEZ35198.1 - 0.4 9.5 5.1 0.52 9.1 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V-ATPase_G PF03179.15 KEZ35198.1 - 0.57 10.7 16.9 0.076 13.5 9.2 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4407 PF14362.6 KEZ35198.1 - 2.3 7.5 16.4 3.6 6.8 16.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 KEZ35198.1 - 5 7.5 8.4 8.3 6.8 8.0 1.5 1 1 0 1 1 1 0 YlqD protein Atg14 PF10186.9 KEZ35198.1 - 5.8 5.9 6.1 7.3 5.6 6.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_C PF00137.21 KEZ35199.1 - 5.8e-13 49.0 9.6 7.3e-13 48.7 9.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_A PF00119.20 KEZ35200.1 - 7.9e-52 176.3 14.6 9.7e-52 176.0 14.6 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATPase_gene1 PF09527.10 KEZ35201.1 - 5.6e-05 23.2 8.9 6.9e-05 22.9 8.9 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4191 PF13829.6 KEZ35201.1 - 0.35 10.2 1.5 0.37 10.1 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Phage_holin_3_1 PF05106.12 KEZ35202.1 - 1.6 9.3 7.5 14 6.2 2.4 2.1 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Glycos_transf_4 PF00953.21 KEZ35203.1 - 6.5e-35 120.5 12.3 6.5e-35 120.5 12.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 SHMT PF00464.19 KEZ35204.1 - 7.7e-158 525.3 0.0 9e-158 525.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KEZ35204.1 - 1e-07 31.6 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KEZ35204.1 - 1.2e-07 31.2 0.0 2.1e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEZ35204.1 - 5e-07 29.4 0.1 6.9e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.13 KEZ35204.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Cys_Met_Meta_PP PF01053.20 KEZ35204.1 - 0.058 11.9 0.0 0.088 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4142 PF13628.6 KEZ35204.1 - 0.23 11.7 1.7 0.5 10.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Sua5_yciO_yrdC PF01300.18 KEZ35205.1 - 8.6e-49 165.5 0.0 9.8e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination PrmC_N PF17827.1 KEZ35206.1 - 1.6e-17 63.8 2.4 2.8e-17 63.0 2.4 1.4 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 KEZ35206.1 - 1.2e-12 47.7 0.0 2.3e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KEZ35206.1 - 3.6e-08 33.4 0.0 5.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ35206.1 - 8.7e-08 32.8 0.0 8.4e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KEZ35206.1 - 2.6e-07 30.5 0.0 6.1e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KEZ35206.1 - 0.00017 22.2 0.1 0.087 13.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KEZ35206.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 KEZ35206.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KEZ35206.1 - 0.0076 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KEZ35206.1 - 0.018 15.8 0.0 0.26 12.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ35206.1 - 0.039 13.4 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KEZ35206.1 - 0.042 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DNA_methylase PF00145.17 KEZ35206.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF43 PF01861.16 KEZ35206.1 - 0.26 10.5 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain PCRF PF03462.18 KEZ35207.1 - 9.4e-62 208.3 0.0 1.9e-61 207.3 0.0 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KEZ35207.1 - 1.4e-37 128.2 1.7 1.6e-37 127.9 0.8 1.6 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 KEZ35207.1 - 6.5e-06 26.3 3.1 0.004 17.4 0.0 3.1 3 0 0 3 3 3 2 ABC transporter C-terminal domain MIR PF02815.19 KEZ35207.1 - 0.058 13.2 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 MIR domain PNKP-ligase_C PF16536.5 KEZ35207.1 - 0.34 11.2 5.3 2.5 8.4 0.3 2.6 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Ribosomal_L31 PF01197.18 KEZ35208.1 - 1e-32 112.1 1.2 1.2e-32 112.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 DUF1364 PF07102.12 KEZ35208.1 - 0.011 15.6 0.2 0.012 15.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) ADD_ATRX PF17981.1 KEZ35208.1 - 0.063 13.1 1.1 0.19 11.6 1.2 1.7 2 0 0 2 2 2 0 Cysteine Rich ADD domain Erythro-docking PF09277.11 KEZ35208.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Erythronolide synthase, docking Rho_RNA_bind PF07497.12 KEZ35209.1 - 1e-28 99.0 0.1 2.3e-28 97.9 0.1 1.6 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 KEZ35209.1 - 2.6e-22 79.5 0.1 4.2e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 KEZ35209.1 - 3.1e-10 39.8 0.1 1.1e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain NACHT PF05729.12 KEZ35209.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KEZ35209.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain HofP PF10748.9 KEZ35209.1 - 0.081 12.5 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 DNA utilization proteins HofP GHMP_kinases_N PF00288.26 KEZ35210.1 - 4.8e-10 39.5 1.1 4.8e-10 39.5 1.1 2.9 3 0 0 3 3 3 2 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEZ35210.1 - 0.00085 19.6 0.6 0.00085 19.6 0.6 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal PALP PF00291.25 KEZ35211.1 - 3e-71 240.2 5.8 3.5e-71 240.0 5.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.10 KEZ35211.1 - 0.003 17.7 0.3 0.7 10.1 0.0 3.6 4 0 0 4 4 4 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ATPgrasp_N PF18130.1 KEZ35211.1 - 0.09 13.3 0.2 34 5.1 0.1 2.9 2 1 1 3 3 3 0 ATP-grasp N-terminal domain Homoserine_dh PF00742.19 KEZ35212.1 - 1.1e-63 214.3 0.5 4.5e-63 212.3 0.2 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KEZ35212.1 - 1.7e-20 73.8 1.4 4.8e-20 72.4 0.4 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 KEZ35212.1 - 1.2e-11 44.1 0.2 3.5e-11 42.7 0.2 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KEZ35212.1 - 0.0085 16.1 0.3 0.031 14.3 0.1 2.0 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 KEZ35212.1 - 0.017 15.7 0.0 0.043 14.4 0.0 1.7 1 1 0 1 1 1 0 ACT domain PhageMin_Tail PF10145.9 KEZ35212.1 - 0.11 12.3 4.1 0.22 11.4 4.1 1.5 1 0 0 1 1 1 0 Phage-related minor tail protein Sacchrp_dh_NADP PF03435.18 KEZ35212.1 - 0.13 12.5 0.6 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ACT_7 PF13840.6 KEZ35212.1 - 0.35 10.7 1.7 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 ACT domain Orn_Arg_deC_N PF02784.16 KEZ35213.1 - 5e-61 206.2 0.0 6.4e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KEZ35213.1 - 1.3e-15 57.4 0.0 1.7e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KEZ35213.1 - 0.00049 19.8 0.6 0.00098 18.8 0.6 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Hexapep PF00132.24 KEZ35213.1 - 0.12 12.2 1.2 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) DALR_1 PF05746.15 KEZ35214.1 - 6.7e-35 119.8 0.0 1.1e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KEZ35214.1 - 1.6e-21 76.7 0.0 2.9e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Response_reg PF00072.24 KEZ35215.1 - 1.1e-28 99.6 0.9 1.2e-28 99.5 0.9 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_25 PF13649.6 KEZ35216.1 - 1.3e-15 57.8 0.0 2.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ35216.1 - 2.1e-14 53.9 0.0 3.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ35216.1 - 1.8e-12 47.3 0.0 2.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35216.1 - 5.7e-10 39.8 0.0 9.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35216.1 - 9e-09 35.4 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain VitK2_biosynth PF02621.14 KEZ35216.1 - 0.008 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Menaquinone biosynthesis ADH_zinc_N PF00107.26 KEZ35216.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrmA PF06325.13 KEZ35216.1 - 0.057 12.8 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KEZ35216.1 - 0.085 13.9 0.1 0.24 12.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ35216.1 - 0.16 11.5 0.0 0.82 9.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain GIIM PF08388.11 KEZ35217.1 - 2.9e-16 59.3 5.4 6.4e-16 58.2 5.4 1.7 1 1 0 1 1 1 1 Group II intron, maturase-specific domain CBM_48 PF02922.18 KEZ35219.1 - 2.2e-24 85.6 0.0 2.3e-19 69.5 0.0 2.6 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 KEZ35219.1 - 7e-21 74.5 0.0 1.3e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KEZ35219.1 - 1e-10 41.8 0.0 5e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KEZ35219.1 - 0.017 13.4 0.0 0.025 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Mak_N_cap PF18085.1 KEZ35220.1 - 1.6e-17 64.3 0.1 5.2e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Maltokinase N-terminal cap domain APH_6_hur PF04655.14 KEZ35220.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Alpha-amylase PF00128.24 KEZ35221.1 - 2.4e-75 254.2 0.0 6.1e-75 252.9 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KEZ35221.1 - 9.5e-27 92.9 0.0 1.8e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 KEZ35221.1 - 4.9e-05 23.6 0.2 0.00021 21.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) GHL5 PF14872.6 KEZ35221.1 - 0.045 11.8 0.0 0.25 9.3 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 DUF3416 PF11896.8 KEZ35222.1 - 2.5e-52 177.7 0.0 3.9e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Alpha-amylase PF00128.24 KEZ35222.1 - 7.1e-06 25.8 0.0 0.00016 21.4 0.0 2.1 1 1 1 2 2 2 1 Alpha amylase, catalytic domain GHL6 PF14871.6 KEZ35222.1 - 0.0012 19.0 0.0 0.0097 16.1 0.0 2.3 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 TerD PF02342.18 KEZ35223.1 - 1.3e-84 282.4 0.0 1.4e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 TerD domain DUF475 PF04332.15 KEZ35224.1 - 4.5e-118 394.3 6.7 6.7e-118 393.8 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF475) TerC PF03741.16 KEZ35224.1 - 6.5e-18 65.0 10.2 2.3e-16 60.0 10.2 2.5 1 1 0 1 1 1 1 Integral membrane protein TerC family DUF4530 PF15039.6 KEZ35226.1 - 0.062 13.4 0.2 0.14 12.3 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) HSP70 PF00012.20 KEZ35227.1 - 7.6e-93 311.7 3.9 2.8e-84 283.4 0.5 3.0 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KEZ35227.1 - 2.3e-13 49.7 0.3 1.1e-12 47.5 0.3 2.2 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KEZ35227.1 - 0.021 13.9 0.0 0.099 11.6 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; zf-ribbon_3 PF13248.6 KEZ35228.1 - 1.1e-06 27.8 9.6 0.00029 20.2 1.5 2.4 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KEZ35228.1 - 0.00048 20.1 11.8 0.00084 19.3 11.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 KEZ35228.1 - 0.0092 16.0 3.8 0.0092 16.0 3.8 2.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 FdhE PF04216.12 KEZ35228.1 - 0.01 15.7 1.7 0.01 15.7 1.7 2.0 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation zinc_ribbon_2 PF13240.6 KEZ35228.1 - 0.02 14.6 0.7 0.02 14.6 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_26 PF02156.15 KEZ35229.1 - 7.7e-08 32.1 0.6 1.6e-07 31.1 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 26 C-C_Bond_Lyase PF15617.6 KEZ35230.1 - 1.5e-129 432.0 0.0 1.7e-129 431.8 0.0 1.0 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold HpcH_HpaI PF03328.14 KEZ35230.1 - 0.00046 19.4 0.2 0.0014 17.9 0.3 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PRTase_2 PF15609.6 KEZ35231.1 - 3.9e-66 222.2 0.0 2.9e-65 219.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase TRSP PF12500.8 KEZ35231.1 - 7.1e-41 139.2 0.0 1.3e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 TRSP domain C terminus to PRTase_2 Pribosyltran PF00156.27 KEZ35231.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ35231.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_1 PF11202.8 KEZ35232.1 - 1.3e-99 332.5 0.0 1.6e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) PELOTA_1 PF15608.6 KEZ35232.1 - 6.3e-31 106.1 0.0 1.3e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 PELOTA RNA binding domain Hydrolase_3 PF08282.12 KEZ35233.1 - 0.0058 16.4 0.0 2 8.1 0.0 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DnaJ_CXXCXGXG PF00684.19 KEZ35235.1 - 0.00074 19.8 7.4 0.0014 19.0 7.4 1.6 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ35235.1 - 0.017 15.1 5.1 0.3 11.1 0.3 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein NADH-G_4Fe-4S_3 PF10588.9 KEZ35235.1 - 0.1 12.2 1.9 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1356 PF07092.12 KEZ35235.1 - 3.2 6.9 5.4 0.79 8.9 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) CBM_48 PF02922.18 KEZ35236.1 - 9.5e-16 57.9 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KEZ35236.1 - 9.5e-13 48.4 0.0 1.4e-06 28.1 0.0 2.9 2 1 0 3 3 3 2 Alpha amylase, catalytic domain DUF3417 PF11897.8 KEZ35237.1 - 9.2e-36 122.6 0.0 1.7e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3417) Phosphorylase PF00343.20 KEZ35237.1 - 1.4e-24 86.5 0.0 1.7e-13 49.8 0.0 3.6 3 1 0 3 3 3 3 Carbohydrate phosphorylase AMP-binding PF00501.28 KEZ35238.1 - 4.3e-86 289.1 0.0 5.9e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ35238.1 - 2e-26 92.7 2.7 2.6e-26 92.4 0.6 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KEZ35238.1 - 1.9e-18 66.1 0.4 3.7e-18 65.2 0.4 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AAA_16 PF13191.6 KEZ35238.1 - 1.3 9.3 4.0 3 8.2 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain ECH_1 PF00378.20 KEZ35240.1 - 2e-58 197.7 0.0 2.4e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ35240.1 - 5.3e-27 95.2 0.2 8.3e-26 91.3 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KEZ35240.1 - 0.11 12.4 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 Exo_endo_phos PF03372.23 KEZ35241.1 - 1.5e-15 57.4 1.6 2.8e-15 56.5 1.6 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KEZ35241.1 - 0.0028 17.5 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase ETF PF01012.21 KEZ35243.1 - 1.3e-47 162.0 8.7 1.8e-47 161.6 8.7 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SpaA PF17802.1 KEZ35243.1 - 0.038 14.3 0.2 0.18 12.1 0.0 2.1 2 1 0 2 2 2 0 Prealbumin-like fold domain ETF_alpha PF00766.19 KEZ35244.1 - 2e-37 127.1 1.2 2e-37 127.1 1.2 2.6 2 1 1 3 3 3 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 KEZ35244.1 - 9.1e-30 103.9 12.7 1.4e-29 103.3 12.7 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPP_enzyme_M PF00205.22 KEZ35244.1 - 0.0016 18.1 1.9 1.1 8.9 0.2 2.9 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PP2C_2 PF13672.6 KEZ35245.1 - 0.0049 16.5 0.1 0.0088 15.7 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3071 PF11268.8 KEZ35247.1 - 0.035 14.2 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) HTH_23 PF13384.6 KEZ35247.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF1616 PF07760.11 KEZ35247.1 - 0.29 10.5 0.0 0.29 10.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF3040 PF11239.8 KEZ35247.1 - 0.68 10.2 3.3 2.1 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DoxX_2 PF13564.6 KEZ35247.1 - 3.2 7.9 9.2 3.9 7.6 0.1 2.7 3 0 0 3 3 3 0 DoxX-like family APH PF01636.23 KEZ35248.1 - 4.6e-06 26.7 1.9 0.0016 18.4 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KEZ35248.1 - 0.00032 20.2 0.0 0.00044 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KEZ35248.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KEZ35248.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Helicase_C PF00271.31 KEZ35250.1 - 3.5e-20 72.4 0.0 9.4e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEZ35250.1 - 3.2e-14 52.4 0.0 5.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEZ35250.1 - 2.8e-10 40.5 0.0 5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ35250.1 - 2.1e-07 30.9 0.0 4.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KEZ35250.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 KEZ35250.1 - 0.013 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FlgN PF05130.12 KEZ35250.1 - 0.024 15.1 1.0 0.024 15.1 1.0 2.2 2 0 0 2 2 2 0 FlgN protein Helicase_RecD PF05127.14 KEZ35250.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Helicase Penicillinase_R PF03965.16 KEZ35250.1 - 0.052 13.9 0.6 3.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Penicillinase repressor AAA_34 PF13872.6 KEZ35250.1 - 0.071 12.0 0.0 0.27 10.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 AAA_22 PF13401.6 KEZ35250.1 - 0.08 13.2 0.4 0.71 10.1 0.1 2.8 2 1 1 3 3 3 0 AAA domain FAD_binding_4 PF01565.23 KEZ35251.1 - 3.4e-32 111.1 3.2 6.1e-32 110.2 2.8 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEZ35251.1 - 2.5e-10 40.3 0.9 4.7e-10 39.4 0.2 1.9 2 0 0 2 2 2 1 Berberine and berberine like DUF2397 PF09660.10 KEZ35252.1 - 2.4e-184 613.8 16.7 2.8e-184 613.6 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) baeRF_family10 PF18854.1 KEZ35252.1 - 0.1 12.9 4.5 0.12 12.6 1.7 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF2398 PF09661.10 KEZ35253.1 - 4.2e-114 381.6 24.9 4.8e-114 381.4 24.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2398) SbcCD_C PF13558.6 KEZ35254.1 - 2.6e-22 78.8 0.1 1.9e-21 76.1 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KEZ35254.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aminotran_1_2 PF00155.21 KEZ35254.1 - 0.16 11.1 2.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class I and II DUF3323 PF11796.8 KEZ35255.1 - 9.8e-55 185.7 14.1 1.6e-54 185.0 14.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) DUF2399 PF09664.10 KEZ35255.1 - 1.4e-53 180.9 0.0 2.9e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF2220 PF09983.9 KEZ35255.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) CarD_CdnL_TRCF PF02559.16 KEZ35256.1 - 0.0035 18.0 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 CarD-like/TRCF domain cobW PF02492.19 KEZ35257.1 - 2.7e-26 92.2 0.0 3.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KEZ35257.1 - 0.15 12.4 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain HypA PF01155.19 KEZ35258.1 - 6.2e-36 122.8 0.0 8.1e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 KEZ35258.1 - 0.15 12.0 1.2 0.25 11.3 1.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Oxidored_q6 PF01058.22 KEZ35259.1 - 1e-33 115.9 0.0 1.4e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 KEZ35259.1 - 1.2e-20 73.6 3.0 2.4e-20 72.7 3.0 1.4 1 0 0 1 1 1 1 NiFe/NiFeSe hydrogenase small subunit C-terminal NiFeSe_Hases PF00374.19 KEZ35260.1 - 2.1e-79 267.8 0.0 2e-58 198.5 0.0 2.6 2 1 0 2 2 2 2 Nickel-dependent hydrogenase HycI PF01750.18 KEZ35261.1 - 2.9e-12 46.5 0.0 4.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase maturation protease TPR_12 PF13424.6 KEZ35262.1 - 0.026 14.8 22.5 0.034 14.4 0.2 5.4 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ35262.1 - 0.28 10.9 4.1 51 3.7 0.1 4.3 3 1 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 KEZ35262.1 - 2 8.4 24.9 12 5.9 1.3 6.5 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ35262.1 - 6.1 6.8 5.3 9.7 6.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ35262.1 - 8 6.8 8.6 36 4.7 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat NHL PF01436.21 KEZ35263.1 - 1.1e-26 91.4 12.9 0.00057 19.8 0.3 6.5 6 0 0 6 6 6 6 NHL repeat VCX_VCY PF15231.6 KEZ35263.1 - 3.4 8.4 4.4 1.6 9.4 1.8 1.7 2 0 0 2 2 2 0 Variable charge X/Y family Sua5_yciO_yrdC PF01300.18 KEZ35264.1 - 1e-40 139.1 0.0 1.8e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination zf-HYPF PF07503.12 KEZ35264.1 - 4.7e-33 112.6 13.8 2.2e-16 59.3 4.8 2.5 2 0 0 2 2 2 2 HypF finger HypF_C PF17788.1 KEZ35264.1 - 3.2e-29 101.6 0.6 5.4e-29 100.9 0.6 1.4 1 0 0 1 1 1 1 HypF Kae1-like domain Acylphosphatase PF00708.18 KEZ35264.1 - 1.1e-18 67.4 0.1 1.9e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Acylphosphatase NMD3 PF04981.13 KEZ35264.1 - 0.033 13.6 2.8 0.35 10.3 0.4 2.1 1 1 0 2 2 2 0 NMD3 family Zn-ribbon_8 PF09723.10 KEZ35264.1 - 2 8.6 6.3 8.6 6.6 1.5 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 KEZ35264.1 - 2.2 8.0 6.3 7.1 6.4 0.1 3.1 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HupF_HypC PF01455.18 KEZ35265.1 - 1.2e-22 79.8 0.0 1.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 HupF/HypC family HypD PF01924.16 KEZ35266.1 - 2.2e-149 497.3 0.0 2.5e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family AIRS_C PF02769.22 KEZ35267.1 - 1.1e-28 100.3 3.6 1.1e-28 100.3 3.6 1.6 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KEZ35267.1 - 2e-13 50.8 2.5 2e-13 50.8 2.5 2.2 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain Iron_transport PF10634.9 KEZ35268.1 - 0.003 17.8 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Fe2+ transport protein MG2 PF01835.19 KEZ35268.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 2 0 0 2 2 2 0 MG2 domain Ost5 PF05251.12 KEZ35269.1 - 1.9 8.8 6.8 0.85 9.9 3.1 2.2 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Hemerythrin PF01814.23 KEZ35270.1 - 3.8e-11 43.7 0.3 4.9e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain 2OG-FeII_Oxy_3 PF13640.6 KEZ35271.1 - 0.11 13.3 0.0 0.21 12.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.6 KEZ35272.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ35272.1 - 0.024 15.3 0.0 3 8.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Carn_acyltransf PF00755.20 KEZ35273.1 - 4.4e-153 511.0 0.0 5.1e-153 510.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Polysacc_synt PF01943.17 KEZ35274.1 - 2.7 7.3 16.6 0.57 9.5 12.8 1.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_hydro_26 PF02156.15 KEZ35276.1 - 1.6e-09 37.6 2.2 2.5e-09 37.0 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Cellulase PF00150.18 KEZ35276.1 - 0.0072 15.8 0.6 0.011 15.2 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 2-oxogl_dehyd_N PF16078.5 KEZ35276.1 - 4.5 6.9 6.4 0.97 9.1 1.6 2.4 2 1 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus GSHPx PF00255.19 KEZ35277.1 - 3.5e-39 132.7 0.0 4.5e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KEZ35277.1 - 2.8e-05 24.1 0.0 0.00075 19.4 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KEZ35277.1 - 0.012 15.3 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Redoxin Trm112p PF03966.16 KEZ35278.1 - 1.9e-07 31.6 0.1 6.1e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Trm112p-like protein S1 PF00575.23 KEZ35279.1 - 8.4e-78 256.7 29.3 3.6e-25 88.1 1.7 4.2 4 0 0 4 4 4 4 S1 RNA binding domain S1_2 PF13509.6 KEZ35279.1 - 9.4e-06 25.6 4.3 0.094 12.8 0.1 4.8 4 2 0 4 4 4 2 S1 domain DUF2110 PF09883.9 KEZ35279.1 - 4.8e-05 23.1 2.8 0.72 9.4 0.1 3.3 2 1 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2110) RNase_II_C_S1 PF18614.1 KEZ35279.1 - 0.00057 19.8 3.3 0.19 11.7 0.5 3.8 3 0 0 3 3 3 2 RNase II-type exonuclease C-terminal S1 domain DUF2187 PF09953.9 KEZ35279.1 - 0.028 14.4 0.5 0.76 9.8 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) RsgI_N PF12791.7 KEZ35279.1 - 0.12 12.3 0.1 10 6.1 0.0 2.8 2 0 0 2 2 2 0 Anti-sigma factor N-terminus MRP-S35 PF10246.9 KEZ35279.1 - 0.47 10.4 1.9 50 3.9 0.1 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal protein MRP-S35 YcgR PF07317.12 KEZ35279.1 - 0.67 9.9 4.8 7.7 6.5 0.0 3.9 5 0 0 5 5 5 0 Flagellar regulator YcgR CsrA PF02599.16 KEZ35279.1 - 2.5 8.1 6.9 15 5.6 0.6 3.6 4 0 0 4 4 4 0 Global regulator protein family Acyl_transf_3 PF01757.22 KEZ35280.1 - 8.1e-25 87.6 33.9 1.1e-24 87.2 33.9 1.2 1 0 0 1 1 1 1 Acyltransferase family FtsX PF02687.21 KEZ35280.1 - 0.98 9.9 5.0 0.74 10.3 1.8 2.5 2 0 0 2 2 2 0 FtsX-like permease family PMT_2 PF13231.6 KEZ35281.1 - 1.5e-13 51.3 15.7 1.5e-13 51.3 15.7 2.6 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Acyl_transf_3 PF01757.22 KEZ35282.1 - 4e-21 75.5 24.6 5.9e-21 74.9 24.6 1.2 1 0 0 1 1 1 1 Acyltransferase family Lipase_GDSL_2 PF13472.6 KEZ35282.1 - 1.5e-07 32.0 0.4 2.8e-07 31.1 0.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ35282.1 - 0.044 13.8 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase GDP_Man_Dehyd PF16363.5 KEZ35283.1 - 1.2e-25 90.6 0.0 1.3e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ35283.1 - 4.8e-16 59.0 0.0 5.1e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ35283.1 - 5.6e-05 22.8 0.0 6.2e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KEZ35283.1 - 0.0065 15.6 0.0 0.0077 15.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEZ35283.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H-binding LZ_Tnp_IS66 PF13007.7 KEZ35284.1 - 7.4e-05 23.5 0.6 7.4e-05 23.5 0.6 2.2 2 1 0 2 2 2 1 Transposase C of IS166 homeodomain MscS_porin PF12795.7 KEZ35284.1 - 0.0028 17.2 0.7 0.003 17.1 0.7 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain bZIP_2 PF07716.15 KEZ35284.1 - 0.069 13.2 5.4 2.2 8.4 3.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper TPD52 PF04201.15 KEZ35284.1 - 0.15 11.7 0.8 0.18 11.4 0.7 1.3 1 1 0 1 1 1 0 Tumour protein D52 family HALZ PF02183.18 KEZ35284.1 - 0.23 11.7 1.8 8.4 6.7 0.8 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper DEAD PF00270.29 KEZ35285.1 - 6.3e-13 48.9 0.0 8.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEZ35285.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ODAPH PF15848.5 KEZ35286.1 - 0.03 14.8 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 Odontogenesis associated phosphoprotein PFK PF00365.20 KEZ35287.1 - 1.4e-64 218.2 0.0 1.6e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 KEZ35287.1 - 0.052 13.2 0.1 0.21 11.2 0.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF3948 PF13134.6 KEZ35288.1 - 0.11 12.2 1.3 0.21 11.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) MTES_1575 PF18741.1 KEZ35289.1 - 1.4e-26 92.5 0.2 1.9e-25 88.9 0.0 2.6 2 1 0 2 2 1 1 REase_MTES_1575 AAA_11 PF13086.6 KEZ35289.1 - 1.5e-12 47.9 0.4 1.4e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KEZ35289.1 - 1.8e-11 44.1 0.0 4.2e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ35289.1 - 3.5e-10 39.9 5.1 5.9e-07 29.4 1.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEZ35289.1 - 2.7e-08 34.3 1.0 0.0002 21.7 0.2 2.8 3 0 0 3 3 2 2 AAA domain DUF559 PF04480.12 KEZ35289.1 - 1.7e-05 24.6 0.0 0.0032 17.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF559) Helicase_RecD PF05127.14 KEZ35289.1 - 2.9e-05 24.0 0.3 0.0003 20.7 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 KEZ35289.1 - 0.00017 22.0 1.1 0.00017 22.0 1.1 4.2 3 1 1 4 4 4 1 AAA ATPase domain MeaB PF03308.16 KEZ35289.1 - 0.00018 20.6 0.1 0.00054 19.0 0.1 1.8 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KEZ35289.1 - 0.0007 19.4 0.1 5.2 6.7 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KEZ35289.1 - 0.011 16.0 0.0 0.056 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEZ35289.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 KEZ35289.1 - 0.044 13.9 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.21 KEZ35289.1 - 0.059 12.9 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Fer4_NifH PF00142.18 KEZ35289.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FtsK_SpoIIIE PF01580.18 KEZ35289.1 - 0.11 11.8 0.1 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1318 PF07027.12 KEZ35290.1 - 0.092 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) ABM PF03992.16 KEZ35291.1 - 6.1e-09 35.9 0.0 7.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KEZ35292.1 - 2.8e-10 40.2 0.7 4e-10 39.7 0.7 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase adh_short_C2 PF13561.6 KEZ35293.1 - 3.2e-64 216.7 0.5 3.8e-64 216.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ35293.1 - 8.5e-48 162.4 0.1 1e-47 162.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ35293.1 - 2.1e-14 53.8 0.3 3e-14 53.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ35293.1 - 6.6e-05 22.5 0.6 0.00013 21.6 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ35293.1 - 0.003 16.9 0.1 0.11 11.8 0.0 2.3 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 KEZ35293.1 - 0.0081 16.1 1.1 0.0081 16.1 1.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEZ35293.1 - 0.03 13.7 0.2 0.041 13.3 0.2 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_16 PF10294.9 KEZ35293.1 - 0.056 13.2 0.3 0.09 12.5 0.3 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Sacchrp_dh_NADP PF03435.18 KEZ35293.1 - 0.057 13.7 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KEZ35293.1 - 0.094 12.1 0.1 5.2 6.4 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 KEZ35294.1 - 1.4e-32 113.3 2.9 3.2e-31 108.8 0.8 2.2 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ35294.1 - 8.2e-24 83.9 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KEZ35295.1 - 1.9e-51 175.1 2.6 3.3e-51 174.3 2.6 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ35295.1 - 3.2e-33 114.2 0.1 5.8e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KEZ35295.1 - 0.0021 17.4 0.5 0.005 16.2 0.0 1.8 3 0 0 3 3 3 1 Thiolase, N-terminal domain Cupin_2 PF07883.11 KEZ35296.1 - 1e-14 53.9 0.3 1.5e-14 53.4 0.3 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEZ35296.1 - 8.9e-05 22.4 0.2 0.00012 22.0 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KEZ35296.1 - 0.00079 19.3 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Polyketide_cyc PF03364.20 KEZ35297.1 - 5.8e-15 55.7 0.9 6.9e-15 55.4 0.9 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KEZ35297.1 - 4e-13 49.8 1.9 4.8e-13 49.6 1.9 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KEZ35297.1 - 0.0003 21.0 2.3 0.00035 20.8 2.3 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein PP-binding PF00550.25 KEZ35298.1 - 7.6e-09 35.8 0.8 1.7e-08 34.7 0.3 1.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Cyclase_polyket PF04673.12 KEZ35299.1 - 1.3e-41 141.1 0.0 1.5e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide synthesis cyclase HTH_23 PF13384.6 KEZ35301.1 - 1.5e-07 31.0 0.3 6.1e-05 22.7 0.1 2.9 2 0 0 2 2 2 1 Homeodomain-like domain GerE PF00196.19 KEZ35301.1 - 6.8e-07 28.7 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_17 PF12728.7 KEZ35301.1 - 5.7e-06 26.4 0.1 0.028 14.6 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.6 KEZ35301.1 - 0.00012 22.1 3.1 0.066 13.2 0.3 2.9 3 0 0 3 3 3 2 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 KEZ35301.1 - 0.00032 20.1 0.2 0.011 15.1 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 KEZ35301.1 - 0.0019 17.8 0.1 0.1 12.3 0.1 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 TrmB PF01978.19 KEZ35301.1 - 0.0048 16.8 0.1 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF746 PF05344.11 KEZ35301.1 - 0.0056 16.5 0.5 0.049 13.5 0.2 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF746) HTH_11 PF08279.12 KEZ35301.1 - 0.0064 16.4 0.1 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 HTH domain HTH_28 PF13518.6 KEZ35301.1 - 0.0073 16.4 0.6 0.089 12.9 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ35301.1 - 0.023 14.2 0.9 1.2 8.8 0.2 3.1 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_3 PF01381.22 KEZ35301.1 - 0.09 12.8 0.1 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix SLT_L PF14718.6 KEZ35301.1 - 0.14 12.4 2.6 1.7 8.8 0.0 3.1 2 1 1 3 3 3 0 Soluble lytic murein transglycosylase L domain MerR PF00376.23 KEZ35301.1 - 0.66 9.8 3.0 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 MerR family regulatory protein ATP_bind_1 PF03029.17 KEZ35302.1 - 8.6e-30 104.3 0.6 4.4e-28 98.7 0.6 2.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KEZ35302.1 - 0.0056 16.6 0.0 0.56 10.1 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KEZ35302.1 - 0.0098 15.5 0.0 0.037 13.6 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEZ35302.1 - 0.057 13.6 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KEZ35302.1 - 0.081 12.6 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ35302.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ35302.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.15 KEZ35302.1 - 0.2 11.6 0.7 0.4 10.6 0.7 1.5 1 0 0 1 1 1 0 NTPase DUF742 PF05331.11 KEZ35303.1 - 5e-34 116.5 2.5 5.7e-34 116.4 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) MarR_2 PF12802.7 KEZ35303.1 - 0.026 14.4 0.3 0.04 13.8 0.3 1.4 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 KEZ35303.1 - 0.047 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Robl_LC7 PF03259.17 KEZ35304.1 - 4.5e-25 87.2 0.1 7e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain NIT PF08376.10 KEZ35305.1 - 3.1e-39 135.8 26.7 3.1e-39 135.8 26.7 1.9 2 0 0 2 2 2 1 Nitrate and nitrite sensing HATPase_c PF02518.26 KEZ35305.1 - 2.7e-08 34.3 0.0 6.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KEZ35305.1 - 1.2e-06 28.8 1.9 2.4e-06 27.8 0.3 2.5 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 KEZ35305.1 - 2.5e-05 24.1 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 4HB_MCP_1 PF12729.7 KEZ35305.1 - 0.09 12.3 5.9 3.9 7.0 0.1 4.1 2 1 2 4 4 4 0 Four helix bundle sensory module for signal transduction 3-alpha PF03475.14 KEZ35305.1 - 0.096 12.6 0.2 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 3-alpha domain ECH_1 PF00378.20 KEZ35306.1 - 1.3e-44 152.5 0.0 1.5e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ35306.1 - 9.4e-27 94.4 0.0 1.1e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF445 PF04286.12 KEZ35308.1 - 5.2e-102 342.4 0.0 6e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) SRP54 PF00448.22 KEZ35308.1 - 0.044 13.4 0.2 3.9 7.1 0.3 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain PEP-utilisers_N PF05524.13 KEZ35308.1 - 0.33 11.1 1.8 22 5.2 0.0 2.8 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal TraT PF05818.12 KEZ35308.1 - 0.81 9.3 0.0 0.81 9.3 0.0 1.9 3 0 0 3 3 3 0 Enterobacterial TraT complement resistance protein DUF2267 PF10025.9 KEZ35308.1 - 1.1 9.5 8.4 13 6.0 4.2 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) GT87 PF09594.10 KEZ35309.1 - 2.3e-11 43.9 35.9 2.3e-11 43.9 35.9 2.5 2 0 0 2 2 2 1 Glycosyltransferase family 87 DEAD PF00270.29 KEZ35310.1 - 1.4e-24 86.8 0.0 4.5e-24 85.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ35310.1 - 6.1e-23 81.3 0.0 1.6e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hydrolase_4 PF12146.8 KEZ35312.1 - 0.0009 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ35312.1 - 0.014 15.0 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pyridoxal_deC PF00282.19 KEZ35313.1 - 4.4e-41 140.8 0.0 6.3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KEZ35313.1 - 3.2e-07 29.9 0.1 4.3e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KEZ35313.1 - 4.8e-05 22.5 0.0 8.9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KEZ35313.1 - 0.04 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PHP PF02811.19 KEZ35314.1 - 5.8e-14 52.7 0.0 6.2e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 PHP domain CMAS PF02353.20 KEZ35316.1 - 1.8e-87 293.1 0.0 2.2e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KEZ35316.1 - 7.1e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ35316.1 - 1.5e-14 54.4 0.0 2.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35316.1 - 6.7e-12 45.5 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35316.1 - 2.8e-11 44.0 0.0 4.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ35316.1 - 2.5e-06 27.4 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEZ35316.1 - 0.00016 21.6 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PCMT PF01135.19 KEZ35316.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KEZ35316.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KEZ35316.1 - 0.0034 17.0 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KEZ35316.1 - 0.0056 16.6 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KEZ35316.1 - 0.022 15.8 0.1 0.073 14.1 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KEZ35316.1 - 0.048 12.6 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.11 KEZ35316.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 KEZ35316.1 - 0.19 11.0 0.0 0.45 9.8 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 KEZ35317.1 - 3.5e-35 121.6 60.8 1.3e-34 119.7 58.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ35317.1 - 4.6 6.0 24.4 0.12 11.2 9.4 3.6 2 1 1 3 3 3 0 Sugar (and other) transporter Aldedh PF00171.22 KEZ35318.1 - 2.5e-127 425.2 0.2 2.1e-90 303.5 0.3 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Aminotran_3 PF00202.21 KEZ35319.1 - 2.7e-72 243.7 0.0 3.4e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.25 KEZ35320.1 - 3e-37 128.4 0.0 3.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Lipoprotein_21 PF14041.6 KEZ35320.1 - 3.8e-22 78.2 0.2 3.8e-22 78.2 0.2 1.8 2 0 0 2 2 2 1 LppP/LprE lipoprotein Pkinase_Tyr PF07714.17 KEZ35320.1 - 1.3e-19 70.5 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ35320.1 - 2.4e-07 30.9 14.2 0.00023 21.2 0.1 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ35320.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Plasmodium_HRP PF05403.11 KEZ35320.1 - 0.0028 17.5 20.0 0.0056 16.5 20.0 1.4 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) Pkinase_fungal PF17667.1 KEZ35320.1 - 0.025 13.3 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KEZ35320.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ORF_12_N PF18042.1 KEZ35320.1 - 0.083 13.3 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 ORF 12 gene product N-terminal Pkinase PF00069.25 KEZ35321.1 - 2e-40 138.8 0.0 2.5e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ35321.1 - 4.1e-23 82.0 0.0 4.9e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ35321.1 - 1.4e-05 25.2 9.5 0.0014 18.6 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ35321.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ35321.1 - 0.029 13.2 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KEZ35321.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 RIO1 family DUF3040 PF11239.8 KEZ35321.1 - 6.2 7.2 5.6 15 5.9 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Sod_Cu PF00080.20 KEZ35322.1 - 8.7e-09 35.7 0.4 1.2e-08 35.2 0.4 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PIN PF01850.21 KEZ35323.1 - 5e-15 56.1 0.0 5.6e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 PIN domain PhdYeFM_antitox PF02604.19 KEZ35324.1 - 2.3e-09 36.9 0.0 6.2e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Raf1_HTH PF18579.1 KEZ35324.1 - 0.055 13.2 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Nitroreductase PF00881.24 KEZ35325.1 - 2.9e-23 82.8 0.0 6.7e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KEZ35325.1 - 0.076 12.6 0.0 5.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase Transposase_31 PF04754.12 KEZ35327.1 - 1.1e-58 198.3 0.0 1.3e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Putative transposase, YhgA-like DUF4351 PF14261.6 KEZ35327.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Gp49 PF05973.14 KEZ35328.1 - 1.7e-21 76.1 0.0 2e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) HTH_31 PF13560.6 KEZ35329.1 - 2.1e-12 47.2 0.6 4.4e-12 46.2 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ35329.1 - 2.5e-11 43.4 0.1 3.6e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 KEZ35329.1 - 2.4e-10 40.2 0.2 2.9e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ35329.1 - 4.4e-08 33.0 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ35329.1 - 1.4e-07 30.9 0.5 2.8e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_25 PF13413.6 KEZ35329.1 - 0.00032 20.5 0.1 0.00064 19.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ35329.1 - 0.00072 19.3 0.2 0.0017 18.1 0.1 1.7 2 0 0 2 2 2 1 Homeodomain-like domain MqsA_antitoxin PF15731.5 KEZ35329.1 - 0.00097 19.3 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA MarR_2 PF12802.7 KEZ35329.1 - 0.0014 18.5 0.2 0.0031 17.4 0.2 1.8 1 1 0 1 1 1 1 MarR family HTH_28 PF13518.6 KEZ35329.1 - 0.0025 17.9 0.1 0.23 11.6 0.0 2.5 1 1 1 2 2 2 2 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ35329.1 - 0.0055 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 KEZ35329.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KEZ35329.1 - 0.011 15.6 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 ECF sigma factor KORA PF16509.5 KEZ35329.1 - 0.017 15.4 0.1 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_Crp_2 PF13545.6 KEZ35329.1 - 0.018 15.0 0.2 0.028 14.4 0.2 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Pou PF00157.17 KEZ35329.1 - 0.031 14.2 0.1 0.057 13.4 0.1 1.4 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_24 PF13412.6 KEZ35329.1 - 0.043 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 KEZ35329.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Phage_CI_repr PF07022.13 KEZ35329.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Prok-E2_B PF14461.6 KEZ35329.1 - 0.17 11.6 0.1 3.8 7.2 0.0 2.0 1 1 1 2 2 2 0 Prokaryotic E2 family B GntR PF00392.21 KEZ35330.1 - 4.2e-18 64.7 0.9 7.3e-18 64.0 0.9 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 KEZ35330.1 - 1.5e-15 57.7 6.7 3.2e-15 56.7 6.7 1.5 1 0 0 1 1 1 1 FCD domain Rrf2 PF02082.20 KEZ35330.1 - 0.00028 21.2 0.0 0.00095 19.5 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.12 KEZ35330.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 KEZ35330.1 - 0.044 13.9 0.3 0.044 13.9 0.3 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain tRNA-synt_1c PF00749.21 KEZ35331.1 - 2.9e-75 253.1 0.0 4.8e-75 252.4 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HTH_20 PF12840.7 KEZ35332.1 - 3.7e-08 33.3 0.5 6.8e-08 32.5 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HxlR PF01638.17 KEZ35332.1 - 6.2e-08 32.4 0.0 9.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 KEZ35332.1 - 8.8e-05 22.3 0.5 0.00015 21.6 0.5 1.5 1 0 0 1 1 1 1 MarR family HemN_C PF06969.16 KEZ35332.1 - 0.0019 18.2 0.1 0.0038 17.3 0.1 1.5 1 0 0 1 1 1 1 HemN C-terminal domain HTH_27 PF13463.6 KEZ35332.1 - 0.0039 17.7 0.9 0.005 17.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_5 PF01022.20 KEZ35332.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 KEZ35332.1 - 0.036 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 KEZ35332.1 - 0.06 13.5 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF4423 PF14394.6 KEZ35332.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF505 PF04458.12 KEZ35332.1 - 0.094 11.1 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) HTH_24 PF13412.6 KEZ35332.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Mrr_N PF14338.6 KEZ35332.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain HTH_45 PF14947.6 KEZ35332.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix Sporozoite_P67 PF05642.11 KEZ35333.1 - 0.37 8.8 4.1 0.38 8.8 4.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DEDD_Tnp_IS110 PF01548.17 KEZ35334.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-UBP_var PF17807.1 KEZ35334.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Variant UBP zinc finger DEDD_Tnp_IS110 PF01548.17 KEZ35335.1 - 1.6e-15 57.3 0.0 2.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 KEZ35335.1 - 4.2e-14 52.6 0.0 7.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HrpB7 PF09486.10 KEZ35335.1 - 0.039 14.3 0.1 9.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) MerR_2 PF13591.6 KEZ35335.1 - 0.077 12.9 0.1 0.33 10.9 0.0 2.1 2 1 1 3 3 3 0 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 KEZ35335.1 - 0.41 11.2 3.3 0.79 10.3 0.2 2.7 3 0 0 3 3 3 0 MerR, DNA binding 2_5_RNA_ligase2 PF13563.6 KEZ35337.1 - 5.2e-09 36.2 0.1 6.5e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KEZ35337.1 - 2.6e-07 30.7 0.2 3.7e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase TPR_12 PF13424.6 KEZ35338.1 - 3.3e-07 30.5 5.1 7.6e-05 22.9 0.8 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat HTH_31 PF13560.6 KEZ35338.1 - 0.00052 20.3 3.9 0.0023 18.3 0.0 3.9 4 0 0 4 4 4 1 Helix-turn-helix domain TPR_2 PF07719.17 KEZ35338.1 - 0.14 12.3 8.0 22 5.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ35338.1 - 0.2 11.9 1.7 31 5.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ35338.1 - 0.94 10.5 8.6 1.3 10.0 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ35338.1 - 2.1 8.3 8.4 9.3 6.3 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 KEZ35340.1 - 7e-07 29.0 1.0 1.4e-06 28.0 1.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_4 PF07993.12 KEZ35341.1 - 2.4e-41 141.6 0.1 1.6e-35 122.5 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KEZ35341.1 - 8.5e-13 48.0 0.2 2.1e-12 46.8 0.2 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KEZ35341.1 - 6e-11 42.3 0.0 8.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEZ35341.1 - 2.7e-08 33.9 0.5 5.8e-08 32.8 0.5 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ35341.1 - 0.00015 20.9 0.1 0.0019 17.3 0.1 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEZ35341.1 - 0.0012 19.3 0.2 0.0052 17.2 0.0 2.1 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain DUF2156 PF09924.9 KEZ35342.1 - 3.3e-57 193.8 0.0 3.8e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_6 PF13480.7 KEZ35342.1 - 0.0063 16.7 1.4 0.02 15.1 0.4 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CPBP PF02517.16 KEZ35343.1 - 2.7e-11 43.7 4.1 2.7e-11 43.7 4.1 1.9 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DDDD PF10161.9 KEZ35343.1 - 0.59 9.9 3.6 0.23 11.2 0.4 2.0 2 0 0 2 2 2 0 Putative mitochondrial precursor protein MFS_1 PF07690.16 KEZ35344.1 - 7.7e-48 163.2 73.4 1.1e-41 143.0 38.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ35344.1 - 0.00035 19.6 20.2 0.0019 17.2 0.2 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ35344.1 - 0.00057 18.4 0.4 0.00057 18.4 0.4 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEZ35344.1 - 0.00062 18.2 1.8 0.013 13.9 0.1 3.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KEZ35344.1 - 0.00065 18.4 18.1 0.16 10.4 5.6 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein UNC-93 PF05978.16 KEZ35344.1 - 0.032 13.9 0.7 0.058 13.1 0.1 1.7 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Erythro_esteras PF05139.14 KEZ35344.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.5 1 1 0 2 2 2 0 Erythromycin esterase MFS_4 PF06779.14 KEZ35344.1 - 1.7 7.8 35.0 6.7 5.9 34.7 2.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Methyltransf_11 PF08241.12 KEZ35345.1 - 2e-14 54.0 0.0 9.1e-14 51.9 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ35345.1 - 2.5e-14 53.8 0.0 5.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ35345.1 - 1.8e-12 47.3 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ35345.1 - 1.8e-12 47.1 0.0 2.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEZ35345.1 - 9.8e-09 35.9 0.0 1.9e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35345.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ35345.1 - 1.2e-05 25.0 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N_2 PF13602.6 KEZ35345.1 - 0.00028 21.9 0.1 0.0016 19.5 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase PCMT PF01135.19 KEZ35345.1 - 0.00071 19.4 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KEZ35345.1 - 0.0023 17.0 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 KEZ35345.1 - 0.0046 16.6 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 KEZ35345.1 - 0.0078 16.1 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase TetR_C_20 PF17925.1 KEZ35345.1 - 0.045 14.0 0.7 0.14 12.5 0.2 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_2 PF00891.18 KEZ35345.1 - 0.063 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KEZ35345.1 - 0.19 11.7 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MMPL PF03176.15 KEZ35346.1 - 1.1e-85 287.6 30.8 1.4e-44 152.5 13.4 2.3 2 0 0 2 2 2 2 MMPL family Patched PF02460.18 KEZ35346.1 - 0.0058 14.8 4.8 0.0066 14.6 2.4 2.2 2 0 0 2 2 2 1 Patched family Abhydrolase_1 PF00561.20 KEZ35347.1 - 2.8e-24 86.1 1.0 7.8e-23 81.4 1.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ35347.1 - 2.6e-22 80.5 0.1 3.2e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ35347.1 - 2e-11 43.6 0.0 3.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEZ35347.1 - 5.6e-05 22.0 0.0 8.5e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KEZ35347.1 - 0.0051 16.9 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Mn_catalase PF05067.12 KEZ35347.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Manganese containing catalase Creatinase_N PF01321.18 KEZ35347.1 - 0.17 12.5 0.0 0.38 11.4 0.0 1.5 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain NUDIX PF00293.28 KEZ35349.1 - 1.6e-20 73.5 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEZ35349.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain DUF2892 PF11127.8 KEZ35350.1 - 0.73 9.9 3.6 0.59 10.2 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) HTH_5 PF01022.20 KEZ35351.1 - 4.2e-15 55.3 0.1 6.1e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KEZ35351.1 - 1.3e-12 47.6 0.8 2.5e-12 46.7 0.2 1.7 1 1 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ35351.1 - 8.3e-07 28.8 0.1 1.7e-06 27.8 0.1 1.4 1 1 0 1 1 1 1 MarR family MarR PF01047.22 KEZ35351.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KEZ35351.1 - 0.0027 17.3 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 KEZ35351.1 - 0.0028 17.8 0.0 0.0086 16.3 0.0 1.8 2 0 0 2 2 2 1 PaaX-like protein TrmB PF01978.19 KEZ35351.1 - 0.0044 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 KEZ35351.1 - 0.0052 16.9 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KEZ35351.1 - 0.0076 16.0 0.4 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ35351.1 - 0.0085 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain RP-C PF03428.13 KEZ35351.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF4423 PF14394.6 KEZ35351.1 - 0.097 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Penicillinase_R PF03965.16 KEZ35351.1 - 0.21 11.9 0.0 0.59 10.5 0.0 1.6 2 0 0 2 2 2 0 Penicillinase repressor CbtB PF09489.10 KEZ35352.1 - 7.5e-11 42.0 0.6 9e-11 41.7 0.6 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) CbtA PF09490.10 KEZ35353.1 - 1.9e-71 240.7 22.2 2.3e-71 240.4 22.2 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) TrbC PF04956.13 KEZ35353.1 - 0.24 11.7 0.2 0.24 11.7 0.2 3.9 3 1 1 4 4 4 0 TrbC/VIRB2 family Otopetrin PF03189.13 KEZ35353.1 - 0.24 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Otopetrin DUF4134 PF13572.6 KEZ35353.1 - 1.7 9.0 7.7 0.42 10.9 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) His_Phos_1 PF00300.22 KEZ35354.1 - 1e-21 77.5 0.1 2.2e-21 76.4 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DnaJ_CXXCXGXG PF00684.19 KEZ35355.1 - 9.7e-05 22.7 6.5 0.00015 22.1 6.5 1.4 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ35355.1 - 0.00037 20.4 5.2 0.00058 19.8 5.2 1.3 1 1 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein Elf1 PF05129.13 KEZ35355.1 - 0.0028 17.7 0.7 0.0029 17.6 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 KEZ35355.1 - 0.0068 16.8 1.7 0.0073 16.7 1.7 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.12 KEZ35355.1 - 0.023 15.0 4.2 0.047 14.0 4.2 1.5 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF5351 PF17302.2 KEZ35355.1 - 0.12 12.6 7.6 1.7 8.9 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5351) DUF1356 PF07092.12 KEZ35355.1 - 0.2 10.9 5.7 0.092 12.0 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Zn-ribbon_8 PF09723.10 KEZ35355.1 - 0.89 9.7 4.7 1.7 8.8 0.7 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KEZ35355.1 - 0.93 9.8 4.4 2.9 8.2 0.8 2.0 1 1 1 2 2 2 0 zinc-ribbon U71 PF17474.2 KEZ35355.1 - 2.4 8.2 9.0 5 7.1 1.5 2.2 1 1 1 2 2 2 0 Tegument protein UL11 homolog PCMT PF01135.19 KEZ35356.1 - 1.5e-30 106.5 0.0 2.7e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KEZ35356.1 - 7e-08 31.9 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KEZ35356.1 - 2.2e-07 31.5 0.0 3.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35356.1 - 3.9e-05 23.5 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35356.1 - 0.00024 21.8 0.0 0.00045 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEZ35356.1 - 0.00029 20.1 0.0 0.00042 19.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 KEZ35356.1 - 0.00034 20.4 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ35356.1 - 0.00078 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KEZ35356.1 - 0.0033 18.0 0.0 0.0058 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KEZ35356.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ACP_syn_III_C PF08541.10 KEZ35356.1 - 0.074 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CMAS PF02353.20 KEZ35356.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KEZ35356.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Sulfate_transp PF00916.20 KEZ35357.1 - 1.5e-64 218.2 16.6 2e-64 217.7 16.6 1.2 1 0 0 1 1 1 1 Sulfate permease family Pro_CA PF00484.19 KEZ35357.1 - 3.1e-45 154.3 0.0 4.7e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase MFS_MOT1 PF16983.5 KEZ35357.1 - 1.2e-05 25.6 5.4 1.2e-05 25.6 5.4 3.4 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily TcdA_TcdB_pore PF12920.7 KEZ35357.1 - 9.2 4.4 5.5 17 3.5 5.5 1.3 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain NAD_binding_8 PF13450.6 KEZ35358.1 - 9.9e-09 35.3 0.1 9.9e-09 35.3 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEZ35358.1 - 2.4e-07 30.4 1.5 0.00095 18.6 0.2 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KEZ35358.1 - 3.5e-06 26.4 0.1 5.9e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KEZ35358.1 - 5.4e-05 22.9 7.1 0.00075 19.2 0.9 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ35358.1 - 9.7e-05 21.6 3.0 0.00016 20.9 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEZ35358.1 - 0.0002 20.2 0.0 0.0005 18.9 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KEZ35358.1 - 0.00037 19.9 0.5 0.00037 19.9 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KEZ35358.1 - 0.00056 19.4 1.6 0.0012 18.3 1.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ35358.1 - 0.00091 18.5 0.1 0.0015 17.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ35358.1 - 0.018 14.3 0.3 0.027 13.7 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ35358.1 - 0.063 12.3 0.6 0.095 11.8 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KEZ35358.1 - 0.16 12.5 0.0 2.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2278 PF10042.9 KEZ35360.1 - 2.7e-70 236.5 0.0 3.3e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 KEZ35360.1 - 4.7e-09 36.6 0.0 7.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Lamin Tail Domain POR PF01558.18 KEZ35361.1 - 1.3e-29 103.5 0.0 1.6e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase SpoIIE PF07228.12 KEZ35362.1 - 2.1e-32 112.6 0.3 2.8e-32 112.2 0.3 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) P_C PF06640.11 KEZ35362.1 - 0.028 14.6 0.3 0.045 13.9 0.2 1.5 1 1 0 1 1 1 0 P protein C-terminus Nitro_FeMo-Co PF02579.17 KEZ35364.1 - 0.094 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor GAF_2 PF13185.6 KEZ35365.1 - 9.7e-29 100.4 14.8 4e-18 66.0 0.3 3.1 4 0 0 4 4 4 2 GAF domain GAF PF01590.26 KEZ35365.1 - 3.1e-21 76.4 1.1 2.9e-10 40.9 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KEZ35365.1 - 4.1e-21 75.7 4.1 8.2e-12 45.6 0.2 4.0 3 1 0 3 3 3 2 GAF domain HisKA_3 PF07730.13 KEZ35365.1 - 7e-09 36.1 0.5 7e-09 36.1 0.5 3.9 4 0 0 4 4 4 1 Histidine kinase HATPase_c_2 PF13581.6 KEZ35365.1 - 0.00026 20.9 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ35365.1 - 0.00038 20.9 0.4 0.0064 17.0 0.6 2.7 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SpoVT_C PF15714.5 KEZ35365.1 - 0.063 13.3 0.0 10 6.2 0.0 3.0 3 1 1 4 4 4 0 Stage V sporulation protein T C-terminal, transcription factor ArAE_2_N PF10337.9 KEZ35365.1 - 0.11 11.6 0.2 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal PspA_IM30 PF04012.12 KEZ35365.1 - 0.27 10.8 2.5 12 5.4 0.0 2.4 2 0 0 2 2 2 0 PspA/IM30 family AAA_33 PF13671.6 KEZ35366.1 - 5.6e-13 49.3 0.5 5.6e-13 49.3 0.5 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ35366.1 - 0.0036 17.8 0.0 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ35366.1 - 0.011 16.2 6.6 0.022 15.1 4.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KEZ35366.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KEZ35366.1 - 0.16 11.9 1.0 2.5 8.0 0.9 2.3 2 0 0 2 2 2 0 NACHT domain Response_reg PF00072.24 KEZ35367.1 - 1e-22 80.4 0.1 2.1e-22 79.4 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 KEZ35367.1 - 1e-20 73.0 0.6 1.7e-20 72.3 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ35367.1 - 6.9e-08 32.1 0.3 1.3e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ35367.1 - 1.5e-05 24.4 0.5 5.1e-05 22.7 0.5 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KEZ35367.1 - 0.00054 19.7 0.1 0.0017 18.1 0.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KEZ35367.1 - 0.0015 18.0 1.3 0.0036 16.8 0.2 2.2 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KEZ35367.1 - 0.0045 16.7 0.4 0.009 15.7 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3071 PF11268.8 KEZ35367.1 - 0.076 13.1 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) HTH_11 PF08279.12 KEZ35367.1 - 0.092 12.7 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 HTH domain HTH_Tnp_4 PF13613.6 KEZ35367.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease TetR_N PF00440.23 KEZ35368.1 - 5.3e-05 22.9 0.0 0.00019 21.1 0.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 KEZ35368.1 - 0.0037 17.3 3.9 0.0057 16.7 2.1 2.3 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 KEZ35368.1 - 0.0042 17.3 1.1 0.0086 16.3 0.6 1.9 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_9 PF14514.6 KEZ35368.1 - 0.028 14.5 0.2 0.053 13.6 0.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_IclR PF09339.10 KEZ35368.1 - 0.045 13.6 2.3 6.3 6.7 0.0 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_17 PF12728.7 KEZ35368.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_C_6 PF13977.6 KEZ35368.1 - 1.1 9.6 15.5 0.32 11.2 5.6 2.5 1 1 1 2 2 2 0 BetI-type transcriptional repressor, C-terminal PSK_trans_fac PF07704.11 KEZ35368.1 - 4 8.3 7.6 11 6.9 3.7 2.7 1 1 1 2 2 2 0 Rv0623-like transcription factor CoA_transf_3 PF02515.17 KEZ35369.1 - 7.4e-84 282.0 0.1 9.2e-84 281.7 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III WD40 PF00400.32 KEZ35370.1 - 8.1e-47 156.2 6.6 4.7e-10 39.9 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.25 KEZ35370.1 - 2.9e-37 128.5 0.0 4.1e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ35370.1 - 4.8e-24 85.0 0.0 7e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KEZ35370.1 - 2.5e-15 56.5 0.0 0.12 12.7 0.0 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ35370.1 - 2.1e-11 43.4 0.0 0.07 12.1 0.0 5.5 1 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein APH PF01636.23 KEZ35370.1 - 1.9e-08 34.6 2.5 0.0064 16.4 2.4 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ35370.1 - 0.00033 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PD40 PF07676.12 KEZ35370.1 - 0.0013 18.6 1.2 6.9 6.7 0.0 5.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KEZ35370.1 - 0.0032 17.1 1.2 21 4.9 0.0 5.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Pkinase_fungal PF17667.1 KEZ35370.1 - 0.0059 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEZ35370.1 - 0.0085 15.7 0.0 0.056 13.0 0.0 2.0 1 1 1 2 2 2 1 RIO1 family DUF5570 PF17731.1 KEZ35370.1 - 0.0092 16.1 3.6 23 5.1 0.0 5.0 2 1 4 6 6 6 0 Family of unknown function (DUF5570) REV PF00424.18 KEZ35370.1 - 0.025 14.6 0.1 0.079 13.0 0.1 1.8 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ret2_MD PF18528.1 KEZ35370.1 - 0.06 13.7 0.0 3.5 8.1 0.0 3.2 2 1 1 3 3 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Acid_PPase PF12689.7 KEZ35370.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Nucleoporin_N PF08801.11 KEZ35370.1 - 0.22 10.2 0.0 13 4.4 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like Glyco_tranf_2_3 PF13641.6 KEZ35371.1 - 3.4e-20 72.9 0.0 5.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ35371.1 - 4.5e-20 71.8 0.0 8.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KEZ35371.1 - 1.4e-19 70.8 10.7 2.9e-17 63.2 5.8 2.6 2 1 0 2 2 2 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEZ35371.1 - 2.2e-18 66.6 0.0 3.4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KEZ35371.1 - 0.005 15.4 0.5 0.028 12.9 0.4 2.0 1 1 1 2 2 2 1 Cellulose synthase DUF2684 PF10885.8 KEZ35371.1 - 0.053 13.7 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) Acyl_transf_3 PF01757.22 KEZ35373.1 - 1.3e-24 86.9 17.3 2.2e-24 86.2 17.3 1.3 1 0 0 1 1 1 1 Acyltransferase family AP_endonuc_2 PF01261.24 KEZ35373.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_26 PF02156.15 KEZ35374.1 - 1.7e-16 60.5 2.0 2.2e-16 60.2 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 PMT PF02366.18 KEZ35375.1 - 3.9e-05 23.4 10.4 7.1e-05 22.5 10.4 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 KEZ35375.1 - 4.6e-05 23.7 13.2 4.6e-05 23.7 13.2 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Polyketide_cyc2 PF10604.9 KEZ35376.1 - 1.3e-13 51.5 2.0 1.5e-13 51.3 2.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KEZ35376.1 - 2.3e-05 24.6 0.5 3e-05 24.2 0.5 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KEZ35376.1 - 0.059 13.6 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein DUF2568 PF10823.8 KEZ35377.1 - 1.4e-22 79.8 19.4 1.7e-22 79.5 19.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) DUF3099 PF11298.8 KEZ35377.1 - 5.2 7.3 12.8 3.9 7.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) rve PF00665.26 KEZ35378.1 - 3.1e-13 50.0 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain BATS PF06968.13 KEZ35380.1 - 6.5e-15 55.1 0.0 1.6e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KEZ35380.1 - 2.4e-12 47.5 0.1 6.3e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily AAA_26 PF13500.6 KEZ35381.1 - 6.3e-32 111.0 0.0 7.7e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ35381.1 - 1.2e-05 25.4 0.0 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Indigoidine_A PF04227.12 KEZ35381.1 - 0.026 13.9 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein DUF1611 PF07755.11 KEZ35381.1 - 0.081 12.2 2.3 1.9 7.7 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain ArsA_ATPase PF02374.15 KEZ35381.1 - 0.16 11.1 0.2 0.62 9.2 1.0 1.5 2 0 0 2 2 2 0 Anion-transporting ATPase Aminotran_1_2 PF00155.21 KEZ35382.1 - 3.9e-51 174.3 0.0 4.6e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ35382.1 - 3.3e-08 32.5 0.1 4.7e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ35382.1 - 1.1e-05 25.0 6.7 1.7e-05 24.3 6.7 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEZ35382.1 - 3.9e-05 22.8 0.2 5.8e-05 22.2 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 KEZ35382.1 - 0.03 12.9 1.5 0.38 9.3 1.5 2.0 1 1 0 1 1 1 0 Serine hydroxymethyltransferase OKR_DC_1 PF01276.20 KEZ35382.1 - 0.038 12.7 0.1 0.21 10.3 0.1 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 KEZ35382.1 - 0.056 12.7 0.5 0.12 11.6 0.5 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase H_kinase_N PF12282.8 KEZ35383.1 - 1.8e-51 173.9 1.9 1.8e-51 173.8 0.1 1.9 2 1 1 3 3 3 1 Signal transduction histidine kinase HisKA_2 PF07568.12 KEZ35383.1 - 1.1e-22 79.9 1.4 2.1e-22 79.0 1.4 1.5 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 KEZ35383.1 - 4.7e-11 43.2 0.0 2.9e-10 40.7 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 KEZ35383.1 - 2.4e-07 31.3 1.7 7.2e-07 29.8 1.7 1.8 1 0 0 1 1 1 1 HWE histidine kinase HATPase_c_2 PF13581.6 KEZ35383.1 - 5.9e-07 29.5 0.1 2.9e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KEZ35383.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Whib PF02467.16 KEZ35384.1 - 2.2e-26 92.2 2.3 2.5e-26 92.0 2.3 1.1 1 0 0 1 1 1 1 Transcription factor WhiB GDPD PF03009.17 KEZ35385.1 - 1.6e-23 83.8 0.0 1.7e-21 77.1 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DAGK_cat PF00781.24 KEZ35386.1 - 2.6e-23 82.0 0.4 3.7e-23 81.5 0.4 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 KEZ35386.1 - 0.013 15.8 0.0 7.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase accessory domain NAD_kinase PF01513.21 KEZ35386.1 - 0.018 14.2 0.8 0.037 13.2 0.8 1.5 1 1 0 1 1 1 0 ATP-NAD kinase Sigma70_r2 PF04542.14 KEZ35388.1 - 5.3e-21 74.2 0.0 1.1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KEZ35388.1 - 2.5e-17 62.1 3.8 1e-15 57.0 2.1 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 KEZ35388.1 - 3.2e-17 62.4 1.4 7.5e-16 58.0 0.6 2.3 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 KEZ35388.1 - 4.4e-11 42.3 3.7 5.8e-10 38.7 0.5 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 MarR_2 PF12802.7 KEZ35388.1 - 4.7e-06 26.4 0.2 0.022 14.7 0.1 2.8 2 0 0 2 2 2 2 MarR family HTH_23 PF13384.6 KEZ35388.1 - 4.9e-06 26.2 0.5 0.00039 20.1 0.1 3.2 4 0 0 4 4 2 1 Homeodomain-like domain MarR PF01047.22 KEZ35388.1 - 0.00024 21.0 0.2 0.0051 16.7 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 KEZ35388.1 - 0.00027 20.8 0.1 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family Sigma70_ECF PF07638.11 KEZ35388.1 - 0.0032 17.4 0.1 0.017 15.0 0.1 1.9 1 1 0 2 2 2 1 ECF sigma factor HTH_3 PF01381.22 KEZ35388.1 - 0.0048 16.9 0.7 0.043 13.9 0.1 2.8 3 1 1 4 4 4 1 Helix-turn-helix HTH_28 PF13518.6 KEZ35388.1 - 0.0051 16.9 0.0 0.88 9.7 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ35388.1 - 0.0073 15.8 0.1 0.071 12.7 0.0 2.5 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KEZ35388.1 - 0.011 15.7 2.2 0.031 14.3 0.2 2.5 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ35388.1 - 0.016 14.6 0.1 3.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Phage_antitermQ PF06530.12 KEZ35388.1 - 0.036 14.0 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q YdaS_antitoxin PF15943.5 KEZ35388.1 - 0.037 13.9 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT GerE PF00196.19 KEZ35388.1 - 0.041 13.4 0.0 0.53 9.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family IF2_N PF04760.15 KEZ35388.1 - 0.048 13.5 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_10 PF04967.12 KEZ35388.1 - 0.052 13.4 0.7 1.7 8.5 0.1 2.9 3 0 0 3 3 3 0 HTH DNA binding domain HTH_38 PF13936.6 KEZ35388.1 - 0.056 13.2 0.6 2.6 7.9 0.0 3.1 3 1 1 4 4 3 0 Helix-turn-helix domain HTH_AraC PF00165.23 KEZ35388.1 - 0.065 13.4 0.2 2.3 8.4 0.0 3.0 3 1 1 4 4 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_29 PF13551.6 KEZ35388.1 - 0.087 12.9 0.1 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix KORA PF16509.5 KEZ35388.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor DUF722 PF05263.11 KEZ35388.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) KorB PF08535.10 KEZ35388.1 - 0.2 11.7 0.0 4 7.5 0.0 2.7 3 0 0 3 3 3 0 KorB domain HTH_37 PF13744.6 KEZ35388.1 - 0.26 11.2 1.9 0.8 9.7 0.1 2.5 3 1 0 3 3 3 0 Helix-turn-helix domain HATPase_c_2 PF13581.6 KEZ35389.1 - 0.00047 20.1 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Acetyltransf_1 PF00583.25 KEZ35390.1 - 2.3e-16 60.1 0.0 2.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ35390.1 - 7.1e-10 39.2 0.0 1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ35390.1 - 3.5e-07 30.1 0.0 6.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KEZ35390.1 - 1.1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ35390.1 - 0.0043 17.1 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEZ35390.1 - 0.025 14.7 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KEZ35390.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 KEZ35390.1 - 0.1 13.3 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain dTDP_sugar_isom PF00908.17 KEZ35391.1 - 1.2e-54 184.5 0.0 1.5e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase SBP_bac_3 PF00497.20 KEZ35391.1 - 0.0044 16.5 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 malic PF00390.19 KEZ35392.1 - 9.9e-29 100.4 0.1 5.7e-26 91.4 0.1 2.5 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KEZ35392.1 - 5.8e-21 74.9 5.7 3.6e-19 69.1 5.7 2.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 KEZ35392.1 - 0.0025 17.6 0.3 0.0042 16.8 0.3 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 KEZ35392.1 - 0.018 14.4 1.9 0.04 13.3 1.9 1.5 1 0 0 1 1 1 0 ThiF family Ribosomal_L18p PF00861.22 KEZ35392.1 - 0.18 12.1 4.4 3.4 8.1 0.2 2.3 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast LEAP-2 PF07359.11 KEZ35393.1 - 0.081 12.8 1.7 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) ADH_zinc_N PF00107.26 KEZ35394.1 - 7.6e-22 77.7 0.1 1.4e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ35394.1 - 4e-14 53.8 0.1 1.2e-13 52.2 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ35394.1 - 6.3e-06 26.0 0.0 0.00042 20.2 0.0 3.1 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain RHH_1 PF01402.21 KEZ35395.1 - 0.077 13.0 0.0 8.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family E1_dh PF00676.20 KEZ35396.1 - 6.3e-60 202.7 0.4 1.3e-59 201.7 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KEZ35396.1 - 2.5e-55 186.9 0.0 4.3e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain 2-oxoacid_dh PF00198.23 KEZ35396.1 - 8.9e-51 172.6 0.2 1.4e-50 171.9 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) OxoGdeHyase_C PF16870.5 KEZ35396.1 - 7.8e-41 139.3 0.0 1.4e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KEZ35396.1 - 1e-08 34.6 0.3 2.9e-08 33.2 0.3 1.8 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus AIRS PF00586.24 KEZ35397.1 - 2.5e-20 72.9 2.9 2.5e-20 72.9 2.9 2.1 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 KEZ35397.1 - 1.3e-05 25.3 0.2 1.3e-05 25.3 0.2 2.6 4 1 1 5 5 5 1 AIR synthase related protein, C-terminal domain FmdA_AmdA PF03069.15 KEZ35398.1 - 3.3e-20 72.3 0.0 6e-12 45.1 0.0 2.4 1 1 1 2 2 2 2 Acetamidase/Formamidase family MTES_1575 PF18741.1 KEZ35399.1 - 5.1e-22 77.9 0.0 9.5e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 AAA_30 PF13604.6 KEZ35399.1 - 1.9e-13 50.5 0.2 5e-08 32.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KEZ35399.1 - 3.6e-12 46.3 0.0 1.8e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KEZ35399.1 - 2.7e-09 37.2 0.3 3.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEZ35399.1 - 4.1e-08 33.7 0.3 0.00084 19.7 0.0 3.4 3 1 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ35399.1 - 0.0001 22.1 0.0 0.66 9.7 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KEZ35399.1 - 0.0013 18.7 0.0 0.0081 16.0 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 KEZ35399.1 - 0.0045 16.5 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KEZ35399.1 - 0.0079 16.6 0.2 0.0079 16.6 0.2 4.9 6 0 0 6 6 5 1 AAA ATPase domain IstB_IS21 PF01695.17 KEZ35399.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KEZ35399.1 - 0.018 15.3 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KEZ35399.1 - 0.018 14.5 0.0 0.065 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein UvrD_C_2 PF13538.6 KEZ35399.1 - 0.019 14.8 0.1 0.079 12.8 0.1 2.1 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KEZ35399.1 - 0.022 14.0 0.0 0.063 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KEZ35399.1 - 0.032 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 KEZ35399.1 - 0.076 13.0 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KEZ35399.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KEZ35399.1 - 0.11 11.5 0.3 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF559 PF04480.12 KEZ35399.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) AAA_33 PF13671.6 KEZ35399.1 - 0.49 10.6 2.8 0.57 10.3 0.2 2.6 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KEZ35400.1 - 1.4e-55 189.0 0.0 2.2e-32 112.8 0.0 2.1 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KEZ35400.1 - 8.4e-43 146.2 0.1 2.9e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 KEZ35400.1 - 1.4e-28 100.3 0.0 5.1e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KEZ35400.1 - 5.2e-08 32.6 0.5 0.00014 21.6 0.1 2.9 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ35400.1 - 2.6e-05 24.0 2.3 0.00051 19.8 0.3 2.8 2 1 0 2 2 2 1 AAA domain Methyltransf_11 PF08241.12 KEZ35401.1 - 2.4e-14 53.7 0.0 5.7e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35401.1 - 8.8e-10 38.7 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ35401.1 - 1.4e-08 35.3 0.0 5.3e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35401.1 - 2.3e-08 34.7 0.0 9.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ35401.1 - 0.016 15.0 0.0 0.097 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ35401.1 - 0.017 14.5 0.0 0.06 12.7 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Aminotran_1_2 PF00155.21 KEZ35402.1 - 2.1e-26 93.0 0.0 2.6e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEZ35402.1 - 0.00057 18.9 0.0 0.0021 17.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Leu_Phe_trans PF03588.14 KEZ35403.1 - 9.5e-53 178.2 0.0 1.7e-50 170.9 0.0 2.1 2 0 0 2 2 2 2 Leucyl/phenylalanyl-tRNA protein transferase EnY2 PF10163.9 KEZ35403.1 - 0.013 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor e(y)2 EAL PF00563.20 KEZ35404.1 - 2.8e-64 216.9 0.0 4.1e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KEZ35404.1 - 3.8e-45 153.5 0.0 5.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF872 PF05915.12 KEZ35404.1 - 1.3 9.2 6.0 1.9 8.7 0.1 2.9 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Zn_peptidase_2 PF04298.12 KEZ35404.1 - 3.8 6.9 6.9 0.11 11.9 0.2 1.7 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase SLATT_1 PF18181.1 KEZ35404.1 - 9.9 6.1 6.2 14 5.7 4.0 2.3 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Bac_luciferase PF00296.20 KEZ35405.1 - 1.1e-42 146.6 0.2 1.3e-42 146.3 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HTH_31 PF13560.6 KEZ35406.1 - 0.026 14.9 0.3 0.097 13.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1345 PF07077.11 KEZ35407.1 - 0.57 9.9 6.6 0.13 12.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) PMP1_2 PF08114.11 KEZ35407.1 - 0.82 9.5 6.4 1.5 8.6 1.4 2.5 2 0 0 2 2 2 0 ATPase proteolipid family DUF2127 PF09900.9 KEZ35408.1 - 6.2e-41 139.9 8.0 8.3e-41 139.5 8.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2127) TarH PF02203.15 KEZ35408.1 - 0.11 12.4 2.1 1.1 9.2 0.1 2.3 1 1 1 2 2 2 0 Tar ligand binding domain homologue DUF2637 PF10935.8 KEZ35409.1 - 0.027 14.4 4.2 0.03 14.2 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) DUF997 PF06196.12 KEZ35409.1 - 0.18 11.9 1.5 0.28 11.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) AcrZ PF10766.9 KEZ35409.1 - 0.7 9.5 4.1 0.93 9.1 3.3 1.7 1 1 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ ADIP PF11559.8 KEZ35410.1 - 0.047 13.8 0.3 0.074 13.1 0.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HTH_7 PF02796.15 KEZ35410.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Geminin PF07412.12 KEZ35410.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Geminin TetR_N PF00440.23 KEZ35410.1 - 0.17 11.7 1.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Phage_integrase PF00589.22 KEZ35411.1 - 0.0025 17.6 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ35411.1 - 0.036 14.3 0.0 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KEZ35413.1 - 2.8e-08 33.9 0.0 6.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 KEZ35413.1 - 1.8e-07 31.1 0.1 0.15 11.8 0.1 3.3 3 0 0 3 3 3 3 Phage integrase family Phage_int_SAM_4 PF13495.6 KEZ35413.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Thump_like PF18096.1 KEZ35414.1 - 0.088 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 THUMP domain-like Replic_Relax PF13814.6 KEZ35415.1 - 6.7e-40 137.2 0.3 6.7e-40 137.2 0.3 1.7 1 1 1 2 2 2 1 Replication-relaxation N6_Mtase PF02384.16 KEZ35417.1 - 6.9e-102 340.9 0.0 9.1e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 KEZ35417.1 - 8e-21 75.1 0.0 1.7e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 HsdM N-terminal domain UPF0020 PF01170.18 KEZ35417.1 - 1.1e-05 25.3 0.1 0.00021 21.1 0.0 2.6 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Eco57I PF07669.11 KEZ35417.1 - 0.00018 22.0 0.0 0.00039 20.9 0.0 1.6 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 KEZ35417.1 - 0.0031 17.1 0.0 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain AviRa PF11599.8 KEZ35417.1 - 0.0061 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_31 PF13847.6 KEZ35417.1 - 0.087 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methylase_S PF01420.19 KEZ35418.1 - 1.1e-08 35.5 0.0 0.00018 21.8 0.0 2.2 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain SWI2_SNF2 PF18766.1 KEZ35419.1 - 5.4e-53 179.9 0.0 1e-52 179.0 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 KEZ35419.1 - 9e-25 87.8 0.0 1e-23 84.3 0.0 2.2 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 KEZ35419.1 - 1.9e-15 57.3 0.0 4.6e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ35419.1 - 1.9e-07 31.0 0.0 4.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPD52 PF04201.15 KEZ35419.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Tumour protein D52 family DUF4164 PF13747.6 KEZ35419.1 - 1.9 8.8 5.0 0.8 10.0 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RHH_1 PF01402.21 KEZ35419.1 - 2.2 8.3 4.3 13 5.9 0.1 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Nterm_IS4 PF13006.7 KEZ35420.1 - 9.5e-16 57.8 0.0 1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Insertion element 4 transposase N-terminal Hemerythrin PF01814.23 KEZ35421.1 - 1.2e-09 38.8 12.5 1.2e-09 38.8 12.5 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain RdRP_3 PF00998.23 KEZ35421.1 - 0.035 12.8 0.2 0.039 12.7 0.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Gp49 PF05973.14 KEZ35421.1 - 0.067 13.3 0.2 0.5 10.5 0.1 2.1 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) cNMP_binding PF00027.29 KEZ35422.1 - 7e-17 61.3 0.2 1.3e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Terpene_synth_C PF03936.16 KEZ35423.1 - 0.00075 18.9 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Nitroreductase PF00881.24 KEZ35424.1 - 3e-33 115.3 0.0 3.7e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YcaO PF02624.16 KEZ35425.1 - 9.1e-49 166.5 4.1 1.2e-48 166.1 4.1 1.1 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding YcaO PF02624.16 KEZ35426.1 - 1.3e-53 182.4 7.0 2e-53 181.8 7.0 1.2 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding BtrH_N PF14399.6 KEZ35426.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Peptidase_S15 PF02129.18 KEZ35427.1 - 4.9e-40 137.8 1.5 7.8e-40 137.2 1.5 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEZ35427.1 - 3e-20 73.1 0.4 5.9e-20 72.2 0.4 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KEZ35427.1 - 5.5e-05 22.6 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEZ35427.1 - 0.00019 21.0 0.4 0.00031 20.3 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ35427.1 - 0.00023 20.9 0.0 0.00055 19.7 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 KEZ35427.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) MFS_1 PF07690.16 KEZ35429.1 - 4.2e-20 72.0 48.3 2.3e-17 62.9 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KEZ35429.1 - 1.8e-19 69.6 40.6 2.6e-19 69.0 40.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Peripla_BP_2 PF01497.18 KEZ35430.1 - 1.4e-25 90.2 0.0 1.9e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein LPAM_2 PF13627.6 KEZ35430.1 - 1.5 8.8 5.1 4.1 7.4 5.1 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ABC_tran PF00005.27 KEZ35431.1 - 1.1e-29 103.7 0.0 1.4e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ35431.1 - 8.9e-11 42.1 0.5 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ35431.1 - 6.2e-05 22.5 0.2 0.002 17.6 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ35431.1 - 0.00056 20.3 0.1 0.00089 19.7 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KEZ35431.1 - 0.0021 18.2 0.1 0.0041 17.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ35431.1 - 0.0031 17.2 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEZ35431.1 - 0.0046 16.3 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 KEZ35431.1 - 0.0049 16.6 0.2 0.02 14.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ35431.1 - 0.016 15.5 1.1 0.3 11.4 1.1 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ35431.1 - 0.022 15.2 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KEZ35431.1 - 0.032 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.6 KEZ35431.1 - 0.043 13.5 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KEZ35431.1 - 0.061 13.8 0.0 0.077 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KEZ35431.1 - 0.12 12.6 0.1 2.3 8.5 0.1 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FecCD PF01032.18 KEZ35432.1 - 1e-94 317.0 36.8 1.3e-94 316.7 36.8 1.1 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 KEZ35433.1 - 4.1e-29 101.8 0.0 7.1e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEZ35433.1 - 3e-17 63.2 7.8 4.3e-17 62.6 7.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KEZ35433.1 - 9.2e-05 22.0 1.1 0.0038 16.7 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ35433.1 - 0.01 16.3 0.4 0.075 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KEZ35433.1 - 0.023 14.6 0.3 6.6 6.6 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 KEZ35433.1 - 0.031 14.0 0.1 0.081 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEZ35433.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 KEZ35433.1 - 0.056 13.2 0.2 0.34 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane_3 PF13748.6 KEZ35433.1 - 0.062 12.5 3.9 0.61 9.3 0.1 2.5 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_22 PF13401.6 KEZ35433.1 - 0.073 13.4 1.5 1.4 9.2 1.5 2.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KEZ35433.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 KEZ35433.1 - 0.11 12.3 0.3 0.32 10.8 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KEZ35433.1 - 0.17 12.0 0.2 0.37 10.8 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Pox_A32 PF04665.12 KEZ35433.1 - 0.27 10.6 1.5 0.3 10.5 0.2 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein Lipase_C PF18067.1 KEZ35434.1 - 5.1e-29 100.7 0.1 1.2e-28 99.4 0.1 1.7 1 0 0 1 1 1 1 Lipase C-terminal domain Lipase_2 PF01674.18 KEZ35434.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 KEZ35434.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KEZ35434.1 - 0.037 13.3 0.2 0.21 10.8 0.0 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Mannosidase_ig PF17786.1 KEZ35434.1 - 0.16 12.6 0.0 0.54 10.9 0.0 1.9 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain Pep_deformylase PF01327.21 KEZ35435.1 - 1.6e-32 112.3 0.0 2.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase HTH_31 PF13560.6 KEZ35435.1 - 0.00081 19.7 0.1 0.0028 18.0 0.1 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ35435.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Transglycosylas PF06737.14 KEZ35436.1 - 1.3e-14 54.6 0.8 2e-14 54.0 0.4 1.4 1 1 0 1 1 1 1 Transglycosylase-like domain SLT PF01464.20 KEZ35436.1 - 4.1e-06 26.4 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain SpoU_methylase PF00588.19 KEZ35437.1 - 1.2e-27 96.8 0.0 1.7e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KEZ35437.1 - 2e-14 53.6 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding PP2C_2 PF13672.6 KEZ35439.1 - 1.7e-10 40.9 1.9 9.6e-10 38.4 1.9 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KEZ35439.1 - 0.00015 21.5 0.0 0.081 12.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C zinc_ribbon_2 PF13240.6 KEZ35439.1 - 0.0009 18.9 0.9 0.0017 18.0 0.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KEZ35439.1 - 0.0018 18.2 0.2 0.0043 17.0 0.2 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KEZ35439.1 - 0.014 14.7 2.0 0.032 13.6 2.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain VWA_3_C PF18571.1 KEZ35440.1 - 1e-20 73.3 2.5 1e-20 73.3 2.5 2.7 3 1 0 3 3 3 1 von Willebrand factor type A C-terminal domain FHA PF00498.26 KEZ35441.1 - 3e-11 43.5 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEZ35441.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain tRNA-synt_1e PF01406.19 KEZ35442.1 - 2.9e-104 348.7 0.0 2.5e-84 283.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KEZ35442.1 - 1.2e-12 47.3 0.0 2.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KEZ35442.1 - 4.7e-05 23.8 0.1 0.00024 21.5 0.0 2.2 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.18 KEZ35442.1 - 4.9e-05 22.4 0.0 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KEZ35442.1 - 0.0012 17.2 0.0 0.03 12.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Putative_PNPOx PF01243.20 KEZ35443.1 - 7.6e-15 54.9 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KEZ35443.1 - 0.0077 15.8 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like YgbB PF02542.16 KEZ35444.1 - 2.5e-46 157.8 0.0 2.9e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 YgbB family IspD PF01128.19 KEZ35445.1 - 1.6e-65 220.9 4.4 1.9e-65 220.7 4.4 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 KEZ35445.1 - 8.8e-13 48.9 12.4 1.4e-12 48.3 12.3 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 KEZ35445.1 - 1.9e-09 37.8 0.0 2.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase CarD_CdnL_TRCF PF02559.16 KEZ35446.1 - 1.9e-17 63.7 0.1 2.7e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 CarD-like/TRCF domain PCuAC PF04314.13 KEZ35447.1 - 0.00063 19.5 0.0 0.12 12.2 0.0 2.4 1 1 0 1 1 1 1 Copper chaperone PCu(A)C YjbE PF11106.8 KEZ35447.1 - 0.0015 18.7 7.8 0.0015 18.7 7.8 3.4 2 1 1 3 3 3 1 Exopolysaccharide production protein YjbE ATPase PF06745.13 KEZ35448.1 - 3e-16 59.5 0.0 8e-12 45.0 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 KEZ35448.1 - 1.9e-13 50.4 9.9 2.2e-13 50.2 7.3 2.4 2 2 1 3 3 3 1 AAA domain ChlI PF13541.6 KEZ35448.1 - 5.3e-09 36.0 0.1 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 KEZ35448.1 - 2.5e-08 33.7 1.5 4.3e-08 32.9 0.4 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain DnaB_C PF03796.15 KEZ35448.1 - 8.1e-08 31.9 0.0 5.2e-06 26.0 0.0 2.2 1 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA PF00004.29 KEZ35448.1 - 0.00013 22.3 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ35448.1 - 0.00018 21.9 2.0 0.00018 21.9 2.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ35448.1 - 0.0002 21.7 0.1 0.00038 20.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEZ35448.1 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.7 2 1 0 2 2 1 1 AAA domain Rad51 PF08423.11 KEZ35448.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.5 2 0 0 2 2 2 0 Rad51 NTPase_1 PF03266.15 KEZ35448.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KEZ35448.1 - 0.02 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KEZ35448.1 - 0.039 14.0 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RecA PF00154.21 KEZ35448.1 - 0.041 13.3 1.9 0.06 12.8 1.9 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 KEZ35448.1 - 0.044 14.3 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEZ35448.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KEZ35448.1 - 0.053 14.0 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KEZ35448.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KEZ35448.1 - 0.061 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KEZ35448.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEZ35448.1 - 0.09 12.1 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin PAXNEB PF05625.11 KEZ35448.1 - 0.13 11.4 0.2 0.52 9.4 0.2 1.7 2 0 0 2 2 2 0 PAXNEB protein MCM PF00493.23 KEZ35448.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain DAP3 PF10236.9 KEZ35448.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 KEZ35448.1 - 0.18 11.5 11.2 0.034 13.9 7.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEZ35448.1 - 0.22 11.8 1.8 0.37 11.1 0.4 1.9 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KEZ35448.1 - 0.26 11.2 2.4 2.9 7.7 0.0 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 DisA-linker PF10635.9 KEZ35449.1 - 7.7e-49 165.1 0.2 1.4e-48 164.2 0.2 1.5 1 0 0 1 1 1 1 DisA bacterial checkpoint controller linker region DisA_N PF02457.16 KEZ35449.1 - 9.6e-25 86.5 0.1 1.6e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding HHH_2 PF12826.7 KEZ35449.1 - 7.9e-07 29.1 0.1 2.6e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 KEZ35449.1 - 4.2e-05 23.2 0.1 0.00013 21.6 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KEZ35449.1 - 9.7e-05 22.9 0.0 0.00041 20.9 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain HhH-GPD PF00730.25 KEZ35450.1 - 5.6e-12 46.1 0.0 9.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEZ35450.1 - 1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif AbiEi_4 PF13338.6 KEZ35450.1 - 0.01 16.0 0.6 0.038 14.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin GPP34 PF05719.11 KEZ35450.1 - 0.17 11.9 4.6 3.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Trans_reg_C PF00486.28 KEZ35451.1 - 7e-24 83.7 0.1 1.2e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KEZ35451.1 - 7.1e-08 32.6 0.0 9.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain FAM176 PF14851.6 KEZ35451.1 - 0.093 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 FAM176 family ABC_tran PF00005.27 KEZ35452.1 - 5.9e-31 107.8 0.0 8.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ35452.1 - 7.7e-10 39.1 0.0 0.0009 19.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ35452.1 - 8.6e-07 28.6 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ35452.1 - 8.1e-06 26.2 0.0 1.7e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KEZ35452.1 - 0.0005 19.9 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEZ35452.1 - 0.00061 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KEZ35452.1 - 0.00077 19.2 0.1 0.0083 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KEZ35452.1 - 0.00093 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KEZ35452.1 - 0.001 19.0 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KEZ35452.1 - 0.002 18.5 0.1 0.0051 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KEZ35452.1 - 0.0037 17.8 0.0 0.0081 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ35452.1 - 0.0063 16.7 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ35452.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KEZ35452.1 - 0.032 13.0 0.0 0.92 8.2 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein PRK PF00485.18 KEZ35452.1 - 0.052 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KEZ35452.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ35452.1 - 0.2 12.1 0.1 0.62 10.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase BPD_transp_1 PF00528.22 KEZ35453.1 - 2.9e-26 92.4 16.5 2.9e-26 92.4 16.5 2.5 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KEZ35454.1 - 2.4e-14 53.5 28.6 3.7e-14 52.9 18.0 2.5 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component TcdA_TcdB_pore PF12920.7 KEZ35454.1 - 1 7.5 2.1 1.7 6.8 2.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PBP_like_2 PF12849.7 KEZ35455.1 - 6.8e-61 206.4 13.3 8.7e-61 206.1 13.3 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 KEZ35455.1 - 4.6e-10 38.9 0.0 9.6e-10 37.9 0.0 1.6 1 1 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 KEZ35455.1 - 1.6e-09 38.2 12.7 2.5e-09 37.5 12.7 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4988 PF16378.5 KEZ35455.1 - 0.13 11.9 0.7 0.24 11.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function HGTP_anticodon PF03129.20 KEZ35457.1 - 8.3e-19 67.5 0.1 3.3e-18 65.6 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEZ35457.1 - 5.6e-11 42.7 0.0 8.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AA_kinase PF00696.28 KEZ35458.1 - 8.4e-29 100.8 0.1 1.2e-28 100.4 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family CheD PF03975.13 KEZ35458.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Peripla_BP_6 PF13458.6 KEZ35459.1 - 2.6e-75 254.2 2.2 3e-75 254.0 2.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KEZ35459.1 - 9.4e-09 34.7 0.0 3e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein domain ANF_receptor PF01094.28 KEZ35459.1 - 0.00022 20.4 0.0 0.056 12.5 0.0 2.0 2 0 0 2 2 2 2 Receptor family ligand binding region UTRA PF07702.13 KEZ35460.1 - 4.4e-19 68.7 0.0 7.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 KEZ35460.1 - 5e-18 64.5 0.1 1.3e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 KEZ35460.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ35460.1 - 0.044 13.3 0.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 KEZ35460.1 - 0.15 12.0 0.0 5.9 6.9 0.0 2.4 2 0 0 2 2 2 0 MarR family FtsK_SpoIIIE PF01580.18 KEZ35466.1 - 2.3e-06 27.1 0.1 2.2e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 FtsK/SpoIIIE family DUF3989 PF13150.6 KEZ35466.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) PSI_8 PF00796.18 KEZ35466.1 - 0.59 10.0 3.7 0.31 10.9 0.9 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII GntR PF00392.21 KEZ35467.1 - 1.3e-10 40.8 0.1 2.3e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MgsA_C PF12002.8 KEZ35468.1 - 2e-69 232.8 0.1 2.7e-69 232.4 0.1 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KEZ35468.1 - 3.5e-26 91.3 0.1 1.1e-25 89.7 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KEZ35468.1 - 6.9e-15 55.6 0.0 2.2e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEZ35468.1 - 8.3e-13 48.4 0.0 2.3e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEZ35468.1 - 4.2e-06 27.2 4.3 0.0035 17.7 0.3 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KEZ35468.1 - 6.4e-06 26.2 0.1 0.00019 21.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEZ35468.1 - 3.6e-05 23.3 0.1 0.29 10.5 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ35468.1 - 0.00012 21.9 0.0 0.36 10.5 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KEZ35468.1 - 0.00018 21.8 0.6 0.093 13.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KEZ35468.1 - 0.00054 19.2 0.0 0.00082 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KEZ35468.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KEZ35468.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KEZ35468.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEZ35468.1 - 0.0019 18.2 0.0 1.5 8.7 0.0 2.4 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KEZ35468.1 - 0.0033 17.0 0.5 0.0033 17.0 0.5 2.4 2 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KEZ35468.1 - 0.0054 16.5 1.2 0.1 12.3 1.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEZ35468.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEZ35468.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ35468.1 - 0.018 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ35468.1 - 0.023 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEZ35468.1 - 0.029 14.7 0.8 0.29 11.4 1.0 2.1 1 1 1 2 2 2 0 AAA domain Glyco_hydro_3 PF00933.21 KEZ35468.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain ResIII PF04851.15 KEZ35468.1 - 0.041 13.9 0.1 2.8 7.9 0.0 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KEZ35468.1 - 0.044 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KEZ35468.1 - 0.049 12.8 0.0 0.36 10.0 0.0 2.0 1 1 1 2 2 2 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KEZ35468.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KEZ35468.1 - 0.096 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KEZ35468.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KEZ35468.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ35468.1 - 0.23 11.4 0.1 0.51 10.2 0.1 1.5 1 1 0 1 1 1 0 NTPase TPR_14 PF13428.6 KEZ35468.1 - 1 10.3 5.3 5.3 8.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF948 PF06103.11 KEZ35469.1 - 4.1e-23 81.4 1.3 6.5e-23 80.8 1.3 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KEZ35469.1 - 0.027 14.9 0.1 0.044 14.2 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 KEZ35469.1 - 0.13 12.1 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 tRNA-synt_2c PF01411.19 KEZ35471.1 - 8.2e-186 618.8 0.0 9.9e-186 618.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KEZ35471.1 - 9.7e-18 64.9 3.9 2.2e-17 63.8 1.6 2.2 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 KEZ35471.1 - 6.4e-14 51.8 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RuvX PF03652.15 KEZ35472.1 - 4.2e-37 127.5 0.2 4.9e-37 127.3 0.2 1.0 1 0 0 1 1 1 1 Holliday junction resolvase YceG PF02618.16 KEZ35473.1 - 1.3e-67 228.3 0.0 1.5e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 YceG-like family Gly-rich_Ago1 PF12764.7 KEZ35473.1 - 0.043 14.6 0.2 0.098 13.4 0.2 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut AcrZ PF10766.9 KEZ35473.1 - 0.19 11.3 0.5 0.35 10.5 0.5 1.3 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Shikimate_dh_N PF08501.11 KEZ35474.1 - 1.7e-23 82.7 0.0 2.7e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KEZ35474.1 - 3e-05 23.7 0.1 0.00011 21.9 0.1 2.1 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KEZ35474.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EspB PF05802.11 KEZ35474.1 - 0.13 12.3 1.9 1.7 8.6 0.3 2.2 2 0 0 2 2 2 0 Enterobacterial EspB protein Peptidase_A24 PF01478.18 KEZ35475.1 - 4.2e-10 40.0 9.7 4.2e-10 40.0 9.7 1.8 2 0 0 2 2 2 1 Type IV leader peptidase family Kei1 PF08552.11 KEZ35475.1 - 0.065 13.1 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Chorismate_synt PF01264.21 KEZ35476.1 - 1.4e-113 378.9 1.0 1.6e-113 378.7 1.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF1263 PF06882.12 KEZ35476.1 - 0.014 15.4 1.0 2.9 8.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) SKI PF01202.22 KEZ35477.1 - 1.6e-39 135.5 0.0 2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KEZ35477.1 - 0.00011 22.4 0.2 0.00015 22.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ35477.1 - 0.00011 22.7 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ35477.1 - 0.00083 19.8 0.7 0.0012 19.2 0.7 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KEZ35477.1 - 0.001 19.4 1.2 0.002 18.4 0.3 2.0 1 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KEZ35477.1 - 0.0027 17.4 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEZ35477.1 - 0.0049 16.5 5.5 0.022 14.3 5.5 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ35477.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEZ35477.1 - 0.016 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ35477.1 - 0.019 15.2 0.0 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KEZ35477.1 - 0.023 14.4 0.4 0.29 10.7 0.2 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 KEZ35477.1 - 0.032 13.7 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 KEZ35477.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KEZ35477.1 - 0.037 13.3 0.1 0.073 12.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin2 PF13189.6 KEZ35477.1 - 0.039 14.1 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Ploopntkinase3 PF18751.1 KEZ35477.1 - 0.063 13.2 0.6 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 6PF2K PF01591.18 KEZ35477.1 - 0.066 12.5 0.1 0.17 11.2 0.1 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 KEZ35477.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2075 PF09848.9 KEZ35477.1 - 0.073 12.3 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KEZ35477.1 - 0.077 13.4 0.1 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ35477.1 - 0.094 12.4 4.2 0.23 11.1 4.2 1.8 1 1 0 1 1 1 0 AAA domain DUF3107 PF11305.8 KEZ35477.1 - 0.094 13.0 0.7 1.1 9.5 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3107) NACHT PF05729.12 KEZ35477.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KEZ35477.1 - 0.19 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KEZ35477.1 - 0.2 12.1 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DHQ_synthase PF01761.20 KEZ35478.1 - 6.2e-91 304.2 0.0 7.9e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KEZ35478.1 - 3.4e-08 33.5 0.5 3.4e-08 33.5 0.5 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KEZ35478.1 - 8.4e-05 21.5 4.3 0.001 17.9 2.4 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Elong-fact-P_C PF09285.11 KEZ35479.1 - 4.2e-26 90.5 0.9 9.9e-26 89.3 0.2 2.0 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 KEZ35479.1 - 5.2e-26 90.5 1.1 1.2e-25 89.3 1.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 KEZ35479.1 - 8.1e-21 73.8 0.0 3.4e-20 71.8 0.0 2.0 3 0 0 3 3 3 1 Elongation factor P (EF-P) OB domain NusB PF01029.18 KEZ35480.1 - 7.8e-33 113.6 0.0 9e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 NusB family HTH_31 PF13560.6 KEZ35481.1 - 1.4e-10 41.4 1.8 4.8e-08 33.2 1.3 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 KEZ35481.1 - 1.6e-09 37.7 0.0 6.6e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix Pribosyltran PF00156.27 KEZ35482.1 - 1.1e-21 77.0 0.2 1.4e-21 76.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KEZ35482.1 - 0.056 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 KEZ35482.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase OTCace_N PF02729.21 KEZ35483.1 - 9.3e-45 152.3 0.2 1.5e-44 151.6 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KEZ35483.1 - 9.8e-23 81.0 0.0 4.9e-22 78.7 0.0 2.0 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DHOase PF12890.7 KEZ35484.1 - 6.8e-15 55.2 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Dihydro-orotase-like Amidohydro_1 PF01979.20 KEZ35484.1 - 9.9e-15 54.7 0.1 2.1e-14 53.6 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ35484.1 - 4.3e-06 26.5 1.4 0.001 18.6 0.2 2.5 2 2 0 2 2 2 2 Amidohydrolase family CPSase_sm_chain PF00988.22 KEZ35486.1 - 1.4e-49 167.2 0.0 2.1e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KEZ35486.1 - 1.6e-37 129.1 0.0 4.1e-37 127.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ35486.1 - 4.4e-08 33.1 0.0 2.3e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KEZ35486.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.14 KEZ35486.1 - 0.056 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CPSase_L_D2 PF02786.17 KEZ35487.1 - 4.7e-105 349.7 0.0 1.2e-67 227.5 0.1 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KEZ35487.1 - 1.7e-31 109.1 0.0 3.2e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KEZ35487.1 - 2.1e-15 56.7 0.0 6.4e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KEZ35487.1 - 1.1e-11 44.7 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEZ35487.1 - 4.3e-11 42.7 0.0 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KEZ35487.1 - 1.1e-10 41.3 0.0 5.5e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KEZ35487.1 - 0.00017 21.1 0.0 0.088 12.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KEZ35487.1 - 0.00081 19.5 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CoA_binding_2 PF13380.6 KEZ35487.1 - 0.0096 16.4 0.3 3.8 8.1 0.0 3.2 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 KEZ35487.1 - 0.098 12.2 0.0 3.2 7.3 0.0 2.6 2 1 0 2 2 2 0 ATP-grasp domain OMPdecase PF00215.24 KEZ35488.1 - 7.1e-34 117.3 0.0 1.5e-33 116.3 0.0 1.5 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family IMS_HHH PF11798.8 KEZ35489.1 - 0.00015 21.9 0.2 0.059 13.7 0.1 2.7 2 0 0 2 2 2 2 IMS family HHH motif HHH PF00633.23 KEZ35489.1 - 0.00059 19.6 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 KEZ35489.1 - 0.00078 19.8 0.1 0.0019 18.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S13/S18 HHH_5 PF14520.6 KEZ35489.1 - 0.0059 17.2 1.3 0.045 14.3 0.4 2.4 2 1 0 2 2 2 1 Helix-hairpin-helix domain DUF1269 PF06897.12 KEZ35489.1 - 0.06 13.6 0.1 0.076 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Guanylate_kin PF00625.21 KEZ35490.1 - 2.1e-42 144.9 0.0 2.8e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KEZ35490.1 - 0.00037 21.0 0.0 0.0014 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ35490.1 - 0.015 15.7 0.1 0.027 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KEZ35490.1 - 0.034 14.3 0.0 0.076 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ35490.1 - 0.046 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Thymidylate_kin PF02223.17 KEZ35490.1 - 0.056 13.1 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_29 PF13555.6 KEZ35490.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ35490.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb6 PF01192.22 KEZ35491.1 - 1.4e-14 53.8 0.1 1.8e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 DFP PF04127.15 KEZ35492.1 - 5.9e-61 205.6 1.2 1.7e-60 204.0 0.0 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 KEZ35492.1 - 5.1e-36 123.8 0.0 9.2e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein PTS_IIB PF02302.17 KEZ35492.1 - 0.048 14.4 0.5 17 6.2 0.2 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit PspC PF04024.12 KEZ35492.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 PspC domain S-AdoMet_synt_C PF02773.16 KEZ35493.1 - 3.8e-67 224.5 0.0 6.6e-67 223.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KEZ35493.1 - 1.6e-42 144.6 0.0 1e-41 141.9 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KEZ35493.1 - 7.1e-40 135.7 0.3 1.4e-39 134.8 0.3 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PriA_3primeBD PF17764.1 KEZ35494.1 - 1.2e-19 70.0 0.0 2.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) Auto_anti-p27 PF06677.12 KEZ35494.1 - 0.034 14.3 5.1 7 6.9 0.4 3.4 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3046 PF11248.8 KEZ35494.1 - 0.054 13.9 0.5 7.2 7.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) zinc-ribbons_6 PF07191.12 KEZ35494.1 - 0.44 10.6 3.3 0.13 12.3 0.4 1.5 2 0 0 2 2 2 0 zinc-ribbons C1_1 PF00130.22 KEZ35494.1 - 0.57 10.1 5.7 1.2 9.1 5.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KEZ35494.1 - 1.2 9.2 7.6 4.3 7.4 7.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon Formyl_trans_N PF00551.19 KEZ35495.1 - 8.6e-33 113.6 0.0 1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KEZ35495.1 - 7e-19 67.9 0.0 1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Methyltr_RsmB-F PF01189.17 KEZ35496.1 - 6.9e-40 136.8 0.0 1.3e-35 122.8 0.0 2.1 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F NusB PF01029.18 KEZ35496.1 - 1.2e-24 87.0 0.0 1.7e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 NusB family Phage_TAC_6 PF09550.10 KEZ35496.1 - 0.031 14.7 0.4 0.16 12.4 0.4 2.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Ribul_P_3_epim PF00834.19 KEZ35497.1 - 7.1e-69 231.2 0.0 8.4e-69 230.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KEZ35497.1 - 0.078 12.6 0.3 0.13 11.8 0.1 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Lum_binding PF00677.17 KEZ35498.1 - 4.9e-46 154.6 0.0 1e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DHBP_synthase PF00926.19 KEZ35499.1 - 6.4e-87 290.0 0.1 8.8e-87 289.6 0.1 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 KEZ35499.1 - 5.2e-71 237.5 0.0 8.5e-71 236.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Collagen PF01391.18 KEZ35499.1 - 0.12 12.2 9.0 0.34 10.7 9.0 1.8 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) DMRL_synthase PF00885.19 KEZ35500.1 - 5.8e-48 162.3 1.0 6.6e-48 162.1 1.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase CBP_BcsQ PF06564.12 KEZ35501.1 - 0.00012 21.6 2.2 0.00048 19.7 1.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ CbiA PF01656.23 KEZ35501.1 - 0.00017 21.6 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEZ35501.1 - 0.0041 17.0 0.0 0.08 12.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain SseB PF07179.12 KEZ35502.1 - 2.1e-16 60.3 0.2 3.7e-16 59.5 0.2 1.3 1 0 0 1 1 1 1 SseB protein N-terminal domain Esterase_phd PF10503.9 KEZ35502.1 - 0.053 13.0 4.6 0.085 12.3 4.6 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase IF3_C PF00707.22 KEZ35503.1 - 3.9e-33 113.3 0.1 7.4e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 KEZ35503.1 - 1.2e-30 105.6 0.1 2e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 KEZ35503.1 - 0.055 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Sas10 PF09368.10 KEZ35503.1 - 0.061 13.8 2.7 1.7 9.2 0.0 2.7 3 0 0 3 3 3 0 Sas10 C-terminal domain DUF4578 PF15147.6 KEZ35503.1 - 0.19 12.6 0.9 9 7.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4578) Ribosomal_L35p PF01632.19 KEZ35504.1 - 2.1e-22 79.4 4.8 2.2e-22 79.3 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 KEZ35505.1 - 2.3e-43 146.7 6.6 2.7e-43 146.4 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 DUF2058 PF09831.9 KEZ35505.1 - 0.051 13.7 0.9 0.055 13.6 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) SMC_ScpA PF02616.14 KEZ35505.1 - 0.1 12.5 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Segregation and condensation protein ScpA SpoU_methylase PF00588.19 KEZ35506.1 - 7.4e-32 110.5 0.0 1.2e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KEZ35506.1 - 6.9e-08 32.7 0.1 1.2e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Lipase_GDSL_2 PF13472.6 KEZ35506.1 - 0.025 15.0 0.1 0.041 14.3 0.1 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UPF0180 PF03698.13 KEZ35506.1 - 0.035 14.3 0.0 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) HATPase_c PF02518.26 KEZ35507.1 - 4.7e-22 78.6 0.0 9.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ35507.1 - 9.1e-16 57.7 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KEZ35507.1 - 3.1e-06 27.4 0.3 8.6e-06 26.0 0.3 1.9 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 KEZ35507.1 - 5.5e-06 26.4 0.0 1.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KEZ35507.1 - 2.9e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KEZ35507.1 - 6e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KEZ35507.1 - 0.015 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain HATPase_c_2 PF13581.6 KEZ35507.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain tRNA-synt_2d PF01409.20 KEZ35508.1 - 1.8e-94 315.8 0.0 2.2e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 KEZ35508.1 - 1.2e-13 50.7 1.1 1.5e-13 50.4 0.2 1.7 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain B3_4 PF03483.17 KEZ35509.1 - 3.5e-64 215.7 0.0 5.4e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 KEZ35509.1 - 1.2e-58 198.1 0.0 1.7e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 KEZ35509.1 - 3.9e-22 78.5 0.0 7.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain B5 PF03484.15 KEZ35509.1 - 4.7e-11 42.8 0.0 3.8e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA_bind PF01588.20 KEZ35509.1 - 7.3e-11 42.0 0.1 4.5e-10 39.5 0.1 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain Semialdhyde_dh PF01118.24 KEZ35510.1 - 6.6e-24 84.7 0.0 1.2e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KEZ35510.1 - 2e-15 57.4 0.0 3.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain RsgA_GTPase PF03193.16 KEZ35510.1 - 0.024 14.6 0.1 6.8 6.6 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase NAD_binding_10 PF13460.6 KEZ35510.1 - 0.3 11.0 2.2 0.39 10.6 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H-binding ArgJ PF01960.18 KEZ35511.1 - 2.1e-121 405.2 8.7 2.3e-121 405.1 8.7 1.0 1 0 0 1 1 1 1 ArgJ family AA_kinase PF00696.28 KEZ35512.1 - 5.9e-48 163.6 0.9 7.2e-48 163.3 0.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family Amidohydro_2 PF04909.14 KEZ35512.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Aminotran_3 PF00202.21 KEZ35513.1 - 1.6e-96 323.4 0.0 2.2e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KEZ35513.1 - 3e-06 26.7 0.0 1.5e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase OTCace PF00185.24 KEZ35514.1 - 9e-53 178.6 0.0 1.4e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KEZ35514.1 - 1e-42 145.7 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Arg_repressor_C PF02863.18 KEZ35515.1 - 1.1e-22 79.7 0.0 1.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain Arg_repressor PF01316.21 KEZ35515.1 - 9.7e-20 70.1 0.0 1.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 KEZ35515.1 - 0.11 12.8 0.8 0.88 9.9 0.1 2.1 1 1 1 2 2 2 0 Transposase Arginosuc_synth PF00764.19 KEZ35516.1 - 3.3e-171 569.8 0.0 3.8e-171 569.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KEZ35516.1 - 0.063 12.8 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Lyase_1 PF00206.20 KEZ35517.1 - 3.9e-62 210.4 0.0 4.8e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KEZ35517.1 - 8.4e-23 80.9 0.6 8.3e-22 77.7 0.0 2.5 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Pur_DNA_glyco PF02245.16 KEZ35518.1 - 5.6e-61 205.0 0.0 6.4e-61 204.8 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) DUF4096 PF13340.6 KEZ35519.1 - 7.2e-24 83.8 0.9 9.2e-24 83.5 0.9 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) HTH_Tnp_4 PF13613.6 KEZ35519.1 - 0.0015 18.2 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease SpoIIID PF12116.8 KEZ35519.1 - 0.21 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D DDE_Tnp_1_2 PF13586.6 KEZ35520.1 - 1.3e-05 25.5 0.1 1.3e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ35520.1 - 0.002 17.8 0.2 0.002 17.8 0.2 1.0 1 0 0 1 1 1 1 Transposase DDE domain DUF2786 PF10979.8 KEZ35521.1 - 4e-17 61.9 2.5 1.4e-16 60.1 2.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) BTAD PF03704.17 KEZ35522.1 - 6.3e-14 52.6 11.4 6.3e-14 52.6 11.4 3.2 3 0 0 3 3 3 1 Bacterial transcriptional activator domain AAA_22 PF13401.6 KEZ35522.1 - 1.6e-05 25.2 0.0 4.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ35522.1 - 2.6e-05 23.5 0.0 4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Trans_reg_C PF00486.28 KEZ35522.1 - 3e-05 24.0 0.0 0.00011 22.2 0.0 2.0 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal AAA_16 PF13191.6 KEZ35522.1 - 9.5e-05 22.8 4.3 9.5e-05 22.8 4.3 4.1 4 1 0 4 4 4 1 AAA ATPase domain TPR_14 PF13428.6 KEZ35522.1 - 0.00061 20.4 3.9 0.00061 20.4 3.9 9.2 7 1 2 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ35522.1 - 0.00064 20.2 13.3 0.043 14.3 2.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ35522.1 - 0.0018 18.5 1.9 0.0018 18.5 1.9 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA PF00004.29 KEZ35522.1 - 0.077 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KEZ35522.1 - 0.15 12.5 0.0 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ABC2_membrane PF01061.24 KEZ35523.1 - 2e-34 118.9 8.7 2e-34 118.9 8.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ35523.1 - 3e-13 49.6 9.6 4.3e-13 49.1 9.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEZ35523.1 - 2.5e-07 30.3 8.8 2.5e-07 30.3 8.8 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 KEZ35524.1 - 2.3e-27 96.2 0.0 3.7e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ35524.1 - 2.2e-13 50.7 0.2 7.8e-09 35.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KEZ35524.1 - 3.9e-07 30.7 0.0 6.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_22 PF13401.6 KEZ35524.1 - 7.9e-05 22.9 0.0 0.00072 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain KdpD PF02702.17 KEZ35524.1 - 0.00053 19.5 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_23 PF13476.6 KEZ35524.1 - 0.00061 20.3 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KEZ35524.1 - 0.00097 18.9 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KEZ35524.1 - 0.0026 17.3 0.0 0.059 12.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KEZ35524.1 - 0.0034 17.0 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEZ35524.1 - 0.0062 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ35524.1 - 0.0076 16.6 1.0 0.016 15.6 0.3 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KEZ35524.1 - 0.014 15.1 0.2 0.025 14.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ35524.1 - 0.024 15.1 0.1 0.23 11.9 0.1 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ35524.1 - 0.028 14.6 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KEZ35524.1 - 0.067 13.4 0.0 0.29 11.4 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KEZ35524.1 - 0.089 12.7 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KEZ35524.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KEZ35524.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain HxlR PF01638.17 KEZ35525.1 - 1.5e-21 76.0 0.0 2.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 KEZ35525.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family NAD_binding_10 PF13460.6 KEZ35526.1 - 2.2e-27 96.1 0.7 2.5e-27 95.9 0.7 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ35526.1 - 4.4e-08 33.0 0.8 6.6e-08 32.4 0.8 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ35526.1 - 1.3e-05 24.8 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEZ35526.1 - 0.0017 18.6 0.1 0.0047 17.2 0.2 1.8 2 0 0 2 2 2 1 TrkA-N domain DapB_N PF01113.20 KEZ35526.1 - 0.0093 16.1 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KEZ35526.1 - 0.011 14.9 0.2 0.025 13.7 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain CoA_binding_2 PF13380.6 KEZ35526.1 - 0.016 15.7 0.1 0.024 15.1 0.1 1.3 1 0 0 1 1 1 0 CoA binding domain PvlArgDC PF01862.16 KEZ35526.1 - 0.13 12.0 0.6 5.6 6.7 0.0 2.3 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Sulfotransfer_3 PF13469.6 KEZ35527.1 - 1.7e-43 149.6 0.0 2.5e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 KEZ35527.1 - 0.00017 21.5 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_1 PF00685.27 KEZ35527.1 - 0.00023 20.7 0.0 0.00082 18.9 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 KEZ35527.1 - 0.03 13.9 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Stf0 sulphotransferase Aminotran_1_2 PF00155.21 KEZ35528.1 - 7.2e-20 71.5 0.0 8.5e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DHquinase_I PF01487.15 KEZ35529.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.0 1 0 0 1 1 1 0 Type I 3-dehydroquinase MarR_2 PF12802.7 KEZ35530.1 - 8.6e-10 38.4 0.1 2.9e-09 36.7 0.1 2.0 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KEZ35530.1 - 1.8e-05 24.6 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KEZ35530.1 - 0.0002 21.8 0.0 0.00052 20.4 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain MFS_1 PF07690.16 KEZ35531.1 - 7.6e-51 173.1 45.4 7.6e-51 173.1 45.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ35531.1 - 4e-07 29.2 0.0 0.27 10.1 9.9 2.4 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KEZ35531.1 - 0.00025 20.1 15.3 0.00025 20.1 15.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ35531.1 - 0.18 10.2 24.6 0.33 9.3 2.6 2.7 1 1 2 3 3 3 0 Fungal trichothecene efflux pump (TRI12) PPDK_N PF01326.19 KEZ35532.1 - 7.6e-27 94.4 0.0 9.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain HTH_IclR PF09339.10 KEZ35533.1 - 4e-10 39.3 0.0 4e-10 39.3 0.0 2.7 3 0 0 3 3 3 1 IclR helix-turn-helix domain IclR PF01614.18 KEZ35533.1 - 1.1e-06 28.6 0.3 2.1e-05 24.3 0.3 2.4 1 1 0 1 1 1 1 Bacterial transcriptional regulator MarR_2 PF12802.7 KEZ35533.1 - 2.2e-05 24.3 0.0 0.0001 22.1 0.0 2.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KEZ35533.1 - 0.00057 19.4 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KEZ35533.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LGFP PF08310.11 KEZ35534.1 - 1.2e-07 32.1 5.8 1.3e-05 25.6 1.9 2.9 3 1 0 3 3 3 2 LGFP repeat COX1 PF00115.20 KEZ35536.1 - 1.4e-148 495.4 58.4 1.6e-148 495.2 58.4 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I FCD PF07729.12 KEZ35537.1 - 9e-09 35.8 0.2 1.4e-08 35.2 0.2 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KEZ35537.1 - 5.4e-08 32.4 0.2 1.1e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FAD-oxidase_C PF02913.19 KEZ35538.1 - 2.2e-50 171.6 0.2 4.4e-50 170.6 0.2 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ35538.1 - 1.4e-26 92.9 1.9 3e-26 91.8 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 KEZ35538.1 - 1.3e-08 35.2 2.4 2.8e-08 34.1 2.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KEZ35538.1 - 1.9e-08 34.7 4.0 4.4e-08 33.6 4.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ35538.1 - 9.6e-08 32.5 3.2 2e-07 31.4 3.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ35538.1 - 2.1e-07 31.8 2.2 4e-07 30.9 2.2 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KEZ35538.1 - 4e-06 26.9 0.9 0.029 14.5 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ35538.1 - 4e-05 23.7 3.2 0.00014 21.9 3.5 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KEZ35538.1 - 0.00027 20.6 10.9 0.00094 18.9 3.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain CCG PF02754.16 KEZ35538.1 - 0.0031 17.7 0.8 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 Cysteine-rich domain Fer4_2 PF12797.7 KEZ35538.1 - 0.0082 16.2 11.5 0.017 15.2 3.8 2.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_20 PF14691.6 KEZ35538.1 - 0.031 14.1 1.7 0.096 12.5 0.0 2.2 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 KEZ35538.1 - 0.19 11.9 5.7 0.9 9.7 1.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ35538.1 - 0.23 11.6 12.7 0.36 11.0 4.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KEZ35538.1 - 2 9.1 11.2 0.11 13.0 2.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ABM PF03992.16 KEZ35539.1 - 5.7e-18 64.8 0.3 7e-18 64.5 0.3 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TPR_9 PF13371.6 KEZ35539.1 - 0.0059 16.7 0.2 0.014 15.5 0.2 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat HxlR PF01638.17 KEZ35540.1 - 3.5e-27 94.1 0.1 4.2e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 KEZ35540.1 - 0.0071 16.3 0.2 0.022 14.7 0.1 1.8 2 0 0 2 2 2 1 MarR family AbiEi_4 PF13338.6 KEZ35540.1 - 0.01 15.9 0.9 0.042 14.0 0.3 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_20 PF12840.7 KEZ35540.1 - 0.042 13.9 0.3 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.16 KEZ35541.1 - 2.4e-56 191.2 52.1 3.5e-54 184.1 51.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ35541.1 - 0.068 12.0 24.2 0.018 13.9 11.6 2.4 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ35541.1 - 2.8 6.7 17.5 3 6.6 1.6 2.3 2 0 0 2 2 2 0 MFS_1 like family OATP PF03137.20 KEZ35541.1 - 2.9 6.1 4.1 17 3.6 0.2 2.7 2 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family HTS PF04204.16 KEZ35544.1 - 2.4e-38 131.8 0.0 3.2e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Homoserine O-succinyltransferase Lipase_GDSL_2 PF13472.6 KEZ35544.1 - 0.058 13.8 0.8 4.8 7.5 0.2 2.8 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family FR47 PF08445.10 KEZ35545.1 - 0.002 18.1 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KEZ35545.1 - 0.004 17.1 0.0 0.0054 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ35545.1 - 0.054 13.7 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4410 PF14366.6 KEZ35545.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Haem_oxygenas_2 PF14518.6 KEZ35546.1 - 1.2e-33 116.4 1.6 1.5e-33 116.0 1.6 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme Cys_Met_Meta_PP PF01053.20 KEZ35547.1 - 4.6e-122 407.2 0.0 5.2e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEZ35547.1 - 1.4e-06 27.7 0.0 2.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEZ35547.1 - 0.00014 21.3 0.2 0.00027 20.3 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEZ35547.1 - 0.00043 19.4 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ35547.1 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase PALP PF00291.25 KEZ35547.1 - 0.044 13.2 1.7 2.6 7.4 0.3 2.4 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme Met_gamma_lyase PF06838.11 KEZ35547.1 - 0.051 12.1 0.0 0.092 11.2 0.0 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase MFS_1 PF07690.16 KEZ35548.1 - 1.6e-26 93.1 58.5 5.3e-18 65.1 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ35548.1 - 5.4e-06 25.5 14.4 0.00036 19.5 14.1 2.3 1 1 0 1 1 1 1 MFS_1 like family RhodobacterPufX PF11511.8 KEZ35548.1 - 7.2 6.3 10.1 1 9.0 0.2 3.4 3 0 0 3 3 3 0 Intrinsic membrane protein PufX HTH_18 PF12833.7 KEZ35549.1 - 4.8e-15 55.6 0.7 8.2e-15 54.9 0.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 KEZ35549.1 - 1.4e-14 54.2 0.1 2e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 KEZ35549.1 - 2.7e-09 36.9 0.0 1.6e-07 31.3 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family HD PF01966.22 KEZ35550.1 - 2e-05 24.8 1.8 2.9e-05 24.3 1.8 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KEZ35550.1 - 0.00059 19.6 0.7 0.00089 19.0 0.7 1.3 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 KEZ35550.1 - 0.0012 18.4 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HDOD PF08668.12 KEZ35550.1 - 0.021 14.3 0.9 0.047 13.2 0.3 1.7 1 1 1 2 2 2 0 HDOD domain PhyH PF05721.13 KEZ35551.1 - 1.2e-24 87.8 0.0 1.8e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Gpr1_Fun34_YaaH PF01184.19 KEZ35552.1 - 2.5e-14 53.4 12.3 3.1e-14 53.1 12.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DIOX_N PF14226.6 KEZ35553.1 - 1.3e-27 96.9 0.0 2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ35553.1 - 7.9e-21 74.4 0.0 2.7e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Meth_synt_2 PF01717.18 KEZ35554.1 - 3.8e-17 62.6 0.2 9.1e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEZ35554.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain PQQ_2 PF13360.6 KEZ35555.1 - 4.2e-19 69.1 6.4 5.1e-11 42.6 0.2 3.1 2 1 0 3 3 3 2 PQQ-like domain Metallophos PF00149.28 KEZ35555.1 - 4.1e-13 50.3 1.1 1.5e-12 48.5 0.3 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ35555.1 - 5.5e-07 29.9 2.5 3.6e-06 27.3 2.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PQQ PF01011.21 KEZ35555.1 - 1.3e-06 28.1 9.2 0.0057 16.5 0.0 4.8 4 0 0 4 4 4 3 PQQ enzyme repeat MetallophosN PF16371.5 KEZ35555.1 - 0.001 19.3 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 N terminal of Calcineurin-like phosphoesterase PQQ_3 PF13570.6 KEZ35555.1 - 0.0069 16.8 33.1 0.16 12.5 0.4 7.6 8 1 0 8 8 8 3 PQQ-like domain SpoIIE PF07228.12 KEZ35556.1 - 4.2e-42 144.2 2.4 4.2e-42 144.2 2.4 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PAS_4 PF08448.10 KEZ35556.1 - 2e-18 66.6 0.6 6.7e-18 65.0 0.1 2.3 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KEZ35556.1 - 4.6e-07 29.8 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 KEZ35556.1 - 9.3e-07 29.2 1.1 1.4e-05 25.4 0.1 2.8 2 1 1 3 3 3 1 GAF domain PAS_9 PF13426.7 KEZ35556.1 - 1.7e-06 28.2 0.0 4.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 KEZ35556.1 - 1e-05 25.5 0.0 3.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 KEZ35556.1 - 5.8e-05 23.0 0.0 0.00019 21.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 KEZ35556.1 - 0.00058 20.5 0.0 0.0028 18.3 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KEZ35556.1 - 0.0008 19.8 0.2 0.0068 16.8 0.1 2.5 2 1 0 2 2 2 1 GAF domain PAS_7 PF12860.7 KEZ35556.1 - 0.003 17.7 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold HATPase_c PF02518.26 KEZ35556.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Trypsin_2 PF13365.6 KEZ35557.1 - 2.1e-33 116.3 4.6 2.1e-33 116.3 4.6 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KEZ35557.1 - 2.9e-16 59.5 0.1 8.4e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KEZ35557.1 - 4e-10 39.4 2.6 4.4e-10 39.2 0.1 2.5 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 KEZ35557.1 - 7e-08 32.5 0.1 1.4e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 Trypsin PDZ PF00595.24 KEZ35557.1 - 8.3e-06 26.1 0.0 2.2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KEZ35557.1 - 0.15 10.7 0.6 0.54 8.8 0.2 1.8 2 0 0 2 2 2 0 Peptidase S46 MR_MLE_C PF13378.6 KEZ35558.1 - 7.7e-55 185.8 1.2 1.1e-54 185.3 1.2 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEZ35558.1 - 8.3e-12 45.4 0.9 2.2e-11 44.0 0.9 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KEZ35558.1 - 0.0064 15.7 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus CsbD PF05532.12 KEZ35560.1 - 6.2e-06 26.0 11.0 6.2e-06 26.0 11.0 1.8 2 0 0 2 2 2 1 CsbD-like adh_short PF00106.25 KEZ35561.1 - 8.9e-43 146.0 0.7 8.9e-43 146.0 0.7 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ35561.1 - 1e-26 94.0 1.0 1.5e-26 93.4 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ35561.1 - 1.6e-11 44.4 0.6 3.9e-11 43.2 0.6 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEZ35561.1 - 0.027 13.9 0.1 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ35561.1 - 0.29 10.7 1.1 0.48 9.9 1.1 1.3 1 0 0 1 1 1 0 NmrA-like family FAD-oxidase_C PF02913.19 KEZ35562.1 - 7.4e-45 153.5 0.0 1.3e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ35562.1 - 9e-35 119.4 0.3 2.2e-34 118.2 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 KEZ35562.1 - 3.6e-10 40.1 1.1 7.6e-10 39.1 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ35562.1 - 3.1e-08 34.1 0.9 5.9e-08 33.1 0.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain CCG PF02754.16 KEZ35562.1 - 0.00012 22.2 0.0 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 Cysteine-rich domain Fer4_7 PF12838.7 KEZ35562.1 - 0.0073 16.9 1.9 0.018 15.7 1.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEZ35562.1 - 0.088 12.9 4.6 0.53 10.4 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF2254 PF10011.9 KEZ35564.1 - 3.3e-113 378.2 5.6 3.8e-113 378.0 5.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF4131 PF13567.6 KEZ35564.1 - 0.031 13.9 7.3 0.21 11.2 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MgtE PF01769.16 KEZ35564.1 - 6.7 7.1 12.3 1.3 9.5 6.4 2.1 1 1 1 2 2 2 0 Divalent cation transporter EMP70 PF02990.16 KEZ35564.1 - 9.3 4.8 7.1 13 4.3 7.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Response_reg PF00072.24 KEZ35565.1 - 2.5e-07 30.9 0.0 2.5e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain ketoacyl-synt PF00109.26 KEZ35566.1 - 7.6e-69 232.1 0.0 1.3e-68 231.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ35566.1 - 1.8e-39 134.4 0.4 6.9e-39 132.5 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEZ35566.1 - 2.6e-20 73.0 0.0 4.2e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEZ35566.1 - 3.9e-13 49.5 0.3 7.8e-13 48.6 0.3 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 KEZ35566.1 - 0.0013 18.3 0.2 0.0023 17.5 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.23 KEZ35566.1 - 0.035 13.5 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain T3SS_ExsE PF18286.1 KEZ35566.1 - 1.8 8.5 4.2 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Type III secretion system ExsE AMP-binding PF00501.28 KEZ35568.1 - 7.1e-96 321.4 0.0 8.6e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ35568.1 - 7.2e-15 55.7 0.0 1.9e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ35568.1 - 1.1e-14 54.6 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site DDE_Tnp_1_2 PF13586.6 KEZ35569.1 - 9e-11 42.0 1.5 1.9e-10 40.9 1.5 1.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ35569.1 - 1.2e-06 28.4 4.3 1.8e-05 24.5 4.3 2.0 1 1 0 1 1 1 1 Transposase DDE domain PHF12_MRG_bd PF16737.5 KEZ35570.1 - 0.035 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain DUF664 PF04978.12 KEZ35571.1 - 2.1e-49 167.8 0.7 2.4e-49 167.6 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KEZ35571.1 - 6.3e-09 36.4 0.4 8e-09 36.1 0.4 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 KEZ35571.1 - 0.00043 20.3 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.8 KEZ35571.1 - 0.00058 20.6 3.5 0.00079 20.1 3.5 1.3 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DDE_Tnp_Tn3 PF01526.17 KEZ35572.1 - 2e-22 79.5 0.0 2.5e-17 62.8 0.0 2.0 1 1 1 2 2 2 2 Tn3 transposase DDE domain NAPRTase_C PF17956.1 KEZ35572.1 - 0.19 12.2 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF3382 PF11862.8 KEZ35573.1 - 0.12 12.7 4.4 0.07 13.4 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) HisKA_7TM PF16927.5 KEZ35573.1 - 0.15 12.1 5.6 0.083 12.9 3.5 1.6 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase MTHFR PF02219.17 KEZ35574.1 - 7e-11 42.0 0.0 7.8e-08 32.0 0.0 2.0 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase FGE-sulfatase PF03781.16 KEZ35576.1 - 1e-40 140.0 10.6 1.9e-39 135.8 10.6 2.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 TetR_N PF00440.23 KEZ35577.1 - 1.5e-13 50.3 0.0 2.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 KEZ35577.1 - 0.0072 17.1 0.9 0.0072 17.1 0.9 2.2 3 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain HBM PF16591.5 KEZ35578.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.0 1 0 0 1 1 1 0 Helical bimodular sensor domain MDMPI_N PF11716.8 KEZ35579.1 - 5.5e-14 53.0 8.2 5.5e-14 53.0 8.2 2.1 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 KEZ35579.1 - 0.00081 19.9 0.5 0.0013 19.2 0.5 1.4 1 0 0 1 1 1 1 DinB superfamily DprA_WH PF17782.1 KEZ35579.1 - 0.16 12.1 0.6 0.16 12.1 0.6 2.8 4 0 0 4 4 4 0 DprA winged helix domain DUF2599 PF10783.9 KEZ35580.1 - 4.9e-06 27.1 0.0 8.3e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2599) Transgly_assoc PF04226.13 KEZ35581.1 - 6.7e-10 39.1 12.0 1.1e-09 38.3 9.9 1.9 2 0 0 2 2 2 1 Transglycosylase associated protein FecCD PF01032.18 KEZ35581.1 - 0.01 14.8 3.9 0.013 14.5 3.9 1.1 1 0 0 1 1 1 0 FecCD transport family CRCB PF02537.15 KEZ35581.1 - 0.038 14.3 1.0 0.051 13.9 0.9 1.3 1 1 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) DUF2104 PF09877.9 KEZ35581.1 - 0.052 13.8 0.5 0.052 13.8 0.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) DUF4235 PF14019.6 KEZ35581.1 - 0.18 11.9 5.5 9.7 6.4 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) DUF5518 PF17647.1 KEZ35581.1 - 0.26 11.4 11.6 0.55 10.4 11.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5518) SNARE_assoc PF09335.11 KEZ35581.1 - 0.62 10.6 7.0 0.7 10.4 2.5 2.1 1 1 1 2 2 2 0 SNARE associated Golgi protein Trep_Strep PF09605.10 KEZ35581.1 - 0.67 9.9 7.5 0.79 9.7 0.4 2.8 2 1 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Gly-zipper_Omp PF13488.6 KEZ35581.1 - 8.1 6.5 9.2 2.3 8.3 3.6 2.5 2 1 0 2 2 2 0 Glycine zipper MttA_Hcf106 PF02416.16 KEZ35582.1 - 1.7e-20 72.1 0.0 1.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family DEC-1_N PF04625.13 KEZ35582.1 - 0.72 8.8 5.1 0.76 8.7 5.1 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Phage_integrase PF00589.22 KEZ35583.1 - 7.2e-13 48.7 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ35583.1 - 3.6e-07 30.4 0.4 2.1e-06 27.9 0.1 2.2 2 1 1 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KEZ35583.1 - 0.00018 21.9 0.0 0.00027 21.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain MTH865 PF07747.11 KEZ35584.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 1 1 2 2 2 0 MTH865-like family zf-BED PF02892.15 KEZ35585.1 - 0.11 12.6 0.3 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.26 KEZ35585.1 - 2.1 8.9 7.2 25 5.6 7.2 2.1 1 1 0 1 1 1 0 Zinc finger, C2H2 type Guanylate_cyc PF00211.20 KEZ35586.1 - 6.8e-21 74.7 0.0 1.9e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pentapeptide PF00805.22 KEZ35587.1 - 1.1e-16 60.0 8.4 1.2e-11 44.0 1.4 2.8 2 1 1 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KEZ35587.1 - 0.00013 22.0 0.0 0.0013 18.9 0.0 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 KEZ35587.1 - 0.00061 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) AAA_lid_2 PF17863.1 KEZ35588.1 - 3.2e-16 58.9 4.9 9.5e-16 57.4 4.1 2.4 1 1 0 1 1 1 1 AAA lid domain VWA_2 PF13519.6 KEZ35588.1 - 9.6e-14 51.9 0.0 2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 KEZ35588.1 - 6.8e-10 38.7 0.3 3e-07 30.0 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA PF00092.28 KEZ35588.1 - 4.2e-09 36.9 0.0 6.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 KEZ35588.1 - 2.6e-06 27.5 0.0 0.0043 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MCM PF00493.23 KEZ35588.1 - 0.0041 16.3 0.0 0.078 12.1 0.0 2.5 2 1 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 KEZ35588.1 - 0.027 14.9 1.1 0.094 13.1 0.4 2.3 2 1 0 2 2 2 0 AAA ATPase domain CobA_CobO_BtuR PF02572.15 KEZ35589.1 - 7e-58 195.7 0.0 7.9e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP GATase_3 PF07685.14 KEZ35590.1 - 2e-23 83.0 0.0 1.8e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 KEZ35590.1 - 1.8e-18 66.8 0.0 2.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KEZ35590.1 - 5.2e-14 52.5 0.1 2.5e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain SNO PF01174.19 KEZ35590.1 - 0.00038 20.4 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family DJ-1_PfpI PF01965.24 KEZ35590.1 - 0.0004 20.2 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Fer4_NifH PF00142.18 KEZ35590.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.14 KEZ35590.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KEZ35590.1 - 0.25 11.0 3.1 5.1 6.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain CbiG_C PF01890.16 KEZ35591.1 - 2.9e-29 102.0 0.3 3.3e-29 101.8 0.3 1.0 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus RPE65 PF03055.15 KEZ35593.1 - 5.2e-20 72.1 0.0 7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAD_binding_3 PF01494.19 KEZ35594.1 - 1.6e-11 44.1 1.3 5.6e-11 42.3 1.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ35594.1 - 7.3e-06 25.8 2.0 0.0081 15.8 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 KEZ35594.1 - 0.0048 16.0 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 KEZ35594.1 - 0.006 15.7 0.5 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEZ35594.1 - 0.0069 16.6 0.3 0.043 14.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ35594.1 - 0.012 14.9 0.0 0.04 13.1 0.0 1.6 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ35594.1 - 0.052 12.9 3.3 0.043 13.2 0.3 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KEZ35594.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KEZ35594.1 - 0.17 10.5 0.0 0.84 8.3 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein Polyketide_cyc2 PF10604.9 KEZ35595.1 - 0.024 14.9 8.5 0.022 15.1 7.0 1.9 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport HTH_31 PF13560.6 KEZ35596.1 - 9.2e-12 45.1 2.9 9.2e-12 45.1 2.9 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ35596.1 - 3.4e-09 36.6 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 KEZ35596.1 - 0.00036 20.9 0.0 0.00052 20.4 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_AsnC-type PF13404.6 KEZ35596.1 - 0.0026 17.6 2.1 0.16 11.8 0.4 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_19 PF12844.7 KEZ35596.1 - 0.0034 17.4 0.0 0.005 16.8 0.0 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KEZ35596.1 - 0.0046 17.0 0.3 0.26 11.5 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ35596.1 - 0.012 15.1 0.3 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF4088 PF13317.6 KEZ35596.1 - 0.044 13.3 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) HTH_25 PF13413.6 KEZ35596.1 - 0.066 13.1 0.4 0.3 11.0 0.4 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 KEZ35597.1 - 1.5e-09 37.6 0.4 6.7e-09 35.5 0.0 2.1 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.7 KEZ35597.1 - 2e-09 37.2 1.5 4.3e-09 36.1 0.6 2.0 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 KEZ35597.1 - 0.00031 20.7 0.3 0.00031 20.7 0.3 2.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_27 PF13463.6 KEZ35597.1 - 0.0004 20.8 0.4 0.0026 18.2 0.0 2.3 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KEZ35597.1 - 0.00057 19.6 0.6 0.00057 19.6 0.6 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KEZ35597.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KEZ35597.1 - 0.031 14.3 0.0 0.093 12.7 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KEZ35597.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MFS_1 PF07690.16 KEZ35599.1 - 2.2e-48 165.0 45.0 3.5e-48 164.3 45.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 KEZ35599.1 - 2.2e-06 26.3 18.0 2.2e-06 26.3 18.0 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector TRI12 PF06609.13 KEZ35599.1 - 8.8e-05 21.1 5.3 8.8e-05 21.1 5.3 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HTH_8 PF02954.19 KEZ35600.1 - 2.9e-09 36.6 0.1 7e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_AsnC-type PF13404.6 KEZ35600.1 - 2.7e-05 23.9 0.2 0.00012 21.8 0.2 2.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain GAF PF01590.26 KEZ35600.1 - 4.7e-05 24.0 0.6 0.00015 22.4 0.1 2.0 2 0 0 2 2 1 1 GAF domain HTH_24 PF13412.6 KEZ35600.1 - 5.2e-05 22.7 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KEZ35600.1 - 0.00012 22.1 1.0 0.00055 20.0 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ35600.1 - 0.00021 21.0 0.1 0.0006 19.5 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 KEZ35600.1 - 0.0019 18.4 0.1 0.0047 17.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 KEZ35600.1 - 0.0022 17.6 0.0 0.0065 16.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 KEZ35600.1 - 0.0048 17.3 1.0 0.023 15.1 0.2 2.7 2 1 1 3 3 2 1 AAA ATPase domain HTH_7 PF02796.15 KEZ35600.1 - 0.0062 16.6 0.0 0.023 14.7 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_20 PF12840.7 KEZ35600.1 - 0.018 15.1 0.1 0.094 12.8 0.1 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KEZ35600.1 - 0.018 15.3 0.2 0.096 13.0 0.0 2.3 2 0 0 2 2 2 0 Transposase HTH_IclR PF09339.10 KEZ35600.1 - 0.018 14.8 0.1 0.061 13.1 0.1 2.0 1 0 0 1 1 1 0 IclR helix-turn-helix domain AAA_30 PF13604.6 KEZ35600.1 - 0.024 14.4 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain HTH_11 PF08279.12 KEZ35600.1 - 0.029 14.3 0.5 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 HTH domain LZ_Tnp_IS481 PF13011.6 KEZ35600.1 - 0.039 14.5 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_3 PF01381.22 KEZ35600.1 - 0.051 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix AAA_22 PF13401.6 KEZ35600.1 - 0.06 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain HTH_AraC PF00165.23 KEZ35600.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_1 PF00126.27 KEZ35600.1 - 0.081 12.9 0.4 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 KEZ35600.1 - 0.086 12.3 0.2 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 KEZ35600.1 - 0.091 12.5 0.4 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 KEZ35600.1 - 0.11 12.3 0.1 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_29 PF13551.6 KEZ35600.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.3 3 0 0 3 3 1 0 Winged helix-turn helix TetR_N PF00440.23 KEZ35600.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family RWP-RK PF02042.15 KEZ35600.1 - 0.14 12.2 0.0 0.96 9.5 0.0 2.2 2 0 0 2 2 2 0 RWP-RK domain Parvo_NS1 PF01057.17 KEZ35600.1 - 0.21 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Amidohydro_2 PF04909.14 KEZ35601.1 - 2.6e-40 139.0 2.1 2.9e-40 138.9 2.1 1.1 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 KEZ35601.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HemY_N PF07219.13 KEZ35602.1 - 0.0019 18.3 4.9 0.23 11.7 2.9 2.6 1 1 1 2 2 2 2 HemY protein N-terminus Axin_b-cat_bind PF08833.10 KEZ35602.1 - 0.09 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Axin beta-catenin binding domain DUF4493 PF14900.6 KEZ35602.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) DUF2456 PF10445.9 KEZ35604.1 - 0.015 15.4 3.5 0.021 14.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) TM2 PF05154.16 KEZ35604.1 - 0.018 15.4 19.1 0.12 12.7 19.1 2.0 1 1 0 1 1 1 0 TM2 domain PufQ PF05398.11 KEZ35604.1 - 0.44 10.7 5.0 0.71 10.0 5.0 1.3 1 0 0 1 1 1 0 PufQ cytochrome subunit TetR_C_11 PF16859.5 KEZ35605.1 - 5.4e-22 78.3 1.3 5.4e-22 78.3 1.3 2.5 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ35605.1 - 3.7e-09 36.2 0.1 8.1e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 KEZ35605.1 - 0.03 14.1 0.7 0.093 12.6 0.2 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain MFS_1 PF07690.16 KEZ35606.1 - 2.5e-15 56.3 62.0 6.7e-10 38.4 35.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ35606.1 - 2e-08 33.5 2.1 2e-08 33.5 2.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter HTH_3 PF01381.22 KEZ35607.1 - 2.6e-10 40.2 0.1 2.9e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ35607.1 - 7.8e-10 39.0 0.6 9.3e-10 38.7 0.6 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ35607.1 - 6.4e-07 29.3 0.1 7.6e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ35607.1 - 9e-05 22.3 0.3 0.00012 21.9 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ35607.1 - 0.00054 20.4 0.0 0.00074 19.9 0.0 1.2 1 1 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KEZ35607.1 - 0.0045 16.7 0.6 0.0057 16.4 0.6 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 KEZ35607.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 HTH domain Troponin PF00992.20 KEZ35607.1 - 0.035 14.4 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Troponin HTH_24 PF13412.6 KEZ35607.1 - 0.041 13.4 0.1 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KEZ35607.1 - 0.046 13.6 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 KEZ35607.1 - 0.065 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LPG_synthase_TM PF03706.13 KEZ35608.1 - 0.085 12.4 10.7 0.32 10.5 10.4 1.8 1 1 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region GHMP_kinases_N PF00288.26 KEZ35608.1 - 0.27 11.5 2.4 0.63 10.3 0.6 2.4 2 1 0 2 2 2 0 GHMP kinases N terminal domain DUF2231 PF09990.9 KEZ35608.1 - 0.36 11.3 6.7 0.23 11.9 2.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) DUF4131 PF13567.6 KEZ35608.1 - 2.3 7.8 8.8 0.18 11.5 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Acyltransferase PF01553.21 KEZ35609.1 - 9.7e-20 70.6 0.0 1.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Lar_N PF09861.9 KEZ35610.1 - 1.8e-30 105.7 0.0 2.7e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Lactate racemase N-terminal domain ADH_zinc_N PF00107.26 KEZ35611.1 - 5.6e-13 49.0 0.4 9.5e-13 48.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ35611.1 - 3.3e-07 30.2 0.1 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEZ35611.1 - 6.5e-05 24.0 0.2 0.00023 22.2 0.3 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ35611.1 - 6.7e-05 22.5 0.6 0.0013 18.3 0.6 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_4 PF07993.12 KEZ35612.1 - 9.3e-51 172.5 0.0 2.2e-50 171.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein HAD PF12710.7 KEZ35612.1 - 1.3e-24 87.6 2.2 1.3e-24 87.6 2.2 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Sterile PF03015.19 KEZ35612.1 - 2.1e-08 34.2 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KEZ35612.1 - 6.2e-07 29.1 0.1 2.2e-05 24.0 0.0 3.0 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ35612.1 - 0.00011 21.4 0.1 0.0016 17.6 0.1 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEZ35612.1 - 0.001 18.5 0.0 1 8.7 0.0 2.8 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase 5_3_exonuc_N PF02739.16 KEZ35613.1 - 7.4e-45 152.7 0.0 9.4e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KEZ35613.1 - 1.8e-17 63.7 0.0 3.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KEZ35613.1 - 0.015 15.9 0.2 0.054 14.1 0.2 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 KEZ35613.1 - 0.14 12.3 0.2 0.39 10.9 0.1 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif XPG_I_2 PF12813.7 KEZ35613.1 - 0.2 11.1 0.4 0.28 10.6 0.4 1.2 1 0 0 1 1 1 0 XPG domain containing AsnC_trans_reg PF01037.21 KEZ35614.1 - 2.5e-13 49.8 0.0 4.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 KEZ35614.1 - 2e-08 33.7 0.0 3.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KEZ35614.1 - 9.8e-08 31.7 0.1 2e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 KEZ35614.1 - 1.6e-05 24.7 0.1 3.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KEZ35614.1 - 0.00036 20.3 0.1 0.0008 19.2 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 KEZ35614.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 MarR family BAT PF15915.5 KEZ35614.1 - 0.056 13.3 0.2 0.082 12.8 0.2 1.3 1 1 0 1 1 1 0 GAF and HTH_10 associated domain HTH_20 PF12840.7 KEZ35614.1 - 0.057 13.5 0.2 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 KEZ35614.1 - 0.079 12.9 0.3 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_1 PF00126.27 KEZ35614.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family LexA_DNA_bind PF01726.16 KEZ35614.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain HTH_5 PF01022.20 KEZ35614.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 KEZ35614.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Amidohydro_3 PF07969.11 KEZ35615.1 - 2.2e-65 222.0 31.7 2.8e-65 221.6 31.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family CN_hydrolase PF00795.22 KEZ35616.1 - 4.6e-18 65.5 0.0 6.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 KEZ35616.1 - 0.13 12.1 0.0 0.13 12.1 0.0 3.3 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal Glycos_transf_2 PF00535.26 KEZ35617.1 - 6.5e-31 107.4 0.0 9.7e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ35617.1 - 8.9e-10 38.8 0.4 1.5e-09 38.1 0.4 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEZ35617.1 - 0.024 14.1 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KEZ35617.1 - 0.14 12.7 1.0 0.34 11.4 0.1 2.2 2 1 1 3 3 3 0 Glycosyl transferase family 2 RbpA PF13397.6 KEZ35618.1 - 2.6e-43 146.9 0.1 2.9e-43 146.7 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase-binding protein DUF4267 PF14087.6 KEZ35619.1 - 8e-06 25.9 6.7 1.1e-05 25.4 6.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) SelR PF01641.18 KEZ35620.1 - 4.4e-50 168.8 0.0 5e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_SprT PF17283.2 KEZ35620.1 - 0.00017 21.4 1.2 0.0012 18.7 0.6 2.4 2 1 0 2 2 2 1 SprT-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 KEZ35620.1 - 0.00099 18.6 1.8 0.14 11.7 0.0 3.0 2 1 0 2 2 2 2 TFIIB zinc-binding Yippee-Mis18 PF03226.14 KEZ35620.1 - 0.0037 17.4 0.0 0.0052 17.0 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_5 PF13719.6 KEZ35620.1 - 0.053 13.3 0.9 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KEZ35620.1 - 0.57 10.7 4.6 9.2 6.9 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Prot_ATP_ID_OB PF16450.5 KEZ35621.1 - 0.0064 16.4 0.1 0.0095 15.9 0.1 1.4 1 1 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain DUF397 PF04149.12 KEZ35622.1 - 8.3e-25 86.6 3.7 2.1e-18 66.1 1.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF397) Resolvase PF00239.21 KEZ35624.1 - 2.1e-33 115.5 1.9 3e-33 115.0 1.9 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 KEZ35624.1 - 4.3e-10 39.5 0.1 3.4e-09 36.6 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KEZ35624.1 - 3.6e-05 23.4 1.9 8.4e-05 22.3 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_22 PF13309.6 KEZ35624.1 - 6.5e-05 22.9 0.3 0.0022 18.0 0.0 2.9 3 0 0 3 3 3 1 HTH domain HTH_28 PF13518.6 KEZ35624.1 - 0.00018 21.6 1.0 0.0004 20.5 0.1 2.1 1 1 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KEZ35624.1 - 0.00078 19.4 2.0 0.011 15.7 0.1 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_36 PF13730.6 KEZ35624.1 - 0.0016 18.3 0.0 0.015 15.2 0.0 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KEZ35624.1 - 0.0042 17.0 0.1 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 HTH domain CENP-B_N PF04218.13 KEZ35624.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_10 PF04967.12 KEZ35624.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_4 PF13613.6 KEZ35624.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease YdaS_antitoxin PF15943.5 KEZ35624.1 - 0.064 13.1 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_32 PF13565.6 KEZ35624.1 - 0.068 13.8 1.8 0.093 13.4 0.4 2.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 KEZ35624.1 - 0.092 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix Collagen PF01391.18 KEZ35625.1 - 0.11 12.3 9.0 0.18 11.6 9.0 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_L37ae PF01780.19 KEZ35626.1 - 0.023 14.7 0.2 0.033 14.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family HypA PF01155.19 KEZ35626.1 - 0.14 12.2 0.2 0.18 11.8 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FlhC PF05280.11 KEZ35626.1 - 0.2 11.4 0.1 0.25 11.0 0.1 1.1 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) ThrE PF06738.12 KEZ35627.1 - 0.92 8.8 10.3 0.09 12.1 2.8 2.1 2 0 0 2 2 2 0 Putative threonine/serine exporter DUF3516 PF12029.8 KEZ35628.1 - 1.3e-203 677.2 0.0 1.7e-203 676.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) DEAD PF00270.29 KEZ35628.1 - 7.6e-12 45.3 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ35628.1 - 7.4e-07 29.5 0.1 1.3e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ35628.1 - 0.0016 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GA-like PF17573.2 KEZ35628.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 GA-like domain Methyltransf_19 PF04672.12 KEZ35629.1 - 4.7e-30 105.0 0.1 6.1e-30 104.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Resolvase PF00239.21 KEZ35630.1 - 3.4e-17 62.9 3.4 2.9e-16 59.9 0.7 2.7 2 1 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 KEZ35630.1 - 3.2e-15 56.4 0.0 1e-14 54.8 0.0 1.9 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 KEZ35630.1 - 2.2e-08 34.5 0.5 4.9e-08 33.4 0.5 1.6 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Helitron_like_N PF14214.6 KEZ35632.1 - 0.018 15.3 0.1 0.3 11.3 0.2 2.1 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus FtsK_SpoIIIE PF01580.18 KEZ35633.1 - 0.0013 18.1 0.0 0.0033 16.8 0.0 1.6 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.29 KEZ35633.1 - 0.21 12.0 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PspA_IM30 PF04012.12 KEZ35637.1 - 8.4e-30 104.0 28.5 1.1e-29 103.7 28.5 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF3510 PF12022.8 KEZ35637.1 - 0.08 13.3 2.0 0.12 12.8 0.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Tup_N PF08581.10 KEZ35637.1 - 0.73 10.2 5.1 11 6.4 0.7 3.4 3 1 0 3 3 3 0 Tup N-terminal TUTF7_u4 PF16631.5 KEZ35637.1 - 1 10.1 3.7 4.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Unstructured region 4 on terminal uridylyltransferase 7 DUF1043 PF06295.12 KEZ35637.1 - 2.8 7.9 8.4 0.43 10.6 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DnaJ_CXXCXGXG PF00684.19 KEZ35638.1 - 0.00023 21.5 0.9 0.00031 21.1 0.9 1.2 1 0 0 1 1 1 1 DnaJ central domain Ferritin PF00210.24 KEZ35639.1 - 2.5e-19 69.6 0.0 2.8e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain HTH_31 PF13560.6 KEZ35640.1 - 1.6e-10 41.2 11.4 3e-10 40.3 7.5 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ35640.1 - 3.1e-10 39.9 0.5 1.2e-09 38.1 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KEZ35640.1 - 6.1e-07 29.4 0.1 8.4e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ35640.1 - 8.4e-05 22.9 0.1 0.00012 22.4 0.1 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 KEZ35640.1 - 0.0026 17.6 1.7 0.0026 17.6 1.7 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain CinA PF02464.17 KEZ35641.1 - 7e-53 178.3 0.8 7e-53 178.3 0.8 1.8 2 0 0 2 2 2 1 Competence-damaged protein MoCF_biosynth PF00994.24 KEZ35641.1 - 1.2e-30 106.1 0.1 2.1e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 KEZ35641.1 - 5.9e-23 80.8 0.7 1.2e-22 79.8 0.3 1.8 2 0 0 2 2 2 1 Damage-inducible protein CinA KH domain CDP-OH_P_transf PF01066.21 KEZ35642.1 - 5.2e-12 46.4 1.2 5.2e-12 46.4 1.2 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4231 PF14015.6 KEZ35642.1 - 4.7 7.7 4.9 2 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) UPF0004 PF00919.20 KEZ35643.1 - 1.3e-21 76.4 0.0 3.9e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KEZ35643.1 - 1.1e-17 64.9 0.0 1.8e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TRAM_2 PF18693.1 KEZ35643.1 - 1.3e-08 34.8 1.7 3.4e-08 33.5 1.7 1.8 1 0 0 1 1 1 1 TRAM domain HTH_25 PF13413.6 KEZ35644.1 - 9.4e-19 67.0 0.0 1.4e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4115 PF13464.6 KEZ35644.1 - 2.9e-16 59.4 0.4 5e-16 58.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) HTH_31 PF13560.6 KEZ35644.1 - 2.2e-05 24.7 1.7 2.2e-05 24.7 1.7 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ35644.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain ODV-E18 PF10717.9 KEZ35644.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 FtsK_SpoIIIE PF01580.18 KEZ35645.1 - 2.2e-59 200.7 0.1 6.2e-42 143.6 0.0 2.2 1 1 1 2 2 2 2 FtsK/SpoIIIE family FtsK_alpha PF17854.1 KEZ35645.1 - 2.4e-25 88.6 0.1 4.4e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 KEZ35645.1 - 3.2e-23 81.3 0.1 7e-23 80.2 0.1 1.6 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_4TM PF13491.6 KEZ35645.1 - 1.3e-07 31.5 10.7 2.2e-07 30.8 10.7 1.3 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE TrwB_AAD_bind PF10412.9 KEZ35645.1 - 2.5e-05 23.4 0.0 7.7e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 KEZ35645.1 - 3.5e-05 22.9 0.0 0.00054 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.17 KEZ35645.1 - 0.00027 21.1 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 KEZ35645.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KEZ35645.1 - 0.0025 18.1 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KEZ35645.1 - 0.0091 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 KEZ35645.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KEZ35645.1 - 0.027 14.2 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ35645.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 KEZ35645.1 - 0.053 12.5 0.2 0.18 10.8 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KEZ35645.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 KEZ35645.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 KEZ35645.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KEZ35645.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KEZ35645.1 - 0.082 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KEZ35645.1 - 0.087 12.2 0.0 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein HTH_13 PF11972.8 KEZ35645.1 - 0.093 12.8 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 HTH DNA binding domain Adeno_IVa2 PF02456.15 KEZ35645.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 KEZ35645.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Lactamase_B PF00753.27 KEZ35646.1 - 1.4e-13 51.3 1.5 1.4e-13 51.3 1.5 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KEZ35646.1 - 4.7e-13 48.9 0.2 2e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain RNase_J_C PF17770.1 KEZ35646.1 - 1e-12 48.9 0.0 2.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain Lactamase_B_2 PF12706.7 KEZ35646.1 - 1.3e-11 44.4 1.4 2.9e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KEZ35646.1 - 0.041 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PriCT_1 PF08708.11 KEZ35646.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) DHDPS PF00701.22 KEZ35647.1 - 1.7e-78 263.2 0.0 2.1e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_2 PF04909.14 KEZ35647.1 - 0.0002 21.2 0.4 0.0015 18.4 0.1 2.3 2 1 1 3 3 3 1 Amidohydrolase Acetate_kinase PF00871.17 KEZ35648.1 - 2e-99 333.0 0.0 2e-96 323.1 0.0 2.2 2 0 0 2 2 2 2 Acetokinase family XFP_N PF09364.10 KEZ35649.1 - 5.5e-183 607.8 0.0 7.2e-183 607.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KEZ35649.1 - 4.3e-91 303.8 0.0 7e-91 303.2 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KEZ35649.1 - 5.6e-91 303.0 0.0 8.1e-91 302.5 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KEZ35649.1 - 0.033 14.0 0.1 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CENP-F_C_Rb_bdg PF10490.9 KEZ35649.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Thy1 PF02511.15 KEZ35650.1 - 8.6e-52 175.7 0.2 1.1e-51 175.4 0.2 1.0 1 0 0 1 1 1 1 Thymidylate synthase complementing protein PT PF04886.12 KEZ35650.1 - 0.044 13.3 2.2 0.068 12.7 2.2 1.3 1 0 0 1 1 1 0 PT repeat tRNA-synt_His PF13393.6 KEZ35652.1 - 3.6e-28 98.7 0.0 4.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KEZ35652.1 - 0.0036 17.4 0.0 0.0091 16.1 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain UDPG_MGDP_dh_N PF03721.14 KEZ35653.1 - 2e-51 174.2 0.0 2.4e-41 141.4 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KEZ35653.1 - 3.7e-29 100.8 0.0 7.4e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KEZ35653.1 - 7.3e-27 93.8 0.4 3.9e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 KEZ35653.1 - 0.00041 20.3 0.5 0.0019 18.1 0.0 2.4 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ35653.1 - 0.00057 19.3 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KEZ35653.1 - 0.00084 19.5 0.2 0.013 15.7 0.0 2.7 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ35653.1 - 0.012 16.2 0.6 21 5.8 0.0 3.6 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KEZ35653.1 - 0.041 13.2 0.2 0.09 12.1 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KEZ35653.1 - 0.13 12.7 1.5 19 5.7 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain Epimerase PF01370.21 KEZ35654.1 - 3.2e-57 193.7 0.0 4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ35654.1 - 5.3e-57 193.7 0.0 7.1e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ35654.1 - 2.5e-15 56.2 0.0 7.2e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEZ35654.1 - 2.1e-14 53.3 0.0 3.6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEZ35654.1 - 5.2e-14 52.1 0.0 1.6e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KEZ35654.1 - 5.5e-09 35.6 0.0 1.6e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEZ35654.1 - 6.5e-09 35.9 0.1 2.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KEZ35654.1 - 5e-08 32.6 0.0 3.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEZ35654.1 - 0.00017 21.5 0.1 0.0027 17.7 0.1 2.1 1 1 1 2 2 2 1 KR domain NmrA PF05368.13 KEZ35654.1 - 0.0069 16.0 0.1 0.017 14.7 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family COX6C PF02937.15 KEZ35655.1 - 1.2 9.3 2.9 2.5 8.3 2.9 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc GDP_Man_Dehyd PF16363.5 KEZ35657.1 - 3.9e-50 171.1 0.0 3.2e-49 168.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ35657.1 - 1.2e-45 155.8 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEZ35657.1 - 2.1e-06 27.1 0.0 0.057 12.6 0.5 2.3 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KEZ35657.1 - 2.8e-06 26.5 0.0 3.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEZ35657.1 - 6.1e-05 22.3 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEZ35657.1 - 0.0058 15.8 0.0 0.039 13.0 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KEZ35657.1 - 0.06 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase HSP70 PF00012.20 KEZ35659.1 - 0.12 10.5 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein DapB_C PF05173.14 KEZ35660.1 - 1.2e-28 99.5 0.0 1.8e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 KEZ35660.1 - 3.6e-26 91.7 0.3 1.5e-24 86.5 0.3 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 KEZ35660.1 - 0.01 16.5 0.4 0.029 15.0 0.4 1.7 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ35660.1 - 0.018 15.3 1.6 0.31 11.3 0.1 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Peptidase_M16_C PF05193.21 KEZ35661.1 - 3.6e-40 137.9 0.0 9.4e-40 136.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEZ35661.1 - 2.6e-35 121.6 0.0 3.8e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RNase_PH PF01138.21 KEZ35662.1 - 8.5e-40 136.3 0.0 1.3e-20 74.3 0.0 2.7 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 KEZ35662.1 - 1.4e-16 60.8 1.2 3e-16 59.7 1.2 1.6 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 KEZ35662.1 - 2.2e-15 56.8 0.1 4.2e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 KEZ35662.1 - 1e-10 41.3 1.0 2.7e-10 39.9 1.0 1.8 1 0 0 1 1 1 1 KH domain RNase_PH_C PF03725.15 KEZ35662.1 - 1.9e-09 37.4 0.0 0.0016 18.5 0.0 2.8 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_2 PF07650.17 KEZ35662.1 - 0.0022 17.8 0.3 0.011 15.6 0.3 2.1 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KEZ35662.1 - 0.051 13.5 0.4 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 KH domain Ribosomal_S15 PF00312.22 KEZ35663.1 - 6.5e-37 125.6 2.5 7.2e-37 125.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 FAD_syn PF06574.12 KEZ35664.1 - 7.5e-49 165.6 0.0 1.1e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 KEZ35664.1 - 6.2e-35 119.9 0.0 2.6e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 Riboflavin kinase CTP_transf_like PF01467.26 KEZ35664.1 - 0.2 11.9 0.0 0.67 10.1 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase-like TruB_N PF01509.18 KEZ35665.1 - 1.6e-43 148.6 0.0 2.1e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C PF09142.11 KEZ35665.1 - 1.1e-20 73.1 2.5 1.1e-20 73.1 2.5 2.4 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal TruB_C_2 PF16198.5 KEZ35665.1 - 2.7e-13 49.9 0.2 6.1e-13 48.7 0.2 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 KEZ35665.1 - 0.029 14.4 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain DHH PF01368.20 KEZ35666.1 - 8.2e-15 54.9 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 KEZ35666.1 - 2.8e-12 47.2 0.1 5.4e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 DHHA1 domain RBFA PF02033.18 KEZ35667.1 - 1e-25 90.2 0.0 1.3e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A DUF503 PF04456.12 KEZ35668.1 - 1.2e-32 111.5 0.2 1.5e-32 111.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF503) IF-2 PF11987.8 KEZ35669.1 - 2.6e-36 123.9 0.3 5.9e-36 122.8 0.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 KEZ35669.1 - 2.9e-33 115.0 3.6 3e-31 108.5 3.6 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEZ35669.1 - 3.3e-08 33.6 0.2 7.3e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KEZ35669.1 - 2.7e-06 27.1 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 KEZ35669.1 - 3.1e-06 27.5 3.9 0.02 15.3 0.2 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KEZ35669.1 - 0.0049 16.8 0.2 0.06 13.2 0.0 2.5 1 1 1 2 2 2 1 RsgA GTPase IF2_N PF04760.15 KEZ35669.1 - 0.0063 16.3 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 KEZ35669.1 - 0.0095 15.4 0.0 0.029 13.8 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KEZ35669.1 - 0.039 14.2 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SIS_2 PF13580.6 KEZ35669.1 - 0.054 13.5 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 SIS domain KH_5 PF13184.6 KEZ35671.1 - 3.3e-26 91.1 0.0 1.5e-25 89.0 0.0 2.0 2 0 0 2 2 2 1 NusA-like KH domain NusA_N PF08529.11 KEZ35671.1 - 8.8e-20 71.3 0.3 5.8e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 NusA N-terminal domain KH_2 PF07650.17 KEZ35671.1 - 0.00027 20.7 0.0 0.16 11.8 0.0 3.3 3 0 0 3 3 3 1 KH domain KH_1 PF00013.29 KEZ35671.1 - 0.0019 18.0 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 2 KH domain DUF150 PF02576.17 KEZ35672.1 - 2.2e-16 60.0 0.0 4.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 KEZ35672.1 - 6.1e-05 23.1 0.0 0.00017 21.6 0.0 1.8 1 1 0 1 1 1 1 RimP C-terminal SH3 domain SnoaL_2 PF12680.7 KEZ35672.1 - 0.063 13.9 0.9 0.063 13.9 0.9 1.8 2 1 0 2 2 2 0 SnoaL-like domain CarboxypepD_reg PF13620.6 KEZ35672.1 - 0.33 11.2 5.7 81 3.6 0.1 4.0 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain DUF4439 PF14530.6 KEZ35674.1 - 6.6e-18 65.7 13.8 9e-18 65.2 13.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) Rrf2 PF02082.20 KEZ35675.1 - 1.6e-25 89.3 0.2 6.4e-25 87.3 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 KEZ35675.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding BPD_transp_1 PF00528.22 KEZ35676.1 - 8.5e-15 55.0 13.5 8.5e-15 55.0 13.5 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KEZ35677.1 - 1.8e-27 96.5 0.0 2.8e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ35677.1 - 8.7e-05 22.5 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ35677.1 - 0.00056 20.3 0.1 0.00093 19.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KEZ35677.1 - 0.00091 18.9 2.0 0.04 13.5 2.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEZ35677.1 - 0.00096 19.4 0.7 0.084 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KEZ35677.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KEZ35677.1 - 0.0063 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KEZ35677.1 - 0.014 15.4 0.7 0.26 11.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 KEZ35677.1 - 0.032 13.7 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEZ35677.1 - 0.077 12.7 0.1 5 6.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KEZ35677.1 - 0.13 12.1 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 NACHT domain NMT1_2 PF13379.6 KEZ35678.1 - 1.1e-25 90.8 0.1 1.8e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KEZ35678.1 - 3.4e-12 46.8 0.1 4.9e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KEZ35678.1 - 3.1e-06 27.0 0.2 6.4e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lipoprotein_9 PF03180.14 KEZ35678.1 - 0.00036 19.7 0.0 0.00063 18.9 0.0 1.3 1 1 0 1 1 1 1 NLPA lipoprotein DUF4081 PF13312.6 KEZ35679.1 - 1.6e-43 147.1 0.9 2.9e-43 146.3 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4081) Acetyltransf_1 PF00583.25 KEZ35679.1 - 4.4e-09 36.6 0.1 7.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEZ35679.1 - 5.9e-06 26.2 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KEZ35679.1 - 5.8e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ35679.1 - 0.00059 20.2 0.1 0.0015 18.9 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ35679.1 - 0.0021 18.7 0.0 0.0039 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEZ35679.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GcpE PF04551.14 KEZ35680.1 - 1.3e-133 445.4 0.2 1.5e-133 445.2 0.2 1.0 1 0 0 1 1 1 1 GcpE protein MR_MLE_C PF13378.6 KEZ35680.1 - 0.046 13.3 0.2 0.17 11.4 0.1 1.8 1 1 1 2 2 2 0 Enolase C-terminal domain-like Aldolase PF01081.19 KEZ35680.1 - 0.048 13.1 0.8 0.11 11.9 0.8 1.6 1 0 0 1 1 1 0 KDPG and KHG aldolase zf-RING_7 PF02591.15 KEZ35680.1 - 0.095 12.9 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain DUF35_N PF12172.8 KEZ35680.1 - 0.14 12.0 1.1 1 9.3 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Peptidase_M50 PF02163.22 KEZ35681.1 - 1e-45 156.0 0.0 1.4e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 KEZ35681.1 - 3.1e-10 39.7 0.0 6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KEZ35681.1 - 1.3e-07 31.8 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEZ35681.1 - 5.8e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF3679 PF12438.8 KEZ35681.1 - 0.031 14.0 0.0 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) DXP_redisom_C PF08436.12 KEZ35682.1 - 1e-37 128.1 0.0 2.2e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXPR_C PF13288.6 KEZ35682.1 - 7.6e-37 126.1 0.0 1.3e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 KEZ35682.1 - 9.8e-37 126.5 0.2 1.6e-36 125.9 0.2 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Esterase_phd PF10503.9 KEZ35683.1 - 8.1e-10 38.6 0.8 1.9e-09 37.3 0.8 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KEZ35683.1 - 0.00027 20.8 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Radical_SAM PF04055.21 KEZ35684.1 - 7.7e-17 62.2 0.0 1.7e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KEZ35684.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain CTP_transf_1 PF01148.20 KEZ35685.1 - 1.7e-51 175.6 11.1 1.9e-51 175.4 11.1 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Phage_holin_5_2 PF16079.5 KEZ35685.1 - 7.4 7.0 9.6 0.68 10.3 2.0 2.8 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V RRF PF01765.19 KEZ35686.1 - 2.7e-50 170.5 0.0 3.6e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.13 KEZ35686.1 - 0.031 14.9 2.7 0.031 14.9 2.7 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) EF_TS PF00889.19 KEZ35687.1 - 9.9e-37 126.6 1.3 2.2e-35 122.2 1.3 2.9 1 1 0 1 1 1 1 Elongation factor TS SRI PF08236.11 KEZ35687.1 - 0.0084 16.3 0.0 0.11 12.6 0.0 2.5 1 1 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain POTRA_2 PF08479.11 KEZ35687.1 - 0.12 12.2 0.1 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 POTRA domain, ShlB-type Ribosomal_S2 PF00318.20 KEZ35688.1 - 3.5e-96 320.6 0.0 4e-96 320.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Phage_integrase PF00589.22 KEZ35690.1 - 1.3e-38 132.5 0.0 2.3e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ35690.1 - 7.3e-13 48.6 1.3 7.9e-12 45.3 0.5 2.6 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain DNA_processg_A PF02481.15 KEZ35691.1 - 1.1e-66 224.1 0.0 1.6e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A LDcluster4 PF18306.1 KEZ35691.1 - 1.6e-05 24.6 5.1 0.00017 21.2 5.3 2.4 1 1 1 2 2 2 1 SLOG cluster4 family DprA_WH PF17782.1 KEZ35691.1 - 4.8e-05 23.4 2.1 0.00017 21.6 2.1 2.0 1 0 0 1 1 1 1 DprA winged helix domain Rrf2 PF02082.20 KEZ35691.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_IclR PF09339.10 KEZ35691.1 - 0.18 11.7 1.3 0.96 9.3 0.3 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Mg_chelatase PF01078.21 KEZ35692.1 - 4.9e-34 117.5 0.0 7.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 KEZ35692.1 - 2.4e-21 76.1 0.1 9e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 KEZ35692.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Y1_Tnp PF01797.16 KEZ35693.1 - 1.7e-23 83.0 0.0 2e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Transposase IS200 like Pirin PF02678.16 KEZ35694.1 - 7e-32 109.6 2.2 7e-32 109.6 2.2 1.8 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 KEZ35694.1 - 1.2e-05 25.4 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KEZ35694.1 - 0.0028 17.3 1.4 2.5 7.9 0.3 2.7 2 0 0 2 2 2 2 Cupin domain HicB PF05534.12 KEZ35695.1 - 2.2e-05 24.2 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 HicB family RHH_7 PF16777.5 KEZ35695.1 - 0.0032 17.8 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG Arc PF03869.14 KEZ35695.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF1778 PF08681.11 KEZ35695.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) RHH_4 PF13467.6 KEZ35695.1 - 0.079 12.8 0.4 0.24 11.3 0.2 1.8 1 1 1 2 2 2 0 Ribbon-helix-helix domain CopG_antitoxin PF12441.8 KEZ35695.1 - 0.12 12.9 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system PemK_toxin PF02452.17 KEZ35696.1 - 0.0012 19.2 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system DEAD PF00270.29 KEZ35697.1 - 2.2e-23 82.9 0.0 3.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ35697.1 - 1.9e-18 66.8 0.1 3.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2791 PF10923.8 KEZ35698.1 - 1.8e-137 458.6 0.0 2.1e-137 458.4 0.0 1.0 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA_16 PF13191.6 KEZ35698.1 - 7e-07 29.8 5.7 1.4e-05 25.5 5.5 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ35698.1 - 2.7e-06 27.7 0.0 0.046 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KEZ35698.1 - 0.0043 17.5 0.0 0.89 10.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEZ35698.1 - 0.038 13.9 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KEZ35698.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GGDEF_2 PF17853.1 KEZ35698.1 - 0.086 13.1 4.3 0.27 11.5 1.6 2.7 2 0 0 2 2 2 0 GGDEF-like domain TniB PF05621.11 KEZ35698.1 - 0.19 11.1 0.0 0.53 9.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein PglZ PF08665.12 KEZ35699.1 - 8.5e-13 48.8 0.0 2.6e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 PglZ domain DUF2791 PF10923.8 KEZ35700.1 - 0.0072 15.2 0.3 1 8.1 0.0 2.3 2 0 0 2 2 2 2 P-loop Domain of unknown function (DUF2791) DUF2563 PF10817.8 KEZ35700.1 - 0.043 14.4 0.2 0.16 12.6 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) T7SS_ESX_EspC PF10824.8 KEZ35700.1 - 0.78 10.2 3.4 1.6 9.3 0.3 3.0 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Methyltransf_31 PF13847.6 KEZ35701.1 - 0.00097 18.9 0.0 0.016 15.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 KEZ35701.1 - 0.0011 18.3 0.0 0.016 14.4 0.0 2.1 1 1 0 1 1 1 1 N-6 DNA Methylase TaqI_C PF12950.7 KEZ35701.1 - 0.0077 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain UPF0020 PF01170.18 KEZ35701.1 - 0.028 14.1 0.0 0.71 9.5 0.0 2.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Eco57I PF07669.11 KEZ35701.1 - 0.048 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Pkinase PF00069.25 KEZ35702.1 - 1.7e-25 89.9 0.0 3.2e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain NERD PF08378.11 KEZ35702.1 - 4.3e-17 62.5 0.0 9.9e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Nuclease-related domain Pkinase_Tyr PF07714.17 KEZ35702.1 - 7.1e-11 41.9 0.0 9.3e-05 21.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase HTH_23 PF13384.6 KEZ35702.1 - 0.03 14.1 0.1 0.18 11.7 0.1 2.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 KEZ35702.1 - 0.057 13.5 0.4 0.28 11.2 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Kdo PF06293.14 KEZ35702.1 - 0.069 12.5 0.0 3 7.1 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDT PF00800.18 KEZ35703.1 - 4.3e-56 189.6 0.0 5.3e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Ala_racemase_N PF01168.20 KEZ35703.1 - 0.029 14.0 0.5 0.091 12.4 0.0 1.9 2 1 0 2 2 2 0 Alanine racemase, N-terminal domain ACT PF01842.25 KEZ35703.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain ATP-grasp_5 PF13549.6 KEZ35704.1 - 5.2e-41 140.5 0.0 8.6e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KEZ35704.1 - 4.4e-36 123.7 1.4 2.5e-34 118.0 0.0 3.5 3 1 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KEZ35704.1 - 8.7e-22 77.8 0.6 8.7e-22 77.8 0.6 2.2 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 KEZ35704.1 - 7e-10 39.5 0.2 2.3e-09 37.8 0.2 1.9 1 0 0 1 1 1 1 CoA binding domain NAD_Gly3P_dh_N PF01210.23 KEZ35704.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 KEZ35704.1 - 0.11 13.3 0.3 0.57 11.0 0.1 2.3 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 KEZ35704.1 - 0.12 12.7 0.3 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Catalase PF00199.19 KEZ35705.1 - 4e-179 595.6 0.0 5.1e-179 595.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KEZ35705.1 - 2.7e-24 85.1 0.0 6.7e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KEZ35705.1 - 4.1e-19 68.7 0.9 6.6e-19 68.0 0.9 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KEZ35705.1 - 1.5e-11 44.4 0.5 3e-11 43.4 0.3 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family PNTB PF02233.16 KEZ35706.1 - 7e-165 549.4 36.7 8e-165 549.2 36.7 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 KEZ35706.1 - 0.00062 19.5 0.5 0.007 16.1 0.5 2.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain YL1_C PF08265.11 KEZ35706.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PNTB_4TM PF12769.7 KEZ35707.1 - 2.8e-31 107.8 6.8 3.4e-31 107.5 6.8 1.1 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch AlaDh_PNT_C PF01262.21 KEZ35708.1 - 7e-62 208.5 6.9 1.1e-61 207.9 6.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KEZ35708.1 - 9e-38 129.6 0.0 1.9e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 KEZ35708.1 - 0.00095 18.6 0.0 0.83 9.0 0.1 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 KEZ35709.1 - 1.5e-31 108.5 0.4 2.4e-31 107.8 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ35709.1 - 8.7e-29 100.1 0.5 1.6e-28 99.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ35709.1 - 3.4e-07 31.4 0.1 5.3e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ35709.1 - 0.0054 16.0 2.6 0.011 15.0 2.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.22 KEZ35710.1 - 7.9e-162 538.9 0.0 8.9e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KEZ35710.1 - 0.13 12.3 1.1 0.29 11.2 1.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Herpes_capsid PF06112.11 KEZ35711.1 - 2.6 8.1 8.6 4.8 7.2 8.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ADP_ribosyl_GH PF03747.14 KEZ35712.1 - 2.6e-63 214.5 15.3 2.6e-63 214.5 15.3 2.1 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase DUF262 PF03235.14 KEZ35712.1 - 1.5e-32 113.6 0.0 3.2e-32 112.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF1524 PF07510.11 KEZ35712.1 - 5.4e-27 94.4 0.0 8.1e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) DNA_binding_1 PF01035.20 KEZ35712.1 - 1.9e-07 31.1 0.0 5.3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rick_17kDa_Anti PF05433.15 KEZ35712.1 - 0.28 11.1 5.8 3.5 7.6 0.3 3.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KEZ35712.1 - 0.6 10.1 13.6 0.78 9.8 0.0 3.5 3 0 0 3 3 3 0 Glycine zipper TrkA_N PF02254.18 KEZ35713.1 - 2.6e-32 111.5 6.1 2.7e-19 69.6 0.4 2.8 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 KEZ35713.1 - 5.9e-10 38.8 2.0 0.0068 16.2 0.0 4.7 4 0 0 4 4 4 3 TrkA-C domain Ion_trans_2 PF07885.16 KEZ35713.1 - 1.5e-07 31.3 6.1 3.6e-07 30.0 6.1 1.7 1 0 0 1 1 1 1 Ion channel XdhC_C PF13478.6 KEZ35713.1 - 8.8e-06 26.2 2.6 0.0082 16.6 0.2 2.4 2 0 0 2 2 2 2 XdhC Rossmann domain NAD_binding_7 PF13241.6 KEZ35713.1 - 0.0011 19.4 4.3 0.11 13.0 0.3 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding F420_oxidored PF03807.17 KEZ35713.1 - 0.034 14.7 0.8 0.18 12.4 0.1 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ion_trans PF00520.31 KEZ35713.1 - 0.17 11.1 1.6 0.26 10.5 1.6 1.2 1 0 0 1 1 1 0 Ion transport protein DUF1772 PF08592.11 KEZ35714.1 - 1.9e-13 50.9 8.1 1.9e-13 50.9 8.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) COX4_pro_2 PF07835.12 KEZ35714.1 - 0.89 9.7 0.0 0.89 9.7 0.0 3.1 3 1 1 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV TetR_N PF00440.23 KEZ35715.1 - 1.7e-07 30.9 1.5 6.7e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 KEZ35715.1 - 0.0024 17.6 1.5 0.016 15.0 0.0 2.8 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KEZ35715.1 - 0.0031 17.3 0.2 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KEZ35715.1 - 0.02 15.0 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 KEZ35715.1 - 0.021 14.2 0.1 0.1 12.1 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.21 KEZ35715.1 - 0.033 14.0 0.4 0.57 10.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_AsnC-type PF13404.6 KEZ35715.1 - 0.049 13.5 1.1 0.22 11.4 0.2 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Flg_hook PF02120.16 KEZ35715.1 - 0.19 11.6 1.5 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK HTH_20 PF12840.7 KEZ35715.1 - 0.22 11.6 0.3 0.22 11.6 0.3 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain Dimerisation2 PF16864.5 KEZ35715.1 - 0.27 11.3 1.6 12 5.9 0.0 3.1 2 2 2 4 4 4 0 Dimerisation domain MarR_2 PF12802.7 KEZ35715.1 - 0.57 10.1 5.1 3.2 7.7 0.2 3.3 2 1 0 2 2 2 0 MarR family Hydrolase_4 PF12146.8 KEZ35716.1 - 2.4e-12 46.6 0.1 1.8e-11 43.7 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ35716.1 - 2.3e-07 30.8 0.0 1.3e-05 25.0 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ35716.1 - 5.4e-07 30.4 14.8 7.1e-07 30.1 14.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KEZ35716.1 - 0.0063 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 KEZ35716.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KEZ35716.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 KEZ35716.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF4442 PF14539.6 KEZ35717.1 - 1.7e-14 54.1 0.0 2.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT PF03061.22 KEZ35717.1 - 0.017 15.5 1.1 0.024 15.0 0.3 1.6 2 0 0 2 2 2 0 Thioesterase superfamily YiiD_C PF09500.10 KEZ35717.1 - 0.067 13.0 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) FAD_binding_3 PF01494.19 KEZ35718.1 - 6.9e-16 58.4 0.8 2.2e-15 56.8 0.8 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ35718.1 - 4.4e-06 26.5 0.7 0.045 13.3 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ35718.1 - 0.00043 19.5 0.4 0.21 10.6 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KEZ35718.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ35718.1 - 0.014 14.8 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ35718.1 - 0.014 14.7 0.1 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ35718.1 - 0.028 13.5 0.0 6.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ35718.1 - 0.042 14.1 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEZ35718.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lipase_GDSL_2 PF13472.6 KEZ35719.1 - 3.5e-25 89.4 2.3 4.3e-25 89.1 2.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ35719.1 - 1e-07 32.1 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KEZ35719.1 - 0.089 12.5 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX ketoacyl-synt PF00109.26 KEZ35720.1 - 4.2e-60 203.4 0.7 1.2e-59 202.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ35720.1 - 3.9e-36 123.6 0.4 1.5e-35 121.7 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEZ35720.1 - 2e-34 119.5 0.2 5.6e-34 118.1 0.2 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEZ35720.1 - 5.8e-31 107.8 3.8 3.9e-30 105.1 3.8 2.3 1 1 0 1 1 1 1 KR domain PS-DH PF14765.6 KEZ35720.1 - 7.6e-24 84.5 0.1 7.6e-24 84.5 0.1 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 KEZ35720.1 - 2.8e-05 24.4 0.0 8.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KEZ35720.1 - 4.7e-05 23.8 0.0 9.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEZ35720.1 - 0.00064 19.2 0.5 0.034 13.6 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase FabA PF07977.13 KEZ35721.1 - 9.9e-36 122.4 0.0 4.9e-32 110.4 0.0 3.2 3 1 0 3 3 3 2 FabA-like domain NMO PF03060.15 KEZ35722.1 - 7.7e-09 35.4 3.9 1e-07 31.7 3.9 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase PfaD_N PF18328.1 KEZ35722.1 - 0.0059 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit PfaD N-terminal domain FMN_dh PF01070.18 KEZ35722.1 - 0.038 13.0 1.4 0.091 11.8 1.4 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEZ35722.1 - 0.071 12.2 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Conserved region in glutamate synthase IMPDH PF00478.25 KEZ35722.1 - 0.11 11.4 0.5 0.24 10.3 0.5 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Carboxyl_trans PF01039.22 KEZ35723.1 - 3.1e-38 131.6 2.2 3e-21 75.6 0.1 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain ACCA PF03255.14 KEZ35723.1 - 6.8e-33 113.6 0.1 4.3e-32 111.0 0.0 2.1 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit zf-ACC PF17848.1 KEZ35723.1 - 0.0004 20.4 0.3 0.00071 19.6 0.3 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain ECH_1 PF00378.20 KEZ35723.1 - 0.00096 18.5 4.6 0.0079 15.5 0.7 3.2 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_N PF02771.16 KEZ35723.1 - 0.079 13.6 2.9 0.87 10.3 0.1 3.2 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain Biotin_lipoyl PF00364.22 KEZ35724.1 - 1.5e-18 66.3 0.9 3e-18 65.4 0.0 2.0 3 0 0 3 3 3 1 Biotin-requiring enzyme RnfC_N PF13375.6 KEZ35724.1 - 5e-05 23.2 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 KEZ35724.1 - 9.2e-05 22.2 0.7 1.3 9.0 0.0 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like GCV_H PF01597.19 KEZ35724.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein CPSase_L_D2 PF02786.17 KEZ35725.1 - 3.3e-73 245.7 0.0 4.7e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEZ35725.1 - 5.7e-45 152.4 0.0 2.4e-44 150.4 0.0 2.1 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ35725.1 - 1.4e-35 121.7 0.0 2.6e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 KEZ35725.1 - 1.7e-08 34.3 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ35725.1 - 3.8e-06 26.6 0.0 8.1e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KEZ35725.1 - 0.0018 18.4 0.0 0.0047 17.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KEZ35725.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAL_C2 PF18603.1 KEZ35725.1 - 0.0077 16.4 0.0 0.032 14.4 0.0 2.2 1 1 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 KEZ35725.1 - 0.053 12.8 0.0 0.099 11.9 0.0 1.4 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KEZ35725.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain HpcH_HpaI PF03328.14 KEZ35726.1 - 2.1e-28 99.0 8.9 1.1e-27 96.7 5.1 2.5 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEZ35726.1 - 2.2e-12 46.8 0.0 6.7e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold MaoC_dehydratas PF01575.19 KEZ35727.1 - 1.1e-24 86.3 0.1 1.5e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KEZ35727.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Metallophos PF00149.28 KEZ35728.1 - 1.5e-05 25.6 0.0 2.3e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FdhD-NarQ PF02634.15 KEZ35729.1 - 2.5e-18 66.7 0.5 2.8e-18 66.5 0.5 1.0 1 0 0 1 1 1 1 FdhD/NarQ family OrfB_Zn_ribbon PF07282.11 KEZ35730.1 - 2.9e-23 81.6 0.1 3.7e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain C1_2 PF03107.16 KEZ35730.1 - 0.018 15.3 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 C1 domain DZR PF12773.7 KEZ35730.1 - 0.031 14.3 0.2 0.05 13.6 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF5596 PF18082.1 KEZ35730.1 - 0.095 12.5 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Zn_Tnp_IS1595 PF12760.7 KEZ35730.1 - 0.31 11.1 4.4 0.57 10.2 4.4 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KEZ35730.1 - 0.33 10.5 4.7 1.3 8.6 4.7 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Resolvase PF00239.21 KEZ35731.1 - 0.00017 21.7 0.1 0.0002 21.5 0.1 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain DUF374 PF04028.13 KEZ35731.1 - 0.057 13.0 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Methyltransf_19 PF04672.12 KEZ35733.1 - 3.1e-41 141.7 0.0 3.6e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase FxsA PF04186.13 KEZ35735.1 - 0.17 12.0 3.9 0.23 11.6 1.2 2.2 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Acetyltransf_3 PF13302.7 KEZ35736.1 - 2.5e-18 67.1 0.1 3.4e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ35736.1 - 5.1e-09 36.4 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KEZ35736.1 - 1.9e-07 31.3 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEZ35736.1 - 4.5e-05 23.2 0.3 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ35736.1 - 0.033 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein MoCF_biosynth PF00994.24 KEZ35737.1 - 7.9e-35 119.6 1.0 1e-34 119.3 1.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain PikAIV_N PF18605.1 KEZ35737.1 - 0.42 10.2 2.0 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain MoaC PF01967.21 KEZ35738.1 - 9.8e-49 164.9 3.2 1.1e-48 164.7 3.2 1.0 1 0 0 1 1 1 1 MoaC family Hjc PF01870.18 KEZ35738.1 - 0.092 12.7 0.2 0.56 10.2 0.0 2.0 1 1 1 2 2 2 0 Archaeal holliday junction resolvase (hjc) MoeA_N PF03453.17 KEZ35739.1 - 4e-46 156.6 4.4 4e-46 156.6 4.4 2.6 3 0 0 3 3 3 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KEZ35739.1 - 7.8e-29 100.2 0.2 2.9e-28 98.4 0.2 1.9 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KEZ35739.1 - 1.8e-10 40.8 0.3 6.6e-10 39.0 0.1 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) T4BSS_DotH_IcmK PF12293.8 KEZ35739.1 - 0.099 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion NTP_transferase PF00483.23 KEZ35740.1 - 5.1e-23 81.9 0.0 6.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ35740.1 - 6.5e-10 39.6 1.7 1.1e-09 38.9 1.7 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glycos_transf_2 PF00535.26 KEZ35740.1 - 0.046 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 5-FTHF_cyc-lig PF01812.20 KEZ35741.1 - 6.1e-35 120.8 0.0 7.3e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Trns_repr_metal PF02583.17 KEZ35746.1 - 2.2e-31 108.1 0.6 2.4e-31 107.9 0.6 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor 2OG-FeII_Oxy_2 PF13532.6 KEZ35747.1 - 2.7e-08 34.3 0.0 1.6e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KEZ35748.1 - 6.9e-18 65.0 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KEZ35748.1 - 4.2e-17 62.2 0.9 1.9e-06 28.5 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KEZ35748.1 - 3.9e-12 46.0 0.0 5.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PD40 PF07676.12 KEZ35748.1 - 7.5e-07 28.9 0.2 0.29 11.1 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KEZ35748.1 - 2.1e-06 28.0 0.0 11 6.4 0.1 4.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ35748.1 - 0.0006 18.9 0.0 0.29 10.1 0.0 3.7 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KEZ35748.1 - 0.12 11.4 0.2 1.9 7.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) T2SSM PF04612.12 KEZ35748.1 - 0.14 12.2 1.0 0.32 11.1 1.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Nbas_N PF15492.6 KEZ35748.1 - 0.22 10.8 0.1 16 4.7 0.0 2.8 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF1180 PF06679.12 KEZ35748.1 - 0.42 11.0 6.8 1.4 9.3 6.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Robl_LC7 PF03259.17 KEZ35748.1 - 1.6 8.6 4.4 42 4.0 0.2 3.9 5 0 0 5 5 5 0 Roadblock/LC7 domain Response_reg PF00072.24 KEZ35749.1 - 2.6e-25 88.8 0.0 4.6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 KEZ35749.1 - 0.062 13.7 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 KEZ35750.1 - 1.8e-26 92.8 0.0 3.8e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ35750.1 - 6.3e-25 87.5 0.8 1.1e-24 86.8 0.3 1.7 2 0 0 2 2 1 1 Response regulator receiver domain GAF_2 PF13185.6 KEZ35750.1 - 1.1e-16 61.4 0.1 3.8e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KEZ35750.1 - 1.3e-16 60.3 0.5 1.3e-16 60.3 0.5 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ35750.1 - 2.5e-12 47.0 1.6 3.9e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 HAMP domain GAF PF01590.26 KEZ35750.1 - 1.3e-08 35.5 0.0 2.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain OmpH PF03938.14 KEZ35750.1 - 0.026 14.9 7.1 0.044 14.1 3.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PMC2NT PF08066.12 KEZ35750.1 - 0.079 13.7 1.0 1.5 9.6 0.0 3.3 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Laminin_II PF06009.12 KEZ35750.1 - 0.14 12.1 14.9 3.5 7.6 1.0 3.4 2 1 0 3 3 3 0 Laminin Domain II DUF3552 PF12072.8 KEZ35750.1 - 0.39 10.1 10.6 0.11 12.0 7.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Atg14 PF10186.9 KEZ35750.1 - 1.2 8.1 7.2 0.19 10.8 3.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 H-kinase_dim PF02895.14 KEZ35750.1 - 1.5 9.2 10.6 0.68 10.4 3.7 3.4 4 0 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain DUF4200 PF13863.6 KEZ35750.1 - 4.8 7.6 11.9 16 5.9 8.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Fmp27_WPPW PF10359.9 KEZ35750.1 - 7.4 5.3 6.4 1.9 7.3 3.3 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ZapB PF06005.12 KEZ35750.1 - 7.6 7.0 14.7 44 4.6 10.8 3.5 3 1 0 3 3 3 0 Cell division protein ZapB HAMP PF00672.25 KEZ35751.1 - 1.6e-19 70.0 4.0 1.3e-11 44.7 1.2 3.0 3 1 1 4 4 4 2 HAMP domain Laminin_II PF06009.12 KEZ35751.1 - 7.9e-05 22.7 0.2 0.15 12.1 0.0 2.1 2 0 0 2 2 2 2 Laminin Domain II DUF948 PF06103.11 KEZ35751.1 - 0.00027 21.1 4.6 0.068 13.4 2.1 3.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KEZ35751.1 - 0.0026 17.8 0.5 0.016 15.2 0.5 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Anillin_N PF16018.5 KEZ35751.1 - 0.013 16.0 0.1 0.29 11.8 0.0 2.1 2 0 0 2 2 2 0 Anillin N-terminus UPF0184 PF03670.13 KEZ35751.1 - 0.014 15.8 0.0 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Apolipoprotein PF01442.18 KEZ35751.1 - 0.026 14.4 0.9 2.2 8.1 0.1 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain COG2 PF06148.11 KEZ35751.1 - 0.027 14.6 0.7 4.4 7.4 0.1 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG17 PF04108.12 KEZ35751.1 - 0.05 12.7 0.0 0.061 12.4 0.0 1.3 1 1 0 1 1 1 0 Autophagy protein Apg17 WXG100 PF06013.12 KEZ35751.1 - 0.058 13.6 0.5 11 6.3 0.0 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DASH_Dad2 PF08654.10 KEZ35751.1 - 0.062 13.7 2.0 0.94 9.9 0.7 2.7 1 1 0 2 2 2 0 DASH complex subunit Dad2 DUF5082 PF16888.5 KEZ35751.1 - 0.07 13.4 0.0 0.14 12.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1759 PF03564.15 KEZ35751.1 - 0.077 12.9 0.1 2.1 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) DUF3829 PF12889.7 KEZ35751.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) FlaC_arch PF05377.11 KEZ35751.1 - 0.14 12.6 0.1 4.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HAMP PF00672.25 KEZ35752.1 - 3.3e-06 27.4 2.7 1.1e-05 25.6 0.1 3.1 3 1 1 4 4 4 1 HAMP domain YjgF_endoribonc PF14588.6 KEZ35752.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease SpoIIE PF07228.12 KEZ35753.1 - 1.1e-37 129.9 1.9 5.7e-36 124.2 1.0 3.1 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) GAF_3 PF13492.6 KEZ35753.1 - 1.7e-10 41.3 1.0 5.8e-10 39.6 1.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 KEZ35753.1 - 2.3e-09 37.3 0.0 4.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_2 PF13185.6 KEZ35753.1 - 3.9e-05 24.0 2.2 0.00018 21.8 1.1 2.8 2 1 0 2 2 2 1 GAF domain GAF PF01590.26 KEZ35753.1 - 0.003 18.2 0.2 0.0097 16.5 0.2 1.9 1 0 0 1 1 1 1 GAF domain CAP_N PF01213.19 KEZ35753.1 - 0.099 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HATPase_c PF02518.26 KEZ35753.1 - 0.13 12.8 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KEZ35754.1 - 2.3e-08 34.0 0.0 5.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Orn_Arg_deC_N PF02784.16 KEZ35756.1 - 2.1e-26 92.8 0.0 9.3e-24 84.1 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KEZ35756.1 - 2.1e-15 56.7 0.0 2.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KEZ35756.1 - 2.3e-05 24.1 0.3 0.0012 18.5 0.1 2.5 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain Aminotran_3 PF00202.21 KEZ35757.1 - 1.7e-91 306.9 0.0 1.9e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Dpy-30 PF05186.13 KEZ35757.1 - 0.045 13.4 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Dpy-30 motif Pyridoxal_deC PF00282.19 KEZ35758.1 - 7.8e-41 140.0 0.0 3.1e-33 115.0 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain IucA_IucC PF04183.12 KEZ35759.1 - 7e-66 222.2 0.0 9.5e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 KEZ35759.1 - 1.8e-30 106.5 0.1 3.5e-30 105.6 0.1 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter K_oxygenase PF13434.6 KEZ35760.1 - 3.6e-110 368.3 0.0 4.4e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ35760.1 - 6.2e-07 28.9 0.0 0.0051 16.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase IucA_IucC PF04183.12 KEZ35761.1 - 2.1e-81 273.0 0.0 2.8e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 KEZ35761.1 - 2.4e-33 115.9 0.9 4.5e-33 115.0 0.9 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Gln-synt_C PF00120.24 KEZ35762.1 - 3.7e-87 292.6 0.0 1.2e-48 165.9 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KEZ35762.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain MMPL PF03176.15 KEZ35763.1 - 7.8e-66 222.3 42.8 2.8e-38 131.7 18.6 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KEZ35763.1 - 8.7 6.2 12.4 0.32 10.8 2.9 2.4 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation TetR_C_33 PF13305.6 KEZ35764.1 - 9.7e-22 77.7 1.3 9.7e-22 77.7 1.3 2.5 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ35764.1 - 3.5e-07 29.9 0.1 7.7e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_28 PF17937.1 KEZ35764.1 - 4 8.0 10.8 0.075 13.5 0.8 2.8 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Glycos_transf_2 PF00535.26 KEZ35765.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 2 GGDEF PF00990.21 KEZ35766.1 - 6.6e-38 130.0 0.0 2.3e-30 105.5 0.0 2.3 2 0 0 2 2 2 2 Diguanylate cyclase, GGDEF domain Methyltransf_21 PF05050.12 KEZ35767.1 - 6.9e-17 62.0 0.0 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 KEZ35767.1 - 0.0079 15.5 0.0 0.036 13.4 0.0 1.8 1 1 0 1 1 1 1 Vibrio cholerae RfbT protein GDC-P PF02347.16 KEZ35768.1 - 4.2e-174 579.4 0.0 1.7e-163 544.4 0.0 2.1 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KEZ35768.1 - 0.00011 21.4 0.1 0.00042 19.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ35768.1 - 0.01 15.2 0.5 0.076 12.3 0.1 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase HTH_17 PF12728.7 KEZ35770.1 - 0.002 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PIG-L PF02585.17 KEZ35771.1 - 2.6e-20 73.4 0.6 6.2e-20 72.2 0.2 1.7 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Pkinase PF00069.25 KEZ35772.1 - 0.0037 16.7 0.0 0.0038 16.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain AAA_3 PF07726.11 KEZ35773.1 - 5.5e-59 197.7 0.0 1.9e-58 196.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KEZ35773.1 - 2.8e-18 65.5 2.9 2.8e-18 65.5 2.9 2.7 2 1 1 3 3 3 1 AAA lid domain AAA_5 PF07728.14 KEZ35773.1 - 1.4e-11 44.6 0.0 2.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEZ35773.1 - 0.0018 18.0 0.0 0.0072 16.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KEZ35773.1 - 0.0034 17.8 0.0 0.094 13.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KEZ35773.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 KEZ35773.1 - 0.094 12.1 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ35773.1 - 0.21 11.3 0.0 1.2 8.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF883 PF05957.13 KEZ35775.1 - 0.053 14.1 0.2 0.083 13.5 0.2 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GLE1 PF07817.13 KEZ35775.1 - 0.094 11.9 0.3 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 GLE1-like protein HECW1_helix PF18436.1 KEZ35775.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 HopW1-1 PF15457.6 KEZ35775.1 - 0.13 11.5 0.4 0.14 11.4 0.4 1.0 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Pre-PUA PF17832.1 KEZ35775.1 - 0.17 12.6 0.3 0.21 12.3 0.3 1.1 1 0 0 1 1 1 0 Pre-PUA-like domain CDPS PF16715.5 KEZ35776.1 - 0.11 12.1 0.7 0.14 11.8 0.7 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase FUSC_2 PF13515.6 KEZ35777.1 - 1.1e-12 48.1 13.2 1.1e-12 48.1 13.2 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 KEZ35777.1 - 4.2e-08 32.2 14.9 4.2e-08 32.2 14.9 4.1 3 1 1 4 4 4 1 Fusaric acid resistance protein family DUF2651 PF10852.8 KEZ35777.1 - 0.56 10.9 16.1 0.61 10.7 5.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) FUSC-like PF12805.7 KEZ35777.1 - 8.8 5.3 12.3 16 4.4 12.3 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Methyltransf_19 PF04672.12 KEZ35780.1 - 6.5e-98 327.5 0.1 7.3e-98 327.3 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase MMPL PF03176.15 KEZ35781.1 - 1.1e-45 156.1 43.8 1.8e-28 99.4 25.9 2.3 2 0 0 2 2 2 2 MMPL family HSP33 PF01430.19 KEZ35781.1 - 0.68 9.3 1.5 3.3 7.1 1.9 1.8 2 0 0 2 2 2 0 Hsp33 protein PAP2_C PF14360.6 KEZ35781.1 - 9.3 6.9 7.6 0.47 11.0 0.1 2.7 3 0 0 3 3 3 0 PAP2 superfamily C-terminal EpuA PF11772.8 KEZ35782.1 - 0.0049 16.5 0.8 0.007 16.0 0.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase subunit beta OppC_N PF12911.7 KEZ35782.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C YjbE PF11106.8 KEZ35782.1 - 7.2 6.9 7.4 3.5 7.9 0.6 2.2 1 1 1 2 2 2 0 Exopolysaccharide production protein YjbE TIR_2 PF13676.6 KEZ35783.1 - 6e-35 120.4 0.0 8.8e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KEZ35783.1 - 1.3e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 TIR domain DUF309 PF03745.14 KEZ35784.1 - 8.3e-19 67.0 0.0 1.1e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF309) TPR_16 PF13432.6 KEZ35784.1 - 0.00068 20.2 0.8 0.0014 19.2 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ35784.1 - 0.0029 18.3 2.0 0.42 11.6 1.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat S-AdoMet_synt_C PF02773.16 KEZ35785.1 - 2.4e-64 215.5 0.0 3.7e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KEZ35785.1 - 5.2e-41 139.7 0.0 1e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KEZ35785.1 - 6.7e-38 129.4 0.0 1.2e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidohydro_1 PF01979.20 KEZ35786.1 - 1.7e-34 119.7 0.0 2e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ35786.1 - 1.4e-13 51.1 11.1 6.3e-11 42.4 4.8 2.2 2 0 0 2 2 2 2 Amidohydrolase family Hydrolase_4 PF12146.8 KEZ35788.1 - 1.1e-06 28.1 0.1 0.0083 15.4 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEZ35788.1 - 7e-06 26.1 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein PG_binding_1 PF01471.18 KEZ35790.1 - 3e-17 62.6 0.0 4.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain SLT PF01464.20 KEZ35790.1 - 1.2e-06 28.2 0.0 2.8e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Transglycosylase SLT domain PG_binding_3 PF09374.10 KEZ35790.1 - 5e-05 23.5 0.1 0.089 13.1 0.0 2.8 1 1 1 2 2 2 2 Predicted Peptidoglycan domain Lys PF00062.20 KEZ35790.1 - 0.00015 22.0 0.0 0.067 13.4 0.0 2.2 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family BTAD PF03704.17 KEZ35791.1 - 9.1e-42 142.9 11.1 1.3e-41 142.4 11.1 1.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_14 PF13428.6 KEZ35791.1 - 0.00096 19.8 12.2 0.07 14.0 0.5 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ35791.1 - 0.0047 17.5 11.0 0.34 11.6 2.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Trans_reg_C PF00486.28 KEZ35791.1 - 0.0066 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_19 PF14559.6 KEZ35791.1 - 0.034 14.7 1.0 2.2 8.8 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ35791.1 - 0.15 12.1 1.0 5.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ35791.1 - 1.1 9.6 3.7 27 5.2 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Asn_synthase PF00733.21 KEZ35792.1 - 4.6e-28 98.9 0.0 6.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase PqqD PF05402.12 KEZ35793.1 - 6.6e-14 52.0 0.0 8.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Cdc6_C PF09079.11 KEZ35793.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Transglut_core3 PF13471.6 KEZ35794.1 - 5.8e-27 93.9 3.8 7.6e-27 93.5 3.8 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily ABC_membrane PF00664.23 KEZ35795.1 - 3.7e-42 144.9 4.0 4.6e-42 144.6 4.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ35795.1 - 3.4e-30 105.3 0.0 5.3e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KEZ35795.1 - 2.7e-06 27.9 0.5 9.4e-06 26.1 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KEZ35795.1 - 2.9e-06 26.9 0.0 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEZ35795.1 - 0.0012 18.6 0.7 0.021 14.6 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEZ35795.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KEZ35795.1 - 0.0019 18.1 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEZ35795.1 - 0.0027 18.0 0.0 0.009 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KEZ35795.1 - 0.0085 16.6 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEZ35795.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KEZ35795.1 - 0.098 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF2207 PF09972.9 KEZ35795.1 - 0.66 8.7 3.4 1.3 7.7 3.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AMP-binding PF00501.28 KEZ35796.1 - 2.1e-67 227.6 1.3 4e-67 226.7 1.3 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ35796.1 - 8e-17 62.0 0.1 2.8e-16 60.3 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 KEZ35797.1 - 1.8e-88 296.4 0.4 1.1e-87 293.8 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEZ35797.1 - 1.1e-51 176.3 0.4 1.9e-51 175.5 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KEZ35797.1 - 1.1e-44 152.4 13.2 2.8e-27 95.8 4.0 2.8 3 0 0 3 3 2 2 KR domain Ketoacyl-synt_C PF02801.22 KEZ35797.1 - 5.7e-43 145.7 1.3 5.7e-43 145.7 1.3 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEZ35797.1 - 6.8e-16 58.4 0.1 5.6e-12 45.8 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KEZ35797.1 - 5.1e-15 56.2 2.9 1.1e-14 55.1 0.4 2.6 2 1 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 KEZ35797.1 - 5.3e-13 49.4 0.0 1.1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEZ35797.1 - 1e-10 41.4 1.3 1e-10 41.4 1.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KEZ35797.1 - 1.9e-08 34.0 0.2 6.5e-08 32.3 0.2 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KEZ35797.1 - 8.7e-08 32.0 1.1 2.6e-07 30.5 1.1 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.7 KEZ35797.1 - 4.8e-05 24.1 5.7 4.8e-05 24.1 5.7 8.4 4 2 2 6 6 2 1 Alpha/beta hydrolase family Epimerase PF01370.21 KEZ35797.1 - 0.0001 21.9 0.5 0.00017 21.1 0.5 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 KEZ35797.1 - 0.00094 19.1 0.0 0.0034 17.3 0.0 2.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_synt_2 PF02719.15 KEZ35797.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEZ35797.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Abhydrolase_1 PF00561.20 KEZ35797.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold NAD_binding_4 PF07993.12 KEZ35797.1 - 0.15 11.2 0.2 0.26 10.4 0.2 1.3 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.13 KEZ35797.1 - 0.2 11.2 0.3 0.38 10.3 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family TP_methylase PF00590.20 KEZ35799.1 - 1.1e-19 71.2 1.4 2.1e-19 70.3 1.4 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_25 PF13649.6 KEZ35799.1 - 0.043 14.5 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FCD PF07729.12 KEZ35800.1 - 5.7e-18 65.5 9.0 1.3e-17 64.3 9.0 1.7 1 1 0 1 1 1 1 FCD domain GntR PF00392.21 KEZ35800.1 - 7.5e-18 63.9 1.9 1.2e-17 63.2 0.4 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 KEZ35800.1 - 0.0033 17.7 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator HTH_20 PF12840.7 KEZ35800.1 - 0.019 15.0 1.9 0.042 13.9 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.12 KEZ35800.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Polysacc_deac_1 PF01522.21 KEZ35801.1 - 6.2e-29 100.4 0.0 8.5e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase CAP PF00188.26 KEZ35803.1 - 6.4e-17 62.6 0.1 9.3e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PT PF04886.12 KEZ35803.1 - 0.0014 18.1 7.2 0.0014 18.1 7.2 2.7 2 0 0 2 2 2 1 PT repeat CT_A_B PF02626.15 KEZ35804.1 - 5.7e-87 291.7 0.0 6.4e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 KEZ35805.1 - 4.3e-75 251.9 0.2 5e-75 251.7 0.2 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D LamB_YcsF PF03746.16 KEZ35806.1 - 5.4e-99 330.7 0.0 6.2e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family MarR_2 PF12802.7 KEZ35808.1 - 5.2e-10 39.1 0.8 1.2e-09 37.9 0.2 1.9 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KEZ35808.1 - 4.7e-05 23.2 0.1 7.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KEZ35808.1 - 0.0088 15.6 0.2 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KEZ35808.1 - 0.052 13.9 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Cob_adeno_trans PF01923.18 KEZ35808.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase HTH_Crp_2 PF13545.6 KEZ35808.1 - 0.099 12.6 0.4 0.38 10.8 0.1 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Abhydrolase_1 PF00561.20 KEZ35809.1 - 1.2e-18 67.7 0.1 1.9e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ35809.1 - 2.4e-16 61.0 18.0 3.5e-16 60.5 18.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ35809.1 - 1.8e-08 34.0 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cupin_2 PF07883.11 KEZ35810.1 - 2.9e-16 58.9 0.1 5.2e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEZ35810.1 - 3.6e-08 33.4 0.0 6.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain AraC_binding_2 PF14525.6 KEZ35810.1 - 0.00041 20.1 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 AraC-binding-like domain Cupin_1 PF00190.22 KEZ35810.1 - 0.00089 18.9 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KEZ35810.1 - 0.0013 18.5 0.2 0.0019 17.9 0.2 1.4 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 KEZ35810.1 - 0.0031 17.7 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like EutQ PF06249.12 KEZ35810.1 - 0.0034 17.1 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ ARD PF03079.14 KEZ35810.1 - 0.01 16.0 0.1 0.015 15.5 0.1 1.1 1 0 0 1 1 1 0 ARD/ARD' family DMSP_lyase PF16867.5 KEZ35810.1 - 0.014 15.1 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_3 PF05899.12 KEZ35810.1 - 0.048 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pyrophosphatase PF00719.19 KEZ35811.1 - 0.074 12.9 0.6 0.11 12.3 0.6 1.4 1 1 0 1 1 1 0 Inorganic pyrophosphatase Pyridox_ox_2 PF12900.7 KEZ35812.1 - 4.4e-35 120.7 0.7 5.4e-35 120.4 0.7 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase OrfB_Zn_ribbon PF07282.11 KEZ35814.1 - 2.3e-22 78.7 1.6 3e-22 78.3 1.6 1.2 1 0 0 1 1 1 1 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 KEZ35814.1 - 0.00014 21.3 2.6 0.0078 15.7 1.1 2.0 1 1 1 2 2 2 2 TFIIB zinc-binding HypA PF01155.19 KEZ35814.1 - 0.0019 18.2 1.0 0.002 18.1 1.0 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KEZ35814.1 - 0.0036 16.7 0.9 0.87 9.1 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain TackOD1 PF18551.1 KEZ35814.1 - 0.007 16.1 1.0 0.0083 15.8 1.0 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 DZR PF12773.7 KEZ35814.1 - 0.012 15.6 4.2 0.025 14.6 4.3 1.5 1 1 1 2 2 2 0 Double zinc ribbon zf-Mss51 PF13824.6 KEZ35814.1 - 0.019 15.1 3.3 0.068 13.3 3.3 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Rubredoxin_2 PF18073.1 KEZ35814.1 - 0.027 14.2 5.5 0.56 10.0 0.7 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_10 PF10058.9 KEZ35814.1 - 0.028 14.2 2.2 0.72 9.6 2.5 2.1 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 KEZ35814.1 - 0.031 14.2 5.3 1.5 8.8 0.3 2.2 1 1 1 2 2 2 0 zinc-ribbon domain HalOD2 PF18547.1 KEZ35814.1 - 0.041 13.8 4.1 0.75 9.7 0.2 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_17 PF17120.5 KEZ35814.1 - 0.053 13.1 5.6 1.7 8.3 0.3 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-3CxxC PF13695.6 KEZ35814.1 - 0.061 13.8 1.8 0.59 10.6 0.3 2.0 1 1 1 2 2 2 0 Zinc-binding domain zn-ribbon_14 PF16503.5 KEZ35814.1 - 0.12 11.9 1.1 12 5.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon UPF0547 PF10571.9 KEZ35814.1 - 0.15 12.2 4.7 0.24 11.5 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Auto_anti-p27 PF06677.12 KEZ35814.1 - 0.15 12.2 1.1 0.23 11.6 1.1 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 KEZ35814.1 - 0.22 11.7 5.3 3.5 7.8 0.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Ribosomal_L37e PF01907.19 KEZ35814.1 - 0.38 10.9 5.9 2.9 8.1 0.3 2.1 1 1 1 2 2 2 0 Ribosomal protein L37e zinc_ribbon_2 PF13240.6 KEZ35814.1 - 1 9.2 4.5 26 4.7 0.5 2.3 1 1 1 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KEZ35814.1 - 1.2 8.9 7.5 4.3 7.1 0.9 2.1 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S14 PF00253.21 KEZ35814.1 - 1.6 8.6 5.1 3.6 7.4 0.3 2.2 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zinc_ribbon_5 PF13719.6 KEZ35814.1 - 2.9 7.7 8.2 5 7.0 1.3 2.2 1 1 1 2 2 2 0 zinc-ribbon domain PAPS_reduct PF01507.19 KEZ35816.1 - 0.00027 21.0 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family OrfB_IS605 PF01385.19 KEZ35817.1 - 4.1e-27 94.8 1.0 6e-27 94.3 1.0 1.2 1 0 0 1 1 1 1 Probable transposase OrfB_Zn_ribbon PF07282.11 KEZ35817.1 - 6.9e-21 73.9 0.1 1.2e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 KEZ35817.1 - 3.7e-14 51.9 0.0 7.3e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain zf-piccolo PF05715.13 KEZ35817.1 - 0.00071 19.7 1.2 0.0013 18.9 1.2 1.3 1 0 0 1 1 1 1 Piccolo Zn-finger Zn_Tnp_IS1595 PF12760.7 KEZ35817.1 - 0.06 13.3 0.9 0.13 12.3 0.9 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 KEZ35817.1 - 0.079 13.0 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KEZ35817.1 - 0.12 11.9 0.3 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RanBP PF00641.18 KEZ35817.1 - 0.61 9.5 2.3 16 4.9 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Y1_Tnp PF01797.16 KEZ35818.1 - 9.9e-43 145.1 0.0 1.1e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS200 like PCMT PF01135.19 KEZ35819.1 - 2.1e-13 50.5 0.0 5e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KEZ35819.1 - 5.7e-07 30.2 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ35819.1 - 2.4e-05 23.9 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KEZ35819.1 - 5.1e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35819.1 - 0.00055 20.6 0.0 0.0019 18.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KEZ35819.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KEZ35819.1 - 0.0033 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ35819.1 - 0.034 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KEZ35819.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KEZ35819.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 KEZ35819.1 - 0.31 10.1 0.0 0.45 9.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Radical_SAM PF04055.21 KEZ35820.1 - 1.4e-11 45.0 0.0 2.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ35820.1 - 0.00043 20.6 0.0 0.0007 19.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ35820.1 - 0.00047 20.3 0.0 0.00077 19.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 KEZ35820.1 - 0.00065 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain DUF2889 PF11136.8 KEZ35820.1 - 0.14 12.5 0.2 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) YdaS_antitoxin PF15943.5 KEZ35821.1 - 0.31 11.0 3.5 22 5.0 0.0 3.7 4 1 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HD_4 PF13328.6 KEZ35823.1 - 1.8e-05 24.6 0.4 0.00059 19.6 0.1 2.3 1 1 0 2 2 2 2 HD domain Se-cys_synth_N PF12390.8 KEZ35824.1 - 0.025 14.8 4.5 0.052 13.8 4.5 1.6 1 0 0 1 1 1 0 Selenocysteine synthase N terminal DUF294_C PF10335.9 KEZ35825.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain TPR_MalT PF17874.1 KEZ35826.1 - 2.1e-05 24.1 1.9 0.00021 20.8 0.0 2.8 2 1 1 3 3 3 1 MalT-like TPR region HTH_3 PF01381.22 KEZ35826.1 - 0.018 15.1 0.4 0.084 12.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix YdaS_antitoxin PF15943.5 KEZ35826.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TPR_16 PF13432.6 KEZ35826.1 - 1.1 9.9 34.1 0.46 11.2 0.9 5.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ35826.1 - 3.2 8.3 10.0 4.7 7.8 1.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ35826.1 - 5 8.2 16.3 8.5 7.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ35826.1 - 9.6 6.6 9.1 44 4.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Acetyltransf_3 PF13302.7 KEZ35827.1 - 6.4e-31 107.9 0.2 7.8e-31 107.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ35827.1 - 3.8e-08 33.6 0.0 4.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEZ35827.1 - 0.00037 20.2 0.0 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SnoaL_3 PF13474.6 KEZ35827.1 - 0.076 13.3 0.2 0.18 12.1 0.0 1.7 1 1 1 2 2 2 0 SnoaL-like domain DUF1611_N PF17396.2 KEZ35828.1 - 0.12 12.6 0.0 0.48 10.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Sigma70_r4 PF04545.16 KEZ35829.1 - 0.0018 17.8 0.1 0.0028 17.2 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.7 KEZ35829.1 - 0.0021 18.2 0.0 0.0063 16.7 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ35829.1 - 0.0025 17.9 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 KEZ35829.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain YdaS_antitoxin PF15943.5 KEZ35829.1 - 0.01 15.7 0.1 0.026 14.4 0.0 1.8 1 1 1 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_7 PF02796.15 KEZ35829.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Phage_AlpA PF05930.12 KEZ35829.1 - 0.014 15.2 0.2 0.025 14.4 0.2 1.4 1 1 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) MarR_2 PF12802.7 KEZ35829.1 - 0.026 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 KEZ35829.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain KORA PF16509.5 KEZ35829.1 - 0.1 12.9 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_11 PF08279.12 KEZ35829.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.12 KEZ35829.1 - 0.15 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Bro-N PF02498.17 KEZ35831.1 - 3.9e-26 91.6 0.0 9.8e-26 90.3 0.0 1.7 2 0 0 2 2 2 1 BRO family, N-terminal domain ANT PF03374.14 KEZ35831.1 - 1.9e-12 47.5 0.0 3.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Phage antirepressor protein KilAC domain ADPrib_exo_Tox PF03496.14 KEZ35833.1 - 4e-37 127.5 0.0 2.7e-17 62.8 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosyltransferase exoenzyme zf-TRM13_CCCH PF11722.8 KEZ35833.1 - 0.029 14.1 0.2 0.049 13.4 0.2 1.3 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein FTP PF07504.13 KEZ35833.1 - 0.08 12.8 0.1 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Fungalysin/Thermolysin Propeptide Motif ADPrib_exo_Tox PF03496.14 KEZ35835.1 - 7.4e-19 67.9 0.0 1.3e-18 67.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 KEZ35835.1 - 0.0029 16.9 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 KEZ35836.1 - 7.1e-12 45.1 0.0 2e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme HTH_38 PF13936.6 KEZ35838.1 - 0.00049 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GcrA PF07750.11 KEZ35838.1 - 0.00089 19.7 1.2 0.0012 19.3 1.2 1.2 1 0 0 1 1 1 1 GcrA cell cycle regulator HTH_Tnp_Tc3_1 PF11427.8 KEZ35838.1 - 0.0036 17.1 0.1 0.0064 16.3 0.1 1.4 1 0 0 1 1 1 1 Tc3 transposase MarR PF01047.22 KEZ35838.1 - 0.0099 15.8 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 1 MarR family DUF2774 PF11242.8 KEZ35838.1 - 0.16 12.2 1.1 4.5 7.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2774) HNH PF01844.23 KEZ35839.1 - 7.7e-09 35.6 0.4 7.7e-09 35.6 0.4 1.9 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 KEZ35839.1 - 8.7e-09 35.1 0.6 2e-08 34.0 0.6 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KEZ35839.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 HNH endonuclease E3_UbLigase_RBR PF18091.1 KEZ35839.1 - 1.7 8.9 11.4 45 4.3 0.4 4.3 2 2 2 4 4 4 0 E3 Ubiquitin Ligase RBR C-terminal domain Terminase_6 PF03237.15 KEZ35840.1 - 4e-10 39.7 0.0 9.3e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 Terminase-like family Terminase_3 PF04466.13 KEZ35840.1 - 0.00057 19.5 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Phage terminase large subunit Terminase_6C PF17289.2 KEZ35840.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Terminase RNaseH-like domain Terminase_3C PF17288.2 KEZ35840.1 - 0.19 12.1 0.1 2.1 8.7 0.0 2.3 2 1 1 3 3 3 0 Terminase RNAseH like domain DUF3043 PF11241.8 KEZ35842.1 - 0.12 12.4 14.0 0.15 12.1 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4407 PF14362.6 KEZ35842.1 - 1.2 8.5 11.2 1.4 8.2 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3090 PF11290.8 KEZ35845.1 - 1 9.1 2.6 0.97 9.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DUF1445 PF07286.12 KEZ35846.1 - 0.028 14.3 0.1 0.038 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) Phage_prot_Gp6 PF05133.14 KEZ35847.1 - 0.0024 17.0 0.0 1 8.4 0.0 2.8 3 0 0 3 3 3 2 Phage portal protein, SPP1 Gp6-like N6_N4_Mtase PF01555.18 KEZ35848.1 - 3.1e-22 79.4 0.0 8.7e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 KEZ35848.1 - 0.00074 19.2 0.0 0.8 9.3 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KEZ35848.1 - 0.003 17.2 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KEZ35848.1 - 0.0099 15.6 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KEZ35848.1 - 0.17 12.6 0.1 0.45 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Phage_min_cap2 PF06152.11 KEZ35851.1 - 4e-43 147.7 0.0 3.4e-37 128.2 0.0 2.2 2 0 0 2 2 2 2 Phage minor capsid protein 2 Minor_capsid_2 PF11114.8 KEZ35853.1 - 0.046 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Minor capsid protein Glycogen_syn PF05693.13 KEZ35854.1 - 0.11 11.1 0.1 0.1 11.1 0.1 1.0 1 0 0 1 1 1 0 Glycogen synthase zf-4CXXC_R1 PF10497.9 KEZ35854.1 - 0.19 11.9 3.5 0.17 12.1 0.7 1.9 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 MDFI PF15316.6 KEZ35855.1 - 3.5 7.7 4.1 5.2 7.1 4.1 1.4 1 1 0 1 1 1 0 MyoD family inhibitor OrfB_Zn_ribbon PF07282.11 KEZ35856.1 - 2.9e-23 81.6 0.1 3.4e-23 81.3 0.1 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HypA PF01155.19 KEZ35856.1 - 0.0039 17.2 0.1 0.0048 16.9 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_10 PF10058.9 KEZ35856.1 - 0.012 15.3 1.7 0.25 11.1 2.0 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 KEZ35856.1 - 0.027 14.2 3.8 1.8 8.4 0.4 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 KEZ35856.1 - 0.028 13.8 1.2 3 7.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KEZ35856.1 - 0.028 13.9 1.7 0.1 12.2 1.9 1.7 1 1 1 2 2 2 0 TFIIB zinc-binding Tnp_zf-ribbon_2 PF13842.6 KEZ35856.1 - 0.073 13.9 2.4 0.36 11.7 2.0 1.9 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2_11 PF16622.5 KEZ35856.1 - 0.13 12.1 5.3 1.7 8.5 0.2 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 KEZ35856.1 - 0.14 12.1 3.1 3.7 7.5 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 KEZ35856.1 - 0.16 11.8 1.6 6.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.7 KEZ35856.1 - 0.18 11.9 3.9 0.6 10.2 3.9 1.7 1 1 1 2 2 2 0 Double zinc ribbon UPF0547 PF10571.9 KEZ35856.1 - 0.22 11.6 5.9 0.72 10.0 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HalOD2 PF18547.1 KEZ35856.1 - 0.24 11.3 3.7 4.3 7.3 0.2 2.4 1 1 1 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_17 PF17120.5 KEZ35856.1 - 0.29 10.8 5.8 1 9.1 0.8 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type DNA_RNApol_7kD PF03604.13 KEZ35856.1 - 0.32 10.7 6.1 3 7.6 6.2 2.0 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.6 KEZ35856.1 - 0.35 11.0 3.1 2.4 8.3 3.1 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.10 KEZ35856.1 - 2.9 8.1 5.5 14 5.9 5.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Biotin_lipoyl PF00364.22 KEZ35857.1 - 7.7e-20 70.5 0.0 1.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 KEZ35857.1 - 0.0013 18.6 0.1 0.002 18.0 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 KEZ35857.1 - 0.026 13.8 0.1 0.095 11.9 0.0 1.7 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KEZ35857.1 - 0.038 14.7 1.3 1.8 9.3 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Transket_pyr PF02779.24 KEZ35858.1 - 3.9e-47 160.2 0.0 5.1e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ35858.1 - 2.7e-34 117.7 0.0 5.7e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KEZ35859.1 - 1.3e-74 250.9 0.0 1.7e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEZ35859.1 - 0.045 13.0 0.0 0.14 11.4 0.0 1.6 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KEZ35859.1 - 0.046 13.5 0.3 1.6 8.5 0.3 2.3 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Bac_luciferase PF00296.20 KEZ35860.1 - 7e-21 74.9 10.4 2e-20 73.4 10.4 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase Thyroglob_assoc PF16597.5 KEZ35860.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain PGA_cap PF09587.10 KEZ35861.1 - 1.3e-63 214.9 0.5 1.5e-63 214.6 0.5 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap LSDAT_prok PF18171.1 KEZ35861.1 - 0.046 13.0 0.1 0.21 10.8 0.1 2.0 1 1 0 1 1 1 0 SLOG in TRPM, prokaryote FUR PF01475.19 KEZ35862.1 - 5.1e-29 100.9 0.0 6.2e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 KEZ35862.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Tir_receptor_N PF07490.11 KEZ35862.1 - 0.011 15.5 0.1 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Aminotran_1_2 PF00155.21 KEZ35865.1 - 1.5e-49 169.1 0.0 1.7e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEZ35865.1 - 1.8e-08 34.1 0.0 2.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEZ35865.1 - 0.0045 16.0 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KEZ35865.1 - 0.014 13.9 0.0 0.024 13.2 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KEZ35865.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase ParBc_2 PF08857.11 KEZ35867.1 - 0.2 11.7 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative ParB-like nuclease Ammonium_transp PF00909.21 KEZ35868.1 - 0.085 11.5 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Ammonium Transporter Family DUF222 PF02720.17 KEZ35869.1 - 7.3e-22 78.2 0.8 1.2e-21 77.6 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 KEZ35869.1 - 7e-06 26.1 3.0 7e-06 26.1 3.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Trypsin_2 PF13365.6 KEZ35871.1 - 3.4e-31 109.2 5.9 3.4e-31 109.2 5.9 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KEZ35871.1 - 1.2e-18 67.2 1.8 1.3e-18 67.0 0.3 1.9 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 KEZ35871.1 - 7.4e-13 48.8 4.9 1.2e-12 48.1 4.9 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KEZ35871.1 - 5e-12 45.5 0.3 1.2e-11 44.2 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEZ35871.1 - 1.8e-08 34.6 0.3 5.6e-08 33.0 0.3 1.9 1 1 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KEZ35871.1 - 0.0016 17.2 5.2 0.017 13.8 0.3 2.1 2 0 0 2 2 2 2 Peptidase S46 MscL PF01741.18 KEZ35872.1 - 1.5e-37 128.6 0.5 1.7e-37 128.4 0.5 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL SecE PF00584.20 KEZ35872.1 - 1.2 9.1 11.0 0.077 12.9 3.5 2.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Lpp-LpqN PF10738.9 KEZ35873.1 - 0.0023 17.4 0.3 0.005 16.3 0.3 1.7 1 1 0 1 1 1 1 Probable lipoprotein LpqN Esterase_phd PF10503.9 KEZ35874.1 - 2.7e-08 33.6 0.4 2.7e-08 33.6 0.4 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 KEZ35874.1 - 0.00032 20.4 0.0 0.00066 19.4 0.0 1.4 1 1 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KEZ35874.1 - 0.00037 19.9 0.0 0.00052 19.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KEZ35874.1 - 0.00098 18.5 0.3 0.0017 17.6 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KEZ35874.1 - 0.0045 16.8 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KEZ35874.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KEZ35874.1 - 0.058 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KEZ35874.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ35874.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold TM_helix PF05552.12 KEZ35876.1 - 2.9e-09 36.7 6.9 1.3e-07 31.4 0.1 3.2 3 0 0 3 3 3 2 Conserved TM helix UPF0114 PF03350.16 KEZ35876.1 - 0.12 12.6 0.2 0.12 12.6 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 UDG PF03167.19 KEZ35877.1 - 3e-32 111.7 0.0 3.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily YkuD PF03734.14 KEZ35878.1 - 6.4e-19 68.8 0.0 1e-18 68.2 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PNP_phzG_C PF10590.9 KEZ35881.1 - 4e-20 71.6 0.0 9e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KEZ35881.1 - 1.9e-19 69.6 0.0 3.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KEZ35881.1 - 0.15 12.7 0.0 0.22 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TIR_2 PF13676.6 KEZ35882.1 - 3.6e-13 50.2 0.0 4e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 TIR domain Citrate_synt PF00285.21 KEZ35883.1 - 7.8e-84 281.8 0.3 1.1e-82 278.1 0.3 1.9 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain HAT PF02184.16 KEZ35883.1 - 0.029 14.3 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Aminotran_5 PF00266.19 KEZ35884.1 - 1.7e-15 56.8 0.0 4.7e-14 52.1 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Citrate_synt PF00285.21 KEZ35885.1 - 4.5e-134 447.1 0.0 5.6e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Response_reg PF00072.24 KEZ35886.1 - 4.1e-16 59.1 0.0 6.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ35886.1 - 3.1e-15 55.4 0.0 5.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ35886.1 - 0.00027 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ35886.1 - 0.023 14.2 0.1 0.058 12.9 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 B12-binding PF02310.19 KEZ35886.1 - 0.023 14.8 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain HTH_40 PF14493.6 KEZ35886.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HisKA_3 PF07730.13 KEZ35887.1 - 2.8e-11 43.8 7.8 2.8e-11 43.8 7.8 2.5 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 KEZ35887.1 - 0.00021 21.7 0.2 0.0057 17.1 0.2 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KEZ35887.1 - 0.0047 16.9 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain MarR PF01047.22 KEZ35888.1 - 1.6e-18 66.3 0.1 2.2e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 KEZ35888.1 - 2.6e-13 49.6 0.2 2.6e-13 49.6 0.2 2.5 2 1 1 3 3 3 1 MarR family HTH_27 PF13463.6 KEZ35888.1 - 1.4e-06 28.7 0.1 3.8e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 KEZ35888.1 - 0.00048 20.4 0.1 0.0012 19.1 0.0 1.8 2 1 0 2 2 2 1 Transcriptional regulator SMC_ScpB PF04079.16 KEZ35888.1 - 0.001 18.7 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_IclR PF09339.10 KEZ35888.1 - 0.0019 17.9 7.3 0.0052 16.6 0.2 3.3 3 1 1 4 4 4 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KEZ35888.1 - 0.011 15.3 0.1 5.2 6.7 0.2 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KEZ35888.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 KEZ35888.1 - 0.019 15.0 0.1 0.019 15.0 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HxlR PF01638.17 KEZ35888.1 - 0.045 13.6 0.6 0.13 12.1 0.0 2.0 2 1 1 3 3 3 0 HxlR-like helix-turn-helix Fe_dep_repress PF01325.19 KEZ35888.1 - 0.058 13.6 0.0 0.9 9.8 0.0 2.3 2 1 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 KEZ35888.1 - 0.27 11.3 5.9 0.28 11.2 0.5 2.8 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain GFO_IDH_MocA PF01408.22 KEZ35889.1 - 5.7e-09 36.8 0.1 1e-08 36.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glycos_transf_2 PF00535.26 KEZ35889.1 - 0.0067 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 VWA_3 PF13768.6 KEZ35889.1 - 0.027 14.4 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain CoA_binding_2 PF13380.6 KEZ35889.1 - 0.072 13.6 0.5 0.32 11.5 0.6 1.9 1 1 1 2 2 2 0 CoA binding domain LigT_PEase PF02834.16 KEZ35890.1 - 3.6e-20 71.9 0.4 5.6e-12 45.7 0.1 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 KEZ35890.1 - 6.7e-12 45.6 0.0 1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Trans_reg_C PF00486.28 KEZ35891.1 - 2.1e-21 75.8 0.1 2.8e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Sulfotransfer_3 PF13469.6 KEZ35893.1 - 1e-14 55.4 0.0 1.9e-14 54.6 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KEZ35893.1 - 1.8e-09 37.4 0.0 6.4e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain DUF2530 PF10745.9 KEZ35894.1 - 4e-08 33.4 1.1 5.9e-08 32.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) Phage_holin_3_6 PF07332.11 KEZ35894.1 - 0.0026 17.8 1.9 0.0035 17.4 1.9 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III MFS_2 PF13347.6 KEZ35894.1 - 0.034 12.7 0.0 0.038 12.5 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4131 PF13567.6 KEZ35894.1 - 0.05 13.3 1.6 0.064 12.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SYS1 PF09801.9 KEZ35894.1 - 0.33 11.1 2.0 0.6 10.2 1.9 1.4 1 1 1 2 2 2 0 Integral membrane protein S linking to the trans Golgi network CcmD PF04995.14 KEZ35894.1 - 8.2 6.6 8.2 3.9 7.6 2.4 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) HATPase_c_3 PF13589.6 KEZ35895.1 - 0.00085 19.2 0.0 0.0018 18.1 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCA_ABC_TP_C PF12399.8 KEZ35895.1 - 0.025 14.5 0.1 0.11 12.4 0.1 2.3 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter HATPase_c PF02518.26 KEZ35895.1 - 0.17 12.4 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SCP_3 PF17844.1 KEZ35896.1 - 3.2e-36 123.0 0.5 8.8e-36 121.6 0.5 1.8 1 0 0 1 1 1 1 Bacterial SCP ortholog MDMPI_N PF11716.8 KEZ35896.1 - 6.6e-30 104.6 12.0 6.6e-30 104.6 12.0 2.4 3 0 0 3 3 3 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 KEZ35896.1 - 4.7e-08 33.8 4.0 4.7e-08 33.8 4.0 3.2 3 1 1 4 4 4 1 MDMPI C-terminal domain DinB_2 PF12867.7 KEZ35896.1 - 4.5e-05 24.0 0.7 0.0043 17.5 0.2 1.9 1 1 1 2 2 2 2 DinB superfamily TetR_C_15 PF17918.1 KEZ35896.1 - 0.13 13.0 0.6 0.13 13.0 0.6 2.9 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain GATase_6 PF13522.6 KEZ35897.1 - 3e-15 56.6 0.1 5.8e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEZ35897.1 - 5.5e-15 55.4 0.0 9.8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KEZ35897.1 - 4.9e-09 35.9 0.1 1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_2 PF00310.21 KEZ35897.1 - 1.6e-06 27.1 1.3 0.0076 15.0 0.0 3.1 2 1 1 3 3 3 3 Glutamine amidotransferases class-II GATase_4 PF13230.6 KEZ35897.1 - 9.8e-05 21.4 0.1 0.00033 19.6 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Trypan_PARP PF05887.11 KEZ35897.1 - 0.061 13.3 3.7 0.14 12.1 3.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AIRS_C PF02769.22 KEZ35898.1 - 1.4e-26 93.5 0.1 3e-26 92.4 0.1 1.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KEZ35898.1 - 3.3e-15 56.5 5.0 5.4e-15 55.8 2.7 2.3 1 1 1 2 2 2 1 AIR synthase related protein, N-terminal domain DUF3073 PF11273.8 KEZ35899.1 - 2.5e-21 76.2 5.9 2.9e-21 75.9 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3073) ELFV_dehydrog_N PF02812.18 KEZ35900.1 - 5.4e-25 87.8 0.0 1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KEZ35900.1 - 4.4e-17 62.6 1.1 9.5e-09 35.3 0.0 2.4 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 KEZ35900.1 - 0.015 15.4 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 KEZ35900.1 - 0.018 15.5 0.5 0.042 14.3 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KEZ35900.1 - 0.032 13.6 0.0 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_6 PF13174.6 KEZ35901.1 - 0.053 14.2 1.0 2.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ35901.1 - 0.22 12.3 6.1 3.2 8.6 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ35901.1 - 0.24 12.1 7.7 0.53 11.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ35901.1 - 0.78 10.7 6.9 9.6 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_17 PF12728.7 KEZ35902.1 - 1.2e-10 41.4 0.1 1.4e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 KEZ35902.1 - 9.6e-07 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 KEZ35902.1 - 6.4e-06 26.2 0.0 7.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_29 PF13551.6 KEZ35902.1 - 0.091 12.8 0.1 0.21 11.6 0.1 1.6 1 1 1 2 2 2 0 Winged helix-turn helix DDE_Tnp_1_6 PF13751.6 KEZ35904.1 - 3.4e-18 66.1 0.2 6e-18 65.3 0.2 1.4 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 KEZ35904.1 - 1.6e-13 50.5 0.0 8.1e-13 48.2 0.0 2.2 2 0 0 2 2 2 1 Transposase domain (DUF772) Podovirus_Gp16 PF05894.12 KEZ35904.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) PEP-utilizers PF00391.23 KEZ35904.1 - 2.4 7.9 4.3 0.7 9.6 0.1 2.2 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain SnoaL_2 PF12680.7 KEZ35906.1 - 6.8e-15 55.6 0.7 7.8e-15 55.4 0.7 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KEZ35906.1 - 0.0018 18.1 0.0 0.0062 16.3 0.1 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KEZ35906.1 - 0.0065 16.9 0.1 0.0073 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 KEZ35906.1 - 0.012 15.7 0.1 0.018 15.2 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain MLTR_LBD PF17765.1 KEZ35907.1 - 1.7e-35 122.6 0.3 1.9e-35 122.4 0.3 1.0 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain DDE_5 PF13546.6 KEZ35908.1 - 2.8e-24 85.9 6.4 5.5e-24 85.0 6.4 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Glycos_transf_2 PF00535.26 KEZ35910.1 - 6.9e-16 58.5 0.0 9.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ35910.1 - 9.3e-07 29.0 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Lipase_GDSL_2 PF13472.6 KEZ35911.1 - 6.2e-08 33.2 0.1 0.023 15.1 0.1 3.4 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ35911.1 - 5.8e-06 26.4 0.0 1.7e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4858 PF16150.5 KEZ35911.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) Dioxygenase_C PF00775.21 KEZ35912.1 - 3.5e-11 42.9 0.0 6.4e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Dioxygenase AAA_19 PF13245.6 KEZ35914.1 - 5e-16 59.3 0.0 3e-15 56.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KEZ35914.1 - 3.3e-15 56.4 0.0 1.7e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEZ35914.1 - 2e-09 37.3 0.0 3.5e-08 33.2 0.0 2.0 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KEZ35914.1 - 4.5e-06 26.4 0.2 0.028 14.2 0.1 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ35914.1 - 0.0017 18.1 0.0 0.4 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ35914.1 - 0.076 12.7 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP39 PF14980.6 KEZ35914.1 - 0.1 12.5 2.0 0.39 10.6 2.0 2.0 1 0 0 1 1 1 0 TIP39 peptide HTH_32 PF13565.6 KEZ35914.1 - 4.2 8.1 10.5 0.13 12.9 1.1 3.2 3 1 1 4 4 4 0 Homeodomain-like domain OrfB_IS605 PF01385.19 KEZ35915.1 - 4.9e-22 78.4 0.5 6.1e-22 78.1 0.5 1.1 1 0 0 1 1 1 1 Probable transposase Met_synt_B12 PF02965.17 KEZ35916.1 - 9e-96 320.5 0.0 2.6e-95 319.0 0.0 1.7 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 KEZ35916.1 - 1.7e-77 260.9 0.0 2.6e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 KEZ35916.1 - 1.1e-51 175.9 0.6 1.8e-50 171.9 0.1 2.4 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 KEZ35916.1 - 3.4e-27 94.7 0.1 1.2e-26 92.9 0.1 2.1 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 KEZ35916.1 - 1.1e-17 64.1 4.5 1.4e-16 60.6 1.0 3.3 3 0 0 3 3 3 1 B12 binding domain Transposase_20 PF02371.16 KEZ35917.1 - 9.7e-18 64.3 0.1 2.3e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 KEZ35917.1 - 5.2e-12 45.9 0.1 1.5e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Transposase CCDC23 PF15674.5 KEZ35918.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 DDE_3 PF13358.6 KEZ35919.1 - 3.3e-11 43.1 0.0 4.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 KEZ35919.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain MFS_1 PF07690.16 KEZ35920.1 - 3.4e-09 36.1 6.4 4.1e-09 35.8 6.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2721 PF11026.8 KEZ35920.1 - 0.26 11.2 3.9 2 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Ceramidase PF05875.12 KEZ35921.1 - 1.2e-10 41.3 3.3 1.4e-10 41.0 3.3 1.1 1 0 0 1 1 1 1 Ceramidase Phage_holin_2_4 PF16082.5 KEZ35921.1 - 0.59 9.9 2.2 7.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DPM3 PF08285.11 KEZ35921.1 - 1.1 9.5 3.9 3.4 7.9 0.2 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) kleA_kleC PF17383.2 KEZ35922.1 - 4.7 7.6 7.0 0.51 10.7 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Polysacc_synt PF01943.17 KEZ35923.1 - 8.4 5.7 17.1 0.17 11.2 6.7 2.8 2 2 0 2 2 2 0 Polysaccharide biosynthesis protein PMT_2 PF13231.6 KEZ35924.1 - 9.3e-32 110.4 14.3 9.3e-32 110.4 14.3 3.8 2 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 KEZ35924.1 - 1.1e-07 31.7 14.1 1.1e-07 31.7 14.1 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Bac_luciferase PF00296.20 KEZ35925.1 - 3.2e-65 220.6 6.5 3.6e-65 220.5 6.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase XdhC_C PF13478.6 KEZ35926.1 - 1.3e-44 151.7 0.1 2.8e-44 150.6 0.1 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 KEZ35926.1 - 3e-32 110.6 27.8 9.6e-24 83.4 7.8 3.4 3 1 0 3 3 3 2 XdhC and CoxI family SnoaL PF07366.12 KEZ35927.1 - 2e-15 56.7 0.0 2.6e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEZ35927.1 - 3.8e-05 24.3 0.3 7.1e-05 23.4 0.2 1.5 1 1 0 1 1 1 1 SnoaL-like domain Glyco_hydro_32N PF00251.20 KEZ35928.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Sulfotransfer_3 PF13469.6 KEZ35929.1 - 4.2e-23 82.9 1.1 9.8e-21 75.1 1.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KEZ35929.1 - 5.1e-19 68.8 0.0 1.8e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_2 PF03567.14 KEZ35929.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_4 PF17784.1 KEZ35929.1 - 0.11 12.4 0.8 1.3 8.8 0.8 2.5 1 1 0 1 1 1 0 Sulfotransferase domain DUF2237 PF09996.9 KEZ35930.1 - 1.3e-51 173.4 0.0 1.5e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) AAA_19 PF13245.6 KEZ35932.1 - 9.2e-08 32.5 0.0 0.0075 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KEZ35932.1 - 5.7e-07 29.4 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KEZ35932.1 - 8.7e-06 25.5 0.1 2.9e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ35932.1 - 0.00015 21.6 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KEZ35932.1 - 0.00017 21.1 0.0 0.053 13.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 KEZ35932.1 - 0.0041 16.4 1.0 0.02 14.2 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 KEZ35932.1 - 0.0084 15.5 0.0 0.074 12.4 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KEZ35932.1 - 0.047 14.1 1.2 0.76 10.1 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain DEAD PF00270.29 KEZ35932.1 - 0.055 13.2 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KEZ35932.1 - 0.063 13.0 0.0 5.2 6.7 0.0 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KEZ35932.1 - 0.11 12.8 0.0 18 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KEZ35932.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KEZ35932.1 - 0.22 11.3 0.0 1.3 8.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TetR_N PF00440.23 KEZ35933.1 - 7.3e-17 60.9 0.6 2.4e-16 59.3 0.6 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family AbiEi_4 PF13338.6 KEZ35933.1 - 0.045 13.9 0.8 0.21 11.8 0.0 2.6 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin DUF2726 PF10881.8 KEZ35933.1 - 0.048 13.6 0.4 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) DUF4179 PF13786.6 KEZ35933.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Glyoxalase PF00903.25 KEZ35934.1 - 1.5e-09 38.1 0.0 5.1e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEZ35934.1 - 2.9e-07 31.2 0.2 4.1e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KEZ35934.1 - 0.0003 20.7 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KEZ35934.1 - 0.09 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain HATPase_c PF02518.26 KEZ35935.1 - 4.7e-20 72.2 0.0 7.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ35935.1 - 8.9e-12 44.9 0.7 8.9e-12 44.9 0.7 2.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ35935.1 - 3.7e-06 27.2 5.4 2.1e-05 24.8 5.4 2.5 1 1 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 KEZ35935.1 - 5.4e-06 26.4 0.0 0.01 15.8 0.0 2.9 1 1 1 2 2 2 2 Histidine kinase-like ATPase domain Response_reg PF00072.24 KEZ35936.1 - 8.1e-27 93.6 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ35936.1 - 8.7e-25 86.6 0.0 1.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal BacA PF02673.18 KEZ35937.1 - 1.4e-72 244.5 0.0 2.6e-72 243.6 0.0 1.4 1 1 0 1 1 1 1 Bacitracin resistance protein BacA Amidase PF01425.21 KEZ35938.1 - 6.4e-56 190.2 7.2 1.4e-35 123.2 6.9 3.3 1 1 1 3 3 3 3 Amidase THF_DHG_CYH_C PF02882.19 KEZ35939.1 - 0.24 10.7 0.1 0.29 10.4 0.1 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_11 PF13531.6 KEZ35941.1 - 1.3e-43 149.4 8.1 1.6e-43 149.1 8.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KEZ35941.1 - 8.5e-18 65.4 7.1 1.7e-09 38.1 0.4 2.2 1 1 0 2 2 2 2 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 KEZ35941.1 - 1.6e-06 28.0 8.9 4e-06 26.7 4.2 2.1 1 1 0 2 2 2 1 PBP superfamily domain SBP_bac_6 PF13343.6 KEZ35941.1 - 0.0024 17.3 0.1 0.004 16.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 KEZ35941.1 - 0.0044 16.2 0.0 0.019 14.1 0.0 2.0 1 1 0 1 1 1 1 PBP superfamily domain GST_N_5 PF18485.1 KEZ35941.1 - 0.052 13.9 2.5 21 5.6 0.0 3.5 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain LysR_substrate PF03466.20 KEZ35941.1 - 0.081 12.3 0.0 0.35 10.2 0.0 2.0 1 1 0 1 1 1 0 LysR substrate binding domain AMP-binding PF00501.28 KEZ35942.1 - 2e-62 211.2 0.0 2.6e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KEZ35942.1 - 4.4e-21 76.1 0.3 1.9e-18 67.4 0.5 2.4 2 0 0 2 2 2 2 Thioesterase domain AMP-binding_C PF13193.6 KEZ35942.1 - 2.8e-13 50.6 0.3 2.8e-13 50.6 0.3 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ35942.1 - 1.3e-11 44.7 0.2 2.6e-11 43.7 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KEZ35942.1 - 0.0076 16.9 19.5 0.0076 16.9 19.5 4.1 1 1 2 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ35942.1 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FMN_dh PF01070.18 KEZ35943.1 - 1.8e-137 458.0 0.0 2.1e-137 457.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KEZ35943.1 - 6e-05 22.2 0.7 0.0002 20.5 0.6 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KEZ35943.1 - 0.00068 19.1 2.6 0.0013 18.2 2.6 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KEZ35943.1 - 0.001 18.3 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KEZ35943.1 - 0.082 12.4 0.1 0.16 11.4 0.1 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein SNF2_N PF00176.23 KEZ35944.1 - 2.2e-54 184.5 0.0 3.2e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ35944.1 - 1.3e-13 51.2 0.0 2.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ35944.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWIM PF04434.17 KEZ35944.1 - 0.0036 16.9 1.3 0.0069 16.0 1.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger SNF2_assoc PF08455.10 KEZ35944.1 - 0.0089 15.1 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated Zn_peptidase PF04228.13 KEZ35945.1 - 2.1e-06 27.4 3.2 0.0093 15.4 0.1 2.2 1 1 1 2 2 2 2 Putative neutral zinc metallopeptidase PMT_2 PF13231.6 KEZ35947.1 - 0.0001 22.5 8.0 0.0001 22.5 8.0 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 KEZ35947.1 - 1.4 8.4 15.2 0.2 11.2 11.1 1.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Rsm22 PF09243.10 KEZ35948.1 - 1.6e-72 244.1 0.0 1.9e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 KEZ35948.1 - 6e-06 26.9 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thioesterase PF00975.20 KEZ35949.1 - 1.4e-57 195.5 0.0 1.6e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KEZ35949.1 - 2.9e-11 44.4 6.2 3.7e-11 44.1 6.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ35949.1 - 8.3e-05 22.4 0.0 0.013 15.1 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ35949.1 - 0.0068 15.7 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 MFS_3 PF05977.13 KEZ35950.1 - 4.2e-48 164.0 29.2 4.9e-48 163.8 29.2 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KEZ35950.1 - 7.1e-25 87.7 42.3 5.1e-17 61.8 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD-oxidase_C PF02913.19 KEZ35951.1 - 1.1e-46 159.5 0.6 1.9e-46 158.8 0.6 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ35951.1 - 9.2e-37 125.9 5.7 2.4e-36 124.6 5.7 1.7 1 0 0 1 1 1 1 FAD binding domain Rhodanese PF00581.20 KEZ35952.1 - 1.8e-21 76.7 0.0 2.4e-13 50.5 0.0 3.2 2 1 0 2 2 2 2 Rhodanese-like domain ApbA PF02558.16 KEZ35952.1 - 2.2e-14 53.4 0.0 6.3e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEZ35952.1 - 2.3e-07 31.1 0.0 4.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_2 PF00890.24 KEZ35952.1 - 0.00011 21.4 1.0 0.00018 20.8 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ35952.1 - 0.029 13.6 3.3 0.052 12.8 3.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KEZ35952.1 - 0.047 13.0 2.5 0.065 12.5 2.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEZ35952.1 - 0.052 13.8 3.8 0.054 13.8 0.2 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 KEZ35952.1 - 0.081 13.4 0.0 0.081 13.4 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KEZ35952.1 - 0.32 11.6 0.1 0.32 11.6 0.1 2.4 2 1 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 KEZ35952.1 - 0.47 10.7 7.4 0.29 11.4 3.1 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KEZ35952.1 - 0.67 9.8 2.0 1.6 8.6 2.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KEZ35952.1 - 2.3 7.4 6.8 0.87 8.8 3.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 KEZ35953.1 - 2.3e-44 151.3 0.0 5e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEZ35953.1 - 6.5e-10 39.3 3.7 0.00031 20.7 0.2 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 KEZ35953.1 - 9.3e-07 29.3 0.0 0.00069 20.1 0.1 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 KEZ35953.1 - 2.6e-05 23.8 0.0 0.059 12.8 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KEZ35953.1 - 0.016 14.0 0.1 6.9 5.3 0.1 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 KEZ35953.1 - 0.04 14.1 0.4 3 8.2 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KEZ35953.1 - 0.11 12.9 3.1 0.1 13.0 0.7 2.1 2 0 0 2 2 2 0 AAA ATPase domain BPD_transp_1 PF00528.22 KEZ35954.1 - 4.4e-26 91.8 15.1 5.5e-26 91.4 15.1 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 KEZ35955.1 - 5.4e-18 65.1 0.6 8.3e-18 64.5 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KEZ35955.1 - 4.3e-12 46.2 4.1 4.3e-12 46.2 4.1 3.1 1 1 2 3 3 3 1 Binding-protein-dependent transport system inner membrane component Acyl-CoA_dh_2 PF08028.11 KEZ35956.1 - 2.9e-17 63.2 3.7 4.7e-17 62.5 3.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KEZ35956.1 - 3.2e-14 53.4 1.4 4.9e-14 52.8 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ35956.1 - 1.5e-08 34.8 0.0 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 KEZ35956.1 - 0.11 12.2 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal HTH_1 PF00126.27 KEZ35957.1 - 4.8e-19 68.0 0.1 2.1e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 KEZ35957.1 - 1.1e-16 60.9 10.6 1.1e-16 60.9 10.6 1.4 2 0 0 2 2 2 1 LysR substrate binding domain P22_Cro PF14549.6 KEZ35957.1 - 0.02 14.8 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro HTH_30 PF13556.6 KEZ35957.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 KEZ35957.1 - 0.037 13.9 0.3 0.068 13.0 0.3 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 KEZ35957.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EAL PF00563.20 KEZ35958.1 - 6e-48 163.4 0.0 8.4e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 EAL domain GAF_2 PF13185.6 KEZ35958.1 - 2.2e-10 41.0 1.3 1.3e-09 38.5 1.5 2.1 2 0 0 2 2 2 1 GAF domain SBP_bac_3 PF00497.20 KEZ35960.1 - 4.7e-47 160.3 0.0 5.6e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KEZ35960.1 - 0.002 18.3 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF2016 PF09436.10 KEZ35960.1 - 0.078 12.8 0.2 6.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) PknG_TPR PF16918.5 KEZ35961.1 - 1.6e-60 204.6 12.9 2.5e-60 204.0 12.9 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat PknG_rubred PF16919.5 KEZ35961.1 - 3.3e-25 88.9 4.6 6.4e-25 87.9 4.6 1.4 1 0 0 1 1 1 1 Protein kinase G rubredoxin domain Pkinase PF00069.25 KEZ35961.1 - 7.5e-23 81.2 0.0 1.1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TPR_19 PF14559.6 KEZ35961.1 - 6.9e-13 48.9 8.2 2.4e-05 24.8 1.9 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 KEZ35961.1 - 8e-12 45.0 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_6 PF13174.6 KEZ35961.1 - 9.2e-06 26.0 5.3 4 8.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ35961.1 - 1.9e-05 25.2 4.4 1.9e-05 25.2 4.4 4.4 6 0 0 6 6 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KEZ35961.1 - 8.2e-05 22.4 4.8 0.01 15.6 0.5 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain DZR PF12773.7 KEZ35961.1 - 0.01 15.9 0.5 0.022 14.8 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon TPR_2 PF07719.17 KEZ35961.1 - 0.06 13.5 4.8 54 4.2 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat IBR PF01485.21 KEZ35961.1 - 0.15 12.3 0.1 18 5.6 0.0 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 KEZ35961.1 - 3.5 7.5 5.5 29 4.6 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.17 KEZ35961.1 - 4.8 7.2 8.6 16 5.5 2.6 2.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF2256 PF10013.9 KEZ35961.1 - 5.5 7.2 6.6 2.8 8.1 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) TPR_9 PF13371.6 KEZ35961.1 - 5.6 7.2 11.7 3.8 7.7 6.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat PP2C_2 PF13672.6 KEZ35962.1 - 7.4e-11 42.1 1.7 1.1e-10 41.6 1.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KEZ35962.1 - 7.9e-08 32.2 0.0 4.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C DZR PF12773.7 KEZ35962.1 - 0.00018 21.5 0.2 0.00034 20.6 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KEZ35962.1 - 0.0025 17.5 0.8 0.0025 17.5 0.8 1.6 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KEZ35962.1 - 0.0078 15.6 1.9 0.0078 15.6 1.9 1.9 3 0 0 3 3 3 1 zinc-ribbon domain DUF35_N PF12172.8 KEZ35962.1 - 0.015 15.2 4.2 0.034 14.0 4.2 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_15 PF17032.5 KEZ35962.1 - 0.073 13.8 0.1 0.11 13.3 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon family UPF0547 PF10571.9 KEZ35962.1 - 1.7 8.8 4.2 3.7 7.7 4.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Hexapep PF00132.24 KEZ35963.1 - 9.3e-15 53.7 11.9 1.2e-08 34.3 3.7 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ35963.1 - 6.7e-07 28.9 10.3 0.00018 21.2 4.1 3.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 KEZ35963.1 - 0.00049 20.4 0.0 0.00075 19.9 0.0 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Bactofilin PF04519.13 KEZ35963.1 - 0.044 14.1 2.7 0.068 13.5 1.7 1.9 2 0 0 2 2 2 0 Polymer-forming cytoskeletal PALP PF00291.25 KEZ35964.1 - 1.1e-69 235.1 2.2 1.2e-69 235.0 2.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MmgE_PrpD PF03972.14 KEZ35965.1 - 5.9e-55 186.6 7.3 3.3e-53 180.8 1.8 2.2 1 1 1 2 2 2 2 MmgE/PrpD family CoA_transf_3 PF02515.17 KEZ35966.1 - 4.6e-109 364.9 0.5 5.2e-109 364.7 0.5 1.0 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 KEZ35967.1 - 1.4e-47 161.7 4.7 1.4e-47 161.7 4.7 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ35967.1 - 2.4e-30 105.5 0.0 7e-30 104.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ35967.1 - 4.6e-25 87.6 0.0 8.7e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ35967.1 - 2e-21 76.7 2.1 3.9e-21 75.7 2.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NUDIX PF00293.28 KEZ35968.1 - 4.6e-20 72.0 1.5 5.2e-20 71.8 1.5 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEZ35968.1 - 1.7e-05 24.8 0.4 4.2e-05 23.5 0.4 1.6 1 1 0 1 1 1 1 NUDIX domain GDPD PF03009.17 KEZ35969.1 - 2.6e-49 168.3 0.0 3e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.25 KEZ35970.1 - 4.3e-31 108.2 0.0 6.3e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ35970.1 - 9.7e-20 70.9 0.0 1.3e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ35970.1 - 2.4e-08 34.2 1.2 2.4e-08 34.2 1.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family RskA PF10099.9 KEZ35970.1 - 0.00059 20.2 4.3 0.00059 20.2 4.3 2.5 2 1 0 2 2 2 1 Anti-sigma-K factor rskA RIO1 PF01163.22 KEZ35970.1 - 0.0031 17.1 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KEZ35970.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HicB PF05534.12 KEZ35971.1 - 4.1e-06 26.5 0.1 3.5e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 HicB family DUF1778 PF08681.11 KEZ35971.1 - 0.00034 20.5 0.2 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1778) HATPase_c_2 PF13581.6 KEZ35971.1 - 0.02 14.9 0.4 0.026 14.5 0.4 1.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Arc PF03869.14 KEZ35971.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Arc-like DNA binding domain RHH_1 PF01402.21 KEZ35971.1 - 0.059 13.3 1.0 0.19 11.7 0.0 2.3 2 1 0 2 2 2 0 Ribbon-helix-helix protein, copG family RHH_5 PF07878.11 KEZ35971.1 - 0.067 13.1 2.0 0.16 11.9 0.1 2.5 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Apolipoprotein PF01442.18 KEZ35971.1 - 0.078 12.8 2.7 0.18 11.6 1.5 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HicB_lk_antitox PF15919.5 KEZ35971.1 - 0.14 12.2 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system DUF4097 PF13349.6 KEZ35972.1 - 5.3e-12 45.6 0.3 2.7e-11 43.3 0.3 1.9 1 1 0 1 1 1 1 Putative adhesin DUF945 PF06097.11 KEZ35972.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) PCMT PF01135.19 KEZ35973.1 - 9.3e-29 100.7 0.0 1.4e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KEZ35973.1 - 4.1e-07 30.6 0.0 7.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KEZ35973.1 - 4.9e-06 25.8 0.0 7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KEZ35973.1 - 0.00023 21.0 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ35973.1 - 0.0013 19.3 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ35973.1 - 0.0032 17.0 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 KEZ35973.1 - 0.0086 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.20 KEZ35973.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KEZ35973.1 - 0.03 14.1 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ35973.1 - 0.11 13.3 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KEZ35973.1 - 0.2 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF4381 PF14316.6 KEZ35974.1 - 0.065 13.5 1.3 0.16 12.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Alkyl_sulf_dimr PF14863.6 KEZ35975.1 - 0.14 12.6 0.1 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation DDE_Tnp_IS66 PF03050.14 KEZ35977.1 - 0.00017 21.2 0.2 0.00021 20.9 0.2 1.2 1 0 0 1 1 1 1 Transposase IS66 family zf-NADH-PPase PF09297.11 KEZ35977.1 - 0.0054 16.4 1.3 0.011 15.4 1.3 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-ISL3 PF14690.6 KEZ35977.1 - 0.019 15.6 1.4 0.019 15.6 1.4 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 KEZ35977.1 - 0.064 13.4 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KEZ35977.1 - 0.12 12.2 3.9 0.21 11.5 3.2 1.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS ADPrib_exo_Tox PF03496.14 KEZ35978.1 - 4.2e-12 45.8 0.0 1.7e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 KEZ35978.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 1 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 KEZ35979.1 - 7.9e-09 35.1 0.0 3e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 KEZ35979.1 - 0.25 10.6 0.0 0.46 9.7 0.0 1.4 1 1 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DUF2724 PF10893.8 KEZ35980.1 - 0.065 13.1 0.2 0.08 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) PEGSRP PF07623.11 KEZ35981.1 - 0.36 10.7 1.1 0.36 10.7 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) HTH_OrfB_IS605 PF12323.8 KEZ35982.1 - 4.9e-10 38.7 1.8 1.9e-08 33.6 0.2 2.1 2 0 0 2 2 2 2 Helix-turn-helix domain Resolvase PF00239.21 KEZ35983.1 - 4.5e-06 26.8 0.3 5.4e-06 26.6 0.3 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain MerR_1 PF13411.6 KEZ35984.1 - 3.3e-11 43.1 0.0 5.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 KEZ35984.1 - 4e-08 33.7 4.1 1.9e-07 31.5 4.1 2.1 1 1 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 KEZ35984.1 - 1.3e-06 28.1 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 MerR family regulatory protein DUF3106 PF11304.8 KEZ35984.1 - 0.042 14.3 0.3 0.058 13.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) MerR_1 PF13411.6 KEZ35985.1 - 2.7e-17 62.6 0.0 4.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ35985.1 - 3.4e-14 52.3 0.6 7e-14 51.3 0.6 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KEZ35985.1 - 4.3e-10 40.0 2.4 2.7e-09 37.4 2.5 2.3 2 1 0 2 2 2 1 MerR, DNA binding DHR10 PF18595.1 KEZ35985.1 - 0.027 14.5 0.6 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HTH_17 PF12728.7 KEZ35985.1 - 0.045 13.9 0.2 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KEZ35985.1 - 0.097 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyoxalase_4 PF13669.6 KEZ35986.1 - 6.7e-22 77.8 0.0 7.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KEZ35986.1 - 3.2e-10 40.4 0.1 3.5e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KEZ35986.1 - 1.5e-09 38.1 0.0 1.3e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Lipoprotein_21 PF14041.6 KEZ35987.1 - 4e-28 97.4 0.0 6e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 LppP/LprE lipoprotein ADC PF06314.11 KEZ35988.1 - 3.2e-10 40.0 1.1 4.9e-10 39.4 1.1 1.5 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Aldedh PF00171.22 KEZ35989.1 - 1.7e-125 419.2 0.7 2e-125 418.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family E1_dh PF00676.20 KEZ35990.1 - 8.6e-66 221.9 0.0 1.1e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KEZ35990.1 - 0.00078 19.3 1.3 0.016 15.0 1.3 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KEZ35990.1 - 0.081 12.1 0.0 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase UPF0060 PF02694.15 KEZ35991.1 - 4.1e-42 142.8 8.1 4.6e-42 142.6 8.1 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family DUF2157 PF09925.9 KEZ35991.1 - 0.088 12.6 9.6 4.7 7.0 9.6 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF543 PF04418.12 KEZ35991.1 - 1 9.4 6.3 16 5.6 6.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF543) MerR_2 PF13591.6 KEZ35993.1 - 3.5e-12 46.0 0.0 4.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein DUF3701 PF12482.8 KEZ35993.1 - 0.087 12.9 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Phage integrase protein AAA_2 PF07724.14 KEZ35994.1 - 1.2e-39 136.1 0.0 4.8e-38 130.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KEZ35994.1 - 4.6e-31 106.8 0.8 3.1e-30 104.2 0.0 2.3 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KEZ35994.1 - 4e-23 81.3 0.2 1.6e-22 79.4 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KEZ35994.1 - 9.4e-23 80.1 3.3 3.3e-10 39.9 0.4 3.4 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 KEZ35994.1 - 1.9e-17 63.9 0.0 9e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEZ35994.1 - 8.7e-16 58.2 0.0 8.9e-11 41.9 0.0 3.8 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ35994.1 - 1.2e-10 42.1 16.0 5.7e-06 26.8 0.2 5.2 3 3 0 4 4 3 2 AAA ATPase domain TniB PF05621.11 KEZ35994.1 - 1.3e-07 31.2 0.0 4.1e-05 23.1 0.0 3.2 2 1 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 KEZ35994.1 - 1.9e-06 28.2 1.8 0.11 12.7 0.0 4.6 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 KEZ35994.1 - 2.4e-05 24.1 0.0 0.0074 16.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KEZ35994.1 - 4.2e-05 23.5 0.0 0.097 12.6 0.0 3.1 2 1 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.17 KEZ35994.1 - 7.8e-05 22.5 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KEZ35994.1 - 0.00019 21.2 0.0 0.047 13.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KEZ35994.1 - 0.00028 20.9 0.1 0.52 10.2 0.0 3.5 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KEZ35994.1 - 0.00035 20.6 0.0 0.72 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KEZ35994.1 - 0.0004 20.4 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KEZ35994.1 - 0.00044 20.8 0.0 1.8 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KEZ35994.1 - 0.0017 17.8 0.2 0.89 8.9 0.2 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KEZ35994.1 - 0.0017 17.7 1.7 0.17 11.1 0.0 3.3 4 0 0 4 4 3 1 Zeta toxin Roc PF08477.13 KEZ35994.1 - 0.0021 18.3 0.0 0.86 9.8 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 KEZ35994.1 - 0.0047 16.7 0.2 4.3 7.1 0.0 3.7 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 KEZ35994.1 - 0.0058 17.2 0.1 0.43 11.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KEZ35994.1 - 0.0065 16.8 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DNA_pol3_delta2 PF13177.6 KEZ35994.1 - 0.018 14.8 0.0 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 KEZ35994.1 - 0.041 13.7 0.0 25 4.7 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KEZ35994.1 - 0.046 13.2 0.0 6.2 6.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KEZ35994.1 - 0.1 12.8 7.8 5.6 7.2 0.0 4.3 4 2 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 KEZ35994.1 - 0.14 12.1 0.0 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Se-cys_synth_N PF12390.8 KEZ35994.1 - 0.18 12.0 5.8 0.33 11.2 0.3 4.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal CorA PF01544.18 KEZ35994.1 - 5.3 6.3 6.7 2.9 7.1 4.1 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Acetyltransf_7 PF13508.7 KEZ35995.1 - 6.9e-06 26.4 0.0 1.3e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ35995.1 - 3.2e-05 23.9 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ35995.1 - 0.0003 21.0 0.0 0.0004 20.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family SIR2 PF02146.17 KEZ35996.1 - 8.8e-37 126.7 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family HupF_HypC PF01455.18 KEZ35997.1 - 4.1e-06 26.9 0.3 7.9e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 HupF/HypC family CopC PF04234.12 KEZ35999.1 - 9.7e-23 81.0 0.1 9.7e-23 81.0 0.1 1.8 2 0 0 2 2 2 1 CopC domain Caa3_CtaG PF09678.10 KEZ36000.1 - 6.8e-77 258.1 28.4 6.8e-77 258.1 28.4 3.6 4 1 1 5 5 5 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) CopD PF05425.13 KEZ36000.1 - 1.3e-14 54.4 10.2 1.3e-14 54.4 10.2 6.7 4 3 4 8 8 8 1 Copper resistance protein D E1-E2_ATPase PF00122.20 KEZ36001.1 - 8.9e-41 139.4 0.6 8.9e-41 139.4 0.6 3.7 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ36001.1 - 9.4e-17 62.0 1.9 1.6e-16 61.2 1.9 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ36001.1 - 0.0015 18.3 0.2 0.0023 17.7 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro2_C5 PF18565.1 KEZ36001.1 - 0.086 12.7 0.6 0.28 11.0 0.2 2.0 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 Cation_ATPase_C PF00689.21 KEZ36001.1 - 1.1 9.0 16.5 0.08 12.6 9.1 2.6 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus BacA PF02673.18 KEZ36002.1 - 4.5e-80 269.0 1.3 5.2e-80 268.8 1.3 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA MerC PF03203.14 KEZ36002.1 - 2.7 8.5 5.8 0.57 10.7 1.3 2.2 2 1 0 2 2 2 0 MerC mercury resistance protein HTH_18 PF12833.7 KEZ36003.1 - 1.8e-22 79.4 0.9 3.9e-22 78.3 0.9 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding_2 PF14525.6 KEZ36003.1 - 4.6e-17 62.2 0.1 4.6e-17 62.2 0.1 2.0 2 0 0 2 2 2 1 AraC-binding-like domain HTH_AraC PF00165.23 KEZ36003.1 - 4.4e-10 39.4 0.2 2.1e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 KEZ36003.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_7 PF12973.7 KEZ36004.1 - 5e-08 32.8 0.1 6.4e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KEZ36004.1 - 0.00018 21.2 0.4 0.00031 20.4 0.4 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEZ36004.1 - 0.072 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain HTH_30 PF13556.6 KEZ36005.1 - 5.6e-24 83.7 0.9 1.4e-23 82.4 0.9 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 KEZ36005.1 - 9.7e-07 28.8 2.0 0.0029 17.7 0.0 3.9 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.6 KEZ36005.1 - 0.00088 19.0 0.2 0.0059 16.4 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_8 PF02954.19 KEZ36005.1 - 0.0072 16.1 0.3 0.026 14.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family MFS_1 PF07690.16 KEZ36006.1 - 1.2e-27 96.8 53.2 1.7e-18 66.7 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ36006.1 - 1.8e-27 96.3 27.5 5.4e-18 65.1 11.0 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter HpcH_HpaI PF03328.14 KEZ36007.1 - 7.7e-49 165.8 0.2 7.7e-49 165.8 0.2 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEZ36007.1 - 5.9e-11 42.1 0.1 2.1e-06 27.2 0.0 2.3 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.18 KEZ36007.1 - 0.00044 19.4 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Lipase_GDSL_2 PF13472.6 KEZ36007.1 - 0.09 13.2 0.3 0.68 10.3 0.0 2.4 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family HpcH_HpaI PF03328.14 KEZ36008.1 - 1.3e-28 99.7 0.0 3e-28 98.5 0.0 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEZ36008.1 - 0.067 12.3 0.0 6.6 5.8 0.0 2.1 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold Se-cys_synth_N PF12390.8 KEZ36008.1 - 4.4 7.6 6.1 26 5.2 0.3 3.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Aminotran_1_2 PF00155.21 KEZ36009.1 - 2.5e-35 122.3 0.0 3.1e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KEZ36009.1 - 9e-08 31.3 0.0 1.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KEZ36009.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KEZ36009.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.28 KEZ36009.1 - 0.045 12.4 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme DUF4051 PF13260.6 KEZ36009.1 - 0.082 12.7 0.4 0.2 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) AHSA1 PF08327.11 KEZ36010.1 - 0.0067 16.6 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein HTH_20 PF12840.7 KEZ36011.1 - 4.4e-14 52.3 2.8 4.4e-14 52.3 2.8 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ36011.1 - 5.2e-07 29.5 1.9 1.3e-06 28.2 1.9 1.8 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KEZ36011.1 - 8.8e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 KEZ36011.1 - 0.00016 21.5 0.1 0.00027 20.7 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 KEZ36011.1 - 0.00032 20.2 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KEZ36011.1 - 0.00057 19.8 2.0 0.0029 17.5 0.1 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_1 PF00126.27 KEZ36011.1 - 0.002 18.1 1.9 0.0055 16.6 1.9 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LexA_DNA_bind PF01726.16 KEZ36011.1 - 0.0067 16.2 0.5 0.017 14.9 0.1 1.8 2 0 0 2 2 2 1 LexA DNA binding domain HTH_29 PF13551.6 KEZ36011.1 - 0.013 15.5 1.1 0.03 14.4 1.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 KEZ36011.1 - 0.014 15.2 1.3 0.03 14.1 1.3 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain MOFRL PF05161.13 KEZ36011.1 - 0.033 14.4 3.8 0.045 13.9 2.0 2.1 1 1 1 2 2 2 0 MOFRL family HTH_28 PF13518.6 KEZ36011.1 - 0.049 13.8 0.5 0.12 12.5 0.5 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_12 PF08461.10 KEZ36011.1 - 0.09 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF2383 PF09537.10 KEZ36011.1 - 0.099 13.0 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) MarR PF01047.22 KEZ36011.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 MarR family FaeA PF04703.12 KEZ36011.1 - 0.17 12.3 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 FaeA-like protein Collagen PF01391.18 KEZ36011.1 - 0.31 10.8 6.8 0.57 10.0 6.8 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DprA_WH PF17782.1 KEZ36011.1 - 0.85 9.8 6.4 0.23 11.6 2.5 2.1 2 0 0 2 2 2 0 DprA winged helix domain FAD_binding_9 PF08021.11 KEZ36012.1 - 8.5e-33 113.1 0.0 1.3e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 KEZ36012.1 - 8.1e-32 110.2 1.9 1.2e-31 109.7 1.9 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein PknG_TPR PF16918.5 KEZ36013.1 - 1.9e-44 151.8 13.9 2.9e-44 151.2 13.9 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat Pkinase PF00069.25 KEZ36013.1 - 7.5e-27 94.3 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36013.1 - 1.9e-11 43.8 0.0 2.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PknG_rubred PF16919.5 KEZ36013.1 - 9.7e-10 38.8 0.9 2.2e-09 37.6 0.9 1.5 1 0 0 1 1 1 1 Protein kinase G rubredoxin domain TPR_16 PF13432.6 KEZ36013.1 - 5.7e-05 23.7 5.3 5.7e-05 23.7 5.3 4.8 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ36013.1 - 0.00028 21.3 12.0 0.0037 17.7 0.2 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat RIO1 PF01163.22 KEZ36013.1 - 0.0094 15.6 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family TPR_20 PF14561.6 KEZ36013.1 - 0.074 13.4 0.3 4.4 7.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat WaaY PF06176.11 KEZ36013.1 - 0.19 11.3 0.0 0.48 10.0 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) TPR_14 PF13428.6 KEZ36013.1 - 1.6 9.7 23.5 0.2 12.6 2.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat SBP_bac_3 PF00497.20 KEZ36016.1 - 3e-42 144.6 0.0 3.6e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KEZ36016.1 - 0.00054 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF2148 PF09918.9 KEZ36016.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) DEC-1_N PF04625.13 KEZ36016.1 - 1 8.3 3.3 1.8 7.5 3.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4131 PF13567.6 KEZ36017.1 - 0.66 9.6 4.7 0.31 10.7 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Hydrolase_4 PF12146.8 KEZ36019.1 - 8.4e-07 28.5 0.9 0.26 10.5 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEZ36019.1 - 0.011 15.9 0.1 0.027 14.6 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Sod_Fe_C PF02777.18 KEZ36020.1 - 1e-32 112.3 0.3 1.5e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEZ36020.1 - 1.2e-29 102.6 0.1 2e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ferritin PF00210.24 KEZ36021.1 - 1.2e-35 122.5 0.3 1.6e-35 122.1 0.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain AIM24 PF01987.17 KEZ36022.1 - 7.5e-28 97.7 1.4 9.6e-28 97.4 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF5134 PF17197.4 KEZ36023.1 - 5.5e-21 75.0 22.3 5.5e-21 75.0 22.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5134) PMP22_Claudin PF00822.20 KEZ36023.1 - 0.33 10.8 4.5 0.81 9.5 0.1 2.5 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family EamA PF00892.20 KEZ36023.1 - 2.4 8.3 13.7 0.61 10.3 1.2 2.5 2 1 0 2 2 2 0 EamA-like transporter family Aldedh PF00171.22 KEZ36025.1 - 4.8e-90 302.3 0.0 5.8e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 KEZ36026.1 - 2.1e-20 73.5 0.0 3.3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase DUF742 PF05331.11 KEZ36027.1 - 3.8e-28 97.6 3.8 4.3e-28 97.4 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Robl_LC7 PF03259.17 KEZ36028.1 - 1.9e-19 69.2 0.2 2.5e-19 68.8 0.2 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain NIT PF08376.10 KEZ36029.1 - 7.9e-40 137.8 12.7 7.9e-40 137.8 12.7 2.2 2 0 0 2 2 2 1 Nitrate and nitrite sensing HAMP PF00672.25 KEZ36029.1 - 4.7e-09 36.5 0.8 4.7e-09 36.5 0.8 2.5 2 0 0 2 2 2 1 HAMP domain HATPase_c PF02518.26 KEZ36029.1 - 0.00012 22.5 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peripla_BP_6 PF13458.6 KEZ36030.1 - 3.3e-36 125.6 12.0 4.8e-36 125.1 12.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KEZ36030.1 - 1.4e-09 37.6 0.0 3.6e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KEZ36030.1 - 1.2e-05 24.4 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain ATPgrasp_N PF18130.1 KEZ36030.1 - 0.1 13.2 0.0 0.36 11.4 0.0 2.0 1 0 0 1 1 1 0 ATP-grasp N-terminal domain DUF222 PF02720.17 KEZ36032.1 - 9.1e-80 268.3 19.6 1.1e-79 268.1 19.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 KEZ36032.1 - 4.9e-05 23.4 7.0 8.5e-05 22.6 7.0 1.3 1 0 0 1 1 1 1 HNH endonuclease Cys_Met_Meta_PP PF01053.20 KEZ36033.1 - 8.6e-142 472.2 0.0 9.7e-142 472.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ36033.1 - 2.9e-05 23.5 0.1 5.3e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEZ36033.1 - 0.00041 19.4 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 KEZ36033.1 - 0.033 13.0 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Abhydrolase_1 PF00561.20 KEZ36034.1 - 4.2e-23 82.3 0.0 5.3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KEZ36034.1 - 0.0012 18.6 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KEZ36034.1 - 0.002 17.5 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 HTH_6 PF01418.17 KEZ36035.1 - 4.2e-18 65.1 0.0 7.2e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 KEZ36035.1 - 4.8e-15 55.6 0.0 6.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KEZ36035.1 - 3.9e-10 39.9 0.2 2.5e-06 27.5 0.1 2.6 1 1 1 2 2 2 2 SIS domain HTH_IclR PF09339.10 KEZ36035.1 - 0.029 14.2 0.4 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain ADH_zinc_N PF00107.26 KEZ36035.1 - 0.07 13.1 0.7 0.77 9.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HTH_11 PF08279.12 KEZ36035.1 - 0.081 12.9 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 HTH domain HTH_Crp_2 PF13545.6 KEZ36035.1 - 0.15 12.1 0.3 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain ABC_tran PF00005.27 KEZ36036.1 - 1.5e-32 112.9 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 KEZ36036.1 - 1.6e-10 41.7 0.1 5.9e-10 39.8 0.1 2.1 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 KEZ36036.1 - 1.6e-07 31.4 0.1 0.019 14.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 KEZ36036.1 - 2e-05 24.7 0.5 7.9e-05 22.8 0.5 2.1 1 1 0 1 1 1 1 TOBE domain AAA_16 PF13191.6 KEZ36036.1 - 0.00013 22.4 0.1 0.00022 21.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEZ36036.1 - 0.00035 20.6 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CysA_C_terminal PF17850.1 KEZ36036.1 - 0.00057 20.4 4.0 0.0016 19.0 0.1 3.4 4 0 0 4 4 3 1 CysA C-terminal regulatory domain Mg_chelatase PF01078.21 KEZ36036.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KEZ36036.1 - 0.0031 17.8 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KEZ36036.1 - 0.0035 17.3 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KEZ36036.1 - 0.0039 17.1 0.0 0.0087 16.0 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEZ36036.1 - 0.0045 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KEZ36036.1 - 0.0055 16.6 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KEZ36036.1 - 0.0061 17.0 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KEZ36036.1 - 0.0077 16.7 0.0 0.012 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KEZ36036.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KEZ36036.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KEZ36036.1 - 0.06 12.8 0.0 2.1 7.7 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KEZ36036.1 - 0.066 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KEZ36036.1 - 0.078 13.2 0.2 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEZ36036.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TOBE PF03459.17 KEZ36036.1 - 0.18 12.1 1.1 0.78 10.1 0.7 2.3 2 1 0 2 2 1 0 TOBE domain AAA_14 PF13173.6 KEZ36036.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEZ36036.1 - 0.27 10.4 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 KEZ36036.1 - 0.28 10.9 0.1 0.49 10.1 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SBP_bac_8 PF13416.6 KEZ36037.1 - 2.7e-30 106.1 1.4 4.1e-30 105.6 1.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KEZ36037.1 - 1.1e-26 94.6 4.3 1.7e-26 93.9 4.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Y_phosphatase3 PF13350.6 KEZ36038.1 - 2.3e-53 181.5 0.0 2.6e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KEZ36038.1 - 0.00017 21.2 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEZ36038.1 - 0.0015 18.2 0.0 0.0019 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase YAcAr PF10686.9 KEZ36038.1 - 0.02 14.8 0.4 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Myotub-related PF06602.14 KEZ36038.1 - 0.33 9.8 0.0 0.47 9.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Metallophos PF00149.28 KEZ36039.1 - 1.6e-14 54.9 0.0 3e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ36039.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BPD_transp_1 PF00528.22 KEZ36040.1 - 3.9e-15 56.1 14.5 3.9e-15 56.1 14.5 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KEZ36041.1 - 1.9e-14 53.8 13.9 1.9e-14 53.8 13.9 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component McrBC PF10117.9 KEZ36042.1 - 6.9e-41 140.4 0.0 8.1e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 McrBC 5-methylcytosine restriction system component PDDEXK_7 PF04411.12 KEZ36042.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily AAA_5 PF07728.14 KEZ36043.1 - 1.4e-17 63.9 0.0 2.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KEZ36043.1 - 2e-06 28.2 0.0 5.8e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ36043.1 - 0.00016 22.1 0.6 0.0018 18.7 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ36043.1 - 0.00076 19.8 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEZ36043.1 - 0.0023 17.5 0.0 0.033 13.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KEZ36043.1 - 0.0025 17.2 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KEZ36043.1 - 0.0033 17.4 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 KEZ36043.1 - 0.0036 16.8 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 KEZ36043.1 - 0.0078 16.0 0.0 0.021 14.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 KEZ36043.1 - 0.0084 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEZ36043.1 - 0.011 15.5 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KEZ36043.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KEZ36043.1 - 0.018 15.4 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KEZ36043.1 - 0.043 14.4 0.0 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEZ36043.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ36043.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ36043.1 - 0.27 10.7 0.0 0.48 9.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KEZ36044.1 - 5.3e-50 169.5 0.0 7.3e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KEZ36044.1 - 2.9e-07 30.8 0.1 1e-06 29.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain HEPN_AbiV PF18728.1 KEZ36045.1 - 0.0029 17.8 0.4 0.003 17.7 0.4 1.1 1 0 0 1 1 1 1 AbiV Peripla_BP_3 PF13377.6 KEZ36046.1 - 4.7e-24 85.6 0.7 5.1e-24 85.5 0.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 KEZ36046.1 - 0.00019 21.1 0.0 0.00042 20.0 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KEZ36046.1 - 0.011 15.1 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Herpes_US12 PF05363.12 KEZ36050.1 - 0.02 15.6 0.6 0.023 15.4 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus US12 family Nterm_IS4 PF13006.7 KEZ36050.1 - 0.056 13.6 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Nterm_IS4 PF13006.7 KEZ36053.1 - 4.1e-13 49.3 0.5 5e-13 49.1 0.5 1.0 1 0 0 1 1 1 1 Insertion element 4 transposase N-terminal CPSase_L_D2 PF02786.17 KEZ36055.1 - 7.7e-78 260.8 0.0 1.2e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEZ36055.1 - 4.6e-42 143.0 0.3 9.5e-42 142.0 0.3 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ36055.1 - 8.8e-36 122.3 0.0 2.5e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEZ36055.1 - 2.5e-16 59.2 1.5 2.5e-16 59.2 1.5 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KEZ36055.1 - 5e-10 39.3 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEZ36055.1 - 3.3e-08 33.3 0.0 6.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KEZ36055.1 - 1.6e-05 24.6 0.6 0.018 14.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KEZ36055.1 - 0.00014 22.0 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KEZ36055.1 - 0.042 13.0 0.4 1.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KEZ36055.1 - 0.29 11.8 1.5 4.3 8.1 0.1 3.1 3 1 1 4 4 4 0 HlyD family secretion protein Carboxyl_trans PF01039.22 KEZ36056.1 - 4.4e-142 474.2 0.0 5.6e-142 473.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AAA PF00004.29 KEZ36057.1 - 2.3e-10 41.0 0.0 0.00015 22.2 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ36057.1 - 5.2e-06 26.9 0.1 1.4e-05 25.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEZ36057.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KEZ36057.1 - 4.9e-05 23.1 0.1 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ36057.1 - 9.1e-05 22.7 0.0 0.00088 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ36057.1 - 0.0044 17.2 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KEZ36057.1 - 0.0063 16.8 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ36057.1 - 0.0065 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ36057.1 - 0.0078 16.6 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KEZ36057.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KEZ36057.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Rad17 PF03215.15 KEZ36057.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KEZ36057.1 - 0.031 13.8 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KEZ36057.1 - 0.043 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KEZ36057.1 - 0.044 14.3 0.0 0.093 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 KEZ36057.1 - 0.048 13.4 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KEZ36057.1 - 0.07 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 KEZ36057.1 - 0.073 13.6 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KEZ36057.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase RuvB_N PF05496.12 KEZ36057.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KEZ36057.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEZ36057.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KEZ36057.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 KEZ36057.1 - 0.19 12.2 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KEZ36057.1 - 0.27 10.7 0.0 0.44 10.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3710 PF12502.8 KEZ36058.1 - 4.8e-44 150.1 0.6 9.9e-44 149.1 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) TP_methylase PF00590.20 KEZ36059.1 - 2e-39 135.8 5.5 2.5e-39 135.4 5.5 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ntox10 PF15520.6 KEZ36059.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Novel toxin 10 CbiJ PF02571.14 KEZ36060.1 - 3.1e-64 216.7 0.0 3.5e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK TP_methylase PF00590.20 KEZ36061.1 - 2e-88 295.9 12.8 2.9e-48 164.7 0.7 2.0 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 KEZ36061.1 - 0.013 15.9 0.0 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 Radical SAM superfamily CbiC PF02570.15 KEZ36062.1 - 3.5e-71 238.9 0.5 3.9e-71 238.8 0.5 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase NIR_SIR_ferr PF03460.17 KEZ36063.1 - 9e-23 79.9 0.7 2.6e-12 46.4 0.1 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain CobN-Mg_chel PF02514.16 KEZ36064.1 - 0 1333.8 0.0 0 1333.6 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Aldo_ket_red PF00248.21 KEZ36065.1 - 3.4e-71 239.9 0.0 4.4e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MerR_1 PF13411.6 KEZ36066.1 - 2.4e-13 50.0 0.1 3.6e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ36066.1 - 2.1e-11 43.4 0.2 4.9e-11 42.2 0.2 1.7 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KEZ36066.1 - 0.00095 19.7 0.4 0.0015 19.0 0.4 1.3 1 0 0 1 1 1 1 MerR, DNA binding HTH_31 PF13560.6 KEZ36066.1 - 0.098 13.0 3.9 0.19 12.1 1.9 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 KEZ36066.1 - 0.21 11.7 3.2 0.36 11.0 0.1 2.7 3 1 1 4 4 4 0 Transcriptional regulator, AbiEi antitoxin DUF4614 PF15391.6 KEZ36067.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TPR_12 PF13424.6 KEZ36069.1 - 1.4e-22 79.7 39.5 2.8e-07 30.7 0.3 6.4 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ36069.1 - 1.5e-18 66.0 39.3 0.0014 18.4 0.4 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat AAA_31 PF13614.6 KEZ36069.1 - 1.1e-07 32.0 0.0 3.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KEZ36069.1 - 5.8e-07 29.6 0.0 2.5e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KEZ36069.1 - 1.8e-05 24.4 0.0 0.018 14.5 0.0 3.1 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase AAA_16 PF13191.6 KEZ36069.1 - 2.5e-05 24.7 2.1 0.00023 21.6 0.0 3.6 2 1 0 2 2 2 1 AAA ATPase domain VirC1 PF07015.11 KEZ36069.1 - 4e-05 23.0 0.3 0.00093 18.6 0.0 2.8 4 0 0 4 4 4 1 VirC1 protein NB-ARC PF00931.22 KEZ36069.1 - 0.00021 20.6 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain MipZ PF09140.11 KEZ36069.1 - 0.0043 16.4 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KEZ36069.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 KEZ36069.1 - 0.06 13.6 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 KEZ36069.1 - 0.067 12.7 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_5 PF07728.14 KEZ36069.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIR_2 PF13676.6 KEZ36071.1 - 1.4e-08 35.3 0.0 4.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.6 KEZ36072.1 - 2.4e-21 76.6 0.0 9.9e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 TIR domain TerD PF02342.18 KEZ36073.1 - 9.3e-68 227.4 0.0 1e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 TerD domain DSBA PF01323.20 KEZ36074.1 - 8.7e-10 38.7 0.0 1.1e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Shadoo PF14999.6 KEZ36074.1 - 0.51 10.4 6.6 19 5.4 4.0 2.5 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DUF1232 PF06803.12 KEZ36075.1 - 1.8e-08 34.1 7.8 1.8e-08 34.1 7.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1232) Trp_oprn_chp PF09534.10 KEZ36075.1 - 6.5 6.5 13.5 0.72 9.6 9.1 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Metallophos PF00149.28 KEZ36076.1 - 6.6e-16 59.4 0.0 1e-15 58.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ36076.1 - 5.4e-07 30.0 0.0 5.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain 4PPT_N PF17837.1 KEZ36077.1 - 1.4e-26 92.4 0.7 2.6e-26 91.5 0.7 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 KEZ36077.1 - 8.8e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_C24 PF03510.14 KEZ36078.1 - 0.021 15.3 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family Peptidase_C92 PF05708.12 KEZ36078.1 - 0.024 14.7 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PIN PF01850.21 KEZ36079.1 - 3.3e-11 43.8 0.0 3.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KEZ36079.1 - 0.12 13.2 1.1 0.25 12.1 1.1 1.6 1 1 0 1 1 1 0 PIN domain ParD PF09386.10 KEZ36080.1 - 0.0051 17.2 0.2 0.0054 17.1 0.2 1.2 1 0 0 1 1 1 1 Antitoxin ParD Amidinotransf PF02274.17 KEZ36081.1 - 1.5e-08 34.1 0.0 1.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase LAL_C2 PF18603.1 KEZ36082.1 - 7.7e-23 80.5 3.2 1.9e-22 79.2 3.2 1.7 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 KEZ36082.1 - 7.8e-13 48.3 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 KEZ36082.1 - 5.4e-05 23.7 0.1 0.00013 22.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 KEZ36082.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DUF456 PF04306.13 KEZ36083.1 - 4.8e-29 101.4 34.5 5.5e-29 101.2 34.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF456) WYL PF13280.6 KEZ36084.1 - 0.0047 17.0 0.0 0.0054 16.8 0.0 1.1 1 0 0 1 1 1 1 WYL domain Putative_PNPOx PF01243.20 KEZ36085.1 - 3.8e-08 33.4 0.0 7.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TetR_C_1 PF02909.17 KEZ36086.1 - 8e-13 48.4 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ36086.1 - 4.3e-07 29.6 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_32 PF13565.6 KEZ36087.1 - 0.0079 16.8 0.1 0.0083 16.7 0.1 1.1 1 0 0 1 1 1 1 Homeodomain-like domain THF_DHG_CYH_C PF02882.19 KEZ36089.1 - 2.4e-49 166.8 2.4 3.4e-49 166.2 2.4 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KEZ36089.1 - 3.1e-23 82.3 0.0 4.2e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GGDEF PF00990.21 KEZ36090.1 - 3.8e-43 147.0 0.0 4.8e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 KEZ36090.1 - 0.00029 21.1 0.8 0.00073 19.8 0.8 1.7 1 0 0 1 1 1 1 GGDEF-like domain DUF2946 PF11162.8 KEZ36090.1 - 1.1 9.9 8.7 0.15 12.7 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Aminotran_3 PF00202.21 KEZ36091.1 - 7.7e-118 393.7 0.0 9e-118 393.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Ribonuc_L-PSP PF01042.21 KEZ36092.1 - 0.00029 20.8 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP HD PF01966.22 KEZ36092.1 - 0.0028 17.9 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KEZ36092.1 - 0.082 12.6 0.5 0.11 12.2 0.6 1.3 1 1 0 1 1 1 0 HD domain Rhomboid PF01694.22 KEZ36093.1 - 1.5e-31 109.4 19.3 1.5e-31 109.4 19.3 1.8 2 0 0 2 2 2 1 Rhomboid family LZ_Tnp_IS66 PF13007.7 KEZ36094.1 - 5.8 7.8 7.5 41 5.0 7.4 2.5 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Response_reg PF00072.24 KEZ36095.1 - 2.7e-21 75.8 0.0 4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ36095.1 - 2.7e-20 71.6 0.2 4.7e-20 70.9 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ36095.1 - 3e-06 26.8 0.3 5.3e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KEZ36095.1 - 2.4e-05 24.0 0.2 5.2e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ36095.1 - 0.00054 19.5 0.3 0.001 18.5 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KEZ36095.1 - 0.0025 17.5 0.0 0.0074 16.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KEZ36095.1 - 0.0045 17.0 0.1 0.016 15.2 0.1 2.0 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4 PF04545.16 KEZ36095.1 - 0.0074 15.8 0.4 0.015 14.8 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 KEZ36095.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GAF_2 PF13185.6 KEZ36096.1 - 3.6e-31 108.3 8.4 3.8e-19 69.3 0.2 2.8 3 0 0 3 3 3 2 GAF domain GAF PF01590.26 KEZ36096.1 - 3.9e-22 79.3 0.1 1.4e-10 41.9 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KEZ36096.1 - 1.5e-16 60.9 0.0 8.3e-07 29.4 0.1 2.4 2 0 0 2 2 2 2 GAF domain HisKA_3 PF07730.13 KEZ36096.1 - 8.9e-13 48.6 4.5 8.9e-13 48.6 4.5 3.2 4 0 0 4 4 4 1 Histidine kinase HATPase_c_2 PF13581.6 KEZ36096.1 - 2.2e-05 24.4 0.1 5.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ36096.1 - 0.0002 21.9 0.1 0.007 16.9 0.0 2.8 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CodY PF06018.14 KEZ36096.1 - 0.023 14.2 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 CodY GAF-like domain CDO_I PF05995.12 KEZ36098.1 - 3.7e-20 71.9 0.1 6.5e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I Cupin_2 PF07883.11 KEZ36098.1 - 0.053 13.2 1.5 0.099 12.4 1.5 1.5 1 0 0 1 1 1 0 Cupin domain Rhodanese PF00581.20 KEZ36099.1 - 4.1e-10 40.1 0.0 5.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain SH3_9 PF14604.6 KEZ36099.1 - 0.038 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF3280 PF11684.8 KEZ36099.1 - 0.14 12.6 0.2 0.2 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) Whib PF02467.16 KEZ36100.1 - 9.8e-22 77.3 4.4 1.3e-21 76.9 4.4 1.2 1 0 0 1 1 1 1 Transcription factor WhiB TSC21 PF15217.6 KEZ36100.1 - 0.055 13.4 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 TSC21 family His_Phos_1 PF00300.22 KEZ36102.1 - 3.7e-11 43.1 0.1 2.5e-10 40.4 0.0 1.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Xan_ur_permease PF00860.20 KEZ36103.1 - 0.00052 18.8 3.0 0.00058 18.7 3.0 1.0 1 0 0 1 1 1 1 Permease family Claudin_2 PF13903.6 KEZ36103.1 - 0.0016 18.3 2.3 0.0016 18.3 2.3 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.9 KEZ36103.1 - 0.015 14.1 1.0 0.017 13.9 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2892 PF11127.8 KEZ36103.1 - 0.073 13.1 5.4 0.1 12.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Serinc PF03348.15 KEZ36103.1 - 0.095 11.6 0.6 0.11 11.4 0.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Phage_holin_3_6 PF07332.11 KEZ36103.1 - 0.26 11.4 7.5 0.3 11.1 7.5 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3040 PF11239.8 KEZ36103.1 - 1.7 9.0 7.1 2.6 8.4 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Glyco_transf_20 PF00982.21 KEZ36104.1 - 6.6e-104 348.2 0.0 8.1e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 GrpE PF01025.19 KEZ36105.1 - 0.0028 17.3 0.1 0.0031 17.2 0.1 1.0 1 0 0 1 1 1 1 GrpE Sec2p PF06428.11 KEZ36105.1 - 0.014 15.4 0.7 0.019 14.9 0.7 1.3 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2564 PF10819.8 KEZ36105.1 - 0.02 15.2 3.5 0.081 13.3 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2564) Baculo_PEP_C PF04513.12 KEZ36105.1 - 0.023 14.8 0.3 0.027 14.5 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KEZ36105.1 - 0.086 13.2 1.3 0.46 10.9 0.3 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IKKbetaNEMObind PF12179.8 KEZ36105.1 - 0.11 12.6 0.4 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain TraC_F_IV PF11130.8 KEZ36105.1 - 0.13 11.9 0.7 0.47 10.0 0.3 1.8 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer E1-N PF14463.6 KEZ36106.1 - 0.066 13.0 12.7 0.047 13.5 1.8 3.0 1 1 2 3 3 3 0 E1 N-terminal domain FtsK_SpoIIIE PF01580.18 KEZ36107.1 - 1.2e-17 64.1 0.0 3.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ36107.1 - 0.00064 20.1 0.5 0.0045 17.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ36107.1 - 0.023 15.0 0.0 0.061 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KEZ36107.1 - 0.023 13.6 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KEZ36107.1 - 0.024 14.5 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KEZ36107.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KEZ36107.1 - 0.083 12.5 4.9 1.9 8.0 3.2 3.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEZ36107.1 - 0.18 11.1 0.0 0.45 9.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KEZ36107.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Acid_phosphat_B PF03767.14 KEZ36108.1 - 0.0079 15.8 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) TrkA_N PF02254.18 KEZ36108.1 - 0.02 15.1 0.0 2.9 8.2 0.0 2.3 2 1 0 2 2 2 0 TrkA-N domain DUF4224 PF13986.6 KEZ36108.1 - 0.097 12.6 0.2 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) ABC2_membrane PF01061.24 KEZ36109.1 - 6.8e-35 120.4 16.1 9.3e-35 119.9 16.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ36109.1 - 1e-19 70.9 11.8 1e-19 70.9 11.8 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEZ36109.1 - 2.9e-05 23.5 13.5 2.9e-05 23.5 13.5 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein PetM PF08041.11 KEZ36109.1 - 0.023 14.3 1.7 0.093 12.3 1.7 2.1 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 CCB1 PF12046.8 KEZ36109.1 - 0.13 11.6 0.2 0.13 11.6 0.2 1.7 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B ABC_tran PF00005.27 KEZ36110.1 - 6.4e-16 59.1 0.0 1e-15 58.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ36110.1 - 8.8e-09 35.6 0.0 8.8e-09 35.6 0.0 2.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KEZ36110.1 - 5e-07 30.4 0.0 9.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) KdpD PF02702.17 KEZ36110.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain Resolvase PF00239.21 KEZ36111.1 - 1.9e-10 41.0 0.0 8.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Resolvase, N terminal domain TilS PF09179.11 KEZ36111.1 - 0.014 15.9 4.1 0.52 10.9 0.1 3.5 3 0 0 3 3 3 0 TilS substrate binding domain Recombinase PF07508.13 KEZ36111.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Recombinase Zn_ribbon_recom PF13408.6 KEZ36111.1 - 0.11 13.0 0.2 0.21 12.1 0.2 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain MM_CoA_mutase PF01642.22 KEZ36113.1 - 8.3e-140 466.7 0.2 1.6e-139 465.8 0.1 1.5 2 0 0 2 2 2 1 Methylmalonyl-CoA mutase MeaB PF03308.16 KEZ36113.1 - 4.4e-46 157.0 0.2 7.9e-46 156.2 0.2 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB B12-binding PF02310.19 KEZ36113.1 - 2.3e-11 43.8 1.3 8.7e-11 41.9 0.5 2.4 3 0 0 3 3 3 1 B12 binding domain cobW PF02492.19 KEZ36113.1 - 0.00019 21.1 0.0 0.00065 19.3 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KEZ36113.1 - 0.00069 20.0 1.9 0.023 15.1 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain SelB-wing_2 PF09106.11 KEZ36113.1 - 0.011 15.9 1.0 0.039 14.1 0.7 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF2188 PF09954.9 KEZ36113.1 - 0.033 14.3 1.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) AAA_18 PF13238.6 KEZ36113.1 - 0.12 13.0 0.7 0.51 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain MarR PF01047.22 KEZ36114.1 - 6.7e-12 45.1 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KEZ36114.1 - 1.4e-09 37.7 0.4 2.7e-09 36.8 0.4 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KEZ36114.1 - 1.9e-05 25.1 0.0 3.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 KEZ36114.1 - 0.0086 16.2 0.0 0.015 15.4 0.0 1.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain GntR PF00392.21 KEZ36114.1 - 0.012 15.3 0.0 0.034 13.8 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 KEZ36114.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Aminotran_5 PF00266.19 KEZ36115.1 - 3.5e-58 197.3 0.0 3e-50 171.2 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ36115.1 - 2.1e-10 40.4 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEZ36115.1 - 0.0031 16.9 0.3 0.0044 16.4 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KEZ36115.1 - 0.0039 16.0 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain tRNA_Me_trans PF03054.16 KEZ36116.1 - 7.6e-109 363.8 0.0 8.5e-109 363.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KEZ36116.1 - 0.0034 17.0 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) DUF1611_N PF17396.2 KEZ36116.1 - 0.018 15.3 0.1 8.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain NAD_synthase PF02540.17 KEZ36116.1 - 0.023 13.8 0.1 0.038 13.1 0.1 1.5 1 1 0 1 1 1 0 NAD synthase QueC PF06508.13 KEZ36116.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Meth_synt_2 PF01717.18 KEZ36117.1 - 6.1e-06 25.7 0.0 0.003 16.9 0.0 2.9 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Collagen PF01391.18 KEZ36117.1 - 8.6e-05 22.2 7.8 0.00018 21.2 7.8 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DNA_ligase_aden PF01653.18 KEZ36118.1 - 7.9e-120 399.7 0.0 1e-119 399.3 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 KEZ36118.1 - 7.9e-30 102.6 1.8 7.9e-30 102.6 1.8 1.9 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 KEZ36118.1 - 9.9e-21 73.6 0.4 4e-20 71.7 0.1 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KEZ36118.1 - 7.6e-16 58.5 0.9 3.3e-08 34.0 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 KEZ36118.1 - 1.1e-12 48.2 0.0 1.7e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 KEZ36118.1 - 1.9e-11 43.8 6.5 6.3e-11 42.1 6.5 2.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain HHH PF00633.23 KEZ36118.1 - 7.2e-08 31.9 0.8 1.2e-06 28.1 0.2 3.4 3 0 0 3 3 3 1 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 KEZ36118.1 - 2.2e-06 27.5 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HHH_8 PF14716.6 KEZ36118.1 - 0.066 13.6 0.2 0.63 10.5 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain TF_Zn_Ribbon PF08271.12 KEZ36118.1 - 0.16 11.5 1.9 0.28 10.7 1.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Bap31_Bap29_C PF18035.1 KEZ36118.1 - 0.25 11.4 0.7 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ACT PF01842.25 KEZ36119.1 - 5.6e-08 32.4 0.1 1.2e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KEZ36119.1 - 0.02 15.5 0.0 0.076 13.6 0.0 1.8 2 0 0 2 2 2 0 ACT domain Glu-tRNAGln PF02686.15 KEZ36120.1 - 9.9e-15 54.6 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Amidase PF01425.21 KEZ36121.1 - 1.6e-164 548.2 0.2 1.9e-164 548.0 0.2 1.0 1 0 0 1 1 1 1 Amidase UbiA PF01040.18 KEZ36122.1 - 0.0084 15.4 0.8 0.0085 15.4 0.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Promethin PF16015.5 KEZ36122.1 - 0.011 15.7 2.0 0.012 15.5 2.0 1.1 1 0 0 1 1 1 0 Promethin DUF4436 PF14494.6 KEZ36122.1 - 0.024 13.9 1.1 0.027 13.8 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF4131 PF13567.6 KEZ36122.1 - 0.035 13.7 1.9 0.04 13.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3040 PF11239.8 KEZ36122.1 - 0.14 12.4 5.5 0.17 12.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1129 PF06570.11 KEZ36122.1 - 0.24 10.8 1.9 0.28 10.6 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GatB_N PF02934.15 KEZ36123.1 - 6.7e-110 366.8 0.0 8.4e-110 366.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KEZ36123.1 - 3.3e-33 114.7 0.0 4.6e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 GatB domain Transpeptidase PF00905.22 KEZ36124.1 - 4.8e-46 157.4 0.0 7.5e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain MoCF_biosynth PF00994.24 KEZ36124.1 - 0.11 12.1 0.2 0.76 9.4 0.1 2.3 2 0 0 2 2 2 0 Probable molybdopterin binding domain DUF2749 PF10907.8 KEZ36124.1 - 0.11 12.6 0.9 0.62 10.3 0.9 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) TPP_enzyme_N PF02776.18 KEZ36126.1 - 3e-54 183.2 0.5 7.2e-54 182.0 0.5 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ36126.1 - 2.3e-51 173.1 0.2 6.3e-51 171.7 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KEZ36126.1 - 1.6e-46 157.8 0.4 1.1e-45 155.2 0.4 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 KEZ36126.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POR_N PF01855.19 KEZ36126.1 - 0.01 15.6 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ALS_ss_C PF10369.9 KEZ36127.1 - 1.1e-27 96.0 3.1 1.9e-27 95.2 0.4 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KEZ36127.1 - 2.2e-17 62.5 1.0 3.1e-17 62.0 0.1 1.7 2 1 0 2 2 2 1 ACT domain ACT_5 PF13710.6 KEZ36127.1 - 2.7e-16 59.2 0.1 6.2e-16 58.0 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KEZ36127.1 - 2.3e-06 28.1 0.9 4e-06 27.3 0.2 1.7 2 0 0 2 2 2 1 ACT domain THOC7 PF05615.13 KEZ36127.1 - 0.022 15.0 0.2 0.028 14.7 0.2 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 IlvN PF07991.12 KEZ36128.1 - 1.2e-68 229.9 0.1 1.5e-68 229.6 0.1 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KEZ36128.1 - 1.5e-65 219.8 0.0 2e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 KEZ36128.1 - 3.1e-06 26.7 0.0 5.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ36128.1 - 4e-06 27.3 0.0 9.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEZ36128.1 - 2.8e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KEZ36128.1 - 0.0024 18.0 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GFO_IDH_MocA PF01408.22 KEZ36128.1 - 0.032 15.1 0.0 0.054 14.3 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 KEZ36128.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_C PF03720.15 KEZ36128.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 KEZ36128.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KEZ36129.1 - 7.4e-62 207.9 0.1 3.4e-61 205.7 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEZ36129.1 - 1.1e-33 115.7 0.6 1.9e-33 114.9 0.6 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KEZ36129.1 - 2.1e-11 43.3 0.1 1.2e-10 40.9 0.1 2.4 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 KEZ36129.1 - 0.00015 21.4 0.0 0.00038 20.1 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KEZ36129.1 - 0.00019 21.6 0.5 0.00056 20.1 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KEZ36129.1 - 0.0037 17.6 0.4 0.014 15.8 0.0 2.1 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AdoHcyase_NAD PF00670.21 KEZ36129.1 - 0.0093 16.0 0.6 0.022 14.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KEZ36129.1 - 0.031 14.2 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT_4 PF13291.6 KEZ36129.1 - 0.049 14.2 0.0 1 10.0 0.0 3.1 3 0 0 3 3 3 0 ACT domain ThiF PF00899.21 KEZ36129.1 - 0.067 12.5 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 KEZ36129.1 - 0.1 12.9 3.6 0.34 11.2 0.1 3.0 3 0 0 3 3 3 0 TrkA-N domain Septum_form PF13845.6 KEZ36130.1 - 6e-10 39.0 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Septum formation HMGL-like PF00682.19 KEZ36131.1 - 6.1e-74 248.9 0.0 1.3e-73 247.8 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KEZ36131.1 - 9.5e-31 106.4 0.2 1.6e-30 105.7 0.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF1059 PF06348.11 KEZ36132.1 - 1.2e-22 79.9 0.6 1.7e-22 79.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) EAL PF00563.20 KEZ36133.1 - 6.7e-41 140.4 0.0 9.7e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 EAL domain CBS PF00571.28 KEZ36133.1 - 0.00038 20.8 0.5 0.001 19.4 0.1 2.0 2 0 0 2 2 2 1 CBS domain Prok-JAB PF14464.6 KEZ36133.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Iso_dh PF00180.20 KEZ36134.1 - 3.6e-83 279.6 0.0 4.4e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_4 PF01063.19 KEZ36135.1 - 9.9e-48 162.9 0.0 1.2e-47 162.7 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV CBS PF00571.28 KEZ36136.1 - 2.9e-19 69.3 0.0 6e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 KEZ36137.1 - 5.5e-22 77.7 0.1 1.4e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 KEZ36137.1 - 2.8e-15 56.0 3.5 2.8e-15 56.0 3.5 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KEZ36137.1 - 0.00032 20.5 3.7 0.00055 19.8 0.3 2.7 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KEZ36137.1 - 0.0005 19.8 0.1 0.0015 18.3 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain GntR PF00392.21 KEZ36137.1 - 0.0068 16.0 2.3 0.0077 15.9 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 KEZ36137.1 - 0.0087 15.6 0.2 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 KEZ36137.1 - 0.058 13.1 1.3 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 MarR PF01047.22 KEZ36137.1 - 0.11 12.4 0.6 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 MarR family DUF1670 PF07900.11 KEZ36137.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) HMGL-like PF00682.19 KEZ36138.1 - 1.9e-42 145.6 1.2 2.8e-42 145.1 1.2 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KEZ36138.1 - 7.9e-31 106.7 0.2 4.3e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain HIPIP PF01355.17 KEZ36139.1 - 0.0015 18.8 1.5 0.0018 18.6 1.5 1.2 1 0 0 1 1 1 1 High potential iron-sulfur protein FAA_hydrolase PF01557.18 KEZ36140.1 - 6e-61 205.9 0.0 7.3e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 KEZ36140.1 - 2e-10 41.4 0.6 2e-10 41.4 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) DUF4573 PF15140.6 KEZ36141.1 - 0.034 13.9 0.2 0.044 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) DUF4211 PF13926.6 KEZ36141.1 - 0.2 11.7 0.1 0.26 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) HATPase_c PF02518.26 KEZ36142.1 - 1.4e-17 64.2 0.0 9.4e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ36142.1 - 2.2e-13 50.0 0.7 4.2e-13 49.1 0.7 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KEZ36142.1 - 0.0002 21.2 0.0 0.00064 19.6 0.0 1.9 2 0 0 2 2 2 1 GHKL domain Peptidase_U4 PF03419.13 KEZ36142.1 - 0.054 12.8 2.8 0.08 12.2 2.8 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA HATPase_c_2 PF13581.6 KEZ36142.1 - 0.089 12.7 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF4131 PF13567.6 KEZ36142.1 - 1.8 8.2 8.5 5.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 KEZ36143.1 - 1e-46 159.4 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36143.1 - 1.3e-29 103.3 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PASTA PF03793.19 KEZ36143.1 - 4.9e-10 39.1 0.1 0.00032 20.5 0.0 3.3 2 1 0 2 2 2 2 PASTA domain Pkinase_fungal PF17667.1 KEZ36143.1 - 8e-05 21.6 0.0 0.00018 20.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEZ36143.1 - 0.037 13.9 0.2 0.082 12.8 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 KEZ36143.1 - 0.051 13.7 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 KEZ36143.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IclR PF01614.18 KEZ36144.1 - 1.9e-15 56.8 1.3 8e-14 51.6 0.4 2.6 2 1 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KEZ36144.1 - 2.2e-08 33.8 5.2 2.2e-08 33.8 5.2 3.2 4 0 0 4 4 4 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KEZ36144.1 - 0.00055 19.8 14.5 0.00076 19.3 2.3 3.8 4 0 0 4 4 4 2 MarR family Autoind_bind PF03472.15 KEZ36144.1 - 0.028 13.9 0.6 0.55 9.7 0.1 2.7 2 1 0 2 2 2 0 Autoinducer binding domain Aconitase PF00330.20 KEZ36145.1 - 1.8e-156 521.8 0.0 2e-156 521.6 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 KEZ36145.1 - 0.032 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Aconitase_C PF00694.19 KEZ36146.1 - 2.4e-27 95.8 0.0 8.1e-27 94.1 0.0 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain Bac_DNA_binding PF00216.21 KEZ36147.1 - 9e-31 105.9 0.1 9.9e-31 105.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 KEZ36147.1 - 0.00025 21.1 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF2267 PF10025.9 KEZ36147.1 - 0.00058 20.1 0.6 0.00084 19.6 0.1 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) SSPI PF14098.6 KEZ36147.1 - 0.0047 17.0 0.1 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Small, acid-soluble spore protein I HU-CCDC81_bac_2 PF18175.1 KEZ36147.1 - 0.044 13.7 0.0 0.054 13.4 0.0 1.1 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 KEZ36147.1 - 0.051 13.7 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 PEP-utilisers_N PF05524.13 KEZ36147.1 - 0.053 13.7 0.2 0.075 13.2 0.2 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PP_kinase PF02503.17 KEZ36148.1 - 6.6e-76 254.4 0.2 1.3e-75 253.5 0.0 1.6 2 0 0 2 2 2 1 Polyphosphate kinase middle domain PP_kinase_C_1 PF17941.1 KEZ36148.1 - 2.8e-74 248.2 0.0 5.4e-74 247.3 0.0 1.5 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 KEZ36148.1 - 1.5e-57 193.8 0.0 1.7e-56 190.4 0.0 2.1 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase_N PF13089.6 KEZ36148.1 - 2.3e-34 117.9 0.0 4.8e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 KEZ36148.1 - 3.7e-08 33.3 0.0 9e-05 22.4 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain AcetylCoA_hyd_C PF13336.6 KEZ36148.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2120 PF09893.9 KEZ36148.1 - 0.12 12.4 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) EAL PF00563.20 KEZ36149.1 - 6.7e-59 199.3 0.0 1.2e-58 198.4 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KEZ36149.1 - 5.1e-41 140.1 0.0 7.6e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF4133 PF13571.6 KEZ36149.1 - 0.38 11.1 1.0 0.97 9.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) CofC PF01983.16 KEZ36150.1 - 0.00027 20.2 0.0 0.23 10.6 0.0 2.2 1 1 1 2 2 2 2 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 KEZ36150.1 - 0.0054 17.1 7.5 0.012 16.0 7.6 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 KEZ36150.1 - 0.018 14.9 0.2 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) NAD_Gly3P_dh_C PF07479.14 KEZ36152.1 - 1.1e-45 155.5 0.0 1.7e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KEZ36152.1 - 4e-45 153.6 0.1 5.5e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KEZ36152.1 - 7.2e-08 32.2 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KEZ36152.1 - 2.8e-07 31.0 0.5 1.7e-06 28.5 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEZ36152.1 - 0.005 17.0 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KEZ36152.1 - 0.027 14.3 1.4 0.046 13.6 0.1 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KEZ36152.1 - 0.061 12.3 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Pyr_redox PF00070.27 KEZ36152.1 - 0.11 13.0 0.5 0.91 10.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KEZ36152.1 - 0.27 11.1 3.9 0.16 11.9 1.0 2.2 2 1 0 2 2 2 0 Rossmann-like domain EPSP_synthase PF00275.20 KEZ36153.1 - 4.9e-63 213.2 0.1 5.7e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Phos_pyr_kin PF08543.12 KEZ36154.1 - 7e-78 261.4 0.0 7.8e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KEZ36154.1 - 1.2e-08 34.6 0.2 1.5e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 KEZ36154.1 - 0.0002 20.8 0.9 0.0012 18.3 0.9 2.0 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KEZ36154.1 - 0.027 13.9 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase AsnC_trans_reg PF01037.21 KEZ36155.1 - 2.3e-12 46.7 0.1 3.4e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 KEZ36155.1 - 0.019 15.0 0.4 0.036 14.1 0.4 1.3 1 0 0 1 1 1 0 NapD protein DUF3515 PF12028.8 KEZ36156.1 - 1.4e-15 57.4 0.8 1.8e-15 57.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3515) Dala_Dala_lig_C PF07478.13 KEZ36157.1 - 8.4e-67 224.7 0.0 1.1e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 KEZ36157.1 - 2e-29 102.1 0.0 3.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 KEZ36157.1 - 1.6e-11 44.1 0.0 5.8e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KEZ36157.1 - 0.00017 21.7 0.0 0.00061 19.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KEZ36157.1 - 0.0004 19.9 0.1 0.0044 16.5 0.1 2.0 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KEZ36157.1 - 0.0023 17.5 0.1 0.0097 15.5 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KEZ36157.1 - 0.025 13.9 0.0 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KEZ36157.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_L28 PF00830.19 KEZ36158.1 - 3e-24 85.0 2.4 3.6e-24 84.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal L28 family Tat PF00539.18 KEZ36158.1 - 0.018 15.2 0.6 0.022 14.9 0.1 1.4 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) DUF2180 PF09947.9 KEZ36158.1 - 0.12 12.4 1.7 0.22 11.5 1.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Helicase_C PF00271.31 KEZ36159.1 - 1.4e-19 70.5 0.0 2e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ36159.1 - 3.1e-17 62.9 0.0 7.7e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecG_wedge PF17191.4 KEZ36159.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 RecG wedge domain ResIII PF04851.15 KEZ36159.1 - 8.5e-09 35.6 0.0 1.6e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 KEZ36159.1 - 4.9e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AAA_30 PF13604.6 KEZ36159.1 - 0.0068 16.2 0.7 0.018 14.8 0.7 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEZ36159.1 - 0.037 13.6 0.8 0.14 11.7 0.8 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ36159.1 - 0.038 14.3 0.2 0.16 12.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain Cons_hypoth95 PF03602.15 KEZ36160.1 - 5.2e-49 166.4 0.0 5.9e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KEZ36160.1 - 1.1e-07 31.5 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KEZ36160.1 - 6.4e-06 26.0 0.0 7.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.15 KEZ36160.1 - 4.3e-05 23.3 0.1 0.2 11.3 0.4 2.1 1 1 1 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 KEZ36160.1 - 0.0002 22.0 0.0 0.00029 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEZ36160.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KEZ36160.1 - 0.047 13.4 0.1 0.21 11.3 0.1 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 RsmJ PF04378.13 KEZ36160.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ CTP_transf_like PF01467.26 KEZ36161.1 - 1.2e-18 67.7 0.0 1.5e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 KEZ36161.1 - 0.034 13.8 0.0 0.051 13.3 0.0 1.4 1 1 0 1 1 1 0 Citrate lyase ligase C-terminal domain Trans_reg_C PF00486.28 KEZ36161.1 - 0.04 14.0 0.0 4 7.6 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal YceD PF02620.17 KEZ36162.1 - 8.9e-28 96.8 0.1 1.2e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Ribosomal_L32p PF01783.23 KEZ36163.1 - 2.1e-22 79.1 5.1 2.3e-22 79.0 5.1 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family FA_synthesis PF02504.15 KEZ36164.1 - 3e-26 92.3 3.3 1.5e-22 80.1 0.3 3.0 3 0 0 3 3 3 3 Fatty acid synthesis protein PTA_PTB PF01515.19 KEZ36164.1 - 0.00026 20.4 0.5 0.0004 19.8 0.5 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase Ribonucleas_3_3 PF14622.6 KEZ36165.1 - 8.8e-37 126.1 0.0 1.2e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KEZ36165.1 - 3.5e-18 66.1 0.0 6.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KEZ36165.1 - 7.7e-13 49.0 0.3 1.2e-12 48.3 0.0 1.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif NPP1 PF05630.11 KEZ36166.1 - 0.011 15.8 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) H2TH PF06831.14 KEZ36167.1 - 2.2e-24 85.2 0.0 3.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KEZ36167.1 - 6.1e-11 43.0 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 KEZ36167.1 - 3.6e-06 26.7 3.6 6.6e-06 25.9 3.6 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DUF2786 PF10979.8 KEZ36168.1 - 1.6e-11 43.9 2.0 3.5e-11 42.8 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) Acylphosphatase PF00708.18 KEZ36169.1 - 4.4e-18 65.5 0.0 5.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Prok_Ub PF14454.6 KEZ36169.1 - 0.034 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic Ubiquitin WD40_alt PF14077.6 KEZ36170.1 - 0.0025 17.6 0.1 0.0041 17.0 0.1 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif Pox_A_type_inc PF04508.12 KEZ36170.1 - 0.0097 15.7 0.3 0.015 15.1 0.3 1.4 1 1 0 1 1 1 1 Viral A-type inclusion protein repeat DUF1192 PF06698.11 KEZ36170.1 - 0.026 14.6 0.3 0.026 14.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) GTP-bdg_M PF16360.5 KEZ36170.1 - 0.065 13.8 0.0 0.078 13.6 0.0 1.1 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Strep_SA_rep PF06696.11 KEZ36170.1 - 0.086 12.9 0.5 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 Streptococcal surface antigen repeat SMC_N PF02463.19 KEZ36171.1 - 3.6e-69 232.5 0.0 4.2e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEZ36171.1 - 5.5e-20 71.8 0.4 5.5e-20 71.8 0.4 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEZ36171.1 - 1.1e-16 61.5 0.4 2.6e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ36171.1 - 2.9e-14 54.0 0.2 2.9e-13 50.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KEZ36171.1 - 1.3e-10 41.6 0.0 5.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEZ36171.1 - 8.1e-06 25.5 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEZ36171.1 - 0.00055 20.5 0.1 0.21 12.1 0.1 3.1 2 0 0 2 2 2 1 ABC transporter DUF1043 PF06295.12 KEZ36171.1 - 0.18 11.8 0.4 0.46 10.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) AAA_22 PF13401.6 KEZ36171.1 - 0.77 10.0 5.8 7.2 6.9 0.1 4.1 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 KEZ36172.1 - 3.5e-72 242.2 1.3 4.4e-72 241.8 1.3 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KEZ36172.1 - 4.4e-12 46.0 0.1 8.7e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KEZ36172.1 - 3.3e-06 26.9 3.4 6e-06 26.1 3.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ36172.1 - 7e-06 26.5 0.5 1.4e-05 25.5 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KEZ36172.1 - 0.00014 21.9 0.0 0.00044 20.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KEZ36172.1 - 0.00041 19.7 0.0 0.00072 18.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 KEZ36172.1 - 0.00043 20.1 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 KEZ36172.1 - 0.005 16.5 0.0 0.031 13.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ36172.1 - 0.0055 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEZ36172.1 - 0.006 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ36172.1 - 0.02 15.3 0.1 0.044 14.2 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEZ36172.1 - 0.023 15.0 0.7 0.023 15.0 0.7 1.6 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 KEZ36172.1 - 0.027 14.1 0.2 0.2 11.3 0.2 2.0 1 1 1 2 2 2 0 Thymidylate kinase AAA_33 PF13671.6 KEZ36172.1 - 0.043 14.0 0.1 0.081 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEZ36172.1 - 0.045 13.7 0.2 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEZ36172.1 - 0.078 13.5 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEZ36172.1 - 0.087 12.7 0.9 0.13 12.2 0.1 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KEZ36172.1 - 0.09 12.7 1.3 0.48 10.3 0.9 2.1 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 KEZ36172.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KEZ36172.1 - 0.24 11.1 0.3 0.42 10.3 0.3 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KEZ36173.1 - 9.3e-66 221.2 0.0 1.4e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KEZ36173.1 - 4e-31 107.6 1.9 4e-31 107.6 0.3 1.9 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 KEZ36173.1 - 3.3e-20 72.1 0.1 8.2e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 KEZ36173.1 - 4.4e-06 26.8 0.0 3.3e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KEZ36173.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KEZ36173.1 - 0.011 15.4 0.6 0.045 13.3 0.6 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.6 KEZ36173.1 - 0.027 14.4 0.0 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.18 KEZ36173.1 - 0.091 12.1 0.1 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_24 PF13479.6 KEZ36173.1 - 0.093 12.4 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEZ36173.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Ribosomal_S16 PF00886.19 KEZ36174.1 - 3.5e-22 78.2 0.1 5.4e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 KH_4 PF13083.6 KEZ36175.1 - 1.4e-20 73.0 0.1 1.5e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 KEZ36175.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 KH domain KH_5 PF13184.6 KEZ36175.1 - 0.088 12.9 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 NusA-like KH domain RimM PF01782.18 KEZ36176.1 - 1.5e-21 76.4 0.6 2e-21 76.0 0.6 1.2 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 KEZ36176.1 - 1.7e-09 37.6 0.1 5.1e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 PRC-barrel domain tRNA_m1G_MT PF01746.21 KEZ36177.1 - 6.1e-66 221.8 0.0 7.6e-66 221.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L19 PF01245.20 KEZ36178.1 - 2e-49 166.1 0.5 2.2e-49 166.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_S24 PF00717.23 KEZ36179.1 - 4.2e-12 45.8 0.0 1e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 KEZ36179.1 - 6.2e-09 35.8 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 RNase_HII PF01351.18 KEZ36180.1 - 4e-29 101.9 0.3 5.2e-29 101.5 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF2469 PF10611.9 KEZ36181.1 - 5.3e-49 164.9 6.6 5.8e-49 164.8 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) UPF0102 PF02021.17 KEZ36182.1 - 2.9e-27 94.7 0.1 3.4e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DUF4143 PF13635.6 KEZ36182.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) NERD PF08378.11 KEZ36182.1 - 0.027 15.0 0.0 0.039 14.4 0.0 1.4 1 1 0 1 1 1 0 Nuclease-related domain Mg_chelatase PF01078.21 KEZ36183.1 - 6.3e-44 149.8 0.1 8.9e-44 149.4 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 KEZ36183.1 - 2.8e-37 127.2 0.0 4.5e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 KEZ36183.1 - 4.7e-08 32.8 0.4 1e-07 31.7 0.4 1.5 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Sigma54_activat PF00158.26 KEZ36183.1 - 0.00087 19.0 0.0 0.013 15.3 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KEZ36183.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 KEZ36183.1 - 0.012 14.4 0.1 0.042 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEZ36183.1 - 0.016 15.4 0.1 0.055 13.6 0.0 1.9 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 KEZ36183.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KEZ36183.1 - 0.048 14.1 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ36183.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEZ36183.1 - 0.077 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEZ36183.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KEZ36183.1 - 0.26 11.1 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Resolvase PF00239.21 KEZ36184.1 - 1.3e-18 67.5 0.5 2.4e-18 66.6 0.1 1.6 2 0 0 2 2 2 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 KEZ36184.1 - 2.9e-07 30.9 4.0 7e-07 29.7 3.2 2.0 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 KEZ36184.1 - 0.0082 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Recombinase PLDc_3 PF13918.6 KEZ36184.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain Helitron_like_N PF14214.6 KEZ36186.1 - 0.083 13.1 0.4 2 8.6 0.1 2.1 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus DUF3039 PF11238.8 KEZ36186.1 - 1.1 9.1 5.2 32 4.4 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3039) HTH_17 PF12728.7 KEZ36187.1 - 5.1e-15 55.4 0.0 6.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_integrase PF00589.22 KEZ36188.1 - 3.5e-24 85.5 0.0 5.7e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ36188.1 - 2.8e-05 24.3 0.0 6.1e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain AAA_31 PF13614.6 KEZ36189.1 - 7e-28 97.7 0.0 4.1e-27 95.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ36189.1 - 3.4e-15 56.2 0.0 5.8e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KEZ36189.1 - 2.3e-09 36.9 0.0 2.3e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 KEZ36189.1 - 7e-08 32.2 0.0 4.3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KEZ36189.1 - 5.4e-07 29.1 0.0 7.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 KEZ36189.1 - 1.6e-05 24.5 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KEZ36189.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 KEZ36189.1 - 0.0044 16.8 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KEZ36189.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CTP_synth_N PF06418.14 KEZ36189.1 - 0.035 13.4 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 CTP synthase N-terminus ATP_bind_1 PF03029.17 KEZ36189.1 - 0.035 13.9 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KEZ36189.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MDMPI_N PF11716.8 KEZ36190.1 - 1.4e-18 67.9 15.2 1.4e-18 67.9 15.2 1.8 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 KEZ36190.1 - 0.00097 19.7 2.9 0.0019 18.7 2.9 1.4 1 0 0 1 1 1 1 DinB superfamily DUF3335 PF11814.8 KEZ36192.1 - 0.057 12.9 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family Gram_pos_anchor PF00746.21 KEZ36192.1 - 0.17 11.9 3.4 0.29 11.1 3.4 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NERD PF08378.11 KEZ36193.1 - 9.4e-13 48.6 0.0 1.9e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Nuclease-related domain GCS2 PF04107.13 KEZ36194.1 - 1e-55 189.1 0.2 1.5e-55 188.6 0.2 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) FGE-sulfatase PF03781.16 KEZ36195.1 - 2.6e-55 187.8 5.4 3.4e-55 187.4 5.4 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KEZ36195.1 - 3.7e-27 95.4 6.8 4.3e-27 95.1 1.6 2.4 2 0 0 2 2 2 1 DinB superfamily GATase_6 PF13522.6 KEZ36196.1 - 4.8e-18 65.6 0.1 6.9e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KEZ36196.1 - 1.8e-07 30.3 0.0 8.8e-07 28.1 0.0 1.8 1 1 1 2 2 2 1 Glutamine amidotransferases class-II Methyltransf_33 PF10017.9 KEZ36197.1 - 2.4e-111 371.8 0.0 2.7e-111 371.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent ILVD_EDD PF00920.21 KEZ36198.1 - 2.6e-209 696.1 0.4 3e-209 695.9 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.11 KEZ36199.1 - 0.019 15.3 1.6 0.028 14.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) ABM PF03992.16 KEZ36200.1 - 1.8e-10 40.8 0.0 2.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DnaB_C PF03796.15 KEZ36201.1 - 9.8e-105 349.5 0.2 1.2e-104 349.1 0.2 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 KEZ36201.1 - 2.4e-33 114.3 0.0 4.6e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 KEZ36201.1 - 4.8e-15 55.6 0.1 1.2e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KEZ36201.1 - 6.4e-05 22.4 0.2 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 KaiC Ribosomal_L9_C PF03948.14 KEZ36202.1 - 3e-27 94.9 0.1 4e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 KEZ36202.1 - 5.5e-19 67.5 0.1 1.6e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_S18 PF01084.20 KEZ36203.1 - 2.1e-22 79.0 0.1 2.6e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 Helicase_C PF00271.31 KEZ36203.1 - 0.061 13.7 0.0 0.068 13.5 0.0 1.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SSB PF00436.25 KEZ36204.1 - 6.1e-30 103.3 0.0 7.8e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 KEZ36204.1 - 1.7e-05 24.7 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KEZ36204.1 - 0.0024 18.1 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_S3_C PF00189.20 KEZ36204.1 - 0.079 13.5 0.1 0.12 12.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain GRP PF07172.11 KEZ36204.1 - 0.38 11.5 14.7 0.63 10.8 14.7 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_S6 PF01250.17 KEZ36205.1 - 7.2e-26 90.3 0.0 8.2e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 DUF1345 PF07077.11 KEZ36206.1 - 0.088 12.5 1.8 0.11 12.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) PMT_2 PF13231.6 KEZ36207.1 - 0.00071 19.8 8.6 0.00071 19.8 8.6 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GT87 PF09594.10 KEZ36208.1 - 1.5e-07 31.4 43.8 1.5e-07 31.4 43.8 3.5 1 1 2 3 3 3 2 Glycosyltransferase family 87 Mannosyl_trans PF05007.13 KEZ36208.1 - 5.3e-05 23.2 9.5 0.01 15.7 3.3 2.6 2 1 0 2 2 2 2 Mannosyltransferase (PIG-M) Transgly PF00912.22 KEZ36209.1 - 1.1e-60 204.2 0.0 1.7e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KEZ36209.1 - 1.1e-23 83.9 1.4 2.5e-23 82.8 1.4 1.5 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain DUF5318 PF17249.2 KEZ36210.1 - 1.1e-50 170.8 0.0 1.5e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5318) DUF2225 PF09986.9 KEZ36210.1 - 0.031 14.0 0.4 0.066 12.9 0.4 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PadR PF03551.14 KEZ36211.1 - 2.1e-18 66.1 0.0 3.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KEZ36211.1 - 0.0068 16.6 0.0 0.086 13.0 0.0 2.4 2 1 0 2 2 2 1 Winged helix DNA-binding domain Vir_act_alpha_C PF10400.9 KEZ36211.1 - 0.03 15.0 1.3 0.055 14.2 1.3 1.3 1 0 0 1 1 1 0 Virulence activator alpha C-term Inos-1-P_synth PF01658.17 KEZ36212.1 - 1.6e-32 112.0 0.0 2.6e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 KEZ36212.1 - 8.3e-05 22.1 0.0 0.00019 20.9 0.0 1.5 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase DELLA PF12041.8 KEZ36212.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal MFS_1 PF07690.16 KEZ36213.1 - 1.2e-08 34.3 10.3 1.2e-08 34.3 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KEZ36213.1 - 0.058 11.8 35.6 0.087 11.2 35.6 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector PolyA_pol PF01743.20 KEZ36214.1 - 2.2e-31 108.9 0.0 6.1e-31 107.5 0.0 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KEZ36214.1 - 1.7e-16 59.7 0.1 7.9e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 KEZ36214.1 - 1.4e-12 47.9 1.7 1.4e-12 47.9 1.7 2.0 2 0 0 2 2 2 1 HD domain tRNA_NucTran2_2 PF13735.6 KEZ36214.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Wbp11 PF09429.10 KEZ36214.1 - 0.19 12.1 0.4 14 6.2 0.1 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 MurJ PF03023.14 KEZ36218.1 - 1e-90 304.5 22.2 1.4e-90 304.1 22.2 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 KEZ36218.1 - 9e-05 22.6 14.6 9e-05 22.6 14.6 4.7 3 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Yip1 PF04893.17 KEZ36218.1 - 0.00026 20.8 7.6 0.00026 20.8 7.6 4.6 1 1 3 4 4 4 1 Yip1 domain MatE PF01554.18 KEZ36218.1 - 0.0013 18.4 12.1 0.0013 18.4 12.1 3.3 4 0 0 4 4 4 2 MatE Pkinase PF00069.25 KEZ36219.1 - 2.4e-06 27.1 0.0 5.3e-06 26.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KEZ36219.1 - 0.00069 19.6 2.6 0.2 11.6 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ36219.1 - 0.0017 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC2 PF13490.6 KEZ36221.1 - 0.12 12.6 4.4 0.22 11.8 1.1 2.8 2 1 0 2 2 2 0 Putative zinc-finger Pyr_redox_2 PF07992.14 KEZ36223.1 - 8.4e-48 163.1 0.8 9.9e-48 162.8 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ36223.1 - 1.8e-19 70.2 0.0 6.6e-16 58.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ36223.1 - 1.9e-19 70.0 1.3 5.2e-18 65.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ36223.1 - 2.7e-08 33.4 0.1 1.5e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KEZ36223.1 - 3.1e-06 27.3 1.8 0.00043 20.4 0.1 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEZ36223.1 - 1.9e-05 24.2 0.5 7.9e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KEZ36223.1 - 2.4e-05 24.1 10.5 0.045 13.3 0.0 4.1 2 2 2 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ36223.1 - 2.8e-05 23.4 9.2 0.00021 20.5 0.6 4.1 2 1 2 5 5 5 1 FAD binding domain HI0933_like PF03486.14 KEZ36223.1 - 3e-05 22.9 1.0 0.0083 14.9 0.2 3.4 3 1 1 4 4 4 1 HI0933-like protein GIDA PF01134.22 KEZ36223.1 - 0.00012 21.3 3.3 0.02 14.0 0.2 3.2 4 0 0 4 4 4 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 KEZ36223.1 - 0.00097 18.1 0.1 0.13 11.1 0.0 3.2 4 0 0 4 4 4 1 Tryptophan halogenase NAD_binding_7 PF13241.6 KEZ36223.1 - 0.0015 19.0 0.4 0.048 14.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KEZ36223.1 - 0.0021 17.3 0.1 0.061 12.5 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KEZ36223.1 - 0.0062 15.8 0.3 0.3 10.3 0.1 2.5 2 1 1 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KEZ36223.1 - 0.078 12.0 0.7 1.4 7.9 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Thioredoxin PF00085.20 KEZ36224.1 - 1.2e-30 105.5 0.0 1.3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KEZ36224.1 - 2.5e-09 37.3 0.0 1.2e-07 32.0 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KEZ36224.1 - 1.4e-07 31.9 0.1 1.7e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KEZ36224.1 - 1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KEZ36224.1 - 2e-05 24.4 0.1 9.8e-05 22.1 0.0 1.8 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 KEZ36224.1 - 4.2e-05 23.3 0.1 4.9e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KEZ36224.1 - 5.6e-05 23.0 0.0 0.00039 20.3 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.6 KEZ36224.1 - 8.5e-05 22.5 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 KEZ36224.1 - 0.00049 20.4 0.0 0.00062 20.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 KEZ36224.1 - 0.0014 18.5 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 KEZ36224.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin KaiB PF07689.12 KEZ36224.1 - 0.031 14.0 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 KaiB domain OST3_OST6 PF04756.13 KEZ36224.1 - 0.055 12.8 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family EKR PF10371.9 KEZ36224.1 - 0.14 12.0 0.1 0.99 9.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function Amidase_3 PF01520.18 KEZ36225.1 - 3.9e-37 128.0 0.0 5.4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 KEZ36225.1 - 6.3e-29 100.0 0.1 1.7e-15 56.9 0.0 3.8 4 0 0 4 4 4 2 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 KEZ36225.1 - 8.2e-10 38.8 0.0 0.012 15.9 0.0 3.5 2 1 1 3 3 3 3 Predicted Peptidoglycan domain PG_binding_2 PF08823.11 KEZ36225.1 - 0.016 15.5 0.0 3.1 8.2 0.0 3.4 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Acetyltransf_1 PF00583.25 KEZ36226.1 - 0.0019 18.4 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEZ36226.1 - 0.0042 17.0 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEZ36226.1 - 0.028 14.5 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ParBc PF02195.18 KEZ36227.1 - 3.6e-26 91.3 0.4 9.1e-26 90.0 0.4 1.7 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 KEZ36227.1 - 4e-15 55.3 0.2 9.9e-15 54.1 0.2 1.7 1 0 0 1 1 1 1 HTH domain found in ParB protein TrmB PF01978.19 KEZ36227.1 - 0.00036 20.4 0.1 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KEZ36227.1 - 0.0018 18.2 0.1 0.0056 16.6 0.1 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KEZ36227.1 - 0.0059 16.4 0.1 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain KorB PF08535.10 KEZ36227.1 - 0.012 15.6 0.1 0.4 10.8 0.0 2.4 1 1 1 2 2 2 0 KorB domain MarR PF01047.22 KEZ36227.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 MarR family Sigma70_r4 PF04545.16 KEZ36227.1 - 0.088 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 AAA_31 PF13614.6 KEZ36228.1 - 8.1e-60 201.7 0.0 1.2e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ36228.1 - 1.2e-26 93.2 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KEZ36228.1 - 1.1e-12 47.8 0.7 2.7e-08 33.4 0.4 2.2 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 KEZ36228.1 - 1.6e-11 44.2 1.9 3e-10 40.0 1.9 2.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KEZ36228.1 - 4.2e-10 39.5 0.0 1.4e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KEZ36228.1 - 1e-08 35.0 0.0 6.8e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KEZ36228.1 - 2.5e-07 30.2 0.2 5e-07 29.2 0.2 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 KEZ36228.1 - 0.00047 19.5 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 KEZ36228.1 - 0.0038 17.0 0.2 0.0081 16.0 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop LpxK PF02606.14 KEZ36228.1 - 0.0053 15.9 0.1 0.0087 15.2 0.1 1.3 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Methyltransf_24 PF13578.6 KEZ36228.1 - 0.0054 17.7 0.0 0.028 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MeaB PF03308.16 KEZ36228.1 - 0.0055 15.7 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KEZ36228.1 - 0.014 15.0 0.1 0.099 12.3 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KEZ36228.1 - 0.024 14.4 0.1 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KEZ36228.1 - 0.13 11.9 1.0 0.39 10.3 1.0 2.0 1 1 0 1 1 1 0 AAA domain FTHFS PF01268.19 KEZ36228.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase GidB PF02527.15 KEZ36229.1 - 5.8e-42 143.1 0.0 7.5e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 KEZ36229.1 - 0.0043 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ36229.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PMT_2 PF13231.6 KEZ36230.1 - 0.12 12.5 7.4 0.69 10.1 7.4 2.3 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase R3H PF01424.22 KEZ36231.1 - 2.4e-12 46.6 0.0 4.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 R3H domain KH_4 PF13083.6 KEZ36231.1 - 4.7e-06 26.4 0.2 8.2e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 KH domain 60KD_IMP PF02096.20 KEZ36232.1 - 7.7e-53 178.8 3.8 9.5e-53 178.5 3.8 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein OSTbeta PF15048.6 KEZ36232.1 - 0.075 13.2 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein YidD PF01809.18 KEZ36233.1 - 2.3e-22 78.7 0.1 3.5e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Ribonuclease_P PF00825.18 KEZ36234.1 - 5.2e-20 71.6 0.2 5.8e-20 71.4 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease P Rossmann-like PF10727.9 KEZ36234.1 - 0.07 13.0 0.6 0.19 11.6 0.4 1.9 1 1 1 2 2 2 0 Rossmann-like domain Ribosomal_L34 PF00468.17 KEZ36235.1 - 2.3e-20 72.3 12.2 2.5e-20 72.2 12.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Bac_DnaA PF00308.18 KEZ36237.1 - 1.5e-100 335.6 0.0 2.2e-100 335.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 KEZ36237.1 - 6.8e-31 106.1 0.0 1.3e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 KEZ36237.1 - 3.8e-12 46.3 0.0 7.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 KEZ36237.1 - 2.1e-06 28.2 0.0 5.7e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ36237.1 - 0.0014 18.9 1.3 2 8.7 0.5 2.4 1 1 0 2 2 2 2 AAA domain DnaA_N PF11638.8 KEZ36237.1 - 0.0045 16.7 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 DnaA N-terminal domain ATPase_2 PF01637.18 KEZ36237.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KEZ36237.1 - 0.01 16.2 0.0 0.032 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KEZ36237.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ36237.1 - 0.021 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEZ36237.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DNA_pol3_beta PF00712.19 KEZ36238.1 - 9.7e-37 125.8 0.0 8.8e-28 96.9 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 KEZ36238.1 - 3.8e-29 101.3 0.0 3.6e-16 59.4 0.0 3.4 3 0 0 3 3 3 3 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 KEZ36238.1 - 7.2e-25 87.2 0.0 3.4e-23 81.8 0.0 2.6 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain HTH_Crp_2 PF13545.6 KEZ36238.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain SMC_N PF02463.19 KEZ36239.1 - 6.5e-17 61.7 0.0 1.2e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ36239.1 - 4.1e-06 27.5 0.0 5.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KEZ36239.1 - 1.3e-05 25.1 0.2 0.0084 15.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEZ36239.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEZ36239.1 - 0.029 14.1 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KEZ36239.1 - 0.039 14.2 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DciA PF05258.12 KEZ36240.1 - 7.8e-25 87.1 0.1 1.2e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA DNA_gyraseB PF00204.25 KEZ36241.1 - 6.8e-57 191.7 0.3 1e-56 191.2 0.3 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 KEZ36241.1 - 2.8e-27 94.7 0.0 5.6e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 KEZ36241.1 - 1e-22 80.7 0.0 4.9e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KEZ36241.1 - 5.5e-17 61.9 0.0 9.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KEZ36241.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_topoisoIV PF00521.20 KEZ36242.1 - 9.1e-150 499.2 0.0 1.1e-149 498.9 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 KEZ36242.1 - 2.3e-67 222.2 7.0 2.9e-12 45.9 0.3 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller COMMD1_N PF17221.3 KEZ36242.1 - 0.11 12.8 0.0 0.44 10.9 0.0 1.9 1 1 0 1 1 1 0 COMMD1 N-terminal domain DUF3566 PF12089.8 KEZ36244.1 - 7.9e-40 135.9 4.7 1.2e-39 135.4 4.7 1.2 1 0 0 1 1 1 1 Transmembrane domain of unknown function (DUF3566) Dehydrin PF00257.19 KEZ36244.1 - 0.031 14.8 0.5 0.043 14.4 0.5 1.2 1 0 0 1 1 1 0 Dehydrin DUF5408 PF17402.2 KEZ36244.1 - 0.62 10.0 3.3 0.53 10.2 0.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Glycos_transf_1 PF00534.20 KEZ36245.1 - 2.2e-30 105.5 0.0 3.1e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ36245.1 - 5.7e-27 94.8 0.5 1.3e-26 93.6 0.4 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ36245.1 - 2e-26 93.3 19.7 8.5e-26 91.3 9.7 2.8 1 1 1 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ36245.1 - 3.7e-24 85.6 0.5 1.5e-23 83.7 0.3 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ36245.1 - 3.1e-13 49.9 0.0 5.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KEZ36245.1 - 0.19 11.4 0.0 0.58 9.8 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Methyltransf_11 PF08241.12 KEZ36246.1 - 1.1e-19 70.8 0.0 1.8e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ36246.1 - 1.6e-17 64.0 0.1 2.4e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ36246.1 - 5.8e-16 58.8 0.0 9.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ36246.1 - 1e-14 54.6 0.0 2.3e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ36246.1 - 1.2e-09 38.8 0.0 1.9e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ36246.1 - 2.5e-07 30.3 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEZ36246.1 - 1.3e-05 24.6 0.0 2.3e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KEZ36246.1 - 0.00053 19.5 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 KEZ36246.1 - 0.0033 16.0 0.0 0.0048 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KEZ36246.1 - 0.013 15.3 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase Cons_hypoth95 PF03602.15 KEZ36246.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KEZ36246.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Prenyltrans PF00432.21 KEZ36247.1 - 0.00054 19.6 0.0 0.0066 16.2 0.4 2.6 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEZ36247.1 - 0.028 13.5 0.6 2.3 7.2 0.1 2.4 2 1 1 3 3 3 0 Squalene-hopene cyclase N-terminal domain Methyltransf_24 PF13578.6 KEZ36248.1 - 2.8e-22 79.8 0.4 4.3e-22 79.2 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KEZ36248.1 - 0.025 14.3 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Cephalosporin hydroxylase Pep_deformylase PF01327.21 KEZ36249.1 - 1.1e-45 155.1 0.0 1.5e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Glyco_tranf_2_3 PF13641.6 KEZ36250.1 - 9.7e-25 87.8 0.2 8e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ36250.1 - 4.2e-20 72.5 3.4 2.3e-19 70.1 4.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEZ36250.1 - 6.4e-13 48.9 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ36250.1 - 4.4e-07 29.5 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Acyl_transf_3 PF01757.22 KEZ36251.1 - 6.7e-21 74.7 33.9 8.8e-21 74.3 33.9 1.1 1 0 0 1 1 1 1 Acyltransferase family Strabismus PF06638.11 KEZ36251.1 - 0.39 9.3 3.7 0.56 8.8 3.7 1.1 1 0 0 1 1 1 0 Strabismus protein GspL_C PF12693.7 KEZ36251.1 - 0.43 10.4 3.0 1 9.2 3.0 1.6 1 0 0 1 1 1 0 GspL periplasmic domain DUF872 PF05915.12 KEZ36251.1 - 0.55 10.4 3.5 3.6 7.8 0.1 2.9 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Wzy_C_2 PF11846.8 KEZ36251.1 - 4.3 7.2 16.3 0.59 10.0 1.3 3.7 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal HD_6 PF18019.1 KEZ36252.1 - 1.2e-39 136.5 1.0 2.2e-39 135.6 1.0 1.4 1 0 0 1 1 1 1 HD domain Cas3_C PF18395.1 KEZ36252.1 - 7.6e-22 77.8 0.1 2e-21 76.5 0.1 1.8 1 0 0 1 1 1 1 Cas3 C-terminal domain DEAD PF00270.29 KEZ36252.1 - 7.3e-06 25.9 0.0 0.023 14.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ36252.1 - 3.2e-05 24.2 0.0 5.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HD PF01966.22 KEZ36252.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 HD domain CRISPR_Cse1 PF09481.10 KEZ36253.1 - 1.4e-108 364.0 7.9 1.6e-108 363.8 7.9 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) CRISPR_Cse2 PF09485.10 KEZ36254.1 - 3.2e-32 112.0 1.3 4e-32 111.7 1.3 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) Cas_CT1975 PF09344.10 KEZ36255.1 - 4.4e-118 394.9 0.1 5.3e-118 394.6 0.1 1.0 1 0 0 1 1 1 1 CT1975-like protein Cas_Cas7 PF05107.12 KEZ36255.1 - 0.005 16.4 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Cas7 UPF0262 PF06793.12 KEZ36255.1 - 0.2 11.8 0.7 0.36 10.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) PhageMin_Tail PF10145.9 KEZ36255.1 - 4.7 7.0 7.5 0.58 10.0 0.4 2.9 3 1 1 4 4 4 0 Phage-related minor tail protein Cas_Cas5d PF09704.10 KEZ36256.1 - 5.4e-52 176.8 0.2 6.6e-52 176.5 0.2 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) CRISPR_assoc PF08798.11 KEZ36257.1 - 7.9e-66 222.4 0.5 9.1e-66 222.2 0.5 1.0 1 0 0 1 1 1 1 CRISPR associated protein Cas_Cas1 PF01867.16 KEZ36258.1 - 6.4e-16 58.3 0.0 1.4e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 CRISPR associated protein Cas1 Cas_Cas2CT1978 PF09707.10 KEZ36259.1 - 2.7e-33 113.9 0.1 3e-33 113.7 0.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas2CT1978) Glyco_hydro_16 PF00722.21 KEZ36260.1 - 1.9e-23 82.8 0.0 2.2e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KEZ36260.1 - 2.1e-05 23.1 0.1 0.081 11.3 0.0 2.4 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Laminin_G_3 PF13385.6 KEZ36260.1 - 0.034 14.3 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Hexapep PF00132.24 KEZ36261.1 - 2.2e-11 43.0 7.5 1.7e-06 27.5 0.2 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ36261.1 - 5.6e-05 22.8 13.5 7.9e-05 22.3 0.7 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Lysine_decarbox PF03641.14 KEZ36262.1 - 3.6e-32 111.2 0.0 5.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KEZ36262.1 - 1.6e-15 57.0 0.0 2.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 KEZ36263.1 - 5.8e-30 104.1 0.0 7e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KEZ36263.1 - 4.3e-17 62.1 0.1 5.2e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family Pterin_bind PF00809.22 KEZ36264.1 - 5.4e-60 203.1 0.0 7.1e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme DivIVA PF05103.13 KEZ36266.1 - 0.0065 16.6 0.0 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 DivIVA protein Molybdopterin_N PF18364.1 KEZ36266.1 - 0.07 13.2 0.2 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain DUF3117 PF11314.8 KEZ36267.1 - 1.5e-28 98.3 2.1 1.7e-28 98.2 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3117) Peptidase_M17 PF00883.21 KEZ36268.1 - 7.9e-109 363.7 0.2 1.9e-94 316.4 2.1 2.3 2 0 0 2 2 2 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KEZ36268.1 - 2.8e-06 27.2 0.6 2.8e-06 27.2 0.6 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Methyltransf_3 PF01596.17 KEZ36270.1 - 8.9e-22 77.3 0.0 1.2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KEZ36270.1 - 1.1e-14 55.4 0.1 2.6e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ36270.1 - 2.7e-11 44.0 0.0 2.1e-10 41.2 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ36270.1 - 2.2e-09 37.3 0.0 3.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ36270.1 - 2.6e-07 31.2 0.1 9.6e-07 29.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEZ36270.1 - 1.2e-06 28.2 0.0 3.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain GCD14 PF08704.10 KEZ36270.1 - 0.00057 19.6 0.0 0.00074 19.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.12 KEZ36270.1 - 0.0015 19.3 0.1 0.009 16.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ36270.1 - 0.0025 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEZ36270.1 - 0.072 12.9 0.0 0.92 9.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Sigma70_r2 PF04542.14 KEZ36271.1 - 3.7e-21 74.7 0.3 6.6e-21 73.9 0.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ36271.1 - 9.4e-17 60.4 0.0 1.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ36271.1 - 1.3e-11 43.9 0.0 2.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KEZ36271.1 - 0.0084 15.9 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 KEZ36271.1 - 0.027 14.3 0.0 0.092 12.6 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KEZ36271.1 - 0.03 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 KEZ36271.1 - 0.034 14.0 0.1 0.057 13.3 0.1 1.4 1 1 0 1 1 1 0 ECF sigma factor UBM PF14377.6 KEZ36271.1 - 0.46 10.0 2.9 0.33 10.5 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin binding region Trypsin_2 PF13365.6 KEZ36273.1 - 1.8e-29 103.6 2.0 1.8e-29 103.6 2.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KEZ36273.1 - 1.3e-16 60.6 0.2 2.5e-16 59.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 KEZ36273.1 - 2e-12 47.4 0.0 3.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KEZ36273.1 - 1.5e-09 37.5 0.4 3e-09 36.6 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEZ36273.1 - 4.4e-08 33.4 0.0 9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 KEZ36273.1 - 6.9e-05 21.7 1.4 0.024 13.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 MttA_Hcf106 PF02416.16 KEZ36274.1 - 3.1e-10 39.2 0.0 4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family ParA PF10609.9 KEZ36275.1 - 3.8e-87 291.8 0.0 4.6e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 KEZ36275.1 - 1.2e-16 60.7 1.7 2.4e-16 59.7 1.7 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 KEZ36275.1 - 3.9e-11 43.1 0.1 7.4e-10 39.0 0.1 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEZ36275.1 - 1.1e-07 32.0 0.1 5.4e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KEZ36275.1 - 2.3e-06 27.1 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KEZ36275.1 - 0.0027 16.9 0.6 0.0049 16.1 0.2 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KEZ36275.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KEZ36275.1 - 0.011 15.3 1.4 0.025 14.2 0.3 2.0 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 KEZ36275.1 - 0.027 13.9 0.6 0.46 9.9 0.4 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 KEZ36275.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 KEZ36275.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 KEZ36275.1 - 0.11 12.3 1.0 3.1 7.6 0.3 2.2 2 0 0 2 2 2 0 AAA domain BON PF04972.17 KEZ36275.1 - 0.11 12.8 0.5 0.11 12.8 0.5 2.1 2 0 0 2 2 2 0 BON domain Desulfoferrod_N PF06397.12 KEZ36275.1 - 0.12 12.0 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Lar_restr_allev PF14354.6 KEZ36275.1 - 0.19 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar MarR_2 PF12802.7 KEZ36276.1 - 8.6e-14 51.2 5.4 1.4e-13 50.5 1.8 2.6 3 0 0 3 3 3 1 MarR family MarR PF01047.22 KEZ36276.1 - 1.6e-12 47.2 0.0 3.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KEZ36276.1 - 1.1e-07 31.5 1.9 3.2e-06 26.9 0.9 2.9 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KEZ36276.1 - 3.7e-06 26.4 0.3 7.2e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 KEZ36276.1 - 6.9e-06 26.5 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 KEZ36276.1 - 0.00031 21.0 0.0 0.0007 19.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 KEZ36276.1 - 0.00061 19.7 0.2 0.0023 17.9 0.1 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KEZ36276.1 - 0.0014 18.7 0.0 0.049 13.8 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HxlR PF01638.17 KEZ36276.1 - 0.0064 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix GntR PF00392.21 KEZ36276.1 - 0.0091 15.6 1.2 0.023 14.4 1.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 KEZ36276.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KEZ36276.1 - 0.07 13.2 0.6 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_34 PF13601.6 KEZ36276.1 - 0.093 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain PHP PF02811.19 KEZ36277.1 - 2.1e-06 28.1 0.0 2.1e-06 28.1 0.0 1.2 1 1 0 1 1 1 1 PHP domain AP_endonuc_2 PF01261.24 KEZ36277.1 - 0.057 12.9 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Aldedh PF00171.22 KEZ36278.1 - 1.5e-125 419.4 0.1 1.7e-125 419.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding_C PF13193.6 KEZ36278.1 - 0.46 11.5 4.2 0.23 12.5 1.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Aminotran_3 PF00202.21 KEZ36279.1 - 4.5e-119 397.7 0.0 5.1e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Carla_C4 PF01623.17 KEZ36280.1 - 0.028 14.4 0.4 0.044 13.7 0.4 1.2 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein DAGK_cat PF00781.24 KEZ36281.1 - 2.7e-20 72.2 0.1 3.7e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain COX1 PF00115.20 KEZ36282.1 - 9.1e-39 133.5 11.9 1.1e-38 133.3 11.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 KEZ36283.1 - 1.8e-58 198.5 23.7 2e-58 198.3 23.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I PhoD PF09423.10 KEZ36284.1 - 2.7e-102 342.4 0.5 3.2e-102 342.1 0.5 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KEZ36284.1 - 4.2e-20 72.1 0.1 4.2e-20 72.1 0.1 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KEZ36284.1 - 5.9e-05 23.6 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain SUFU PF05076.13 KEZ36285.1 - 4.5e-34 117.9 0.0 5.3e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) TerD PF02342.18 KEZ36286.1 - 9.8e-70 233.8 0.0 1.7e-40 138.6 0.0 2.9 2 1 0 2 2 2 2 TerD domain MgtE_N PF03448.17 KEZ36287.1 - 2.1e-25 89.3 8.9 4.1e-25 88.3 8.9 1.5 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 KEZ36287.1 - 6.9e-15 55.2 1.0 3.8e-08 33.7 0.7 3.5 2 1 1 3 3 3 2 CBS domain PRC PF05239.16 KEZ36287.1 - 8.4e-05 22.6 0.0 0.016 15.2 0.0 2.6 2 0 0 2 2 2 2 PRC-barrel domain FliG_M PF14841.6 KEZ36287.1 - 0.00023 21.3 1.8 0.65 10.3 0.6 3.5 1 1 2 3 3 3 2 FliG middle domain FliG_N PF14842.6 KEZ36287.1 - 0.00092 19.7 0.9 0.18 12.3 0.0 2.5 1 1 1 2 2 2 2 FliG N-terminal domain DUF1003 PF06210.11 KEZ36288.1 - 2.7e-36 123.8 0.5 2.7e-36 123.8 0.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) GWT1 PF06423.12 KEZ36288.1 - 0.17 12.0 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 GWT1 CM_2 PF01817.21 KEZ36289.1 - 1.9e-08 34.6 0.6 2.2e-08 34.3 0.6 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Osmo_CC PF08946.10 KEZ36289.1 - 0.13 12.6 0.8 0.22 11.8 0.8 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil PDDEXK_1 PF12705.7 KEZ36290.1 - 1.1e-33 117.3 0.0 1.2e-33 117.1 0.0 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 KEZ36290.1 - 1.6e-05 24.4 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) Cas_Cas4 PF01930.17 KEZ36290.1 - 0.13 12.3 0.0 0.51 10.4 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF83 Aminotran_1_2 PF00155.21 KEZ36291.1 - 1.9e-58 198.4 0.0 2.1e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEZ36291.1 - 6.8e-08 32.2 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEZ36291.1 - 1.7e-06 26.9 0.0 2.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEZ36291.1 - 0.00032 19.8 0.0 0.00077 18.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ36291.1 - 0.0018 17.6 0.0 0.0041 16.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase NfrA_C PF13283.6 KEZ36291.1 - 0.052 13.0 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term DUF4824 PF16106.5 KEZ36291.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) ABM PF03992.16 KEZ36293.1 - 7.7e-16 58.0 0.1 1.1e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AAA_31 PF13614.6 KEZ36294.1 - 3.8e-42 144.2 0.0 9.3e-42 142.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KEZ36294.1 - 1.8e-11 44.2 0.0 2.8e-11 43.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KEZ36294.1 - 8.2e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 KEZ36294.1 - 0.00022 20.6 0.0 0.00047 19.5 0.0 1.5 2 0 0 2 2 2 1 ATPase MipZ zinc_ribbon_4 PF13717.6 KEZ36295.1 - 0.04 13.8 2.4 5.8 6.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KEZ36295.1 - 0.087 12.3 2.5 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEZ36295.1 - 0.24 11.6 1.6 4.8 7.4 1.6 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DEAD PF00270.29 KEZ36296.1 - 1.3e-49 168.3 0.0 2.2e-48 164.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ36296.1 - 1.3e-29 102.8 0.0 4.1e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Methyltransf_17 PF12692.7 KEZ36296.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase UTP25 PF06862.12 KEZ36296.1 - 0.16 10.7 0.0 5.2 5.7 0.0 2.3 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 KEZ36296.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MiaE_2 PF13794.6 KEZ36297.1 - 6.4e-81 270.5 4.8 8.1e-81 270.2 4.8 1.1 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like TetR_C_36 PF18598.1 KEZ36297.1 - 0.019 14.9 0.3 0.041 13.8 0.3 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3107 PF11305.8 KEZ36298.1 - 7.4e-29 99.8 0.4 8.2e-29 99.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) TetR_N PF00440.23 KEZ36299.1 - 4e-18 64.9 0.2 7.6e-18 64.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KEZ36299.1 - 0.002 18.4 0.3 0.0032 17.7 0.3 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 KEZ36299.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LacI PF00356.21 KEZ36299.1 - 0.14 12.0 0.1 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Ku PF02735.16 KEZ36301.1 - 3.8e-39 134.5 0.0 5.4e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain CsbD PF05532.12 KEZ36302.1 - 7.5e-15 54.6 7.0 8.1e-15 54.5 7.0 1.0 1 0 0 1 1 1 1 CsbD-like ThiF PF00899.21 KEZ36303.1 - 2.2e-64 217.1 0.0 2.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KEZ36303.1 - 6.5e-15 55.6 0.0 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DNA_binding_1 PF01035.20 KEZ36304.1 - 6.7e-17 61.4 0.1 8.5e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain adh_short_C2 PF13561.6 KEZ36305.1 - 3.3e-67 226.4 3.4 3.9e-67 226.2 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ36305.1 - 9.5e-58 194.9 0.4 1.2e-57 194.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ36305.1 - 3.5e-12 46.6 1.0 5.2e-12 46.0 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ36305.1 - 0.0019 17.7 0.6 0.013 15.0 0.1 2.3 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.13 KEZ36305.1 - 0.031 14.1 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) TrkA_N PF02254.18 KEZ36305.1 - 0.036 14.3 0.2 0.067 13.5 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KEZ36305.1 - 0.043 13.7 0.3 0.067 13.1 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KEZ36305.1 - 0.073 13.1 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LytR_C PF13399.6 KEZ36305.1 - 0.081 13.9 1.8 0.22 12.5 1.8 1.7 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator 2-Hacid_dh_C PF02826.19 KEZ36305.1 - 0.084 12.2 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KEZ36305.1 - 0.098 13.4 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KEZ36305.1 - 0.12 12.1 0.2 0.54 10.0 0.1 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UDPG_MGDP_dh_N PF03721.14 KEZ36305.1 - 0.14 11.7 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UvrD-helicase PF00580.21 KEZ36306.1 - 3.1e-49 168.2 0.0 1e-27 97.5 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PDDEXK_1 PF12705.7 KEZ36306.1 - 1.9e-36 126.3 0.0 3.3e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.6 KEZ36306.1 - 3.8e-32 111.6 0.0 6.5e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 KEZ36306.1 - 9.9e-22 77.8 0.0 5e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KEZ36306.1 - 5.7e-10 38.9 1.6 0.00039 20.2 1.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ36306.1 - 2.1e-05 24.4 8.6 0.0004 20.1 0.9 3.6 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KEZ36306.1 - 0.00013 21.8 0.3 0.54 9.9 0.1 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KEZ36306.1 - 0.0042 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2800 PF10926.8 KEZ36306.1 - 0.0078 15.5 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2800) AAA_11 PF13086.6 KEZ36306.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KEZ36306.1 - 0.2 11.5 0.5 0.39 10.6 0.5 1.4 1 0 0 1 1 1 0 Helicase PhoH PF02562.16 KEZ36306.1 - 0.23 10.9 0.0 1 8.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 KEZ36307.1 - 8.9e-43 147.0 0.0 2.8e-42 145.4 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEZ36307.1 - 1.9e-33 116.3 0.0 2.6e-32 112.6 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KEZ36307.1 - 2.7e-23 82.9 0.0 5.7e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KEZ36307.1 - 1.3e-11 44.9 0.3 1.1e-10 41.8 0.0 2.4 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily UvrD_C_2 PF13538.6 KEZ36307.1 - 3.5e-10 39.5 1.5 0.00081 19.2 1.2 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ36307.1 - 5.4e-06 26.3 6.7 0.00017 21.4 1.1 2.9 2 0 0 2 2 2 2 AAA domain Exo_endo_phos PF03372.23 KEZ36308.1 - 2e-14 53.7 0.6 2.9e-14 53.2 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_30 PF13556.6 KEZ36309.1 - 2.4e-17 62.5 0.5 6e-17 61.2 0.5 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 KEZ36309.1 - 0.0078 16.0 0.4 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 KEZ36309.1 - 0.03 14.2 0.2 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 KEZ36309.1 - 0.033 14.3 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KEZ36309.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AMP-binding_C PF13193.6 KEZ36309.1 - 0.11 13.4 0.8 0.3 12.1 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.21 KEZ36310.1 - 1.3e-23 84.0 0.0 1.9e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEZ36310.1 - 2.2e-18 66.7 0.0 3.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEZ36311.1 - 1.8e-19 70.5 0.0 3.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEZ36311.1 - 0.00027 20.9 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) ANTAR PF03861.14 KEZ36312.1 - 4.2e-16 58.5 3.6 7.7e-16 57.7 3.6 1.5 1 0 0 1 1 1 1 ANTAR domain GAF_2 PF13185.6 KEZ36312.1 - 3.8e-07 30.5 0.2 1.1e-06 29.0 0.2 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KEZ36312.1 - 1.6e-05 25.6 0.0 3.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain Glutaredoxin PF00462.24 KEZ36313.1 - 1.4e-14 54.0 0.0 1.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 KEZ36313.1 - 0.00055 20.2 0.0 0.00068 19.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 KEZ36313.1 - 0.00075 19.9 0.0 0.00077 19.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KEZ36313.1 - 0.002 18.6 0.3 0.031 14.7 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 KEZ36313.1 - 0.0025 18.2 0.0 0.0029 18.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 KEZ36313.1 - 0.0041 17.1 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KEZ36313.1 - 0.015 15.5 0.1 0.066 13.4 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like ThiP_synth PF10120.9 KEZ36313.1 - 0.064 12.9 0.0 0.071 12.7 0.0 1.0 1 0 0 1 1 1 0 Thiamine-phosphate synthase UvrD-helicase PF00580.21 KEZ36314.1 - 1.2e-45 156.4 0.0 1.6e-23 83.7 0.0 2.2 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEZ36314.1 - 2.5e-41 142.2 0.0 9.6e-25 87.7 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KEZ36314.1 - 4.5e-38 130.9 0.0 8.9e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain HRDC PF00570.23 KEZ36314.1 - 2.4e-22 78.7 0.0 5.6e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain UvrD_C_2 PF13538.6 KEZ36314.1 - 4.6e-12 45.6 1.7 1.5e-11 43.9 1.7 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ36314.1 - 1.9e-07 31.0 8.8 1.6e-05 24.7 1.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KEZ36314.1 - 0.00029 20.6 2.2 0.0077 16.0 0.1 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KEZ36314.1 - 0.024 14.3 0.0 0.21 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain HHH PF00633.23 KEZ36314.1 - 0.13 12.1 0.1 0.5 10.3 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-C4 PF00105.18 KEZ36314.1 - 0.17 12.3 0.4 0.34 11.4 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Gly-zipper_YMGG PF13441.6 KEZ36315.1 - 0.021 14.6 6.5 0.049 13.4 6.5 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Whib PF02467.16 KEZ36316.1 - 2.1e-16 60.2 0.1 3.1e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Transcription factor WhiB AT_hook PF02178.19 KEZ36316.1 - 0.22 11.5 7.9 0.41 10.7 7.9 1.5 1 0 0 1 1 1 0 AT hook motif Phosphodiest PF01663.22 KEZ36318.1 - 1.3e-29 103.9 0.1 1.7e-29 103.5 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEZ36318.1 - 0.0026 17.2 0.1 0.014 14.8 0.1 2.0 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KEZ36318.1 - 0.087 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ABC1 PF03109.16 KEZ36319.1 - 8.2e-29 100.2 0.0 1.2e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KEZ36319.1 - 7.8e-05 22.7 5.9 7.8e-05 22.7 5.9 2.9 3 1 0 3 3 3 1 Phosphotransferase enzyme family WXG100 PF06013.12 KEZ36319.1 - 0.2 11.9 0.3 17 5.7 0.0 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ThiF PF00899.21 KEZ36320.1 - 1.7e-09 37.4 1.0 5.2e-07 29.3 0.2 2.1 2 0 0 2 2 2 2 ThiF family 2-Hacid_dh_C PF02826.19 KEZ36320.1 - 0.069 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KEZ36320.1 - 0.13 11.5 1.3 0.21 10.8 1.3 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KEZ36320.1 - 0.22 11.8 0.5 0.83 9.9 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KEZ36320.1 - 0.28 11.0 0.4 0.47 10.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zincin_2 PF10103.9 KEZ36321.1 - 2.2e-122 408.5 7.9 2.5e-122 408.3 7.9 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase MoaE PF02391.17 KEZ36322.1 - 1.3e-35 122.0 1.0 1.6e-35 121.8 1.0 1.1 1 0 0 1 1 1 1 MoaE protein MAAL_N PF05034.13 KEZ36322.1 - 0.025 14.2 0.7 0.042 13.5 0.3 1.6 1 1 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus PDZ_2 PF13180.6 KEZ36324.1 - 7.6e-14 51.8 0.3 2.8e-13 50.0 0.1 2.1 2 0 0 2 2 2 1 PDZ domain Lon_C PF05362.13 KEZ36324.1 - 1.4e-09 37.8 1.2 3.2e-09 36.6 1.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain PDZ_6 PF17820.1 KEZ36324.1 - 6.5e-06 25.9 0.2 1.9e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEZ36324.1 - 3.1e-05 24.3 0.1 6.7e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain HlyD PF00529.20 KEZ36324.1 - 0.018 14.9 0.7 0.028 14.3 0.7 1.4 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS Tricorn_PDZ PF14685.6 KEZ36324.1 - 0.031 14.2 1.0 1.1 9.3 0.1 3.0 2 1 1 3 3 3 0 Tricorn protease PDZ domain UPF0182 PF03699.13 KEZ36326.1 - 8.5e-282 936.8 0.0 9.9e-282 936.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) ATP-synt_DE PF00401.20 KEZ36326.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HTH_AsnC-type PF13404.6 KEZ36328.1 - 1.9e-15 56.4 3.2 2e-15 56.3 1.6 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KEZ36328.1 - 1.5e-14 53.7 0.5 2.7e-14 52.9 0.5 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 KEZ36328.1 - 4.5e-11 42.1 0.4 1.4e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KEZ36328.1 - 0.00022 21.1 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 KEZ36328.1 - 0.00027 20.9 0.4 0.00092 19.2 0.2 1.9 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_28 PF13518.6 KEZ36328.1 - 0.0009 19.3 0.4 0.0015 18.6 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain NapD PF03927.13 KEZ36328.1 - 0.0022 18.0 0.3 0.0041 17.1 0.3 1.4 1 0 0 1 1 1 1 NapD protein Sigma70_r4_2 PF08281.12 KEZ36328.1 - 0.011 15.4 0.1 0.042 13.5 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.7 KEZ36328.1 - 0.036 13.9 0.4 0.083 12.8 0.4 1.6 1 0 0 1 1 1 0 MarR family PaaX PF07848.12 KEZ36328.1 - 0.064 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_Tnp_ISL3 PF13542.6 KEZ36328.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 KEZ36328.1 - 0.079 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.10 KEZ36328.1 - 0.4 10.5 0.2 0.4 10.5 0.2 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain Aminotran_3 PF00202.21 KEZ36329.1 - 3.6e-61 207.0 0.0 5.4e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEZ36329.1 - 5.1e-05 22.6 0.0 7.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aldedh PF00171.22 KEZ36330.1 - 8.4e-158 525.7 0.0 9.9e-158 525.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEZ36330.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) OmdA PF13376.6 KEZ36330.1 - 0.24 11.5 2.4 0.5 10.4 0.3 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Abhydrolase_1 PF00561.20 KEZ36331.1 - 1.1e-31 110.5 0.1 6.1e-31 108.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ36331.1 - 1.1e-22 81.7 14.8 1.6e-22 81.2 14.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ36331.1 - 1.6e-14 53.8 0.3 6e-14 51.9 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KEZ36331.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KEZ36331.1 - 0.0057 16.8 0.8 0.15 12.1 0.2 2.4 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_5 PF12695.7 KEZ36331.1 - 0.014 15.2 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KEZ36331.1 - 0.021 14.7 0.2 0.62 9.9 0.1 2.4 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_4 PF08386.10 KEZ36331.1 - 0.039 14.1 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 KEZ36331.1 - 0.052 13.1 0.0 3.5 7.1 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family Ndr PF03096.14 KEZ36331.1 - 0.072 11.8 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.16 KEZ36331.1 - 0.079 12.8 0.1 5.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KEZ36331.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2802 PF10975.8 KEZ36332.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) HTH_18 PF12833.7 KEZ36332.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 KEZ36332.1 - 0.036 13.9 0.0 0.42 10.5 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain LPD23 PF18838.1 KEZ36332.1 - 0.052 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 HTH_7 PF02796.15 KEZ36332.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GDPD PF03009.17 KEZ36333.1 - 9.7e-13 48.4 0.0 7.5e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Inositol_P PF00459.25 KEZ36334.1 - 1.2e-45 156.2 0.1 1.5e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RsgA_GTPase PF03193.16 KEZ36335.1 - 1.7e-43 148.4 0.0 3.9e-43 147.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KEZ36335.1 - 5.6e-08 32.9 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ36335.1 - 0.0011 19.4 0.1 0.002 18.5 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KEZ36335.1 - 0.0053 17.3 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KEZ36335.1 - 0.0053 17.0 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ36335.1 - 0.02 14.6 1.1 0.029 14.1 0.1 1.7 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KEZ36335.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KEZ36335.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KEZ36335.1 - 0.038 13.5 0.1 1.3 8.6 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KEZ36335.1 - 0.047 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEZ36335.1 - 0.051 13.5 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KEZ36335.1 - 0.079 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEZ36335.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 KEZ36335.1 - 0.1 12.6 0.1 3.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 KEZ36335.1 - 0.28 11.4 0.0 0.49 10.6 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EPSP_synthase PF00275.20 KEZ36336.1 - 1.3e-95 320.6 0.0 1.8e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Methyltransf_11 PF08241.12 KEZ36337.1 - 6.9e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ36337.1 - 2.9e-05 24.0 0.0 9.7e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ36337.1 - 0.00016 22.3 0.0 0.00033 21.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ36337.1 - 0.0051 17.5 0.0 0.0078 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PPS_PS PF02006.16 KEZ36337.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase Methyltransf_29 PF03141.16 KEZ36337.1 - 0.24 9.9 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Thioesterase PF00975.20 KEZ36338.1 - 3.9e-06 27.1 0.3 6e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KEZ36338.1 - 0.00023 21.9 12.1 0.0005 20.7 12.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ36338.1 - 0.001 18.4 0.3 1.1 8.4 0.2 2.9 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KEZ36338.1 - 0.029 13.9 1.1 0.13 11.8 1.1 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Sigma70_r2 PF04542.14 KEZ36339.1 - 5.3e-20 70.9 0.7 1.1e-19 70.0 0.7 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ36339.1 - 6.4e-16 57.8 0.0 2.2e-15 56.1 0.0 2.0 1 1 1 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ36339.1 - 2.8e-10 39.6 0.2 1.3e-09 37.4 0.0 2.3 3 1 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KEZ36339.1 - 0.00026 21.0 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 ECF sigma factor zf-HC2 PF13490.6 KEZ36340.1 - 3.5e-10 39.9 1.9 8.4e-10 38.7 1.9 1.7 1 0 0 1 1 1 1 Putative zinc-finger SMC_N PF02463.19 KEZ36342.1 - 1.5e-10 40.9 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ36342.1 - 2.3e-08 34.8 0.0 1.7e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain DivIC PF04977.15 KEZ36342.1 - 0.0019 17.9 0.1 0.76 9.6 0.0 2.8 2 0 0 2 2 2 2 Septum formation initiator AAA_21 PF13304.6 KEZ36342.1 - 0.0045 16.8 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEZ36342.1 - 0.0065 16.2 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ36342.1 - 0.066 13.5 2.0 0.45 10.8 0.3 3.0 3 1 0 3 3 3 0 AAA domain CTP_synth_N PF06418.14 KEZ36343.1 - 8.1e-121 402.3 0.0 1e-120 402.0 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KEZ36343.1 - 5e-47 160.1 0.0 8.1e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ36343.1 - 6.6e-07 29.3 0.1 2.3e-05 24.2 0.0 2.5 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 KEZ36343.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GATase_3 PF07685.14 KEZ36343.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NUDIX PF00293.28 KEZ36344.1 - 1.3e-12 47.9 0.3 1.8e-12 47.4 0.3 1.3 1 0 0 1 1 1 1 NUDIX domain PKD PF00801.20 KEZ36345.1 - 5.8e-06 26.1 0.1 2e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 PKD domain Phage_integrase PF00589.22 KEZ36347.1 - 5.7e-42 143.4 0.0 9e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ36347.1 - 6e-19 68.1 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF2303 PF10065.9 KEZ36348.1 - 0.038 13.1 0.0 0.043 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) F420_oxidored PF03807.17 KEZ36349.1 - 9.4e-19 67.8 0.1 2.2e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KEZ36349.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KEZ36349.1 - 0.043 14.0 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KEZ36349.1 - 0.068 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 KEZ36349.1 - 0.091 12.4 0.3 0.22 11.1 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Peripla_BP_2 PF01497.18 KEZ36350.1 - 1.8e-05 24.4 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Pantoate_transf PF02548.15 KEZ36351.1 - 6.1e-102 340.5 0.2 6.9e-102 340.3 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KEZ36351.1 - 0.00025 20.6 0.6 0.00047 19.7 0.6 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TetR_C_11 PF16859.5 KEZ36353.1 - 2.3e-30 105.2 0.4 4.9e-30 104.1 0.4 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ36353.1 - 1.1e-13 50.8 0.1 1.9e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 KEZ36353.1 - 0.00025 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain Sigma70_ECF PF07638.11 KEZ36353.1 - 0.031 14.2 0.0 0.074 12.9 0.0 1.6 2 0 0 2 2 2 0 ECF sigma factor HTH_31 PF13560.6 KEZ36353.1 - 0.34 11.3 4.2 32 5.0 3.0 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain tRNA-synt_2b PF00587.25 KEZ36354.1 - 6.9e-37 127.1 0.0 1.3e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEZ36354.1 - 7.8e-20 70.8 0.1 1.5e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KEZ36354.1 - 1.2e-12 47.7 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KEZ36354.1 - 0.014 15.4 0.9 0.043 13.9 0.9 1.8 1 1 0 1 1 1 0 TGS domain NAD_synthase PF02540.17 KEZ36355.1 - 9.6e-65 218.1 0.0 1.4e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 KEZ36355.1 - 1.2e-23 83.8 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.21 KEZ36355.1 - 0.0014 18.4 0.6 0.0022 17.7 0.6 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 KEZ36355.1 - 0.057 12.9 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Gln-synt_C PF00120.24 KEZ36356.1 - 8.3e-120 399.9 0.0 9.7e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KEZ36356.1 - 1e-26 92.5 0.0 2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 KEZ36356.1 - 0.00013 21.8 0.0 0.0014 18.4 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain GlnE PF03710.15 KEZ36357.1 - 5.5e-93 311.0 3.9 4e-46 157.5 0.1 2.5 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 KEZ36357.1 - 9.8e-55 184.7 3.7 2.3e-37 128.3 4.1 2.5 2 0 0 2 2 2 2 GlnD PII-uridylyltransferase DUF294_C PF10335.9 KEZ36357.1 - 1.2e-05 25.1 1.4 0.053 13.3 0.9 2.7 2 0 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain DUF294 PF03445.13 KEZ36357.1 - 0.00018 21.3 0.0 0.096 12.5 0.0 2.8 2 0 0 2 2 2 2 Putative nucleotidyltransferase DUF294 Gln-synt_C PF00120.24 KEZ36358.1 - 6.3e-22 78.0 0.0 3.7e-13 49.2 0.0 2.4 1 1 2 3 3 3 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KEZ36358.1 - 5.5e-14 51.7 0.0 9.6e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 KEZ36360.1 - 8.9e-139 462.3 0.0 1e-138 462.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KEZ36360.1 - 1.2e-28 98.7 0.3 2.4e-28 97.7 0.3 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RDD PF06271.12 KEZ36361.1 - 3.6e-09 36.9 11.4 4e-08 33.6 11.4 2.3 1 1 0 1 1 1 1 RDD family DUF805 PF05656.14 KEZ36361.1 - 0.21 12.0 2.5 0.31 11.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3082 PF11282.8 KEZ36361.1 - 1.3 9.3 5.8 1 9.7 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) DUF4191 PF13829.6 KEZ36362.1 - 9.1e-73 244.2 0.6 1.2e-72 243.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) DUF4083 PF13314.6 KEZ36362.1 - 0.33 10.9 0.8 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) LapA_dom PF06305.11 KEZ36362.1 - 4.2 7.2 6.8 1.4 8.8 1.4 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Radical_SAM PF04055.21 KEZ36364.1 - 2.6e-13 50.7 0.0 4.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 KEZ36364.1 - 8.4e-07 29.4 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Peptidase_S51 PF03575.17 KEZ36365.1 - 1.5e-30 106.4 0.0 1.6e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 Pkinase PF00069.25 KEZ36366.1 - 7e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36366.1 - 7.1e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 2-oxoacid_dh PF00198.23 KEZ36367.1 - 1.7e-69 233.8 0.0 2.5e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ36367.1 - 7e-22 77.1 1.8 1.5e-21 76.0 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEZ36367.1 - 2.1e-15 56.8 0.2 2.1e-15 56.8 0.2 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KEZ36367.1 - 0.00018 21.3 0.3 0.56 10.1 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KEZ36367.1 - 0.001 19.7 2.4 0.83 10.4 0.5 2.9 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 KEZ36367.1 - 0.018 14.3 0.1 0.58 9.3 0.1 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KEZ36367.1 - 0.12 12.3 0.4 0.25 11.2 0.4 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Pyr_redox_2 PF07992.14 KEZ36368.1 - 1.1e-61 208.7 1.0 1.3e-61 208.4 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEZ36368.1 - 4.7e-26 91.2 0.2 1e-25 90.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEZ36368.1 - 1.2e-19 70.7 0.7 1.1e-17 64.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ36368.1 - 7.6e-09 35.1 2.0 3.6e-07 29.6 0.8 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KEZ36368.1 - 8.1e-09 35.2 0.1 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ36368.1 - 1.7e-08 34.3 0.9 2.6e-07 30.4 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ36368.1 - 1.3e-07 30.7 6.1 0.011 14.4 0.3 3.3 2 1 1 3 3 3 3 HI0933-like protein NAD_binding_8 PF13450.6 KEZ36368.1 - 1.9e-06 28.0 3.0 0.012 15.9 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ36368.1 - 7.9e-06 25.2 1.4 6.3e-05 22.2 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEZ36368.1 - 0.00011 21.6 0.8 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KEZ36368.1 - 0.00066 19.4 12.9 0.039 13.5 1.3 4.1 3 1 0 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KEZ36368.1 - 0.001 19.0 0.2 0.0059 16.5 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KEZ36368.1 - 0.0012 17.9 6.2 0.42 9.6 0.7 3.6 3 1 1 4 4 4 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KEZ36368.1 - 0.0026 16.7 0.1 0.038 12.9 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KEZ36368.1 - 0.038 13.2 1.7 0.049 12.9 0.2 1.9 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 KEZ36368.1 - 0.061 12.7 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain T2SS-T3SS_pil_N PF13629.6 KEZ36368.1 - 0.096 12.4 1.5 0.15 11.8 0.1 2.1 3 0 0 3 3 2 0 Pilus formation protein N terminal region Amino_oxidase PF01593.24 KEZ36368.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KEZ36368.1 - 0.2 11.6 2.2 6.3 6.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KEZ36368.1 - 0.44 9.8 4.4 6.5 5.9 0.1 3.0 2 1 1 3 3 3 0 FAD binding domain Peptidase_M17 PF00883.21 KEZ36369.1 - 1.3e-110 369.6 0.0 1.8e-110 369.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KEZ36369.1 - 1.6e-23 83.0 2.7 3.5e-23 81.8 2.7 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Multi_ubiq PF14452.6 KEZ36369.1 - 0.11 12.8 0.3 6.8 7.0 0.1 2.7 2 0 0 2 2 2 0 Multiubiquitin GCV_T PF01571.21 KEZ36370.1 - 1.2e-81 273.9 0.0 1.4e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KEZ36370.1 - 2.2e-16 59.6 0.1 5e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CobS PF02654.15 KEZ36371.1 - 8.7e-42 143.6 24.4 1e-41 143.4 24.4 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DUF4389 PF14333.6 KEZ36371.1 - 0.03 14.2 0.9 0.55 10.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DBI_PRT PF02277.17 KEZ36372.1 - 3.4e-132 440.7 10.4 3.9e-132 440.5 10.4 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase WD40 PF00400.32 KEZ36373.1 - 0.00014 22.5 0.7 0.00027 21.7 0.3 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat CobU PF02283.16 KEZ36374.1 - 2.5e-48 163.9 0.0 3.6e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Lactamase_B PF00753.27 KEZ36374.1 - 1e-07 32.2 0.1 3e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ36374.1 - 2.6e-06 27.1 0.1 1.7e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Phage_holin_3_6 PF07332.11 KEZ36375.1 - 0.0011 19.0 1.2 0.0011 19.0 1.2 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Ion_trans PF00520.31 KEZ36375.1 - 0.029 13.6 0.1 0.031 13.5 0.1 1.0 1 0 0 1 1 1 0 Ion transport protein F420H2_quin_red PF04075.14 KEZ36377.1 - 2.5e-06 27.7 0.1 3.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase TetR_C_33 PF13305.6 KEZ36378.1 - 7.2e-10 39.5 4.9 3.6e-08 34.1 4.3 2.7 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ36378.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Aldo_ket_red PF00248.21 KEZ36379.1 - 2e-70 237.3 0.0 2.3e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3043 PF11241.8 KEZ36380.1 - 8.2e-50 169.2 8.1 9.8e-50 168.9 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) DinI PF06183.13 KEZ36380.1 - 0.01 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 DinI-like family NadA PF02445.16 KEZ36381.1 - 2.3e-103 345.5 0.0 3.6e-103 344.8 0.0 1.3 1 1 0 1 1 1 1 Quinolinate synthetase A protein Fe-S_biosyn PF01521.20 KEZ36382.1 - 1.5e-20 73.5 0.0 1.8e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PfkB PF00294.24 KEZ36383.1 - 2.7e-40 138.5 0.0 3.4e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TusA PF01206.17 KEZ36384.1 - 3.8e-08 33.0 0.0 4.1e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA Aminotran_5 PF00266.19 KEZ36385.1 - 8.3e-51 173.1 0.1 2.5e-50 171.5 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ36385.1 - 0.0005 19.5 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KEZ36385.1 - 0.083 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein COX2 PF00116.20 KEZ36386.1 - 3.4e-21 75.3 0.1 8.8e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 KEZ36386.1 - 5.7e-06 26.4 0.1 9.8e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF2569 PF10754.9 KEZ36386.1 - 0.0016 18.9 0.1 0.0025 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) Bestrophin PF01062.21 KEZ36386.1 - 0.033 13.6 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Cupredoxin_1 PF13473.6 KEZ36386.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain COX1 PF00115.20 KEZ36387.1 - 2.8e-149 497.7 61.7 3.2e-149 497.5 61.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cyt_c_ox_IV PF12270.8 KEZ36388.1 - 1.5e-40 138.4 6.0 1.8e-40 138.1 6.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Phage_holin_3_6 PF07332.11 KEZ36388.1 - 0.0098 15.9 0.2 0.0098 15.9 0.2 2.1 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III PRA1 PF03208.19 KEZ36388.1 - 0.038 13.6 1.6 0.1 12.2 1.6 1.7 1 1 0 1 1 1 0 PRA1 family protein CYYR1 PF10873.8 KEZ36388.1 - 0.068 13.6 2.1 0.13 12.7 2.1 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF308 PF03729.13 KEZ36388.1 - 1.4 9.3 19.5 0.72 10.2 4.7 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) UPF0715 PF17094.5 KEZ36388.1 - 1.5 9.4 6.8 5.8 7.5 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0715) DUF4131 PF13567.6 KEZ36388.1 - 4.4 6.9 6.9 2.5 7.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glycos_transf_3 PF00591.21 KEZ36389.1 - 8.4e-77 258.2 1.9 1.1e-76 257.8 1.9 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KEZ36389.1 - 1e-13 50.9 0.4 1e-13 50.9 0.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain Response_reg PF00072.24 KEZ36390.1 - 1.8e-05 24.9 0.0 2.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain FUR PF01475.19 KEZ36391.1 - 6.5e-23 81.2 0.0 7.3e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family Rubrerythrin PF02915.17 KEZ36392.1 - 6.4e-27 94.6 0.4 1.8e-26 93.2 0.4 1.6 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 KEZ36392.1 - 4.4e-07 29.9 0.2 3.7e-05 23.7 0.2 2.0 1 1 0 1 1 1 1 Ferritin-like domain DUF3501 PF12007.8 KEZ36393.1 - 1e-60 205.0 0.1 1.1e-60 204.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3501) Peptidase_S24 PF00717.23 KEZ36393.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase S24-like SseB PF07179.12 KEZ36394.1 - 8.2e-14 52.0 0.0 1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 SseB protein N-terminal domain COX3 PF00510.18 KEZ36395.1 - 1.1e-24 87.7 13.2 1.3e-24 87.4 13.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Cytochrome_CBB3 PF13442.6 KEZ36396.1 - 1.9e-23 82.5 0.2 3.9e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KEZ36396.1 - 1.7e-14 54.7 7.8 6.9e-06 27.1 1.0 3.9 2 2 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 KEZ36396.1 - 3.4e-07 30.1 0.6 0.084 12.6 0.1 3.1 2 1 1 3 3 3 2 Cytochrome c-550 domain Cytochrom_C1 PF02167.15 KEZ36396.1 - 0.018 14.8 0.6 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C1 family Cytochrome_C7 PF14522.6 KEZ36396.1 - 0.036 14.1 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c MCR PF18509.1 KEZ36396.1 - 0.046 13.3 3.2 0.56 9.8 0.3 2.5 2 0 0 2 2 2 0 Magnetochrome domain Paired_CXXCH_1 PF09699.10 KEZ36396.1 - 0.065 13.0 0.3 8.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) CCP_MauG PF03150.14 KEZ36396.1 - 0.093 13.4 3.2 14 6.3 0.1 2.8 1 1 2 3 3 3 0 Di-haem cytochrome c peroxidase CpXC PF14353.6 KEZ36396.1 - 0.2 11.7 0.0 16 5.6 0.0 2.2 2 0 0 2 2 2 0 CpXC protein DHOR PF06537.11 KEZ36396.1 - 0.21 10.2 0.5 1.7 7.2 0.0 1.9 1 1 1 2 2 2 0 Di-haem oxidoreductase, putative peroxidase Rieske PF00355.26 KEZ36397.1 - 1.1e-09 38.0 0.2 2.1e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2530 PF10745.9 KEZ36397.1 - 0.083 13.1 0.4 0.2 11.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Cytochrom_B_N_2 PF13631.6 KEZ36398.1 - 1.3e-58 197.8 6.6 1.3e-58 197.8 6.6 1.8 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 KEZ36398.1 - 2.6e-26 92.6 10.3 1.6e-24 86.8 10.3 2.3 1 1 0 1 1 1 1 Cytochrome b/b6/petB DUF4405 PF14358.6 KEZ36398.1 - 0.0068 16.9 8.4 0.0068 16.9 8.4 3.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4405) RNase_T PF00929.24 KEZ36399.1 - 1.9e-31 109.9 0.0 2.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KEZ36399.1 - 5.7e-06 26.4 0.0 0.00061 19.8 0.0 2.2 2 0 0 2 2 2 2 3' exoribonuclease, RNase T-like GIY-YIG PF01541.24 KEZ36399.1 - 2.6e-05 24.4 0.0 5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain RNase_H_2 PF13482.6 KEZ36399.1 - 0.025 14.6 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 RNase_H superfamily Glyoxalase_6 PF18029.1 KEZ36400.1 - 3.4e-23 82.5 0.1 4e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KEZ36400.1 - 0.056 13.6 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HIT PF01230.23 KEZ36401.1 - 5.5e-19 68.7 0.0 7.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEZ36401.1 - 1.8e-08 34.9 0.0 2.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4352 PF11611.8 KEZ36402.1 - 2.7e-10 40.6 0.0 4.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) NYN_YacP PF05991.11 KEZ36403.1 - 6.1e-17 62.1 0.0 4.3e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 YacP-like NYN domain CENP-Q PF13094.6 KEZ36403.1 - 0.00046 20.4 8.9 0.0007 19.8 8.9 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Golgin_A5 PF09787.9 KEZ36403.1 - 0.007 15.9 8.7 0.0098 15.4 8.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lebercilin PF15619.6 KEZ36403.1 - 0.14 11.8 11.5 0.21 11.2 11.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Takusan PF04822.13 KEZ36403.1 - 0.28 11.1 1.0 0.56 10.1 1.0 1.4 1 0 0 1 1 1 0 Takusan ERM PF00769.19 KEZ36403.1 - 2.8 7.7 21.0 4.4 7.1 21.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 KEZ36403.1 - 3.5 7.7 23.4 0.61 10.2 11.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KEZ36403.1 - 3.7 6.8 20.2 5.3 6.3 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KEZ36403.1 - 6.2 5.3 6.2 10 4.7 6.2 1.2 1 0 0 1 1 1 0 AAA domain TEX13 PF15186.6 KEZ36403.1 - 6.5 6.4 11.6 3.6 7.2 9.5 1.6 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Glycos_transf_1 PF00534.20 KEZ36405.1 - 2.8e-35 121.4 0.0 3.6e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ36405.1 - 4.1e-27 95.2 0.1 6.3e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ36405.1 - 3.9e-10 40.0 0.0 8.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ36405.1 - 1.9e-08 34.5 1.2 7e-08 32.6 0.8 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 AMP-binding PF00501.28 KEZ36406.1 - 3.2e-94 315.9 0.0 5e-94 315.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ36406.1 - 0.13 13.3 0.0 0.38 11.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Metallophos_2 PF12850.7 KEZ36407.1 - 1.7e-09 38.0 0.0 1.3e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KEZ36407.1 - 2.5e-09 37.9 0.0 4.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Polyketide_cyc2 PF10604.9 KEZ36408.1 - 1.8e-11 44.5 0.1 2.2e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KEZ36408.1 - 5.6e-10 39.5 0.0 6.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ArsA_ATPase PF02374.15 KEZ36409.1 - 1.3e-48 165.8 0.0 1.5e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase ArsA_HSP20 PF17886.1 KEZ36409.1 - 5.4e-20 70.7 0.0 1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CbiA PF01656.23 KEZ36409.1 - 5.9e-05 23.1 0.0 9.6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEZ36409.1 - 0.00029 20.8 0.1 0.0016 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 KEZ36409.1 - 0.024 13.6 0.7 0.039 12.9 0.7 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Methyltransf_24 PF13578.6 KEZ36409.1 - 0.031 15.3 0.0 0.44 11.6 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain ParA PF10609.9 KEZ36409.1 - 0.07 12.6 0.2 0.31 10.5 0.2 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KEZ36409.1 - 0.28 10.6 0.1 0.49 9.8 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF5304 PF17230.2 KEZ36410.1 - 0.013 15.7 0.2 0.04 14.2 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5304) ROK PF00480.20 KEZ36411.1 - 3.7e-79 266.3 0.1 4.2e-79 266.1 0.1 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 KEZ36411.1 - 0.036 13.6 0.8 0.1 12.1 0.3 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KEZ36411.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.4 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Saccharop_dh_N PF04455.12 KEZ36412.1 - 8.1e-26 90.4 0.0 1.6e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region Hydrolase_4 PF12146.8 KEZ36414.1 - 1.9e-13 50.2 0.0 3.4e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ36414.1 - 1.8e-12 48.4 9.6 2.4e-12 47.9 9.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ36414.1 - 1.1e-09 38.4 0.1 4.2e-09 36.4 0.2 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ36414.1 - 0.0021 17.6 0.0 0.0071 15.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ36414.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KEZ36414.1 - 0.017 15.1 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 KEZ36414.1 - 0.032 14.2 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 KEZ36414.1 - 0.047 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KEZ36414.1 - 0.065 12.9 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Acyltransferase PF01553.21 KEZ36415.1 - 1.1e-24 86.5 0.0 1.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Sporozoite_P67 PF05642.11 KEZ36415.1 - 0.0095 14.1 0.2 0.0097 14.1 0.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF374 PF04028.13 KEZ36415.1 - 0.021 14.4 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Glyco_hydro_5_C PF18564.1 KEZ36416.1 - 5.7e-12 46.0 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain DUF5051 PF16473.5 KEZ36417.1 - 1.2e-15 57.9 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like PFK PF00365.20 KEZ36418.1 - 5e-97 324.6 0.1 5.7e-97 324.5 0.1 1.0 1 0 0 1 1 1 1 Phosphofructokinase DAHP_synth_2 PF01474.16 KEZ36419.1 - 1.2e-189 630.3 0.0 1.4e-189 630.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF4277 PF14104.6 KEZ36420.1 - 3.5e-15 56.3 0.0 5.3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4277) Aminotran_4 PF01063.19 KEZ36422.1 - 1.8e-31 109.8 0.0 2.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HTH_31 PF13560.6 KEZ36423.1 - 9.9e-10 38.6 0.1 1.3e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ36423.1 - 8.4e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ36423.1 - 7.2e-06 25.9 0.0 9.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ36423.1 - 0.0021 17.8 0.2 0.0085 15.9 0.1 2.0 2 1 0 2 2 2 1 Homeodomain-like domain YdaS_antitoxin PF15943.5 KEZ36423.1 - 0.0023 17.8 0.1 0.0051 16.6 0.0 1.8 1 1 1 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 KEZ36423.1 - 0.0061 16.4 0.1 0.088 12.6 0.0 2.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_25 PF13413.6 KEZ36423.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 KEZ36423.1 - 0.026 14.4 0.1 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 KEZ36423.1 - 0.056 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 KEZ36423.1 - 0.13 12.7 0.1 0.18 12.3 0.1 1.4 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Nterm_IS4 PF13006.7 KEZ36424.1 - 3.8e-27 94.3 0.5 2.7e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 Insertion element 4 transposase N-terminal DDE_Tnp_1_2 PF13586.6 KEZ36425.1 - 4e-12 46.3 0.0 5.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ36425.1 - 0.0008 19.1 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain TP2 PF01254.18 KEZ36425.1 - 0.0091 16.6 0.7 0.011 16.3 0.7 1.1 1 0 0 1 1 1 1 Nuclear transition protein 2 DDE_Tnp_4 PF13359.6 KEZ36425.1 - 0.063 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Helicase_C PF00271.31 KEZ36426.1 - 2.5e-05 24.6 0.1 4.6e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 KEZ36427.1 - 1.4e-09 38.5 0.2 3.3e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) zinc_ribbon_4 PF13717.6 KEZ36427.1 - 0.2 11.6 0.9 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain N6_Mtase PF02384.16 KEZ36428.1 - 2.8e-24 86.0 0.0 4.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 KEZ36428.1 - 0.0026 18.4 0.2 0.016 15.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain HTH_23 PF13384.6 KEZ36428.1 - 0.01 15.6 0.0 0.039 13.8 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KEZ36428.1 - 0.029 14.5 0.2 0.12 12.5 0.2 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.21 KEZ36428.1 - 0.033 14.0 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MTS PF05175.14 KEZ36428.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KEZ36428.1 - 0.15 12.7 0.1 0.66 10.7 0.1 2.1 1 0 0 1 1 1 0 Methyltransferase domain Phage_antiter_Q PF06323.11 KEZ36428.1 - 0.26 10.8 0.0 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q Pkinase PF00069.25 KEZ36429.1 - 2.5e-41 141.8 0.0 3.8e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36429.1 - 3.5e-27 95.3 0.0 5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ36429.1 - 2.8e-08 34.0 3.4 9.1e-07 29.0 0.1 3.6 2 2 1 3 3 3 2 Phosphotransferase enzyme family TPR_12 PF13424.6 KEZ36429.1 - 0.0004 20.6 10.9 0.013 15.7 3.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Kdo PF06293.14 KEZ36429.1 - 0.00095 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ36429.1 - 0.0022 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KEZ36429.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TPR_20 PF14561.6 KEZ36429.1 - 0.0045 17.3 1.1 1.9 8.8 0.4 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ36429.1 - 0.21 12.3 11.8 2.1 9.1 9.2 3.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ36429.1 - 0.4 11.2 7.0 0.71 10.4 1.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF402 PF04167.13 KEZ36430.1 - 2.2e-15 56.6 2.1 3.9e-15 55.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF402) Putative_PNPOx PF01243.20 KEZ36431.1 - 1.5e-14 53.9 0.3 3.6e-14 52.7 0.3 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KEZ36431.1 - 0.0005 20.1 0.5 0.0011 19.0 0.5 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABC_tran PF00005.27 KEZ36432.1 - 4.7e-36 124.3 0.0 1.2e-22 80.9 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEZ36432.1 - 2.7e-12 47.1 2.4 0.00061 19.7 0.0 4.1 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ36432.1 - 5e-08 32.7 0.0 0.99 8.8 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ36432.1 - 8.4e-08 31.8 1.5 0.0056 16.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ36432.1 - 2.1e-07 31.7 0.3 0.03 14.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEZ36432.1 - 2.3e-05 24.7 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEZ36432.1 - 8.3e-05 22.5 0.3 0.045 13.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KEZ36432.1 - 9.3e-05 22.7 5.8 0.066 13.5 0.2 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KEZ36432.1 - 0.00011 22.2 0.4 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ36432.1 - 0.00016 22.1 10.0 0.0048 17.3 0.5 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KEZ36432.1 - 0.00026 21.5 0.7 0.82 10.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain Collagen PF01391.18 KEZ36432.1 - 0.00028 20.6 2.9 0.00095 18.9 2.9 1.9 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ABC_tran_Xtn PF12848.7 KEZ36432.1 - 0.00045 20.2 10.1 0.0027 17.7 10.1 2.0 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 KEZ36432.1 - 0.00087 19.2 0.5 0.87 9.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 KEZ36432.1 - 0.00089 18.9 3.2 0.87 9.1 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_27 PF13514.6 KEZ36432.1 - 0.0014 18.3 1.3 1.5 8.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KEZ36432.1 - 0.0015 19.0 1.3 0.29 11.6 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KEZ36432.1 - 0.0019 18.2 0.4 1.1 9.2 0.1 2.5 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KEZ36432.1 - 0.0033 17.2 10.4 0.037 13.7 0.5 3.3 3 1 0 3 3 2 2 AAA domain cobW PF02492.19 KEZ36432.1 - 0.0042 16.7 1.1 0.66 9.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KEZ36432.1 - 0.0049 17.2 0.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KEZ36432.1 - 0.0049 17.0 2.5 0.24 11.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KEZ36432.1 - 0.0084 15.9 0.1 3.8 7.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEZ36432.1 - 0.0099 15.0 3.0 0.19 10.7 1.1 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KEZ36432.1 - 0.016 15.0 0.6 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KEZ36432.1 - 0.021 14.9 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family SRP54 PF00448.22 KEZ36432.1 - 0.023 14.3 0.5 4 7.0 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 KEZ36432.1 - 0.027 14.5 0.2 5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KEZ36432.1 - 0.029 14.2 0.2 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 KEZ36432.1 - 0.039 13.7 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KEZ36432.1 - 0.042 12.8 3.5 0.34 9.8 0.6 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 KEZ36432.1 - 0.044 13.7 0.0 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KEZ36432.1 - 0.068 12.5 0.6 8.5 5.7 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KEZ36432.1 - 0.082 12.4 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KEZ36432.1 - 0.11 12.7 0.2 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KEZ36432.1 - 0.14 12.1 0.0 18 5.1 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KEZ36432.1 - 0.14 11.8 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 KEZ36432.1 - 0.21 10.4 0.8 3.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MutS_V PF00488.21 KEZ36432.1 - 0.22 11.5 1.2 16 5.4 0.2 2.4 2 0 0 2 2 2 0 MutS domain V AAA_5 PF07728.14 KEZ36432.1 - 0.27 11.2 6.1 6.4 6.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 KEZ36432.1 - 0.54 7.7 6.8 5.3 4.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Herpes_capsid PF06112.11 KEZ36432.1 - 1.5 8.9 5.5 4.4 7.4 5.5 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3466 PF11949.8 KEZ36433.1 - 0.092 11.3 4.2 0.48 9.0 0.3 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3466) AAA_33 PF13671.6 KEZ36434.1 - 7.4e-05 22.9 0.2 0.00013 22.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ36434.1 - 0.00011 22.7 0.0 0.00021 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KEZ36434.1 - 0.00065 19.9 0.0 0.0024 18.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase IPT PF01745.16 KEZ36434.1 - 0.00076 18.9 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase AAA_16 PF13191.6 KEZ36434.1 - 0.0012 19.3 0.1 0.002 18.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KEZ36434.1 - 0.0019 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 KEZ36434.1 - 0.0021 18.3 0.1 0.0059 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ36434.1 - 0.0034 17.8 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ36434.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KEZ36434.1 - 0.018 14.8 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 KEZ36434.1 - 0.024 13.8 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KEZ36434.1 - 0.026 15.0 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KEZ36434.1 - 0.038 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEZ36434.1 - 0.044 14.2 0.0 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KEZ36434.1 - 0.071 12.7 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KEZ36434.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KEZ36434.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KEZ36434.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KEZ36434.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KEZ36434.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KEZ36434.1 - 0.14 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KEZ36434.1 - 0.21 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 KEZ36434.1 - 0.21 12.0 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 KEZ36434.1 - 0.25 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 KEZ36434.1 - 0.32 10.1 0.0 0.42 9.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit THF_DHG_CYH_C PF02882.19 KEZ36435.1 - 2e-61 206.0 1.0 3.2e-61 205.3 1.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KEZ36435.1 - 4.7e-32 110.7 0.0 6.5e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Carmo_coat_C PF08462.10 KEZ36435.1 - 0.056 13.6 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Carmovirus coat protein MMPL PF03176.15 KEZ36436.1 - 3.7e-98 328.5 37.6 1.7e-50 171.8 10.5 2.2 2 0 0 2 2 2 2 MMPL family FixQ PF05545.11 KEZ36436.1 - 1.5 8.9 4.1 1.9 8.5 0.2 3.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ACR_tran PF00873.19 KEZ36436.1 - 3.3 5.2 21.2 0.0048 14.6 1.6 2.3 2 1 0 2 2 2 0 AcrB/AcrD/AcrF family p450 PF00067.22 KEZ36438.1 - 2.1e-65 221.3 0.0 3e-64 217.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 cobW PF02492.19 KEZ36439.1 - 4.2e-33 114.4 0.0 5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KEZ36439.1 - 0.00035 19.6 4.1 0.02 13.9 0.4 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KEZ36439.1 - 0.001 19.5 0.1 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 KEZ36439.1 - 0.034 14.2 0.1 0.054 13.6 0.0 1.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KEZ36439.1 - 0.037 14.6 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ36439.1 - 0.07 13.6 0.0 0.095 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEZ36439.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KEZ36439.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 KEZ36439.1 - 0.11 12.6 0.1 0.43 10.7 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.13 KEZ36439.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KEZ36439.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KEZ36439.1 - 0.12 12.2 0.2 0.8 9.6 0.2 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KEZ36439.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_26 PF13500.6 KEZ36439.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ36439.1 - 0.21 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Peptidase_M22 PF00814.25 KEZ36440.1 - 8.3e-86 288.0 0.4 9.6e-86 287.8 0.4 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KEZ36440.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus FUR PF01475.19 KEZ36441.1 - 1.7e-20 73.3 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_IclR PF09339.10 KEZ36441.1 - 0.0007 19.3 0.4 0.0033 17.2 0.4 2.1 1 1 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 KEZ36441.1 - 0.0086 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB zinc_ribbon_4 PF13717.6 KEZ36441.1 - 0.015 15.2 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain HTH_20 PF12840.7 KEZ36441.1 - 0.058 13.5 0.2 0.22 11.6 0.2 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain Rubredoxin_2 PF18073.1 KEZ36441.1 - 0.26 11.0 1.8 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_S27e PF01667.17 KEZ36441.1 - 0.48 10.2 1.8 2.6 7.8 0.1 2.6 3 0 0 3 3 3 0 Ribosomal protein S27 Pep_deformylase PF01327.21 KEZ36442.1 - 1.3e-43 148.3 0.0 1.5e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Bac_luciferase PF00296.20 KEZ36443.1 - 7.5e-40 137.3 9.7 3.6e-39 135.1 9.7 2.0 1 1 0 1 1 1 1 Luciferase-like monooxygenase HAD PF12710.7 KEZ36443.1 - 0.11 12.9 0.6 7.3 7.0 0.1 2.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase FAD-oxidase_C PF02913.19 KEZ36444.1 - 5e-36 124.6 0.0 7.3e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ36444.1 - 1.1e-35 122.4 0.4 2e-35 121.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain TP_methylase PF00590.20 KEZ36445.1 - 1.6e-27 96.8 0.2 2.1e-27 96.5 0.2 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MmgE_PrpD PF03972.14 KEZ36446.1 - 4.3e-123 411.1 9.8 5e-123 410.9 9.8 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PEP_mutase PF13714.6 KEZ36447.1 - 5.8e-51 173.3 4.8 6.9e-51 173.0 4.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KEZ36447.1 - 9e-12 44.2 0.6 1.3e-11 43.7 0.6 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Peptidase_M20 PF01546.28 KEZ36448.1 - 1.1e-37 129.8 0.0 1.8e-37 129.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ36448.1 - 8.4e-16 57.9 0.1 2.3e-15 56.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ36448.1 - 7.8e-08 32.2 0.0 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 MbtH PF03621.13 KEZ36449.1 - 0.081 12.4 0.2 12 5.4 0.1 2.2 2 0 0 2 2 2 0 MbtH-like protein Mannosyl_trans2 PF04188.13 KEZ36451.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 KEZ36452.1 - 7.7e-17 62.0 11.7 7.7e-17 62.0 11.7 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_transf_22 PF03901.17 KEZ36452.1 - 0.0085 15.4 3.3 0.016 14.5 3.3 1.5 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Collagen PF01391.18 KEZ36452.1 - 1.6 8.5 12.6 3.4 7.5 12.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) NAD_binding_8 PF13450.6 KEZ36454.1 - 7.8e-13 48.5 0.0 2.1e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEZ36454.1 - 1.5e-09 37.7 0.2 1.3e-08 34.6 0.2 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEZ36454.1 - 9.6e-07 28.7 6.8 3.7e-05 23.5 6.8 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ36454.1 - 9.2e-06 25.1 0.1 1.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KEZ36454.1 - 1.1e-05 24.8 0.5 2.7e-05 23.4 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ36454.1 - 8.6e-05 21.9 0.2 0.00017 20.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ36454.1 - 0.00011 21.6 0.2 0.00022 20.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ36454.1 - 0.00028 19.7 0.3 0.0006 18.6 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KEZ36454.1 - 0.00043 19.6 0.5 0.00073 18.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KEZ36454.1 - 0.00092 19.7 1.2 0.53 10.9 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ36454.1 - 0.00094 18.6 1.2 0.0043 16.4 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ36454.1 - 0.0016 17.6 0.2 0.003 16.7 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEZ36454.1 - 0.0039 17.2 0.3 0.021 14.8 0.3 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ36454.1 - 0.02 13.9 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein PMT_2 PF13231.6 KEZ36456.1 - 1.5e-10 41.5 17.7 1.5e-10 41.5 17.7 3.6 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PTPS_related PF10131.9 KEZ36456.1 - 0.02 13.2 11.7 0.032 12.5 11.7 1.3 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Trep_Strep PF09605.10 KEZ36456.1 - 8.1 6.4 15.6 0.83 9.6 9.3 2.4 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) AAA_30 PF13604.6 KEZ36457.1 - 6.2e-44 150.0 1.2 1.4e-43 148.9 1.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ36457.1 - 1.5e-30 106.5 0.0 2.8e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KEZ36457.1 - 1.9e-17 62.8 0.2 4.6e-17 61.6 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HHH_4 PF14490.6 KEZ36457.1 - 6.2e-11 42.1 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix containing domain AAA_11 PF13086.6 KEZ36457.1 - 5.4e-08 32.9 0.3 0.0091 15.8 0.3 2.2 1 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ36457.1 - 1.7e-07 31.2 0.0 0.023 14.5 0.0 2.4 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SH3_13 PF18335.1 KEZ36457.1 - 2.7e-06 27.1 0.0 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain Helicase_RecD PF05127.14 KEZ36457.1 - 2.9e-05 24.0 3.6 0.00018 21.4 3.6 2.1 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.6 KEZ36457.1 - 0.00091 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ36457.1 - 0.0021 18.4 0.9 0.0021 18.4 0.9 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF4350 PF14258.6 KEZ36457.1 - 0.076 13.5 2.1 62 4.1 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) PIF1 PF05970.14 KEZ36457.1 - 0.18 11.0 0.1 0.33 10.1 0.1 1.4 1 1 0 1 1 1 0 PIF1-like helicase UvrD_C PF13361.6 KEZ36457.1 - 0.22 10.9 0.0 0.39 10.0 0.0 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain His_Phos_1 PF00300.22 KEZ36458.1 - 1.6e-46 158.5 0.1 2e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3090 PF11290.8 KEZ36459.1 - 9.6e-59 198.0 0.0 1.1e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3090) Rad50_zn_hook PF04423.14 KEZ36459.1 - 0.00055 19.7 0.5 0.00081 19.2 0.1 1.5 2 0 0 2 2 2 1 Rad50 zinc hook motif PI3_PI4_kinase PF00454.27 KEZ36461.1 - 0.0053 16.6 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_1e PF01406.19 KEZ36462.1 - 3.3e-83 279.5 0.0 4.2e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KEZ36462.1 - 1.6e-07 30.4 0.0 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEZ36462.1 - 2e-05 23.1 0.0 0.00029 19.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KEZ36462.1 - 0.081 11.8 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) DivIVA PF05103.13 KEZ36463.1 - 1.6e-06 28.2 3.6 2.2e-05 24.6 3.6 2.3 1 1 0 1 1 1 1 DivIVA protein Effector_1 PF04518.12 KEZ36463.1 - 0.11 11.5 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Effector from type III secretion system PAC2 PF09754.9 KEZ36464.1 - 5.3e-52 176.9 0.0 6.4e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Met_synt_B12 PF02965.17 KEZ36466.1 - 0.0019 17.7 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain HAD_2 PF13419.6 KEZ36467.1 - 4.3e-20 72.5 0.0 5.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ36467.1 - 1.4e-15 58.2 0.2 1.9e-14 54.5 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ36467.1 - 5.8e-08 33.4 0.0 8.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ36467.1 - 0.00012 22.0 0.0 0.00047 20.2 0.0 2.1 1 0 0 1 1 1 1 HAD-hyrolase-like FtsX PF02687.21 KEZ36468.1 - 9.9e-23 80.4 19.3 2.3e-15 56.8 7.9 5.3 5 1 1 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 KEZ36468.1 - 5.4e-21 75.8 15.9 4.5e-12 46.7 2.8 3.9 4 0 0 4 4 4 2 MacB-like periplasmic core domain 60KD_IMP PF02096.20 KEZ36468.1 - 0.26 11.2 3.6 0.44 10.4 0.2 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein DUF3561 PF12084.8 KEZ36468.1 - 0.68 10.0 7.8 2.7 8.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3561) ABC_tran PF00005.27 KEZ36469.1 - 2.8e-30 105.6 0.0 4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ36469.1 - 2.2e-05 24.0 0.0 0.044 13.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ36469.1 - 0.00016 21.3 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ36469.1 - 0.002 18.7 0.0 0.0031 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEZ36469.1 - 0.0021 18.0 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KEZ36469.1 - 0.0026 17.6 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ36469.1 - 0.003 18.0 0.1 0.0078 16.6 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KEZ36469.1 - 0.0032 17.1 0.1 0.0079 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ36469.1 - 0.0069 16.7 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ36469.1 - 0.044 13.5 0.1 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEZ36469.1 - 0.083 12.6 0.0 0.95 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KEZ36469.1 - 0.13 11.6 0.1 0.68 9.2 0.0 1.9 2 0 0 2 2 2 0 KaiC RecA PF00154.21 KEZ36469.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PDDEXK_1 PF12705.7 KEZ36470.1 - 1.6e-37 129.8 0.0 1.9e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 KEZ36470.1 - 2e-06 27.4 0.0 4.5e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2800) Cas_Cas4 PF01930.17 KEZ36470.1 - 0.00043 20.4 0.0 0.0012 18.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF83 Dna2 PF08696.11 KEZ36470.1 - 0.059 13.2 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 Peptidase_M50 PF02163.22 KEZ36471.1 - 1.4e-07 31.1 11.5 2.1e-05 23.9 0.2 3.1 2 1 0 2 2 2 2 Peptidase family M50 Peptidase_M50B PF13398.6 KEZ36471.1 - 0.0025 17.5 5.3 0.0025 17.5 5.3 2.1 1 1 1 2 2 2 1 Peptidase M50B-like CoA_binding_3 PF13727.6 KEZ36471.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 CoA-binding domain GCD14_N PF14801.6 KEZ36472.1 - 4.7e-27 93.6 1.7 8.2e-27 92.8 1.7 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 KEZ36472.1 - 3.5e-20 72.7 0.0 1.2e-18 67.7 0.0 2.3 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KEZ36472.1 - 5.2e-09 36.2 0.0 8.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KEZ36472.1 - 0.0017 17.5 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KEZ36472.1 - 0.015 16.0 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KEZ36472.1 - 0.036 15.1 0.1 0.07 14.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fer4_15 PF13459.6 KEZ36473.1 - 5.1e-19 68.8 1.0 6e-19 68.5 1.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KEZ36473.1 - 9.5e-12 45.3 0.4 1.3e-11 44.8 0.4 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 KEZ36473.1 - 0.0029 17.7 0.1 0.0059 16.7 0.1 1.7 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 KEZ36473.1 - 0.028 14.2 2.6 0.03 14.2 0.1 2.1 2 1 0 2 2 2 0 4Fe-4S binding domain AAA PF00004.29 KEZ36474.1 - 2.2e-47 160.8 0.0 9e-47 158.8 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 KEZ36474.1 - 3.2e-24 84.3 0.3 7.9e-24 83.1 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain Prot_ATP_ID_OB PF16450.5 KEZ36474.1 - 4.6e-16 58.5 0.3 3.8e-14 52.4 0.0 2.8 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KEZ36474.1 - 2.5e-07 31.2 1.5 7.8e-06 26.4 0.1 2.8 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 KEZ36474.1 - 3.9e-05 23.5 0.0 0.00098 18.9 0.0 2.8 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ36474.1 - 6.4e-05 23.2 0.3 0.00029 21.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KEZ36474.1 - 7.8e-05 22.7 0.0 0.00022 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KEZ36474.1 - 9.1e-05 23.1 0.2 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATG16 PF08614.11 KEZ36474.1 - 0.00018 21.8 2.4 0.00034 20.9 2.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) RNA_helicase PF00910.22 KEZ36474.1 - 0.00048 20.5 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 KEZ36474.1 - 0.00055 20.1 0.0 0.0029 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Cep57_CLD_2 PF14197.6 KEZ36474.1 - 0.00081 19.4 6.6 0.0068 16.5 6.3 2.4 1 1 0 1 1 1 1 Centrosome localisation domain of PPC89 SOGA PF11365.8 KEZ36474.1 - 0.0013 19.8 3.4 0.0051 17.9 3.4 2.0 1 1 0 1 1 1 1 Protein SOGA ATPase_2 PF01637.18 KEZ36474.1 - 0.0013 18.7 0.0 0.15 12.0 0.0 2.7 1 1 0 2 2 2 1 ATPase domain predominantly from Archaea CALCOCO1 PF07888.11 KEZ36474.1 - 0.0018 17.2 2.1 0.0029 16.6 2.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Mg_chelatase PF01078.21 KEZ36474.1 - 0.003 17.0 0.1 0.0072 15.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KEZ36474.1 - 0.0048 16.1 0.0 0.0099 15.1 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain Jnk-SapK_ap_N PF09744.9 KEZ36474.1 - 0.007 16.6 3.5 0.016 15.4 3.5 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ABC_tran_CTD PF16326.5 KEZ36474.1 - 0.0085 16.3 1.0 0.0085 16.3 1.0 2.3 2 1 1 3 3 2 1 ABC transporter C-terminal domain FAM76 PF16046.5 KEZ36474.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 FAM76 protein BicD PF09730.9 KEZ36474.1 - 0.013 14.0 3.4 0.019 13.4 3.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Zeta_toxin PF06414.12 KEZ36474.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KEZ36474.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KEZ36474.1 - 0.015 15.2 0.1 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Spc7 PF08317.11 KEZ36474.1 - 0.023 13.6 0.2 0.035 13.0 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IstB_IS21 PF01695.17 KEZ36474.1 - 0.023 14.4 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KEZ36474.1 - 0.023 14.3 0.4 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2968 PF11180.8 KEZ36474.1 - 0.025 14.2 2.7 0.043 13.5 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Tektin PF03148.14 KEZ36474.1 - 0.038 12.7 1.7 0.077 11.7 1.7 1.5 1 0 0 1 1 1 0 Tektin family AAA_18 PF13238.6 KEZ36474.1 - 0.056 14.0 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ36474.1 - 0.065 13.1 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 NACHT domain CENP-F_leu_zip PF10473.9 KEZ36474.1 - 0.069 13.2 3.1 0.22 11.6 3.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KEZ36474.1 - 0.07 12.8 5.5 0.15 11.7 5.5 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Zot PF05707.12 KEZ36474.1 - 0.074 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PhoH PF02562.16 KEZ36474.1 - 0.076 12.4 0.1 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TolA_bind_tri PF16331.5 KEZ36474.1 - 0.08 13.0 4.6 0.062 13.4 2.2 2.1 2 0 0 2 2 1 0 TolA binding protein trimerisation FapA PF03961.13 KEZ36474.1 - 0.082 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ABC_tran PF00005.27 KEZ36474.1 - 0.096 13.2 0.2 0.43 11.1 0.0 2.2 2 0 0 2 2 1 0 ABC transporter APG6_N PF17675.1 KEZ36474.1 - 0.099 13.2 5.6 0.2 12.2 5.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Parvo_NS1 PF01057.17 KEZ36474.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KEZ36474.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TMF_DNA_bd PF12329.8 KEZ36474.1 - 0.13 12.3 2.6 0.47 10.5 0.5 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 KEZ36474.1 - 0.13 11.9 1.9 0.27 10.9 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_24 PF13479.6 KEZ36474.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEZ36474.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KEZ36474.1 - 0.15 12.1 0.0 1.5 9.0 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain FlaC_arch PF05377.11 KEZ36474.1 - 0.17 12.3 4.5 26 5.3 0.3 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.19 KEZ36474.1 - 0.19 9.5 6.1 0.27 9.0 6.1 1.1 1 0 0 1 1 1 0 Myosin tail Fez1 PF06818.15 KEZ36474.1 - 0.19 12.1 1.4 0.36 11.3 0.4 1.9 2 0 0 2 2 1 0 Fez1 Lzipper-MIP1 PF14389.6 KEZ36474.1 - 0.2 11.9 3.6 0.24 11.7 0.4 2.3 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.6 KEZ36474.1 - 0.23 10.8 4.6 0.82 9.0 4.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 KEZ36474.1 - 0.24 9.9 0.5 0.33 9.4 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 KEZ36474.1 - 0.26 11.1 4.5 0.77 9.5 4.5 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KEZ36474.1 - 0.33 11.1 4.2 6.9 6.8 0.9 2.8 2 1 1 3 3 2 0 bZIP transcription factor Cnn_1N PF07989.11 KEZ36474.1 - 0.35 11.1 3.9 37 4.6 4.0 2.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 KEZ36474.1 - 0.51 10.4 4.1 1.1 9.3 4.1 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 KEZ36474.1 - 0.87 8.7 5.7 1.5 8.0 5.7 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ZapB PF06005.12 KEZ36474.1 - 0.93 10.0 8.9 0.88 10.1 3.5 3.0 2 1 1 3 3 3 0 Cell division protein ZapB Uso1_p115_C PF04871.13 KEZ36474.1 - 1.2 9.6 3.8 5.9 7.3 3.8 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 KEZ36474.1 - 1.5 9.1 5.8 14 6.0 5.7 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FPP PF05911.11 KEZ36474.1 - 2.7 6.1 5.3 3.3 5.8 1.8 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil SlyX PF04102.12 KEZ36474.1 - 5.7 7.6 10.2 1.9 9.2 2.5 3.3 2 1 1 3 3 2 0 SlyX DUF1192 PF06698.11 KEZ36474.1 - 6.3 6.9 6.9 6.8 6.8 0.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Pup_ligase PF03136.15 KEZ36475.1 - 1.1e-183 611.3 0.0 1.2e-183 611.1 0.0 1.0 1 0 0 1 1 1 1 Pup-ligase protein Pup PF05639.11 KEZ36476.1 - 1.3e-30 106.1 7.1 1.5e-30 105.9 7.1 1.0 1 0 0 1 1 1 1 Pup-like protein Apolipoprotein PF01442.18 KEZ36476.1 - 0.0095 15.8 0.8 0.011 15.6 0.8 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Tnp_P_element_C PF12596.8 KEZ36476.1 - 0.018 15.6 0.7 0.022 15.3 0.7 1.1 1 0 0 1 1 1 0 87kDa Transposase TH1 PF04858.13 KEZ36476.1 - 0.026 13.2 0.7 0.028 13.1 0.7 1.0 1 0 0 1 1 1 0 TH1 protein Snapin_Pallidin PF14712.6 KEZ36476.1 - 0.028 14.9 0.4 0.044 14.2 0.3 1.3 1 1 0 1 1 1 0 Snapin/Pallidin DFF40 PF09230.10 KEZ36476.1 - 0.058 13.0 0.1 0.061 12.9 0.1 1.0 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Zw10 PF06248.13 KEZ36476.1 - 0.088 11.4 0.3 0.087 11.4 0.3 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 HalX PF08663.10 KEZ36476.1 - 4.3 7.7 10.8 0.79 10.1 4.3 2.0 1 1 1 2 2 2 0 HalX domain Proteasome PF00227.26 KEZ36477.1 - 2e-36 125.3 0.4 2.7e-36 124.8 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KEZ36478.1 - 1.2e-29 103.2 0.2 1.6e-29 102.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit adh_short_C2 PF13561.6 KEZ36480.1 - 5.6e-34 117.7 2.8 6.8e-34 117.4 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ36480.1 - 6.8e-24 84.4 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ36480.1 - 1.4e-06 28.3 0.5 2.2e-06 27.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ36480.1 - 0.0043 16.6 0.2 0.0043 16.6 0.2 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KEZ36480.1 - 0.0073 16.0 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KEZ36480.1 - 0.039 13.3 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KEZ36480.1 - 0.059 13.4 0.4 0.16 12.0 0.4 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TetR_C_11 PF16859.5 KEZ36481.1 - 4.7e-30 104.2 3.6 7e-30 103.7 3.6 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ36481.1 - 3.7e-13 49.0 0.1 6.9e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 KEZ36481.1 - 2e-05 24.6 0.3 3.1e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_6 PF13977.6 KEZ36481.1 - 0.00077 19.7 1.9 0.0015 18.7 1.9 1.5 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal BTAD PF03704.17 KEZ36481.1 - 0.0099 16.3 0.4 0.51 10.8 0.1 2.7 3 0 0 3 3 3 1 Bacterial transcriptional activator domain HTH_7 PF02796.15 KEZ36481.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TetR_C_16 PF17920.1 KEZ36481.1 - 0.014 15.6 2.1 0.054 13.7 2.1 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 KEZ36481.1 - 0.023 15.1 2.1 0.26 11.8 2.1 2.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Glyco_trans_2_3 PF13632.6 KEZ36481.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 HTH_18 PF12833.7 KEZ36482.1 - 2.9e-14 53.1 0.5 2.9e-14 53.1 0.5 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 KEZ36482.1 - 4.5e-08 33.0 0.0 2.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Glyoxalase PF00903.25 KEZ36482.1 - 0.0039 17.4 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEZ36482.1 - 0.0045 17.8 0.1 0.0052 17.6 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain ABC_tran PF00005.27 KEZ36483.1 - 1.9e-19 70.6 0.0 2.7e-10 40.9 0.0 4.4 3 1 0 3 3 3 3 ABC transporter AAA_16 PF13191.6 KEZ36483.1 - 2.5e-08 34.5 2.6 0.036 14.4 0.1 4.1 5 0 0 5 5 4 2 AAA ATPase domain SMC_N PF02463.19 KEZ36483.1 - 3.1e-08 33.3 0.0 0.049 13.1 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ36483.1 - 1.3e-06 28.0 0.2 0.017 14.8 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEZ36483.1 - 2.9e-06 27.3 12.2 0.00094 19.1 0.1 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DnaJ_CXXCXGXG PF00684.19 KEZ36483.1 - 4e-06 27.1 7.4 0.0012 19.1 0.5 3.3 3 0 0 3 3 3 2 DnaJ central domain RsgA_GTPase PF03193.16 KEZ36483.1 - 0.00019 21.4 0.2 0.026 14.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 KEZ36483.1 - 0.00023 21.0 0.0 4.8 6.8 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain Anti-TRAP PF15777.5 KEZ36483.1 - 0.00093 19.1 8.1 0.96 9.5 0.1 3.8 3 1 1 4 4 4 3 Tryptophan RNA-binding attenuator protein inhibitory protein NACHT PF05729.12 KEZ36483.1 - 0.0083 16.1 0.2 1.4 8.8 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KEZ36483.1 - 0.019 15.1 4.0 2.5 8.2 0.1 3.2 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 KEZ36483.1 - 0.026 15.0 0.0 0.56 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrA_DNA-bind PF17755.1 KEZ36483.1 - 0.042 14.2 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 UvrA DNA-binding domain AAA_25 PF13481.6 KEZ36483.1 - 0.075 12.6 0.4 21 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KEZ36483.1 - 0.18 12.3 5.2 21 5.7 0.9 3.5 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KEZ36483.1 - 0.19 10.9 1.5 4.2 6.5 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KEZ36483.1 - 0.36 10.5 5.8 1.4 8.6 0.9 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KEZ36483.1 - 0.4 10.3 5.7 6.8 6.2 0.2 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 KEZ36483.1 - 0.49 9.5 2.3 7.1 5.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) zinc_ribbon_9 PF14369.6 KEZ36483.1 - 0.56 10.5 5.6 22 5.4 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon AAA_22 PF13401.6 KEZ36483.1 - 0.7 10.2 8.1 27 5.0 0.0 4.1 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 KEZ36483.1 - 0.99 8.7 2.2 29 3.9 0.0 2.7 3 0 0 3 3 3 0 KaiC zf-TFIIB PF13453.6 KEZ36483.1 - 1.9 7.9 7.4 14 5.1 0.0 3.6 3 1 0 3 3 3 0 Transcription factor zinc-finger AAA_30 PF13604.6 KEZ36483.1 - 2.1 8.0 9.2 6.3 6.5 0.4 3.9 4 0 0 4 4 4 0 AAA domain DUF5351 PF17302.2 KEZ36483.1 - 4.3 7.6 11.3 0.49 10.6 0.5 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5351) DUF234 PF03008.14 KEZ36484.1 - 4e-13 49.7 0.0 8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Archaea bacterial proteins of unknown function ATPase_2 PF01637.18 KEZ36484.1 - 6.6e-13 49.1 0.0 2.4e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KEZ36484.1 - 3e-06 27.7 0.4 1.1e-05 25.9 0.4 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KEZ36484.1 - 2.7e-05 24.2 0.0 7.6e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ36484.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KEZ36484.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein KNOX2 PF03791.13 KEZ36484.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 KNOX2 domain AsiA PF09010.10 KEZ36485.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 Anti-Sigma Factor A PIN PF01850.21 KEZ36486.1 - 1.2e-07 32.3 0.0 1.4e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 PIN domain Transposase_mut PF00872.18 KEZ36489.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Transposase, Mutator family Calci_bind_CcbP PF11535.8 KEZ36491.1 - 0.0048 17.4 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 Calcium binding E1-E2_ATPase PF00122.20 KEZ36492.1 - 1.4e-12 47.5 0.8 1.8e-12 47.2 0.8 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DLH PF01738.18 KEZ36493.1 - 1.2e-39 136.1 0.0 1.5e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KEZ36493.1 - 7e-07 29.3 0.0 9.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KEZ36493.1 - 2e-05 24.0 0.1 0.03 13.6 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KEZ36493.1 - 0.00029 20.8 0.1 0.73 9.7 0.0 3.0 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KEZ36493.1 - 0.0011 18.7 0.1 0.0048 16.6 0.1 1.8 1 1 1 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KEZ36493.1 - 0.011 15.3 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ36493.1 - 0.051 13.4 1.1 1.4 8.7 0.0 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KEZ36493.1 - 0.053 13.2 0.1 2.1 7.9 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold ABC2_membrane_3 PF12698.7 KEZ36494.1 - 0.22 10.6 3.5 0.39 9.8 0.0 2.3 2 1 1 3 3 3 0 ABC-2 family transporter protein Pup_ligase PF03136.15 KEZ36495.1 - 2.1e-157 524.7 0.1 4.2e-157 523.7 0.1 1.4 1 1 0 1 1 1 1 Pup-ligase protein FKBP_C PF00254.28 KEZ36496.1 - 7.9e-23 80.6 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WYL PF13280.6 KEZ36497.1 - 8.9e-29 100.7 0.0 1.5e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 WYL domain WYL PF13280.6 KEZ36498.1 - 2.3e-38 132.0 0.4 4.6e-38 131.0 0.5 1.5 2 0 0 2 2 2 1 WYL domain HTH_28 PF13518.6 KEZ36498.1 - 0.0012 19.0 1.8 0.041 14.0 0.0 3.1 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ36498.1 - 0.013 15.3 0.3 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF3318 PF11780.8 KEZ36499.1 - 0.0038 17.2 1.0 0.0044 17.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) DUF4164 PF13747.6 KEZ36499.1 - 0.0083 16.4 0.5 0.0093 16.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) LapA_dom PF06305.11 KEZ36499.1 - 0.027 14.3 4.7 0.04 13.7 4.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MttA_Hcf106 PF02416.16 KEZ36500.1 - 2.1e-19 68.6 0.0 2.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 KEZ36501.1 - 9.2e-61 205.3 8.7 1.1e-60 205.0 8.7 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF4956 PF16316.5 KEZ36501.1 - 0.11 12.2 1.7 4.9 6.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) DUF2530 PF10745.9 KEZ36501.1 - 1 9.6 0.0 1 9.6 0.0 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF2530) DUF3275 PF11679.8 KEZ36501.1 - 2.4 8.1 3.8 3.5 7.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DSHCT PF08148.12 KEZ36502.1 - 5.4e-42 143.2 0.0 1e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KEZ36502.1 - 1.7e-19 70.3 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEZ36502.1 - 2.3e-07 31.0 0.0 3.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 KEZ36502.1 - 1.9e-05 24.8 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 KEZ36502.1 - 3.8e-05 24.0 0.0 8.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.17 KEZ36502.1 - 0.0012 18.6 0.6 0.73 9.5 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_30 PF13604.6 KEZ36502.1 - 0.04 13.6 0.3 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEZ36502.1 - 4.3 7.7 8.0 1.4 9.3 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain CobD_Cbib PF03186.13 KEZ36503.1 - 3.5e-85 285.6 5.5 5e-85 285.1 5.5 1.2 1 0 0 1 1 1 1 CobD/Cbib protein GATase_3 PF07685.14 KEZ36504.1 - 8.1e-43 146.3 0.0 1.1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 KEZ36504.1 - 2.6e-21 76.0 0.0 4.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KEZ36504.1 - 1.4e-15 57.6 0.0 8.6e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain SNO PF01174.19 KEZ36504.1 - 0.00028 20.8 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.28 KEZ36504.1 - 0.0057 16.4 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KEZ36504.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Trypan_PARP PF05887.11 KEZ36504.1 - 0.045 13.7 2.8 0.097 12.6 2.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABC_tran PF00005.27 KEZ36505.1 - 5.5e-25 88.5 0.0 7.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF4162 PF13732.6 KEZ36505.1 - 4.1e-07 30.6 0.0 7.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_21 PF13304.6 KEZ36505.1 - 8.4e-06 25.8 0.0 0.083 12.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ36505.1 - 0.024 14.4 0.3 0.069 12.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain MukB PF04310.12 KEZ36505.1 - 0.036 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal SbcCD_C PF13558.6 KEZ36505.1 - 0.087 13.1 0.1 0.28 11.4 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KEZ36505.1 - 0.087 13.3 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEZ36505.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KEZ36506.1 - 3e-33 115.4 4.5 4.4e-33 114.8 4.5 1.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEZ36506.1 - 1.2e-06 28.1 9.0 1.2e-06 28.1 9.0 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 KEZ36506.1 - 4.4e-06 26.3 4.5 4.4e-06 26.3 4.5 2.8 2 1 0 3 3 3 1 ABC-2 type transporter DUF5336 PF17270.2 KEZ36506.1 - 0.42 10.2 16.7 0.41 10.2 15.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5336) Pribosyltran_N PF13793.6 KEZ36507.1 - 9.3e-39 132.0 0.0 3.4e-36 123.7 0.0 2.6 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEZ36507.1 - 2.6e-20 73.2 1.3 1.4e-19 70.8 0.1 2.3 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEZ36507.1 - 1.2e-10 41.2 0.8 1.4e-09 37.6 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ36507.1 - 4.4e-05 23.0 0.2 0.0028 17.1 0.1 2.2 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase NIT PF08376.10 KEZ36507.1 - 0.0012 19.4 0.5 0.0015 19.0 0.5 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing PRTase_2 PF15609.6 KEZ36507.1 - 0.018 14.6 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase HTH_5 PF01022.20 KEZ36508.1 - 1.5e-12 47.2 0.0 2.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KEZ36508.1 - 2.3e-10 40.4 0.5 4e-10 39.6 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ36508.1 - 5.2e-06 26.3 0.4 8.5e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 KEZ36508.1 - 0.00033 20.5 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KEZ36508.1 - 0.046 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RP-C PF03428.13 KEZ36508.1 - 0.085 12.5 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain Cation_efflux PF01545.21 KEZ36509.1 - 1.1e-31 110.1 16.4 1.4e-31 109.8 16.4 1.1 1 0 0 1 1 1 1 Cation efflux family KRTAP PF11759.8 KEZ36509.1 - 2.6 8.7 7.0 5.5 7.6 7.0 1.5 1 0 0 1 1 1 0 Keratin-associated matrix Acyl-CoA_dh_1 PF00441.24 KEZ36510.1 - 7.6e-43 146.3 2.6 1.2e-42 145.7 2.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ36510.1 - 4.9e-27 94.8 0.0 1.3e-26 93.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ36510.1 - 1.1e-24 86.5 0.1 2e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ36510.1 - 2.6e-12 47.2 2.0 4.2e-12 46.5 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 KEZ36511.1 - 1e-13 51.2 0.2 1.1e-13 51.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ36511.1 - 5.6e-07 29.4 0.4 7e-07 29.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 KEZ36511.1 - 8.3e-06 25.4 1.9 1.7e-05 24.4 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KEZ36512.1 - 1.7e-20 73.5 0.0 3.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ36512.1 - 1.2e-05 26.0 0.0 2.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Lar_restr_allev PF14354.6 KEZ36512.1 - 0.011 16.1 0.2 0.022 15.1 0.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Methyltransf_2 PF00891.18 KEZ36512.1 - 0.028 13.7 0.0 0.065 12.5 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain DNAPolymera_Pol PF11590.8 KEZ36512.1 - 0.033 14.1 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol DUF35_N PF12172.8 KEZ36512.1 - 0.049 13.5 5.0 0.11 12.4 0.3 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 KEZ36512.1 - 0.089 12.9 3.9 3.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Zinc ribbon domain DUF3291 PF11695.8 KEZ36514.1 - 4.1e-49 165.9 0.1 4.7e-49 165.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) DHO_dh PF01180.21 KEZ36515.1 - 1.4e-40 139.4 0.0 1.7e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KEZ36515.1 - 0.00078 18.9 0.5 0.0014 18.1 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glycos_transf_1 PF00534.20 KEZ36516.1 - 1.5e-32 112.5 0.0 2.1e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ36516.1 - 3.1e-26 92.7 16.7 1.2e-25 90.9 9.2 2.4 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KEZ36516.1 - 1e-25 90.7 0.2 1.6e-25 90.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ36516.1 - 8.8e-19 68.1 4.7 1.9e-15 57.3 3.6 2.7 2 1 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ36516.1 - 6.8e-06 26.4 0.0 2.2e-05 24.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferases group 1 Pyr_redox PF00070.27 KEZ36516.1 - 9.9e-05 22.8 0.0 0.24 12.0 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_2 PF13477.6 KEZ36516.1 - 0.00028 21.0 0.0 0.031 14.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase 4-like Lsm_C PF14894.6 KEZ36516.1 - 0.015 15.1 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Lsm C-terminal Glyco_transf_5 PF08323.11 KEZ36516.1 - 0.035 13.8 0.0 1 9.0 0.0 2.7 2 1 0 2 2 2 0 Starch synthase catalytic domain Thioredoxin_15 PF18403.1 KEZ36516.1 - 0.061 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain ABC_tran PF00005.27 KEZ36517.1 - 6.2e-28 98.0 0.0 9.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter FHA PF00498.26 KEZ36517.1 - 9.1e-25 86.8 2.0 1.2e-13 51.2 0.6 2.4 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 KEZ36517.1 - 2.7e-24 85.3 0.3 7e-12 45.5 0.1 2.4 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain ABC2_membrane PF01061.24 KEZ36517.1 - 5.9e-16 58.5 6.3 1.1e-15 57.6 6.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ36517.1 - 1e-14 54.5 2.1 1.4e-14 54.0 2.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KEZ36517.1 - 3.6e-11 43.4 0.0 2.3e-06 27.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEZ36517.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KEZ36517.1 - 0.00038 20.9 0.0 0.00071 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KEZ36517.1 - 0.00057 19.4 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ36517.1 - 0.00065 19.4 0.1 0.0021 17.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEZ36517.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEZ36517.1 - 0.0082 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_23 PF13476.6 KEZ36517.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KEZ36517.1 - 0.015 15.5 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KEZ36517.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ36517.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KEZ36517.1 - 0.081 12.6 0.0 3.5 7.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain FHA_2 PF17913.1 KEZ36517.1 - 0.12 12.6 0.0 0.69 10.2 0.0 2.0 2 0 0 2 2 2 0 FHA domain ABC2_membrane_2 PF12679.7 KEZ36517.1 - 2.5 7.3 11.2 0.87 8.8 8.2 1.6 1 1 0 2 2 2 0 ABC-2 family transporter protein RibD_C PF01872.17 KEZ36519.1 - 4.1e-43 147.6 0.0 1.3e-42 145.9 0.0 1.7 1 1 0 1 1 1 1 RibD C-terminal domain DUF4653 PF15546.6 KEZ36519.1 - 0.051 13.2 1.4 0.072 12.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF3597 PF12200.8 KEZ36519.1 - 0.22 12.1 0.1 0.41 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Exo_endo_phos PF03372.23 KEZ36520.1 - 1.9e-22 79.9 3.1 2.5e-22 79.6 3.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HSP20 PF00011.21 KEZ36521.1 - 6.8e-17 61.5 0.0 8.6e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KEZ36521.1 - 6e-08 32.1 0.0 9.2e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 KEZ36521.1 - 0.066 13.6 0.0 0.094 13.1 0.0 1.2 1 0 0 1 1 1 0 PIH1 CS-like domain AMP-binding PF00501.28 KEZ36522.1 - 1.9e-58 198.0 0.0 2.5e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KEZ36522.1 - 4.7e-27 95.6 1.0 6.9e-22 78.7 0.8 2.3 2 0 0 2 2 2 2 Thioesterase domain AMP-binding_C PF13193.6 KEZ36522.1 - 2.2e-13 51.0 0.6 5e-13 49.8 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KEZ36522.1 - 1.7e-12 47.5 0.3 3.8e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KEZ36522.1 - 4.6e-05 24.1 6.3 4.6e-05 24.1 6.3 3.6 2 1 2 4 4 4 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ36522.1 - 0.0077 15.5 0.1 0.038 13.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF4230 PF14014.6 KEZ36523.1 - 2.6e-26 92.6 0.0 3.1e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4230) SpoIIE PF07228.12 KEZ36524.1 - 9.8e-39 133.3 0.2 6.4e-22 78.4 0.1 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CHASE3 PF05227.13 KEZ36524.1 - 7.4e-24 84.2 3.1 7.4e-24 84.2 3.1 1.8 2 0 0 2 2 2 1 CHASE3 domain HAMP PF00672.25 KEZ36524.1 - 1.2e-09 38.4 2.9 7.4e-09 35.9 0.2 2.7 2 0 0 2 2 2 1 HAMP domain TarH PF02203.15 KEZ36524.1 - 0.087 12.7 4.1 0.22 11.5 0.2 2.5 2 0 0 2 2 2 0 Tar ligand binding domain homologue ABC_tran PF00005.27 KEZ36525.1 - 1.9e-23 83.5 0.0 2.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ36525.1 - 9.1e-14 52.0 0.2 1.6e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 KEZ36525.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KEZ36525.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KEZ36525.1 - 0.24 11.9 0.0 0.36 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KEZ36526.1 - 2.2e-06 27.2 25.6 4.6e-06 26.1 25.4 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KEZ36526.1 - 1.8e-05 24.7 0.6 1.8e-05 24.7 0.6 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 KEZ36526.1 - 0.0098 15.0 10.0 0.026 13.7 10.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein Nucleoporin_FG2 PF15967.5 KEZ36526.1 - 6 5.3 15.1 8.3 4.8 15.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Acyl_transf_3 PF01757.22 KEZ36527.1 - 1.7e-28 99.7 29.7 2e-28 99.4 29.7 1.0 1 0 0 1 1 1 1 Acyltransferase family Aldo_ket_red PF00248.21 KEZ36528.1 - 1.4e-45 155.8 0.0 2.7e-43 148.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1778 PF08681.11 KEZ36529.1 - 2e-17 62.9 0.0 2.4e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) RHH_1 PF01402.21 KEZ36529.1 - 0.0038 17.1 3.0 0.004 17.0 1.6 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family Metal_resist PF13801.6 KEZ36529.1 - 0.03 14.5 3.4 0.36 11.0 3.4 2.0 1 1 0 1 1 1 0 Heavy-metal resistance Endonuc-FokI_C PF09254.11 KEZ36529.1 - 0.069 12.4 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Acetyltransf_7 PF13508.7 KEZ36530.1 - 2.4e-07 31.1 0.0 4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ36530.1 - 6.2e-07 29.7 0.0 8.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ36530.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ36530.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KEZ36530.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Polysacc_synt PF01943.17 KEZ36532.1 - 0.00028 20.4 2.0 0.00028 20.4 2.0 3.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein Glycos_transf_1 PF00534.20 KEZ36533.1 - 7e-27 94.0 0.0 6.4e-16 58.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ36533.1 - 3.2e-26 92.4 0.0 1.1e-25 90.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ36533.1 - 5.5e-13 49.7 8.5 5.5e-13 49.7 8.5 3.4 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ36533.1 - 7.6e-13 48.8 0.4 2e-12 47.4 0.4 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ36533.1 - 3.6e-09 36.9 0.0 1.3e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pro-rich_19 PF15455.6 KEZ36533.1 - 0.0078 15.4 0.1 0.048 12.8 0.0 2.1 2 0 0 2 2 2 1 Proline-rich 19 3-HAO PF06052.12 KEZ36533.1 - 0.048 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase RyR PF02026.16 KEZ36534.1 - 6.4e-12 45.5 0.1 8.5e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 RyR domain DUF3367 PF11847.8 KEZ36535.1 - 1.4e-237 789.9 33.0 2.3e-237 789.1 33.0 1.3 1 0 0 1 1 1 1 Alpha-(1->3)-arabinofuranosyltransferase F5_F8_type_C PF00754.25 KEZ36535.1 - 0.0026 17.9 0.0 0.0067 16.5 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain DUF3357 PF11837.8 KEZ36535.1 - 1.7 9.1 5.5 22 5.6 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Glycos_transf_2 PF00535.26 KEZ36536.1 - 3.8e-29 101.7 0.0 5.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ36536.1 - 1.5e-10 41.4 0.0 1.9e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEZ36536.1 - 0.0027 17.2 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KEZ36536.1 - 0.041 14.4 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 AvrPtoB_bdg PF16847.5 KEZ36537.1 - 0.053 14.0 0.4 0.12 12.9 0.4 1.6 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain LacAB_rpiB PF02502.18 KEZ36538.1 - 4e-42 143.5 0.0 4.5e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4597 PF15366.6 KEZ36539.1 - 0.33 10.7 6.2 0.86 9.4 6.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4597) TALPID3 PF15324.6 KEZ36539.1 - 2 6.0 4.2 1.8 6.1 4.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target AI-2E_transport PF01594.16 KEZ36540.1 - 2.1e-59 201.4 18.6 2.5e-59 201.0 18.6 1.0 1 0 0 1 1 1 1 AI-2E family transporter ERAP1_C PF11838.8 KEZ36541.1 - 1.4e-58 199.0 6.0 2.8e-58 197.9 6.0 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KEZ36541.1 - 5.5e-58 196.1 1.7 8e-58 195.6 1.7 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KEZ36541.1 - 1.1e-19 71.4 0.0 4.1e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SprT-like PF10263.9 KEZ36541.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 SprT-like family DUF5130 PF17174.4 KEZ36542.1 - 2.3e-13 50.5 0.3 2.7e-13 50.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) TPM_phosphatase PF04536.14 KEZ36542.1 - 2.9e-06 27.5 0.0 3.8e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 TPM domain Glyco_hydro_77 PF02446.17 KEZ36544.1 - 1.1e-110 370.7 0.0 1.4e-110 370.3 0.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase HATPase_c PF02518.26 KEZ36545.1 - 3.4e-20 72.6 0.0 9.3e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ36545.1 - 3.5e-11 43.0 2.9 3.5e-11 43.0 2.9 2.6 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ36545.1 - 4.7e-11 42.9 1.4 4.7e-11 42.9 1.4 2.9 3 0 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 KEZ36545.1 - 0.0097 15.9 1.0 0.028 14.4 0.4 2.2 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KEZ36545.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ36546.1 - 5.3e-33 113.5 0.0 7.8e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ36546.1 - 2.4e-26 91.6 0.1 9e-26 89.8 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 KEZ36546.1 - 0.0004 20.7 0.0 0.00054 20.3 0.0 1.2 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ OKR_DC_1_N PF03709.15 KEZ36546.1 - 0.057 13.7 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4754 PF15946.5 KEZ36546.1 - 0.26 11.6 1.5 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) MS_channel PF00924.18 KEZ36547.1 - 1.3e-40 139.2 0.0 1.7e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel HNH_5 PF14279.6 KEZ36548.1 - 1.3e-11 44.2 0.0 2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 KEZ36548.1 - 6.7e-10 39.0 0.2 1e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KEZ36548.1 - 9.8e-05 22.2 0.0 0.00023 21.0 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease SPDY PF03771.16 KEZ36548.1 - 0.041 13.8 0.7 0.11 12.5 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) DUF2867 PF11066.8 KEZ36549.1 - 1.9e-37 128.8 1.2 2.9e-37 128.2 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2867) NAD_binding_10 PF13460.6 KEZ36549.1 - 4.7e-19 69.0 0.3 8.2e-19 68.2 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ36549.1 - 1e-12 48.2 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ36549.1 - 1.6e-09 37.6 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ36549.1 - 2.3e-06 26.8 0.0 4.6e-06 25.8 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KEZ36549.1 - 0.0004 19.9 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KEZ36549.1 - 0.0004 19.9 0.0 0.00055 19.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KEZ36549.1 - 0.00045 20.5 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain RmlD_sub_bind PF04321.17 KEZ36549.1 - 0.0028 16.8 0.0 0.0073 15.4 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEZ36549.1 - 0.12 11.5 0.1 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 KEZ36549.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 KR domain K_channel_TID PF07941.11 KEZ36549.1 - 1.7 9.2 9.9 2.6 8.5 0.3 2.9 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain SpoIIE PF07228.12 KEZ36550.1 - 4.6e-40 137.6 0.9 4.6e-40 137.6 0.9 2.0 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 KEZ36550.1 - 8e-09 35.5 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_2 PF13185.6 KEZ36550.1 - 6.3e-08 33.0 0.4 4.7e-07 30.2 0.1 2.5 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KEZ36550.1 - 4.8e-06 27.2 0.0 1.2e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KEZ36550.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 GAF domain Alpha-amylase PF00128.24 KEZ36551.1 - 6.3e-70 236.4 0.0 1.2e-69 235.4 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_4 PF13439.6 KEZ36551.1 - 0.15 12.1 2.3 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DUF3459 PF11941.8 KEZ36551.1 - 0.16 12.3 10.4 0.65 10.4 4.6 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KEZ36551.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Bac_globin PF01152.21 KEZ36552.1 - 3.1e-34 117.7 0.0 3.5e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin ABC_tran PF00005.27 KEZ36553.1 - 6.1e-49 166.1 0.0 5.1e-26 91.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEZ36553.1 - 4.6e-18 66.1 8.4 4.9e-05 23.3 0.1 4.2 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KEZ36553.1 - 3.3e-13 49.5 2.3 1.4e-11 44.2 2.3 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KEZ36553.1 - 3e-07 30.1 1.2 0.34 10.3 0.1 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KEZ36553.1 - 1.6e-05 24.9 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEZ36553.1 - 1.9e-05 25.0 0.6 0.013 15.8 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ36553.1 - 0.00021 21.0 1.3 0.47 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ36553.1 - 0.00021 21.3 0.3 0.45 10.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 KEZ36553.1 - 0.00028 20.7 1.0 0.36 10.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KEZ36553.1 - 0.00035 20.8 0.1 0.78 10.0 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KEZ36553.1 - 0.0014 18.8 0.2 0.35 11.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KEZ36553.1 - 0.0018 18.1 0.2 0.72 9.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KEZ36553.1 - 0.002 18.6 10.8 0.06 13.8 0.7 2.8 4 0 0 4 4 2 2 AAA domain Dynamin_N PF00350.23 KEZ36553.1 - 0.0026 17.9 0.0 0.17 11.9 0.0 2.5 2 1 0 2 2 2 1 Dynamin family SKA2 PF16740.5 KEZ36553.1 - 0.0031 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 AAA_28 PF13521.6 KEZ36553.1 - 0.0038 17.5 0.4 1.8 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KEZ36553.1 - 0.0068 16.9 0.2 7.3 7.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KEZ36553.1 - 0.012 15.3 0.6 0.43 10.2 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KEZ36553.1 - 0.015 15.7 0.7 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KEZ36553.1 - 0.015 15.5 0.8 15 5.9 0.0 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KEZ36553.1 - 0.024 15.1 10.3 0.42 11.0 0.0 3.9 2 2 1 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 KEZ36553.1 - 0.025 14.3 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEZ36553.1 - 0.03 13.9 0.5 4.3 6.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 KEZ36553.1 - 0.043 12.7 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_27 PF13514.6 KEZ36553.1 - 0.063 12.9 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ36553.1 - 0.076 13.4 0.1 13 6.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KEZ36553.1 - 0.12 12.4 0.1 3.3 7.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.18 KEZ36553.1 - 0.15 11.6 0.2 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Rad17 PF03215.15 KEZ36553.1 - 0.16 11.9 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KEZ36553.1 - 0.17 11.8 2.2 5.7 6.8 0.3 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KEZ36553.1 - 0.18 11.5 0.2 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KEZ36553.1 - 0.3 10.3 2.2 1.3 8.2 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KEZ36553.1 - 0.45 10.1 3.0 6 6.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain DUF1254 PF06863.12 KEZ36554.1 - 1.1e-37 129.1 0.0 2.8e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 KEZ36554.1 - 1.9e-28 99.1 0.0 3.6e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) PMT_2 PF13231.6 KEZ36555.1 - 2.3e-07 31.2 16.6 2.3e-07 31.2 16.6 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2079 PF09852.9 KEZ36555.1 - 0.005 15.7 13.1 0.0083 15.0 13.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) PMT PF02366.18 KEZ36555.1 - 0.027 14.1 13.3 0.054 13.1 13.3 1.5 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase SSB PF00436.25 KEZ36556.1 - 1.2e-23 83.1 0.0 1.9e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 KEZ36556.1 - 0.00081 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Phage_integrase PF00589.22 KEZ36557.1 - 3.8e-22 78.9 0.1 1.1e-21 77.4 0.0 1.8 2 1 1 3 3 3 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ36557.1 - 6.1e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3730 PF12530.8 KEZ36557.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) FtsK_SpoIIIE PF01580.18 KEZ36559.1 - 8.5e-09 35.1 0.0 2.1e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ36559.1 - 0.048 14.0 0.0 0.087 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KEZ36559.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain HTH_31 PF13560.6 KEZ36562.1 - 5.6e-10 39.4 4.5 1.3e-09 38.2 4.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ36562.1 - 0.00026 21.0 0.2 0.00079 19.4 0.2 1.7 1 1 1 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 KEZ36562.1 - 0.0005 20.5 0.0 0.0009 19.6 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain MLD PF11647.8 KEZ36562.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Membrane Localization Domain HTH_24 PF13412.6 KEZ36562.1 - 0.27 10.8 1.0 8 6.1 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 KEZ36565.1 - 1.7e-08 34.6 0.0 8.2e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ36565.1 - 2.2e-07 30.8 0.0 7.5e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_r4 PF04545.16 KEZ36565.1 - 0.00019 20.9 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_37 PF13744.6 KEZ36565.1 - 0.0015 18.4 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ36565.1 - 0.023 14.5 0.3 0.08 12.8 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain YdaS_antitoxin PF15943.5 KEZ36565.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT NUDIX PF00293.28 KEZ36566.1 - 3.2e-20 72.5 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEZ36566.1 - 0.013 15.4 0.0 0.02 14.9 0.0 1.3 1 1 0 1 1 1 0 NUDIX domain GATase_3 PF07685.14 KEZ36566.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain HD PF01966.22 KEZ36567.1 - 1.1e-07 32.1 0.1 1.3e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KEZ36567.1 - 0.00049 19.6 0.1 0.0012 18.4 0.1 1.7 1 1 0 1 1 1 1 HDOD domain Mrr_cat PF04471.12 KEZ36569.1 - 1.5e-29 102.3 0.0 2.4e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Mrr_N PF14338.6 KEZ36569.1 - 2e-22 79.1 0.0 3.8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Mrr N-terminal domain DUF2034 PF10356.9 KEZ36569.1 - 4e-05 23.1 0.1 0.13 11.6 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat_2 PF13156.6 KEZ36569.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Acetyltransf_3 PF13302.7 KEZ36570.1 - 2.7e-26 92.9 0.2 3.4e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ36570.1 - 3.6e-05 24.0 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEZ36570.1 - 0.024 14.3 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_31 PF13560.6 KEZ36571.1 - 7.7e-05 23.0 2.7 7.7e-05 23.0 2.7 3.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ36571.1 - 0.00017 21.6 0.1 0.0012 18.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 KEZ36571.1 - 0.023 15.1 0.1 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TPR_10 PF13374.6 KEZ36571.1 - 0.91 9.5 5.4 28 4.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF397 PF04149.12 KEZ36572.1 - 3.2e-05 23.9 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF397) FixS PF03597.15 KEZ36572.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type PCMT PF01135.19 KEZ36573.1 - 2.2e-24 86.4 0.0 2.7e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEZ36573.1 - 4.1e-05 23.4 0.0 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEZ36573.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase GCD14 PF08704.10 KEZ36573.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KEZ36573.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KEZ36573.1 - 0.025 15.3 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KEZ36573.1 - 0.028 13.7 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KEZ36573.1 - 0.035 13.2 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ACP_syn_III_C PF08541.10 KEZ36573.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Fibrillarin PF01269.17 KEZ36573.1 - 0.067 12.3 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_12 PF08242.12 KEZ36573.1 - 0.11 13.3 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ36573.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KEZ36575.1 - 1.4e-40 139.3 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEZ36575.1 - 1.8e-06 27.8 0.0 2.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ36575.1 - 0.00022 21.8 0.0 0.00049 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ36575.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 KEZ36575.1 - 0.009 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltr_RsmB-F PF01189.17 KEZ36575.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Lant_dehydr_N PF04738.13 KEZ36577.1 - 4.1e-186 619.9 28.7 5.4e-186 619.5 28.7 1.1 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus Lant_dehydr_C PF14028.6 KEZ36577.1 - 1.8e-23 83.5 8.1 1.8e-23 83.5 8.1 2.6 2 1 0 2 2 2 1 Lantibiotic biosynthesis dehydratase C-term LANC_like PF05147.13 KEZ36578.1 - 2.1e-47 161.4 0.0 2.6e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Lant_dehydr_C PF14028.6 KEZ36579.1 - 1.3e-47 162.9 0.9 1.6e-47 162.5 0.9 1.1 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term HTH_28 PF13518.6 KEZ36579.1 - 0.095 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain APH PF01636.23 KEZ36580.1 - 0.00026 21.0 7.4 0.00054 20.0 7.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ36580.1 - 0.09 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP-synt_E PF05680.12 KEZ36581.1 - 0.22 11.9 15.6 3.8 7.9 0.5 2.4 2 0 0 2 2 2 0 ATP synthase E chain DUF937 PF06078.11 KEZ36581.1 - 0.31 11.6 2.2 0.43 11.2 0.0 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) DUF4041 PF13250.6 KEZ36582.1 - 4.3e-20 71.3 0.2 1.3e-19 69.8 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4041) T5orf172 PF10544.9 KEZ36582.1 - 7.2e-12 45.8 0.1 7e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KEZ36582.1 - 5.1e-11 43.1 1.9 1.2e-10 41.9 0.0 2.5 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 HAUS-augmin3 PF14932.6 KEZ36582.1 - 0.25 10.9 5.9 0.25 10.9 4.4 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1682 PF07946.14 KEZ36582.1 - 4.1 6.5 9.8 6.5 5.9 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) cIII PF08134.11 KEZ36583.1 - 0.14 12.0 1.4 0.37 10.6 1.4 1.6 1 0 0 1 1 1 0 cIII protein family S_4TM PF18159.1 KEZ36584.1 - 2e-82 276.8 0.0 2.2e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 SMODS-associating 4TM effector domain DUF3040 PF11239.8 KEZ36584.1 - 0.017 15.3 6.8 0.13 12.6 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) OPA3 PF07047.12 KEZ36584.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) SMODS PF18144.1 KEZ36585.1 - 7.3e-24 84.8 0.0 9.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 KEZ36585.1 - 1.5e-06 28.4 0.1 2.3e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEZ36585.1 - 0.12 12.5 0.2 0.27 11.3 0.1 1.7 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase bacHORMA_2 PF18173.1 KEZ36586.1 - 3.7e-19 69.2 0.0 3.9e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial HORMA domain 2 AAA PF00004.29 KEZ36588.1 - 7e-17 62.1 0.0 1.3e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ36588.1 - 2.7e-06 27.9 1.0 0.00077 19.9 0.1 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KEZ36588.1 - 1.4e-05 24.8 1.8 0.00011 21.9 1.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ36588.1 - 1.4e-05 25.3 0.2 0.0021 18.4 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ36588.1 - 0.0013 18.5 1.0 0.0028 17.4 0.1 2.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEZ36588.1 - 0.0043 16.5 0.1 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEZ36588.1 - 0.0045 17.1 1.6 0.0081 16.3 0.1 2.4 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KEZ36588.1 - 0.0055 17.0 0.3 0.022 15.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ36588.1 - 0.008 16.7 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEZ36588.1 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEZ36588.1 - 0.012 15.6 0.7 0.085 12.9 0.3 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KEZ36588.1 - 0.018 14.8 0.0 0.047 13.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KEZ36588.1 - 0.045 14.1 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEZ36588.1 - 0.054 13.4 0.2 0.28 11.1 0.1 2.3 3 0 0 3 3 3 0 NACHT domain AAA_11 PF13086.6 KEZ36588.1 - 0.054 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KEZ36588.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KEZ36588.1 - 0.064 13.7 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEZ36588.1 - 0.07 13.5 0.5 0.12 12.6 0.4 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEZ36588.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KEZ36588.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DDE_Tnp_IS66_C PF13817.6 KEZ36591.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 IS66 C-terminal element PASTA PF03793.19 KEZ36593.1 - 2.9e-46 155.2 8.7 1.7e-12 47.0 0.4 4.8 4 1 0 4 4 4 4 PASTA domain Pkinase PF00069.25 KEZ36593.1 - 5.6e-42 143.9 0.0 7.3e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36593.1 - 4.5e-30 104.8 0.0 6.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ36593.1 - 1.5e-08 34.9 3.8 0.00041 20.4 0.3 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ36593.1 - 0.00039 19.3 0.0 0.00057 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEZ36593.1 - 0.0053 16.1 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ36593.1 - 0.034 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KEZ36593.1 - 0.054 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ThiG PF05690.14 KEZ36594.1 - 1.3e-95 319.4 5.8 1.6e-95 319.2 5.8 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KEZ36594.1 - 0.0015 18.0 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 KEZ36594.1 - 0.027 13.6 0.6 0.052 12.7 0.6 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 KEZ36594.1 - 0.21 10.6 4.3 0.39 9.7 4.3 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase BATS PF06968.13 KEZ36595.1 - 8.4e-20 70.7 0.0 2.1e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KEZ36595.1 - 5.6e-10 39.8 0.0 9.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Pyr_redox_2 PF07992.14 KEZ36596.1 - 1.6e-43 149.0 1.1 2.1e-43 148.7 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KEZ36596.1 - 1.4e-16 60.8 0.1 1.3e-15 57.8 0.0 2.7 2 1 0 2 2 2 1 Reductase C-terminal Pyr_redox PF00070.27 KEZ36596.1 - 1.4e-13 51.2 2.0 4.3e-12 46.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KEZ36596.1 - 0.0039 16.6 0.1 0.0039 16.6 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEZ36596.1 - 0.012 15.5 1.0 0.012 15.5 1.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEZ36596.1 - 0.033 13.8 0.3 0.033 13.8 0.3 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 KEZ36596.1 - 0.046 14.2 0.2 0.084 13.4 0.2 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 KEZ36596.1 - 0.12 11.6 2.2 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KEZ36596.1 - 0.31 10.3 2.4 0.32 10.3 0.1 1.8 2 0 0 2 2 2 0 ThiF family NAD_binding_8 PF13450.6 KEZ36596.1 - 0.48 10.7 11.7 0.97 9.7 1.9 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ36596.1 - 2.8 6.9 10.4 2.1 7.3 2.5 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KEZ36596.1 - 4.1 6.4 17.4 1.9 7.5 5.9 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KEZ36596.1 - 4.3 7.8 5.1 0.71 10.3 0.5 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 KEZ36597.1 - 2.2e-13 51.1 0.0 4.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KEZ36597.1 - 0.003 18.2 0.0 0.006 17.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Rv2175c_C PF18367.1 KEZ36598.1 - 1.4e-26 92.4 0.0 2.5e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function HTH_17 PF12728.7 KEZ36598.1 - 0.00017 21.7 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ36598.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 ThiS PF02597.20 KEZ36599.1 - 5.5e-08 33.4 0.2 6.6e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 ThiS family TMP-TENI PF02581.17 KEZ36600.1 - 3.4e-38 130.8 0.0 4e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phage_holin_3_7 PF05449.11 KEZ36601.1 - 0.064 13.3 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 DUF1905 PF08922.11 KEZ36603.1 - 0.031 14.3 0.4 3.1 7.9 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1905) Lactamase_B PF00753.27 KEZ36604.1 - 2.7e-27 96.1 2.3 3.9e-27 95.5 2.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ36604.1 - 5.4e-06 26.1 0.1 9.7e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TerD PF02342.18 KEZ36605.1 - 1e-76 256.6 0.0 1.1e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 TerD domain ParE_toxin PF05016.15 KEZ36606.1 - 0.023 15.3 0.0 0.046 14.3 0.0 1.5 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE TrmO_C PF18389.1 KEZ36606.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 TrmO C-terminal domain CoA_binding_2 PF13380.6 KEZ36607.1 - 2.7e-35 121.4 0.2 3e-35 121.2 0.2 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KEZ36607.1 - 0.0013 19.3 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain PMT PF02366.18 KEZ36608.1 - 0.061 12.9 12.2 0.11 12.0 12.2 1.4 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 KEZ36608.1 - 1.6 8.9 22.2 0.12 12.6 15.6 2.3 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Glycos_transf_2 PF00535.26 KEZ36609.1 - 5.1e-25 88.2 0.0 7.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ36609.1 - 1.2e-08 35.1 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MMS22L_N PF14910.6 KEZ36609.1 - 0.95 7.8 2.3 1.3 7.3 2.3 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal PAP2 PF01569.21 KEZ36610.1 - 2.1e-18 66.4 1.5 3.7e-18 65.6 1.5 1.4 1 0 0 1 1 1 1 PAP2 superfamily DAGK_cat PF00781.24 KEZ36610.1 - 4e-17 62.0 1.5 6e-17 61.4 1.5 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAP2_3 PF14378.6 KEZ36610.1 - 2.5e-09 37.1 1.6 5e-09 36.1 1.6 1.6 1 0 0 1 1 1 1 PAP2 superfamily NAD_kinase PF01513.21 KEZ36610.1 - 0.00076 18.8 0.8 0.0012 18.1 0.8 1.3 1 0 0 1 1 1 1 ATP-NAD kinase PDH_E1_M PF17831.1 KEZ36612.1 - 8.7e-111 369.0 0.0 1.4e-110 368.3 0.0 1.2 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 KEZ36612.1 - 1.3e-10 40.8 0.0 5.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain UPF0047 PF01894.17 KEZ36613.1 - 1.4e-22 80.0 0.0 1.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF3052 PF11253.8 KEZ36614.1 - 5.2e-48 162.1 5.1 5.9e-48 161.9 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) DUF4234 PF14018.6 KEZ36615.1 - 8.3e-14 51.5 0.6 1.2e-13 50.9 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4234) SfLAP PF11139.8 KEZ36615.1 - 0.02 14.4 1.1 0.033 13.6 1.1 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein FA_desaturase PF00487.24 KEZ36615.1 - 0.048 13.5 1.1 0.069 13.0 1.0 1.3 1 1 0 1 1 1 0 Fatty acid desaturase EptA_B_N PF08019.12 KEZ36615.1 - 0.6 10.0 2.0 2.6 7.9 1.1 1.9 1 1 1 2 2 2 0 Phosphoethanolamine transferase EptA/EptB AhpC-TSA PF00578.21 KEZ36616.1 - 1.2e-38 131.8 0.0 1.4e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ36616.1 - 2.3e-24 85.8 0.0 2.5e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 KEZ36616.1 - 0.00073 19.5 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA_2 PF13911.6 KEZ36616.1 - 0.018 15.1 0.1 1.3 9.2 0.0 2.1 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme Acetyltransf_3 PF13302.7 KEZ36618.1 - 7.9e-27 94.6 0.5 9.6e-27 94.3 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ36618.1 - 0.00014 22.1 0.1 0.00018 21.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPR_12 PF13424.6 KEZ36619.1 - 0.00091 19.5 11.9 0.028 14.7 0.8 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ36619.1 - 0.028 14.3 6.8 9.3 6.3 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ36619.1 - 0.037 14.7 3.3 0.037 14.7 3.3 4.9 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF1771 PF08590.10 KEZ36619.1 - 0.27 11.7 0.1 0.27 11.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) DUF397 PF04149.12 KEZ36621.1 - 2.2e-08 34.0 0.0 2.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Radical_SAM PF04055.21 KEZ36622.1 - 1.2e-08 35.5 0.0 1.4e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KEZ36622.1 - 0.00087 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KEZ36622.1 - 0.0029 17.9 0.0 0.0038 17.5 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 KEZ36622.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acyl-CoA_dh_1 PF00441.24 KEZ36628.1 - 1.6e-33 116.0 3.6 1.6e-33 116.0 3.6 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ36628.1 - 1.8e-21 76.9 0.0 5.9e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ36628.1 - 1.4e-20 73.2 0.0 2.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ36628.1 - 3.8e-06 27.2 1.0 3.8e-06 27.2 1.0 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1974 PF09317.11 KEZ36628.1 - 8.3e-05 22.3 0.1 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) HpaB_N PF11794.8 KEZ36628.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MarR_2 PF12802.7 KEZ36629.1 - 1.1e-10 41.2 0.2 2.7e-10 40.0 0.2 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KEZ36629.1 - 6.2e-07 29.8 0.0 8.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 KEZ36629.1 - 2.4e-05 24.1 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 MarR family SgrR_N PF12793.7 KEZ36629.1 - 0.041 14.1 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term Abhydrolase_6 PF12697.7 KEZ36630.1 - 5.8e-15 56.5 6.7 7.2e-15 56.2 6.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ36630.1 - 1.2e-14 54.6 0.1 3.6e-09 36.6 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ36630.1 - 1.7e-05 24.2 0.0 0.16 11.2 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEZ36630.1 - 0.0079 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KEZ36630.1 - 0.14 10.9 0.4 0.31 9.7 0.1 1.7 3 0 0 3 3 3 0 Ndr family Dabb PF07876.12 KEZ36631.1 - 2.1e-15 57.1 0.0 6.7e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain Polyketide_cyc2 PF10604.9 KEZ36631.1 - 0.00051 20.3 0.1 0.00056 20.2 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MipZ PF09140.11 KEZ36631.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.6 KEZ36632.1 - 7e-21 75.3 0.2 7e-21 75.3 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain GerE PF00196.19 KEZ36632.1 - 3.6e-16 58.5 0.0 6.9e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 KEZ36632.1 - 1.8e-06 28.2 0.0 8.1e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain HTH_23 PF13384.6 KEZ36632.1 - 2.4e-05 24.0 0.4 0.00012 21.8 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 KEZ36632.1 - 0.00011 21.9 0.0 0.059 13.2 0.0 2.8 2 0 0 2 2 2 2 HTH DNA binding domain HTH_28 PF13518.6 KEZ36632.1 - 0.00066 19.8 0.6 0.0099 16.0 0.1 3.5 2 1 0 2 2 2 1 Helix-turn-helix domain DUF2791 PF10923.8 KEZ36632.1 - 0.0049 15.8 0.1 0.014 14.3 0.1 1.7 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 KEZ36632.1 - 0.015 15.2 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Sigma70_r4_2 PF08281.12 KEZ36632.1 - 0.037 13.7 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 RsgA_GTPase PF03193.16 KEZ36632.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase HrpB1_HrpK PF09613.10 KEZ36632.1 - 2.8 7.6 7.1 0.89 9.2 0.4 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Cytochrom_D1 PF02239.16 KEZ36633.1 - 2.7e-07 29.5 0.6 0.008 14.7 0.0 3.3 3 1 1 4 4 4 3 Cytochrome D1 heme domain Lactonase PF10282.9 KEZ36633.1 - 0.0039 16.5 0.0 1.4 8.0 0.0 3.1 3 1 0 3 3 3 2 Lactonase, 7-bladed beta-propeller MF_alpha_N PF05436.11 KEZ36633.1 - 0.23 11.4 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus HTH_6 PF01418.17 KEZ36634.1 - 9.1e-20 70.4 0.5 1.8e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 KEZ36634.1 - 1.9e-13 50.4 2.6 3.2e-13 49.7 2.6 1.4 1 0 0 1 1 1 1 SIS domain HTH_IclR PF09339.10 KEZ36634.1 - 0.0032 17.3 0.2 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain SIS_2 PF13580.6 KEZ36634.1 - 0.0052 16.8 2.8 0.0097 15.9 0.4 2.3 2 1 1 3 3 3 1 SIS domain LIP PF03583.14 KEZ36634.1 - 0.12 11.7 3.4 0.11 11.8 0.5 2.3 3 0 0 3 3 3 0 Secretory lipase Trns_repr_metal PF02583.17 KEZ36634.1 - 0.29 11.5 2.1 13 6.2 0.1 2.9 2 1 0 2 2 2 0 Metal-sensitive transcriptional repressor VIT1 PF01988.19 KEZ36635.1 - 8.7e-52 176.1 20.7 1e-51 175.9 20.7 1.0 1 0 0 1 1 1 1 VIT family FAM199X PF15814.5 KEZ36635.1 - 1.9 7.5 3.5 2.7 7.0 3.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Fer4 PF00037.27 KEZ36637.1 - 6.5e-08 32.1 16.1 2.1e-07 30.5 5.5 2.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KEZ36637.1 - 4.7e-07 29.8 5.6 3e-06 27.2 0.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ36637.1 - 2.9e-06 27.6 11.0 0.00054 20.4 1.7 2.1 1 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KEZ36637.1 - 8e-06 26.3 10.8 1.6e-05 25.4 10.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KEZ36637.1 - 2.8e-05 23.9 11.3 4.7e-05 23.2 3.7 2.7 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 KEZ36637.1 - 8.5e-05 23.4 8.2 0.0015 19.4 2.4 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KEZ36637.1 - 0.0001 22.4 9.9 0.00016 21.7 9.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ36637.1 - 0.00032 20.6 4.0 0.00032 20.6 4.0 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 KEZ36637.1 - 0.0004 20.4 9.5 0.00063 19.8 9.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEZ36637.1 - 0.0017 18.7 2.7 0.0017 18.7 2.7 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 KEZ36637.1 - 0.0077 16.7 13.7 0.03 14.9 3.0 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KEZ36637.1 - 0.015 16.2 7.7 0.015 16.2 7.7 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain DUF295 PF03478.18 KEZ36637.1 - 0.52 9.9 3.1 0.43 10.2 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Fer4_13 PF13370.6 KEZ36637.1 - 1.9 9.1 10.9 0.51 10.9 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KEZ36637.1 - 9.3 6.5 9.9 0.77 10.0 3.4 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Rrf2 PF02082.20 KEZ36638.1 - 5.6e-18 65.1 0.4 7.6e-18 64.7 0.4 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_27 PF13463.6 KEZ36638.1 - 7.6e-07 29.5 0.5 1.5e-06 28.6 0.5 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 KEZ36638.1 - 3.8e-05 23.5 2.1 0.00015 21.6 1.3 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 KEZ36638.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 KEZ36638.1 - 0.02 14.4 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KEZ36638.1 - 0.033 14.2 1.5 0.076 13.1 1.4 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 KEZ36638.1 - 0.042 13.6 1.3 0.094 12.5 1.3 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 KEZ36638.1 - 0.051 13.4 0.2 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 Homeodomain-like domain Methyltransf_3 PF01596.17 KEZ36639.1 - 3.9e-52 176.5 0.0 4.6e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KEZ36639.1 - 1.8e-17 64.3 0.0 3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ36639.1 - 0.0063 17.2 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ36639.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KEZ36639.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 KEZ36639.1 - 0.24 11.0 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit HATPase_c PF02518.26 KEZ36640.1 - 1e-13 51.7 0.0 2.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KEZ36640.1 - 6e-12 45.8 1.1 6e-12 45.8 1.1 2.5 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 KEZ36640.1 - 1.5e-11 44.1 1.4 3.8e-11 42.9 1.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KEZ36640.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ36641.1 - 6.7e-26 90.7 0.0 8.9e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ36641.1 - 2.5e-20 72.3 0.0 4.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF43 PF01861.16 KEZ36642.1 - 1.9e-28 99.3 0.0 2.9e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain HTH_9 PF08221.11 KEZ36642.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Histidinol_dh PF00815.20 KEZ36643.1 - 4.1e-153 510.2 8.6 4.7e-153 510.0 8.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Aminotran_1_2 PF00155.21 KEZ36644.1 - 2.5e-51 175.0 0.0 3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II IGPD PF00475.18 KEZ36645.1 - 2.8e-61 206.0 0.9 3.6e-61 205.7 0.9 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Peptidase_C62 PF12380.8 KEZ36645.1 - 0.059 12.5 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Gill-associated viral 3C-like peptidase GATase PF00117.28 KEZ36646.1 - 6.3e-13 48.9 0.0 7.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KEZ36646.1 - 0.094 12.6 0.0 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 SNO glutamine amidotransferase family His_biosynth PF00977.21 KEZ36647.1 - 8.5e-64 215.1 1.0 9.7e-64 215.0 1.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KEZ36647.1 - 8.4e-08 32.0 9.3 8.4e-06 25.4 0.9 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.17 KEZ36647.1 - 4.2e-06 26.1 0.2 0.021 13.9 0.0 2.1 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KEZ36647.1 - 0.22 10.5 4.3 0.61 9.0 0.4 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEZ36647.1 - 5.5 5.9 9.3 0.53 9.2 2.2 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 KEZ36648.1 - 4.7e-84 281.4 0.0 5.3e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 KEZ36648.1 - 2.9e-06 26.6 0.0 0.00025 20.3 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 KEZ36648.1 - 1e-05 25.0 4.5 0.079 12.2 0.1 3.0 2 2 1 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KEZ36648.1 - 3.7e-05 23.3 5.8 0.061 12.7 2.5 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase DHO_dh PF01180.21 KEZ36648.1 - 0.00011 21.6 0.1 0.045 12.9 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 KEZ36648.1 - 0.00049 19.6 0.1 0.09 12.2 0.0 2.1 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 KEZ36648.1 - 0.00057 19.0 2.5 0.39 9.7 0.5 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 KEZ36648.1 - 0.014 14.8 0.2 2.6 7.4 0.0 2.4 2 1 0 2 2 2 0 Thiamine monophosphate synthase FMN_dh PF01070.18 KEZ36648.1 - 0.69 8.9 5.9 0.56 9.2 0.1 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PRA-CH PF01502.18 KEZ36650.1 - 4.4e-33 112.9 0.2 5.9e-33 112.5 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Chorismate_bind PF00425.18 KEZ36651.1 - 3.8e-93 311.8 0.0 5.8e-93 311.2 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KEZ36651.1 - 2.8e-33 115.1 0.0 1.8e-32 112.5 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Trp_oprn_chp PF09534.10 KEZ36652.1 - 3.8e-43 147.4 24.1 4.6e-43 147.1 24.1 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 KEZ36652.1 - 4.7 6.8 9.4 1.1 8.9 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) IGPS PF00218.21 KEZ36654.1 - 1.3e-76 257.2 0.0 1.4e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 KEZ36654.1 - 7e-05 22.0 3.4 0.021 13.9 1.6 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.21 KEZ36654.1 - 0.018 14.5 0.2 4.4 6.7 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein PALP PF00291.25 KEZ36655.1 - 3.2e-50 171.2 7.7 3.9e-50 170.9 7.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Succ_CoA_lig PF13607.6 KEZ36655.1 - 0.066 13.0 0.2 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Trp_syntA PF00290.20 KEZ36656.1 - 4.4e-74 248.6 0.3 5.2e-74 248.4 0.3 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain KDGP_aldolase PF07071.11 KEZ36656.1 - 2.5e-05 24.2 2.0 0.034 13.9 0.1 2.2 2 0 0 2 2 2 2 KDGP aldolase His_biosynth PF00977.21 KEZ36656.1 - 0.0017 17.9 0.3 0.0039 16.7 0.3 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 KEZ36656.1 - 0.04 13.4 1.2 0.1 12.0 0.7 1.8 2 0 0 2 2 2 0 PcrB family LGT PF01790.18 KEZ36657.1 - 7.5e-61 205.4 12.8 9.1e-61 205.2 12.8 1.1 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase GATase_2 PF00310.21 KEZ36658.1 - 4.2e-178 592.4 0.0 5.3e-178 592.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KEZ36658.1 - 9.6e-151 502.1 0.0 4.4e-150 499.9 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KEZ36658.1 - 3.4e-112 374.5 0.0 4.8e-112 374.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 KEZ36658.1 - 1.4e-82 276.0 2.1 2.3e-82 275.2 2.1 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KEZ36659.1 - 3.4e-26 92.2 0.2 9e-26 90.8 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KEZ36659.1 - 4.5e-24 84.4 0.0 6.7e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KEZ36659.1 - 1.8e-10 40.9 0.6 5.5e-10 39.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ36659.1 - 1.9e-08 34.7 0.1 0.00014 22.3 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEZ36659.1 - 3e-08 33.4 0.5 3e-08 33.4 0.5 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KEZ36659.1 - 1.8e-07 30.7 0.0 0.0055 16.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ36659.1 - 3.3e-07 30.0 0.2 6e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ36659.1 - 3.2e-06 26.1 0.6 1.6e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KEZ36659.1 - 3e-05 23.3 1.0 3e-05 23.3 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ36659.1 - 4.8e-05 22.8 0.4 4.8e-05 22.8 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 KEZ36659.1 - 5.7e-05 21.7 0.0 0.00057 18.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 KEZ36659.1 - 0.00011 21.9 1.6 0.00011 21.9 1.6 2.9 2 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEZ36659.1 - 0.00015 22.1 1.3 0.04 14.4 0.1 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KEZ36659.1 - 0.0006 19.1 0.4 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family F420_oxidored PF03807.17 KEZ36659.1 - 0.00093 19.7 0.0 0.22 12.1 0.1 2.8 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KEZ36659.1 - 0.0014 18.0 0.1 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEZ36659.1 - 0.0025 16.9 0.5 0.0025 16.9 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A AdoHcyase_NAD PF00670.21 KEZ36659.1 - 0.0038 17.3 0.2 2.6 8.1 0.0 2.4 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KEZ36659.1 - 0.0051 16.7 0.1 0.0096 15.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ36659.1 - 0.0068 15.8 0.3 0.085 12.2 0.0 2.4 3 0 0 3 3 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KEZ36659.1 - 0.0097 15.1 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KEZ36659.1 - 0.028 13.5 0.9 0.056 12.5 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KEZ36659.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 KEZ36659.1 - 0.067 12.8 1.7 0.084 12.4 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KEZ36659.1 - 0.13 12.3 0.1 3.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KEZ36659.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DJ-1_PfpI PF01965.24 KEZ36659.1 - 0.3 10.9 2.0 5.8 6.7 0.1 3.0 1 1 2 3 3 3 0 DJ-1/PfpI family Fer4_9 PF13187.6 KEZ36659.1 - 0.43 10.8 3.3 0.54 10.5 0.4 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 KEZ36659.1 - 0.82 9.6 3.7 0.34 10.9 0.2 2.2 3 0 0 3 3 1 0 FAD-NAD(P)-binding YjeF_N PF03853.15 KEZ36659.1 - 3.8 7.4 6.3 2.7 7.8 0.2 2.7 1 1 0 2 2 2 0 YjeF-related protein N-terminus ADK PF00406.22 KEZ36660.1 - 1.5e-42 145.2 0.0 1.9e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEZ36660.1 - 1.3e-20 74.2 0.0 1.8e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ36660.1 - 3.9e-07 30.3 0.0 6.4e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ36660.1 - 1.9e-05 25.2 0.0 4.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KEZ36660.1 - 0.024 14.5 0.1 0.051 13.4 0.0 1.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Thymidylate_kin PF02223.17 KEZ36660.1 - 0.052 13.2 0.0 3.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Hydin_ADK PF17213.3 KEZ36660.1 - 0.099 12.9 0.9 0.52 10.6 0.2 2.0 1 1 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF4159 PF13709.6 KEZ36660.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) PI-PLC-C1 PF16670.5 KEZ36661.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.4 2 0 0 2 2 2 1 Phosphoinositide phospholipase C, Ca2+-dependent TerB PF05099.13 KEZ36662.1 - 4.4e-33 114.3 0.4 5.2e-33 114.0 0.4 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF533 PF04391.12 KEZ36662.1 - 6.5e-05 22.6 2.1 0.019 14.6 0.8 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF533) zf-HC2 PF13490.6 KEZ36662.1 - 0.13 12.6 0.1 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative zinc-finger TauE PF01925.19 KEZ36663.1 - 5e-37 127.8 41.7 6.5e-37 127.4 41.7 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Oxidored_q2 PF00420.24 KEZ36663.1 - 0.22 11.2 4.6 0.57 9.8 4.6 1.7 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L AbiEi_4 PF13338.6 KEZ36664.1 - 5.9e-06 26.3 1.0 1.4e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin AbiEi_1 PF09407.10 KEZ36664.1 - 0.0003 21.1 0.4 0.011 16.0 0.2 2.5 2 0 0 2 2 2 1 AbiEi antitoxin C-terminal domain MTES_1575 PF18741.1 KEZ36664.1 - 0.00032 20.8 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 KEZ36664.1 - 0.0014 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MM_CoA_mutase PF01642.22 KEZ36665.1 - 2.6e-119 399.1 0.0 3.9e-119 398.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase MM_CoA_mutase PF01642.22 KEZ36666.1 - 8.5e-228 757.0 0.1 1e-227 756.8 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KEZ36666.1 - 8.9e-14 51.6 0.8 2e-13 50.4 0.8 1.7 1 0 0 1 1 1 1 B12 binding domain Ca_hom_mod PF14798.6 KEZ36666.1 - 0.056 12.5 0.1 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator MeaB PF03308.16 KEZ36667.1 - 1e-107 359.1 3.3 1.3e-107 358.7 3.3 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KEZ36667.1 - 6.2e-06 25.9 0.5 2.9e-05 23.7 0.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KEZ36667.1 - 2.5e-05 23.9 0.1 5.5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KEZ36667.1 - 0.0003 20.6 0.3 0.00096 19.0 0.3 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KEZ36667.1 - 0.001 18.8 1.4 0.0027 17.4 1.4 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEZ36667.1 - 0.002 17.8 1.5 0.013 15.1 1.5 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KEZ36667.1 - 0.0021 18.1 0.8 0.011 15.8 0.8 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KEZ36667.1 - 0.0021 18.6 0.7 0.0043 17.6 0.7 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEZ36667.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ36667.1 - 0.0027 17.8 0.3 0.011 15.8 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KEZ36667.1 - 0.0028 17.6 0.3 0.0046 16.9 0.3 1.3 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.17 KEZ36667.1 - 0.0099 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase GTP_EFTU PF00009.27 KEZ36667.1 - 0.02 14.4 0.1 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ArsA_ATPase PF02374.15 KEZ36667.1 - 0.02 14.1 0.6 0.02 14.1 0.6 1.9 2 1 1 3 3 3 0 Anion-transporting ATPase KTI12 PF08433.10 KEZ36667.1 - 0.021 14.3 0.1 0.1 12.0 0.1 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 KEZ36667.1 - 0.022 14.1 0.6 2.4 7.5 0.2 2.0 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KEZ36667.1 - 0.025 15.1 0.2 0.038 14.5 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ36667.1 - 0.039 14.4 0.4 0.074 13.4 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ36667.1 - 0.051 13.5 0.0 1.4 8.8 0.0 2.5 3 0 0 3 3 2 0 RsgA GTPase ABC_tran PF00005.27 KEZ36667.1 - 0.085 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 ABC transporter Fer4_NifH PF00142.18 KEZ36667.1 - 0.094 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 KEZ36667.1 - 0.14 12.4 0.2 0.45 10.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain DUF463 PF04317.12 KEZ36667.1 - 0.16 10.8 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_31 PF13614.6 KEZ36667.1 - 2 8.3 4.1 1.1 9.2 0.4 2.0 2 0 0 2 2 2 0 AAA domain ParA PF10609.9 KEZ36667.1 - 2.2 7.6 5.0 0.24 10.8 0.6 1.5 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase HSP70 PF00012.20 KEZ36668.1 - 1.5e-29 102.7 0.0 2.4e-24 85.5 0.0 2.1 1 1 1 2 2 2 2 Hsp70 protein PBP_like PF12727.7 KEZ36668.1 - 3.6e-16 58.9 0.0 7.1e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 KEZ36668.1 - 2.6e-15 56.9 0.1 7.1e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 PBP superfamily domain MreB_Mbl PF06723.13 KEZ36668.1 - 0.054 12.3 0.0 0.37 9.6 0.0 2.3 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.25 KEZ36669.1 - 1.6e-38 132.6 0.0 2.2e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36669.1 - 8.3e-23 81.0 0.0 1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KEZ36669.1 - 1.2e-14 54.4 5.7 0.00079 20.2 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEZ36669.1 - 0.00023 20.2 0.0 2.4 7.0 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein APH PF01636.23 KEZ36669.1 - 0.00037 20.5 0.1 0.00037 20.5 0.1 3.1 3 1 1 4 4 4 2 Phosphotransferase enzyme family PD40 PF07676.12 KEZ36669.1 - 0.0017 18.2 0.1 0.17 11.9 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KEZ36669.1 - 0.0022 18.3 0.0 2 8.7 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_fungal PF17667.1 KEZ36669.1 - 0.0051 15.6 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 KEZ36669.1 - 0.076 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Nbas_N PF15492.6 KEZ36669.1 - 0.085 12.2 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RIO1 PF01163.22 KEZ36669.1 - 0.12 12.0 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KEZ36669.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pex14_N PF04695.13 KEZ36669.1 - 8.3 7.0 8.8 16 6.1 8.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_25 PF13649.6 KEZ36670.1 - 0.0011 19.6 0.0 0.0032 18.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEZ36670.1 - 0.0046 16.5 0.0 0.0086 15.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KEZ36670.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KEZ36670.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF21 PF01595.20 KEZ36671.1 - 1.1e-38 132.7 4.3 1.5e-38 132.2 4.3 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEZ36671.1 - 9.3e-11 42.0 0.8 0.00062 20.2 0.0 2.9 3 0 0 3 3 3 2 CBS domain DUF21 PF01595.20 KEZ36672.1 - 1.5e-32 112.7 2.8 2.2e-32 112.2 2.8 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 KEZ36672.1 - 2.4e-20 72.3 0.0 4.2e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 KEZ36672.1 - 3.5e-12 46.6 6.6 1.7e-06 28.4 0.5 2.9 3 0 0 3 3 3 2 CBS domain PetG PF02529.15 KEZ36672.1 - 0.18 11.6 4.1 0.52 10.2 4.1 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF4232 PF14016.6 KEZ36673.1 - 3.2e-31 108.1 5.5 5.1e-31 107.5 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) Thiolase_N PF00108.23 KEZ36674.1 - 1e-60 205.3 0.2 1.9e-60 204.5 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ36674.1 - 9.5e-41 138.3 0.0 2.2e-40 137.1 0.0 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEZ36674.1 - 0.042 13.4 1.1 0.1 12.2 0.6 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 KEZ36674.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Dodecin NMT1_3 PF16868.5 KEZ36675.1 - 1.6e-20 73.7 0.0 2.3e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 KEZ36675.1 - 0.093 12.1 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DDE_Tnp_IS66_C PF13817.6 KEZ36676.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 IS66 C-terminal element Response_reg PF00072.24 KEZ36677.1 - 7.1e-26 90.6 0.1 1e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ36677.1 - 8.1e-16 57.3 0.1 1.2e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ36677.1 - 2.3e-07 30.4 0.1 4e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ36677.1 - 5.5e-05 22.6 0.1 9.7e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KEZ36677.1 - 0.033 13.7 0.0 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KEZ36677.1 - 0.14 12.0 0.2 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain HATPase_c_2 PF13581.6 KEZ36678.1 - 0.0098 15.8 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA_3 PF07730.13 KEZ36679.1 - 7e-14 52.1 8.1 7e-14 52.1 8.1 2.0 1 1 1 2 2 2 1 Histidine kinase PaREP1 PF05942.11 KEZ36679.1 - 0.06 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family DUF2484 PF10658.9 KEZ36679.1 - 2.4 8.5 10.1 0.19 12.0 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2484) DUF4131 PF13567.6 KEZ36679.1 - 4.6 6.9 11.4 9.4 5.9 0.3 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Thymidylate_kin PF02223.17 KEZ36680.1 - 3.4e-14 53.0 0.0 4.9e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase MeaB PF03308.16 KEZ36680.1 - 0.0026 16.8 0.1 0.0036 16.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KEZ36680.1 - 0.0058 16.5 0.0 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KEZ36680.1 - 0.028 14.2 0.3 0.048 13.4 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ36680.1 - 0.15 12.6 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEZ36680.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Response_reg PF00072.24 KEZ36681.1 - 3.6e-28 98.0 0.0 4.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ36681.1 - 1.2e-26 92.6 0.0 1.7e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Glyco_transf_4 PF13439.6 KEZ36681.1 - 0.0022 18.0 0.8 2.5 8.0 0.1 3.1 3 0 0 3 3 3 2 Glycosyltransferase Family 4 FleQ PF06490.11 KEZ36681.1 - 0.099 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 KEZ36682.1 - 4.3e-24 85.2 0.0 7.1e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ36682.1 - 2.6e-17 62.6 1.5 4.6e-17 61.8 0.7 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ36682.1 - 1.4e-13 51.0 2.4 1.7e-13 50.7 0.4 2.3 2 0 0 2 2 2 1 HAMP domain WYL PF13280.6 KEZ36683.1 - 2.2e-38 132.0 0.1 3.6e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 KEZ36683.1 - 2e-15 56.5 0.2 4.8e-15 55.2 0.1 1.7 2 0 0 2 2 1 1 HTH domain HTH_DeoR PF08220.12 KEZ36683.1 - 6.5e-06 25.8 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KEZ36683.1 - 1.1e-05 25.6 0.1 2.3e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 KEZ36683.1 - 1.6e-05 24.7 0.2 4.6e-05 23.2 0.2 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 KEZ36683.1 - 1.9e-05 24.3 0.2 1.9e-05 24.3 0.2 2.1 2 0 0 2 2 1 1 Homeodomain-like domain HTH_29 PF13551.6 KEZ36683.1 - 0.0001 22.2 0.2 0.00029 20.8 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 KEZ36683.1 - 0.00012 21.6 0.2 0.00026 20.5 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KEZ36683.1 - 0.00022 21.2 0.6 0.00082 19.4 0.6 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KEZ36683.1 - 0.001 18.8 0.4 0.0034 17.2 0.4 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KEZ36683.1 - 0.002 18.0 0.1 0.0039 17.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 KEZ36683.1 - 0.0069 16.2 3.5 0.013 15.3 1.8 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ36683.1 - 0.0083 16.1 0.7 0.03 14.3 0.5 2.0 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KEZ36683.1 - 0.0096 16.0 0.1 0.0096 16.0 0.1 2.4 2 0 0 2 2 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KEZ36683.1 - 0.016 14.9 1.4 0.066 12.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 KEZ36683.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TetR_N PF00440.23 KEZ36683.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family GntR PF00392.21 KEZ36683.1 - 0.041 13.5 0.4 0.14 11.9 0.4 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KEZ36683.1 - 0.045 13.7 0.6 0.045 13.7 0.6 2.7 4 0 0 4 4 3 0 MarR family HTH_22 PF13309.6 KEZ36683.1 - 0.045 13.8 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 HTH domain Sigma70_ECF PF07638.11 KEZ36683.1 - 0.054 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 ECF sigma factor HTH_38 PF13936.6 KEZ36683.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 KEZ36683.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain FUR PF01475.19 KEZ36683.1 - 0.23 11.6 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family Glyoxalase_6 PF18029.1 KEZ36684.1 - 1.8e-21 76.9 0.2 2.7e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Amidohydro_2 PF04909.14 KEZ36685.1 - 2.1e-10 40.9 0.9 8.3e-10 38.9 0.0 2.2 2 1 0 3 3 3 1 Amidohydrolase Gln-synt_C PF00120.24 KEZ36686.1 - 9.1e-76 255.1 0.0 6.2e-45 153.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KEZ36686.1 - 3.4e-08 33.3 0.0 7.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Sacchrp_dh_NADP PF03435.18 KEZ36687.1 - 4.7e-11 43.1 0.3 9.4e-11 42.1 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KEZ36687.1 - 2.1e-06 27.7 4.5 2.1e-06 27.7 4.5 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KEZ36687.1 - 0.0003 20.9 0.1 0.00053 20.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KEZ36687.1 - 0.002 18.7 1.5 0.004 17.7 0.2 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KEZ36687.1 - 0.0033 17.0 4.7 0.0056 16.3 1.4 2.1 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KEZ36687.1 - 0.072 12.5 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEZ36687.1 - 0.11 12.0 1.5 0.12 11.8 0.7 1.5 2 0 0 2 2 2 0 short chain dehydrogenase CPSase_L_D2 PF02786.17 KEZ36688.1 - 1.4e-69 233.9 0.1 2.2e-69 233.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KEZ36688.1 - 2.2e-45 154.9 0.0 3.2e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KEZ36688.1 - 8.1e-38 129.4 0.0 2e-37 128.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ36688.1 - 3.6e-34 117.1 0.0 7.2e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KEZ36688.1 - 2.1e-23 83.2 0.2 4.6e-23 82.1 0.2 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KEZ36688.1 - 2e-17 62.8 0.8 4.3e-17 61.7 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KEZ36688.1 - 9.3e-08 31.9 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEZ36688.1 - 2.8e-07 30.3 0.0 7e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KEZ36688.1 - 4.2e-05 23.3 0.8 0.0074 16.1 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 KEZ36688.1 - 0.00031 20.6 0.8 0.00079 19.3 0.8 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 KEZ36688.1 - 0.001 19.0 0.3 0.002 18.0 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein NQRA PF05896.11 KEZ36688.1 - 0.01 15.3 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PYNP_C PF07831.13 KEZ36688.1 - 0.04 13.6 0.3 2.4 7.9 0.1 2.5 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_transf_2 PF00535.26 KEZ36689.1 - 1.3e-20 73.9 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 KEZ36689.1 - 8.2e-11 42.2 7.2 4e-09 36.7 9.3 2.1 1 1 1 2 2 2 2 GtrA-like protein Glyco_tranf_2_3 PF13641.6 KEZ36689.1 - 0.00074 19.5 0.1 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Polysacc_synt_C PF14667.6 KEZ36689.1 - 0.66 10.0 8.4 1.2 9.2 8.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PMT_2 PF13231.6 KEZ36690.1 - 3.1e-30 105.5 18.4 3.1e-30 105.5 18.4 3.2 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4175 PF13779.6 KEZ36690.1 - 3.8 5.3 4.9 9.6 4.0 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HATPase_c PF02518.26 KEZ36691.1 - 1.4e-21 77.1 0.0 2.5e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ36691.1 - 1.3e-17 63.5 0.5 2.9e-17 62.5 0.5 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ36691.1 - 3.1e-10 40.3 0.8 9.1e-10 38.8 0.8 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 KEZ36691.1 - 0.0096 15.9 0.0 0.033 14.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KEZ36691.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KEZ36691.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 GHKL domain Cloacin PF03515.14 KEZ36691.1 - 0.24 11.1 2.7 0.28 10.8 1.4 1.6 2 0 0 2 2 2 0 Colicin-like bacteriocin tRNase domain Virul_fac_BrkB PF03631.15 KEZ36691.1 - 2 8.0 9.2 0.25 10.9 3.2 2.4 2 1 0 2 2 2 0 Virulence factor BrkB Response_reg PF00072.24 KEZ36692.1 - 4.5e-31 107.3 0.0 6.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ36692.1 - 1.6e-26 92.2 0.0 2e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 KEZ36692.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ B12-binding PF02310.19 KEZ36692.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Lipase_GDSL_2 PF13472.6 KEZ36692.1 - 0.036 14.4 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 KEZ36694.1 - 3.7e-48 160.5 13.1 1.8e-08 34.9 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat HSP70 PF00012.20 KEZ36694.1 - 9.7e-32 109.9 0.0 2e-31 108.8 0.0 1.4 1 1 1 2 2 2 1 Hsp70 protein ANAPC4_WD40 PF12894.7 KEZ36694.1 - 4.2e-19 68.6 0.0 0.011 16.0 0.0 6.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ36694.1 - 3.4e-13 49.3 6.3 0.034 13.1 0.0 6.7 1 1 6 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ36694.1 - 2.9e-10 39.8 0.3 1.5 8.9 0.0 6.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KEZ36694.1 - 1.5e-09 37.4 5.5 3.1 7.6 0.0 7.1 7 0 0 7 7 7 4 Proteasome subunit A N-terminal signature TruB_C PF09142.11 KEZ36694.1 - 1.6e-06 27.8 2.5 4.8 7.0 0.0 6.7 5 1 1 6 6 6 1 tRNA Pseudouridine synthase II, C terminal eIF2A PF08662.11 KEZ36694.1 - 1e-05 25.6 0.0 4 7.3 0.0 4.0 1 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 KEZ36694.1 - 5.3e-05 22.9 0.3 0.078 12.5 0.0 3.2 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 KEZ36694.1 - 0.00011 21.9 8.0 0.0079 15.8 1.9 2.8 2 1 0 3 3 3 2 PQQ-like domain MreB_Mbl PF06723.13 KEZ36694.1 - 0.00036 19.5 0.3 0.0029 16.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein TGBp3 PF02495.17 KEZ36694.1 - 0.00041 19.9 0.1 11 5.7 0.0 4.4 4 0 0 4 4 4 2 Triple gene block 3 Nup160 PF11715.8 KEZ36694.1 - 0.0031 16.2 1.3 0.82 8.2 0.0 3.4 3 1 1 4 4 4 1 Nucleoporin Nup120/160 DUF5570 PF17731.1 KEZ36694.1 - 0.8 9.8 7.8 0.26 11.4 0.7 3.2 2 1 0 3 3 3 0 Family of unknown function (DUF5570) Response_reg PF00072.24 KEZ36696.1 - 2.4e-11 43.8 0.0 3.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 KEZ36696.1 - 0.0014 18.3 0.2 0.0025 17.4 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Peptidase_S32 PF05579.13 KEZ36696.1 - 0.032 13.4 0.2 0.051 12.8 0.2 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Sigma70_r4 PF04545.16 KEZ36696.1 - 0.044 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TetR_C_21 PF17926.1 KEZ36696.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GerE PF00196.19 KEZ36696.1 - 0.11 12.1 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family T7SS_ESX_EspC PF10824.8 KEZ36696.1 - 1 9.9 4.2 4.4 7.8 0.3 2.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm HATPase_c_2 PF13581.6 KEZ36697.1 - 4.3e-06 26.7 0.1 1.9e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ36697.1 - 0.00022 21.7 0.2 0.0026 18.3 0.0 2.7 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SBP_bac_11 PF13531.6 KEZ36699.1 - 1.6e-46 158.9 9.6 3.5e-46 157.8 9.6 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein VWA_2 PF13519.6 KEZ36699.1 - 0.0001 22.9 0.0 0.00032 21.3 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ36699.1 - 0.00013 22.2 0.0 0.00023 21.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KEZ36699.1 - 0.039 13.9 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain SBP_bac_6 PF13343.6 KEZ36699.1 - 0.044 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF3040 PF11239.8 KEZ36699.1 - 2.6 8.4 6.7 1.7 8.9 2.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) NTP_transf_3 PF12804.7 KEZ36700.1 - 3.1e-27 95.9 7.3 5.4e-27 95.1 7.3 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain MarR PF01047.22 KEZ36701.1 - 1.9e-14 53.3 0.0 5.8e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KEZ36701.1 - 3.3e-12 46.1 2.5 1.5e-11 44.0 1.6 2.2 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KEZ36701.1 - 6.4e-10 39.4 0.1 1.2e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 KEZ36701.1 - 7.3e-07 28.7 0.1 2.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KEZ36701.1 - 4.5e-05 23.3 0.0 0.00012 21.9 0.0 1.7 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 KEZ36701.1 - 0.00078 19.8 0.0 0.0016 18.8 0.0 1.6 1 1 0 1 1 1 1 Penicillinase repressor HTH_Crp_2 PF13545.6 KEZ36701.1 - 0.0036 17.3 0.3 0.0063 16.5 0.3 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 KEZ36701.1 - 0.015 15.1 0.9 0.053 13.3 0.1 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain RP-C PF03428.13 KEZ36701.1 - 0.018 14.7 1.2 0.035 13.8 1.2 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_20 PF12840.7 KEZ36701.1 - 0.024 14.7 0.8 0.73 9.9 0.1 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KEZ36701.1 - 0.035 13.9 4.9 0.058 13.2 0.3 2.7 3 0 0 3 3 2 0 AsnC-type helix-turn-helix domain TLP1_add_C PF18313.1 KEZ36701.1 - 0.053 13.5 0.3 2.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain FliT PF05400.13 KEZ36701.1 - 0.058 14.2 0.9 0.11 13.3 0.3 1.8 2 0 0 2 2 2 0 Flagellar protein FliT GntR PF00392.21 KEZ36701.1 - 0.063 12.9 0.2 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family PadR PF03551.14 KEZ36701.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TFIIE_alpha PF02002.17 KEZ36701.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_36 PF13730.6 KEZ36701.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 1 0 Helix-turn-helix domain AbiEi_4 PF13338.6 KEZ36701.1 - 0.12 12.5 1.9 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin NTP_transf_5 PF14907.6 KEZ36702.1 - 1.4e-06 28.1 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2204 PF09970.9 KEZ36702.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) BON PF04972.17 KEZ36702.1 - 4.6e-05 23.6 1.2 0.00012 22.3 1.2 1.8 1 0 0 1 1 1 1 BON domain DUF2007 PF09413.10 KEZ36702.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Metallophos PF00149.28 KEZ36703.1 - 1.2e-10 42.2 0.0 1.9e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ36703.1 - 6.1e-07 29.8 0.0 1.9e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rieske PF00355.26 KEZ36704.1 - 3.8e-13 49.2 0.0 6.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KEZ36704.1 - 6.2e-06 26.1 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF2231 PF09990.9 KEZ36704.1 - 0.083 13.3 0.8 0.16 12.5 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF998 PF06197.13 KEZ36704.1 - 2.3 7.8 12.3 5.3 6.6 12.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF2795 PF11387.8 KEZ36705.1 - 3.5e-11 43.1 0.0 8.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) Phage_holin_3_6 PF07332.11 KEZ36706.1 - 0.1 12.6 4.9 0.12 12.4 4.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CBP_CCPA PF17040.5 KEZ36706.1 - 0.24 12.0 1.2 0.39 11.3 1.1 1.4 1 1 0 1 1 1 0 Cellulose-complementing protein A Asparaginase_II PF06089.12 KEZ36709.1 - 1.4e-112 375.9 0.2 1.6e-112 375.7 0.2 1.0 1 0 0 1 1 1 1 L-asparaginase II Cm_res_leader PF08077.11 KEZ36709.1 - 1.8 8.9 7.9 1.4 9.3 0.7 4.1 4 0 0 4 4 4 0 Chloramphenicol resistance gene leader peptide DnaJ PF00226.31 KEZ36710.1 - 3.6e-15 55.8 0.0 5.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3099 PF11298.8 KEZ36710.1 - 0.00017 21.7 5.7 0.00037 20.6 5.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) MASE2 PF05230.11 KEZ36710.1 - 0.03 14.4 2.8 0.051 13.7 2.8 1.3 1 0 0 1 1 1 0 MASE2 domain CoA_transf_3 PF02515.17 KEZ36711.1 - 4.2e-48 164.3 0.9 1.6e-43 149.3 0.6 2.3 2 0 0 2 2 2 2 CoA-transferase family III Peripla_BP_6 PF13458.6 KEZ36712.1 - 4.7e-52 177.7 13.6 5.5e-52 177.5 13.6 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KEZ36712.1 - 2.3e-17 63.1 0.0 7.3e-17 61.5 0.0 1.7 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KEZ36712.1 - 1.6e-05 24.1 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LytR_C PF13399.6 KEZ36712.1 - 0.47 11.5 3.2 1.7 9.7 0.2 3.2 1 1 2 3 3 3 0 LytR cell envelope-related transcriptional attenuator BPD_transp_2 PF02653.16 KEZ36713.1 - 2e-39 135.4 36.5 2.5e-39 135.1 36.5 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component NDUF_B12 PF08122.12 KEZ36713.1 - 9.8 6.3 9.1 25 5.0 0.1 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family BPD_transp_2 PF02653.16 KEZ36714.1 - 3.6e-44 150.9 29.8 3.6e-44 150.9 29.8 2.2 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component DUF2301 PF10063.9 KEZ36714.1 - 6.7 7.1 9.2 0.62 10.5 1.3 2.9 3 1 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) ABC_tran PF00005.27 KEZ36715.1 - 1.6e-27 96.6 0.0 2.1e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 KEZ36715.1 - 1.9e-11 43.6 0.4 1.9e-11 43.6 0.4 2.1 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 KEZ36715.1 - 4.4e-06 26.7 0.5 0.00034 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ36715.1 - 0.00012 22.5 0.2 0.00023 21.6 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KEZ36715.1 - 0.00075 20.1 0.1 0.0011 19.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ36715.1 - 0.0022 18.2 0.0 0.096 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ36715.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ36715.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ36715.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KEZ36715.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KEZ36715.1 - 0.03 14.0 0.0 2.8 7.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PIF1 PF05970.14 KEZ36715.1 - 0.039 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase FeoB_N PF02421.18 KEZ36715.1 - 0.051 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B SMC_N PF02463.19 KEZ36715.1 - 0.071 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KEZ36715.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ36716.1 - 1.6e-29 103.2 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ36716.1 - 1.7e-09 38.0 0.3 0.00071 19.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 KEZ36716.1 - 0.0023 17.8 1.0 0.0031 17.4 0.1 1.8 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter AAA_29 PF13555.6 KEZ36716.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KEZ36716.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ36716.1 - 0.012 15.3 0.6 0.11 12.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEZ36716.1 - 0.021 15.2 0.3 0.048 14.0 0.2 1.8 1 1 1 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 KEZ36716.1 - 0.023 12.2 0.9 0.03 11.9 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mg_chelatase PF01078.21 KEZ36716.1 - 0.036 13.4 0.4 0.13 11.6 0.0 2.0 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KEZ36716.1 - 0.051 13.8 0.1 0.1 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEZ36716.1 - 0.071 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MukB PF04310.12 KEZ36716.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal SRP54 PF00448.22 KEZ36716.1 - 0.17 11.5 0.2 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 KEZ36716.1 - 0.25 10.7 0.0 17 4.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 KEZ36716.1 - 0.28 11.5 0.8 0.73 10.2 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ36716.1 - 0.33 11.4 0.1 0.46 11.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain ALO PF04030.14 KEZ36717.1 - 9.6e-74 248.5 0.0 1.1e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KEZ36717.1 - 1.3e-23 83.2 3.2 2.3e-23 82.5 3.2 1.4 1 0 0 1 1 1 1 FAD binding domain Acyl_transf_3 PF01757.22 KEZ36718.1 - 8.4e-24 84.3 32.7 9.8e-24 84.0 32.7 1.1 1 0 0 1 1 1 1 Acyltransferase family adh_short PF00106.25 KEZ36719.1 - 2.5e-44 151.1 0.1 3e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ36719.1 - 2.1e-32 112.6 1.3 2.5e-32 112.3 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ36719.1 - 1.7e-14 54.1 0.9 2.5e-14 53.6 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ36719.1 - 0.00012 21.6 0.3 0.00038 20.0 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ36719.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KEZ36719.1 - 0.038 13.1 0.1 0.073 12.2 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain E1-E2_ATPase PF00122.20 KEZ36720.1 - 1.1e-38 132.6 0.8 3.7e-38 130.9 0.8 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ36720.1 - 3.3e-22 79.8 4.2 3.4e-22 79.8 2.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KEZ36720.1 - 2.1e-19 69.9 0.1 3.7e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KEZ36720.1 - 8.2e-05 22.2 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KEZ36720.1 - 0.0037 17.3 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEZ36720.1 - 0.0051 16.6 0.2 0.068 12.9 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ36720.1 - 0.05 14.0 0.1 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KEZ36722.1 - 5.3e-48 163.1 0.0 7.1e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ36722.1 - 5.8e-34 117.7 0.0 7.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ36722.1 - 1.7e-08 34.6 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ36722.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ36722.1 - 0.015 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EFhand_Ca_insen PF08726.10 KEZ36722.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DFP PF04127.15 KEZ36722.1 - 0.21 11.4 0.5 0.64 9.8 0.5 1.7 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Bac_luciferase PF00296.20 KEZ36723.1 - 6.8e-35 121.0 7.0 9e-35 120.6 7.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TPR_16 PF13432.6 KEZ36724.1 - 5.1e-06 27.0 6.3 0.00012 22.7 0.5 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ36724.1 - 0.00061 20.4 6.4 0.033 15.0 0.0 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ36724.1 - 0.037 14.0 0.4 0.67 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ36724.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ36724.1 - 0.35 11.2 5.0 3.7 7.9 0.1 2.7 2 2 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane_2 PF12679.7 KEZ36725.1 - 0.032 13.5 0.7 0.48 9.6 0.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3792 PF12670.7 KEZ36726.1 - 0.014 15.5 6.9 0.53 10.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF3040 PF11239.8 KEZ36726.1 - 0.15 12.3 12.2 0.72 10.2 7.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3180 PF11377.8 KEZ36726.1 - 0.44 10.7 13.6 3.2 7.9 13.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) GtrA PF04138.14 KEZ36726.1 - 0.92 9.8 7.5 4.5 7.5 2.3 2.1 2 0 0 2 2 2 0 GtrA-like protein DUF5325 PF17259.2 KEZ36726.1 - 2.2 8.2 6.5 1.3 8.9 0.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5325) OmpA PF00691.20 KEZ36728.1 - 1.5e-14 54.1 0.0 2.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 OmpA family Tox-PL-2 PF15643.6 KEZ36728.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 Methyltransf_11 PF08241.12 KEZ36729.1 - 3.8e-20 72.3 0.1 5.9e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ36729.1 - 2.5e-18 66.6 0.2 3.9e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ36729.1 - 3.4e-10 39.9 0.0 4.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ36729.1 - 2.1e-09 37.1 0.0 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KEZ36729.1 - 9.4e-09 34.3 0.0 1.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 KEZ36729.1 - 4.3e-08 33.2 0.0 7.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ36729.1 - 5.3e-07 30.3 0.0 8.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEZ36729.1 - 0.00013 21.9 0.0 0.00066 19.6 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase ADH_zinc_N PF00107.26 KEZ36729.1 - 0.0018 18.3 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KEZ36729.1 - 0.02 14.5 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TPMT PF05724.11 KEZ36729.1 - 0.025 14.2 0.2 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KEZ36729.1 - 0.09 12.1 0.5 0.14 11.4 0.5 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pkinase PF00069.25 KEZ36730.1 - 1.3e-41 142.7 0.0 1.8e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36730.1 - 1.4e-20 73.7 0.0 1.7e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ36730.1 - 0.00072 19.5 7.2 0.0025 17.8 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ36730.1 - 0.0045 15.8 0.0 0.0067 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEZ36730.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KEZ36731.1 - 8.6e-39 133.5 0.0 1.2e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ36731.1 - 8.7e-25 87.5 0.0 1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ36731.1 - 3e-07 30.6 2.3 0.008 16.1 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family X PF00739.19 KEZ36731.1 - 0.92 9.6 0.0 0.92 9.6 0.0 2.5 2 1 1 3 3 3 0 Trans-activation protein X Pex14_N PF04695.13 KEZ36731.1 - 4 8.1 6.5 1.2 9.8 3.2 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NMT1_3 PF16868.5 KEZ36732.1 - 5.2e-23 81.9 0.0 1.6e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 KEZ36732.1 - 0.015 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 STT3 PF02516.14 KEZ36733.1 - 0.0027 16.7 3.7 0.0058 15.6 3.7 1.5 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Thioesterase PF00975.20 KEZ36736.1 - 2.9e-18 66.8 0.3 5.6e-18 65.9 0.3 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KEZ36736.1 - 1.8e-12 47.5 0.1 4.3e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ribosomal_L12_N PF16320.5 KEZ36736.1 - 0.14 11.9 0.3 0.46 10.2 0.3 1.8 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain adh_short_C2 PF13561.6 KEZ36737.1 - 3e-61 207.0 0.2 3.4e-61 206.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ36737.1 - 8.2e-52 175.5 0.1 9.6e-52 175.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ36737.1 - 1.8e-12 47.6 0.6 2.5e-12 47.1 0.6 1.1 1 0 0 1 1 1 1 KR domain GGDEF PF00990.21 KEZ36738.1 - 1.3e-77 259.1 0.0 5.6e-40 136.7 0.0 3.4 3 0 0 3 3 3 3 Diguanylate cyclase, GGDEF domain PAS PF00989.25 KEZ36738.1 - 6.7e-22 77.6 0.0 2.4e-10 40.4 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 KEZ36738.1 - 1.1e-15 57.6 0.0 2.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KEZ36738.1 - 3.8e-13 49.6 1.0 9.4e-06 25.8 0.0 3.8 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 KEZ36738.1 - 5.3e-11 42.7 0.0 0.00023 21.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 KEZ36738.1 - 0.00011 22.1 0.5 0.0092 16.0 0.0 3.6 3 0 0 3 3 3 1 PAS domain dCache_1 PF02743.18 KEZ36738.1 - 0.011 15.5 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Cache domain AidB_N PF18158.1 KEZ36739.1 - 1e-57 194.4 0.8 1e-57 194.4 0.8 1.8 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KEZ36739.1 - 1.9e-29 102.8 5.2 3.8e-29 101.8 5.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ36739.1 - 4.2e-18 65.3 0.0 8.4e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ36739.1 - 1.9e-11 44.3 2.7 1.9e-11 44.3 2.7 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PsiA PF06952.11 KEZ36739.1 - 0.11 11.7 1.1 0.24 10.6 0.7 1.7 2 0 0 2 2 2 0 PsiA protein DUF1118 PF06549.12 KEZ36743.1 - 0.047 14.0 5.6 0.69 10.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Cys_Met_Meta_PP PF01053.20 KEZ36744.1 - 1.4e-135 451.7 0.0 1.6e-135 451.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ36744.1 - 3e-05 23.5 0.1 4.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEZ36744.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PALP PF00291.25 KEZ36745.1 - 1.4e-68 231.4 0.2 2.1e-68 230.9 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KEZ36745.1 - 1.2e-10 41.7 0.2 0.00036 20.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain Glyco_transf_4 PF13439.6 KEZ36745.1 - 0.012 15.6 0.3 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 Glycosyltransferase Family 4 YccF PF03733.13 KEZ36746.1 - 4.4e-35 120.2 32.7 1.7e-17 63.9 13.9 2.2 2 0 0 2 2 2 2 Inner membrane component domain DUF2189 PF09955.9 KEZ36746.1 - 0.019 15.2 5.3 0.23 11.7 1.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) PRA1 PF03208.19 KEZ36746.1 - 0.25 11.0 7.9 0.37 10.4 7.9 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF3930 PF13067.6 KEZ36746.1 - 0.39 11.0 2.0 7.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) GGDEF PF00990.21 KEZ36747.1 - 2.4e-41 141.2 0.0 4.2e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain EAL PF00563.20 KEZ36747.1 - 3.7e-36 124.8 0.0 9.5e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 EAL domain GAF PF01590.26 KEZ36747.1 - 4.6e-15 56.4 5.0 3.9e-09 37.2 0.5 3.1 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 KEZ36747.1 - 1.4e-09 38.4 6.4 1.9e-09 38.0 1.4 3.0 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KEZ36747.1 - 2.6e-06 27.8 0.5 1.2e-05 25.6 0.2 2.4 2 0 0 2 2 2 1 GAF domain ABC_membrane PF00664.23 KEZ36748.1 - 2.4e-42 145.5 12.8 3.1e-42 145.1 12.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ36748.1 - 1.6e-25 90.2 0.0 2.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ36748.1 - 5.5e-05 22.7 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ36748.1 - 0.0016 18.9 0.2 0.0045 17.4 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEZ36748.1 - 0.0079 15.9 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KEZ36748.1 - 0.017 14.0 1.4 0.12 11.2 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 KEZ36748.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KEZ36748.1 - 0.039 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KEZ36748.1 - 0.096 13.2 0.3 0.16 12.4 0.3 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KEZ36748.1 - 0.1 12.7 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_21 PF13304.6 KEZ36748.1 - 0.25 11.1 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 KEZ36749.1 - 1.4e-56 192.2 3.1 1.9e-56 191.8 3.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ36749.1 - 2.3e-29 102.6 0.0 4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KEZ36749.1 - 0.00024 21.5 0.1 0.0012 19.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KEZ36749.1 - 0.00042 19.8 0.0 0.064 12.7 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEZ36749.1 - 0.00085 19.1 0.6 0.002 17.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEZ36749.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KEZ36749.1 - 0.0033 18.0 0.0 0.0058 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ36749.1 - 0.0056 17.0 0.1 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEZ36749.1 - 0.0059 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KEZ36749.1 - 0.0085 15.1 1.6 0.019 13.9 1.6 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KEZ36749.1 - 0.022 15.2 0.0 0.15 12.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEZ36749.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEZ36749.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KEZ36749.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KEZ36749.1 - 0.059 12.9 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KEZ36749.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KEZ36749.1 - 0.076 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KEZ36749.1 - 0.11 12.8 0.2 0.3 11.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ36749.1 - 0.13 12.5 0.5 0.44 10.8 0.2 1.9 1 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KEZ36749.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 KEZ36749.1 - 0.15 11.8 0.5 0.7 9.6 0.5 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 KEZ36749.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Phage_holin_3_6 PF07332.11 KEZ36749.1 - 9.9 6.2 14.0 44 4.2 7.6 3.2 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Peripla_BP_6 PF13458.6 KEZ36750.1 - 2.2e-39 136.1 2.4 3.9e-39 135.3 2.4 1.4 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KEZ36750.1 - 6.8e-06 25.4 0.0 6.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_4 PF13407.6 KEZ36750.1 - 0.014 14.9 0.8 0.24 11.0 0.2 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain BPD_transp_2 PF02653.16 KEZ36751.1 - 2.7e-44 151.3 76.0 1.2e-23 83.6 34.3 2.2 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 KEZ36752.1 - 4.8e-55 185.8 0.0 5.5e-28 98.2 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEZ36752.1 - 3.4e-21 76.4 9.1 1.9e-06 27.9 0.3 4.1 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ36752.1 - 2.8e-10 39.8 3.6 5.6e-05 22.8 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ36752.1 - 9.3e-10 39.3 1.8 2.6e-05 24.8 1.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEZ36752.1 - 1.3e-07 32.2 5.6 0.0038 17.6 1.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain BCA_ABC_TP_C PF12399.8 KEZ36752.1 - 2e-07 30.7 1.1 2e-07 30.7 1.1 1.9 2 0 0 2 2 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_22 PF13401.6 KEZ36752.1 - 2.2e-07 31.2 0.7 0.033 14.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEZ36752.1 - 1.1e-06 28.6 0.3 0.0047 16.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KEZ36752.1 - 2.6e-06 27.4 0.0 0.0037 17.0 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 KEZ36752.1 - 1.1e-05 25.0 3.9 0.02 14.3 0.1 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KEZ36752.1 - 2.1e-05 24.9 0.4 0.3 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ36752.1 - 3.4e-05 23.6 7.8 0.019 14.7 0.6 3.0 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KEZ36752.1 - 0.00023 21.2 0.6 0.34 11.0 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 KEZ36752.1 - 0.00065 19.9 0.3 1.4 9.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KEZ36752.1 - 0.001 18.4 1.6 0.026 13.8 0.1 2.2 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 KEZ36752.1 - 0.0011 19.0 2.6 0.31 11.1 0.2 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KEZ36752.1 - 0.0017 18.8 0.5 1 9.8 0.1 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEZ36752.1 - 0.0043 16.6 6.4 1.5 8.3 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_27 PF13514.6 KEZ36752.1 - 0.0049 16.5 0.4 1.5 8.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KEZ36752.1 - 0.0054 16.9 0.0 3.4 8.0 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KEZ36752.1 - 0.0072 16.1 1.4 2.2 7.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KEZ36752.1 - 0.0087 15.7 3.1 0.72 9.4 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KEZ36752.1 - 0.0099 15.7 1.1 0.35 10.6 0.3 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KEZ36752.1 - 0.01 16.4 1.0 5.7 7.5 0.2 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KEZ36752.1 - 0.012 15.6 1.1 3 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KEZ36752.1 - 0.012 15.2 4.9 0.81 9.2 1.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KEZ36752.1 - 0.013 14.5 3.6 1.1 8.2 0.3 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KEZ36752.1 - 0.015 15.2 0.5 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 KEZ36752.1 - 0.015 14.7 0.6 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KEZ36752.1 - 0.016 15.2 0.1 4.7 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KEZ36752.1 - 0.019 14.9 1.9 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain MukB PF04310.12 KEZ36752.1 - 0.024 14.5 2.6 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal KdpD PF02702.17 KEZ36752.1 - 0.027 13.9 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain IstB_IS21 PF01695.17 KEZ36752.1 - 0.037 13.7 1.2 2.6 7.7 0.1 3.0 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 KEZ36752.1 - 0.042 14.2 2.5 3.3 8.0 0.3 2.9 2 1 0 2 2 2 0 AAA domain DLIC PF05783.11 KEZ36752.1 - 0.043 12.6 0.8 2.1 7.1 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ATP-synt_ab PF00006.25 KEZ36752.1 - 0.044 13.4 0.4 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 KEZ36752.1 - 0.055 12.1 0.6 6.7 5.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KEZ36752.1 - 0.056 13.2 1.8 3.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KEZ36752.1 - 0.066 13.1 0.7 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KEZ36752.1 - 0.091 13.0 1.1 13 6.0 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 KEZ36752.1 - 0.12 12.0 0.3 0.96 9.1 0.1 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEZ36752.1 - 0.25 10.5 2.6 5.2 6.2 0.4 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KEZ36752.1 - 0.28 11.6 0.7 8.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KEZ36752.1 - 0.35 10.4 1.4 5.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 KEZ36752.1 - 0.35 10.3 0.4 25 4.3 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3584 PF12128.8 KEZ36752.1 - 4.5 4.7 6.4 1.2 6.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ThiC_Rad_SAM PF01964.18 KEZ36753.1 - 2.3e-199 662.5 0.0 2.7e-199 662.2 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 KEZ36753.1 - 7.2e-22 77.0 0.2 2.4e-21 75.3 0.2 2.0 1 0 0 1 1 1 1 ThiC-associated domain ABATE PF07336.11 KEZ36754.1 - 1e-09 39.1 2.0 1.1e-09 39.0 2.0 1.0 1 0 0 1 1 1 1 Putative stress-induced transcription regulator HTH_26 PF13443.6 KEZ36755.1 - 8.6e-17 61.3 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 KEZ36755.1 - 0.00017 21.8 0.5 0.00031 21.0 0.2 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ36755.1 - 0.0069 16.4 0.0 0.0088 16.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix DUF433 PF04255.14 KEZ36757.1 - 6.7e-21 73.9 0.1 8.7e-21 73.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF433) DUF5615 PF18480.1 KEZ36758.1 - 6.5e-15 54.7 0.0 9.1e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) Phage_integrase PF00589.22 KEZ36758.1 - 0.0018 18.1 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family PIN_10 PF18478.1 KEZ36758.1 - 0.0032 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Mut7-C PF01927.16 KEZ36758.1 - 0.092 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain Phage_integrase PF00589.22 KEZ36759.1 - 3.9e-12 46.3 0.0 5.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Gp49 PF05973.14 KEZ36760.1 - 2.2e-21 75.8 0.0 2.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) HTH_31 PF13560.6 KEZ36761.1 - 3.4e-12 46.5 0.9 5.6e-12 45.8 0.9 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ36761.1 - 8.8e-12 44.9 0.1 1.4e-11 44.2 0.1 1.4 1 1 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 KEZ36761.1 - 3.9e-10 39.5 0.0 4.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ36761.1 - 5.8e-09 35.8 0.0 8.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ36761.1 - 1.6e-06 27.8 0.2 3.7e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ36761.1 - 1.8e-05 24.2 0.1 3.8e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KEZ36761.1 - 0.0024 17.6 0.1 0.0062 16.3 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain MqsA_antitoxin PF15731.5 KEZ36761.1 - 0.018 15.2 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_Crp_2 PF13545.6 KEZ36761.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Pou PF00157.17 KEZ36761.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DDE_5 PF13546.6 KEZ36762.1 - 0.00011 21.7 1.2 0.00023 20.6 0.0 2.0 2 1 1 3 3 3 1 DDE superfamily endonuclease GFO_IDH_MocA PF01408.22 KEZ36763.1 - 3.1e-22 79.6 0.2 3.9e-21 76.1 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.26 KEZ36763.1 - 5.9e-06 26.3 2.4 2.2e-05 24.4 0.2 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase F420_oxidored PF03807.17 KEZ36763.1 - 0.0024 18.4 2.2 0.23 12.0 0.1 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEZ36763.1 - 0.0038 16.6 0.1 0.032 13.6 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KEZ36763.1 - 0.005 17.5 0.3 0.016 15.8 0.3 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEZ36763.1 - 0.011 15.1 2.8 0.02 14.2 2.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 KEZ36763.1 - 0.012 16.1 0.0 0.044 14.2 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ36763.1 - 0.034 14.4 2.7 2.8 8.2 0.1 2.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KEZ36763.1 - 0.07 13.6 1.1 0.47 10.9 0.4 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 KEZ36763.1 - 0.14 12.4 2.6 0.16 12.2 0.6 2.2 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KEZ36763.1 - 0.19 11.6 0.3 0.36 10.7 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 KEZ36763.1 - 0.3 11.0 1.2 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Glycos_transf_4 PF00953.21 KEZ36764.1 - 2.2e-28 99.2 13.0 2.2e-28 99.2 13.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 Glyco_trans_4_4 PF13579.6 KEZ36765.1 - 1.6e-22 80.7 10.2 1.6e-22 80.7 10.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ36765.1 - 2.5e-19 69.9 1.5 6.1e-19 68.7 1.5 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEZ36765.1 - 2.2e-16 60.5 1.2 6.9e-16 58.9 0.7 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ36765.1 - 4.4e-13 49.1 0.0 6.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ36765.1 - 9.1e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 NAD_binding_10 PF13460.6 KEZ36766.1 - 4.3e-20 72.4 0.4 1e-19 71.1 0.4 1.8 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ36766.1 - 3.7e-18 65.9 0.2 1e-11 44.7 0.1 3.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ36766.1 - 2.8e-12 46.7 0.0 5.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Methyltransf_21 PF05050.12 KEZ36766.1 - 2.6e-08 34.1 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain RmlD_sub_bind PF04321.17 KEZ36766.1 - 3.6e-08 32.8 0.1 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEZ36766.1 - 1.3e-07 31.3 0.0 4.4e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ36766.1 - 1.6e-06 27.4 0.0 0.0028 16.7 0.0 2.8 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ36766.1 - 0.00028 20.2 0.2 0.0096 15.1 0.1 2.2 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 KEZ36766.1 - 0.0018 18.5 0.1 0.0048 17.1 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KEZ36766.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase LpxI_N PF17930.1 KEZ36766.1 - 0.12 12.3 0.0 0.58 10.1 0.0 2.2 2 1 0 2 2 2 0 LpxI N-terminal domain Glyco_trans_1_4 PF13692.6 KEZ36767.1 - 1.1e-08 35.6 0.1 3.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ36767.1 - 2.1e-07 30.6 0.0 4.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ36767.1 - 0.024 14.6 0.5 0.084 12.9 0.0 2.2 2 2 0 2 2 2 0 Glycosyltransferase Family 4 Glycos_transf_2 PF00535.26 KEZ36768.1 - 2.8e-11 43.5 0.1 5.3e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 KEZ36768.1 - 9.9e-06 26.0 0.3 2.9e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Hepar_II_III PF07940.13 KEZ36769.1 - 1.2e-56 192.0 9.1 2.2e-56 191.1 9.1 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein Hepar_II_III_N PF16889.5 KEZ36769.1 - 1.5e-07 31.0 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Heparinase II/III N-terminus Methyltransf_21 PF05050.12 KEZ36770.1 - 1.6e-16 60.8 0.0 2.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 KEZ36770.1 - 0.32 10.3 0.0 2.2 7.5 0.0 1.9 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein Adeno_PX PF05829.12 KEZ36770.1 - 8.3 6.4 9.2 0.28 11.1 0.8 2.3 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) Glyco_tranf_2_3 PF13641.6 KEZ36771.1 - 1.6e-09 38.0 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ36771.1 - 0.00014 21.9 0.2 0.00019 21.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 NTP_transf_3 PF12804.7 KEZ36771.1 - 0.0011 19.4 0.4 0.0016 18.8 0.4 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Methyltransf_21 PF05050.12 KEZ36772.1 - 6.1e-10 39.4 0.0 8.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_24 PF13578.6 KEZ36772.1 - 0.029 15.4 0.0 0.064 14.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 KEZ36772.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PolyA_pol PF01743.20 KEZ36772.1 - 0.058 13.8 0.1 6.1 7.3 0.0 2.9 1 1 1 3 3 3 0 Poly A polymerase head domain Met_10 PF02475.16 KEZ36774.1 - 0.033 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_21 PF05050.12 KEZ36774.1 - 0.26 11.3 0.0 16 5.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase FkbM domain GDP_Man_Dehyd PF16363.5 KEZ36775.1 - 5.7e-49 167.3 0.0 2.1e-48 165.4 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ36775.1 - 1.2e-47 162.4 0.0 1.7e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ36775.1 - 6.3e-10 38.5 0.0 8.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEZ36775.1 - 7e-06 25.4 0.0 0.008 15.3 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEZ36775.1 - 1.3e-05 24.4 0.0 3.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEZ36775.1 - 5e-05 22.6 0.0 0.095 11.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEZ36775.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEZ36775.1 - 0.07 13.0 0.3 0.18 11.7 0.0 1.8 3 0 0 3 3 3 0 KR domain Glycos_transf_1 PF00534.20 KEZ36776.1 - 1.1e-17 64.1 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ36776.1 - 9.4e-15 55.2 0.1 2.1e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ36776.1 - 7.9e-05 23.2 8.1 7.9e-05 23.2 8.1 2.8 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ36776.1 - 0.01 16.2 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 TylF PF05711.11 KEZ36777.1 - 1.1e-111 372.2 0.0 1.5e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 KEZ36777.1 - 3.4e-07 31.2 0.0 9.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_3 PF13440.6 KEZ36777.1 - 4.3e-05 22.9 1.1 4.3e-05 22.9 1.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 KEZ36777.1 - 0.0067 15.8 1.0 0.0067 15.8 1.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein LMWPc PF01451.21 KEZ36778.1 - 2.6e-17 63.5 0.0 4.3e-06 27.2 0.1 3.1 2 1 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase GFO_IDH_MocA PF01408.22 KEZ36779.1 - 8.1e-08 33.1 0.0 1.6e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold EAL PF00563.20 KEZ36780.1 - 2.4e-68 230.2 0.0 3.1e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KEZ36780.1 - 2.8e-31 108.4 0.0 4.3e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 KEZ36780.1 - 0.32 11.3 5.1 0.086 13.1 0.5 2.4 3 0 0 3 3 3 0 GGDEF-like domain Sortase PF04203.13 KEZ36781.1 - 9.1e-12 44.9 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Sortase domain Glyco_tranf_2_3 PF13641.6 KEZ36782.1 - 2e-05 24.6 0.1 8e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ36782.1 - 0.019 14.9 0.4 0.033 14.1 0.4 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 GlcNAc PF11397.8 KEZ36782.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Methyltransf_23 PF13489.6 KEZ36783.1 - 3.4e-20 72.5 0.0 4.7e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ36783.1 - 1.3e-14 54.6 0.1 2.9e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KEZ36783.1 - 1.8e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 KEZ36783.1 - 1e-09 39.0 0.0 2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ36783.1 - 6.3e-09 36.5 0.0 2.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ36783.1 - 3.7e-07 30.0 0.0 7.2e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ36783.1 - 0.0046 16.5 0.1 1.1 8.8 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase small domain TehB PF03848.14 KEZ36783.1 - 0.0063 15.9 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KEZ36783.1 - 0.034 13.5 0.0 0.07 12.4 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family AP_endonuc_2 PF01261.24 KEZ36783.1 - 0.12 11.8 0.1 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DREV PF05219.12 KEZ36783.1 - 0.19 10.8 0.1 0.3 10.1 0.0 1.3 2 0 0 2 2 2 0 DREV methyltransferase Glycos_transf_1 PF00534.20 KEZ36784.1 - 2.7e-14 53.1 0.0 4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ36784.1 - 1.2e-13 51.7 0.0 2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ36784.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Sigma70_r3 PF04539.16 KEZ36785.1 - 1.2e-32 111.8 1.5 2.4e-31 107.7 0.7 2.8 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 KEZ36785.1 - 2.4e-23 81.7 0.3 4.2e-23 80.9 0.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KEZ36785.1 - 2.7e-21 74.8 7.1 4e-20 71.1 0.9 3.4 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 KEZ36785.1 - 1.7e-19 69.5 0.1 1.7e-19 69.5 0.1 2.2 2 0 0 2 2 1 1 Sigma-70 factor, region 1.2 Sigma70_r1_1 PF03979.14 KEZ36785.1 - 1.6e-13 50.5 2.8 4.9e-13 48.9 1.0 2.3 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 HTH_15 PF12324.8 KEZ36785.1 - 0.0045 16.9 0.2 1.8 8.6 0.0 3.6 3 1 0 3 3 3 1 Helix-turn-helix domain of alkylmercury lyase MarR_2 PF12802.7 KEZ36785.1 - 0.0059 16.5 0.0 0.5 10.3 0.0 2.9 2 0 0 2 2 2 1 MarR family Put_DNA-bind_N PF06971.13 KEZ36785.1 - 0.0064 16.5 0.2 7.5 6.7 0.0 3.4 3 0 0 3 3 3 1 Putative DNA-binding protein N-terminus Exonuc_VII_L PF02601.15 KEZ36785.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit HTH_28 PF13518.6 KEZ36785.1 - 0.013 15.6 0.1 2 8.6 0.0 3.0 3 1 0 3 3 3 0 Helix-turn-helix domain DUF2316 PF10078.9 KEZ36785.1 - 0.015 15.5 0.5 2 8.7 0.0 3.7 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) Multi_ubiq PF14452.6 KEZ36785.1 - 0.033 14.4 0.6 4.8 7.5 0.1 3.6 2 1 1 3 3 3 0 Multiubiquitin CENP-B_N PF04218.13 KEZ36785.1 - 0.052 13.2 0.0 21 4.9 0.0 3.0 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain LexA_DNA_bind PF01726.16 KEZ36785.1 - 0.057 13.2 0.3 4.7 7.1 0.1 2.9 3 0 0 3 3 3 0 LexA DNA binding domain PolyA_pol_arg_C PF12626.7 KEZ36785.1 - 0.1 12.7 0.7 0.26 11.3 0.7 1.6 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus tify PF06200.14 KEZ36785.1 - 0.13 11.6 0.2 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 tify domain DUF2408 PF10303.9 KEZ36785.1 - 0.14 12.7 0.7 0.43 11.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Toprim_N PF08275.11 KEZ36786.1 - 9.5e-36 122.7 0.0 1.5e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 KEZ36786.1 - 6.3e-26 90.0 0.0 1.6e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 KEZ36786.1 - 2.3e-22 79.9 0.6 5e-22 78.8 0.1 1.8 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding Toprim_4 PF13662.6 KEZ36786.1 - 4.9e-17 62.2 0.2 1.2e-16 60.9 0.2 1.7 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 KEZ36786.1 - 3.4e-15 56.0 1.6 3.7e-14 52.7 0.2 3.0 2 0 0 2 2 2 1 DnaB-helicase binding domain of primase Toprim_2 PF13155.6 KEZ36786.1 - 3.6e-10 40.1 0.0 1.1e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 KEZ36786.1 - 3.2e-07 30.5 0.0 6.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 KEZ36786.1 - 5.6e-06 26.6 0.0 1.7e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain DUF5010 PF16402.5 KEZ36786.1 - 0.069 12.0 0.0 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HD_assoc PF13286.6 KEZ36788.1 - 3.5e-19 69.1 0.5 7.4e-19 68.1 0.5 1.6 1 0 0 1 1 1 1 Phosphohydrolase-associated domain HD PF01966.22 KEZ36788.1 - 9.9e-18 64.5 0.1 2.6e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 KEZ36788.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 HDOD domain bPH_2 PF03703.14 KEZ36790.1 - 1.4e-14 54.0 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 KEZ36790.1 - 0.033 14.6 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain DUF1211 PF06736.11 KEZ36790.1 - 0.035 14.6 4.1 0.037 14.5 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) DUF4079 PF13301.6 KEZ36790.1 - 0.13 12.4 2.0 0.18 12.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4636 PF15468.6 KEZ36790.1 - 0.18 11.5 0.8 0.24 11.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Transketolase_N PF00456.21 KEZ36791.1 - 4.9e-38 130.9 0.0 8.7e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEZ36791.1 - 1.1e-32 113.2 0.7 1.9e-32 112.4 0.7 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ36791.1 - 8.7e-28 96.7 0.3 2.3e-27 95.3 0.3 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KEZ36791.1 - 1.1e-07 31.1 0.0 1.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KEZ36791.1 - 1e-06 28.6 1.3 7.4e-05 22.6 0.2 3.5 2 2 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KEZ36791.1 - 7.6e-06 25.3 0.0 0.0017 17.6 0.0 2.6 2 1 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase DUF218 PF02698.17 KEZ36792.1 - 8e-26 90.6 0.0 1.1e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain CDP-OH_P_tran_2 PF08009.11 KEZ36792.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 PEP-utilizers_C PF02896.18 KEZ36793.1 - 1.1e-80 270.9 0.0 1.6e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 KEZ36793.1 - 3.6e-54 184.2 0.0 1.8e-38 132.7 0.0 3.1 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KEZ36793.1 - 9.9e-24 82.9 2.0 1.2e-23 82.6 0.8 1.8 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain tRNA_synt_2f PF02092.17 KEZ36794.1 - 4.1e-169 563.9 0.0 5.5e-169 563.5 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.15 KEZ36794.1 - 2.6e-125 417.3 0.0 3.7e-125 416.8 0.0 1.2 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit DALR_1 PF05746.15 KEZ36794.1 - 0.01 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 DALR anticodon binding domain DUF4872 PF16169.5 KEZ36794.1 - 0.38 10.5 4.4 7.5 6.3 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) ABM PF03992.16 KEZ36795.1 - 6.3e-05 23.0 0.0 9.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Prenyltransf PF01255.19 KEZ36796.1 - 6.2e-74 248.3 0.0 7.2e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RecO_C PF02565.15 KEZ36797.1 - 7.5e-31 107.0 0.6 1e-30 106.6 0.6 1.1 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 KEZ36797.1 - 1.3e-24 86.0 0.0 2.3e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Recombination protein O N terminal RecO_N_2 PF13114.6 KEZ36797.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 RecO N terminal Auto_anti-p27 PF06677.12 KEZ36797.1 - 0.018 15.2 1.3 0.044 13.9 1.3 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Anti-TRAP PF15777.5 KEZ36797.1 - 0.02 14.9 1.0 0.04 13.9 1.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-TFIIB PF13453.6 KEZ36797.1 - 0.56 9.6 3.0 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger MMR_HSR1 PF01926.23 KEZ36798.1 - 7.8e-20 71.1 0.0 1.2e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 KEZ36798.1 - 3.5e-15 55.6 0.0 5.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.23 KEZ36798.1 - 1.1e-09 38.6 0.1 0.00094 19.3 0.2 2.2 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 KEZ36798.1 - 4.9e-07 29.4 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KEZ36798.1 - 9.3e-06 25.4 0.0 3.2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 KEZ36798.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KEZ36798.1 - 2.3e-05 24.4 0.0 0.00067 19.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEZ36798.1 - 0.013 15.0 0.2 1.2 8.7 0.2 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KEZ36798.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KEZ36798.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit dCMP_cyt_deam_2 PF08211.12 KEZ36799.1 - 0.0082 16.3 0.7 0.011 16.0 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF21 PF01595.20 KEZ36800.1 - 3.9e-29 101.6 0.5 6e-29 101.0 0.5 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEZ36800.1 - 2.5e-13 50.2 2.9 2e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 KEZ36800.1 - 2.1e-11 43.7 0.4 1.1e-10 41.3 0.0 2.3 3 0 0 3 3 3 1 Transporter associated domain UPF0054 PF02130.17 KEZ36801.1 - 7.4e-38 129.3 0.0 8.9e-38 129.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Collagen PF01391.18 KEZ36801.1 - 0.13 12.0 21.0 0.31 10.8 21.0 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PhoH PF02562.16 KEZ36802.1 - 3.7e-90 300.9 0.0 5.2e-90 300.4 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 KEZ36802.1 - 1.7e-10 40.9 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ36802.1 - 2.3e-07 31.3 0.0 5.9e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ36802.1 - 7e-05 23.1 0.1 0.0065 16.8 0.1 3.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEZ36802.1 - 0.00018 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.12 KEZ36802.1 - 0.00097 18.8 0.0 0.0062 16.2 0.0 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) UvrD-helicase PF00580.21 KEZ36802.1 - 0.0018 17.9 0.7 0.49 9.9 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KEZ36802.1 - 0.0043 16.8 0.1 0.09 12.5 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.29 KEZ36802.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 KH domain AAA_25 PF13481.6 KEZ36802.1 - 0.1 12.2 0.1 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KEZ36802.1 - 0.17 11.9 0.1 0.29 11.1 0.1 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 KEZ36802.1 - 0.23 10.6 0.1 0.62 9.2 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Methyltrans_RNA PF04452.14 KEZ36803.1 - 1.8e-51 174.7 0.4 2e-51 174.5 0.4 1.0 1 0 0 1 1 1 1 RNA methyltransferase DnaJ_C PF01556.18 KEZ36804.1 - 5.5e-40 136.9 0.0 7.1e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ36804.1 - 1.3e-24 86.1 0.2 1.9e-24 85.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ36804.1 - 4.7e-13 49.3 15.3 7.7e-13 48.6 15.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ36804.1 - 0.59 10.1 18.2 1.9 8.5 5.4 3.1 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 KEZ36804.1 - 4.9 7.6 7.2 11 6.4 2.6 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar HrcA PF01628.21 KEZ36805.1 - 3.1e-60 203.8 0.1 4.3e-60 203.4 0.1 1.2 1 0 0 1 1 1 1 HrcA protein C terminal domain HTH_DeoR PF08220.12 KEZ36805.1 - 5e-06 26.2 0.0 4.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KEZ36805.1 - 9.7e-05 22.2 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 HTH domain HrcA_DNA-bdg PF03444.15 KEZ36805.1 - 0.00029 20.4 0.0 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Fe_dep_repress PF01325.19 KEZ36805.1 - 0.00083 19.5 0.0 0.0031 17.7 0.0 2.0 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KEZ36805.1 - 0.0013 18.7 0.0 0.0045 17.0 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.10 KEZ36805.1 - 0.0033 17.3 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain HTH_24 PF13412.6 KEZ36805.1 - 0.021 14.4 0.1 0.11 12.1 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KEZ36805.1 - 0.022 14.6 0.9 0.2 11.5 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain RuvB_C PF05491.13 KEZ36805.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain DprA_WH PF17782.1 KEZ36805.1 - 0.29 11.3 3.1 7.4 6.8 0.1 3.2 3 0 0 3 3 3 0 DprA winged helix domain Radical_SAM PF04055.21 KEZ36806.1 - 2.4e-18 67.1 0.0 4.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 KEZ36806.1 - 0.037 14.1 2.1 2.4 8.3 0.1 3.0 3 0 0 3 3 3 0 HemN C-terminal domain TetR_C_33 PF13305.6 KEZ36806.1 - 0.048 14.4 1.9 0.087 13.6 0.6 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Radical_SAM_C PF16199.5 KEZ36807.1 - 0.16 12.0 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Radical_SAM C-terminal domain GTP_EFTU PF00009.27 KEZ36808.1 - 1.6e-50 171.4 0.0 2.4e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KEZ36808.1 - 5.2e-49 164.9 0.6 8.3e-49 164.2 0.6 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KEZ36808.1 - 1.5e-19 69.8 0.0 4.5e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEZ36808.1 - 1.8e-06 28.3 2.1 1.8e-06 28.3 0.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ36808.1 - 4.6e-05 23.5 0.0 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KEZ36808.1 - 0.0037 17.3 0.0 0.014 15.4 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 KEZ36808.1 - 0.036 13.7 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Ras family RF3_C PF16658.5 KEZ36808.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain RsgA_GTPase PF03193.16 KEZ36808.1 - 0.12 12.2 0.0 0.49 10.3 0.0 2.0 2 1 1 3 3 3 0 RsgA GTPase SRPRB PF09439.10 KEZ36808.1 - 0.19 11.1 0.0 0.52 9.7 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ribosomal_S20p PF01649.18 KEZ36809.1 - 2.9e-26 91.9 11.7 3.3e-26 91.7 11.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S20 DUF4398 PF14346.6 KEZ36809.1 - 0.013 16.1 2.0 0.028 15.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DNA_pol3_delta PF06144.13 KEZ36811.1 - 3.1e-06 27.1 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 KEZ36811.1 - 0.033 14.1 1.4 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III YAcAr PF10686.9 KEZ36811.1 - 0.41 10.6 0.0 0.41 10.6 0.0 3.0 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family Competence PF03772.16 KEZ36812.1 - 8.2e-49 166.3 30.0 1.6e-48 165.4 30.0 1.5 1 0 0 1 1 1 1 Competence protein Lactamase_B PF00753.27 KEZ36812.1 - 3.5e-12 46.8 2.1 3.5e-12 46.8 2.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ36812.1 - 1.7e-09 37.5 0.3 3.7e-09 36.4 0.3 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4131 PF13567.6 KEZ36812.1 - 0.0088 15.7 0.5 0.0088 15.7 0.5 5.1 3 2 1 4 4 4 1 Domain of unknown function (DUF4131) HHH_3 PF12836.7 KEZ36813.1 - 2.9e-20 72.3 0.0 4.1e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif SLBB PF10531.9 KEZ36813.1 - 6e-12 45.3 2.0 1.3e-11 44.1 2.0 1.6 1 0 0 1 1 1 1 SLBB domain HHH PF00633.23 KEZ36813.1 - 1.6e-09 37.1 0.1 7e-06 25.7 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KEZ36813.1 - 0.00011 22.8 0.0 0.00051 20.6 0.0 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KEZ36813.1 - 0.00089 19.3 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_6 PF14579.6 KEZ36813.1 - 0.0033 17.6 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.11 KEZ36813.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Transposase_20 PF02371.16 KEZ36813.1 - 0.033 14.5 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HHH_8 PF14716.6 KEZ36813.1 - 0.11 12.8 0.0 0.86 10.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Fer4_15 PF13459.6 KEZ36814.1 - 2.7e-15 56.8 0.6 3.2e-15 56.6 0.6 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KEZ36814.1 - 1.9e-14 53.9 0.2 2.1e-14 53.8 0.2 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 KEZ36814.1 - 5.5e-10 39.2 0.0 5.9e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 KEZ36814.1 - 0.01 15.6 0.5 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KEZ36814.1 - 0.012 15.6 1.2 0.34 11.1 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ36814.1 - 0.24 11.6 1.7 0.6 10.3 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DUF308 PF03729.13 KEZ36815.1 - 9.1e-24 83.6 36.0 1.3e-08 35.0 7.7 3.2 1 1 2 3 3 3 3 Short repeat of unknown function (DUF308) DUF2892 PF11127.8 KEZ36815.1 - 2.8 8.0 41.8 3.6 7.7 9.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Neurensin PF14927.6 KEZ36815.1 - 6.2 6.5 23.2 1.8 8.3 2.2 3.7 2 2 1 3 3 3 0 Neurensin PRA1 PF03208.19 KEZ36815.1 - 8.5 6.0 18.9 0.18 11.4 8.2 2.1 1 1 1 2 2 2 0 PRA1 family protein SRAP PF02586.14 KEZ36816.1 - 1.5e-63 214.3 0.0 1.8e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Peptidase_M50B PF13398.6 KEZ36817.1 - 6.9e-57 192.3 10.7 8.3e-57 192.1 10.7 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Acyltransferase PF01553.21 KEZ36818.1 - 6e-28 97.1 0.0 7.6e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 KEZ36818.1 - 0.00069 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase FA_desaturase PF00487.24 KEZ36819.1 - 4.2e-27 95.6 11.6 4.2e-27 95.6 11.6 2.9 2 1 1 3 3 3 1 Fatty acid desaturase CPBP PF02517.16 KEZ36819.1 - 0.25 11.8 6.5 0.71 10.3 2.3 2.4 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease CrgA PF06781.12 KEZ36820.1 - 4.3e-05 23.5 0.0 4.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Cell division protein CrgA Mem_trans PF03547.18 KEZ36821.1 - 2.5e-18 65.7 22.1 3.1e-10 39.0 8.9 2.0 1 1 0 2 2 2 2 Membrane transport protein ELYS-bb PF16687.5 KEZ36822.1 - 0.029 13.0 0.0 0.094 11.3 0.0 1.7 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin PAC2 PF09754.9 KEZ36823.1 - 4.5e-46 157.5 0.0 5.6e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 PAC2 family DUF2269 PF10027.9 KEZ36824.1 - 0.35 10.9 14.7 0.53 10.3 14.7 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) MFS_1 PF07690.16 KEZ36825.1 - 3.3e-49 167.7 45.6 3.3e-49 167.7 45.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ36825.1 - 0.00039 19.4 7.9 0.00039 19.4 7.9 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TetR_C_1 PF02909.17 KEZ36826.1 - 5.9e-20 71.6 0.0 8.3e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ36826.1 - 2.1e-06 27.4 0.0 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family CN_hydrolase PF00795.22 KEZ36827.1 - 1.2e-53 182.1 0.0 1.7e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Putative_PNPOx PF01243.20 KEZ36827.1 - 2.1e-08 34.2 0.0 6.1e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Lipase_GDSL_2 PF13472.6 KEZ36827.1 - 0.0056 17.1 0.1 0.051 14.0 0.0 2.5 3 1 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family DUF364 PF04016.12 KEZ36827.1 - 0.064 12.8 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative heavy-metal chelation Lactamase_B PF00753.27 KEZ36828.1 - 1.1e-19 71.3 4.7 1.3e-19 70.9 4.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ36828.1 - 0.00087 18.8 0.2 0.0011 18.5 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Esterase_phd PF10503.9 KEZ36829.1 - 1.3e-08 34.7 0.6 3.1e-08 33.4 0.6 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ36829.1 - 2.9e-05 23.6 0.1 0.01 15.3 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ36829.1 - 0.012 15.3 0.3 0.067 12.8 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ36829.1 - 0.023 13.9 0.2 0.085 12.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 KEZ36830.1 - 5.9e-48 163.5 2.2 7.5e-48 163.1 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ36830.1 - 5.5e-45 153.2 0.3 6.7e-45 152.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ36830.1 - 4.8e-13 49.4 0.4 7.4e-13 48.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ36830.1 - 0.0011 18.5 0.2 0.0016 18.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ36830.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KEZ36830.1 - 0.094 11.8 0.4 0.16 11.0 0.4 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEZ36830.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Metallothio_Pro PF02069.16 KEZ36831.1 - 0.021 15.0 7.6 0.021 15.0 7.6 1.9 2 1 0 2 2 2 0 Prokaryotic metallothionein DUF1272 PF06906.11 KEZ36831.1 - 1.2 9.3 12.2 0.07 13.2 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) HTH_32 PF13565.6 KEZ36832.1 - 3e-16 59.8 3.5 2.5e-15 56.9 0.3 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KEZ36832.1 - 6e-15 55.0 0.1 1.3e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KEZ36832.1 - 3.6e-11 43.0 1.5 1.1e-10 41.5 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ36832.1 - 0.00015 21.4 0.0 0.00052 19.7 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KEZ36832.1 - 0.06 12.8 2.0 0.14 11.6 2.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Gpr1_Fun34_YaaH PF01184.19 KEZ36834.1 - 2.9e-14 53.2 13.9 3.7e-14 52.8 13.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 7TMR-DISM_7TM PF07695.11 KEZ36834.1 - 0.03 14.2 18.5 0.043 13.7 18.5 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Cyt_bd_oxida_II PF02322.15 KEZ36834.1 - 0.24 10.7 22.4 0.31 10.4 22.4 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DDE_Tnp_1_assoc PF13808.6 KEZ36835.1 - 1.3e-13 50.8 0.1 4.5e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ36835.1 - 0.00055 19.6 0.0 0.00085 19.0 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain His_Phos_1 PF00300.22 KEZ36836.1 - 2.4e-52 177.4 0.3 2.8e-52 177.2 0.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4774 PF15999.5 KEZ36836.1 - 0.045 13.6 0.3 0.089 12.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) RsfS PF02410.15 KEZ36837.1 - 9.5e-22 77.3 0.1 1.3e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Spore_YtfJ PF09579.10 KEZ36837.1 - 0.8 9.9 3.6 1.4 9.1 3.6 1.3 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) CTP_transf_like PF01467.26 KEZ36838.1 - 1.2e-29 103.4 0.0 1.4e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 KEZ36838.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase PGM_PMM_I PF02878.16 KEZ36839.1 - 2.5e-32 111.5 0.0 6.1e-32 110.2 0.0 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KEZ36839.1 - 4e-26 91.4 0.0 7.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEZ36839.1 - 5.7e-15 55.8 0.3 2.6e-13 50.5 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KEZ36839.1 - 8.1e-07 29.1 0.0 2.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain VWA_CoxE PF05762.14 KEZ36840.1 - 8e-45 152.9 0.2 2.3e-44 151.4 0.2 1.8 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein DinB_2 PF12867.7 KEZ36840.1 - 0.67 10.5 5.9 0.28 11.7 0.3 2.9 3 0 0 3 3 3 0 DinB superfamily AAA_5 PF07728.14 KEZ36841.1 - 6.4e-12 45.7 0.2 7.4e-11 42.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KEZ36841.1 - 4e-11 43.5 0.0 7.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ36841.1 - 8.6e-08 32.7 2.9 1.5e-06 28.7 2.9 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KEZ36841.1 - 2.9e-07 30.8 0.0 5e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 KEZ36841.1 - 4.3e-07 29.9 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KEZ36841.1 - 2e-05 23.7 0.0 3.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KEZ36841.1 - 7.1e-05 23.1 0.0 0.0002 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEZ36841.1 - 0.00015 21.6 0.1 0.23 11.2 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEZ36841.1 - 0.0026 18.3 0.0 0.0082 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ36841.1 - 0.0076 16.0 1.5 0.084 12.6 1.5 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ36841.1 - 0.008 16.1 1.7 0.032 14.1 0.1 2.4 2 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 KEZ36841.1 - 0.014 15.1 0.1 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KEZ36841.1 - 0.014 15.1 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 KEZ36841.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEZ36841.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KEZ36841.1 - 0.025 14.4 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 KEZ36841.1 - 0.035 14.5 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KEZ36841.1 - 0.043 14.2 2.4 4.7 7.5 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 KEZ36841.1 - 0.043 13.8 0.0 1.5 8.8 0.0 2.9 2 1 0 3 3 3 0 AAA domain IPT PF01745.16 KEZ36841.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Rad17 PF03215.15 KEZ36841.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KEZ36841.1 - 0.13 12.4 0.0 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KEZ36841.1 - 0.13 12.1 0.0 0.63 9.9 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 KEZ36841.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase dNK PF01712.19 KEZ36841.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Malate_synthase PF01274.22 KEZ36842.1 - 1e-186 621.3 0.0 1.2e-186 621.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase S4 PF01479.25 KEZ36842.1 - 0.012 15.4 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 S4 domain HpcH_HpaI PF03328.14 KEZ36842.1 - 0.014 14.5 0.0 0.13 11.4 0.0 2.4 2 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Aldedh PF00171.22 KEZ36843.1 - 2e-19 69.5 6.1 8.1e-17 60.9 5.2 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Metallophos PF00149.28 KEZ36844.1 - 2.5e-06 28.1 0.2 3.9e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SbcD_C PF12320.8 KEZ36844.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain Metallophos_2 PF12850.7 KEZ36844.1 - 0.0041 17.3 0.6 0.035 14.3 0.2 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain AAA_23 PF13476.6 KEZ36845.1 - 2e-17 64.4 0.0 3.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KEZ36845.1 - 2.8e-12 46.7 0.2 2.8e-12 46.7 0.2 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KEZ36845.1 - 6.1e-05 22.7 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KEZ36845.1 - 0.0015 18.4 0.0 0.014 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ36845.1 - 0.039 13.4 0.0 4.6 6.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ36845.1 - 0.2 11.9 5.9 0.33 11.2 1.1 3.0 3 0 0 3 3 3 0 AAA domain AA_kinase PF00696.28 KEZ36847.1 - 2.6e-36 125.4 5.9 3.3e-36 125.1 5.9 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KEZ36847.1 - 2.6e-18 65.8 0.1 8.3e-18 64.1 0.1 2.0 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 KEZ36847.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain Nic96 PF04097.14 KEZ36847.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 GTP1_OBG PF01018.22 KEZ36848.1 - 2e-51 173.6 2.6 2e-51 173.6 2.6 2.2 2 0 0 2 2 2 1 GTP1/OBG DUF1967 PF09269.11 KEZ36848.1 - 1.6e-22 79.2 0.0 2.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) MMR_HSR1 PF01926.23 KEZ36848.1 - 5.7e-22 77.9 0.0 9.5e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ36848.1 - 1.8e-07 30.8 0.0 3.7e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEZ36848.1 - 0.0015 18.5 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 KEZ36848.1 - 0.0077 15.7 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ribosomal_L27 PF01016.19 KEZ36849.1 - 8.5e-37 125.0 2.3 9.4e-37 124.9 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 KEZ36850.1 - 3.2e-31 107.6 0.3 3.6e-31 107.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrC_HhH_N PF08459.11 KEZ36850.1 - 0.028 14.3 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Polyoma_coat2 PF00761.20 KEZ36850.1 - 0.081 12.6 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein RNase_E_G PF10150.9 KEZ36852.1 - 1.2e-108 362.6 0.1 1.6e-108 362.3 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family DUF2344 PF10105.9 KEZ36853.1 - 1.1e-48 165.4 0.0 1.3e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Radical_SAM PF04055.21 KEZ36854.1 - 1.3e-15 58.2 0.0 2.8e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily FTSW_RODA_SPOVE PF01098.19 KEZ36855.1 - 7e-98 327.9 15.6 8e-98 327.7 15.6 1.0 1 0 0 1 1 1 1 Cell cycle protein MerC PF03203.14 KEZ36855.1 - 0.023 15.1 11.1 0.22 12.0 3.0 2.9 2 0 0 2 2 2 0 MerC mercury resistance protein Cytochrom_B561 PF03188.16 KEZ36855.1 - 0.099 12.8 4.7 0.69 10.0 2.0 2.9 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 Transpeptidase PF00905.22 KEZ36856.1 - 1.5e-69 234.6 0.0 1.9e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 KEZ36856.1 - 4.5e-40 137.9 0.0 1.6e-39 136.1 0.0 1.9 2 0 0 2 2 2 1 Penicillin-binding Protein dimerisation domain MreD PF04093.12 KEZ36857.1 - 5.4e-06 26.6 14.4 3.1e-05 24.1 14.4 2.0 1 1 0 1 1 1 1 rod shape-determining protein MreD ECF-ribofla_trS PF07155.12 KEZ36857.1 - 0.00016 21.7 13.8 0.0002 21.4 13.8 1.1 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component Thia_YuaJ PF09515.10 KEZ36857.1 - 0.29 11.1 9.1 0.19 11.8 7.3 1.5 1 1 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) ECF_trnsprt PF12822.7 KEZ36857.1 - 6.9 6.7 17.3 14 5.8 17.3 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component MreC PF04085.14 KEZ36858.1 - 7.8e-28 97.3 2.0 1.1e-27 96.8 2.0 1.2 1 0 0 1 1 1 1 rod shape-determining protein MreC Invasin_D3 PF09134.10 KEZ36858.1 - 0.061 13.6 0.2 0.061 13.6 0.2 2.5 3 0 0 3 3 3 0 Invasin, domain 3 YajC PF02699.15 KEZ36858.1 - 0.34 10.8 3.2 0.94 9.4 0.4 2.7 2 1 0 2 2 2 0 Preprotein translocase subunit MlaD PF02470.20 KEZ36858.1 - 1.1 9.6 3.6 11 6.4 0.2 2.5 1 1 0 2 2 2 0 MlaD protein MreB_Mbl PF06723.13 KEZ36859.1 - 1e-152 507.7 7.3 1.2e-152 507.5 7.3 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 KEZ36859.1 - 1.9e-11 42.9 1.2 2.4e-11 42.6 0.3 1.8 1 1 0 2 2 2 1 Hsp70 protein Actin PF00022.19 KEZ36859.1 - 5.8e-10 38.3 0.0 0.00065 18.4 0.0 2.2 2 0 0 2 2 2 2 Actin FtsA PF14450.6 KEZ36859.1 - 4.6e-09 36.6 1.7 1.2e-08 35.3 0.2 2.1 2 0 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 KEZ36859.1 - 0.00017 20.8 0.1 0.0036 16.4 0.0 2.3 3 0 0 3 3 3 1 Type IV pilus assembly protein PilM; DDR PF08841.10 KEZ36859.1 - 0.0017 17.4 1.2 0.0035 16.4 1.2 1.5 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain NDK PF00334.19 KEZ36860.1 - 2.7e-51 173.1 0.0 3.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Mur_ligase_M PF08245.12 KEZ36861.1 - 0.00012 22.2 0.0 0.0021 18.1 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEZ36861.1 - 0.022 15.0 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KEZ36862.1 - 9.4e-16 58.4 0.0 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEZ36862.1 - 4.2e-07 30.1 0.0 1.6e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain AAA_2 PF07724.14 KEZ36863.1 - 2.4e-49 167.7 0.0 3.6e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 KEZ36863.1 - 1e-20 73.3 6.0 1.9e-20 72.4 6.0 1.5 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 KEZ36863.1 - 7.3e-18 65.3 0.0 1.9e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KEZ36863.1 - 8e-16 57.9 0.4 2.4e-15 56.4 0.4 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KEZ36863.1 - 7.5e-08 32.5 0.0 1.3e-06 28.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KEZ36863.1 - 1.2e-05 24.8 0.9 0.0025 17.2 0.2 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KEZ36863.1 - 1.5e-05 24.8 0.6 0.00014 21.6 0.3 2.5 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ36863.1 - 1.7e-05 25.1 0.4 0.00017 21.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain MCM PF00493.23 KEZ36863.1 - 0.00033 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 KEZ36863.1 - 0.00065 19.4 0.0 0.073 12.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KEZ36863.1 - 0.0011 19.4 0.2 0.012 16.0 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KEZ36863.1 - 0.002 18.7 0.0 0.0045 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEZ36863.1 - 0.0027 17.7 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ36863.1 - 0.0048 16.7 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KEZ36863.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KEZ36863.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KEZ36863.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KEZ36863.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KEZ36863.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 KEZ36863.1 - 0.024 14.8 0.0 0.061 13.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KEZ36863.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 KEZ36863.1 - 0.037 13.1 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 KEZ36863.1 - 0.037 13.2 0.2 0.074 12.2 0.2 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 KEZ36863.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEZ36863.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 KEZ36863.1 - 0.089 12.1 0.9 1.7 7.9 0.1 2.3 1 1 0 2 2 2 0 KaiC PhoH PF02562.16 KEZ36863.1 - 0.098 12.1 0.1 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 KEZ36863.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KEZ36863.1 - 0.12 12.5 0.0 0.48 10.5 0.0 2.1 3 0 0 3 3 1 0 Shikimate kinase AAA_3 PF07726.11 KEZ36863.1 - 0.12 12.2 0.3 0.79 9.6 0.0 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEZ36863.1 - 0.13 11.8 1.2 0.95 9.0 0.2 2.2 1 1 0 2 2 2 0 AAA domain CLP_protease PF00574.23 KEZ36864.1 - 5.9e-69 231.6 0.1 6.7e-69 231.4 0.1 1.0 1 0 0 1 1 1 1 Clp protease CLP_protease PF00574.23 KEZ36865.1 - 2.7e-59 200.1 0.0 4.7e-59 199.3 0.0 1.3 2 0 0 2 2 2 1 Clp protease CLP_protease PF00574.23 KEZ36866.1 - 2.3e-76 255.8 0.0 2.8e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Clp protease GTP1_OBG PF01018.22 KEZ36866.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 GTP1/OBG Trigger_N PF05697.13 KEZ36867.1 - 7e-41 139.9 0.6 2e-40 138.4 0.6 1.8 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 KEZ36867.1 - 1.5e-28 99.9 1.5 1.5e-28 99.9 1.5 2.3 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 KEZ36867.1 - 6.3e-06 26.4 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ACT_6 PF13740.6 KEZ36867.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.9 1 0 0 1 1 1 1 ACT domain Phage_integrase PF00589.22 KEZ36868.1 - 2.2e-13 50.4 0.0 3.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ36868.1 - 1.7e-07 31.4 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 KEZ36868.1 - 0.0074 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain HTH_17 PF12728.7 KEZ36869.1 - 5.1e-10 39.4 0.1 5.5e-10 39.3 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain DUF746 PF05344.11 KEZ36869.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) AsmA_2 PF13502.6 KEZ36870.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 AsmA-like C-terminal region HTH_OrfB_IS605 PF12323.8 KEZ36871.1 - 1.1e-12 47.2 0.4 4.5e-12 45.3 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 KEZ36871.1 - 6.6e-10 39.3 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Probable transposase Resolvase PF00239.21 KEZ36872.1 - 2.1e-17 63.6 0.3 3.1e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain OB_Dis3 PF17849.1 KEZ36872.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) DNA_pol_lambd_f PF10391.9 KEZ36872.1 - 0.029 14.2 0.1 0.062 13.1 0.1 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Exc PF07825.11 KEZ36872.1 - 0.034 14.1 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 Excisionase-like protein HTH_23 PF13384.6 KEZ36872.1 - 0.057 13.2 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Imm21 PF15589.6 KEZ36872.1 - 0.063 13.3 0.2 0.85 9.7 0.1 2.1 1 1 1 2 2 2 0 Immunity protein 21 MerR PF00376.23 KEZ36872.1 - 0.11 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein Rft-1 PF04506.13 KEZ36873.1 - 0.031 13.0 0.0 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 Rft protein TerB PF05099.13 KEZ36874.1 - 1.4e-16 60.7 4.8 1.9e-16 60.3 4.8 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TerB NUDIX PF00293.28 KEZ36874.1 - 0.034 14.2 0.2 0.073 13.1 0.0 1.7 2 0 0 2 2 2 0 NUDIX domain SCP2 PF02036.17 KEZ36875.1 - 1.8e-07 31.6 0.0 2.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KEZ36875.1 - 0.00034 20.9 0.0 0.00045 20.5 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Aminotran_4 PF01063.19 KEZ36876.1 - 2.6e-18 66.7 0.0 3.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV TIR_2 PF13676.6 KEZ36878.1 - 4.3e-21 75.7 0.0 1e-20 74.5 0.0 1.7 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 KEZ36878.1 - 2.3e-05 24.2 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain Na_H_Exchanger PF00999.21 KEZ36879.1 - 3.4e-46 157.8 45.7 4.3e-46 157.4 45.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ldh_1_C PF02866.18 KEZ36880.1 - 4.9e-31 107.9 0.0 7.4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEZ36880.1 - 1.3e-29 103.1 0.0 1.9e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Peripla_BP_6 PF13458.6 KEZ36881.1 - 8.5e-70 236.1 7.7 1e-69 235.8 7.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KEZ36881.1 - 4.1e-06 26.0 0.0 1.1e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain Haem_degrading PF03928.14 KEZ36882.1 - 1.3e-25 89.8 4.8 2.3e-25 89.0 4.8 1.4 1 1 0 1 1 1 1 Haem-degrading Diacid_rec PF05651.13 KEZ36882.1 - 0.1 12.3 0.4 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative sugar diacid recognition DUF397 PF04149.12 KEZ36884.1 - 1.9e-18 66.3 0.0 2.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KEZ36886.1 - 1.2e-12 48.0 0.6 5.2e-12 45.9 0.4 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ36886.1 - 0.0018 18.2 0.1 0.0036 17.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 KEZ36886.1 - 0.0067 16.2 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HTH_25 PF13413.6 KEZ36886.1 - 0.043 13.7 0.4 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 KEZ36886.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HATPase_c_2 PF13581.6 KEZ36887.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Adhesin_P1_N PF18652.1 KEZ36887.1 - 5.3 7.1 5.4 13 5.9 0.5 2.9 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain DUF3418 PF11898.8 KEZ36888.1 - 3e-230 765.9 0.6 4.1e-230 765.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 KEZ36888.1 - 2.7e-17 62.9 0.0 5.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEZ36888.1 - 3.5e-17 62.7 0.0 8.3e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEZ36888.1 - 1.9e-10 41.0 0.0 4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ36888.1 - 1.5e-06 28.1 0.1 2.8e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KEZ36888.1 - 1.9e-05 25.0 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEZ36888.1 - 0.00026 20.1 0.0 0.00061 18.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KEZ36888.1 - 0.00076 19.8 0.1 0.0032 17.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ36888.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KEZ36888.1 - 0.0062 16.3 0.1 0.022 14.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KEZ36888.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KEZ36888.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KEZ36888.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ36888.1 - 0.18 12.3 0.0 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter TPR_12 PF13424.6 KEZ36889.1 - 1e-92 304.5 66.3 1.5e-13 50.8 2.0 9.9 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ36889.1 - 7.1e-85 276.9 48.7 2.7e-09 36.6 0.0 11.7 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ36889.1 - 4.1e-29 98.4 23.1 0.0042 17.0 0.0 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TIR_2 PF13676.6 KEZ36889.1 - 7.9e-20 71.6 0.0 1.8e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 TIR domain TPR_2 PF07719.17 KEZ36889.1 - 1.4e-16 59.2 15.5 0.3 11.3 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ36889.1 - 1.5e-15 57.4 24.6 0.00024 21.6 0.0 8.5 7 1 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ36889.1 - 6e-15 54.7 67.2 0.0069 17.1 1.2 13.2 7 2 6 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ36889.1 - 7.3e-13 47.7 0.0 0.39 10.6 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ36889.1 - 2.1e-09 36.9 0.0 1.4 9.3 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ36889.1 - 3.8e-08 33.8 76.6 0.00014 22.5 3.6 10.4 7 4 3 10 10 8 5 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ36889.1 - 2.2e-06 28.1 0.8 2.2e-06 28.1 0.8 3.8 3 1 0 3 3 3 1 AAA ATPase domain TPR_20 PF14561.6 KEZ36889.1 - 9.3e-06 25.9 16.9 1.1 9.6 0.1 8.0 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ36889.1 - 3e-05 24.1 0.3 8.4 7.0 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ36889.1 - 6.1e-05 23.3 98.3 0.011 16.2 0.3 13.6 15 0 0 15 15 10 6 Tetratricopeptide repeat TPR_5 PF12688.7 KEZ36889.1 - 0.00026 21.2 15.1 0.54 10.5 0.7 5.5 6 0 0 6 6 5 2 Tetratrico peptide repeat TPR_6 PF13174.6 KEZ36889.1 - 0.00048 20.6 21.8 2.5 8.9 0.1 8.8 11 0 0 11 11 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ36889.1 - 0.0016 18.6 0.1 2.1 8.7 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 KEZ36889.1 - 0.011 14.9 0.0 0.042 13.0 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KEZ36889.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KEZ36889.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ36889.1 - 0.095 12.6 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KEZ36889.1 - 0.28 11.2 0.0 0.45 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain BAR PF03114.18 KEZ36890.1 - 0.025 14.2 0.3 0.033 13.8 0.3 1.1 1 0 0 1 1 1 0 BAR domain DUF3878 PF12994.7 KEZ36890.1 - 0.21 11.0 0.1 0.27 10.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) GalKase_gal_bdg PF10509.9 KEZ36891.1 - 8.3e-21 73.3 0.2 2.9e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KEZ36891.1 - 4.2e-11 42.9 5.2 4.2e-11 42.9 5.2 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEZ36891.1 - 1.7e-08 34.7 0.7 4.9e-08 33.2 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GalP_UDP_transf PF01087.22 KEZ36892.1 - 7e-48 163.5 0.0 1e-47 163.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KEZ36892.1 - 6.1e-43 146.4 0.0 1.5e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KEZ36892.1 - 0.084 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) Phage_TAC_6 PF09550.10 KEZ36892.1 - 0.26 11.8 6.5 11 6.5 0.1 3.4 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC MerR-DNA-bind PF09278.11 KEZ36893.1 - 2.5e-18 66.3 0.2 4.7e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 KEZ36893.1 - 4.9e-16 58.6 0.0 6.5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ36893.1 - 6.3e-13 48.2 0.3 1.2e-12 47.3 0.3 1.5 1 0 0 1 1 1 1 MerR family regulatory protein TPR_MLP1_2 PF07926.12 KEZ36893.1 - 0.26 11.4 0.0 0.34 11.0 0.0 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FMN_red PF03358.15 KEZ36894.1 - 2.4e-23 82.6 0.1 3.1e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEZ36894.1 - 8.5e-05 22.3 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Peripla_BP_6 PF13458.6 KEZ36895.1 - 5.4e-33 115.1 4.9 7.3e-33 114.7 4.9 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KEZ36895.1 - 0.00015 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 KEZ36895.1 - 0.00055 19.1 0.0 0.00089 18.4 0.0 1.4 1 1 0 1 1 1 1 Receptor family ligand binding region ABC_tran PF00005.27 KEZ36896.1 - 6.5e-48 162.7 0.0 5.9e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter BPD_transp_2 PF02653.16 KEZ36896.1 - 8.6e-42 143.1 99.1 1.7e-21 76.6 39.3 3.5 2 1 1 3 3 3 2 Branched-chain amino acid transport system / permease component AAA_21 PF13304.6 KEZ36896.1 - 2e-14 54.1 12.4 0.0015 18.4 0.2 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 KEZ36896.1 - 4.3e-08 32.9 0.7 1.3e-07 31.4 0.1 2.2 2 0 0 2 2 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 KEZ36896.1 - 5.4e-08 33.6 0.2 0.0014 19.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ36896.1 - 1.9e-07 30.7 0.1 0.0016 18.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KEZ36896.1 - 3.9e-06 26.5 0.6 0.047 13.1 0.0 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEZ36896.1 - 3.8e-05 23.5 11.7 0.00033 20.4 1.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEZ36896.1 - 6.4e-05 23.4 5.1 0.039 14.3 1.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_27 PF13514.6 KEZ36896.1 - 7.1e-05 22.5 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KEZ36896.1 - 0.00014 22.3 0.0 1.3 9.4 0.0 3.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KEZ36896.1 - 0.00088 19.2 0.5 0.66 9.9 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KEZ36896.1 - 0.0025 18.0 0.0 1.8 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KEZ36896.1 - 0.0035 17.0 6.6 0.043 13.5 0.9 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KEZ36896.1 - 0.0039 16.8 2.9 0.038 13.5 1.7 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KEZ36896.1 - 0.0045 16.8 0.0 2.1 8.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KEZ36896.1 - 0.0073 16.5 0.0 8.6 6.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KEZ36896.1 - 0.012 15.9 3.3 1.9 8.7 0.1 3.5 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KEZ36896.1 - 0.018 15.4 1.3 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEZ36896.1 - 0.035 14.1 1.3 7 6.7 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KEZ36896.1 - 0.045 13.7 0.3 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KEZ36896.1 - 0.053 13.4 0.1 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 NTPase MukB PF04310.12 KEZ36896.1 - 0.098 12.4 2.7 0.65 9.8 0.3 2.2 2 0 0 2 2 2 0 MukB N-terminal AAA_28 PF13521.6 KEZ36896.1 - 0.13 12.5 3.9 1.7 8.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEZ36896.1 - 0.15 11.8 0.8 4.5 7.0 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KEZ36896.1 - 0.15 12.1 0.9 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase KdpD PF02702.17 KEZ36896.1 - 0.18 11.3 0.2 7.1 6.0 0.1 2.6 2 1 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_24 PF13479.6 KEZ36896.1 - 0.19 11.5 1.7 8.8 6.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEZ36896.1 - 0.19 11.6 0.1 15 5.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KEZ36896.1 - 0.2 11.0 0.5 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KEZ36896.1 - 0.27 10.7 0.5 9.4 5.7 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KEZ36896.1 - 0.31 10.0 1.2 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KEZ36896.1 - 0.6 9.9 1.4 5.5 6.7 0.3 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KEZ36896.1 - 0.63 9.3 1.3 30 3.8 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KEZ36896.1 - 1.4 8.5 3.1 19 4.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 KEZ36896.1 - 4.7 6.6 5.0 15 5.0 0.1 2.8 3 0 0 3 3 3 0 PhoH-like protein CAP PF00188.26 KEZ36897.1 - 1.8e-21 77.2 0.0 2.7e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TerD PF02342.18 KEZ36897.1 - 6.7e-20 71.4 0.0 4e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 TerD domain Collagen PF01391.18 KEZ36897.1 - 0.01 15.5 19.6 0.036 13.8 19.6 2.0 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) CE2_N PF17996.1 KEZ36898.1 - 3.9e-07 30.0 0.0 0.0047 16.9 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Glyco_hydro_26 PF02156.15 KEZ36898.1 - 7.4e-06 25.6 2.4 1.3e-05 24.8 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 MBG PF17883.1 KEZ36898.1 - 0.23 12.1 4.9 0.63 10.7 1.6 2.8 2 1 0 2 2 2 0 MBG domain DUF1918 PF08940.11 KEZ36899.1 - 9.7e-20 70.0 0.1 1.2e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) PIG-L PF02585.17 KEZ36900.1 - 5.6e-25 88.5 0.1 8.5e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase baeRF_family2 PF18844.1 KEZ36900.1 - 0.0043 17.1 0.1 0.75 9.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial archaeo-eukaryotic release factor family 2 PALP PF00291.25 KEZ36901.1 - 8.9e-48 163.2 0.0 1e-47 163.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VWA_CoxE PF05762.14 KEZ36901.1 - 0.11 11.9 0.2 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Response_reg PF00072.24 KEZ36902.1 - 4.3e-19 68.7 0.0 5e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Amidohydro_1 PF01979.20 KEZ36903.1 - 9.9e-13 48.1 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ36903.1 - 4.1e-06 26.5 14.4 9.7e-05 22.0 7.7 2.4 1 1 1 2 2 2 2 Amidohydrolase family Mur_ligase PF01225.25 KEZ36903.1 - 0.027 14.8 0.4 10 6.5 0.0 2.6 2 0 0 2 2 2 0 Mur ligase family, catalytic domain ADH_zinc_N PF00107.26 KEZ36903.1 - 0.2 11.6 0.9 0.35 10.9 0.9 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LysR_substrate PF03466.20 KEZ36905.1 - 1.6e-42 145.2 6.8 2.6e-42 144.6 6.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 KEZ36905.1 - 4.7e-25 87.3 0.9 4.7e-25 87.3 0.9 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like_2 PF12849.7 KEZ36905.1 - 0.065 12.9 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 PBP superfamily domain SBP_bac_11 PF13531.6 KEZ36905.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein VWA_3_C PF18571.1 KEZ36905.1 - 0.24 11.3 2.6 0.23 11.3 0.8 1.9 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Sdh_cyt PF01127.22 KEZ36906.1 - 2.2e-06 27.7 16.6 1e-05 25.5 6.0 2.3 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF5538 PF17692.1 KEZ36906.1 - 0.063 13.3 0.4 0.25 11.4 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5538) 7tm_1 PF00001.21 KEZ36906.1 - 0.14 11.5 1.7 0.13 11.6 0.5 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF2189 PF09955.9 KEZ36906.1 - 4 7.7 10.0 0.69 10.2 1.4 2.8 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) FAD_binding_2 PF00890.24 KEZ36907.1 - 8.2e-56 189.9 0.5 1.2e-55 189.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KEZ36907.1 - 1e-33 116.1 0.0 2.5e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 KEZ36907.1 - 5.4e-06 26.2 4.8 1.3e-05 25.0 2.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ36907.1 - 9.8e-05 21.7 1.8 0.002 17.4 1.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ36907.1 - 0.00076 18.7 2.0 0.076 12.1 1.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 KEZ36907.1 - 0.0021 16.9 0.1 0.78 8.4 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KEZ36907.1 - 0.027 14.7 0.2 0.1 12.8 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain YjeF_N PF03853.15 KEZ36907.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Fer2_3 PF13085.6 KEZ36908.1 - 5.7e-23 81.0 0.4 6.8e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 KEZ36908.1 - 1.5e-07 31.8 0.7 1.5e-07 31.8 0.7 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KEZ36908.1 - 1.7e-06 27.6 3.7 1.7e-06 27.6 3.7 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ36908.1 - 2e-06 28.3 1.9 2e-06 28.3 1.9 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ36908.1 - 5.9e-06 26.1 2.2 5.9e-06 26.1 2.2 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_9 PF13187.6 KEZ36908.1 - 1.9e-05 24.8 15.3 0.00022 21.3 1.9 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ36908.1 - 4.4e-05 23.9 0.4 4.4e-05 23.9 0.4 1.8 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEZ36908.1 - 7.5e-05 22.9 1.2 7.5e-05 22.9 1.2 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ36908.1 - 0.0001 22.2 3.9 0.0001 22.2 3.9 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KEZ36908.1 - 0.00014 21.9 4.4 0.00014 21.9 4.4 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KEZ36908.1 - 0.00028 21.0 0.3 0.00028 21.0 0.3 2.0 3 0 0 3 3 1 1 4Fe-4S dicluster domain Fer2 PF00111.27 KEZ36908.1 - 0.00057 19.8 0.1 0.00057 19.8 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.6 KEZ36908.1 - 0.0013 19.4 0.1 0.004 17.9 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KEZ36908.1 - 0.0024 18.4 2.7 0.0071 16.9 2.7 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KEZ36908.1 - 0.0034 18.2 6.3 0.0034 18.2 6.3 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_18 PF13746.6 KEZ36908.1 - 0.015 15.5 2.7 0.77 10.0 1.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ36908.1 - 0.021 15.7 2.1 0.021 15.7 2.1 2.0 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 KEZ36908.1 - 0.021 15.6 0.6 0.021 15.6 0.6 2.2 3 0 0 3 3 2 0 4Fe-4S dicluster domain TF_Zn_Ribbon PF08271.12 KEZ36908.1 - 4.4 6.9 7.1 1.4 8.5 0.3 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding DDE_Tnp_1_6 PF13751.6 KEZ36909.1 - 2.6e-08 34.1 1.6 3.3e-08 33.8 1.6 1.1 1 0 0 1 1 1 1 Transposase DDE domain PEP_mutase PF13714.6 KEZ36910.1 - 3.4e-16 59.4 0.0 4.2e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pantoate_transf PF02548.15 KEZ36910.1 - 0.0003 20.2 0.1 0.00038 19.9 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KEZ36911.1 - 9.6e-13 48.1 0.1 1.1e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DDE_Tnp_4 PF13359.6 KEZ36912.1 - 0.00083 19.0 0.0 0.00086 19.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DAO PF01266.24 KEZ36913.1 - 1.5e-53 182.6 8.0 1.8e-53 182.3 8.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ36913.1 - 3.4e-07 30.4 0.1 8.9e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ36913.1 - 4.8e-05 22.7 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ36913.1 - 0.00024 21.6 0.1 0.00049 20.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ36913.1 - 0.00067 18.5 0.0 0.017 13.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KEZ36913.1 - 0.00084 18.5 0.4 0.0022 17.2 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ36913.1 - 0.0055 16.0 0.0 0.0088 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEZ36913.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KEZ36913.1 - 0.015 15.3 0.2 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 KEZ36913.1 - 0.018 14.7 0.2 0.031 13.9 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KEZ36913.1 - 0.02 15.2 0.1 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KEZ36913.1 - 0.041 13.8 0.1 0.062 13.2 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEZ36913.1 - 0.061 12.9 0.1 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KEZ36913.1 - 0.18 11.7 2.2 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 KEZ36913.1 - 0.2 10.9 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF4012 PF13196.6 KEZ36914.1 - 6.1e-38 130.5 0.0 3.1e-37 128.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4012) Alpha_E1_glycop PF01589.16 KEZ36914.1 - 0.016 13.9 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein ParA PF10609.9 KEZ36915.1 - 5.7e-12 45.6 0.2 7.1e-11 42.0 0.2 2.1 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEZ36915.1 - 3.1e-08 33.8 0.0 1.7e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Wzz PF02706.15 KEZ36915.1 - 1.3e-05 25.4 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Chain length determinant protein AAA_31 PF13614.6 KEZ36915.1 - 4e-05 23.6 0.0 0.0056 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KEZ36915.1 - 8e-05 22.0 0.1 0.00044 19.6 0.0 2.1 3 0 0 3 3 3 1 ATPase MipZ GNVR PF13807.6 KEZ36915.1 - 0.00068 19.5 1.8 0.0033 17.3 0.0 2.6 3 0 0 3 3 3 1 G-rich domain on putative tyrosine kinase FTHFS PF01268.19 KEZ36915.1 - 0.022 13.0 0.1 0.032 12.4 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase APS_kinase PF01583.20 KEZ36915.1 - 0.038 13.9 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 KEZ36915.1 - 0.047 13.3 0.1 0.17 11.5 0.0 2.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 KEZ36915.1 - 0.058 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_26 PF13500.6 KEZ36915.1 - 0.08 12.8 0.2 4.8 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KEZ36915.1 - 0.1 12.3 0.1 9.8 5.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein LapA_dom PF06305.11 KEZ36915.1 - 1.3 8.9 4.0 1.5 8.7 0.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Polysacc_synt_2 PF02719.15 KEZ36916.1 - 2.8e-95 318.8 0.0 3.8e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEZ36916.1 - 8.4e-22 77.8 0.0 4.4e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ36916.1 - 4e-14 52.8 0.0 5.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEZ36916.1 - 3e-09 36.4 0.0 6.2e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEZ36916.1 - 6.8e-09 35.1 0.0 9.8e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_binding_3 PF13727.6 KEZ36916.1 - 0.0011 19.1 0.1 0.0031 17.5 0.0 1.9 1 1 0 1 1 1 1 CoA-binding domain KR PF08659.10 KEZ36916.1 - 0.0039 17.1 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KEZ36916.1 - 0.0043 16.5 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase ThiF PF00899.21 KEZ36916.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_10 PF13460.6 KEZ36916.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 KEZ36916.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein Colicin_V PF02674.16 KEZ36916.1 - 0.078 13.0 6.1 0.17 11.9 6.1 1.5 1 0 0 1 1 1 0 Colicin V production protein DnaJ_CXXCXGXG PF00684.19 KEZ36918.1 - 5.3e-05 23.5 5.6 8.5e-05 22.8 5.6 1.5 1 1 0 1 1 1 1 DnaJ central domain DUF1356 PF07092.12 KEZ36918.1 - 5.4e-05 22.6 3.9 0.034 13.4 0.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 KEZ36918.1 - 0.00063 19.6 6.2 0.054 13.5 0.7 2.3 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_9 PF14369.6 KEZ36918.1 - 0.0014 18.9 1.0 1.3 9.4 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon Mu-like_Com PF10122.9 KEZ36918.1 - 0.0024 17.3 2.2 0.06 12.8 0.3 2.3 2 0 0 2 2 2 1 Mu-like prophage protein Com Zn_Tnp_IS1 PF03811.13 KEZ36918.1 - 0.0041 16.8 0.6 1.3 8.8 0.1 2.2 2 0 0 2 2 2 2 InsA N-terminal domain Zn-ribbon_8 PF09723.10 KEZ36918.1 - 0.0056 16.8 1.4 1 9.6 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain Lar_restr_allev PF14354.6 KEZ36918.1 - 0.0069 16.7 3.2 0.96 9.9 0.1 2.8 3 0 0 3 3 3 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 KEZ36918.1 - 0.0074 16.2 0.4 3.8 7.6 0.0 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 KEZ36918.1 - 0.015 15.2 0.9 5.5 7.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KEZ36918.1 - 0.033 13.7 2.4 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-CSL PF05207.13 KEZ36918.1 - 0.035 13.8 0.1 0.046 13.4 0.1 1.2 1 0 0 1 1 1 0 CSL zinc finger zf-FPG_IleRS PF06827.14 KEZ36918.1 - 0.067 13.1 7.5 1.2 9.1 0.4 2.5 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS TRAF6_Z2 PF18048.1 KEZ36918.1 - 0.081 13.0 1.2 3.5 7.8 0.3 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 HypA PF01155.19 KEZ36918.1 - 0.087 12.9 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 KEZ36918.1 - 0.14 12.2 1.5 8.7 6.4 0.1 2.1 1 1 1 2 2 2 0 CpXC protein DUF5351 PF17302.2 KEZ36918.1 - 0.16 12.2 6.6 0.85 9.9 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5351) TFIIS_C PF01096.18 KEZ36918.1 - 0.18 11.7 2.1 5.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) YacG PF03884.14 KEZ36918.1 - 0.21 11.4 1.5 11 5.9 0.1 2.2 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf_UBZ PF18439.1 KEZ36918.1 - 0.26 10.9 2.6 11 5.7 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 KEZ36918.1 - 0.33 10.7 3.5 1 9.2 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-TFIIB PF13453.6 KEZ36918.1 - 0.71 9.2 7.4 4.3 6.7 7.4 2.0 1 1 0 1 1 1 0 Transcription factor zinc-finger zf_CopZ PF18423.1 KEZ36918.1 - 0.75 9.8 4.0 12 6.0 0.2 2.3 2 0 0 2 2 2 0 Zinc binding domain zf-ACC PF17848.1 KEZ36918.1 - 1.6 8.9 4.7 2.4 8.3 0.6 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Epimerase PF01370.21 KEZ36919.1 - 8.1e-45 153.2 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ36919.1 - 1.5e-38 133.1 0.0 1.8e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ36919.1 - 5.8e-15 55.0 0.0 7.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ36919.1 - 2.4e-10 40.0 0.1 2.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KEZ36919.1 - 8.9e-10 38.2 0.1 6.8e-08 32.0 0.4 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEZ36919.1 - 1.3e-07 31.1 0.1 1.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KEZ36919.1 - 1.9e-06 27.6 0.2 2.9e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ36919.1 - 1.9e-06 27.9 3.1 2.9e-06 27.3 3.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KEZ36919.1 - 0.0029 17.8 0.3 0.0052 17.0 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KEZ36919.1 - 0.0033 16.9 0.7 0.0033 16.9 0.7 2.0 3 0 0 3 3 3 1 short chain dehydrogenase Ldh_1_N PF00056.23 KEZ36919.1 - 0.2 11.7 0.4 0.35 11.0 0.4 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KEZ36919.1 - 0.69 9.8 3.5 2 8.3 3.5 1.9 1 1 0 1 1 1 0 KR domain Hexapep PF00132.24 KEZ36920.1 - 5.5e-14 51.2 11.4 8.9e-06 25.2 0.6 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) PglD_N PF17836.1 KEZ36920.1 - 1.9e-08 34.8 0.0 4.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 PglD N-terminal domain Hexapep_2 PF14602.6 KEZ36920.1 - 4.6e-07 29.5 8.2 6.3e-06 25.8 1.4 3.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Alg14 PF08660.11 KEZ36920.1 - 0.017 15.1 0.0 0.075 13.0 0.0 1.8 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Bactofilin PF04519.13 KEZ36920.1 - 0.29 11.4 4.6 1.2 9.5 4.6 1.9 1 1 0 1 1 1 0 Polymer-forming cytoskeletal Y_phosphatase3 PF13350.6 KEZ36921.1 - 7.1e-58 196.3 0.0 7.9e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KEZ36921.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEZ36921.1 - 0.0049 16.5 0.0 0.0062 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4171 PF13775.6 KEZ36921.1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) SLT PF01464.20 KEZ36922.1 - 2e-17 62.9 0.0 2.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 KEZ36922.1 - 1.8e-10 40.5 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Transglycosylas PF06737.14 KEZ36922.1 - 0.0058 17.2 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase-like domain S4_2 PF13275.6 KEZ36923.1 - 6.2e-25 86.8 0.3 6.8e-25 86.7 0.3 1.0 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 KEZ36923.1 - 0.00012 21.7 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 S4 domain ThiS PF02597.20 KEZ36923.1 - 0.013 16.2 0.0 0.016 15.9 0.0 1.2 1 0 0 1 1 1 0 ThiS family HTH_30 PF13556.6 KEZ36924.1 - 2.8e-18 65.5 1.6 6.3e-18 64.3 1.6 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 KEZ36924.1 - 2.1e-08 34.4 0.3 2.1e-08 34.4 0.3 2.2 2 1 0 2 2 2 1 GGDEF-like domain Trypan_PARP PF05887.11 KEZ36924.1 - 0.011 15.7 21.0 0.011 15.7 21.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Acyl_transf_1 PF00698.21 KEZ36925.1 - 4.1e-19 69.2 0.5 5.8e-19 68.7 0.5 1.1 1 0 0 1 1 1 1 Acyl transferase domain RraA-like PF03737.15 KEZ36925.1 - 0.096 12.8 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Aldolase/RraA ACP_syn_III_C PF08541.10 KEZ36926.1 - 5.8e-28 96.9 0.0 7.5e-27 93.3 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KEZ36926.1 - 3.2e-26 91.0 0.4 3.2e-26 91.0 0.4 2.7 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KEZ36926.1 - 5.9e-07 29.1 1.4 7.5e-07 28.8 0.6 1.5 1 1 0 1 1 1 1 Thiolase, N-terminal domain Chal_sti_synt_N PF00195.19 KEZ36926.1 - 0.0028 17.1 1.2 0.0052 16.2 1.2 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain PP-binding PF00550.25 KEZ36927.1 - 6.7e-16 58.4 0.3 7.5e-16 58.2 0.3 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KEZ36927.1 - 0.011 15.9 0.4 0.013 15.8 0.4 1.1 1 0 0 1 1 1 0 Acyl-carrier Ribosomal_L50 PF10501.9 KEZ36927.1 - 0.053 13.7 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S DEK_C PF08766.11 KEZ36927.1 - 0.084 12.8 0.2 0.45 10.5 0.1 2.1 1 1 2 3 3 3 0 DEK C terminal domain ketoacyl-synt PF00109.26 KEZ36928.1 - 3.2e-51 174.3 3.4 4.9e-51 173.7 3.4 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ36928.1 - 3.5e-31 107.7 1.7 7e-31 106.7 1.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KEZ36928.1 - 2.5e-06 27.1 1.0 5.7e-06 25.9 0.5 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF5546 PF17700.1 KEZ36928.1 - 0.072 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5546) FA_synthesis PF02504.15 KEZ36928.1 - 0.17 10.9 1.4 0.27 10.3 1.2 1.4 1 1 0 1 1 1 0 Fatty acid synthesis protein ACP_syn_III PF08545.10 KEZ36928.1 - 2.2 8.2 6.8 20 5.1 0.8 3.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Carboxyl_trans PF01039.22 KEZ36929.1 - 6.5e-124 414.3 1.7 8e-124 414.0 1.7 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KEZ36929.1 - 0.0016 18.0 0.9 0.0016 18.0 0.9 2.6 2 1 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) MFS_3 PF05977.13 KEZ36930.1 - 1.5e-63 215.0 38.5 1.9e-63 214.7 38.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KEZ36930.1 - 6.5e-35 120.7 65.0 6.8e-26 91.0 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ36930.1 - 4.2 6.1 16.4 0.4 9.5 4.5 2.3 2 0 0 2 2 2 0 MFS_1 like family AAA PF00004.29 KEZ36931.1 - 1.9e-23 83.3 0.0 3e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KEZ36931.1 - 1.4e-19 70.7 1.1 2.5e-19 69.9 1.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_22 PF13401.6 KEZ36931.1 - 0.0042 17.4 0.0 0.059 13.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEZ36931.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ36931.1 - 0.014 15.8 0.1 0.053 13.9 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_lid_3 PF17862.1 KEZ36931.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain Mg_chelatase PF01078.21 KEZ36931.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KEZ36931.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KEZ36931.1 - 0.048 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IPT PF01745.16 KEZ36931.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase AAA_33 PF13671.6 KEZ36931.1 - 0.084 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ36931.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KEZ36931.1 - 0.2 11.4 0.1 0.43 10.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2157 PF09925.9 KEZ36931.1 - 0.45 10.3 6.5 0.061 13.1 0.5 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) TetR_C_15 PF17918.1 KEZ36931.1 - 0.9 10.3 3.3 17 6.2 0.0 3.3 4 0 0 4 4 3 0 Tetracyclin repressor-like, C-terminal domain NTP_transf_3 PF12804.7 KEZ36934.1 - 3.3e-27 95.8 7.6 6.4e-27 94.9 7.6 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KEZ36934.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Mob_synth_C PF06463.13 KEZ36935.1 - 6.1e-37 126.4 0.0 8.4e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KEZ36935.1 - 1.4e-30 106.9 0.0 2.2e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ36935.1 - 3.2e-07 30.7 0.0 5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ36935.1 - 0.00026 21.1 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain ROK PF00480.20 KEZ36936.1 - 6.1e-15 55.5 0.5 1.9e-08 34.2 0.4 2.6 1 1 1 2 2 2 2 ROK family DUF3071 PF11268.8 KEZ36937.1 - 6.6e-46 156.4 1.5 1.1e-45 155.6 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) Desulfoferrod_N PF06397.12 KEZ36938.1 - 0.027 14.1 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Virul_fac_BrkB PF03631.15 KEZ36939.1 - 1.1e-46 159.5 17.4 1.4e-46 159.2 17.4 1.0 1 0 0 1 1 1 1 Virulence factor BrkB DUF1129 PF06570.11 KEZ36939.1 - 0.29 10.6 2.6 0.26 10.8 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) LytR_cpsA_psr PF03816.14 KEZ36940.1 - 1.2e-42 145.6 0.0 1.7e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Peptidase_M24 PF00557.24 KEZ36942.1 - 3.2e-47 160.9 0.0 4.2e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEZ36942.1 - 1.7e-22 79.5 0.0 3.2e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Lsr2 PF11774.8 KEZ36943.1 - 1.6e-41 140.9 1.0 1.8e-41 140.7 1.0 1.0 1 0 0 1 1 1 1 Lsr2 PIN_9 PF18477.1 KEZ36944.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 PIN like domain ABC_tran PF00005.27 KEZ36945.1 - 8.1e-26 91.2 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ36945.1 - 1.4e-08 35.0 0.9 0.002 18.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KEZ36945.1 - 0.0031 16.4 0.0 0.023 13.5 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KEZ36945.1 - 0.039 14.5 0.0 0.058 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KEZ36945.1 - 0.046 13.3 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ36945.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KEZ36945.1 - 0.18 11.2 0.0 2.1 7.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SpoIIE PF07228.12 KEZ36946.1 - 1.5e-37 129.4 1.4 1.5e-37 129.4 1.4 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) GAF_2 PF13185.6 KEZ36946.1 - 2.3e-23 83.0 14.8 5.3e-12 46.2 3.8 4.5 3 1 0 3 3 3 2 GAF domain PAS_4 PF08448.10 KEZ36946.1 - 1.3e-18 67.2 5.0 7.6e-15 55.1 0.3 3.3 2 0 0 2 2 2 2 PAS fold GAF PF01590.26 KEZ36946.1 - 1.7e-12 48.1 3.9 2e-06 28.4 0.1 2.9 2 0 0 2 2 2 2 GAF domain HATPase_c_2 PF13581.6 KEZ36946.1 - 1.3e-09 38.1 0.9 4.3e-09 36.4 0.4 2.2 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_3 PF08447.12 KEZ36946.1 - 3.4e-09 36.9 0.0 1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.6 KEZ36946.1 - 0.00021 21.6 2.7 0.31 11.4 0.2 3.3 3 0 0 3 3 3 2 GAF domain PAS PF00989.25 KEZ36946.1 - 0.00085 19.3 0.0 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KEZ36946.1 - 0.011 15.8 0.0 0.041 13.9 0.0 2.1 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 KEZ36946.1 - 0.091 13.0 0.0 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 PAS domain ATP-grasp_5 PF13549.6 KEZ36947.1 - 1e-50 172.3 0.0 2e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KEZ36947.1 - 1e-35 122.5 0.2 3.4e-32 111.1 0.1 3.5 2 1 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KEZ36947.1 - 2.4e-19 69.9 2.8 7e-19 68.4 2.1 2.3 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 KEZ36947.1 - 6.2e-09 36.4 0.5 1.9e-08 34.8 0.2 2.1 2 0 0 2 2 2 1 CoA binding domain Acetyltransf_1 PF00583.25 KEZ36947.1 - 2.8e-06 27.6 0.0 5.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KEZ36947.1 - 0.0028 18.3 0.0 0.0093 16.6 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEZ36947.1 - 0.0069 16.1 0.0 0.062 13.0 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GFO_IDH_MocA PF01408.22 KEZ36947.1 - 0.016 16.0 0.1 0.05 14.4 0.1 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Acetyltransf_4 PF13420.7 KEZ36947.1 - 0.047 13.8 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ36947.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ36947.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein K_oxygenase PF13434.6 KEZ36947.1 - 0.21 10.7 0.1 0.36 9.9 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Hist_deacetyl PF00850.19 KEZ36948.1 - 1.9e-71 241.0 0.0 2.3e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AMP-binding PF00501.28 KEZ36949.1 - 1.3e-47 162.4 0.0 1.6e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ36949.1 - 1.6e-07 32.2 0.9 7.8e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KEZ36949.1 - 2.1e-07 30.8 0.6 4.3e-07 29.7 0.6 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Sigma70_r3 PF04539.16 KEZ36950.1 - 4.9e-28 97.0 3.6 3.2e-26 91.2 0.8 2.9 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 KEZ36950.1 - 7.9e-22 76.8 0.1 1.9e-21 75.6 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KEZ36950.1 - 6.3e-18 64.0 6.0 6.5e-18 64.0 2.7 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 KEZ36950.1 - 2.3e-16 59.5 0.0 6.5e-16 58.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r1_1 PF03979.14 KEZ36950.1 - 2.1e-08 34.1 0.1 4.5e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 HTH_25 PF13413.6 KEZ36950.1 - 0.0013 18.6 0.7 0.44 10.5 0.0 3.1 2 0 0 2 2 2 2 Helix-turn-helix domain PolyA_pol_arg_C PF12626.7 KEZ36950.1 - 0.025 14.6 0.4 0.07 13.2 0.4 1.7 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Glyco_hydro_63 PF03200.16 KEZ36951.1 - 1.4e-15 57.0 0.0 1.5e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 KEZ36951.1 - 2e-09 36.8 0.0 1.1e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Trehalase Ribonuc_red_lgC PF02867.15 KEZ36952.1 - 2.2e-135 452.2 0.0 4.9e-135 451.0 0.0 1.5 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_2_N PF08471.10 KEZ36952.1 - 1.1e-19 70.4 0.0 4.8e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 Class II vitamin B12-dependent ribonucleotide reductase LAGLIDADG_3 PF14528.6 KEZ36952.1 - 2.9e-16 59.5 0.0 1.1e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 LAGLIDADG-like domain Ribonuc_red_lgN PF00317.21 KEZ36952.1 - 0.00015 21.7 0.0 0.0014 18.6 0.0 2.5 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain Intein_splicing PF14890.6 KEZ36952.1 - 0.19 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Intein splicing domain ATP-cone PF03477.16 KEZ36953.1 - 9.9e-14 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 ATP cone domain NMD3 PF04981.13 KEZ36953.1 - 0.051 13.0 0.2 0.067 12.7 0.2 1.2 1 0 0 1 1 1 0 NMD3 family Lar_restr_allev PF14354.6 KEZ36953.1 - 0.11 12.9 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Elf1 PF05129.13 KEZ36953.1 - 0.13 12.4 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LysM PF01476.20 KEZ36954.1 - 8e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain LexA_DNA_bind PF01726.16 KEZ36955.1 - 1.6e-28 98.2 0.1 2.4e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 KEZ36955.1 - 7.1e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like MarR_2 PF12802.7 KEZ36955.1 - 4.3e-08 32.9 0.3 9.3e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KEZ36955.1 - 0.0012 18.9 0.1 0.0021 18.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 KEZ36955.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.6 KEZ36955.1 - 0.0048 17.4 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Herpes_capsid PF06112.11 KEZ36955.1 - 0.012 15.7 0.2 0.019 15.1 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HTH_24 PF13412.6 KEZ36955.1 - 0.013 15.0 0.1 0.035 13.7 0.1 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KEZ36955.1 - 0.014 14.9 0.1 0.032 13.7 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 MarR PF01047.22 KEZ36955.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 KEZ36955.1 - 0.046 13.9 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 KEZ36955.1 - 0.055 13.4 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family CobN-Mg_chel PF02514.16 KEZ36955.1 - 0.061 11.1 0.0 0.078 10.7 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase HTH_36 PF13730.6 KEZ36955.1 - 0.24 11.4 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GTP-bdg_N PF13167.6 KEZ36956.1 - 1.2e-32 112.5 0.1 2.5e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 KEZ36956.1 - 8.6e-29 100.0 8.2 1.4e-28 99.3 7.0 1.9 2 0 0 2 2 2 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 KEZ36956.1 - 3.1e-21 75.6 0.0 6.5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ36956.1 - 1.3e-05 25.1 0.0 0.087 12.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KEZ36956.1 - 1.3e-05 24.7 0.0 2.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEZ36956.1 - 9.5e-05 22.5 0.1 0.0014 18.7 0.0 2.1 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 KEZ36956.1 - 0.00096 19.1 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 KEZ36956.1 - 0.0011 18.5 0.3 0.32 10.5 0.3 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KEZ36956.1 - 0.0042 16.5 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KEZ36956.1 - 0.064 13.6 3.2 0.21 12.0 0.3 2.5 1 1 1 2 2 2 0 AAA ATPase domain cobW PF02492.19 KEZ36956.1 - 0.39 10.3 3.7 6.2 6.4 0.1 3.1 2 2 2 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain HTH_18 PF12833.7 KEZ36957.1 - 1.9e-16 60.1 1.9 2.1e-16 59.9 0.5 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 KEZ36957.1 - 8.5e-07 28.9 0.0 0.0038 17.3 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_AsnC-type PF13404.6 KEZ36957.1 - 0.002 17.9 2.5 0.002 17.9 2.5 3.4 4 0 0 4 4 4 1 AsnC-type helix-turn-helix domain DDE_5 PF13546.6 KEZ36957.1 - 0.0046 16.4 0.4 0.0061 15.9 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.6 KEZ36957.1 - 0.2 11.2 0.6 0.54 9.9 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Glyoxalase PF00903.25 KEZ36958.1 - 1.4e-10 41.4 0.0 2.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEZ36958.1 - 4.3e-05 24.3 0.4 5.6e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KEZ36958.1 - 0.00057 19.8 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DAP_epimerase PF01678.19 KEZ36959.1 - 1.5e-57 193.0 0.2 3.2e-36 124.2 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 KEZ36959.1 - 0.13 11.7 1.1 20 4.5 0.1 2.9 3 0 0 3 3 3 0 Phenazine biosynthesis-like protein EAL PF00563.20 KEZ36960.1 - 9.9e-48 162.7 0.0 1.2e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 EAL domain Crp PF00325.20 KEZ36960.1 - 0.12 12.0 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family IPPT PF01715.17 KEZ36961.1 - 5.2e-70 235.8 0.0 6.1e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KEZ36961.1 - 0.00033 20.1 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase TetR_C_15 PF17918.1 KEZ36961.1 - 0.48 11.2 3.7 0.3 11.9 0.5 2.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Radical_SAM PF04055.21 KEZ36963.1 - 1e-27 97.6 0.0 1.5e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KEZ36963.1 - 1.8e-27 95.3 0.0 3.2e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 ABC_tran PF00005.27 KEZ36964.1 - 4e-35 121.3 0.0 5.2e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ36964.1 - 4.1e-10 40.0 0.0 7.7e-07 29.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ36964.1 - 4.8e-08 32.7 0.2 8.1e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ36964.1 - 2.2e-05 24.7 0.1 0.00011 22.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KEZ36964.1 - 0.00014 22.3 0.2 0.00032 21.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 KEZ36964.1 - 0.00031 19.5 0.0 0.39 9.3 0.0 2.0 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ36964.1 - 0.0035 17.1 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ36964.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KEZ36964.1 - 0.013 15.2 0.0 0.074 12.8 0.0 2.1 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 KEZ36964.1 - 0.014 15.9 0.0 0.026 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KEZ36964.1 - 0.014 15.6 0.4 0.23 11.7 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KEZ36964.1 - 0.016 14.0 0.3 1.4 7.6 0.2 2.9 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 KEZ36964.1 - 0.072 12.7 0.0 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEZ36964.1 - 0.11 12.9 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ36964.1 - 0.12 12.5 0.0 0.63 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KEZ36964.1 - 0.22 11.2 0.0 9.4 5.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KEZ36964.1 - 0.22 11.2 0.0 0.48 10.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ36964.1 - 0.29 11.6 0.0 0.43 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SBP_bac_3 PF00497.20 KEZ36965.1 - 4.6e-48 163.6 0.3 5.3e-48 163.4 0.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KEZ36965.1 - 3.1e-07 30.6 0.0 1e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 KEZ36965.1 - 0.049 13.2 0.1 0.28 10.7 0.1 2.0 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KEZ36965.1 - 0.07 13.1 0.2 6.2 6.7 0.1 2.2 1 1 1 2 2 2 0 NMT1/THI5 like BPD_transp_1 PF00528.22 KEZ36966.1 - 7.4e-17 61.7 15.1 8.7e-17 61.5 15.1 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component UPF0182 PF03699.13 KEZ36966.1 - 0.8 7.7 4.7 0.98 7.5 4.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) BPD_transp_1 PF00528.22 KEZ36967.1 - 4.4e-19 68.9 9.6 4.4e-19 68.9 9.6 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component P5-ATPase PF12409.8 KEZ36967.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF3552 PF12072.8 KEZ36968.1 - 1.2e-20 73.9 44.1 2.7e-19 69.4 44.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) HD PF01966.22 KEZ36968.1 - 1e-12 48.3 4.4 1e-12 48.3 4.4 2.4 2 0 0 2 2 2 1 HD domain KH_1 PF00013.29 KEZ36968.1 - 6e-06 26.0 0.0 2.4e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KEZ36968.1 - 0.00099 18.9 0.8 0.0024 17.7 0.2 2.0 2 0 0 2 2 2 1 KH domain ATP-synt_B PF00430.18 KEZ36968.1 - 0.0081 16.3 23.9 0.0081 16.3 23.9 3.6 3 1 1 4 4 4 1 ATP synthase B/B' CF(0) HDOD PF08668.12 KEZ36968.1 - 0.014 14.9 1.1 0.54 9.7 1.1 2.6 1 1 0 1 1 1 0 HDOD domain FAM76 PF16046.5 KEZ36968.1 - 1.4 8.2 2.5 2.5 7.4 2.5 1.4 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 KEZ36968.1 - 4.2 6.4 8.5 7.6 5.5 8.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RecX PF02631.16 KEZ36969.1 - 7.8e-27 94.2 1.3 2.8e-25 89.1 0.2 2.0 1 1 1 2 2 2 2 RecX family EH_Signature PF15611.6 KEZ36969.1 - 0.083 12.3 0.2 0.094 12.1 0.2 1.1 1 0 0 1 1 1 0 EH_Signature domain Corona_nucleoca PF00937.18 KEZ36969.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein RecA PF00154.21 KEZ36970.1 - 5.6e-142 471.8 0.9 6.6e-142 471.6 0.9 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 KEZ36970.1 - 1.5e-09 37.5 0.0 6.9e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KEZ36970.1 - 1.9e-07 30.7 1.6 3.1e-05 23.4 1.6 2.7 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 KEZ36970.1 - 0.0004 20.4 0.0 0.00084 19.3 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KEZ36970.1 - 0.00086 19.1 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEZ36970.1 - 0.0057 16.3 0.6 0.093 12.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain CobU PF02283.16 KEZ36970.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 KEZ36970.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ36970.1 - 0.089 13.2 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DEAD_assoc PF08494.11 KEZ36971.1 - 1.4e-75 253.3 0.2 2.9e-75 252.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/H associated DEAD PF00270.29 KEZ36971.1 - 9.9e-25 87.3 0.0 1.7e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ36971.1 - 1.9e-10 41.0 0.0 7e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_25 PF13481.6 KEZ36971.1 - 7.5e-05 22.4 0.4 0.00031 20.4 0.4 2.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KEZ36971.1 - 0.00026 21.0 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEZ36971.1 - 0.11 12.8 0.0 0.62 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sigma70_r2 PF04542.14 KEZ36972.1 - 1.1e-12 47.6 0.8 1.9e-12 46.7 0.8 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 KEZ36972.1 - 0.0002 21.3 2.5 0.00033 20.6 2.5 1.3 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4_2 PF08281.12 KEZ36972.1 - 0.00034 20.2 0.3 0.00077 19.1 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 KEZ36972.1 - 0.011 15.2 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Lant_dehydr_C PF14028.6 KEZ36973.1 - 3.9e-26 92.3 2.2 8.6e-26 91.2 2.2 1.6 1 1 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term LANC_like PF05147.13 KEZ36974.1 - 7.9e-23 80.6 0.0 6.1e-13 48.1 0.0 2.1 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein PCMT PF01135.19 KEZ36974.1 - 6.1e-05 22.9 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Phage_int_SAM_1 PF02899.17 KEZ36975.1 - 0.0016 18.7 0.0 0.0019 18.5 0.0 1.1 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain HTH_OrfB_IS605 PF12323.8 KEZ36976.1 - 7.8e-08 31.7 0.5 7.3e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain AAT PF03417.16 KEZ36977.1 - 1.6e-16 60.7 0.0 2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DNA_Packaging_2 PF11123.8 KEZ36977.1 - 0.1 12.8 0.0 0.66 10.2 0.0 2.0 2 0 0 2 2 2 0 DNA packaging protein Acetyltransf_3 PF13302.7 KEZ36978.1 - 2.6e-17 63.8 0.1 3e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KEZ36980.1 - 1e-54 185.8 0.0 1.3e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme tRNA-synt_1g PF09334.11 KEZ36981.1 - 1.3e-58 198.6 0.0 1.7e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) Cupin_2 PF07883.11 KEZ36981.1 - 3.1e-14 52.4 1.6 6.6e-14 51.4 1.6 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KEZ36981.1 - 3.5e-08 33.4 0.1 1.1e-07 31.9 0.1 1.8 1 0 0 1 1 1 1 AraC-like ligand binding domain tRNA-synt_1 PF00133.22 KEZ36981.1 - 0.00018 19.9 0.0 0.0028 16.0 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KEZ36981.1 - 0.0016 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Cupin_1 PF00190.22 KEZ36981.1 - 0.002 17.8 0.1 0.0038 16.8 0.1 1.4 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.16 KEZ36981.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Auxin binding protein DAO PF01266.24 KEZ36982.1 - 2e-29 103.3 8.9 2.7e-29 102.9 8.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ36982.1 - 1.5e-06 28.3 0.8 0.06 13.3 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KEZ36982.1 - 3.1e-05 23.4 0.2 5.1e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ36982.1 - 0.00069 18.9 0.6 0.018 14.3 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ36982.1 - 0.00094 19.4 0.5 0.0025 18.0 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ36982.1 - 0.001 18.2 1.6 0.05 12.6 1.7 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.21 KEZ36982.1 - 0.0031 16.9 1.1 0.0052 16.2 1.1 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 KEZ36982.1 - 0.0055 17.2 2.1 0.063 13.8 2.8 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ36982.1 - 0.024 13.4 1.4 0.77 8.4 2.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KEZ36982.1 - 0.041 13.0 8.2 0.22 10.5 8.2 2.0 1 1 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KEZ36982.1 - 0.043 13.9 0.1 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ36982.1 - 0.29 11.4 1.2 0.69 10.2 1.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KEZ36982.1 - 0.31 10.3 1.5 0.54 9.5 1.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KEZ36982.1 - 0.74 9.4 2.6 0.46 10.1 0.6 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 KEZ36983.1 - 2.3e-85 286.8 0.0 2.8e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ36983.1 - 6.6e-13 48.6 0.0 1.5e-10 40.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ36983.1 - 1.1e-06 28.1 0.0 5.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ36983.1 - 9.4e-06 25.7 0.1 0.0082 16.1 0.1 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ36983.1 - 0.015 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Acyl-CoA_dh_1 PF00441.24 KEZ36984.1 - 4.5e-41 140.5 7.8 8.1e-41 139.7 7.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ36984.1 - 1.3e-18 66.9 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ36984.1 - 2.5e-18 66.6 12.7 2.5e-18 66.6 12.7 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ36984.1 - 1.8e-09 38.3 0.8 8.1e-09 36.1 0.2 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Haem_oxygenas_2 PF14518.6 KEZ36985.1 - 2.4e-18 66.5 1.9 5.6e-16 58.8 0.5 2.5 2 0 0 2 2 2 2 Iron-containing redox enzyme Lipase_GDSL_2 PF13472.6 KEZ36986.1 - 1e-16 61.9 0.0 1.2e-16 61.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ36986.1 - 2.9e-05 24.2 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AurF PF11583.8 KEZ36987.1 - 5.8e-15 55.3 5.1 1.3e-14 54.2 5.1 1.6 1 1 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF Ald_deCOase PF11266.8 KEZ36987.1 - 5.3e-05 23.0 0.1 0.00034 20.4 0.0 1.9 1 1 0 2 2 2 1 Long-chain fatty aldehyde decarbonylase Ribonuc_red_sm PF00268.21 KEZ36987.1 - 0.00056 19.5 0.0 0.0086 15.6 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, small chain Ferritin_2 PF13668.6 KEZ36987.1 - 0.0028 17.9 0.1 0.0057 16.9 0.1 1.5 1 0 0 1 1 1 1 Ferritin-like domain Phenol_Hydrox PF02332.18 KEZ36987.1 - 0.0056 16.2 0.5 0.068 12.7 0.5 2.2 1 1 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase DUF455 PF04305.14 KEZ36987.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF455) PP-binding PF00550.25 KEZ36989.1 - 4.2e-05 23.8 1.5 5.2e-05 23.5 1.5 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KEZ36990.1 - 7.1e-60 202.8 0.0 9.1e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme KdpD PF02702.17 KEZ36991.1 - 6.2e-99 329.7 0.1 9.4e-99 329.1 0.1 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 KEZ36991.1 - 1e-20 73.5 14.8 2.3e-20 72.4 14.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 KEZ36991.1 - 1e-18 67.9 0.0 2.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ36991.1 - 2.8e-12 46.5 1.8 8.5e-12 44.9 1.8 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 KEZ36991.1 - 1.3e-06 29.0 1.2 1.3e-06 29.0 1.2 3.2 2 1 0 2 2 2 1 Universal stress protein family DUF3382 PF11862.8 KEZ36991.1 - 0.074 13.3 7.9 0.24 11.7 7.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DUF417 PF04224.12 KEZ36991.1 - 0.13 11.8 0.8 0.23 11.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 PhoR PF11808.8 KEZ36991.1 - 3.8 8.0 7.5 1.4 9.4 3.8 2.2 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR Response_reg PF00072.24 KEZ36992.1 - 1.2e-27 96.3 0.0 1.6e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ36992.1 - 2.3e-17 62.8 0.1 1.7e-16 60.0 0.0 2.2 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal B12-binding PF02310.19 KEZ36992.1 - 0.047 13.7 0.2 0.081 13.0 0.2 1.3 1 0 0 1 1 1 0 B12 binding domain KdpC PF02669.15 KEZ36993.1 - 2.8e-58 196.8 0.0 5.1e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 K+-transporting ATPase, c chain Hydrolase PF00702.26 KEZ36994.1 - 9.1e-21 75.1 0.7 1.3e-20 74.6 0.7 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ36994.1 - 8.5e-06 25.7 1.1 0.00015 21.6 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ36994.1 - 0.00082 19.8 0.0 0.0049 17.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF759 PF05537.11 KEZ36994.1 - 0.027 13.4 0.1 0.056 12.3 0.0 1.5 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) Cadherin_4 PF17803.1 KEZ36994.1 - 0.18 12.5 0.9 0.34 11.6 0.9 1.4 1 0 0 1 1 1 0 Bacterial cadherin-like domain E1-E2_ATPase PF00122.20 KEZ36995.1 - 3.6e-33 114.6 0.4 5.9e-33 113.9 0.4 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ36995.1 - 0.00064 20.1 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF5345 PF17280.2 KEZ36995.1 - 0.03 14.3 0.2 0.076 13.0 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) KdpA PF03814.15 KEZ36996.1 - 9.4e-226 750.2 23.8 1.1e-225 750.0 23.8 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit Response_reg PF00072.24 KEZ36997.1 - 3.2e-26 91.7 0.0 4.9e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ36997.1 - 2.1e-22 79.0 0.0 8.2e-22 77.1 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 KEZ36997.1 - 0.014 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 MarR family DUF72 PF01904.18 KEZ36998.1 - 1.2e-49 169.4 0.5 1.4e-49 169.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 MazE_antitoxin PF04014.18 KEZ36999.1 - 3.3e-05 23.7 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin MraZ PF02381.18 KEZ36999.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like PIN PF01850.21 KEZ37000.1 - 9.4e-08 32.6 0.0 1.5e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 PIN domain HxlR PF01638.17 KEZ37001.1 - 1.1e-30 105.4 0.1 1.2e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_12 PF08461.10 KEZ37001.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain PadR PF03551.14 KEZ37001.1 - 0.014 15.3 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 KEZ37001.1 - 0.11 12.6 0.3 0.21 11.6 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain NAD_binding_2 PF03446.15 KEZ37002.1 - 1.7e-10 41.3 0.1 2.2e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ37002.1 - 9.9e-05 22.8 0.2 0.0002 21.8 0.2 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KEZ37002.1 - 0.0016 18.1 0.2 0.0036 16.9 0.2 1.6 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KEZ37002.1 - 0.0062 16.5 0.7 0.021 14.8 0.1 1.8 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KEZ37003.1 - 2.3e-17 63.6 0.0 4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ37003.1 - 2.4e-05 24.8 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KEZ37003.1 - 5.4e-05 22.9 0.1 8.9e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KEZ37003.1 - 0.00012 22.0 0.1 0.00029 20.8 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ37003.1 - 0.00043 20.3 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ37003.1 - 0.00054 20.2 0.0 0.0085 16.3 0.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KEZ37003.1 - 0.00072 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KEZ37003.1 - 0.038 14.2 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KEZ37003.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HATPase_c_4 PF13749.6 KEZ37004.1 - 2.4e-16 59.6 0.0 6.4e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Putative ATP-dependent DNA helicase recG C-terminal AlbA_2 PF04326.14 KEZ37004.1 - 1.4e-09 38.3 0.0 2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Putative DNA-binding domain HTH_20 PF12840.7 KEZ37004.1 - 1.1e-06 28.6 2.9 2.7e-06 27.4 0.4 2.8 3 0 0 3 3 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ37004.1 - 1.6e-06 27.9 1.6 9e-06 25.5 0.7 2.7 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 KEZ37004.1 - 2.3e-06 27.4 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 KEZ37004.1 - 8.2e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DprA_WH PF17782.1 KEZ37004.1 - 5.2e-05 23.3 3.4 5.2e-05 23.3 1.0 2.3 2 0 0 2 2 2 1 DprA winged helix domain HTH_24 PF13412.6 KEZ37004.1 - 8e-05 22.1 0.2 0.00016 21.1 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 KEZ37004.1 - 0.00022 20.8 1.6 0.00058 19.5 0.7 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 KEZ37004.1 - 0.0015 18.6 1.7 0.032 14.4 0.6 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain AbiEi_4 PF13338.6 KEZ37004.1 - 0.0017 18.4 1.9 0.053 13.7 0.7 3.4 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin HTH_IclR PF09339.10 KEZ37004.1 - 0.0026 17.5 2.0 0.014 15.2 0.3 2.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ37004.1 - 0.013 14.9 0.3 0.053 12.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_41 PF14502.6 KEZ37004.1 - 0.016 14.9 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 KEZ37004.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ37004.1 - 0.028 14.4 0.2 0.098 12.6 0.2 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 KEZ37004.1 - 0.047 13.5 0.9 0.047 13.5 0.9 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_10 PF04967.12 KEZ37004.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain Rrf2 PF02082.20 KEZ37004.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 KEZ37004.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 MarR family TFIIE_alpha PF02002.17 KEZ37004.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit RPA_C PF08784.11 KEZ37004.1 - 0.081 13.6 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal HTH_9 PF08221.11 KEZ37004.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_11 PF08279.12 KEZ37004.1 - 0.1 12.5 0.1 0.42 10.6 0.1 1.9 2 0 0 2 2 2 0 HTH domain HTH_8 PF02954.19 KEZ37004.1 - 0.14 12.0 0.2 0.37 10.6 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family CBM65_1 PF18259.1 KEZ37005.1 - 0.12 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding module 65 domain 1 Uma2 PF05685.12 KEZ37006.1 - 2.2e-21 76.2 0.0 2.6e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease ADH_zinc_N PF00107.26 KEZ37007.1 - 5.5e-09 36.1 0.6 5.5e-09 36.1 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ37007.1 - 8.4e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 KEZ37007.1 - 0.49 10.5 2.2 2.2 8.4 0.7 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus BenE PF03594.13 KEZ37008.1 - 1.2e-64 218.5 29.7 1.3e-64 218.3 29.7 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein BenE PF03594.13 KEZ37009.1 - 1.6e-18 66.7 10.9 1.8e-18 66.5 10.9 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein EHN PF06441.12 KEZ37011.1 - 1.7e-22 79.8 0.0 2.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KEZ37011.1 - 2e-08 34.2 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Radical_SAM PF04055.21 KEZ37012.1 - 1.3e-11 45.1 0.1 3.1e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ37012.1 - 0.0013 19.0 0.0 0.0051 17.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ37012.1 - 0.0018 18.4 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain BtrH_N PF14399.6 KEZ37012.1 - 0.17 12.1 0.0 4.2 7.6 0.0 2.5 2 1 1 3 3 3 0 Butirosin biosynthesis protein H, N-terminal Stealth_CR1 PF17101.5 KEZ37012.1 - 0.62 9.9 2.8 8.9 6.1 0.0 2.8 3 0 0 3 3 3 0 Stealth protein CR1, conserved region 1 MFS_1 PF07690.16 KEZ37014.1 - 2.5e-60 204.3 56.2 1.6e-50 172.1 41.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ37014.1 - 0.45 9.3 19.0 0.74 8.6 7.5 2.1 2 0 0 2 2 2 0 MFS_1 like family OATP PF03137.20 KEZ37014.1 - 4 5.6 11.3 0.9 7.7 0.0 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GMC_oxred_C PF05199.13 KEZ37015.1 - 3e-22 79.7 0.1 2e-21 77.0 0.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KEZ37015.1 - 6.9e-13 48.6 0.0 2.6e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KEZ37015.1 - 5.1e-06 26.3 3.5 7.4e-05 22.5 1.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ37015.1 - 5.8e-06 26.5 1.3 2.4e-05 24.4 1.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ37015.1 - 0.00013 21.2 5.1 0.00074 18.7 3.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ37015.1 - 0.00046 19.5 0.6 0.0007 18.9 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ37015.1 - 0.0013 18.0 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEZ37015.1 - 0.0051 16.5 1.0 0.01 15.5 1.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KEZ37015.1 - 0.0062 15.7 1.0 0.0081 15.3 1.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A ThiF PF00899.21 KEZ37015.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 ThiF family Thi4 PF01946.17 KEZ37015.1 - 0.018 14.3 0.2 0.037 13.3 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KEZ37015.1 - 0.039 13.3 4.2 0.056 12.8 4.2 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ37015.1 - 0.045 12.8 0.3 0.077 12.0 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KEZ37015.1 - 0.082 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KEZ37015.1 - 0.12 11.0 0.8 0.17 10.6 0.8 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KEZ37015.1 - 0.92 8.3 2.2 1.3 7.8 2.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF2917 PF11142.8 KEZ37015.1 - 1.3 8.5 3.9 2 7.9 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2917) Glycos_transf_1 PF00534.20 KEZ37017.1 - 1.3e-37 129.0 0.0 1.8e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ37017.1 - 2.2e-32 112.3 0.5 4.9e-32 111.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ37017.1 - 1.4e-15 58.1 10.1 1.4e-15 58.1 10.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ37017.1 - 2e-15 57.2 3.2 2.1e-15 57.1 1.6 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ37017.1 - 1.9e-09 37.8 0.0 3.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peripla_BP_4 PF13407.6 KEZ37017.1 - 0.14 11.7 0.4 13 5.3 0.0 2.1 1 1 1 2 2 2 0 Periplasmic binding protein domain DegT_DnrJ_EryC1 PF01041.17 KEZ37018.1 - 1.3e-84 284.6 0.0 1.6e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KEZ37018.1 - 0.0057 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEZ37018.1 - 0.057 12.4 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V ADH_N PF08240.12 KEZ37019.1 - 2.2e-20 72.5 0.0 3.4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ37019.1 - 1.6e-14 54.0 1.5 9.6e-14 51.5 1.5 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ37019.1 - 3.6e-07 29.9 2.0 9.6e-07 28.5 2.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KEZ37019.1 - 7.1e-05 22.2 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEZ37019.1 - 0.11 12.4 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TylF PF05711.11 KEZ37020.1 - 2.6e-16 59.7 0.0 3.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 KEZ37020.1 - 3.7e-06 27.9 0.0 5.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Radical_SAM PF04055.21 KEZ37021.1 - 1.3e-18 68.0 0.0 6e-18 65.8 0.0 2.0 1 1 1 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 KEZ37021.1 - 1.5e-08 35.0 0.2 1.5e-08 35.0 0.2 1.9 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 KEZ37021.1 - 3.9e-07 30.4 0.0 8.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ37021.1 - 5.7e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain PIG-L PF02585.17 KEZ37022.1 - 1e-14 55.3 0.8 1.6e-14 54.7 0.8 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase APH PF01636.23 KEZ37023.1 - 2.8e-27 96.2 11.5 3.4e-27 95.9 11.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KEZ37023.1 - 0.0036 16.5 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 1 Fructosamine kinase RIO1 PF01163.22 KEZ37023.1 - 0.012 15.2 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KEZ37023.1 - 0.056 12.8 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 KEZ37023.1 - 0.065 12.6 0.1 3.3 7.0 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_3 PF00202.21 KEZ37024.1 - 1.4e-41 142.5 0.0 5.9e-23 81.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III B12-binding PF02310.19 KEZ37025.1 - 2.6e-19 69.4 0.1 3e-18 66.0 0.1 2.6 1 1 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 KEZ37025.1 - 7.3e-15 55.7 0.1 3e-14 53.7 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Glyco_transf_4 PF13439.6 KEZ37025.1 - 0.022 14.7 1.6 0.2 11.6 0.8 2.4 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Fer4_12 PF13353.6 KEZ37025.1 - 0.031 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DAO PF01266.24 KEZ37026.1 - 2.3e-34 119.6 7.4 2.7e-34 119.3 7.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ37026.1 - 0.00076 18.7 10.3 0.014 14.5 10.3 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ37026.1 - 0.0012 18.2 0.2 0.0033 16.7 0.2 1.7 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KEZ37026.1 - 0.0027 16.9 0.5 0.34 9.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KEZ37026.1 - 0.0045 16.3 1.1 0.11 11.7 1.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ37026.1 - 0.014 14.7 0.6 0.021 14.1 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KEZ37026.1 - 0.1 13.2 0.6 0.36 11.4 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ37026.1 - 3.1 7.8 4.5 1.4 8.9 0.4 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FmrO PF07091.11 KEZ37027.1 - 1.2e-128 428.0 0.5 1.3e-128 427.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.12 KEZ37028.1 - 4.7e-11 43.2 0.0 8.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37028.1 - 1.6e-07 32.0 0.0 3.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37028.1 - 0.0014 19.3 0.0 0.0023 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ37028.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KEZ37028.1 - 0.024 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ37028.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KEZ37028.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase GFO_IDH_MocA PF01408.22 KEZ37029.1 - 7.1e-20 72.0 0.0 1.1e-19 71.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEZ37029.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ldh_1_N PF00056.23 KEZ37029.1 - 0.0034 17.5 0.0 0.0081 16.3 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ37029.1 - 0.008 16.4 0.3 0.018 15.3 0.3 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KEZ37029.1 - 0.015 15.9 0.2 0.028 15.0 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KEZ37029.1 - 0.05 13.2 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gp_dh_N PF00044.24 KEZ37029.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CMD PF02627.20 KEZ37030.1 - 3.3e-18 65.5 4.6 5.4e-18 64.8 0.8 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family TP_methylase PF00590.20 KEZ37032.1 - 2.6e-31 109.2 0.8 4.3e-31 108.5 0.8 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TGT PF01702.18 KEZ37033.1 - 7.3e-77 258.9 0.0 9.2e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Exc PF07825.11 KEZ37033.1 - 0.094 12.7 0.0 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Excisionase-like protein QueC PF06508.13 KEZ37034.1 - 5.1e-75 251.6 0.0 5.8e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KEZ37034.1 - 3.1e-08 33.7 0.1 4.4e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 KEZ37034.1 - 0.012 14.4 0.2 0.018 13.9 0.2 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.19 KEZ37034.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 KEZ37034.1 - 0.026 14.1 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 KEZ37034.1 - 0.041 13.0 0.1 0.09 11.9 0.0 1.5 2 0 0 2 2 2 0 NAD synthase Radical_SAM PF04055.21 KEZ37035.1 - 2.8e-05 24.6 0.0 3.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KEZ37035.1 - 0.05 13.7 0.2 0.089 12.9 0.2 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain PTPS PF01242.19 KEZ37036.1 - 3.3e-35 120.7 0.0 3.8e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase FmrO PF07091.11 KEZ37037.1 - 4.9e-123 409.6 2.0 7.4e-123 409.0 2.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.14 KEZ37037.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KEZ37037.1 - 0.045 14.5 0.0 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain QueF PF14489.6 KEZ37038.1 - 5.1e-22 77.8 0.0 6.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 QueF-like protein QueF_N PF14819.6 KEZ37038.1 - 0.0085 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DDE_Tnp_4 PF13359.6 KEZ37039.1 - 1.9e-30 105.6 0.0 2.4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ37039.1 - 5.7e-14 52.3 0.1 7.1e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 KEZ37039.1 - 1.5e-05 24.7 0.0 3.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF4096 PF13340.6 KEZ37040.1 - 1.2e-27 96.0 0.1 1.2e-27 96.0 0.1 2.1 3 0 0 3 3 3 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 KEZ37040.1 - 9.6e-21 74.4 0.8 3.5e-20 72.6 0.8 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KEZ37040.1 - 3.8e-11 43.2 0.1 6.4e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 KEZ37041.1 - 1.7e-17 63.7 0.0 2.1e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_integrase PF00589.22 KEZ37042.1 - 4e-13 49.5 0.0 6.4e-12 45.6 0.0 2.3 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ37042.1 - 7.5e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_4 PF14657.6 KEZ37042.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain Wtap PF17098.5 KEZ37042.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Phage_integrase PF00589.22 KEZ37045.1 - 1.5e-14 54.2 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ37045.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain HTH_31 PF13560.6 KEZ37048.1 - 0.024 15.0 0.1 0.024 15.0 0.1 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain UCR_Fe-S_N PF10399.9 KEZ37048.1 - 7 6.1 8.9 0.13 11.7 0.9 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal WD40 PF00400.32 KEZ37051.1 - 2.4e-41 138.9 5.4 1.3e-07 32.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Pkinase PF00069.25 KEZ37051.1 - 1.3e-33 116.6 0.0 1.6e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ge1_WD40 PF16529.5 KEZ37051.1 - 5.8e-22 78.1 4.1 0.00028 19.9 0.0 6.9 1 1 6 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase_Tyr PF07714.17 KEZ37051.1 - 6.3e-20 71.5 0.0 7.8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KEZ37051.1 - 2.3e-14 53.4 0.0 0.4 11.0 0.0 7.0 2 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KEZ37051.1 - 1.1e-08 34.8 1.0 0.68 9.9 0.1 5.3 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KEZ37051.1 - 0.00045 19.6 2.8 28 3.9 0.0 5.4 6 1 1 7 7 7 0 Neuroblastoma-amplified sequence, N terminal APH PF01636.23 KEZ37051.1 - 0.0026 17.7 0.0 0.0026 17.7 0.0 3.1 2 2 1 3 3 3 1 Phosphotransferase enzyme family Nup160 PF11715.8 KEZ37051.1 - 0.005 15.5 3.8 10 4.6 0.0 4.7 2 1 1 5 5 5 1 Nucleoporin Nup120/160 GBP_repeat PF02526.14 KEZ37051.1 - 0.0081 15.8 0.1 5.3 6.9 0.0 2.7 2 0 0 2 2 2 2 Glycophorin-binding protein eIF2A PF08662.11 KEZ37051.1 - 0.017 15.0 0.0 13 5.6 0.0 3.2 1 1 3 4 4 4 0 Eukaryotic translation initiation factor eIF2A Kdo PF06293.14 KEZ37051.1 - 0.025 14.0 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ37051.1 - 0.09 12.4 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family WD40_3 PF15911.5 KEZ37051.1 - 0.15 12.1 0.0 35 4.5 0.0 3.1 1 1 1 2 2 2 0 WD domain, G-beta repeat DUF2207 PF09972.9 KEZ37053.1 - 1.3 7.7 7.2 1.3 7.7 7.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VirB8 PF04335.13 KEZ37054.1 - 0.13 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 VirB8 protein FtsK_SpoIIIE PF01580.18 KEZ37056.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ37056.1 - 0.077 13.4 0.3 0.21 11.9 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain Resolvase PF00239.21 KEZ37057.1 - 2e-12 47.4 2.5 8.7e-12 45.4 0.1 2.3 2 0 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 KEZ37057.1 - 1.3e-08 35.2 0.0 2.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 KEZ37057.1 - 0.0042 17.6 0.1 0.0042 17.6 0.1 1.9 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain ParG PF09274.10 KEZ37058.1 - 0.12 12.5 0.8 0.22 11.7 0.4 1.6 2 0 0 2 2 2 0 ParG DUF4106 PF13388.6 KEZ37058.1 - 3.2 6.9 9.2 3.4 6.8 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CLP_protease PF00574.23 KEZ37061.1 - 1e-25 90.7 0.0 1.7e-25 90.0 0.0 1.3 1 1 0 1 1 1 1 Clp protease SDH_sah PF01972.16 KEZ37061.1 - 0.00013 21.1 0.1 0.0002 20.5 0.1 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Peptidase_S49 PF01343.18 KEZ37061.1 - 0.014 15.3 0.6 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 T7SS_ESX_EspC PF10824.8 KEZ37061.1 - 0.079 13.4 0.2 0.079 13.4 0.2 2.8 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Hemerythrin PF01814.23 KEZ37061.1 - 1.2 9.7 3.7 4.4 7.9 0.2 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain TMEM213 PF15192.6 KEZ37062.1 - 0.006 16.5 1.0 0.0082 16.1 1.0 1.3 1 0 0 1 1 1 1 TMEM213 family DUF4407 PF14362.6 KEZ37062.1 - 0.33 10.3 0.8 0.33 10.3 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Histone_HNS PF00816.21 KEZ37063.1 - 0.03 15.2 0.0 0.03 15.2 0.0 2.9 2 1 1 3 3 3 0 H-NS histone family Phage_Mu_Gam PF07352.12 KEZ37063.1 - 0.043 13.7 0.2 0.19 11.7 0.2 1.8 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein MscS_porin PF12795.7 KEZ37063.1 - 0.35 10.4 8.3 0.44 10.1 1.7 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF2255 PF10012.9 KEZ37065.1 - 0.074 13.2 0.3 0.074 13.2 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) BiPBP_C PF06832.12 KEZ37065.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family D5_N PF08706.11 KEZ37066.1 - 3.2e-18 66.4 1.3 3.7e-18 66.2 0.1 1.8 2 0 0 2 2 2 1 D5 N terminal like RepB_primase PF16793.5 KEZ37066.1 - 1.4e-06 28.6 0.1 2.8e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 RepB DNA-primase from phage plasmid DUF5319 PF17252.2 KEZ37066.1 - 0.15 12.3 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5319) Terminase_3 PF04466.13 KEZ37070.1 - 1e-11 44.8 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Phage terminase large subunit Terminase_6 PF03237.15 KEZ37070.1 - 6.8e-10 39.0 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Terminase-like family DEAD PF00270.29 KEZ37070.1 - 1.3e-05 25.0 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KEZ37070.1 - 0.13 11.6 0.3 4 6.8 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein AAA_30 PF13604.6 KEZ37070.1 - 0.18 11.5 0.1 0.75 9.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Terminase_3C PF17288.2 KEZ37070.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.6 1 1 0 1 1 1 0 Terminase RNAseH like domain AAA PF00004.29 KEZ37070.1 - 0.21 12.0 0.6 2.8 8.4 0.6 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_17 PF12728.7 KEZ37073.1 - 0.0011 19.1 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HHH PF00633.23 KEZ37073.1 - 0.04 13.8 0.2 1.5 8.8 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif Helitron_like_N PF14214.6 KEZ37076.1 - 0.34 11.1 0.6 3 8.0 0.1 2.1 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus HTH_17 PF12728.7 KEZ37077.1 - 1.7e-13 50.5 0.0 1.8e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ37077.1 - 3.3e-05 23.5 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain MerR_1 PF13411.6 KEZ37077.1 - 0.00017 21.6 0.1 0.0002 21.4 0.1 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_Tnp_1 PF01527.20 KEZ37077.1 - 0.0084 16.4 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Transposase Phage_AlpA PF05930.12 KEZ37077.1 - 0.043 13.6 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_3 PF01381.22 KEZ37077.1 - 0.046 13.8 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix Terminase_5 PF06056.12 KEZ37077.1 - 0.054 13.4 0.2 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1_2 PF13022.6 KEZ37077.1 - 0.082 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF1348 PF07080.11 KEZ37078.1 - 0.17 11.8 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) tRNA_edit PF04073.15 KEZ37079.1 - 4.8e-22 78.3 0.0 5.7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain FTR1 PF03239.14 KEZ37080.1 - 2.1e-41 142.1 14.1 3.2e-41 141.5 14.1 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family Peptidase_M75 PF09375.10 KEZ37080.1 - 1.9e-13 50.6 0.0 5.1e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 Imelysin DEC-1_N PF04625.13 KEZ37080.1 - 5.7 5.8 10.2 9.7 5.1 10.2 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Dyp_perox PF04261.12 KEZ37081.1 - 3e-101 338.7 0.0 3.5e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF839 PF05787.13 KEZ37082.1 - 3.3e-59 201.5 0.0 5.1e-48 164.5 0.1 3.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 KEZ37082.1 - 2.8 7.9 7.3 0.41 10.6 0.2 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence AAA PF00004.29 KEZ37083.1 - 2.3e-26 92.8 0.0 3.7e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Acetyltransf_1 PF00583.25 KEZ37083.1 - 2e-09 37.7 0.0 3.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ37083.1 - 2.9e-07 30.5 0.0 5.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 KEZ37083.1 - 3.7e-06 27.4 0.1 0.0068 16.8 0.0 2.7 1 1 1 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KEZ37083.1 - 1.1e-05 25.1 0.5 2.5e-05 24.0 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KEZ37083.1 - 0.00012 22.1 0.0 0.00096 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ37083.1 - 0.00014 22.2 0.1 0.039 14.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 KEZ37083.1 - 0.00016 22.0 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RuvB_N PF05496.12 KEZ37083.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEZ37083.1 - 0.002 18.6 0.0 0.0038 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KEZ37083.1 - 0.0059 16.7 0.0 0.028 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KEZ37083.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ37083.1 - 0.025 14.5 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.13 KEZ37083.1 - 0.03 13.5 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KEZ37083.1 - 0.031 14.5 0.0 0.078 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEZ37083.1 - 0.031 14.0 0.0 0.088 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEZ37083.1 - 0.034 13.5 0.0 0.25 10.7 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IPT PF01745.16 KEZ37083.1 - 0.044 13.2 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase AAA_25 PF13481.6 KEZ37083.1 - 0.052 13.1 0.7 0.28 10.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 KEZ37083.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KEZ37083.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KEZ37083.1 - 0.073 13.0 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KEZ37083.1 - 0.1 12.9 0.0 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KEZ37083.1 - 0.11 12.6 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.6 KEZ37083.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 KEZ37083.1 - 0.14 12.2 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 KEZ37083.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.5 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 KEZ37083.1 - 0.22 10.8 0.0 4.7 6.5 0.0 2.1 2 0 0 2 2 2 0 KaiC Flavoprotein PF02441.19 KEZ37084.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein baeRF_family2 PF18844.1 KEZ37085.1 - 6.9e-44 149.5 13.8 1.2e-43 148.7 13.8 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 baeRF_family10 PF18854.1 KEZ37085.1 - 8e-17 61.8 5.1 3.3e-16 59.8 5.1 2.0 1 1 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KEZ37085.1 - 8.6e-17 61.7 11.8 8.6e-17 61.7 11.8 2.5 3 1 0 3 3 3 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family3 PF18845.1 KEZ37085.1 - 0.0004 20.7 0.6 0.00067 20.0 0.6 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 baeRF_family12 PF18856.1 KEZ37085.1 - 0.12 13.0 0.1 0.56 10.8 0.0 2.0 1 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 tRNA-synt_2b PF00587.25 KEZ37086.1 - 4.5e-29 101.7 0.0 6.7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEZ37086.1 - 4.6e-05 23.5 0.0 8.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF5102 PF17104.5 KEZ37087.1 - 0.024 14.7 5.1 0.041 13.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Pkinase PF00069.25 KEZ37088.1 - 3.4e-10 39.7 0.0 1.9e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KEZ37088.1 - 0.0064 16.4 4.2 0.045 13.7 0.1 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family FHA PF00498.26 KEZ37089.1 - 7.3e-10 39.1 0.0 0.00015 22.1 0.0 2.4 2 0 0 2 2 2 2 FHA domain Polyketide_cyc2 PF10604.9 KEZ37090.1 - 0.41 10.9 4.5 2.5 8.3 0.1 3.2 4 0 0 4 4 4 0 Polyketide cyclase / dehydrase and lipid transport SpoIIE PF07228.12 KEZ37091.1 - 2e-05 24.6 0.1 3.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KEZ37091.1 - 0.0013 18.4 1.0 0.0066 16.1 1.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KEZ37091.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Abhydrolase_1 PF00561.20 KEZ37094.1 - 7.1e-24 84.8 0.4 7.3e-22 78.2 0.7 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ37094.1 - 4.2e-20 73.3 16.3 4.2e-20 73.3 16.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ37094.1 - 4.7e-20 71.9 2.6 3.6e-18 65.7 2.6 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KEZ37094.1 - 2.9e-05 22.9 0.0 5.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 KEZ37094.1 - 3.3e-05 23.7 0.7 0.0091 15.7 0.3 2.3 2 0 0 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 KEZ37094.1 - 0.0001 22.5 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KEZ37094.1 - 0.00063 19.5 0.1 0.0014 18.4 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 KEZ37094.1 - 0.0021 17.8 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KEZ37094.1 - 0.037 13.3 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 KEZ37094.1 - 0.069 12.6 0.1 0.23 10.9 0.1 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Aldo_ket_red PF00248.21 KEZ37095.1 - 4.7e-69 232.8 0.0 5.7e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABM PF03992.16 KEZ37096.1 - 0.0067 16.5 0.3 0.013 15.6 0.3 1.5 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 KEZ37096.1 - 0.077 13.3 0.0 0.086 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) SsgA PF04686.12 KEZ37097.1 - 1.8e-29 101.6 0.0 2.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA WD40 PF00400.32 KEZ37098.1 - 6.6e-40 134.4 18.8 2.4e-05 25.0 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase PF00069.25 KEZ37098.1 - 1.8e-34 119.3 0.0 2.5e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ37098.1 - 6.8e-22 78.0 0.0 9.4e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KEZ37098.1 - 4.2e-21 75.1 0.0 0.0059 16.9 0.0 6.4 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ37098.1 - 2.2e-11 43.3 0.0 0.077 11.9 0.0 5.8 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein APH PF01636.23 KEZ37098.1 - 4.2e-06 26.9 0.2 0.0036 17.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Nbas_N PF15492.6 KEZ37098.1 - 0.00059 19.3 0.5 4.4 6.6 0.0 4.0 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Pkinase_fungal PF17667.1 KEZ37098.1 - 0.01 14.6 0.3 0.054 12.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF2415 PF10313.9 KEZ37098.1 - 0.013 15.5 0.0 0.053 13.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) RIO1 PF01163.22 KEZ37098.1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KEZ37098.1 - 0.095 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IKI3 PF04762.12 KEZ37098.1 - 0.22 9.4 0.1 4.4 5.2 0.0 2.0 1 1 1 2 2 2 0 IKI3 family SPX PF03105.19 KEZ37098.1 - 0.27 11.1 3.2 0.44 10.4 3.2 1.3 1 0 0 1 1 1 0 SPX domain LEA_2 PF03168.13 KEZ37101.1 - 0.092 13.3 0.3 0.8 10.3 0.1 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein Cupredoxin_1 PF13473.6 KEZ37102.1 - 0.00016 21.7 0.0 0.00036 20.6 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 KEZ37102.1 - 0.0019 18.6 0.0 0.0035 17.8 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF3466 PF11949.8 KEZ37103.1 - 0.13 10.9 8.9 1.4 7.4 0.1 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3466) ECH_1 PF00378.20 KEZ37104.1 - 5.8e-51 173.2 0.0 6.5e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ37104.1 - 3.5e-29 102.4 0.3 6e-27 95.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase APH PF01636.23 KEZ37105.1 - 1.1e-27 97.5 11.0 3.2e-27 96.0 11.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ37105.1 - 0.0034 17.0 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEZ37105.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase VirB8 PF04335.13 KEZ37106.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 VirB8 protein Helicase_C_3 PF13625.6 KEZ37108.1 - 3.1e-30 104.9 1.7 1.1e-29 103.2 1.7 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WYL PF13280.6 KEZ37108.1 - 0.0014 18.7 0.1 0.0043 17.1 0.1 1.9 2 0 0 2 2 2 1 WYL domain SnoaL PF07366.12 KEZ37109.1 - 3.2e-21 75.5 0.0 3.8e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEZ37109.1 - 2.9e-19 69.6 0.5 3.4e-19 69.4 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 KEZ37109.1 - 1.6e-05 25.0 0.3 6.6e-05 23.0 0.3 1.8 1 1 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain DUF4440 PF14534.6 KEZ37109.1 - 0.002 18.5 0.3 0.0028 18.0 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Urate_ox_N PF06181.11 KEZ37110.1 - 0.037 13.4 0.2 0.08 12.3 0.0 1.6 2 0 0 2 2 2 0 Urate oxidase N-terminal DUF4684 PF15736.5 KEZ37110.1 - 4.3 5.9 6.9 5.2 5.6 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) DDE_Tnp_IS66_C PF13817.6 KEZ37111.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 IS66 C-terminal element DDE_Tnp_IS66 PF03050.14 KEZ37111.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Transposase IS66 family PIN PF01850.21 KEZ37114.1 - 3.2e-17 63.1 0.5 3.8e-17 62.9 0.5 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KEZ37114.1 - 0.0038 18.0 1.7 0.0053 17.5 1.7 1.3 1 0 0 1 1 1 1 PIN domain PIN_6 PF17146.4 KEZ37114.1 - 0.0059 17.1 0.1 0.016 15.7 0.1 1.7 1 1 0 1 1 1 1 PIN domain of ribonuclease PIN_9 PF18477.1 KEZ37114.1 - 0.0065 16.8 1.1 0.33 11.3 1.1 2.1 1 1 0 1 1 1 1 PIN like domain AAA_lid_4 PF17864.1 KEZ37114.1 - 0.071 12.9 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 RuvB AAA lid domain PIN_4 PF13638.6 KEZ37114.1 - 0.18 12.1 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 PIN domain Methyltransf_19 PF04672.12 KEZ37115.1 - 2.7e-53 181.2 0.1 3.3e-53 180.9 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase SnoaL PF07366.12 KEZ37116.1 - 1.3e-11 44.4 0.1 1.6e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KEZ37116.1 - 0.0023 18.5 1.5 0.0033 18.0 1.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain vATP-synt_AC39 PF01992.16 KEZ37116.1 - 0.097 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Abhydrolase_6 PF12697.7 KEZ37118.1 - 1.5e-23 84.6 11.8 1.9e-23 84.3 11.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ37118.1 - 2.6e-19 69.9 0.1 5.1e-15 55.8 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ37118.1 - 2.5e-18 66.2 0.0 6.6e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KEZ37118.1 - 8.5e-05 22.5 0.0 0.008 16.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase GerE PF00196.19 KEZ37119.1 - 1.5e-15 56.5 0.0 2.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ37119.1 - 8.6e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KEZ37119.1 - 0.00035 20.3 2.0 0.00072 19.3 0.2 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ37119.1 - 0.025 14.0 0.1 0.058 12.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KEZ37119.1 - 0.031 14.1 0.1 0.076 12.8 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KEZ37119.1 - 0.035 14.2 0.5 0.092 12.9 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ37119.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 AMP-binding PF00501.28 KEZ37120.1 - 4.2e-74 249.7 0.0 5e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ37120.1 - 5.7e-16 59.3 0.4 1.1e-15 58.4 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PsiB PF06290.11 KEZ37120.1 - 0.011 15.2 0.0 0.052 13.0 0.0 2.0 1 1 1 2 2 2 0 Plasmid SOS inhibition protein (PsiB) GerE PF00196.19 KEZ37121.1 - 4.7e-14 51.7 0.2 7.5e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family GAF_2 PF13185.6 KEZ37121.1 - 3.4e-06 27.4 2.1 3.9e-06 27.2 0.4 1.9 2 1 0 2 2 2 1 GAF domain Sigma70_r4 PF04545.16 KEZ37121.1 - 1.5e-05 24.4 0.1 7.6e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KEZ37121.1 - 0.00072 19.2 0.2 0.00072 19.2 0.2 2.5 3 0 0 3 3 3 1 Sigma-70, region 4 GAF PF01590.26 KEZ37121.1 - 0.0022 18.6 0.0 0.0049 17.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain HTH_24 PF13412.6 KEZ37121.1 - 0.0096 15.5 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KEZ37121.1 - 0.025 14.6 0.0 0.091 12.7 0.0 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_10 PF04967.12 KEZ37121.1 - 0.04 13.7 0.4 0.15 11.9 0.0 2.1 2 1 0 2 2 2 0 HTH DNA binding domain Sigma70_ECF PF07638.11 KEZ37121.1 - 0.056 13.3 0.9 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 ECF sigma factor Birna_RdRp PF04197.12 KEZ37121.1 - 0.073 11.4 0.1 0.095 11.0 0.1 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Phage_NinH PF06322.11 KEZ37121.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Phage NinH protein SsgA PF04686.12 KEZ37121.1 - 0.2 11.7 1.9 0.63 10.1 0.1 2.7 4 0 0 4 4 4 0 Streptomyces sporulation and cell division protein, SsgA DDE_Tnp_IS66 PF03050.14 KEZ37122.1 - 9.4e-39 133.6 0.0 1.2e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_ISAZ013 PF07592.11 KEZ37123.1 - 4.1e-06 26.0 0.0 5.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain Gp_dh_C PF02800.20 KEZ37124.1 - 8.4e-60 200.9 0.0 1.4e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KEZ37124.1 - 4.2e-35 120.1 0.0 8.9e-34 115.9 0.0 2.2 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ37124.1 - 0.006 17.1 0.2 0.047 14.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 KEZ37124.1 - 0.011 16.4 0.4 0.071 13.8 0.4 2.2 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ37124.1 - 0.022 14.1 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KEZ37124.1 - 0.033 14.2 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF4916 PF16262.5 KEZ37124.1 - 0.044 13.3 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) NAD_binding_7 PF13241.6 KEZ37124.1 - 0.093 13.2 0.1 1.1 9.7 0.1 2.4 1 1 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 KEZ37124.1 - 0.12 13.2 0.0 0.35 11.7 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pribosyltran PF00156.27 KEZ37127.1 - 3.1e-25 88.5 0.0 6.6e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Hydrolase_4 PF12146.8 KEZ37127.1 - 2.2e-07 30.4 0.1 0.014 14.7 0.1 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KEZ37127.1 - 7.3e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KEZ37127.1 - 0.00028 20.6 0.1 0.0028 17.3 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Usp PF00582.26 KEZ37127.1 - 0.0013 19.3 5.5 0.41 11.1 0.0 3.2 3 1 0 3 3 3 2 Universal stress protein family UPRTase PF14681.6 KEZ37127.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KEZ37127.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase ABC_tran PF00005.27 KEZ37128.1 - 1e-32 113.5 0.0 1.3e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ37128.1 - 9.1e-09 35.5 0.1 0.0035 17.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ37128.1 - 0.00013 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ37128.1 - 0.00027 20.9 0.1 0.00044 20.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 KEZ37128.1 - 0.00037 20.7 0.0 0.0038 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KEZ37128.1 - 0.00043 19.8 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ37128.1 - 0.00064 20.1 0.9 0.0012 19.2 0.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ37128.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KEZ37128.1 - 0.012 15.5 0.3 0.054 13.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KEZ37128.1 - 0.021 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 KEZ37128.1 - 0.025 14.9 0.0 0.043 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ37128.1 - 0.027 14.7 0.1 0.099 12.9 0.0 2.0 2 2 1 3 3 2 0 AAA domain SbcCD_C PF13558.6 KEZ37128.1 - 0.033 14.4 0.9 0.42 10.9 0.3 2.9 2 2 1 3 3 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 KEZ37128.1 - 0.034 13.5 0.1 0.075 12.4 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KEZ37128.1 - 0.042 13.6 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KEZ37128.1 - 0.06 13.4 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KEZ37128.1 - 0.089 13.3 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KEZ37128.1 - 0.099 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KEZ37128.1 - 0.12 12.9 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEZ37128.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 KEZ37128.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Dynamin family BPD_transp_1 PF00528.22 KEZ37129.1 - 1.8e-16 60.4 10.5 1.8e-16 60.4 10.5 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FeoB_C PF07664.12 KEZ37129.1 - 0.36 10.5 3.5 3.2 7.5 0.5 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus YbgT_YccB PF08173.11 KEZ37129.1 - 7.7 6.7 7.5 0.87 9.8 1.4 2.5 2 0 0 2 2 2 0 Membrane bound YbgT-like protein TOBE PF03459.17 KEZ37130.1 - 5e-11 42.7 0.8 7.3e-11 42.2 0.8 1.3 1 0 0 1 1 1 1 TOBE domain HTH_17 PF12728.7 KEZ37130.1 - 1e-08 35.2 0.1 3.7e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MerR PF00376.23 KEZ37130.1 - 1.3e-07 31.2 0.2 3e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR_1 PF13411.6 KEZ37130.1 - 1.5e-05 25.0 0.0 7.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 MerR HTH family regulatory protein HTH_Tnp_ISL3 PF13542.6 KEZ37130.1 - 0.00067 19.0 0.3 0.0027 17.1 0.1 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KEZ37130.1 - 0.0011 19.0 0.8 0.0023 17.9 0.0 2.1 3 1 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 KEZ37130.1 - 0.0012 18.6 0.1 0.0062 16.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain AbiEi_4 PF13338.6 KEZ37130.1 - 0.0026 17.9 0.3 0.0074 16.4 0.3 1.7 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin HTH_28 PF13518.6 KEZ37130.1 - 0.0026 17.8 0.1 0.0077 16.3 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 KEZ37130.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_8 PF02954.19 KEZ37130.1 - 0.017 14.9 0.4 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 KEZ37130.1 - 0.026 14.9 0.9 0.045 14.1 0.1 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain DUF3853 PF12964.7 KEZ37130.1 - 0.09 13.0 0.0 0.37 11.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3853) DUF746 PF05344.11 KEZ37130.1 - 0.12 12.2 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) NUDIX PF00293.28 KEZ37131.1 - 2.1e-09 37.5 0.0 2.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 KEZ37131.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) DNA_processg_A PF02481.15 KEZ37132.1 - 0.00078 18.8 0.0 0.00084 18.7 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A Pkinase PF00069.25 KEZ37133.1 - 0.00038 19.9 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TetR_C_1 PF02909.17 KEZ37134.1 - 1.5e-12 47.6 0.0 9.6e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ37134.1 - 3.4e-09 36.4 0.4 1.3e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 KEZ37134.1 - 0.05 13.4 0.0 0.24 11.2 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 KEZ37134.1 - 0.14 11.9 0.2 2.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain MFS_1 PF07690.16 KEZ37135.1 - 1.5e-52 178.7 55.5 3e-51 174.4 55.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KEZ37135.1 - 8.1 4.6 15.7 5.9 5.1 13.6 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) 4HBT_3 PF13622.6 KEZ37136.1 - 9.7e-20 71.9 2.7 9.7e-20 71.9 2.7 2.0 1 1 1 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KEZ37136.1 - 0.00013 21.8 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA thioesterase 4HBT PF03061.22 KEZ37136.1 - 0.099 13.0 0.1 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily Glyoxalase PF00903.25 KEZ37137.1 - 5.8e-07 29.8 0.1 7.2e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KEZ37137.1 - 0.00089 19.2 0.0 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KEZ37137.1 - 0.0043 17.8 0.0 0.0054 17.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyco_hydro_43 PF04616.14 KEZ37139.1 - 4.4e-18 65.6 0.0 5.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sulfate_transp PF00916.20 KEZ37140.1 - 4.3e-45 154.1 21.6 3.5e-27 95.2 0.3 2.3 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 KEZ37140.1 - 9.7e-10 38.1 0.0 1.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KEZ37140.1 - 1.5e-06 28.4 1.3 1.5e-06 28.4 1.3 2.3 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KEZ37140.1 - 2e-05 25.0 4.6 2e-05 25.0 4.6 3.7 3 1 1 4 4 4 3 Molybdate transporter of MFS superfamily DUF543 PF04418.12 KEZ37140.1 - 0.025 14.6 0.3 0.096 12.7 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF543) QCR10 PF09796.9 KEZ37140.1 - 0.14 12.3 0.3 0.14 12.3 0.3 4.5 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TMEM223 PF14640.6 KEZ37140.1 - 0.5 10.5 1.3 3.1 7.9 0.2 2.4 1 1 1 2 2 2 0 Transmembrane protein 223 DUF305 PF03713.13 KEZ37141.1 - 2.7e-49 167.2 15.1 6.7e-49 165.9 15.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 KEZ37141.1 - 3.9e-06 27.1 2.6 0.00083 19.6 0.6 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4142) TPPK_C PF12555.8 KEZ37141.1 - 0.27 11.3 3.0 0.58 10.3 3.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal FHA PF00498.26 KEZ37142.1 - 2.8e-07 30.8 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEZ37142.1 - 0.022 15.0 0.0 0.059 13.7 0.0 1.8 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Glyco_hydro_15 PF00723.21 KEZ37143.1 - 4e-55 187.4 0.0 8.9e-53 179.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Haem_degrading PF03928.14 KEZ37144.1 - 0.097 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Haem-degrading DUF2303 PF10065.9 KEZ37145.1 - 0.029 13.5 0.0 0.031 13.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) PMT_4TMC PF16192.5 KEZ37146.1 - 1.6e-24 86.7 18.3 1.9e-23 83.1 10.3 3.9 3 1 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 KEZ37146.1 - 3e-14 53.2 1.2 3e-14 53.2 1.2 3.8 3 2 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase TP_methylase PF00590.20 KEZ37147.1 - 1e-31 110.5 4.2 1.4e-31 110.1 4.2 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF218 PF02698.17 KEZ37148.1 - 0.0004 20.4 0.1 0.0059 16.6 0.1 2.0 1 1 0 1 1 1 1 DUF218 domain Peripla_BP_6 PF13458.6 KEZ37149.1 - 1.1e-26 94.3 16.4 1.5e-26 93.9 16.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein DUF108 PF01958.18 KEZ37149.1 - 0.079 13.3 1.2 0.18 12.2 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF108 TatD_DNase PF01026.21 KEZ37150.1 - 5.9e-69 232.3 0.0 6.8e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase RrnaAD PF00398.20 KEZ37151.1 - 2.8e-32 111.9 0.0 3.3e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KEZ37151.1 - 0.24 11.1 0.0 0.32 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA-synt_1b PF00579.25 KEZ37152.1 - 1.7e-52 178.6 0.0 2e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pribosyltran_N PF13793.6 KEZ37153.1 - 2.2e-42 143.6 0.0 1.1e-40 138.2 0.0 2.6 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEZ37153.1 - 1.7e-28 99.9 0.2 2.6e-26 92.8 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEZ37153.1 - 3.3e-18 65.7 1.1 2e-17 63.2 0.3 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ37153.1 - 0.0086 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Hexapep PF00132.24 KEZ37154.1 - 1.5e-21 75.3 4.9 8.1e-08 31.7 0.3 5.5 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KEZ37154.1 - 1.8e-21 76.8 0.0 2.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ37154.1 - 5e-20 72.5 14.4 5e-20 72.5 14.4 2.7 2 1 0 3 3 3 1 MobA-like NTP transferase domain IspD PF01128.19 KEZ37154.1 - 5.1e-10 39.5 10.1 9.7e-10 38.6 10.1 1.6 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 KEZ37154.1 - 3.5e-06 26.7 4.0 0.00049 19.8 0.2 4.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 KEZ37154.1 - 0.00024 21.1 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase DUF2064 PF09837.9 KEZ37154.1 - 0.3 10.9 4.4 0.17 11.7 1.9 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) FA_desaturase PF00487.24 KEZ37155.1 - 2.4e-18 66.9 20.0 2.4e-18 66.9 20.0 2.0 1 1 1 2 2 2 2 Fatty acid desaturase ABC_tran PF00005.27 KEZ37156.1 - 3.2e-52 176.7 0.0 4e-26 92.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEZ37156.1 - 2.2e-15 57.3 7.4 0.00082 19.3 0.1 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KEZ37156.1 - 1.6e-08 34.4 0.0 5.4e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 KEZ37156.1 - 2.8e-07 30.2 0.4 1.5 8.2 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ37156.1 - 1.8e-06 28.5 17.0 2.7e-05 24.6 1.1 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KEZ37156.1 - 1.9e-05 25.0 0.5 0.0045 17.3 0.1 3.3 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KEZ37156.1 - 2.5e-05 24.3 0.6 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KEZ37156.1 - 3.4e-05 24.4 0.0 0.059 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KEZ37156.1 - 6.1e-05 22.7 0.2 0.048 13.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MeaB PF03308.16 KEZ37156.1 - 0.00016 20.8 2.8 0.038 13.0 0.2 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran_CTD PF16326.5 KEZ37156.1 - 0.0006 20.0 8.3 0.0006 20.0 8.3 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain AAA_30 PF13604.6 KEZ37156.1 - 0.0013 18.5 9.3 0.072 12.8 0.5 3.2 4 1 0 4 4 4 2 AAA domain NACHT PF05729.12 KEZ37156.1 - 0.0016 18.4 0.2 1.2 9.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KEZ37156.1 - 0.0017 18.3 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 KEZ37156.1 - 0.0043 16.4 0.6 1.7 7.9 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 KEZ37156.1 - 0.0044 17.2 0.8 17 5.7 0.4 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KEZ37156.1 - 0.0079 15.8 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEZ37156.1 - 0.029 14.5 3.5 0.17 12.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain DUF3584 PF12128.8 KEZ37156.1 - 0.034 11.7 0.2 0.034 11.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) TsaE PF02367.17 KEZ37156.1 - 0.035 14.1 0.1 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KEZ37156.1 - 0.036 14.5 0.1 6.7 7.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KEZ37156.1 - 0.058 13.1 0.2 10 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 KEZ37156.1 - 0.079 12.9 0.1 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 KEZ37156.1 - 0.079 13.2 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PIF1 PF05970.14 KEZ37156.1 - 0.094 11.9 0.0 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase SRP54 PF00448.22 KEZ37156.1 - 0.2 11.3 0.8 0.71 9.5 0.1 2.2 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KEZ37156.1 - 0.39 9.3 1.0 6.7 5.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KEZ37156.1 - 0.43 10.8 3.4 4 7.7 0.1 3.6 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 KEZ37156.1 - 0.62 9.5 1.6 2.5 7.5 0.1 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_18 PF13238.6 KEZ37156.1 - 0.89 10.1 3.4 3.6 8.1 0.0 3.0 4 0 0 4 4 2 0 AAA domain DUF87 PF01935.17 KEZ37156.1 - 1.4 9.0 2.8 6.8 6.7 0.1 2.5 3 0 0 3 3 2 0 Helicase HerA, central domain GHMP_kinases_C PF08544.13 KEZ37157.1 - 2e-08 34.5 1.1 4.2e-08 33.4 1.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KEZ37157.1 - 5.2e-06 26.6 1.0 2.7e-05 24.3 1.0 2.3 1 0 0 1 1 1 1 GHMP kinases N terminal domain Asp23 PF03780.13 KEZ37158.1 - 3.8e-30 104.5 2.9 4.6e-30 104.2 2.9 1.1 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function DUF2273 PF10031.9 KEZ37160.1 - 2.9e-07 30.4 9.0 4.1e-07 29.9 9.0 1.2 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) DUF3040 PF11239.8 KEZ37160.1 - 0.13 12.5 2.8 0.19 12.0 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Asp23 PF03780.13 KEZ37161.1 - 4.3e-11 43.2 0.0 5e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function CT47 PF15623.6 KEZ37161.1 - 0.0024 17.8 0.2 0.0024 17.8 0.2 1.1 1 0 0 1 1 1 1 Cancer/testis gene family 47 Ribosomal_L25p PF01386.19 KEZ37164.1 - 2.5e-25 88.8 0.0 5.5e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 KEZ37164.1 - 1.4e-17 63.8 1.1 3e-17 62.7 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Pept_tRNA_hydro PF01195.19 KEZ37165.1 - 1.6e-55 187.7 0.0 1.8e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PIG-L PF02585.17 KEZ37166.1 - 8.1e-14 52.4 0.4 3.3e-13 50.4 0.4 1.9 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_trans_1_4 PF13692.6 KEZ37167.1 - 4.5e-25 88.6 0.0 8.5e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ37167.1 - 5.8e-11 42.6 0.0 3.6e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ37167.1 - 2e-05 25.1 6.2 2e-05 25.1 6.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KEZ37167.1 - 3.2e-05 23.5 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 KEZ37168.1 - 5.5e-21 75.5 0.1 8.1e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ37168.1 - 2.9e-16 59.7 0.0 4.3e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KEZ37168.1 - 9.1e-11 42.0 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KEZ37168.1 - 3.8e-08 33.0 0.0 8.9e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 KEZ37168.1 - 0.00024 21.5 0.8 0.00024 21.5 0.8 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Glyco_transf_21 PF13506.6 KEZ37169.1 - 1.2e-06 28.2 0.1 5.5e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEZ37169.1 - 2.9e-06 27.2 0.0 5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37169.1 - 0.00064 19.7 0.2 0.0029 17.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ37169.1 - 0.058 13.3 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 tRNA-synt_1b PF00579.25 KEZ37170.1 - 1.9e-63 214.5 0.0 2.4e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 KEZ37170.1 - 0.027 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain Peptidase_S8 PF00082.22 KEZ37171.1 - 1.6e-32 113.0 2.9 2.6e-32 112.3 2.9 1.3 1 0 0 1 1 1 1 Subtilase family NIF PF03031.18 KEZ37173.1 - 0.0038 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 KEZ37173.1 - 0.033 14.0 0.1 0.83 9.5 0.1 2.6 1 1 0 1 1 1 0 Acid Phosphatase Acetyltransf_7 PF13508.7 KEZ37173.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HAD_2 PF13419.6 KEZ37173.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ37173.1 - 0.76 10.0 3.6 2 8.7 0.4 3.0 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase PP-binding PF00550.25 KEZ37174.1 - 2.7e-06 27.6 0.3 3.3e-06 27.4 0.3 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KEZ37174.1 - 0.0066 16.6 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 Acyl-carrier Hexapep PF00132.24 KEZ37175.1 - 5.3e-12 45.0 2.4 5.8e-05 22.6 0.2 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ37175.1 - 0.00016 21.3 2.2 0.21 11.4 0.1 3.4 2 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Epimerase PF01370.21 KEZ37176.1 - 2.6e-38 131.9 0.0 3.2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ37176.1 - 3.7e-18 66.0 0.1 1.4e-17 64.1 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEZ37176.1 - 6.8e-12 45.1 0.0 8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEZ37176.1 - 1.7e-08 33.8 0.0 3.6e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEZ37176.1 - 8.5e-05 22.5 0.0 0.00044 20.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEZ37176.1 - 0.00027 20.2 0.2 0.0069 15.5 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KEZ37176.1 - 0.0055 15.9 0.3 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KEZ37176.1 - 0.031 13.8 0.0 0.34 10.4 0.0 2.2 2 1 0 2 2 2 0 NmrA-like family KR PF08659.10 KEZ37176.1 - 0.04 13.8 0.7 5.3 6.9 0.0 2.9 3 0 0 3 3 3 0 KR domain dTDP_sugar_isom PF00908.17 KEZ37177.1 - 2.5e-55 186.7 0.0 2.9e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Methyltransf_14 PF08484.11 KEZ37178.1 - 1.8e-57 193.6 0.0 2.5e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 KEZ37178.1 - 9e-20 70.7 0.1 1.6e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 KEZ37178.1 - 7e-12 45.5 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37178.1 - 9.3e-07 29.5 0.0 2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ37178.1 - 1.9e-05 25.2 0.0 5.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37178.1 - 0.00051 20.7 0.1 0.0017 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ37178.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Wzz PF02706.15 KEZ37180.1 - 3.2e-07 30.6 1.8 3.2e-07 30.6 1.8 2.1 3 0 0 3 3 3 1 Chain length determinant protein AdoHcyase PF05221.17 KEZ37180.1 - 0.11 11.6 0.1 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase adh_short PF00106.25 KEZ37182.1 - 9.3e-39 132.9 0.3 1.1e-38 132.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ37182.1 - 4.8e-27 95.0 2.0 6e-27 94.7 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ37182.1 - 1.7e-10 41.1 1.6 2.5e-10 40.6 1.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ37182.1 - 1.3e-05 24.8 0.2 2e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KEZ37182.1 - 8.3e-05 22.1 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KEZ37182.1 - 0.028 13.8 0.1 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PhyH PF05721.13 KEZ37183.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KEZ37183.1 - 0.0075 16.7 0.3 0.017 15.5 0.1 1.7 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase DUF4336 PF14234.6 KEZ37183.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) IspD PF01128.19 KEZ37184.1 - 2.7e-34 118.8 0.4 4.7e-34 118.1 0.4 1.4 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 KEZ37184.1 - 5.3e-19 69.1 9.8 1.1e-18 68.1 9.2 1.8 1 1 1 2 2 2 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 KEZ37184.1 - 0.22 11.4 0.0 0.45 10.4 0.0 1.5 2 0 0 2 2 2 0 Cytidylyltransferase DUF4910 PF16254.5 KEZ37185.1 - 3.7e-103 343.7 0.0 4.3e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4910) DUF2172 PF09940.9 KEZ37185.1 - 4.7e-35 119.9 0.0 7.1e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2172) HTH_47 PF16221.5 KEZ37185.1 - 1e-30 105.1 0.0 1.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 winged helix-turn-helix Peptidase_M28 PF04389.17 KEZ37185.1 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF4245 PF14030.6 KEZ37185.1 - 0.06 13.3 0.3 0.95 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) NTP_transferase PF00483.23 KEZ37186.1 - 3.8e-16 59.4 0.0 1.6e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ37186.1 - 4e-08 33.8 0.0 5.6e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Ntox30 PF15532.6 KEZ37187.1 - 0.17 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 30 Glyco_hydro_26 PF02156.15 KEZ37188.1 - 1.4e-08 34.6 0.1 2.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 MazG PF03819.17 KEZ37189.1 - 2.5e-27 94.9 0.2 7.1e-25 87.0 0.0 2.3 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 KEZ37189.1 - 0.00054 20.3 0.1 0.026 15.0 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase SurA_N_3 PF13624.6 KEZ37190.1 - 1.1e-07 31.7 0.1 1.7e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 SurA N-terminal domain SurA_N_2 PF13623.6 KEZ37190.1 - 4.3e-05 23.4 0.1 6.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 SurA N-terminal domain CarD_CdnL_TRCF PF02559.16 KEZ37191.1 - 2.6e-30 105.0 0.0 5.4e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 KEZ37191.1 - 3.6e-26 91.4 0.0 8.9e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 TRCF domain UvrB_inter PF17757.1 KEZ37191.1 - 7.2e-18 64.5 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 KEZ37191.1 - 1e-15 58.0 0.1 2.1e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ37191.1 - 7.1e-13 48.9 0.1 3.3e-12 46.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ37191.1 - 1.4e-06 28.5 0.0 5.5e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AroM PF07302.11 KEZ37191.1 - 0.04 13.3 0.1 0.088 12.2 0.1 1.5 1 0 0 1 1 1 0 AroM protein Glyco_tran_WecB PF03808.13 KEZ37191.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family AAA_22 PF13401.6 KEZ37191.1 - 0.12 12.6 0.1 0.67 10.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KEZ37191.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MerR_1 PF13411.6 KEZ37192.1 - 2.6e-18 65.9 0.0 4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ37192.1 - 4.8e-12 45.4 0.4 8.9e-12 44.6 0.4 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KEZ37192.1 - 8e-10 39.1 2.5 2.8e-09 37.4 2.5 1.9 1 1 0 1 1 1 1 MerR, DNA binding HTH_17 PF12728.7 KEZ37192.1 - 0.0055 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain EutB PF06751.11 KEZ37192.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Peptidase_S49 PF01343.18 KEZ37193.1 - 7.4e-72 240.3 0.0 9.5e-44 149.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 KEZ37193.1 - 0.097 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Enolase_C PF00113.22 KEZ37194.1 - 2.5e-130 434.1 0.0 3.1e-130 433.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KEZ37194.1 - 2.8e-55 186.1 0.0 5.3e-55 185.1 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KEZ37194.1 - 6.6e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KEZ37194.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DivIC PF04977.15 KEZ37195.1 - 1.6e-15 56.6 0.2 2e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Septum formation initiator RskA PF10099.9 KEZ37195.1 - 0.00091 19.6 0.4 0.0011 19.3 0.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_S21 PF01165.20 KEZ37195.1 - 0.03 14.1 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S21 V_ATPase_I PF01496.19 KEZ37195.1 - 0.12 10.3 0.0 0.13 10.1 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PrgH PF09480.10 KEZ37195.1 - 0.14 11.5 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF501 PF04417.12 KEZ37196.1 - 4.4e-33 114.1 0.1 1.3e-31 109.2 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF501) Ppx-GppA PF02541.16 KEZ37197.1 - 2.4e-57 194.6 0.1 5.4e-28 98.2 0.0 2.0 2 0 0 2 2 2 2 Ppx/GppA phosphatase family FtsA PF14450.6 KEZ37197.1 - 0.00055 20.3 1.6 0.17 12.3 0.2 2.5 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_N PF00370.21 KEZ37197.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain UDG PF03167.19 KEZ37198.1 - 1e-25 90.6 0.0 1.3e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pyr_redox_2 PF07992.14 KEZ37199.1 - 7.1e-38 130.5 0.0 9.4e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ37199.1 - 2.5e-07 31.1 0.0 2.3e-06 28.1 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase BaxI_1 PF12811.7 KEZ37200.1 - 5.5e-69 232.3 1.3 6e-69 232.1 1.3 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like CrgA PF06781.12 KEZ37200.1 - 0.23 11.5 1.2 0.74 9.9 0.1 2.4 2 1 0 2 2 2 0 Cell division protein CrgA Putative_PNPOx PF01243.20 KEZ37201.1 - 8.6e-14 51.5 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KEZ37201.1 - 1.1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like DUF4287 PF14117.6 KEZ37202.1 - 3.6e-23 81.5 0.1 4.1e-23 81.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4287) DUF459 PF04311.13 KEZ37204.1 - 2.1e-20 73.0 0.0 2.9e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF459) Lipase_GDSL_2 PF13472.6 KEZ37204.1 - 1.6e-07 31.9 1.1 2.8e-07 31.1 1.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MBOAT PF03062.19 KEZ37205.1 - 3.6e-29 102.2 0.6 5.8e-29 101.5 0.6 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KEZ37205.1 - 4.2e-08 33.4 0.4 1.1e-07 32.0 0.3 1.8 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4040 PF13244.6 KEZ37205.1 - 1.7 8.8 10.0 0.053 13.7 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Abhydrolase_1 PF00561.20 KEZ37206.1 - 1.9e-22 80.2 0.0 5.2e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ37206.1 - 2.1e-12 48.1 13.1 2.9e-12 47.7 13.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ37206.1 - 2.7e-10 39.9 0.1 2.7e-09 36.6 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KEZ37206.1 - 0.00027 21.0 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 KEZ37206.1 - 0.0062 16.4 0.6 0.05 13.4 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KEZ37206.1 - 0.014 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 KEZ37206.1 - 0.043 12.5 0.0 0.065 11.9 0.0 1.3 1 1 0 1 1 1 0 Ndr family Esterase_phd PF10503.9 KEZ37206.1 - 0.075 12.5 0.6 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ37206.1 - 0.21 11.0 0.1 6.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family MDMPI_C PF07398.11 KEZ37206.1 - 2.9 8.8 9.4 0.9 10.4 4.3 3.0 2 1 0 2 2 2 0 MDMPI C-terminal domain Trypsin PF00089.26 KEZ37208.1 - 0.031 14.1 2.7 0.09 12.6 0.1 2.1 2 0 0 2 2 2 0 Trypsin Trypsin_2 PF13365.6 KEZ37208.1 - 0.034 15.0 1.2 0.034 15.0 1.2 2.8 2 2 0 2 2 2 0 Trypsin-like peptidase domain PadR PF03551.14 KEZ37209.1 - 2.9e-11 43.1 0.0 5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 KEZ37209.1 - 5.7e-07 30.1 0.3 1.1e-06 29.2 0.3 1.5 1 0 0 1 1 1 1 Virulence activator alpha C-term HTH_27 PF13463.6 KEZ37209.1 - 0.006 17.1 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 KEZ37209.1 - 0.19 11.9 0.0 0.41 10.9 0.0 1.6 1 1 0 1 1 1 0 Winged helix DNA-binding domain VWA_2 PF13519.6 KEZ37210.1 - 8.1e-07 29.7 0.0 1.5e-05 25.6 0.0 2.9 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF4853 PF16145.5 KEZ37210.1 - 0.026 14.7 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) HEM4 PF02602.15 KEZ37210.1 - 0.16 11.3 1.4 0.24 10.7 0.1 1.9 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD VWA PF00092.28 KEZ37210.1 - 0.26 11.5 0.0 2.9 8.1 0.0 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Mg_chelatase PF01078.21 KEZ37211.1 - 4.7e-05 22.9 0.0 0.067 12.6 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ37211.1 - 4.8e-05 23.1 0.0 0.0084 15.8 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 KEZ37211.1 - 0.00017 21.6 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ37211.1 - 0.0017 18.8 0.7 0.0054 17.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 KEZ37211.1 - 0.0027 16.7 0.0 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_3 PF07726.11 KEZ37211.1 - 0.026 14.4 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEZ37211.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KEZ37211.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ37211.1 - 0.2 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GreA_GreB_N PF03449.15 KEZ37212.1 - 8.3e-27 93.1 1.6 1.1e-26 92.8 1.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 KEZ37212.1 - 3.7e-14 52.4 0.0 5.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term PIG-L PF02585.17 KEZ37213.1 - 2.7e-27 96.0 0.0 4.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase tRNA-synt_1_2 PF13603.6 KEZ37215.1 - 1e-41 142.5 0.0 8.3e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 KEZ37215.1 - 1.7e-31 109.2 0.5 1e-07 30.6 0.2 6.2 4 2 1 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEZ37215.1 - 8.7e-18 64.2 0.0 1.1e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEZ37215.1 - 1.2e-13 51.3 0.0 2.4e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEZ37215.1 - 0.053 12.9 0.0 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Thioredox_DsbH PF03190.15 KEZ37216.1 - 3.5e-71 238.4 0.0 4.9e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KEZ37216.1 - 5.5e-09 36.1 0.0 1.7e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 KEZ37216.1 - 0.035 13.4 0.1 0.81 8.9 0.0 2.4 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF3742 PF12553.8 KEZ37217.1 - 0.0022 18.1 0.5 0.051 13.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3742) HlyIII PF03006.20 KEZ37218.1 - 1.1e-35 123.4 16.3 1.2e-35 123.3 16.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related PEPCK_GTP PF00821.18 KEZ37219.1 - 1.1e-169 564.0 0.0 1.3e-169 563.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KEZ37219.1 - 1.1e-103 345.5 0.0 1.5e-103 345.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PhoH PF02562.16 KEZ37221.1 - 2.1e-53 180.8 0.0 2.8e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 KEZ37221.1 - 3.1e-26 92.2 0.0 5.4e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 KEZ37221.1 - 8.3e-07 28.9 0.1 1.7e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ37221.1 - 0.023 15.0 0.4 0.2 11.9 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ37221.1 - 0.026 14.9 0.4 0.06 13.7 0.4 1.6 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KEZ37221.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PMSR PF01625.21 KEZ37222.1 - 1.4e-64 216.9 0.3 1.6e-64 216.7 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Mu-like_Com PF10122.9 KEZ37224.1 - 0.038 13.4 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com DUF1356 PF07092.12 KEZ37224.1 - 0.051 12.8 0.1 0.051 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) PCMT PF01135.19 KEZ37225.1 - 0.0017 18.1 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Hydrolase_like PF13242.6 KEZ37228.1 - 7.7e-22 77.2 0.0 2.1e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KEZ37228.1 - 1.6e-21 76.3 0.0 2.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ37228.1 - 3.2e-06 27.4 0.0 2.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ37228.1 - 2.8e-05 24.5 0.2 0.00043 20.6 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADK PF00406.22 KEZ37230.1 - 4.8e-39 133.9 0.0 5.7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEZ37230.1 - 4.1e-20 72.6 0.0 6.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KEZ37230.1 - 4.7e-10 39.3 1.4 1e-09 38.2 1.4 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KEZ37230.1 - 1.3e-05 25.7 0.2 4.3e-05 24.1 0.1 1.9 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KEZ37230.1 - 0.0045 16.7 0.1 3.9 7.1 0.0 2.7 3 0 0 3 3 3 2 Thymidylate kinase GFA PF04828.14 KEZ37230.1 - 0.0067 16.7 0.6 0.68 10.3 0.0 2.5 2 1 1 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KEZ37230.1 - 0.0095 15.9 0.2 0.017 15.2 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon dNK PF01712.19 KEZ37230.1 - 0.0098 15.8 0.0 3.2 7.6 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase SRP54 PF00448.22 KEZ37230.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Zn-ribbon_8 PF09723.10 KEZ37230.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 KEZ37230.1 - 0.19 11.7 1.2 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal DUF983 PF06170.12 KEZ37230.1 - 0.27 11.7 1.6 8.2 6.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF983) NUDIX PF00293.28 KEZ37232.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain HxlR PF01638.17 KEZ37233.1 - 1e-25 89.3 0.0 1.3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 KEZ37233.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 KEZ37233.1 - 0.0033 17.5 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation HTH_24 PF13412.6 KEZ37233.1 - 0.072 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.6 KEZ37233.1 - 0.17 11.9 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix Pyr_redox_2 PF07992.14 KEZ37234.1 - 3.2e-55 187.4 1.1 4e-55 187.1 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEZ37234.1 - 2.5e-25 88.8 0.1 3.2e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEZ37234.1 - 3.9e-23 81.8 3.7 6.8e-19 68.2 0.2 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ37234.1 - 4.4e-13 49.2 0.7 1.3e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ37234.1 - 4.8e-12 45.9 5.8 2.2e-11 43.8 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ37234.1 - 4.1e-09 35.6 7.1 0.00034 19.4 1.1 3.8 3 1 1 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 KEZ37234.1 - 3.3e-08 33.1 2.1 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KEZ37234.1 - 3.7e-08 33.5 2.1 0.00036 20.7 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ37234.1 - 6e-08 32.2 6.7 4.6e-06 26.0 1.4 2.7 3 1 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 KEZ37234.1 - 2.6e-07 30.6 11.1 0.033 13.8 1.3 3.9 3 1 1 4 4 4 3 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KEZ37234.1 - 2.3e-06 27.6 1.9 0.00046 20.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KEZ37234.1 - 3.4e-06 26.4 2.4 3.4e-06 26.4 2.4 4.2 5 0 0 5 5 5 1 FAD binding domain XdhC_C PF13478.6 KEZ37234.1 - 3.8e-06 27.4 0.1 0.066 13.7 0.0 2.5 2 0 0 2 2 2 2 XdhC Rossmann domain FAD_binding_3 PF01494.19 KEZ37234.1 - 5.7e-06 25.8 2.5 0.0067 15.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 KEZ37234.1 - 1.6e-05 24.2 0.1 3.9e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 KEZ37234.1 - 0.00023 20.8 0.3 0.041 13.5 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ37234.1 - 0.00038 19.9 0.4 0.016 14.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KEZ37234.1 - 0.00047 19.5 4.4 0.032 13.5 0.8 2.8 2 1 1 3 3 3 2 Thi4 family NAD_binding_7 PF13241.6 KEZ37234.1 - 0.00067 20.1 0.2 0.32 11.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding ThiF PF00899.21 KEZ37234.1 - 0.044 13.1 0.4 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.18 KEZ37234.1 - 0.05 13.9 1.4 0.69 10.2 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Glu_dehyd_C PF16912.5 KEZ37234.1 - 0.068 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 KEZ37234.1 - 0.087 12.5 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KEZ37234.1 - 0.11 12.5 5.8 0.51 10.3 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ37234.1 - 0.24 10.4 4.1 18 4.2 1.4 3.5 3 1 0 3 3 3 0 Lycopene cyclase protein adh_short PF00106.25 KEZ37234.1 - 0.26 10.7 1.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Trp_halogenase PF04820.14 KEZ37234.1 - 2.8 6.7 3.7 2.3 7.0 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lyase_1 PF00206.20 KEZ37235.1 - 6.1e-99 331.3 0.0 8.9e-99 330.8 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KEZ37235.1 - 9.3e-21 74.0 0.7 2.1e-20 72.8 0.7 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus LYTB PF02401.18 KEZ37236.1 - 3.5e-78 262.5 0.0 3.9e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 LytB protein DHDPS PF00701.22 KEZ37236.1 - 0.079 11.7 0.3 0.14 10.8 0.3 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Exonuc_VII_L PF02601.15 KEZ37237.1 - 1.4e-66 225.2 0.8 2e-57 195.1 1.5 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 KEZ37237.1 - 7.1e-13 48.6 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 KEZ37237.1 - 0.0002 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Exonuc_VII_S PF02609.16 KEZ37238.1 - 3.1e-14 52.7 0.2 4e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit DUF4245 PF14030.6 KEZ37240.1 - 1.7e-36 125.8 0.9 1.7e-36 125.8 0.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4245) FBPase_glpX PF03320.13 KEZ37241.1 - 5.3e-138 459.0 6.9 6.1e-138 458.9 6.9 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded FA_hydroxylase PF04116.13 KEZ37242.1 - 2e-18 67.0 0.4 2.8e-18 66.5 0.4 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Polysacc_deac_1 PF01522.21 KEZ37243.1 - 6.5e-15 55.1 0.0 9.7e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Melibiase_2_C PF17450.2 KEZ37243.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.6 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain OPA3 PF07047.12 KEZ37244.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) RmuC PF02646.16 KEZ37245.1 - 3e-88 295.7 0.0 6.5e-88 294.6 0.0 1.5 2 0 0 2 2 2 1 RmuC family Trimer_CC PF08954.11 KEZ37245.1 - 0.018 14.6 3.6 0.019 14.5 1.4 2.3 2 0 0 2 2 2 0 Trimerisation motif TelA PF05816.11 KEZ37245.1 - 0.04 13.0 2.6 0.067 12.3 2.6 1.4 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) TPR_MLP1_2 PF07926.12 KEZ37245.1 - 3.4 7.8 13.6 11 6.1 5.8 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2563 PF10817.8 KEZ37245.1 - 3.5 8.3 6.9 0.7 10.5 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2563) CLZ PF16526.5 KEZ37245.1 - 3.9 7.9 7.5 6.6 7.2 0.2 3.5 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YchF-GTPase_C PF06071.13 KEZ37246.1 - 7.7e-38 128.6 0.0 1.4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KEZ37246.1 - 3.3e-22 78.7 0.0 9.1e-22 77.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ37246.1 - 5.2e-08 32.6 0.0 8.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KEZ37246.1 - 0.00015 21.8 0.3 0.00076 19.5 0.3 2.1 1 1 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 KEZ37246.1 - 0.042 13.9 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KEZ37246.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phage_integrase PF00589.22 KEZ37247.1 - 2.2e-19 69.9 0.0 4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KEZ37247.1 - 0.051 13.9 0.5 0.13 12.6 0.4 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain AsmA_2 PF13502.6 KEZ37248.1 - 0.14 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 AsmA-like C-terminal region DDE_Tnp_4 PF13359.6 KEZ37249.1 - 3e-20 72.5 0.0 3.3e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ37249.1 - 6.2e-07 29.3 0.1 9.9e-07 28.6 0.1 1.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_assoc PF13808.6 KEZ37250.1 - 1.7e-20 72.8 0.0 5.1e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 KEZ37250.1 - 1.2e-15 57.7 0.2 1.6e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 KEZ37251.1 - 1.2e-06 28.3 0.5 1.5e-06 28.1 0.5 1.2 1 0 0 1 1 1 1 Transposase DDE domain adh_short PF00106.25 KEZ37253.1 - 1.2e-44 152.1 0.0 2.7e-44 151.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ37253.1 - 1.8e-34 119.3 0.2 2.5e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ37253.1 - 8.7e-09 35.5 0.1 1.5e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ37253.1 - 0.0013 18.2 0.4 0.0063 16.0 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEZ37253.1 - 0.054 13.8 0.3 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DNA_binding_1 PF01035.20 KEZ37254.1 - 4.3e-28 97.3 0.0 1.6e-27 95.4 0.0 1.8 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KEZ37254.1 - 1.1e-06 29.4 0.0 1.9e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Sigma70_r2 PF04542.14 KEZ37255.1 - 2.1e-14 53.1 0.4 7.6e-14 51.2 0.1 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ37255.1 - 1.8e-10 40.3 0.0 3.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ37255.1 - 6.9e-07 28.7 0.2 1.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KEZ37255.1 - 0.00012 22.0 0.0 0.00025 21.0 0.0 1.5 1 1 0 1 1 1 1 ECF sigma factor HTH_38 PF13936.6 KEZ37255.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DNA_binding_1 PF01035.20 KEZ37256.1 - 5.1e-16 58.6 0.8 1.3e-15 57.2 0.2 1.9 2 1 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KEZ37256.1 - 6.5e-05 23.7 0.0 0.0001 23.0 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain HTH_15 PF12324.8 KEZ37256.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DUF4096 PF13340.6 KEZ37258.1 - 1.9e-26 92.1 0.1 4.3e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 KEZ37258.1 - 1.5e-11 44.4 0.1 2.3e-11 43.8 0.1 1.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 KEZ37258.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DUF4096 PF13340.6 KEZ37259.1 - 3.1e-26 91.4 2.1 3.5e-26 91.2 0.1 2.1 3 0 0 3 3 3 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 KEZ37259.1 - 1.8e-13 50.6 1.3 7.5e-13 48.6 1.3 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KEZ37259.1 - 1e-11 45.1 0.6 1.9e-11 44.1 0.6 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 KEZ37259.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Polbeta PF18765.1 KEZ37260.1 - 1.5e-11 44.2 0.0 1.8e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KEZ37260.1 - 7.6e-11 42.2 0.0 8.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF86 PF01934.17 KEZ37261.1 - 1.7e-19 69.9 0.0 2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 WYL PF13280.6 KEZ37262.1 - 5.3e-06 26.6 0.1 1.4e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 WYL domain Helicase_C_3 PF13625.6 KEZ37262.1 - 1.7e-05 24.9 0.4 3.9e-05 23.8 0.4 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bac_luciferase PF00296.20 KEZ37262.1 - 0.015 14.7 0.8 0.015 14.7 0.8 1.6 2 0 0 2 2 2 0 Luciferase-like monooxygenase DDE_Tnp_IS66 PF03050.14 KEZ37263.1 - 9.8e-31 107.3 0.0 1.3e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_5 PF13546.6 KEZ37265.1 - 3.7e-24 85.5 1.6 4.7e-24 85.2 1.6 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CHAT PF12770.7 KEZ37266.1 - 6.2e-47 160.4 0.8 2e-46 158.7 0.8 1.9 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KEZ37266.1 - 1.1e-15 56.9 27.2 0.00085 19.1 0.0 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ37266.1 - 8e-09 35.7 25.4 0.014 15.6 3.4 9.3 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ37266.1 - 0.006 16.2 0.0 55 3.6 0.0 5.9 6 1 0 6 6 6 0 TPR repeat DUF4404 PF14357.6 KEZ37266.1 - 0.026 15.2 0.3 0.34 11.6 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) TPR_2 PF07719.17 KEZ37266.1 - 0.21 11.8 14.2 20 5.6 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 KEZ37266.1 - 6.7 6.9 7.6 3.3 7.8 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Bac_luciferase PF00296.20 KEZ37269.1 - 3.6e-48 164.6 0.2 5.5e-48 164.0 0.2 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase MerR_1 PF13411.6 KEZ37270.1 - 2.7e-18 65.8 0.1 8.1e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ37270.1 - 1.1e-15 57.1 6.0 1.2e-15 57.0 3.1 2.2 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KEZ37270.1 - 5.5e-09 36.4 0.0 1.1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 MerR, DNA binding Cytochrom_D1 PF02239.16 KEZ37271.1 - 3.2e-10 39.1 0.2 1.1e-05 24.2 0.0 3.8 1 1 2 4 4 4 2 Cytochrome D1 heme domain Lactonase PF10282.9 KEZ37271.1 - 2.4e-07 30.4 0.2 0.0013 18.0 0.0 3.7 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF4141 PF13605.6 KEZ37271.1 - 0.47 9.7 3.2 0.28 10.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) Polysacc_deac_1 PF01522.21 KEZ37272.1 - 2.8e-17 62.7 0.0 5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase TAT_signal PF10518.9 KEZ37272.1 - 0.0099 15.7 6.8 0.0099 15.7 6.8 4.1 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence Polysacc_deac_1 PF01522.21 KEZ37273.1 - 8.7e-24 83.8 0.1 1.1e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KEZ37273.1 - 0.0018 17.5 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro_38N PF01074.22 KEZ37273.1 - 0.009 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Lipase_GDSL_2 PF13472.6 KEZ37274.1 - 7e-21 75.4 1.0 1.3e-20 74.5 1.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ37274.1 - 3.3e-08 33.7 0.0 8.6e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PKD PF00801.20 KEZ37274.1 - 0.00018 21.3 1.2 0.00047 20.0 0.7 2.1 1 1 0 1 1 1 1 PKD domain Sigma70_r2 PF04542.14 KEZ37275.1 - 5.6e-14 51.7 0.3 5.6e-14 51.7 0.3 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ37275.1 - 1e-06 28.3 0.1 2.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 KEZ37275.1 - 5.6e-05 23.7 2.4 0.00018 22.1 1.2 2.4 2 1 0 2 2 2 1 SnoaL-like domain Sigma70_r4 PF04545.16 KEZ37275.1 - 0.0022 17.5 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 DUF4440 PF14534.6 KEZ37275.1 - 0.003 17.9 0.2 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KEZ37275.1 - 0.0077 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.6 KEZ37276.1 - 6.8e-42 143.4 0.1 8.3e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ37276.1 - 3.7e-11 43.0 0.0 5.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ37276.1 - 8.2e-09 35.4 0.2 1.4e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KEZ37276.1 - 1.7e-05 24.0 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEZ37276.1 - 7.1e-05 22.0 0.0 0.00046 19.4 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KEZ37276.1 - 0.02 14.4 1.4 0.061 12.8 0.1 2.2 3 0 0 3 3 3 0 short chain dehydrogenase TrkA_N PF02254.18 KEZ37276.1 - 0.044 14.1 0.1 0.076 13.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 KEZ37276.1 - 0.079 13.1 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KEZ37276.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Kelch_1 PF01344.25 KEZ37277.1 - 5.7e-31 105.8 10.3 4.9e-09 35.6 0.0 7.8 8 0 0 8 8 8 6 Kelch motif Kelch_6 PF13964.6 KEZ37277.1 - 2.7e-21 75.1 20.2 5.8e-06 26.4 0.1 8.5 6 2 2 8 8 8 6 Kelch motif Kelch_4 PF13418.6 KEZ37277.1 - 4.1e-16 58.7 24.1 0.00045 20.2 0.1 7.8 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KEZ37277.1 - 3.6e-14 52.1 8.7 0.34 10.9 0.0 7.8 7 1 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 KEZ37277.1 - 1.1e-12 47.6 5.1 0.00022 21.1 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KEZ37277.1 - 1.7e-10 40.9 37.6 0.0072 16.6 0.6 8.0 8 0 0 8 8 8 4 Galactose oxidase, central domain PQQ_3 PF13570.6 KEZ37277.1 - 0.097 13.2 24.3 4.9 7.8 0.8 7.1 6 1 0 6 6 6 0 PQQ-like domain PQQ PF01011.21 KEZ37277.1 - 0.33 11.0 10.9 4.4 7.4 0.1 5.3 5 0 0 5 5 5 0 PQQ enzyme repeat LPG_synthase_TM PF03706.13 KEZ37278.1 - 3.4e-37 128.6 48.2 4e-37 128.4 48.2 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Glycos_transf_1 PF00534.20 KEZ37279.1 - 8.4e-38 129.6 0.0 1.1e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ37279.1 - 4.8e-31 108.0 0.5 7.7e-31 107.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ37279.1 - 6.9e-10 39.2 1.7 6.9e-10 39.2 1.7 2.2 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ37279.1 - 1.1e-07 32.2 0.0 2.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 MDMPI_N PF11716.8 KEZ37280.1 - 0.024 15.3 0.9 0.024 15.3 0.9 2.2 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain SpoIIE PF07228.12 KEZ37282.1 - 1.4e-37 129.5 0.3 1.9e-37 129.1 0.3 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) SLATT_3 PF18184.1 KEZ37282.1 - 0.41 10.8 3.1 0.92 9.6 3.1 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Amidase PF01425.21 KEZ37283.1 - 1.8e-98 330.4 3.1 1.6e-96 324.1 3.1 2.6 1 1 0 1 1 1 1 Amidase Transgly_assoc PF04226.13 KEZ37285.1 - 1.3e-09 38.2 12.7 1.3e-09 38.2 12.7 2.2 2 0 0 2 2 2 1 Transglycosylase associated protein CRCB PF02537.15 KEZ37285.1 - 0.0059 16.9 4.3 0.009 16.3 4.3 1.4 1 1 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) ThrE PF06738.12 KEZ37285.1 - 0.077 12.4 2.8 0.096 12.0 2.8 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter SNARE_assoc PF09335.11 KEZ37285.1 - 0.46 11.0 10.4 0.75 10.3 5.3 2.2 1 1 1 2 2 2 0 SNARE associated Golgi protein UPF0126 PF03458.13 KEZ37285.1 - 0.61 10.0 9.1 0.85 9.5 9.1 1.2 1 0 0 1 1 1 0 UPF0126 domain DUF4235 PF14019.6 KEZ37285.1 - 1.1 9.3 5.1 23 5.1 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) MS_channel PF00924.18 KEZ37286.1 - 1.4e-23 83.5 2.1 1.6e-23 83.3 0.4 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel Acetyltransf_1 PF00583.25 KEZ37287.1 - 0.039 14.2 0.0 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pyridoxal_deC PF00282.19 KEZ37289.1 - 1.7e-77 260.7 0.0 2.2e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyoxalase_6 PF18029.1 KEZ37290.1 - 6.8e-20 71.9 7.5 1.3e-11 45.2 1.4 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 KEZ37290.1 - 1.5e-13 51.1 0.3 7.2e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ37290.1 - 0.0002 21.6 0.5 0.42 10.9 0.1 2.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BKACE PF05853.12 KEZ37290.1 - 0.05 12.9 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme Beta_elim_lyase PF01212.21 KEZ37291.1 - 6.7e-35 120.8 0.1 8.8e-35 120.4 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase MDMPI_N PF11716.8 KEZ37292.1 - 0.00029 21.6 0.7 0.00029 21.6 0.7 1.6 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain SBP_bac_5 PF00496.22 KEZ37293.1 - 7.6e-58 196.3 0.0 9.9e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KEZ37296.1 - 6.2e-20 71.7 2.8 8.1e-20 71.3 2.8 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component TM_helix PF05552.12 KEZ37296.1 - 0.16 11.9 3.9 2.4 8.2 0.6 2.7 2 0 0 2 2 2 0 Conserved TM helix ABC_tran PF00005.27 KEZ37297.1 - 7.6e-21 75.1 0.0 9.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KEZ37297.1 - 0.0017 18.0 0.1 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ37297.1 - 0.014 15.8 0.5 0.022 15.2 0.5 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEZ37297.1 - 0.032 14.5 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ37297.1 - 0.043 13.7 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 KEZ37297.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEZ37297.1 - 0.055 13.5 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KEZ37297.1 - 0.062 13.2 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KEZ37297.1 - 0.11 12.7 0.3 0.21 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ37297.1 - 0.11 12.9 0.1 0.16 12.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ37297.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KEZ37297.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KEZ37297.1 - 0.15 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KEZ37297.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DIOX_N PF14226.6 KEZ37298.1 - 2.5e-14 54.1 0.0 4.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ37298.1 - 6.7e-14 52.2 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ring_hydroxyl_A PF00848.19 KEZ37300.1 - 2.3e-30 106.1 0.1 3.5e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KEZ37300.1 - 1.6e-19 69.7 0.0 2.8e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DDE_3 PF13358.6 KEZ37301.1 - 3.6e-15 56.0 0.0 4.3e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Luciferase_cat PF10285.9 KEZ37301.1 - 0.046 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Luciferase catalytic domain Mrr_cat_2 PF13156.6 KEZ37303.1 - 0.0011 18.9 0.2 0.0013 18.6 0.2 1.2 1 0 0 1 1 1 1 Restriction endonuclease N6_Mtase PF02384.16 KEZ37304.1 - 1.9e-55 188.3 0.0 2.6e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 KEZ37304.1 - 9.8e-22 78.1 0.0 2.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 HsdM N-terminal domain MTS PF05175.14 KEZ37304.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methylase_S PF01420.19 KEZ37305.1 - 4.4e-15 56.3 0.0 3.2e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain DUF2630 PF10944.8 KEZ37305.1 - 1.6 9.2 5.1 4.3 7.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) SWI2_SNF2 PF18766.1 KEZ37306.1 - 2.6e-22 79.6 0.4 8.4e-22 77.9 0.4 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 KEZ37306.1 - 2.7e-12 47.1 0.0 5.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 KEZ37306.1 - 8.6e-12 45.4 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KEZ37306.1 - 0.14 11.7 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Biotin_lipoyl_2 PF13533.6 KEZ37307.1 - 7.5e-11 41.7 2.7 6.2e-09 35.6 0.1 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 KEZ37307.1 - 2.3e-10 41.1 4.5 5.6e-07 30.2 0.6 3.3 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 KEZ37307.1 - 5.6e-08 32.3 2.8 2.7e-05 23.5 0.9 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 KEZ37307.1 - 0.0013 18.5 0.1 1.6 8.7 0.0 2.8 2 0 0 2 2 2 2 Biotin-requiring enzyme RicinB_lectin_2 PF14200.6 KEZ37308.1 - 0.7 10.7 3.8 4.2 8.2 2.0 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like MacB_PCD PF12704.7 KEZ37309.1 - 6.9e-36 124.4 10.9 6.9e-36 124.4 10.9 1.8 3 0 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 KEZ37309.1 - 1.1e-09 38.6 1.8 1.1e-09 38.6 1.8 3.2 3 0 0 3 3 3 2 FtsX-like permease family Rgp1 PF08737.10 KEZ37309.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Rgp1 ABC_tran PF00005.27 KEZ37310.1 - 2.4e-28 99.4 0.0 3.7e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ37310.1 - 2e-07 31.2 0.3 0.019 14.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ37310.1 - 1.8e-06 27.6 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ37310.1 - 0.00045 19.9 0.1 0.00087 19.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ37310.1 - 0.0054 17.1 3.6 0.038 14.4 3.6 2.2 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KEZ37310.1 - 0.013 15.3 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 KEZ37310.1 - 0.036 14.6 0.0 0.054 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ37310.1 - 0.041 13.8 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF3987 PF13148.6 KEZ37310.1 - 0.084 11.9 0.1 0.54 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NACHT PF05729.12 KEZ37310.1 - 0.099 12.6 0.2 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KEZ37310.1 - 0.1 12.8 1.0 0.3 11.3 0.3 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KEZ37310.1 - 0.12 12.6 0.2 2.6 8.4 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KEZ37310.1 - 0.14 12.3 0.7 0.25 11.5 0.2 1.8 2 1 0 2 2 2 0 AAA domain Biotin_lipoyl_2 PF13533.6 KEZ37311.1 - 2e-11 43.6 2.1 5.5e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 KEZ37311.1 - 8.7e-10 38.2 2.0 1.4e-09 37.5 2.0 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KEZ37311.1 - 2.3e-07 31.5 4.0 0.031 15.0 0.2 4.3 4 0 0 4 4 4 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 KEZ37311.1 - 9.4e-06 25.4 0.2 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_2 PF12700.7 KEZ37311.1 - 0.021 13.6 0.0 4.7 5.8 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein PTS_EIIA_1 PF00358.20 KEZ37311.1 - 0.025 14.4 0.1 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF2967 PF11179.8 KEZ37313.1 - 0.099 10.7 0.2 0.13 10.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Lant_dehydr_C PF14028.6 KEZ37314.1 - 1.2e-25 90.7 3.6 4.9e-24 85.4 3.6 2.7 1 1 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term LANC_like PF05147.13 KEZ37315.1 - 5.1e-24 84.5 0.0 9.1e-24 83.7 0.0 1.4 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein TMF_DNA_bd PF12329.8 KEZ37316.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KEZ37316.1 - 0.037 13.8 0.2 0.052 13.3 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator CCDC106 PF15794.5 KEZ37316.1 - 0.087 12.5 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Glyco_hydro_26 PF02156.15 KEZ37317.1 - 3.2e-09 36.7 1.2 4.9e-09 36.0 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Cellulase PF00150.18 KEZ37317.1 - 0.0019 17.7 0.4 0.0025 17.3 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MLTR_LBD PF17765.1 KEZ37318.1 - 3.5e-25 89.1 7.2 3.5e-25 89.1 7.2 1.6 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KEZ37318.1 - 4.2e-17 62.2 3.3 4.2e-17 62.2 3.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ37318.1 - 3.2e-08 33.5 0.0 7.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ37318.1 - 0.021 14.8 0.0 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_25 PF13413.6 KEZ37318.1 - 0.037 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 KEZ37318.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain LA-virus_coat PF09220.10 KEZ37318.1 - 0.17 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 L-A virus, major coat protein FMN_red PF03358.15 KEZ37319.1 - 4.8e-39 133.6 0.1 7.5e-39 132.9 0.1 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEZ37319.1 - 2.1e-10 40.7 0.0 2.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KEZ37319.1 - 0.0022 18.2 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin domain MarR_2 PF12802.7 KEZ37320.1 - 8.5e-13 48.0 1.2 8.5e-13 48.0 1.2 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KEZ37320.1 - 1.7e-10 41.2 0.0 3.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 KEZ37320.1 - 2.4e-10 40.2 0.0 5.9e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 KEZ37320.1 - 8.7e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KEZ37320.1 - 0.00042 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 KEZ37320.1 - 0.0005 20.1 0.3 0.0013 18.7 0.2 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 KEZ37320.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_5 PF01022.20 KEZ37320.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_1 PF00126.27 KEZ37320.1 - 0.039 13.9 0.2 0.28 11.2 0.1 2.5 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 KEZ37320.1 - 0.054 13.1 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2927 PF11150.8 KEZ37320.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) HTH_IclR PF09339.10 KEZ37320.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.9 4 0 0 4 4 4 0 IclR helix-turn-helix domain Rrf2 PF02082.20 KEZ37320.1 - 0.16 12.4 0.0 0.41 11.0 0.0 1.7 1 1 0 1 1 1 0 Transcriptional regulator Phenol_Hydrox PF02332.18 KEZ37321.1 - 4.3e-73 245.6 0.1 6.7e-73 245.0 0.1 1.3 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase YHS PF04945.13 KEZ37321.1 - 3.6e-09 36.6 0.0 7.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 YHS domain TmoB PF06234.12 KEZ37322.1 - 1.6e-29 101.8 0.7 1.7e-29 101.7 0.7 1.0 1 0 0 1 1 1 1 Toluene-4-monooxygenase system protein B (TmoB) Rieske PF00355.26 KEZ37323.1 - 6e-14 51.8 0.0 8.4e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KEZ37323.1 - 2.2e-09 37.2 0.0 2.6e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MmoB_DmpM PF02406.17 KEZ37324.1 - 9e-24 83.5 0.0 1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 MmoB/DmpM family Phenol_Hydrox PF02332.18 KEZ37325.1 - 2.2e-64 217.2 3.2 3.2e-64 216.6 3.2 1.2 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase Pro_CA PF00484.19 KEZ37326.1 - 5.2e-12 46.3 0.0 1.6e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Carbonic anhydrase Tex_N PF09371.10 KEZ37327.1 - 1.9e-69 233.0 0.0 3.8e-69 232.0 0.0 1.5 2 0 0 2 2 2 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KEZ37327.1 - 4e-49 166.3 0.0 6.7e-49 165.5 0.0 1.4 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 KEZ37327.1 - 1.2e-26 92.7 0.0 2.4e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 KEZ37327.1 - 4.2e-23 82.0 0.0 1.2e-22 80.6 0.0 1.8 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 KEZ37327.1 - 2.1e-18 66.4 0.4 4.5e-18 65.4 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 KEZ37327.1 - 2.1e-08 34.5 0.0 4.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KEZ37327.1 - 4.6e-05 23.3 0.0 7.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 T2SSK PF03934.13 KEZ37327.1 - 0.002 17.6 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K ALIX_LYPXL_bnd PF13949.6 KEZ37327.1 - 0.094 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV HHH PF00633.23 KEZ37327.1 - 0.098 12.6 0.0 0.37 10.8 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_6 PF14579.6 KEZ37327.1 - 0.12 12.7 0.0 0.56 10.5 0.0 2.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNase_II_C_S1 PF18614.1 KEZ37327.1 - 0.29 11.1 6.8 0.73 9.8 0.2 3.1 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain MEDS PF14417.6 KEZ37328.1 - 7.9e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HATPase_c_2 PF13581.6 KEZ37328.1 - 4.4e-15 55.8 0.1 1e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Polyketide_cyc2 PF10604.9 KEZ37329.1 - 2.3e-12 47.4 2.5 2.9e-12 47.1 2.5 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3618 PF12277.8 KEZ37330.1 - 7.1e-16 58.2 1.8 7.1e-16 58.2 1.8 3.4 4 1 0 4 4 4 1 Protein of unknown function (DUF3618) Apolipoprotein PF01442.18 KEZ37330.1 - 4.7e-06 26.6 11.8 6.6e-06 26.1 11.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KEZ37330.1 - 0.00033 21.2 24.1 0.024 15.2 8.9 2.9 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Amnionless PF14828.6 KEZ37330.1 - 0.032 13.1 0.5 0.038 12.8 0.5 1.1 1 0 0 1 1 1 0 Amnionless DUF4164 PF13747.6 KEZ37330.1 - 0.048 13.9 0.4 0.048 13.9 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) OHCU_decarbox PF09349.10 KEZ37330.1 - 0.091 13.2 6.0 2.4 8.6 6.0 2.2 1 1 0 1 1 1 0 OHCU decarboxylase MHB PF16525.5 KEZ37330.1 - 0.21 11.8 4.9 0.44 10.8 3.8 2.1 1 1 1 2 2 2 0 Haemophore, haem-binding DUF2599 PF10783.9 KEZ37330.1 - 1.2 9.9 4.0 2.5 8.8 1.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2599) Phage_holin_3_6 PF07332.11 KEZ37331.1 - 1.1e-32 112.4 9.0 1.4e-32 112.1 9.0 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KEZ37331.1 - 0.0026 16.6 0.0 0.0031 16.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Collagen PF01391.18 KEZ37331.1 - 0.005 16.6 7.1 0.011 15.5 7.1 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3180 PF11377.8 KEZ37331.1 - 0.0075 16.4 4.7 0.013 15.6 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) HlyE PF06109.13 KEZ37331.1 - 0.2 11.0 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) DUF3099 PF11298.8 KEZ37331.1 - 0.39 10.9 4.9 0.69 10.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Abhydrolase_6 PF12697.7 KEZ37332.1 - 1.9e-20 74.4 9.3 2.7e-20 73.9 9.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ37332.1 - 6.6e-19 68.6 0.0 1.7e-18 67.2 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ37332.1 - 4.8e-17 62.0 0.1 7e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEZ37332.1 - 7.6e-07 29.5 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KEZ37332.1 - 1.9e-05 24.5 0.1 6.2e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 KEZ37332.1 - 0.0001 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 KEZ37332.1 - 0.00015 21.5 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF3141 PF11339.8 KEZ37332.1 - 0.0024 16.4 0.1 0.0035 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3141) Abhydrolase_2 PF02230.16 KEZ37332.1 - 0.015 15.1 0.1 0.084 12.7 0.0 2.1 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Ndr PF03096.14 KEZ37332.1 - 0.022 13.5 0.0 0.047 12.4 0.0 1.5 1 0 0 1 1 1 0 Ndr family LIDHydrolase PF10230.9 KEZ37332.1 - 0.092 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 KEZ37332.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DegT_DnrJ_EryC1 PF01041.17 KEZ37333.1 - 1.6e-99 333.6 0.2 1.8e-99 333.4 0.2 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEZ37333.1 - 0.00023 19.8 0.1 0.00032 19.3 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEZ37333.1 - 0.0039 16.4 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEZ37333.1 - 0.0068 15.7 0.3 0.0095 15.2 0.3 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Epimerase PF01370.21 KEZ37334.1 - 8.7e-51 172.7 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ37334.1 - 6.6e-41 140.8 0.0 7.5e-40 137.3 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ37334.1 - 4.3e-27 94.8 0.0 5.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEZ37334.1 - 3.8e-19 68.9 0.0 4.6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEZ37334.1 - 9.2e-18 64.3 0.0 8.9e-13 48.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEZ37334.1 - 7.8e-15 55.2 0.0 1.4e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEZ37334.1 - 6.6e-13 48.4 0.1 2.6e-08 33.3 0.3 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.13 KEZ37334.1 - 0.00013 21.6 0.1 0.0019 17.8 0.1 2.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KEZ37334.1 - 0.017 14.6 0.3 0.12 11.9 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase HTH_8 PF02954.19 KEZ37334.1 - 0.05 13.4 0.1 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family MGDG_synth PF06925.11 KEZ37335.1 - 3.6e-07 30.4 0.0 4.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 KEZ37335.1 - 0.00072 19.6 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 KEZ37335.1 - 0.041 14.3 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Mg_trans_NIPA PF05653.14 KEZ37336.1 - 1e-06 28.1 10.7 1.5e-06 27.6 10.7 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA TMEM234 PF10639.9 KEZ37336.1 - 0.0003 20.8 1.9 0.00044 20.3 0.5 2.0 3 0 0 3 3 3 1 Putative transmembrane family 234 EamA PF00892.20 KEZ37336.1 - 0.00051 20.2 7.4 0.00051 20.2 7.4 3.9 1 1 3 4 4 4 2 EamA-like transporter family VbhA PF18495.1 KEZ37337.1 - 0.00062 19.6 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Antitoxin VbhA zf-HC2 PF13490.6 KEZ37337.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 1 1 2 2 2 0 Putative zinc-finger UPF0175 PF03683.13 KEZ37337.1 - 0.025 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_psq PF05225.16 KEZ37337.1 - 0.07 12.9 0.2 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DUF397 PF04149.12 KEZ37338.1 - 3.2e-25 87.9 0.3 3.8e-25 87.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KEZ37339.1 - 1.2e-17 64.0 2.6 4e-17 62.3 2.6 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ37339.1 - 8.3e-06 25.8 0.0 2.6e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_25 PF13413.6 KEZ37339.1 - 0.00096 19.0 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ37339.1 - 0.0024 17.8 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KEZ37339.1 - 0.0046 16.9 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 KEZ37339.1 - 0.0058 16.8 0.1 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ37339.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KEZ37339.1 - 0.056 13.3 0.1 0.056 13.3 0.1 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Ferric_reduct PF01794.19 KEZ37341.1 - 7e-14 52.0 11.1 1.4e-13 51.0 11.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KEZ37341.1 - 4.4e-07 30.5 0.0 7.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEZ37341.1 - 0.0084 16.4 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FMN_bind PF04205.14 KEZ37342.1 - 3.5e-06 27.5 0.0 3.5e-06 27.5 0.0 1.9 2 1 0 2 2 2 1 FMN-binding domain PRR18 PF15671.5 KEZ37342.1 - 0.024 14.5 6.8 0.029 14.3 6.8 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 ApbE PF02424.15 KEZ37343.1 - 2e-37 129.1 0.0 5.6e-27 94.9 0.9 2.0 1 1 1 2 2 2 2 ApbE family Trans_reg_C PF00486.28 KEZ37344.1 - 1.3e-27 95.6 0.1 1.9e-26 91.9 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KEZ37344.1 - 1.5e-27 96.0 0.0 2.1e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KEZ37345.1 - 1.2e-24 87.0 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ37345.1 - 2.9e-18 65.7 2.0 7.5e-18 64.3 1.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ37345.1 - 6.9e-13 48.8 3.1 6.9e-13 48.8 3.1 2.5 2 0 0 2 2 2 1 HAMP domain MTS PF05175.14 KEZ37346.1 - 5.9e-12 45.4 0.0 3.4e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KEZ37346.1 - 1e-07 31.8 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37346.1 - 6.6e-07 30.0 0.1 3.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KEZ37346.1 - 2.2e-05 24.0 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 KEZ37346.1 - 0.00058 19.4 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 KEZ37346.1 - 0.0011 19.7 0.1 0.0043 17.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ37346.1 - 0.0011 19.5 0.1 0.02 15.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ37346.1 - 0.0021 17.9 0.0 0.02 14.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ37346.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 KEZ37346.1 - 0.019 14.3 0.0 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KEZ37346.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmC_N PF17827.1 KEZ37346.1 - 0.044 14.4 0.3 1.3 9.6 0.1 2.5 1 1 1 2 2 2 0 PrmC N-terminal domain Methyltransf_15 PF09445.10 KEZ37346.1 - 0.047 13.3 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Mur_ligase PF01225.25 KEZ37346.1 - 0.061 13.6 0.1 0.34 11.3 0.0 2.3 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Methyltransf_2 PF00891.18 KEZ37346.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Tyrosinase PF00264.20 KEZ37347.1 - 3.7e-40 138.6 0.0 4.7e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase TetR_C_1 PF02909.17 KEZ37350.1 - 1.9e-13 50.5 0.1 4.5e-12 46.0 0.1 2.2 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ37350.1 - 1.9e-09 37.2 0.1 4.8e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF4170 PF13773.6 KEZ37350.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) ABC_tran PF00005.27 KEZ37351.1 - 4.5e-22 79.0 0.0 5.6e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KEZ37351.1 - 0.00035 20.3 0.1 0.00072 19.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 KEZ37351.1 - 0.00038 20.1 0.1 0.00053 19.7 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KEZ37351.1 - 0.003 18.0 0.1 0.0044 17.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KEZ37351.1 - 0.0039 16.9 0.1 0.0084 15.8 0.1 1.5 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 KEZ37351.1 - 0.0045 16.8 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_23 PF13476.6 KEZ37351.1 - 0.0061 17.1 0.0 0.0086 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KEZ37351.1 - 0.021 14.7 0.1 0.031 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KEZ37351.1 - 0.03 14.3 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KEZ37351.1 - 0.034 14.6 0.2 0.058 13.8 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ37351.1 - 0.055 13.7 0.1 0.08 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ37351.1 - 0.06 12.9 1.2 0.069 12.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEZ37351.1 - 0.09 12.1 0.2 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KEZ37351.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MukB PF04310.12 KEZ37351.1 - 0.12 12.2 0.3 0.17 11.7 0.3 1.4 1 1 0 1 1 1 0 MukB N-terminal AAA_5 PF07728.14 KEZ37351.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KEZ37351.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 KEZ37351.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ37351.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 KEZ37351.1 - 0.19 11.3 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KEZ37351.1 - 0.2 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF5615 PF18480.1 KEZ37352.1 - 0.0095 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) HSP90 PF00183.18 KEZ37353.1 - 6.2e-134 447.7 0.0 1.5e-126 423.4 0.0 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 KEZ37353.1 - 1.7e-10 41.4 0.1 3.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEZ37353.1 - 1.7e-10 40.8 0.1 3.5e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma70_r2 PF04542.14 KEZ37354.1 - 8.1e-09 35.1 1.0 2.6e-08 33.5 1.0 2.0 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ37354.1 - 4.1e-08 32.8 0.1 1.1e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Imm35 PF15567.6 KEZ37354.1 - 0.021 15.0 0.3 0.073 13.2 0.3 1.9 1 0 0 1 1 1 0 Immunity protein 35 Sigma70_r4 PF04545.16 KEZ37354.1 - 0.029 13.9 0.3 0.084 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 TPR_7 PF13176.6 KEZ37354.1 - 0.16 12.1 3.5 0.33 11.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YCII PF03795.14 KEZ37355.1 - 4.3e-11 43.1 0.0 4.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain PSK_trans_fac PF07704.11 KEZ37356.1 - 2.2e-21 76.4 2.5 2.7e-21 76.1 2.5 1.0 1 0 0 1 1 1 1 Rv0623-like transcription factor DDE_Tnp_4 PF13359.6 KEZ37358.1 - 2.6e-12 46.7 0.0 4.7e-12 45.9 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ37358.1 - 0.0053 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Sigma70_r4 PF04545.16 KEZ37358.1 - 0.017 14.7 0.1 0.037 13.6 0.0 1.6 1 1 1 2 2 2 0 Sigma-70, region 4 ABC_tran PF00005.27 KEZ37359.1 - 1.5e-22 80.6 0.0 3.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ37359.1 - 0.00018 21.4 0.1 0.016 15.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ37359.1 - 0.00051 19.7 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ37359.1 - 0.0014 19.0 1.0 0.0014 19.0 1.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ37359.1 - 0.0041 17.0 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 KEZ37359.1 - 0.012 15.8 0.3 0.071 13.3 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KEZ37359.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Plasmodium_HRP PF05403.11 KEZ37359.1 - 0.02 14.7 13.6 0.029 14.2 13.6 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) SMC_N PF02463.19 KEZ37359.1 - 0.038 13.4 0.0 4.5 6.6 0.1 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ37359.1 - 0.088 13.1 0.4 0.29 11.4 0.4 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ37359.1 - 0.17 11.7 0.0 14 5.5 0.0 2.2 2 0 0 2 2 2 0 NTPase Alpha_GJ PF03229.13 KEZ37359.1 - 0.97 10.0 10.5 1.8 9.2 6.8 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Etmic-2 PF06670.11 KEZ37359.1 - 2.5 6.9 6.9 4.4 6.1 6.9 1.3 1 0 0 1 1 1 0 Microneme protein Etmic-2 BPD_transp_1 PF00528.22 KEZ37360.1 - 5.8e-26 91.4 13.0 7.9e-26 90.9 13.0 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component NMT1 PF09084.11 KEZ37361.1 - 4.7e-15 56.1 0.0 8.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KEZ37361.1 - 1.7e-12 47.4 0.1 2.8e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KEZ37361.1 - 2.8e-09 36.8 0.0 4.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 KEZ37361.1 - 6.5e-08 32.6 0.1 1.2e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 KEZ37361.1 - 0.016 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family YhfZ_C PF14503.6 KEZ37361.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain TauD PF02668.16 KEZ37362.1 - 2.9e-50 171.6 0.1 3.4e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1287 PF06940.11 KEZ37362.1 - 0.12 12.0 0.0 8.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) pPIWI_RE_Z PF18155.1 KEZ37362.1 - 0.15 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z ROK PF00480.20 KEZ37363.1 - 6e-26 91.6 0.0 7.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KEZ37363.1 - 1.7e-05 24.6 0.8 1.7e-05 24.6 0.8 3.0 4 0 0 4 4 4 1 MarR family HTH_IclR PF09339.10 KEZ37363.1 - 0.00071 19.3 4.0 0.0012 18.6 0.9 3.0 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KEZ37363.1 - 0.014 14.9 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DprA_WH PF17782.1 KEZ37363.1 - 0.016 15.3 0.6 0.094 12.8 0.1 2.6 2 0 0 2 2 2 0 DprA winged helix domain HTH_AsnC-type PF13404.6 KEZ37363.1 - 0.03 14.2 0.3 0.088 12.6 0.3 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR PF01047.22 KEZ37363.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family Peptidase_M48 PF01435.18 KEZ37364.1 - 7.5e-11 42.2 0.1 1.2e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KEZ37364.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 KEZ37364.1 - 0.0056 16.5 0.3 0.0083 16.0 0.3 1.2 1 0 0 1 1 1 1 SprT-like family Penicillinase_R PF03965.16 KEZ37365.1 - 7.7e-25 87.5 0.1 9.3e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 KEZ37365.1 - 5.9e-05 22.9 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 KEZ37365.1 - 0.0014 18.5 0.2 0.0031 17.4 0.1 1.6 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain MarR PF01047.22 KEZ37365.1 - 0.0021 17.9 0.1 0.0034 17.3 0.1 1.4 1 0 0 1 1 1 1 MarR family FUR PF01475.19 KEZ37365.1 - 0.004 17.3 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_27 PF13463.6 KEZ37365.1 - 0.0061 17.0 0.1 0.015 15.7 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 KEZ37365.1 - 0.011 15.7 1.9 0.039 13.8 1.9 2.0 1 1 0 1 1 1 0 MarR family Phycobilisome PF00502.19 KEZ37365.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Phycobilisome protein LexA_DNA_bind PF01726.16 KEZ37365.1 - 0.094 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 LexA DNA binding domain PadR PF03551.14 KEZ37365.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 KEZ37365.1 - 0.18 11.9 2.6 0.13 12.3 0.6 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Cyt_bd_oxida_I PF01654.17 KEZ37366.1 - 2.1e-122 408.8 11.0 2.4e-122 408.6 11.0 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cyt_bd_oxida_II PF02322.15 KEZ37367.1 - 6.5e-61 206.3 26.5 7.5e-61 206.1 26.5 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II B12D PF06522.11 KEZ37367.1 - 1.3 8.9 3.1 46 3.9 0.6 3.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CPBP PF02517.16 KEZ37368.1 - 1.6e-13 50.8 4.2 2.1e-12 47.2 2.6 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease YvrJ PF12841.7 KEZ37368.1 - 0.016 14.7 3.3 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 YvrJ protein family CHAD PF05235.14 KEZ37369.1 - 3.2e-48 164.7 15.6 6.1e-48 163.8 15.6 1.5 1 0 0 1 1 1 1 CHAD domain CYTH PF01928.21 KEZ37369.1 - 3.6e-13 49.8 0.0 7.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 CYTH domain ANTAR PF03861.14 KEZ37369.1 - 0.46 10.4 5.7 0.25 11.2 0.3 2.8 2 0 0 2 2 2 0 ANTAR domain CSD PF00313.22 KEZ37370.1 - 4.2e-31 106.6 1.4 4.5e-31 106.5 1.4 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KEZ37370.1 - 6.8e-05 22.5 1.1 0.00011 21.9 1.1 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 KEZ37370.1 - 0.00059 20.1 0.0 0.00065 20.0 0.0 1.1 1 0 0 1 1 1 1 S1 RNA binding domain Semialdhyde_dhC PF02774.18 KEZ37371.1 - 1.6e-43 148.9 0.0 2.1e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KEZ37371.1 - 2.3e-27 95.8 0.2 4.3e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KEZ37371.1 - 0.037 13.6 1.0 0.056 13.0 0.1 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain AA_kinase PF00696.28 KEZ37372.1 - 3e-56 190.7 2.8 4.1e-56 190.3 2.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KEZ37372.1 - 1.7e-17 62.9 2.1 2e-10 40.2 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KEZ37372.1 - 3.3e-15 55.6 0.4 5.2e-12 45.4 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.6 KEZ37372.1 - 0.00059 19.8 0.2 1.5 8.9 0.0 2.8 2 0 0 2 2 2 2 ACT domain TerD PF02342.18 KEZ37373.1 - 1.4e-72 243.1 0.0 1.5e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 TerD domain ADH_N PF08240.12 KEZ37374.1 - 1.2e-28 99.2 0.4 1.9e-28 98.5 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ37374.1 - 3.1e-09 36.9 0.4 1.2e-08 35.1 0.2 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ37374.1 - 0.00037 21.6 0.2 0.0019 19.3 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase zf-ANAPC11 PF12861.7 KEZ37374.1 - 0.055 13.5 0.8 0.76 9.9 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger YdjM PF04307.14 KEZ37375.1 - 5e-06 25.9 6.9 0.00021 20.6 0.1 2.7 1 1 1 2 2 2 2 LexA-binding, inner membrane-associated putative hydrolase DUF4235 PF14019.6 KEZ37375.1 - 0.59 10.3 6.0 4.5 7.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4235) Toprim_4 PF13662.6 KEZ37377.1 - 1.8e-24 86.0 0.0 4.6e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 Toprim domain RecR PF02132.15 KEZ37377.1 - 2.9e-16 58.7 2.7 5.6e-16 57.8 2.7 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 KEZ37377.1 - 4.6e-08 33.2 0.0 9.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HHH PF00633.23 KEZ37377.1 - 2.1e-06 27.3 0.1 7e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KEZ37377.1 - 0.00096 19.7 0.0 0.0033 18.0 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Toprim_2 PF13155.6 KEZ37377.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Toprim-like HHH_8 PF14716.6 KEZ37377.1 - 0.15 12.4 0.1 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_3 PF12836.7 KEZ37377.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif YbaB_DNA_bd PF02575.16 KEZ37378.1 - 3e-29 101.1 0.1 3.8e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF2710 PF10921.8 KEZ37378.1 - 0.032 14.6 0.1 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) DNA_pol3_delta2 PF13177.6 KEZ37379.1 - 7.7e-37 126.6 0.0 1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 KEZ37379.1 - 1.3e-12 47.9 0.4 2.3e-12 47.0 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA PF00004.29 KEZ37379.1 - 2.6e-09 37.6 0.0 7.5e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEZ37379.1 - 6.6e-05 22.7 0.0 0.00039 20.2 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ37379.1 - 0.00015 22.0 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ37379.1 - 0.00018 21.9 2.2 0.00064 20.1 0.1 2.7 2 2 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 KEZ37379.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KEZ37379.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KEZ37379.1 - 0.011 15.4 0.1 0.058 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KEZ37379.1 - 0.023 14.7 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KEZ37379.1 - 0.098 12.7 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KEZ37379.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Herpes_Helicase PF02689.14 KEZ37379.1 - 0.13 10.1 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF3106 PF11304.8 KEZ37385.1 - 0.054 14.0 1.3 0.095 13.2 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Glycos_transf_2 PF00535.26 KEZ37386.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37386.1 - 0.069 13.0 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ37386.1 - 0.096 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 TPR_12 PF13424.6 KEZ37387.1 - 1.7 9.0 16.8 1.5 9.2 2.4 3.4 3 1 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 KEZ37388.1 - 8.9e-28 96.0 2.6 2.5e-08 34.5 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat TIR_2 PF13676.6 KEZ37388.1 - 6.1e-22 78.5 0.1 9.6e-21 74.6 0.0 2.9 3 0 0 3 3 3 1 TIR domain ANAPC4_WD40 PF12894.7 KEZ37388.1 - 3.6e-10 40.0 0.0 0.00096 19.4 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KEZ37388.1 - 2.3e-08 34.6 2.5 2.3e-08 34.6 2.5 2.9 2 2 0 2 2 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 KEZ37388.1 - 6.3e-06 25.4 0.0 0.014 14.4 0.0 3.3 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ37388.1 - 0.0036 17.2 1.4 10 6.2 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 KEZ37388.1 - 0.014 15.3 0.9 5.6 6.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KEZ37388.1 - 0.021 14.7 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TIR PF01582.20 KEZ37388.1 - 0.042 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 TIR domain ATPase_2 PF01637.18 KEZ37388.1 - 0.12 12.2 0.1 0.5 10.2 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KEZ37388.1 - 0.2 12.0 2.4 0.23 11.7 0.2 2.3 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEZ37388.1 - 0.29 11.0 0.1 0.59 10.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Proteasome_A_N PF10584.9 KEZ37388.1 - 1.3 8.8 13.0 3.8 7.3 0.0 4.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF4326 PF14216.6 KEZ37389.1 - 1.7e-22 79.9 0.0 2.1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) Pyridoxal_deC PF00282.19 KEZ37390.1 - 3.5e-48 164.2 0.0 4.5e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KEZ37390.1 - 5.3e-06 25.9 0.0 7.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KEZ37390.1 - 0.00067 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KEZ37390.1 - 0.2 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II MafB19-deam PF14437.6 KEZ37391.1 - 7.7e-30 103.4 0.0 9.6e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KEZ37391.1 - 4.2e-25 87.6 0.0 5.6e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KEZ37391.1 - 1.6e-05 25.0 1.8 0.0012 18.9 0.5 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase DUF1727 PF08353.10 KEZ37393.1 - 1.5e-23 82.8 0.0 2.8e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1727) Mur_ligase_M PF08245.12 KEZ37393.1 - 1.8e-15 57.4 0.0 5.9e-15 55.8 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain GATase_3 PF07685.14 KEZ37394.1 - 8.1e-27 94.1 0.0 1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KEZ37394.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KEZ37394.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Esterase_phd PF10503.9 KEZ37395.1 - 2.3e-05 24.0 0.0 0.00038 20.0 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase NLPC_P60 PF00877.19 KEZ37396.1 - 2.9e-21 75.4 0.1 4.9e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 KEZ37396.1 - 0.041 13.6 0.1 1.1 8.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) CHAP PF05257.16 KEZ37396.1 - 0.059 14.0 0.0 0.17 12.5 0.0 1.8 1 1 0 1 1 1 0 CHAP domain DUF4686 PF15742.5 KEZ37397.1 - 0.002 17.3 1.2 0.0023 17.1 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Mce4_CUP1 PF11887.8 KEZ37397.1 - 0.021 14.3 0.6 0.025 14.1 0.6 1.0 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Virulence_fact PF13769.6 KEZ37397.1 - 0.3 11.3 3.8 1.2 9.4 3.7 1.9 1 1 1 2 2 2 0 Virulence factor ZapB PF06005.12 KEZ37397.1 - 0.33 11.4 5.6 0.34 11.4 0.7 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DNA_pol_A_exoN PF18305.1 KEZ37397.1 - 0.73 10.2 5.3 4 7.8 4.1 2.1 1 1 1 2 2 2 0 3' to 5' exonuclease C-terminal domain CorA PF01544.18 KEZ37398.1 - 4.7e-59 200.1 0.1 5.6e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0122 PF04297.14 KEZ37398.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like PhzC-PhzF PF02567.16 KEZ37399.1 - 9.1e-17 61.4 0.0 1.8e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Hemerythrin PF01814.23 KEZ37400.1 - 3.2e-14 53.7 1.0 3.2e-14 53.7 1.0 1.9 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain DUF2590 PF10761.9 KEZ37400.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) SpoIIE PF07228.12 KEZ37401.1 - 3e-33 115.4 0.0 5.4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 KEZ37401.1 - 1.8e-11 44.2 0.0 2.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain CHASE3 PF05227.13 KEZ37402.1 - 3.6e-29 101.4 0.5 3.6e-29 101.4 0.5 2.4 2 0 0 2 2 2 1 CHASE3 domain HATPase_c PF02518.26 KEZ37402.1 - 2.9e-19 69.6 0.0 5.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ37402.1 - 2.9e-13 49.6 0.0 1.1e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ37402.1 - 1.2e-07 32.0 0.9 3.4e-07 30.5 0.1 2.3 2 0 0 2 2 2 1 HAMP domain DUF4864 PF16156.5 KEZ37402.1 - 0.21 12.3 0.2 0.35 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) MDMPI_N PF11716.8 KEZ37403.1 - 5e-06 27.2 5.6 5e-06 27.2 5.6 2.9 1 1 2 3 3 3 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 KEZ37403.1 - 0.0069 17.2 6.9 0.0069 17.2 6.9 2.4 1 1 1 2 2 2 1 MDMPI C-terminal domain Glyco_hydro_26 PF02156.15 KEZ37404.1 - 3.4e-10 39.9 0.1 5.1e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Cellulase PF00150.18 KEZ37404.1 - 0.061 12.7 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) CD225 PF04505.12 KEZ37405.1 - 1.7e-23 82.5 3.0 2.3e-23 82.1 3.0 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ETRAMP PF09716.10 KEZ37405.1 - 0.00047 20.1 0.2 0.0007 19.6 0.2 1.1 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) SNARE PF05739.19 KEZ37405.1 - 0.0034 17.4 1.4 0.0063 16.5 1.4 1.4 1 0 0 1 1 1 1 SNARE domain STE3 PF02076.15 KEZ37405.1 - 0.027 13.7 0.1 0.033 13.4 0.1 1.0 1 0 0 1 1 1 0 Pheromone A receptor FtsX PF02687.21 KEZ37405.1 - 0.039 14.4 5.0 0.059 13.8 5.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF898 PF05987.13 KEZ37405.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4134 PF13572.6 KEZ37405.1 - 0.14 12.5 2.5 0.2 11.9 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) CD225 PF04505.12 KEZ37406.1 - 8.1e-14 51.5 0.5 1.3e-13 50.8 0.5 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DnaJ PF00226.31 KEZ37406.1 - 3.9e-10 39.7 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain rve_3 PF13683.6 KEZ37407.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Aminotran_1_2 PF00155.21 KEZ37408.1 - 1.4e-43 149.5 0.0 1.7e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ37408.1 - 1.7e-07 30.1 0.0 2.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ37408.1 - 9.7e-06 25.1 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KEZ37408.1 - 0.00039 19.5 0.0 0.00054 19.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V ApbA PF02558.16 KEZ37409.1 - 1.3e-33 115.8 0.0 1.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEZ37409.1 - 4.5e-20 72.1 0.0 6.5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 KEZ37409.1 - 0.00037 21.0 0.0 0.0015 19.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KEZ37409.1 - 0.017 15.0 0.4 0.066 13.1 0.4 2.0 1 1 0 1 1 1 0 Rossmann-like domain p450 PF00067.22 KEZ37410.1 - 3.3e-26 92.0 0.0 9e-18 64.3 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 ThiS PF02597.20 KEZ37410.1 - 4.3e-10 40.1 0.1 9.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 ThiS family PP2C_2 PF13672.6 KEZ37410.1 - 0.0032 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Prok-JAB PF14464.6 KEZ37411.1 - 0.00032 20.5 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PIN_3 PF13470.6 KEZ37413.1 - 5.6e-17 62.6 0.1 8.4e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 PIN domain PIN_2 PF10130.9 KEZ37413.1 - 0.00025 21.3 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 PIN domain PsiB PF06290.11 KEZ37413.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Plasmid SOS inhibition protein (PsiB) HTH_17 PF12728.7 KEZ37414.1 - 2.9e-11 43.4 0.2 4.9e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 KEZ37414.1 - 0.012 15.4 0.2 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_Crp_2 PF13545.6 KEZ37414.1 - 0.045 13.7 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RWP-RK PF02042.15 KEZ37414.1 - 0.053 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 RWP-RK domain HTH_29 PF13551.6 KEZ37414.1 - 0.11 12.6 1.3 0.33 11.0 0.1 2.5 2 1 1 3 3 3 0 Winged helix-turn helix ANT PF03374.14 KEZ37414.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain HTH_31 PF13560.6 KEZ37414.1 - 0.23 11.8 6.1 1.5 9.3 6.0 2.4 1 1 0 1 1 1 0 Helix-turn-helix domain DUF4037 PF13228.6 KEZ37415.1 - 5.2e-27 94.6 0.0 8.7e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) FR47 PF08445.10 KEZ37416.1 - 1.2e-08 34.8 0.0 4.3e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KEZ37416.1 - 8.8e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KEZ37416.1 - 0.00012 22.8 0.0 0.00021 22.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ37416.1 - 0.0047 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ37416.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ37416.1 - 0.12 12.5 0.1 1 9.5 0.1 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_33 PF13671.6 KEZ37417.1 - 1e-13 51.7 0.0 1.6e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ37417.1 - 1.2e-05 25.8 0.0 0.0001 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEZ37417.1 - 0.0086 15.4 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 KEZ37417.1 - 0.22 12.0 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase InPase PF18823.1 KEZ37418.1 - 0.0023 17.7 0.1 0.0025 17.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic Pyrophosphatase Pyrophosphatase PF00719.19 KEZ37418.1 - 0.014 15.2 0.2 0.021 14.6 0.2 1.4 1 1 0 1 1 1 0 Inorganic pyrophosphatase Aminotran_5 PF00266.19 KEZ37419.1 - 1.6e-15 57.0 0.0 2.2e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MazE_antitoxin PF04014.18 KEZ37420.1 - 1.8e-08 34.1 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PIN PF01850.21 KEZ37421.1 - 8.5e-16 58.6 0.1 9.4e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 PIN domain Dimerisation2 PF16864.5 KEZ37421.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Response_reg PF00072.24 KEZ37422.1 - 7.7e-11 42.2 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ37422.1 - 1.3e-08 34.3 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 KEZ37422.1 - 0.00031 20.4 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KEZ37422.1 - 0.0008 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 KEZ37422.1 - 0.0019 17.9 0.1 0.0046 16.6 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 KEZ37422.1 - 0.004 16.9 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KEZ37422.1 - 0.0046 17.0 0.6 0.019 15.1 0.0 2.4 3 1 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ37422.1 - 0.0047 16.4 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KEZ37422.1 - 0.0047 16.3 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KEZ37422.1 - 0.015 15.3 0.1 0.074 13.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix DUF134 PF02001.16 KEZ37422.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF134 PG_binding_4 PF12229.8 KEZ37422.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain HTH_10 PF04967.12 KEZ37422.1 - 0.14 12.0 0.0 0.68 9.8 0.0 2.2 3 0 0 3 3 3 0 HTH DNA binding domain RTC_insert PF05189.13 KEZ37422.1 - 0.16 12.5 0.2 0.48 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain PK PF00224.21 KEZ37426.1 - 3.6e-120 401.0 0.2 4.5e-120 400.7 0.2 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KEZ37426.1 - 8.4e-28 96.9 0.2 2.9e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KEZ37426.1 - 3.1e-06 26.5 6.1 0.0023 17.1 3.2 3.0 2 1 1 3 3 3 2 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KEZ37426.1 - 0.042 12.9 0.1 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain ABC_membrane PF00664.23 KEZ37428.1 - 1e-35 123.7 9.0 1.3e-35 123.4 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ37428.1 - 4.3e-32 111.5 0.0 6.6e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ37428.1 - 2.3e-05 24.0 0.0 0.00063 19.2 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KEZ37428.1 - 0.0079 16.5 0.1 0.031 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEZ37428.1 - 0.0096 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 KEZ37428.1 - 0.011 16.1 1.4 0.059 13.8 1.4 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KEZ37428.1 - 0.017 15.6 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEZ37428.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KEZ37428.1 - 0.027 14.2 0.3 0.061 13.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEZ37428.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ37428.1 - 0.041 14.0 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ37428.1 - 0.045 13.6 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 KEZ37428.1 - 0.045 14.0 1.9 0.3 11.3 0.1 2.9 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KEZ37428.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ37428.1 - 0.075 12.6 0.7 0.38 10.3 0.7 2.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ37428.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 KEZ37428.1 - 0.19 11.5 0.2 2.5 7.8 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KEZ37428.1 - 0.22 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ECH_1 PF00378.20 KEZ37429.1 - 6.6e-17 61.7 0.1 8.6e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ37429.1 - 2.5e-05 23.9 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Cation_efflux PF01545.21 KEZ37432.1 - 1.5e-36 126.1 3.7 1.8e-36 125.8 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEZ37432.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF3099 PF11298.8 KEZ37432.1 - 1.3 9.2 4.9 2.6 8.2 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) ABC_tran PF00005.27 KEZ37433.1 - 5.9e-47 159.6 0.3 1.5e-22 80.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KEZ37433.1 - 1.6e-20 74.1 9.3 7.3e-05 22.7 0.0 4.8 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KEZ37433.1 - 4.6e-11 42.6 6.1 8.7e-11 41.7 6.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ37433.1 - 1.2e-10 41.3 0.1 0.012 15.1 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KEZ37433.1 - 2.2e-08 34.7 0.4 0.015 15.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain Arf PF00025.21 KEZ37433.1 - 2.7e-06 27.0 0.0 0.0027 17.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_23 PF13476.6 KEZ37433.1 - 3.4e-06 27.7 0.2 0.24 11.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KEZ37433.1 - 4e-06 26.5 0.4 0.2 11.4 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEZ37433.1 - 1.1e-05 25.5 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 KEZ37433.1 - 1.2e-05 25.4 1.0 0.071 13.3 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KEZ37433.1 - 2.2e-05 24.7 3.9 0.18 11.9 0.1 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEZ37433.1 - 3.6e-05 23.7 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEZ37433.1 - 6.5e-05 23.4 8.8 0.014 15.8 0.2 2.8 3 0 0 3 3 2 2 AAA ATPase domain PduV-EutP PF10662.9 KEZ37433.1 - 7.1e-05 22.6 0.1 0.18 11.6 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KEZ37433.1 - 7.2e-05 23.1 3.5 0.16 12.2 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KEZ37433.1 - 7.7e-05 23.0 0.2 0.24 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KEZ37433.1 - 0.00017 21.5 0.8 0.8 9.6 0.1 2.7 3 0 0 3 3 2 2 NACHT domain AAA_13 PF13166.6 KEZ37433.1 - 0.00041 19.2 6.7 0.2 10.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain RuvB_N PF05496.12 KEZ37433.1 - 0.00056 19.7 0.1 0.34 10.7 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KEZ37433.1 - 0.00084 19.3 1.1 0.41 10.6 0.0 3.0 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KEZ37433.1 - 0.00096 18.8 0.4 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA PF00004.29 KEZ37433.1 - 0.0014 19.0 0.3 1.4 9.4 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 KEZ37433.1 - 0.0016 16.1 13.5 0.1 10.1 0.3 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) cobW PF02492.19 KEZ37433.1 - 0.0022 17.6 3.3 1 8.9 0.1 2.8 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KEZ37433.1 - 0.0038 16.8 0.2 3.8 7.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain Roc PF08477.13 KEZ37433.1 - 0.0048 17.1 0.2 4.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 KEZ37433.1 - 0.0053 16.6 0.1 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 KEZ37433.1 - 0.007 16.1 0.0 0.83 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KEZ37433.1 - 0.0083 15.9 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DLIC PF05783.11 KEZ37433.1 - 0.0084 15.0 0.1 0.089 11.6 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 KEZ37433.1 - 0.012 15.3 6.3 1.3 8.8 0.0 3.4 3 1 0 3 3 3 0 AAA domain DUF612 PF04747.12 KEZ37433.1 - 0.02 14.1 1.1 0.027 13.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Zeta_toxin PF06414.12 KEZ37433.1 - 0.021 14.1 0.1 2.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 KEZ37433.1 - 0.034 14.2 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEZ37433.1 - 0.057 12.6 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 KEZ37433.1 - 0.1 12.3 0.1 8.7 6.0 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 KEZ37433.1 - 0.12 12.5 1.2 7.4 6.6 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain dNK PF01712.19 KEZ37433.1 - 0.12 12.2 0.7 17 5.2 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 KEZ37433.1 - 0.24 11.3 0.0 23 4.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KEZ37433.1 - 0.25 11.7 0.1 12 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_27 PF13514.6 KEZ37433.1 - 0.27 10.8 6.1 3.8 7.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain DUF724 PF05266.14 KEZ37433.1 - 0.28 11.0 1.8 0.47 10.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_17 PF13207.6 KEZ37433.1 - 0.42 11.0 5.2 24 5.3 0.4 3.7 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 KEZ37433.1 - 4.5 6.2 10.8 0.81 8.6 0.1 3.5 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 KEZ37433.1 - 5.1 6.7 5.8 12 5.5 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase GDP_Man_Dehyd PF16363.5 KEZ37435.1 - 1e-76 258.5 0.0 1.2e-76 258.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ37435.1 - 6.8e-64 215.6 0.0 8e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ37435.1 - 2.1e-16 59.9 0.0 7.7e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEZ37435.1 - 9e-15 54.4 0.0 1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEZ37435.1 - 9.7e-14 51.1 0.0 1.2e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KEZ37435.1 - 3.4e-12 46.1 0.0 7.4e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KEZ37435.1 - 1.1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEZ37435.1 - 0.00098 18.6 0.1 0.008 15.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KEZ37435.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family FtsJ PF01728.19 KEZ37435.1 - 0.066 13.3 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glycos_transf_1 PF00534.20 KEZ37436.1 - 3.6e-33 114.5 0.0 6.1e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ37436.1 - 1.6e-30 106.3 1.3 2.8e-30 105.5 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ37436.1 - 2.1e-28 99.5 3.8 1.7e-27 96.5 2.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KEZ37436.1 - 2.5e-19 70.3 14.9 2.5e-19 70.3 14.9 2.6 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ37436.1 - 3.9e-13 49.6 0.0 9.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KEZ37436.1 - 2.5e-05 24.1 0.2 0.0057 16.4 0.1 2.2 2 0 0 2 2 2 2 Starch synthase catalytic domain NTP_transferase PF00483.23 KEZ37437.1 - 4.3e-63 213.2 0.0 5.6e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ37437.1 - 4.9e-07 30.2 0.1 7.6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KEZ37437.1 - 0.098 12.4 0.3 0.098 12.4 0.3 3.8 3 1 1 4 4 4 0 Bacterial transferase hexapeptide (six repeats) FeS_assembly_P PF01883.19 KEZ37438.1 - 5.2e-20 71.4 1.2 9.8e-20 70.5 1.2 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein NifU_N PF01592.16 KEZ37439.1 - 3.9e-31 107.8 0.0 6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Aminotran_5 PF00266.19 KEZ37440.1 - 3.4e-137 457.3 0.0 4.4e-137 457.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ37440.1 - 4.3e-05 23.0 0.0 0.00054 19.4 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEZ37440.1 - 0.0012 17.5 0.0 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEZ37440.1 - 0.023 13.9 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II ABC_tran PF00005.27 KEZ37441.1 - 1.8e-21 77.1 0.0 2.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ37441.1 - 2.8e-06 26.9 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ37441.1 - 0.00075 19.4 0.1 0.074 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ37441.1 - 0.00075 19.2 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KEZ37441.1 - 0.0015 17.3 0.0 0.15 10.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEZ37441.1 - 0.01 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 KEZ37441.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEZ37441.1 - 0.049 13.4 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ37441.1 - 0.054 14.0 0.0 0.083 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ37441.1 - 0.063 13.7 0.1 0.67 10.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KEZ37441.1 - 0.18 11.4 0.1 0.4 10.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain Rieske PF00355.26 KEZ37442.1 - 1.3e-18 66.7 0.0 1.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KEZ37442.1 - 7.9e-12 45.0 0.0 9.6e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0051 PF01458.17 KEZ37443.1 - 1.9e-71 240.2 0.0 2.3e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.17 KEZ37444.1 - 7.8e-73 244.8 0.2 9.9e-73 244.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) HTH_5 PF01022.20 KEZ37445.1 - 1.8e-08 34.1 0.0 3.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 KEZ37445.1 - 2.2e-08 34.0 1.1 5.4e-08 32.7 1.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 KEZ37445.1 - 6.1e-08 32.1 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KEZ37445.1 - 1.2e-06 28.5 0.3 3.7e-06 26.9 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ37445.1 - 3.3e-06 26.9 3.2 1e-05 25.3 0.8 2.7 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 KEZ37445.1 - 5.4e-05 23.0 0.0 8.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 KEZ37445.1 - 0.0001 22.3 0.1 0.00034 20.7 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 KEZ37445.1 - 0.00041 20.0 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR PF01047.22 KEZ37445.1 - 0.0005 20.0 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 KEZ37445.1 - 0.00052 19.8 2.3 0.0006 19.6 0.6 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 KEZ37445.1 - 0.0019 18.0 1.7 0.002 17.9 0.2 1.9 2 0 0 2 2 1 1 IclR helix-turn-helix domain TrmB PF01978.19 KEZ37445.1 - 0.0028 17.5 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 KEZ37445.1 - 0.0037 17.0 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 LexA DNA binding domain RP-C PF03428.13 KEZ37445.1 - 0.0061 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain AbiEi_4 PF13338.6 KEZ37445.1 - 0.0082 16.3 0.2 0.02 15.0 0.2 1.7 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin PadR PF03551.14 KEZ37445.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_23 PF13384.6 KEZ37445.1 - 0.017 14.9 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain FeoC PF09012.10 KEZ37445.1 - 0.027 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator KfrA_N PF11740.8 KEZ37445.1 - 0.03 15.0 1.2 1.7 9.4 0.1 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HTH_27 PF13463.6 KEZ37445.1 - 0.033 14.7 0.1 0.07 13.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_34 PF13601.6 KEZ37445.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Dimerisation2 PF16864.5 KEZ37445.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain HTH_Crp_2 PF13545.6 KEZ37445.1 - 0.074 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_9 PF08221.11 KEZ37445.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KEZ37445.1 - 0.077 12.4 0.1 0.36 10.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 KEZ37445.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain FGGY_N PF00370.21 KEZ37447.1 - 1.2e-66 224.7 0.0 1.7e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KEZ37447.1 - 1.3e-53 181.6 0.5 5.1e-53 179.8 0.9 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KEZ37447.1 - 0.018 14.5 0.1 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family HTH_31 PF13560.6 KEZ37448.1 - 5.1e-10 39.6 7.4 5.1e-10 39.6 7.4 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ37448.1 - 7.7e-09 35.5 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ37448.1 - 7.2e-07 29.1 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ37448.1 - 0.01 15.7 1.2 0.023 14.6 1.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 KEZ37449.1 - 1.7e-23 83.6 0.0 2.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ37449.1 - 5.4e-11 42.8 0.0 3.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ37449.1 - 8.7e-05 22.1 0.0 0.092 12.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain KdpD PF02702.17 KEZ37449.1 - 0.0018 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_30 PF13604.6 KEZ37449.1 - 0.0019 17.9 0.5 0.0062 16.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KEZ37449.1 - 0.0058 16.4 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KEZ37449.1 - 0.015 15.5 0.1 0.27 11.5 0.1 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KEZ37449.1 - 0.022 15.3 0.2 0.031 14.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEZ37449.1 - 0.053 13.2 0.5 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ37449.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain LPD18 PF18832.1 KEZ37449.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 SRP54 PF00448.22 KEZ37449.1 - 0.17 11.5 0.3 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KEZ37449.1 - 0.47 10.0 3.1 3 7.4 3.1 2.2 1 1 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KEZ37450.1 - 1.7e-21 76.6 5.4 2.4e-21 76.1 5.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ37450.1 - 3.8e-17 62.4 1.5 3.8e-17 62.4 1.5 1.2 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEZ37450.1 - 1.3e-08 34.5 14.9 1.3e-08 34.5 14.9 1.7 1 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KEZ37450.1 - 0.0005 20.1 2.6 0.00083 19.4 2.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein COX15-CtaA PF02628.15 KEZ37451.1 - 7.9e-25 87.6 33.9 3.3e-14 52.7 25.0 3.0 1 1 1 2 2 2 2 Cytochrome oxidase assembly protein FMN_red PF03358.15 KEZ37452.1 - 2.1e-22 79.6 0.0 2.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEZ37452.1 - 0.0095 15.7 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.16 KEZ37453.1 - 0.0083 15.1 3.5 0.013 14.4 3.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KEZ37453.1 - 0.5 10.1 4.2 0.29 10.9 0.4 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like UbiA PF01040.18 KEZ37455.1 - 1.2e-66 224.6 24.9 1.7e-66 224.1 24.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TAL_FSA PF00923.19 KEZ37456.1 - 6.3e-83 278.4 0.0 7.1e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase G6PD_C PF02781.16 KEZ37457.1 - 3.8e-112 374.2 0.0 4.5e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KEZ37457.1 - 5e-58 196.6 0.0 6.7e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain OpcA_G6PD_assem PF10128.9 KEZ37458.1 - 1.1e-76 257.7 2.0 1.4e-76 257.4 2.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit Glucosamine_iso PF01182.20 KEZ37459.1 - 1.9e-69 234.0 0.0 2.2e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SHOCT PF09851.9 KEZ37460.1 - 7.8e-09 35.0 0.7 1.1e-08 34.5 0.7 1.2 1 0 0 1 1 1 1 Short C-terminal domain PLDc_N PF13396.6 KEZ37460.1 - 3.3e-08 33.3 10.6 3.3e-08 33.3 10.6 2.2 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF2207 PF09972.9 KEZ37460.1 - 0.06 12.1 0.5 0.063 12.0 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OSTbeta PF15048.6 KEZ37460.1 - 0.068 13.3 2.3 0.081 13.1 0.0 1.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Phage_holin_3_6 PF07332.11 KEZ37460.1 - 0.1 12.7 5.3 0.15 12.1 5.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4834 PF16118.5 KEZ37460.1 - 0.27 12.2 0.9 0.7 10.9 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Tad PF13400.6 KEZ37460.1 - 3.1 8.2 5.3 5.6 7.4 0.2 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Pkinase PF00069.25 KEZ37461.1 - 3.9e-37 128.0 0.0 5.5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ37461.1 - 6.1e-20 71.6 0.0 8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ37461.1 - 6.3e-05 23.0 4.8 0.00048 20.1 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ37461.1 - 0.00056 18.8 0.0 0.00096 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEZ37461.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KEZ37461.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3742 PF12553.8 KEZ37461.1 - 0.52 10.4 2.6 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) RbpA PF13397.6 KEZ37462.1 - 2.1e-41 140.7 0.1 2.4e-41 140.6 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase-binding protein Rubredoxin PF00301.20 KEZ37462.1 - 0.002 18.1 0.4 0.0034 17.4 0.4 1.4 1 0 0 1 1 1 1 Rubredoxin SBP_bac_5 PF00496.22 KEZ37463.1 - 6.4e-31 107.7 0.0 9.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle LPAM_1 PF08139.12 KEZ37463.1 - 5 7.8 4.7 14 6.4 4.7 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SecG PF03840.14 KEZ37464.1 - 1.2e-17 63.7 9.1 1.4e-17 63.6 9.1 1.0 1 0 0 1 1 1 1 Preprotein translocase SecG subunit TIM PF00121.18 KEZ37465.1 - 5.6e-84 281.3 0.0 6.3e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PGK PF00162.19 KEZ37466.1 - 2.4e-138 461.2 0.0 2.7e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Gp_dh_C PF02800.20 KEZ37467.1 - 5.2e-65 217.9 0.1 7.3e-65 217.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KEZ37467.1 - 6.4e-35 119.5 0.2 2.4e-34 117.7 0.1 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KEZ37467.1 - 0.0098 16.5 0.1 0.038 14.7 0.1 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Mannitol_dh PF01232.23 KEZ37467.1 - 0.044 13.9 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Semialdhyde_dhC PF02774.18 KEZ37467.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain WhiA_N PF10298.9 KEZ37468.1 - 6.1e-26 90.3 0.0 1.4e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 WhiA N-terminal LAGLIDADG-like domain LAGLIDADG_WhiA PF14527.6 KEZ37468.1 - 9.2e-24 83.3 0.0 1.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 WhiA LAGLIDADG-like domain HTH_WhiA PF02650.14 KEZ37468.1 - 1.7e-11 44.3 0.0 2.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 WhiA C-terminal HTH domain DUF2065 PF09838.9 KEZ37468.1 - 0.78 9.8 3.5 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) UPF0052 PF01933.18 KEZ37469.1 - 4.5e-68 229.6 0.0 5.5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ATP_bind_2 PF03668.15 KEZ37470.1 - 1.5e-105 352.5 0.0 1.7e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 KEZ37470.1 - 0.0083 16.7 0.1 1.3 9.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 KEZ37470.1 - 0.1 12.8 0.1 0.8 9.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain UvrC_HhH_N PF08459.11 KEZ37471.1 - 1.5e-49 167.8 0.0 3.3e-49 166.7 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal UVR PF02151.19 KEZ37471.1 - 5.5e-11 41.8 6.2 1.1e-10 40.9 5.0 2.2 2 0 0 2 2 2 1 UvrB/uvrC motif HHH_5 PF14520.6 KEZ37471.1 - 7.7e-10 39.2 1.7 8.8e-10 39.1 0.3 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain GIY-YIG PF01541.24 KEZ37471.1 - 1.9e-09 37.6 0.0 4.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH_2 PF12826.7 KEZ37471.1 - 1.3e-08 34.8 0.0 5e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KEZ37471.1 - 7.2e-05 22.5 0.2 0.00045 19.9 0.2 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 KEZ37471.1 - 0.0015 18.7 0.3 0.025 14.9 0.2 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KEZ37471.1 - 0.043 14.4 0.2 20 5.8 0.1 3.1 2 1 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DUF99 PF01949.16 KEZ37471.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 CorA PF01544.18 KEZ37471.1 - 0.22 10.8 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SsgA PF04686.12 KEZ37472.1 - 1.3e-22 79.7 0.1 1.7e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA UvrA_inter PF17760.1 KEZ37473.1 - 8e-40 135.3 0.0 1.8e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 KEZ37473.1 - 2.7e-38 130.7 0.0 5.9e-35 120.0 0.0 3.4 3 0 0 3 3 3 1 UvrA DNA-binding domain ABC_tran PF00005.27 KEZ37473.1 - 9.2e-18 65.1 0.0 3e-10 40.7 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_16 PF13191.6 KEZ37473.1 - 1.6e-09 38.4 2.0 0.003 17.9 0.1 3.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 KEZ37473.1 - 8e-09 35.1 0.1 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ37473.1 - 4.6e-07 30.5 0.0 0.014 15.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KEZ37473.1 - 1.2e-06 28.6 0.2 0.0065 16.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ37473.1 - 3.4e-06 26.7 0.0 2.9 7.3 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEZ37473.1 - 1.4e-05 25.0 0.1 0.051 13.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KEZ37473.1 - 1.5e-05 24.7 0.0 0.076 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KEZ37473.1 - 0.00029 21.0 0.0 1.3 9.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain APS_kinase PF01583.20 KEZ37473.1 - 0.00034 20.5 0.1 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_18 PF13238.6 KEZ37473.1 - 0.00056 20.5 0.0 0.66 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ37473.1 - 0.00096 19.4 0.0 0.8 10.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KEZ37473.1 - 0.0013 18.6 0.1 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 KEZ37473.1 - 0.0065 16.5 0.6 0.41 10.7 0.1 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KEZ37473.1 - 0.0088 15.2 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 KEZ37473.1 - 0.012 15.9 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 KEZ37473.1 - 0.013 14.6 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KEZ37473.1 - 0.016 14.8 0.3 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 KEZ37473.1 - 0.028 14.1 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.18 KEZ37473.1 - 0.031 14.0 0.1 0.43 10.3 0.0 2.4 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KEZ37473.1 - 0.034 14.1 0.1 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 KEZ37473.1 - 0.043 14.1 0.0 6.8 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.10 KEZ37473.1 - 0.055 13.6 6.8 19 5.4 0.0 4.4 4 0 0 4 4 4 0 Zinc ribbon domain CLU PF13236.6 KEZ37473.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Clustered mitochondria FANCL_C PF11793.8 KEZ37473.1 - 0.084 13.1 0.9 1.2 9.4 0.0 2.8 3 0 0 3 3 2 0 FANCL C-terminal domain AAA_15 PF13175.6 KEZ37473.1 - 0.1 12.2 0.0 22 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain DUF2075 PF09848.9 KEZ37473.1 - 0.11 11.7 0.2 2.1 7.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KEZ37473.1 - 0.15 12.1 0.0 6.7 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ37473.1 - 0.17 11.6 0.1 2.7 7.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF2083 PF09856.9 KEZ37473.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) DnaJ_CXXCXGXG PF00684.19 KEZ37473.1 - 0.26 11.7 9.9 0.22 11.9 0.2 3.8 5 0 0 5 5 3 0 DnaJ central domain DUF87 PF01935.17 KEZ37473.1 - 1.2 9.2 4.2 0.66 10.0 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Anti-TRAP PF15777.5 KEZ37473.1 - 6.7 6.8 10.0 23 5.0 0.0 4.3 4 1 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lactamase_B PF00753.27 KEZ37474.1 - 2e-10 41.0 7.5 3.1e-10 40.4 7.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 KEZ37474.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glycos_transf_2 PF00535.26 KEZ37475.1 - 2.6e-07 30.6 0.0 3.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37475.1 - 3.6e-07 30.3 0.1 5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 KEZ37475.1 - 0.00037 20.9 0.8 0.00037 20.9 0.8 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Glyco_trans_2_3 PF13632.6 KEZ37475.1 - 0.00049 20.1 1.6 0.0016 18.4 1.6 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 KEZ37475.1 - 0.00062 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KEZ37475.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 TerC PF03741.16 KEZ37476.1 - 5.2e-55 185.9 10.5 5.2e-55 185.9 10.5 1.6 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF475 PF04332.15 KEZ37476.1 - 2.3 7.9 14.9 0.056 13.2 7.4 2.1 2 1 0 3 3 3 0 Protein of unknown function (DUF475) CBS PF00571.28 KEZ37477.1 - 0.0023 18.4 3.1 0.68 10.4 0.0 3.5 4 0 0 4 4 4 2 CBS domain UvrB_inter PF17757.1 KEZ37478.1 - 7e-33 112.7 0.1 4.3e-32 110.1 0.1 2.2 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 KEZ37478.1 - 2.5e-20 72.0 0.7 6.4e-20 70.7 0.7 1.8 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 KEZ37478.1 - 8e-17 61.6 0.1 1.7e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UVR PF02151.19 KEZ37478.1 - 2.7e-10 39.7 7.6 9e-10 38.0 7.6 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.15 KEZ37478.1 - 3.1e-09 37.1 0.0 1.1e-07 32.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEZ37478.1 - 1.3e-05 25.0 0.3 0.048 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 KEZ37478.1 - 4.2e-05 23.4 0.0 0.00065 19.5 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KEZ37478.1 - 0.00044 20.6 0.1 0.23 11.8 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KEZ37478.1 - 0.0036 17.3 0.0 0.013 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ37478.1 - 0.007 16.8 0.2 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ37478.1 - 0.0096 16.2 0.8 0.088 13.1 0.0 2.9 4 0 0 4 4 4 1 AAA domain Helicase_RecD PF05127.14 KEZ37478.1 - 0.01 15.7 0.0 0.031 14.1 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF87 PF01935.17 KEZ37478.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain FEZ PF07763.13 KEZ37478.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 FEZ-like protein CoaE PF01121.20 KEZ37479.1 - 1.9e-51 174.3 0.0 2.5e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KEZ37479.1 - 0.0003 21.0 0.3 0.0053 16.9 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ37479.1 - 0.0033 18.0 0.8 0.87 10.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEZ37479.1 - 0.1 12.9 2.4 0.2 11.9 0.1 2.3 2 2 0 2 2 2 0 AAA domain GYD PF08734.11 KEZ37479.1 - 0.18 11.8 3.0 5.1 7.1 0.0 2.5 2 1 0 2 2 2 0 GYD domain DUF2630 PF10944.8 KEZ37479.1 - 1.9 9.0 4.6 1.4 9.4 2.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2630) SNARE_assoc PF09335.11 KEZ37480.1 - 0.024 15.1 4.7 0.056 13.9 4.7 1.7 1 0 0 1 1 1 0 SNARE associated Golgi protein Peptidase_M4_C PF02868.15 KEZ37481.1 - 3.1e-53 180.1 0.0 4.4e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KEZ37481.1 - 2.7e-30 105.8 0.0 4.1e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 KEZ37481.1 - 2.4e-07 30.4 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Protealysin propeptide EAL PF00563.20 KEZ37482.1 - 3.6e-67 226.4 0.0 4.8e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KEZ37482.1 - 8.1e-27 93.9 0.0 7.9e-18 64.7 0.0 2.2 2 0 0 2 2 2 2 Diguanylate cyclase, GGDEF domain DNA_pol_A PF00476.20 KEZ37483.1 - 1.2e-137 459.0 0.0 1.5e-137 458.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 KEZ37483.1 - 3.1e-51 173.4 0.0 5e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KEZ37483.1 - 7.2e-23 81.0 0.0 1.6e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold WYL PF13280.6 KEZ37483.1 - 0.03 14.4 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 WYL domain HHH_5 PF14520.6 KEZ37483.1 - 0.16 12.6 0.0 0.57 10.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peripla_BP_6 PF13458.6 KEZ37484.1 - 1.9e-48 165.9 5.8 2.5e-48 165.5 5.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KEZ37484.1 - 2.6e-16 59.7 0.0 3.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KEZ37485.1 - 5.4e-41 141.4 13.3 1.2e-38 133.7 8.2 2.1 2 0 0 2 2 2 2 Periplasmic binding protein ANF_receptor PF01094.28 KEZ37485.1 - 3.6e-19 69.1 0.0 6.3e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KEZ37485.1 - 7.9e-07 28.4 0.0 1.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein domain GARS_N PF02844.15 KEZ37485.1 - 0.037 14.8 0.1 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Response_reg PF00072.24 KEZ37486.1 - 1.4e-29 102.5 0.1 2.2e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain ANTAR PF03861.14 KEZ37486.1 - 8.6e-22 76.7 1.0 8.6e-22 76.7 1.0 2.2 2 0 0 2 2 2 1 ANTAR domain RE_XamI PF09572.10 KEZ37486.1 - 0.066 12.9 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 XamI restriction endonuclease DUF899 PF05988.12 KEZ37488.1 - 4.8e-61 206.0 0.0 6.9e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Flavodoxin_5 PF12724.7 KEZ37490.1 - 4e-05 23.9 0.0 6.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KEZ37490.1 - 8.9e-05 22.7 0.0 0.0002 21.6 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 KEZ37490.1 - 0.0013 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Methyltransf_19 PF04672.12 KEZ37491.1 - 1.1e-115 385.7 0.4 1.4e-115 385.5 0.4 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase NAD_kinase PF01513.21 KEZ37491.1 - 0.17 11.0 0.0 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 ATP-NAD kinase FAM72 PF14976.6 KEZ37492.1 - 0.068 13.3 0.1 0.068 13.3 0.1 1.0 1 0 0 1 1 1 0 FAM72 protein GGDEF PF00990.21 KEZ37493.1 - 1.5e-34 119.1 0.0 2.7e-34 118.3 0.0 1.4 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HMG-CoA_red PF00368.18 KEZ37493.1 - 0.079 11.9 0.2 0.17 10.9 0.1 1.5 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A reductase NLPC_P60 PF00877.19 KEZ37494.1 - 9.1e-09 35.3 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family DUF305 PF03713.13 KEZ37496.1 - 1.2e-55 187.9 5.1 1.5e-55 187.5 5.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 KEZ37496.1 - 3.3e-13 50.1 0.6 5.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4142) LPAM_1 PF08139.12 KEZ37496.1 - 3.6 8.3 6.7 17 6.1 6.7 2.1 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Chromate_transp PF02417.15 KEZ37497.1 - 2.6e-65 219.4 32.1 7e-33 114.0 15.6 2.1 2 0 0 2 2 2 2 Chromate transporter p450 PF00067.22 KEZ37498.1 - 2.8e-27 95.6 0.0 5.1e-24 84.9 0.0 2.9 1 1 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.24 KEZ37499.1 - 1.1e-24 87.6 22.8 1.1e-24 87.6 22.8 1.5 1 1 1 2 2 2 1 Fatty acid desaturase PP-binding PF00550.25 KEZ37500.1 - 7.3e-19 67.9 0.0 8.8e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site CMAS PF02353.20 KEZ37501.1 - 2e-65 220.8 0.0 2.3e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KEZ37501.1 - 2.9e-08 34.3 0.0 6.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ37501.1 - 3.5e-07 30.8 0.0 7.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37501.1 - 0.00016 22.4 0.0 0.00027 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ37501.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ37501.1 - 0.00017 21.4 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KEZ37501.1 - 0.0011 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KEZ37501.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 KEZ37502.1 - 2.1e-32 112.5 0.0 2.3e-27 95.9 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 Thioesterase PF00975.20 KEZ37503.1 - 1.5e-37 129.9 0.1 1.7e-37 129.7 0.1 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KEZ37503.1 - 1e-07 32.8 16.2 1.3e-07 32.5 16.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ37503.1 - 2.3e-06 27.1 0.0 0.0046 16.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ37503.1 - 1.9e-05 24.5 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KEZ37503.1 - 2.2e-05 24.2 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KEZ37503.1 - 0.00085 18.9 0.0 0.012 15.2 0.1 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KEZ37503.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase AMP-binding PF00501.28 KEZ37504.1 - 5.9e-90 301.9 0.0 7.1e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme fn3 PF00041.21 KEZ37505.1 - 1.1e-10 41.7 0.1 2.9e-09 37.1 0.0 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Glyco_hydro_18 PF00704.28 KEZ37505.1 - 0.00045 20.0 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Fer4_19 PF06902.11 KEZ37506.1 - 2e-11 43.8 0.0 2.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_15 PF13459.6 KEZ37506.1 - 1.6e-10 41.6 1.1 1.8e-10 41.4 1.1 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KEZ37506.1 - 2.5e-08 34.3 0.0 2.8e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I p450 PF00067.22 KEZ37507.1 - 5.6e-30 104.5 0.0 9.6e-24 83.9 0.3 3.2 2 1 0 2 2 2 2 Cytochrome P450 ABC_tran PF00005.27 KEZ37511.1 - 1.8e-29 103.0 0.0 3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEZ37511.1 - 3e-26 92.7 5.9 3.8e-26 92.4 5.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KEZ37511.1 - 8.9e-05 22.0 0.2 0.0071 15.8 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ37511.1 - 0.027 14.2 0.4 0.074 12.8 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KEZ37511.1 - 0.097 12.9 0.2 1.1 9.5 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KEZ37511.1 - 0.16 12.2 1.3 12 6.2 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KEZ37511.1 - 0.24 11.2 0.0 0.77 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KEZ37511.1 - 0.36 10.4 8.8 0.32 10.5 2.8 3.5 3 1 0 3 3 3 0 AAA domain DUF308 PF03729.13 KEZ37512.1 - 4.2e-14 52.6 24.8 1.6e-08 34.7 0.6 4.0 1 1 3 4 4 4 3 Short repeat of unknown function (DUF308) TraQ PF09679.10 KEZ37512.1 - 0.084 12.8 6.1 5.5 7.0 0.1 3.2 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) Intg_mem_TP0381 PF09529.10 KEZ37512.1 - 0.11 12.0 5.4 1.2 8.5 5.4 2.4 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) YrhK PF14145.6 KEZ37512.1 - 0.43 10.5 5.6 0.32 10.9 1.6 2.6 2 1 0 2 2 2 0 YrhK-like protein ThrE PF06738.12 KEZ37512.1 - 0.94 8.8 8.1 0.27 10.6 3.4 2.0 2 0 0 2 2 2 0 Putative threonine/serine exporter CDP-OH_P_transf PF01066.21 KEZ37512.1 - 2.5 8.9 8.8 0.68 10.8 4.1 2.4 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase AMP-binding PF00501.28 KEZ37513.1 - 5.9e-49 166.8 2.0 1.3e-46 159.1 2.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KEZ37513.1 - 3.2e-08 33.8 0.5 1.1e-07 32.1 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Acyl_transf_3 PF01757.22 KEZ37513.1 - 3.9e-05 22.9 15.8 9.4e-05 21.6 15.8 1.6 1 1 0 1 1 1 1 Acyltransferase family CcmF_C PF16327.5 KEZ37513.1 - 3.3 6.9 8.9 1.3 8.2 4.5 2.2 1 1 1 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal SBP_bac_6 PF13343.6 KEZ37514.1 - 2e-24 86.3 0.2 2.8e-24 85.9 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KEZ37514.1 - 1.8e-22 80.5 1.1 2.3e-22 80.1 1.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KEZ37514.1 - 2e-22 80.1 5.3 2.8e-22 79.6 5.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KEZ37514.1 - 4.6e-19 69.5 5.4 1.5e-18 67.8 5.4 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Arteri_nucleo PF01481.16 KEZ37514.1 - 0.0048 17.2 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 Arterivirus nucleocapsid protein DUF2059 PF09832.9 KEZ37514.1 - 0.015 15.4 0.3 0.042 13.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) BPD_transp_1 PF00528.22 KEZ37515.1 - 2.8e-26 92.4 32.3 2.2e-15 56.9 13.3 2.9 2 2 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KEZ37516.1 - 3.3e-31 108.6 0.0 8.2e-31 107.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KEZ37516.1 - 3.3e-08 33.7 0.6 0.0027 17.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 KEZ37516.1 - 5.4e-08 32.9 5.1 3.3e-07 30.4 2.7 2.8 2 1 0 2 2 1 1 TOBE domain TOBE PF03459.17 KEZ37516.1 - 3.8e-06 27.1 1.0 8.6e-06 26.0 0.3 2.0 2 0 0 2 2 1 1 TOBE domain SMC_N PF02463.19 KEZ37516.1 - 0.0009 18.7 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ37516.1 - 0.0058 17.0 1.1 0.0058 17.0 1.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 KEZ37516.1 - 0.012 15.1 0.5 0.043 13.4 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ37516.1 - 0.016 15.5 0.8 0.045 14.0 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ37516.1 - 0.019 14.7 0.9 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KEZ37516.1 - 0.023 14.9 0.1 0.2 11.9 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KEZ37516.1 - 0.028 14.9 0.4 0.19 12.2 0.5 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEZ37516.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ37516.1 - 0.072 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ37516.1 - 0.073 13.6 6.7 0.091 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEZ37516.1 - 0.075 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KEZ37516.1 - 0.19 11.0 0.2 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 KaiC Presenilin PF01080.17 KEZ37516.1 - 0.25 10.1 0.1 0.32 9.7 0.1 1.2 1 0 0 1 1 1 0 Presenilin Orf78 PF06024.12 KEZ37516.1 - 0.51 10.7 3.9 0.88 9.9 3.9 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4834 PF16118.5 KEZ37516.1 - 2.1 9.4 5.1 3.8 8.5 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_28 PF13521.6 KEZ37516.1 - 2.6 8.3 5.2 0.81 9.9 0.2 2.4 3 0 0 3 3 3 0 AAA domain RNase_II_C_S1 PF18614.1 KEZ37516.1 - 3.9 7.5 9.4 0.32 11.0 1.3 3.4 4 1 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain S4 PF01479.25 KEZ37517.1 - 8.1e-14 51.1 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.6 KEZ37517.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin Multi_ubiq PF14452.6 KEZ37517.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Multiubiquitin Polysacc_deac_1 PF01522.21 KEZ37519.1 - 3.5e-27 94.8 0.0 7.2e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glycos_transf_2 PF00535.26 KEZ37519.1 - 9.2e-20 71.1 0.0 1.7e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37519.1 - 1e-10 41.9 3.0 2.1e-10 40.9 0.2 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEZ37519.1 - 2.9e-07 30.3 0.0 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ37519.1 - 1.6e-06 28.2 0.1 2.4e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 KEZ37519.1 - 4.9e-06 26.1 0.0 9.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 KEZ37520.1 - 2.5e-25 89.3 0.1 3.7e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37520.1 - 7.3e-19 68.6 0.1 1.3e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEZ37520.1 - 3e-10 40.0 0.0 5.6e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ37520.1 - 4.3e-05 23.5 0.1 6.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KEZ37520.1 - 0.00071 19.1 0.3 0.0038 16.7 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7C PF02709.14 KEZ37520.1 - 0.037 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Methyltransf_11 PF08241.12 KEZ37521.1 - 9.4e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ37521.1 - 0.00092 19.0 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37521.1 - 0.0022 18.7 0.0 0.0033 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ37521.1 - 0.0046 16.8 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37521.1 - 0.059 14.1 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KEZ37521.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CrgA PF06781.12 KEZ37523.1 - 0.1 12.6 0.2 9.2 6.4 0.0 3.3 3 0 0 3 3 3 0 Cell division protein CrgA DUF1616 PF07760.11 KEZ37524.1 - 0.0002 20.8 5.7 0.00025 20.5 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) Sm_multidrug_ex PF06695.11 KEZ37524.1 - 0.037 14.7 2.6 0.037 14.7 2.6 1.5 1 1 0 1 1 1 0 Putative small multi-drug export protein LHC PF00556.20 KEZ37524.1 - 0.35 11.1 0.5 0.35 11.1 0.5 3.1 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit Glycos_transf_2 PF00535.26 KEZ37525.1 - 1.8e-20 73.4 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37525.1 - 2.2e-17 63.7 0.0 3.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ37525.1 - 1.4e-06 27.9 0.0 6.1e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KEZ37525.1 - 9.5e-05 22.4 0.1 0.00018 21.5 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 KEZ37525.1 - 0.00089 18.8 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ37526.1 - 4.5e-24 85.2 0.0 8.7e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Polysacc_deac_1 PF01522.21 KEZ37526.1 - 3.8e-23 81.7 0.0 8.2e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_tranf_2_3 PF13641.6 KEZ37526.1 - 1.8e-14 54.2 0.2 4.3e-14 53.0 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ37526.1 - 8.8e-07 28.6 0.1 3.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KEZ37526.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 KEZ37526.1 - 0.00079 19.0 0.0 0.0065 16.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ37527.1 - 2.5e-23 82.7 0.0 3.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37527.1 - 6.2e-10 39.3 0.2 1e-09 38.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ37527.1 - 0.0065 16.0 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KEZ37527.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Bac_transf PF02397.16 KEZ37528.1 - 2.2e-67 226.2 0.0 3.5e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 KEZ37528.1 - 6.8e-13 49.0 3.2 9.5e-13 48.5 0.7 2.0 2 0 0 2 2 2 1 CoA-binding domain DUF3054 PF11255.8 KEZ37528.1 - 1.3 9.6 8.4 0.2 12.2 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Glycos_transf_2 PF00535.26 KEZ37529.1 - 2.9e-22 79.3 0.0 4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37529.1 - 4.8e-17 62.6 0.0 1.2e-16 61.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ37529.1 - 7.8e-08 32.5 0.7 4.4e-07 30.0 0.7 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 KEZ37529.1 - 4.4e-06 26.4 0.0 0.0054 16.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KEZ37529.1 - 0.00059 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 KEZ37529.1 - 0.0031 17.0 0.0 0.012 15.0 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KEZ37529.1 - 0.053 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.6 KEZ37529.1 - 0.19 11.4 0.0 1.1 8.9 0.0 2.1 2 1 0 2 2 2 0 Glycosyltransferase like family Glyco_trans_1_4 PF13692.6 KEZ37531.1 - 4.3e-17 62.8 0.0 7.4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ37531.1 - 1.8e-15 56.9 0.0 3.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ37531.1 - 1.1e-12 48.1 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 KEZ37532.1 - 1.6e-14 54.1 0.0 2.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37532.1 - 9.9e-08 32.1 0.1 1.6e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Beta_helix PF13229.6 KEZ37533.1 - 7.6e-10 38.9 6.1 5.1e-09 36.2 5.7 2.0 1 1 1 2 2 2 2 Right handed beta helix region CPT_N PF16484.5 KEZ37533.1 - 0.18 11.8 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Glyco_trans_1_4 PF13692.6 KEZ37534.1 - 6.5e-09 36.3 0.0 3.8e-08 33.8 0.0 2.1 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ37534.1 - 0.005 16.4 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Polysacc_synt_3 PF13440.6 KEZ37535.1 - 2.8e-79 266.4 11.1 4.8e-79 265.6 11.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 KEZ37535.1 - 4.4e-32 111.6 18.1 4.4e-32 111.6 18.1 2.5 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 KEZ37535.1 - 0.0005 20.2 12.0 0.0005 20.2 12.0 3.9 2 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF4175 PF13779.6 KEZ37535.1 - 0.16 9.8 4.0 0.34 8.8 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Wzy_C PF04932.15 KEZ37536.1 - 2.4e-07 30.5 2.0 2.4e-07 30.5 2.0 4.1 3 2 0 3 3 3 1 O-Antigen ligase Wzz PF02706.15 KEZ37537.1 - 1.8e-07 31.4 2.0 2.1e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 Chain length determinant protein Glycos_transf_2 PF00535.26 KEZ37538.1 - 6.4e-24 84.7 0.0 8.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37538.1 - 3.5e-08 33.6 0.0 5.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KEZ37538.1 - 0.0025 18.3 0.0 0.0047 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_1 PF00232.18 KEZ37538.1 - 0.017 13.5 0.0 0.024 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Methyltransf_23 PF13489.6 KEZ37539.1 - 9e-14 51.6 0.0 2.4e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_14 PF08484.11 KEZ37539.1 - 8.3e-08 32.2 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_11 PF08241.12 KEZ37539.1 - 0.00083 20.0 0.0 0.0021 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37539.1 - 0.0026 18.5 0.2 0.014 16.2 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37539.1 - 0.074 13.8 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TF_Zn_Ribbon PF08271.12 KEZ37539.1 - 0.15 11.6 1.9 13 5.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Methyltransf_13 PF08421.11 KEZ37539.1 - 0.19 12.0 0.7 0.75 10.1 0.2 2.1 2 0 0 2 2 2 0 Putative zinc binding domain DUF35_N PF12172.8 KEZ37539.1 - 0.26 11.2 4.8 10 6.1 0.4 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Methyltransf_23 PF13489.6 KEZ37540.1 - 5.6e-18 65.3 0.0 9.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_14 PF08484.11 KEZ37540.1 - 2.2e-15 56.8 0.0 4.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_9 PF08003.11 KEZ37540.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 KEZ37540.1 - 0.00028 21.5 0.0 0.0017 19.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37540.1 - 0.00029 21.5 0.1 0.0025 18.5 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37540.1 - 0.001 19.7 0.4 0.0093 16.7 0.4 2.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ37540.1 - 0.013 14.8 0.4 0.092 12.0 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_13 PF08421.11 KEZ37540.1 - 0.017 15.4 0.4 0.035 14.4 0.4 1.6 1 0 0 1 1 1 0 Putative zinc binding domain Methyltransf_31 PF13847.6 KEZ37540.1 - 0.027 14.3 0.3 0.17 11.7 0.3 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ37540.1 - 0.11 11.9 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Putative methyltransferase zinc_ribbon_2 PF13240.6 KEZ37540.1 - 2.3 8.0 4.0 27 4.7 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Epimerase PF01370.21 KEZ37541.1 - 6.8e-40 137.0 0.0 8.3e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ37541.1 - 5.7e-21 75.3 0.0 1.5e-20 73.9 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEZ37541.1 - 4.6e-13 48.9 0.0 5.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEZ37541.1 - 1.6e-09 37.2 0.0 3.5e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEZ37541.1 - 9.3e-05 22.1 0.2 0.18 11.4 0.0 3.0 3 0 0 3 3 3 2 NmrA-like family Polysacc_synt_2 PF02719.15 KEZ37541.1 - 0.00013 21.2 0.0 0.019 14.1 0.0 3.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEZ37541.1 - 0.00032 20.6 0.0 0.0013 18.7 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NTP_transferase PF00483.23 KEZ37542.1 - 6.5e-13 48.8 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ37542.1 - 7.2e-06 26.4 0.0 1.3e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Glyco_trans_1_4 PF13692.6 KEZ37543.1 - 4e-17 62.9 0.0 6.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ37543.1 - 2.7e-15 56.8 0.6 5e-15 55.9 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KEZ37543.1 - 4.9e-15 56.3 3.0 4.9e-15 56.3 3.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KEZ37543.1 - 3.7e-10 39.6 0.0 6.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ37543.1 - 8e-10 38.9 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KEZ37543.1 - 5.7e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 AcetylCoA_hyd_C PF13336.6 KEZ37544.1 - 3.8e-43 147.1 0.0 5.8e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KEZ37544.1 - 0.054 11.8 0.4 0.33 9.2 0.1 2.2 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter GAF_2 PF13185.6 KEZ37545.1 - 5.4e-28 98.0 13.9 9.5e-19 68.1 0.5 3.2 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KEZ37545.1 - 5.9e-22 78.4 2.0 2.7e-10 40.7 0.6 3.2 3 0 0 3 3 3 2 GAF domain GAF PF01590.26 KEZ37545.1 - 7.2e-20 72.0 6.6 3.3e-12 47.2 0.0 2.6 3 0 0 3 3 3 2 GAF domain HisKA_3 PF07730.13 KEZ37545.1 - 9.6e-11 42.1 3.3 9.6e-11 42.1 3.3 3.0 4 0 0 4 4 4 1 Histidine kinase HATPase_c PF02518.26 KEZ37545.1 - 2.9e-06 27.8 0.0 2e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KEZ37545.1 - 5.1e-06 26.5 0.1 1.3e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KEZ37545.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1876 PF08962.11 KEZ37547.1 - 1.7e-29 101.6 3.1 1.8e-29 101.5 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1876) LytR_cpsA_psr PF03816.14 KEZ37548.1 - 1.8e-40 138.6 0.0 2.7e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 KEZ37548.1 - 2e-14 54.3 1.9 2e-14 54.3 1.9 2.1 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator adh_short PF00106.25 KEZ37549.1 - 3.5e-42 144.1 0.1 4.1e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ37549.1 - 3.4e-33 115.2 0.0 4.2e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ37549.1 - 9.8e-10 38.6 0.5 1.9e-09 37.7 0.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ37549.1 - 0.027 14.0 0.0 0.039 13.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ37549.1 - 0.045 12.7 0.0 0.075 12.0 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SpoIIE PF07228.12 KEZ37551.1 - 6.3e-35 120.8 0.9 9e-35 120.3 0.9 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) FUSC_2 PF13515.6 KEZ37551.1 - 0.33 11.1 4.7 0.53 10.4 4.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like MerR_1 PF13411.6 KEZ37552.1 - 2.9e-17 62.5 0.1 4.9e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ37552.1 - 1.2e-12 47.4 0.3 1.2e-12 47.4 0.3 2.1 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KEZ37552.1 - 2.8e-05 24.5 8.6 0.0002 21.8 5.4 2.9 2 1 0 2 2 2 1 MerR, DNA binding MerR_2 PF13591.6 KEZ37552.1 - 0.0078 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein Mago-bind PF09282.10 KEZ37552.1 - 0.01 15.7 0.2 2.7 7.9 0.0 2.9 1 1 1 2 2 2 0 Mago binding HTH_30 PF13556.6 KEZ37552.1 - 0.063 13.1 0.6 11 5.9 0.3 2.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Hemerythrin PF01814.23 KEZ37552.1 - 0.24 12.0 4.0 0.47 11.1 2.7 2.1 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain MFS_1 PF07690.16 KEZ37553.1 - 3.2e-38 131.6 66.0 4.9e-37 127.7 60.4 3.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ37553.1 - 2.3e-06 26.8 26.8 1.3e-05 24.2 8.8 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KEZ37553.1 - 0.0046 15.4 7.2 0.0046 15.4 7.2 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector CLN3 PF02487.17 KEZ37553.1 - 0.026 13.6 1.7 0.045 12.8 1.7 1.3 1 0 0 1 1 1 0 CLN3 protein OATP PF03137.20 KEZ37553.1 - 5.9 5.0 9.4 0.18 10.1 1.1 2.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GPP34 PF05719.11 KEZ37554.1 - 0.011 15.8 0.9 0.014 15.4 0.9 1.1 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) AAA_30 PF13604.6 KEZ37555.1 - 9.1e-44 149.5 0.8 1.8e-43 148.5 0.1 1.9 2 0 0 2 2 1 1 AAA domain HHH_4 PF14490.6 KEZ37555.1 - 1.2e-37 127.7 0.0 5.9e-31 106.3 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix containing domain AAA_19 PF13245.6 KEZ37555.1 - 1.4e-32 113.0 0.1 4e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KEZ37555.1 - 2.8e-20 71.9 0.8 7.9e-20 70.4 0.8 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 KEZ37555.1 - 5.9e-18 64.5 0.0 1.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 KEZ37555.1 - 1.9e-10 40.9 0.2 7.8e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase HHH_5 PF14520.6 KEZ37555.1 - 5.2e-10 39.8 0.9 5.2e-07 30.2 0.1 4.2 4 1 0 4 4 4 1 Helix-hairpin-helix domain AAA_11 PF13086.6 KEZ37555.1 - 3.7e-06 26.9 0.8 0.014 15.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 KEZ37555.1 - 4.2e-05 23.5 3.4 0.0012 18.7 3.4 2.5 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 KEZ37555.1 - 0.00065 19.0 0.0 0.0023 17.2 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase UvrD_C PF13361.6 KEZ37555.1 - 0.0029 17.1 0.0 0.023 14.1 0.1 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain HHH_2 PF12826.7 KEZ37555.1 - 0.0045 17.1 0.1 0.025 14.7 0.0 2.3 3 0 0 3 3 2 1 Helix-hairpin-helix motif AAA_22 PF13401.6 KEZ37555.1 - 0.0047 17.2 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KEZ37555.1 - 0.022 14.2 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 KEZ37555.1 - 0.035 14.5 1.6 0.093 13.1 0.7 2.2 1 1 1 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KEZ37555.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain HHH_3 PF12836.7 KEZ37555.1 - 0.07 13.4 0.0 1.4 9.3 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 KEZ37555.1 - 0.084 13.2 0.1 27 5.3 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif AAA_10 PF12846.7 KEZ37555.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.12 KEZ37555.1 - 0.12 12.3 0.0 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain DAP3 PF10236.9 KEZ37555.1 - 0.25 10.5 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TetR_N PF00440.23 KEZ37556.1 - 6e-15 54.8 0.2 1.4e-14 53.6 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 KEZ37556.1 - 1.2e-09 38.0 4.5 2.5e-09 37.1 4.5 1.4 1 0 0 1 1 1 1 MftR C-terminal domain HTH_7 PF02796.15 KEZ37556.1 - 0.0042 17.1 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 KEZ37556.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 KEZ37556.1 - 0.04 13.7 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain TetR_C_16 PF17920.1 KEZ37556.1 - 0.092 13.0 11.2 3.1 8.1 0.8 3.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 KEZ37556.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family CENP-B_N PF04218.13 KEZ37556.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain 3HCDH_N PF02737.18 KEZ37557.1 - 7.6e-54 182.3 0.5 1.1e-53 181.8 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ37557.1 - 1.4e-30 105.8 0.0 3.4e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEZ37557.1 - 4.6e-05 23.6 1.4 0.00012 22.3 1.4 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ37557.1 - 0.0007 20.1 0.7 0.0017 18.9 0.7 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 KEZ37557.1 - 0.0086 15.3 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ37557.1 - 0.0098 15.5 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ37557.1 - 0.014 15.6 0.3 0.045 14.0 0.4 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ37557.1 - 0.038 13.2 1.8 0.33 10.1 1.8 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KEZ37557.1 - 0.039 13.9 0.1 0.058 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 KEZ37557.1 - 0.041 14.2 3.6 0.5 10.6 3.1 2.5 1 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KEZ37557.1 - 0.054 12.9 0.2 0.1 11.9 0.2 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 KEZ37557.1 - 0.065 13.1 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pyr_redox PF00070.27 KEZ37557.1 - 0.066 13.8 1.9 0.14 12.7 0.5 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KEZ37557.1 - 0.068 12.7 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KEZ37557.1 - 0.13 12.5 2.2 0.39 11.0 0.4 2.3 1 1 1 2 2 2 0 TrkA-N domain Rossmann-like PF10727.9 KEZ37557.1 - 0.21 11.4 2.6 0.43 10.5 2.2 1.8 1 1 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.20 KEZ37557.1 - 0.44 10.6 2.8 7.1 6.7 0.7 2.2 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Acyl-CoA_dh_1 PF00441.24 KEZ37558.1 - 2.7e-48 164.0 6.4 4.1e-48 163.4 6.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ37558.1 - 7.6e-28 97.4 0.0 1.4e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ37558.1 - 1.4e-26 92.5 0.0 2.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ37558.1 - 3.8e-26 92.0 3.4 3.8e-26 92.0 3.4 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB PF03241.13 KEZ37558.1 - 0.025 13.7 0.2 0.045 12.8 0.2 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Snf7 PF03357.21 KEZ37558.1 - 0.2 11.2 0.3 0.34 10.5 0.3 1.3 1 0 0 1 1 1 0 Snf7 ADH_zinc_N_2 PF13602.6 KEZ37559.1 - 1.3e-15 58.6 3.7 2.2e-15 57.9 1.5 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ37559.1 - 1.8e-11 44.1 3.6 3.1e-11 43.4 3.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ37559.1 - 1.4e-08 34.6 0.0 7.1e-08 32.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KEZ37559.1 - 0.3 11.3 2.0 0.38 10.9 1.1 1.7 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FR47 PF08445.10 KEZ37560.1 - 8.4e-27 93.0 0.0 1.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KEZ37560.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ37560.1 - 6.4e-10 39.3 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ37560.1 - 7.8e-09 35.6 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ37560.1 - 5.3e-06 26.5 0.0 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KEZ37560.1 - 8.1e-06 25.6 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 KEZ37560.1 - 0.00044 20.9 0.0 0.00059 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEZ37560.1 - 0.00069 19.3 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEZ37560.1 - 0.0042 17.2 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Pyridox_ox_2 PF12900.7 KEZ37561.1 - 3.3e-26 92.0 0.0 4.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ADH_N PF08240.12 KEZ37562.1 - 2e-12 46.9 0.2 2.8e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KEZ37562.1 - 0.0063 16.4 1.3 0.013 15.4 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated OxoDH_E1alpha_N PF12573.8 KEZ37562.1 - 0.25 11.1 6.7 0.32 10.8 2.1 2.5 2 1 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal GerE PF00196.19 KEZ37563.1 - 3.6e-16 58.4 1.7 6.4e-16 57.6 1.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family FCD PF07729.12 KEZ37565.1 - 3.4e-10 40.4 2.4 7e-10 39.4 2.4 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KEZ37565.1 - 2.1e-08 33.7 1.7 4.4e-08 32.7 1.7 1.5 1 1 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 KEZ37565.1 - 0.00013 22.3 0.1 0.00024 21.4 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 KEZ37565.1 - 0.00015 21.5 2.0 0.0012 18.7 0.3 2.9 2 1 0 2 2 2 1 MarR family HTH_29 PF13551.6 KEZ37565.1 - 0.022 14.8 0.7 0.054 13.5 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix PaaX PF07848.12 KEZ37565.1 - 0.028 14.6 0.1 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_Crp_2 PF13545.6 KEZ37565.1 - 0.039 13.9 0.2 0.09 12.8 0.2 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KEZ37565.1 - 0.083 13.0 0.6 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 KEZ37565.1 - 0.11 12.5 2.2 0.12 12.5 0.5 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KEZ37565.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_25 PF13649.6 KEZ37566.1 - 5.5e-16 59.0 0.0 1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37566.1 - 2.2e-12 47.6 0.0 3.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ37566.1 - 1.5e-11 44.8 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ37566.1 - 7.9e-09 35.5 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ37566.1 - 8.4e-09 35.2 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ37566.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KEZ37566.1 - 5.4e-06 26.3 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ37566.1 - 0.00026 20.4 0.0 0.00032 20.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMD PF02627.20 KEZ37566.1 - 0.032 14.3 0.3 0.094 12.8 0.3 1.8 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Methyltransf_PK PF05891.12 KEZ37566.1 - 0.051 13.1 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 KEZ37566.1 - 0.06 12.6 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KEZ37566.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Amidase_2 PF01510.25 KEZ37567.1 - 5.4e-14 52.7 0.3 8.6e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase ChaB PF06150.12 KEZ37568.1 - 1.6e-14 54.2 0.5 2.7e-14 53.5 0.5 1.4 1 0 0 1 1 1 1 ChaB Rho_N PF07498.12 KEZ37568.1 - 7e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Lsr2 PF11774.8 KEZ37568.1 - 0.33 11.1 4.2 0.13 12.4 1.1 1.9 1 1 2 3 3 3 0 Lsr2 MMPL PF03176.15 KEZ37569.1 - 3.3e-68 230.1 19.9 5.4e-40 137.3 3.0 2.3 2 0 0 2 2 2 2 MMPL family DUF1435 PF07256.12 KEZ37569.1 - 1.6 8.9 6.7 0.24 11.5 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) GerE PF00196.19 KEZ37570.1 - 9.3e-18 63.5 0.2 1.5e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family GAF_2 PF13185.6 KEZ37570.1 - 1.8e-08 34.8 0.2 3.7e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KEZ37570.1 - 0.00024 21.8 0.1 0.0004 21.0 0.1 1.4 1 0 0 1 1 1 1 GAF domain Bactofilin PF04519.13 KEZ37570.1 - 0.00093 19.4 0.0 0.0075 16.5 0.1 2.2 2 0 0 2 2 2 1 Polymer-forming cytoskeletal Sigma70_r4 PF04545.16 KEZ37570.1 - 0.0021 17.6 0.2 0.0083 15.6 0.2 2.1 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KEZ37570.1 - 0.0029 17.2 0.1 0.0067 16.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_30 PF13556.6 KEZ37570.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Chorion_1 PF01723.16 KEZ37570.1 - 0.5 10.3 8.6 0.89 9.5 2.8 3.1 1 1 1 2 2 2 0 Chorion protein RNase_H_2 PF13482.6 KEZ37571.1 - 3.1e-18 66.3 0.0 4.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNase_H superfamily AAA_12 PF13087.6 KEZ37571.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ37571.1 - 7.2e-13 48.9 0.2 2.7e-07 30.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ37571.1 - 1.5e-11 44.4 0.6 1.5e-11 44.4 0.6 2.7 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KEZ37571.1 - 3.6e-07 30.2 0.1 0.0025 17.6 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KEZ37571.1 - 8e-06 26.3 0.0 3.3e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ37571.1 - 2.4e-05 24.8 0.0 0.00013 22.5 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KEZ37571.1 - 0.00016 21.4 0.1 0.00051 19.8 0.1 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KEZ37571.1 - 0.011 15.5 0.1 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KEZ37571.1 - 0.012 15.9 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KEZ37571.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.14 KEZ37571.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 KEZ37571.1 - 0.073 13.0 0.0 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 KEZ37571.1 - 0.082 11.9 0.1 0.18 10.7 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KEZ37571.1 - 0.082 12.1 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KEZ37571.1 - 0.087 12.7 0.3 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 Helicase NACHT PF05729.12 KEZ37571.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KEZ37571.1 - 0.096 12.8 0.1 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEZ37571.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KEZ37571.1 - 0.27 11.0 0.0 0.41 10.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PEP_mutase PF13714.6 KEZ37572.1 - 4e-21 75.6 0.1 4.3e-21 75.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pantoate_transf PF02548.15 KEZ37572.1 - 2.4e-05 23.9 0.0 2.8e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase DDE_Tnp_IS66_C PF13817.6 KEZ37573.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 IS66 C-terminal element Cep57_CLD_2 PF14197.6 KEZ37575.1 - 0.00033 20.7 0.8 0.00045 20.2 0.8 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 CCDC-167 PF15188.6 KEZ37575.1 - 0.066 13.6 0.1 0.079 13.3 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Chibby PF14645.6 KEZ37575.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Chibby family IstB_IS21 PF01695.17 KEZ37576.1 - 3.4e-46 157.2 0.0 5e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 KEZ37576.1 - 2.7e-05 24.1 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein AFG1_ATPase PF03969.16 KEZ37576.1 - 0.00011 21.3 0.1 0.00031 19.8 0.0 1.6 1 1 1 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.6 KEZ37576.1 - 0.00034 21.0 5.4 0.0071 16.8 0.1 2.8 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ37576.1 - 0.00054 20.2 0.2 0.0046 17.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ37576.1 - 0.00054 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KEZ37576.1 - 0.0059 16.1 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 KEZ37576.1 - 0.0064 16.1 1.5 0.013 15.1 1.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEZ37576.1 - 0.015 14.8 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KEZ37576.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 KEZ37576.1 - 0.021 14.8 0.0 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KEZ37576.1 - 0.022 14.5 0.4 0.022 14.5 0.4 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEZ37576.1 - 0.024 15.2 0.0 0.054 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ37576.1 - 0.031 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RAMA PF18755.1 KEZ37576.1 - 0.075 13.4 0.2 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated RNA_helicase PF00910.22 KEZ37576.1 - 0.089 13.2 0.0 0.41 11.1 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 KEZ37576.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KEZ37576.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation rve PF00665.26 KEZ37577.1 - 4.8e-16 59.0 0.0 9.4e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_11 PF08279.12 KEZ37577.1 - 0.0019 18.1 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_28 PF13518.6 KEZ37577.1 - 0.0021 18.1 1.3 0.018 15.2 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 KEZ37577.1 - 0.0067 16.4 0.1 0.046 13.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KEZ37577.1 - 0.0082 15.9 1.0 0.036 13.9 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KEZ37577.1 - 0.027 14.2 0.1 0.063 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.19 KEZ37577.1 - 0.054 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family rve_3 PF13683.6 KEZ37577.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_36 PF13730.6 KEZ37577.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 KEZ37577.1 - 0.12 12.0 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 KEZ37577.1 - 0.16 11.5 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 KEZ37577.1 - 0.46 10.9 4.2 7.8 6.9 0.1 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_Tnp_1 PF01609.21 KEZ37579.1 - 3.2e-09 36.8 0.1 4e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain ABC_tran PF00005.27 KEZ37580.1 - 1.6e-15 57.8 0.0 1.1e-06 29.2 0.0 4.2 3 1 0 3 3 3 2 ABC transporter UvrA_DNA-bind PF17755.1 KEZ37580.1 - 3.5e-13 49.9 0.0 5.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 UvrA DNA-binding domain AAA_21 PF13304.6 KEZ37580.1 - 7.6e-12 45.6 0.8 0.0052 16.6 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KEZ37580.1 - 1.7e-05 24.5 0.5 0.083 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEZ37580.1 - 1.7e-05 25.2 1.6 0.68 10.3 0.1 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KEZ37580.1 - 2.8e-05 23.8 0.1 0.093 12.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ37580.1 - 0.00043 20.2 0.3 0.88 9.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KEZ37580.1 - 0.00088 19.4 0.2 0.36 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KEZ37580.1 - 0.0013 18.5 0.0 1.5 8.4 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.6 KEZ37580.1 - 0.0053 17.0 0.1 0.096 12.9 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KEZ37580.1 - 0.0058 16.9 0.5 13 6.1 0.3 3.8 3 1 1 4 4 4 0 AAA domain NACHT PF05729.12 KEZ37580.1 - 0.0074 16.2 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain DnaJ_CXXCXGXG PF00684.19 KEZ37580.1 - 0.0082 16.5 2.5 0.96 9.9 0.2 3.4 3 0 0 3 3 3 1 DnaJ central domain cobW PF02492.19 KEZ37580.1 - 0.016 14.8 0.7 4.2 6.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KEZ37580.1 - 0.057 12.8 0.0 46 3.3 0.0 3.6 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ37580.1 - 0.095 13.2 0.1 4.3 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KEZ37580.1 - 0.15 12.0 0.2 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 KEZ37580.1 - 0.2 12.2 0.8 15 6.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain Shal-type PF11601.8 KEZ37580.1 - 0.76 9.4 2.9 49 3.6 0.1 3.6 3 0 0 3 3 3 0 Shal-type voltage-gated potassium channels, N-terminal Putative_PNPOx PF01243.20 KEZ37581.1 - 0.0073 16.5 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AMP-binding PF00501.28 KEZ37582.1 - 2.6e-94 316.2 0.0 3.2e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KEZ37582.1 - 4.8e-29 102.1 0.0 1.2e-28 100.8 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KEZ37582.1 - 5.5e-14 52.3 0.1 2.2e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ37582.1 - 5.4e-09 36.9 0.1 1.4e-08 35.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_1 PF00561.20 KEZ37582.1 - 0.00057 19.6 0.2 0.00096 18.9 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Trp_halogenase PF04820.14 KEZ37583.1 - 1.7e-84 284.3 0.0 3.6e-61 207.4 0.0 2.0 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KEZ37583.1 - 1.2e-17 64.2 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ37583.1 - 1.7e-13 50.8 0.1 3.7e-13 49.6 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KEZ37583.1 - 4.6e-11 42.9 0.7 6.3e-05 22.7 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ37583.1 - 2.9e-10 39.8 0.6 0.00023 20.4 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 KEZ37583.1 - 2.9e-09 36.6 0.3 4.4e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ37583.1 - 3e-06 26.2 0.0 0.0018 17.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KEZ37583.1 - 3.8e-06 27.4 0.1 0.15 12.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ37583.1 - 6.1e-06 25.5 0.1 0.031 13.3 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ37583.1 - 0.0001 22.5 0.0 0.00044 20.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ37583.1 - 0.0003 20.0 0.0 0.0023 17.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KEZ37583.1 - 0.015 14.6 0.1 0.054 12.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 KEZ37583.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 KEZ37584.1 - 2.3e-31 108.4 2.8 4.1e-31 107.6 2.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ37584.1 - 1e-16 60.8 0.3 1.6e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M28 PF04389.17 KEZ37585.1 - 2.6e-36 125.2 0.0 3.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEZ37585.1 - 0.0026 17.5 0.0 0.0085 15.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KEZ37585.1 - 0.044 12.8 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase adh_short PF00106.25 KEZ37586.1 - 6.3e-22 78.0 0.0 1.5e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ37586.1 - 1.5e-20 73.8 0.0 3e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ37586.1 - 0.0037 17.2 0.3 0.0065 16.4 0.3 1.4 1 0 0 1 1 1 1 KR domain HTH_Tnp_1 PF01527.20 KEZ37587.1 - 4.2e-18 65.4 1.2 5.7e-18 65.0 1.2 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KEZ37587.1 - 4.2e-07 29.6 0.0 7.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KEZ37587.1 - 9.2e-07 28.2 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KEZ37587.1 - 7.5e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 KEZ37587.1 - 0.0014 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.6 KEZ37587.1 - 0.0024 17.6 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain Terminase_5 PF06056.12 KEZ37587.1 - 0.0027 17.6 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.13 KEZ37587.1 - 0.0028 17.2 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF1804 PF08822.11 KEZ37587.1 - 0.0074 16.3 0.4 0.018 15.1 0.3 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1804) Sigma70_r4_2 PF08281.12 KEZ37587.1 - 0.0084 15.8 0.1 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 KEZ37587.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Phage_terminase PF10668.9 KEZ37587.1 - 0.019 15.0 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 Phage terminase small subunit LZ_Tnp_IS481 PF13011.6 KEZ37587.1 - 0.026 15.1 0.0 0.033 14.7 0.0 1.3 1 1 0 1 1 1 0 leucine-zipper of insertion element IS481 Aldo_ket_red PF00248.21 KEZ37587.1 - 0.033 13.4 0.0 0.039 13.1 0.0 1.2 1 1 0 1 1 1 0 Aldo/keto reductase family DUF1079 PF06435.11 KEZ37587.1 - 0.064 13.5 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) HTH_18 PF12833.7 KEZ37587.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain KORA PF16509.5 KEZ37587.1 - 0.083 13.2 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor DUF746 PF05344.11 KEZ37587.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) rve PF00665.26 KEZ37588.1 - 3.8e-31 107.8 0.1 6.1e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 KEZ37588.1 - 7.8e-18 64.4 0.9 1.6e-17 63.3 0.9 1.4 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 KEZ37588.1 - 2.7e-14 53.1 0.3 4.9e-14 52.2 0.3 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KEZ37588.1 - 1.3e-13 50.5 0.0 2.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KEZ37588.1 - 1e-08 35.5 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 DDE domain DUF4043 PF13252.6 KEZ37588.1 - 0.044 12.9 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) HTH_Tnp_1 PF01527.20 KEZ37588.1 - 0.048 14.0 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF4761 PF15958.5 KEZ37588.1 - 0.06 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) DNase-RNase PF02577.14 KEZ37589.1 - 2.8e-44 149.9 0.0 3.3e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Bifunctional nuclease DUF4730 PF15873.5 KEZ37589.1 - 0.16 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4730) MerR_1 PF13411.6 KEZ37590.1 - 3e-13 49.6 0.0 4.3e-10 39.5 0.1 2.2 2 0 0 2 2 2 2 MerR HTH family regulatory protein MerR PF00376.23 KEZ37590.1 - 5.7e-11 42.0 0.9 1.5e-10 40.7 0.1 2.2 3 0 0 3 3 3 1 MerR family regulatory protein MerR_2 PF13591.6 KEZ37590.1 - 0.11 12.4 0.0 9.9 6.1 0.0 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein FHA PF00498.26 KEZ37591.1 - 5e-20 71.6 0.1 6.9e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEZ37591.1 - 1.8e-17 63.4 0.0 2.8e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zinc_ribbon_2 PF13240.6 KEZ37591.1 - 3.4e-07 29.8 1.9 6.1e-07 29.0 1.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KEZ37591.1 - 3.2e-05 23.9 1.1 5.3e-05 23.2 1.1 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.18 KEZ37591.1 - 0.00045 19.5 1.5 0.00076 18.7 1.5 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 KEZ37591.1 - 0.0015 17.9 1.3 0.0027 17.0 1.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-NADH-PPase PF09297.11 KEZ37591.1 - 0.002 17.7 1.6 0.17 11.6 0.1 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 KEZ37591.1 - 0.055 14.2 0.5 0.082 13.7 0.5 1.2 1 0 0 1 1 1 0 zinc-ribbon family Zn_ribbon_recom PF13408.6 KEZ37591.1 - 0.066 13.7 0.3 0.78 10.3 0.0 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HypA PF01155.19 KEZ37591.1 - 0.078 13.0 0.9 0.15 12.1 0.6 1.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FHA_2 PF17913.1 KEZ37591.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 FHA domain Nudix_N_2 PF14803.6 KEZ37591.1 - 0.13 12.2 2.6 4.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal zf_UBZ PF18439.1 KEZ37591.1 - 0.2 11.3 2.5 1.6 8.4 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger GCV_H PF01597.19 KEZ37592.1 - 2.8e-44 149.9 0.1 3e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KEZ37592.1 - 0.0073 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF881 PF05949.12 KEZ37593.1 - 3e-33 114.8 0.2 4.7e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) DUF1290 PF06947.12 KEZ37594.1 - 6e-27 93.6 3.2 8.8e-27 93.0 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) DUF881 PF05949.12 KEZ37595.1 - 6.1e-35 120.2 0.0 1.1e-34 119.4 0.0 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF881) NTP_transferase PF00483.23 KEZ37596.1 - 2e-52 178.3 0.0 2.8e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase PGM_PMM_II PF02879.16 KEZ37596.1 - 3.9e-17 62.8 0.0 1e-16 61.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 KEZ37596.1 - 4.1e-16 58.9 0.0 8.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I NTP_transf_3 PF12804.7 KEZ37596.1 - 6.9e-13 49.3 0.4 2.5e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep PF00132.24 KEZ37596.1 - 5.9e-11 41.6 1.1 0.0017 18.0 0.0 4.5 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) PGM_PMM_III PF02880.16 KEZ37596.1 - 1.2e-05 25.5 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Hexapep_2 PF14602.6 KEZ37596.1 - 0.026 14.3 0.8 11 5.8 0.0 4.0 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 KEZ37596.1 - 0.028 14.2 0.0 0.08 12.7 0.0 1.9 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4350 PF14258.6 KEZ37596.1 - 0.17 12.3 2.8 3.5 8.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) CDP-OH_P_transf PF01066.21 KEZ37597.1 - 7.3e-12 45.9 0.5 7.3e-12 45.9 0.5 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NLPC_P60 PF00877.19 KEZ37598.1 - 7.2e-25 87.0 0.0 1.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Big_3_5 PF16640.5 KEZ37598.1 - 0.00059 20.0 5.4 0.00059 20.0 5.4 2.3 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) CHAP PF05257.16 KEZ37598.1 - 0.0047 17.5 0.1 0.013 16.1 0.1 1.8 1 0 0 1 1 1 1 CHAP domain MG4 PF17789.1 KEZ37598.1 - 0.017 15.2 0.1 0.048 13.8 0.1 1.7 1 1 0 1 1 1 0 Macroglobulin domain MG4 DUF1175 PF06672.11 KEZ37598.1 - 0.1 12.3 0.0 2 8.0 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1175) Sortase PF04203.13 KEZ37599.1 - 1.1e-17 64.0 0.0 1.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Sortase domain JSRP PF15312.6 KEZ37599.1 - 0.013 15.4 0.0 0.063 13.2 0.1 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein MMR_HSR1 PF01926.23 KEZ37601.1 - 6.7e-47 158.3 0.0 7.9e-24 83.9 0.0 2.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 KEZ37601.1 - 2.3e-25 88.7 0.0 4.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 KEZ37601.1 - 1.2e-20 73.6 0.0 3.7e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KEZ37601.1 - 5.3e-19 68.5 0.2 5.8e-07 29.3 0.2 4.8 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEZ37601.1 - 2.5e-12 47.2 0.1 0.0031 17.6 0.0 4.0 2 2 1 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 KEZ37601.1 - 4.5e-11 42.9 0.0 0.078 12.9 0.0 3.6 4 0 0 4 4 4 3 RsgA GTPase AIG1 PF04548.16 KEZ37601.1 - 2.3e-10 40.2 0.0 3.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 AIG1 family Ras PF00071.22 KEZ37601.1 - 1.2e-05 25.0 0.0 0.08 12.5 0.0 2.8 2 1 0 2 2 2 2 Ras family AAA_16 PF13191.6 KEZ37601.1 - 1.4e-05 25.5 1.8 0.01 16.2 0.1 2.5 1 1 1 2 2 2 2 AAA ATPase domain Roc PF08477.13 KEZ37601.1 - 2.7e-05 24.4 0.1 0.28 11.4 0.1 3.2 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KEZ37601.1 - 0.00024 20.8 0.6 4.3 6.9 0.0 3.7 3 1 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KEZ37601.1 - 0.00024 20.6 0.0 0.059 12.8 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KEZ37601.1 - 0.00039 20.9 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 KEZ37601.1 - 0.00068 19.9 0.2 1.9 8.7 0.0 3.2 2 2 2 4 4 3 2 AAA domain AAA_33 PF13671.6 KEZ37601.1 - 0.0046 17.1 0.8 0.036 14.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KEZ37601.1 - 0.0072 15.3 1.9 3.3 6.6 0.2 3.3 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 KEZ37601.1 - 0.0079 15.6 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Ploopntkinase3 PF18751.1 KEZ37601.1 - 0.0082 16.1 0.3 0.25 11.2 0.3 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 KEZ37601.1 - 0.011 16.0 0.0 1.2 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEZ37601.1 - 0.011 15.6 0.1 0.74 9.7 0.0 2.6 2 1 0 2 2 2 0 NTPase AAA_24 PF13479.6 KEZ37601.1 - 0.011 15.4 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEZ37601.1 - 0.032 13.4 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Arf PF00025.21 KEZ37601.1 - 0.034 13.6 0.0 1.5 8.2 0.0 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family RNA_helicase PF00910.22 KEZ37601.1 - 0.041 14.3 0.0 6.4 7.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 KEZ37601.1 - 0.058 13.1 0.0 38 4.0 0.0 3.7 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KEZ37601.1 - 0.073 12.8 0.1 11 5.8 0.0 2.8 2 1 1 3 3 3 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KEZ37601.1 - 0.14 12.0 0.0 5.7 6.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KEZ37601.1 - 0.2 11.6 0.0 42 4.0 0.0 3.3 4 0 0 4 4 4 0 NACHT domain ATP_bind_1 PF03029.17 KEZ37601.1 - 0.21 11.3 0.0 84 2.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GBP PF02263.19 KEZ37601.1 - 0.23 10.7 0.0 11 5.2 0.0 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain VbhA PF18495.1 KEZ37601.1 - 0.82 9.6 8.4 0.67 9.9 0.7 3.6 2 1 1 3 3 3 0 Antitoxin VbhA Acyltransferase PF01553.21 KEZ37602.1 - 2.1e-16 59.8 0.0 2.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Cytidylate_kin PF02224.18 KEZ37603.1 - 2.4e-67 226.8 3.6 2.8e-67 226.5 3.6 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 KEZ37603.1 - 2.9e-09 37.3 0.7 9.2e-09 35.7 0.7 1.7 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 KEZ37603.1 - 1.7e-07 31.8 0.0 3e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KEZ37603.1 - 9e-06 25.9 0.1 0.00034 20.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.6 KEZ37603.1 - 1.2e-05 25.8 0.1 3.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ37603.1 - 0.0001 22.5 0.0 0.00029 21.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ37603.1 - 0.00021 21.7 1.0 0.00036 21.0 1.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEZ37603.1 - 0.00032 20.7 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KEZ37603.1 - 0.0029 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ADK PF00406.22 KEZ37603.1 - 0.0035 17.4 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_22 PF13401.6 KEZ37603.1 - 0.0052 17.1 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ37603.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KEZ37603.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ37603.1 - 0.039 14.2 0.2 0.11 12.7 0.1 1.9 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 KEZ37603.1 - 0.061 13.4 0.2 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 KEZ37603.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 KEZ37603.1 - 0.085 13.4 0.0 0.27 11.7 0.0 1.8 2 1 0 2 2 2 0 ABC transporter ParA PF10609.9 KEZ37603.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Viral_helicase1 PF01443.18 KEZ37603.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KEZ37603.1 - 0.2 11.5 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KEZ37603.1 - 1.1 9.0 7.1 1.4 8.6 2.7 2.3 1 1 1 2 2 2 0 AAA domain PDH PF02153.17 KEZ37604.1 - 2.6e-40 138.1 0.0 3.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase 3HCDH_N PF02737.18 KEZ37604.1 - 2.6e-05 24.2 0.8 0.0002 21.3 0.4 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEZ37604.1 - 0.00051 19.7 0.9 0.00074 19.1 0.2 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ37604.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_6 PF13740.6 KEZ37604.1 - 0.036 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 ACT domain ACT PF01842.25 KEZ37604.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain NAD_binding_2 PF03446.15 KEZ37604.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ37604.1 - 0.16 12.6 0.3 0.52 10.9 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PseudoU_synth_2 PF00849.22 KEZ37605.1 - 3e-16 59.9 0.0 5.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KEZ37605.1 - 1.7e-12 46.8 0.7 4.3e-12 45.6 0.7 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KEZ37605.1 - 0.013 15.3 0.2 0.026 14.3 0.2 1.5 1 0 0 1 1 1 0 S4 domain SMC_ScpB PF04079.16 KEZ37606.1 - 1.5e-54 183.9 0.0 1.7e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_15 PF12324.8 KEZ37606.1 - 0.0033 17.4 2.0 0.026 14.5 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase HTH_IclR PF09339.10 KEZ37606.1 - 0.01 15.6 0.6 0.63 9.9 0.2 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain SMC_ScpA PF02616.14 KEZ37607.1 - 4.3e-44 151.2 0.0 6.2e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Segregation and condensation protein ScpA Peptidase_M50 PF02163.22 KEZ37608.1 - 0.073 12.3 0.2 0.073 12.3 0.2 2.5 2 1 1 3 3 3 0 Peptidase family M50 AAA_31 PF13614.6 KEZ37609.1 - 2.9e-58 196.7 0.0 3.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ37609.1 - 4.7e-24 84.9 0.2 1.8e-13 50.7 0.1 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KEZ37609.1 - 2.6e-12 46.7 0.0 1.9e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KEZ37609.1 - 2.1e-09 37.2 0.0 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 KEZ37609.1 - 2e-08 33.8 0.1 0.0056 16.0 0.0 2.1 2 0 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.15 KEZ37609.1 - 3.3e-06 26.5 0.1 7.1e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 KEZ37609.1 - 5.9e-06 25.9 0.1 2.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 KEZ37609.1 - 0.00025 20.4 0.1 0.00065 19.1 0.0 1.6 2 0 0 2 2 2 1 VirC1 protein ADH_N PF08240.12 KEZ37610.1 - 4.9e-25 87.5 0.1 4.9e-25 87.5 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ37610.1 - 8.6e-25 87.2 0.0 1.5e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ37610.1 - 6.9e-08 33.6 0.0 1.1e-07 32.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ37610.1 - 0.00053 19.5 0.3 0.0047 16.4 0.2 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Urocanase PF01175.18 KEZ37610.1 - 0.025 14.2 0.4 0.043 13.4 0.4 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain zf-CXXC PF02008.20 KEZ37610.1 - 0.68 10.0 5.4 0.89 9.6 1.3 2.2 2 0 0 2 2 2 0 CXXC zinc finger domain Lactamase_B PF00753.27 KEZ37611.1 - 7.1e-19 68.6 10.2 1e-18 68.1 10.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Transgly_assoc PF04226.13 KEZ37612.1 - 2e-06 28.0 10.3 2e-06 28.0 10.3 1.7 2 0 0 2 2 2 1 Transglycosylase associated protein DUF543 PF04418.12 KEZ37612.1 - 0.08 12.9 2.2 0.14 12.2 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF543) DUF1576 PF07613.11 KEZ37612.1 - 0.25 10.8 3.9 0.33 10.5 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1576) 7TMR-DISM_7TM PF07695.11 KEZ37612.1 - 0.45 10.4 7.0 0.51 10.2 7.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Pkinase PF00069.25 KEZ37613.1 - 7.2e-38 130.5 0.0 9.6e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ37613.1 - 3.5e-17 62.5 0.0 4.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ37613.1 - 4.6e-06 26.7 12.1 0.00019 21.4 0.0 3.3 2 2 2 4 4 4 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ37613.1 - 0.004 16.0 0.0 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEZ37613.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KEZ37613.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3040 PF11239.8 KEZ37613.1 - 1.3 9.4 4.2 3.8 7.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) 4HBT PF03061.22 KEZ37614.1 - 4.4e-07 30.2 0.1 7.5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily LapA_dom PF06305.11 KEZ37615.1 - 1.5e-09 37.5 0.2 1.5e-09 37.5 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain SUR7 PF06687.12 KEZ37615.1 - 0.11 12.2 1.0 0.12 12.0 1.0 1.0 1 0 0 1 1 1 0 SUR7/PalI family PhdYeFM_antitox PF02604.19 KEZ37616.1 - 1.6e-14 53.5 1.1 1.8e-14 53.3 1.1 1.0 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system ParE_toxin PF05016.15 KEZ37617.1 - 1.1e-11 45.1 1.6 1.3e-11 44.9 1.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Gp49 PF05973.14 KEZ37617.1 - 5.8e-05 23.1 0.1 7.1e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) ParE-like_toxin PF15781.5 KEZ37617.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system HTH_3 PF01381.22 KEZ37618.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ37618.1 - 1.6e-06 28.3 0.3 2.2e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KEZ37618.1 - 0.00041 20.3 0.1 0.00047 20.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain His_Phos_1 PF00300.22 KEZ37621.1 - 2.8e-54 183.8 0.2 6e-54 182.7 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RVT_3 PF13456.6 KEZ37621.1 - 5.6e-22 77.9 0.0 8.6e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 KEZ37621.1 - 1.3e-10 41.7 0.0 2.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RING_7 PF02591.15 KEZ37622.1 - 1.5e-12 47.5 2.7 5.8e-12 45.6 2.7 2.1 1 0 0 1 1 1 1 C4-type zinc ribbon domain HalX PF08663.10 KEZ37622.1 - 0.00012 22.3 5.7 0.00012 22.3 5.7 3.2 1 1 1 3 3 3 1 HalX domain ABC_tran_CTD PF16326.5 KEZ37622.1 - 0.00019 21.6 7.8 0.01 16.1 2.5 2.7 1 1 1 2 2 2 2 ABC transporter C-terminal domain Spc7 PF08317.11 KEZ37622.1 - 0.00022 20.2 3.2 0.00028 19.9 3.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KEZ37622.1 - 0.0003 21.0 6.4 0.26 11.5 0.7 3.0 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KEZ37622.1 - 0.0017 18.9 2.8 0.0023 18.4 2.8 1.2 1 0 0 1 1 1 1 Fez1 ATG16 PF08614.11 KEZ37622.1 - 0.002 18.4 11.3 0.0069 16.6 9.0 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) FPP PF05911.11 KEZ37622.1 - 0.0034 15.7 0.1 0.0035 15.6 0.1 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 KEZ37622.1 - 0.005 16.2 7.0 0.0091 15.4 3.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KEZ37622.1 - 0.0051 16.9 1.5 0.29 11.2 1.4 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus FmiP_Thoc5 PF09766.9 KEZ37622.1 - 0.0073 15.6 0.4 0.013 14.8 0.1 1.5 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 Rab5-bind PF09311.11 KEZ37622.1 - 0.016 14.6 2.0 0.022 14.1 2.0 1.2 1 0 0 1 1 1 0 Rabaptin-like protein DivIC PF04977.15 KEZ37622.1 - 0.017 14.9 7.2 0.98 9.2 1.2 3.5 3 1 0 3 3 3 0 Septum formation initiator Baculo_PEP_C PF04513.12 KEZ37622.1 - 0.021 14.9 0.8 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 KEZ37622.1 - 0.024 13.7 0.8 1.1 8.3 0.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 ACP_PD PF04336.12 KEZ37622.1 - 0.039 14.4 0.2 0.085 13.3 0.2 1.7 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase CENP-F_leu_zip PF10473.9 KEZ37622.1 - 0.1 12.6 6.5 0.11 12.5 3.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 KEZ37622.1 - 0.19 12.2 1.3 20 5.8 0.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KEZ37622.1 - 0.24 11.5 4.2 1.3 9.1 0.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.22 KEZ37622.1 - 0.26 11.6 4.8 7.6 6.8 4.6 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 KEZ37622.1 - 0.39 10.8 7.7 1.6 8.8 1.0 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 KEZ37622.1 - 0.39 11.0 17.8 2.8 8.3 8.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) HIP1_clath_bdg PF16515.5 KEZ37622.1 - 0.42 11.2 6.6 1.4 9.5 4.7 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 KEZ37622.1 - 1.3 9.5 7.6 1.6 9.2 0.6 2.6 1 1 2 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 KEZ37622.1 - 1.6 9.0 7.1 31 4.9 0.2 3.6 4 0 0 4 4 3 0 Homeobox associated leucine zipper FUSC PF04632.12 KEZ37622.1 - 2.2 6.7 13.2 4.7 5.6 13.1 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family CLZ PF16526.5 KEZ37622.1 - 3.3 8.2 7.3 25 5.3 1.2 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 KEZ37622.1 - 3.4 8.0 5.9 35 4.7 0.8 3.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 KEZ37622.1 - 9.9 6.7 13.2 59 4.2 0.5 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) NIF3 PF01784.18 KEZ37623.1 - 3.6e-66 223.3 0.0 4.5e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Mur_ligase PF01225.25 KEZ37623.1 - 0.12 12.8 1.7 5.3 7.4 0.2 2.9 2 1 0 2 2 2 0 Mur ligase family, catalytic domain Peptidase_M7 PF02031.16 KEZ37624.1 - 0.0016 18.6 0.1 0.0043 17.2 0.1 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_5 PF13688.6 KEZ37624.1 - 0.002 18.3 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KEZ37624.1 - 0.092 12.6 0.7 0.21 11.5 0.7 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LON_substr_bdg PF02190.16 KEZ37626.1 - 8.5e-29 100.9 0.0 1e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF2065 PF09838.9 KEZ37626.1 - 0.03 14.3 0.2 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) FtsX PF02687.21 KEZ37627.1 - 0.22 12.0 7.5 2 8.9 2.2 2.3 1 1 1 2 2 2 0 FtsX-like permease family ABC2_membrane PF01061.24 KEZ37628.1 - 5.8e-13 48.7 7.3 8.2e-13 48.3 7.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ37628.1 - 1.7e-06 27.4 11.3 2.1e-06 27.1 11.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KEZ37629.1 - 2.7e-25 89.5 0.0 3.8e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ37629.1 - 1.4e-12 48.0 0.0 7.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ37629.1 - 4.8e-07 29.4 0.0 0.00035 20.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ37629.1 - 0.00016 22.1 0.1 0.0003 21.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ37629.1 - 0.0022 18.3 0.0 0.0075 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KEZ37629.1 - 0.011 16.2 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEZ37629.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KEZ37629.1 - 0.019 15.1 0.1 0.044 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ37629.1 - 0.021 14.6 0.2 0.046 13.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ37629.1 - 0.071 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KEZ37629.1 - 0.084 13.0 0.1 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KEZ37629.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KEZ37629.1 - 0.11 12.2 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KEZ37629.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEZ37629.1 - 0.29 11.0 0.0 1.3 8.9 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PseudoU_synth_2 PF00849.22 KEZ37632.1 - 2.8e-31 108.8 0.0 3.9e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KEZ37632.1 - 0.0021 17.7 0.1 0.0044 16.7 0.1 1.6 1 0 0 1 1 1 1 S4 domain Peptidase_A8 PF01252.18 KEZ37633.1 - 4e-29 101.7 0.5 4.9e-29 101.4 0.5 1.1 1 0 0 1 1 1 1 Signal peptidase (SPase) II ATPase_gene1 PF09527.10 KEZ37633.1 - 0.0095 16.1 0.1 0.0095 16.1 0.1 2.0 2 0 0 2 2 2 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4407 PF14362.6 KEZ37633.1 - 3.3 7.0 4.8 4.8 6.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_1 PF00133.22 KEZ37634.1 - 1.6e-166 555.1 0.0 4.4e-166 553.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEZ37634.1 - 3.1e-31 108.4 0.0 4.8e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KEZ37634.1 - 2.6e-10 39.6 0.1 0.0095 14.7 0.0 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) GP52 PF17468.2 KEZ37634.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 Phage gene product 52 tRNA-synt_1e PF01406.19 KEZ37634.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 KEZ37634.1 - 0.19 11.2 0.0 0.99 8.9 0.0 1.9 1 1 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DivIVA PF05103.13 KEZ37635.1 - 8.4e-20 71.2 14.5 5.3e-12 46.0 0.1 3.3 3 0 0 3 3 3 2 DivIVA protein FlxA PF14282.6 KEZ37635.1 - 0.0075 16.2 2.2 0.022 14.8 2.2 1.7 1 0 0 1 1 1 1 FlxA-like protein DUF4407 PF14362.6 KEZ37635.1 - 0.077 12.3 13.1 0.19 11.1 13.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 KEZ37635.1 - 0.12 13.2 0.4 0.12 13.2 0.4 3.2 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain FapA PF03961.13 KEZ37635.1 - 0.17 10.5 0.1 3 6.3 0.0 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A ISG65-75 PF11727.8 KEZ37635.1 - 0.27 10.5 2.9 5.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Csm1_N PF18504.1 KEZ37635.1 - 0.48 10.8 5.6 2.3 8.6 0.2 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain Herpes_BLRF2 PF05812.12 KEZ37635.1 - 0.6 10.3 3.8 0.34 11.1 0.8 2.2 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein KASH_CCD PF14662.6 KEZ37635.1 - 0.8 9.5 7.6 0.13 12.1 1.4 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TFIIA PF03153.13 KEZ37635.1 - 3.3 7.6 6.1 4.4 7.2 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3391 PF11871.8 KEZ37635.1 - 3.3 8.2 6.6 3.8 8.0 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) UPF0242 PF06785.11 KEZ37635.1 - 4.4 7.4 9.1 2.6 8.1 1.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YlqD PF11068.8 KEZ37635.1 - 4.6 7.6 13.1 0.58 10.5 0.9 2.6 2 1 0 2 2 2 0 YlqD protein Pox_A_type_inc PF04508.12 KEZ37635.1 - 4.9 7.2 8.5 2.5 8.1 2.8 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat GCN5L1 PF06320.13 KEZ37635.1 - 6.2 7.0 7.2 0.54 10.4 1.2 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) YabA PF06156.13 KEZ37635.1 - 8.3 7.1 6.2 43 4.8 2.9 2.9 2 2 0 2 2 2 0 Initiation control protein YabA KfrA_N PF11740.8 KEZ37635.1 - 9.5 6.9 34.5 19 5.9 14.2 3.6 1 1 3 4 4 4 0 Plasmid replication region DNA-binding N-term YGGT PF02325.17 KEZ37636.1 - 5.7e-11 42.7 11.7 6.7e-11 42.5 11.7 1.1 1 0 0 1 1 1 1 YGGT family SepF PF04472.12 KEZ37637.1 - 4.9e-28 97.2 0.0 7.3e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Cell division protein SepF Ala_racemase_N PF01168.20 KEZ37638.1 - 9.2e-18 64.7 0.0 1.9e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Cu-oxidase_4 PF02578.15 KEZ37639.1 - 1.9e-66 224.0 0.2 2.1e-66 223.8 0.2 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Tubulin PF00091.25 KEZ37640.1 - 1e-36 127.0 0.1 1.4e-36 126.5 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KEZ37640.1 - 2.1e-35 120.9 2.4 4.1e-35 120.0 2.4 1.5 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Mur_ligase PF01225.25 KEZ37641.1 - 8.9e-19 67.6 0.0 2e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 KEZ37641.1 - 3.9e-17 62.9 0.0 7.6e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEZ37641.1 - 2.5e-16 59.7 0.0 1e-15 57.7 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain F420H2_quin_red PF04075.14 KEZ37642.1 - 2.6e-33 114.9 0.5 3.2e-33 114.6 0.5 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF447 PF04289.12 KEZ37642.1 - 0.1 12.4 0.0 0.39 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 KEZ37642.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Glyco_tran_28_C PF04101.16 KEZ37643.1 - 7.1e-35 120.4 0.0 9.6e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 KEZ37643.1 - 1.8e-33 115.5 0.0 3.4e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.6 KEZ37643.1 - 5e-07 30.3 7.7 5e-07 30.3 7.7 3.5 1 1 2 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ37643.1 - 0.00017 21.6 1.5 0.00095 19.2 0.2 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 FTSW_RODA_SPOVE PF01098.19 KEZ37644.1 - 9.1e-104 347.3 18.6 1.1e-103 347.0 18.6 1.0 1 0 0 1 1 1 1 Cell cycle protein Mur_ligase_M PF08245.12 KEZ37645.1 - 1.9e-25 90.0 0.0 2.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Pyr_redox PF00070.27 KEZ37645.1 - 0.0011 19.5 0.3 0.0031 18.0 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ37645.1 - 0.0025 17.1 2.4 0.0041 16.4 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEZ37645.1 - 0.0037 16.6 0.9 0.009 15.3 0.9 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KEZ37645.1 - 0.0069 16.6 2.6 0.0069 16.6 2.6 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ37645.1 - 0.016 14.8 9.1 0.059 12.9 8.9 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KEZ37645.1 - 0.023 14.0 0.6 0.032 13.5 0.6 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Mur_ligase PF01225.25 KEZ37645.1 - 0.029 14.7 0.0 0.13 12.6 0.0 2.1 1 1 0 1 1 1 0 Mur ligase family, catalytic domain NAD_binding_7 PF13241.6 KEZ37645.1 - 0.036 14.5 0.1 0.098 13.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding LSDAT_prok PF18171.1 KEZ37645.1 - 0.041 13.1 0.2 0.076 12.2 0.2 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote HI0933_like PF03486.14 KEZ37645.1 - 0.078 11.7 0.2 0.14 10.8 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ37645.1 - 0.13 11.5 5.0 0.073 12.3 0.9 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transketolase_C PF02780.20 KEZ37645.1 - 0.45 10.4 2.3 51 3.8 0.1 3.3 3 0 0 3 3 3 0 Transketolase, C-terminal domain Glycos_transf_4 PF00953.21 KEZ37646.1 - 1.1e-37 129.5 12.2 1.1e-37 129.5 12.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 KEZ37646.1 - 2.7e-05 23.4 3.4 9.8e-05 21.7 3.4 2.1 1 0 0 1 1 1 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DUF4271 PF14093.6 KEZ37646.1 - 1.7 8.5 6.3 1.4 8.8 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) Mur_ligase_M PF08245.12 KEZ37647.1 - 4.6e-37 127.9 0.0 6.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEZ37647.1 - 2.3e-20 72.7 1.0 9.9e-19 67.4 0.1 3.4 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 KEZ37647.1 - 5.5e-12 45.8 1.6 2.9e-11 43.5 0.9 2.6 2 1 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 KEZ37648.1 - 7.4e-45 153.3 0.0 1.4e-44 152.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KEZ37648.1 - 4.9e-22 78.0 0.0 6.9e-21 74.3 0.0 2.8 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 KEZ37648.1 - 1.5e-08 34.9 0.7 4e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Methyltransf_24 PF13578.6 KEZ37648.1 - 0.14 13.2 1.1 3.8 8.6 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Transpeptidase PF00905.22 KEZ37649.1 - 1.8e-80 270.5 0.0 2.1e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 KEZ37649.1 - 4.4e-17 63.0 0.5 2.5e-16 60.5 0.1 2.2 2 1 0 2 2 2 1 Penicillin-binding Protein dimerisation domain Methyltransf_5 PF01795.19 KEZ37651.1 - 1e-102 343.8 0.0 1.1e-102 343.7 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 KEZ37651.1 - 0.014 16.1 0.0 0.033 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ37651.1 - 0.064 12.8 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DUF5594 PF18057.1 KEZ37651.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5594) Methyltransf_31 PF13847.6 KEZ37651.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain CTXphi_pIII-N1 PF16710.5 KEZ37651.1 - 0.24 11.5 0.0 0.47 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII MraZ PF02381.18 KEZ37652.1 - 4e-37 126.0 0.0 4e-18 65.2 0.0 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like MazE_antitoxin PF04014.18 KEZ37652.1 - 0.028 14.3 0.0 0.65 10.0 0.0 2.2 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin AAA_3 PF07726.11 KEZ37653.1 - 2.2e-61 205.5 0.0 3.7e-61 204.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KEZ37653.1 - 1.6e-20 72.7 2.4 3.7e-20 71.5 2.4 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 KEZ37653.1 - 1e-14 54.7 0.0 2.2e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KEZ37653.1 - 1e-06 29.2 0.0 4.6e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KEZ37653.1 - 1.8e-05 24.2 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 KEZ37653.1 - 3.2e-05 23.1 0.0 6.4e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 KEZ37653.1 - 0.00042 20.1 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 KEZ37653.1 - 0.0006 19.6 0.1 0.0046 16.7 0.1 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEZ37653.1 - 0.035 14.5 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_2 PF07724.14 KEZ37653.1 - 0.052 13.7 0.0 0.25 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KEZ37653.1 - 0.061 13.9 0.0 0.15 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ37653.1 - 0.17 12.2 0.0 0.5 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF58 PF01882.18 KEZ37654.1 - 1.9e-19 69.7 0.1 4e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 Collagen PF01391.18 KEZ37654.1 - 0.01 15.6 12.5 0.02 14.6 12.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF11 PF01345.18 KEZ37654.1 - 0.04 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 Transglut_core PF01841.19 KEZ37655.1 - 1.7e-27 96.1 0.0 3.4e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 KEZ37655.1 - 0.0074 16.5 4.5 0.0074 16.5 4.5 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) DUF3040 PF11239.8 KEZ37656.1 - 1.4e-25 89.3 2.3 2.1e-25 88.8 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) MerC PF03203.14 KEZ37656.1 - 0.016 15.6 0.1 0.018 15.5 0.1 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein Reticulon PF02453.17 KEZ37656.1 - 0.064 13.2 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Reticulon HCO3_cotransp PF00955.21 KEZ37656.1 - 0.33 9.7 4.2 0.43 9.3 4.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family Methyltransf_11 PF08241.12 KEZ37657.1 - 2.6e-15 56.8 0.1 5.5e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ37657.1 - 5.5e-15 55.9 0.1 1.7e-14 54.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ37657.1 - 1.7e-13 51.2 0.0 3.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ37657.1 - 2.9e-12 46.6 0.0 4.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ37657.1 - 4.8e-09 36.3 0.0 6.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KEZ37657.1 - 0.00049 19.7 0.0 0.00067 19.3 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 KEZ37657.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KEZ37657.1 - 0.0083 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 KEZ37657.1 - 0.012 16.7 0.1 0.051 14.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain AAA_lid_3 PF17862.1 KEZ37657.1 - 0.02 14.7 1.4 0.53 10.1 0.0 3.2 3 0 0 3 3 3 0 AAA+ lid domain T2SSE_N PF05157.15 KEZ37657.1 - 0.085 13.1 0.3 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain HEPN_SAV_6107 PF18726.1 KEZ37659.1 - 1.7e-33 115.0 9.4 2.3e-33 114.6 9.4 1.2 1 0 0 1 1 1 1 SAV_6107-like HEPN BTAD PF03704.17 KEZ37661.1 - 1.3e-25 90.6 4.2 1.3e-25 90.6 4.2 3.0 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 KEZ37661.1 - 3.7e-15 56.0 16.3 4.3e-09 36.5 0.2 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ37661.1 - 8.7e-11 41.5 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Trans_reg_C PF00486.28 KEZ37661.1 - 1.1e-08 35.0 0.0 2.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_2 PF07719.17 KEZ37661.1 - 7.8e-08 31.9 3.8 2.2 8.6 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ37661.1 - 1.9e-05 24.2 0.0 3.2 7.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ37661.1 - 0.00013 21.5 2.4 0.009 15.4 0.1 2.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_21 PF09976.9 KEZ37661.1 - 0.00065 19.5 0.0 0.002 17.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain AAA_22 PF13401.6 KEZ37661.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ37661.1 - 0.011 16.1 3.4 0.022 15.1 0.9 3.1 2 1 0 2 2 2 0 AAA ATPase domain DUF5372 PF17342.2 KEZ37661.1 - 0.013 15.8 0.7 11 6.6 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5372) DUF89 PF01937.19 KEZ37661.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 NACHT PF05729.12 KEZ37661.1 - 0.096 12.6 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KEZ37661.1 - 0.18 11.3 4.6 0.13 11.8 0.2 2.9 3 0 0 3 3 3 0 AAA domain TPR_10 PF13374.6 KEZ37661.1 - 1.5 8.8 11.9 12 6.0 0.1 5.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ37661.1 - 1.6 8.9 3.8 29 5.0 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3291 PF11695.8 KEZ37662.1 - 0.0007 19.3 0.0 0.0048 16.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3291) ABM PF03992.16 KEZ37662.1 - 0.18 12.0 0.7 0.51 10.5 0.0 2.1 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase DAO PF01266.24 KEZ37663.1 - 5.9e-20 72.1 9.1 1.6e-19 70.8 9.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ37663.1 - 5.9e-06 26.8 3.4 0.024 15.2 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KEZ37663.1 - 3.3e-05 23.3 0.0 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KEZ37663.1 - 5.8e-05 22.3 1.7 0.0019 17.4 0.9 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ37663.1 - 6.1e-05 22.4 0.3 0.0024 17.2 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ37663.1 - 9.6e-05 21.8 0.2 0.027 13.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ37663.1 - 0.00097 19.3 0.2 0.0044 17.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh PF00389.30 KEZ37663.1 - 0.003 17.2 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 KEZ37663.1 - 0.0096 15.8 0.5 0.019 14.9 0.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KEZ37663.1 - 0.015 14.1 0.2 0.43 9.2 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KEZ37663.1 - 0.036 13.4 0.4 0.079 12.2 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KEZ37663.1 - 0.068 13.3 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mqo PF06039.15 KEZ37663.1 - 0.14 10.7 1.0 6.5 5.2 0.0 2.8 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Acetyltransf_1 PF00583.25 KEZ37664.1 - 2.7e-07 30.8 0.0 3.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ37664.1 - 3.1e-05 24.3 0.0 4.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ37664.1 - 0.0044 17.0 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ37664.1 - 0.0067 16.5 0.0 1.7 8.7 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Caroten_synth PF04240.12 KEZ37665.1 - 4.2e-38 131.3 18.6 6.2e-38 130.8 18.6 1.2 1 0 0 1 1 1 1 Carotenoid biosynthesis protein Glycos_transf_2 PF00535.26 KEZ37666.1 - 4.8e-19 68.8 0.0 6.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ37666.1 - 7.4e-14 52.2 0.2 1.5e-13 51.2 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ37666.1 - 2.1e-09 37.1 0.1 3.5e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KEZ37666.1 - 6.7e-05 23.3 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KEZ37666.1 - 7.4e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 KEZ37666.1 - 0.0051 16.3 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Amino_oxidase PF01593.24 KEZ37667.1 - 6.8e-19 68.5 1.9 1e-17 64.6 0.3 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ37667.1 - 1.1e-13 51.2 0.5 6.7e-13 48.7 0.5 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ37667.1 - 7.4e-10 38.5 0.3 2.1e-05 23.9 1.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ37667.1 - 2.3e-09 37.7 0.2 0.00028 21.4 0.7 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ37667.1 - 5.3e-09 36.1 12.0 0.00019 21.2 1.6 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ37667.1 - 5.8e-07 28.9 5.0 9e-07 28.3 2.9 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEZ37667.1 - 1.6e-05 23.8 0.3 0.00015 20.6 1.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KEZ37667.1 - 0.00012 21.1 2.7 0.017 14.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KEZ37667.1 - 0.00025 21.1 0.9 0.07 13.1 0.3 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KEZ37667.1 - 0.00049 19.4 1.5 0.00074 18.9 1.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEZ37667.1 - 0.0039 16.3 2.4 0.0059 15.7 2.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ37667.1 - 0.0074 15.7 5.2 0.0074 15.7 5.2 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ37667.1 - 0.0096 15.2 0.8 0.016 14.4 0.8 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KEZ37667.1 - 0.01 14.9 1.0 0.069 12.2 0.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KEZ37667.1 - 0.023 14.3 0.5 0.06 12.9 0.4 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KEZ37667.1 - 0.041 13.1 1.7 0.059 12.6 1.7 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KEZ37667.1 - 0.097 12.3 0.6 0.16 11.6 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KEZ37667.1 - 0.18 11.0 0.2 0.29 10.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEZ37667.1 - 0.2 11.5 1.5 0.31 10.9 1.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 KEZ37667.1 - 0.39 9.5 0.0 0.53 9.0 0.0 1.1 1 0 0 1 1 1 0 MCRA family CDP-OH_P_transf PF01066.21 KEZ37668.1 - 1.5e-07 32.0 0.7 1.5e-07 32.0 0.7 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MTHFR PF02219.17 KEZ37670.1 - 2.4e-99 332.3 0.0 2.7e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4097 PF13349.6 KEZ37671.1 - 8.5e-05 22.0 0.0 0.00058 19.3 0.0 2.2 1 1 2 3 3 3 1 Putative adhesin NucS PF01939.16 KEZ37671.1 - 0.053 12.9 0.1 0.11 11.8 0.1 1.4 2 0 0 2 2 2 0 Endonuclease NucS polyprenyl_synt PF00348.17 KEZ37672.1 - 1.3e-51 175.1 0.0 1.9e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Amino_oxidase PF01593.24 KEZ37673.1 - 7.3e-34 117.8 0.4 1.4e-33 116.9 0.4 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEZ37673.1 - 4.1e-15 56.2 4.8 2.3e-14 53.7 4.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ37673.1 - 3.7e-11 43.1 1.1 1.5e-10 41.2 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ37673.1 - 1.6e-07 30.9 1.8 0.00029 20.2 0.6 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ37673.1 - 6.2e-06 25.2 0.2 0.0049 15.6 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KEZ37673.1 - 1.2e-05 24.6 8.9 0.00018 20.7 4.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KEZ37673.1 - 1.6e-05 25.4 2.8 0.00095 19.7 1.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ37673.1 - 0.00027 20.3 2.6 0.00052 19.4 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ37673.1 - 0.00031 20.0 0.3 0.0005 19.4 0.3 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KEZ37673.1 - 0.002 18.1 6.3 0.48 10.4 1.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ37673.1 - 0.0048 16.0 4.2 0.0074 15.4 1.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEZ37673.1 - 0.019 14.2 0.3 0.057 12.7 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ37673.1 - 0.037 13.4 6.9 0.47 9.7 5.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KEZ37673.1 - 0.047 13.0 1.4 0.46 9.8 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase AlaDh_PNT_C PF01262.21 KEZ37673.1 - 0.25 10.6 1.8 0.43 9.9 1.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEZ37673.1 - 2.3 7.2 4.8 0.63 9.1 1.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A AAA_3 PF07726.11 KEZ37674.1 - 8.4e-61 203.6 0.0 1.5e-60 202.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KEZ37674.1 - 1.8e-17 62.9 2.4 1.8e-17 62.9 2.4 2.2 1 1 1 2 2 2 1 AAA lid domain AAA_5 PF07728.14 KEZ37674.1 - 2.8e-14 53.3 0.0 5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KEZ37674.1 - 0.00021 21.7 0.0 0.0004 20.8 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 KEZ37674.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.3 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 KEZ37674.1 - 0.0013 18.4 0.1 0.0083 15.8 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KEZ37674.1 - 0.059 12.7 0.5 0.2 11.0 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KEZ37674.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF58 PF01882.18 KEZ37675.1 - 1.6e-14 53.9 0.7 3.3e-14 52.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 KEZ37676.1 - 2.3e-17 63.6 0.0 3.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ37676.1 - 8.5e-15 55.4 0.0 1.2e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 KEZ37676.1 - 2.4e-06 27.8 7.9 4.3e-06 27.0 7.9 1.4 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal VWA_3 PF13768.6 KEZ37676.1 - 9.1e-05 22.4 0.1 0.00052 20.0 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KEZ37676.1 - 0.00037 20.0 0.1 0.0066 15.9 0.0 2.1 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 KEZ37676.1 - 0.018 14.3 0.8 0.075 12.2 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1194) Ni_hydr_CYTB PF01292.20 KEZ37676.1 - 0.039 13.6 0.8 0.058 13.0 0.8 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 CysA_C_terminal PF17850.1 KEZ37676.1 - 0.088 13.4 0.9 2.5 8.7 0.2 2.6 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Ssl1 PF04056.14 KEZ37676.1 - 0.23 11.3 0.0 0.48 10.2 0.0 1.5 2 0 0 2 2 2 0 Ssl1-like SQS_PSY PF00494.19 KEZ37677.1 - 4.6e-65 219.7 3.5 5.5e-65 219.5 3.5 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase tRNA-synt_2b PF00587.25 KEZ37678.1 - 1.3e-28 100.2 0.0 1.9e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KEZ37678.1 - 3.4e-21 75.5 0.7 5e-21 74.9 0.7 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4763 PF15960.5 KEZ37678.1 - 0.074 12.3 0.4 0.16 11.3 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) KELK PF15796.5 KEZ37678.1 - 1.2 9.7 5.0 2.2 8.8 5.0 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ResIII PF04851.15 KEZ37680.1 - 8.4e-11 42.2 0.0 2.2e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KEZ37680.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PhoH PF02562.16 KEZ37680.1 - 0.004 16.6 0.1 0.0099 15.3 0.1 1.7 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 KEZ37680.1 - 0.014 15.2 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KEZ37680.1 - 0.015 15.5 0.0 0.046 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ37680.1 - 0.022 14.3 0.5 0.022 14.3 0.5 2.6 3 0 0 3 3 3 0 AAA domain Helicase_C PF00271.31 KEZ37680.1 - 0.048 14.0 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AAA PF00004.29 KEZ37680.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEZ37680.1 - 0.1 12.9 1.7 0.11 12.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 KEZ37680.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain HTH_19 PF12844.7 KEZ37681.1 - 0.0002 21.3 0.2 0.0002 21.3 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 KEZ37681.1 - 0.00071 19.9 1.9 0.00071 19.9 1.9 4.3 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ37681.1 - 0.0043 17.1 0.2 2 8.5 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix TAT_signal PF10518.9 KEZ37681.1 - 0.023 14.5 0.1 0.023 14.5 0.1 3.6 5 0 0 5 5 5 0 TAT (twin-arginine translocation) pathway signal sequence DUF2379 PF09543.10 KEZ37681.1 - 0.29 11.4 5.8 2.5 8.3 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) TPR_10 PF13374.6 KEZ37681.1 - 1.2 9.1 12.6 1.7 8.6 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CutA1 PF03091.15 KEZ37682.1 - 1.6e-33 114.5 0.0 1.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein HD_4 PF13328.6 KEZ37683.1 - 1.1e-43 148.6 0.8 1.1e-43 148.6 0.8 2.2 2 0 0 2 2 2 1 HD domain TGS PF02824.21 KEZ37683.1 - 2.3e-20 72.4 0.0 5.5e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain RelA_SpoT PF04607.17 KEZ37683.1 - 2.5e-19 69.7 0.0 4.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins ACT_4 PF13291.6 KEZ37683.1 - 1.6e-15 57.4 0.0 4.4e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain HD PF01966.22 KEZ37683.1 - 5.8e-09 36.2 0.5 5.8e-09 36.2 0.5 2.5 3 1 0 3 3 3 1 HD domain ACT PF01842.25 KEZ37683.1 - 1.8e-08 34.0 0.6 4.8e-08 32.6 0.2 2.0 2 0 0 2 2 2 1 ACT domain ThiS PF02597.20 KEZ37683.1 - 0.00026 21.6 0.2 0.013 16.1 0.0 3.2 3 0 0 3 3 3 1 ThiS family Mtd_N PF18454.1 KEZ37683.1 - 0.062 13.3 1.4 2 8.5 0.3 2.6 2 0 0 2 2 2 0 Major tropism determinant N-terminal domain Npun_R1517 PF18068.1 KEZ37683.1 - 0.12 12.8 0.3 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Npun R1517 HD_4 PF13328.6 KEZ37684.1 - 4.5e-47 159.7 4.9 8.3e-47 158.8 4.9 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 KEZ37684.1 - 6.4e-38 129.6 0.0 1.1e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 KEZ37684.1 - 4e-21 74.8 0.2 1.3e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.6 KEZ37684.1 - 6.4e-14 52.3 0.1 1.5e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 KEZ37684.1 - 5.7e-12 45.2 1.4 9.5e-12 44.5 0.5 2.0 2 0 0 2 2 2 1 ACT domain HD PF01966.22 KEZ37684.1 - 1e-08 35.5 1.5 1e-08 35.5 1.5 1.7 2 0 0 2 2 2 1 HD domain DNA_pol3_gamma3 PF12169.8 KEZ37684.1 - 0.022 14.6 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III ThiS PF02597.20 KEZ37684.1 - 0.11 13.1 0.0 0.46 11.1 0.0 2.1 1 0 0 1 1 1 0 ThiS family ACT_6 PF13740.6 KEZ37684.1 - 0.14 12.1 0.7 0.55 10.3 0.2 2.2 2 0 0 2 2 2 0 ACT domain Pribosyltran PF00156.27 KEZ37685.1 - 1.2e-16 60.7 0.3 1.8e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ37685.1 - 0.0022 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KEZ37685.1 - 0.17 11.4 0.1 0.75 9.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase SecD_SecF PF02355.16 KEZ37686.1 - 4.4e-62 208.8 7.9 4.4e-62 208.8 7.9 1.6 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 KEZ37686.1 - 7.6e-05 22.1 0.4 7.6e-05 22.1 0.4 2.0 2 0 0 2 2 2 1 SecD/SecF GG Motif DUF5337 PF17272.2 KEZ37686.1 - 0.036 13.9 1.4 0.17 11.7 1.4 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5337) SecD_SecF PF02355.16 KEZ37687.1 - 1.1e-09 38.0 10.0 1.5e-09 37.5 10.0 1.2 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 KEZ37687.1 - 0.00016 20.8 21.9 0.00027 20.0 21.9 1.3 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 KEZ37687.1 - 0.0072 15.8 0.0 0.031 13.8 0.0 2.0 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 KEZ37687.1 - 0.0074 14.0 10.6 0.011 13.5 10.6 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family BphX PF06139.12 KEZ37687.1 - 0.053 13.4 2.4 0.1 12.5 2.4 1.4 1 0 0 1 1 1 0 BphX-like YajC PF02699.15 KEZ37688.1 - 8.1e-17 60.9 0.0 1.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit TauE PF01925.19 KEZ37688.1 - 0.046 13.3 0.6 0.061 12.9 0.6 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE RuvB_N PF05496.12 KEZ37689.1 - 1.3e-73 246.0 0.1 2.8e-73 244.9 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 KEZ37689.1 - 1.5e-30 104.8 2.4 2.9e-30 103.8 2.4 1.5 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 KEZ37689.1 - 9.3e-23 79.9 0.0 1.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 KEZ37689.1 - 2.2e-16 60.5 0.0 4.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ37689.1 - 8.2e-08 32.8 1.6 7.5e-06 26.4 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEZ37689.1 - 2.4e-07 30.8 0.3 1.8e-05 24.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KEZ37689.1 - 9.9e-06 25.0 0.0 2.4e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KEZ37689.1 - 2.9e-05 23.6 0.4 0.027 13.9 0.0 2.5 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ37689.1 - 0.0026 17.5 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 KEZ37689.1 - 0.0054 16.6 0.0 0.078 12.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KEZ37689.1 - 0.02 14.0 0.0 0.072 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KEZ37689.1 - 0.021 15.1 0.1 2 8.7 0.0 2.7 2 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KEZ37689.1 - 0.031 14.3 0.0 0.077 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KEZ37689.1 - 0.034 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 KEZ37689.1 - 0.04 13.9 0.1 0.095 12.7 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KEZ37689.1 - 0.058 13.2 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ37689.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KEZ37689.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KEZ37689.1 - 0.21 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RuvA_N PF01330.21 KEZ37690.1 - 2.8e-18 65.8 0.0 4.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 RuvA N terminal domain HHH_5 PF14520.6 KEZ37690.1 - 7.8e-15 55.2 0.1 1.8e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KEZ37690.1 - 6.4e-07 28.9 0.8 0.033 14.1 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif RuvA_C PF07499.13 KEZ37690.1 - 1.7e-05 25.1 1.3 0.00034 21.0 0.7 2.5 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH_3 PF12836.7 KEZ37690.1 - 0.0031 17.8 0.1 0.55 10.5 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 KEZ37690.1 - 0.012 16.0 0.2 0.66 10.4 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif HHH_2 PF12826.7 KEZ37690.1 - 0.022 14.8 0.0 7.6 6.7 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix motif PG_binding_2 PF08823.11 KEZ37690.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain RuvC PF02075.17 KEZ37691.1 - 2.5e-50 170.2 0.1 2.8e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC Transcrip_reg PF01709.20 KEZ37692.1 - 2.1e-87 292.6 0.1 2.3e-87 292.4 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator T2SSM PF04612.12 KEZ37692.1 - 0.1 12.7 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M SNO PF01174.19 KEZ37693.1 - 3.8e-53 180.1 0.0 4.3e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KEZ37693.1 - 1.5e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KEZ37693.1 - 3e-05 23.8 0.0 4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KEZ37693.1 - 9.9e-05 22.2 0.0 0.00066 19.5 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KEZ37693.1 - 0.0022 17.8 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KEZ37693.1 - 0.0051 16.6 0.3 1.3 8.7 0.1 2.7 3 0 0 3 3 3 2 Peptidase C26 URO-D PF01208.17 KEZ37693.1 - 0.062 12.4 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) SOR_SNZ PF01680.17 KEZ37694.1 - 1.4e-105 351.6 6.0 1.8e-105 351.2 6.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KEZ37694.1 - 3e-10 39.8 7.1 8.6e-07 28.5 0.4 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KEZ37694.1 - 2e-05 23.8 0.2 0.089 11.9 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KEZ37694.1 - 0.00013 21.5 0.3 0.013 15.0 0.0 2.7 2 1 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 KEZ37694.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 KEZ37694.1 - 0.0021 17.3 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KEZ37694.1 - 0.0023 17.2 1.6 0.1 11.7 0.1 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KEZ37694.1 - 0.015 14.7 8.7 0.023 14.1 0.6 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Glu_synthase PF01645.17 KEZ37694.1 - 0.037 13.2 0.6 0.06 12.5 0.3 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase OMPdecase PF00215.24 KEZ37694.1 - 0.04 13.5 0.1 0.073 12.6 0.0 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Trp_syntA PF00290.20 KEZ37694.1 - 0.058 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain WhiA_N PF10298.9 KEZ37694.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain DHO_dh PF01180.21 KEZ37694.1 - 0.16 11.1 0.1 0.42 9.8 0.1 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase LemA PF04011.12 KEZ37695.1 - 0.14 12.0 0.1 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 LemA family PsaN PF05479.11 KEZ37695.1 - 1.7 8.8 4.7 0.22 11.7 0.4 1.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Glyco_trans_1_4 PF13692.6 KEZ37696.1 - 3e-33 115.1 0.6 3.2e-31 108.5 0.1 2.8 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ37696.1 - 2.9e-31 108.7 1.4 6.6e-31 107.6 1.2 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEZ37696.1 - 3.8e-26 91.7 0.0 6.6e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ37696.1 - 1.3e-21 77.7 8.7 1.3e-21 77.7 8.7 3.0 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ37696.1 - 3.8e-11 43.2 0.2 1.1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ37696.1 - 5.5e-08 32.9 0.0 9.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KEZ37696.1 - 0.021 14.5 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain Lip_A_acyltrans PF03279.13 KEZ37697.1 - 2e-53 181.5 0.0 2.4e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase CDP-OH_P_transf PF01066.21 KEZ37698.1 - 8.2e-09 36.1 1.8 8.2e-09 36.1 1.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FA_desaturase PF00487.24 KEZ37698.1 - 0.26 11.1 4.6 2.1 8.1 0.4 2.2 2 0 0 2 2 2 0 Fatty acid desaturase SCAMP PF04144.13 KEZ37698.1 - 0.47 10.7 0.1 0.47 10.7 0.1 2.5 3 0 0 3 3 3 0 SCAMP family EFG_IV PF03764.18 KEZ37699.1 - 8.7e-39 132.0 0.0 1.8e-38 131.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 KEZ37699.1 - 2.6e-26 92.3 0.0 3.3e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEZ37699.1 - 5e-25 87.3 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KEZ37699.1 - 8.3e-23 80.3 0.0 1.4e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KEZ37699.1 - 1.1e-07 32.2 0.0 2.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ37699.1 - 2.6e-05 24.3 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ37699.1 - 0.0013 19.1 0.0 0.0032 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KEZ37699.1 - 0.0052 16.1 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KEZ37699.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KEZ37699.1 - 0.04 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 KEZ37699.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KEZ37699.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ37699.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KEZ37699.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KEZ37699.1 - 0.16 12.5 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 KEZ37699.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ37699.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KEZ37699.1 - 0.22 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region HIT PF01230.23 KEZ37700.1 - 4e-12 46.7 0.0 5.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 KEZ37700.1 - 1.6e-07 31.2 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 KEZ37700.1 - 0.00063 20.2 0.0 0.00092 19.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SsgA PF04686.12 KEZ37702.1 - 1.7e-34 117.7 0.0 2.1e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA Chorismate_bind PF00425.18 KEZ37703.1 - 1.1e-71 241.5 0.0 1.4e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Amidase_3 PF01520.18 KEZ37704.1 - 4e-33 115.0 0.0 4.8e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase CBM_15 PF03426.14 KEZ37704.1 - 0.12 11.9 0.1 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 15) Bacillus_PapR PF05968.11 KEZ37704.1 - 6.8 6.7 6.0 17 5.4 6.0 1.6 1 0 0 1 1 1 0 Bacillus PapR protein DUF3097 PF11296.8 KEZ37705.1 - 1.9e-121 404.5 0.0 2.1e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) Isochorismatase PF00857.20 KEZ37706.1 - 2.4e-27 96.2 0.0 2.7e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF4193 PF13834.6 KEZ37707.1 - 1.7e-35 121.4 0.9 1.9e-35 121.3 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) DUF3145 PF11343.8 KEZ37708.1 - 2.1e-55 186.6 0.0 2.4e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) Band_7 PF01145.25 KEZ37709.1 - 2.9e-32 112.1 9.8 9.1e-32 110.5 9.8 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KEZ37709.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Flot PF15975.5 KEZ37709.1 - 0.5 10.6 6.1 2.1 8.6 6.0 2.0 1 1 0 1 1 1 0 Flotillin NfeD PF01957.18 KEZ37710.1 - 1.3e-20 73.5 1.0 1.3e-20 73.5 1.0 1.7 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding CBM_48 PF02922.18 KEZ37711.1 - 9.7e-21 73.9 0.0 3.1e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KEZ37711.1 - 8.5e-14 51.9 0.0 7.1e-06 25.8 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KEZ37711.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase PF00128.24 KEZ37712.1 - 1.9e-21 77.0 0.0 2.5e-16 60.1 0.0 3.4 4 0 0 4 4 4 3 Alpha amylase, catalytic domain Alpha-amylase PF00128.24 KEZ37713.1 - 1.2e-21 77.7 0.0 8.6e-14 51.8 0.0 3.1 2 1 0 3 3 3 3 Alpha amylase, catalytic domain DUF3459 PF11941.8 KEZ37713.1 - 6.7e-16 58.4 2.5 9.4e-16 57.9 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) CBM_48 PF02922.18 KEZ37713.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Toprim_C_rpt PF13368.6 KEZ37713.1 - 0.16 12.0 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat AFG1_ATPase PF03969.16 KEZ37714.1 - 2.4e-50 171.4 0.0 6.4e-34 117.4 0.0 2.6 2 1 1 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 KEZ37714.1 - 0.07 13.5 0.8 0.47 10.8 0.8 2.3 1 1 0 1 1 1 0 AAA ATPase domain RibD_C PF01872.17 KEZ37715.1 - 4.6e-33 114.7 0.0 6.4e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain DUF4380 PF14315.6 KEZ37716.1 - 0.074 12.0 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) GTP_EFTU PF00009.27 KEZ37718.1 - 1.7e-41 141.9 0.0 2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEZ37718.1 - 3.1e-07 30.5 0.0 3.6e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KEZ37718.1 - 0.00012 22.4 0.2 0.00041 20.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 cobW PF02492.19 KEZ37718.1 - 0.08 12.5 0.0 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PAPS_reduct PF01507.19 KEZ37719.1 - 5.4e-42 143.8 0.0 6.6e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Inositol_P PF00459.25 KEZ37720.1 - 5.4e-31 108.1 0.0 3.3e-30 105.5 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family APS_kinase PF01583.20 KEZ37721.1 - 6.4e-55 185.4 0.0 9.9e-55 184.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KEZ37721.1 - 4e-06 27.1 0.0 9.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP-sulfurylase PF01747.17 KEZ37721.1 - 1.3e-05 24.8 0.0 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 2 ATP-sulfurylase MeaB PF03308.16 KEZ37721.1 - 0.001 18.1 0.3 0.0034 16.4 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KEZ37721.1 - 0.0043 17.1 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KEZ37721.1 - 0.0081 16.7 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ37721.1 - 0.0094 16.4 0.1 0.023 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEZ37721.1 - 0.019 14.7 0.1 0.019 14.7 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KEZ37721.1 - 0.037 14.6 0.1 0.067 13.7 0.1 1.3 1 0 0 1 1 1 0 ABC transporter CLP1_P PF16575.5 KEZ37721.1 - 0.058 13.2 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 KEZ37721.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 KEZ37721.1 - 0.15 12.1 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain PUA_2 PF14306.6 KEZ37721.1 - 0.22 11.2 0.0 9.2 5.9 0.0 2.2 1 1 0 1 1 1 0 PUA-like domain Bac_transf PF02397.16 KEZ37722.1 - 2.2e-67 226.2 0.0 2.5e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase APS_kinase PF01583.20 KEZ37723.1 - 3.3e-55 186.3 0.0 4.6e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KEZ37723.1 - 2.5e-06 27.7 0.0 4.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KEZ37723.1 - 0.00048 19.2 0.3 0.002 17.2 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KEZ37723.1 - 0.0032 17.5 0.1 0.0047 17.0 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KEZ37723.1 - 0.005 17.4 0.0 0.0083 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ37723.1 - 0.0053 17.1 0.1 0.014 15.8 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEZ37723.1 - 0.0059 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEZ37723.1 - 0.023 15.2 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter CLP1_P PF16575.5 KEZ37723.1 - 0.035 13.9 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 KEZ37723.1 - 0.044 13.1 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATP-sulfurylase PF01747.17 KEZ37723.1 - 0.059 12.8 0.0 8.4 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP-sulfurylase DUF87 PF01935.17 KEZ37723.1 - 0.091 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain KTI12 PF08433.10 KEZ37723.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Bac_transf PF02397.16 KEZ37724.1 - 3e-66 222.5 0.0 4.8e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 KEZ37724.1 - 1.5e-11 44.6 0.2 3e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 CoA-binding domain Chlor_dismutase PF06778.12 KEZ37725.1 - 2.4e-69 232.8 0.0 2.8e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Chlorite dismutase Amino_oxidase PF01593.24 KEZ37726.1 - 6.8e-48 164.1 0.9 7.7e-48 163.9 0.9 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ37726.1 - 1.2e-10 41.4 0.5 3.3e-10 40.1 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ37726.1 - 7e-09 35.7 10.2 2.2e-06 27.5 4.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ37726.1 - 7.8e-05 22.0 0.3 0.00032 20.0 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ37726.1 - 8.5e-05 21.4 0.2 0.00015 20.6 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KEZ37726.1 - 0.0006 20.3 0.8 0.0015 19.0 0.8 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ37726.1 - 0.0018 17.6 0.7 0.0018 17.6 0.7 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KEZ37726.1 - 0.0046 16.1 4.2 0.0046 16.1 4.2 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ37726.1 - 0.011 15.0 1.4 0.018 14.3 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KEZ37726.1 - 0.021 14.1 0.4 0.021 14.1 0.4 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KEZ37726.1 - 0.024 14.6 0.9 0.58 10.1 0.5 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HTH_AsnC-type PF13404.6 KEZ37726.1 - 0.12 12.3 1.3 0.25 11.2 0.2 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KEZ37726.1 - 0.16 11.6 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Trp_halogenase PF04820.14 KEZ37726.1 - 0.18 10.6 1.6 0.28 10.0 1.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KEZ37726.1 - 0.2 10.9 0.1 5 6.3 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ37726.1 - 0.24 10.4 0.8 0.57 9.2 0.8 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KEZ37726.1 - 1.3 8.0 3.8 2.2 7.3 3.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ37726.1 - 7.3 5.8 9.6 0.087 12.2 2.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase URO-D PF01208.17 KEZ37727.1 - 3.8e-112 374.9 0.0 4.2e-112 374.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3817 PF12823.7 KEZ37728.1 - 4.5e-20 72.3 4.3 6.4e-20 71.8 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) DUF3000 PF11452.8 KEZ37730.1 - 3.8e-62 208.9 0.6 6.7e-62 208.1 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3000) DNA_pol_A_exo1 PF01612.20 KEZ37731.1 - 7.7e-33 113.7 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exoN PF18305.1 KEZ37731.1 - 3.4e-28 97.8 2.8 9.4e-28 96.3 2.8 1.8 1 0 0 1 1 1 1 3' to 5' exonuclease C-terminal domain HRDC PF00570.23 KEZ37731.1 - 4.9e-13 48.8 0.1 1.8e-12 47.0 0.1 2.0 1 0 0 1 1 1 1 HRDC domain Thiolase_N PF00108.23 KEZ37732.1 - 1.1e-52 179.0 0.0 1.5e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ37732.1 - 7.5e-34 116.0 3.7 8.1e-34 115.9 0.0 2.4 2 1 1 3 3 3 1 Thiolase, C-terminal domain 3HCDH_N PF02737.18 KEZ37733.1 - 3e-52 177.1 1.9 5.5e-52 176.3 1.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KEZ37733.1 - 1.8e-18 66.7 0.0 7.1e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KEZ37733.1 - 9e-16 58.3 0.0 1.4e-12 48.1 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KEZ37733.1 - 2.1e-09 37.3 0.0 2e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase LPG_synthase_TM PF03706.13 KEZ37735.1 - 1.2e-22 80.8 52.4 1.6e-22 80.4 52.4 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DXP_synthase_N PF13292.6 KEZ37736.1 - 3.6e-109 364.2 0.0 5.2e-109 363.7 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 KEZ37736.1 - 4.6e-37 127.4 0.0 2e-36 125.3 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ37736.1 - 2.3e-27 95.3 0.2 1.2e-26 93.0 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KEZ37736.1 - 9.5e-08 32.0 0.1 2.1e-05 24.3 0.1 3.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KEZ37736.1 - 1.2e-07 31.0 0.0 0.00012 21.1 0.0 2.2 2 0 0 2 2 2 2 Dehydrogenase E1 component Transketolase_N PF00456.21 KEZ37736.1 - 0.024 13.6 0.1 0.24 10.3 0.0 2.3 3 0 0 3 3 3 0 Transketolase, thiamine diphosphate binding domain PFOR_II PF17147.4 KEZ37736.1 - 0.057 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II HHH_5 PF14520.6 KEZ37736.1 - 0.11 13.1 0.1 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain tRNA_U5-meth_tr PF05958.11 KEZ37737.1 - 1.2e-08 34.3 0.0 4.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 KEZ37737.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 KEZ37737.1 - 0.0018 18.9 0.5 0.024 15.4 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KEZ37737.1 - 0.0038 17.0 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KEZ37737.1 - 0.0098 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KEZ37737.1 - 0.04 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NSs PF11073.8 KEZ37737.1 - 0.045 13.2 0.2 0.084 12.3 0.1 1.5 2 0 0 2 2 2 0 Rift valley fever virus non structural protein (NSs) like Cons_hypoth95 PF03602.15 KEZ37737.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_5 PF01795.19 KEZ37737.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family AA_permease_2 PF13520.6 KEZ37738.1 - 1e-29 103.7 29.5 1.4e-29 103.2 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease K_trans PF02705.16 KEZ37738.1 - 0.0062 15.1 10.1 0.0059 15.2 6.1 2.3 2 0 0 2 2 2 1 K+ potassium transporter DUF1887 PF09002.11 KEZ37738.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) TrkA_N PF02254.18 KEZ37739.1 - 3e-24 85.5 0.3 9.7e-24 83.9 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain TrkA_C PF02080.21 KEZ37739.1 - 2.9e-09 36.6 0.1 6.5e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 TrkA-C domain Sacchrp_dh_NADP PF03435.18 KEZ37739.1 - 9.2e-05 22.7 0.2 0.00023 21.4 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KEZ37739.1 - 0.00029 21.4 0.3 0.015 15.9 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEZ37739.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KEZ37739.1 - 0.001 19.6 0.1 0.003 18.1 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain Rossmann-like PF10727.9 KEZ37739.1 - 0.002 18.0 0.5 0.0056 16.5 0.1 1.9 2 0 0 2 2 2 1 Rossmann-like domain DAO PF01266.24 KEZ37739.1 - 0.0031 17.1 0.7 0.071 12.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEZ37739.1 - 0.0051 16.1 0.1 0.0093 15.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEZ37739.1 - 0.0074 16.2 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KEZ37739.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 KEZ37739.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KEZ37739.1 - 0.055 13.6 0.1 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KEZ37739.1 - 0.066 13.8 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KEZ37739.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 KEZ37739.1 - 0.41 10.5 3.4 0.53 10.2 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H-binding TrkA_N PF02254.18 KEZ37740.1 - 5.2e-26 91.2 0.2 1.9e-25 89.4 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain TrkA_C PF02080.21 KEZ37740.1 - 1.8e-13 50.1 2.6 6e-13 48.4 0.3 2.3 2 0 0 2 2 2 1 TrkA-C domain NAD_binding_7 PF13241.6 KEZ37740.1 - 9.8e-07 29.2 0.1 5.9e-06 26.7 0.1 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.17 KEZ37740.1 - 6.7e-06 26.6 0.1 1.8e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KEZ37740.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KEZ37740.1 - 3.5e-05 23.8 0.1 7.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding FAD_binding_3 PF01494.19 KEZ37740.1 - 0.0005 19.4 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KEZ37740.1 - 0.00056 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KEZ37740.1 - 0.00075 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KEZ37740.1 - 0.00086 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ37740.1 - 0.001 19.3 0.1 0.0022 18.3 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 KEZ37740.1 - 0.0015 18.6 0.1 0.0039 17.3 0.0 1.8 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DAO PF01266.24 KEZ37740.1 - 0.0036 16.9 0.1 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ37740.1 - 0.0039 17.7 0.0 0.0091 16.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KEZ37740.1 - 0.022 15.2 0.2 0.072 13.6 0.0 1.9 2 1 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KEZ37740.1 - 0.027 13.8 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KEZ37740.1 - 0.043 14.0 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KEZ37740.1 - 0.044 13.0 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KEZ37740.1 - 0.047 13.7 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 KEZ37740.1 - 0.057 12.9 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 KEZ37740.1 - 0.067 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KEZ37740.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.15 KEZ37740.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF3159 PF11361.8 KEZ37741.1 - 5.4e-58 195.8 15.7 6.8e-58 195.5 15.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3159) PorA PF11271.8 KEZ37741.1 - 6.8 5.9 6.4 0.45 9.8 1.0 1.7 2 0 0 2 2 2 0 Porin PorA tRNA_anti-codon PF01336.25 KEZ37742.1 - 3e-08 33.5 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FlgD_ig PF13860.6 KEZ37742.1 - 0.12 12.2 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 FlgD Ig-like domain DUF3710 PF12502.8 KEZ37743.1 - 2.4e-61 206.5 0.3 2.9e-61 206.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) dUTPase PF00692.19 KEZ37744.1 - 1.1e-31 109.2 0.0 1.3e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF4235 PF14019.6 KEZ37745.1 - 1.2e-21 76.6 9.2 1.8e-21 76.0 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) Hexapep PF00132.24 KEZ37746.1 - 2.6e-17 61.8 12.7 3.9e-07 29.5 4.3 4.4 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ37746.1 - 1.6e-07 31.0 10.5 0.0062 16.3 1.4 4.2 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 KEZ37747.1 - 5.4e-20 71.6 55.3 8.9e-20 70.9 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2569 PF10754.9 KEZ37747.1 - 0.0025 18.3 1.7 0.26 11.7 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2569) tRNA-synt_1 PF00133.22 KEZ37748.1 - 9.7e-84 281.7 0.0 3.1e-82 276.8 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEZ37748.1 - 1e-26 93.7 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KEZ37748.1 - 1.6e-15 56.8 0.0 2.1e-08 33.3 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KEZ37748.1 - 3.5e-06 26.2 0.0 0.00017 20.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 KEZ37748.1 - 7.8e-05 22.2 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Inositol_P PF00459.25 KEZ37749.1 - 7.2e-56 189.7 0.1 8.5e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Aconitase PF00330.20 KEZ37750.1 - 1.1e-176 588.4 0.0 1.5e-176 588.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ37750.1 - 2e-46 157.5 0.0 3.2e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_trans_1_4 PF13692.6 KEZ37751.1 - 6.4e-14 52.5 1.1 1.2e-13 51.6 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ37751.1 - 4.4e-09 36.6 4.2 4.4e-09 36.6 4.2 2.4 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEZ37751.1 - 5.4e-09 35.8 0.0 7.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ37752.1 - 1.3e-15 57.4 0.0 2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ37752.1 - 4.4e-13 49.8 0.3 9.4e-13 48.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ37752.1 - 1.6e-07 31.5 2.6 1.6e-07 31.5 2.6 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ37752.1 - 0.011 16.1 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 UDPG_MGDP_dh_N PF03721.14 KEZ37753.1 - 1.8e-40 138.6 0.0 1.9e-39 135.2 0.0 2.1 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KEZ37753.1 - 6.3e-27 93.6 0.0 1.3e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KEZ37753.1 - 4.2e-18 65.7 0.0 9.8e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KEZ37753.1 - 0.00015 22.0 0.0 0.00039 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KEZ37753.1 - 0.0025 18.3 2.8 0.1 13.1 0.0 2.6 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KEZ37753.1 - 0.0035 16.7 0.1 0.83 9.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEZ37753.1 - 0.013 15.7 0.3 0.056 13.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KEZ37753.1 - 0.031 14.2 0.2 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KEZ37753.1 - 0.047 12.9 0.0 0.21 10.8 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.6 KEZ37753.1 - 0.05 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AlaDh_PNT_C PF01262.21 KEZ37753.1 - 0.094 12.0 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KEZ37753.1 - 0.12 13.0 0.8 3.5 8.3 0.3 3.3 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEZ37753.1 - 0.19 12.2 0.6 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase_2 PF02350.19 KEZ37754.1 - 1e-101 340.3 0.0 1.2e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 KEZ37754.1 - 1.3e-05 25.7 3.3 1.3e-05 25.7 3.3 3.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Pyr_redox_2 PF07992.14 KEZ37754.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3368 PF11848.8 KEZ37754.1 - 0.13 12.0 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) GDP_Man_Dehyd PF16363.5 KEZ37755.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GntR PF00392.21 KEZ37757.1 - 5e-18 64.5 0.0 1.1e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family UTRA PF07702.13 KEZ37757.1 - 4.4e-16 59.0 0.2 6.8e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 UTRA domain HTH_Crp_2 PF13545.6 KEZ37757.1 - 0.00018 21.4 0.7 0.00052 19.9 0.5 1.9 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KEZ37757.1 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.12 KEZ37757.1 - 0.041 13.6 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KEZ37757.1 - 0.051 13.9 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_41 PF14502.6 KEZ37757.1 - 0.09 12.5 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain OrfB_Zn_ribbon PF07282.11 KEZ37758.1 - 1.6e-08 34.3 0.1 3e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain AAA_19 PF13245.6 KEZ37760.1 - 9.4e-15 55.2 0.0 4.9e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NERD PF08378.11 KEZ37760.1 - 2.3e-13 50.6 0.1 7e-13 49.0 0.0 1.9 2 0 0 2 2 1 1 Nuclease-related domain UvrD-helicase PF00580.21 KEZ37760.1 - 2.3e-12 47.1 0.0 3.1e-09 36.8 0.0 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEZ37760.1 - 2.4e-11 43.6 0.0 8.9e-07 28.6 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ37760.1 - 0.00035 20.4 2.6 0.47 10.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.6 KEZ37760.1 - 0.00046 20.0 0.5 0.0033 17.2 0.5 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KEZ37760.1 - 0.0064 15.8 0.0 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KEZ37760.1 - 0.019 15.0 0.3 0.044 13.8 0.3 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 KEZ37760.1 - 0.047 13.4 0.2 3.3 7.4 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KEZ37760.1 - 0.062 13.0 0.1 16 5.1 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KEZ37760.1 - 0.12 12.6 1.1 23 5.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 KEZ37760.1 - 0.18 11.8 0.1 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KEZ37760.1 - 3.5 8.0 11.1 0.067 13.6 0.6 3.4 3 2 0 3 3 3 0 AAA ATPase domain DoxX PF07681.12 KEZ37761.1 - 1.5e-14 54.3 14.9 1.5e-14 54.3 14.9 2.2 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 KEZ37761.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD DUF1918 PF08940.11 KEZ37762.1 - 1.5e-27 95.0 1.1 2.9e-27 94.0 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) CBS PF00571.28 KEZ37762.1 - 3.5e-23 81.8 7.5 7.2e-11 42.4 1.1 2.5 2 0 0 2 2 2 2 CBS domain NUDIX PF00293.28 KEZ37763.1 - 7.2e-12 45.5 0.3 1.3e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain His_Phos_1 PF00300.22 KEZ37763.1 - 2.8e-08 33.7 0.1 4.9e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fer4_22 PF17179.4 KEZ37764.1 - 2.1e-34 118.2 9.9 2.1e-34 118.2 9.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ37764.1 - 8.3e-09 35.9 2.1 0.0012 19.3 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KEZ37764.1 - 1.1e-07 31.5 12.4 0.0011 19.0 3.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ37764.1 - 1.5e-07 31.9 9.0 0.00071 20.1 0.8 2.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEZ37764.1 - 1.6e-07 31.3 9.6 0.003 17.7 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ37764.1 - 2.3e-07 30.9 5.0 0.009 16.2 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KEZ37764.1 - 5.7e-07 29.7 1.5 0.002 18.3 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ37764.1 - 7.9e-07 29.4 8.4 1e-05 25.9 8.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KEZ37764.1 - 7.2e-05 22.8 10.4 0.013 15.7 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KEZ37764.1 - 8.8e-05 22.2 15.4 0.018 14.8 3.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KEZ37764.1 - 0.00036 21.4 10.4 0.12 13.3 0.7 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KEZ37764.1 - 0.002 18.1 20.0 0.12 12.5 7.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KEZ37764.1 - 0.029 15.3 4.2 0.029 15.3 4.2 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 KEZ37764.1 - 0.034 13.9 6.5 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_4 PF12800.7 KEZ37764.1 - 0.4 11.3 22.4 1.4 9.7 3.5 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KEZ37764.1 - 0.53 10.9 13.6 2.2 8.9 5.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KEZ37764.1 - 2.8 8.7 11.4 4.4 8.1 2.1 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain cNMP_binding PF00027.29 KEZ37765.1 - 1.6e-11 44.1 0.0 2.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NAD_binding_1 PF00175.21 KEZ37766.1 - 1.7e-14 54.4 0.0 2.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 KEZ37766.1 - 0.00032 20.4 4.6 0.0006 19.6 4.6 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NAD_binding_6 PF08030.12 KEZ37766.1 - 0.1 12.7 0.0 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Oxidored_q6 PF01058.22 KEZ37767.1 - 1e-23 83.6 0.0 1.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit CHAD PF05235.14 KEZ37767.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 CHAD domain ATP-grasp_6 PF18419.1 KEZ37767.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp-like domain NiFeSe_Hases PF00374.19 KEZ37768.1 - 1.5e-28 100.0 0.2 2e-12 46.8 0.0 3.1 2 1 1 3 3 3 3 Nickel-dependent hydrogenase HycI PF01750.18 KEZ37769.1 - 1.6e-08 34.5 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease CBS PF00571.28 KEZ37770.1 - 1.3e-16 60.7 0.5 6e-07 29.8 0.2 2.4 2 0 0 2 2 2 2 CBS domain Peptidase_M50 PF02163.22 KEZ37770.1 - 4.9e-14 52.2 6.3 1.3e-08 34.5 0.2 2.6 1 1 1 2 2 2 2 Peptidase family M50 DUF3267 PF11667.8 KEZ37770.1 - 0.016 15.5 0.4 0.016 15.5 0.4 2.4 3 0 0 3 3 3 0 Putative zincin peptidase DHFR_2 PF06442.11 KEZ37770.1 - 0.1 12.5 0.2 0.31 10.9 0.2 1.8 1 0 0 1 1 1 0 R67 dihydrofolate reductase TOBE PF03459.17 KEZ37771.1 - 6e-36 122.5 11.6 3.4e-18 65.7 2.3 2.0 2 0 0 2 2 2 2 TOBE domain TOBE_2 PF08402.10 KEZ37771.1 - 1.1e-08 35.1 5.5 0.00011 22.2 0.4 2.1 1 1 1 2 2 2 2 TOBE domain TOBE_3 PF12857.7 KEZ37771.1 - 0.0015 18.4 0.0 1.9 8.5 0.1 2.2 2 0 0 2 2 2 2 TOBE-like domain OB_aCoA_assoc PF01796.17 KEZ37771.1 - 0.092 12.8 1.0 2.5 8.2 0.1 2.4 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated HMGL-like PF00682.19 KEZ37774.1 - 2.3e-77 260.1 0.0 2.8e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Fer4_NifH PF00142.18 KEZ37775.1 - 2.9e-135 450.0 1.8 3.3e-135 449.8 1.8 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KEZ37775.1 - 9.5e-10 38.7 1.7 2e-09 37.6 0.2 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KEZ37775.1 - 1.9e-09 37.6 0.0 3.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KEZ37775.1 - 1.4e-07 31.0 0.2 3.8e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase ParA PF10609.9 KEZ37775.1 - 3.3e-06 26.7 1.1 0.00012 21.7 0.1 2.3 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MeaB PF03308.16 KEZ37775.1 - 0.0018 17.3 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MipZ PF09140.11 KEZ37775.1 - 0.0078 15.5 0.4 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ AAA_10 PF12846.7 KEZ37775.1 - 0.021 13.8 0.3 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.22 KEZ37775.1 - 0.043 13.5 0.6 0.081 12.5 0.2 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KEZ37775.1 - 0.14 11.9 0.2 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Oxidored_nitro PF00148.19 KEZ37776.1 - 1e-108 363.6 0.0 1.2e-108 363.4 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Oxidored_nitro PF00148.19 KEZ37777.1 - 4.3e-123 411.0 0.0 5e-123 410.8 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF3364 PF11844.8 KEZ37777.1 - 7.8e-24 83.7 0.4 1.4e-23 82.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3364) Oxidored_nitro PF00148.19 KEZ37778.1 - 5.5e-102 341.5 0.0 6.3e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Oxidored_nitro PF00148.19 KEZ37779.1 - 2.3e-127 425.1 0.0 2.7e-127 424.8 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase HAMP PF00672.25 KEZ37779.1 - 0.0026 18.1 1.3 0.017 15.5 1.3 2.5 1 0 0 1 1 1 1 HAMP domain Nitro_FeMo-Co PF02579.17 KEZ37780.1 - 1.9e-18 66.6 0.0 2.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor DUF269 PF03270.13 KEZ37781.1 - 9e-46 154.9 0.0 1.1e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF269 Viral_P18 PF04521.13 KEZ37781.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.3 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Rop-like PF05082.13 KEZ37782.1 - 4.4e-13 48.8 0.3 6.3e-13 48.3 0.3 1.2 1 0 0 1 1 1 1 Rop-like NifW PF03206.14 KEZ37783.1 - 1.4e-27 96.0 0.1 1.8e-27 95.8 0.1 1.1 1 0 0 1 1 1 1 Nitrogen fixation protein NifW NifZ PF04319.13 KEZ37784.1 - 1.1e-23 82.8 0.4 1.4e-23 82.4 0.4 1.2 1 0 0 1 1 1 1 NifZ domain Radical_SAM PF04055.21 KEZ37785.1 - 2.9e-30 105.8 0.1 6e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Nitro_FeMo-Co PF02579.17 KEZ37785.1 - 5.7e-19 68.2 0.0 1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Fer4_14 PF13394.6 KEZ37785.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KEZ37785.1 - 0.0049 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain NifU PF01106.17 KEZ37786.1 - 2.6e-21 75.5 0.1 5.1e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain Fe-S_biosyn PF01521.20 KEZ37786.1 - 2.4e-20 72.8 0.0 4.5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ThiF PF00899.21 KEZ37787.1 - 2e-46 158.3 0.0 2.4e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KEZ37787.1 - 0.0014 18.9 4.1 0.021 15.1 4.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KEZ37787.1 - 0.037 14.5 0.0 0.057 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KEZ37787.1 - 0.14 11.5 1.8 0.25 10.7 1.0 1.8 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 KEZ37788.1 - 6.4e-66 222.8 0.0 1.2e-65 221.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V POR_N PF01855.19 KEZ37789.1 - 1.2e-50 172.5 0.1 1.8e-50 171.8 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KEZ37789.1 - 2.7e-30 105.7 0.3 4.3e-30 105.1 0.3 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KEZ37789.1 - 1.2e-06 28.7 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_N PF02776.18 KEZ37789.1 - 0.00085 19.0 0.8 0.0021 17.7 0.8 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transketolase_C PF02780.20 KEZ37789.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KEZ37790.1 - 3.8e-31 107.9 0.0 6e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.27 KEZ37791.1 - 8.3e-13 47.6 15.2 4.2e-10 39.0 5.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KEZ37791.1 - 2.5e-08 33.9 4.6 2.8e-06 27.3 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ37791.1 - 2.5e-07 31.5 6.8 8.3e-06 26.6 0.7 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KEZ37791.1 - 1.3e-06 28.9 11.5 6.1e-06 26.7 11.6 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ37791.1 - 5.2e-06 26.3 16.3 5.3e-06 26.3 5.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ37791.1 - 6.8e-06 25.9 3.3 6.8e-06 25.9 3.3 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KEZ37791.1 - 1.8e-05 24.8 10.0 2.8e-05 24.2 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KEZ37791.1 - 0.00014 22.0 3.2 0.00014 22.0 3.2 1.9 1 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEZ37791.1 - 0.00029 21.1 2.5 0.00029 21.1 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 KEZ37791.1 - 0.0053 17.2 2.2 0.0053 17.2 2.2 2.1 1 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 KEZ37791.1 - 0.016 15.7 4.9 0.016 15.7 4.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KEZ37791.1 - 0.016 16.1 16.8 0.02 15.8 5.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KEZ37791.1 - 0.15 12.6 10.5 0.17 12.4 2.9 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KEZ37791.1 - 1 10.1 12.5 13 6.6 5.8 3.1 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 KEZ37791.1 - 9.7 6.4 13.9 0.15 12.3 3.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain CMD PF02627.20 KEZ37792.1 - 1e-18 67.2 1.0 1.6e-18 66.5 1.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Response_reg PF00072.24 KEZ37793.1 - 2.4e-15 56.6 0.1 2.9e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain LSDAT_euk PF18139.1 KEZ37793.1 - 0.058 12.8 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 SLOG in TRPM CSD PF00313.22 KEZ37794.1 - 1.5e-30 104.9 0.6 1.6e-30 104.8 0.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KEZ37794.1 - 0.00026 20.6 0.2 0.00036 20.2 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain PCMT PF01135.19 KEZ37795.1 - 4.8e-36 124.5 0.0 6.8e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KEZ37795.1 - 1.9e-06 28.4 0.0 4.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KEZ37795.1 - 3.5e-06 26.3 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 KEZ37795.1 - 3.8e-06 26.8 0.0 6.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEZ37795.1 - 4.9e-05 22.6 0.1 9.6e-05 21.6 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.6 KEZ37795.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ37795.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KEZ37795.1 - 0.0039 17.8 0.0 0.0077 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KEZ37795.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F GCD14 PF08704.10 KEZ37795.1 - 0.011 15.5 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Fibrillarin PF01269.17 KEZ37795.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_24 PF13578.6 KEZ37795.1 - 0.032 15.2 1.2 0.098 13.7 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain ACP_syn_III_C PF08541.10 KEZ37795.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CMAS PF02353.20 KEZ37795.1 - 0.25 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Lant_dehydr_C PF14028.6 KEZ37796.1 - 4.8e-31 108.5 9.9 1.8e-30 106.6 9.9 1.7 1 1 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term OsmC PF02566.19 KEZ37797.1 - 1.2e-14 54.6 0.0 2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein p450 PF00067.22 KEZ37798.1 - 2.4e-78 263.9 0.0 3.1e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HATPase_c PF02518.26 KEZ37801.1 - 0.0097 16.4 0.0 0.01 16.3 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Esterase_phd PF10503.9 KEZ37802.1 - 1.7e-12 47.4 2.8 3.6e-12 46.2 2.1 1.8 1 1 1 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ37802.1 - 0.0022 17.5 0.4 0.015 14.8 0.2 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family BacA PF02673.18 KEZ37803.1 - 1.6e-81 273.8 4.5 1.9e-81 273.6 4.5 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA DUF1538 PF07556.11 KEZ37803.1 - 0.013 14.8 6.4 0.023 14.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) A_deaminase PF00962.22 KEZ37804.1 - 1.2e-60 205.6 0.0 2e-59 201.6 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Gly_kinase PF02595.15 KEZ37805.1 - 3.3e-108 361.9 8.5 3.8e-108 361.8 8.5 1.0 1 0 0 1 1 1 1 Glycerate kinase family Amidase_2 PF01510.25 KEZ37806.1 - 5.1e-11 43.1 0.0 1.1e-10 42.1 0.0 1.5 2 0 0 2 2 2 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 KEZ37806.1 - 1.9e-07 31.2 0.0 6.6e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Putative peptidoglycan binding domain AdoHcyase PF05221.17 KEZ37808.1 - 1.5e-152 506.9 0.0 1.7e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KEZ37808.1 - 1.8e-84 281.7 2.7 2.6e-84 281.2 2.7 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ37808.1 - 1.3e-09 37.7 0.1 2.3e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KEZ37808.1 - 6.5e-06 25.8 0.2 1.2e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KEZ37808.1 - 0.00039 20.7 1.0 0.0018 18.5 1.0 2.1 1 1 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 KEZ37808.1 - 0.019 14.3 1.9 0.073 12.4 1.9 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KEZ37808.1 - 0.026 14.6 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KEZ37808.1 - 0.15 12.5 0.4 0.46 10.9 0.3 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding MMPL PF03176.15 KEZ37809.1 - 3.2e-44 151.2 28.7 3.2e-25 88.8 6.4 3.1 3 0 0 3 3 3 2 MMPL family Sterol-sensing PF12349.8 KEZ37809.1 - 2.4e-12 46.9 0.8 2.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 KEZ37809.1 - 0.00016 21.2 20.2 0.00017 21.0 2.1 2.7 3 0 0 3 3 3 2 Protein export membrane protein Patched PF02460.18 KEZ37809.1 - 0.0031 15.7 9.9 0.13 10.3 4.9 2.1 2 0 0 2 2 2 2 Patched family Thiolase_N PF00108.23 KEZ37810.1 - 1.2e-63 214.9 0.2 1.8e-62 211.1 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ37810.1 - 3.3e-45 152.7 0.4 5.7e-45 151.9 0.4 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF1918 PF08940.11 KEZ37810.1 - 3e-25 87.6 1.6 6.3e-25 86.6 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) ketoacyl-synt PF00109.26 KEZ37810.1 - 8.8e-06 25.5 2.4 6.4e-05 22.7 1.3 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KEZ37810.1 - 0.0045 16.8 1.3 0.29 11.0 0.2 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_C2 PF00648.21 KEZ37811.1 - 6.1e-20 71.4 0.0 7.3e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease DUF692 PF05114.13 KEZ37811.1 - 0.18 10.9 0.0 0.52 9.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF692) Usp PF00582.26 KEZ37812.1 - 4.6e-41 140.6 6.2 4.9e-24 85.4 0.3 2.4 2 1 0 2 2 2 2 Universal stress protein family PaaX PF07848.12 KEZ37813.1 - 0.00014 22.0 0.2 0.00097 19.3 0.1 2.5 1 1 1 2 2 2 1 PaaX-like protein MarR_2 PF12802.7 KEZ37813.1 - 0.0032 17.3 0.2 0.012 15.5 0.2 2.0 1 0 0 1 1 1 1 MarR family HTH_29 PF13551.6 KEZ37813.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_36 PF13730.6 KEZ37813.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GMC_oxred_N PF00732.19 KEZ37814.1 - 5.2e-15 55.6 0.0 7.7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ37814.1 - 3.6e-14 53.5 0.0 7.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KEZ37814.1 - 1.5e-09 37.9 0.5 5.4e-09 36.1 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ37814.1 - 5.1e-08 32.5 0.0 5.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ37814.1 - 4.9e-07 29.2 0.4 1.2e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ37814.1 - 1.5e-05 25.1 0.1 3.9e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ37814.1 - 0.0028 16.8 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KEZ37814.1 - 0.0043 16.4 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ37814.1 - 0.0049 15.6 0.1 0.01 14.6 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ37814.1 - 0.0069 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ37814.1 - 0.0086 16.6 0.0 0.22 12.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 KEZ37814.1 - 0.025 14.7 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain UDPG_MGDP_dh_N PF03721.14 KEZ37814.1 - 0.15 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CCDC-167 PF15188.6 KEZ37815.1 - 0.33 11.3 5.0 0.61 10.5 5.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 eIF3_subunit PF08597.10 KEZ37815.1 - 1.7 8.5 10.6 3 7.7 10.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pro_isomerase PF00160.21 KEZ37816.1 - 9.8e-48 162.4 0.0 1.1e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rhomboid PF01694.22 KEZ37817.1 - 4e-30 104.8 12.1 4e-30 104.8 12.1 1.7 2 0 0 2 2 2 1 Rhomboid family zf-B_box PF00643.24 KEZ37817.1 - 0.003 17.7 4.8 0.0046 17.1 4.8 1.2 1 0 0 1 1 1 1 B-box zinc finger zf-UDP PF14569.6 KEZ37817.1 - 0.056 13.6 1.8 0.092 12.9 1.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Tnp_zf-ribbon_2 PF13842.6 KEZ37817.1 - 0.17 12.7 5.2 0.41 11.5 5.2 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF1751 PF08551.10 KEZ37817.1 - 0.91 10.1 3.4 0.69 10.5 0.7 2.3 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Glyco_hydro_15 PF00723.21 KEZ37818.1 - 1.3e-53 182.4 0.0 4.3e-49 167.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Ribonuc_L-PSP PF01042.21 KEZ37820.1 - 5.9e-21 74.7 0.0 6.9e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TetR_C_16 PF17920.1 KEZ37820.1 - 0.029 14.6 0.6 0.039 14.2 0.6 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Serglycin PF04360.12 KEZ37820.1 - 0.041 13.8 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 Serglycin CrgA PF06781.12 KEZ37821.1 - 3.6e-26 91.1 0.0 3.9e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Cell division protein CrgA FixP_N PF14715.6 KEZ37821.1 - 0.023 14.5 1.1 0.044 13.5 1.1 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP PMP1_2 PF08114.11 KEZ37821.1 - 3.4 7.5 7.8 2.9 7.7 0.7 2.3 2 0 0 2 2 2 0 ATPase proteolipid family DUF881 PF05949.12 KEZ37822.1 - 2.5e-36 124.7 0.0 3.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) GATase PF00117.28 KEZ37823.1 - 7.1e-50 169.4 0.0 8e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ37823.1 - 5.1e-12 46.0 0.1 1.8e-11 44.2 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiG_mid PF11761.8 KEZ37823.1 - 0.099 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Pkinase PF00069.25 KEZ37824.1 - 4.9e-51 173.6 0.0 6.9e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PASTA PF03793.19 KEZ37824.1 - 1.2e-35 121.1 9.6 1e-13 50.9 0.1 3.7 3 0 0 3 3 3 3 PASTA domain Pkinase_Tyr PF07714.17 KEZ37824.1 - 9.4e-33 113.6 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ37824.1 - 2.2e-06 27.8 0.1 0.0018 18.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ37824.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ37824.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KEZ37824.1 - 0.035 13.7 0.1 0.072 12.7 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 KEZ37824.1 - 0.041 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF2970 PF11174.8 KEZ37824.1 - 0.1 12.5 0.5 0.21 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Pkinase PF00069.25 KEZ37825.1 - 1.4e-42 145.9 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ37825.1 - 2.9e-31 108.7 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ37825.1 - 3.4e-06 27.2 4.0 0.0013 18.7 1.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ37825.1 - 0.0037 16.7 0.0 0.0052 16.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ37825.1 - 0.039 13.3 0.0 0.084 12.2 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Transpeptidase PF00905.22 KEZ37826.1 - 5.3e-74 249.2 0.0 7.1e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Beta-lactamase2 PF13354.6 KEZ37826.1 - 0.0008 19.1 0.1 0.013 15.2 0.1 2.6 1 1 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 KEZ37826.1 - 0.009 14.8 1.6 0.011 14.5 0.3 1.8 2 0 0 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family FTSW_RODA_SPOVE PF01098.19 KEZ37827.1 - 1.1e-82 277.9 21.9 1.1e-82 277.9 21.9 1.3 2 0 0 2 2 2 1 Cell cycle protein PP2C_2 PF13672.6 KEZ37828.1 - 2.2e-13 50.4 1.1 3.9e-13 49.5 1.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KEZ37828.1 - 3.1e-11 43.4 0.1 1.3e-09 38.1 0.1 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C BofC_C PF08955.10 KEZ37828.1 - 0.0032 17.5 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 BofC C-terminal domain Yop-YscD_cpl PF16697.5 KEZ37829.1 - 2.8e-16 59.6 0.0 3.6e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KEZ37829.1 - 6.8e-16 58.4 0.0 9.6e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 FHA domain DUF3662 PF12401.8 KEZ37830.1 - 1.8e-39 134.7 0.1 2.4e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2662) Yop-YscD_cpl PF16697.5 KEZ37830.1 - 2.8e-15 56.4 0.0 4.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KEZ37830.1 - 1.1e-14 54.5 0.2 1.9e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 FHA domain PurS PF02700.14 KEZ37831.1 - 1.8e-22 79.3 0.0 2.1e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase HAD PF12710.7 KEZ37832.1 - 2.8e-08 34.4 4.1 1.1e-07 32.4 3.5 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ37832.1 - 3.4e-07 30.5 0.0 3.3e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ37832.1 - 0.00021 21.3 1.4 0.00034 20.6 1.4 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like SBP_bac_3 PF00497.20 KEZ37832.1 - 0.021 14.3 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF697 PF05128.12 KEZ37833.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF697) CSD PF00313.22 KEZ37834.1 - 1.1e-18 66.8 0.0 1.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KEZ37834.1 - 0.0021 17.7 0.6 0.0048 16.6 0.6 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain TipAS PF07739.13 KEZ37834.1 - 0.013 16.0 0.0 0.017 15.7 0.0 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain CusF_Ec PF11604.8 KEZ37834.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Nudix_N_2 PF14803.6 KEZ37835.1 - 0.03 14.3 2.7 0.15 12.0 2.7 1.9 1 1 0 1 1 1 0 Nudix N-terminal zf-ribbon_3 PF13248.6 KEZ37835.1 - 0.039 13.4 2.1 0.44 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KEZ37835.1 - 0.039 14.0 0.3 0.064 13.3 0.3 1.3 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 KEZ37835.1 - 0.049 14.0 0.2 0.063 13.7 0.2 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar PknG_rubred PF16919.5 KEZ37835.1 - 0.12 12.5 0.6 0.14 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DUF3268 PF11672.8 KEZ37835.1 - 0.2 12.0 0.0 0.25 11.7 0.0 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KEZ37835.1 - 0.26 11.4 2.2 11 6.2 0.1 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf_C2H2_13 PF18508.1 KEZ37835.1 - 0.32 10.6 1.0 15 5.3 0.1 2.1 2 0 0 2 2 2 0 Zinc finger domain Pkinase PF00069.25 KEZ37837.1 - 7.6e-37 127.1 0.0 1e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4352 PF11611.8 KEZ37837.1 - 3e-26 92.1 0.0 4.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) Pkinase_Tyr PF07714.17 KEZ37837.1 - 7.2e-21 74.6 0.0 9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ37837.1 - 1.9e-05 24.7 3.3 0.0031 17.5 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4307 PF14155.6 KEZ37837.1 - 0.0044 16.8 0.3 2 8.3 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4307) RIO1 PF01163.22 KEZ37837.1 - 0.0055 16.3 0.0 0.046 13.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family ABC1 PF03109.16 KEZ37837.1 - 0.009 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Kdo PF06293.14 KEZ37837.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1524 PF07510.11 KEZ37838.1 - 2.7e-15 56.5 0.0 3.3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KEZ37838.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.7 1 1 0 1 1 1 0 HNH endonuclease GH-E PF14410.6 KEZ37838.1 - 0.082 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Rhodanese PF00581.20 KEZ37839.1 - 2.1e-16 60.4 0.0 2.3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain VitK2_biosynth PF02621.14 KEZ37840.1 - 3.6e-83 279.2 0.0 4e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis PNP_UDP_1 PF01048.20 KEZ37841.1 - 4.6e-18 65.3 0.7 6.7e-18 64.8 0.7 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily HAS-barrel PF09378.10 KEZ37841.1 - 0.076 13.2 0.1 0.57 10.4 0.1 2.1 1 1 0 1 1 1 0 HAS barrel domain DUF2771 PF10969.8 KEZ37843.1 - 0.0077 16.3 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2771) MFS_1 PF07690.16 KEZ37844.1 - 7.2e-14 51.5 56.7 1.3e-10 40.8 38.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KEZ37844.1 - 1.6 6.9 9.6 3.1 6.0 9.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3027 PF11228.8 KEZ37845.1 - 9.8e-78 260.6 0.0 1.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) AIRS_C PF02769.22 KEZ37846.1 - 6.5e-47 159.6 5.5 2e-27 96.2 0.9 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KEZ37846.1 - 3.1e-43 146.3 6.0 1.8e-21 76.6 0.9 2.4 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 KEZ37846.1 - 7.2e-16 58.5 0.0 1.5e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_5 PF13507.6 KEZ37847.1 - 3.4e-35 121.4 0.0 5e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 KEZ37847.1 - 6.3e-09 35.7 0.0 1.3e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KEZ37847.1 - 7e-07 29.2 0.0 1.2e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KEZ37847.1 - 1.3e-05 25.1 0.0 2.2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KEZ37847.1 - 0.00052 19.8 0.7 0.0026 17.5 0.8 1.8 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 KEZ37847.1 - 0.0062 16.4 0.0 0.0083 16.0 0.0 1.5 1 1 0 1 1 1 1 SNO glutamine amidotransferase family HATPase_c_2 PF13581.6 KEZ37848.1 - 4.8e-22 78.2 0.1 6.1e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ37848.1 - 0.00011 22.7 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_8 PF13450.6 KEZ37849.1 - 1.3e-13 50.9 0.5 1.1e-12 48.0 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEZ37849.1 - 1.1e-10 41.5 3.3 1.7e-06 27.6 0.2 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KEZ37849.1 - 3.5e-06 26.6 0.1 4.5e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ37849.1 - 0.0025 18.3 0.0 0.072 13.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ37849.1 - 0.0054 16.4 10.8 0.091 12.3 9.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ37849.1 - 0.02 14.0 1.5 0.026 13.6 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KEZ37849.1 - 0.028 13.7 0.8 0.091 12.0 0.8 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ37849.1 - 0.29 10.4 1.9 0.44 9.8 1.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEZ37849.1 - 0.94 8.1 3.0 1.4 7.6 3.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEZ37851.1 - 4.5e-11 42.6 8.1 6e-10 38.9 4.1 2.4 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEZ37851.1 - 1.5e-06 28.1 6.1 0.0025 17.5 2.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ37851.1 - 1.1e-05 24.9 0.3 1.1e-05 24.9 0.3 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KEZ37851.1 - 1.3e-05 24.4 4.6 3.2e-05 23.2 4.6 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ37851.1 - 3.2e-05 22.8 1.1 5e-05 22.2 1.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ37851.1 - 3.4e-05 23.2 2.9 6e-05 22.4 1.6 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ37851.1 - 0.00057 19.1 3.0 0.00057 19.1 3.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ37851.1 - 0.00065 19.2 11.0 0.0013 18.2 10.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ37851.1 - 0.0024 18.1 0.5 0.0024 18.1 0.5 3.2 3 1 1 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ37851.1 - 0.004 16.5 0.3 0.006 15.9 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ37851.1 - 0.014 16.0 0.2 0.099 13.2 0.6 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ37851.1 - 0.14 11.2 11.6 0.026 13.6 5.7 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KEZ37851.1 - 0.22 10.3 0.8 0.36 9.6 0.8 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KEZ37851.1 - 0.23 10.7 6.6 0.058 12.7 2.5 1.9 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEZ37851.1 - 0.24 11.3 0.2 0.39 10.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CbiA PF01656.23 KEZ37852.1 - 1.1e-08 35.2 0.0 3.9e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEZ37852.1 - 3.2e-08 33.7 0.1 5.7e-08 32.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 KEZ37852.1 - 0.0002 20.9 0.1 0.00036 20.1 0.1 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KEZ37852.1 - 0.00041 19.9 0.2 0.0021 17.6 0.2 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KEZ37852.1 - 0.005 16.1 0.1 0.007 15.6 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 KEZ37852.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein APH PF01636.23 KEZ37853.1 - 1.8e-13 51.0 8.4 2.5e-13 50.5 8.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2252 PF10009.9 KEZ37853.1 - 1.8e-06 27.3 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) TPR_4 PF07721.14 KEZ37854.1 - 0.00031 21.1 29.2 0.99 10.2 0.6 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ37854.1 - 0.016 15.8 18.8 0.25 12.0 10.4 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ37854.1 - 0.036 14.4 11.5 0.62 10.4 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ37854.1 - 0.036 14.2 10.4 3.4 8.0 1.7 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF218 PF02698.17 KEZ37854.1 - 0.11 12.5 0.9 0.41 10.7 0.3 2.1 2 0 0 2 2 2 0 DUF218 domain TPR_14 PF13428.6 KEZ37854.1 - 2.1 9.4 25.7 6.7 7.8 4.3 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KEZ37855.1 - 2.1e-08 34.4 0.1 3.4e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEZ37855.1 - 4.2e-06 26.6 0.0 9.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KEZ37855.1 - 0.00012 22.4 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ37855.1 - 0.0029 17.5 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pterin_bind PF00809.22 KEZ37856.1 - 7.3e-77 258.3 1.3 8.6e-77 258.1 1.3 1.1 1 0 0 1 1 1 1 Pterin binding enzyme Aldolase PF01081.19 KEZ37856.1 - 0.18 11.2 1.5 1.6 8.1 0.6 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase FolB PF02152.18 KEZ37857.1 - 2.7e-31 108.4 0.0 3.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroneopterin aldolase HPPK PF01288.20 KEZ37858.1 - 3.4e-31 108.1 0.0 4.2e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3180 PF11377.8 KEZ37859.1 - 1.8e-38 131.7 14.1 2e-38 131.6 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) Helicase_C_3 PF13625.6 KEZ37863.1 - 8.1e-39 132.7 0.3 1.8e-38 131.6 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WYL PF13280.6 KEZ37863.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 1 WYL domain ERCC3_RAD25_C PF16203.5 KEZ37864.1 - 5.6e-47 160.0 0.0 7.9e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KEZ37864.1 - 3.9e-44 149.9 1.0 8.6e-44 148.8 1.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ37864.1 - 6.9e-12 45.7 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEZ37864.1 - 4.7e-10 39.8 0.0 8.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEZ37864.1 - 0.00044 19.1 0.0 0.0013 17.6 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.6 KEZ37864.1 - 0.049 13.9 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KEZ37864.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Uma2 PF05685.12 KEZ37865.1 - 9.8e-25 87.1 0.0 1.2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Cpn60_TCP1 PF00118.24 KEZ37866.1 - 1.5e-93 314.1 12.7 2.1e-93 313.6 12.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PALP PF00291.25 KEZ37867.1 - 3.4e-64 217.1 3.5 4e-64 216.8 3.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MerR PF00376.23 KEZ37867.1 - 0.0075 16.0 0.0 0.027 14.2 0.0 2.0 1 0 0 1 1 1 1 MerR family regulatory protein MmgE_PrpD PF03972.14 KEZ37867.1 - 0.031 12.8 0.3 0.045 12.3 0.0 1.4 2 0 0 2 2 2 0 MmgE/PrpD family HypA PF01155.19 KEZ37867.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NinF PF05810.12 KEZ37867.1 - 0.14 12.0 0.7 0.31 10.9 0.7 1.5 1 0 0 1 1 1 0 NinF protein Hydrolase_3 PF08282.12 KEZ37868.1 - 4.5e-13 49.5 0.0 4e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ37868.1 - 8.7e-07 29.5 2.3 0.03 14.7 0.1 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEZ37868.1 - 2.9e-05 23.7 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KEZ37868.1 - 0.00059 20.2 1.6 0.35 11.1 0.0 2.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ37868.1 - 0.006 16.7 0.2 0.53 10.3 0.0 2.4 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Glyco_transf_20 PF00982.21 KEZ37869.1 - 3.1e-95 319.6 0.0 4e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KEZ37871.1 - 1.5e-28 99.6 0.0 1.8e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KEZ37871.1 - 0.00019 21.3 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEZ37871.1 - 0.074 12.6 0.0 8.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase LytR_C PF13399.6 KEZ37872.1 - 8e-13 49.2 2.5 8.1e-13 49.2 0.3 1.9 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator FAP PF07174.11 KEZ37872.1 - 0.034 13.6 17.3 0.046 13.2 17.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Totivirus_coat PF05518.11 KEZ37872.1 - 0.28 9.2 10.6 0.48 8.4 10.6 1.4 1 0 0 1 1 1 0 Totivirus coat protein DUF3263 PF11662.8 KEZ37873.1 - 2.1e-35 120.4 5.3 2.7e-35 120.0 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3263) RNHCP PF12647.7 KEZ37874.1 - 3.5e-27 94.2 5.0 4.4e-27 93.9 5.0 1.1 1 0 0 1 1 1 1 RNHCP domain DZR PF12773.7 KEZ37874.1 - 0.024 14.7 5.1 0.87 9.7 1.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon RNF220 PF15926.5 KEZ37874.1 - 0.086 12.4 0.5 0.15 11.7 0.3 1.5 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase RNF220 TF_Zn_Ribbon PF08271.12 KEZ37874.1 - 0.11 12.0 7.7 7.9 6.1 0.3 3.5 2 1 1 3 3 3 0 TFIIB zinc-binding HypA PF01155.19 KEZ37874.1 - 0.31 11.1 4.1 0.51 10.4 0.4 2.1 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 KEZ37874.1 - 0.99 9.4 8.8 1.6 8.7 0.3 3.3 3 0 0 3 3 3 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 KEZ37874.1 - 3.3 7.7 7.9 15 5.6 0.9 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain ELFV_dehydrog PF00208.21 KEZ37875.1 - 1.5e-63 214.8 0.0 1.8e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KEZ37875.1 - 1.5e-55 186.6 0.0 1.6e-54 183.3 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KEZ37875.1 - 0.005 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KEZ37875.1 - 0.13 11.9 0.4 0.25 11.0 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Leader_Trp PF08255.11 KEZ37876.1 - 0.022 14.7 0.9 0.022 14.7 0.9 3.5 3 0 0 3 3 3 0 Trp-operon Leader Peptide MaAIMP_sms PF16951.5 KEZ37877.1 - 3.1 7.6 5.6 1.1 9.0 0.5 2.9 3 0 0 3 3 3 0 Putative methionine and alanine importer, small subunit PP2C_2 PF13672.6 KEZ37879.1 - 1e-11 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEZ37879.1 - 4.6e-11 43.0 0.2 6.4e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KEZ37879.1 - 3e-09 36.9 0.0 0.00014 21.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Pur_ac_phosph_N PF16656.5 KEZ37881.1 - 1.5e-17 64.0 0.0 2.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KEZ37881.1 - 2.3e-10 41.3 0.2 9.9e-10 39.3 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_2 PF07724.14 KEZ37882.1 - 5.1e-58 196.0 0.0 4.8e-56 189.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 KEZ37882.1 - 1.8e-36 124.1 7.9 3.2e-18 65.6 0.9 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 KEZ37882.1 - 8.4e-34 115.6 1.1 8.4e-34 115.6 1.1 2.0 2 0 0 2 2 1 1 AAA lid domain ClpB_D2-small PF10431.9 KEZ37882.1 - 2.9e-26 91.3 0.7 1.5e-25 89.0 0.7 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KEZ37882.1 - 2.2e-22 79.9 0.0 2.2e-12 47.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEZ37882.1 - 6.1e-20 71.6 0.0 3.6e-13 49.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ37882.1 - 7.4e-13 49.2 5.4 1.2e-06 29.0 0.0 4.4 4 1 1 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 KEZ37882.1 - 4.7e-10 39.9 0.6 0.0017 18.6 0.1 4.1 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 KEZ37882.1 - 9.8e-09 34.9 2.2 3.8e-06 26.4 0.1 4.0 3 2 1 4 4 3 1 Bacterial TniB protein UVR PF02151.19 KEZ37882.1 - 3.9e-07 29.6 3.4 1.3e-06 28.0 3.4 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif Sigma54_activat PF00158.26 KEZ37882.1 - 5.1e-07 29.6 0.2 0.0007 19.3 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 KEZ37882.1 - 8.6e-07 29.1 1.0 0.038 13.9 0.1 3.8 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KEZ37882.1 - 4.2e-05 23.3 0.0 0.067 12.9 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KEZ37882.1 - 8e-05 22.6 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KEZ37882.1 - 8.2e-05 23.2 2.0 0.12 13.0 0.0 3.4 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.22 KEZ37882.1 - 0.00018 21.8 0.0 0.83 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KEZ37882.1 - 0.00029 20.6 0.4 3.1 7.5 0.0 4.2 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEZ37882.1 - 0.00031 20.9 1.4 1.2 9.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain TsaE PF02367.17 KEZ37882.1 - 0.0004 20.4 0.4 0.45 10.5 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KEZ37882.1 - 0.00046 20.2 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KEZ37882.1 - 0.00049 19.5 0.3 3.6 6.9 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KEZ37882.1 - 0.00057 19.4 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KEZ37882.1 - 0.00069 19.4 0.0 0.28 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KEZ37882.1 - 0.0014 18.5 0.1 1.2 9.0 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEZ37882.1 - 0.0016 18.4 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.15 KEZ37882.1 - 0.0031 17.5 0.0 1.3 9.0 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KEZ37882.1 - 0.0055 16.3 0.1 2 7.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KEZ37882.1 - 0.0086 16.3 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KEZ37882.1 - 0.0088 15.8 0.0 2.4 7.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEZ37882.1 - 0.011 15.9 0.0 9.6 6.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KEZ37882.1 - 0.014 15.2 0.0 0.49 10.2 0.0 2.8 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Torsin PF06309.11 KEZ37882.1 - 0.021 14.9 0.0 0.46 10.6 0.0 2.7 3 0 0 3 3 3 0 Torsin ABC_tran PF00005.27 KEZ37882.1 - 0.022 15.3 0.0 3.9 8.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 KEZ37882.1 - 0.027 14.8 1.3 0.49 10.7 0.1 3.2 2 2 1 3 3 3 0 AAA domain DUF815 PF05673.13 KEZ37882.1 - 0.032 13.4 0.1 1.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KEZ37882.1 - 0.045 13.7 0.2 11 5.8 0.0 3.0 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.12 KEZ37882.1 - 0.054 12.8 0.0 6 6.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 KEZ37882.1 - 0.073 12.8 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain FhuF_C PF11575.8 KEZ37883.1 - 1.8e-06 27.7 7.3 3.4e-06 26.8 7.3 1.5 1 0 0 1 1 1 1 FhuF 2Fe-2S C-terminal domain FhuF PF06276.12 KEZ37883.1 - 0.0021 18.5 0.2 0.0037 17.7 0.2 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Lipase_GDSL_2 PF13472.6 KEZ37884.1 - 4.5e-25 89.1 0.1 1.1e-24 87.8 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ37884.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pan_kinase PF03309.14 KEZ37885.1 - 9.7e-64 215.0 0.2 1.2e-63 214.7 0.2 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase QRPTase_C PF01729.19 KEZ37886.1 - 7e-54 182.1 0.1 9.2e-54 181.7 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KEZ37886.1 - 4.1e-25 87.7 0.1 1.7e-24 85.7 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain FAD_binding_2 PF00890.24 KEZ37887.1 - 6.5e-86 289.0 17.4 9.2e-86 288.5 17.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KEZ37887.1 - 1e-15 57.9 0.1 3.2e-15 56.2 0.1 1.8 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 KEZ37887.1 - 6.1e-09 35.9 8.3 3.9e-08 33.3 7.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ37887.1 - 4.6e-08 32.6 1.8 0.00021 20.6 1.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ37887.1 - 0.00029 20.2 0.2 0.0014 18.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KEZ37887.1 - 0.045 14.0 2.0 0.1 12.8 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ37887.1 - 0.33 9.7 1.5 0.37 9.6 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Asp_decarbox PF02261.16 KEZ37888.1 - 4.1e-49 165.3 0.0 4.8e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Aspartate decarboxylase PQQ_2 PF13360.6 KEZ37888.1 - 0.16 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 PQQ-like domain Pantoate_ligase PF02569.15 KEZ37889.1 - 9.9e-84 280.7 0.0 1.3e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DUF2749 PF10907.8 KEZ37890.1 - 0.11 12.7 0.4 0.23 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) SAICAR_synt PF01259.18 KEZ37891.1 - 9.9e-97 323.5 0.0 1.2e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Lyase_1 PF00206.20 KEZ37892.1 - 1.8e-37 129.4 0.0 3.5e-37 128.5 0.0 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 KEZ37892.1 - 5.2e-16 59.0 0.0 1.4e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus AIRC PF00731.20 KEZ37893.1 - 8.6e-54 181.1 0.5 1e-53 180.9 0.5 1.1 1 0 0 1 1 1 1 AIR carboxylase Glyco_trans_4_4 PF13579.6 KEZ37893.1 - 0.0012 19.3 0.4 0.0021 18.5 0.4 1.3 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Chromate_transp PF02417.15 KEZ37893.1 - 0.15 12.2 3.7 0.45 10.7 0.1 2.4 1 1 1 2 2 2 0 Chromate transporter GARS_A PF01071.19 KEZ37894.1 - 3e-61 206.6 0.0 3.9e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KEZ37894.1 - 1.3e-29 102.9 0.1 2.6e-29 101.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KEZ37894.1 - 3.9e-27 94.4 1.2 3e-26 91.5 0.4 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain Adenylsucc_synt PF00709.21 KEZ37896.1 - 4.4e-173 576.0 0.0 5.1e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3151 PF11349.8 KEZ37897.1 - 2.5e-55 186.0 0.6 2.9e-55 185.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3151) TPR_4 PF07721.14 KEZ37897.1 - 0.79 10.5 19.9 2.6 8.9 0.9 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ37897.1 - 2.8 9.0 9.1 5.9 8.0 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Transglycosylas PF06737.14 KEZ37898.1 - 1.8e-22 79.8 3.5 3.3e-22 78.9 3.5 1.4 1 0 0 1 1 1 1 Transglycosylase-like domain Transglycosylas PF06737.14 KEZ37899.1 - 1.9e-20 73.3 3.3 1.9e-20 73.3 3.3 2.0 2 0 0 2 2 2 1 Transglycosylase-like domain PG_binding_1 PF01471.18 KEZ37899.1 - 2.2e-12 47.0 0.0 3.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 KEZ37899.1 - 0.0013 19.0 0.3 0.2 11.9 0.1 2.3 1 1 1 2 2 2 2 Predicted Peptidoglycan domain F_bP_aldolase PF01116.20 KEZ37900.1 - 5.5e-79 265.6 0.0 6.2e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SNARE_assoc PF09335.11 KEZ37901.1 - 5.5e-14 52.7 13.5 5.5e-14 52.7 13.5 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein CAP PF00188.26 KEZ37902.1 - 1.1e-21 77.9 0.0 1.7e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Epimerase PF01370.21 KEZ37903.1 - 8.7e-16 58.1 0.8 3.6e-14 52.8 0.8 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ37903.1 - 2.4e-07 30.2 0.1 6.4e-06 25.5 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEZ37903.1 - 4.5e-07 30.0 2.2 9.5e-07 28.9 2.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ37903.1 - 1.9e-06 27.1 0.0 2.2e-05 23.6 0.0 2.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ37903.1 - 0.0027 17.2 0.0 0.093 12.1 0.0 2.6 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_8 PF13450.6 KEZ37903.1 - 0.0081 16.4 0.2 0.053 13.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAP_B PF07930.12 KEZ37903.1 - 0.048 13.6 0.1 0.082 12.9 0.1 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B NmrA PF05368.13 KEZ37903.1 - 0.075 12.6 0.1 7.7 6.0 0.0 2.5 3 0 0 3 3 3 0 NmrA-like family adh_short PF00106.25 KEZ37903.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KEZ37903.1 - 0.18 11.0 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Acetyltransf_3 PF13302.7 KEZ37904.1 - 0.0043 17.7 0.0 0.0065 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SMODS PF18144.1 KEZ37905.1 - 5.1e-09 36.5 0.0 7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain bPH_2 PF03703.14 KEZ37906.1 - 3.7e-42 142.4 1.8 1.2e-14 54.3 0.4 3.3 3 0 0 3 3 3 3 Bacterial PH domain bPH_2 PF03703.14 KEZ37907.1 - 3.4e-14 52.8 0.0 5.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain AAA_2 PF07724.14 KEZ37908.1 - 1.7e-52 178.0 0.0 8.8e-52 175.7 0.0 2.3 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KEZ37908.1 - 7.3e-33 112.6 0.3 7.3e-33 112.6 0.3 2.3 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KEZ37908.1 - 2.3e-26 91.7 0.1 6.9e-26 90.1 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KEZ37908.1 - 6.8e-22 77.4 2.2 2.1e-12 46.9 0.2 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 KEZ37908.1 - 1.2e-21 77.5 0.2 1.5e-09 38.4 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEZ37908.1 - 4.7e-17 62.3 0.6 2.4e-12 47.0 0.0 3.7 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ37908.1 - 1.3e-10 42.0 12.6 2.7e-05 24.6 0.1 4.3 4 3 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KEZ37908.1 - 5.5e-09 36.4 0.0 0.0049 17.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KEZ37908.1 - 1.4e-08 34.7 0.0 2.7e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KEZ37908.1 - 2.1e-06 27.6 0.0 0.027 14.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEZ37908.1 - 1.3e-05 24.7 0.0 0.17 11.2 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KEZ37908.1 - 1.7e-05 25.5 2.8 0.066 13.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 KEZ37908.1 - 2.4e-05 23.8 0.0 0.027 13.9 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 KEZ37908.1 - 3.2e-05 23.5 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KEZ37908.1 - 6.2e-05 23.0 0.5 1.6 8.5 0.1 4.0 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KEZ37908.1 - 0.0002 21.9 0.2 0.4 11.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KEZ37908.1 - 0.00024 21.2 0.0 0.07 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEZ37908.1 - 0.0012 18.6 0.1 1.8 8.3 0.0 4.2 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KEZ37908.1 - 0.0013 19.0 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KEZ37908.1 - 0.0016 18.1 0.1 0.75 9.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KEZ37908.1 - 0.0019 17.9 0.0 0.57 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEZ37908.1 - 0.0024 17.8 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 KEZ37908.1 - 0.0027 16.8 0.0 0.0068 15.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 KEZ37908.1 - 0.0043 17.3 0.6 3.6 7.8 0.0 3.2 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KEZ37908.1 - 0.0048 16.8 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 KEZ37908.1 - 0.0063 16.9 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_3 PF07726.11 KEZ37908.1 - 0.0089 15.9 0.0 5.7 6.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ37908.1 - 0.0094 16.1 0.0 4 7.6 0.0 3.5 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 KEZ37908.1 - 0.012 15.6 0.0 7.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KEZ37908.1 - 0.014 14.7 0.4 0.57 9.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin ABC_tran PF00005.27 KEZ37908.1 - 0.016 15.7 0.1 1.4 9.4 0.0 2.8 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 KEZ37908.1 - 0.017 14.8 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.6 KEZ37908.1 - 0.039 13.7 0.0 0.32 10.8 0.0 2.3 3 0 0 3 3 2 0 DNA polymerase III, delta subunit DUF3572 PF12096.8 KEZ37908.1 - 0.068 13.4 1.0 33 4.8 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3572) DUF87 PF01935.17 KEZ37908.1 - 0.1 12.7 0.5 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 KEZ37908.1 - 0.12 12.0 1.1 6.9 6.2 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF737 PF05300.11 KEZ37908.1 - 0.82 10.0 4.8 1.5 9.1 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) TMF_TATA_bd PF12325.8 KEZ37908.1 - 2.2 8.5 9.6 2.4 8.4 7.7 2.0 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KEZ37908.1 - 8.4 6.9 11.5 31 5.1 11.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region MerR_1 PF13411.6 KEZ37909.1 - 9.3e-16 57.7 0.1 1.5e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ37909.1 - 7.1e-10 38.5 0.4 1.7e-09 37.3 0.4 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR_2 PF13591.6 KEZ37909.1 - 1.2e-06 28.3 0.1 1.6e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein LPP PF04728.13 KEZ37909.1 - 0.00013 22.2 1.7 0.00013 22.2 1.7 1.5 2 0 0 2 2 2 1 Lipoprotein leucine-zipper FlxA PF14282.6 KEZ37909.1 - 0.0092 16.0 0.5 0.014 15.4 0.5 1.2 1 0 0 1 1 1 1 FlxA-like protein APG6_N PF17675.1 KEZ37909.1 - 0.086 13.4 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3138 PF11336.8 KEZ37909.1 - 0.089 11.4 0.9 0.12 11.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MbeD_MobD PF04899.12 KEZ37909.1 - 0.79 9.9 4.6 2.8 8.1 4.3 1.9 1 1 1 2 2 2 0 MbeD/MobD like DnaJ_C PF01556.18 KEZ37910.1 - 2.7e-30 105.4 0.0 6.3e-30 104.2 0.0 1.6 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ37910.1 - 1.1e-25 89.5 0.4 1.6e-25 89.0 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ37910.1 - 2.5e-12 47.0 10.6 4e-12 46.3 10.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ37910.1 - 0.00039 20.3 17.0 0.0061 16.5 5.5 3.1 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 KEZ37910.1 - 0.18 12.0 16.6 2.5 8.3 0.6 4.3 3 1 0 3 3 3 0 Family of unknown function (DUF5351) Lar_restr_allev PF14354.6 KEZ37910.1 - 1.3 9.5 5.8 4.4 7.8 0.6 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.6 KEZ37910.1 - 8.1 6.4 6.5 4.5 7.2 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GrpE PF01025.19 KEZ37911.1 - 3.3e-30 104.9 0.0 4.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 GrpE Surfac_D-trimer PF09006.11 KEZ37911.1 - 0.003 17.4 0.7 0.0054 16.6 0.7 1.5 1 0 0 1 1 1 1 Lung surfactant protein D coiled-coil trimerisation Mod_r PF07200.13 KEZ37911.1 - 0.099 12.8 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HSP70 PF00012.20 KEZ37912.1 - 1.1e-246 819.7 11.3 1.7e-217 723.3 3.9 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KEZ37912.1 - 7.9e-17 61.1 4.1 1.7e-16 59.9 3.4 2.0 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 KEZ37912.1 - 0.0014 18.0 0.5 0.9 8.7 0.2 2.3 1 1 1 2 2 2 2 StbA protein TetR_C_25 PF17933.1 KEZ37912.1 - 0.023 15.0 1.8 2.3 8.6 0.0 4.0 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain FtsA PF14450.6 KEZ37912.1 - 0.098 13.1 4.2 6 7.4 0.7 4.1 2 1 0 2 2 2 0 Cell division protein FtsA DUF3269 PF11673.8 KEZ37912.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) NERD PF08378.11 KEZ37913.1 - 2.1e-08 34.6 0.0 3.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Nuclease-related domain HTH_32 PF13565.6 KEZ37913.1 - 0.28 11.8 7.1 0.83 10.3 0.0 3.8 4 0 0 4 4 4 0 Homeodomain-like domain CCG PF02754.16 KEZ37914.1 - 1.5e-36 124.4 1.1 3.8e-17 62.3 0.1 2.6 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 KEZ37914.1 - 1.9e-11 44.2 7.7 5.4e-11 42.8 6.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEZ37914.1 - 4.6e-10 39.4 12.4 1.1e-09 38.2 7.8 3.4 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ37914.1 - 1.1e-08 35.1 4.9 1.1e-08 35.1 4.9 2.9 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ37914.1 - 5.5e-07 30.0 4.6 0.017 15.7 0.1 3.0 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KEZ37914.1 - 7.6e-07 29.6 9.6 0.0011 19.5 0.2 3.0 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KEZ37914.1 - 1.2e-06 28.1 13.7 0.0018 18.0 5.3 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KEZ37914.1 - 0.00012 22.9 7.3 0.11 13.5 0.5 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KEZ37914.1 - 0.00018 21.4 11.3 0.0012 18.8 1.7 3.1 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KEZ37914.1 - 0.0019 19.0 17.1 0.016 16.1 5.3 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KEZ37914.1 - 0.0038 17.6 18.6 0.055 14.0 2.3 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KEZ37914.1 - 0.095 13.6 11.1 0.27 12.1 0.8 3.2 3 0 0 3 3 2 0 4Fe-4S dicluster domain Cation_ATPase_C PF00689.21 KEZ37914.1 - 0.27 10.9 3.2 0.11 12.2 0.7 1.6 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Fer4_15 PF13459.6 KEZ37914.1 - 0.51 11.1 5.3 5.8 7.7 0.3 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 KEZ37914.1 - 0.56 10.4 6.4 1.4 9.1 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ37914.1 - 0.89 9.7 19.3 0.4 10.8 4.0 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 KEZ37914.1 - 8.6 6.6 17.8 1.7 8.8 2.5 2.8 3 0 0 3 3 2 0 4Fe-4S dicluster domain DCD PF06559.11 KEZ37915.1 - 1.2e-16 60.5 0.0 3.2e-08 32.7 0.0 2.0 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) dUTPase PF00692.19 KEZ37915.1 - 1.8e-10 40.6 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase HAD_2 PF13419.6 KEZ37916.1 - 2.6e-12 47.2 0.0 6.9e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ37916.1 - 2.8e-12 47.4 0.4 1.8e-11 44.7 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ37916.1 - 0.00014 21.8 0.4 0.00027 20.9 0.4 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KEZ37916.1 - 0.001 19.5 0.9 0.0045 17.4 0.9 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEZ37916.1 - 0.0073 16.4 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 KEZ37916.1 - 0.039 13.8 0.0 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Glyco_hydro_65m PF03632.15 KEZ37917.1 - 1.6e-133 445.3 0.0 2e-133 445.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KEZ37917.1 - 1.6e-60 204.5 0.0 2.3e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 KEZ37917.1 - 3.5e-16 58.9 0.2 3.7e-15 55.6 0.1 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain PIG-L PF02585.17 KEZ37918.1 - 2.9e-28 99.1 0.1 5.5e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Succ_CoA_lig PF13607.6 KEZ37918.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Glycos_transf_1 PF00534.20 KEZ37919.1 - 4.7e-30 104.4 0.0 6.9e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ37919.1 - 2e-25 89.8 0.2 3.3e-25 89.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ37919.1 - 1.7e-22 80.6 7.4 1.7e-22 80.6 7.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ37919.1 - 4e-14 53.0 1.4 3.1e-13 50.1 0.2 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ37919.1 - 5.8e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ37919.1 - 0.00025 21.1 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KEZ37919.1 - 0.024 14.3 0.3 0.13 12.0 0.0 2.1 3 0 0 3 3 3 0 Starch synthase catalytic domain GATase_4 PF13230.6 KEZ37920.1 - 1.6e-20 73.2 0.0 1.9e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KEZ37920.1 - 9.5e-11 42.0 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEZ37920.1 - 0.095 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Bac_luciferase PF00296.20 KEZ37921.1 - 3.1e-17 63.0 6.0 7.6e-15 55.1 6.0 2.2 1 1 0 1 1 1 1 Luciferase-like monooxygenase Radical_SAM PF04055.21 KEZ37921.1 - 0.02 15.3 0.1 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 Radical SAM superfamily Glyco_tran_WecB PF03808.13 KEZ37921.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family UPF0052 PF01933.18 KEZ37921.1 - 0.14 11.4 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 ABC_tran PF00005.27 KEZ37922.1 - 3.7e-27 95.5 0.0 5.4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ37922.1 - 4.1e-12 46.5 0.4 1.3e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ37922.1 - 0.014 15.9 0.1 0.022 15.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KEZ37922.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEZ37922.1 - 0.039 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ37922.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF2614 PF11023.8 KEZ37922.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain ABC2_membrane_4 PF12730.7 KEZ37923.1 - 2e-05 24.6 8.3 2e-05 24.6 8.3 1.4 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KEZ37923.1 - 0.061 12.6 17.0 0.23 10.7 16.9 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Ferric_reduct PF01794.19 KEZ37923.1 - 0.39 10.8 9.0 4.9 7.3 0.7 3.1 2 1 0 3 3 3 0 Ferric reductase like transmembrane component DUF805 PF05656.14 KEZ37923.1 - 4.9 7.6 7.7 2.8 8.4 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF418 PF04235.12 KEZ37923.1 - 5.7 6.9 13.8 1.2 9.1 1.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF418) SeqA_N PF17206.3 KEZ37926.1 - 0.00019 20.7 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 SeqA protein N-terminal domain PhdYeFM_antitox PF02604.19 KEZ37927.1 - 1.4e-10 40.8 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PIN PF01850.21 KEZ37928.1 - 2.8e-12 47.2 0.2 4.1e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 PIN domain DUF5615 PF18480.1 KEZ37928.1 - 0.00041 20.0 0.2 0.0024 17.6 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF5615) DUF4411 PF14367.6 KEZ37928.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) SelB-wing_1 PF09105.10 KEZ37929.1 - 0.022 14.7 1.4 0.031 14.2 0.1 1.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Terpene_synth_C PF03936.16 KEZ37929.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain p450 PF00067.22 KEZ37930.1 - 0.0021 16.9 0.0 0.17 10.6 0.0 3.0 3 1 0 3 3 3 2 Cytochrome P450 ATP_bind_1 PF03029.17 KEZ37931.1 - 1.9e-26 93.3 0.6 5.1e-24 85.4 0.6 2.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KEZ37931.1 - 0.00015 21.3 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KEZ37931.1 - 0.00032 20.3 0.4 0.001 18.7 0.4 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEZ37931.1 - 0.0006 20.0 0.2 0.0029 17.8 0.2 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KEZ37931.1 - 0.011 16.0 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KEZ37931.1 - 0.013 15.0 0.0 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Mg_chelatase PF01078.21 KEZ37931.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 KEZ37931.1 - 0.029 14.4 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KEZ37931.1 - 0.06 13.1 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ37931.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF742 PF05331.11 KEZ37932.1 - 6.8e-31 106.4 0.0 7.6e-31 106.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) AAA_lid_2 PF17863.1 KEZ37932.1 - 0.09 12.6 0.6 0.17 11.8 0.6 1.4 1 0 0 1 1 1 0 AAA lid domain Robl_LC7 PF03259.17 KEZ37933.1 - 3.7e-22 77.9 0.2 4.7e-22 77.6 0.2 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain TetR_C_28 PF17937.1 KEZ37933.1 - 0.007 16.8 1.8 0.061 13.8 0.3 2.3 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain PhageMin_Tail PF10145.9 KEZ37933.1 - 0.035 14.0 0.5 0.047 13.5 0.5 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein HATPase_c PF02518.26 KEZ37934.1 - 1.5e-05 25.4 0.0 2.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Trp_oprn_chp PF09534.10 KEZ37934.1 - 0.033 14.0 14.5 0.037 13.8 12.4 2.1 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 KEZ37934.1 - 0.066 12.9 0.6 0.13 11.9 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3817 PF12823.7 KEZ37936.1 - 5.9e-27 94.3 2.3 8e-27 93.9 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) DUF4282 PF14110.6 KEZ37936.1 - 4.8 8.0 7.7 13 6.7 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Sigma70_r4_2 PF08281.12 KEZ37939.1 - 2.4e-12 46.3 0.0 4.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KEZ37939.1 - 2.4e-10 40.0 3.4 4e-10 39.3 3.4 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KEZ37939.1 - 6.3e-07 28.8 0.1 2e-06 27.2 0.0 2.0 3 0 0 3 3 3 1 Sigma-70, region 4 ADH_zinc_N_2 PF13602.6 KEZ37940.1 - 6.5e-20 72.5 1.3 1.5e-19 71.4 1.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ37940.1 - 1.1e-19 70.7 2.6 2e-19 69.8 2.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ37940.1 - 1.5e-06 28.1 0.1 4.1e-06 26.6 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2587 PF10759.9 KEZ37941.1 - 2.8e-71 238.2 2.8 3.6e-71 237.9 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) PmbA_TldD PF01523.16 KEZ37942.1 - 6.6e-41 141.0 0.4 9.5e-41 140.5 0.4 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 KEZ37943.1 - 1.5e-46 159.5 0.0 1.9e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Hydrolase_3 PF08282.12 KEZ37944.1 - 6.9e-48 163.6 0.0 1.1e-47 162.9 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEZ37944.1 - 2.5e-10 40.3 0.0 8.6e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 KEZ37944.1 - 5.5e-06 26.9 5.3 0.0035 17.8 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEZ37944.1 - 0.00034 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ37944.1 - 0.001 19.4 4.6 0.02 15.2 4.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PRA-PH PF01503.17 KEZ37945.1 - 0.00036 20.9 0.1 0.00048 20.5 0.1 1.3 1 1 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KEZ37945.1 - 0.01 16.0 0.1 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain HisG PF01634.18 KEZ37946.1 - 9.3e-39 133.0 0.0 1.2e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KEZ37946.1 - 2e-26 91.9 0.0 3.8e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KEZ37946.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like GTP_cyclohydroI PF01227.22 KEZ37947.1 - 7.2e-74 247.1 0.0 8.3e-74 246.9 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KEZ37947.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 QueF-like protein Peptidase_M41 PF01434.18 KEZ37948.1 - 3.3e-71 239.1 0.2 5e-71 238.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEZ37948.1 - 5.1e-45 153.1 0.0 1e-44 152.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ37948.1 - 1.3e-10 40.9 0.2 2.6e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KEZ37948.1 - 1.5e-07 31.7 0.9 1.2e-05 25.6 0.4 2.5 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 KEZ37948.1 - 0.00011 22.2 0.1 0.0014 18.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEZ37948.1 - 0.00012 21.9 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEZ37948.1 - 0.00016 22.1 0.2 0.00063 20.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KEZ37948.1 - 0.0002 20.7 0.1 0.00044 19.6 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KEZ37948.1 - 0.0023 18.2 0.1 0.072 13.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEZ37948.1 - 0.0076 16.0 0.2 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KEZ37948.1 - 0.021 14.4 1.7 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEZ37948.1 - 0.021 14.2 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEZ37948.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ37948.1 - 0.046 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KEZ37948.1 - 0.058 13.8 0.1 0.27 11.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KEZ37948.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KEZ37948.1 - 0.11 12.2 0.0 0.45 10.2 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KEZ37948.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ37948.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ37948.1 - 0.23 11.8 0.1 0.9 10.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase ATP_bind_3 PF01171.20 KEZ37950.1 - 2.4e-30 105.7 0.0 3.3e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Pribosyltran PF00156.27 KEZ37950.1 - 4e-21 75.2 0.3 7e-21 74.4 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TilS PF09179.11 KEZ37950.1 - 8.9e-07 29.3 1.4 3.7e-06 27.3 1.4 2.1 1 0 0 1 1 1 1 TilS substrate binding domain SMN PF06003.12 KEZ37950.1 - 0.27 10.5 0.7 0.41 9.9 0.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peripla_BP_3 PF13377.6 KEZ37950.1 - 3.6 7.9 8.9 1.2 9.4 0.5 3.3 3 1 0 3 3 3 0 Periplasmic binding protein-like domain Zincin_2 PF10103.9 KEZ37951.1 - 3.4e-116 388.1 4.4 3.9e-116 387.9 4.4 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_S13 PF02113.15 KEZ37952.1 - 2.4e-76 257.3 0.7 1.8e-48 165.4 0.5 2.0 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pyrophosphatase PF00719.19 KEZ37954.1 - 4.1e-50 169.7 0.0 4.7e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 KEZ37954.1 - 0.0021 17.8 0.3 0.005 16.6 0.0 1.7 2 1 0 2 2 2 1 Inorganic Pyrophosphatase Response_reg PF00072.24 KEZ37955.1 - 9.2e-30 103.1 0.0 1.3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ37955.1 - 3.7e-26 91.0 0.8 2.5e-24 85.1 0.2 2.4 2 0 0 2 2 2 2 Transcriptional regulatory protein, C terminal PSP1 PF04468.12 KEZ37956.1 - 1.9e-16 60.1 0.0 2.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region E3_binding PF02817.17 KEZ37956.1 - 0.0092 16.3 0.7 2.3 8.6 0.0 3.2 3 0 0 3 3 3 1 e3 binding domain DUF3662 PF12401.8 KEZ37956.1 - 0.11 12.9 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Glyco_trans_1_3 PF13528.6 KEZ37956.1 - 0.2 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DNA_pol3_delta2 PF13177.6 KEZ37957.1 - 1.7e-37 128.7 0.0 2.6e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KEZ37957.1 - 0.00027 21.4 0.0 0.00091 19.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KEZ37958.1 - 2.8e-41 141.2 0.0 1.3e-40 139.0 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase MFS_3 PF05977.13 KEZ37958.1 - 2.5e-21 75.7 33.7 1.2e-20 73.4 33.7 1.9 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KEZ37958.1 - 5.1e-12 45.4 48.3 5.4e-06 25.6 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_30 PF13604.6 KEZ37958.1 - 0.0018 18.0 0.7 0.0044 16.8 0.2 1.8 2 0 0 2 2 2 1 AAA domain MFS_1_like PF12832.7 KEZ37958.1 - 0.015 14.2 7.3 0.039 12.8 1.0 2.4 2 1 0 2 2 2 0 MFS_1 like family MeaB PF03308.16 KEZ37958.1 - 0.018 14.0 0.1 0.037 13.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KEZ37958.1 - 0.038 14.3 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KEZ37958.1 - 0.06 13.2 0.0 0.41 10.5 0.0 1.9 1 1 0 1 1 1 0 Deoxynucleoside kinase Topoisom_bac PF01131.20 KEZ37959.1 - 1.4e-114 383.3 0.0 2.6e-114 382.4 0.0 1.4 1 1 0 1 1 1 1 DNA topoisomerase Toprim_C_rpt PF13368.6 KEZ37959.1 - 1.1e-72 239.9 0.7 3.1e-21 75.1 0.1 4.5 3 1 1 4 4 4 4 Topoisomerase C-terminal repeat Toprim PF01751.22 KEZ37959.1 - 4.7e-27 94.2 0.0 9e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 KEZ37959.1 - 0.0023 18.4 0.0 0.0065 16.9 0.0 1.8 1 0 0 1 1 1 1 Toprim domain H_PPase PF03030.16 KEZ37961.1 - 9.5e-238 791.1 42.9 1.2e-237 790.8 42.9 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase HATPase_c_2 PF13581.6 KEZ37962.1 - 2.3e-38 131.0 0.1 4e-38 130.2 0.1 1.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain STAS PF01740.21 KEZ37963.1 - 1.1e-18 67.0 0.0 1.2e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KEZ37963.1 - 7e-15 55.1 0.1 9.2e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 STAS domain DEAD PF00270.29 KEZ37964.1 - 4.2e-23 82.0 0.0 6.6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KEZ37964.1 - 1.4e-19 70.6 0.1 4.9e-19 68.9 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KEZ37964.1 - 2.8e-11 43.7 0.0 1.2e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 KEZ37964.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MASE1 PF05231.14 KEZ37965.1 - 0.012 14.8 0.5 0.016 14.4 0.5 1.2 1 0 0 1 1 1 0 MASE1 TadE PF07811.12 KEZ37966.1 - 2.5e-05 24.4 4.9 4.7e-05 23.6 4.9 1.5 1 0 0 1 1 1 1 TadE-like protein ATG22 PF11700.8 KEZ37966.1 - 0.16 10.5 0.0 0.19 10.3 0.0 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like COX8 PF02285.15 KEZ37966.1 - 0.17 11.8 2.0 0.41 10.6 2.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII DUF4244 PF14029.6 KEZ37967.1 - 8.5e-23 79.6 1.4 1.1e-22 79.2 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4244) T2SSF PF00482.23 KEZ37968.1 - 7.7e-09 35.6 5.6 7.7e-09 35.6 5.6 3.5 3 1 0 3 3 3 2 Type II secretion system (T2SS), protein F HrpJ PF07201.11 KEZ37968.1 - 8.9 6.6 7.4 1.2 9.4 0.8 2.1 2 0 0 2 2 2 0 HrpJ-like domain T2SSE PF00437.20 KEZ37969.1 - 1.2e-72 244.3 0.3 1.5e-72 243.9 0.3 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KEZ37969.1 - 5.5e-05 23.6 0.3 0.00013 22.4 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KEZ37969.1 - 6.1e-05 23.6 0.0 9.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KEZ37969.1 - 0.00078 19.1 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 KEZ37969.1 - 0.0015 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KEZ37969.1 - 0.0015 18.8 0.1 0.0038 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KEZ37969.1 - 0.0029 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KEZ37969.1 - 0.0084 15.8 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEZ37969.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin FtsK_SpoIIIE PF01580.18 KEZ37969.1 - 0.011 15.1 0.4 0.03 13.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 KEZ37969.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KEZ37969.1 - 0.031 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KEZ37969.1 - 0.038 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 KEZ37969.1 - 0.041 14.4 0.8 0.062 13.8 0.8 1.1 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KEZ37969.1 - 0.071 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.18 KEZ37969.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 KEZ37969.1 - 0.079 13.1 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase MukB PF04310.12 KEZ37969.1 - 0.093 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA_7 PF12775.7 KEZ37969.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KEZ37969.1 - 0.13 12.1 1.1 0.22 11.4 0.3 1.8 2 1 1 3 3 2 0 RsgA GTPase AAA_21 PF13304.6 KEZ37969.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system CbiA PF01656.23 KEZ37969.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 KEZ37969.1 - 0.2 11.5 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KEZ37969.1 - 0.21 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KEZ37970.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KEZ37970.1 - 0.00089 18.8 3.1 0.0011 18.5 0.3 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KEZ37970.1 - 0.029 14.3 0.3 0.086 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KEZ37970.1 - 0.056 12.9 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 KEZ37970.1 - 0.093 12.0 0.8 5 6.3 0.4 2.1 2 0 0 2 2 2 0 ATPase MipZ ArsA_ATPase PF02374.15 KEZ37970.1 - 0.12 11.5 0.3 0.21 10.7 0.3 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase CBP_BcsQ PF06564.12 KEZ37970.1 - 0.15 11.5 3.2 0.26 10.7 2.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ NAD_binding_8 PF13450.6 KEZ37970.1 - 0.17 12.2 0.7 4.2 7.7 0.7 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain CobW_C PF07683.14 KEZ37971.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Phage_holin_3_6 PF07332.11 KEZ37972.1 - 8.4e-28 96.7 10.9 9.9e-28 96.4 10.9 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 KEZ37972.1 - 0.51 10.2 5.9 0.72 9.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2207 PF09972.9 KEZ37972.1 - 0.75 8.5 2.1 0.89 8.2 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 KEZ37973.1 - 3.1e-22 79.5 0.2 6.6e-22 78.4 0.3 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ37973.1 - 3.9e-20 73.4 19.5 5.4e-20 72.9 19.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ37973.1 - 5.9e-11 42.1 0.1 1.3e-10 40.9 0.1 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KEZ37973.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase Trypsin_2 PF13365.6 KEZ37974.1 - 9.9e-22 78.4 0.9 2.3e-21 77.3 0.9 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Colicin_V PF02674.16 KEZ37974.1 - 1.6e-19 70.3 10.2 2.6e-19 69.6 10.2 1.3 1 0 0 1 1 1 1 Colicin V production protein Trypsin PF00089.26 KEZ37974.1 - 6.7e-07 29.3 0.0 2.5e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 KEZ37974.1 - 0.027 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S55 PF05580.12 KEZ37974.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 SpoIVB peptidase S55 Cupredoxin_1 PF13473.6 KEZ37975.1 - 7.6e-05 22.8 0.0 9.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 KEZ37975.1 - 0.00029 21.2 0.0 0.00072 20.0 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family NUDIX PF00293.28 KEZ37976.1 - 7.5e-10 39.0 0.1 1.4e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 KEZ37977.1 - 3.4e-16 59.6 0.0 5.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KEZ37977.1 - 1.7e-08 33.9 0.0 5e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KEZ37977.1 - 0.0031 17.8 4.8 0.0052 17.1 4.8 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III cNMP_binding PF00027.29 KEZ37979.1 - 4.1e-25 87.7 0.0 6.4e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 KEZ37979.1 - 4.2e-17 61.9 2.0 4.6e-17 61.8 0.4 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 KEZ37979.1 - 0.00017 21.1 0.1 0.00037 20.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family GntR PF00392.21 KEZ37979.1 - 0.00027 20.5 2.3 0.00047 19.7 0.3 2.3 3 0 0 3 3 2 1 Bacterial regulatory proteins, gntR family HTH_3 PF01381.22 KEZ37979.1 - 0.00037 20.5 0.1 0.0011 18.9 0.0 1.8 2 0 0 2 2 1 1 Helix-turn-helix Sigma70_r4 PF04545.16 KEZ37979.1 - 0.001 18.6 0.0 0.004 16.7 0.0 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_31 PF13560.6 KEZ37979.1 - 0.0019 18.5 3.0 0.0068 16.7 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ37979.1 - 0.002 17.6 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KEZ37979.1 - 0.0023 17.9 1.4 0.0037 17.2 0.4 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_36 PF13730.6 KEZ37979.1 - 0.003 17.5 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ37979.1 - 0.0048 16.8 3.9 0.016 15.1 0.3 2.8 3 0 0 3 3 2 1 MarR family HemN_C PF06969.16 KEZ37979.1 - 0.0099 15.9 0.4 0.032 14.3 0.2 1.9 2 0 0 2 2 2 1 HemN C-terminal domain HTH_23 PF13384.6 KEZ37979.1 - 0.025 14.4 0.0 0.091 12.6 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KEZ37979.1 - 0.027 14.1 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_19 PF12844.7 KEZ37979.1 - 0.029 14.4 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 KEZ37979.1 - 0.038 13.8 1.1 1 9.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_28 PF13518.6 KEZ37979.1 - 0.049 13.8 0.7 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 KEZ37979.1 - 0.061 13.3 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 KEZ37979.1 - 0.065 13.0 1.6 0.44 10.4 0.1 2.7 2 1 1 3 3 3 0 IclR helix-turn-helix domain TPR_12 PF13424.6 KEZ37980.1 - 2.7e-22 78.8 56.4 2.9e-10 40.3 12.1 7.2 6 1 0 6 6 6 5 Tetratricopeptide repeat Guanylate_cyc PF00211.20 KEZ37980.1 - 6.6e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KEZ37980.1 - 3.5e-17 63.3 1.0 3.5e-17 63.3 1.0 3.6 4 0 0 4 4 3 1 AAA ATPase domain TPR_MalT PF17874.1 KEZ37980.1 - 4.6e-17 62.4 45.2 8.5e-06 25.4 3.9 6.0 3 1 4 7 7 7 5 MalT-like TPR region TPR_8 PF13181.6 KEZ37980.1 - 3.3e-08 33.1 12.9 2.4 8.6 0.1 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ37980.1 - 3.7e-08 32.9 52.9 0.029 14.5 2.9 11.6 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ37980.1 - 0.00016 22.1 3.4 0.00016 22.1 3.4 7.9 5 2 5 10 10 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ37980.1 - 0.00024 20.8 19.6 0.42 10.5 1.2 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ37980.1 - 0.0003 21.0 5.0 2.7 8.3 0.0 5.3 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KEZ37980.1 - 0.0006 20.4 95.2 0.031 15.1 0.6 14.2 8 3 6 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ37980.1 - 0.0023 18.6 7.9 0.0023 18.6 7.9 10.2 8 2 3 11 11 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ37980.1 - 0.0038 17.1 3.9 0.0038 17.1 3.9 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat DZR PF12773.7 KEZ37980.1 - 0.0054 16.7 0.4 0.01 15.8 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon TPR_7 PF13176.6 KEZ37980.1 - 0.015 15.2 20.6 1.6 8.9 0.5 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KEZ37980.1 - 0.026 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 KEZ37980.1 - 0.05 13.9 0.3 0.55 10.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain ANAPC5 PF12862.7 KEZ37980.1 - 0.14 12.2 0.1 2.1 8.5 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 zf-ribbon_3 PF13248.6 KEZ37980.1 - 0.18 11.3 1.1 0.32 10.5 1.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TPR_11 PF13414.6 KEZ37980.1 - 0.38 10.5 15.6 20 5.0 0.5 5.4 5 0 0 5 5 5 0 TPR repeat Wzy_C_2 PF11846.8 KEZ37980.1 - 0.54 10.1 14.5 10 6.0 0.8 4.9 4 1 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Lactamase_B PF00753.27 KEZ37981.1 - 1.2e-14 54.7 14.4 1.8e-10 41.2 7.7 3.8 3 1 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ37981.1 - 5.9e-07 29.2 1.0 5.9e-07 29.2 1.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEZ37981.1 - 4.3e-05 23.5 0.0 6.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KEZ37981.1 - 4.7e-05 23.3 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_6 PF16661.5 KEZ37981.1 - 0.084 12.3 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain NUDIX PF00293.28 KEZ37982.1 - 3.1e-06 27.3 0.4 0.055 13.5 0.1 3.1 1 1 1 2 2 2 2 NUDIX domain YjgF_endoribonc PF14588.6 KEZ37983.1 - 2.3e-31 109.0 1.2 2.7e-31 108.7 1.2 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 KEZ37983.1 - 2.4e-19 69.5 0.0 3.3e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4177 PF13783.6 KEZ37984.1 - 8.1e-06 26.0 0.0 1.8e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4177) ArsA_ATPase PF02374.15 KEZ37985.1 - 9.8e-21 74.2 0.0 4.7e-17 62.1 0.0 2.2 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 KEZ37985.1 - 8.5e-09 35.5 0.1 2.7e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KEZ37985.1 - 5.7e-07 29.6 0.0 1.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 KEZ37985.1 - 1.2e-05 24.9 0.3 7.6e-05 22.3 0.2 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 KEZ37985.1 - 0.00013 21.6 0.2 0.00028 20.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KEZ37985.1 - 0.00035 20.0 0.1 0.00073 18.9 0.1 1.5 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 KEZ37985.1 - 0.0011 18.5 0.2 0.0041 16.6 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_30 PF13604.6 KEZ37985.1 - 0.0022 17.8 0.9 0.0022 17.8 0.9 1.8 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 KEZ37985.1 - 0.01 15.3 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 KEZ37985.1 - 0.017 15.5 0.2 0.044 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KEZ37985.1 - 0.018 14.8 0.3 0.047 13.4 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein VirC1 PF07015.11 KEZ37985.1 - 0.026 13.8 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein T2SSE PF00437.20 KEZ37985.1 - 0.037 13.1 0.5 0.2 10.7 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF3048 PF11258.8 KEZ37985.1 - 0.056 13.5 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain AAA_18 PF13238.6 KEZ37985.1 - 0.072 13.6 0.3 0.072 13.6 0.3 2.1 2 1 0 2 2 1 0 AAA domain NACHT PF05729.12 KEZ37985.1 - 0.093 12.6 0.9 0.16 11.9 0.9 1.3 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 KEZ37985.1 - 0.097 12.1 0.3 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 PhoH-like protein Thymidylate_kin PF02223.17 KEZ37985.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase SRP54 PF00448.22 KEZ37985.1 - 0.16 11.6 0.7 0.31 10.6 0.7 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KEZ37985.1 - 0.16 11.2 0.2 0.22 10.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KEZ37985.1 - 0.48 10.2 1.8 0.6 9.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 KEZ37986.1 - 4.4e-26 91.8 0.0 4.1e-25 88.6 0.0 2.0 1 1 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KEZ37986.1 - 2.4e-08 34.1 0.0 3.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KEZ37986.1 - 2.6e-08 34.0 0.0 5.6e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KEZ37986.1 - 8.3e-08 32.0 0.0 0.00024 20.7 0.0 3.1 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase MeaB PF03308.16 KEZ37986.1 - 1.5e-05 24.1 0.2 0.002 17.2 0.1 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KEZ37986.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein SRP54 PF00448.22 KEZ37986.1 - 0.0002 21.1 0.2 0.00045 19.9 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.16 KEZ37986.1 - 0.00028 20.4 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 KEZ37986.1 - 0.00092 19.0 0.3 0.0024 17.6 0.3 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KEZ37986.1 - 0.0031 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 KEZ37986.1 - 0.0032 17.9 0.6 0.046 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 KEZ37986.1 - 0.0041 17.0 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase ATP_bind_1 PF03029.17 KEZ37986.1 - 0.0042 16.9 0.0 0.009 15.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein YjeF_N PF03853.15 KEZ37986.1 - 0.0048 16.8 0.2 0.011 15.7 0.2 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus AAA_22 PF13401.6 KEZ37986.1 - 0.0049 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KEZ37986.1 - 0.0057 16.3 1.3 0.019 14.5 1.3 2.0 1 1 0 1 1 1 1 AAA domain CobA_CobO_BtuR PF02572.15 KEZ37986.1 - 0.0073 16.6 0.2 0.017 15.4 0.2 1.6 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Methyltransf_24 PF13578.6 KEZ37986.1 - 0.0093 17.0 0.5 0.059 14.4 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Zeta_toxin PF06414.12 KEZ37986.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.11 KEZ37986.1 - 0.015 14.6 0.3 0.31 10.3 0.1 2.4 1 1 0 2 2 2 0 ATPase MipZ AAA_33 PF13671.6 KEZ37986.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ37986.1 - 0.029 14.6 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain CBP_BcsQ PF06564.12 KEZ37986.1 - 0.048 13.1 0.2 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KEZ37986.1 - 0.05 13.4 0.0 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KEZ37986.1 - 0.061 12.8 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family LpxK PF02606.14 KEZ37986.1 - 0.075 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase CLP1_P PF16575.5 KEZ37986.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DEAD PF00270.29 KEZ37986.1 - 0.17 11.6 0.0 0.57 9.9 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase KTI12 PF08433.10 KEZ37986.1 - 0.26 10.7 0.0 0.44 9.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Whib PF02467.16 KEZ37987.1 - 2.3e-19 69.8 2.2 3.1e-19 69.3 2.2 1.2 1 0 0 1 1 1 1 Transcription factor WhiB Transgly PF00912.22 KEZ37988.1 - 1.5e-62 210.2 0.1 2.3e-62 209.6 0.1 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KEZ37988.1 - 1e-26 93.9 0.0 1.7e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PASTA PF03793.19 KEZ37988.1 - 2.4e-11 43.3 0.6 7.9e-11 41.7 0.2 2.2 2 0 0 2 2 2 1 PASTA domain DUF2613 PF11021.8 KEZ37988.1 - 0.53 10.4 8.5 1.8 8.7 8.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) YqeY PF09424.10 KEZ37989.1 - 7.8e-44 149.2 0.8 8.7e-44 149.1 0.8 1.0 1 0 0 1 1 1 1 Yqey-like protein Metallophos PF00149.28 KEZ37990.1 - 1.6e-08 35.3 0.0 2.9e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ37990.1 - 1.4e-07 31.8 0.0 2.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phage_int_SAM_3 PF14659.6 KEZ37991.1 - 6.4e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 KEZ37991.1 - 2.1e-09 37.4 0.0 8e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family HTH_17 PF12728.7 KEZ37992.1 - 2.8e-08 33.8 0.1 3.9e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain AsmA_2 PF13502.6 KEZ37993.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 AsmA-like C-terminal region Methyltransf_19 PF04672.12 KEZ37994.1 - 9.6e-47 159.7 0.0 1.1e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase DUF4733 PF15878.5 KEZ37995.1 - 0.025 15.1 0.1 11 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) Helitron_like_N PF14214.6 KEZ37995.1 - 0.13 12.5 0.1 0.33 11.1 0.1 1.7 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus HTH_17 PF12728.7 KEZ37996.1 - 1.2e-16 60.6 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ37996.1 - 5.6e-05 22.8 0.0 8.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain AbiEi_4 PF13338.6 KEZ37996.1 - 0.00031 20.8 0.1 0.00073 19.6 0.0 1.7 1 1 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin HTH_29 PF13551.6 KEZ37996.1 - 0.00065 19.7 0.1 0.0011 18.9 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_IclR PF09339.10 KEZ37996.1 - 0.00069 19.4 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_3 PF01381.22 KEZ37996.1 - 0.0016 18.5 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix HTH_8 PF02954.19 KEZ37996.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 KEZ37996.1 - 0.0018 18.6 0.2 0.006 16.9 0.2 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_22 PF13309.6 KEZ37996.1 - 0.0078 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 KEZ37996.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 KEZ37996.1 - 0.031 14.2 0.0 0.046 13.7 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ37996.1 - 0.032 14.2 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF134 PF02001.16 KEZ37996.1 - 0.036 14.6 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF134 UPF0175 PF03683.13 KEZ37996.1 - 0.049 13.3 0.0 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0175) HTH_7 PF02796.15 KEZ37996.1 - 0.058 13.5 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TrmB PF01978.19 KEZ37996.1 - 0.059 13.3 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_AlpA PF05930.12 KEZ37996.1 - 0.062 13.1 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Sigma70_r4 PF04545.16 KEZ37997.1 - 0.0048 16.4 0.1 0.0063 16.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.13 KEZ37997.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_17 PF12728.7 KEZ37997.1 - 0.018 15.2 0.1 0.059 13.6 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KEZ37997.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 KEZ37997.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 KEZ37997.1 - 0.061 13.1 0.0 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain KORA PF16509.5 KEZ37997.1 - 0.072 13.4 0.1 0.14 12.5 0.1 1.4 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor TrmB PF01978.19 KEZ37997.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_AlpA PF05930.12 KEZ37997.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 1 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_AsnC-type PF13404.6 KEZ37997.1 - 0.14 12.0 0.2 0.65 9.9 0.1 1.9 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain Phage_integrase PF00589.22 KEZ38000.1 - 4e-22 78.8 0.1 1e-21 77.5 0.1 1.7 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KEZ38000.1 - 7e-06 26.2 0.0 1.8e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain MFS_1 PF07690.16 KEZ38001.1 - 5.2e-11 42.1 53.4 6.5e-10 38.5 44.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LysM PF01476.20 KEZ38002.1 - 1.2e-05 25.3 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 LysM domain BTAD PF03704.17 KEZ38002.1 - 0.00036 21.0 1.3 0.00064 20.2 1.3 1.5 1 0 0 1 1 1 1 Bacterial transcriptional activator domain DUF3389 PF11869.8 KEZ38003.1 - 0.16 12.2 0.1 0.19 12.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3389) WXG100 PF06013.12 KEZ38004.1 - 0.0015 18.8 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DASH_Hsk3 PF08227.11 KEZ38004.1 - 0.035 14.5 2.2 0.049 14.0 2.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF4140 PF13600.6 KEZ38004.1 - 0.061 13.8 0.2 0.061 13.8 0.2 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Gon7 PF08738.10 KEZ38004.1 - 0.064 13.3 0.1 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 Gon7 family NPV_P10 PF05531.12 KEZ38004.1 - 0.13 12.8 0.3 0.31 11.5 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.12 KEZ38005.1 - 6.4e-07 29.5 0.1 7.2e-07 29.3 0.1 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG BPA_C PF18040.1 KEZ38005.1 - 0.068 13.1 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 beta porphyranase A C-terminal FtsK_SpoIIIE PF01580.18 KEZ38006.1 - 8.8e-61 205.3 0.0 2.7e-31 108.8 0.0 4.2 4 0 0 4 4 4 3 FtsK/SpoIIIE family AAA_22 PF13401.6 KEZ38006.1 - 4.4e-09 36.7 0.0 0.0085 16.4 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 KEZ38006.1 - 1.2e-08 35.5 5.1 0.005 17.2 0.1 4.3 3 1 0 3 3 3 3 AAA ATPase domain AAA_29 PF13555.6 KEZ38006.1 - 0.00095 18.9 0.2 0.22 11.3 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain YukD PF08817.10 KEZ38006.1 - 0.017 15.8 0.3 0.077 13.7 0.3 2.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ABC_tran PF00005.27 KEZ38006.1 - 0.029 14.9 0.0 4.4 7.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.9 KEZ38006.1 - 0.044 12.7 0.2 3.4 6.5 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.15 KEZ38006.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein GGDEF PF00990.21 KEZ38007.1 - 6e-13 48.9 0.0 7.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain BON PF04972.17 KEZ38007.1 - 0.0055 17.0 0.0 0.023 15.0 0.0 1.9 1 1 1 2 2 2 1 BON domain GGDEF_2 PF17853.1 KEZ38007.1 - 0.045 14.0 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 GGDEF-like domain RyR PF02026.16 KEZ38008.1 - 2.5e-19 69.3 0.0 1e-13 51.3 0.0 2.3 2 0 0 2 2 2 2 RyR domain TrkA_N PF02254.18 KEZ38008.1 - 9.4e-18 64.6 0.2 2.3e-10 40.7 0.1 3.1 2 1 0 2 2 2 2 TrkA-N domain Pyr_redox_2 PF07992.14 KEZ38008.1 - 1.2e-05 24.7 0.1 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ38008.1 - 9.7e-05 22.4 0.1 0.026 14.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEZ38008.1 - 0.00057 20.4 0.1 0.72 10.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ38008.1 - 0.014 15.6 0.0 0.083 13.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3572 PF12096.8 KEZ38009.1 - 0.11 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) Glycos_transf_1 PF00534.20 KEZ38010.1 - 0.0076 15.8 0.0 0.0082 15.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ38010.1 - 0.032 14.7 0.0 0.036 14.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 tRNA-synt_2 PF00152.20 KEZ38011.1 - 5.4e-69 232.7 0.0 6.4e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEZ38011.1 - 2.2e-11 43.5 1.0 3.5e-11 42.9 0.4 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEZ38011.1 - 0.0065 16.0 0.2 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FTA4 PF13093.6 KEZ38011.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 rve_3 PF13683.6 KEZ38012.1 - 1.6e-13 50.2 0.1 2.5e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 KEZ38012.1 - 7.5e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Phage_integrase PF00589.22 KEZ38013.1 - 0.00087 19.1 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family HD PF01966.22 KEZ38014.1 - 1.2e-09 38.4 0.8 2.7e-09 37.3 0.8 1.6 1 0 0 1 1 1 1 HD domain ACT PF01842.25 KEZ38014.1 - 5.9e-08 32.3 3.5 0.00063 19.5 0.3 3.0 2 0 0 2 2 2 2 ACT domain GlnD_UR_UTase PF08335.11 KEZ38014.1 - 3.2e-07 30.5 0.1 9.3e-05 22.6 0.0 2.5 1 1 1 2 2 2 2 GlnD PII-uridylyltransferase GlnE PF03710.15 KEZ38014.1 - 0.017 14.5 1.0 0.028 13.8 0.0 1.8 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase ACT_6 PF13740.6 KEZ38014.1 - 0.055 13.5 2.7 7.3 6.7 0.2 2.8 2 0 0 2 2 2 0 ACT domain DUF294 PF03445.13 KEZ38014.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 ACT_4 PF13291.6 KEZ38014.1 - 0.17 12.5 0.6 29 5.3 0.0 2.4 2 0 0 2 2 2 0 ACT domain NTP_transf_2 PF01909.23 KEZ38014.1 - 0.23 11.8 0.6 0.67 10.3 0.1 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain P-II PF00543.22 KEZ38015.1 - 1.6e-41 141.0 2.3 1.8e-41 140.8 2.3 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 KEZ38015.1 - 0.018 15.1 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Ammonium_transp PF00909.21 KEZ38016.1 - 2.1e-127 425.1 36.8 2.4e-127 425.0 36.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF872 PF05915.12 KEZ38016.1 - 0.72 10.0 3.3 2.6 8.3 3.3 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) NLPC_P60 PF00877.19 KEZ38017.1 - 3.3e-23 81.7 0.0 6.7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family LRAT PF04970.13 KEZ38017.1 - 0.13 12.5 0.2 0.63 10.4 0.1 2.0 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF4472 PF14739.6 KEZ38017.1 - 6.7 7.5 6.0 3.4 8.4 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Fe_dep_repr_C PF02742.15 KEZ38018.1 - 3.3e-26 91.2 0.1 5.7e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 KEZ38018.1 - 1.1e-12 48.0 0.0 6.6e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 KEZ38018.1 - 2.3e-05 24.2 1.0 0.0071 16.2 0.2 2.6 2 0 0 2 2 2 2 MarR family HTH_27 PF13463.6 KEZ38018.1 - 0.00071 20.0 0.0 0.004 17.6 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain FeoA PF04023.14 KEZ38018.1 - 0.0026 18.0 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 FeoA domain MarR PF01047.22 KEZ38018.1 - 0.0054 16.6 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 KEZ38018.1 - 0.017 15.5 0.0 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator GntR PF00392.21 KEZ38018.1 - 0.089 12.5 0.9 0.25 11.0 0.2 2.1 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF3039 PF11238.8 KEZ38019.1 - 5.3e-24 83.7 0.1 6.2e-24 83.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) Zn-ribbon_8 PF09723.10 KEZ38019.1 - 0.01 15.9 0.3 0.018 15.2 0.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-HC3 PF16827.5 KEZ38019.1 - 0.069 13.4 0.1 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 zinc-finger zf-AD PF07776.15 KEZ38019.1 - 0.11 12.8 0.1 0.11 12.7 0.1 1.3 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Sulfate_transp PF00916.20 KEZ38020.1 - 1.7e-67 227.9 25.9 2.1e-67 227.5 25.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEZ38020.1 - 4.2e-14 52.2 0.1 1.1e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 STAS domain HCO3_cotransp PF00955.21 KEZ38020.1 - 0.0018 17.2 2.0 0.59 8.9 0.2 2.2 2 0 0 2 2 2 2 HCO3- transporter family DUF2111 PF09884.9 KEZ38020.1 - 0.039 14.0 0.5 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) CRM1_repeat PF18777.1 KEZ38020.1 - 0.2 11.2 0.0 0.51 9.9 0.0 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Troponin-I_N PF11636.8 KEZ38020.1 - 0.3 11.0 2.2 0.84 9.6 2.2 1.7 1 0 0 1 1 1 0 Troponin I residues 1-32 HTH_20 PF12840.7 KEZ38021.1 - 2.6e-11 43.4 2.3 3.5e-11 43.0 0.1 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 KEZ38021.1 - 7.8e-11 41.7 0.1 2.2e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KEZ38021.1 - 0.00017 21.4 1.4 0.00066 19.5 0.2 2.2 2 1 0 2 2 2 1 MarR family TrmB PF01978.19 KEZ38021.1 - 0.0033 17.3 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 KEZ38021.1 - 0.0072 16.7 0.2 0.029 14.7 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 KEZ38021.1 - 0.031 13.8 0.1 0.065 12.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 KEZ38021.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 MarR family HxlR PF01638.17 KEZ38021.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 HxlR-like helix-turn-helix HTH_9 PF08221.11 KEZ38021.1 - 0.15 12.2 0.1 0.32 11.1 0.0 1.5 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Chromate_transp PF02417.15 KEZ38022.1 - 5.5 7.1 5.9 0.7 10.0 1.7 1.7 2 0 0 2 2 2 0 Chromate transporter DHquinase_II PF01220.19 KEZ38023.1 - 5.8e-46 155.6 0.0 6.5e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II DUF2110 PF09883.9 KEZ38023.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) DegT_DnrJ_EryC1 PF01041.17 KEZ38024.1 - 6.9e-112 374.3 0.0 7.8e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KEZ38024.1 - 4e-08 32.8 0.0 7.8e-08 31.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ38024.1 - 0.0013 17.4 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KEZ38024.1 - 0.0073 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GFO_IDH_MocA PF01408.22 KEZ38025.1 - 3.6e-20 73.0 0.0 6.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KEZ38025.1 - 7.9e-07 29.5 0.0 2.2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 KEZ38025.1 - 9.8e-05 22.3 0.1 0.0002 21.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 KEZ38025.1 - 0.00025 21.7 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.6 KEZ38025.1 - 0.091 13.3 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain HAD_2 PF13419.6 KEZ38026.1 - 6.3e-32 111.1 0.0 7.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ38026.1 - 6.2e-19 69.1 0.2 5e-18 66.1 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ38026.1 - 4.4e-11 42.7 0.9 8e-11 41.9 0.3 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KEZ38026.1 - 4.6e-08 33.7 0.0 8.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ38026.1 - 0.04 13.7 0.0 16 5.1 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEZ38026.1 - 0.051 13.7 0.0 0.31 11.2 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ROK PF00480.20 KEZ38027.1 - 1.9e-37 129.4 0.9 5.9e-36 124.4 0.1 2.0 2 0 0 2 2 2 2 ROK family Shikimate_dh_N PF08501.11 KEZ38028.1 - 2.5e-15 56.5 0.0 3.7e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain ThiF PF00899.21 KEZ38028.1 - 0.00058 19.3 0.1 0.00094 18.6 0.1 1.2 1 0 0 1 1 1 1 ThiF family PreAtp-grasp PF18604.1 KEZ38028.1 - 0.039 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Pre ATP-grasp domain Shikimate_DH PF01488.20 KEZ38028.1 - 0.044 13.9 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ38028.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KEZ38028.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHQ_synthase PF01761.20 KEZ38029.1 - 1.2e-79 267.1 0.1 1.2e-78 263.9 0.1 1.9 1 1 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KEZ38029.1 - 1.4e-07 31.4 0.2 1.2e-06 28.5 0.0 2.2 1 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KEZ38029.1 - 1.1e-05 24.5 0.7 5.8e-05 22.1 0.1 2.3 1 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase MarR PF01047.22 KEZ38030.1 - 6.3e-12 45.3 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KEZ38030.1 - 4e-11 42.6 2.0 6e-11 42.1 0.5 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KEZ38030.1 - 4.6e-07 30.2 0.1 8.8e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 KEZ38030.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 KEZ38030.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 KEZ38030.1 - 0.0023 17.5 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 KEZ38030.1 - 0.003 17.7 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KEZ38030.1 - 0.0088 15.8 0.2 0.0088 15.8 0.2 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 KEZ38030.1 - 0.012 15.6 0.9 0.031 14.3 0.9 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2250 PF10007.9 KEZ38030.1 - 0.031 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_11 PF08279.12 KEZ38030.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain DUF4423 PF14394.6 KEZ38030.1 - 0.2 11.3 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Glyoxalase_4 PF13669.6 KEZ38031.1 - 3.3e-15 56.3 0.0 4.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KEZ38031.1 - 0.0028 17.8 0.1 0.026 14.6 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KEZ38031.1 - 0.053 13.7 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Trp_halogenase PF04820.14 KEZ38032.1 - 2.6e-14 53.0 1.3 4.3e-06 25.8 0.1 2.7 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KEZ38032.1 - 2e-08 33.9 0.6 2.3e-07 30.4 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ38032.1 - 7e-07 29.4 0.5 2.1e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ38032.1 - 9.7e-07 28.3 0.0 5.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ38032.1 - 1.4e-05 24.9 4.6 0.023 14.3 4.6 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ38032.1 - 0.00017 20.8 0.4 0.18 10.8 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein 3HCDH_N PF02737.18 KEZ38032.1 - 0.00095 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KEZ38032.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 KEZ38032.1 - 0.0041 17.6 0.1 0.0079 16.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEZ38032.1 - 0.006 16.2 0.3 0.013 15.2 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KEZ38032.1 - 0.033 13.3 0.2 0.059 12.5 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KEZ38032.1 - 0.044 13.4 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KEZ38032.1 - 0.057 14.0 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 KEZ38032.1 - 0.059 12.1 0.0 0.41 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KEZ38032.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Metal_resist PF13801.6 KEZ38033.1 - 0.15 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance SelA PF03841.13 KEZ38034.1 - 9.9e-84 281.4 0.0 3.1e-81 273.2 0.0 2.1 2 0 0 2 2 2 2 L-seryl-tRNA selenium transferase STAS_2 PF13466.6 KEZ38036.1 - 5.3e-14 52.3 1.0 7e-14 51.9 1.0 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KEZ38036.1 - 5.2e-12 45.4 0.1 6.5e-12 45.1 0.1 1.0 1 0 0 1 1 1 1 STAS domain Acetyltransf_1 PF00583.25 KEZ38037.1 - 2.6e-20 72.8 0.0 4.2e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ38037.1 - 2e-13 50.6 0.3 9.6e-06 25.9 0.1 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ38037.1 - 5.2e-12 45.6 0.0 4.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 KEZ38037.1 - 1.1e-09 38.3 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ38037.1 - 1.8e-05 24.8 0.1 0.27 11.3 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ38037.1 - 0.00059 20.5 0.1 1.4 9.6 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEZ38037.1 - 0.013 15.7 0.2 0.71 10.1 0.1 2.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Trans_reg_C PF00486.28 KEZ38038.1 - 1.6e-28 98.5 0.0 2.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal ThiS PF02597.20 KEZ38040.1 - 5.3e-10 39.8 0.0 6.3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family Thioredoxin PF00085.20 KEZ38043.1 - 3.9e-07 30.0 0.0 4.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEZ38043.1 - 2e-05 25.0 0.0 0.0006 20.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 KEZ38043.1 - 0.0041 17.3 0.0 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_8 PF13905.6 KEZ38043.1 - 0.0071 16.6 0.0 3.1 8.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KEZ38043.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 KEZ38043.1 - 0.25 11.1 0.0 0.3 10.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Rhodanese PF00581.20 KEZ38044.1 - 2.1e-35 121.5 0.1 3.8e-17 62.7 0.1 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Sorting_nexin PF03700.13 KEZ38044.1 - 0.15 12.6 0.0 0.28 11.8 0.0 1.5 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain DUF1416 PF07210.12 KEZ38045.1 - 1.8e-32 111.1 0.5 2e-32 110.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1416) CarboxypepD_reg PF13620.6 KEZ38045.1 - 0.00043 20.5 1.0 0.00052 20.2 1.0 1.1 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SH3_7 PF12914.7 KEZ38045.1 - 0.0061 16.7 0.0 0.018 15.2 0.0 1.8 1 1 1 2 2 2 1 SH3 domain of SH3b2 type DUF1794 PF08768.11 KEZ38047.1 - 9.6e-49 165.2 0.0 1.1e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) DrsE PF02635.15 KEZ38049.1 - 3.1e-10 40.5 0.0 3.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family YbjN PF10722.9 KEZ38050.1 - 5.6e-20 71.7 0.1 7.1e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator SBBP PF06739.11 KEZ38050.1 - 0.018 15.0 0.2 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 Beta-propeller repeat Glycos_transf_1 PF00534.20 KEZ38051.1 - 2.2e-35 121.7 0.0 2.9e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ38051.1 - 3.3e-30 105.3 3.4 3.9e-29 101.8 0.6 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEZ38051.1 - 2.4e-27 96.0 0.1 5.6e-27 94.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ38051.1 - 3e-25 89.5 5.5 3e-25 89.5 5.5 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ38051.1 - 5e-08 33.2 0.0 2.2e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KEZ38051.1 - 2.3e-05 24.2 1.7 0.0023 17.7 1.7 2.3 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 KEZ38051.1 - 0.026 14.5 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like Methyltransf_25 PF13649.6 KEZ38052.1 - 0.15 12.8 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.21 KEZ38053.1 - 2.7e-66 223.8 0.0 3e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BMC PF00936.19 KEZ38053.1 - 0.083 12.9 0.2 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 BMC domain US2 PF02476.15 KEZ38054.1 - 0.056 14.1 0.5 0.1 13.3 0.5 1.4 1 0 0 1 1 1 0 US2 family HTH_3 PF01381.22 KEZ38055.1 - 9.1e-14 51.3 0.6 1.4e-13 50.7 0.6 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ38055.1 - 1.6e-12 47.6 0.2 4.1e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ38055.1 - 1.3e-08 34.7 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ38055.1 - 0.00026 20.8 0.7 0.0048 16.7 0.7 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ38055.1 - 0.0034 17.8 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_35 PF13693.6 KEZ38055.1 - 0.022 14.8 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 KEZ38055.1 - 0.045 13.7 0.8 0.088 12.8 0.3 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_6 PF01418.17 KEZ38055.1 - 0.068 13.2 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Rrf2 PF02082.20 KEZ38055.1 - 0.11 12.8 0.2 0.55 10.6 0.0 2.1 1 1 1 2 2 2 0 Transcriptional regulator YdaS_antitoxin PF15943.5 KEZ38055.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TetR_N PF00440.23 KEZ38055.1 - 0.27 11.0 1.8 8.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family Sigma70_r4 PF04545.16 KEZ38055.1 - 0.32 10.5 2.1 24 4.5 0.0 3.1 3 0 0 3 3 3 0 Sigma-70, region 4 DUF349 PF03993.12 KEZ38056.1 - 2e-48 162.6 41.9 4.5e-22 78.1 6.5 4.0 4 0 0 4 4 4 3 Domain of Unknown Function (DUF349) DUF1090 PF06476.12 KEZ38056.1 - 0.086 13.0 0.4 0.086 13.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) SlyX PF04102.12 KEZ38056.1 - 5.4 7.7 9.2 49 4.6 0.3 4.8 5 0 0 5 5 5 0 SlyX BPD_transp_1 PF00528.22 KEZ38057.1 - 1.1e-12 48.0 19.1 1.1e-12 48.0 19.1 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3593 PF12159.8 KEZ38057.1 - 0.044 13.8 0.2 0.044 13.8 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3593) BPD_transp_1 PF00528.22 KEZ38058.1 - 1.6e-14 54.1 25.5 1.2e-13 51.2 25.5 2.1 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 KEZ38059.1 - 9.6e-20 71.8 0.1 1.3e-19 71.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KEZ38059.1 - 4.4e-16 59.5 0.0 5.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein TPALS PF18178.1 KEZ38059.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family ABC_tran PF00005.27 KEZ38060.1 - 1.3e-30 106.7 0.0 2.4e-30 105.8 0.0 1.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KEZ38060.1 - 3.8e-07 30.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 KEZ38060.1 - 1.2e-05 26.1 0.2 0.00013 22.8 0.2 2.8 1 1 0 1 1 1 1 MalK OB fold domain TOBE_2 PF08402.10 KEZ38060.1 - 3.8e-05 23.8 7.1 0.00027 21.0 4.0 3.1 2 1 0 2 2 2 1 TOBE domain CysA_C_terminal PF17850.1 KEZ38060.1 - 6.2e-05 23.5 0.7 6.2e-05 23.5 0.7 3.0 2 0 0 2 2 2 1 CysA C-terminal regulatory domain TOBE PF03459.17 KEZ38060.1 - 0.00016 21.9 3.0 0.00016 21.9 3.0 3.0 3 0 0 3 3 3 1 TOBE domain AAA_16 PF13191.6 KEZ38060.1 - 0.0003 21.2 0.2 0.00051 20.5 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KEZ38060.1 - 0.00033 20.3 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ38060.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ38060.1 - 0.096 13.2 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ38060.1 - 0.11 12.7 0.9 0.6 10.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KEZ38060.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KEZ38061.1 - 0.00062 19.8 0.0 0.0021 18.1 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ38061.1 - 0.0057 16.7 10.7 0.0058 16.7 0.1 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Dimer_Tnp_Tn5 PF02281.16 KEZ38061.1 - 0.036 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain TPR_12 PF13424.6 KEZ38061.1 - 0.038 14.3 15.1 0.056 13.8 1.4 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ38061.1 - 0.1 12.5 0.2 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ38061.1 - 0.13 12.4 0.4 0.75 10.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ38061.1 - 0.22 12.5 20.8 0.67 10.9 1.0 6.2 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ38061.1 - 0.37 11.3 0.1 0.37 11.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GCV_T PF01571.21 KEZ38062.1 - 2.8e-35 121.9 0.0 4.1e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KEZ38062.1 - 0.00074 19.4 0.1 0.0024 17.7 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain His_Phos_1 PF00300.22 KEZ38063.1 - 5.4e-33 114.3 0.9 2e-26 92.9 0.4 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PhoU PF01895.19 KEZ38064.1 - 3e-32 110.9 7.9 2.3e-17 63.2 4.7 2.1 2 0 0 2 2 2 2 PhoU domain HATPase_c PF02518.26 KEZ38065.1 - 7.5e-26 90.8 0.1 1.8e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ38065.1 - 4.2e-11 42.7 0.9 1.4e-10 41.1 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KEZ38065.1 - 2e-06 27.7 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KEZ38065.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KEZ38065.1 - 0.0009 19.2 0.0 0.003 17.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_7 PF12860.7 KEZ38065.1 - 0.0019 18.3 0.1 0.016 15.4 0.1 2.3 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 KEZ38065.1 - 0.086 12.9 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 PAS fold Trans_reg_C PF00486.28 KEZ38066.1 - 3.6e-27 94.2 0.3 1.5e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KEZ38066.1 - 5.5e-27 94.2 0.0 7.7e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Ppx-GppA PF02541.16 KEZ38067.1 - 3.1e-61 207.3 0.0 3.8e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family FtsA PF14450.6 KEZ38067.1 - 0.0028 18.1 0.0 0.33 11.4 0.0 2.4 2 0 0 2 2 2 2 Cell division protein FtsA AP_endonuc_2 PF01261.24 KEZ38068.1 - 1.9e-17 63.4 0.2 8.1e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel GDPD PF03009.17 KEZ38068.1 - 0.047 13.4 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Methyltransf_11 PF08241.12 KEZ38069.1 - 5.6e-20 71.8 0.0 9.7e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38069.1 - 8.3e-15 55.3 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38069.1 - 5.3e-07 29.6 0.0 7.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38069.1 - 3e-05 24.7 0.0 4.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38069.1 - 9.5e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KEZ38069.1 - 0.00015 21.6 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KEZ38069.1 - 0.048 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 KEZ38069.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.19 KEZ38069.1 - 0.24 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Acyl_transf_3 PF01757.22 KEZ38070.1 - 1.4e-22 80.3 29.5 2.5e-22 79.4 29.5 1.4 1 1 0 1 1 1 1 Acyltransferase family P5CR_dimer PF14748.6 KEZ38071.1 - 7.7e-36 122.5 0.6 1.3e-35 121.7 0.6 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KEZ38071.1 - 3.5e-16 59.6 3.2 3.5e-16 59.6 3.2 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KEZ38071.1 - 3.3e-06 26.8 1.9 1e-05 25.2 1.9 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KEZ38071.1 - 7.6e-05 23.0 1.2 0.00022 21.5 1.2 1.8 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KEZ38071.1 - 0.00022 21.4 1.3 0.00041 20.6 1.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KEZ38071.1 - 0.0012 19.0 0.4 0.0018 18.3 0.4 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KEZ38071.1 - 0.0037 17.5 0.9 0.0084 16.4 0.3 1.9 2 0 0 2 2 2 1 TrkA-N domain Rossmann-like PF10727.9 KEZ38071.1 - 0.016 15.1 5.8 0.031 14.2 5.8 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KEZ38071.1 - 0.035 14.1 1.9 0.65 10.0 1.9 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 KEZ38071.1 - 0.053 13.1 0.6 0.076 12.6 0.6 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF2007 PF09413.10 KEZ38071.1 - 0.084 13.1 0.3 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein SAM_adeno_trans PF01887.16 KEZ38072.1 - 5.4e-61 206.0 0.1 6.2e-61 205.8 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase Epimerase PF01370.21 KEZ38073.1 - 7.7e-19 68.1 0.0 1.6e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ38073.1 - 8.8e-09 35.2 0.0 8.2e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ38073.1 - 1.4e-05 24.3 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ38073.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Acyltransferase PF01553.21 KEZ38074.1 - 7e-16 58.1 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KEZ38074.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase HAD PF12710.7 KEZ38075.1 - 3.4e-28 99.3 0.5 5e-28 98.8 0.5 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ38075.1 - 1.4e-07 32.0 0.1 3.6e-07 30.7 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ38075.1 - 4.8e-07 29.8 0.0 1.2e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KEZ38075.1 - 0.024 14.2 0.0 0.059 12.9 0.0 1.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Sigma70_r2 PF04542.14 KEZ38076.1 - 1.4e-16 60.0 3.3 1.9e-16 59.6 1.6 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KEZ38076.1 - 1.8e-12 46.8 0.4 3.1e-12 46.0 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KEZ38076.1 - 3e-09 36.3 0.4 6.5e-09 35.2 0.4 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KEZ38076.1 - 3.4e-09 36.8 0.6 6.4e-09 36.0 0.6 1.4 1 1 0 1 1 1 1 ECF sigma factor DUF836 PF05768.14 KEZ38077.1 - 1.7e-17 63.6 0.0 1.9e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KEZ38077.1 - 0.004 17.3 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KEZ38077.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin domain Put_DNA-bind_N PF06971.13 KEZ38078.1 - 6.5e-20 70.9 0.0 1.3e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus CoA_binding PF02629.19 KEZ38078.1 - 3.8e-17 62.7 0.9 9.7e-17 61.5 0.6 1.8 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KEZ38078.1 - 0.0023 18.7 0.0 0.0035 18.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GlutR_N PF05201.15 KEZ38079.1 - 8.8e-44 148.8 0.0 1.4e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 KEZ38079.1 - 8.4e-30 103.6 0.0 1.8e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 KEZ38079.1 - 1.1e-19 70.7 0.1 2.2e-19 69.7 0.0 1.6 2 0 0 2 2 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain Sacchrp_dh_NADP PF03435.18 KEZ38079.1 - 0.0002 21.6 0.9 0.00042 20.6 0.9 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KEZ38079.1 - 0.00053 19.4 1.9 0.00096 18.5 1.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KEZ38079.1 - 0.00096 18.6 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KEZ38079.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KEZ38079.1 - 0.0035 17.7 0.6 0.0076 16.7 0.6 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 KEZ38079.1 - 0.0049 17.4 3.4 0.0093 16.5 1.5 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KEZ38079.1 - 0.0079 15.8 0.3 0.014 15.0 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Staph_opine_DH PF10100.9 KEZ38079.1 - 0.012 14.2 0.7 0.022 13.4 0.4 1.5 2 0 0 2 2 2 0 Staphylopine dehydrogenase CCDC85 PF10226.9 KEZ38079.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 CCDC85 family ApbA PF02558.16 KEZ38079.1 - 0.027 14.1 0.5 0.051 13.2 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 KEZ38079.1 - 0.032 14.3 0.8 0.08 13.0 0.8 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M17_N PF02789.17 KEZ38079.1 - 0.1 12.4 2.2 0.14 12.0 0.3 2.3 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain OCD_Mu_crystall PF02423.15 KEZ38079.1 - 0.17 10.8 4.1 0.38 9.6 1.5 2.1 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Porphobil_deam PF01379.20 KEZ38080.1 - 1.6e-69 233.5 0.1 2.3e-69 233.0 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KEZ38080.1 - 9.5e-15 54.7 0.3 2e-14 53.7 0.3 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain HEM4 PF02602.15 KEZ38081.1 - 2.6e-66 223.3 1.3 5.7e-66 222.2 1.3 1.5 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TP_methylase PF00590.20 KEZ38081.1 - 1.4e-26 93.8 10.8 5.6e-17 62.4 8.2 3.1 3 0 0 3 3 3 2 Tetrapyrrole (Corrin/Porphyrin) Methylases ALAD PF00490.21 KEZ38082.1 - 4.9e-133 443.2 0.1 5.6e-133 443.0 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase OMS28_porin PF03532.13 KEZ38082.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 OMS28 porin HMA PF00403.26 KEZ38083.1 - 1.5e-15 57.3 0.4 1.7e-15 57.2 0.4 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 KEZ38083.1 - 0.0031 17.8 1.2 0.053 13.9 0.3 2.2 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain E1-E2_ATPase PF00122.20 KEZ38084.1 - 6.8e-50 169.1 4.3 6.8e-50 169.1 4.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ38084.1 - 1.4e-43 149.6 11.4 1.4e-43 149.6 11.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEZ38084.1 - 6e-12 45.8 0.1 1.6e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 KEZ38084.1 - 3.6e-05 24.3 0.9 0.00017 22.0 0.9 2.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ38084.1 - 0.00051 19.9 0.7 0.00091 19.0 0.5 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2752 PF10825.8 KEZ38084.1 - 0.05 13.7 0.3 0.32 11.1 0.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) tRNA-synt_1g PF09334.11 KEZ38085.1 - 3.5e-99 332.2 0.0 1.1e-62 212.0 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEZ38085.1 - 5.3e-16 58.0 0.1 2.6e-07 29.3 0.0 3.0 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KEZ38085.1 - 1.8e-06 27.5 0.0 0.0096 15.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KEZ38085.1 - 2.5e-06 26.7 0.0 0.016 14.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Tn7_Tnp_TnsA_N PF08722.11 KEZ38088.1 - 0.0019 18.3 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 TnsA endonuclease N terminal DUF4228 PF14009.6 KEZ38088.1 - 0.0096 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) rve PF00665.26 KEZ38090.1 - 2.3e-13 50.4 0.0 4.5e-12 46.2 0.0 2.5 1 1 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 KEZ38090.1 - 4.8e-07 29.6 0.4 1.9e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Mu transposase, C-terminal rve_3 PF13683.6 KEZ38090.1 - 0.00019 21.2 0.0 0.0079 16.0 0.0 2.5 1 1 0 1 1 1 1 Integrase core domain HetR_C PF18460.1 KEZ38090.1 - 0.048 13.6 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain AAA_22 PF13401.6 KEZ38091.1 - 1.1e-22 80.7 0.0 3.4e-22 79.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KEZ38091.1 - 1.9e-11 43.7 0.0 3.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 KEZ38091.1 - 0.12 12.7 2.7 2.1 8.7 0.6 3.1 2 1 0 2 2 2 0 AAA ATPase domain Methyltransf_25 PF13649.6 KEZ38096.1 - 2.7e-20 72.9 0.0 4.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38096.1 - 1.1e-18 67.7 0.0 1.7e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38096.1 - 9.5e-15 54.8 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38096.1 - 1.2e-10 41.3 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38096.1 - 9.2e-10 39.2 0.0 1.9e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38096.1 - 0.00066 19.1 0.0 0.0014 18.1 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KEZ38096.1 - 0.0057 16.6 0.0 0.0087 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KEZ38096.1 - 0.0081 15.6 0.0 0.016 14.7 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 KEZ38096.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 KEZ38096.1 - 0.043 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KEZ38096.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 KEZ38096.1 - 0.07 12.6 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_33 PF10017.9 KEZ38096.1 - 0.13 11.4 0.0 2.3 7.3 0.0 2.4 2 1 1 3 3 3 0 Histidine-specific methyltransferase, SAM-dependent MerR_1 PF13411.6 KEZ38097.1 - 6.5e-13 48.6 0.0 7.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KEZ38097.1 - 5.2e-11 42.1 0.7 9.3e-11 41.3 0.1 1.6 2 0 0 2 2 2 1 MerR family regulatory protein AbiEi_4 PF13338.6 KEZ38097.1 - 0.0015 18.6 0.7 0.34 11.1 0.0 2.0 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin HTH_17 PF12728.7 KEZ38097.1 - 0.016 15.4 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain tRNA-synt_1d PF00750.19 KEZ38098.1 - 4.8e-44 150.7 0.1 2.5e-24 85.9 0.0 3.2 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KEZ38098.1 - 1.4e-16 60.7 0.0 4.1e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain DUF592 PF04574.13 KEZ38098.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF592) DUF4191 PF13829.6 KEZ38099.1 - 0.024 14.0 0.2 0.024 14.0 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) HemY_N PF07219.13 KEZ38099.1 - 0.13 12.5 0.5 0.13 12.5 0.5 1.1 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.6 KEZ38099.1 - 5.1 7.0 5.7 5.8 6.8 5.7 1.2 1 0 0 1 1 1 0 TMEM154 protein family Aminotran_3 PF00202.21 KEZ38100.1 - 1.1e-77 261.5 0.0 1.3e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III His_Phos_1 PF00300.22 KEZ38101.1 - 3.3e-35 121.5 0.3 4e-35 121.3 0.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Methyltransf_25 PF13649.6 KEZ38102.1 - 1.3e-05 25.8 0.1 2.9e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38102.1 - 0.00012 22.7 0.1 0.00055 20.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38102.1 - 0.00018 21.3 0.0 0.007 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38102.1 - 0.00034 21.3 0.1 0.0071 17.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38102.1 - 0.0017 18.2 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ38102.1 - 0.0022 17.5 0.0 0.033 13.7 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase OrfB_Zn_ribbon PF07282.11 KEZ38102.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 KEZ38102.1 - 0.16 11.6 1.0 0.38 10.4 1.0 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DNA_ligase_ZBD PF03119.16 KEZ38102.1 - 0.9 9.6 3.6 2.1 8.4 3.6 1.6 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain AhpC-TSA PF00578.21 KEZ38103.1 - 5.2e-18 65.2 0.0 7e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ38103.1 - 7.3e-16 58.2 0.0 9.8e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KEZ38103.1 - 1.6e-07 31.6 0.0 4.3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KEZ38103.1 - 2.2e-07 30.8 0.0 7.4e-07 29.1 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KEZ38103.1 - 0.00039 20.8 0.0 0.0012 19.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain GSHPx PF00255.19 KEZ38103.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase DsbD PF02683.15 KEZ38104.1 - 6e-45 153.8 13.6 3e-35 122.1 10.3 2.1 2 0 0 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 KEZ38104.1 - 3.1e-07 30.5 18.3 6.2e-07 29.5 18.3 1.6 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region ResB PF05140.14 KEZ38105.1 - 3.2e-126 422.0 0.0 8.1e-126 420.7 0.0 1.7 2 1 0 2 2 2 1 ResB-like family Cytochrom_C_asm PF01578.20 KEZ38106.1 - 4e-43 147.7 17.2 6.4e-43 147.0 17.2 1.3 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF4389 PF14333.6 KEZ38106.1 - 5.7 6.9 9.3 7.7 6.5 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) PLDc_N PF13396.6 KEZ38107.1 - 8.9e-10 38.3 5.3 1.4e-09 37.7 5.3 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal UbiD PF01977.16 KEZ38108.1 - 4.7e-155 516.4 0.1 5.8e-155 516.1 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiA PF01040.18 KEZ38109.1 - 6.8e-48 163.2 32.6 8.5e-48 162.9 32.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.19 KEZ38110.1 - 1.2e-14 54.4 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein DUF4229 PF14012.6 KEZ38111.1 - 9.5e-05 22.4 6.9 0.00012 22.1 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) DUF4133 PF13571.6 KEZ38111.1 - 0.0029 17.9 0.1 0.0041 17.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4133) RskA PF10099.9 KEZ38111.1 - 0.025 14.9 4.0 0.037 14.3 4.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA MASE2 PF05230.11 KEZ38111.1 - 0.028 14.5 2.1 0.038 14.0 2.1 1.2 1 0 0 1 1 1 0 MASE2 domain LapA_dom PF06305.11 KEZ38111.1 - 0.032 14.0 8.6 0.48 10.3 8.6 2.0 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3270 PF11674.8 KEZ38111.1 - 0.063 13.5 0.1 0.08 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) RseC_MucC PF04246.12 KEZ38111.1 - 0.066 13.2 0.3 0.081 12.9 0.3 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Radical_SAM PF04055.21 KEZ38112.1 - 2.3e-11 44.3 0.0 8e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily OAD_gamma PF04277.13 KEZ38113.1 - 0.35 11.5 3.0 0.88 10.2 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3007 PF11460.8 KEZ38113.1 - 0.5 10.7 1.9 0.66 10.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF4229 PF14012.6 KEZ38114.1 - 9.2e-07 28.9 9.1 1.2e-06 28.5 9.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) FA_desaturase PF00487.24 KEZ38114.1 - 0.15 11.9 1.8 0.17 11.7 1.8 1.1 1 0 0 1 1 1 0 Fatty acid desaturase LapA_dom PF06305.11 KEZ38114.1 - 2.3 8.1 7.7 25 4.8 7.7 2.1 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain VitK2_biosynth PF02621.14 KEZ38115.1 - 1.9e-73 247.3 0.0 2.1e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis HTH_31 PF13560.6 KEZ38116.1 - 2.1e-10 40.8 3.7 2.1e-10 40.8 3.7 2.4 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ38116.1 - 3.2e-05 23.9 0.1 8.6e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ38116.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ38116.1 - 0.028 14.3 0.2 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Response_reg PF00072.24 KEZ38117.1 - 9.2e-22 77.3 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain NIR_SIR PF01077.22 KEZ38118.1 - 1.5e-52 177.3 0.0 1.9e-37 128.2 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KEZ38118.1 - 1.3e-37 127.5 0.5 1.3e-18 66.6 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF1610 PF07754.11 KEZ38119.1 - 0.006 16.5 0.5 0.006 16.5 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1610) Lar_restr_allev PF14354.6 KEZ38119.1 - 0.06 13.7 0.5 0.078 13.4 0.5 1.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar Copper-fist PF00649.18 KEZ38119.1 - 0.063 12.8 0.4 0.099 12.2 0.4 1.3 1 0 0 1 1 1 0 Copper fist DNA binding domain DUF3268 PF11672.8 KEZ38119.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 KEZ38119.1 - 0.3 11.1 4.3 1 9.4 4.3 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 KEZ38119.1 - 1.3 9.4 6.6 29 5.0 6.6 2.3 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase PAPS_reduct PF01507.19 KEZ38120.1 - 2.2e-41 141.8 0.0 2.6e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TP_methylase PF00590.20 KEZ38121.1 - 1.6e-47 162.2 9.3 1.6e-47 162.2 9.3 2.6 3 0 0 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HEM4 PF02602.15 KEZ38121.1 - 4.7e-09 35.9 4.3 3.3e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Uroporphyrinogen-III synthase HemD Radical_SAM PF04055.21 KEZ38121.1 - 0.22 11.9 0.0 8.9 6.7 0.0 2.9 2 1 0 2 2 2 0 Radical SAM superfamily CbiX PF01903.17 KEZ38122.1 - 1e-23 83.7 0.0 5e-21 75.0 0.0 2.1 1 1 0 1 1 1 1 CbiX CbiK PF06180.11 KEZ38122.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.3 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) DUF3618 PF12277.8 KEZ38122.1 - 3 8.2 9.2 8.1 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Pyr_redox_2 PF07992.14 KEZ38123.1 - 2.6e-26 92.6 0.4 3.3e-26 92.2 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ38123.1 - 4.1e-18 65.7 0.1 2e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ38123.1 - 7e-13 49.0 0.7 1.9e-11 44.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ38123.1 - 6.4e-08 31.7 0.2 4.5e-05 22.3 0.3 3.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KEZ38123.1 - 4.9e-07 29.2 2.0 0.00023 20.4 0.1 3.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ38123.1 - 9.7e-07 28.9 0.9 8.3e-05 22.7 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEZ38123.1 - 9.5e-06 25.2 3.1 0.00017 21.1 0.6 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ38123.1 - 2.9e-05 23.3 0.9 0.41 9.7 0.2 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A Thi4 PF01946.17 KEZ38123.1 - 0.00012 21.4 0.5 0.004 16.4 0.1 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KEZ38123.1 - 0.0017 18.0 9.7 0.44 10.1 0.3 3.9 2 2 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEZ38123.1 - 0.0027 18.1 0.6 0.02 15.3 0.2 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KEZ38123.1 - 0.017 14.4 0.9 0.072 12.3 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 KEZ38123.1 - 0.022 13.9 0.8 0.12 11.5 0.0 2.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KEZ38123.1 - 0.056 12.7 0.2 0.41 9.9 0.0 2.3 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase DUF3933 PF13069.6 KEZ38123.1 - 0.07 13.0 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Lycopene_cycl PF05834.12 KEZ38123.1 - 0.21 10.6 2.5 3.5 6.6 0.1 2.9 3 1 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KEZ38123.1 - 0.68 9.2 5.1 0.81 8.9 0.0 2.8 2 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KEZ38123.1 - 0.95 9.4 4.5 8.8 6.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pkinase PF00069.25 KEZ38124.1 - 5e-37 127.7 0.0 6.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38124.1 - 1.5e-24 86.7 0.0 1.9e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ38124.1 - 8.6e-07 29.1 0.6 0.00074 19.5 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ38124.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ38124.1 - 0.036 13.7 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KEZ38124.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase X PF00739.19 KEZ38124.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Trans-activation protein X Radical_SAM PF04055.21 KEZ38126.1 - 9.3e-15 55.4 0.0 1.5e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily A_deaminase PF00962.22 KEZ38127.1 - 1.5e-68 231.6 0.0 1.7e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Ubie_methyltran PF01209.18 KEZ38128.1 - 3e-55 187.1 0.0 3.6e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KEZ38128.1 - 8.5e-15 55.2 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38128.1 - 6.1e-14 52.5 0.0 1.1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38128.1 - 2.7e-06 27.3 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38128.1 - 5.8e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38128.1 - 1.4e-05 25.7 0.0 2.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEZ38128.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase DLH PF01738.18 KEZ38129.1 - 4e-50 170.4 0.0 4.5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEZ38129.1 - 1.8e-05 24.4 0.1 0.0027 17.2 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEZ38129.1 - 7e-05 22.2 0.1 0.26 10.5 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KEZ38129.1 - 0.00041 20.3 0.1 0.41 10.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ38129.1 - 0.00051 20.7 8.8 0.015 15.9 8.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ38129.1 - 0.0041 16.8 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 KEZ38129.1 - 0.018 15.0 0.0 19 5.1 0.0 3.0 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KEZ38129.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.19 KEZ38130.1 - 5.5e-21 75.2 0.0 6.2e-18 65.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ38130.1 - 4.1e-12 46.4 3.8 2.2e-05 24.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ38130.1 - 3.5e-08 32.9 0.2 0.0024 17.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEZ38130.1 - 4.2e-08 32.7 0.2 2.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KEZ38130.1 - 1.4e-07 30.8 0.0 0.00046 19.2 0.1 3.0 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KEZ38130.1 - 1.2e-06 28.6 0.7 2.5e-06 27.6 0.2 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ38130.1 - 2e-06 27.3 0.2 6.6e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ38130.1 - 2.5e-06 26.9 0.1 4.9e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ38130.1 - 1.3e-05 24.7 0.1 2.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ38130.1 - 2.1e-05 23.8 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KEZ38130.1 - 6.2e-05 21.9 0.1 8.6e-05 21.4 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ38130.1 - 0.0027 17.0 0.0 0.0039 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEZ38130.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KEZ38130.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Oxidored_q4 PF00507.19 KEZ38131.1 - 3.7e-32 110.4 0.2 5.2e-32 109.9 0.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 PEP-CTERM PF07589.11 KEZ38131.1 - 2.3 8.5 5.2 3.5 7.9 0.1 2.6 2 0 0 2 2 2 0 PEP-CTERM motif Oxidored_q6 PF01058.22 KEZ38132.1 - 1.9e-23 82.8 0.1 2.6e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.19 KEZ38133.1 - 5.2e-45 153.0 0.0 6.8e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_49kDa PF00346.19 KEZ38134.1 - 2.3e-109 364.7 0.0 3.2e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KEZ38134.1 - 0.24 10.2 0.0 0.46 9.3 0.0 1.4 2 0 0 2 2 2 0 Nickel-dependent hydrogenase 2Fe-2S_thioredx PF01257.19 KEZ38135.1 - 1.9e-49 167.3 0.0 2.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_51K PF01512.17 KEZ38136.1 - 1.7e-46 157.8 0.0 2.4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KEZ38136.1 - 1.9e-31 107.9 0.1 3.3e-31 107.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KEZ38136.1 - 4e-10 39.4 0.1 8.5e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 SLBB domain Molybdopterin PF00384.22 KEZ38137.1 - 6e-19 68.3 0.0 1.5e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KEZ38137.1 - 2.6e-18 65.8 0.1 8.9e-18 64.1 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KEZ38137.1 - 2.2e-13 49.5 0.1 4.7e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molydop_binding PF01568.21 KEZ38137.1 - 2.1e-08 34.1 0.2 4.4e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KEZ38137.1 - 1.4e-07 31.4 1.8 1.5e-07 31.3 0.2 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2 PF00111.27 KEZ38137.1 - 7.5e-07 29.0 0.2 7.5e-07 29.0 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PhzC-PhzF PF02567.16 KEZ38137.1 - 0.1 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein NADHdh PF00146.21 KEZ38138.1 - 5.1e-123 410.1 16.3 6.3e-123 409.8 16.3 1.1 1 0 0 1 1 1 1 NADH dehydrogenase DUF4574 PF15141.6 KEZ38138.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 MAP17 PF15807.5 KEZ38138.1 - 0.13 12.5 7.9 0.3 11.3 2.2 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Fer4 PF00037.27 KEZ38139.1 - 2.4e-16 58.8 10.9 1.1e-08 34.5 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ38139.1 - 3e-11 43.7 6.3 6.2e-11 42.7 6.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ38139.1 - 5.3e-11 43.3 2.4 4.1e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KEZ38139.1 - 6.8e-11 42.1 15.9 2.6e-08 33.9 8.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ38139.1 - 5.2e-10 39.0 11.6 7e-05 22.7 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ38139.1 - 7.5e-10 38.3 10.8 3.8e-05 23.5 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KEZ38139.1 - 2.9e-09 36.9 3.5 0.00013 22.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ38139.1 - 9.8e-09 35.2 17.8 2.3e-07 30.9 8.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ38139.1 - 1.8e-08 34.7 0.8 0.0039 17.6 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ38139.1 - 1.5e-07 31.8 3.3 0.0053 17.3 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KEZ38139.1 - 1.4e-06 28.3 7.4 0.0095 16.4 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KEZ38139.1 - 3.6e-05 24.4 16.1 0.0027 18.5 3.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KEZ38139.1 - 4e-05 24.4 2.0 0.1 13.4 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KEZ38139.1 - 9.9e-05 22.5 2.0 0.36 11.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KEZ38139.1 - 0.00043 20.8 7.9 0.12 13.0 1.5 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KEZ38139.1 - 0.11 13.2 10.5 0.2 12.4 0.1 3.0 2 1 1 3 3 3 0 4Fe-4S single cluster domain DUF3454 PF11936.8 KEZ38139.1 - 0.85 10.1 3.4 0.52 10.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) Oxidored_q3 PF00499.20 KEZ38140.1 - 3.8e-34 117.5 18.4 4.9e-34 117.1 18.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4040 PF13244.6 KEZ38140.1 - 0.017 15.2 16.2 0.017 15.2 16.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Bd3614_N PF14442.6 KEZ38140.1 - 0.041 14.2 0.1 0.092 13.1 0.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Otopetrin PF03189.13 KEZ38140.1 - 6.6 5.4 6.5 9 5.0 6.5 1.1 1 0 0 1 1 1 0 Otopetrin Oxidored_q2 PF00420.24 KEZ38141.1 - 6.6e-24 83.6 11.1 8e-24 83.3 11.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ATP1G1_PLM_MAT8 PF02038.16 KEZ38141.1 - 0.53 9.8 3.1 7.1 6.2 0.2 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Proton_antipo_M PF00361.20 KEZ38142.1 - 9.7e-80 267.9 12.5 1.8e-79 267.0 12.5 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 KEZ38142.1 - 3.1e-25 88.0 1.3 1.3e-24 86.0 0.5 2.6 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q5_N PF01059.17 KEZ38142.1 - 0.065 13.3 0.5 0.23 11.5 0.5 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 KEZ38143.1 - 3.6e-63 213.5 14.3 3.6e-63 213.5 14.3 1.5 2 0 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 KEZ38143.1 - 0.0031 17.6 0.4 0.0031 17.6 0.4 2.6 2 1 0 2 2 2 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 KEZ38144.1 - 1.2e-73 247.9 17.5 1.2e-73 247.9 17.5 1.8 2 1 0 2 2 2 1 Proton-conducting membrane transporter polyprenyl_synt PF00348.17 KEZ38145.1 - 3.2e-58 196.8 0.0 4.1e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TPP_enzyme_C PF02775.21 KEZ38147.1 - 2e-28 99.1 0.1 3.7e-28 98.2 0.0 1.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KEZ38148.1 - 2.7e-50 171.3 0.0 4.3e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KEZ38148.1 - 1.6e-25 90.2 0.0 2.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_N PF02776.18 KEZ38148.1 - 8.4e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PFOR_II PF17147.4 KEZ38148.1 - 0.00018 21.8 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF2520 PF10728.9 KEZ38149.1 - 6.2e-32 110.0 0.0 8.8e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) Rossmann-like PF10727.9 KEZ38149.1 - 4.3e-23 81.6 10.3 6e-23 81.1 8.6 2.0 2 0 0 2 2 2 1 Rossmann-like domain F420_oxidored PF03807.17 KEZ38149.1 - 3.9e-06 27.4 0.2 9.3e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KEZ38149.1 - 0.0087 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KEZ38149.1 - 0.041 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KEZ38149.1 - 0.048 13.8 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEZ38149.1 - 0.048 13.6 0.1 2 8.3 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_M48 PF01435.18 KEZ38150.1 - 4.9e-34 117.8 0.0 7.4e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KEZ38150.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 BSP PF04450.12 KEZ38150.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria DUF520 PF04461.13 KEZ38151.1 - 1.8e-61 207.0 2.3 2e-61 206.8 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) LPD7 PF18821.1 KEZ38151.1 - 0.069 13.3 1.0 0.77 9.9 0.1 2.1 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 NLE PF08154.12 KEZ38151.1 - 0.075 13.6 0.1 13 6.4 0.0 2.5 3 0 0 3 3 3 0 NLE (NUC135) domain Pribosyltran PF00156.27 KEZ38152.1 - 9.7e-12 44.7 0.3 1.3e-11 44.3 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ38152.1 - 0.0013 18.2 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.6 KEZ38152.1 - 0.0038 17.3 0.0 0.0051 16.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain GGACT PF06094.12 KEZ38153.1 - 9e-16 58.6 0.0 1.1e-15 58.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Bax1-I PF01027.20 KEZ38154.1 - 2.4 7.9 11.8 13 5.6 11.9 1.8 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF308 PF03729.13 KEZ38154.1 - 9.5 6.6 20.7 0.17 12.3 8.4 2.7 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) Glyco_hydro_25 PF01183.20 KEZ38155.1 - 6.5e-44 150.2 0.0 8.4e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 LGFP PF08310.11 KEZ38155.1 - 4.6e-25 87.9 17.7 7e-10 39.3 0.5 4.5 5 0 0 5 5 5 3 LGFP repeat Ribosomal_L33 PF00471.20 KEZ38156.1 - 1.9e-23 82.6 6.3 2.1e-23 82.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N_2 PF14803.6 KEZ38156.1 - 0.0045 16.9 2.4 0.022 14.7 0.6 2.2 2 0 0 2 2 2 1 Nudix N-terminal zf-ribbon_3 PF13248.6 KEZ38156.1 - 0.005 16.2 1.0 0.017 14.5 0.1 2.0 2 0 0 2 2 2 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KEZ38156.1 - 0.0087 15.6 2.3 0.023 14.2 2.3 1.7 1 1 0 1 1 1 1 TFIIB zinc-binding RNA_POL_M_15KD PF02150.16 KEZ38156.1 - 0.012 15.5 0.6 0.68 9.9 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 KEZ38156.1 - 0.013 15.2 2.3 0.14 11.8 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 KEZ38156.1 - 0.013 15.6 1.8 0.023 14.8 1.8 1.4 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KEZ38156.1 - 0.015 16.0 1.5 0.019 15.7 1.5 1.1 1 0 0 1 1 1 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KEZ38156.1 - 0.026 14.6 1.9 0.055 13.5 0.1 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HypA PF01155.19 KEZ38156.1 - 0.036 14.1 0.9 0.045 13.8 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 KEZ38156.1 - 0.041 14.0 4.4 0.072 13.3 4.4 1.5 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 KEZ38156.1 - 0.064 13.0 1.7 0.064 13.0 1.7 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KEZ38156.1 - 0.082 12.9 3.2 0.18 11.9 3.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF983 PF06170.12 KEZ38156.1 - 0.5 10.8 1.5 3.6 8.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) MaoC_dehydrat_N PF13452.6 KEZ38157.1 - 1.4e-27 96.4 0.0 1.6e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KEZ38157.1 - 0.0001 21.8 0.0 0.00035 20.1 0.0 1.8 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydratas PF01575.19 KEZ38158.1 - 1.5e-24 85.9 0.0 2e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KEZ38158.1 - 6.5e-06 26.3 0.0 7.8e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Aminotran_1_2 PF00155.21 KEZ38159.1 - 2.6e-75 253.9 0.0 3e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEZ38159.1 - 6.9e-06 25.3 0.0 5.1e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ38159.1 - 3.2e-05 23.4 0.0 5.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEZ38159.1 - 3.3e-05 22.6 0.0 5.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KEZ38159.1 - 0.0063 15.8 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SecE PF00584.20 KEZ38160.1 - 1.8e-16 59.8 4.6 2e-16 59.6 4.6 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NusG PF02357.19 KEZ38161.1 - 1.8e-24 86.0 0.1 3.8e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 KEZ38161.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 KOW motif Ribosomal_L11_N PF03946.14 KEZ38162.1 - 1.6e-32 111.1 0.7 3.4e-32 110.1 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KEZ38162.1 - 1.9e-26 92.3 1.4 3.2e-26 91.6 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L1 PF00687.21 KEZ38163.1 - 9.2e-51 172.5 0.0 1.1e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L10 PF00466.20 KEZ38164.1 - 3.2e-26 91.4 0.0 6.4e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L12 PF00542.19 KEZ38165.1 - 3.7e-28 97.7 7.2 3.7e-28 97.7 7.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KEZ38165.1 - 4.3e-18 64.7 7.3 4.3e-18 64.7 7.3 2.8 3 0 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain RNA_pol_Rpb2_6 PF00562.28 KEZ38167.1 - 1.6e-159 531.1 0.0 4.2e-159 529.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KEZ38167.1 - 2.6e-30 104.4 0.0 5e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KEZ38167.1 - 4.7e-28 98.1 0.0 7e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KEZ38167.1 - 2.9e-27 94.9 0.0 5.6e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 KEZ38167.1 - 4.5e-25 87.7 0.0 3e-24 85.0 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_1 PF04563.15 KEZ38167.1 - 5.2e-22 78.4 0.0 2.4e-21 76.2 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RnfC_N PF13375.6 KEZ38167.1 - 0.12 12.3 0.1 0.41 10.6 0.1 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain RNA_pol_Rpb1_1 PF04997.12 KEZ38168.1 - 2.8e-82 276.6 0.0 4.7e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KEZ38168.1 - 1.3e-66 224.8 1.0 3.6e-65 220.0 1.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEZ38168.1 - 6.6e-39 133.8 0.0 7.6e-28 97.8 0.0 2.6 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KEZ38168.1 - 4.3e-22 78.7 0.0 7.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEZ38168.1 - 1.9e-10 40.7 0.0 5.9e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 CDPS PF16715.5 KEZ38168.1 - 0.012 15.3 0.2 0.026 14.2 0.2 1.5 1 0 0 1 1 1 0 Cyclodipeptide synthase PseudoU_synth_2 PF00849.22 KEZ38169.1 - 1.2e-24 87.2 0.0 1.2e-23 84.0 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase APO_RNA-bind PF05634.11 KEZ38169.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 APO RNA-binding DUF2437 PF10370.9 KEZ38169.1 - 1 10.3 4.3 23 5.9 0.8 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF2437) UDG PF03167.19 KEZ38170.1 - 2e-22 79.9 0.0 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosom_S12_S23 PF00164.25 KEZ38171.1 - 8.1e-43 144.7 2.6 9.3e-43 144.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 KEZ38172.1 - 2.2e-59 199.4 0.2 2.4e-59 199.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GTP_EFTU PF00009.27 KEZ38173.1 - 8.3e-68 227.8 0.0 1.3e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KEZ38173.1 - 7.8e-50 167.7 0.0 1.3e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KEZ38173.1 - 5.2e-35 119.4 0.1 1e-34 118.4 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KEZ38173.1 - 3.2e-30 104.0 0.0 7.9e-30 102.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEZ38173.1 - 4.8e-15 55.7 0.8 1.4e-14 54.2 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KEZ38173.1 - 1.1e-09 38.2 0.1 2.3e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KEZ38173.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEZ38173.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 KEZ38174.1 - 8.3e-57 191.9 0.0 1.1e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEZ38174.1 - 1.4e-34 118.8 0.1 2.7e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEZ38174.1 - 3.8e-17 62.4 6.7 3.8e-17 62.4 6.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ38174.1 - 6.8e-06 26.2 0.1 1.7e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ38174.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 KEZ38174.1 - 0.053 13.1 0.2 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S10 PF00338.22 KEZ38175.1 - 7.4e-37 125.5 0.1 8.2e-37 125.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 KEZ38175.1 - 0.11 13.3 0.0 1 10.2 0.0 2.0 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Ribosomal_L3 PF00297.22 KEZ38176.1 - 1.2e-16 60.6 6.7 6.8e-15 54.9 3.8 2.9 2 1 1 3 3 3 2 Ribosomal protein L3 Ribosomal_L4 PF00573.22 KEZ38177.1 - 6.8e-60 202.1 0.1 7.9e-60 201.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 KEZ38178.1 - 1.3e-30 105.6 0.0 1.4e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L2_C PF03947.18 KEZ38179.1 - 2e-55 186.4 4.5 3.8e-55 185.5 4.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KEZ38179.1 - 9.7e-33 112.0 1.0 4e-32 110.0 0.7 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S19 PF00203.21 KEZ38180.1 - 2.3e-35 120.3 0.2 2.7e-35 120.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.19 KEZ38181.1 - 6.6e-34 116.2 0.0 8.2e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RNA_pol_inhib PF16857.5 KEZ38181.1 - 0.021 14.6 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase inhibitor Ribosomal_S3_C PF00189.20 KEZ38182.1 - 1.7e-36 124.6 0.6 1.7e-36 124.6 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KEZ38182.1 - 8.2e-18 64.0 1.9 1.5e-17 63.2 1.9 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KEZ38182.1 - 0.0012 18.6 0.5 0.003 17.4 0.5 1.6 1 0 0 1 1 1 1 KH domain Rubella_Capsid PF05750.11 KEZ38182.1 - 0.27 10.8 14.1 0.5 9.9 14.1 1.3 1 0 0 1 1 1 0 Rubella capsid protein Ribosomal_L16 PF00252.18 KEZ38183.1 - 1.9e-45 154.1 0.4 2.1e-45 153.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L29 PF00831.23 KEZ38184.1 - 2.1e-25 88.5 2.1 2.5e-25 88.2 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein CCDC85 PF10226.9 KEZ38184.1 - 0.013 15.2 0.4 0.014 15.1 0.4 1.1 1 0 0 1 1 1 0 CCDC85 family Ribosomal_S17 PF00366.20 KEZ38185.1 - 2e-29 101.5 1.2 2.4e-29 101.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 KEZ38186.1 - 2.8e-53 179.2 0.0 3.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ribosomal_L24 PF17136.4 KEZ38187.1 - 1.8e-27 95.5 0.1 1.8e-27 95.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KEZ38187.1 - 2.8e-07 30.3 2.2 2.9e-07 30.2 0.5 2.0 2 0 0 2 2 2 1 KOW motif eIF3g PF12353.8 KEZ38187.1 - 0.029 14.8 0.5 0.06 13.7 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_L5_C PF00673.21 KEZ38188.1 - 1.3e-39 134.2 0.0 2.1e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KEZ38188.1 - 1.4e-26 92.5 0.6 2.3e-26 91.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S14 PF00253.21 KEZ38189.1 - 7.1e-23 80.1 6.7 8.1e-23 79.9 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2797 PF10977.8 KEZ38189.1 - 0.022 14.6 0.4 0.028 14.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Ribosomal_S8 PF00410.19 KEZ38190.1 - 3.1e-49 166.2 0.0 3.4e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 KEZ38191.1 - 1.1e-37 128.5 3.3 1e-18 67.8 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L18p PF00861.22 KEZ38192.1 - 2.9e-48 163.0 4.1 3.3e-48 162.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S5_C PF03719.15 KEZ38193.1 - 4.1e-29 99.8 0.1 6.2e-29 99.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KEZ38193.1 - 5.6e-27 93.5 4.2 8.2e-27 93.0 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L30 PF00327.20 KEZ38194.1 - 4.4e-19 68.1 0.2 5e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 KEZ38195.1 - 5.6e-34 117.6 1.3 7.5e-34 117.2 1.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SecY PF00344.20 KEZ38196.1 - 2.3e-113 378.5 14.9 2.7e-113 378.3 14.9 1.1 1 0 0 1 1 1 1 SecY translocase ADK PF00406.22 KEZ38197.1 - 2.3e-55 186.8 0.0 2.7e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEZ38197.1 - 9.2e-24 84.4 0.0 1.5e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KEZ38197.1 - 2.8e-15 56.0 3.0 4.3e-15 55.4 3.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KEZ38197.1 - 0.0099 16.4 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF1451 PF07295.11 KEZ38197.1 - 0.014 15.4 0.2 0.023 14.7 0.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Cytidylate_kin PF02224.18 KEZ38197.1 - 0.026 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_33 PF13671.6 KEZ38197.1 - 0.034 14.3 0.1 0.12 12.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.12 KEZ38197.1 - 0.043 13.3 1.0 0.043 13.3 1.0 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding zf-IS66 PF13005.7 KEZ38197.1 - 0.062 13.7 1.3 20 5.7 1.1 2.5 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 AAA PF00004.29 KEZ38197.1 - 0.087 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 KEZ38197.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 KEZ38197.1 - 0.14 12.1 1.0 0.25 11.3 1.0 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 KEZ38197.1 - 0.22 11.2 6.2 1.3 8.8 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 KEZ38197.1 - 0.63 10.0 0.1 0.63 10.0 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M24 PF00557.24 KEZ38198.1 - 2.3e-43 148.3 0.1 2.7e-43 148.1 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 eIF-1a PF01176.19 KEZ38199.1 - 1.2e-28 98.7 0.1 1.3e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_S13 PF00416.22 KEZ38200.1 - 2e-31 109.0 3.6 8.7e-30 103.7 3.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 PDDEXK_7 PF04411.12 KEZ38200.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Ribosomal_S11 PF00411.19 KEZ38201.1 - 1.9e-48 163.5 0.9 2.7e-48 162.9 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 ELFV_dehydrog PF00208.21 KEZ38201.1 - 0.0041 16.9 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_S4 PF00163.19 KEZ38202.1 - 6.4e-30 103.9 2.0 1.5e-29 102.7 2.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KEZ38202.1 - 1.1e-18 66.6 0.3 1.9e-18 65.9 0.3 1.4 1 0 0 1 1 1 1 S4 domain GDA1_CD39 PF01150.17 KEZ38202.1 - 0.051 12.2 0.0 0.065 11.9 0.0 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family S4_2 PF13275.6 KEZ38202.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain RNA_pol_A_CTD PF03118.15 KEZ38203.1 - 1.3e-26 92.1 0.0 2.2e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 KEZ38203.1 - 6.9e-24 84.4 0.0 1.2e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEZ38203.1 - 6.1e-18 64.0 0.0 9.9e-18 63.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HHH_5 PF14520.6 KEZ38203.1 - 0.013 16.1 0.2 0.67 10.6 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain Ribosomal_L17 PF01196.19 KEZ38204.1 - 2e-36 124.8 0.1 3.2e-36 124.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 YqgC PF17430.2 KEZ38204.1 - 0.049 13.7 0.1 0.093 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized YqgC-like PseudoU_synth_1 PF01416.20 KEZ38205.1 - 6.1e-32 110.3 0.0 1.7e-25 89.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ribosomal_L13 PF00572.18 KEZ38207.1 - 5.5e-54 181.7 0.0 6.3e-54 181.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 KEZ38208.1 - 3e-43 147.2 0.5 3.5e-43 147.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PGM_PMM_I PF02878.16 KEZ38209.1 - 1.8e-37 128.1 0.0 6.3e-37 126.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KEZ38209.1 - 8.2e-35 119.4 0.2 1.7e-34 118.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEZ38209.1 - 6.2e-18 65.3 1.2 1.7e-17 63.9 0.9 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KEZ38209.1 - 3.7e-11 43.0 2.7 1.5e-10 41.1 2.7 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SIS PF01380.22 KEZ38210.1 - 9.8e-59 196.9 0.0 8.9e-33 112.9 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KEZ38210.1 - 8.8e-17 61.6 3.6 1.5e-16 60.8 1.6 2.5 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEZ38210.1 - 3.1e-11 43.3 0.0 1.9e-10 40.7 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain bact-PGI_C PF10432.9 KEZ38210.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain SWIM PF04434.17 KEZ38212.1 - 0.00077 19.1 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Unstab_antitox PF09720.10 KEZ38212.1 - 0.16 12.0 1.5 0.39 10.8 1.0 1.8 2 0 0 2 2 2 0 Putative addiction module component PadR PF03551.14 KEZ38213.1 - 1.8e-20 72.7 0.0 2.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_32 PF13565.6 KEZ38213.1 - 0.022 15.4 0.0 1.4 9.6 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain TrmB PF01978.19 KEZ38213.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF1495 PF07381.11 KEZ38213.1 - 0.1 12.4 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) FUR PF01475.19 KEZ38213.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family ACPS PF01648.20 KEZ38214.1 - 7.2e-13 48.7 0.0 8.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KEZ38214.1 - 0.0077 16.3 3.1 0.54 10.4 3.1 2.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain Carb_kinase PF01256.17 KEZ38215.1 - 3.4e-48 164.2 5.8 5.5e-48 163.6 5.8 1.3 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 KEZ38215.1 - 1.9e-33 115.7 1.0 3.7e-33 114.8 1.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF4719 PF15843.5 KEZ38215.1 - 0.41 10.7 2.0 1.2 9.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Ala_racemase_N PF01168.20 KEZ38216.1 - 4e-61 206.5 1.2 6.2e-61 205.8 1.2 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 KEZ38216.1 - 2e-38 131.0 0.2 4.3e-38 129.9 0.0 1.6 2 0 0 2 2 2 1 Alanine racemase, C-terminal domain Abhydrolase_6 PF12697.7 KEZ38218.1 - 1.2e-21 78.3 7.7 1.2e-21 78.3 7.7 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ38218.1 - 3.2e-20 72.9 0.0 1.5e-19 70.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ38218.1 - 7.8e-19 67.9 0.1 7.8e-18 64.6 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEZ38218.1 - 1.8e-07 31.6 0.0 3.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 KEZ38218.1 - 9.5e-07 28.9 0.0 4e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 KEZ38218.1 - 0.00032 20.2 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KEZ38218.1 - 0.00048 19.8 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KEZ38218.1 - 0.00069 19.5 0.0 1.7 8.4 0.0 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 KEZ38218.1 - 0.014 15.2 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 KEZ38218.1 - 0.028 14.2 0.0 0.081 12.6 0.0 1.8 3 0 0 3 3 3 0 PGAP1-like protein FSH1 PF03959.13 KEZ38218.1 - 0.035 13.8 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF900 PF05990.12 KEZ38218.1 - 0.11 12.0 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) UCR_Fe-S_N PF10399.9 KEZ38218.1 - 0.62 9.4 6.5 1.7 8.0 6.5 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TsaE PF02367.17 KEZ38219.1 - 1.9e-30 105.5 0.0 2.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEZ38219.1 - 0.00033 20.8 0.3 0.0052 16.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KEZ38219.1 - 0.0091 15.8 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KEZ38219.1 - 0.019 15.4 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEZ38219.1 - 0.023 14.6 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KEZ38219.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KEZ38219.1 - 0.048 13.2 0.2 0.088 12.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ38219.1 - 0.076 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KEZ38219.1 - 0.13 11.7 0.1 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 KEZ38219.1 - 0.23 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain cobW PF02492.19 KEZ38219.1 - 0.24 11.0 1.3 0.29 10.7 0.2 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M22 PF00814.25 KEZ38220.1 - 1.1e-24 87.5 0.4 1.1e-24 87.5 0.4 1.5 2 0 0 2 2 2 1 Glycoprotease family GATase PF00117.28 KEZ38220.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF4719 PF15843.5 KEZ38220.1 - 0.061 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Reductase_C PF14759.6 KEZ38220.1 - 0.12 13.0 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Reductase C-terminal Acetyltransf_1 PF00583.25 KEZ38221.1 - 1.1e-14 54.6 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ38221.1 - 2.6e-11 43.6 0.0 4.2e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ38221.1 - 3.9e-09 36.8 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ38221.1 - 6.1e-09 35.7 0.1 9.8e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEZ38221.1 - 0.00028 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KEZ38221.1 - 0.00049 20.8 0.1 0.00063 20.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ38221.1 - 0.0034 17.5 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KEZ38221.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KEZ38221.1 - 0.027 14.6 2.5 0.037 14.2 2.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Flavodoxin_2 PF02525.17 KEZ38222.1 - 5e-36 124.3 0.0 6.2e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 KEZ38222.1 - 5.3e-10 39.3 0.0 2.3e-09 37.2 0.0 1.7 1 1 1 2 2 2 1 NADPH-dependent FMN reductase MarR_2 PF12802.7 KEZ38223.1 - 2.3e-10 40.2 2.5 3.4e-10 39.6 1.4 2.0 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KEZ38223.1 - 5.7e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KEZ38223.1 - 7.3e-08 32.8 0.1 1.4e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KEZ38223.1 - 0.00054 19.7 0.4 0.0021 17.8 0.1 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain TrmB PF01978.19 KEZ38223.1 - 0.0092 15.8 0.0 0.02 14.8 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 KEZ38223.1 - 0.015 15.6 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_CodY PF08222.11 KEZ38223.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ38223.1 - 0.087 12.8 0.4 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KEZ38223.1 - 0.16 12.2 2.1 0.25 11.5 0.3 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Cpn10 PF00166.21 KEZ38225.1 - 4.6e-34 116.4 0.3 5.2e-34 116.2 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 KEZ38226.1 - 4.2e-90 302.7 15.4 1e-89 301.4 15.4 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_CodY PF08222.11 KEZ38226.1 - 0.35 10.5 1.8 28 4.3 0.2 4.1 4 0 0 4 4 4 0 CodY helix-turn-helix domain Whib PF02467.16 KEZ38227.1 - 1.8e-23 82.9 2.0 2.3e-23 82.5 2.0 1.2 1 0 0 1 1 1 1 Transcription factor WhiB NUDIX_4 PF14815.6 KEZ38227.1 - 0.02 14.8 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain DUF5319 PF17252.2 KEZ38228.1 - 1.8e-45 154.1 0.0 2.1e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5319) IMPDH PF00478.25 KEZ38229.1 - 1.7e-154 514.0 3.9 1.9e-154 513.8 3.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KEZ38229.1 - 3.2e-23 81.9 1.7 1e-11 45.1 0.1 3.5 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 KEZ38229.1 - 7.3e-06 25.6 18.0 0.0033 16.9 0.8 3.1 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KEZ38229.1 - 0.0013 17.8 15.7 0.11 11.5 16.1 3.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEZ38229.1 - 0.0022 17.2 8.1 0.0022 17.2 8.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase ThiG PF05690.14 KEZ38229.1 - 0.02 14.2 4.9 0.011 15.0 2.2 2.1 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KEZ38229.1 - 0.034 13.6 2.3 0.13 11.7 2.3 1.9 1 1 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 KEZ38230.1 - 2.9e-33 115.3 1.6 8.8e-31 107.2 0.5 2.0 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEZ38230.1 - 3.1e-10 39.6 4.5 3.1e-10 39.6 4.5 2.6 3 0 0 3 3 3 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEZ38230.1 - 2.2e-05 23.8 2.0 3.6e-05 23.1 2.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KEZ38230.1 - 0.0001 21.7 5.0 0.011 15.1 1.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KEZ38230.1 - 0.00024 20.3 0.2 0.0034 16.5 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KEZ38230.1 - 0.59 9.3 1.9 7.2 5.7 0.4 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.15 KEZ38230.1 - 6.8 6.0 11.0 12 5.2 0.0 2.8 2 1 1 3 3 3 0 Nitronate monooxygenase DUF3577 PF12101.8 KEZ38231.1 - 0.039 13.7 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Peripla_BP_6 PF13458.6 KEZ38233.1 - 3.9e-32 112.2 4.4 6e-32 111.6 4.4 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KEZ38233.1 - 0.00033 19.9 0.0 0.00055 19.2 0.0 1.6 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KEZ38233.1 - 0.00091 18.3 0.2 0.53 9.2 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain ATP_bind_1 PF03029.17 KEZ38234.1 - 9.9e-29 100.8 2.1 4.9e-27 95.3 2.1 2.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KEZ38234.1 - 0.004 16.3 0.2 0.0052 15.9 0.2 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KEZ38234.1 - 0.011 15.4 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KEZ38234.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KEZ38234.1 - 0.057 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF742 PF05331.11 KEZ38235.1 - 2.3e-32 111.2 0.3 2.6e-32 111.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Robl_LC7 PF03259.17 KEZ38236.1 - 2.1e-22 78.7 0.4 2.9e-22 78.2 0.4 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain NIT PF08376.10 KEZ38237.1 - 2e-35 123.3 6.5 2e-35 123.3 6.5 2.4 2 0 0 2 2 2 1 Nitrate and nitrite sensing HATPase_c PF02518.26 KEZ38237.1 - 4.6e-08 33.6 0.0 8.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KEZ38237.1 - 3.3e-05 24.2 1.3 0.00012 22.4 1.3 2.1 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 KEZ38237.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMP_synt_C PF00958.22 KEZ38238.1 - 3.4e-43 145.6 0.0 7.2e-43 144.6 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KEZ38238.1 - 5e-39 134.0 0.0 7.3e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ38238.1 - 4.1e-10 39.8 0.0 1.5e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KEZ38238.1 - 5.2e-09 35.6 0.2 0.0001 21.5 0.2 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 KEZ38238.1 - 0.00049 19.0 0.1 0.0013 17.6 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KEZ38238.1 - 0.0015 18.1 0.0 0.037 13.5 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KEZ38238.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KEZ38238.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 KEZ38238.1 - 0.28 10.8 1.6 0.33 10.6 0.5 1.6 2 0 0 2 2 2 0 Asparagine synthase PALP PF00291.25 KEZ38239.1 - 1.5e-101 339.7 13.6 2.3e-101 339.1 13.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UvrD-helicase PF00580.21 KEZ38240.1 - 1.1e-73 248.5 0.0 5e-73 246.4 0.0 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEZ38240.1 - 1.3e-64 218.8 0.0 1.9e-63 215.0 0.0 2.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KEZ38240.1 - 3.1e-33 115.2 0.0 2.4e-32 112.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KEZ38240.1 - 6.1e-11 42.0 0.2 2.5e-10 40.0 0.2 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ38240.1 - 3.5e-07 30.1 0.4 9.3e-05 22.2 0.2 2.7 2 0 0 2 2 2 2 AAA domain Exonuc_V_gamma PF04257.14 KEZ38240.1 - 0.046 11.9 0.0 0.094 10.9 0.0 1.4 2 0 0 2 2 2 0 Exodeoxyribonuclease V, gamma subunit Carboxyl_trans PF01039.22 KEZ38241.1 - 1.8e-18 66.4 1.3 1.5e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain ECH_1 PF00378.20 KEZ38241.1 - 0.044 13.1 0.4 0.083 12.2 0.4 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 KEZ38242.1 - 3.1e-38 131.6 0.0 4.1e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38242.1 - 6.3e-23 81.4 0.0 7.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4190 PF13828.6 KEZ38242.1 - 1.2e-12 47.4 12.7 2.9e-12 46.1 12.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) APH PF01636.23 KEZ38242.1 - 7.2e-07 29.4 13.3 0.00083 19.4 0.2 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ38242.1 - 0.00059 19.2 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ38242.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.5 1 1 1 2 2 2 0 RIO1 family ORF_12_N PF18042.1 KEZ38242.1 - 0.06 13.8 0.3 0.13 12.7 0.3 1.5 1 0 0 1 1 1 0 ORF 12 gene product N-terminal Pkinase_fungal PF17667.1 KEZ38242.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ATP-grasp_2 PF08442.10 KEZ38243.1 - 1.3e-69 233.8 0.1 1.9e-69 233.3 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KEZ38243.1 - 2.4e-14 53.4 0.3 4.4e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KEZ38243.1 - 4.4e-09 36.1 1.1 4.4e-09 36.1 1.1 2.0 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KEZ38243.1 - 1.1e-06 28.6 0.1 2.1e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KEZ38243.1 - 0.00077 19.0 0.8 0.0021 17.6 0.2 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CoA_binding PF02629.19 KEZ38244.1 - 2.4e-26 92.3 6.4 3.2e-26 91.8 3.5 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KEZ38244.1 - 2.5e-14 53.4 0.6 5.2e-14 52.3 0.6 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KEZ38244.1 - 2.4e-12 46.8 1.1 3.9e-12 46.2 0.2 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KEZ38244.1 - 3.9e-07 30.6 0.4 1.2e-06 29.0 0.2 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KEZ38244.1 - 0.22 12.3 1.5 1.2 10.0 0.4 2.4 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold COX15-CtaA PF02628.15 KEZ38246.1 - 7.8 5.5 19.8 0.076 12.1 7.3 2.3 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein HTH_23 PF13384.6 KEZ38247.1 - 7.8e-06 25.5 6.0 0.0046 16.7 2.8 2.7 1 1 1 2 2 2 2 Homeodomain-like domain HTH_31 PF13560.6 KEZ38247.1 - 0.00011 22.4 0.3 0.00011 22.4 0.3 2.7 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ38247.1 - 0.00013 21.9 0.5 2.1 8.5 0.0 3.2 2 1 1 3 3 3 2 Helix-turn-helix Sigma70_r4_2 PF08281.12 KEZ38247.1 - 0.0039 16.8 0.1 0.12 12.1 0.1 2.3 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 KEZ38247.1 - 0.062 13.1 1.5 0.062 13.1 1.5 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Formyl_trans_N PF00551.19 KEZ38248.1 - 7.7e-49 165.9 0.0 8.9e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase AICARFT_IMPCHas PF01808.18 KEZ38249.1 - 1.3e-107 359.7 0.0 1.6e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KEZ38249.1 - 1.3e-20 73.3 0.0 2.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain PSD2 PF07624.11 KEZ38251.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) DUF3017 PF11222.8 KEZ38252.1 - 3.9e-21 75.1 20.4 6.8e-21 74.3 20.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3017) FAD_binding_3 PF01494.19 KEZ38253.1 - 2.1e-18 66.7 0.0 3.6e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ38253.1 - 1.3e-05 25.0 5.6 0.018 14.6 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEZ38253.1 - 0.00023 20.2 0.0 0.046 12.6 0.1 2.4 2 1 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 KEZ38253.1 - 0.00027 20.4 1.8 0.0004 19.9 1.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ38253.1 - 0.0022 17.3 0.3 0.0043 16.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ38253.1 - 0.024 13.3 0.4 0.033 12.9 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KEZ38253.1 - 0.033 14.4 0.2 0.11 12.8 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ38253.1 - 0.046 12.8 0.5 0.077 12.1 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KEZ38253.1 - 0.23 10.5 8.5 0.043 12.9 2.1 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Beta-lactamase PF00144.24 KEZ38254.1 - 7.1e-37 127.4 3.8 6.6e-36 124.2 3.8 1.9 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KEZ38254.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family 2_5_RNA_ligase2 PF13563.6 KEZ38255.1 - 1.6e-17 63.8 0.0 2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KEZ38255.1 - 1.1e-13 51.2 0.0 4.2e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase Peptidase_S11 PF00768.20 KEZ38257.1 - 4.5e-37 127.8 0.0 6e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KEZ38257.1 - 3.4e-08 33.3 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 KEZ38257.1 - 0.0061 15.3 0.0 0.0061 15.3 0.0 1.5 2 0 0 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF4381 PF14316.6 KEZ38257.1 - 0.0085 16.3 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF1180 PF06679.12 KEZ38257.1 - 0.074 13.5 0.4 0.074 13.5 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF1003 PF06210.11 KEZ38258.1 - 2.6e-36 123.9 0.2 3.6e-36 123.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) Acetyltransf_1 PF00583.25 KEZ38259.1 - 7.1e-15 55.3 0.0 8.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ38259.1 - 1.3e-06 28.7 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ38259.1 - 3.3e-06 27.0 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KEZ38259.1 - 4.2e-06 26.7 0.0 5.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ38259.1 - 0.00017 22.2 0.2 0.00024 21.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEZ38259.1 - 0.0035 17.5 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KEZ38259.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HicA_toxin PF07927.12 KEZ38261.1 - 1e-17 63.9 0.1 1.2e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, MGS PF02142.22 KEZ38261.1 - 0.1 12.8 0.1 13 6.1 0.0 2.0 1 1 1 2 2 2 0 MGS-like domain Resolvase PF00239.21 KEZ38263.1 - 1.5e-14 54.4 1.4 3e-14 53.3 0.3 1.9 2 0 0 2 2 2 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 KEZ38263.1 - 0.013 16.0 0.8 0.027 15.0 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Cys_rich_KTR PF14205.6 KEZ38263.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR T2SSF PF00482.23 KEZ38263.1 - 0.12 12.3 0.4 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F RVT_1 PF00078.27 KEZ38265.1 - 5e-14 52.3 0.0 6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2300 PF10062.9 KEZ38265.1 - 0.05 13.7 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) HTH_20 PF12840.7 KEZ38266.1 - 5.8e-10 39.1 0.0 9.2e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ38266.1 - 1.7e-07 31.0 0.0 9.3e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 KEZ38266.1 - 8.2e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF4423 PF14394.6 KEZ38266.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) MarR PF01047.22 KEZ38266.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 KEZ38266.1 - 0.004 17.1 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_47 PF16221.5 KEZ38266.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix HTH_Crp_2 PF13545.6 KEZ38266.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KEZ38266.1 - 0.045 13.3 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 KEZ38266.1 - 0.046 14.2 0.0 0.068 13.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.19 KEZ38266.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KEZ38266.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_DeoR PF08220.12 KEZ38266.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KEZ38266.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 HTH domain 3HCDH_N PF02737.18 KEZ38267.1 - 9.2e-117 387.3 2.1 1.4e-57 194.5 0.8 2.6 3 0 0 3 3 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ38267.1 - 4.4e-58 193.9 0.0 5.7e-29 100.6 0.0 3.0 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEZ38267.1 - 7.1e-11 42.5 2.8 0.00014 22.1 0.2 2.8 2 1 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ38267.1 - 4.9e-10 39.9 3.5 9.9e-05 22.9 0.1 2.8 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEZ38267.1 - 1.7e-06 27.5 6.1 0.0059 16.0 1.4 2.6 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEZ38267.1 - 1.1e-05 25.2 2.1 0.0026 17.4 0.2 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 KEZ38267.1 - 0.00077 19.5 4.9 0.32 11.0 0.2 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KEZ38267.1 - 0.004 16.7 1.4 0.77 9.3 0.1 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_Gly3P_dh_N PF01210.23 KEZ38267.1 - 0.0042 17.1 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KEZ38267.1 - 0.024 14.3 1.2 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KEZ38267.1 - 0.04 14.2 6.7 0.31 11.3 0.2 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KEZ38267.1 - 0.048 13.1 1.9 3 7.2 0.3 2.4 2 0 0 2 2 2 0 short chain dehydrogenase ThiF PF00899.21 KEZ38267.1 - 0.07 12.5 1.0 0.17 11.2 1.0 1.6 1 0 0 1 1 1 0 ThiF family DFP PF04127.15 KEZ38267.1 - 0.079 12.8 1.4 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein TetR_C_11 PF16859.5 KEZ38267.1 - 0.084 13.2 2.2 2.7 8.3 0.0 3.0 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain Arg_decarbox_C PF17944.1 KEZ38267.1 - 0.089 13.4 0.8 13 6.4 0.1 2.5 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension TrkA_N PF02254.18 KEZ38267.1 - 0.09 13.0 6.1 0.19 12.0 0.3 3.3 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.6 KEZ38267.1 - 0.1 13.1 4.3 0.95 9.9 0.2 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KEZ38267.1 - 0.45 11.1 4.8 0.45 11.1 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KEZ38268.1 - 1.7e-28 99.2 0.0 2.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ38268.1 - 6.8e-09 36.9 0.0 1.6e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ38268.1 - 4.2e-05 23.4 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KEZ38268.1 - 0.039 13.4 0.1 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Lipocalin_5 PF13924.6 KEZ38269.1 - 1.4e-40 138.4 0.0 1.6e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Abhydrolase_6 PF12697.7 KEZ38270.1 - 1.8e-20 74.5 6.3 2.3e-20 74.2 6.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ38270.1 - 1.9e-19 70.4 0.0 2.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ38270.1 - 2.7e-12 46.5 0.0 3.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEZ38270.1 - 0.0002 21.5 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KEZ38270.1 - 0.048 13.4 0.0 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 KEZ38270.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Na_H_Exchanger PF00999.21 KEZ38272.1 - 5.1e-50 170.4 43.6 6.3e-50 170.1 43.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Trp_halogenase PF04820.14 KEZ38274.1 - 1.9e-13 50.1 0.3 3.2e-07 29.5 0.5 2.9 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KEZ38274.1 - 9.9e-09 34.9 0.1 7.2e-08 32.1 0.0 2.4 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 KEZ38274.1 - 6.7e-08 32.5 2.1 3.8e-07 30.0 2.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEZ38274.1 - 1.5e-05 24.5 0.5 0.0041 16.5 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ38274.1 - 3.2e-05 23.2 0.4 7.4e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ38274.1 - 3.8e-05 23.1 0.0 0.00018 20.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ38274.1 - 5.9e-05 23.2 0.2 0.00023 21.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ38274.1 - 0.00016 22.2 0.0 0.0009 19.8 0.1 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ38274.1 - 0.00022 20.5 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KEZ38274.1 - 0.00053 19.2 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KEZ38274.1 - 0.00086 18.5 0.6 0.0058 15.7 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 KEZ38274.1 - 0.0013 17.5 0.1 0.0018 17.1 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 KEZ38274.1 - 0.0028 17.6 0.1 0.0045 16.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KEZ38274.1 - 0.0032 17.1 0.1 0.0051 16.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KEZ38274.1 - 0.0079 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KEZ38274.1 - 0.044 13.1 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEZ38274.1 - 0.094 11.9 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEZ38274.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GerE PF00196.19 KEZ38275.1 - 1.1e-14 53.7 0.0 2.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 KEZ38275.1 - 1.9e-06 28.2 0.0 3.9e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.6 KEZ38275.1 - 9.4e-05 22.6 28.7 0.00082 19.6 2.5 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ38275.1 - 0.00033 21.1 3.2 0.00033 21.1 3.2 3.9 4 2 0 4 4 4 1 AAA ATPase domain NB-ARC PF00931.22 KEZ38275.1 - 0.00049 19.4 0.0 0.0013 18.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain TPR_1 PF00515.28 KEZ38275.1 - 0.0089 15.8 1.3 0.023 14.5 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 KEZ38275.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 AAA_25 PF13481.6 KEZ38275.1 - 0.029 13.9 2.6 0.063 12.9 0.0 2.9 2 1 1 3 3 3 0 AAA domain Sigma70_r4_2 PF08281.12 KEZ38275.1 - 0.034 13.8 0.1 0.092 12.4 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 AAA_14 PF13173.6 KEZ38275.1 - 0.036 14.1 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.13 KEZ38275.1 - 0.17 12.6 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cmc1 PF08583.10 KEZ38275.1 - 0.51 10.4 1.6 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TPR_8 PF13181.6 KEZ38275.1 - 1.5 9.3 4.2 1.1 9.6 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ38275.1 - 5.7 7.3 11.4 1.6 9.1 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.21 KEZ38276.1 - 1.8e-81 274.2 0.4 2.8e-81 273.5 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 KEZ38276.1 - 4.5e-73 245.9 0.1 7.7e-72 241.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ38276.1 - 1.3e-36 125.2 0.1 4.1e-36 123.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEZ38276.1 - 6.3e-14 52.1 0.0 1.6e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KEZ38276.1 - 6.9e-12 45.8 0.0 1.5e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEZ38276.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KEZ38277.1 - 5.8e-27 93.4 0.3 1.2e-26 92.3 0.3 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KEZ38277.1 - 1e-25 89.7 0.4 1.8e-24 85.7 0.2 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ketoacyl-synt_C PF02801.22 KEZ38277.1 - 0.0035 17.4 0.3 3 7.9 0.1 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_N PF00195.19 KEZ38277.1 - 0.007 15.8 2.3 0.023 14.1 1.0 2.4 2 1 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain DUF3693 PF12472.8 KEZ38277.1 - 0.018 14.7 0.1 0.055 13.1 0.1 1.9 1 0 0 1 1 1 0 Phage related protein Thiolase_N PF00108.23 KEZ38277.1 - 0.058 12.7 0.7 0.12 11.8 0.1 1.8 2 1 0 2 2 2 0 Thiolase, N-terminal domain Peptidase_M22 PF00814.25 KEZ38277.1 - 0.12 12.1 0.8 3.3 7.3 0.3 2.1 2 0 0 2 2 2 0 Glycoprotease family CPSase_L_D2 PF02786.17 KEZ38278.1 - 5.3e-65 218.9 0.1 8.4e-65 218.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KEZ38278.1 - 4.6e-34 116.8 0.0 1.8e-33 114.9 0.0 2.1 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KEZ38278.1 - 1.7e-32 112.2 0.0 3.7e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ATP-grasp PF02222.22 KEZ38278.1 - 2.1e-10 40.4 0.0 3.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.22 KEZ38278.1 - 5.9e-09 35.6 0.0 1.7e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KEZ38278.1 - 1.7e-08 34.3 0.0 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KEZ38278.1 - 3.5e-06 27.1 0.0 7.8e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 KEZ38278.1 - 0.0037 16.7 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KEZ38278.1 - 0.012 15.2 0.0 0.042 13.5 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain CoA_binding_2 PF13380.6 KEZ38278.1 - 0.078 13.5 0.2 2.1 8.9 0.2 2.8 1 1 0 1 1 1 0 CoA binding domain ATP-grasp_2 PF08442.10 KEZ38278.1 - 0.2 11.2 0.2 11 5.5 0.0 2.6 2 1 1 3 3 3 0 ATP-grasp domain Carboxyl_trans PF01039.22 KEZ38279.1 - 9.1e-36 123.5 0.2 1.4e-35 122.9 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 KEZ38279.1 - 5.3e-11 41.5 0.1 6.9e-11 41.1 0.1 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region HTH_20 PF12840.7 KEZ38280.1 - 2e-12 47.0 0.2 4.6e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 KEZ38280.1 - 3.5e-09 36.4 0.0 5.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KEZ38280.1 - 1.5e-07 31.2 0.2 2.5e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 KEZ38280.1 - 5.8e-05 23.0 0.0 9.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 KEZ38280.1 - 6.2e-05 22.5 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KEZ38280.1 - 0.00036 20.4 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 KEZ38280.1 - 0.0004 20.3 0.1 0.00099 19.0 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 KEZ38280.1 - 0.00075 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_12 PF08461.10 KEZ38280.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease R winged-helix domain RepL PF05732.11 KEZ38280.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_IclR PF09339.10 KEZ38280.1 - 0.0076 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_28 PF13518.6 KEZ38280.1 - 0.011 15.9 0.4 0.027 14.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 KEZ38280.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator UPF0122 PF04297.14 KEZ38280.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TrmB PF01978.19 KEZ38280.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KEZ38280.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_36 PF13730.6 KEZ38280.1 - 0.18 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Crp PF00325.20 KEZ38280.1 - 0.19 11.4 0.7 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family GntR PF00392.21 KEZ38280.1 - 0.43 10.3 0.1 0.43 10.3 0.1 2.3 2 1 1 3 3 3 0 Bacterial regulatory proteins, gntR family PhnG PF06754.12 KEZ38281.1 - 0.048 13.6 0.5 0.1 12.5 0.2 1.6 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG HTH_20 PF12840.7 KEZ38283.1 - 2.6e-12 46.6 0.1 4.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 KEZ38283.1 - 8.1e-09 35.2 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KEZ38283.1 - 1.6e-07 31.1 0.1 3.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KEZ38283.1 - 2e-05 24.1 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AHSA1 PF08327.11 KEZ38283.1 - 6.6e-05 23.1 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein HTH_11 PF08279.12 KEZ38283.1 - 0.00013 21.8 0.0 0.00034 20.5 0.0 1.7 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.6 KEZ38283.1 - 0.00026 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 KEZ38283.1 - 0.00042 20.2 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 MarR family RepL PF05732.11 KEZ38283.1 - 0.0007 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_28 PF13518.6 KEZ38283.1 - 0.0028 17.8 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 KEZ38283.1 - 0.0042 16.8 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_12 PF08461.10 KEZ38283.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_IclR PF09339.10 KEZ38283.1 - 0.0095 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_29 PF13551.6 KEZ38283.1 - 0.02 14.9 0.9 0.025 14.6 0.1 1.6 2 0 0 2 2 1 0 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 KEZ38283.1 - 0.028 14.9 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Rrf2 PF02082.20 KEZ38283.1 - 0.029 14.7 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_36 PF13730.6 KEZ38283.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ38283.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Crp PF00325.20 KEZ38283.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_10 PF04967.12 KEZ38283.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain TrmB PF01978.19 KEZ38283.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 KEZ38283.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) GT87 PF09594.10 KEZ38284.1 - 2.6e-09 37.2 30.4 2.6e-09 37.2 30.4 3.5 2 1 1 3 3 3 1 Glycosyltransferase family 87 Oxidored_molyb PF00174.19 KEZ38285.1 - 5.4e-19 68.4 0.0 8.2e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Methyltransf_23 PF13489.6 KEZ38287.1 - 4.5e-08 33.1 0.0 3.6e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38287.1 - 3.6e-05 24.4 0.0 6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38287.1 - 0.00029 20.7 0.0 0.00074 19.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38287.1 - 0.00033 21.2 0.1 0.00087 19.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38287.1 - 0.00065 20.4 0.0 0.014 16.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KEZ38287.1 - 0.055 13.0 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 KEZ38287.1 - 0.094 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KEZ38287.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 KEZ38287.1 - 0.26 10.9 0.0 0.48 10.0 0.0 1.4 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DUF2064 PF09837.9 KEZ38288.1 - 1.4e-34 118.6 0.0 2.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) PEGSRP PF07623.11 KEZ38288.1 - 0.41 10.5 3.8 1.4 8.8 3.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Glycos_transf_2 PF00535.26 KEZ38289.1 - 9.4e-15 54.8 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ38289.1 - 0.00052 20.0 0.1 0.00099 19.1 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ38289.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Response_reg PF00072.24 KEZ38290.1 - 3.1e-30 104.6 0.0 4.9e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KEZ38290.1 - 7e-26 90.1 0.0 1.2e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 KEZ38290.1 - 2.5e-05 24.1 0.3 0.00015 21.6 0.3 2.3 1 1 0 1 1 1 1 MarR family HATPase_c PF02518.26 KEZ38291.1 - 1.9e-17 63.8 0.0 2.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ38291.1 - 1.4e-16 60.2 0.4 2.8e-16 59.3 0.4 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KEZ38291.1 - 0.00011 22.1 0.3 0.0003 20.8 0.3 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HAMP PF00672.25 KEZ38291.1 - 0.0016 18.8 0.9 0.075 13.4 0.1 2.7 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 KEZ38291.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 GHKL domain DUF1729 PF08354.10 KEZ38291.1 - 0.024 13.6 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) HATPase_c_3 PF13589.6 KEZ38291.1 - 0.053 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Epimerase PF01370.21 KEZ38292.1 - 5.2e-45 153.8 2.2 3e-44 151.3 2.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ38292.1 - 1.1e-37 130.3 0.0 6.3e-18 65.3 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ38292.1 - 1.3e-23 83.4 0.0 3e-19 69.1 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEZ38292.1 - 3.9e-14 53.0 0.8 8.6e-14 51.8 0.8 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEZ38292.1 - 7.3e-13 48.3 0.0 4.2e-09 36.0 0.1 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KEZ38292.1 - 6.8e-09 35.3 0.0 4.4e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KEZ38292.1 - 1.6e-08 34.2 4.5 2.9e-06 26.9 1.3 2.7 2 1 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.13 KEZ38292.1 - 3.7e-07 30.0 1.1 6e-07 29.3 1.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KEZ38292.1 - 1e-05 24.8 0.3 0.017 14.2 0.2 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.10 KEZ38292.1 - 0.0052 16.7 2.2 0.028 14.3 2.2 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KEZ38292.1 - 0.021 14.4 4.9 0.15 11.6 1.0 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.23 KEZ38292.1 - 0.049 13.7 1.9 0.091 12.8 1.6 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEZ38292.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEZ38292.1 - 0.13 12.5 0.3 0.27 11.5 0.3 1.5 1 1 0 1 1 1 0 TrkA-N domain YAcAr PF10686.9 KEZ38292.1 - 0.34 10.9 2.4 7.3 6.6 0.0 2.9 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family Pyr_redox_2 PF07992.14 KEZ38293.1 - 7.3e-52 176.4 1.0 9.1e-52 176.1 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ38293.1 - 2.7e-13 50.3 0.4 9.4e-08 32.5 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38293.1 - 5.9e-06 25.6 2.1 0.64 9.0 0.0 3.2 2 1 1 3 3 3 3 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KEZ38293.1 - 2.5e-05 24.4 0.2 0.0012 19.1 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ38293.1 - 3.5e-05 23.6 11.6 0.019 14.6 0.1 4.0 3 1 0 4 4 4 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ38293.1 - 0.00014 21.2 0.1 0.01 15.1 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 KEZ38293.1 - 0.0015 17.7 1.6 0.0037 16.4 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KEZ38293.1 - 0.0063 15.3 0.5 0.32 9.6 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein DUF1188 PF06690.11 KEZ38293.1 - 0.03 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Pyr_redox_3 PF13738.6 KEZ38293.1 - 0.05 12.9 1.6 4.4 6.5 0.1 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEZ38293.1 - 0.14 12.6 0.4 0.51 10.8 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KEZ38293.1 - 0.15 11.1 0.9 11 4.9 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEZ38293.1 - 0.54 10.2 8.2 5.2 7.0 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding DUF2613 PF11021.8 KEZ38294.1 - 0.0052 16.9 2.1 0.0052 16.9 2.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2613) DUF1344 PF07076.11 KEZ38294.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1344) Methyltransf_11 PF08241.12 KEZ38295.1 - 7e-22 77.9 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38295.1 - 3.3e-19 69.4 0.0 5.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38295.1 - 3e-13 49.6 0.0 4.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KEZ38295.1 - 3.4e-13 49.6 0.0 4.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38295.1 - 1.1e-09 38.9 0.0 1.5e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38295.1 - 5.4e-08 32.8 0.0 6.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KEZ38295.1 - 1.7e-05 23.6 0.0 2.8e-05 22.9 0.0 1.3 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 KEZ38295.1 - 0.00083 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KEZ38295.1 - 0.0075 17.3 0.0 0.013 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain OGFr_III PF04680.13 KEZ38295.1 - 0.022 15.3 1.3 0.022 15.3 1.3 2.0 2 0 0 2 2 1 0 Opioid growth factor receptor repeat Methyltransf_8 PF05148.15 KEZ38295.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase LAMTOR5 PF16672.5 KEZ38296.1 - 0.054 13.4 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 FHA PF00498.26 KEZ38297.1 - 8.9e-12 45.2 0.1 1.2e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEZ38297.1 - 2.6e-10 40.5 0.1 3.9e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rieske PF00355.26 KEZ38298.1 - 2.7e-14 52.9 0.0 3.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Peptidase_M1 PF01433.20 KEZ38300.1 - 2.9e-54 183.9 0.0 4.3e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KEZ38300.1 - 8.8e-43 147.0 2.9 8.8e-43 147.0 2.9 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KEZ38300.1 - 1.3e-06 28.7 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 KEZ38300.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 EthD PF07110.11 KEZ38300.1 - 0.84 10.8 4.0 6.5 8.0 0.0 3.8 3 2 1 4 4 4 0 EthD domain PMT_2 PF13231.6 KEZ38301.1 - 0.0038 17.4 17.2 0.0038 17.4 17.2 3.5 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 KEZ38301.1 - 1 8.9 13.7 2.5 7.6 13.7 1.7 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_tranf_2_3 PF13641.6 KEZ38302.1 - 6.3e-59 199.7 0.9 1.7e-58 198.2 0.9 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ38302.1 - 1.6e-20 73.9 13.0 1.9e-19 70.4 5.5 3.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEZ38302.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ38302.1 - 0.0005 19.6 0.1 0.0012 18.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEZ38304.1 - 1.1e-22 80.6 0.0 1.6e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 KEZ38304.1 - 2.9e-14 53.3 3.8 5.4e-14 52.4 3.8 1.4 1 0 0 1 1 1 1 GtrA-like protein Glyco_tranf_2_3 PF13641.6 KEZ38304.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FAD-oxidase_C PF02913.19 KEZ38306.1 - 2.9e-45 154.9 0.0 4.2e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ38306.1 - 7e-37 126.3 0.9 2.2e-36 124.7 0.9 1.9 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 KEZ38306.1 - 4.2e-07 30.3 1.4 8.1e-07 29.4 1.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ38306.1 - 2.1e-06 28.2 0.7 3.9e-06 27.3 0.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain CCG PF02754.16 KEZ38306.1 - 0.00025 21.2 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_7 PF12838.7 KEZ38306.1 - 0.012 16.2 1.1 0.031 14.8 1.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain DDE_Tnp_4 PF13359.6 KEZ38307.1 - 5.1e-27 94.5 0.0 6.5e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KEZ38307.1 - 2.8e-17 62.2 0.0 4.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ38307.1 - 4.7e-11 42.8 0.7 1.2e-10 41.4 0.7 1.7 1 1 0 1 1 1 1 Transposase DDE domain HTH_23 PF13384.6 KEZ38307.1 - 0.00098 18.9 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KEZ38307.1 - 0.024 14.7 0.1 0.091 12.9 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KEZ38307.1 - 0.028 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_39 PF14090.6 KEZ38307.1 - 0.042 13.6 0.0 0.61 9.9 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 KEZ38307.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.12 KEZ38307.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_22 PF13309.6 KEZ38307.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_17 PF12728.7 KEZ38307.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KEZ38307.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DDE_Tnp_4 PF13359.6 KEZ38308.1 - 1.5e-08 34.5 0.0 2.2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ38308.1 - 0.0046 16.6 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_38 PF13936.6 KEZ38309.1 - 6.1e-15 54.7 3.3 1.6e-14 53.4 2.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 KEZ38309.1 - 3.7e-08 33.8 0.3 3.7e-08 33.8 0.3 3.0 2 1 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 KEZ38309.1 - 0.00032 20.4 1.0 0.032 14.0 0.1 3.4 4 0 0 4 4 4 1 Homeodomain-like domain TetR_C_10 PF16295.5 KEZ38309.1 - 0.068 13.5 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4096 PF13340.6 KEZ38310.1 - 3.2e-10 40.1 0.8 1.9e-09 37.6 0.8 1.9 1 1 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 KEZ38311.1 - 0.00032 21.0 0.0 0.00034 20.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DUF433 PF04255.14 KEZ38313.1 - 0.00014 21.7 0.1 0.0016 18.3 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF433) HTH_23 PF13384.6 KEZ38313.1 - 0.0025 17.6 0.0 0.3 11.0 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KEZ38313.1 - 0.0057 16.2 0.0 2 8.0 0.0 3.0 3 0 0 3 3 3 2 Sigma-70, region 4 HTH_28 PF13518.6 KEZ38313.1 - 0.054 13.6 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 KEZ38314.1 - 1.5e-07 31.3 0.1 1.7e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 KEZ38314.1 - 1.6e-07 30.8 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KEZ38314.1 - 4.8e-07 29.5 0.0 7.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KEZ38314.1 - 5.1e-05 23.1 0.1 7.1e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 KEZ38314.1 - 6e-05 22.8 0.0 7.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KEZ38314.1 - 6.5e-05 22.9 0.1 9.1e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix MarR PF01047.22 KEZ38314.1 - 0.00044 20.1 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 KEZ38314.1 - 0.00081 19.1 0.3 0.0041 16.9 0.1 2.1 2 1 0 2 2 2 1 Homeodomain-like domain HTH_36 PF13730.6 KEZ38314.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ38314.1 - 0.0018 18.2 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KEZ38314.1 - 0.0022 18.2 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KEZ38314.1 - 0.0079 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 KEZ38314.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.6 1 1 1 2 2 2 0 Bacterial regulatory protein, arsR family LexA_DNA_bind PF01726.16 KEZ38314.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 LexA DNA binding domain FaeA PF04703.12 KEZ38314.1 - 0.018 15.4 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 FaeA-like protein HTH_38 PF13936.6 KEZ38314.1 - 0.021 14.6 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 KEZ38314.1 - 0.026 14.9 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator KorB PF08535.10 KEZ38314.1 - 0.047 13.7 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 KorB domain GntR PF00392.21 KEZ38314.1 - 0.065 12.9 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Replic_Relax PF13814.6 KEZ38314.1 - 0.067 13.2 0.0 0.086 12.9 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation HrcA_DNA-bdg PF03444.15 KEZ38314.1 - 0.071 12.8 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding RepB PF07506.11 KEZ38314.1 - 0.08 13.0 0.0 0.086 12.9 0.0 1.1 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF977 PF06163.11 KEZ38314.1 - 0.1 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_27 PF13463.6 KEZ38314.1 - 0.11 13.0 0.1 0.14 12.7 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Tnp_Tc3_1 PF11427.8 KEZ38314.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Tc3 transposase DUF4777 PF16007.5 KEZ38314.1 - 0.18 12.0 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) DDE_3 PF13358.6 KEZ38318.1 - 9.5e-23 80.6 0.0 1.8e-22 79.7 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease rve_2 PF13333.6 KEZ38318.1 - 0.0003 20.9 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KEZ38318.1 - 0.016 15.4 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 DDE domain Erf4 PF10256.9 KEZ38318.1 - 0.017 15.2 0.1 0.032 14.3 0.0 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family TFIIE_beta PF02186.15 KEZ38318.1 - 0.03 14.6 0.1 0.094 13.0 0.0 1.8 2 1 0 2 2 2 0 TFIIE beta subunit core domain AAA_19 PF13245.6 KEZ38319.1 - 7.6e-12 45.8 0.0 0.00015 22.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain UvrD_C_2 PF13538.6 KEZ38319.1 - 9.2e-08 31.8 0.0 3e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KEZ38319.1 - 1.6e-07 31.2 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KEZ38319.1 - 3.1e-07 30.4 0.0 0.0035 17.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KEZ38319.1 - 4.4e-06 26.6 1.4 0.097 12.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain UvrD_C PF13361.6 KEZ38319.1 - 0.00014 21.4 0.1 0.042 13.2 0.4 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KEZ38319.1 - 0.00017 21.1 0.0 0.19 11.2 0.0 2.6 3 0 0 3 3 3 2 PhoH-like protein DUF2075 PF09848.9 KEZ38319.1 - 0.003 16.8 0.2 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KEZ38319.1 - 0.0089 15.8 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ38319.1 - 0.011 16.1 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEZ38319.1 - 1.5 9.2 5.8 0.36 11.2 0.1 2.7 1 1 0 2 2 2 0 AAA ATPase domain DJ-1_PfpI PF01965.24 KEZ38320.1 - 1.2e-49 168.3 0.0 1.4e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KEZ38320.1 - 0.0075 16.1 0.0 0.018 14.8 0.0 1.6 1 1 1 2 2 2 1 Glutamine amidotransferase class-I Catalase_C PF18011.1 KEZ38320.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases Nitroreductase PF00881.24 KEZ38322.1 - 1e-14 55.0 2.2 2.4e-10 40.8 0.0 3.3 2 1 1 3 3 3 3 Nitroreductase family TM1586_NiRdase PF14512.6 KEZ38322.1 - 5.3e-05 22.9 0.0 0.22 11.1 0.0 3.1 3 0 0 3 3 3 3 Putative TM nitroreductase Pkinase PF00069.25 KEZ38323.1 - 6.9e-42 143.6 0.0 9.1e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38323.1 - 1.1e-24 87.1 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PD40 PF07676.12 KEZ38323.1 - 1.1e-23 82.6 15.1 5.6e-05 23.0 0.2 7.0 7 0 0 7 7 7 6 WD40-like Beta Propeller Repeat APH PF01636.23 KEZ38323.1 - 5.2e-07 29.8 3.7 0.0053 16.7 0.0 2.7 1 1 2 3 3 3 2 Phosphotransferase enzyme family DPPIV_N PF00930.21 KEZ38323.1 - 2.6e-05 23.1 0.0 0.13 11.0 0.0 2.5 2 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Kdo PF06293.14 KEZ38323.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ38323.1 - 0.0024 16.7 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEZ38323.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.5 2 0 0 2 2 2 0 RIO1 family TetR_C_16 PF17920.1 KEZ38323.1 - 0.14 12.4 0.4 0.31 11.3 0.4 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ABC_tran PF00005.27 KEZ38324.1 - 1.6e-30 106.4 0.0 3.7e-30 105.2 0.0 1.6 2 0 0 2 2 1 1 ABC transporter Yop-YscD_cpl PF16697.5 KEZ38324.1 - 2.1e-30 104.9 0.0 1.3e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KEZ38324.1 - 2.6e-29 101.4 0.9 2.8e-14 53.2 0.2 2.4 2 0 0 2 2 2 2 FHA domain ABC2_membrane PF01061.24 KEZ38324.1 - 4.7e-24 85.0 6.8 4.7e-24 85.0 6.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KEZ38324.1 - 7.8e-17 61.4 2.8 1.2e-16 60.8 2.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KEZ38324.1 - 3.1e-11 43.6 0.0 3.5e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ38324.1 - 1.8e-05 24.3 0.0 0.0082 15.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEZ38324.1 - 8.7e-05 22.5 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KEZ38324.1 - 0.00079 19.5 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KEZ38324.1 - 0.00088 19.0 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ38324.1 - 0.0022 18.3 0.2 0.024 14.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ38324.1 - 0.0046 17.4 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KEZ38324.1 - 0.009 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_30 PF13604.6 KEZ38324.1 - 0.0097 15.6 0.1 0.023 14.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KEZ38324.1 - 0.014 15.2 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KEZ38324.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MU2_FHA PF18221.1 KEZ38324.1 - 0.081 13.0 0.1 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Mutator 2 Fork head associated domain AAA_33 PF13671.6 KEZ38324.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain MIG-14_Wnt-bd PF06664.12 KEZ38324.1 - 0.46 9.6 2.0 9.7 5.3 0.0 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion ABC2_membrane_2 PF12679.7 KEZ38324.1 - 1.9 7.7 9.8 4.7 6.4 10.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3792 PF12670.7 KEZ38324.1 - 5 7.3 10.1 3.3 7.9 3.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF2993 PF11209.8 KEZ38326.1 - 6e-35 121.4 4.2 7.9e-35 121.0 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Poly_export PF02563.16 KEZ38326.1 - 0.0018 18.4 1.0 0.0032 17.7 0.3 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein adh_short PF00106.25 KEZ38327.1 - 2.3e-23 82.7 0.8 3.2e-23 82.2 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38327.1 - 2e-14 53.7 1.7 2.7e-14 53.3 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ38327.1 - 2e-05 24.6 1.9 3.3e-05 23.9 1.5 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ38327.1 - 0.024 13.8 0.0 0.042 13.0 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_holin_2_4 PF16082.5 KEZ38328.1 - 0.053 13.3 0.1 0.063 13.0 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like LapA_dom PF06305.11 KEZ38328.1 - 0.069 13.0 0.1 0.078 12.8 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FAD-oxidase_C PF02913.19 KEZ38329.1 - 6.4e-41 140.6 0.0 9.6e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ38329.1 - 3.9e-31 107.6 0.9 8.3e-31 106.6 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain TetR_N PF00440.23 KEZ38330.1 - 2.9e-09 36.6 0.0 6.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 KEZ38330.1 - 2.6e-05 24.9 1.4 6.2e-05 23.7 1.4 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 KEZ38330.1 - 0.00026 20.9 0.5 0.00049 20.0 0.5 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 KEZ38330.1 - 0.00043 20.3 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase LacI PF00356.21 KEZ38330.1 - 0.0033 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 KEZ38330.1 - 0.0099 15.6 0.4 0.026 14.3 0.2 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_8 PF02954.19 KEZ38330.1 - 0.012 15.4 1.1 0.042 13.6 0.9 2.0 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_AsnC-type PF13404.6 KEZ38330.1 - 0.025 14.4 1.0 0.065 13.1 1.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KEZ38330.1 - 0.089 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_AraC PF00165.23 KEZ38330.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family AbiEi_4 PF13338.6 KEZ38330.1 - 1.1 9.5 5.0 5.8 7.2 0.1 3.1 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin DAO PF01266.24 KEZ38331.1 - 4.9e-44 151.4 8.2 4.9e-44 151.4 8.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEZ38331.1 - 3e-16 59.4 0.0 6.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KEZ38331.1 - 0.0002 20.6 11.4 0.0014 17.8 11.4 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ38331.1 - 0.0049 16.3 2.3 0.011 15.1 1.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ38331.1 - 0.039 13.2 1.1 0.063 12.5 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38331.1 - 0.044 12.9 0.5 0.072 12.2 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KEZ38331.1 - 0.053 13.4 0.2 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KEZ38331.1 - 0.095 11.7 0.8 0.63 9.0 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ38331.1 - 0.27 11.5 3.0 1.4 9.2 1.9 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Acyl-CoA_dh_1 PF00441.24 KEZ38332.1 - 2.4e-20 73.3 5.2 4.2e-20 72.5 5.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ38332.1 - 2.4e-16 60.4 0.0 7.2e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ38333.1 - 8.5e-20 70.8 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KEZ38333.1 - 1.1e-19 71.1 0.1 1.7e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ38333.1 - 6.6e-15 55.7 1.1 9.1e-15 55.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DAO PF01266.24 KEZ38334.1 - 1.6e-50 172.7 8.4 2.9e-50 171.8 8.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEZ38334.1 - 1.4e-32 112.2 0.1 2.7e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KEZ38334.1 - 3.1e-06 26.5 13.2 4.3e-05 22.8 13.2 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ38334.1 - 8.6e-06 25.3 3.5 0.00032 20.2 1.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ38334.1 - 1.5e-05 24.5 1.4 0.035 13.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KEZ38334.1 - 0.00078 18.8 0.2 0.0016 17.7 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEZ38334.1 - 0.0026 17.6 0.1 0.0058 16.5 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KEZ38334.1 - 0.046 14.3 0.6 0.21 12.2 0.6 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38334.1 - 0.13 11.3 2.7 0.19 10.8 2.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KEZ38334.1 - 0.34 11.2 2.8 0.4 11.0 0.7 2.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ38335.1 - 2.8e-41 141.7 1.0 5.2e-41 140.8 1.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEZ38335.1 - 3.5e-21 75.5 0.1 7.1e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEZ38335.1 - 1.1e-15 58.0 3.1 4.3e-13 49.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ38335.1 - 2.3e-05 23.8 1.2 0.077 12.2 1.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ38335.1 - 3.5e-05 23.0 4.8 0.017 14.2 0.3 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.22 KEZ38335.1 - 6.2e-05 22.3 5.7 0.00071 18.8 2.5 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEZ38335.1 - 0.00064 18.9 1.2 0.00064 18.9 1.2 3.0 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 KEZ38335.1 - 0.00072 19.5 2.6 0.48 10.3 0.3 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEZ38335.1 - 0.00076 19.7 1.3 0.24 11.7 0.1 2.6 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 KEZ38335.1 - 0.0011 17.8 3.9 0.023 13.4 1.2 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KEZ38335.1 - 0.0021 17.4 1.6 0.0024 17.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KEZ38335.1 - 0.0081 15.6 0.4 0.0081 15.6 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ38335.1 - 0.014 15.6 3.8 3.4 8.0 0.2 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ38335.1 - 0.031 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KEZ38335.1 - 0.034 13.5 0.2 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KEZ38335.1 - 0.036 14.6 0.2 5.8 7.4 0.0 2.8 2 0 0 2 2 2 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KEZ38335.1 - 0.042 13.1 6.6 0.058 12.7 0.3 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 KEZ38335.1 - 0.054 14.1 0.8 15 6.3 0.1 3.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KEZ38335.1 - 0.11 12.9 2.5 7.1 7.1 0.2 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 KEZ38335.1 - 0.29 10.5 3.2 0.8 9.0 0.3 2.4 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 KEZ38335.1 - 0.34 10.1 6.5 0.048 12.9 0.8 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_2 PF03446.15 KEZ38336.1 - 1.4e-36 126.0 0.0 4.9e-36 124.3 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 KEZ38336.1 - 5.7e-19 68.6 0.9 1.2e-08 34.7 0.4 3.2 2 1 0 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 KEZ38336.1 - 5.3e-05 23.7 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KEZ38336.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEZ38336.1 - 0.00015 22.0 0.0 0.00055 20.2 0.0 1.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_11 PF14833.6 KEZ38336.1 - 0.00093 19.4 0.9 0.0028 17.9 0.6 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 KEZ38336.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ38336.1 - 0.0024 17.3 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KEZ38336.1 - 0.0052 17.6 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 KEZ38336.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YkuD PF03734.14 KEZ38337.1 - 0.003 18.0 0.3 0.0054 17.2 0.3 1.5 1 1 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF668 PF05003.12 KEZ38337.1 - 0.061 13.8 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF668) HHH PF00633.23 KEZ38337.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF853 PF05872.12 KEZ38339.1 - 2.2e-07 29.9 0.0 0.0001 21.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 KEZ38339.1 - 2.4e-07 31.1 0.0 3.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KEZ38339.1 - 4.1e-05 23.1 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 KEZ38339.1 - 0.00032 21.0 0.0 0.058 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ38339.1 - 0.0031 17.9 1.3 0.15 12.5 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KEZ38339.1 - 0.0049 15.8 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 KEZ38339.1 - 0.086 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEZ38339.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AbiEi_4 PF13338.6 KEZ38341.1 - 0.00037 20.6 0.5 0.0015 18.6 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin Methyltransf_23 PF13489.6 KEZ38342.1 - 1.5e-18 67.1 0.0 2.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38342.1 - 0.00011 22.9 0.0 0.00032 21.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain UDPGT PF00201.18 KEZ38343.1 - 1.8e-19 69.9 0.0 3.4e-19 69.0 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEZ38343.1 - 8.2e-08 32.4 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 KEZ38343.1 - 0.0044 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Abhydrolase_1 PF00561.20 KEZ38344.1 - 6.3e-21 75.2 0.1 1.7e-20 73.7 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ38344.1 - 1e-19 72.0 1.4 1e-19 72.0 1.4 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ38344.1 - 1.5e-18 67.0 0.2 5.3e-18 65.2 0.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEZ38344.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KEZ38344.1 - 0.032 12.9 0.0 0.11 11.2 0.0 1.8 1 1 0 2 2 2 0 Ndr family Lipase PF00151.19 KEZ38344.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Lipase PP-binding PF00550.25 KEZ38345.1 - 0.0035 17.7 0.4 0.0051 17.1 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site UxaE PF16257.5 KEZ38345.1 - 0.069 11.8 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 tagaturonate epimerase ketoacyl-synt PF00109.26 KEZ38346.1 - 1.5e-51 175.5 0.0 3.6e-40 138.2 0.0 3.1 3 1 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ38346.1 - 2.7e-34 117.7 0.4 5.1e-34 116.8 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KEZ38346.1 - 1.8e-17 63.5 0.1 4.2e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEZ38346.1 - 9.8e-16 58.1 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ACPS PF01648.20 KEZ38346.1 - 9.4e-10 38.6 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily KAsynt_C_assoc PF16197.5 KEZ38346.1 - 6.7e-08 33.0 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KEZ38346.1 - 0.0024 17.3 0.1 0.0048 16.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KEZ38347.1 - 1.9e-67 227.5 2.0 1.9e-67 227.5 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ38347.1 - 3e-34 118.5 1.7 5e-34 117.8 0.1 2.3 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KEZ38347.1 - 2.6e-33 114.5 1.0 8.2e-33 112.9 1.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEZ38347.1 - 7.5e-33 114.4 0.8 1.3e-32 113.5 0.8 1.4 1 0 0 1 1 1 1 Acyl transferase domain NMO PF03060.15 KEZ38347.1 - 2.9e-17 63.1 25.3 4.5e-08 32.9 2.4 4.9 4 1 0 4 4 4 3 Nitronate monooxygenase adh_short PF00106.25 KEZ38347.1 - 3.8e-12 46.1 10.6 7.6e-11 41.8 0.0 3.8 4 0 0 4 4 4 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38347.1 - 6.9e-09 35.6 0.1 6.9e-09 35.6 0.1 2.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KAsynt_C_assoc PF16197.5 KEZ38347.1 - 1.9e-07 31.6 0.0 4.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KEZ38347.1 - 9.1e-06 26.0 0.1 3.1e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KEZ38347.1 - 0.00057 19.3 0.6 0.00057 19.3 0.6 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain GerE PF00196.19 KEZ38348.1 - 5.6e-12 45.0 0.1 9.2e-12 44.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ38348.1 - 1.4e-05 24.7 0.1 2.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KEZ38348.1 - 0.013 15.3 0.2 0.044 13.6 0.2 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 KEZ38348.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 KEZ38348.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.6 3 0 0 3 3 3 0 Winged helix-turn helix GerE PF00196.19 KEZ38350.1 - 3e-14 52.3 0.0 5.5e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 KEZ38350.1 - 1.7e-06 28.5 3.6 3.6e-05 24.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain TPR_MalT PF17874.1 KEZ38350.1 - 7.1e-06 25.6 5.4 7.1e-06 25.6 5.4 3.1 3 1 0 3 3 3 1 MalT-like TPR region TPR_12 PF13424.6 KEZ38350.1 - 0.00067 19.9 6.3 0.00067 19.9 6.3 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ38350.1 - 0.014 15.5 8.6 0.15 12.2 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r4_2 PF08281.12 KEZ38350.1 - 0.015 14.9 0.1 0.065 12.9 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 TPR_1 PF00515.28 KEZ38350.1 - 0.018 14.9 1.7 0.049 13.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 KEZ38350.1 - 0.038 13.5 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_30 PF13556.6 KEZ38350.1 - 0.12 12.2 2.2 0.13 12.1 0.2 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DUF4193 PF13834.6 KEZ38351.1 - 6.8e-30 103.5 5.7 7.7e-30 103.3 5.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) Cpn10 PF00166.21 KEZ38352.1 - 1.4e-16 60.3 0.0 1.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit HATPase_c_2 PF13581.6 KEZ38358.1 - 2.2e-08 34.1 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KEZ38358.1 - 0.0008 19.9 0.0 0.0028 18.1 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LPG_synthase_TM PF03706.13 KEZ38359.1 - 1.7e-20 73.8 40.6 2.3e-20 73.3 40.6 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF3618 PF12277.8 KEZ38360.1 - 2.9e-13 49.8 4.9 4.7e-13 49.2 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) YqjK PF13997.6 KEZ38360.1 - 8.1 6.8 10.0 12 6.2 0.5 2.3 2 0 0 2 2 2 0 YqjK-like protein SCO1-SenC PF02630.14 KEZ38361.1 - 1.1e-28 99.8 0.0 1.5e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KEZ38361.1 - 2.3e-05 24.3 0.0 4.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ38361.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KEZ38361.1 - 0.0049 17.2 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like LIM_bind PF01803.16 KEZ38361.1 - 0.27 10.7 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 LIM-domain binding protein MauE PF07291.11 KEZ38362.1 - 8.6e-17 61.5 3.3 1.1e-16 61.1 3.3 1.2 1 0 0 1 1 1 1 Methylamine utilisation protein MauE DoxX PF07681.12 KEZ38362.1 - 4.8e-11 43.1 7.3 9.2e-11 42.2 7.3 1.4 1 0 0 1 1 1 1 DoxX DoxX_3 PF13781.6 KEZ38362.1 - 0.00072 20.1 3.6 0.00072 20.1 3.6 1.5 2 0 0 2 2 2 1 DoxX-like family DoxD PF04173.13 KEZ38362.1 - 0.004 17.1 5.4 0.12 12.3 2.6 2.7 2 1 0 3 3 3 2 TQO small subunit DoxD DoxX_2 PF13564.6 KEZ38362.1 - 2.5 8.3 11.8 0.088 12.9 6.0 1.5 2 0 0 2 2 2 0 DoxX-like family Thioredoxin_4 PF13462.6 KEZ38363.1 - 3.7e-34 118.3 0.0 5.3e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KEZ38363.1 - 2.4e-12 47.1 1.3 1.4e-10 41.3 1.3 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KEZ38363.1 - 0.0026 17.8 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KEZ38363.1 - 0.0052 17.2 0.0 0.0087 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain TraE PF05309.11 KEZ38363.1 - 0.099 12.0 0.2 3.2 7.1 0.1 2.1 2 0 0 2 2 2 0 TraE protein Chorion_2 PF03964.15 KEZ38363.1 - 0.27 12.1 5.5 23 5.9 3.2 2.5 2 0 0 2 2 2 0 Chorion family 2 RskA PF10099.9 KEZ38363.1 - 0.37 11.1 10.4 0.69 10.2 9.9 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA AhpC-TSA PF00578.21 KEZ38364.1 - 2e-38 131.1 0.0 2.3e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ38364.1 - 2e-25 89.2 0.0 2.5e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KEZ38364.1 - 4e-05 23.7 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 KEZ38364.1 - 0.0045 16.9 0.0 0.0059 16.5 0.0 1.4 1 1 0 1 1 1 1 SCO1/SenC DUF899 PF05988.12 KEZ38364.1 - 0.0067 16.0 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) GSHPx PF00255.19 KEZ38364.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase Arm-DNA-bind_4 PF14657.6 KEZ38366.1 - 1.2e-08 34.6 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 KEZ38366.1 - 3e-05 24.2 0.0 4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain ALF PF03752.13 KEZ38366.1 - 0.031 14.2 5.3 4.3 7.4 3.8 3.3 2 1 0 2 2 2 0 Short repeats of unknown function TPR_12 PF13424.6 KEZ38367.1 - 1.4e-31 108.6 6.1 1.3e-08 35.0 0.1 7.6 2 1 5 7 7 7 7 Tetratricopeptide repeat TIR_2 PF13676.6 KEZ38367.1 - 6e-27 94.6 0.1 1.8e-26 93.1 0.1 1.9 2 0 0 2 2 2 1 TIR domain TPR_10 PF13374.6 KEZ38367.1 - 1.3e-22 78.9 15.1 0.00036 20.3 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ38367.1 - 0.00052 20.4 0.2 0.0019 18.6 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KEZ38367.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TIR PF01582.20 KEZ38367.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 TIR domain ATPase_2 PF01637.18 KEZ38367.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABM PF03992.16 KEZ38368.1 - 6.9e-14 51.7 0.2 8e-14 51.5 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase RGI_lyase PF18370.1 KEZ38368.1 - 0.094 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain NAD_binding_2 PF03446.15 KEZ38369.1 - 7.1e-34 117.3 0.1 1.2e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEZ38369.1 - 8.3e-16 58.3 0.1 2.1e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ38369.1 - 6.2e-09 35.5 0.0 9.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ38369.1 - 1.4e-08 35.2 0.1 1.5e-07 31.9 0.1 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KEZ38369.1 - 0.00066 19.3 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KEZ38369.1 - 0.00092 19.2 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 KEZ38369.1 - 0.0037 16.9 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KEZ38369.1 - 0.0063 16.4 0.4 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ38369.1 - 0.028 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KEZ38369.1 - 0.07 13.4 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Asp_Glu_race PF01177.22 KEZ38371.1 - 6.3e-34 117.8 0.1 7.6e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Lactamase_B_2 PF12706.7 KEZ38372.1 - 2.5e-19 69.6 0.1 3.3e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEZ38372.1 - 2.1e-09 37.7 0.8 4.1e-09 36.7 0.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KEZ38372.1 - 0.0014 18.6 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RNase_PH PF01138.21 KEZ38373.1 - 2.3e-21 76.6 0.2 5.9e-21 75.3 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEZ38373.1 - 6.5e-09 35.7 0.2 1e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PALP PF00291.25 KEZ38375.1 - 2.1e-68 230.9 0.0 3e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiS PF02597.20 KEZ38376.1 - 4.5e-19 68.9 0.0 5.9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 KEZ38376.1 - 0.063 13.6 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Prok-JAB PF14464.6 KEZ38377.1 - 4.4e-25 87.8 0.3 4.9e-25 87.6 0.3 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KEZ38377.1 - 0.018 15.0 0.0 0.083 12.9 0.0 1.8 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2017 PF09438.10 KEZ38378.1 - 2e-49 167.9 6.7 2.2e-49 167.7 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2017) ClpS PF02617.17 KEZ38379.1 - 4e-23 81.0 0.0 4.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Molybdopterin PF00384.22 KEZ38380.1 - 3.4e-70 237.2 0.0 4e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KEZ38380.1 - 1.1e-32 112.4 0.0 2.3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KEZ38380.1 - 1.1e-06 28.6 0.2 6.5e-06 26.0 0.2 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Pyr_redox_2 PF07992.14 KEZ38381.1 - 1.5e-48 165.5 2.0 2.9e-48 164.6 1.3 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ38381.1 - 4.3e-15 56.0 0.8 9.5e-14 51.7 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KEZ38381.1 - 2.2e-14 53.1 0.0 4.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Fer2_BFD PF04324.15 KEZ38381.1 - 3e-10 40.3 3.6 5.8e-10 39.4 3.6 1.5 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain NAD_binding_8 PF13450.6 KEZ38381.1 - 0.004 17.3 0.3 0.51 10.6 1.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ38381.1 - 0.0085 15.3 0.0 13 4.8 0.0 3.6 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KEZ38381.1 - 0.026 13.3 0.4 1.6 7.4 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 KEZ38381.1 - 0.055 13.9 0.9 15 6.1 0.3 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 KEZ38381.1 - 0.17 11.2 7.5 0.17 11.2 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Reductase_C PF14759.6 KEZ38381.1 - 0.21 12.2 0.7 1.1 9.9 0.0 2.4 2 0 0 2 2 2 0 Reductase C-terminal AlaDh_PNT_C PF01262.21 KEZ38381.1 - 0.25 10.6 6.5 2.2 7.5 3.3 3.0 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KEZ38381.1 - 0.62 9.1 7.8 1.6 7.7 0.3 3.6 2 1 2 4 4 4 0 Lycopene cyclase protein GIDA PF01134.22 KEZ38381.1 - 0.83 8.7 6.9 0.6 9.1 0.5 3.0 3 1 0 4 4 4 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEZ38381.1 - 2.2 8.3 13.4 5.3 7.0 0.4 4.1 3 1 0 4 4 4 0 FAD-NAD(P)-binding NUDIX PF00293.28 KEZ38382.1 - 2.3e-16 60.0 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KEZ38382.1 - 0.00099 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NAPRTase_N PF17767.1 KEZ38383.1 - 4.4e-25 88.5 0.0 6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KEZ38383.1 - 1.9e-05 24.4 0.6 0.00024 20.8 0.6 2.3 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_C PF01729.19 KEZ38383.1 - 0.027 14.2 0.3 0.042 13.6 0.3 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain HTH_31 PF13560.6 KEZ38385.1 - 9.9e-16 57.9 0.6 3.6e-15 56.0 0.6 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KEZ38385.1 - 2.6e-11 43.4 0.0 5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KEZ38385.1 - 7.3e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KEZ38385.1 - 0.00031 20.6 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ38385.1 - 0.00045 20.0 0.1 0.00094 19.0 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KEZ38385.1 - 0.0032 17.3 0.2 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_26 PF13443.6 KEZ38385.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 KEZ38385.1 - 0.041 13.4 0.0 0.23 11.0 0.0 2.2 1 1 1 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 KEZ38385.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 KEZ38385.1 - 0.18 11.4 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Epimerase PF01370.21 KEZ38386.1 - 3e-42 144.7 0.0 3.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ38386.1 - 8.1e-37 127.3 0.0 2.3e-36 125.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEZ38386.1 - 5.2e-12 45.5 0.0 6.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEZ38386.1 - 3.1e-09 37.0 0.0 5.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ38386.1 - 2.8e-08 33.1 0.0 3.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ38386.1 - 3.6e-08 32.9 0.0 3.2e-05 23.2 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KEZ38386.1 - 1.5e-05 24.7 0.0 6.8e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KEZ38386.1 - 0.00033 19.9 0.1 0.0086 15.2 0.1 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KEZ38386.1 - 0.061 12.8 1.7 1.5 8.2 0.5 3.1 3 1 0 3 3 3 0 short chain dehydrogenase BPD_transp_2 PF02653.16 KEZ38388.1 - 6.3e-45 153.4 74.3 5.1e-24 84.9 34.0 2.2 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component DUF3948 PF13134.6 KEZ38388.1 - 8.7 6.1 10.9 2.3 8.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3948) ABC_tran PF00005.27 KEZ38389.1 - 1.5e-28 100.0 0.0 2e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ38389.1 - 5.3e-10 39.6 0.1 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 KEZ38389.1 - 4.1e-05 23.4 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 KEZ38389.1 - 8.4e-05 22.1 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ38389.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ38389.1 - 0.0053 17.3 0.1 0.0079 16.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ38389.1 - 0.053 13.2 0.0 0.3 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ38389.1 - 0.061 13.7 0.3 0.12 12.7 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ38389.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ38389.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KEZ38389.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 KEZ38389.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 KEZ38389.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ38390.1 - 6.3e-25 88.3 0.0 8.6e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ38390.1 - 4e-12 46.6 0.8 1.5e-06 28.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 KEZ38390.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_30 PF13604.6 KEZ38390.1 - 0.016 15.0 1.8 0.096 12.4 1.8 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEZ38390.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ38390.1 - 0.025 14.9 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KEZ38390.1 - 0.038 13.4 0.0 3.2 7.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ38390.1 - 0.1 12.9 0.3 0.22 11.9 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 KEZ38390.1 - 0.13 11.8 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KEZ38390.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ38390.1 - 0.18 12.3 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peripla_BP_6 PF13458.6 KEZ38391.1 - 2.4e-56 191.9 7.3 4e-56 191.1 7.3 1.3 1 1 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KEZ38391.1 - 9.5e-05 21.5 0.1 0.0091 15.0 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain HTH_Crp_2 PF13545.6 KEZ38392.1 - 0.00056 19.8 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 KEZ38392.1 - 0.0094 15.7 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain GntR PF00392.21 KEZ38392.1 - 0.033 13.8 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 KEZ38392.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KEZ38392.1 - 0.09 12.7 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 MarR family MarR PF01047.22 KEZ38392.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family Arginase PF00491.21 KEZ38394.1 - 8.8e-81 271.5 0.4 1e-80 271.3 0.4 1.0 1 0 0 1 1 1 1 Arginase family DUF2752 PF10825.8 KEZ38395.1 - 2e-18 66.2 4.1 2e-18 66.2 4.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2752) Collagen PF01391.18 KEZ38395.1 - 2.6e-05 23.9 15.2 4.2e-05 23.2 15.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3039 PF11238.8 KEZ38395.1 - 0.0053 16.5 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) SpoU_methylase PF00588.19 KEZ38396.1 - 1.4e-28 99.8 0.0 2.2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KEZ38396.1 - 0.038 14.3 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DEC-1_N PF04625.13 KEZ38396.1 - 1.5 7.8 7.7 2.5 7.0 7.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Amidohydro_1 PF01979.20 KEZ38397.1 - 2.6e-52 178.3 0.0 3.5e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ38397.1 - 2.3e-10 40.5 1.0 2.3e-10 40.5 1.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family HpcH_HpaI PF03328.14 KEZ38398.1 - 2.9e-08 33.1 0.2 7.1e-08 31.9 0.2 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Ribosomal_L12_N PF16320.5 KEZ38398.1 - 8.8 6.1 11.2 0.41 10.4 0.9 3.4 2 1 1 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Transthyretin PF00576.21 KEZ38399.1 - 2.5e-27 95.7 0.0 3.2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF234 PF03008.14 KEZ38400.1 - 0.11 12.9 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Allantoicase PF03561.15 KEZ38401.1 - 1.8e-85 284.2 0.0 6e-43 146.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat OHCU_decarbox PF09349.10 KEZ38401.1 - 1e-37 130.0 0.6 1.5e-37 129.5 0.6 1.2 1 0 0 1 1 1 1 OHCU decarboxylase GGDEF_2 PF17853.1 KEZ38401.1 - 0.07 13.4 3.5 0.34 11.2 0.4 2.8 2 0 0 2 2 2 0 GGDEF-like domain Amidohydro_1 PF01979.20 KEZ38402.1 - 3.6e-26 92.3 0.1 5.1e-25 88.5 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ38402.1 - 1.2e-08 34.9 11.8 1.7e-06 27.8 0.1 3.2 2 1 1 3 3 3 2 Amidohydrolase family Ald_Xan_dh_C2 PF02738.18 KEZ38403.1 - 4.9e-136 454.4 0.7 6.2e-136 454.1 0.7 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 KEZ38403.1 - 2e-27 95.7 0.2 4.3e-27 94.6 0.2 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KEZ38404.1 - 8.8e-27 92.9 0.2 1.6e-26 92.1 0.2 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2_3 PF13085.6 KEZ38404.1 - 0.00012 22.1 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 KEZ38404.1 - 0.00096 19.1 0.4 0.00096 19.1 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_5 PF00941.21 KEZ38405.1 - 2.6e-29 102.1 0.1 3.8e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KEZ38405.1 - 2.2e-06 27.8 1.8 1.6e-05 25.0 1.8 2.1 1 1 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Adenine_deam_C PF13382.6 KEZ38406.1 - 3.7e-34 117.5 0.0 7.7e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 KEZ38406.1 - 0.031 13.6 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase family Urease_gamma PF00547.18 KEZ38408.1 - 4.2e-44 148.9 0.1 4.8e-44 148.7 0.1 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 KEZ38409.1 - 1.3e-38 130.9 0.0 1.7e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_1 PF01979.20 KEZ38410.1 - 2.5e-67 227.6 0.6 3.3e-67 227.2 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KEZ38410.1 - 3.5e-52 175.8 0.3 5.9e-52 175.1 0.3 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 KEZ38410.1 - 6.8e-08 32.4 7.9 7.4e-07 29.0 3.2 2.4 1 1 1 2 2 2 2 Amidohydrolase family Molybdopterin_N PF18364.1 KEZ38410.1 - 0.078 13.0 1.5 0.31 11.1 0.4 2.4 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain UreF PF01730.16 KEZ38411.1 - 5.2e-20 72.4 3.8 7.9e-20 71.8 3.8 1.3 1 0 0 1 1 1 1 UreF UreD PF01774.17 KEZ38412.1 - 4.9e-30 105.0 0.0 6.4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Glyco_tranf_2_3 PF13641.6 KEZ38413.1 - 5.8e-19 68.9 0.1 8e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ38413.1 - 8.1e-18 64.8 0.0 2.1e-17 63.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ38413.1 - 5.9e-16 58.4 0.0 9.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KEZ38413.1 - 2.5e-07 30.8 1.9 2.5e-07 30.8 1.9 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 KEZ38413.1 - 0.039 14.5 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DNA_pol_B_palm PF14792.6 KEZ38413.1 - 0.22 11.7 0.0 0.66 10.2 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase beta palm TetR_N PF00440.23 KEZ38414.1 - 1e-16 60.4 1.0 2.7e-16 59.1 1.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF3463 PF11946.8 KEZ38415.1 - 5.6e-55 184.8 0.1 1e-54 184.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) Radical_SAM PF04055.21 KEZ38415.1 - 1.5e-17 64.5 0.0 2.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KEZ38415.1 - 7.4e-07 29.3 0.0 3e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KEZ38415.1 - 6.3e-06 26.5 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain 4HBT PF03061.22 KEZ38416.1 - 3.5e-14 52.9 1.5 6.7e-14 52.0 1.1 1.7 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 KEZ38416.1 - 5.2e-06 26.6 0.0 7.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KEZ38416.1 - 0.011 16.0 3.0 0.015 15.5 0.6 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily HxlR PF01638.17 KEZ38417.1 - 7.9e-22 76.9 0.0 9.2e-22 76.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 KEZ38417.1 - 0.0019 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 KEZ38417.1 - 0.016 15.2 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 Replication-relaxation HTH_CodY PF08222.11 KEZ38417.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_34 PF13601.6 KEZ38417.1 - 0.045 13.9 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain LYTB PF02401.18 KEZ38418.1 - 5.5e-81 271.7 0.0 6.9e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 LytB protein PNP_UDP_1 PF01048.20 KEZ38418.1 - 4.9e-15 55.4 5.1 2.6e-14 53.1 5.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily DUF2486 PF10667.9 KEZ38418.1 - 0.02 15.1 10.3 0.04 14.1 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) CoA_binding_2 PF13380.6 KEZ38418.1 - 0.9 10.1 5.7 4.8 7.7 0.2 3.2 3 0 0 3 3 3 0 CoA binding domain SQHop_cyclase_C PF13243.6 KEZ38419.1 - 9.6e-134 445.5 5.8 4.8e-94 315.0 0.1 4.3 4 0 0 4 4 4 4 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KEZ38419.1 - 3.6e-127 423.5 5.6 1.5e-117 391.9 0.4 4.6 4 1 1 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KEZ38419.1 - 8.1e-31 105.5 9.3 2.7e-10 39.8 0.1 6.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KEZ38419.1 - 1.9e-10 40.3 0.0 0.01 14.9 0.0 5.2 3 1 2 5 5 5 4 A-macroglobulin TED domain Mago-bind PF09282.10 KEZ38419.1 - 0.073 13.0 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 Mago binding polyprenyl_synt PF00348.17 KEZ38420.1 - 3.6e-52 177.0 0.0 4.4e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Amino_oxidase PF01593.24 KEZ38421.1 - 2.8e-37 129.1 1.1 3.8e-37 128.6 1.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ38421.1 - 1.2e-13 51.1 0.6 3.2e-13 49.7 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEZ38421.1 - 7e-10 38.8 1.0 9.9e-10 38.3 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ38421.1 - 5.2e-07 29.1 1.4 8.7e-07 28.4 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ38421.1 - 9.7e-07 28.3 0.0 9.9e-05 21.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ38421.1 - 0.00014 22.4 0.3 0.002 18.7 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38421.1 - 0.00014 21.1 0.1 0.00019 20.7 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KEZ38421.1 - 0.00041 19.7 0.1 0.00081 18.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEZ38421.1 - 0.00071 18.4 0.7 0.0015 17.3 0.7 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KEZ38421.1 - 0.042 13.1 0.6 0.087 12.1 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KEZ38421.1 - 0.17 10.6 0.1 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 MCRA family SQS_PSY PF00494.19 KEZ38422.1 - 7.5e-65 219.0 0.4 8.7e-65 218.8 0.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase SQS_PSY PF00494.19 KEZ38423.1 - 1.3e-61 208.4 2.5 1.9e-61 207.9 2.5 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase PSRT PF07636.11 KEZ38423.1 - 0.051 13.2 1.4 0.12 12.1 1.4 1.5 1 0 0 1 1 1 0 PSRT Serglycin PF04360.12 KEZ38423.1 - 0.22 11.5 3.1 0.41 10.6 3.1 1.4 1 0 0 1 1 1 0 Serglycin adh_short PF00106.25 KEZ38424.1 - 3.2e-44 150.7 0.0 4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38424.1 - 1.1e-25 90.6 0.0 1.4e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ38424.1 - 4.7e-08 33.1 1.0 8.1e-08 32.4 1.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEZ38424.1 - 0.0052 16.2 0.0 0.0074 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CpcD PF01383.21 KEZ38425.1 - 0.16 12.3 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain TetR_N PF00440.23 KEZ38426.1 - 3.8e-21 74.6 0.7 1.8e-20 72.4 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 KEZ38426.1 - 0.027 14.5 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 KEZ38426.1 - 0.085 12.7 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 KEZ38426.1 - 0.086 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 KEZ38426.1 - 0.13 11.8 0.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KEZ38426.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain MMPL PF03176.15 KEZ38427.1 - 4.4e-96 321.7 28.4 3e-57 194.1 7.5 2.1 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 KEZ38427.1 - 6.4e-05 20.8 19.1 0.00034 18.4 10.5 2.2 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family NUDIX PF00293.28 KEZ38428.1 - 3.4e-18 66.0 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Epimerase PF01370.21 KEZ38430.1 - 1.1e-19 70.9 0.0 1.8e-19 70.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEZ38430.1 - 3e-10 40.3 0.0 3.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ38430.1 - 1.6e-09 37.2 0.0 2.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ38430.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ38430.1 - 5.6e-05 22.4 0.0 0.00039 19.7 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein DapB_N PF01113.20 KEZ38430.1 - 0.0042 17.2 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KEZ38430.1 - 0.0056 15.8 0.2 0.022 13.9 0.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KEZ38430.1 - 0.007 16.6 0.2 0.024 14.9 0.2 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEZ38430.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KEZ38430.1 - 0.068 13.8 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.13 KEZ38430.1 - 0.29 10.6 1.0 0.86 9.1 1.0 1.7 1 1 0 1 1 1 0 NmrA-like family Ldh_1_N PF00056.23 KEZ38430.1 - 0.37 10.9 0.9 0.69 10.0 0.9 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FtsX PF02687.21 KEZ38431.1 - 0.0011 19.4 1.6 0.0011 19.4 1.6 5.7 7 0 0 7 7 7 2 FtsX-like permease family ABC_tran PF00005.27 KEZ38432.1 - 2.4e-33 115.5 0.0 3.1e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KEZ38432.1 - 2.6e-08 33.5 0.0 5.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ38432.1 - 8.6e-06 26.2 0.1 1.2e-05 25.8 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KEZ38432.1 - 5.3e-05 23.2 0.0 0.0089 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KEZ38432.1 - 0.00012 21.7 0.0 0.0035 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ38432.1 - 0.00024 21.4 0.1 0.0025 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEZ38432.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KEZ38432.1 - 0.00029 21.4 0.0 0.0004 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KEZ38432.1 - 0.00062 19.3 0.0 0.12 11.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEZ38432.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KEZ38432.1 - 0.0023 17.7 0.2 0.087 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KEZ38432.1 - 0.0033 17.4 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 KEZ38432.1 - 0.011 15.9 0.2 0.13 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KEZ38432.1 - 0.059 12.2 0.2 2.7 6.7 0.2 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 KEZ38432.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KEZ38432.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KEZ38432.1 - 0.076 12.9 0.1 0.54 10.2 0.0 2.2 2 1 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 KEZ38432.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 KEZ38432.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ38432.1 - 0.13 12.7 0.0 0.74 10.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KEZ38432.1 - 0.13 12.5 0.4 3.1 8.1 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KEZ38432.1 - 0.22 11.6 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PadR PF03551.14 KEZ38433.1 - 2e-12 46.9 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family AphA_like PF14557.6 KEZ38433.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator Vir_act_alpha_C PF10400.9 KEZ38433.1 - 0.0045 17.6 0.6 0.0082 16.8 0.6 1.4 1 0 0 1 1 1 1 Virulence activator alpha C-term HTH_7 PF02796.15 KEZ38434.1 - 0.00048 20.1 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase KfrA_N PF11740.8 KEZ38434.1 - 0.025 15.3 0.0 0.035 14.8 0.0 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HTH_28 PF13518.6 KEZ38434.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain ArdA PF07275.11 KEZ38436.1 - 1.5e-14 54.9 0.2 1.8e-14 54.7 0.2 1.1 1 0 0 1 1 1 1 Antirestriction protein (ArdA) AbiEii PF08843.11 KEZ38437.1 - 3.8e-11 43.4 1.2 7.2e-11 42.5 1.2 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF2204 PF09970.9 KEZ38437.1 - 0.0052 16.5 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) HTH_3 PF01381.22 KEZ38438.1 - 5.3e-11 42.4 0.0 8.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ38438.1 - 3.4e-08 33.7 3.0 3.4e-08 33.7 3.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ38438.1 - 7.1e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KEZ38438.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TetR_N PF00440.23 KEZ38438.1 - 0.095 12.5 2.1 0.66 9.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_24 PF13412.6 KEZ38438.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4037 PF13228.6 KEZ38439.1 - 6.3e-26 91.1 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) Glyoxalase PF00903.25 KEZ38440.1 - 1.3e-16 61.0 0.0 1.5e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ38440.1 - 2.7e-07 30.8 0.0 3.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEZ38440.1 - 1.7e-06 28.8 0.1 2.3e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KEZ38440.1 - 0.0016 18.3 0.0 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain DUF1275 PF06912.11 KEZ38441.1 - 1.6e-36 126.1 22.6 2e-36 125.7 22.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) NAD_binding_2 PF03446.15 KEZ38442.1 - 3.3e-47 160.6 1.0 3.3e-47 160.6 1.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEZ38442.1 - 3e-31 108.2 0.5 5.5e-31 107.4 0.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KEZ38442.1 - 1.5e-07 31.9 0.6 6e-07 30.0 0.0 2.3 2 2 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KEZ38442.1 - 0.00037 20.4 0.2 0.001 19.0 0.1 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ38442.1 - 0.00066 19.8 0.2 0.002 18.2 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ38442.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thump_like PF18096.1 KEZ38443.1 - 4.9e-18 64.8 0.7 1.6e-16 60.0 0.1 2.6 3 0 0 3 3 3 1 THUMP domain-like Methyltransf_15 PF09445.10 KEZ38443.1 - 0.026 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SmpB PF01668.18 KEZ38444.1 - 3.7e-57 192.3 0.1 4.2e-57 192.1 0.1 1.0 1 0 0 1 1 1 1 SmpB protein DUF222 PF02720.17 KEZ38445.1 - 4.8e-18 65.7 22.6 8.9e-18 64.8 22.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 KEZ38445.1 - 0.013 15.7 3.8 0.019 15.1 3.8 1.3 1 0 0 1 1 1 0 HNH endonuclease RHH_1 PF01402.21 KEZ38445.1 - 2.5 8.2 5.6 1.5 8.9 0.1 3.4 3 1 0 3 3 3 0 Ribbon-helix-helix protein, copG family FtsX_ECD PF18075.1 KEZ38446.1 - 5.3e-18 65.4 0.0 7.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 KEZ38446.1 - 7.8e-07 29.5 1.2 7.8e-07 29.5 1.2 2.6 3 0 0 3 3 3 1 FtsX-like permease family DUF2244 PF10003.9 KEZ38446.1 - 8 6.1 6.5 36 4.0 0.2 2.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) ABC_tran PF00005.27 KEZ38447.1 - 9.8e-32 110.3 0.0 1.5e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ38447.1 - 3.1e-10 40.4 0.0 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ38447.1 - 1e-06 29.3 0.1 1.7e-06 28.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ38447.1 - 5.8e-05 23.4 0.1 0.00041 20.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ38447.1 - 0.00014 22.1 0.1 0.00025 21.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KEZ38447.1 - 0.00047 19.6 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain cobW PF02492.19 KEZ38447.1 - 0.001 18.7 0.0 0.0036 16.9 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KEZ38447.1 - 0.0013 19.3 0.0 0.0059 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ38447.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KEZ38447.1 - 0.002 17.9 0.2 0.0075 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEZ38447.1 - 0.0033 17.3 0.1 0.0072 16.3 0.0 1.5 2 0 0 2 2 1 1 RsgA GTPase Viral_helicase1 PF01443.18 KEZ38447.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KEZ38447.1 - 0.0098 16.3 0.0 0.094 13.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEZ38447.1 - 0.01 15.8 0.2 0.027 14.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KEZ38447.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 KEZ38447.1 - 0.013 14.5 0.0 0.03 13.3 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KEZ38447.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KEZ38447.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KEZ38447.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 KEZ38447.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KEZ38447.1 - 0.026 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 KEZ38447.1 - 0.027 14.4 0.2 0.056 13.3 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KEZ38447.1 - 0.031 14.3 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KEZ38447.1 - 0.032 14.0 0.0 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEZ38447.1 - 0.037 14.3 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KEZ38447.1 - 0.044 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit T2SSE PF00437.20 KEZ38447.1 - 0.05 12.7 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 KEZ38447.1 - 0.052 13.2 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KEZ38447.1 - 0.056 13.0 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 KEZ38447.1 - 0.086 11.7 0.0 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.14 KEZ38447.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_23 PF13476.6 KEZ38447.1 - 0.096 13.2 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEZ38447.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ38447.1 - 0.16 11.9 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KEZ38447.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KEZ38447.1 - 0.22 11.3 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.8 KEZ38447.1 - 0.34 8.4 0.0 0.46 7.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 KEZ38447.1 - 0.35 9.5 0.0 15 4.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.6 KEZ38448.1 - 0.029 14.2 0.9 0.04 13.8 0.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PhnA_Zn_Ribbon PF08274.12 KEZ38448.1 - 0.033 14.2 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 KEZ38448.1 - 0.049 13.1 0.4 0.049 13.1 0.4 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zf-trcl PF13451.6 KEZ38448.1 - 4.8 7.1 6.5 3.8 7.5 2.0 2.2 2 1 0 2 2 2 0 Probable zinc-ribbon domain TP_methylase PF00590.20 KEZ38449.1 - 1e-41 143.2 3.4 1.4e-41 142.8 3.4 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Rieske_2 PF13806.6 KEZ38450.1 - 8.3e-37 125.3 0.0 9.3e-37 125.1 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KEZ38450.1 - 0.0005 20.0 0.0 0.00086 19.2 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.14 KEZ38451.1 - 1.8e-47 162.0 1.5 2.7e-47 161.4 1.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KEZ38451.1 - 1.4e-19 70.2 8.8 2.7e-13 50.1 5.4 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 KEZ38451.1 - 4.3e-18 65.3 0.0 9e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KEZ38451.1 - 2.6e-17 63.1 0.4 2.2e-15 56.9 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 KEZ38451.1 - 2.5e-10 40.1 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KEZ38451.1 - 3e-07 30.2 0.0 7.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 KEZ38451.1 - 5.4e-05 22.6 0.0 0.0003 20.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38451.1 - 0.0058 15.8 0.6 1.2 8.2 1.4 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KEZ38451.1 - 0.014 14.7 0.7 0.031 13.6 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KEZ38451.1 - 0.039 14.2 0.6 0.37 11.0 0.3 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KEZ38451.1 - 0.042 14.3 0.8 13 6.3 0.0 3.5 4 0 0 4 4 3 0 Putative NAD(P)-binding TrkA_N PF02254.18 KEZ38451.1 - 0.076 13.3 0.1 4 7.7 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 KEZ38451.1 - 0.088 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KEZ38451.1 - 0.14 11.4 0.5 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KEZ38451.1 - 1.3 9.0 3.3 3.5 7.6 0.1 3.0 2 1 0 3 3 3 0 FAD-NAD(P)-binding HEM4 PF02602.15 KEZ38452.1 - 3.5e-40 137.8 0.1 4.8e-40 137.3 0.1 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Trans_reg_C PF00486.28 KEZ38452.1 - 4.6e-12 45.8 0.0 1.2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Polysacc_deac_1 PF01522.21 KEZ38453.1 - 2.8e-21 75.7 0.0 4.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PCRF PF03462.18 KEZ38454.1 - 9.2e-57 192.0 0.0 1.9e-56 191.0 0.0 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KEZ38454.1 - 3.2e-37 127.0 0.0 6.1e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 RF-1 domain ABC_tran_CTD PF16326.5 KEZ38454.1 - 0.041 14.1 0.2 0.041 14.1 0.2 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4055 PF13264.6 KEZ38454.1 - 0.056 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) TPR_MalT PF17874.1 KEZ38455.1 - 0.0081 15.6 12.7 0.03 13.7 4.8 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_12 PF13424.6 KEZ38455.1 - 0.01 16.1 9.0 0.079 13.3 1.6 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Tad PF13400.6 KEZ38456.1 - 1.3e-07 31.8 15.2 2.9e-07 30.7 14.3 2.1 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like Collagen PF01391.18 KEZ38456.1 - 0.00042 20.0 8.1 0.00074 19.2 8.1 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mago-bind PF09282.10 KEZ38456.1 - 1.2 9.1 4.6 16 5.5 1.7 3.1 1 1 1 2 2 2 0 Mago binding Peptidase_S15 PF02129.18 KEZ38457.1 - 1.7e-20 73.7 0.0 2.6e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEZ38457.1 - 2e-17 63.9 0.4 3.7e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain AXE1 PF05448.12 KEZ38457.1 - 0.0023 16.7 0.1 0.0091 14.7 0.1 1.8 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KEZ38457.1 - 0.005 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ38457.1 - 0.025 14.2 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KEZ38457.1 - 0.034 14.0 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold APH PF01636.23 KEZ38458.1 - 3.5e-24 86.1 1.2 3.5e-24 86.1 1.2 4.1 3 2 1 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ38458.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase TPR_19 PF14559.6 KEZ38458.1 - 0.00032 21.1 0.4 0.00032 21.1 0.4 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ38458.1 - 0.00073 20.0 1.6 0.00073 20.0 1.6 3.2 3 2 0 3 3 3 1 AAA ATPase domain TPR_14 PF13428.6 KEZ38458.1 - 0.034 15.0 30.7 0.52 11.3 0.2 7.5 4 1 2 6 6 6 0 Tetratricopeptide repeat EcKinase PF02958.20 KEZ38458.1 - 0.052 12.9 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PTS_IIA PF02255.16 KEZ38458.1 - 0.062 13.4 0.4 0.41 10.7 0.0 2.5 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit AAA_22 PF13401.6 KEZ38458.1 - 0.15 12.4 0.2 0.88 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KEZ38458.1 - 0.18 11.7 0.4 6.2 6.7 0.4 2.4 1 1 0 1 1 1 0 NACHT domain TPR_4 PF07721.14 KEZ38458.1 - 0.57 11.0 0.1 0.57 11.0 0.1 8.3 10 0 0 10 10 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ38458.1 - 1.4 9.2 26.7 0.056 13.8 2.7 5.0 3 1 3 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ38458.1 - 2.4 9.0 5.3 51 4.8 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TadE PF07811.12 KEZ38461.1 - 1.2e-11 44.7 3.2 3.4e-11 43.2 3.2 1.8 1 0 0 1 1 1 1 TadE-like protein T2SSF PF00482.23 KEZ38463.1 - 7.5e-14 51.8 5.8 7.5e-14 51.8 5.8 2.6 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F T2SSF PF00482.23 KEZ38464.1 - 4e-10 39.7 0.4 4e-10 39.7 0.4 2.7 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F RseC_MucC PF04246.12 KEZ38464.1 - 0.0037 17.2 0.9 0.84 9.6 0.1 2.4 2 0 0 2 2 2 2 Positive regulator of sigma(E), RseC/MucC PrgI PF12666.7 KEZ38464.1 - 0.65 10.7 6.2 0.69 10.7 0.3 2.9 3 0 0 3 3 3 0 PrgI family protein T2SSE PF00437.20 KEZ38465.1 - 2.5e-54 184.2 0.2 3.1e-54 183.9 0.2 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KEZ38465.1 - 0.0077 15.6 0.4 0.019 14.3 0.1 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family GatB_Yqey PF02637.18 KEZ38465.1 - 0.038 13.9 0.0 0.15 12.0 0.0 2.0 3 0 0 3 3 3 0 GatB domain Gp_dh_C PF02800.20 KEZ38465.1 - 0.076 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain PAS_4 PF08448.10 KEZ38466.1 - 2.9e-17 62.9 6.9 3.8e-08 33.6 0.1 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KEZ38466.1 - 5.6e-13 48.9 0.0 3.8e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KEZ38466.1 - 1.4e-09 37.7 0.1 0.0028 17.6 0.1 2.9 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 KEZ38466.1 - 1.7e-08 34.7 0.0 0.00062 20.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KEZ38466.1 - 1.3e-07 31.8 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 KEZ38466.1 - 7.9e-06 26.0 0.0 8.8e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KEZ38466.1 - 0.00089 19.4 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain DUF4332 PF14229.6 KEZ38467.1 - 0.013 15.7 0.2 0.057 13.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4332) HHH_5 PF14520.6 KEZ38467.1 - 0.015 15.9 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain LapA_dom PF06305.11 KEZ38467.1 - 0.017 14.9 0.2 0.058 13.2 0.2 1.9 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain IMS_HHH PF11798.8 KEZ38467.1 - 0.023 15.0 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif Cdd1 PF11731.8 KEZ38467.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus Tropomyosin PF00261.20 KEZ38467.1 - 0.14 11.5 13.6 1.1 8.6 3.3 2.2 2 0 0 2 2 2 0 Tropomyosin SOGA PF11365.8 KEZ38467.1 - 0.81 10.8 4.5 0.9 10.7 0.9 2.3 2 0 0 2 2 2 0 Protein SOGA Lebercilin PF15619.6 KEZ38467.1 - 1.8 8.2 8.0 0.31 10.7 1.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Patatin PF01734.22 KEZ38469.1 - 3.3e-21 76.4 3.1 5.7e-21 75.6 3.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase HTH_3 PF01381.22 KEZ38470.1 - 2.3e-08 33.9 0.1 1e-07 31.9 0.0 2.1 3 0 0 3 3 3 1 Helix-turn-helix HTH_31 PF13560.6 KEZ38470.1 - 2.5e-07 31.0 6.1 9.1e-07 29.1 0.6 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KEZ38470.1 - 0.0049 16.8 0.1 0.021 14.9 0.1 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KEZ38470.1 - 0.18 11.7 1.4 0.56 10.1 0.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain ParA PF10609.9 KEZ38471.1 - 0.00016 21.2 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KEZ38471.1 - 0.00039 20.4 0.0 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KEZ38471.1 - 0.0039 17.3 0.0 0.0076 16.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RecA PF00154.21 KEZ38471.1 - 0.08 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein SAF PF08666.12 KEZ38472.1 - 1e-06 29.2 0.1 1.9e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 SAF domain RcpC PF16976.5 KEZ38472.1 - 0.0025 17.8 0.6 0.22 11.6 0.0 2.5 2 0 0 2 2 2 1 Flp pilus assembly protein RcpC/CpaB RskA PF10099.9 KEZ38472.1 - 0.0045 17.3 2.5 0.0045 17.3 2.5 2.2 2 0 0 2 2 2 1 Anti-sigma-K factor rskA ChapFlgA PF13144.6 KEZ38472.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation BIV_Env PF05858.12 KEZ38472.1 - 0.26 9.4 0.2 0.35 9.0 0.2 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) HTH_17 PF12728.7 KEZ38473.1 - 6.5e-14 51.8 0.0 7.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_AlpA PF05930.12 KEZ38473.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) LysM PF01476.20 KEZ38475.1 - 8e-06 25.8 0.0 2.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 LysM domain Yip1 PF04893.17 KEZ38475.1 - 0.55 9.9 9.0 1 9.1 9.0 1.4 1 1 0 1 1 1 0 Yip1 domain SecA_DEAD PF07517.14 KEZ38477.1 - 2.4e-125 417.6 0.1 3.6e-125 417.0 0.1 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 KEZ38477.1 - 1.4e-65 221.1 0.1 2.6e-65 220.2 0.1 1.5 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 KEZ38477.1 - 2.5e-36 124.7 0.1 5.9e-36 123.5 0.1 1.7 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 KEZ38477.1 - 1.5e-09 37.6 8.1 2.3e-09 37.0 8.1 1.3 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 KEZ38477.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ38477.1 - 0.044 14.1 0.9 0.38 11.1 0.0 2.5 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Acetyltransf_3 PF13302.7 KEZ38478.1 - 5.5e-24 85.4 0.0 6.8e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ38478.1 - 0.0074 16.5 0.0 0.0098 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KEZ38478.1 - 0.045 13.4 0.1 0.071 12.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_r1t_holin PF16945.5 KEZ38478.1 - 0.069 13.4 0.4 0.069 13.4 0.4 1.6 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin Response_reg PF00072.24 KEZ38479.1 - 3.4e-28 98.1 1.6 7.3e-28 97.0 1.6 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KEZ38479.1 - 1.6e-23 82.0 0.4 2.8e-23 81.2 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KEZ38479.1 - 6.2e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 KEZ38479.1 - 4e-06 26.5 1.0 0.00018 21.2 0.4 2.9 2 1 0 2 2 2 1 HTH DNA binding domain Sigma70_r4 PF04545.16 KEZ38479.1 - 1.4e-05 24.5 0.1 2.8e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KEZ38479.1 - 0.00031 20.2 0.1 0.00056 19.4 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KEZ38479.1 - 0.00032 20.4 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ38479.1 - 0.00033 20.4 0.0 0.00086 19.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.6 KEZ38479.1 - 0.0011 18.8 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_40 PF14493.6 KEZ38479.1 - 0.0023 18.3 0.8 0.0086 16.5 0.2 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KEZ38479.1 - 0.0045 17.0 0.0 0.0099 15.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 KEZ38479.1 - 0.0067 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 KEZ38479.1 - 0.015 14.7 0.0 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF2089 PF09862.9 KEZ38479.1 - 0.017 15.1 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Mga PF05043.13 KEZ38479.1 - 0.019 15.5 0.1 0.05 14.2 0.1 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_28 PF13518.6 KEZ38479.1 - 0.02 15.0 0.6 0.099 12.8 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Phage_terminase PF10668.9 KEZ38479.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 Phage terminase small subunit HTH_11 PF08279.12 KEZ38479.1 - 0.05 13.5 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 KEZ38479.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosom_S30AE_C PF16321.5 KEZ38480.1 - 1.1e-20 73.1 0.0 1.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 KEZ38480.1 - 1.1e-20 74.2 0.2 1.6e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Pribosyltran PF00156.27 KEZ38481.1 - 1.6e-05 24.5 0.1 7.4e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KEZ38481.1 - 0.0045 16.5 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 KEZ38481.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase GPDPase_memb PF10110.9 KEZ38482.1 - 4.4e-06 25.7 3.7 7.3e-06 25.0 3.7 1.3 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase UPF0259 PF06790.11 KEZ38482.1 - 0.0046 16.8 6.6 0.0074 16.1 6.2 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0259) DUF975 PF06161.11 KEZ38482.1 - 0.17 11.6 6.1 1.5 8.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF975) DUF1129 PF06570.11 KEZ38482.1 - 1.1 8.7 3.2 3.5 7.1 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4129 PF13559.6 KEZ38483.1 - 1.2e-27 95.9 3.5 1.2e-27 95.9 3.5 2.9 3 2 0 3 3 3 1 Domain of unknown function (DUF4129) DUF4381 PF14316.6 KEZ38483.1 - 0.59 10.4 3.2 0.44 10.8 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4350 PF14258.6 KEZ38484.1 - 3.9e-18 65.6 1.6 5.1e-18 65.3 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) AAA_3 PF07726.11 KEZ38485.1 - 1.8e-62 209.0 0.1 2.6e-62 208.5 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KEZ38485.1 - 1.5e-20 72.8 2.6 1.5e-20 72.8 2.6 2.9 3 0 0 3 3 3 1 AAA lid domain AAA_5 PF07728.14 KEZ38485.1 - 1.7e-12 47.5 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KEZ38485.1 - 4.7e-08 32.4 0.0 7.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KEZ38485.1 - 0.00035 20.0 3.0 0.0044 16.4 0.2 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ38485.1 - 0.00053 19.7 0.0 0.0022 17.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 KEZ38485.1 - 0.0074 16.7 0.0 0.027 14.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEZ38485.1 - 0.022 14.5 0.1 0.14 11.9 0.1 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF58 PF01882.18 KEZ38486.1 - 1.8e-20 73.0 0.7 3.7e-20 72.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF58 DUF11 PF01345.18 KEZ38486.1 - 0.00027 21.2 0.3 0.0033 17.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF11 VWA_2 PF13519.6 KEZ38486.1 - 0.006 17.2 0.0 0.017 15.7 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain SBP_bac_3 PF00497.20 KEZ38487.1 - 9.3e-37 126.6 0.0 1.1e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KEZ38487.1 - 0.0034 17.5 0.0 0.0092 16.2 0.0 1.7 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site ABC2_membrane_3 PF12698.7 KEZ38487.1 - 0.19 10.8 0.0 1.5 7.9 0.0 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein SpoIIM PF01944.17 KEZ38488.1 - 2.3e-37 128.4 5.0 3.5e-37 127.8 5.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein M DUF1129 PF06570.11 KEZ38488.1 - 0.06 12.8 1.9 0.12 11.9 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RDD PF06271.12 KEZ38489.1 - 3.5e-18 66.2 3.5 4.9e-18 65.7 3.5 1.2 1 0 0 1 1 1 1 RDD family TGT_C1 PF14809.6 KEZ38489.1 - 0.099 13.0 0.2 0.17 12.2 0.2 1.3 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation Transgly PF00912.22 KEZ38490.1 - 2.8e-61 206.1 0.0 4.2e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KEZ38490.1 - 1.1e-30 106.9 1.0 2.3e-30 105.9 1.0 1.5 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain bact-PGI_C PF10432.9 KEZ38491.1 - 1.8e-50 171.0 0.0 3.3e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 KEZ38491.1 - 7.4e-05 22.6 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KEZ38491.1 - 0.013 15.5 4.7 0.096 12.7 0.8 2.6 2 0 0 2 2 2 0 SIS domain Trm112p PF03966.16 KEZ38492.1 - 1.8e-06 28.4 1.2 2.3e-05 24.9 1.2 2.0 1 1 0 1 1 1 1 Trm112p-like protein PGM_PMM_I PF02878.16 KEZ38493.1 - 1.4e-27 96.1 0.1 2.4e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KEZ38493.1 - 4.6e-27 94.5 0.0 8.3e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEZ38493.1 - 8e-25 87.5 0.0 1.9e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KEZ38493.1 - 3.9e-17 62.2 0.0 9.9e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3499 PF12005.8 KEZ38494.1 - 3.7e-42 143.8 0.2 5.2e-42 143.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3499) Zincin_1 PF06262.11 KEZ38495.1 - 2.6e-10 40.3 0.2 5.6e-10 39.2 0.2 1.5 1 1 0 1 1 1 1 Zincin-like metallopeptidase PMI_typeI PF01238.21 KEZ38496.1 - 5.8e-48 164.0 0.0 1.6e-22 80.3 0.0 2.9 2 1 0 2 2 2 2 Phosphomannose isomerase type I Glyco_tranf_2_3 PF13641.6 KEZ38497.1 - 5.5e-09 36.3 0.8 3.3e-08 33.7 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 YfhO PF09586.10 KEZ38497.1 - 0.19 10.0 0.0 0.44 8.7 0.0 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF2079 PF09852.9 KEZ38497.1 - 5.9 5.6 6.4 13 4.5 6.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Whib PF02467.16 KEZ38498.1 - 3.3e-26 91.7 3.6 6.5e-26 90.7 3.6 1.4 1 0 0 1 1 1 1 Transcription factor WhiB BNIP2 PF12496.8 KEZ38498.1 - 0.26 11.7 5.1 0.55 10.7 5.1 1.6 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Radical_SAM PF04055.21 KEZ38499.1 - 9.8e-26 91.1 0.0 7.7e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 Radical SAM superfamily TetR_N PF00440.23 KEZ38501.1 - 1.7e-14 53.3 0.4 2.8e-14 52.6 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.12 KEZ38501.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 UPF0052 PF01933.18 KEZ38502.1 - 6.7e-60 202.8 0.1 8.1e-60 202.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 F420_ligase PF01996.16 KEZ38503.1 - 1.3e-45 155.7 1.2 3.3e-32 111.8 0.2 2.2 1 1 1 2 2 2 2 F420-0:Gamma-glutamyl ligase Nitroreductase PF00881.24 KEZ38503.1 - 1.1e-29 103.6 0.0 1.6e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KEZ38503.1 - 0.00024 20.8 0.3 0.6 9.6 0.0 2.7 2 1 0 2 2 2 2 Putative TM nitroreductase DUF3105 PF11303.8 KEZ38504.1 - 3.1e-35 121.1 0.0 4.8e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) Phosphoesterase PF04185.14 KEZ38505.1 - 1.1e-34 120.3 4.0 4.5e-31 108.3 0.7 2.9 1 1 1 2 2 2 2 Phosphoesterase family DNA_pol3_beta_2 PF02767.16 KEZ38506.1 - 1.6e-24 86.4 0.0 8.1e-20 71.2 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 KEZ38506.1 - 3.8e-24 85.1 0.0 5.2e-16 58.9 0.0 3.6 4 0 0 4 4 4 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 KEZ38506.1 - 1.9e-17 63.2 0.0 3.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III beta subunit, C-terminal domain NTP_transferase PF00483.23 KEZ38507.1 - 2e-42 145.5 0.0 2.4e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ38507.1 - 2.6e-12 47.4 0.2 3.8e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KEZ38507.1 - 1.3e-11 43.7 16.8 2.3e-05 23.9 3.8 3.9 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ38507.1 - 0.016 15.0 21.6 0.26 11.0 4.1 4.2 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KEZ38507.1 - 0.28 9.3 0.1 0.39 8.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Glyco_tranf_2_3 PF13641.6 KEZ38508.1 - 2.2e-20 73.6 0.0 7.6e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ38508.1 - 8.4e-20 71.3 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ38508.1 - 2.9e-08 33.4 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KEZ38508.1 - 6.2e-06 26.3 1.1 9.2e-06 25.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 KEZ38508.1 - 0.00094 18.7 0.0 0.0072 15.8 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KEZ38508.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glycos_transf_1 PF00534.20 KEZ38509.1 - 2.7e-20 72.6 0.0 3.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ38509.1 - 1.7e-18 67.2 1.4 4.1e-18 65.9 1.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEZ38509.1 - 2.7e-17 63.5 0.0 6.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ38509.1 - 9.6e-15 55.4 8.8 9.6e-15 55.4 8.8 2.9 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ38509.1 - 5.9e-11 42.6 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ38510.1 - 8.1e-25 87.3 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ38510.1 - 1.4e-19 70.9 0.3 2.5e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ38510.1 - 1.6e-10 41.3 7.0 1.1e-08 35.3 1.2 3.2 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KEZ38510.1 - 1.3e-08 35.1 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peripla_BP_4 PF13407.6 KEZ38510.1 - 0.02 14.4 0.5 0.036 13.6 0.5 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain GGDEF_2 PF17853.1 KEZ38510.1 - 0.042 14.1 0.9 0.24 11.7 0.9 2.4 1 1 0 1 1 1 0 GGDEF-like domain DUF3040 PF11239.8 KEZ38511.1 - 0.053 13.8 0.2 0.068 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 KEZ38511.1 - 0.77 9.8 7.1 0.92 9.6 7.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3309 PF11752.8 KEZ38511.1 - 3.3 7.8 10.0 9.2 6.4 10.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3309) Methyltransf_11 PF08241.12 KEZ38512.1 - 1.4e-18 67.3 0.1 2.1e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38512.1 - 6.3e-15 55.7 0.1 1.1e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38512.1 - 4.1e-13 49.5 0.0 5.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38512.1 - 3.1e-10 39.8 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KEZ38512.1 - 5.2e-09 36.1 0.0 6.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KEZ38512.1 - 5e-08 31.9 0.0 5.7e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KEZ38512.1 - 1.2e-06 29.2 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KEZ38512.1 - 0.0031 16.5 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KEZ38512.1 - 0.0054 16.0 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Glyco_trans_1_4 PF13692.6 KEZ38513.1 - 1.1e-18 68.0 0.1 2.1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ38513.1 - 1.6e-15 57.1 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ38513.1 - 8.6e-06 25.9 3.7 8.6e-06 25.9 3.7 2.7 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KEZ38513.1 - 1.5e-05 25.5 20.0 1.5e-05 25.5 20.0 2.6 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_2 PF00535.26 KEZ38514.1 - 2.9e-26 92.3 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ38514.1 - 4.2e-15 56.3 0.1 5.1e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEZ38514.1 - 0.0076 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SDF PF00375.18 KEZ38514.1 - 0.018 14.1 1.9 0.024 13.7 1.9 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Glyco_transf_21 PF13506.6 KEZ38514.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KEZ38514.1 - 0.076 13.5 0.0 0.34 11.5 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 MAP1B_neuraxin PF00414.17 KEZ38514.1 - 0.49 10.0 1.4 0.99 9.1 1.4 1.4 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat Hexapep_2 PF14602.6 KEZ38515.1 - 9.8e-08 31.6 0.3 9.8e-08 31.6 0.3 2.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KEZ38515.1 - 3.2e-07 29.8 0.5 3.2e-07 29.8 0.5 3.0 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) DUF2142 PF09913.9 KEZ38516.1 - 1.2e-13 50.7 6.2 1.2e-13 50.7 6.2 2.4 2 1 0 2 2 2 1 Predicted membrane protein (DUF2142) PMT_2 PF13231.6 KEZ38516.1 - 5.9e-11 42.8 4.9 5.9e-11 42.8 4.9 3.0 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pkinase PF00069.25 KEZ38517.1 - 1e-33 116.8 0.0 1.5e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38517.1 - 6.6e-24 84.6 0.0 9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KEZ38517.1 - 1.9e-18 66.5 3.2 2.2e-06 28.3 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEZ38517.1 - 4.6e-06 25.8 0.0 0.072 12.0 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein APH PF01636.23 KEZ38517.1 - 9e-06 25.8 7.1 0.0068 16.4 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ38517.1 - 0.00091 18.1 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ANAPC4_WD40 PF12894.7 KEZ38517.1 - 0.0012 19.1 0.0 2.4 8.5 0.0 3.2 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Kdo PF06293.14 KEZ38517.1 - 0.004 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome_A_N PF10584.9 KEZ38517.1 - 0.004 16.8 0.7 1.9 8.2 0.0 3.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 KEZ38517.1 - 0.0049 16.8 0.1 5.7 7.0 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat RIO1 PF01163.22 KEZ38517.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Cytochrom_D1 PF02239.16 KEZ38517.1 - 0.095 11.2 0.0 0.8 8.2 0.0 1.9 1 1 1 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 KEZ38518.1 - 6.2e-25 87.0 11.4 5.1e-09 36.6 0.0 4.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ38518.1 - 1.8e-12 47.4 0.0 0.0007 19.9 0.0 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ38518.1 - 1.5e-08 34.0 0.1 0.018 14.0 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ38518.1 - 2.1e-05 24.3 0.4 0.56 10.2 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KEZ38518.1 - 5.8e-05 22.6 0.2 0.21 10.9 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 KEZ38518.1 - 0.015 15.0 0.1 8 6.2 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature eIF2A PF08662.11 KEZ38518.1 - 0.073 12.9 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Methyltransf_24 PF13578.6 KEZ38519.1 - 7.6e-12 46.2 0.7 2.5e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Hydrolase_like PF13242.6 KEZ38520.1 - 0.0036 17.3 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like ABC2_membrane PF01061.24 KEZ38521.1 - 2.1e-19 69.8 18.2 3.3e-19 69.2 18.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KEZ38522.1 - 2e-18 67.2 0.0 4.8e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ38522.1 - 6.4e-05 22.9 5.3 0.00052 19.9 0.5 2.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 KEZ38522.1 - 0.00029 19.9 0.2 0.0007 18.7 0.2 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KEZ38522.1 - 0.0011 18.7 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ38522.1 - 0.0073 16.7 0.1 0.012 16.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KEZ38522.1 - 0.037 13.7 0.1 0.072 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ38522.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ38522.1 - 0.077 13.5 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KEZ38522.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 KEZ38522.1 - 0.13 11.6 0.1 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KEZ38522.1 - 0.15 12.6 0.3 0.32 11.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ38522.1 - 0.17 12.3 0.0 1.3 9.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KEZ38522.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_15 PF13175.6 KEZ38522.1 - 0.23 11.2 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Glycos_transf_2 PF00535.26 KEZ38523.1 - 1.6e-17 63.8 0.0 2.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ38523.1 - 5.2e-17 62.5 0.1 8.8e-09 35.6 0.0 2.4 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KEZ38523.1 - 2.3e-05 24.4 0.1 4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 KEZ38523.1 - 0.0011 19.4 0.0 0.008 16.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glycos_transf_1 PF00534.20 KEZ38524.1 - 7e-13 48.5 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ38524.1 - 8.5e-09 35.9 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KEZ38524.1 - 2e-05 24.9 0.1 3.6e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ38524.1 - 0.0001 22.4 0.7 0.089 12.8 0.3 2.8 2 1 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KEZ38524.1 - 0.014 15.8 4.2 0.014 15.8 4.2 3.8 2 2 1 3 3 3 0 Glycosyl transferase 4-like domain Exostosin PF03016.15 KEZ38524.1 - 0.18 11.0 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Exostosin family MFS_1 PF07690.16 KEZ38527.1 - 3.8e-52 177.4 59.6 2.9e-51 174.5 57.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ38527.1 - 1.7e-13 49.9 29.6 4e-13 48.7 29.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEZ38527.1 - 6.1e-12 45.1 11.5 6.1e-12 45.1 11.5 2.9 1 1 2 3 3 3 2 Sugar (and other) transporter TetR_C_14 PF17754.1 KEZ38528.1 - 2e-17 63.1 4.8 2e-17 63.1 4.8 1.8 2 0 0 2 2 2 1 MftR C-terminal domain TetR_N PF00440.23 KEZ38528.1 - 4.5e-13 48.8 0.3 1.4e-12 47.1 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 KEZ38528.1 - 0.0075 16.0 1.5 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain 2_5_RNA_ligase2 PF13563.6 KEZ38528.1 - 0.0089 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily HTH_Tnp_1_2 PF13022.6 KEZ38528.1 - 0.041 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase RmlD_sub_bind PF04321.17 KEZ38529.1 - 1.9e-99 332.4 0.3 2.3e-99 332.1 0.3 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KEZ38529.1 - 9.1e-17 61.3 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ38529.1 - 8.6e-09 35.2 0.0 9.5e-08 31.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ38529.1 - 9.9e-07 28.2 0.0 2.3e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KEZ38529.1 - 6.4e-06 25.4 0.0 3.2e-05 23.1 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEZ38529.1 - 4.5e-05 22.7 0.1 0.00053 19.2 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein PMT_2 PF13231.6 KEZ38530.1 - 2.1e-09 37.8 4.2 2.1e-09 37.8 4.2 2.9 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 KEZ38530.1 - 4.3e-05 23.2 1.9 4.3e-05 23.2 1.9 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2448 PF10476.9 KEZ38530.1 - 1.6 8.5 4.7 1.8 8.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) NTP_transferase PF00483.23 KEZ38531.1 - 5.1e-54 183.5 0.0 6.1e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ38531.1 - 4.9e-09 36.7 0.2 7.7e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain LytR_cpsA_psr PF03816.14 KEZ38532.1 - 2.1e-44 151.3 0.0 3.3e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 KEZ38532.1 - 6e-16 59.2 0.7 1.5e-15 57.9 0.7 1.7 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator DUF3670 PF12419.8 KEZ38532.1 - 0.018 14.9 0.2 0.042 13.7 0.2 1.6 1 0 0 1 1 1 0 SNF2 Helicase protein LytR_cpsA_psr PF03816.14 KEZ38533.1 - 2.7e-29 102.3 0.0 3.9e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 KEZ38533.1 - 1.5e-12 48.3 0.7 6e-12 46.4 0.7 2.1 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator AMP-binding PF00501.28 KEZ38534.1 - 2e-12 46.4 0.0 5e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme UDPG_MGDP_dh_N PF03721.14 KEZ38535.1 - 6.4e-50 169.3 0.0 9.4e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KEZ38535.1 - 6.3e-30 103.7 0.0 3.3e-28 98.2 0.0 2.6 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KEZ38535.1 - 1.5e-29 102.1 0.0 2.9e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KEZ38535.1 - 3.4e-07 30.6 0.0 5.1e-06 26.7 0.0 2.7 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KEZ38535.1 - 0.0094 15.9 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ38535.1 - 0.027 13.8 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ38535.1 - 0.032 14.8 3.0 4.3 8.0 0.0 4.2 4 1 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Pro_CA PF00484.19 KEZ38536.1 - 1.6e-11 44.7 1.3 2.8e-09 37.5 1.3 2.2 1 1 0 1 1 1 1 Carbonic anhydrase GtrA PF04138.14 KEZ38537.1 - 7.6e-23 81.0 7.4 9.1e-23 80.7 7.4 1.1 1 0 0 1 1 1 1 GtrA-like protein ATG22 PF11700.8 KEZ38537.1 - 0.045 12.4 2.5 0.053 12.1 2.5 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF5353 PF17304.2 KEZ38537.1 - 3.3 7.5 5.8 1.1 9.1 1.5 2.4 3 1 0 3 3 3 0 Family of unknown function (DUF5353) TetR_C_11 PF16859.5 KEZ38538.1 - 2.2e-29 102.1 2.3 2.2e-29 102.1 2.3 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KEZ38538.1 - 5.2e-13 48.6 0.1 1.8e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 KEZ38538.1 - 0.0003 21.0 3.5 0.00062 19.9 1.0 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 KEZ38538.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain Lin-8 PF03353.15 KEZ38539.1 - 0.026 14.1 3.9 0.13 11.8 3.8 1.9 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3357 PF11837.8 KEZ38539.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PAT1 PF09770.9 KEZ38539.1 - 1.8 6.8 12.8 2.5 6.3 12.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bPH_2 PF03703.14 KEZ38542.1 - 1.2e-17 63.9 0.3 1.6e-17 63.5 0.3 1.2 1 0 0 1 1 1 1 Bacterial PH domain BPL_LplA_LipB PF03099.19 KEZ38543.1 - 6.1e-13 48.8 0.0 9.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KEZ38543.1 - 9.7e-07 28.6 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB_2 PF16917.5 KEZ38543.1 - 0.025 14.1 1.6 0.034 13.7 0.1 1.8 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family Carboxyl_trans PF01039.22 KEZ38544.1 - 5.2e-197 655.4 0.0 5.9e-197 655.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KEZ38544.1 - 0.0019 17.7 0.1 0.0038 16.8 0.1 1.4 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) DUF2862 PF11061.8 KEZ38544.1 - 0.21 11.4 0.4 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) ACC_epsilon PF13822.6 KEZ38545.1 - 3.1e-14 53.4 6.9 4.6e-14 52.8 6.9 1.3 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit CPSase_L_D2 PF02786.17 KEZ38546.1 - 8.1e-73 244.4 0.0 1.2e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEZ38546.1 - 3.2e-41 140.3 0.5 7.4e-41 139.1 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ38546.1 - 2.1e-34 117.9 0.0 4.8e-34 116.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEZ38546.1 - 7.3e-18 64.2 1.3 2.2e-17 62.7 0.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEZ38546.1 - 7.8e-10 38.4 0.9 1.8e-06 27.7 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KEZ38546.1 - 1.1e-06 28.3 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KEZ38546.1 - 6.6e-05 23.6 0.3 0.25 12.1 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KEZ38546.1 - 0.00021 20.6 0.7 0.15 11.3 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Dala_Dala_lig_C PF07478.13 KEZ38546.1 - 0.00022 20.8 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus LAL_C2 PF18603.1 KEZ38546.1 - 0.005 17.0 0.7 0.072 13.3 0.0 3.3 3 0 0 3 3 3 1 L-amino acid ligase C-terminal domain 2 DUF5313 PF17240.2 KEZ38547.1 - 2.8e-19 69.7 0.0 3.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5313) Pyr_redox_2 PF07992.14 KEZ38548.1 - 1.7e-58 198.2 0.8 2.2e-58 197.8 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEZ38548.1 - 2.4e-25 88.9 0.1 1.2e-24 86.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEZ38548.1 - 2.3e-20 72.9 8.6 3.2e-17 62.8 0.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ38548.1 - 3.3e-11 43.0 0.0 3.3e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38548.1 - 1.2e-08 34.5 7.0 0.0018 17.4 2.4 4.1 4 0 0 4 4 4 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KEZ38548.1 - 0.00014 21.2 10.1 0.037 13.3 2.5 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KEZ38548.1 - 0.00045 20.7 0.3 0.6 10.6 0.0 2.6 2 0 0 2 2 2 2 XdhC Rossmann domain Glyco_trans_4_4 PF13579.6 KEZ38548.1 - 0.00089 19.7 3.1 0.15 12.5 1.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain NAD_binding_8 PF13450.6 KEZ38548.1 - 0.005 17.0 6.8 0.097 12.9 0.2 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DFP PF04127.15 KEZ38548.1 - 0.0066 16.3 0.7 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein HI0933_like PF03486.14 KEZ38548.1 - 0.016 13.9 7.3 0.24 10.1 1.3 3.9 3 1 2 5 5 5 0 HI0933-like protein Glyco_transf_4 PF13439.6 KEZ38548.1 - 0.021 14.8 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase Family 4 K_oxygenase PF13434.6 KEZ38548.1 - 0.03 13.5 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KEZ38548.1 - 0.039 14.4 1.7 4 7.9 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KEZ38548.1 - 0.054 12.6 16.4 3.9 6.5 5.1 3.6 3 1 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KEZ38548.1 - 0.056 12.8 12.9 0.023 14.1 4.1 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ38548.1 - 0.36 10.0 5.5 1.5 8.0 1.2 2.3 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KEZ38548.1 - 0.42 9.4 5.0 0.32 9.8 1.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KEZ38548.1 - 0.53 10.1 4.2 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AIG2_2 PF13772.6 KEZ38549.1 - 9.2e-22 77.3 0.1 1.2e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KEZ38549.1 - 2.9e-11 44.0 0.0 3.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_M20 PF01546.28 KEZ38550.1 - 2.5e-26 92.7 0.1 3.3e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ38550.1 - 2e-07 30.9 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain GCS2 PF04107.13 KEZ38551.1 - 3.2e-62 210.5 0.1 3.8e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) tRNA-synt_2 PF00152.20 KEZ38552.1 - 6.8e-95 317.8 0.0 8.3e-95 317.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 KEZ38552.1 - 5.4e-21 74.6 0.0 9e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 KEZ38552.1 - 1e-12 47.8 0.2 1.8e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PNP_UDP_1 PF01048.20 KEZ38554.1 - 1.5e-40 139.0 0.7 1.8e-40 138.7 0.7 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Chorion_S16 PF05836.12 KEZ38554.1 - 0.05 13.8 2.4 3.9 7.7 0.2 2.8 2 1 0 2 2 2 0 Chorion protein S16 PGM_PMM_I PF02878.16 KEZ38555.1 - 2.5e-31 108.2 0.1 1.6e-26 92.6 0.1 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KEZ38555.1 - 6.3e-22 78.1 0.1 2.4e-21 76.3 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KEZ38555.1 - 1.7e-18 66.8 0.0 2.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KEZ38555.1 - 1.8e-05 24.8 0.0 5.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain UPRTase PF14681.6 KEZ38556.1 - 1.1e-57 194.8 0.0 1.3e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEZ38556.1 - 7.1e-10 38.6 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 KEZ38556.1 - 0.096 12.6 0.5 0.13 12.1 0.5 1.2 1 0 0 1 1 1 0 NAD(P)H-binding DeoC PF01791.9 KEZ38557.1 - 3.8e-17 62.7 2.3 4.3e-17 62.5 2.3 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KEZ38557.1 - 3.2e-06 26.6 0.6 5.9e-06 25.7 0.6 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KEZ38557.1 - 0.097 12.1 0.2 0.097 12.1 0.2 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein UreE_C PF05194.12 KEZ38557.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Adenine_glyco PF03352.13 KEZ38558.1 - 1.9e-64 216.7 0.0 2.2e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase A_deaminase PF00962.22 KEZ38559.1 - 2e-84 283.8 0.0 2.3e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Glycos_transf_3 PF00591.21 KEZ38560.1 - 4.7e-36 124.7 4.4 6.2e-36 124.3 4.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 KEZ38560.1 - 2.1e-18 65.7 0.1 2.1e-18 65.7 0.1 1.9 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 KEZ38560.1 - 3.6e-15 55.6 0.1 2.9e-14 52.7 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain Biotin_lipoyl PF00364.22 KEZ38560.1 - 0.069 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme Reprolysin_2 PF13574.6 KEZ38560.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like dCMP_cyt_deam_1 PF00383.23 KEZ38561.1 - 5.9e-07 29.3 0.1 7.3e-06 25.8 0.1 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KEZ38561.1 - 5.6e-05 23.4 0.8 0.022 15.0 0.1 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KEZ38561.1 - 0.029 14.0 0.1 0.21 11.1 0.1 1.8 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Pkinase PF00069.25 KEZ38562.1 - 7.6e-39 133.7 0.0 1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38562.1 - 3e-24 85.7 0.0 3.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ38562.1 - 7.3e-05 22.8 1.3 0.2 11.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family PsbP PF01789.16 KEZ38562.1 - 0.00078 19.6 0.0 0.0048 17.0 0.0 2.1 1 1 0 1 1 1 1 PsbP Kinase-like PF14531.6 KEZ38562.1 - 0.015 14.6 0.0 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KEZ38562.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ38562.1 - 0.037 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KEZ38562.1 - 0.074 11.8 1.6 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Myc_N PF01056.18 KEZ38562.1 - 0.28 11.0 6.7 0.41 10.5 6.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Paramyxo_ncap PF00973.19 KEZ38562.1 - 5.6 5.8 4.7 8.1 5.2 4.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Merozoite_SPAM PF07133.11 KEZ38562.1 - 7.1 6.6 14.4 11 6.0 14.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 KEZ38562.1 - 7.7 4.7 8.2 11 4.2 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KEZ38563.1 - 2.3e-45 155.0 0.0 3.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38563.1 - 3.1e-29 102.1 0.0 3.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ38563.1 - 8.3e-05 22.0 0.0 0.008 15.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KEZ38563.1 - 0.0016 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KEZ38563.1 - 0.0073 16.2 5.7 0.051 13.5 0.3 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ38563.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KEZ38563.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sdh_cyt PF01127.22 KEZ38564.1 - 1.8e-21 76.4 5.7 2.3e-21 76.1 5.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 KEZ38564.1 - 0.00054 20.1 2.4 0.00077 19.6 2.3 1.4 1 1 0 1 1 1 1 Fumarate reductase subunit D Fumarate_red_C PF02300.17 KEZ38564.1 - 0.033 14.3 7.1 0.093 12.8 5.9 1.9 1 1 1 2 2 2 0 Fumarate reductase subunit C Ferric_reduct PF01794.19 KEZ38564.1 - 0.14 12.3 4.8 0.3 11.2 4.8 1.7 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Sdh_cyt PF01127.22 KEZ38565.1 - 1.1e-13 51.2 3.9 1.4e-13 51.0 3.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2768 PF10966.8 KEZ38565.1 - 0.00022 21.6 0.1 0.42 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2768) DUF2156 PF09924.9 KEZ38565.1 - 0.15 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) FAD_binding_2 PF00890.24 KEZ38566.1 - 3.5e-116 388.7 1.9 4.8e-116 388.3 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KEZ38566.1 - 1.3e-41 141.5 0.1 2.1e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term HI0933_like PF03486.14 KEZ38566.1 - 1.8e-05 23.6 3.2 0.23 10.1 1.4 3.4 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.17 KEZ38566.1 - 0.00018 20.9 1.5 0.36 10.0 0.1 3.1 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.14 KEZ38566.1 - 0.00089 18.6 5.8 0.029 13.6 1.9 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ38566.1 - 0.0062 16.2 4.6 0.014 15.0 2.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ38566.1 - 1.1 8.3 3.1 7.4 5.5 2.8 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Fer2_3 PF13085.6 KEZ38567.1 - 2.9e-34 117.3 0.5 4.7e-34 116.7 0.0 1.6 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.6 KEZ38567.1 - 5.5e-12 45.6 2.0 9.5e-12 44.8 2.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ38567.1 - 5.1e-11 42.9 1.3 1e-10 41.9 1.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ38567.1 - 1.5e-06 28.2 6.3 0.00089 19.4 0.6 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KEZ38567.1 - 2.9e-06 27.7 4.3 2.9e-06 27.7 4.3 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ38567.1 - 3.3e-06 27.5 0.9 6.3e-06 26.6 0.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ38567.1 - 3.8e-05 24.5 1.2 0.026 15.4 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 KEZ38567.1 - 4e-05 23.2 7.1 0.00053 19.7 2.4 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 KEZ38567.1 - 0.0001 22.2 5.7 0.0007 19.6 0.8 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.6 KEZ38567.1 - 0.00015 21.9 0.6 0.055 13.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 KEZ38567.1 - 0.00059 19.6 1.6 0.88 9.4 0.0 2.3 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_4 PF12800.7 KEZ38567.1 - 0.00083 19.7 6.8 0.053 14.1 1.4 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ38567.1 - 0.0021 18.0 4.2 0.0021 18.0 4.2 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_3 PF12798.7 KEZ38567.1 - 0.0055 17.6 12.3 0.32 12.0 6.9 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KEZ38567.1 - 0.009 16.7 6.8 0.044 14.5 0.6 2.8 3 0 0 3 3 2 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 KEZ38567.1 - 0.022 14.9 3.2 0.042 14.0 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KEZ38567.1 - 0.11 13.1 0.7 0.11 13.1 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DEAD PF00270.29 KEZ38568.1 - 1e-15 58.0 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ38568.1 - 4.1e-15 56.1 0.0 1.1e-14 54.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ38568.1 - 2.2e-06 27.8 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 KEZ38568.1 - 0.00011 22.9 0.2 0.00024 21.8 0.2 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Pribosyltran PF00156.27 KEZ38568.1 - 0.0014 18.1 0.0 0.0033 17.0 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_30 PF13604.6 KEZ38568.1 - 0.0021 17.8 0.0 0.007 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain HTH_IclR PF09339.10 KEZ38568.1 - 2.6 7.9 6.7 5.7 6.8 0.3 3.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain adh_short PF00106.25 KEZ38569.1 - 1.3e-53 181.4 0.1 1.5e-53 181.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38569.1 - 3.2e-44 151.3 1.0 3.9e-44 150.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ38569.1 - 2.8e-14 53.4 0.3 4.3e-14 52.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ38569.1 - 0.00016 21.2 0.2 0.00057 19.4 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEZ38569.1 - 0.00026 21.2 0.0 0.00055 20.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEZ38569.1 - 0.064 13.5 0.3 2.4 8.4 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain FliG_M PF14841.6 KEZ38569.1 - 0.14 12.4 1.2 0.64 10.3 0.4 2.2 1 1 1 2 2 2 0 FliG middle domain NTP_transf_3 PF12804.7 KEZ38571.1 - 0.0097 16.3 0.1 0.012 16.0 0.1 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain PhdYeFM_antitox PF02604.19 KEZ38571.1 - 0.016 15.0 0.1 0.025 14.4 0.1 1.5 1 1 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Fic_N PF13784.6 KEZ38572.1 - 1.1e-22 79.9 1.5 1.5e-22 79.5 0.1 1.9 2 0 0 2 2 2 1 Fic/DOC family N-terminal Fic PF02661.18 KEZ38572.1 - 1.5e-21 77.1 0.0 4.5e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Fic/DOC family HTH_13 PF11972.8 KEZ38572.1 - 0.016 15.3 0.2 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 HTH DNA binding domain MarR_2 PF12802.7 KEZ38572.1 - 0.016 15.1 1.4 0.078 12.9 0.3 2.5 2 0 0 2 2 2 0 MarR family DOG1 PF14144.6 KEZ38572.1 - 0.12 12.6 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Seed dormancy control TPR_16 PF13432.6 KEZ38573.1 - 4.1 8.1 14.6 7.6 7.3 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat DDE_Tnp_4 PF13359.6 KEZ38578.1 - 3.1e-08 33.5 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KEZ38578.1 - 0.002 17.8 0.0 0.0028 17.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Frankia_sp._CeD-CeD/GCA_000732115.1_CeD_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Frankia_sp._CeD-CeD/GCA_000732115.1_CeD_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Frankia_sp._CeD-CeD/GCA_000732115.1_CeD_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Frankia_sp._CeD-CeD/GCA_000732115.1_CeD_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:55:29 2019 # [ok]